-- dump date   	20140619_082805
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
511145000001	bifunctional aspartokinase I/homoserine dehydrogenase I; Provisional; Region: thrA; PRK09436
511145000002	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
511145000003	putative catalytic residues [active]
511145000004	putative nucleotide binding site [chemical binding]; other site
511145000005	putative aspartate binding site [chemical binding]; other site
511145000006	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA-like_1; cd04921
511145000007	dimer interface [polypeptide binding]; other site
511145000008	putative threonine allosteric regulatory site; other site
511145000009	ACT domains of the bifunctional enzyme aspartokinase (AK) - homoserine dehydrogenase (HSDH); Region: ACT_AKi-HSDH-ThrA_2; cd04922
511145000010	putative threonine allosteric regulatory site; other site
511145000011	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
511145000012	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
511145000013	homoserine kinase; Region: thrB; TIGR00191
511145000014	Protein of unknown function; Region: YhfT; pfam10797
511145000015	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
511145000016	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
511145000017	threonine synthase; Validated; Region: PRK09225
511145000018	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
511145000019	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145000020	catalytic residue [active]
511145000021	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
511145000022	hypothetical protein; Validated; Region: PRK02101
511145000023	Sodium:alanine symporter family; Region: Na_Ala_symp; pfam01235
511145000024	transaldolase-like protein; Provisional; Region: PTZ00411
511145000025	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
511145000026	active site
511145000027	dimer interface [polypeptide binding]; other site
511145000028	catalytic residue [active]
511145000029	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
511145000030	MPT binding site; other site
511145000031	trimer interface [polypeptide binding]; other site
511145000032	hypothetical protein; Provisional; Region: PRK10659
511145000033	hypothetical protein; Provisional; Region: PRK10236
511145000034	Domain of unknown function (DUF3944); Region: DUF3944; pfam13099
511145000035	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4735
511145000036	hypothetical protein; Provisional; Region: PRK10154
511145000037	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
511145000038	Nucleotide-binding domain of human HSPA9, Escherichia coli DnaK, and similar proteins; Region: HSPA9-like_NBD; cd11733
511145000039	nucleotide binding site [chemical binding]; other site
511145000040	NEF interaction site [polypeptide binding]; other site
511145000041	SBD interface [polypeptide binding]; other site
511145000042	chaperone protein DnaJ; Provisional; Region: PRK10767
511145000043	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
511145000044	HSP70 interaction site [polypeptide binding]; other site
511145000045	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
511145000046	substrate binding site [polypeptide binding]; other site
511145000047	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
511145000048	Zn binding sites [ion binding]; other site
511145000049	dimer interface [polypeptide binding]; other site
511145000050	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
511145000051	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145000052	Hok/gef family; Region: HOK_GEF; pfam01848
511145000053	Hok/gef family; Region: HOK_GEF; pfam01848
511145000054	pH-dependent sodium/proton antiporter; Reviewed; Region: nhaA; PRK09561
511145000055	transcriptional activator NhaR; Provisional; Region: nhaR; PRK11062
511145000056	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145000057	The C-terminal substrate binding domain of LysR-type transcriptional activator of the nhaA gene, encoding Na+/H+ antiporter, contains the type 2 periplasmic binding fold; Region: PBP2_NhaR; cd08429
511145000058	putative dimerization interface [polypeptide binding]; other site
511145000059	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145000060	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145000061	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145000062	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145000063	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
511145000064	Protein of unknown function (DUF2575); Region: DUF2575; pfam10837
511145000065	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
511145000066	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
511145000067	active site
511145000068	Riboflavin kinase; Region: Flavokinase; smart00904
511145000069	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK05743
511145000070	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
511145000071	active site
511145000072	HIGH motif; other site
511145000073	KMSKS motif; other site
511145000074	Anticodon-binding domain of bacterial and eukaryotic mitochondrial isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_BEm; cd07960
511145000075	tRNA binding surface [nucleotide binding]; other site
511145000076	anticodon binding site; other site
511145000077	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
511145000078	lipoprotein signal peptidase; Reviewed; Region: lspA; PRK00376
511145000079	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK15095
511145000080	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
511145000081	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944
511145000082	Fe-S cluster binding site [ion binding]; other site
511145000083	substrate binding site [chemical binding]; other site
511145000084	catalytic site [active]
511145000085	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
511145000086	active site
511145000087	tetramer interface [polypeptide binding]; other site
511145000088	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
511145000089	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
511145000090	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
511145000091	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
511145000092	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; smart01097
511145000093	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
511145000094	catalytic site [active]
511145000095	subunit interface [polypeptide binding]; other site
511145000096	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
511145000097	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
511145000098	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
511145000099	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; smart01096
511145000100	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
511145000101	ATP-grasp domain; Region: ATP-grasp_4; cl17255
511145000102	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
511145000103	IMP binding site; other site
511145000104	dimer interface [polypeptide binding]; other site
511145000105	interdomain contacts; other site
511145000106	partial ornithine binding site; other site
511145000107	DNA-binding transcriptional activator CaiF; Provisional; Region: PRK11476
511145000108	carnitine operon protein CaiE; Provisional; Region: PRK13627
511145000109	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
511145000110	putative trimer interface [polypeptide binding]; other site
511145000111	putative metal binding site [ion binding]; other site
511145000112	carnitinyl-CoA dehydratase; Provisional; Region: PRK03580
511145000113	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145000114	substrate binding site [chemical binding]; other site
511145000115	oxyanion hole (OAH) forming residues; other site
511145000116	trimer interface [polypeptide binding]; other site
511145000117	putative crotonobetaine/carnitine-CoA ligase; Validated; Region: caiC; PRK08008
511145000118	Uncharacterized subfamily of fatty acid CoA ligase (FACL); Region: FACL_DitJ_like; cd05934
511145000119	acyl-activating enzyme (AAE) consensus motif; other site
511145000120	putative AMP binding site [chemical binding]; other site
511145000121	putative active site [active]
511145000122	putative CoA binding site [chemical binding]; other site
511145000123	crotonobetainyl-CoA:carnitine CoA-transferase; Provisional; Region: PRK03525
511145000124	crotonobetainyl-CoA dehydrogenase; Validated; Region: PRK03354
511145000125	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
511145000126	active site
511145000127	L-carnitine/gamma-butyrobetaine antiporter; Provisional; Region: PRK03356
511145000128	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
511145000129	Ligand binding site [chemical binding]; other site
511145000130	putative electron transfer flavoprotein FixB; Provisional; Region: fixB; PRK03363
511145000131	Electron transfer flavoprotein domain; Region: ETF; pfam01012
511145000132	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
511145000133	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145000134	putative oxidoreductase FixC; Provisional; Region: PRK10157
511145000135	ferredoxin-like protein FixX; Provisional; Region: PRK15449
511145000136	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145000137	Sugar (and other) transporter; Region: Sugar_tr; pfam00083
511145000138	putative substrate translocation pore; other site
511145000139	glutathione-regulated potassium-efflux system ancillary protein KefF; Provisional; Region: PRK00871
511145000140	glutathione-regulated potassium-efflux system protein KefC; Provisional; Region: PRK03562
511145000141	transporter, monovalent cation:proton antiporter-2 (CPA2) family; Region: 2a37; TIGR00932
511145000142	TrkA-N domain; Region: TrkA_N; pfam02254
511145000143	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
511145000144	folate binding site [chemical binding]; other site
511145000145	NADP+ binding site [chemical binding]; other site
511145000146	bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Region: apaH; TIGR00668
511145000147	Escherichia coli ApaH and related proteins, metallophosphatase domain; Region: MPP_ApaH; cd07422
511145000148	active site
511145000149	metal binding site [ion binding]; metal-binding site
511145000150	CO2+/MG2+ efflux protein ApaG; Reviewed; Region: apaG; PRK05461
511145000151	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
511145000152	4-hydroxythreonine-4-phosphate dehydrogenase; Reviewed; Region: pdxA; PRK00232
511145000153	peptidyl-prolyl cis-trans isomerase SurA; Provisional; Region: PRK10770
511145000154	SurA N-terminal domain; Region: SurA_N; pfam09312
511145000155	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
511145000156	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
511145000157	LPS assembly outer membrane complex protein LptD; Provisional; Region: PRK03761
511145000158	OstA-like protein; Region: OstA; pfam03968
511145000159	Organic solvent tolerance protein; Region: OstA_C; pfam04453
511145000160	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
511145000161	N-terminal tellurium resistance protein terB-like domain of heat shock DnaJ-like proteins; Region: terB_like_DjlA; cd07316
511145000162	putative metal binding site [ion binding]; other site
511145000163	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
511145000164	HSP70 interaction site [polypeptide binding]; other site
511145000165	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
511145000166	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
511145000167	active site
511145000168	ATP-dependent helicase HepA; Validated; Region: PRK04914
511145000169	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145000170	ATP binding site [chemical binding]; other site
511145000171	putative Mg++ binding site [ion binding]; other site
511145000172	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145000173	nucleotide binding region [chemical binding]; other site
511145000174	ATP-binding site [chemical binding]; other site
511145000175	RNA polymerase recycling family C-terminal; Region: RapA_C; pfam12137
511145000176	DNA polymerase II; Reviewed; Region: PRK05762
511145000177	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase II and similar bacterial family-B DNA polymerases; Region: DNA_polB_II_exo; cd05784
511145000178	active site
511145000179	catalytic site [active]
511145000180	substrate binding site [chemical binding]; other site
511145000181	DNA polymerase type-II subfamily catalytic domain. Bacteria contain five DNA polymerases (I, II, III, IV and V). DNA polymerase II (Pol II) is a prototype for the B-family of polymerases. The role of Pol II in a variety of cellular activities, such as...; Region: POLBc_Pol_II; cd05537
511145000182	active site
511145000183	metal-binding site
511145000184	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
511145000185	intersubunit interface [polypeptide binding]; other site
511145000186	active site
511145000187	Zn2+ binding site [ion binding]; other site
511145000188	L-arabinose isomerase; Provisional; Region: PRK02929
511145000189	L-Arabinose isomerase (AI) catalyzes the isomerization of L-arabinose to L-ribulose, the first reaction in its conversion into D-xylulose-5-phosphate, an intermediate in the pentose phosphate pathway, which allows L-arabinose to be used as a carbon...; Region: L-arabinose_isomerase; cd03557
511145000190	putative hexamer (dimer of trimers) interface [polypeptide binding]; other site
511145000191	trimer interface [polypeptide binding]; other site
511145000192	putative substrate binding site [chemical binding]; other site
511145000193	putative metal binding site [ion binding]; other site
511145000194	ribulokinase; Provisional; Region: PRK04123
511145000195	Ribulokinases; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_RBK; cd07781
511145000196	N- and C-terminal domain interface [polypeptide binding]; other site
511145000197	active site
511145000198	MgATP binding site [chemical binding]; other site
511145000199	catalytic site [active]
511145000200	metal binding site [ion binding]; metal-binding site
511145000201	carbohydrate binding site [chemical binding]; other site
511145000202	homodimer interface [polypeptide binding]; other site
511145000203	DNA-binding transcriptional regulator AraC; Provisional; Region: PRK10572
511145000204	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
511145000205	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145000206	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145000207	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
511145000208	thiamine transporter ATP-binding subunit; Provisional; Region: thiQ; PRK10771
511145000209	ATP-binding cassette domain of the thiamine transport system; Region: ABC_ThiQ_thiamine_transporter; cd03298
511145000210	Walker A/P-loop; other site
511145000211	ATP binding site [chemical binding]; other site
511145000212	Q-loop/lid; other site
511145000213	ABC transporter signature motif; other site
511145000214	Walker B; other site
511145000215	D-loop; other site
511145000216	H-loop/switch region; other site
511145000217	thiamine transporter membrane protein; Reviewed; Region: thiP; PRK09433
511145000218	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145000219	dimer interface [polypeptide binding]; other site
511145000220	conserved gate region; other site
511145000221	putative PBP binding loops; other site
511145000222	ABC-ATPase subunit interface; other site
511145000223	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145000224	dimer interface [polypeptide binding]; other site
511145000225	conserved gate region; other site
511145000226	putative PBP binding loops; other site
511145000227	ABC-ATPase subunit interface; other site
511145000228	thiamine transporter substrate binding subunit; Provisional; Region: tbpA; PRK11205
511145000229	transcriptional regulator SgrR; Provisional; Region: PRK13626
511145000230	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
511145000231	The C-terminal solute-binding domain of DNA-binding transcriptional regulator SgrR is related to the ABC-type oligopeptide-binding proteins and contains the type 2 periplasmic-binding fold; Region: PBP2_SgrR_like; cd08507
511145000232	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145000233	sugar efflux transporter; Region: 2A0120; TIGR00899
511145000234	putative substrate translocation pore; other site
511145000235	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
511145000236	substrate binding site [chemical binding]; other site
511145000237	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
511145000238	substrate binding site [chemical binding]; other site
511145000239	ligand binding site [chemical binding]; other site
511145000240	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
511145000241	2-isopropylmalate synthase; Validated; Region: PRK00915
511145000242	2-isopropylmalate synthase (IPMS), N-terminal catalytic TIM barrel domain; Region: DRE_TIM_IPMS; cd07940
511145000243	active site
511145000244	catalytic residues [active]
511145000245	metal binding site [ion binding]; metal-binding site
511145000246	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
511145000247	leu operon leader peptide; Provisional; Region: PRK09925
511145000248	leucine transcriptional activator; Reviewed; Region: leuO; PRK09508
511145000249	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145000250	The C-terminal substrate binding domain of LysR-type transcriptional regulator LeuO, an activator of leucine synthesis operon, contains the type 2 periplasmic binding fold; Region: PBP2_LeuO; cd08466
511145000251	putative substrate binding pocket [chemical binding]; other site
511145000252	putative dimerization interface [polypeptide binding]; other site
511145000253	acetolactate synthase 3 catalytic subunit; Validated; Region: PRK07979
511145000254	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
511145000255	PYR/PP interface [polypeptide binding]; other site
511145000256	dimer interface [polypeptide binding]; other site
511145000257	TPP binding site [chemical binding]; other site
511145000258	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
511145000259	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
511145000260	TPP-binding site [chemical binding]; other site
511145000261	dimer interface [polypeptide binding]; other site
511145000262	acetolactate synthase 3 regulatory subunit; Reviewed; Region: ilvH; PRK11895
511145000263	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
511145000264	putative valine binding site [chemical binding]; other site
511145000265	dimer interface [polypeptide binding]; other site
511145000266	Small subunit of acetolactate synthase; Region: ALS_ss_C; pfam10369
511145000267	DNA-binding transcriptional regulator FruR; Provisional; Region: PRK11303
511145000268	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145000269	DNA binding site [nucleotide binding]
511145000270	domain linker motif; other site
511145000271	Ligand binding domain of DNA transcription repressor specific for fructose (FruR) and its close homologs; Region: PBP1_FruR; cd06274
511145000272	dimerization interface [polypeptide binding]; other site
511145000273	ligand binding site [chemical binding]; other site
511145000274	mraZ protein; Region: TIGR00242
511145000275	MraZ protein; Region: MraZ; pfam02381
511145000276	MraZ protein; Region: MraZ; pfam02381
511145000277	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
511145000278	cell division protein FtsL; Provisional; Region: PRK10772
511145000279	peptidoglycan synthase FtsI; Provisional; Region: PRK15105
511145000280	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
511145000281	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
511145000282	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
511145000283	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
511145000284	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145000285	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145000286	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Reviewed; Region: murF; PRK10773
511145000287	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
511145000288	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145000289	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145000290	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
511145000291	Mg++ binding site [ion binding]; other site
511145000292	putative catalytic motif [active]
511145000293	putative substrate binding site [chemical binding]; other site
511145000294	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK03806
511145000295	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145000296	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145000297	cell division protein FtsW; Provisional; Region: PRK10774
511145000298	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
511145000299	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
511145000300	active site
511145000301	homodimer interface [polypeptide binding]; other site
511145000302	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
511145000303	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
511145000304	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145000305	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145000306	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
511145000307	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
511145000308	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
511145000309	cell division protein FtsQ; Provisional; Region: PRK10775
511145000310	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
511145000311	Cell division protein FtsQ; Region: FtsQ; pfam03799
511145000312	cell division protein FtsA; Reviewed; Region: ftsA; PRK09472
511145000313	Cell division protein FtsA; Region: FtsA; pfam14450
511145000314	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145000315	Cell division protein FtsA; Region: FtsA; pfam14450
511145000316	cell division protein FtsZ; Validated; Region: PRK09330
511145000317	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
511145000318	nucleotide binding site [chemical binding]; other site
511145000319	SulA interaction site; other site
511145000320	cell division protein FtsZ, alphaProteobacterial C-terminal extension; Region: FtsZ_alphas_C; TIGR03483
511145000321	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Reviewed; Region: lpxC; PRK13186
511145000322	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
511145000323	SecA regulator SecM; Provisional; Region: PRK02943
511145000324	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
511145000325	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
511145000326	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
511145000327	SEC-C motif; Region: SEC-C; pfam02810
511145000328	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
511145000329	active site
511145000330	8-oxo-dGMP binding site [chemical binding]; other site
511145000331	nudix motif; other site
511145000332	metal binding site [ion binding]; metal-binding site
511145000333	DNA gyrase inhibitor; Reviewed; Region: PRK00418
511145000334	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4582
511145000335	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
511145000336	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
511145000337	CoA-binding site [chemical binding]; other site
511145000338	ATP-binding [chemical binding]; other site
511145000339	guanosine 5'-monophosphate oxidoreductase; Provisional; Region: PRK05096
511145000340	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
511145000341	active site
511145000342	type IV pilin biogenesis protein; Provisional; Region: PRK10573
511145000343	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
511145000344	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
511145000345	hypothetical protein; Provisional; Region: PRK10436
511145000346	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
511145000347	Walker A motif; other site
511145000348	ATP binding site [chemical binding]; other site
511145000349	Walker B motif; other site
511145000350	putative major pilin subunit; Provisional; Region: PRK10574
511145000351	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
511145000352	Pilin (bacterial filament); Region: Pilin; pfam00114
511145000353	quinolinate phosphoribosyltransferase; Validated; Region: PRK09016
511145000354	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
511145000355	dimerization interface [polypeptide binding]; other site
511145000356	active site
511145000357	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
511145000358	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
511145000359	amidase catalytic site [active]
511145000360	Zn binding residues [ion binding]; other site
511145000361	substrate binding site [chemical binding]; other site
511145000362	regulatory protein AmpE; Provisional; Region: PRK10987
511145000363	aromatic amino acid transporter; Provisional; Region: PRK10238
511145000364	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145000365	transcriptional regulator PdhR; Reviewed; Region: pdhR; PRK09464
511145000366	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145000367	DNA-binding site [nucleotide binding]; DNA binding site
511145000368	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145000369	pyruvate dehydrogenase subunit E1; Reviewed; Region: aceE; PRK09405
511145000370	Thiamine pyrophosphate (TPP) family, E1 of E. coli PDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the Escherichia coli pyruvate dehydrogenase multienzyme complex (PDC). PDC catalyzes the oxidative...; Region: TPP_E1_EcPDC_like; cd02017
511145000371	dimer interface [polypeptide binding]; other site
511145000372	TPP-binding site [chemical binding]; other site
511145000373	pyruvate dehydrogenase dihydrolipoyltransacetylase; Validated; Region: aceF; PRK11854
511145000374	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
511145000375	E3 interaction surface; other site
511145000376	lipoyl attachment site [posttranslational modification]; other site
511145000377	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
511145000378	E3 interaction surface; other site
511145000379	lipoyl attachment site [posttranslational modification]; other site
511145000380	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
511145000381	E3 interaction surface; other site
511145000382	lipoyl attachment site [posttranslational modification]; other site
511145000383	e3 binding domain; Region: E3_binding; pfam02817
511145000384	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
511145000385	dihydrolipoamide dehydrogenase; Reviewed; Region: PRK06467
511145000386	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145000387	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145000388	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
511145000389	Protein of unknown function (DUF3300); Region: DUF3300; pfam11737
511145000390	Protein of unknown function (DUF3106); Region: DUF3106; pfam11304
511145000391	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated; Region: PRK09238
511145000392	Aconitate B N-terminal domain; Region: Aconitase_B_N; pfam11791
511145000393	Aconitase B swivel domain. Aconitate hydratase B is involved in energy metabolism as part of the TCA cycle. It catalyses the formation of cis-aconitate from citrate. This is the aconitase swivel domain, which undergoes swivelling conformational change in...; Region: AcnB_Swivel; cd01576
511145000394	substrate binding site [chemical binding]; other site
511145000395	Aconitate hydratase B catalyses the formation of cis-aconitate from citrate as part of the TCA cycle; Region: AcnB; cd01581
511145000396	substrate binding site [chemical binding]; other site
511145000397	ligand binding site [chemical binding]; other site
511145000398	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3112
511145000399	S-adenosylmethionine decarboxylase; Provisional; Region: PRK05462
511145000400	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145000401	S-adenosylmethionine binding site [chemical binding]; other site
511145000402	Bacterial chaperone lipoprotein (PulS_OutS); Region: PulS_OutS; cl09898
511145000403	multicopper oxidase; Provisional; Region: PRK10965
511145000404	The first Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_1_CueO_FtsP; cd04232
511145000405	Domain 2 interface [polypeptide binding]; other site
511145000406	Domain 3 interface [polypeptide binding]; other site
511145000407	trinuclear Cu binding site [ion binding]; other site
511145000408	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
511145000409	Domain 1 interface [polypeptide binding]; other site
511145000410	Domain 3 interface [polypeptide binding]; other site
511145000411	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
511145000412	Domain 2 interface [polypeptide binding]; other site
511145000413	Domain 1 interface [polypeptide binding]; other site
511145000414	Type 1 (T1) Cu binding site [ion binding]; other site
511145000415	trinuclear Cu binding site [ion binding]; other site
511145000416	Glucose dehydrogenase [Carbohydrate transport and metabolism]; Region: Gcd; COG4993
511145000417	Membrane-bound PQQ-dependent glucose dehydrogenase; Region: PQQ_mGDH; cd10280
511145000418	Trp docking motif [polypeptide binding]; other site
511145000419	putative active site [active]
511145000420	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145000421	active site
511145000422	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeA; cd00883
511145000423	active site clefts [active]
511145000424	zinc binding site [ion binding]; other site
511145000425	dimer interface [polypeptide binding]; other site
511145000426	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
511145000427	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
511145000428	Walker A/P-loop; other site
511145000429	ATP binding site [chemical binding]; other site
511145000430	Q-loop/lid; other site
511145000431	ABC transporter signature motif; other site
511145000432	Walker B; other site
511145000433	D-loop; other site
511145000434	H-loop/switch region; other site
511145000435	inner membrane transport permease; Provisional; Region: PRK15066
511145000436	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
511145000437	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
511145000438	active pocket/dimerization site; other site
511145000439	active site
511145000440	phosphorylation site [posttranslational modification]
511145000441	Putative catalytic polysaccharide deacetylase domain of uncharacterized protein yadE and similar proteins; Region: CE4_yadE_5s; cd10966
511145000442	putative active site [active]
511145000443	putative metal binding site [ion binding]; other site
511145000444	Aspartate alpha-decarboxylase or L-aspartate 1-decarboxylase, a pyruvoyl group-dependent  decarboxylase in beta-alanine production; Region: Asp_decarbox; cd06919
511145000445	tetramerization interface [polypeptide binding]; other site
511145000446	active site
511145000447	Uncharacterized conserved protein [Function unknown]; Region: COG5464
511145000448	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
511145000449	Pantoate-beta-alanine ligase; Region: PanC; cd00560
511145000450	active site
511145000451	ATP-binding site [chemical binding]; other site
511145000452	pantoate-binding site; other site
511145000453	HXXH motif; other site
511145000454	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
511145000455	oligomerization interface [polypeptide binding]; other site
511145000456	active site
511145000457	metal binding site [ion binding]; metal-binding site
511145000458	putative fimbrial-like adhesin protein; Provisional; Region: PRK09723
511145000459	putative fimbrial protein StaF; Provisional; Region: PRK15262
511145000460	putative fimbrial protein StaE; Provisional; Region: PRK15263
511145000461	Fimbrial protein; Region: Fimbrial; cl01416
511145000462	putative fimbrial outer membrane usher protein; Provisional; Region: PRK09828
511145000463	PapC N-terminal domain; Region: PapC_N; pfam13954
511145000464	Outer membrane usher protein; Region: Usher; pfam00577
511145000465	PapC C-terminal domain; Region: PapC_C; pfam13953
511145000466	putative chaperone protein EcpD; Provisional; Region: PRK09926
511145000467	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145000468	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145000469	Fimbrial protein; Region: Fimbrial; cl01416
511145000470	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
511145000471	catalytic center binding site [active]
511145000472	ATP binding site [chemical binding]; other site
511145000473	poly(A) polymerase I; Provisional; Region: pcnB; PRK11623
511145000474	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
511145000475	active site
511145000476	NTP binding site [chemical binding]; other site
511145000477	metal binding triad [ion binding]; metal-binding site
511145000478	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
511145000479	Polymerase A arginine-rich C-terminus; Region: PolyA_pol_arg_C; pfam12626
511145000480	glutamyl-Q tRNA(Asp) synthetase; Reviewed; Region: PRK05710
511145000481	tRNA synthetases class I (E and Q), catalytic domain; Region: tRNA-synt_1c; pfam00749
511145000482	active site
511145000483	nucleotide binding site [chemical binding]; other site
511145000484	HIGH motif; other site
511145000485	KMSKS motif; other site
511145000486	RNA polymerase-binding transcription factor; Provisional; Region: dksA; PRK10778
511145000487	putative DNA-binding transcriptional regulator; Reviewed; Region: PRK00347
511145000488	2'-5' RNA ligase; Provisional; Region: PRK15124
511145000489	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
511145000490	LigT like Phosphoesterase; Region: LigT_PEase; pfam02834
511145000491	ATP-dependent RNA helicase HrpB; Provisional; Region: PRK11664
511145000492	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145000493	ATP binding site [chemical binding]; other site
511145000494	putative Mg++ binding site [ion binding]; other site
511145000495	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145000496	nucleotide binding region [chemical binding]; other site
511145000497	ATP-binding site [chemical binding]; other site
511145000498	Helicase associated domain (HA2) Add an annotation; Region: HA2; smart00847
511145000499	ATP-dependent helicase C-terminal; Region: HrpB_C; pfam08482
511145000500	bifunctional glycosyl transferase/transpeptidase; Reviewed; Region: mrcB; PRK09506
511145000501	Transmembrane domain of transglycosylase PBP1 at N-terminal; Region: PBP1_TM; pfam14812
511145000502	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
511145000503	Transglycosylase; Region: Transgly; pfam00912
511145000504	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
511145000505	ferrichrome outer membrane transporter; Provisional; Region: PRK10044
511145000506	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145000507	N-terminal plug; other site
511145000508	ligand-binding site [chemical binding]; other site
511145000509	iron-hydroxamate transporter ATP-binding subunit; Provisional; Region: PRK10575
511145000510	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
511145000511	Walker A/P-loop; other site
511145000512	ATP binding site [chemical binding]; other site
511145000513	Q-loop/lid; other site
511145000514	ABC transporter signature motif; other site
511145000515	Walker B; other site
511145000516	D-loop; other site
511145000517	H-loop/switch region; other site
511145000518	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
511145000519	Periplasmic binding protein; Region: Peripla_BP_2; pfam01497
511145000520	siderophore binding site; other site
511145000521	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
511145000522	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145000523	ABC-ATPase subunit  interface; other site
511145000524	dimer interface [polypeptide binding]; other site
511145000525	putative PBP binding regions; other site
511145000526	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145000527	ABC-ATPase subunit  interface; other site
511145000528	dimer interface [polypeptide binding]; other site
511145000529	putative PBP binding regions; other site
511145000530	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
511145000531	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145000532	inhibitor-cofactor binding pocket; inhibition site
511145000533	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145000534	catalytic residue [active]
511145000535	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
511145000536	Cl- selectivity filter; other site
511145000537	Cl- binding residues [ion binding]; other site
511145000538	pore gating glutamate residue; other site
511145000539	dimer interface [polypeptide binding]; other site
511145000540	H+/Cl- coupling transport residue; other site
511145000541	iron-sulfur cluster insertion protein ErpA; Provisional; Region: PRK13623
511145000542	hypothetical protein; Provisional; Region: PRK10578
511145000543	UPF0126 domain; Region: UPF0126; pfam03458
511145000544	UPF0126 domain; Region: UPF0126; pfam03458
511145000545	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
511145000546	Cobalamin binding protein BtuF.  These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species.  They belong to the TroA superfamily of helical backbone metal receptor...; Region: BtuF; cd01144
511145000547	cobalamin binding residues [chemical binding]; other site
511145000548	putative BtuC binding residues; other site
511145000549	dimer interface [polypeptide binding]; other site
511145000550	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
511145000551	deoxyguanosinetriphosphate triphosphohydrolase; Provisional; Region: dgt; PRK04926
511145000552	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145000553	Zn2+ binding site [ion binding]; other site
511145000554	Mg2+ binding site [ion binding]; other site
511145000555	Phosphohydrolase-associated domain; Region: HD_assoc; pfam13286
511145000556	serine endoprotease; Provisional; Region: PRK10942
511145000557	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
511145000558	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
511145000559	protein binding site [polypeptide binding]; other site
511145000560	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
511145000561	protein binding site [polypeptide binding]; other site
511145000562	carbohydrate diacid transcriptional activator CdaR; Provisional; Region: PRK11477
511145000563	Putative sugar diacid recognition; Region: Diacid_rec; pfam05651
511145000564	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
511145000565	hypothetical protein; Provisional; Region: PRK13677
511145000566	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
511145000567	putative active site [active]
511145000568	putative metal binding site [ion binding]; other site
511145000569	2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Provisional; Region: dapD; PRK11830
511145000570	Tetrahydrodipicolinate N-succinyltransferase N-terminal; Region: THDPS_N_2; pfam14805
511145000571	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
511145000572	trimer interface [polypeptide binding]; other site
511145000573	active site
511145000574	substrate binding site [chemical binding]; other site
511145000575	CoA binding site [chemical binding]; other site
511145000576	PII uridylyl-transferase; Provisional; Region: PRK05007
511145000577	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
511145000578	metal binding triad; other site
511145000579	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
511145000580	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145000581	Zn2+ binding site [ion binding]; other site
511145000582	Mg2+ binding site [ion binding]; other site
511145000583	ACT domain family, ACT_UUR-like_1, includes the first of two C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_UUR-like_1; cd04900
511145000584	C-terminal ACT domains of the bacterial signal-transducing uridylyltransferase /uridylyl-removing (UUR) enzyme, GlnD and related domains; Region: ACT_ACR-UUR-like_2; cd04899
511145000585	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
511145000586	active site
511145000587	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
511145000588	rRNA interaction site [nucleotide binding]; other site
511145000589	S8 interaction site; other site
511145000590	putative laminin-1 binding site; other site
511145000591	elongation factor Ts; Provisional; Region: tsf; PRK09377
511145000592	UBA/TS-N domain; Region: UBA; pfam00627
511145000593	Bacterial virulence factor haemolysin; Region: SMP_2; cl11479
511145000594	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
511145000595	putative nucleotide binding site [chemical binding]; other site
511145000596	uridine monophosphate binding site [chemical binding]; other site
511145000597	homohexameric interface [polypeptide binding]; other site
511145000598	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
511145000599	hinge region; other site
511145000600	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: Dxr; TIGR00243
511145000601	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
511145000602	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
511145000603	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
511145000604	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
511145000605	active site
511145000606	dimer interface [polypeptide binding]; other site
511145000607	CDP-diglyceride synthase; Provisional; Region: cdsA; PRK11624
511145000608	zinc metallopeptidase RseP; Provisional; Region: PRK10779
511145000609	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
511145000610	active site
511145000611	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
511145000612	protein binding site [polypeptide binding]; other site
511145000613	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
511145000614	protein binding site [polypeptide binding]; other site
511145000615	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
511145000616	putative substrate binding region [chemical binding]; other site
511145000617	outer membrane protein assembly factor YaeT; Provisional; Region: PRK11067
511145000618	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145000619	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145000620	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145000621	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145000622	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145000623	Surface antigen; Region: Bac_surface_Ag; pfam01103
511145000624	periplasmic chaperone; Provisional; Region: PRK10780
511145000625	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional; Region: lpxD; PRK00892
511145000626	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
511145000627	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
511145000628	trimer interface [polypeptide binding]; other site
511145000629	active site
511145000630	UDP-GlcNAc binding site [chemical binding]; other site
511145000631	lipid binding site [chemical binding]; lipid-binding site
511145000632	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
511145000633	UDP-N-acetylglucosamine acyltransferase; Provisional; Region: PRK05289
511145000634	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
511145000635	active site
511145000636	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK00025
511145000637	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
511145000638	Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
511145000639	RNA/DNA hybrid binding site [nucleotide binding]; other site
511145000640	active site
511145000641	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
511145000642	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE1; Region: PHP_PolIIIA_DnaE1; cd07433
511145000643	putative active site [active]
511145000644	putative PHP Thumb interface [polypeptide binding]; other site
511145000645	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
511145000646	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
511145000647	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
511145000648	generic binding surface II; other site
511145000649	generic binding surface I; other site
511145000650	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
511145000651	lysine decarboxylase LdcC; Provisional; Region: PRK15399
511145000652	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
511145000653	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
511145000654	homodimer interface [polypeptide binding]; other site
511145000655	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145000656	catalytic residue [active]
511145000657	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
511145000658	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_1; cd08352
511145000659	putative metal binding site [ion binding]; other site
511145000660	tRNA(Ile)-lysidine synthetase; Provisional; Region: tilS; PRK10660
511145000661	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
511145000662	Ligand Binding Site [chemical binding]; other site
511145000663	TilS substrate binding domain; Region: TilS; pfam09179
511145000664	TilS substrate C-terminal domain; Region: TilS_C; pfam11734
511145000665	Rho-binding antiterminator; Provisional; Region: PRK11625
511145000666	hypothetical protein; Provisional; Region: PRK04964
511145000667	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4681
511145000668	hypothetical protein; Provisional; Region: PRK09256
511145000669	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
511145000670	lipoprotein involved with copper homeostasis and adhesion; Provisional; Region: PRK10523
511145000671	Uncharacterized lipoprotein NlpE involved in copper resistance [Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism]; Region: CutF; COG3015
511145000672	hypothetical protein; Provisional; Region: PRK11479
511145000673	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
511145000674	prolyl-tRNA synthetase; Provisional; Region: PRK09194
511145000675	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
511145000676	dimer interface [polypeptide binding]; other site
511145000677	motif 1; other site
511145000678	active site
511145000679	motif 2; other site
511145000680	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
511145000681	putative deacylase active site [active]
511145000682	motif 3; other site
511145000683	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
511145000684	anticodon binding site; other site
511145000685	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
511145000686	homodimer interaction site [polypeptide binding]; other site
511145000687	cofactor binding site; other site
511145000688	outer membrane lipoprotein; Reviewed; Region: rcsF; PRK10781
511145000689	DL-methionine transporter substrate-binding subunit; Provisional; Region: metQ; PRK11063
511145000690	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145000691	dimer interface [polypeptide binding]; other site
511145000692	conserved gate region; other site
511145000693	putative PBP binding loops; other site
511145000694	ABC-ATPase subunit interface; other site
511145000695	DL-methionine transporter ATP-binding subunit; Provisional; Region: metN; PRK11153
511145000696	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
511145000697	Walker A/P-loop; other site
511145000698	ATP binding site [chemical binding]; other site
511145000699	Q-loop/lid; other site
511145000700	ABC transporter signature motif; other site
511145000701	Walker B; other site
511145000702	D-loop; other site
511145000703	H-loop/switch region; other site
511145000704	This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; Region: NIL; smart00930
511145000705	D,D-heptose 1,7-bisphosphate phosphatase; Region: GmhB_yaeD; TIGR00213
511145000706	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145000707	active site
511145000708	motif I; other site
511145000709	motif II; other site
511145000710	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145000711	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145000712	active site
511145000713	catalytic tetrad [active]
511145000714	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145000715	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145000716	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA; cd08478
511145000717	putative effector binding pocket; other site
511145000718	dimerization interface [polypeptide binding]; other site
511145000719	hypothetical protein; Provisional; Region: PRK05421
511145000720	putative catalytic site [active]
511145000721	putative metal binding site [ion binding]; other site
511145000722	putative phosphate binding site [ion binding]; other site
511145000723	putative catalytic site [active]
511145000724	putative phosphate binding site [ion binding]; other site
511145000725	putative metal binding site [ion binding]; other site
511145000726	Methyltransferase domain; Region: Methyltransf_31; pfam13847
511145000727	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145000728	S-adenosylmethionine binding site [chemical binding]; other site
511145000729	membrane-bound lytic murein transglycosylase D; Provisional; Region: mltD; PRK10783
511145000730	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145000731	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145000732	catalytic residue [active]
511145000733	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145000734	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145000735	hydroxyacylglutathione hydrolase; Provisional; Region: PRK10241
511145000736	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145000737	RNase HI family found mainly in prokaryotes; Region: RNase_HI_prokaryote_like; cd09278
511145000738	RNA/DNA hybrid binding site [nucleotide binding]; other site
511145000739	active site
511145000740	DNA polymerase III, epsilon subunit, Proteobacterial; Region: dnaQ_proteo; TIGR01406
511145000741	DEDDh 3'-5' exonuclease domain of the epsilon subunit of Escherichia coli DNA polymerase III and similar proteins; Region: DNA_pol_III_epsilon_Ecoli_like; cd06131
511145000742	active site
511145000743	catalytic site [active]
511145000744	substrate binding site [chemical binding]; other site
511145000745	Xanthomonas campestris XC1258 and related proteins, members of the nitrilase superfamily (putative class 13 nitrilases); Region: Xc-1258_like; cd07575
511145000746	putative active site [active]
511145000747	catalytic triad [active]
511145000748	dimer interface [polypeptide binding]; other site
511145000749	multimer interface [polypeptide binding]; other site
511145000750	C-lysozyme inhibitor; Provisional; Region: PRK09993
511145000751	acyl-CoA dehydrogenase; Reviewed; Region: fadE; PRK09463
511145000752	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
511145000753	active site
511145000754	Domain of unknown function (DUF1974); Region: DUF1974; pfam09317
511145000755	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
511145000756	dimer interface [polypeptide binding]; other site
511145000757	active site
511145000758	Glutamine amidotransferases class-II (Gn-AT)_YafJ-type.  YafJ is a glutamine amidotransferase-like protein of unknown function found in prokaryotes, eukaryotes and archaea.  YafJ has a conserved structural fold similar to those of other class II...; Region: YafJ; cd01908
511145000759	putative active site [active]
511145000760	Glutamine amidotransferases class-II; Region: GATase_2; pfam00310
511145000761	putative dimer interface [polypeptide binding]; other site
511145000762	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3034
511145000763	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145000764	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3041
511145000765	RelB antitoxin; Region: RelB; pfam04221
511145000766	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
511145000767	NlpC/P60 family; Region: NLPC_P60; pfam00877
511145000768	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG1943
511145000769	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
511145000770	active site
511145000771	DNA polymerase IV; Validated; Region: PRK02406
511145000772	DNA binding site [nucleotide binding]
511145000773	putative antitoxin of the YafO-YafN toxin-antitoxin system; Provisional; Region: PRK09778
511145000774	putative toxin YafO; Provisional; Region: PRK09885
511145000775	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
511145000776	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145000777	Coenzyme A binding pocket [chemical binding]; other site
511145000778	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
511145000779	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
511145000780	metal binding site [ion binding]; metal-binding site
511145000781	dimer interface [polypeptide binding]; other site
511145000782	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145000783	active site
511145000784	Alpha/beta hydrolase of unknown function (DUF1100); Region: DUF1100; pfam06500
511145000785	fermentation/respiration switch protein; Reviewed; Region: frsA; PRK05077
511145000786	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
511145000787	trimer interface [polypeptide binding]; other site
511145000788	eyelet of channel; other site
511145000789	gamma-glutamyl kinase; Provisional; Region: PRK05429
511145000790	AAK_G5K_ProB: Glutamate-5-kinase (G5K) catalyzes glutamate-dependent ATP cleavage; G5K transfers the terminal phosphoryl group of ATP to the gamma-carboxyl group of glutamate, in the first and controlling step of proline (and, in mammals, ornithine)...; Region: AAK_G5K_ProB; cd04242
511145000791	nucleotide binding site [chemical binding]; other site
511145000792	homotetrameric interface [polypeptide binding]; other site
511145000793	putative phosphate binding site [ion binding]; other site
511145000794	putative allosteric binding site; other site
511145000795	PUA domain; Region: PUA; pfam01472
511145000796	Gamma-glutamyl phosphate reductase (GPR), aldehyde dehydrogenase families 18 and 19; Region: ALDH_F18-19_ProA-GPR; cd07079
511145000797	putative catalytic cysteine [active]
511145000798	cryptic prophage CP4-6
511145000799	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
511145000800	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
511145000801	Protein of unknown function (DUF987); Region: DUF987; pfam06174
511145000802	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
511145000803	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
511145000804	MPN+ (JAMM) motif; other site
511145000805	Zinc-binding site [ion binding]; other site
511145000806	Antirestriction protein; Region: Antirestrict; pfam03230
511145000807	Bacterial protein of unknown function (DUF905); Region: DUF905; pfam06006
511145000808	Predicted transcriptional regulator [Transcription]; Region: COG2378
511145000809	Domain of unknown function (DUF932); Region: DUF932; pfam06067
511145000810	Predicted GTPase [General function prediction only]; Region: COG3596
511145000811	YfjP GTPase; Region: YfjP; cd11383
511145000812	G1 box; other site
511145000813	GTP/Mg2+ binding site [chemical binding]; other site
511145000814	Switch I region; other site
511145000815	G2 box; other site
511145000816	Switch II region; other site
511145000817	G3 box; other site
511145000818	G4 box; other site
511145000819	G5 box; other site
511145000820	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
511145000821	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145000822	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
511145000823	dimerization interface [polypeptide binding]; other site
511145000824	substrate binding pocket [chemical binding]; other site
511145000825	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
511145000826	Helix-turn-helix domain; Region: HTH_38; pfam13936
511145000827	Homeodomain-like domain; Region: HTH_32; pfam13565
511145000828	Integrase core domain; Region: rve; pfam00665
511145000829	Transposase domain (DUF772); Region: DUF772; pfam05598
511145000830	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145000831	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145000832	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145000833	S-methylmethionine transporter; Provisional; Region: PRK11387
511145000834	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145000835	homocysteine methyltransferase; Provisional; Region: mmuM; PRK09485
511145000836	ferric transporter ATP-binding subunit; Provisional; Region: fbpC; PRK11432
511145000837	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145000838	Walker A/P-loop; other site
511145000839	ATP binding site [chemical binding]; other site
511145000840	Q-loop/lid; other site
511145000841	ABC transporter signature motif; other site
511145000842	Walker B; other site
511145000843	D-loop; other site
511145000844	H-loop/switch region; other site
511145000845	TOBE domain; Region: TOBE_2; pfam08402
511145000846	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145000847	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145000848	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145000849	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145000850	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145000851	Helix-turn-helix domain; Region: HTH_28; pfam13518
511145000852	Homeodomain-like domain; Region: HTH_32; pfam13565
511145000853	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: Tra5; COG2801
511145000854	Integrase core domain; Region: rve; pfam00665
511145000855	Integrase core domain; Region: rve_3; pfam13683
511145000856	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
511145000857	inhibitor site; inhibition site
511145000858	active site
511145000859	dimer interface [polypeptide binding]; other site
511145000860	catalytic residue [active]
511145000861	putative dehydratase; Provisional; Region: PRK08211
511145000862	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
511145000863	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145000864	putative substrate translocation pore; other site
511145000865	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
511145000866	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
511145000867	inhibitor binding site; inhibition site
511145000868	active site
511145000869	Protein of unknown function (DUF1349); Region: DUF1349; cl01397
511145000870	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145000871	Transcriptional regulator [Transcription]; Region: IclR; COG1414
511145000872	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145000873	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
511145000874	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
511145000875	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
511145000876	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145000877	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145000878	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145000879	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145000880	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
511145000881	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
511145000882	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cl17315
511145000883	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
511145000884	active site
511145000885	DNA binding site [nucleotide binding]
511145000886	Int/Topo IB signature motif; other site
511145000887	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
511145000888	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
511145000889	XdhC Rossmann domain; Region: XdhC_C; pfam13478
511145000890	Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion]; Region: CoxL; COG1529
511145000891	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
511145000892	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
511145000893	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
511145000894	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
511145000895	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; smart01092
511145000896	aldehyde oxidoreductase 2Fe-2S subunit; Provisional; Region: PRK11433
511145000897	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145000898	catalytic loop [active]
511145000899	iron binding site [ion binding]; other site
511145000900	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
511145000901	Predicted periplasmic/secreted protein [Function unknown]; Region: COG3477
511145000902	Predicted Fe-S-cluster oxidoreductase [General function prediction only]; Region: COG0727
511145000903	fimbrial outer membrane usher protein TcfC; Provisional; Region: PRK15310
511145000904	Outer membrane usher protein; Region: Usher; pfam00577
511145000905	Domain of unknown function (DUF4480); Region: DUF4480; pfam13715
511145000906	putative fimbrial protein TcfA; Provisional; Region: PRK15308
511145000907	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
511145000908	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145000909	DNA binding residues [nucleotide binding]
511145000910	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
511145000911	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
511145000912	Transposase; Region: HTH_Tnp_1; cl17663
511145000913	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145000914	putative transposase OrfB; Reviewed; Region: PHA02517
511145000915	HTH-like domain; Region: HTH_21; pfam13276
511145000916	Integrase core domain; Region: rve; pfam00665
511145000917	Integrase core domain; Region: rve_2; pfam13333
511145000918	Predicted membrane protein [Function unknown]; Region: COG3059
511145000919	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145000920	pyridine nucleotide-disulfide oxidoreductase; Provisional; Region: PRK08010
511145000921	Squalene epoxidase; Region: SE; cl17314
511145000922	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145000923	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
511145000924	Cupin; Region: Cupin_6; pfam12852
511145000925	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
511145000926	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145000927	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145000928	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
511145000929	Cysteine-rich domain; Region: CCG; pfam02754
511145000930	Cysteine-rich domain; Region: CCG; pfam02754
511145000931	iron-sulfur cluster-binding protein; Region: TIGR00273
511145000932	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
511145000933	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145000934	Domain of unknown function (DUF3390); Region: DUF3390; pfam11870
511145000935	Uncharacterized conserved protein [Function unknown]; Region: COG1556
511145000936	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145000937	choline dehydrogenase; Validated; Region: PRK02106
511145000938	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145000939	GMC oxidoreductase; Region: GMC_oxred_N; pfam00732
511145000940	GMC oxidoreductase; Region: GMC_oxred_C; pfam05199
511145000941	NAD+-dependent 4-trimethylaminobutyraldehyde dehydrogenase, ALDH family 9A1; Region: ALDH_F9_TMBADH; cd07090
511145000942	tetrameric interface [polypeptide binding]; other site
511145000943	NAD binding site [chemical binding]; other site
511145000944	catalytic residues [active]
511145000945	transcriptional regulator BetI; Validated; Region: PRK00767
511145000946	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145000947	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
511145000948	choline transport protein BetT; Provisional; Region: PRK09928
511145000949	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145000950	DNA binding residues [nucleotide binding]
511145000951	dimerization interface [polypeptide binding]; other site
511145000952	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145000953	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
511145000954	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145000955	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145000956	dimerization interface [polypeptide binding]; other site
511145000957	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
511145000958	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
511145000959	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
511145000960	Ankyrin repeats (3 copies); Region: Ank_2; pfam12796
511145000961	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
511145000962	Succinyl-CoA synthetase, alpha subunit [Energy production and conversion]; Region: SucD; COG0074
511145000963	Type 1 periplasmic binding fold superfamily; Region: Periplasmic_Binding_Protein_Type_1; cl10011
511145000964	CoA binding domain; Region: CoA_binding; pfam02629
511145000965	CoA-ligase; Region: Ligase_CoA; pfam00549
511145000966	Protein of unknown function (DUF1116); Region: DUF1116; pfam06545
511145000967	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
511145000968	putative substrate binding site [chemical binding]; other site
511145000969	nucleotide binding site [chemical binding]; other site
511145000970	nucleotide binding site [chemical binding]; other site
511145000971	homodimer interface [polypeptide binding]; other site
511145000972	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
511145000973	cytosine deaminase; Provisional; Region: PRK05985
511145000974	active site
511145000975	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
511145000976	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
511145000977	putative NAD(P) binding site [chemical binding]; other site
511145000978	putative substrate binding site [chemical binding]; other site
511145000979	catalytic Zn binding site [ion binding]; other site
511145000980	structural Zn binding site [ion binding]; other site
511145000981	dimer interface [polypeptide binding]; other site
511145000982	The Resistance to Homoserine/Threonine (RhtB) Family protein; Region: 2A76; TIGR00949
511145000983	hypothetical protein; Provisional; Region: PRK09929
511145000984	propionate catabolism operon regulatory protein PrpR; Provisional; Region: PRK15424
511145000985	Propionate catabolism activator; Region: PrpR_N; pfam06506
511145000986	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145000987	Walker A motif; other site
511145000988	ATP binding site [chemical binding]; other site
511145000989	Walker B motif; other site
511145000990	arginine finger; other site
511145000991	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145000992	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
511145000993	tetramer interface [polypeptide binding]; other site
511145000994	active site
511145000995	Mg2+/Mn2+ binding site [ion binding]; other site
511145000996	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
511145000997	Subgroup of Escherichia coli (Ec) 2-methylcitrate synthase (2MCS)_like. 2MCS catalyzes the condensation of propionyl-coenzyme A (PrCoA) and oxalacetate (OAA) to form 2-methylcitrate and coenzyme A (CoA) during propionate metabolism. Citrate synthase (CS)...; Region: Ec2MCS_like_1; cd06117
511145000998	dimer interface [polypeptide binding]; other site
511145000999	active site
511145001000	citrylCoA binding site [chemical binding]; other site
511145001001	oxalacetate/citrate binding site [chemical binding]; other site
511145001002	coenzyme A binding site [chemical binding]; other site
511145001003	catalytic triad [active]
511145001004	2-methylcitrate dehydratase; Provisional; Region: prpD; PRK09425
511145001005	propionyl-CoA synthetase; Provisional; Region: prpE; PRK10524
511145001006	Propionyl-CoA synthetase (PrpE); Region: PrpE; cd05967
511145001007	acyl-activating enzyme (AAE) consensus motif; other site
511145001008	putative AMP binding site [chemical binding]; other site
511145001009	putative active site [active]
511145001010	putative CoA binding site [chemical binding]; other site
511145001011	nucleobase-cation-symport-1 (NCS1) transporter CobB-like; solute-binding domain; Region: SLC-NCS1sbd_CobB-like; cd11484
511145001012	Na binding site [ion binding]; other site
511145001013	putative substrate binding site [chemical binding]; other site
511145001014	Cytosine deaminase and related metal-dependent hydrolases [Nucleotide transport and metabolism / General function prediction only]; Region: SsnA; COG0402
511145001015	Bacterial cytosine deaminase and related metal-dependent hydrolases. Cytosine deaminases (CDs) catalyze the deamination of cytosine, producing uracil and ammonia. They play an important role in pyrimidine salvage. CDs are present in prokaryotes and fungi; Region: Bact_CD; cd01293
511145001016	active site
511145001017	DNA-binding transcriptional regulator CynR; Provisional; Region: PRK11242
511145001018	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145001019	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator CynR, contains the type 2 periplasmic binding fold; Region: PBP2_CynR; cd08425
511145001020	dimerization interface [polypeptide binding]; other site
511145001021	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeB; cd00884
511145001022	active site clefts [active]
511145001023	zinc binding site [ion binding]; other site
511145001024	dimer interface [polypeptide binding]; other site
511145001025	Cyanate lyase [Inorganic ion transport and metabolism]; Region: CynS; COG1513
511145001026	Cyanase C-terminal domain. Cyanase (Cyanate lyase) is responsible for the hydrolysis of cyanate.  It catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide. This allows organisms that possess the enzyme to overcome the...; Region: Cyanase_C; cd00559
511145001027	oligomer interface [polypeptide binding]; other site
511145001028	active site
511145001029	putative cyanate transporter; Provisional; Region: cynX; PRK09705
511145001030	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001031	putative substrate translocation pore; other site
511145001032	galactoside O-acetyltransferase; Reviewed; Region: lacA; PRK09527
511145001033	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
511145001034	active site
511145001035	substrate binding site [chemical binding]; other site
511145001036	trimer interface [polypeptide binding]; other site
511145001037	CoA binding site [chemical binding]; other site
511145001038	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
511145001039	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001040	putative substrate translocation pore; other site
511145001041	beta-D-galactosidase; Reviewed; Region: lacZ; PRK09525
511145001042	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
511145001043	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
511145001044	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
511145001045	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
511145001046	lac repressor; Reviewed; Region: lacI; PRK09526
511145001047	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145001048	DNA binding site [nucleotide binding]
511145001049	domain linker motif; other site
511145001050	Ligand-binding domain of DNA transcription repressor LacI specific for lactose, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_LacI; cd01574
511145001051	ligand binding site [chemical binding]; other site
511145001052	dimerization interface (open form) [polypeptide binding]; other site
511145001053	dimerization interface (closed form) [polypeptide binding]; other site
511145001054	DNA-binding transcriptional activator MhpR; Provisional; Region: PRK09834
511145001055	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145001056	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145001057	3-(3-hydroxyphenyl)propionate hydroxylase; Validated; Region: mhpA; PRK06183
511145001058	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145001059	Subunit B of the Class III Extradiol ring-cleavage dioxygenase, 2,3-dihydroxyphenylpropionate 1,2-dioxygenase (MhpB), which catalyzes the oxidization and subsequent ring-opening of 2,3-dihydroxyphenylpropionate; Region: MhpB_like; cd07365
511145001060	putative active site [active]
511145001061	Fe(II) binding site [ion binding]; other site
511145001062	putative dimer interface [polypeptide binding]; other site
511145001063	putative tetramer interface [polypeptide binding]; other site
511145001064	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Region: biphenyl_bphD; TIGR03343
511145001065	Putative lysophospholipase; Region: Hydrolase_4; cl19140
511145001066	Uncharacterized conserved protein (DUF2048); Region: DUF2048; pfam09752
511145001067	2-keto-4-pentenoate hydratase; Provisional; Region: mhpD; PRK11342
511145001068	acetaldehyde dehydrogenase; Validated; Region: PRK08300
511145001069	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
511145001070	Prokaryotic acetaldehyde dehydrogenase, dimerization; Region: AcetDehyd-dimer; pfam09290
511145001071	4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase,; Validated; Region: PRK08195
511145001072	4-hydroxy-2-oxovalerate aldolase, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_HOA; cd07943
511145001073	active site
511145001074	catalytic residues [active]
511145001075	metal binding site [ion binding]; metal-binding site
511145001076	DmpG-like communication domain; Region: DmpG_comm; pfam07836
511145001077	putative 3-hydroxyphenylpropionic transporter MhpT; Provisional; Region: PRK11551
511145001078	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001079	putative substrate translocation pore; other site
511145001080	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3122
511145001081	Predicted esterase [General function prediction only]; Region: COG0627
511145001082	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
511145001083	class III alcohol dehydrogenases; Region: alcohol_DH_class_III; cd08300
511145001084	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase; Region: adh_III_F_hyde; TIGR02818
511145001085	substrate binding site [chemical binding]; other site
511145001086	catalytic Zn binding site [ion binding]; other site
511145001087	NAD binding site [chemical binding]; other site
511145001088	structural Zn binding site [ion binding]; other site
511145001089	dimer interface [polypeptide binding]; other site
511145001090	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
511145001091	putative metal binding site [ion binding]; other site
511145001092	putative homodimer interface [polypeptide binding]; other site
511145001093	putative homotetramer interface [polypeptide binding]; other site
511145001094	putative homodimer-homodimer interface [polypeptide binding]; other site
511145001095	putative allosteric switch controlling residues; other site
511145001096	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145001097	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145001098	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145001099	HTH-like domain; Region: HTH_21; pfam13276
511145001100	Integrase core domain; Region: rve; pfam00665
511145001101	Integrase core domain; Region: rve_3; pfam13683
511145001102	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
511145001103	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
511145001104	DXD motif; other site
511145001105	Uncharacterized proteins, LmbE homologs [Function unknown]; Region: COG2120
511145001106	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
511145001107	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145001108	substrate binding pocket [chemical binding]; other site
511145001109	membrane-bound complex binding site; other site
511145001110	hinge residues; other site
511145001111	taurine transporter ATP-binding subunit; Provisional; Region: tauB; PRK11248
511145001112	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
511145001113	Walker A/P-loop; other site
511145001114	ATP binding site [chemical binding]; other site
511145001115	Q-loop/lid; other site
511145001116	ABC transporter signature motif; other site
511145001117	Walker B; other site
511145001118	D-loop; other site
511145001119	H-loop/switch region; other site
511145001120	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
511145001121	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145001122	dimer interface [polypeptide binding]; other site
511145001123	conserved gate region; other site
511145001124	putative PBP binding loops; other site
511145001125	ABC-ATPase subunit interface; other site
511145001126	Probable taurine catabolism dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: TauD; COG2175
511145001127	taurine dioxygenase; Reviewed; Region: tauD; PRK09553
511145001128	active site
511145001129	iron coordination sites [ion binding]; other site
511145001130	substrate binding pocket [chemical binding]; other site
511145001131	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
511145001132	dimer interface [polypeptide binding]; other site
511145001133	active site
511145001134	Schiff base residues; other site
511145001135	putative transposase OrfB; Reviewed; Region: PHA02517
511145001136	HTH-like domain; Region: HTH_21; pfam13276
511145001137	Integrase core domain; Region: rve; pfam00665
511145001138	Integrase core domain; Region: rve_2; pfam13333
511145001139	Transposase; Region: HTH_Tnp_1; cl17663
511145001140	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145001141	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11832
511145001142	beta-lactam binding protein AmpH; Provisional; Region: PRK10662
511145001143	microcin B17 transporter; Reviewed; Region: PRK11098
511145001144	Protein of unknown function (DUF1615); Region: DUF1615; pfam07759
511145001145	Protein of unknown function (DUF2755); Region: DUF2755; pfam10954
511145001146	Protein of unknown function (DUF2754); Region: DUF2754; pfam10953
511145001147	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
511145001148	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
511145001149	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
511145001150	anti-RssB factor; Provisional; Region: PRK10244
511145001151	Alkaline phosphatase [Inorganic ion transport and metabolism]; Region: PhoA; COG1785
511145001152	Alkaline phosphatase homologues; alkaline phosphatases are non-specific phosphomonoesterases that catalyze the hydrolysis reaction via a phosphoseryl intermediate to produce inorganic phosphate and the corresponding alcohol, optimally at high pH; Region: alkPPc; cd00016
511145001153	dimer interface [polypeptide binding]; other site
511145001154	active site
511145001155	hypothetical protein; Provisional; Region: PRK11505
511145001156	psiF repeat; Region: PsiF_repeat; pfam07769
511145001157	psiF repeat; Region: PsiF_repeat; pfam07769
511145001158	diguanylate cyclase AdrA; Provisional; Region: adrA; PRK10245
511145001159	MASE2 domain; Region: MASE2; pfam05230
511145001160	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145001161	metal binding site [ion binding]; metal-binding site
511145001162	active site
511145001163	I-site; other site
511145001164	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
511145001165	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
511145001166	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
511145001167	hypothetical protein; Validated; Region: PRK00124
511145001168	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
511145001169	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
511145001170	ADP binding site [chemical binding]; other site
511145001171	magnesium binding site [ion binding]; other site
511145001172	putative shikimate binding site; other site
511145001173	hypothetical protein; Provisional; Region: PRK10380
511145001174	hypothetical protein; Provisional; Region: PRK10481
511145001175	hypothetical protein; Provisional; Region: PRK10579
511145001176	DNA recombination-dependent growth factor C [DNA replication, recombination, and repair]; Region: RdgC; COG2974
511145001177	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145001178	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145001179	nucleotide binding site [chemical binding]; other site
511145001180	MFS transport protein AraJ; Provisional; Region: PRK10091
511145001181	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001182	putative substrate translocation pore; other site
511145001183	exonuclease subunit SbcC; Provisional; Region: PRK10246
511145001184	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145001185	Walker A/P-loop; other site
511145001186	ATP binding site [chemical binding]; other site
511145001187	Q-loop/lid; other site
511145001188	HemX; Region: HemX; cl19375
511145001189	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145001190	ABC transporter signature motif; other site
511145001191	Walker B; other site
511145001192	D-loop; other site
511145001193	H-loop/switch region; other site
511145001194	exonuclease subunit SbcD; Provisional; Region: PRK10966
511145001195	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
511145001196	active site
511145001197	metal binding site [ion binding]; metal-binding site
511145001198	DNA binding site [nucleotide binding]
511145001199	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
511145001200	transcriptional regulator PhoB; Provisional; Region: PRK10161
511145001201	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145001202	active site
511145001203	phosphorylation site [posttranslational modification]
511145001204	intermolecular recognition site; other site
511145001205	dimerization interface [polypeptide binding]; other site
511145001206	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145001207	DNA binding site [nucleotide binding]
511145001208	phosphate regulon sensor protein; Provisional; Region: phoR; PRK11006
511145001209	Domain of unknown function (DUF3329); Region: DUF3329; pfam11808
511145001210	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145001211	putative active site [active]
511145001212	heme pocket [chemical binding]; other site
511145001213	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145001214	dimer interface [polypeptide binding]; other site
511145001215	phosphorylation site [posttranslational modification]
511145001216	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145001217	ATP binding site [chemical binding]; other site
511145001218	Mg2+ binding site [ion binding]; other site
511145001219	G-X-G motif; other site
511145001220	branched-chain amino acid transport system 2 carrier protein BrnQ; Provisional; Region: PRK15433
511145001221	putative proline-specific permease; Provisional; Region: proY; PRK10580
511145001222	Spore germination protein; Region: Spore_permease; cl17796
511145001223	maltodextrin glucosidase; Provisional; Region: PRK10785
511145001224	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
511145001225	homodimer interface [polypeptide binding]; other site
511145001226	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
511145001227	active site
511145001228	homodimer interface [polypeptide binding]; other site
511145001229	catalytic site [active]
511145001230	acyl carrier protein phosphodiesterase; Provisional; Region: PRK10045
511145001231	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
511145001232	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
511145001233	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
511145001234	preprotein translocase subunit YajC; Validated; Region: yajC; PRK05585
511145001235	SecD export protein N-terminal TM region; Region: SecD-TM1; pfam13721
511145001236	preprotein translocase subunit SecD; Reviewed; Region: secD; PRK05812
511145001237	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
511145001238	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
511145001239	preprotein translocase subunit SecF; Reviewed; Region: secF; PRK13022
511145001240	SecD/SecF GG Motif; Region: Sec_GG; pfam07549
511145001241	Protein export membrane protein; Region: SecD_SecF; pfam02355
511145001242	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
511145001243	active site
511145001244	nucleoside-specific channel-forming protein Tsx; Provisional; Region: PRK15106
511145001245	hypothetical protein; Provisional; Region: PRK11530
511145001246	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
511145001247	ATP cone domain; Region: ATP-cone; pfam03477
511145001248	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase; Provisional; Region: ribD; PRK10786
511145001249	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
511145001250	catalytic motif [active]
511145001251	Zn binding site [ion binding]; other site
511145001252	riboflavin-specific deaminase C-terminal domain; Region: ribD_Cterm; TIGR00227
511145001253	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
511145001254	homopentamer interface [polypeptide binding]; other site
511145001255	active site
511145001256	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
511145001257	thiamine monophosphate kinase; Provisional; Region: PRK05731
511145001258	ThiL (Thiamine-monophosphate kinase) plays a dual role in de novo biosynthesis and in salvage of exogenous thiamine. Thiamine salvage occurs in two steps, with thiamine kinase catalyzing the formation of thiamine phosphate, and ThiL catalyzing the...; Region: ThiL; cd02194
511145001259	ATP binding site [chemical binding]; other site
511145001260	dimerization interface [polypeptide binding]; other site
511145001261	Phosphatidylglycerophosphatase A; a bacterial membrane-associated enzyme involved in lipid metabolism; Region: PgpA; cd06971
511145001262	tetramer interfaces [polypeptide binding]; other site
511145001263	binuclear metal-binding site [ion binding]; other site
511145001264	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145001265	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145001266	active site
511145001267	catalytic tetrad [active]
511145001268	1-deoxy-D-xylulose-5-phosphate synthase; Region: dxs; TIGR00204
511145001269	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
511145001270	TPP-binding site; other site
511145001271	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
511145001272	PYR/PP interface [polypeptide binding]; other site
511145001273	dimer interface [polypeptide binding]; other site
511145001274	TPP binding site [chemical binding]; other site
511145001275	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
511145001276	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
511145001277	substrate binding pocket [chemical binding]; other site
511145001278	chain length determination region; other site
511145001279	active site lid residues [active]
511145001280	substrate-Mg2+ binding site; other site
511145001281	catalytic residues [active]
511145001282	aspartate-rich region 1; other site
511145001283	aspartate-rich region 2; other site
511145001284	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
511145001285	tRNA s(4)U8 sulfurtransferase; Provisional; Region: PRK01269
511145001286	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
511145001287	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
511145001288	Ligand Binding Site [chemical binding]; other site
511145001289	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
511145001290	active site residue [active]
511145001291	oxidative-stress-resistance chaperone; Provisional; Region: PRK11574
511145001292	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
511145001293	conserved cys residue [active]
511145001294	2-dehydropantoate 2-reductase; Reviewed; Region: PRK06522
511145001295	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
511145001296	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
511145001297	Proteins similar to Escherichia coli YajQ; Region: YajQ_like; cd11740
511145001298	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001299	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145001300	putative substrate translocation pore; other site
511145001301	Protoheme IX farnesyltransferase; Region: PT_UbiA_Cox10; cd13957
511145001302	putative active site [active]
511145001303	cytochrome o ubiquinol oxidase subunit IV; Provisional; Region: PRK10582
511145001304	Ubiquinol oxidase subunit III subfamily. Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously...; Region: Ubiquinol_oxidase_III; cd02863
511145001305	Subunit I/III interface [polypeptide binding]; other site
511145001306	Subunit III/IV interface [polypeptide binding]; other site
511145001307	Heme/copper-type cytochrome/quinol oxidases, subunit 1 [Energy production and conversion]; Region: CyoB; COG0843
511145001308	Ubiquinol oxidase subunit I.  Ubiquinol oxidase, the terminal oxidase in the respiratory chains of aerobic bacteria, is a multi-chain transmembrane protein located in the cell membrane.  It catalyzes the reduction of O2 and simultaneously pumps protons...; Region: Ubiquinol_Oxidase_I; cd01662
511145001309	D-pathway; other site
511145001310	Putative ubiquinol binding site [chemical binding]; other site
511145001311	Low-spin heme (heme b) binding site [chemical binding]; other site
511145001312	Putative water exit pathway; other site
511145001313	Binuclear center (heme o3/CuB) [ion binding]; other site
511145001314	K-pathway; other site
511145001315	Putative proton exit pathway; other site
511145001316	cytochrome o ubiquinol oxidase subunit II; Provisional; Region: PRK10525
511145001317	The cupredoxin domain of Ubiquinol oxidase subunit II; Region: CuRO_UO_II; cd04212
511145001318	COX Aromatic Rich Motif; Region: COX_ARM; pfam06481
511145001319	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001320	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145001321	putative substrate translocation pore; other site
511145001322	hypothetical protein; Provisional; Region: PRK11627
511145001323	transcriptional regulator BolA; Provisional; Region: PRK11628
511145001324	trigger factor; Provisional; Region: tig; PRK01490
511145001325	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
511145001326	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
511145001327	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
511145001328	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
511145001329	oligomer interface [polypeptide binding]; other site
511145001330	active site residues [active]
511145001331	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
511145001332	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
511145001333	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145001334	Walker A motif; other site
511145001335	ATP binding site [chemical binding]; other site
511145001336	Walker B motif; other site
511145001337	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
511145001338	DNA-binding ATP-dependent protease La; Provisional; Region: PRK10787
511145001339	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
511145001340	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145001341	Walker A motif; other site
511145001342	ATP binding site [chemical binding]; other site
511145001343	Walker B motif; other site
511145001344	arginine finger; other site
511145001345	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
511145001346	histone-like DNA-binding protein HU; Region: HU; cd13831
511145001347	dimer interface [polypeptide binding]; other site
511145001348	DNA binding site [nucleotide binding]
511145001349	periplasmic folding chaperone; Provisional; Region: PRK10788
511145001350	SurA N-terminal domain; Region: SurA_N_3; cl07813
511145001351	PPIC-type PPIASE domain; Region: Rotamase_2; pfam13145
511145001352	DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair]; Region: ComEA; COG1555
511145001353	Bacterial cellulose synthase subunit; Region: BcsB; cl15851
511145001354	competence protein ComEA helix-hairpin-helix repeat region; Region: TIGR00426
511145001355	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
511145001356	active site
511145001357	ExsB is a transcription regulator related protein. It is a subfamily of a Adenosine nucleotide binding superfamily of proteins. This protein family is represented by a single member in nearly every completed large (> 1000 genes) prokaryotic genome. In...; Region: ExsB; cd01995
511145001358	Ligand Binding Site [chemical binding]; other site
511145001359	ABC-type uncharacterized transport system, periplasmic component [General function prediction only]; Region: COG4533
511145001360	Sugar transport-related sRNA regulator N-term; Region: SgrR_N; pfam12793
511145001361	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
511145001362	thiamin pyrimidine pyrophosphate hydrolase; Provisional; Region: PRK15126
511145001363	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145001364	active site
511145001365	motif I; other site
511145001366	motif II; other site
511145001367	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145001368	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
511145001369	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145001370	putative DNA binding site [nucleotide binding]; other site
511145001371	putative Zn2+ binding site [ion binding]; other site
511145001372	AsnC family; Region: AsnC_trans_reg; pfam01037
511145001373	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145001374	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10789
511145001375	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145001376	Walker A/P-loop; other site
511145001377	ATP binding site [chemical binding]; other site
511145001378	Q-loop/lid; other site
511145001379	ABC transporter signature motif; other site
511145001380	Walker B; other site
511145001381	D-loop; other site
511145001382	H-loop/switch region; other site
511145001383	putative multidrug transporter membrane\ATP-binding components; Provisional; Region: PRK10790
511145001384	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145001385	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145001386	Walker A/P-loop; other site
511145001387	ATP binding site [chemical binding]; other site
511145001388	Q-loop/lid; other site
511145001389	ABC transporter signature motif; other site
511145001390	Walker B; other site
511145001391	D-loop; other site
511145001392	H-loop/switch region; other site
511145001393	nitrogen regulatory protein P-II 2; Provisional; Region: PRK10665
511145001394	ammonium transporter; Provisional; Region: PRK10666
511145001395	acyl-CoA thioesterase II; Provisional; Region: PRK10526
511145001396	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat2; cd03445
511145001397	active site
511145001398	Thioesterase II (TEII) is thought to regenerate misprimed nonribosomal peptide synthetases (NRPSs) as well as modular polyketide synthases (PKSs) by hydrolyzing acetyl groups bound to the peptidyl carrier protein (PCP) and acyl carrier protein (ACP)...; Region: Thioesterase_II_repeat1; cd03444
511145001399	catalytic triad [active]
511145001400	dimer interface [polypeptide binding]; other site
511145001401	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3126
511145001402	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
511145001403	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
511145001404	DNA binding site [nucleotide binding]
511145001405	active site
511145001406	Uncharacterized conserved protein [Function unknown]; Region: COG5507
511145001407	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
511145001408	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
511145001409	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145001410	Inner membrane protein YlaC; Region: YlaC; pfam10777
511145001411	maltose O-acetyltransferase; Provisional; Region: PRK10092
511145001412	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
511145001413	active site
511145001414	substrate binding site [chemical binding]; other site
511145001415	trimer interface [polypeptide binding]; other site
511145001416	CoA binding site [chemical binding]; other site
511145001417	gene expression modulator; Provisional; Region: PRK10945
511145001418	Biofilm formation regulator YbaJ; Region: YbaJ; pfam10757
511145001419	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
511145001420	MMPL family; Region: MMPL; cl14618
511145001421	MMPL family; Region: MMPL; cl14618
511145001422	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
511145001423	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
511145001424	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145001425	DNA-binding transcriptional repressor AcrR; Provisional; Region: PRK10668
511145001426	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145001427	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
511145001428	hypothetical protein; Provisional; Region: PRK11281
511145001429	FSIP1 family; Region: FSIP1; pfam15554
511145001430	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
511145001431	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145001432	hypothetical protein; Provisional; Region: PRK11038
511145001433	primosomal replication protein N''; Provisional; Region: PRK10093
511145001434	hypothetical protein; Provisional; Region: PRK10527
511145001435	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145001436	active site
511145001437	DNA polymerase III subunits gamma and tau; Validated; Region: PRK07994
511145001438	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145001439	Walker A motif; other site
511145001440	ATP binding site [chemical binding]; other site
511145001441	Walker B motif; other site
511145001442	DNA polymerase III subunit delta'; Validated; Region: PRK08485
511145001443	arginine finger; other site
511145001444	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
511145001445	DNA polymerase III subunits tau domain IV DnaB-binding; Region: DNA_pol3_tau_4; pfam12168
511145001446	DNA polymerase III tau subunit V interacting with alpha; Region: DNA_pol3_tau_5; pfam12170
511145001447	hypothetical protein; Validated; Region: PRK00153
511145001448	recombination protein RecR; Reviewed; Region: recR; PRK00076
511145001449	RecR protein; Region: RecR; pfam02132
511145001450	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
511145001451	putative active site [active]
511145001452	putative metal-binding site [ion binding]; other site
511145001453	tetramer interface [polypeptide binding]; other site
511145001454	heat shock protein 90; Provisional; Region: PRK05218
511145001455	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145001456	ATP binding site [chemical binding]; other site
511145001457	Mg2+ binding site [ion binding]; other site
511145001458	G-X-G motif; other site
511145001459	Hsp90 protein; Region: HSP90; pfam00183
511145001460	adenylate kinase; Reviewed; Region: adk; PRK00279
511145001461	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
511145001462	AMP-binding site [chemical binding]; other site
511145001463	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
511145001464	ferrochelatase; Region: hemH; TIGR00109
511145001465	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
511145001466	C-terminal domain interface [polypeptide binding]; other site
511145001467	active site
511145001468	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
511145001469	active site
511145001470	N-terminal domain interface [polypeptide binding]; other site
511145001471	acetyl esterase; Provisional; Region: PRK10162
511145001472	Esterase/lipase [Lipid metabolism]; Region: Aes; COG0657
511145001473	inosine/guanosine kinase; Provisional; Region: PRK15074
511145001474	adenosine kinase; Provisional; Region: PTZ00247
511145001475	substrate binding site [chemical binding]; other site
511145001476	ATP binding site [chemical binding]; other site
511145001477	putative cation:proton antiport protein; Provisional; Region: PRK10669
511145001478	Kef-type K+ transport system, predicted NAD-binding component [Inorganic ion transport and metabolism]; Region: RosB; COG4651
511145001479	TrkA-N domain; Region: TrkA_N; pfam02254
511145001480	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001481	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145001482	putative substrate translocation pore; other site
511145001483	bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed; Region: ushA; PRK09558
511145001484	Escherichia coli UshA and related proteins, N-terminal metallophosphatase domain; Region: MPP_UshA_N; cd07405
511145001485	active site
511145001486	metal binding site [ion binding]; metal-binding site
511145001487	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
511145001488	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
511145001489	putative deacylase active site [active]
511145001490	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3735
511145001491	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145001492	non-specific DNA binding site [nucleotide binding]; other site
511145001493	salt bridge; other site
511145001494	sequence-specific DNA binding site [nucleotide binding]; other site
511145001495	copper exporting ATPase; Provisional; Region: copA; PRK10671
511145001496	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
511145001497	metal-binding site [ion binding]
511145001498	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
511145001499	metal-binding site [ion binding]
511145001500	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
511145001501	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145001502	motif II; other site
511145001503	glutaminase; Reviewed; Region: PRK12356
511145001504	amino acid transporter; Region: 2A0306; TIGR00909
511145001505	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
511145001506	DNA-binding transcriptional regulator CueR; Provisional; Region: PRK10227
511145001507	Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators; Region: HTH_CueR; cd01108
511145001508	DNA binding residues [nucleotide binding]
511145001509	dimer interface [polypeptide binding]; other site
511145001510	copper binding site [ion binding]; other site
511145001511	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
511145001512	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
511145001513	Paraslipin or slipin-2 (SLP-2, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_paraslipin; cd08829
511145001514	putative ABC transporter ATP-binding protein YbbL; Provisional; Region: PRK10247
511145001515	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145001516	Walker A/P-loop; other site
511145001517	ATP binding site [chemical binding]; other site
511145001518	Q-loop/lid; other site
511145001519	ABC transporter signature motif; other site
511145001520	Walker B; other site
511145001521	D-loop; other site
511145001522	H-loop/switch region; other site
511145001523	TIGR00245 family protein; Region: TIGR00245
511145001524	Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones]; Region: COG3118
511145001525	ybbN protein family; ybbN is a hypothetical protein containing a redox-inactive TRX-like domain. Its gene has been sequenced from several gammaproteobacteria and actinobacteria; Region: ybbN; cd02956
511145001526	Tetratricopeptide repeat; Region: TPR_20; pfam14561
511145001527	short chain dehydrogenase; Validated; Region: PRK06182
511145001528	17beta hydroxysteroid dehydrogenase-like, classical (c) SDRs; Region: 17beta-HSD-like_SDR_c; cd05374
511145001529	NADP binding site [chemical binding]; other site
511145001530	active site
511145001531	steroid binding site; other site
511145001532	Lysophospholipase L1-like subgroup of SGNH-hydrolases. The best characterized member in this family is TesA, an E. coli periplasmic protein with thioesterase, esterase, arylesterase, protease and lysophospholipase activity; Region: Lysophospholipase_L1_like; cd01822
511145001533	active site
511145001534	catalytic triad [active]
511145001535	oxyanion hole [active]
511145001536	switch loop; other site
511145001537	putative ABC transporter ATP-binding protein YbbA; Provisional; Region: PRK10584
511145001538	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
511145001539	Walker A/P-loop; other site
511145001540	ATP binding site [chemical binding]; other site
511145001541	Q-loop/lid; other site
511145001542	ABC transporter signature motif; other site
511145001543	Walker B; other site
511145001544	D-loop; other site
511145001545	H-loop/switch region; other site
511145001546	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3127
511145001547	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
511145001548	FtsX-like permease family; Region: FtsX; pfam02687
511145001549	FtsX-like permease family; Region: FtsX; pfam02687
511145001550	PAAR motif; Region: PAAR_motif; cl15808
511145001551	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145001552	RHS Repeat; Region: RHS_repeat; pfam05593
511145001553	RHS Repeat; Region: RHS_repeat; pfam05593
511145001554	RHS Repeat; Region: RHS_repeat; pfam05593
511145001555	RHS Repeat; Region: RHS_repeat; pfam05593
511145001556	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145001557	RHS Repeat; Region: RHS_repeat; pfam05593
511145001558	YD repeat (two copies); Region: YD_repeat_2x; TIGR01643
511145001559	RHS Repeat; Region: RHS_repeat; pfam05593
511145001560	Erythromycin esterase; Region: Erythro_esteras; cl17110
511145001561	RHS protein; Region: RHS; pfam03527
511145001562	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
511145001563	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
511145001564	NTF2 fold immunity protein; Region: Imm-NTF2-2; pfam15631
511145001565	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
511145001566	Member of the Rhodanese Homology Domain superfamily. This CD includes several putative ATP /GTP binding proteins including E. coli YbbB; Region: RHOD_YbbB; cd01520
511145001567	active site residue [active]
511145001568	DNA-binding transcriptional activator AllS; Provisional; Region: PRK10094
511145001569	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145001570	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145001571	dimerization interface [polypeptide binding]; other site
511145001572	Ureidoglycolate hydrolase [Nucleotide transport and metabolism]; Region: DAL3; COG3194
511145001573	DNA-binding transcriptional repressor AllR; Provisional; Region: PRK10163
511145001574	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145001575	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145001576	glyoxylate carboligase; Provisional; Region: PRK11269
511145001577	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
511145001578	PYR/PP interface [polypeptide binding]; other site
511145001579	dimer interface [polypeptide binding]; other site
511145001580	TPP binding site [chemical binding]; other site
511145001581	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
511145001582	Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the...; Region: TPP_Gcl; cd02006
511145001583	TPP-binding site [chemical binding]; other site
511145001584	hydroxypyruvate isomerase; Provisional; Region: PRK09997
511145001585	hydroxypyruvate isomerase; Region: OH-pyruv-isom; TIGR03234
511145001586	tartronate semialdehyde reductase; Provisional; Region: PRK15059
511145001587	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
511145001588	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
511145001589	nucleobase-cation-symport-1 (NCS1) transporters; solute-binding domain; Region: SLC-NCS1sbd; cd10323
511145001590	Na binding site [ion binding]; other site
511145001591	substrate binding site [chemical binding]; other site
511145001592	allantoinase; Provisional; Region: PRK08044
511145001593	L-Hydantoinases (L-HYDs) and Allantoinase (ALN); L-Hydantoinases are a member of the dihydropyrimidinase family, which catalyzes the reversible hydrolytic ring opening of dihydropyrimidines and hydantoins (five-membered cyclic diamides used in...; Region: L-HYD_ALN; cd01315
511145001594	active site
511145001595	putative uracil/xanthine transporter; Provisional; Region: PRK11412
511145001596	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
511145001597	glycerate kinase II; Provisional; Region: PRK09932
511145001598	Uncharacterized protein, possibly involved in glyoxylate utilization [General function prediction only]; Region: GlxB; COG3257
511145001599	Protein of unknown function (DUF861); Region: Cupin_3; pfam05899
511145001600	Cupin domain; Region: Cupin_2; cl17218
511145001601	allantoate amidohydrolase; Region: AllC; TIGR03176
511145001602	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
511145001603	active site
511145001604	metal binding site [ion binding]; metal-binding site
511145001605	dimer interface [polypeptide binding]; other site
511145001606	ureidoglycolate dehydrogenase; Provisional; Region: PRK15025
511145001607	membrane protein FdrA; Validated; Region: PRK06091
511145001608	CoA binding domain; Region: CoA_binding; pfam02629
511145001609	CoA-ligase; Region: Ligase_CoA; pfam00549
511145001610	Protein of unknown function (DUF2877); Region: DUF2877; pfam11392
511145001611	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
511145001612	putative substrate binding site [chemical binding]; other site
511145001613	nucleotide binding site [chemical binding]; other site
511145001614	nucleotide binding site [chemical binding]; other site
511145001615	homodimer interface [polypeptide binding]; other site
511145001616	Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) [Nucleotide transport and metabolism]; Region: PurK; COG0026
511145001617	ATP-grasp domain; Region: ATP-grasp; pfam02222
511145001618	Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase [Nucleotide transport and metabolism]; Region: PurE; COG0041
511145001619	Escherichia coli YbbF/LpxH and related proteins, metallophosphatase domain; Region: MPP_YbbF-LpxH; cd07398
511145001620	putative active site [active]
511145001621	putative metal binding site [ion binding]; other site
511145001622	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
511145001623	substrate binding site [chemical binding]; other site
511145001624	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
511145001625	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
511145001626	active site
511145001627	HIGH motif; other site
511145001628	KMSKS motif; other site
511145001629	Anticodon-binding domain of cysteinyl tRNA synthetases; Region: Anticodon_Ia_Cys; cd07963
511145001630	tRNA binding surface [nucleotide binding]; other site
511145001631	anticodon binding site; other site
511145001632	Predicted membrane-bound metal-dependent hydrolases [General function prediction only]; Region: COG1988
511145001633	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145001634	RNA binding surface [nucleotide binding]; other site
511145001635	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK10792
511145001636	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
511145001637	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
511145001638	homodimer interface [polypeptide binding]; other site
511145001639	NADP binding site [chemical binding]; other site
511145001640	substrate binding site [chemical binding]; other site
511145001641	type-1 fimbrial protein subunit A; Provisional; Region: PRK15194
511145001642	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
511145001643	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145001644	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145001645	outer membrane usher protein FimD; Provisional; Region: PRK15198
511145001646	PapC N-terminal domain; Region: PapC_N; pfam13954
511145001647	Outer membrane usher protein; Region: Usher; pfam00577
511145001648	PapC C-terminal domain; Region: PapC_C; pfam13953
511145001649	fimbrial-like adhesin; Provisional; Region: fimH; PRK15199
511145001650	fimbrial-like adhesin protein SfmF; Provisional; Region: PRK09934
511145001651	transcriptional regulator FimZ; Provisional; Region: PRK09935
511145001652	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145001653	active site
511145001654	phosphorylation site [posttranslational modification]
511145001655	intermolecular recognition site; other site
511145001656	dimerization interface [polypeptide binding]; other site
511145001657	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145001658	DNA binding residues [nucleotide binding]
511145001659	dimerization interface [polypeptide binding]; other site
511145001660	cryptic prophage DLP12
511145001661	integrase; Provisional; Region: int; PHA02601
511145001662	P22-like integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial and phage integrases, including those similar to phage P22-like integrases, DLP12 and APSE-1; Region: INT_P22_C; cd01192
511145001663	Int/Topo IB signature motif; other site
511145001664	Transposase; Region: HTH_Tnp_1; cl17663
511145001665	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145001666	putative transposase OrfB; Reviewed; Region: PHA02517
511145001667	HTH-like domain; Region: HTH_21; pfam13276
511145001668	Integrase core domain; Region: rve; pfam00665
511145001669	Integrase core domain; Region: rve_2; pfam13333
511145001670	multidrug efflux protein; Reviewed; Region: emrE; PRK09541
511145001671	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
511145001672	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
511145001673	catalytic residues [active]
511145001674	catalytic nucleophile [active]
511145001675	Recombinase; Region: Recombinase; pfam07508
511145001676	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
511145001677	Defensin propeptide; Region: Defensin_propep; pfam00879
511145001678	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
511145001679	substrate binding site [chemical binding]; other site
511145001680	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145001681	hypothetical protein; Provisional; Region: PRK09741
511145001682	prophage protein NinE; Provisional; Region: PRK09689
511145001683	Protein of unknown function (DUF1364); Region: DUF1364; pfam07102
511145001684	endodeoxyribonuclease RUS; Reviewed; Region: PRK09786
511145001685	Phage antitermination protein Q; Region: Phage_antitermQ; pfam06530
511145001686	Transposase domain (DUF772); Region: DUF772; pfam05598
511145001687	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145001688	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145001689	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145001690	Lysis protein S; Region: Lysis_S; pfam04971
511145001691	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
511145001692	catalytic residues [active]
511145001693	Bacteriophage Rz lysis protein; Region: Phage_lysis; pfam03245
511145001694	Lipoprotein Rz1 precursor; Region: Rz1; pfam06085
511145001695	Bor protein; Region: Lambda_Bor; pfam06291
511145001696	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
511145001697	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
511145001698	Phage DNA packaging protein Nu1; Region: Phage_Nu1; pfam07471
511145001699	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145001700	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145001701	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145001702	outer membrane protease; Reviewed; Region: PRK10993
511145001703	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
511145001704	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145001705	hypothetical protein; Provisional; Region: PRK09936
511145001706	bacteriophage N4 receptor, outer membrane subunit; Provisional; Region: PRK09782
511145001707	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145001708	TPR motif; other site
511145001709	binding surface
511145001710	Bacteriophage N adsorption protein A C-term; Region: NfrA_C; pfam13283
511145001711	bacteriophage N4 adsorption protein B; Provisional; Region: PRK14716
511145001712	bacteriophage N4 adsorption protein B; Provisional; Region: nfrB; PRK11234
511145001713	active site
511145001714	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
511145001715	sensor kinase CusS; Provisional; Region: PRK09835
511145001716	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145001717	dimerization interface [polypeptide binding]; other site
511145001718	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145001719	dimer interface [polypeptide binding]; other site
511145001720	phosphorylation site [posttranslational modification]
511145001721	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145001722	ATP binding site [chemical binding]; other site
511145001723	Mg2+ binding site [ion binding]; other site
511145001724	G-X-G motif; other site
511145001725	DNA-binding transcriptional activator CusR; Provisional; Region: PRK09836
511145001726	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145001727	active site
511145001728	phosphorylation site [posttranslational modification]
511145001729	intermolecular recognition site; other site
511145001730	dimerization interface [polypeptide binding]; other site
511145001731	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145001732	DNA binding site [nucleotide binding]
511145001733	copper/silver efflux system outer membrane protein CusC; Provisional; Region: PRK09837
511145001734	Outer membrane efflux protein; Region: OEP; pfam02321
511145001735	Outer membrane efflux protein; Region: OEP; pfam02321
511145001736	periplasmic copper-binding protein; Provisional; Region: PRK09838
511145001737	copper/silver efflux system membrane fusion protein CusB; Provisional; Region: PRK09783
511145001738	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145001739	heavy metal efflux pump, CzcA family; Region: 2A0601; TIGR00914
511145001740	phenylalanine transporter; Provisional; Region: PRK10249
511145001741	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145001742	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
511145001743	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145001744	NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family...; Region: NfsB_like_nitroreductase; cd02149
511145001745	dimer interface [polypeptide binding]; other site
511145001746	FMN binding site [chemical binding]; other site
511145001747	hypothetical protein; Provisional; Region: PRK10250
511145001748	Protein of unknown function (DUF1158); Region: DUF1158; pfam06643
511145001749	gamma-glutamyl:cysteine ligase; Provisional; Region: PRK13516
511145001750	Hok/gef family; Region: HOK_GEF; pfam01848
511145001751	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
511145001752	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145001753	phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Provisional; Region: PRK10251
511145001754	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
511145001755	outer membrane receptor FepA; Provisional; Region: PRK13524
511145001756	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145001757	N-terminal plug; other site
511145001758	ligand-binding site [chemical binding]; other site
511145001759	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3251
511145001760	enterobactin synthase subunit F; Provisional; Region: entF; PRK10252
511145001761	Condensation domain; Region: Condensation; pfam00668
511145001762	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
511145001763	acyl-activating enzyme (AAE) consensus motif; other site
511145001764	AMP binding site [chemical binding]; other site
511145001765	Phosphopantetheine attachment site; Region: PP-binding; pfam00550
511145001766	Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3319
511145001767	LPS O-antigen length regulator; Provisional; Region: PRK10381
511145001768	Chain length determinant protein; Region: Wzz; pfam02706
511145001769	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145001770	iron-enterobactin transporter ATP-binding protein; Provisional; Region: PRK10253
511145001771	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
511145001772	Walker A/P-loop; other site
511145001773	ATP binding site [chemical binding]; other site
511145001774	Q-loop/lid; other site
511145001775	ABC transporter signature motif; other site
511145001776	Walker B; other site
511145001777	D-loop; other site
511145001778	H-loop/switch region; other site
511145001779	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145001780	ABC-ATPase subunit  interface; other site
511145001781	dimer interface [polypeptide binding]; other site
511145001782	putative PBP binding regions; other site
511145001783	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145001784	ABC-ATPase subunit  interface; other site
511145001785	dimer interface [polypeptide binding]; other site
511145001786	putative PBP binding regions; other site
511145001787	enterobactin exporter EntS; Provisional; Region: PRK10489
511145001788	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145001789	putative substrate translocation pore; other site
511145001790	ABC-type Fe2+-enterobactin transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG4592
511145001791	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
511145001792	siderophore binding site; other site
511145001793	isochorismate synthase EntC; Provisional; Region: PRK15016
511145001794	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
511145001795	enterobactin synthase subunit E; Provisional; Region: entE; PRK10946
511145001796	2,3-dihydroxybenzoate-AMP ligase; Region: 23DHB-AMP_lg; cd05920
511145001797	acyl-activating enzyme (AAE) consensus motif; other site
511145001798	active site
511145001799	AMP binding site [chemical binding]; other site
511145001800	substrate binding site [chemical binding]; other site
511145001801	Isochorismatase, also known as 2,3 dihydro-2,3 dihydroxybenzoate synthase, catalyses the conversion of isochorismate, in the presence of water, to 2,3-dihydroxybenzoate and pyruvate, via the hydrolysis of a vinyl ether, an uncommon reaction in biological...; Region: isochorismatase; cd01013
511145001802	hydrophobic substrate binding pocket; other site
511145001803	active site
511145001804	conserved cis-peptide bond; other site
511145001805	Aryl carrier domain [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3433
511145001806	2,3-dihydroxybenzoate-2,3-dehydrogenase; Validated; Region: PRK08220
511145001807	2,3 dihydro-2,3 dihydrozybenzoate dehydrogenases, classical (c) SDRs; Region: DH-DHB-DH_SDR_c; cd05331
511145001808	putative NAD(P) binding site [chemical binding]; other site
511145001809	active site
511145001810	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
511145001811	CoenzymeA binding site [chemical binding]; other site
511145001812	subunit interaction site [polypeptide binding]; other site
511145001813	PHB binding site; other site
511145001814	carbon starvation protein A; Provisional; Region: PRK15015
511145001815	Carbon starvation protein CstA; Region: CstA; pfam02554
511145001816	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
511145001817	Uncharacterized small protein [Function unknown]; Region: COG2879
511145001818	Glycerol dehydrogenases-like; Region: GlyDH-like1; cd08172
511145001819	putative active site [active]
511145001820	metal binding site [ion binding]; metal-binding site
511145001821	methionine aminotransferase; Validated; Region: PRK09082
511145001822	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145001823	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145001824	homodimer interface [polypeptide binding]; other site
511145001825	catalytic residue [active]
511145001826	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
511145001827	ParB-like nuclease domain; Region: ParBc; pfam02195
511145001828	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
511145001829	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
511145001830	Active Sites [active]
511145001831	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
511145001832	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
511145001833	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145001834	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145001835	disulfide isomerase/thiol-disulfide oxidase; Provisional; Region: dsbG; PRK11657
511145001836	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
511145001837	dimerization domain [polypeptide binding]; other site
511145001838	dimer interface [polypeptide binding]; other site
511145001839	catalytic residues [active]
511145001840	alkyl hydroperoxide reductase subunit C; Provisional; Region: PRK10382
511145001841	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
511145001842	dimer interface [polypeptide binding]; other site
511145001843	decamer (pentamer of dimers) interface [polypeptide binding]; other site
511145001844	catalytic triad [active]
511145001845	peroxidatic and resolving cysteines [active]
511145001846	alkyl hydroperoxide reductase subunit F; Provisional; Region: PRK15317
511145001847	Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) family, N-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which in turn catalyzes the reduction...; Region: AhpF_NTD_N; cd02974
511145001848	catalytic residue [active]
511145001849	TRX-GRX-like family, Alkyl hydroperoxide reductase F subunit (AhpF) N-terminal domain (NTD) subfamily, C-terminal TRX-fold subdomain; AhpF is a homodimeric flavoenzyme which catalyzes the NADH-dependent reduction of the peroxiredoxin AhpC, which then...; Region: AhpF_NTD_C; cd03026
511145001850	catalytic residues [active]
511145001851	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145001852	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145001853	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145001854	Ligand Binding Site [chemical binding]; other site
511145001855	Glutathione-dependent formaldehyde dehydrogenase related proteins, child 1; Region: FDH_like_1; cd08283
511145001856	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145001857	NAD binding site [chemical binding]; other site
511145001858	catalytic Zn binding site [ion binding]; other site
511145001859	structural Zn binding site [ion binding]; other site
511145001860	nucleoside diphosphate kinase regulator; Provisional; Region: PRK05753
511145001861	Rnk N-terminus; Region: Rnk_N; pfam14760
511145001862	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
511145001863	Ribonuclease T2 (RNase T2) is a widespread family of secreted RNases found in every organism examined thus far.  This family includes RNase Rh, RNase MC1, RNase LE, and self-incompatibility RNases (S-RNases).  Plant T2 RNases are expressed during leaf...; Region: RNase_T2_prok; cd01062
511145001864	B1 nucleotide binding pocket [chemical binding]; other site
511145001865	B2 nucleotide binding pocket [chemical binding]; other site
511145001866	CAS motifs; other site
511145001867	active site
511145001868	anion transporter; Region: dass; TIGR00785
511145001869	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
511145001870	transmembrane helices; other site
511145001871	triphosphoribosyl-dephospho-CoA synthase; Provisional; Region: citG; PRK10096
511145001872	Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) [Coenzyme metabolism / Lipid metabolism]; Region: CitX; COG3697
511145001873	Citrate lyase, alpha subunit [Energy production and conversion]; Region: CitF; COG3051
511145001874	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
511145001875	Citrate lyase, gamma subunit [Energy production and conversion]; Region: CitD; COG3052
511145001876	Citrate lyase synthetase [Energy production and conversion]; Region: CitC; COG3053
511145001877	Citrate lyase ligase; Region: Citrate_lyase_ligase; cd02169
511145001878	putative active site [active]
511145001879	(T/H)XGH motif; other site
511145001880	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
511145001881	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
511145001882	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145001883	putative active site [active]
511145001884	heme pocket [chemical binding]; other site
511145001885	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
511145001886	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145001887	ATP binding site [chemical binding]; other site
511145001888	Mg2+ binding site [ion binding]; other site
511145001889	G-X-G motif; other site
511145001890	two-component response regulator DpiA; Provisional; Region: dpiA; PRK10046
511145001891	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145001892	active site
511145001893	phosphorylation site [posttranslational modification]
511145001894	intermolecular recognition site; other site
511145001895	dimerization interface [polypeptide binding]; other site
511145001896	Transcriptional regulator; Region: CitT; pfam12431
511145001897	C4-dicarboxylate transporter DcuC; Provisional; Region: dcuC; PRK10654
511145001898	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
511145001899	phospholipid:lipid A palmitoyltransferase; Provisional; Region: pagP; PRK11045
511145001900	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145001901	DNA-binding site [nucleotide binding]; DNA binding site
511145001902	RNA-binding motif; other site
511145001903	chromosome condensation membrane protein; Provisional; Region: PRK14196
511145001904	twin arginine translocase protein E; Validated; Region: tatE; PRK03625
511145001905	lipoyl synthase; Provisional; Region: PRK05481
511145001906	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145001907	FeS/SAM binding site; other site
511145001908	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11482
511145001909	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145001910	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145001911	dimerization interface [polypeptide binding]; other site
511145001912	lipoate-protein ligase B; Provisional; Region: PRK14342
511145001913	hypothetical protein; Provisional; Region: PRK04998
511145001914	D-alanyl-D-alanine carboxypeptidase fraction A; Provisional; Region: PRK10793
511145001915	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
511145001916	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
511145001917	rare lipoprotein A; Provisional; Region: PRK10672
511145001918	Rare lipoprotein A (RlpA)-like double-psi beta-barrel; Region: DPBB_1; pfam03330
511145001919	Sporulation related domain; Region: SPOR; pfam05036
511145001920	cell wall shape-determining protein; Provisional; Region: PRK10794
511145001921	penicillin-binding protein 2; Provisional; Region: PRK10795
511145001922	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
511145001923	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
511145001924	rRNA large subunit m3Psi methyltransferase RlmH; Region: tRNA_RlmH_YbeA; TIGR00246
511145001925	ribosome-associated protein; Provisional; Region: PRK11538
511145001926	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
511145001927	catalytic core [active]
511145001928	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
511145001929	active site
511145001930	(T/H)XGH motif; other site
511145001931	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
511145001932	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; pfam06144
511145001933	Processivity clamp loader gamma complex DNA pol III C-term; Region: DNA_pol3_delt_C; pfam14840
511145001934	LPS-assembly lipoprotein RlpB; Provisional; Region: PRK10796
511145001935	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
511145001936	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
511145001937	active site
511145001938	HIGH motif; other site
511145001939	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
511145001940	KMSKS motif; other site
511145001941	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
511145001942	tRNA binding surface [nucleotide binding]; other site
511145001943	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
511145001944	hypothetical protein; Provisional; Region: PRK11032
511145001945	Sel1-like repeats; Region: SEL1; smart00671
511145001946	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
511145001947	Sel1-like repeats; Region: SEL1; smart00671
511145001948	Sel1-like repeats; Region: SEL1; smart00671
511145001949	Sel1-like repeats; Region: SEL1; smart00671
511145001950	Sel1-like repeats; Region: SEL1; smart00671
511145001951	Sel1-like repeats; Region: SEL1; smart00671
511145001952	Sel1-like repeats; Region: SEL1; smart00671
511145001953	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
511145001954	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
511145001955	HSP70 interaction site [polypeptide binding]; other site
511145001956	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
511145001957	Sel1-like repeats; Region: SEL1; smart00671
511145001958	Sel1-like repeats; Region: SEL1; smart00671
511145001959	Sel1-like repeats; Region: SEL1; smart00671
511145001960	Protein of unknown function (DUF1266); Region: DUF1266; pfam06889
511145001961	DnaJ domain; Region: DnaJ; pfam00226
511145001962	Molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: DnaK; COG0443
511145001963	Nucleotide-binding domain of Escherichia coli HscC and similar proteins; Region: HscC_like_NBD; cd10235
511145001964	nucleotide binding site [chemical binding]; other site
511145001965	putative NEF/HSP70 interaction site [polypeptide binding]; other site
511145001966	SBD interface [polypeptide binding]; other site
511145001967	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
511145001968	active site
511145001969	tetramer interface [polypeptide binding]; other site
511145001970	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
511145001971	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
511145001972	Walker A/P-loop; other site
511145001973	ATP binding site [chemical binding]; other site
511145001974	Q-loop/lid; other site
511145001975	ABC transporter signature motif; other site
511145001976	Walker B; other site
511145001977	D-loop; other site
511145001978	H-loop/switch region; other site
511145001979	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
511145001980	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145001981	dimer interface [polypeptide binding]; other site
511145001982	conserved gate region; other site
511145001983	putative PBP binding loops; other site
511145001984	ABC-ATPase subunit interface; other site
511145001985	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
511145001986	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145001987	dimer interface [polypeptide binding]; other site
511145001988	conserved gate region; other site
511145001989	putative PBP binding loops; other site
511145001990	ABC-ATPase subunit interface; other site
511145001991	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
511145001992	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145001993	substrate binding pocket [chemical binding]; other site
511145001994	membrane-bound complex binding site; other site
511145001995	hinge residues; other site
511145001996	Transposase domain (DUF772); Region: DUF772; pfam05598
511145001997	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145001998	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145001999	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145002000	apolipoprotein N-acyltransferase; Reviewed; Region: lnt; PRK00302
511145002001	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
511145002002	putative active site [active]
511145002003	catalytic triad [active]
511145002004	putative dimer interface [polypeptide binding]; other site
511145002005	magnesium/cobalt efflux protein CorC; Provisional; Region: PRK15094
511145002006	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
511145002007	Transporter associated domain; Region: CorC_HlyC; smart01091
511145002008	metal-binding heat shock protein; Provisional; Region: PRK00016
511145002009	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
511145002010	PhoH-like protein; Region: PhoH; pfam02562
511145002011	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14325
511145002012	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
511145002013	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145002014	FeS/SAM binding site; other site
511145002015	TRAM domain; Region: TRAM; pfam01938
511145002016	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed; Region: ubiF; PRK08020
511145002017	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
511145002018	asparagine synthetase B; Provisional; Region: asnB; PRK09431
511145002019	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
511145002020	active site
511145002021	dimer interface [polypeptide binding]; other site
511145002022	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
511145002023	Ligand Binding Site [chemical binding]; other site
511145002024	Molecular Tunnel; other site
511145002025	UMP phosphatase; Provisional; Region: PRK10444
511145002026	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145002027	active site
511145002028	motif I; other site
511145002029	motif II; other site
511145002030	MarR family; Region: MarR_2; cl17246
511145002031	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145002032	ROK family; Region: ROK; pfam00480
511145002033	N-acetylglucosamine-6-phosphate deacetylase; Region: nagA; TIGR00221
511145002034	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
511145002035	active site
511145002036	dimer interface [polypeptide binding]; other site
511145002037	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
511145002038	active site
511145002039	trimer interface [polypeptide binding]; other site
511145002040	allosteric site; other site
511145002041	active site lid [active]
511145002042	hexamer (dimer of trimers) interface [polypeptide binding]; other site
511145002043	PTS system N-acetyl glucosamine specific transporter subunits IIABC; Provisional; Region: PRK10255
511145002044	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
511145002045	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145002046	active site turn [active]
511145002047	phosphorylation site [posttranslational modification]
511145002048	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
511145002049	HPr interaction site; other site
511145002050	glycerol kinase (GK) interaction site [polypeptide binding]; other site
511145002051	active site
511145002052	phosphorylation site [posttranslational modification]
511145002053	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
511145002054	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
511145002055	active site
511145002056	HIGH motif; other site
511145002057	KMSKS motif; other site
511145002058	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
511145002059	outer membrane porin, OprD family; Region: OprD; pfam03573
511145002060	YbfN-like lipoprotein; Region: YbfN; pfam13982
511145002061	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
511145002062	metal binding site 2 [ion binding]; metal-binding site
511145002063	putative DNA binding helix; other site
511145002064	metal binding site 1 [ion binding]; metal-binding site
511145002065	dimer interface [polypeptide binding]; other site
511145002066	structural Zn2+ binding site [ion binding]; other site
511145002067	ryhB-regulated fur leader peptide; Provisional; Region: PRK14761
511145002068	flavodoxin FldA; Validated; Region: PRK09267
511145002069	LexA regulated protein; Provisional; Region: PRK11675
511145002070	acyl-CoA esterase; Provisional; Region: PRK10673
511145002071	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
511145002072	replication initiation regulator SeqA; Provisional; Region: PRK11187
511145002073	phosphoglucomutase, alpha-D-glucose phosphate-specific; Region: pgm; TIGR01132
511145002074	This bacterial PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl...; Region: PGM_like3; cd05801
511145002075	active site
511145002076	substrate binding site [chemical binding]; other site
511145002077	metal binding site [ion binding]; metal-binding site
511145002078	putrescine transporter; Provisional; Region: potE; PRK10655
511145002079	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
511145002080	ornithine decarboxylase; Provisional; Region: PRK13578
511145002081	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
511145002082	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
511145002083	homodimer interface [polypeptide binding]; other site
511145002084	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002085	catalytic residue [active]
511145002086	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
511145002087	DNA-binding transcriptional activator KdpE; Provisional; Region: PRK10529
511145002088	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145002089	active site
511145002090	phosphorylation site [posttranslational modification]
511145002091	intermolecular recognition site; other site
511145002092	dimerization interface [polypeptide binding]; other site
511145002093	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145002094	DNA binding site [nucleotide binding]
511145002095	sensor protein KdpD; Provisional; Region: PRK10490
511145002096	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
511145002097	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
511145002098	Ligand Binding Site [chemical binding]; other site
511145002099	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
511145002100	GAF domain; Region: GAF_3; pfam13492
511145002101	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145002102	dimer interface [polypeptide binding]; other site
511145002103	phosphorylation site [posttranslational modification]
511145002104	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145002105	ATP binding site [chemical binding]; other site
511145002106	Mg2+ binding site [ion binding]; other site
511145002107	G-X-G motif; other site
511145002108	K+-transporting ATPase, c chain; Region: KdpC; pfam02669
511145002109	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
511145002110	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
511145002111	Soluble P-type ATPase [General function prediction only]; Region: COG4087
511145002112	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
511145002113	potassium-transporting ATPase subunit F; Provisional; Region: kdpF; PRK14748
511145002114	Protein of unknown function (DUF2517); Region: DUF2517; pfam10725
511145002115	PAAR motif; Region: PAAR_motif; cl15808
511145002116	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145002117	RHS Repeat; Region: RHS_repeat; pfam05593
511145002118	RHS Repeat; Region: RHS_repeat; pfam05593
511145002119	RHS Repeat; Region: RHS_repeat; pfam05593
511145002120	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145002121	RHS Repeat; Region: RHS_repeat; pfam05593
511145002122	RHS Repeat; Region: RHS_repeat; pfam05593
511145002123	RHS protein; Region: RHS; pfam03527
511145002124	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
511145002125	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
511145002126	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145002127	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145002128	hypothetical protein; Provisional; Region: PRK10167
511145002129	deoxyribodipyrimidine photolyase; Provisional; Region: PRK10674
511145002130	DNA photolyase; Region: DNA_photolyase; pfam00875
511145002131	FAD binding domain of DNA photolyase; Region: FAD_binding_7; pfam03441
511145002132	dipeptide/tripeptide permease D; Provisional; Region: PRK15462
511145002133	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
511145002134	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145002135	putative substrate translocation pore; other site
511145002136	metal-binding protein; Provisional; Region: PRK10799
511145002137	sensor histidine kinase inhibitor, KipI family; Region: TIGR00370
511145002138	biotin-dependent carboxylase uncharacterized domain; Region: urea_amlyse_rel; TIGR00724
511145002139	Escherichia coli putative lactam utilization protein YbgL and similar proteins; Region: LamB_YcsF_YbgL_like; cd10800
511145002140	putative active site [active]
511145002141	endonuclease VIII; Provisional; Region: PRK10445
511145002142	N-terminal domain of Escherichia coli Nei/endonuclease VIII and related DNA glycosylases; Region: EcNei-like_N; cd08965
511145002143	DNA binding site [nucleotide binding]
511145002144	catalytic residue [active]
511145002145	putative catalytic residues [active]
511145002146	H2TH interface [polypeptide binding]; other site
511145002147	intercalation triad [nucleotide binding]; other site
511145002148	substrate specificity determining residue; other site
511145002149	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
511145002150	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
511145002151	Putative ammonia monooxygenase [General function prediction only]; Region: AbrB; COG3180
511145002152	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
511145002153	membrane protein AbrB duplication; Region: Gneg_AbrB_dup; TIGR03082
511145002154	Fimbrial protein; Region: Fimbrial; pfam00419
511145002155	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
511145002156	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145002157	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145002158	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
511145002159	PapC N-terminal domain; Region: PapC_N; pfam13954
511145002160	Outer membrane usher protein; Region: Usher; pfam00577
511145002161	PapC C-terminal domain; Region: PapC_C; pfam13953
511145002162	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145002163	Escherichia coli (Ec) citrate synthase (CS) GltA_like. CS catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the citric acid cycle (TCA or Krebs cycle). The overall CS...; Region: EcCS_like; cd06114
511145002164	Citrate synthase [Energy production and conversion]; Region: GltA; COG0372
511145002165	dimer interface [polypeptide binding]; other site
511145002166	active site
511145002167	citrylCoA binding site [chemical binding]; other site
511145002168	NADH binding [chemical binding]; other site
511145002169	cationic pore residues; other site
511145002170	oxalacetate/citrate binding site [chemical binding]; other site
511145002171	coenzyme A binding site [chemical binding]; other site
511145002172	catalytic triad [active]
511145002173	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase C (SdhC) subunit; composed of bacterial SdhC and eukaryotic large cytochrome b binding (CybL) proteins. SQR catalyzes the oxidation of succinate to fumarate coupled to the...; Region: SQR_TypeC_SdhC; cd03499
511145002174	Iron-sulfur protein interface; other site
511145002175	proximal quinone binding site [chemical binding]; other site
511145002176	SdhD (CybS) interface [polypeptide binding]; other site
511145002177	proximal heme binding site [chemical binding]; other site
511145002178	Succinate:quinone oxidoreductase (SQR) Type C subfamily, Succinate dehydrogenase D (SdhD) subunit; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol. E. coli SQR, a member of this subfamily, reduces the...; Region: SQR_TypeC_SdhD; cd03494
511145002179	SdhC subunit interface [polypeptide binding]; other site
511145002180	proximal heme binding site [chemical binding]; other site
511145002181	cardiolipin binding site; other site
511145002182	Iron-sulfur protein interface; other site
511145002183	proximal quinone binding site [chemical binding]; other site
511145002184	succinate dehydrogenase flavoprotein subunit; Reviewed; Region: sdhA; PRK08958
511145002185	L-aspartate oxidase; Provisional; Region: PRK06175
511145002186	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
511145002187	succinate dehydrogenase iron-sulfur subunit; Reviewed; Region: sdhB; PRK05950
511145002188	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
511145002189	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
511145002190	2-oxoglutarate dehydrogenase E1 component; Reviewed; Region: sucA; PRK09404
511145002191	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
511145002192	TPP-binding site [chemical binding]; other site
511145002193	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
511145002194	dimer interface [polypeptide binding]; other site
511145002195	PYR/PP interface [polypeptide binding]; other site
511145002196	TPP binding site [chemical binding]; other site
511145002197	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
511145002198	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
511145002199	E3 interaction surface; other site
511145002200	lipoyl attachment site [posttranslational modification]; other site
511145002201	e3 binding domain; Region: E3_binding; pfam02817
511145002202	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
511145002203	succinyl-CoA synthetase subunit beta; Provisional; Region: sucC; PRK00696
511145002204	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
511145002205	CoA-ligase; Region: Ligase_CoA; pfam00549
511145002206	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
511145002207	CoA binding domain; Region: CoA_binding; pfam02629
511145002208	CoA-ligase; Region: Ligase_CoA; pfam00549
511145002209	DNA-binding transcriptional repressor MngR; Provisional; Region: PRK09764
511145002210	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145002211	DNA-binding site [nucleotide binding]; DNA binding site
511145002212	UTRA domain; Region: UTRA; pfam07702
511145002213	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
511145002214	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145002215	active site
511145002216	phosphorylation site [posttranslational modification]
511145002217	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145002218	active site
511145002219	P-loop; other site
511145002220	phosphorylation site [posttranslational modification]
511145002221	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
511145002222	alpha-mannosidase; Provisional; Region: PRK09819
511145002223	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
511145002224	active site
511145002225	metal binding site [ion binding]; metal-binding site
511145002226	catalytic site [active]
511145002227	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
511145002228	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
511145002229	cytochrome d terminal oxidase subunit 1; Provisional; Region: PRK15097
511145002230	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003
511145002231	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
511145002232	Membrane bound YbgT-like protein; Region: YbgT_YccB; cl02039
511145002233	hypothetical protein; Provisional; Region: PRK10588
511145002234	4-hydroxybenzoyl-CoA thioesterase (4HBT). Catalyzes the final step in the 4-chlorobenzoate degradation pathway in which 4-chlorobenzoate is converted to 4-hydroxybenzoate in certain soil-dwelling bacteria. 4HBT forms a homotetramer with four active sites; Region: 4HBT; cd00586
511145002235	active site
511145002236	colicin uptake protein TolQ; Provisional; Region: PRK10801
511145002237	colicin uptake protein TolR; Provisional; Region: PRK11024
511145002238	cell envelope integrity inner membrane protein TolA; Provisional; Region: tolA; PRK09510
511145002239	Double-stranded DNA-binding domain; Region: dsDNA_bind; cl00928
511145002240	TolA C-terminal; Region: TolA; pfam06519
511145002241	translocation protein TolB; Provisional; Region: tolB; PRK03629
511145002242	TolB amino-terminal domain; Region: TolB_N; pfam04052
511145002243	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
511145002244	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
511145002245	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
511145002246	peptidoglycan-associated outer membrane lipoprotein; Provisional; Region: PRK10802
511145002247	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
511145002248	ligand binding site [chemical binding]; other site
511145002249	tol-pal system protein YbgF; Provisional; Region: PRK10803
511145002250	Tetratricopeptide repeat; Region: TPR_6; pfam13174
511145002251	Tetratricopeptide repeat; Region: TPR_6; pfam13174
511145002252	quinolinate synthetase; Provisional; Region: PRK09375
511145002253	nicotinamide riboside transporter PnuC; Provisional; Region: PRK15397
511145002254	zinc transporter ZitB; Provisional; Region: PRK03557
511145002255	YbgS-like protein; Region: YbgS; pfam13985
511145002256	phospho-2-dehydro-3-deoxyheptonate aldolase; Validated; Region: PRK09261
511145002257	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
511145002258	catalytic core [active]
511145002259	galactose mutarotase_like; Region: galactose_mutarotase_like; cd09019
511145002260	active site
511145002261	catalytic residues [active]
511145002262	galactokinase; Provisional; Region: PRK05101
511145002263	Galactokinase galactose-binding signature; Region: GalKase_gal_bdg; pfam10509
511145002264	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
511145002265	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
511145002266	galactose-1-phosphate uridylyltransferase; Provisional; Region: PRK11720
511145002267	Galactose-1-phosphate uridyl transferase (GalT): This enzyme plays a key role in galactose metabolism by catalysing the transfer of a uridine 5'-phosphoryl group from UDP-galactose 1-phosphate. The structure of E.coli GalT reveals that the enzyme...; Region: GalT; cd00608
511145002268	dimer interface [polypeptide binding]; other site
511145002269	active site
511145002270	UDP-galactose-4-epimerase; Provisional; Region: PRK10675
511145002271	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
511145002272	NAD binding site [chemical binding]; other site
511145002273	homodimer interface [polypeptide binding]; other site
511145002274	active site
511145002275	substrate binding site [chemical binding]; other site
511145002276	putative molybdenum transport ATP-binding protein ModF; Provisional; Region: PRK10938
511145002277	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cd00267
511145002278	Walker A/P-loop; other site
511145002279	ATP binding site [chemical binding]; other site
511145002280	Q-loop/lid; other site
511145002281	ABC transporter signature motif; other site
511145002282	Walker B; other site
511145002283	D-loop; other site
511145002284	H-loop/switch region; other site
511145002285	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002286	Walker A/P-loop; other site
511145002287	ATP binding site [chemical binding]; other site
511145002288	Q-loop/lid; other site
511145002289	ABC transporter signature motif; other site
511145002290	Walker B; other site
511145002291	D-loop; other site
511145002292	H-loop/switch region; other site
511145002293	DNA-binding transcriptional regulator ModE; Provisional; Region: PRK10676
511145002294	N-terminal domain of molybdenum-binding protein [General function prediction only]; Region: ModE; COG2005
511145002295	molybdenum-pterin binding domain; Region: Mop; TIGR00638
511145002296	TOBE domain; Region: TOBE; pfam03459
511145002297	Protein of unknown function (DUF2592); Region: DUF2592; pfam10766
511145002298	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145002299	substrate binding pocket [chemical binding]; other site
511145002300	membrane-bound complex binding site; other site
511145002301	hinge residues; other site
511145002302	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
511145002303	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002304	dimer interface [polypeptide binding]; other site
511145002305	conserved gate region; other site
511145002306	putative PBP binding loops; other site
511145002307	ABC-ATPase subunit interface; other site
511145002308	molybdate transporter ATP-binding protein; Provisional; Region: modC; PRK11144
511145002309	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002310	Walker A/P-loop; other site
511145002311	ATP binding site [chemical binding]; other site
511145002312	Q-loop/lid; other site
511145002313	ABC transporter signature motif; other site
511145002314	Walker B; other site
511145002315	D-loop; other site
511145002316	H-loop/switch region; other site
511145002317	molybdenum-pterin binding domain; Region: Mop; TIGR00638
511145002318	pyridoxal phosphate (PLP) phosphatase; Provisional; Region: PRK10530
511145002319	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145002320	active site
511145002321	motif I; other site
511145002322	motif II; other site
511145002323	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145002324	6-phosphogluconolactonase; Provisional; Region: PRK11028
511145002325	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145002326	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145002327	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
511145002328	putative dimerization interface [polypeptide binding]; other site
511145002329	PrpF protein; Region: PrpF; pfam04303
511145002330	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
511145002331	anion transporter; Region: dass; TIGR00785
511145002332	transmembrane helices; other site
511145002333	putative hydratase; Provisional; Region: PRK11413
511145002334	Aconitase catalytic domain; Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: Aconitase; cl00285
511145002335	substrate binding site [chemical binding]; other site
511145002336	ligand binding site [chemical binding]; other site
511145002337	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
511145002338	substrate binding site [chemical binding]; other site
511145002339	acyl-CoA thioesterase; Provisional; Region: PRK10531
511145002340	Pectinesterase; Region: Pectinesterase; cl01911
511145002341	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
511145002342	substrate binding site [chemical binding]; other site
511145002343	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145002344	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145002345	inhibitor-cofactor binding pocket; inhibition site
511145002346	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002347	catalytic residue [active]
511145002348	biotin synthase; Provisional; Region: PRK15108
511145002349	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145002350	FeS/SAM binding site; other site
511145002351	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
511145002352	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
511145002353	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
511145002354	substrate-cofactor binding pocket; other site
511145002355	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002356	catalytic residue [active]
511145002357	biotin biosynthesis protein BioC; Region: BioC; TIGR02072
511145002358	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145002359	S-adenosylmethionine binding site [chemical binding]; other site
511145002360	AAA domain; Region: AAA_26; pfam13500
511145002361	Dethiobiotin synthetase (DTBS) is the penultimate enzyme in the biotin biosynthesis pathway in Escherichia coli and other microorganisms. The enzyme catalyzes formation of the ureido ring of dethiobiotin from (7R,8S)-7,8-diaminononanoic acid (DAPA) and...; Region: DTBS; cd03109
511145002362	active site
511145002363	ADP binding site [chemical binding]; other site
511145002364	excinuclease ABC subunit B; Provisional; Region: PRK05298
511145002365	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145002366	ATP binding site [chemical binding]; other site
511145002367	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145002368	nucleotide binding region [chemical binding]; other site
511145002369	ATP-binding site [chemical binding]; other site
511145002370	Ultra-violet resistance protein B; Region: UvrB; pfam12344
511145002371	UvrB/uvrC motif; Region: UVR; pfam02151
511145002372	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
511145002373	phosphate binding site [ion binding]; other site
511145002374	putative substrate binding pocket [chemical binding]; other site
511145002375	dimer interface [polypeptide binding]; other site
511145002376	molybdenum cofactor biosynthesis protein A; Reviewed; Region: moaA; PRK00164
511145002377	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145002378	FeS/SAM binding site; other site
511145002379	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
511145002380	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
511145002381	MPT binding site; other site
511145002382	trimer interface [polypeptide binding]; other site
511145002383	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
511145002384	trimer interface [polypeptide binding]; other site
511145002385	dimer interface [polypeptide binding]; other site
511145002386	putative active site [active]
511145002387	Ubiquitin domain of MoaD-like proteins; Region: MoaD; cd00754
511145002388	MoaE interaction surface [polypeptide binding]; other site
511145002389	MoeB interaction surface [polypeptide binding]; other site
511145002390	thiocarboxylated glycine; other site
511145002391	MoaE family. Members of this family are involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor for a diverse group of redox enzymes. Moco biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoaE; cd00756
511145002392	MoaE homodimer interface [polypeptide binding]; other site
511145002393	MoaD interaction [polypeptide binding]; other site
511145002394	active site residues [active]
511145002395	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
511145002396	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
511145002397	Predicted integral membrane protein [Function unknown]; Region: COG0392
511145002398	cardiolipin synthase 2; Provisional; Region: PRK11263
511145002399	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
511145002400	putative active site [active]
511145002401	catalytic site [active]
511145002402	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase ybhO and similar proteins; Region: PLDc_ybhO_like_2; cd09159
511145002403	putative active site [active]
511145002404	catalytic site [active]
511145002405	Metal-dependent hydrolase [General function prediction only]; Region: ElsH; COG3568
511145002406	putative catalytic site [active]
511145002407	putative metal binding site [ion binding]; other site
511145002408	putative phosphate binding site [ion binding]; other site
511145002409	Putative inner membrane protein YbhQ; Region: YbhQ; pfam11076
511145002410	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
511145002411	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
511145002412	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
511145002413	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
511145002414	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
511145002415	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
511145002416	Walker A/P-loop; other site
511145002417	ATP binding site [chemical binding]; other site
511145002418	Q-loop/lid; other site
511145002419	ABC transporter signature motif; other site
511145002420	Walker B; other site
511145002421	D-loop; other site
511145002422	H-loop/switch region; other site
511145002423	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
511145002424	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
511145002425	Walker A/P-loop; other site
511145002426	ATP binding site [chemical binding]; other site
511145002427	Q-loop/lid; other site
511145002428	ABC transporter signature motif; other site
511145002429	Walker B; other site
511145002430	D-loop; other site
511145002431	H-loop/switch region; other site
511145002432	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
511145002433	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145002434	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145002435	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11552
511145002436	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145002437	Domain of unknown function (DUF1956); Region: DUF1956; pfam09209
511145002438	ATP-dependent RNA helicase RhlE; Provisional; Region: PRK10590
511145002439	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
511145002440	ATP binding site [chemical binding]; other site
511145002441	Mg++ binding site [ion binding]; other site
511145002442	motif III; other site
511145002443	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145002444	nucleotide binding region [chemical binding]; other site
511145002445	ATP-binding site [chemical binding]; other site
511145002446	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3236
511145002447	ATP-dependent DNA helicase DinG; Provisional; Region: dinG; PRK11747
511145002448	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
511145002449	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
511145002450	glycosyl transferase family protein; Provisional; Region: PRK08136
511145002451	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
511145002452	putative dehydrogenase; Provisional; Region: PRK10098
511145002453	hypothetical protein; Provisional; Region: PRK10259
511145002454	hypothetical protein; Provisional; Region: PRK11019
511145002455	Fe(II)-dependent oxygenase superfamily protein; Provisional; Region: PRK05467
511145002456	catecholate siderophore receptor Fiu; Provisional; Region: PRK09840
511145002457	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145002458	N-terminal plug; other site
511145002459	ligand-binding site [chemical binding]; other site
511145002460	Protein of unknown function (DUF1471); Region: DUF1471; cl11507
511145002461	23S rRNA mA1618 methyltransferase; Provisional; Region: PRK11727
511145002462	putative mechanosensitive channel protein; Provisional; Region: PRK11465
511145002463	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145002464	glutamine ABC transporter ATP-binding protein; Reviewed; Region: glnQ; PRK09493
511145002465	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
511145002466	Walker A/P-loop; other site
511145002467	ATP binding site [chemical binding]; other site
511145002468	Q-loop/lid; other site
511145002469	ABC transporter signature motif; other site
511145002470	Walker B; other site
511145002471	D-loop; other site
511145002472	H-loop/switch region; other site
511145002473	glutamine ABC transporter permease protein; Reviewed; Region: glnP; PRK09494
511145002474	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002475	dimer interface [polypeptide binding]; other site
511145002476	conserved gate region; other site
511145002477	putative PBP binding loops; other site
511145002478	ABC-ATPase subunit interface; other site
511145002479	glutamine ABC transporter periplasmic protein; Reviewed; Region: glnH; PRK09495
511145002480	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145002481	substrate binding pocket [chemical binding]; other site
511145002482	membrane-bound complex binding site; other site
511145002483	hinge residues; other site
511145002484	Ferritin-like domain; Region: Ferritin; pfam00210
511145002485	DPS protein, ferritin-like diiron-binding domain; Region: DPS; cd01043
511145002486	dimerization interface [polypeptide binding]; other site
511145002487	DPS ferroxidase diiron center [ion binding]; other site
511145002488	ion pore; other site
511145002489	threonine and homoserine efflux system; Provisional; Region: PRK10532
511145002490	EamA-like transporter family; Region: EamA; pfam00892
511145002491	outer membrane protein X; Provisional; Region: ompX; PRK09408
511145002492	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
511145002493	Sulfatase; Region: Sulfatase; pfam00884
511145002494	manganese transport regulator MntR; Provisional; Region: PRK11050
511145002495	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
511145002496	Iron dependent repressor, metal binding and dimerization domain; Region: Fe_dep_repr_C; pfam02742
511145002497	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
511145002498	Putative anion permease YbiR.  Based on sequence similarity, YbiR proteins are predicted to function as anion translocating permeases in eubacteria, archaea and plants. They belong to ArsB/NhaD superfamily of permeases that have been shown to translocate...; Region: YbiR_permease; cd01117
511145002499	transmembrane helices; other site
511145002500	L,D-transpeptidase; Provisional; Region: PRK10260
511145002501	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145002502	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
511145002503	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145002504	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002505	Walker A/P-loop; other site
511145002506	ATP binding site [chemical binding]; other site
511145002507	ABC transporter signature motif; other site
511145002508	Walker B; other site
511145002509	ABC transporter; Region: ABC_tran_2; pfam12848
511145002510	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145002511	Protein of unknown function (DUF1479); Region: DUF1479; pfam07350
511145002512	Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; Region: Cof-subfamily; TIGR00099
511145002513	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145002514	active site
511145002515	motif I; other site
511145002516	motif II; other site
511145002517	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145002518	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
511145002519	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
511145002520	dimer interface [polypeptide binding]; other site
511145002521	active site
511145002522	glycine loop; other site
511145002523	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
511145002524	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
511145002525	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
511145002526	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
511145002527	active site
511145002528	intersubunit interactions; other site
511145002529	catalytic residue [active]
511145002530	molybdopterin biosynthesis protein MoeB; Provisional; Region: PRK05690
511145002531	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
511145002532	ATP binding site [chemical binding]; other site
511145002533	substrate interface [chemical binding]; other site
511145002534	molybdopterin biosynthesis protein MoeA; Provisional; Region: PRK10680
511145002535	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
511145002536	dimer interface [polypeptide binding]; other site
511145002537	putative functional site; other site
511145002538	putative MPT binding site; other site
511145002539	L-Asparaginase type 2. L-Asparaginase hydrolyzes L-asparagine to L-aspartate and ammonia. The proenzyme undergoes an autoproteolytic cleavage into alpha and beta subunits to expose a threonine residue which becomes the N-terminal residue of the beta...; Region: Asparaginase_2; cd04701
511145002540	catalytic nucleophile [active]
511145002541	glutathione transporter ATP-binding protein; Provisional; Region: PRK10261
511145002542	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145002543	Walker A/P-loop; other site
511145002544	ATP binding site [chemical binding]; other site
511145002545	Q-loop/lid; other site
511145002546	ABC transporter signature motif; other site
511145002547	Walker B; other site
511145002548	D-loop; other site
511145002549	H-loop/switch region; other site
511145002550	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145002551	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145002552	Walker A/P-loop; other site
511145002553	ATP binding site [chemical binding]; other site
511145002554	Q-loop/lid; other site
511145002555	ABC transporter signature motif; other site
511145002556	Walker B; other site
511145002557	D-loop; other site
511145002558	H-loop/switch region; other site
511145002559	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
511145002560	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
511145002561	The substrate-binding component of an uncharacterized ABC-type peptide import system Ylib contains the type 2 periplasmic binding fold; Region: PBP2_Ylib_like; cd08499
511145002562	glutathione ABC transporter permease GsiC; Provisional; Region: PRK15081
511145002563	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002564	dimer interface [polypeptide binding]; other site
511145002565	conserved gate region; other site
511145002566	putative PBP binding loops; other site
511145002567	ABC-ATPase subunit interface; other site
511145002568	glutathione ABC transporter permease GsiD; Provisional; Region: PRK15082
511145002569	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
511145002570	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002571	dimer interface [polypeptide binding]; other site
511145002572	conserved gate region; other site
511145002573	putative PBP binding loops; other site
511145002574	ABC-ATPase subunit interface; other site
511145002575	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145002576	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145002577	metal binding site [ion binding]; metal-binding site
511145002578	active site
511145002579	I-site; other site
511145002580	ribosomal protein S12 methylthiotransferase; Provisional; Region: rimO; PRK14862
511145002581	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
511145002582	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145002583	FeS/SAM binding site; other site
511145002584	biofilm formation regulatory protein BssR; Reviewed; Region: bssR; PRK12302
511145002585	dehydrogenase, PQQ-dependent, s-GDH family; Region: non_repeat_PQQ; cl19645
511145002586	Glucose / Sorbosone dehydrogenase; Region: GSDH; pfam07995
511145002587	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
511145002588	GST_N family, unknown subfamily 2; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_2; cd03047
511145002589	putative C-terminal domain interface [polypeptide binding]; other site
511145002590	putative GSH binding site (G-site) [chemical binding]; other site
511145002591	putative dimer interface [polypeptide binding]; other site
511145002592	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
511145002593	N-terminal domain interface [polypeptide binding]; other site
511145002594	dimer interface [polypeptide binding]; other site
511145002595	substrate binding pocket (H-site) [chemical binding]; other site
511145002596	D-alanyl-D-alanine carboxypeptidase fraction C; Provisional; Region: PRK10001
511145002597	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
511145002598	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
511145002599	DNA-binding transcriptional repressor DeoR; Provisional; Region: PRK10681
511145002600	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145002601	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145002602	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
511145002603	PAP2_like proteins, BcrC_like subfamily. Several members of this family have been annotated as bacitracin transport permeases, as it was suspected that they form the permease component of an ABC transporter system. It was shown, however, that BcrC from...; Region: PAP2_BcrC_like; cd03385
511145002604	active site
511145002605	multidrug efflux system translocase MdfA; Provisional; Region: PRK15402
511145002606	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145002607	putative substrate translocation pore; other site
511145002608	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
511145002609	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145002610	active site
511145002611	motif I; other site
511145002612	motif II; other site
511145002613	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145002614	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145002615	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
511145002616	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145002617	putative substrate translocation pore; other site
511145002618	transcriptional repressor BetI; Region: betaine_BetI; TIGR03384
511145002619	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145002620	Bacterial transcriptional repressor; Region: TetR_C_6; pfam13977
511145002621	putative transporter; Provisional; Region: PRK04972
511145002622	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
511145002623	TrkA-C domain; Region: TrkA_C; pfam02080
511145002624	TrkA-C domain; Region: TrkA_C; pfam02080
511145002625	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
511145002626	Putative inner membrane protein of Enterobacteriaceae; Region: YbjM; pfam11045
511145002627	Glutaredoxin (GRX) family; composed of GRX, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide...; Region: GRX_family; cd02066
511145002628	GSH binding site [chemical binding]; other site
511145002629	catalytic residues [active]
511145002630	Protein of unknown function (DUF1418); Region: DUF1418; pfam07214
511145002631	This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as...; Region: NfsA_FRP; cd02146
511145002632	dimer interface [polypeptide binding]; other site
511145002633	FMN binding site [chemical binding]; other site
511145002634	NADPH bind site [chemical binding]; other site
511145002635	ribosomal protein S6 modification protein; Provisional; Region: PRK10446
511145002636	RimK-like ATP-grasp domain; Region: RimK; pfam08443
511145002637	Putative bacterial sensory transduction regulator; Region: YbjN; pfam10722
511145002638	putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Provisional; Region: PRK10682
511145002639	putrescine transporter ATP-binding subunit; Provisional; Region: potG; PRK11607
511145002640	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002641	Walker A/P-loop; other site
511145002642	ATP binding site [chemical binding]; other site
511145002643	Q-loop/lid; other site
511145002644	ABC transporter signature motif; other site
511145002645	Walker B; other site
511145002646	D-loop; other site
511145002647	H-loop/switch region; other site
511145002648	TOBE domain; Region: TOBE_2; pfam08402
511145002649	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002650	dimer interface [polypeptide binding]; other site
511145002651	conserved gate region; other site
511145002652	putative PBP binding loops; other site
511145002653	ABC-ATPase subunit interface; other site
511145002654	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
511145002655	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002656	dimer interface [polypeptide binding]; other site
511145002657	conserved gate region; other site
511145002658	putative PBP binding loops; other site
511145002659	ABC-ATPase subunit interface; other site
511145002660	Protein of unknown function (DUF2593); Region: DUF2593; pfam10767
511145002661	23S rRNA (uracil-5-)-methyltransferase RumB; Region: meth_trns_rumB; TIGR02085
511145002662	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145002663	S-adenosylmethionine binding site [chemical binding]; other site
511145002664	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
511145002665	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145002666	substrate binding pocket [chemical binding]; other site
511145002667	membrane-bound complex binding site; other site
511145002668	hinge residues; other site
511145002669	arginine transporter permease subunit ArtM; Provisional; Region: artM; PRK11122
511145002670	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002671	dimer interface [polypeptide binding]; other site
511145002672	conserved gate region; other site
511145002673	putative PBP binding loops; other site
511145002674	ABC-ATPase subunit interface; other site
511145002675	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
511145002676	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002677	dimer interface [polypeptide binding]; other site
511145002678	conserved gate region; other site
511145002679	putative PBP binding loops; other site
511145002680	ABC-ATPase subunit interface; other site
511145002681	putative ABC transporter arginine-biding protein; Provisional; Region: PRK15007
511145002682	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145002683	substrate binding pocket [chemical binding]; other site
511145002684	membrane-bound complex binding site; other site
511145002685	hinge residues; other site
511145002686	arginine transporter ATP-binding subunit; Provisional; Region: artP; PRK11124
511145002687	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002688	Walker A/P-loop; other site
511145002689	ATP binding site [chemical binding]; other site
511145002690	Q-loop/lid; other site
511145002691	ABC transporter signature motif; other site
511145002692	Walker B; other site
511145002693	D-loop; other site
511145002694	H-loop/switch region; other site
511145002695	putative lipoprotein; Provisional; Region: PRK10533
511145002696	hypothetical protein; Provisional; Region: PRK02877
511145002697	N-acetyl-anhydromuramyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: ampD; COG3023
511145002698	Peptidoglycan recognition proteins (PGRPs) are pattern recognition receptors that bind, and in certain cases, hydrolyze peptidoglycans (PGNs) of bacterial cell walls. PGRPs have been divided into three classes: short PGRPs (PGRP-S), that are small (20...; Region: PGRP; cd06583
511145002699	amidase catalytic site [active]
511145002700	Zn binding residues [ion binding]; other site
511145002701	substrate binding site [chemical binding]; other site
511145002702	The URO-D_CIMS_like protein superfamily includes bacterial and eukaryotic uroporphyrinogen decarboxylases (URO-D), coenzyme M methyltransferases and other putative bacterial methyltransferases, as well as cobalamine (B12) independent methionine synthases; Region: URO-D_CIMS_like; cl00464
511145002703	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
511145002704	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
511145002705	NAD(P) binding site [chemical binding]; other site
511145002706	active site
511145002707	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
511145002708	atypical (a) SDRs, subgroup 2; Region: SDR_a2; cd05245
511145002709	putative NAD(P) binding site [chemical binding]; other site
511145002710	putative active site [active]
511145002711	Protein of unknown function (DUF2867); Region: DUF2867; pfam11066
511145002712	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
511145002713	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
511145002714	tetramer interface [polypeptide binding]; other site
511145002715	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002716	catalytic residue [active]
511145002717	pyruvate dehydrogenase; Provisional; Region: PRK09124
511145002718	Pyrimidine (PYR) binding domain of POX; Region: TPP_PYR_POX; cd07039
511145002719	PYR/PP interface [polypeptide binding]; other site
511145002720	dimer interface [polypeptide binding]; other site
511145002721	tetramer interface [polypeptide binding]; other site
511145002722	TPP binding site [chemical binding]; other site
511145002723	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
511145002724	Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates...; Region: TPP_POX; cd02014
511145002725	TPP-binding site [chemical binding]; other site
511145002726	HCP oxidoreductase, NADH-dependent; Provisional; Region: PRK10684
511145002727	Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron...; Region: FNR_iron_sulfur_binding_1; cd06215
511145002728	FAD binding pocket [chemical binding]; other site
511145002729	FAD binding motif [chemical binding]; other site
511145002730	phosphate binding motif [ion binding]; other site
511145002731	beta-alpha-beta structure motif; other site
511145002732	NAD binding pocket [chemical binding]; other site
511145002733	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145002734	catalytic loop [active]
511145002735	iron binding site [ion binding]; other site
511145002736	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
511145002737	cubane metal cluster [ion binding]; other site
511145002738	hybrid metal cluster; other site
511145002739	Predicted membrane protein [Function unknown]; Region: COG2431
511145002740	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
511145002741	amphipathic channel; other site
511145002742	Asn-Pro-Ala signature motifs; other site
511145002743	Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair]; Region: COG3593
511145002744	AAA domain; Region: AAA_21; pfam13304
511145002745	TOPRIM_OLD: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in bacterial and archaeal nucleases of the OLD (overcome lysogenization defect) family.  The bacteriophage P2 OLD protein, which has DNase as well as...; Region: TOPRIM_OLD; cd01026
511145002746	putative active site [active]
511145002747	putative metal-binding site [ion binding]; other site
511145002748	Protein of unknown function (DUF535); Region: DUF535; pfam04393
511145002749	macrolide transporter subunit MacA; Provisional; Region: PRK11578
511145002750	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145002751	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145002752	macrolide transporter ATP-binding /permease protein; Provisional; Region: PRK10535
511145002753	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
511145002754	Walker A/P-loop; other site
511145002755	ATP binding site [chemical binding]; other site
511145002756	Q-loop/lid; other site
511145002757	ABC transporter signature motif; other site
511145002758	Walker B; other site
511145002759	D-loop; other site
511145002760	H-loop/switch region; other site
511145002761	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
511145002762	FtsX-like permease family; Region: FtsX; pfam02687
511145002763	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145002764	DNA-binding site [nucleotide binding]; DNA binding site
511145002765	RNA-binding motif; other site
511145002766	ATP-dependent Clp protease adaptor protein ClpS; Reviewed; Region: clpS; PRK00033
511145002767	ATP-dependent Clp protease ATP-binding subunit; Provisional; Region: clpA; PRK11034
511145002768	Clp amino terminal domain; Region: Clp_N; pfam02861
511145002769	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145002770	Walker A motif; other site
511145002771	ATP binding site [chemical binding]; other site
511145002772	Walker B motif; other site
511145002773	arginine finger; other site
511145002774	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145002775	Walker A motif; other site
511145002776	ATP binding site [chemical binding]; other site
511145002777	Walker B motif; other site
511145002778	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
511145002779	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
511145002780	rRNA binding site [nucleotide binding]; other site
511145002781	predicted 30S ribosome binding site; other site
511145002782	leucyl/phenylalanyl-tRNA--protein transferase; Reviewed; Region: aat; PRK00301
511145002783	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11160
511145002784	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145002785	ATP-binding cassette domain of CydCD, subfamily C; Region: ABCC_cytochrome_bd; cd03247
511145002786	Walker A/P-loop; other site
511145002787	ATP binding site [chemical binding]; other site
511145002788	Q-loop/lid; other site
511145002789	ABC transporter signature motif; other site
511145002790	Walker B; other site
511145002791	D-loop; other site
511145002792	H-loop/switch region; other site
511145002793	cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed; Region: PRK11174
511145002794	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145002795	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145002796	Walker A/P-loop; other site
511145002797	ATP binding site [chemical binding]; other site
511145002798	Q-loop/lid; other site
511145002799	ABC transporter signature motif; other site
511145002800	Walker B; other site
511145002801	D-loop; other site
511145002802	H-loop/switch region; other site
511145002803	thioredoxin reductase; Provisional; Region: PRK10262
511145002804	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145002805	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145002806	leucine-responsive transcriptional regulator; Provisional; Region: PRK11169
511145002807	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145002808	putative DNA binding site [nucleotide binding]; other site
511145002809	putative Zn2+ binding site [ion binding]; other site
511145002810	AsnC family; Region: AsnC_trans_reg; pfam01037
511145002811	DNA translocase FtsK; Provisional; Region: PRK10263
511145002812	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
511145002813	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
511145002814	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
511145002815	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
511145002816	periplasmic chaperone LolA; Region: lolA; TIGR00547
511145002817	recombination factor protein RarA; Reviewed; Region: PRK13342
511145002818	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145002819	Walker A motif; other site
511145002820	ATP binding site [chemical binding]; other site
511145002821	Walker B motif; other site
511145002822	arginine finger; other site
511145002823	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
511145002824	seryl-tRNA synthetase; Provisional; Region: PRK05431
511145002825	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
511145002826	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
511145002827	dimer interface [polypeptide binding]; other site
511145002828	active site
511145002829	motif 1; other site
511145002830	motif 2; other site
511145002831	motif 3; other site
511145002832	anaerobic dimethyl sulfoxide reductase subunit A; Provisional; Region: PRK14990
511145002833	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
511145002834	putative [Fe4-S4] binding site [ion binding]; other site
511145002835	putative molybdopterin cofactor binding site [chemical binding]; other site
511145002836	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
511145002837	putative molybdopterin cofactor binding site; other site
511145002838	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
511145002839	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145002840	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
511145002841	YcaC related amidohydrolases; E.coli YcaC is an homooctameric hydrolase with unknown specificity. Despite its weak sequence similarity, it is structurally related to other amidohydrolases and shares conserved active site residues with them; Region: YcaC_related; cd01012
511145002842	catalytic triad [active]
511145002843	dimer interface [polypeptide binding]; other site
511145002844	conserved cis-peptide bond; other site
511145002845	putative MFS family transporter protein; Provisional; Region: PRK03633
511145002846	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145002847	putative substrate translocation pore; other site
511145002848	Amino acid permease; Region: AA_permease_2; pfam13520
511145002849	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145002850	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145002851	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
511145002852	putative effector binding pocket; other site
511145002853	putative dimerization interface [polypeptide binding]; other site
511145002854	hypothetical protein; Provisional; Region: PRK09739
511145002855	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
511145002856	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145002857	FeS/SAM binding site; other site
511145002858	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
511145002859	Pyruvate formate lyase 1; Region: PFL1; cd01678
511145002860	coenzyme A binding site [chemical binding]; other site
511145002861	active site
511145002862	catalytic residues [active]
511145002863	glycine loop; other site
511145002864	formate transporter; Provisional; Region: PRK10805
511145002865	uncharacterized domain; Region: TIGR00702
511145002866	Predicted membrane protein [Function unknown]; Region: COG2323
511145002867	Phosphoserine aminotransferase (PSAT) family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major group in this CD corresponds to phosphoserine aminotransferase (PSAT).  PSAT is active as...; Region: PSAT_like; cd00611
511145002868	homodimer interface [polypeptide binding]; other site
511145002869	substrate-cofactor binding pocket; other site
511145002870	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002871	catalytic residue [active]
511145002872	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
511145002873	Enol pyruvate transferases family includes EPSP synthases and UDP-N-acetylglucosamine enolpyruvyl transferase. Both enzymes catalyze the reaction of enolpyruvyl transfer; Region: EPT-like; cd01554
511145002874	hinge; other site
511145002875	active site
511145002876	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
511145002877	cytidylate kinase; Provisional; Region: cmk; PRK00023
511145002878	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
511145002879	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
511145002880	active site
511145002881	CMP-binding site; other site
511145002882	The sites determining sugar specificity; other site
511145002883	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
511145002884	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
511145002885	RNA binding site [nucleotide binding]; other site
511145002886	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
511145002887	RNA binding site [nucleotide binding]; other site
511145002888	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
511145002889	RNA binding site [nucleotide binding]; other site
511145002890	S1_RPS1_repeat_ec4: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec4; cd05689
511145002891	RNA binding site [nucleotide binding]; other site
511145002892	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
511145002893	RNA binding site [nucleotide binding]; other site
511145002894	S1_RPS1_repeat_ec6: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec6; cd05691
511145002895	RNA binding site [nucleotide binding]; other site
511145002896	Beta subunit of integration host factor (IHFB); Region: IHF_B; cd13836
511145002897	dimer interface [polypeptide binding]; other site
511145002898	DNA binding site [nucleotide binding]
511145002899	ComEC family competence protein; Provisional; Region: PRK11539
511145002900	Domain of unknown function (DUF4131); Region: DUF4131; pfam13567
511145002901	ComEC/Rec2-related protein; Region: ComEC_N-term; TIGR00360
511145002902	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
511145002903	lipid transporter ATP-binding/permease protein; Provisional; Region: PRK11176
511145002904	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145002905	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
511145002906	Walker A/P-loop; other site
511145002907	ATP binding site [chemical binding]; other site
511145002908	Q-loop/lid; other site
511145002909	ABC transporter signature motif; other site
511145002910	Walker B; other site
511145002911	D-loop; other site
511145002912	H-loop/switch region; other site
511145002913	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
511145002914	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3214
511145002915	hypothetical protein; Provisional; Region: PRK11827
511145002916	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
511145002917	Ligand binding site; other site
511145002918	oligomer interface; other site
511145002919	hypothetical protein; Provisional; Region: PRK10593
511145002920	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
511145002921	putative active site [active]
511145002922	Methyltransferase domain; Region: Methyltransf_31; pfam13847
511145002923	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145002924	S-adenosylmethionine binding site [chemical binding]; other site
511145002925	condesin subunit F; Provisional; Region: PRK05260
511145002926	condesin subunit E; Provisional; Region: PRK05256
511145002927	Uncharacterized protein involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: MukB; COG3096
511145002928	MukB N-terminal; Region: MukB; pfam04310
511145002929	Putative exonuclease SbcCD, C subunit; Region: SbcCD_C; pfam13558
511145002930	murein L,D-transpeptidase; Provisional; Region: PRK10594
511145002931	K+ potassium transporter; Region: K_trans; cl15781
511145002932	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
511145002933	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145002934	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3108
511145002935	Peptidase M15; Region: Peptidase_M15_3; cl01194
511145002936	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
511145002937	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
511145002938	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145002939	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145002940	homodimer interface [polypeptide binding]; other site
511145002941	catalytic residue [active]
511145002942	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
511145002943	trimer interface [polypeptide binding]; other site
511145002944	eyelet of channel; other site
511145002945	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
511145002946	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
511145002947	putative dimer interface [polypeptide binding]; other site
511145002948	putative anticodon binding site; other site
511145002949	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
511145002950	homodimer interface [polypeptide binding]; other site
511145002951	motif 1; other site
511145002952	motif 2; other site
511145002953	active site
511145002954	motif 3; other site
511145002955	nicotinate phosphoribosyltransferase; Region: NAPRTase; TIGR01514
511145002956	Nicotinate phosphoribosyltransferase (NAPRTase), related to PncB. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting; Region: PncB_like; cd01401
511145002957	active site
511145002958	aminopeptidase N; Provisional; Region: pepN; PRK14015
511145002959	Peptidase M1 family containing Aminopeptidase N; Region: M1_APN_1; cd09600
511145002960	active site
511145002961	Zn binding site [ion binding]; other site
511145002962	aliphatic sulfonates transport ATP-binding subunit; Provisional; Region: ssuB; PRK11247
511145002963	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
511145002964	Walker A/P-loop; other site
511145002965	ATP binding site [chemical binding]; other site
511145002966	Q-loop/lid; other site
511145002967	ABC transporter signature motif; other site
511145002968	Walker B; other site
511145002969	D-loop; other site
511145002970	H-loop/switch region; other site
511145002971	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
511145002972	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145002973	dimer interface [polypeptide binding]; other site
511145002974	conserved gate region; other site
511145002975	putative PBP binding loops; other site
511145002976	ABC-ATPase subunit interface; other site
511145002977	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
511145002978	active site
511145002979	dimer interface [polypeptide binding]; other site
511145002980	non-prolyl cis peptide bond; other site
511145002981	insertion regions; other site
511145002982	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145002983	substrate binding pocket [chemical binding]; other site
511145002984	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
511145002985	membrane-bound complex binding site; other site
511145002986	hinge residues; other site
511145002987	NAD(P)H-dependent FMN reductase; Provisional; Region: PRK10569
511145002988	Fimbrial protein; Region: Fimbrial; cl01416
511145002989	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
511145002990	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145002991	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145002992	outer membrane usher protein; Provisional; Region: PRK15193
511145002993	PapC N-terminal domain; Region: PapC_N; pfam13954
511145002994	Outer membrane usher protein; Region: Usher; pfam00577
511145002995	PapC C-terminal domain; Region: PapC_C; pfam13953
511145002996	Fimbrial protein; Region: Fimbrial; cl01416
511145002997	Fimbrial protein; Region: Fimbrial; cl01416
511145002998	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145002999	putativi pili assembly chaperone; Provisional; Region: PRK11385
511145003000	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145003001	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145003002	dihydroorotate dehydrogenase 2; Reviewed; Region: PRK05286
511145003003	Dihydroorotate dehydrogenase (DHOD) class 2. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine nucleotides. DHOD requires...; Region: DHOD_2_like; cd04738
511145003004	quinone interaction residues [chemical binding]; other site
511145003005	active site
511145003006	catalytic residues [active]
511145003007	FMN binding site [chemical binding]; other site
511145003008	substrate binding site [chemical binding]; other site
511145003009	Protein of unknown function (DUF1379); Region: DUF1379; pfam07126
511145003010	Uncharacterized Fe-S protein [General function prediction only]; Region: COG3217
511145003011	MOSC N-terminal beta barrel domain; Region: MOSC_N; pfam03476
511145003012	MOSC domain; Region: MOSC; pfam03473
511145003013	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145003014	catalytic loop [active]
511145003015	iron binding site [ion binding]; other site
511145003016	23S rRNA m(2)G2445 methyltransferase; Provisional; Region: rlmL; PRK11783
511145003017	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
511145003018	Putative RNA methylase family UPF0020; Region: UPF0020; pfam01170
511145003019	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145003020	S-adenosylmethionine binding site [chemical binding]; other site
511145003021	ABC transporter ATPase component; Reviewed; Region: PRK11147
511145003022	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145003023	ABC transporter; Region: ABC_tran_2; pfam12848
511145003024	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145003025	paraquat-inducible membrane protein A; Provisional; Region: PRK15103
511145003026	Paraquat-inducible protein A; Region: PqiA; pfam04403
511145003027	Paraquat-inducible protein A; Region: PqiA; pfam04403
511145003028	paraquat-inducible protein B; Provisional; Region: PRK10807
511145003029	mce related protein; Region: MCE; pfam02470
511145003030	mce related protein; Region: MCE; pfam02470
511145003031	mce related protein; Region: MCE; pfam02470
511145003032	DASH complex subunit Duo1; Region: DASH_Duo1; pfam08651
511145003033	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3009
511145003034	ribosome modulation factor; Provisional; Region: PRK14563
511145003035	FabA, beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase: Bacterial protein of the type II, fatty acid synthase system that binds ACP and catalyzes both dehydration and isomerization reactions, apparently in the same active site. The FabA...; Region: FabA; cd01287
511145003036	active site 1 [active]
511145003037	dimer interface [polypeptide binding]; other site
511145003038	active site 2 [active]
511145003039	Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones]; Region: LonB; COG1067
511145003040	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
511145003041	Ter macrodomain organizer matS-binding protein; Provisional; Region: PRK05097
511145003042	outer membrane protein A; Reviewed; Region: PRK10808
511145003043	OmpA-like transmembrane domain; Region: OmpA_membrane; pfam01389
511145003044	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
511145003045	ligand binding site [chemical binding]; other site
511145003046	cell division inhibitor SulA; Region: sula; TIGR00623
511145003047	Regulator of competence-specific genes [Transcription]; Region: TfoX; COG3070
511145003048	TfoX C-terminal domain; Region: TfoX_C; pfam04994
511145003049	TIGR01666 family membrane protein; Region: YCCS
511145003050	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
511145003051	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
511145003052	Predicted membrane protein [Function unknown]; Region: COG3304
511145003053	Domain of unknown function (DUF307); Region: DUF307; pfam03733
511145003054	Domain of unknown function (DUF307); Region: DUF307; pfam03733
511145003055	DNA helicase IV; Provisional; Region: helD; PRK11054
511145003056	DNA helicase IV / RNA helicase N terminal; Region: Helicase_IV_N; pfam12462
511145003057	Part of AAA domain; Region: AAA_19; pfam13245
511145003058	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
511145003059	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
511145003060	active site
511145003061	dimer interfaces [polypeptide binding]; other site
511145003062	catalytic residues [active]
511145003063	hypothetical protein; Provisional; Region: PRK03641
511145003064	Predicted CoA-binding protein [General function prediction only]; Region: COG1832
511145003065	heat shock protein HspQ; Provisional; Region: PRK14129
511145003066	23S rRNA m(5)C1962 methyltransferase; Provisional; Region: PRK15128
511145003067	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase; Region: PUA; smart00359
511145003068	Middle domain of the SAM-dependent methyltransferase RlmI and related proteins; Region: RlmI_M_like; cd11572
511145003069	putative RNA binding site [nucleotide binding]; other site
511145003070	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145003071	S-adenosylmethionine binding site [chemical binding]; other site
511145003072	Acylphosphatase; Region: Acylphosphatase; cl00551
511145003073	sulfur transfer protein TusE; Provisional; Region: PRK11508
511145003074	YccA-like proteins; Region: YccA_like; cd10433
511145003075	hydrogenase (NiFe) small subunit (hydA); Region: hydA; TIGR00391
511145003076	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
511145003077	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
511145003078	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
511145003079	hydrogenase 1 large subunit; Provisional; Region: PRK10170
511145003080	hydrogenase 1 b-type cytochrome subunit; Provisional; Region: PRK10171
511145003081	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
511145003082	putative substrate-binding site; other site
511145003083	nickel binding site [ion binding]; other site
511145003084	HyaE family; HyaE is also called HupG and HoxO. They are proteins serving a critical role in the assembly of multimeric [NiFe] hydrogenases, the enzymes that catalyze the oxidation of molecular hydrogen to enable microorganisms to utilize hydrogen as the...; Region: HyaE; cd02965
511145003085	HupH hydrogenase expression protein, C-terminal conserved region; Region: HupH_C; pfam04809
511145003086	cytochrome bd-II oxidase subunit 1; Provisional; Region: PRK15035
511145003087	cytochrome bd-II oxidase subunit 2; Provisional; Region: PRK15028
511145003088	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
511145003089	hypothetical protein; Provisional; Region: PRK14749
511145003090	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
511145003091	catalytic core [active]
511145003092	cryptic autophosphorylating protein tyrosine kinase Etk; Provisional; Region: PRK09841
511145003093	Chain length determinant protein; Region: Wzz; pfam02706
511145003094	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145003095	AAA domain; Region: AAA_31; pfam13614
511145003096	Low molecular weight phosphatase family; Region: LMWPc; cd00115
511145003097	active site
511145003098	polysaccharide export protein Wza; Provisional; Region: PRK15078
511145003099	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
511145003100	SLBB domain; Region: SLBB; pfam10531
511145003101	SLBB domain; Region: SLBB; pfam10531
511145003102	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
511145003103	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
511145003104	Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102
511145003105	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145003106	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145003107	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145003108	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145003109	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145003110	DNA-binding site [nucleotide binding]; DNA binding site
511145003111	RNA-binding motif; other site
511145003112	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145003113	DNA-binding site [nucleotide binding]; DNA binding site
511145003114	RNA-binding motif; other site
511145003115	cold shock gene; Provisional; Region: PRK09891
511145003116	GnsA/GnsB family; Region: GnsAB; pfam08178
511145003117	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
511145003118	4Fe-4S binding domain; Region: Fer4_5; pfam12801
511145003119	4Fe-4S binding domain; Region: Fer4_5; pfam12801
511145003120	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145003121	hybrid sensory histidine kinase TorS; Provisional; Region: PRK11466
511145003122	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145003123	dimerization interface [polypeptide binding]; other site
511145003124	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145003125	dimer interface [polypeptide binding]; other site
511145003126	phosphorylation site [posttranslational modification]
511145003127	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145003128	ATP binding site [chemical binding]; other site
511145003129	Mg2+ binding site [ion binding]; other site
511145003130	G-X-G motif; other site
511145003131	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145003132	active site
511145003133	phosphorylation site [posttranslational modification]
511145003134	intermolecular recognition site; other site
511145003135	dimerization interface [polypeptide binding]; other site
511145003136	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145003137	putative binding surface; other site
511145003138	active site
511145003139	TMAO reductase system periplasmic protein TorT; Provisional; Region: PRK10936
511145003140	TorT-like proteins, a periplasmic binding protein family that activates induction of the Tor respiratory system upon trimethylamine N-oxide (TMAO) electron-acceptor binding in bacteria; Region: PBP1_TorT-like; cd06306
511145003141	putative ligand binding site [chemical binding]; other site
511145003142	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
511145003143	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145003144	active site
511145003145	phosphorylation site [posttranslational modification]
511145003146	intermolecular recognition site; other site
511145003147	dimerization interface [polypeptide binding]; other site
511145003148	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145003149	DNA binding site [nucleotide binding]
511145003150	trimethylamine N-oxide reductase cytochrome c-type subunit; Provisional; Region: PRK15032
511145003151	Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit [Energy production and conversion]; Region: TorC; COG3005
511145003152	trimethylamine N-oxide reductase I catalytic subunit; Provisional; Region: PRK15102
511145003153	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
511145003154	molybdopterin cofactor binding site [chemical binding]; other site
511145003155	substrate binding site [chemical binding]; other site
511145003156	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
511145003157	molybdopterin cofactor binding site; other site
511145003158	chaperone protein TorD; Validated; Region: torD; PRK04976
511145003159	chaperone-modulator protein CbpM; Provisional; Region: PRK10265
511145003160	curved DNA-binding protein CbpA; Provisional; Region: PRK10266
511145003161	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
511145003162	HSP70 interaction site [polypeptide binding]; other site
511145003163	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
511145003164	substrate binding site [polypeptide binding]; other site
511145003165	dimer interface [polypeptide binding]; other site
511145003166	hypothetical protein; Provisional; Region: PRK09784
511145003167	Histidine phosphatase domain found in histidine acid phosphatases and phytases; contains a His residue which is phosphorylated during the reaction; Region: HP_HAP_like; cd07061
511145003168	catalytic core [active]
511145003169	hypothetical protein; Provisional; Region: PRK10174
511145003170	NAD(P)H:quinone oxidoreductase; Provisional; Region: PRK03767
511145003171	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
511145003172	General stress protein [General function prediction only]; Region: GsiB; COG3729
511145003173	pyrimidine utilization transport protein G; Region: RutG; TIGR03616
511145003174	uracil-xanthine permease; Region: ncs2; TIGR00801
511145003175	pyrimidine utilization flavin reductase protein F; Region: RutF; TIGR03615
511145003176	Nitroreductase-like family 5.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_5; cd02148
511145003177	putative FMN binding site [chemical binding]; other site
511145003178	pyrimidine utilization protein D; Region: RutD; TIGR03611
511145003179	Putative lysophospholipase; Region: Hydrolase_4; cl19140
511145003180	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
511145003181	homotrimer interaction site [polypeptide binding]; other site
511145003182	putative active site [active]
511145003183	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
511145003184	catalytic triad [active]
511145003185	conserved cis-peptide bond; other site
511145003186	Alkanesulfonate monoxygenase is the monoxygenase of a two-component system that catalyzes the conversion of alkanesulfonates to the corresponding aldehyde and sulfite. Alkanesulfonate monoxygenase (SsuD) has an absolute requirement for reduced flavin...; Region: Alkanesulfonate_monoxygenase; cd01094
511145003187	active site
511145003188	dimer interface [polypeptide binding]; other site
511145003189	non-prolyl cis peptide bond; other site
511145003190	insertion regions; other site
511145003191	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
511145003192	HTH-type transcriptional regulator RutR; Provisional; Region: PRK15008
511145003193	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145003194	YcdC-like protein, C-terminal region; Region: TetR_C_3; pfam08362
511145003195	trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Reviewed; Region: putA; PRK11809
511145003196	Predicted transcriptional regulator [Transcription]; Region: COG3905
511145003197	DNA-binding domain of Proline dehydrogenase; Region: Pro_dh-DNA_bdg; pfam14850
511145003198	Proline dehydrogenase; Region: Pro_dh; pfam01619
511145003199	Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA; Region: ALDH_PutA-P5CDH; cd07125
511145003200	Glutamate binding site [chemical binding]; other site
511145003201	NAD binding site [chemical binding]; other site
511145003202	catalytic residues [active]
511145003203	NAD(P)+-dependent aldehyde dehydrogenase superfamily; Region: ALDH-SF; cl11961
511145003204	Na(+)/proline cotransporter PutP and related proteins; solute binding domain; Region: SLC5sbd_PutP; cd11475
511145003205	Na binding site [ion binding]; other site
511145003206	inactive ferrous ion transporter periplasmic protein EfeO; Provisional; Region: PRK10378
511145003207	Cupredoxin-like domain; Region: Cupredoxin_1; pfam13473
511145003208	Imelysin; Region: Peptidase_M75; pfam09375
511145003209	Tat-translocated enzyme; Region: tat_substr_1; TIGR01412
511145003210	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
511145003211	hypothetical protein; Provisional; Region: PRK10536
511145003212	putative PGA biosynthesis protein; Provisional; Region: pgaD; PRK14585
511145003213	N-glycosyltransferase; Provisional; Region: PRK11204
511145003214	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
511145003215	DXD motif; other site
511145003216	outer membrane N-deacetylase; Provisional; Region: pgaB; PRK14582
511145003217	N-terminal putative catalytic polysaccharide deacetylase domain of bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, and similar proteins; Region: CE4_PgaB_5s; cd10964
511145003218	putative active site [active]
511145003219	putative metal binding site [ion binding]; other site
511145003220	Hypothetical glycosyl hydrolase family 13; Region: GHL13; pfam14883
511145003221	outer membrane protein PgaA; Provisional; Region: pgaA; PRK10049
511145003222	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145003223	metal binding site [ion binding]; metal-binding site
511145003224	active site
511145003225	I-site; other site
511145003226	putative transposase OrfB; Reviewed; Region: PHA02517
511145003227	HTH-like domain; Region: HTH_21; pfam13276
511145003228	Integrase core domain; Region: rve; pfam00665
511145003229	Integrase core domain; Region: rve_2; pfam13333
511145003230	Transposase; Region: HTH_Tnp_1; cl17663
511145003231	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145003232	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
511145003233	Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family; Region: GDH_like_2; cd12164
511145003234	putative ligand binding site [chemical binding]; other site
511145003235	NAD binding site [chemical binding]; other site
511145003236	dimerization interface [polypeptide binding]; other site
511145003237	catalytic site [active]
511145003238	putative hydrolase; Validated; Region: PRK09248
511145003239	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
511145003240	active site
511145003241	Uncharacterized component of anaerobic dehydrogenases [General function prediction only]; Region: TorD; COG3381
511145003242	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
511145003243	curli production assembly/transport protein CsgG; Provisional; Region: PRK15184
511145003244	curli assembly protein CsgF; Provisional; Region: PRK10050
511145003245	curli assembly protein CsgE; Provisional; Region: PRK10386
511145003246	DNA-binding transcriptional regulator CsgD; Provisional; Region: PRK10100
511145003247	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145003248	DNA binding residues [nucleotide binding]
511145003249	dimerization interface [polypeptide binding]; other site
511145003250	curlin minor subunit CsgB; Provisional; Region: csgB; PRK10101
511145003251	Curlin associated repeat; Region: Curlin_rpt; pfam07012
511145003252	Curlin associated repeat; Region: Curlin_rpt; pfam07012
511145003253	major curlin subunit; Provisional; Region: csgA; PRK10051
511145003254	Thin aggregative fimbriae synthesis protein; Region: Tafi-CsgC; pfam10610
511145003255	Fimbrial protein; Region: Fimbrial; cl01416
511145003256	Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly...; Region: Macro_Appr_pase_like; cd02908
511145003257	putative ADP-ribose binding site [chemical binding]; other site
511145003258	putative active site [active]
511145003259	Putative catalytic domain, repeat 1, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_1; cd09111
511145003260	PLD-like domain; Region: PLDc_2; pfam13091
511145003261	putative active site [active]
511145003262	catalytic site [active]
511145003263	Putative catalytic domain, repeat 2, of Escherichia coli uncharacterized protein ymdC and similar proteins; Region: PLDc_ymdC_like_2; cd09113
511145003264	PLD-like domain; Region: PLDc_2; pfam13091
511145003265	putative active site [active]
511145003266	catalytic site [active]
511145003267	glucans biosynthesis protein; Provisional; Region: opgC; PRK03854
511145003268	glucan biosynthesis protein G; Provisional; Region: mdoG; PRK13274
511145003269	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
511145003270	Glucan_BSP_ModH catalyzes the elongation of beta-1,2 polyglucose chains of glucan; Region: Glucan_BSP_ModH; cd04191
511145003271	Ligand binding site; other site
511145003272	DXD motif; other site
511145003273	lipoprotein; Provisional; Region: PRK10175
511145003274	secY/secA suppressor protein; Provisional; Region: PRK11467
511145003275	drug efflux system protein MdtG; Provisional; Region: PRK09874
511145003276	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145003277	putative substrate translocation pore; other site
511145003278	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
511145003279	putative acyl-acceptor binding pocket; other site
511145003280	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
511145003281	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
511145003282	active site residue [active]
511145003283	hypothetical protein; Provisional; Region: PRK03757
511145003284	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
511145003285	Protein of unknown function (DUF2770); Region: DUF2770; pfam10968
511145003286	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
511145003287	N-methyltryptophan oxidase; Provisional; Region: solA; PRK11259
511145003288	biofilm formation regulatory protein BssS; Reviewed; Region: bssS; PRK12301
511145003289	DNA damage-inducible protein I; Provisional; Region: PRK10597
511145003290	Dihydroorotase (DHOase) catalyzes the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in the pyrimidine biosynthesis. In contrast to the large polyfunctional CAD proteins of higher organisms, this group of DHOases is...; Region: DHOase; cd01294
511145003291	active site
511145003292	substrate binding pocket [chemical binding]; other site
511145003293	dimer interface [polypeptide binding]; other site
511145003294	lipoprotein; Provisional; Region: PRK10598
511145003295	glutaredoxin 2; Provisional; Region: PRK10387
511145003296	GST_N family, Glutaredoxin 2 (GRX2) subfamily; composed of bacterial proteins similar to E. coli GRX2, an atypical GRX with a molecular mass of about 24kD, compared with other GRXs which are 9-12kD in size. GRX2 adopts a GST fold containing an N-terminal...; Region: GST_N_GRX2; cd03037
511145003297	C-terminal domain interface [polypeptide binding]; other site
511145003298	GSH binding site (G-site) [chemical binding]; other site
511145003299	catalytic residues [active]
511145003300	putative dimer interface [polypeptide binding]; other site
511145003301	C-terminal, alpha helical domain of Glutaredoxin 2; Region: GST_C_GRX2; cd03199
511145003302	N-terminal domain interface [polypeptide binding]; other site
511145003303	multidrug resistance protein MdtH; Provisional; Region: PRK11646
511145003304	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145003305	putative substrate translocation pore; other site
511145003306	ribosomal-protein-S5-alanine N-acetyltransferase; Provisional; Region: PRK10809
511145003307	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
511145003308	hypothetical protein; Provisional; Region: PRK11239
511145003309	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
511145003310	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145003311	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145003312	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
511145003313	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
511145003314	flagella synthesis chaperone protein FlgN; Provisional; Region: PRK15459
511145003315	anti-sigma28 factor FlgM; Provisional; Region: PRK10810
511145003316	SAF domains of the flagella basal body P-ring formation protein FlgA and the flp pilus assembly CpaB; Region: SAF_CpaB_FlgA_like; cd11614
511145003317	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
511145003318	flagellar basal body rod protein FlgB; Reviewed; Region: flgB; PRK05680
511145003319	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
511145003320	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
511145003321	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
511145003322	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
511145003323	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06655
511145003324	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
511145003325	FlgD Tudor-like domain; Region: FLgD_tudor; pfam13861
511145003326	flagellar hook protein FlgE; Validated; Region: flgE; PRK05682
511145003327	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
511145003328	Flagellar basal body protein FlaE; Region: FlaE; pfam07559
511145003329	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
511145003330	Flagellar basal body rod protein [Cell motility and secretion]; Region: FlgF; COG4787
511145003331	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
511145003332	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
511145003333	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12693
511145003334	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
511145003335	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
511145003336	flagellar basal body L-ring protein; Reviewed; Region: flgH; PRK00249
511145003337	flagellar basal body P-ring protein; Provisional; Region: flgI; PRK05303
511145003338	flagellar rod assembly protein/muramidase FlgJ; Validated; Region: flgJ; PRK05684
511145003339	Rod binding protein [Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones]; Region: COG3951
511145003340	Muramidase (flagellum-specific) [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FlgJ; COG1705
511145003341	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK08147
511145003342	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
511145003343	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
511145003344	flagellar hook-associated protein FlgL; Reviewed; Region: flgL; PRK08027
511145003345	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
511145003346	ribonuclease E; Reviewed; Region: rne; PRK10811
511145003347	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
511145003348	homodimer interface [polypeptide binding]; other site
511145003349	oligonucleotide binding site [chemical binding]; other site
511145003350	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
511145003351	Polyribonucleotide phosphorylase C terminal; Region: PNPase_C; pfam12111
511145003352	Protein of unknown function (DUF2655); Region: DUF2655; pfam10848
511145003353	23S rRNA pseudouridylate synthase C; Provisional; Region: PRK11025
511145003354	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145003355	RNA binding surface [nucleotide binding]; other site
511145003356	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
511145003357	active site
511145003358	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
511145003359	active site
511145003360	dimer interface [polypeptide binding]; other site
511145003361	hypothetical protein; Provisional; Region: PRK11193
511145003362	50S ribosomal protein L32; Validated; Region: rpmF; PRK01110
511145003363	putative phosphate acyltransferase; Provisional; Region: PRK05331
511145003364	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
511145003365	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
511145003366	dimer interface [polypeptide binding]; other site
511145003367	active site
511145003368	CoA binding pocket [chemical binding]; other site
511145003369	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
511145003370	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
511145003371	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
511145003372	NAD(P) binding site [chemical binding]; other site
511145003373	homotetramer interface [polypeptide binding]; other site
511145003374	homodimer interface [polypeptide binding]; other site
511145003375	active site
511145003376	acyl carrier protein; Provisional; Region: acpP; PRK00982
511145003377	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK07314
511145003378	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
511145003379	dimer interface [polypeptide binding]; other site
511145003380	active site
511145003381	ADCL_like: 4-Amino-4-deoxychorismate lyase:  is a member of the fold-type IV of PLP dependent enzymes that converts 4-amino-4-deoxychorismate (ADC) to p-aminobenzoate and pyruvate.  Based on the information available from the crystal structure, most...; Region: ADCL_like; cd01559
511145003382	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145003383	catalytic residue [active]
511145003384	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
511145003385	dimerization interface [polypeptide binding]; other site
511145003386	thymidylate kinase; Validated; Region: tmk; PRK00698
511145003387	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
511145003388	TMP-binding site; other site
511145003389	ATP-binding site [chemical binding]; other site
511145003390	DNA polymerase III subunit delta'; Validated; Region: PRK07993
511145003391	DNA polymerase III, delta subunit, C terminal; Region: DNApol3-delta_C; pfam09115
511145003392	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
511145003393	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
511145003394	active site
511145003395	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
511145003396	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
511145003397	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145003398	active site turn [active]
511145003399	phosphorylation site [posttranslational modification]
511145003400	ferric-rhodotorulic acid outer membrane transporter; Provisional; Region: PRK10003
511145003401	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145003402	N-terminal plug; other site
511145003403	ligand-binding site [chemical binding]; other site
511145003404	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
511145003405	nucleotide binding site/active site [active]
511145003406	HIT family signature motif; other site
511145003407	catalytic residue [active]
511145003408	Putative periplasmic lipoprotein; Region: DUF1425; cd09030
511145003409	putative dimer interface [polypeptide binding]; other site
511145003410	Collagen-binding surface adhesin SpaP (antigen I/II family) [General function prediction only]; Region: FlgN; COG3417
511145003411	thiamine kinase; Region: ycfN_thiK; TIGR02721
511145003412	Phosphotransferase enzyme family; Region: APH; pfam01636
511145003413	active site
511145003414	substrate binding site [chemical binding]; other site
511145003415	ATP binding site [chemical binding]; other site
511145003416	beta-hexosaminidase; Provisional; Region: PRK05337
511145003417	hypothetical protein; Provisional; Region: PRK04940
511145003418	NADH dehydrogenase, FAD-containing subunit [Energy production and conversion]; Region: Ndh; COG1252
511145003419	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145003420	hypothetical protein; Provisional; Region: PRK11280
511145003421	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
511145003422	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145003423	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145003424	L,D-transpeptidase; Provisional; Region: PRK10260
511145003425	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145003426	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145003427	transcription-repair coupling factor; Provisional; Region: PRK10689
511145003428	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
511145003429	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
511145003430	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145003431	ATP binding site [chemical binding]; other site
511145003432	putative Mg++ binding site [ion binding]; other site
511145003433	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145003434	nucleotide binding region [chemical binding]; other site
511145003435	ATP-binding site [chemical binding]; other site
511145003436	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
511145003437	Predicted membrane protein [Function unknown]; Region: COG4763
511145003438	outer membrane-specific lipoprotein transporter subunit LolC; Provisional; Region: PRK10814
511145003439	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
511145003440	FtsX-like permease family; Region: FtsX; pfam02687
511145003441	lipoprotein transporter ATP-binding subunit; Provisional; Region: lolD; PRK11629
511145003442	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
511145003443	Walker A/P-loop; other site
511145003444	ATP binding site [chemical binding]; other site
511145003445	Q-loop/lid; other site
511145003446	ABC transporter signature motif; other site
511145003447	Walker B; other site
511145003448	D-loop; other site
511145003449	H-loop/switch region; other site
511145003450	outer membrane-specific lipoprotein transporter subunit LolE; Provisional; Region: PRK11146
511145003451	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
511145003452	FtsX-like permease family; Region: FtsX; pfam02687
511145003453	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145003454	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145003455	nucleotide binding site [chemical binding]; other site
511145003456	SIRT5_Af1_CobB: Eukaryotic, archaeal and prokaryotic group (class3) which includes human sirtuin SIRT5, Archaeoglobus fulgidus Sir2-Af1, and E. coli CobB; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which...; Region: SIRT5_Af1_CobB; cd01412
511145003457	NAD+ binding site [chemical binding]; other site
511145003458	substrate binding site [chemical binding]; other site
511145003459	Zn binding site [ion binding]; other site
511145003460	TLP18.3, Psb32 and MOLO-1 founding proteins of phosphatase; Region: TPM; cl01535
511145003461	Protein of unknown function (DUF3592); Region: DUF3592; pfam12158
511145003462	spermidine/putrescine ABC transporter periplasmic substrate-binding protein; Reviewed; Region: potD; PRK09501
511145003463	spermidine/putrescine ABC transporter membrane protein; Reviewed; Region: potC; PRK09500
511145003464	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003465	dimer interface [polypeptide binding]; other site
511145003466	conserved gate region; other site
511145003467	putative PBP binding loops; other site
511145003468	ABC-ATPase subunit interface; other site
511145003469	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
511145003470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003471	dimer interface [polypeptide binding]; other site
511145003472	conserved gate region; other site
511145003473	putative PBP binding loops; other site
511145003474	ABC-ATPase subunit interface; other site
511145003475	putrescine/spermidine ABC transporter ATPase protein; Reviewed; Region: potA; PRK09452
511145003476	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
511145003477	Walker A/P-loop; other site
511145003478	ATP binding site [chemical binding]; other site
511145003479	Q-loop/lid; other site
511145003480	ABC transporter signature motif; other site
511145003481	Walker B; other site
511145003482	D-loop; other site
511145003483	H-loop/switch region; other site
511145003484	TOBE domain; Region: TOBE_2; pfam08402
511145003485	peptidase T-like protein; Region: PepT-like; TIGR01883
511145003486	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
511145003487	metal binding site [ion binding]; metal-binding site
511145003488	dimer interface [polypeptide binding]; other site
511145003489	Uncharacterized conserved protein [Function unknown]; Region: COG2850
511145003490	sensor protein PhoQ; Provisional; Region: PRK10815
511145003491	PhoQ Sensor; Region: PhoQ_Sensor; pfam08918
511145003492	HAMP domain; Region: HAMP; pfam00672
511145003493	His Kinase A (phospho-acceptor) domain; Region: HisKA; pfam00512
511145003494	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145003495	ATP binding site [chemical binding]; other site
511145003496	Mg2+ binding site [ion binding]; other site
511145003497	G-X-G motif; other site
511145003498	DNA-binding transcriptional regulator PhoP; Provisional; Region: PRK10816
511145003499	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145003500	active site
511145003501	phosphorylation site [posttranslational modification]
511145003502	intermolecular recognition site; other site
511145003503	dimerization interface [polypeptide binding]; other site
511145003504	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145003505	DNA binding site [nucleotide binding]
511145003506	adenylosuccinate lyase; Provisional; Region: PRK09285
511145003507	PurB_like adenylosuccinases (adenylsuccinate lyase, ASL); Region: PurB; cd01598
511145003508	tetramer interface [polypeptide binding]; other site
511145003509	active site
511145003510	putative lysogenization regulator; Reviewed; Region: PRK00218
511145003511	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Region: trmU; TIGR00420
511145003512	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
511145003513	Ligand Binding Site [chemical binding]; other site
511145003514	Contains a crystal structure of the Nudix hydrolase from Nitrosomonas europaea, which has an unknown function. In general, members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes...; Region: Nudix_Hydrolase_2; cd03675
511145003515	nudix motif; other site
511145003516	23S rRNA pseudouridine synthase E; Provisional; Region: PRK11394
511145003517	Pseudouridine synthase, Escherichia coli RluE; Region: PseudoU_synth_RluE; cd02566
511145003518	probable active site [active]
511145003519	isocitrate dehydrogenase; Reviewed; Region: PRK07006
511145003520	cryptic prophage e14
511145003521	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145003522	S-adenosylmethionine binding site [chemical binding]; other site
511145003523	phage exclusion protein Lit; Provisional; Region: PRK09672
511145003524	Bacteriophage lambda integrase, N-terminal domain; Region: Phage_integ_N; pfam09003
511145003525	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
511145003526	Lambda integrase, C-terminal catalytic domain. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome.  They belong to the superfamily...; Region: INT_Lambda_C; cd00800
511145003527	dimer interface [polypeptide binding]; other site
511145003528	active site
511145003529	Int/Topo IB signature motif; other site
511145003530	Excisionase-like protein; Region: Exc; pfam07825
511145003531	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
511145003532	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
511145003533	Catalytic site [active]
511145003534	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3778
511145003535	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
511145003536	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
511145003537	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
511145003538	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
511145003539	catalytic residues [active]
511145003540	catalytic nucleophile [active]
511145003541	Presynaptic Site I dimer interface [polypeptide binding]; other site
511145003542	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
511145003543	Synaptic Flat tetramer interface [polypeptide binding]; other site
511145003544	Synaptic Site I dimer interface [polypeptide binding]; other site
511145003545	DNA binding site [nucleotide binding]
511145003546	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
511145003547	DNA-binding interface [nucleotide binding]; DNA binding site
511145003548	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
511145003549	active site
511145003550	anti-adapter protein IraM; Provisional; Region: PRK09919
511145003551	Phage envelope protein [General function prediction only]; Region: COG5562
511145003552	transcriptional regulator MirA; Provisional; Region: PRK15043
511145003553	Helix-Turn-Helix DNA binding domain of the transcription regulators MlrA and CarA; Region: HTH_MlrA-CarA; cd01104
511145003554	DNA binding residues [nucleotide binding]
511145003555	Sensors of blue-light using FAD; Region: BLUF; smart01034
511145003556	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145003557	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
511145003558	Biofilm development protein YmgB/AriR; Region: YmgB; pfam10798
511145003559	phage resistance protein; Provisional; Region: PRK10551
511145003560	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
511145003561	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145003562	Glycine-zipper containing OmpA-like membrane domain; Region: Gly-zipper_OmpA; pfam13436
511145003563	cell division topological specificity factor MinE; Reviewed; Region: minE; PRK00296
511145003564	cell division inhibitor MinD; Provisional; Region: PRK10818
511145003565	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
511145003566	P-loop; other site
511145003567	ADP binding residues [chemical binding]; other site
511145003568	Switch I; other site
511145003569	Switch II; other site
511145003570	septum formation inhibitor; Reviewed; Region: minC; PRK03511
511145003571	Septum formation inhibitor MinC, N-terminal domain; Region: MinC_N; pfam05209
511145003572	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
511145003573	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
511145003574	Fels-1 Prophage Protein-like; Region: Fels1; pfam05666
511145003575	Bacterial pre-peptidase C-terminal domain; Region: PPC; pfam04151
511145003576	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3100
511145003577	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
511145003578	hypothetical protein; Provisional; Region: PRK10691
511145003579	hypothetical protein; Provisional; Region: PRK05170
511145003580	Haemolysin E (HlyE); Region: HlyE; pfam06109
511145003581	SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms]; Region: LexA; COG1974
511145003582	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
511145003583	Catalytic site [active]
511145003584	DNA polymerase V subunit UmuC; Reviewed; Region: umuC; PRK03609
511145003585	umuC subunit of DNA Polymerase V; Region: PolY_Pol_V_umuC; cd01700
511145003586	active site
511145003587	DNA binding site [nucleotide binding]
511145003588	Domain of unknown function (DUF4113); Region: DUF4113; pfam13438
511145003589	disulfide bond formation protein B; Provisional; Region: PRK01749
511145003590	sodium/proton antiporter; Reviewed; Region: nhaB; PRK09547
511145003591	fatty acid metabolism regulator; Provisional; Region: PRK04984
511145003592	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145003593	DNA-binding site [nucleotide binding]; DNA binding site
511145003594	FadR C-terminal domain; Region: FadR_C; pfam07840
511145003595	SpoVR family protein; Provisional; Region: PRK11767
511145003596	D-amino acid dehydrogenase small subunit; Validated; Region: PRK00711
511145003597	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145003598	alanine racemase; Reviewed; Region: dadX; PRK03646
511145003599	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
511145003600	active site
511145003601	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145003602	substrate binding site [chemical binding]; other site
511145003603	catalytic residues [active]
511145003604	dimer interface [polypeptide binding]; other site
511145003605	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
511145003606	NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain [Inorganic ion transport and metabolism]; Region: COG3263
511145003607	TrkA-C domain; Region: TrkA_C; pfam02080
511145003608	Transporter associated domain; Region: CorC_HlyC; smart01091
511145003609	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
511145003610	dimer interface [polypeptide binding]; other site
511145003611	catalytic triad [active]
511145003612	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145003613	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145003614	catalytic residue [active]
511145003615	c-di-GMP-binding protein [Signal transduction mechanisms]; Region: COG5581
511145003616	Flagellar regulator YcgR; Region: YcgR; pfam07317
511145003617	PilZ domain; Region: PilZ; pfam07238
511145003618	Transglycosylase associated protein; Region: Transgly_assoc; cl00978
511145003619	trehalase; Provisional; Region: treA; PRK13271
511145003620	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
511145003621	dihydroxyacetone kinase subunit M; Provisional; Region: PRK11377
511145003622	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3412
511145003623	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145003624	dimerization domain swap beta strand [polypeptide binding]; other site
511145003625	regulatory protein interface [polypeptide binding]; other site
511145003626	active site
511145003627	regulatory phosphorylation site [posttranslational modification]; other site
511145003628	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
511145003629	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145003630	dihydroxyacetone kinase subunit DhaL; Provisional; Region: PRK10005
511145003631	dihydroxyacetone kinase subunit DhaK; Provisional; Region: PRK11468
511145003632	DNA-binding transcriptional regulator DhaR; Provisional; Region: PRK11388
511145003633	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145003634	putative active site [active]
511145003635	heme pocket [chemical binding]; other site
511145003636	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145003637	Walker A motif; other site
511145003638	ATP binding site [chemical binding]; other site
511145003639	Walker B motif; other site
511145003640	arginine finger; other site
511145003641	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145003642	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
511145003643	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
511145003644	Autotransporter beta-domain; Region: Autotransporter; pfam03797
511145003645	GTP-binding protein YchF; Reviewed; Region: PRK09601
511145003646	YchF GTPase; Region: YchF; cd01900
511145003647	G1 box; other site
511145003648	GTP/Mg2+ binding site [chemical binding]; other site
511145003649	Switch I region; other site
511145003650	G2 box; other site
511145003651	Switch II region; other site
511145003652	G3 box; other site
511145003653	G4 box; other site
511145003654	G5 box; other site
511145003655	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
511145003656	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
511145003657	putative active site [active]
511145003658	catalytic residue [active]
511145003659	hypothetical protein; Provisional; Region: PRK10692
511145003660	putative transporter; Provisional; Region: PRK11660
511145003661	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
511145003662	Sulfate transporter family; Region: Sulfate_transp; pfam00916
511145003663	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
511145003664	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
511145003665	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
511145003666	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145003667	active site
511145003668	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00343
511145003669	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
511145003670	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
511145003671	outer membrane lipoprotein LolB; Region: lolB; TIGR00548
511145003672	glutamyl-tRNA reductase; Reviewed; Region: hemA; PRK00045
511145003673	NADP-binding domain of glutamyl-tRNA reductase; Region: NAD_bind_Glutamyl_tRNA_reduct; cd05213
511145003674	tRNA; other site
511145003675	putative tRNA binding site [nucleotide binding]; other site
511145003676	putative NADP binding site [chemical binding]; other site
511145003677	Glutamyl-tRNAGlu reductase, dimerization domain; Region: GlutR_dimer; pfam00745
511145003678	peptide chain release factor 1; Validated; Region: prfA; PRK00591
511145003679	This domain is found in peptide chain release factors; Region: PCRF; smart00937
511145003680	RF-1 domain; Region: RF-1; pfam00472
511145003681	HemK family putative methylases; Region: hemK_fam; TIGR00536
511145003682	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; cl17726
511145003683	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145003684	S-adenosylmethionine binding site [chemical binding]; other site
511145003685	hypothetical protein; Provisional; Region: PRK10278
511145003686	hypothetical protein; Provisional; Region: PRK10941
511145003687	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
511145003688	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
511145003689	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
511145003690	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
511145003691	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
511145003692	calcium/sodium:proton antiporter; Provisional; Region: PRK10599
511145003693	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
511145003694	cation transport regulator; Reviewed; Region: chaB; PRK09582
511145003695	Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism]; Region: ChaC; COG3703
511145003696	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
511145003697	putative active site pocket [active]
511145003698	dimerization interface [polypeptide binding]; other site
511145003699	putative catalytic residue [active]
511145003700	Uncharacterized conserved protein involved in intracellular sulfur reduction [Inorganic ion transport and metabolism]; Region: DsrE; COG1553
511145003701	putative invasin; Provisional; Region: PRK10177
511145003702	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
511145003703	transcriptional regulator NarL; Provisional; Region: PRK10651
511145003704	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145003705	active site
511145003706	phosphorylation site [posttranslational modification]
511145003707	intermolecular recognition site; other site
511145003708	dimerization interface [polypeptide binding]; other site
511145003709	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145003710	DNA binding residues [nucleotide binding]
511145003711	dimerization interface [polypeptide binding]; other site
511145003712	nitrate/nitrite sensor protein NarX; Provisional; Region: PRK10600
511145003713	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
511145003714	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145003715	dimerization interface [polypeptide binding]; other site
511145003716	Histidine kinase; Region: HisKA_3; pfam07730
511145003717	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145003718	ATP binding site [chemical binding]; other site
511145003719	Mg2+ binding site [ion binding]; other site
511145003720	G-X-G motif; other site
511145003721	lysophospholipid transporter LplT; Provisional; Region: PRK11195; cl19150
511145003722	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
511145003723	respiratory nitrate reductase, alpha subunit; Region: narG; TIGR01580
511145003724	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
511145003725	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
511145003726	[4Fe-4S] binding site [ion binding]; other site
511145003727	molybdopterin cofactor binding site [chemical binding]; other site
511145003728	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
511145003729	molybdopterin cofactor binding site; other site
511145003730	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
511145003731	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145003732	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
511145003733	Nitrate reductase delta subunit; Region: Nitrate_red_del; cl00958
511145003734	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
511145003735	putative protamine-like protein; Provisional; Region: PRK14757
511145003736	formyltetrahydrofolate deformylase; Reviewed; Region: purU; PRK06027
511145003737	N-terminal ACT domain of formyltetrahydrofolate deformylase (F4HF-DF; formyltetrahydrofolate hydrolase); Region: ACT_F4HF-DF; cd04875
511145003738	Formyltetrahydrofolate deformylase (Formyl-FH4 hydrolase), C-terminal hydrolase domain; Region: FMT_core_Formyl-FH4-Hydrolase_C; cd08648
511145003739	putative active site [active]
511145003740	putative substrate binding site [chemical binding]; other site
511145003741	putative cosubstrate binding site; other site
511145003742	catalytic site [active]
511145003743	hypothetical protein; Provisional; Region: PRK01617
511145003744	SEC-C motif; Region: SEC-C; cl19389
511145003745	SEC-C motif; Region: SEC-C; cl19389
511145003746	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
511145003747	Bacterial patatin-like phospholipase domain containing protein 6; Region: Pat_NTE_like_bacteria; cd07228
511145003748	active site
511145003749	nucleophile elbow; other site
511145003750	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145003751	active site
511145003752	response regulator of RpoS; Provisional; Region: PRK10693
511145003753	phosphorylation site [posttranslational modification]
511145003754	intermolecular recognition site; other site
511145003755	dimerization interface [polypeptide binding]; other site
511145003756	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
511145003757	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
511145003758	active site
511145003759	tetramer interface; other site
511145003760	global DNA-binding transcriptional dual regulator H-NS; Provisional; Region: PRK10947
511145003761	DNA-binding protein H-NS [General function prediction only]; Region: Hns; COG2916
511145003762	thymidine kinase; Provisional; Region: PRK04296
511145003763	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
511145003764	Coenzyme A acylating aldehyde dehydrogenase (ACDH), Ethanolamine utilization protein EutE, and related proteins; Region: ALDH_F20_ACDH_EutE-like; cd07081
511145003765	putative catalytic cysteine [active]
511145003766	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
511145003767	putative active site [active]
511145003768	metal binding site [ion binding]; metal-binding site
511145003769	hypothetical protein; Provisional; Region: PRK11111
511145003770	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
511145003771	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
511145003772	peptide binding site [polypeptide binding]; other site
511145003773	oligopeptide transporter permease; Reviewed; Region: oppB; PRK09471
511145003774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003775	dimer interface [polypeptide binding]; other site
511145003776	conserved gate region; other site
511145003777	putative PBP binding loops; other site
511145003778	ABC-ATPase subunit interface; other site
511145003779	oligopeptide ABC transporter permease OppC; Provisional; Region: PRK15406
511145003780	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
511145003781	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003782	dimer interface [polypeptide binding]; other site
511145003783	conserved gate region; other site
511145003784	putative PBP binding loops; other site
511145003785	ABC-ATPase subunit interface; other site
511145003786	oligopeptide transporter ATP-binding component; Provisional; Region: oppD; PRK09473
511145003787	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145003788	Walker A/P-loop; other site
511145003789	ATP binding site [chemical binding]; other site
511145003790	Q-loop/lid; other site
511145003791	ABC transporter signature motif; other site
511145003792	Walker B; other site
511145003793	D-loop; other site
511145003794	H-loop/switch region; other site
511145003795	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145003796	oligopeptide ABC transporter ATP-binding protein OppF; Provisional; Region: PRK15079
511145003797	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145003798	Walker A/P-loop; other site
511145003799	ATP binding site [chemical binding]; other site
511145003800	Q-loop/lid; other site
511145003801	ABC transporter signature motif; other site
511145003802	Walker B; other site
511145003803	D-loop; other site
511145003804	H-loop/switch region; other site
511145003805	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145003806	dsDNA-mimic protein; Reviewed; Region: PRK05094
511145003807	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
511145003808	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
511145003809	Catalytic domain, repeat 1, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_1; cd09152
511145003810	putative active site [active]
511145003811	catalytic site [active]
511145003812	Catalytic domain, repeat 2, of Escherichia coli cardiolipin synthase and similar proteins; Region: PLDc_EcCLS_like_2; cd09158
511145003813	putative active site [active]
511145003814	catalytic site [active]
511145003815	voltage-gated potassium channel; Provisional; Region: PRK10537
511145003816	Ion channel; Region: Ion_trans_2; pfam07885
511145003817	TrkA-N domain; Region: TrkA_N; pfam02254
511145003818	YciI-like protein; Reviewed; Region: PRK11370
511145003819	transport protein TonB; Provisional; Region: PRK10819
511145003820	Gram-negative bacterial TonB protein C-terminal; Region: TonB_C; pfam03544
511145003821	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
511145003822	intracellular septation protein A; Reviewed; Region: PRK00259
511145003823	hypothetical protein; Provisional; Region: PRK02868
511145003824	outer membrane protein W; Provisional; Region: PRK10959
511145003825	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3685
511145003826	YciF bacterial stress response protein, ferritin-like iron-binding domain; Region: YciF; cd07909
511145003827	dimerization interface [polypeptide binding]; other site
511145003828	metal binding site [ion binding]; metal-binding site
511145003829	General stress protein [General function prediction only]; Region: GsiB; COG3729
511145003830	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
511145003831	substrate binding site [chemical binding]; other site
511145003832	active site
511145003833	catalytic residues [active]
511145003834	heterodimer interface [polypeptide binding]; other site
511145003835	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
511145003836	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145003837	catalytic residue [active]
511145003838	bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase; Provisional; Region: PRK09522
511145003839	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
511145003840	glutamine binding [chemical binding]; other site
511145003841	catalytic triad [active]
511145003842	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
511145003843	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
511145003844	anthranilate synthase component I; Provisional; Region: PRK13564
511145003845	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
511145003846	chorismate binding enzyme; Region: Chorismate_bind; pfam00425
511145003847	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
511145003848	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
511145003849	active site
511145003850	hypothetical protein; Provisional; Region: PRK11630
511145003851	Predicted membrane protein (DUF2207); Region: DUF2207; pfam09972
511145003852	23S rRNA pseudouridylate synthase B; Provisional; Region: PRK10700
511145003853	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145003854	RNA binding surface [nucleotide binding]; other site
511145003855	Pseudouridine synthase, Escherichia coli RluB like; Region: PseudoU_synth_RluB; cd02556
511145003856	probable active site [active]
511145003857	ATP:corrinoid adenosyltransferase [Coenzyme metabolism]; Region: BtuR; COG2109
511145003858	Cob(I)alamin adenosyltransferase N terminal; Region: Co_AT_N; pfam12557
511145003859	ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin (vitamin B12) adenosyltransferase, which is involved in cobalamin (vitamin B12) biosynthesis. This enzyme is a homodimer; Region: CobA_CobO_BtuR; cd00561
511145003860	homodimer interface [polypeptide binding]; other site
511145003861	Walker A motif; other site
511145003862	ATP binding site [chemical binding]; other site
511145003863	hydroxycobalamin binding site [chemical binding]; other site
511145003864	Walker B motif; other site
511145003865	Escherichia coli K-12 YCIK-like, classical (c) SDRs; Region: Ycik_SDR_c; cd05340
511145003866	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
511145003867	NADP binding site [chemical binding]; other site
511145003868	homodimer interface [polypeptide binding]; other site
511145003869	active site
511145003870	Peptidase family S49 N-terminal; Region: Peptidase_S49_N; pfam08496
511145003871	putative inner membrane peptidase; Provisional; Region: PRK11778
511145003872	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
511145003873	tandem repeat interface [polypeptide binding]; other site
511145003874	oligomer interface [polypeptide binding]; other site
511145003875	active site residues [active]
511145003876	hypothetical protein; Provisional; Region: PRK11037
511145003877	DNA topoisomerase I subunit omega; Validated; Region: PRK07561
511145003878	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
511145003879	active site
511145003880	interdomain interaction site; other site
511145003881	putative metal-binding site [ion binding]; other site
511145003882	nucleotide binding site [chemical binding]; other site
511145003883	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
511145003884	domain I; other site
511145003885	DNA binding groove [nucleotide binding]
511145003886	phosphate binding site [ion binding]; other site
511145003887	domain II; other site
511145003888	domain III; other site
511145003889	nucleotide binding site [chemical binding]; other site
511145003890	catalytic site [active]
511145003891	domain IV; other site
511145003892	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
511145003893	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
511145003894	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
511145003895	Topoisomerase I zinc-ribbon-like; Region: Topo_Zn_Ribbon; pfam08272
511145003896	transcriptional regulator CysB; Reviewed; Region: cysB; PRK12681
511145003897	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145003898	The C-terminal substrate domain of LysR-type transcriptional regulator CysB contains type 2 periplasmic binding fold; Region: PBP2_CysB; cd08443
511145003899	substrate binding site [chemical binding]; other site
511145003900	putative dimerization interface [polypeptide binding]; other site
511145003901	aconitate hydratase; Validated; Region: PRK09277
511145003902	Aconitase A catalytic domain; Region: AcnA_IRP; cd01586
511145003903	substrate binding site [chemical binding]; other site
511145003904	ligand binding site [chemical binding]; other site
511145003905	Aconitase A swivel domain. This is the major form of the TCA cycle enzyme aconitate hydratase, also known as aconitase and citrate hydro-lyase. It includes bacterial and archaeal aconitase A, and the eukaryotic cytosolic form of aconitase. This group...; Region: AcnA_IRP_Swivel; cd01580
511145003906	substrate binding site [chemical binding]; other site
511145003907	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
511145003908	dimerization interface [polypeptide binding]; other site
511145003909	active site
511145003910	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
511145003911	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
511145003912	active site
511145003913	Predicted membrane protein [Function unknown]; Region: COG3771
511145003914	Predicted N-acetylglucosaminyl transferase [Carbohydrate transport and metabolism]; Region: COG2956
511145003915	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145003916	TPR motif; other site
511145003917	binding surface
511145003918	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145003919	binding surface
511145003920	TPR motif; other site
511145003921	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
511145003922	active site
511145003923	dimer interface [polypeptide binding]; other site
511145003924	Homologs of eIF1/SUI1 including Escherichia coli YciH; Region: YciH_like; cd11567
511145003925	putative rRNA binding site [nucleotide binding]; other site
511145003926	lipoprotein; Provisional; Region: PRK10540
511145003927	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
511145003928	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
511145003929	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145003930	hypothetical protein; Provisional; Region: PRK13658
511145003931	RNase II stability modulator; Provisional; Region: PRK10060
511145003932	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145003933	putative active site [active]
511145003934	heme pocket [chemical binding]; other site
511145003935	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145003936	metal binding site [ion binding]; metal-binding site
511145003937	active site
511145003938	I-site; other site
511145003939	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145003940	exoribonuclease II; Provisional; Region: PRK05054
511145003941	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
511145003942	RNB domain; Region: RNB; pfam00773
511145003943	S1 RNA binding domain; Region: S1; pfam00575
511145003944	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4950
511145003945	Uncharacterized conserved protein [Function unknown]; Region: COG2128
511145003946	Carboxymuconolactone decarboxylase family; Region: CMD; cl00460
511145003947	Enoyl-[acyl-carrier-protein]; Region: FabI; COG0623
511145003948	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
511145003949	NAD binding site [chemical binding]; other site
511145003950	homotetramer interface [polypeptide binding]; other site
511145003951	homodimer interface [polypeptide binding]; other site
511145003952	substrate binding site [chemical binding]; other site
511145003953	active site
511145003954	Domain of unknown function, appears to be related to a diverse group of endonucleases; Region: Endonuclease_DUF559; cd01038
511145003955	putative active site [active]
511145003956	antimicrobial peptide ABC system ATP-binding protein SapF; Provisional; Region: PRK15112
511145003957	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145003958	Walker A/P-loop; other site
511145003959	ATP binding site [chemical binding]; other site
511145003960	Q-loop/lid; other site
511145003961	ABC transporter signature motif; other site
511145003962	Walker B; other site
511145003963	D-loop; other site
511145003964	H-loop/switch region; other site
511145003965	antimicrobial peptide ABC transporter ATP-binding protein; Provisional; Region: PRK15093
511145003966	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145003967	Walker A/P-loop; other site
511145003968	ATP binding site [chemical binding]; other site
511145003969	Q-loop/lid; other site
511145003970	ABC transporter signature motif; other site
511145003971	Walker B; other site
511145003972	D-loop; other site
511145003973	H-loop/switch region; other site
511145003974	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145003975	antimicrobial peptide ABC transporter permease SapC; Provisional; Region: PRK15111
511145003976	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
511145003977	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003978	dimer interface [polypeptide binding]; other site
511145003979	conserved gate region; other site
511145003980	putative PBP binding loops; other site
511145003981	ABC-ATPase subunit interface; other site
511145003982	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SapB; COG4168
511145003983	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145003984	dimer interface [polypeptide binding]; other site
511145003985	conserved gate region; other site
511145003986	putative PBP binding loops; other site
511145003987	ABC-ATPase subunit interface; other site
511145003988	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
511145003989	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
511145003990	peptide binding site [polypeptide binding]; other site
511145003991	Protein of unknown function (DUF2543); Region: DUF2543; pfam10820
511145003992	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145003993	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
511145003994	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
511145003995	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
511145003996	gamma-glutamyl-gamma-aminobutyrate hydrolase; Provisional; Region: puuD; PRK11366
511145003997	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
511145003998	catalytic triad [active]
511145003999	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
511145004000	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004001	non-specific DNA binding site [nucleotide binding]; other site
511145004002	salt bridge; other site
511145004003	sequence-specific DNA binding site [nucleotide binding]; other site
511145004004	Cupin domain; Region: Cupin_2; pfam07883
511145004005	Escherichia coli NADP+-dependent gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase PuuC-like; Region: ALDH_GABALDH-PuuC; cd07112
511145004006	NAD(P) binding site [chemical binding]; other site
511145004007	catalytic residues [active]
511145004008	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
511145004009	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
511145004010	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145004011	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145004012	inhibitor-cofactor binding pocket; inhibition site
511145004013	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145004014	catalytic residue [active]
511145004015	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
511145004016	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145004017	Walker A motif; other site
511145004018	ATP binding site [chemical binding]; other site
511145004019	Walker B motif; other site
511145004020	arginine finger; other site
511145004021	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
511145004022	phage shock protein PspA; Provisional; Region: PRK10698
511145004023	Phage shock protein A (IM30), suppresses sigma54-dependent transcription [Transcription / Signal transduction mechanisms]; Region: PspA; COG1842
511145004024	phage shock protein B; Provisional; Region: pspB; PRK09458
511145004025	DNA-binding transcriptional activator PspC; Provisional; Region: PRK10697
511145004026	phage shock protein C; Region: phageshock_pspC; TIGR02978
511145004027	peripheral inner membrane phage-shock protein; Provisional; Region: PRK10497
511145004028	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
511145004029	active site residue [active]
511145004030	Alpha amylase catalytic domain found in sucrose phosphorylase-like proteins (also called sucrose glucosyltransferase, disaccharide glucosyltransferase, and sucrose-phosphate alpha-D glucosyltransferase); Region: AmyAc_Sucrose_phosphorylase-like_1; cd11356
511145004031	sucrose phosphorylase; Provisional; Region: PRK13840
511145004032	active site
511145004033	homodimer interface [polypeptide binding]; other site
511145004034	catalytic site [active]
511145004035	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
511145004036	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
511145004037	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
511145004038	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004039	dimer interface [polypeptide binding]; other site
511145004040	conserved gate region; other site
511145004041	putative PBP binding loops; other site
511145004042	ABC-ATPase subunit interface; other site
511145004043	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
511145004044	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004045	dimer interface [polypeptide binding]; other site
511145004046	conserved gate region; other site
511145004047	putative PBP binding loops; other site
511145004048	ABC-ATPase subunit interface; other site
511145004049	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145004050	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide and other MDR family members; Region: 2-desacetyl-2-hydroxyethyl_bacteriochlorophyllide_; cd08255
511145004051	putative NAD(P) binding site [chemical binding]; other site
511145004052	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
511145004053	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
511145004054	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
511145004055	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145004056	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145004057	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
511145004058	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
511145004059	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
511145004060	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
511145004061	beta-phosphoglucomutase; Region: bPGM; TIGR01990
511145004062	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145004063	motif II; other site
511145004064	Outer membrane protein G (OmpG); Region: Porin_OmpG; pfam09381
511145004065	Transcriptional regulators [Transcription]; Region: PurR; COG1609
511145004066	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145004067	DNA binding site [nucleotide binding]
511145004068	domain linker motif; other site
511145004069	Ligand-binding domain of uncharacterized transcription regulator ycjW which is a member of the LacI-GalR family repressors; Region: PBP1_ycjW_transcription_regulator_like; cd06294
511145004070	putative dimerization interface [polypeptide binding]; other site
511145004071	putative ligand binding site [chemical binding]; other site
511145004072	Predicted ATPase [General function prediction only]; Region: COG3106
511145004073	hypothetical protein; Provisional; Region: PRK05415
511145004074	Predicted membrane protein [Function unknown]; Region: COG3768
511145004075	DNA-binding transcriptional regulator TyrR; Provisional; Region: PRK10820
511145004076	N-terminal ACT domain of the TyrR protein; Region: ACT_TyrR; cd04877
511145004077	putative aromatic amino acid binding site; other site
511145004078	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145004079	putative active site [active]
511145004080	heme pocket [chemical binding]; other site
511145004081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145004082	Walker A motif; other site
511145004083	ATP binding site [chemical binding]; other site
511145004084	Walker B motif; other site
511145004085	arginine finger; other site
511145004086	Peroxiredoxin (PRX) family, Atypical 2-cys PRX subfamily; composed of PRXs containing peroxidatic and resolving cysteines, similar to the homodimeric thiol specific antioxidant (TSA) protein also known as TRX-dependent thiol peroxidase (Tpx). Tpx is a...; Region: PRX_Atyp2cys; cd03014
511145004087	dimer interface [polypeptide binding]; other site
511145004088	catalytic triad [active]
511145004089	peroxidatic and resolving cysteines [active]
511145004090	L-Ala-D/L-Glu epimerase; Provisional; Region: PRK15129
511145004091	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
511145004092	active site
511145004093	Predicted carboxypeptidase [Amino acid transport and metabolism]; Region: COG2866
511145004094	Peptidase M14-like domain of Escherichia coli Murein Peptide Amidase A and related proteins; Region: M14_MpaA_like; cd06904
511145004095	putative active site [active]
511145004096	Zn binding site [ion binding]; other site
511145004097	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
511145004098	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
511145004099	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145004100	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145004101	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_5; cd08474
511145004102	putative effector binding pocket; other site
511145004103	putative dimerization interface [polypeptide binding]; other site
511145004104	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
511145004105	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
511145004106	peptide binding site [polypeptide binding]; other site
511145004107	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
511145004108	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145004109	Transposase domain (DUF772); Region: DUF772; pfam05598
511145004110	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145004111	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145004112	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145004113	Protein of unknown function (DUF2534); Region: DUF2534; pfam10749
511145004114	universal stress protein UspE; Provisional; Region: PRK11175
511145004115	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145004116	Ligand Binding Site [chemical binding]; other site
511145004117	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145004118	Ligand Binding Site [chemical binding]; other site
511145004119	fumarate/nitrate reduction transcriptional regulator; Provisional; Region: PRK11161
511145004120	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
511145004121	ligand binding site [chemical binding]; other site
511145004122	flexible hinge region; other site
511145004123	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
511145004124	putative switch regulator; other site
511145004125	non-specific DNA interactions [nucleotide binding]; other site
511145004126	DNA binding site [nucleotide binding]
511145004127	sequence specific DNA binding site [nucleotide binding]; other site
511145004128	putative cAMP binding site [chemical binding]; other site
511145004129	O-6-alkylguanine-DNA:cysteine-protein methyltransferase; Provisional; Region: PRK10286
511145004130	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
511145004131	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
511145004132	DNA binding site [nucleotide binding]
511145004133	active site
511145004134	putative aminobenzoyl-glutamate transporter; Provisional; Region: abgT; PRK11339
511145004135	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
511145004136	amidohydrolase; Region: amidohydrolases; TIGR01891
511145004137	putative metal binding site [ion binding]; other site
511145004138	M20 Peptidases Aminoacyclase-1 indole-3-acetic-L-aspartic acid hydrolase from bacteria and archaea; Region: M20_Acy1_IAAspH_bact; cd05665
511145004139	amidohydrolase; Region: amidohydrolases; TIGR01891
511145004140	putative metal binding site [ion binding]; other site
511145004141	dimer interface [polypeptide binding]; other site
511145004142	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09791
511145004143	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145004144	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
511145004145	putative substrate binding pocket [chemical binding]; other site
511145004146	putative dimerization interface [polypeptide binding]; other site
511145004147	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
511145004148	Smr domain; Region: Smr; pfam01713
511145004149	PAS domain S-box; Region: sensory_box; TIGR00229
511145004150	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145004151	putative active site [active]
511145004152	heme pocket [chemical binding]; other site
511145004153	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145004154	metal binding site [ion binding]; metal-binding site
511145004155	active site
511145004156	I-site; other site
511145004157	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
511145004158	Salmonella typhimurium Zn2+ transporter ZntB-like subgroup; Region: ZntB-like_1; cd12833
511145004159	Cl binding site [ion binding]; other site
511145004160	oligomer interface [polypeptide binding]; other site
511145004161	ATP-dependent RNA helicase DbpA; Provisional; Region: PRK11776
511145004162	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
511145004163	ATP binding site [chemical binding]; other site
511145004164	Mg++ binding site [ion binding]; other site
511145004165	motif III; other site
511145004166	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145004167	nucleotide binding region [chemical binding]; other site
511145004168	ATP-binding site [chemical binding]; other site
511145004169	RNA recognition motif in Escherichia coli RNA helicase dbpA and similar proteins; Region: RRM_EcDbpA_like; cd12501
511145004170	putative RNA binding site [nucleotide binding]; other site
511145004171	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
511145004172	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
511145004173	Ligand Binding Site [chemical binding]; other site
511145004174	cryptic prophage Rac
511145004175	Domain of unknown function (DUF3596); Region: DUF3596; pfam12167
511145004176	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
511145004177	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_3; pfam14659
511145004178	phiCTX phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various phage and bacterial integrases, including those similar to phage integrases: Bordetella and...; Region: INT_phiCTX_C; cd01191
511145004179	Int/Topo IB signature motif; other site
511145004180	Putative excisionase (DUF1233); Region: DUF1233; pfam06806
511145004181	Protein of unknown function (DUF1187); Region: DUF1187; pfam06688
511145004182	restriction alleviation and modification protein; Reviewed; Region: lar; PRK09710
511145004183	recombination and repair protein RecT; Reviewed; Region: recT; PRK09846
511145004184	exonuclease VIII; Reviewed; Region: PRK09709
511145004185	Enterobacterial exodeoxyribonuclease VIII; Region: Exonuc_VIII; pfam06630
511145004186	PDDEXK-like domain of unknown function (DUF3799); Region: DUF3799; pfam12684
511145004187	hypothetical protein; Reviewed; Region: PRK09790
511145004188	FtsZ inhibitor protein; Reviewed; Region: kil; PRK11354
511145004189	Superinfection exclusion protein B; Region: SieB; pfam14163
511145004190	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
511145004191	UBA-like domain; Region: UBA_4; pfam14555
511145004192	Uncharacterized protein conserved in bacteria, prophage-related [Function unknown]; Region: COG4197
511145004193	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004194	sequence-specific DNA binding site [nucleotide binding]; other site
511145004195	salt bridge; other site
511145004196	Protein of unknown function (DUF1019); Region: DUF1019; pfam06254
511145004197	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3756
511145004198	primosomal protein DnaI; Provisional; Region: PRK02854
511145004199	putative replication protein; Provisional; Region: PRK12377
511145004200	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145004201	Walker A motif; other site
511145004202	ATP binding site [chemical binding]; other site
511145004203	Walker B motif; other site
511145004204	arginine finger; other site
511145004205	Lipoprotein Rz1 precursor; Region: Rz1; pfam06085
511145004206	Cation transport protein; Region: TrkH; cl17365
511145004207	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
511145004208	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
511145004209	ParB-like nuclease domain; Region: ParBc; pfam02195
511145004210	Prophage tail fibre N-terminal; Region: phage_tail_N; pfam08400
511145004211	Phage tail fibre repeat; Region: Phage_fiber_2; pfam03406
511145004212	Phage Tail Collar Domain; Region: Collar; pfam07484
511145004213	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
511145004214	multiple promoter invertase; Provisional; Region: mpi; PRK13413
511145004215	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
511145004216	catalytic residues [active]
511145004217	catalytic nucleophile [active]
511145004218	Presynaptic Site I dimer interface [polypeptide binding]; other site
511145004219	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
511145004220	Synaptic Flat tetramer interface [polypeptide binding]; other site
511145004221	Synaptic Site I dimer interface [polypeptide binding]; other site
511145004222	DNA binding site [nucleotide binding]
511145004223	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
511145004224	DNA-binding interface [nucleotide binding]; DNA binding site
511145004225	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145004226	Ligand Binding Site [chemical binding]; other site
511145004227	Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers...; Region: gram_neg_porins; cd00342
511145004228	trimer interface [polypeptide binding]; other site
511145004229	eyelet of channel; other site
511145004230	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
511145004231	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
511145004232	dimer interface [polypeptide binding]; other site
511145004233	PYR/PP interface [polypeptide binding]; other site
511145004234	TPP binding site [chemical binding]; other site
511145004235	substrate binding site [chemical binding]; other site
511145004236	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
511145004237	Domain of unknown function; Region: EKR; pfam10371
511145004238	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
511145004239	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
511145004240	TPP-binding site [chemical binding]; other site
511145004241	dimer interface [polypeptide binding]; other site
511145004242	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
511145004243	heat-inducible protein; Provisional; Region: PRK10449
511145004244	D-Lactate and related Dehydrogenases, NAD-binding and catalytic domains; Region: LDH_like_2; cd12183
511145004245	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
511145004246	putative ligand binding site [chemical binding]; other site
511145004247	putative NAD binding site [chemical binding]; other site
511145004248	catalytic site [active]
511145004249	hypothetical protein; Provisional; Region: PRK10695
511145004250	YnbE-like lipoprotein; Region: Lipoprotein_19; pfam13617
511145004251	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3784
511145004252	DNA-binding transcriptional activator FeaR; Provisional; Region: PRK09685
511145004253	AraC-binding-like domain; Region: AraC_binding_2; pfam14525
511145004254	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145004255	Escherichia coli NAD+-dependent phenylacetaldehyde dehydrogenase PadA-like; Region: ALDH_PADH_NahF; cd07113
511145004256	NAD(P) binding site [chemical binding]; other site
511145004257	catalytic residues [active]
511145004258	tyramine oxidase; Provisional; Region: tynA; PRK14696
511145004259	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
511145004260	Copper amine oxidase, N2 domain; Region: Cu_amine_oxidN2; pfam02727
511145004261	Copper amine oxidase, N3 domain; Region: Cu_amine_oxidN3; pfam02728
511145004262	Copper amine oxidase, enzyme domain; Region: Cu_amine_oxid; pfam01179
511145004263	bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; Provisional; Region: PRK11563
511145004264	N-terminal domain of the monoamine oxidase C dehydratase; Region: ALDH_MaoC-N; cd07128
511145004265	substrate binding site [chemical binding]; other site
511145004266	dimer interface [polypeptide binding]; other site
511145004267	NADP binding site [chemical binding]; other site
511145004268	catalytic residues [active]
511145004269	MaoC_C  The C-terminal hot dog fold of the MaoC (monoamine oxidase C) dehydratase regulatory protein. Orthologs of MaoC include PaaZ [Escherichia coli] and PaaN [Pseudomonas putida], which are putative ring-opening enzymes involved in phenylacetic acid...; Region: MaoC_C; cd03452
511145004270	substrate binding site [chemical binding]; other site
511145004271	phenylacetate-CoA oxygenase subunit PaaA; Provisional; Region: paaA; PRK13778
511145004272	phenylacetate-CoA oxygenase subunit PaaB; Provisional; Region: paaB; PRK13781
511145004273	phenylacetate-CoA oxygenase, PaaI subunit; Region: PA_CoA_Oxy3; TIGR02158
511145004274	Predicted metal-sulfur cluster biosynthetic enzyme [General function prediction only]; Region: PaaD; COG2151
511145004275	phenylacetate-CoA oxygenase, PaaJ subunit; Region: PA_CoA_Oxy4; TIGR02159
511145004276	Transposase zinc-ribbon domain; Region: Zn_Tnp_IS1595; pfam12760
511145004277	phenylacetate-CoA oxygenase/reductase, PaaK subunit; Region: PA_CoA_Oxy5; TIGR02160
511145004278	NAD(P) binding domain of ferredoxin reductase like phenylacetic acid (PA) degradation oxidoreductase. PA oxidoreductases of E. coli hydroxylate PA-CoA in the second step of PA degradation. Members of this group typically fuse a ferredoxin reductase-like...; Region: PA_degradation_oxidoreductase_like; cd06214
511145004279	FAD binding pocket [chemical binding]; other site
511145004280	FAD binding motif [chemical binding]; other site
511145004281	phosphate binding motif [ion binding]; other site
511145004282	beta-alpha-beta structure motif; other site
511145004283	NAD(p) ribose binding residues [chemical binding]; other site
511145004284	NAD binding pocket [chemical binding]; other site
511145004285	NAD(P)-pyrophosphate-nicotinamide binding residues [chemical binding]; other site
511145004286	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145004287	catalytic loop [active]
511145004288	iron binding site [ion binding]; other site
511145004289	enoyl-CoA hydratase-isomerase; Provisional; Region: PRK09674
511145004290	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145004291	substrate binding site [chemical binding]; other site
511145004292	oxyanion hole (OAH) forming residues; other site
511145004293	trimer interface [polypeptide binding]; other site
511145004294	enoyl-CoA hydratase; Provisional; Region: PRK08140
511145004295	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145004296	substrate binding site [chemical binding]; other site
511145004297	oxyanion hole (OAH) forming residues; other site
511145004298	trimer interface [polypeptide binding]; other site
511145004299	3-hydroxyacyl-CoA dehydrogenase PaaC; Region: PaaC-3OHAcCoADH; TIGR02279
511145004300	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
511145004301	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145004302	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145004303	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
511145004304	CoenzymeA binding site [chemical binding]; other site
511145004305	subunit interaction site [polypeptide binding]; other site
511145004306	PHB binding site; other site
511145004307	beta-ketoadipyl CoA thiolase; Validated; Region: PRK09050
511145004308	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
511145004309	dimer interface [polypeptide binding]; other site
511145004310	active site
511145004311	Phenylacetate-CoA ligase (also known as PaaK); Region: PaaK; cd05913
511145004312	phenylacetate-CoA ligase; Region: PA_CoA_ligase; TIGR02155
511145004313	active site
511145004314	AMP binding site [chemical binding]; other site
511145004315	homodimer interface [polypeptide binding]; other site
511145004316	acyl-activating enzyme (AAE) consensus motif; other site
511145004317	CoA binding site [chemical binding]; other site
511145004318	PaaX-like protein; Region: PaaX; pfam07848
511145004319	phenylacetic acid degradation operon negative regulatory protein PaaX; Region: PaaX_trns_reg; TIGR02277
511145004320	PaaX-like protein C-terminal domain; Region: PaaX_C; pfam08223
511145004321	phenylacetic acid degradation protein PaaY; Region: PaaY; TIGR02287
511145004322	paaY-like: This group is composed by uncharacterized proteins with similarity to the protein product of the E. coli paaY gene, which is part of the paa gene cluster responsible for phenylacetic acid degradation. Proteins in this group are expected to...; Region: LbH_paaY_like; cd04745
511145004323	putative trimer interface [polypeptide binding]; other site
511145004324	putative metal binding site [ion binding]; other site
511145004325	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145004326	HTH-like domain; Region: HTH_21; pfam13276
511145004327	Integrase core domain; Region: rve; pfam00665
511145004328	Integrase core domain; Region: rve_3; pfam13683
511145004329	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145004330	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145004331	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
511145004332	Helix-turn-helix domain; Region: HTH_38; pfam13936
511145004333	Homeodomain-like domain; Region: HTH_32; pfam13565
511145004334	Integrase core domain; Region: rve; pfam00665
511145004335	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145004336	active site
511145004337	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145004338	catalytic tetrad [active]
511145004339	Protein of unknown function (DUF342); Region: DUF342; cl19219
511145004340	Protein of unknown function (DUF2773); Region: DUF2773; pfam10971
511145004341	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
511145004342	Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase [General function prediction only]; Region: COG4589
511145004343	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
511145004344	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
511145004345	Putative methyltransferase; Region: Methyltransf_20; pfam12147
511145004346	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145004347	S-adenosylmethionine binding site [chemical binding]; other site
511145004348	PAP2_like proteins, Aur1_like subfamily. Yeast Aur1p or Ipc1p is necessary for the addition of inositol phosphate to ceramide, an essential step in yeast sphingolipid synthesis, and is the target of several antifungal compounds such as aureobasidin; Region: PAP2_Aur1_like; cd03386
511145004349	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
511145004350	active site
511145004351	Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or...; Region: DSPc; cd00127
511145004352	Predicted protein-tyrosine phosphatase [Signal transduction mechanisms]; Region: CDC14; COG2453
511145004353	active site
511145004354	catalytic residues [active]
511145004355	azoreductase; Reviewed; Region: PRK00170
511145004356	ATP-dependent RNA helicase HrpA; Provisional; Region: PRK11131
511145004357	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145004358	ATP binding site [chemical binding]; other site
511145004359	putative Mg++ binding site [ion binding]; other site
511145004360	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145004361	nucleotide binding region [chemical binding]; other site
511145004362	ATP-binding site [chemical binding]; other site
511145004363	Helicase associated domain (HA2); Region: HA2; pfam04408
511145004364	Oligonucleotide/oligosaccharide-binding (OB)-fold; Region: OB_NTP_bind; pfam07717
511145004365	Domain of unknown function (DUF3418); Region: DUF3418; pfam11898
511145004366	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
511145004367	putative active site [active]
511145004368	Escherichia coli lactaldehyde dehydrogenase AldA-like; Region: ALDH_LactADH-AldA; cd07088
511145004369	NAD binding site [chemical binding]; other site
511145004370	catalytic residues [active]
511145004371	substrate binding site [chemical binding]; other site
511145004372	cytochrome b561; Provisional; Region: PRK11513
511145004373	hypothetical protein; Provisional; Region: PRK10040
511145004374	small toxic polypeptide; Provisional; Region: PRK09738
511145004375	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
511145004376	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
511145004377	dimer interface [polypeptide binding]; other site
511145004378	ligand binding site [chemical binding]; other site
511145004379	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145004380	dimerization interface [polypeptide binding]; other site
511145004381	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
511145004382	dimer interface [polypeptide binding]; other site
511145004383	putative CheW interface [polypeptide binding]; other site
511145004384	pca operon transcription factor PcaQ; Region: TF_pcaQ; TIGR02424
511145004385	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145004386	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145004387	dimerization interface [polypeptide binding]; other site
511145004388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5383
511145004389	Periplasmic glucans biosynthesis protein [Inorganic ion transport and metabolism]; Region: MdoG; COG3131
511145004390	hypothetical protein; Provisional; Region: PRK11415
511145004391	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
511145004392	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145004393	Coenzyme A binding pocket [chemical binding]; other site
511145004394	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
511145004395	putative trimer interface [polypeptide binding]; other site
511145004396	putative CoA binding site [chemical binding]; other site
511145004397	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cd00208
511145004398	putative trimer interface [polypeptide binding]; other site
511145004399	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
511145004400	putative CoA binding site [chemical binding]; other site
511145004401	putative trimer interface [polypeptide binding]; other site
511145004402	putative CoA binding site [chemical binding]; other site
511145004403	Tellurite-resistance/Dicarboxylate Transporter (TDT) family includes TehA protein; Region: TDT_TehA; cd09324
511145004404	gating phenylalanine in ion channel; other site
511145004405	tellurite resistance protein TehB; Provisional; Region: PRK11207
511145004406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145004407	S-adenosylmethionine binding site [chemical binding]; other site
511145004408	Protein of unknown function (DUF3313); Region: DUF3313; pfam11769
511145004409	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
511145004410	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
511145004411	Probable transposase; Region: OrfB_IS605; pfam01385
511145004412	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
511145004413	Uncharacterized protein involved in benzoate metabolism [Secondary metabolites biosynthesis, transport, and catabolism]; Region: BenE; COG3135
511145004414	benzoate transporter; Region: benE; TIGR00843
511145004415	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
511145004416	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004417	non-specific DNA binding site [nucleotide binding]; other site
511145004418	salt bridge; other site
511145004419	sequence-specific DNA binding site [nucleotide binding]; other site
511145004420	Cupin domain; Region: Cupin_2; pfam07883
511145004421	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
511145004422	Collagenase; Region: DUF3656; pfam12392
511145004423	Protein of unknown function (DUF2554); Region: DUF2554; pfam10829
511145004424	YcfA-like protein; Region: YcfA; pfam07927
511145004425	Predicted nuclease of the RNAse H fold, HicB family [General    function prediction only]; Region: COG1598
511145004426	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004427	sequence-specific DNA binding site [nucleotide binding]; other site
511145004428	salt bridge; other site
511145004429	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
511145004430	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145004431	DNA-binding site [nucleotide binding]; DNA binding site
511145004432	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145004433	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145004434	homodimer interface [polypeptide binding]; other site
511145004435	catalytic residue [active]
511145004436	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
511145004437	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
511145004438	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145004439	Walker A/P-loop; other site
511145004440	ATP binding site [chemical binding]; other site
511145004441	Q-loop/lid; other site
511145004442	ABC transporter signature motif; other site
511145004443	Walker B; other site
511145004444	D-loop; other site
511145004445	H-loop/switch region; other site
511145004446	TOBE domain; Region: TOBE_2; pfam08402
511145004447	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004448	dimer interface [polypeptide binding]; other site
511145004449	conserved gate region; other site
511145004450	putative PBP binding loops; other site
511145004451	ABC-ATPase subunit interface; other site
511145004452	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
511145004453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004454	dimer interface [polypeptide binding]; other site
511145004455	conserved gate region; other site
511145004456	putative PBP binding loops; other site
511145004457	ABC-ATPase subunit interface; other site
511145004458	Escherichia coli NAD+-dependent gamma-aminobutyraldehyde dehydrogenase YdcW-like; Region: ALDH_ABALDH-YdcW; cd07092
511145004459	tetrameric interface [polypeptide binding]; other site
511145004460	NAD binding site [chemical binding]; other site
511145004461	catalytic residues [active]
511145004462	substrate binding site [chemical binding]; other site
511145004463	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
511145004464	Protein of unknown function (DUF2526); Region: DUF2526; pfam10735
511145004465	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3238
511145004466	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
511145004467	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145004468	Coenzyme A binding pocket [chemical binding]; other site
511145004469	Putative NADP-dependent oxidoreductases [General function prediction only]; Region: COG2130
511145004470	Prostaglandin dehydrogenases; Region: PGDH; cd05288
511145004471	NAD(P) binding site [chemical binding]; other site
511145004472	substrate binding site [chemical binding]; other site
511145004473	dimer interface [polypeptide binding]; other site
511145004474	colanic acid/biofilm transcriptional regulator; Provisional; Region: PRK11414
511145004475	DNA-binding site [nucleotide binding]; DNA binding site
511145004476	helix_turn_helix gluconate operon transcriptional repressor; Region: HTH_GNTR; smart00345
511145004477	FCD domain; Region: FCD; pfam07729
511145004478	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
511145004479	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145004480	N-terminal plug; other site
511145004481	ligand-binding site [chemical binding]; other site
511145004482	Uncharacterized conserved protein [Function unknown]; Region: COG3391
511145004483	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
511145004484	L-asparagine permease; Provisional; Region: PRK15049
511145004485	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145004486	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
511145004487	C-terminal domain interface [polypeptide binding]; other site
511145004488	GSH binding site (G-site) [chemical binding]; other site
511145004489	Glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: Gst; COG0625
511145004490	dimer interface [polypeptide binding]; other site
511145004491	C-terminal, alpha helical domain of the Glutathione S-transferase family; Region: GST_C_family; cl02776
511145004492	N-terminal domain interface [polypeptide binding]; other site
511145004493	dimer interface [polypeptide binding]; other site
511145004494	substrate binding pocket (H-site) [chemical binding]; other site
511145004495	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145004496	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145004497	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145004498	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145004499	4-oxalocrotonate tautomerase; Provisional; Region: PRK01271
511145004500	active site 1 [active]
511145004501	dimer interface [polypeptide binding]; other site
511145004502	hexamer interface [polypeptide binding]; other site
511145004503	active site 2 [active]
511145004504	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
511145004505	N-hydroxyarylamine O-acetyltransferase; Provisional; Region: PRK15047
511145004506	hypothetical protein; Provisional; Region: PRK10281
511145004507	phenazine biosynthesis protein PhzF family; Region: PhzF_family; TIGR00654
511145004508	respiratory nitrate reductase, gamma subunit; Region: narI; TIGR00351
511145004509	nitrate reductase 2 subunit delta; Provisional; Region: PRK15054
511145004510	Nitrate reductase beta subunit [Energy production and conversion]; Region: NarY; COG1140
511145004511	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145004512	Respiratory nitrate reductase beta C-terminal; Region: Nitr_red_bet_C; pfam14711
511145004513	Nitrate reductase alpha subunit [Energy production and conversion]; Region: NarG; COG5013
511145004514	Respiratory nitrate reductase alpha N-terminal; Region: Nitr_red_alph_N; pfam14710
511145004515	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_Nitrate-R-NarG-like; cd02750
511145004516	[4Fe-4S] binding site [ion binding]; other site
511145004517	molybdopterin cofactor binding site [chemical binding]; other site
511145004518	Respiratory nitrate reductase A (NarGHI), alpha chain (NarG) and related proteins. Under anaerobic conditions in the presence of nitrate, E. coli synthesizes the cytoplasmic membrane-bound quinol-nitrate oxidoreductase (NarGHI), which reduces nitrate to...; Region: MopB_CT_Nitrate-R-NarG-like; cd02776
511145004519	molybdopterin cofactor binding site; other site
511145004520	nitrate/nitrite transport protein NarU; Provisional; Region: PRK15034
511145004521	Nitrate/nitrite transporter [Inorganic ion transport and metabolism]; Region: NarK; COG2223
511145004522	aromatic amino acid exporter; Provisional; Region: PRK11689
511145004523	EamA-like transporter family; Region: EamA; pfam00892
511145004524	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
511145004525	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
511145004526	[4Fe-4S] binding site [ion binding]; other site
511145004527	molybdopterin cofactor binding site; other site
511145004528	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
511145004529	molybdopterin cofactor binding site; other site
511145004530	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
511145004531	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145004532	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
511145004533	formate dehydrogenase-N subunit gamma; Provisional; Region: PRK10179
511145004534	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004535	non-specific DNA binding site [nucleotide binding]; other site
511145004536	salt bridge; other site
511145004537	sequence-specific DNA binding site [nucleotide binding]; other site
511145004538	ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional; Region: PRK09422
511145004539	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD3; cd08297
511145004540	NAD binding site [chemical binding]; other site
511145004541	substrate binding site [chemical binding]; other site
511145004542	catalytic Zn binding site [ion binding]; other site
511145004543	tetramer interface [polypeptide binding]; other site
511145004544	structural Zn binding site [ion binding]; other site
511145004545	malate dehydrogenase; Provisional; Region: PRK13529
511145004546	Malic enzyme, N-terminal domain; Region: malic; pfam00390
511145004547	NAD(P) binding domain of malic enzyme (ME), subgroup 1; Region: NAD_bind_1_malic_enz; cd05312
511145004548	NAD(P) binding site [chemical binding]; other site
511145004549	30S ribosomal subunit S22; Reviewed; Region: rpsV; PRK10057
511145004550	Putative biofilm-dependent modulation protein; Region: BDM; cl11581
511145004551	peroxiredoxin, OsmC subfamily; Region: osmo_induc_OsmC; TIGR03562
511145004552	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
511145004553	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145004554	Walker A/P-loop; other site
511145004555	ATP binding site [chemical binding]; other site
511145004556	Q-loop/lid; other site
511145004557	ABC transporter signature motif; other site
511145004558	Walker B; other site
511145004559	D-loop; other site
511145004560	H-loop/switch region; other site
511145004561	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
511145004562	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
511145004563	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145004564	Walker A/P-loop; other site
511145004565	ATP binding site [chemical binding]; other site
511145004566	Q-loop/lid; other site
511145004567	ABC transporter signature motif; other site
511145004568	Walker B; other site
511145004569	D-loop; other site
511145004570	H-loop/switch region; other site
511145004571	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
511145004572	D-ala-D-ala transporter subunit; Provisional; Region: PRK09881
511145004573	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
511145004574	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004575	dimer interface [polypeptide binding]; other site
511145004576	conserved gate region; other site
511145004577	putative PBP binding loops; other site
511145004578	ABC-ATPase subunit interface; other site
511145004579	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
511145004580	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145004581	dimer interface [polypeptide binding]; other site
511145004582	conserved gate region; other site
511145004583	putative PBP binding loops; other site
511145004584	ABC-ATPase subunit interface; other site
511145004585	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
511145004586	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_7; cd08512
511145004587	D-alanyl-D-alanine dipeptidase; Provisional; Region: PRK10178
511145004588	cyclic-di-GMP phosphodiesterase; Provisional; Region: PRK11359
511145004589	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145004590	putative active site [active]
511145004591	heme pocket [chemical binding]; other site
511145004592	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145004593	putative active site [active]
511145004594	heme pocket [chemical binding]; other site
511145004595	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145004596	metal binding site [ion binding]; metal-binding site
511145004597	active site
511145004598	I-site; other site
511145004599	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145004600	Globin domain present in Globin-Coupled-Sensors (GCS). These domains detect changes in intracellular concentrations of oxygen, carbon monoxyde, or nitrous oxide,  which result in aerotaxis and/or gene regulation. One subgroup, the HemATs, are aerotactic...; Region: sensor_globin; cd01068
511145004601	heme-binding site [chemical binding]; other site
511145004602	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145004603	metal binding site [ion binding]; metal-binding site
511145004604	active site
511145004605	I-site; other site
511145004606	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1649
511145004607	glutamate:gamma-aminobutyrate antiporter; Region: 2A0307_GadC; TIGR00910
511145004608	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
511145004609	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145004610	catalytic residue [active]
511145004611	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
511145004612	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
511145004613	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
511145004614	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
511145004615	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
511145004616	Porin superfamily.  These outer membrane channels share a beta-barrel structure that differ in strand and shear number.  Classical (gram-negative ) porins are non-specific channels for small hydrophillic molecules and form 16 beta-stranded barrels (16,20)...; Region: OM_channels; cl17244
511145004617	Outer membrane receptor proteins, mostly Fe transport [Inorganic ion transport and metabolism]; Region: CirA; COG1629
511145004618	ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only]; Region: COG4178
511145004619	ABC transporter transmembrane region 2; Region: ABC_membrane_2; cl00549
511145004620	ATP-binding cassette domain of peroxisomal transporter, subfamily D; Region: ABCD_peroxisomal_ALDP; cd03223
511145004621	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
511145004622	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145004623	FeS/SAM binding site; other site
511145004624	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
511145004625	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
511145004626	Sulfatase; Region: Sulfatase; pfam00884
511145004627	transcriptional regulator YdeO; Provisional; Region: PRK09940
511145004628	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145004629	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145004630	putative oxidoreductase; Provisional; Region: PRK09939
511145004631	The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins; Region: MopB_ydeP; cd02767
511145004632	putative molybdopterin cofactor binding site [chemical binding]; other site
511145004633	The MopB_CT_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. This CD is of the conserved molybdopterin_binding C-terminal (MopB_CT) region...; Region: MopB_CT_ydeP; cd02787
511145004634	putative molybdopterin cofactor binding site; other site
511145004635	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
511145004636	mannosyl binding site [chemical binding]; other site
511145004637	Fimbrial protein; Region: Fimbrial; pfam00419
511145004638	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145004639	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145004640	Dif; site of action for XerCD chromosome resolvase; required for proper segregation of circular daughter chromosomes; Dif; recA-independent recombination site in terminus
511145004641	HipA N-terminal domain; Region: couple_hipA; TIGR03071
511145004642	Toxin module HipA, protein kinase of phosphatidylinositol 3/4-kinase superfamily [General function prediction only]; Region: HipA; COG3550
511145004643	HipA-like N-terminal domain; Region: HipA_N; pfam07805
511145004644	HipA-like C-terminal domain; Region: HipA_C; pfam07804
511145004645	beta subunit of N-acylethanolamine-hydrolyzing acid amidase; Region: NAAA-beta; pfam15508
511145004646	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
511145004647	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004648	non-specific DNA binding site [nucleotide binding]; other site
511145004649	salt bridge; other site
511145004650	sequence-specific DNA binding site [nucleotide binding]; other site
511145004651	autoinducer-2 (AI-2) kinase; Provisional; Region: PRK10939
511145004652	Autoinducer-2 kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_AI-2K; cd07775
511145004653	putative N- and C-terminal domain interface [polypeptide binding]; other site
511145004654	putative active site [active]
511145004655	putative MgATP binding site [chemical binding]; other site
511145004656	catalytic site [active]
511145004657	metal binding site [ion binding]; metal-binding site
511145004658	putative carbohydrate binding site [chemical binding]; other site
511145004659	transcriptional regulator LsrR; Provisional; Region: PRK15418
511145004660	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
511145004661	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
511145004662	autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional; Region: PRK15439
511145004663	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145004664	Walker A/P-loop; other site
511145004665	ATP binding site [chemical binding]; other site
511145004666	Q-loop/lid; other site
511145004667	ABC transporter signature motif; other site
511145004668	Walker B; other site
511145004669	D-loop; other site
511145004670	H-loop/switch region; other site
511145004671	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145004672	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145004673	TM-ABC transporter signature motif; other site
511145004674	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145004675	TM-ABC transporter signature motif; other site
511145004676	Periplasmic binding domain of autoinducer-2 (AI-2) receptor LsrB from Salmonella typhimurium and its close homologs; Region: PBP1_LsrB_Quorum_Sensing; cd06302
511145004677	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
511145004678	ligand binding site [chemical binding]; other site
511145004679	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
511145004680	putative active site; other site
511145004681	catalytic residue [active]
511145004682	autoinducer-2 (AI-2) modifying protein LsrG; Provisional; Region: PRK10486
511145004683	Trans-aconitate methyltransferase [General function prediction only]; Region: Tam; COG4106
511145004684	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145004685	S-adenosylmethionine binding site [chemical binding]; other site
511145004686	Predicted membrane protein [Function unknown]; Region: COG3781
511145004687	altronate oxidoreductase; Provisional; Region: PRK03643
511145004688	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
511145004689	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
511145004690	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145004691	metal binding site [ion binding]; metal-binding site
511145004692	active site
511145004693	I-site; other site
511145004694	Domain of unknown function (DUF4186); Region: DUF4186; pfam13811
511145004695	glutaminase; Provisional; Region: PRK00971
511145004696	Mycobacterium tuberculosis succinate-semialdehyde dehydrogenase 1-like; Region: ALDH_SSADH1_GabD1; cd07100
511145004697	NAD(P) binding site [chemical binding]; other site
511145004698	catalytic residues [active]
511145004699	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145004700	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145004701	The C-terminal substrate binding domain of LysR-type transcriptional regulators, YofA and SoxR, contains the type 2 periplasmic binding fold; Region: PBP2_YofA_SoxR_like; cd08442
511145004702	putative dimerization interface [polypeptide binding]; other site
511145004703	putative arabinose transporter; Provisional; Region: PRK03545
511145004704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145004705	putative substrate translocation pore; other site
511145004706	inner membrane protein; Provisional; Region: PRK10995
511145004707	DNA-binding transcriptional repressor MarR; Provisional; Region: PRK11512
511145004708	Transcriptional regulators [Transcription]; Region: MarR; COG1846
511145004709	DNA-binding transcriptional activator MarA; Provisional; Region: PRK11511
511145004710	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145004711	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145004712	MarB protein; Region: MarB; pfam13999
511145004713	O-acetylserine/cysteine export protein; Provisional; Region: PRK11453
511145004714	EamA-like transporter family; Region: EamA; pfam00892
511145004715	EamA-like transporter family; Region: EamA; pfam00892
511145004716	putative transporter; Provisional; Region: PRK10054
511145004717	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145004718	putative substrate translocation pore; other site
511145004719	diguanylate cyclase; Provisional; Region: PRK09894
511145004720	Chemoreceptor zinc-binding domain; Region: CZB; pfam13682
511145004721	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145004722	metal binding site [ion binding]; metal-binding site
511145004723	active site
511145004724	I-site; other site
511145004725	hypothetical protein; Provisional; Region: PRK10053
511145004726	hypothetical protein; Validated; Region: PRK03657
511145004727	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
511145004728	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
511145004729	active site
511145004730	Zn binding site [ion binding]; other site
511145004731	malonic semialdehyde reductase; Provisional; Region: PRK10538
511145004732	classical (c) SDR, subgroup 5; Region: SDR_c5; cd05346
511145004733	putative NAD(P) binding site [chemical binding]; other site
511145004734	homodimer interface [polypeptide binding]; other site
511145004735	homotetramer interface [polypeptide binding]; other site
511145004736	active site
511145004737	Transcriptional regulators [Transcription]; Region: GntR; COG1802
511145004738	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145004739	DNA-binding site [nucleotide binding]; DNA binding site
511145004740	FCD domain; Region: FCD; pfam07729
511145004741	putative selenium-binding protein YdfZ; Region: YdfZ_fam; TIGR03318
511145004742	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
511145004743	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
511145004744	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
511145004745	cryptic prophage Qin/Kim
511145004746	multiple promoter invertase; Provisional; Region: mpi; PRK13413
511145004747	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
511145004748	catalytic residues [active]
511145004749	catalytic nucleophile [active]
511145004750	Presynaptic Site I dimer interface [polypeptide binding]; other site
511145004751	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
511145004752	Synaptic Flat tetramer interface [polypeptide binding]; other site
511145004753	Synaptic Site I dimer interface [polypeptide binding]; other site
511145004754	DNA binding site [nucleotide binding]
511145004755	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cd00569
511145004756	DNA-binding interface [nucleotide binding]; DNA binding site
511145004757	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
511145004758	Phage Tail Collar Domain; Region: Collar; pfam07484
511145004759	Domain of unknown function (DUF3950); Region: DUF3950; pfam13132
511145004760	Protein of unknown function (DUF1398); Region: DUF1398; pfam07166
511145004761	GnsA/GnsB family; Region: GnsAB; pfam08178
511145004762	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145004763	DNA-binding site [nucleotide binding]; DNA binding site
511145004764	RNA-binding motif; other site
511145004765	Protein of unknown function (DUF2514); Region: DUF2514; pfam10721
511145004766	Endolysins and autolysins are found in viruses and bacteria, respectively. The ds DNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell...; Region: endolysin_autolysin; cd00737
511145004767	catalytic residues [active]
511145004768	Protein of unknown function (DUF1327); Region: DUF1327; pfam07041
511145004769	Lysis protein S; Region: Lysis_S; pfam04971
511145004770	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145004771	DNA-binding site [nucleotide binding]; DNA binding site
511145004772	RNA-binding motif; other site
511145004773	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145004774	DNA-binding site [nucleotide binding]; DNA binding site
511145004775	RNA-binding motif; other site
511145004776	Antitermination protein; Region: Antiterm; pfam03589
511145004777	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048
511145004778	Antitermination protein; Region: Antiterm; pfam03589
511145004779	Protein of unknown function (DUF968); Region: DUF968; pfam06147
511145004780	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
511145004781	active site
511145004782	Hok/gef family; Region: HOK_GEF; pfam01848
511145004783	Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning]; Region: RelE; COG2026
511145004784	bifunctional antitoxin/transcriptional repressor RelB; Provisional; Region: PRK11235
511145004785	FlxA-like protein; Region: FlxA; pfam14282
511145004786	DNA-binding transcriptional regulator DicC; Provisional; Region: PRK09744
511145004787	transcriptional repressor DicA; Reviewed; Region: PRK09706
511145004788	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145004789	non-specific DNA binding site [nucleotide binding]; other site
511145004790	salt bridge; other site
511145004791	sequence-specific DNA binding site [nucleotide binding]; other site
511145004792	Protein of unknown function (DUF1391); Region: DUF1391; pfam07151
511145004793	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
511145004794	DicB protein; Region: DicB; pfam05358
511145004795	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
511145004796	putative oxidoreductase; Provisional; Region: PRK10083
511145004797	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
511145004798	putative NAD(P) binding site [chemical binding]; other site
511145004799	catalytic Zn binding site [ion binding]; other site
511145004800	structural Zn binding site [ion binding]; other site
511145004801	bifunctional D-altronate/D-mannonate dehydratase; Provisional; Region: PRK15072
511145004802	The starvation sensing protein RpsA from E.coli and its homologs are lactonizing enzymes whose putative targets are homoserine lactone (HSL)-derivative. They are part of the mandelate racemase (MR)-like subfamily of the enolase superfamily. Enzymes of...; Region: rpsA; cd03322
511145004803	putative active site pocket [active]
511145004804	putative metal binding site [ion binding]; other site
511145004805	hypothetical protein; Provisional; Region: PRK02237
511145004806	hypothetical protein; Provisional; Region: PRK13659
511145004807	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
511145004808	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145004809	Coenzyme A binding pocket [chemical binding]; other site
511145004810	Uncharacterized protein family (UPF0257); Region: UPF0257; pfam06788
511145004811	Protein of unknown function (DUF1161); Region: DUF1161; pfam06649
511145004812	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
511145004813	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
511145004814	putative [Fe4-S4] binding site [ion binding]; other site
511145004815	putative molybdopterin cofactor binding site [chemical binding]; other site
511145004816	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
511145004817	putative molybdopterin cofactor binding site; other site
511145004818	anaerobic dimethyl sulfoxide reductase, A subunit, DmsA/YnfE family; Region: dmsA_ynfE; TIGR02166
511145004819	This CD (MopB_DmsA-EC) includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_DmsA-EC; cd02770
511145004820	putative [Fe4-S4] binding site [ion binding]; other site
511145004821	putative molybdopterin cofactor binding site [chemical binding]; other site
511145004822	The MopB_CT_DmsA-EC CD includes the DmsA enzyme of the dmsABC operon encoding the anaerobic dimethylsulfoxide reductase (DMSOR) of Escherichia coli and other related DMSOR-like enzymes. Unlike other DMSOR-like enzymes, this group has a  predicted...; Region: MopB_CT_DmsA-EC; cd02794
511145004823	putative molybdopterin cofactor binding site; other site
511145004824	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
511145004825	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145004826	DMSO reductase anchor subunit (DmsC); Region: DmsC; pfam04976
511145004827	twin-argninine leader-binding protein DmsD; Provisional; Region: PRK11621
511145004828	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
511145004829	Cl- selectivity filter; other site
511145004830	Cl- binding residues [ion binding]; other site
511145004831	pore gating glutamate residue; other site
511145004832	dimer interface [polypeptide binding]; other site
511145004833	putative dithiobiotin synthetase; Provisional; Region: PRK12374
511145004834	AAA domain; Region: AAA_26; pfam13500
511145004835	Iron dependent repressor, N-terminal DNA binding domain; Region: Fe_dep_repress; pfam01325
511145004836	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145004837	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145004838	nucleotide binding site [chemical binding]; other site
511145004839	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
511145004840	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
511145004841	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145004842	The C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of aromatic compounds and that of other related regulators, contains type 2 periplasmic binding fold; Region: PBP2_LTTR_aromatics_like; cd08414
511145004843	dimerization interface [polypeptide binding]; other site
511145004844	substrate binding pocket [chemical binding]; other site
511145004845	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
511145004846	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145004847	putative substrate translocation pore; other site
511145004848	hypothetical protein; Provisional; Region: PRK14758
511145004849	V8-like Glu-specific endopeptidase [Amino acid transport and metabolism]; Region: COG3591
511145004850	multidrug efflux system protein MdtI; Provisional; Region: PRK10650
511145004851	multidrug efflux system protein MdtJ; Provisional; Region: PRK10452
511145004852	pheromone autoinducer 2 transporter; Reviewed; Region: tqsA; PRK12287
511145004853	pyridine nucleotide transhydrogenase; Provisional; Region: pntB; PRK09444
511145004854	NAD(P) transhydrogenase subunit alpha; Provisional; Region: pntA; PRK09424
511145004855	Rubrum transdehydrogenase NAD-binding and catalytic domains; Region: Rubrum_tdh; cd05304
511145004856	ligand binding site [chemical binding]; other site
511145004857	homodimer interface [polypeptide binding]; other site
511145004858	NAD(P) binding site [chemical binding]; other site
511145004859	trimer interface B [polypeptide binding]; other site
511145004860	trimer interface A [polypeptide binding]; other site
511145004861	Domain of unknown function (DUF3814); Region: DUF3814; pfam12769
511145004862	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145004863	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145004864	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145004865	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
511145004866	Spore germination protein; Region: Spore_permease; cl17796
511145004867	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
511145004868	pteridine reductase (PR), classical (c) SDRs; Region: PR_SDR_c; cd05357
511145004869	NADP binding site [chemical binding]; other site
511145004870	substrate binding pocket [chemical binding]; other site
511145004871	active site
511145004872	GlpM protein; Region: GlpM; pfam06942
511145004873	DNA-binding transcriptional regulator RstA; Provisional; Region: PRK10701
511145004874	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145004875	active site
511145004876	phosphorylation site [posttranslational modification]
511145004877	intermolecular recognition site; other site
511145004878	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145004879	DNA binding site [nucleotide binding]
511145004880	sensor protein RstB; Provisional; Region: PRK10604
511145004881	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145004882	dimerization interface [polypeptide binding]; other site
511145004883	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145004884	dimer interface [polypeptide binding]; other site
511145004885	phosphorylation site [posttranslational modification]
511145004886	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145004887	ATP binding site [chemical binding]; other site
511145004888	Mg2+ binding site [ion binding]; other site
511145004889	G-X-G motif; other site
511145004890	DNA replication terminus site-binding protein; Provisional; Region: PRK02951
511145004891	fumarate hydratase; Reviewed; Region: fumC; PRK00485
511145004892	Class II fumarases; Region: Fumarase_classII; cd01362
511145004893	active site
511145004894	tetramer interface [polypeptide binding]; other site
511145004895	fumarate hydratase; Provisional; Region: PRK15389
511145004896	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
511145004897	Fumarase C-terminus; Region: Fumerase_C; pfam05683
511145004898	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
511145004899	mannose-6-phosphate isomerase; Provisional; Region: PRK15131
511145004900	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG5339
511145004901	putative outer membrane porin protein; Provisional; Region: PRK11379
511145004902	glucuronide transporter; Provisional; Region: PRK09848
511145004903	putative symporter YagG; Provisional; Region: PRK09669; cl15392
511145004904	beta-D-glucuronidase; Provisional; Region: PRK10150
511145004905	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
511145004906	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
511145004907	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
511145004908	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
511145004909	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145004910	7-alpha-hydroxysteroid dehydrogenase; Validated; Region: PRK06113
511145004911	7 alpha-hydroxysteroid dehydrogenase (7 alpha-HSDH), classical (c) SDRs; Region: 7_alpha_HSDH_SDR_c; cd05365
511145004912	NAD binding site [chemical binding]; other site
511145004913	substrate binding site [chemical binding]; other site
511145004914	homotetramer interface [polypeptide binding]; other site
511145004915	homodimer interface [polypeptide binding]; other site
511145004916	active site
511145004917	DNA-binding transcriptional repressor MalI; Provisional; Region: PRK10014
511145004918	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145004919	DNA binding site [nucleotide binding]
511145004920	domain linker motif; other site
511145004921	Ligand-binding domain of MalI, a transcription regulator of the maltose system of Escherichia coli and its close homologs from other bacteria; Region: PBP1_MalI_like; cd06289
511145004922	putative dimerization interface [polypeptide binding]; other site
511145004923	putative ligand binding site [chemical binding]; other site
511145004924	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
511145004925	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
511145004926	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145004927	active site turn [active]
511145004928	phosphorylation site [posttranslational modification]
511145004929	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
511145004930	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145004931	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145004932	homodimer interface [polypeptide binding]; other site
511145004933	catalytic residue [active]
511145004934	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
511145004935	active site
511145004936	purine riboside binding site [chemical binding]; other site
511145004937	putative oxidoreductase; Provisional; Region: PRK11579
511145004938	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145004939	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145004940	oriC-binding nucleoid-associated protein; Provisional; Region: PRK10391
511145004941	Protein of unknown function (DUF2569); Region: DUF2569; pfam10754
511145004942	electron transport complex protein RsxA; Provisional; Region: PRK05151
511145004943	electron transport complex protein RnfB; Provisional; Region: PRK05113
511145004944	Putative Fe-S cluster; Region: FeS; pfam04060
511145004945	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145004946	electron transport complex protein RnfC; Provisional; Region: PRK05035
511145004947	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
511145004948	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
511145004949	SLBB domain; Region: SLBB; pfam10531
511145004950	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
511145004951	electron transport complex protein RnfD; Reviewed; Region: rnfD; PRK00816
511145004952	electron transport complex protein RnfG; Validated; Region: PRK01908
511145004953	electron transport complex RsxE subunit; Provisional; Region: PRK12405
511145004954	endonuclease III; Provisional; Region: PRK10702
511145004955	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
511145004956	minor groove reading motif; other site
511145004957	helix-hairpin-helix signature motif; other site
511145004958	substrate binding pocket [chemical binding]; other site
511145004959	active site
511145004960	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
511145004961	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
511145004962	putative tripeptide transporter permease; Reviewed; Region: tppB; PRK09584
511145004963	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145004964	putative substrate translocation pore; other site
511145004965	glutathionine S-transferase; Provisional; Region: PRK10542
511145004966	GST_N family, Class Beta subfamily; GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens; Region: GST_N_Beta; cd03057
511145004967	C-terminal domain interface [polypeptide binding]; other site
511145004968	GSH binding site (G-site) [chemical binding]; other site
511145004969	dimer interface [polypeptide binding]; other site
511145004970	C-terminal, alpha helical domain of Class Beta Glutathione S-transferases; Region: GST_C_Beta; cd03188
511145004971	N-terminal domain interface [polypeptide binding]; other site
511145004972	dimer interface [polypeptide binding]; other site
511145004973	substrate binding pocket (H-site) [chemical binding]; other site
511145004974	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
511145004975	dimer interface [polypeptide binding]; other site
511145004976	pyridoxal binding site [chemical binding]; other site
511145004977	ATP binding site [chemical binding]; other site
511145004978	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
511145004979	Protein of unknown function (DUF2859); Region: DUF2859; cl12633
511145004980	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
511145004981	active site
511145004982	HIGH motif; other site
511145004983	dimer interface [polypeptide binding]; other site
511145004984	KMSKS motif; other site
511145004985	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145004986	RNA binding surface [nucleotide binding]; other site
511145004987	pyridoxamine 5'-phosphate oxidase; Provisional; Region: PRK05679
511145004988	Pyridoxamine 5'-phosphate oxidase; Region: Pyridox_oxidase; pfam01243
511145004989	Pyridoxine 5'-phosphate oxidase C-terminal dimerization region; Region: PNPOx_C; pfam10590
511145004990	lysozyme inhibitor; Provisional; Region: PRK11372
511145004991	Uncharacterized protein family (UPF0075); Region: UPF0075; pfam03702
511145004992	Outer membrane lipoprotein [Cell envelope biogenesis, outer membrane]; Region: SlyB; COG3133
511145004993	transcriptional regulator SlyA; Provisional; Region: PRK03573
511145004994	Transcriptional regulators [Transcription]; Region: MarR; COG1846
511145004995	Protein of unknown function (DUF1656); Region: DUF1656; pfam07869
511145004996	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
511145004997	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145004998	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145004999	Fusaric acid resistance protein family; Region: FUSC; pfam04632
511145005000	Fusaric acid resistance protein-like; Region: FUSC_2; cl19401
511145005001	Copper/zinc superoxide dismutase (SOD). superoxide dismutases catalyse the conversion of superoxide radicals to molecular oxygen. Three evolutionarily distinct families of SODs are known, of which the copper/zinc-binding family is one. Defects in the...; Region: Cu-Zn_Superoxide_Dismutase; cd00305
511145005002	E-class dimer interface [polypeptide binding]; other site
511145005003	P-class dimer interface [polypeptide binding]; other site
511145005004	active site
511145005005	Cu2+ binding site [ion binding]; other site
511145005006	Zn2+ binding site [ion binding]; other site
511145005007	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145005008	active site
511145005009	catalytic tetrad [active]
511145005010	Predicted Fe-S protein [General function prediction only]; Region: COG3313
511145005011	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
511145005012	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145005013	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN; cd02933
511145005014	FMN binding site [chemical binding]; other site
511145005015	active site
511145005016	substrate binding site [chemical binding]; other site
511145005017	catalytic residue [active]
511145005018	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
511145005019	dimer interface [polypeptide binding]; other site
511145005020	active site
511145005021	metal binding site [ion binding]; metal-binding site
511145005022	glutathione binding site [chemical binding]; other site
511145005023	DNA polymerase III, epsilon subunit and related 3'-5' exonucleases [DNA replication, recombination, and repair]; Region: DnaQ; COG0847
511145005024	DEDDh 3'-5' exonuclease domain of RNase T; Region: RNaseT; cd06134
511145005025	dimer interface [polypeptide binding]; other site
511145005026	catalytic site [active]
511145005027	putative active site [active]
511145005028	putative substrate binding site [chemical binding]; other site
511145005029	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145005030	putative ATP-dependent helicase Lhr; Provisional; Region: PRK09751
511145005031	ATP binding site [chemical binding]; other site
511145005032	putative Mg++ binding site [ion binding]; other site
511145005033	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145005034	nucleotide binding region [chemical binding]; other site
511145005035	ATP-binding site [chemical binding]; other site
511145005036	DEAD/H associated; Region: DEAD_assoc; pfam08494
511145005037	Glutaredoxin (GRX) family, PKC-interacting cousin of TRX (PICOT)-like subfamily; composed of PICOT and GRX-PICOT-like proteins. The non-PICOT members of this family contain only the GRX-like domain, whereas PICOT contains an N-terminal TRX-like domain...; Region: GRX_PICOT_like; cd03028
511145005038	putative GSH binding site [chemical binding]; other site
511145005039	catalytic residues [active]
511145005040	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
511145005041	NlpC/P60 family; Region: NLPC_P60; pfam00877
511145005042	superoxide dismutase; Provisional; Region: PRK10543
511145005043	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
511145005044	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
511145005045	Arabinose efflux permease [Carbohydrate transport and metabolism]; Region: AraJ; COG2814
511145005046	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005047	putative substrate translocation pore; other site
511145005048	hypothetical protein; Provisional; Region: PRK14756
511145005049	DNA-binding transcriptional repressor PurR; Provisional; Region: PRK10703
511145005050	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145005051	DNA binding site [nucleotide binding]
511145005052	domain linker motif; other site
511145005053	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
511145005054	dimerization interface [polypeptide binding]; other site
511145005055	ligand binding site [chemical binding]; other site
511145005056	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
511145005057	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145005058	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145005059	dimerization interface [polypeptide binding]; other site
511145005060	putative transporter; Provisional; Region: PRK11043
511145005061	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005062	putative substrate translocation pore; other site
511145005063	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
511145005064	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
511145005065	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005066	S-adenosylmethionine binding site [chemical binding]; other site
511145005067	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
511145005068	Lumazine binding domain; Region: Lum_binding; pfam00677
511145005069	Lumazine binding domain; Region: Lum_binding; pfam00677
511145005070	multidrug efflux protein; Reviewed; Region: PRK01766
511145005071	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Vibrio cholerae NorM; Region: MATE_NorM_like; cd13131
511145005072	cation binding site [ion binding]; other site
511145005073	hypothetical protein; Provisional; Region: PRK09945
511145005074	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
511145005075	putative monooxygenase; Provisional; Region: PRK11118
511145005076	hypothetical protein; Provisional; Region: PRK09897
511145005077	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4529
511145005078	hypothetical protein; Provisional; Region: PRK09946
511145005079	thiosulfate reductase cytochrome B subunit; Provisional; Region: PRK15006
511145005080	Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion]; Region: COG4117
511145005081	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
511145005082	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145005083	hypothetical protein; Provisional; Region: PRK09947
511145005084	putative oxidoreductase; Provisional; Region: PRK09849
511145005085	Aldehyde ferredoxin oxidoreductase, N-terminal domain; Region: AFOR_N; pfam02730
511145005086	Aldehyde ferredoxin oxidoreductase, domains 2 & 3; Region: AFOR_C; pfam01314
511145005087	hypothetical protein; Provisional; Region: PRK09898
511145005088	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145005089	hypothetical protein; Provisional; Region: PRK10292
511145005090	pyruvate kinase; Provisional; Region: PRK09206
511145005091	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
511145005092	domain interfaces; other site
511145005093	active site
511145005094	murein lipoprotein; Provisional; Region: PRK15396
511145005095	L,D-transpeptidase; Provisional; Region: PRK10260
511145005096	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145005097	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145005098	cysteine desufuration protein SufE; Provisional; Region: PRK09296
511145005099	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
511145005100	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145005101	catalytic residue [active]
511145005102	cysteine desulfurase activator complex subunit SufD; Provisional; Region: PRK10948
511145005103	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
511145005104	cysteine desulfurase ATPase component; Reviewed; Region: sufC; PRK09580
511145005105	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
511145005106	Walker A/P-loop; other site
511145005107	ATP binding site [chemical binding]; other site
511145005108	Q-loop/lid; other site
511145005109	ABC transporter signature motif; other site
511145005110	Walker B; other site
511145005111	D-loop; other site
511145005112	H-loop/switch region; other site
511145005113	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
511145005114	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
511145005115	iron-sulfur cluster assembly scaffold protein; Provisional; Region: sufA; PRK09504
511145005116	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
511145005117	CoenzymeA binding site [chemical binding]; other site
511145005118	subunit interaction site [polypeptide binding]; other site
511145005119	PHB binding site; other site
511145005120	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
511145005121	FAD binding domain; Region: FAD_binding_4; pfam01565
511145005122	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
511145005123	Fe-S oxidoreductase [Energy production and conversion]; Region: GlpC; COG0247
511145005124	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145005125	putative inner membrane protein; Provisional; Region: PRK10983
511145005126	Domain of unknown function (DUF1870); Region: DUF1870; pfam08965
511145005127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005128	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145005129	putative substrate translocation pore; other site
511145005130	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005131	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145005132	putative substrate translocation pore; other site
511145005133	quinate/shikimate dehydrogenase; Reviewed; Region: PRK12749
511145005134	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
511145005135	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
511145005136	shikimate binding site; other site
511145005137	NAD(P) binding site [chemical binding]; other site
511145005138	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
511145005139	active site
511145005140	catalytic residue [active]
511145005141	dimer interface [polypeptide binding]; other site
511145005142	Acyl CoA:acetate/3-ketoacid CoA transferase [Lipid metabolism]; Region: COG4670
511145005143	Coenzyme A transferase; Region: CoA_trans; smart00882
511145005144	Coenzyme A transferase; Region: CoA_trans; cl17247
511145005145	putative acyl-CoA dehydrogenase; Provisional; Region: PRK12341
511145005146	Acyl-CoA dehydrogenase; Region: ACAD; cd00567
511145005147	active site
511145005148	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
511145005149	Cupin domain; Region: Cupin_2; pfam07883
511145005150	Winged helix DNA-binding domain (DUF1495); Region: DUF1495; cl01336
511145005151	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145005152	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
511145005153	Ligand binding site [chemical binding]; other site
511145005154	electron transfer flavoprotein subunit YdiR; Provisional; Region: PRK11916
511145005155	Electron transfer flavoprotein domain; Region: ETF; pfam01012
511145005156	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
511145005157	oxidoreductase; Provisional; Region: PRK10015
511145005158	putative oxidoreductase FixC; Provisional; Region: PRK10157
511145005159	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
511145005160	short chain acyl-CoA synthetase; Reviewed; Region: PRK06087
511145005161	Cyclohexanecarboxylate-CoA ligase (also called cyclohex-1-ene-1-carboxylate:CoA ligase); Region: CHC_CoA_lg; cd05903
511145005162	acyl-activating enzyme (AAE) consensus motif; other site
511145005163	putative AMP binding site [chemical binding]; other site
511145005164	putative active site [active]
511145005165	putative CoA binding site [chemical binding]; other site
511145005166	phosphoenolpyruvate synthase; Validated; Region: PRK06464
511145005167	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
511145005168	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145005169	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
511145005170	PEP synthetase regulatory protein; Provisional; Region: PRK05339
511145005171	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12756
511145005172	Hemin uptake protein [Inorganic ion transport and metabolism]; Region: HemP; COG4256
511145005173	hypothetical protein; Validated; Region: PRK00029
511145005174	c-di-GMP phosphodiesterase class I (EAL domain) [Signal    transduction mechanisms]; Region: Rtn; COG2200
511145005175	NlpC/P60 family; Region: NLPC_P60; pfam00877
511145005176	ABC-type cobalamin transport system, ATPase component [Coenzyme metabolism]; Region: BtuD; COG4138
511145005177	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
511145005178	Walker A/P-loop; other site
511145005179	ATP binding site [chemical binding]; other site
511145005180	Q-loop/lid; other site
511145005181	ABC transporter signature motif; other site
511145005182	Walker B; other site
511145005183	D-loop; other site
511145005184	H-loop/switch region; other site
511145005185	Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per...; Region: GSH_Peroxidase; cd00340
511145005186	catalytic residues [active]
511145005187	dimer interface [polypeptide binding]; other site
511145005188	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145005189	ABC-ATPase subunit  interface; other site
511145005190	dimer interface [polypeptide binding]; other site
511145005191	putative PBP binding regions; other site
511145005192	Alpha subunit of integration host factor (IHFA); Region: IHF_A; cd13835
511145005193	DNA binding site [nucleotide binding]
511145005194	dimer interface [polypeptide binding]; other site
511145005195	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
511145005196	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
511145005197	putative tRNA-binding site [nucleotide binding]; other site
511145005198	B3/4 domain; Region: B3_4; pfam03483
511145005199	tRNA synthetase B5 domain; Region: B5; smart00874
511145005200	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
511145005201	dimer interface [polypeptide binding]; other site
511145005202	motif 1; other site
511145005203	motif 3; other site
511145005204	motif 2; other site
511145005205	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
511145005206	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
511145005207	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
511145005208	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
511145005209	dimer interface [polypeptide binding]; other site
511145005210	motif 1; other site
511145005211	active site
511145005212	motif 2; other site
511145005213	motif 3; other site
511145005214	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
511145005215	23S rRNA binding site [nucleotide binding]; other site
511145005216	L21 binding site [polypeptide binding]; other site
511145005217	L13 binding site [polypeptide binding]; other site
511145005218	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
511145005219	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
511145005220	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
511145005221	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
511145005222	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
511145005223	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
511145005224	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
511145005225	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
511145005226	active site
511145005227	dimer interface [polypeptide binding]; other site
511145005228	motif 1; other site
511145005229	motif 2; other site
511145005230	motif 3; other site
511145005231	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
511145005232	anticodon binding site; other site
511145005233	Putative salt-induced outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG3137
511145005234	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
511145005235	putative substrate binding site [chemical binding]; other site
511145005236	putative ATP binding site [chemical binding]; other site
511145005237	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
511145005238	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3001
511145005239	Phosphotransferase enzyme family; Region: APH; pfam01636
511145005240	Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs)...; Region: APH_ChoK_like; cd05120
511145005241	active site
511145005242	substrate binding site [chemical binding]; other site
511145005243	ATP binding site [chemical binding]; other site
511145005244	YniB-like protein; Region: YniB; pfam14002
511145005245	2-deoxyglucose-6-phosphatase; Provisional; Region: PRK10826
511145005246	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
511145005247	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145005248	motif II; other site
511145005249	inner membrane protein; Provisional; Region: PRK11648
511145005250	Predicted Na+/dicarboxylate symporter [General function prediction only]; Region: COG1823
511145005251	Cell division activator CedA; Region: CedA; pfam10729
511145005252	hydroperoxidase II; Provisional; Region: katE; PRK11249
511145005253	Clade 2 of the heme-binding enzyme catalase; Region: catalase_clade_2; cd08155
511145005254	tetramer interface [polypeptide binding]; other site
511145005255	heme binding pocket [chemical binding]; other site
511145005256	Type 1 glutamine amidotransferase (GATase1)-like domain found in at the C-terminal of several large catalases; Region: GATase1_catalase; cd03132
511145005257	domain interactions; other site
511145005258	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
511145005259	putative active site [active]
511145005260	YdjC motif; other site
511145005261	Mg binding site [ion binding]; other site
511145005262	putative homodimer interface [polypeptide binding]; other site
511145005263	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
511145005264	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
511145005265	NAD binding site [chemical binding]; other site
511145005266	sugar binding site [chemical binding]; other site
511145005267	divalent metal binding site [ion binding]; other site
511145005268	tetramer (dimer of dimers) interface [polypeptide binding]; other site
511145005269	dimer interface [polypeptide binding]; other site
511145005270	DNA-binding transcriptional regulator ChbR; Provisional; Region: PRK10296
511145005271	Cupin domain; Region: Cupin_2; cl17218
511145005272	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145005273	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
511145005274	methionine cluster; other site
511145005275	active site
511145005276	phosphorylation site [posttranslational modification]
511145005277	metal binding site [ion binding]; metal-binding site
511145005278	PTS system N,N'-diacetylchitobiose-specific transporter subunit IIC; Provisional; Region: PRK10297
511145005279	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
511145005280	active site
511145005281	P-loop; other site
511145005282	phosphorylation site [posttranslational modification]
511145005283	DNA-binding transcriptional activator OsmE; Provisional; Region: PRK11251
511145005284	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
511145005285	homodimer interface [polypeptide binding]; other site
511145005286	NAD binding pocket [chemical binding]; other site
511145005287	ATP binding pocket [chemical binding]; other site
511145005288	Mg binding site [ion binding]; other site
511145005289	active-site loop [active]
511145005290	nucleotide excision repair endonuclease; Provisional; Region: PRK10545
511145005291	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
511145005292	GIY-YIG motif/motif A; other site
511145005293	active site
511145005294	catalytic site [active]
511145005295	putative DNA binding site [nucleotide binding]; other site
511145005296	metal binding site [ion binding]; metal-binding site
511145005297	hypothetical protein; Provisional; Region: PRK11396
511145005298	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
511145005299	dimer interface [polypeptide binding]; other site
511145005300	Peptidase M14 Succinylglutamate desuccinylase (ASTE) subfamily; Region: M14_ASTE; cd03855
511145005301	Succinylglutamate desuccinylase / Aspartoacylase family; Region: AstE_AspA; pfam04952
511145005302	putative active site [active]
511145005303	Zn binding site [ion binding]; other site
511145005304	succinylarginine dihydrolase; Provisional; Region: PRK13281
511145005305	N-succinylglutamate 5-semialdehyde dehydrogenase, AstD-like; Region: ALDH_SGSD_AstD; cd07095
511145005306	NAD(P) binding site [chemical binding]; other site
511145005307	catalytic residues [active]
511145005308	arginine succinyltransferase; Provisional; Region: PRK10456
511145005309	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145005310	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145005311	inhibitor-cofactor binding pocket; inhibition site
511145005312	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145005313	catalytic residue [active]
511145005314	Escherichia coli exonuclease III (ExoIII) and Neisseria meningitides NExo-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: ExoIII-like_AP-endo; cd09086
511145005315	putative catalytic site [active]
511145005316	putative phosphate binding site [ion binding]; other site
511145005317	active site
511145005318	metal binding site A [ion binding]; metal-binding site
511145005319	DNA binding site [nucleotide binding]
511145005320	putative AP binding site [nucleotide binding]; other site
511145005321	putative metal binding site B [ion binding]; other site
511145005322	Uncharacterized conserved protein [Function unknown]; Region: COG0398
511145005323	Uncharacterized conserved protein [Function unknown]; Region: COG0398
511145005324	Uncharacterized conserved protein [Function unknown]; Region: COG2128
511145005325	Carboxymuconolactone decarboxylase family; Region: CMD; pfam02627
511145005326	hypothetical protein; Provisional; Region: PRK11622
511145005327	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
511145005328	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4135
511145005329	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145005330	putative PBP binding loops; other site
511145005331	ABC-ATPase subunit interface; other site
511145005332	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4136
511145005333	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145005334	Walker A/P-loop; other site
511145005335	ATP binding site [chemical binding]; other site
511145005336	Q-loop/lid; other site
511145005337	ABC transporter signature motif; other site
511145005338	Walker B; other site
511145005339	D-loop; other site
511145005340	H-loop/switch region; other site
511145005341	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
511145005342	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
511145005343	active site residue [active]
511145005344	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
511145005345	active site residue [active]
511145005346	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
511145005347	The MutT pyrophosphohydrolase is a prototypical Nudix hydrolase that catalyzes the hydrolysis of nucleoside and deoxynucleoside triphosphates (NTPs and dNTPs) by substitution at a beta-phosphorus to yield a nucleotide monophosphate (NMP) and inorganic...; Region: MutT_pyrophosphohydrolase; cd03425
511145005348	active site
511145005349	8-oxo-dGMP binding site [chemical binding]; other site
511145005350	nudix motif; other site
511145005351	metal binding site [ion binding]; metal-binding site
511145005352	Protein of unknown function (DUF1496); Region: DUF1496; pfam07383
511145005353	glutamate dehydrogenase; Provisional; Region: PRK09414
511145005354	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
511145005355	NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; Region: NAD_bind_2_Glu_DH; cd05313
511145005356	NAD(P) binding site [chemical binding]; other site
511145005357	hypothetical protein; Provisional; Region: PRK11380
511145005358	DNA topoisomerase III; Provisional; Region: PRK07726
511145005359	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
511145005360	active site
511145005361	putative interdomain interaction site [polypeptide binding]; other site
511145005362	putative metal-binding site [ion binding]; other site
511145005363	putative nucleotide binding site [chemical binding]; other site
511145005364	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
511145005365	domain I; other site
511145005366	DNA binding groove [nucleotide binding]
511145005367	phosphate binding site [ion binding]; other site
511145005368	domain II; other site
511145005369	domain III; other site
511145005370	nucleotide binding site [chemical binding]; other site
511145005371	catalytic site [active]
511145005372	domain IV; other site
511145005373	selenophosphate synthetase; Provisional; Region: PRK00943
511145005374	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
511145005375	dimerization interface [polypeptide binding]; other site
511145005376	putative ATP binding site [chemical binding]; other site
511145005377	Nitroreductase-like family which includes NADH oxidase and arsenite oxidiase. NADH oxidase catalyses the oxidation of NAD(P)H and accepts a wide broad range of compounds as electron acceptors, such as nitrocompound. Arsenite oxidase in a...; Region: Arsenite_oxidase; cd02135
511145005378	putative FMN binding site [chemical binding]; other site
511145005379	protease 4; Provisional; Region: PRK10949
511145005380	Signal peptide peptidase A (SppA) 67K type, a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_67K_type; cd07018
511145005381	tandem repeat interface [polypeptide binding]; other site
511145005382	oligomer interface [polypeptide binding]; other site
511145005383	active site residues [active]
511145005384	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_SppA_1; cd07019
511145005385	tandem repeat interface [polypeptide binding]; other site
511145005386	oligomer interface [polypeptide binding]; other site
511145005387	active site residues [active]
511145005388	cytoplasmic asparaginase I; Provisional; Region: ansA; PRK09461
511145005389	Type I (cytosolic) bacterial L-asparaginase; Region: L-asparaginase_I; cd08963
511145005390	active site
511145005391	homodimer interface [polypeptide binding]; other site
511145005392	Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is...; Region: nicotinamidase; cd01011
511145005393	catalytic triad [active]
511145005394	metal binding site [ion binding]; metal-binding site
511145005395	conserved cis-peptide bond; other site
511145005396	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005397	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
511145005398	putative substrate translocation pore; other site
511145005399	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
511145005400	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
511145005401	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145005402	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145005403	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145005404	active site
511145005405	catalytic tetrad [active]
511145005406	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
511145005407	substrate binding site [chemical binding]; other site
511145005408	ATP binding site [chemical binding]; other site
511145005409	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
511145005410	intersubunit interface [polypeptide binding]; other site
511145005411	active site
511145005412	zinc binding site [ion binding]; other site
511145005413	Na+ binding site [ion binding]; other site
511145005414	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145005415	Sorbitol dehydrogenase; Region: sorbitol_DH; cd05285
511145005416	inhibitor binding site; inhibition site
511145005417	catalytic Zn binding site [ion binding]; other site
511145005418	structural Zn binding site [ion binding]; other site
511145005419	NADP binding site [chemical binding]; other site
511145005420	tetramer interface [polypeptide binding]; other site
511145005421	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005422	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145005423	putative substrate translocation pore; other site
511145005424	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145005425	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
511145005426	putative NAD(P) binding site [chemical binding]; other site
511145005427	catalytic Zn binding site [ion binding]; other site
511145005428	structural Zn binding site [ion binding]; other site
511145005429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3139
511145005430	methionine sulfoxide reductase B; Provisional; Region: PRK00222
511145005431	glyceraldehyde-3-phosphate dehydrogenase A; Provisional; Region: gapA; PRK15425
511145005432	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
511145005433	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
511145005434	D-hexose-6-phosphate epimerase-like; Region: D-hex-6-P-epi_like; cd09020
511145005435	active site
511145005436	phosphate binding residues; other site
511145005437	catalytic residues [active]
511145005438	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145005439	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145005440	active site
511145005441	catalytic tetrad [active]
511145005442	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
511145005443	PrkA family serine protein kinase; Provisional; Region: PRK15455
511145005444	PrkA AAA domain; Region: AAA_PrkA; pfam08298
511145005445	Walker A motif; other site
511145005446	ATP binding site [chemical binding]; other site
511145005447	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
511145005448	Uncharacterized conserved protein [Function unknown]; Region: COG2718
511145005449	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
511145005450	metal ion-dependent adhesion site (MIDAS); other site
511145005451	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145005452	metal binding site [ion binding]; metal-binding site
511145005453	active site
511145005454	I-site; other site
511145005455	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145005456	metal binding site [ion binding]; metal-binding site
511145005457	active site
511145005458	I-site; other site
511145005459	YeaK is an uncharacterized Echerichia coli protein with a YbaK-like domain of unknown function.  The YbaK-like domain family includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting...; Region: YeaK; cd04336
511145005460	putative deacylase active site [active]
511145005461	Predicted membrane protein [Function unknown]; Region: COG2707
511145005462	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145005463	cyanate transporter; Region: CynX; TIGR00896
511145005464	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005465	putative substrate translocation pore; other site
511145005466	Uncharacterized conserved protein [Function unknown]; Region: COG3189
511145005467	Putative hemolysin [General function prediction only]; Region: Hlx; COG3042
511145005468	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145005469	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145005470	metal binding site [ion binding]; metal-binding site
511145005471	active site
511145005472	I-site; other site
511145005473	hypothetical protein; Provisional; Region: PRK14760
511145005474	hypothetical protein; Provisional; Region: PRK10457
511145005475	Domain of unknown function (DUF1869); Region: DUF1869; pfam08956
511145005476	Uncharacterized protein/domain, possibly involved in tellurite resistance [Inorganic ion transport and metabolism]; Region: TehB; COG3615
511145005477	leucine export protein LeuE; Provisional; Region: PRK10958
511145005478	transcriptional activator TtdR; Provisional; Region: PRK09801
511145005479	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145005480	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
511145005481	putative effector binding pocket; other site
511145005482	putative dimerization interface [polypeptide binding]; other site
511145005483	Isocitrate/isopropylmalate dehydrogenase; Region: Iso_dh; cl00445
511145005484	putative transporter; Provisional; Region: PRK09950
511145005485	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
511145005486	Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable...; Region: Rieske_RO_Alpha_N; cd03469
511145005487	[2Fe-2S] cluster binding site [ion binding]; other site
511145005488	C-terminal catalytic domain of the oxygenase alpha subunit of an uncharacterized subgroup of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases; Region: RHO_alpha_C_2; cd08886
511145005489	putative alpha subunit interface [polypeptide binding]; other site
511145005490	putative active site [active]
511145005491	putative substrate binding site [chemical binding]; other site
511145005492	Fe binding site [ion binding]; other site
511145005493	Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 [Energy production and conversion]; Region: Hmp; COG1018
511145005494	Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal  ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur; Region: PDR_like; cd06185
511145005495	FMN-binding pocket [chemical binding]; other site
511145005496	flavin binding motif; other site
511145005497	phosphate binding motif [ion binding]; other site
511145005498	beta-alpha-beta structure motif; other site
511145005499	NAD binding pocket [chemical binding]; other site
511145005500	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145005501	catalytic loop [active]
511145005502	iron binding site [ion binding]; other site
511145005503	ribonuclease D; Provisional; Region: PRK10829
511145005504	DEDDy 3'-5' exonuclease domain of Ribonuclease D and similar proteins; Region: RNaseD_exo; cd06142
511145005505	catalytic site [active]
511145005506	putative active site [active]
511145005507	putative substrate binding site [chemical binding]; other site
511145005508	Helicase and RNase D C-terminal; Region: HRDC; smart00341
511145005509	long-chain-fatty-acid--CoA ligase; Validated; Region: PRK08974
511145005510	Prokaryotic long-chain fatty acid CoA synthetases similar to Escherichia coli FadD; Region: FC-FACS_FadD_like; cd05936
511145005511	acyl-activating enzyme (AAE) consensus motif; other site
511145005512	putative AMP binding site [chemical binding]; other site
511145005513	putative active site [active]
511145005514	putative CoA binding site [chemical binding]; other site
511145005515	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
511145005516	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
511145005517	Glycoprotease family; Region: Peptidase_M22; pfam00814
511145005518	Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair]; Region: DinG; COG1199
511145005519	CRISPR/Cas system-associated DinG family helicase Csf4; Region: Csf4_U; cd09708
511145005520	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
511145005521	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
511145005522	homotrimer interaction site [polypeptide binding]; other site
511145005523	putative active site [active]
511145005524	Domain of unknown function (DUF1889); Region: DUF1889; pfam08986
511145005525	hypothetical protein; Provisional; Region: PRK05114
511145005526	aminodeoxychorismate synthase subunit I; Provisional; Region: pabB; PRK15465
511145005527	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
511145005528	aminodeoxychorismate synthase, component I, bacterial clade; Region: pabB; TIGR00553
511145005529	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
511145005530	putative active site [active]
511145005531	putative CoA binding site [chemical binding]; other site
511145005532	nudix motif; other site
511145005533	metal binding site [ion binding]; metal-binding site
511145005534	L-serine deaminase; Provisional; Region: PRK15023
511145005535	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
511145005536	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
511145005537	phage resistance protein; Provisional; Region: PRK10551
511145005538	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
511145005539	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145005540	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
511145005541	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
511145005542	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
511145005543	Transporter associated domain; Region: CorC_HlyC; smart01091
511145005544	PTS system mannose-specific transporter subunits IIAB; Provisional; Region: PRK15088
511145005545	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
511145005546	active pocket/dimerization site; other site
511145005547	active site
511145005548	phosphorylation site [posttranslational modification]
511145005549	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
511145005550	active site
511145005551	phosphorylation site [posttranslational modification]
511145005552	PTS system mannose-specific transporter subunit IIC; Provisional; Region: PRK15065
511145005553	PTS system mannose-specific transporter subunit IID; Provisional; Region: PRK11103
511145005554	hypothetical protein; Provisional; Region: PRK02913
511145005555	hypothetical protein; Provisional; Region: PRK11469
511145005556	Domain of unknown function DUF; Region: DUF204; pfam02659
511145005557	Domain of unknown function DUF; Region: DUF204; pfam02659
511145005558	Methyltransferase domain; Region: Methyltransf_31; pfam13847
511145005559	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005560	S-adenosylmethionine binding site [chemical binding]; other site
511145005561	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145005562	DNA-binding site [nucleotide binding]; DNA binding site
511145005563	RNA-binding motif; other site
511145005564	Protein of unknown function (DUF2627); Region: DUF2527; pfam10736
511145005565	YebO-like protein; Region: YebO; pfam13974
511145005566	PhoPQ regulatory protein; Provisional; Region: PRK10299
511145005567	YobH-like protein; Region: YobH; pfam13996
511145005568	DNA-binding transcriptional regulator KdgR; Provisional; Region: PRK15090
511145005569	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145005570	dimerization interface [polypeptide binding]; other site
511145005571	putative Zn2+ binding site [ion binding]; other site
511145005572	putative DNA binding site [nucleotide binding]; other site
511145005573	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145005574	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145005575	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145005576	putative substrate translocation pore; other site
511145005577	Predicted integral membrane protein [Function unknown]; Region: COG5521
511145005578	heat shock protein HtpX; Provisional; Region: PRK05457
511145005579	carboxy-terminal protease; Provisional; Region: PRK11186
511145005580	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
511145005581	protein binding site [polypeptide binding]; other site
511145005582	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
511145005583	Catalytic dyad [active]
511145005584	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
511145005585	ProP expression regulator; Provisional; Region: PRK04950
511145005586	putative RNA binding sites [nucleotide binding]; other site
511145005587	GAF domain-containing protein [Signal transduction mechanisms]; Region: COG1956
511145005588	integral membrane protein, PqiA family; Region: pqiA_fam; TIGR00155
511145005589	Paraquat-inducible protein A; Region: PqiA; pfam04403
511145005590	Paraquat-inducible protein A; Region: PqiA; pfam04403
511145005591	Paraquat-inducible protein B [General function prediction only]; Region: PqiB; COG3008
511145005592	mce related protein; Region: MCE; pfam02470
511145005593	mce related protein; Region: MCE; pfam02470
511145005594	mce related protein; Region: MCE; pfam02470
511145005595	mce related protein; Region: MCE; pfam02470
511145005596	mce related protein; Region: MCE; pfam02470
511145005597	mce related protein; Region: MCE; pfam02470
511145005598	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
511145005599	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005600	S-adenosylmethionine binding site [chemical binding]; other site
511145005601	Uncharacterized conserved protein [Function unknown]; Region: COG3270
511145005602	Protein of unknown function (DUF1480); Region: DUF1480; pfam07351
511145005603	Protein of unknown function (DUF1482); Region: DUF1482; pfam07358
511145005604	serine/threonine protein phosphatase 1; Provisional; Region: pphA; PRK11439
511145005605	Protein of unknown function (DUF2511); Region: DUF2511; pfam10709
511145005606	Putative copper export protein [Inorganic ion transport and metabolism]; Region: PcoD; COG1276
511145005607	hypothetical protein; Provisional; Region: PRK10301
511145005608	DNA polymerase III subunit theta; Reviewed; Region: PRK10969
511145005609	Predicted amidohydrolase [General function prediction only]; Region: COG0388
511145005610	exodeoxyribonuclease X; Provisional; Region: PRK07983
511145005611	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
511145005612	active site
511145005613	catalytic site [active]
511145005614	substrate binding site [chemical binding]; other site
511145005615	protease 2; Provisional; Region: PRK10115
511145005616	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
511145005617	Protein of unknown function (DUF533); Region: DUF533; pfam04391
511145005618	tellurium resistance terB-like protein, subgroup 3; Region: terB_like_YebE; cd07178
511145005619	putative metal binding site [ion binding]; other site
511145005620	hypothetical protein; Provisional; Region: PRK13680
511145005621	DNA damage-inducible protein YebG; Provisional; Region: PRK10061
511145005622	phosphoribosylglycinamide formyltransferase 2; Validated; Region: purT; PRK09288
511145005623	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
511145005624	ATP-grasp domain; Region: ATP-grasp; pfam02222
511145005625	Entner-Doudoroff aldolase; Region: eda; TIGR01182
511145005626	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
511145005627	active site
511145005628	intersubunit interface [polypeptide binding]; other site
511145005629	catalytic residue [active]
511145005630	phosphogluconate dehydratase; Validated; Region: PRK09054
511145005631	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
511145005632	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
511145005633	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
511145005634	DNA-binding transcriptional regulator HexR; Provisional; Region: PRK11302
511145005635	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
511145005636	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
511145005637	putative active site [active]
511145005638	pyruvate kinase; Provisional; Region: PRK05826
511145005639	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
511145005640	domain interfaces; other site
511145005641	active site
511145005642	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
511145005643	putative acyl-acceptor binding pocket; other site
511145005644	putative peptidase; Provisional; Region: PRK11649
511145005645	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
511145005646	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145005647	Peptidase family M23; Region: Peptidase_M23; pfam01551
511145005648	Zinc binding protein ZnuA. These proteins have been shown to function as initial receptors in the ABC uptake of Zn2+.  They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism; Region: ZnuA; cd01019
511145005649	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
511145005650	metal binding site [ion binding]; metal-binding site
511145005651	high-affinity zinc transporter ATPase; Reviewed; Region: znuC; PRK09544
511145005652	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
511145005653	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145005654	ABC-ATPase subunit  interface; other site
511145005655	dimer interface [polypeptide binding]; other site
511145005656	putative PBP binding regions; other site
511145005657	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
511145005658	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145005659	Walker A motif; other site
511145005660	ATP binding site [chemical binding]; other site
511145005661	Walker B motif; other site
511145005662	arginine finger; other site
511145005663	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
511145005664	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
511145005665	RuvA N terminal domain; Region: RuvA_N; pfam01330
511145005666	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
511145005667	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
511145005668	hypothetical protein; Provisional; Region: PRK11470
511145005669	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
511145005670	active site
511145005671	putative DNA-binding cleft [nucleotide binding]; other site
511145005672	dimer interface [polypeptide binding]; other site
511145005673	hypothetical protein; Validated; Region: PRK00110
511145005674	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_7; cd04664
511145005675	nudix motif; other site
511145005676	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
511145005677	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
511145005678	dimer interface [polypeptide binding]; other site
511145005679	anticodon binding site; other site
511145005680	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
511145005681	homodimer interface [polypeptide binding]; other site
511145005682	motif 1; other site
511145005683	active site
511145005684	motif 2; other site
511145005685	GAD domain; Region: GAD; pfam02938
511145005686	motif 3; other site
511145005687	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
511145005688	catalytic triad [active]
511145005689	conserved cis-peptide bond; other site
511145005690	hypothetical protein; Provisional; Region: PRK10302
511145005691	Uncharacterized relative of glutathione S-transferase, MAPEG superfamily [General function prediction only]; Region: COG3788
511145005692	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005693	S-adenosylmethionine binding site [chemical binding]; other site
511145005694	tRNA (mo5U34)-methyltransferase; Region: TIGR00452
511145005695	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005696	S-adenosylmethionine binding site [chemical binding]; other site
511145005697	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
511145005698	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
511145005699	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
511145005700	molybdopterin cofactor binding site [chemical binding]; other site
511145005701	substrate binding site [chemical binding]; other site
511145005702	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
511145005703	molybdopterin cofactor binding site; other site
511145005704	NapC/NirT cytochrome c family, N-terminal region; Region: Cytochrom_NNT; pfam03264
511145005705	trimethylamine-N-oxide reductase c-type cytochrome TorC; Region: torC; TIGR02162
511145005706	copper homeostasis protein CutC; Provisional; Region: PRK11572
511145005707	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_4; cd07268
511145005708	putative metal binding site [ion binding]; other site
511145005709	Arginyl tRNA synthetase N terminal dom; Region: Arg_tRNA_synt_N; smart01016
511145005710	arginyl-tRNA synthetase; Region: argS; TIGR00456
511145005711	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
511145005712	active site
511145005713	HIGH motif; other site
511145005714	KMSK motif region; other site
511145005715	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
511145005716	tRNA binding surface [nucleotide binding]; other site
511145005717	anticodon binding site; other site
511145005718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3755
511145005719	Flagellar protein FlhE; Region: FlhE; pfam06366
511145005720	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
511145005721	FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167
511145005722	chemotaxis regulator CheZ; Provisional; Region: PRK11166
511145005723	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145005724	active site
511145005725	phosphorylation site [posttranslational modification]
511145005726	intermolecular recognition site; other site
511145005727	dimerization interface [polypeptide binding]; other site
511145005728	chemotaxis-specific methylesterase; Provisional; Region: PRK00742
511145005729	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145005730	active site
511145005731	phosphorylation site [posttranslational modification]
511145005732	intermolecular recognition site; other site
511145005733	dimerization interface [polypeptide binding]; other site
511145005734	CheB methylesterase; Region: CheB_methylest; pfam01339
511145005735	chemotaxis methyltransferase CheR; Provisional; Region: PRK10611
511145005736	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
511145005737	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145005738	S-adenosylmethionine binding site [chemical binding]; other site
511145005739	methyl-accepting protein IV; Provisional; Region: PRK09793
511145005740	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
511145005741	dimer interface [polypeptide binding]; other site
511145005742	ligand binding site [chemical binding]; other site
511145005743	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145005744	dimerization interface [polypeptide binding]; other site
511145005745	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
511145005746	dimer interface [polypeptide binding]; other site
511145005747	putative CheW interface [polypeptide binding]; other site
511145005748	methyl-accepting chemotaxis protein II; Provisional; Region: PRK15048
511145005749	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
511145005750	dimer interface [polypeptide binding]; other site
511145005751	ligand binding site [chemical binding]; other site
511145005752	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145005753	dimerization interface [polypeptide binding]; other site
511145005754	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
511145005755	dimer interface [polypeptide binding]; other site
511145005756	putative CheW interface [polypeptide binding]; other site
511145005757	CheW, a small regulator protein, unique to the chemotaxis signalling in prokaryotes and archea. CheW interacts with the histidine kinase CheA, most likely with the related regulatory domain of CheA. CheW is proposed to form signalling arrays together...; Region: CheW; cd00732
511145005758	putative CheA interaction surface; other site
511145005759	chemotaxis protein CheA; Provisional; Region: PRK10547
511145005760	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145005761	putative binding surface; other site
511145005762	active site
511145005763	CheY binding; Region: CheY-binding; pfam09078
511145005764	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
511145005765	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145005766	ATP binding site [chemical binding]; other site
511145005767	Mg2+ binding site [ion binding]; other site
511145005768	G-X-G motif; other site
511145005769	CheA regulatory domain; CheA is a histidine protein kinase present in bacteria and archea. Activated by the chemotaxis receptor a histidine phosphoryl group from CheA is passed directly to an aspartate in the response regulator CheY. This signalling...; Region: CheA_reg; cd00731
511145005770	flagellar motor protein MotB; Validated; Region: motB; PRK09041
511145005771	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
511145005772	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
511145005773	ligand binding site [chemical binding]; other site
511145005774	flagellar motor protein MotA; Validated; Region: PRK09110
511145005775	transcriptional activator FlhC; Provisional; Region: PRK12722
511145005776	transcriptional activator FlhD; Provisional; Region: PRK02909
511145005777	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145005778	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145005779	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145005780	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145005781	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145005782	Ligand Binding Site [chemical binding]; other site
511145005783	alpha,alpha-trehalose-phosphate synthase [UDP-forming]; Region: trehalose_OtsA; TIGR02400
511145005784	Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a...; Region: GT1_TPS; cd03788
511145005785	active site
511145005786	homotetramer interface [polypeptide binding]; other site
511145005787	trehalose-6-phosphate phosphatase; Provisional; Region: PRK10187
511145005788	HAD-superfamily hydrolase, subfamily IIB; Region: HAD-SF-IIB; TIGR01484
511145005789	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145005790	TM-ABC transporter signature motif; other site
511145005791	L-arabinose transporter ATP-binding protein; Provisional; Region: araG; PRK11288
511145005792	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145005793	Walker A/P-loop; other site
511145005794	ATP binding site [chemical binding]; other site
511145005795	Q-loop/lid; other site
511145005796	ABC transporter signature motif; other site
511145005797	Walker B; other site
511145005798	D-loop; other site
511145005799	H-loop/switch region; other site
511145005800	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145005801	Periplasmic binding proteins and sugar binding domain of LacI family; Region: Peripla_BP_1; pfam00532
511145005802	Periplasmic L-arabinose-binding protein (ABP), a member of a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein superfamily; Region: PBP1_arabinose_binding; cd01540
511145005803	ligand binding site [chemical binding]; other site
511145005804	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
511145005805	Ferritin-like domain; Region: Ferritin; pfam00210
511145005806	ferroxidase diiron center [ion binding]; other site
511145005807	Protein of unknown function (DUF2766); Region: DUF2766; pfam10964
511145005808	YecR-like lipoprotein; Region: YecR; pfam13992
511145005809	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
511145005810	Ferritin-like domain; Region: Ferritin; pfam00210
511145005811	ferroxidase diiron center [ion binding]; other site
511145005812	probable metal-binding protein; Region: matur_matur; TIGR03853
511145005813	tyrosine transporter TyrP; Provisional; Region: PRK15132
511145005814	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145005815	hypothetical protein; Provisional; Region: PRK10396
511145005816	yecA family protein; Region: ygfB_yecA; TIGR02292
511145005817	SEC-C motif; Region: SEC-C; cl19389
511145005818	phosphatidylglycerophosphate synthetase; Provisional; Region: PRK10832
511145005819	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
511145005820	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
511145005821	GIY-YIG motif/motif A; other site
511145005822	active site
511145005823	catalytic site [active]
511145005824	putative DNA binding site [nucleotide binding]; other site
511145005825	metal binding site [ion binding]; metal-binding site
511145005826	UvrB/uvrC motif; Region: UVR; pfam02151
511145005827	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
511145005828	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
511145005829	response regulator; Provisional; Region: PRK09483
511145005830	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145005831	active site
511145005832	phosphorylation site [posttranslational modification]
511145005833	intermolecular recognition site; other site
511145005834	dimerization interface [polypeptide binding]; other site
511145005835	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145005836	DNA binding residues [nucleotide binding]
511145005837	dimerization interface [polypeptide binding]; other site
511145005838	hypothetical protein; Provisional; Region: PRK10613
511145005839	DNA-binding transcriptional activator SdiA; Provisional; Region: PRK10188
511145005840	Autoinducer binding domain; Region: Autoind_bind; pfam03472
511145005841	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145005842	DNA binding residues [nucleotide binding]
511145005843	dimerization interface [polypeptide binding]; other site
511145005844	putative amino-acid ABC transporter ATP-binding protein YecC; Provisional; Region: PRK11264
511145005845	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
511145005846	Walker A/P-loop; other site
511145005847	ATP binding site [chemical binding]; other site
511145005848	Q-loop/lid; other site
511145005849	ABC transporter signature motif; other site
511145005850	Walker B; other site
511145005851	D-loop; other site
511145005852	H-loop/switch region; other site
511145005853	amino acid ABC transporter permease; Provisional; Region: PRK15100
511145005854	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145005855	dimer interface [polypeptide binding]; other site
511145005856	conserved gate region; other site
511145005857	putative PBP binding loops; other site
511145005858	ABC-ATPase subunit interface; other site
511145005859	Aminocyclopropane-1-carboxylate deaminase (ACCD): Pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of 1-aminocyclopropane-L-carboxylate (ACC), a precursor of the plant hormone ethylene, to alpha-ketobutyrate and ammonia; Region: ACCD; cd06449
511145005860	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145005861	catalytic residue [active]
511145005862	cystine transporter subunit; Provisional; Region: PRK11260
511145005863	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145005864	substrate binding pocket [chemical binding]; other site
511145005865	membrane-bound complex binding site; other site
511145005866	hinge residues; other site
511145005867	flagella biosynthesis protein FliZ; Provisional; Region: PRK11582
511145005868	flagellar biosynthesis sigma factor; Validated; Region: fliA; PRK06986
511145005869	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145005870	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
511145005871	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145005872	DNA binding residues [nucleotide binding]
511145005873	flagellin; Validated; Region: PRK08026
511145005874	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
511145005875	Flagellin D3 domain; Region: Flagellin_D3; pfam08884
511145005876	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
511145005877	flagellar capping protein; Reviewed; Region: fliD; PRK08032
511145005878	Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465
511145005879	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
511145005880	flagellar biosynthetic protein FliS; Region: fliS; TIGR00208
511145005881	flagellar biosynthesis protein FliT; Provisional; Region: PRK10548
511145005882	cytoplasmic alpha-amylase; Reviewed; Region: PRK09441
511145005883	Alpha amylase catalytic domain found in bacterial and fungal Alpha amylases (also called 1,4-alpha-D-glucan-4-glucanohydrolase); Region: AmyAc_bac_fung_AmyA; cd11318
511145005884	active site
511145005885	Na/Ca binding site [ion binding]; other site
511145005886	catalytic site [active]
511145005887	lipoprotein; Provisional; Region: PRK10397
511145005888	putative inner membrane protein; Provisional; Region: PRK11099
511145005889	Predicted transporter component [General function prediction only]; Region: COG2391
511145005890	YedF is a bacterial SirA-like protein of unknown function.  SirA  (also known as UvrY,  and YhhP) belongs to a family of a two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system...; Region: YedF; cd03422
511145005891	CPxP  motif; other site
511145005892	hypothetical protein; Provisional; Region: PRK09951
511145005893	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
511145005894	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145005895	Coenzyme A binding pocket [chemical binding]; other site
511145005896	flagellar hook-basal body complex protein FliE; Region: fliE; TIGR00205
511145005897	flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); Region: fliF; TIGR00206
511145005898	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; pfam01514
511145005899	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
511145005900	flagellar motor switch protein FliG; Region: fliG; TIGR00207
511145005901	FliG N-terminal domain; Region: FliG_N; pfam14842
511145005902	FliG middle domain; Region: FliG_M; pfam14841
511145005903	FliG C-terminal domain; Region: FliG_C; pfam01706
511145005904	flagellar assembly protein H; Validated; Region: fliH; PRK05687
511145005905	Essential protein Yae1, N terminal; Region: Yae1_N; pfam09811
511145005906	Flagellar assembly protein FliH; Region: FliH; pfam02108
511145005907	flagellum-specific ATP synthase; Validated; Region: fliI; PRK07960
511145005908	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
511145005909	Walker A motif/ATP binding site; other site
511145005910	Walker B motif; other site
511145005911	flagellar biosynthesis chaperone; Validated; Region: fliJ; PRK05689
511145005912	flagellar hook-length control protein; Provisional; Region: PRK10118
511145005913	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
511145005914	flagellar basal body-associated protein FliL; Reviewed; Region: fliL; PRK07021
511145005915	flagellar motor switch protein FliM; Validated; Region: fliM; PRK06666
511145005916	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
511145005917	flagellar motor switch protein FliN; Validated; Region: fliN; PRK07963
511145005918	flagellar biosynthesis protein FliO; Provisional; Region: PRK11486
511145005919	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
511145005920	flagellar biosynthesis protein FliQ; Validated; Region: fliQ; PRK05700
511145005921	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
511145005922	colanic acid capsular biosynthesis activation protein A; Provisional; Region: rcsA; PRK15411
511145005923	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145005924	DNA binding residues [nucleotide binding]
511145005925	dimerization interface [polypeptide binding]; other site
511145005926	hypothetical protein; Provisional; Region: PRK10708
511145005927	Protein of unknown function (DUF2525); Region: DUF2525; pfam10733
511145005928	mannosyl-3-phosphoglycerate phosphatase; Reviewed; Region: PRK03669
511145005929	mannosyl-3-phosphoglycerate phosphatase family; Region: HAD-SF-IIB-MPGP; TIGR01486
511145005930	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145005931	active site
511145005932	motif I; other site
511145005933	motif II; other site
511145005934	putative diguanylate cyclase YedQ; Provisional; Region: PRK15426
511145005935	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145005936	metal binding site [ion binding]; metal-binding site
511145005937	active site
511145005938	I-site; other site
511145005939	Uncharacterized small protein [Function unknown]; Region: COG5475
511145005940	hypothetical protein; Provisional; Region: PRK10062
511145005941	putative DMT superfamily transporter inner membrane protein; Provisional; Region: PRK11272
511145005942	EamA-like transporter family; Region: EamA; pfam00892
511145005943	EamA-like transporter family; Region: EamA; pfam00892
511145005944	Very Short Patch Repair (Vsr) Endonuclease. Endonucleases in DNA repair that recognize damaged DNA and cleave the phosphodiester backbone. Vsr endonucleases have a common endonuclease topology that has been tailored for recognition of TG mismatches; Region: Vsr; cd00221
511145005945	additional DNA contacts [nucleotide binding]; other site
511145005946	mismatch recognition site; other site
511145005947	active site
511145005948	zinc binding site [ion binding]; other site
511145005949	DNA intercalation site [nucleotide binding]; other site
511145005950	DNA cytosine methylase; Provisional; Region: PRK10458
511145005951	Cytosine-C5 specific DNA methylases; Methyl transfer reactions play an important role in many aspects of biology. Cytosine-specific DNA methylases are found both in prokaryotes and eukaryotes. DNA methylation, or the covalent addition of a methyl group...; Region: Cyt_C5_DNA_methylase; cd00315
511145005952	cofactor binding site; other site
511145005953	DNA binding site [nucleotide binding]
511145005954	substrate interaction site [chemical binding]; other site
511145005955	Predicted HD superfamily hydrolase [General function prediction only]; Region: COG1418
511145005956	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145005957	Zn2+ binding site [ion binding]; other site
511145005958	Mg2+ binding site [ion binding]; other site
511145005959	Dna-J like membrane chaperone protein; Provisional; Region: djlA; PRK09430
511145005960	chaperone protein HchA; Provisional; Region: PRK04155
511145005961	Type 1 glutamine amidotransferase (GATase1)-like domain found in Escherichia coli Hsp31 protein (EcHsp31); Region: GATase1_EcHsp31_like; cd03148
511145005962	dimer interface [polypeptide binding]; other site
511145005963	metal binding site [ion binding]; metal-binding site
511145005964	potential oxyanion hole; other site
511145005965	potential catalytic triad [active]
511145005966	conserved cys residue [active]
511145005967	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
511145005968	HAMP domain; Region: HAMP; pfam00672
511145005969	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145005970	dimer interface [polypeptide binding]; other site
511145005971	phosphorylation site [posttranslational modification]
511145005972	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145005973	ATP binding site [chemical binding]; other site
511145005974	Mg2+ binding site [ion binding]; other site
511145005975	G-X-G motif; other site
511145005976	transcriptional regulatory protein YedW; Provisional; Region: PRK11517
511145005977	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145005978	active site
511145005979	phosphorylation site [posttranslational modification]
511145005980	intermolecular recognition site; other site
511145005981	dimerization interface [polypeptide binding]; other site
511145005982	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145005983	DNA binding site [nucleotide binding]
511145005984	HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Region: TLP_HIUase; cd05822
511145005985	active site
511145005986	homotetramer interface [polypeptide binding]; other site
511145005987	Sulfite oxidase and related enzymes [General function prediction only]; Region: COG2041
511145005988	YedY_like molybdopterin cofactor (Moco) binding domain, a subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. Escherichia coli YedY has been propsed to form a heterodimer, consisting of a soluble catalytic subunit termed YedY; Region: YedY_like_Moco; cd02107
511145005989	Moco binding site; other site
511145005990	metal coordination site [ion binding]; other site
511145005991	putative sulfite oxidase subunit YedZ; Reviewed; Region: PRK05419
511145005992	zinc/cadmium-binding protein; Provisional; Region: PRK10306
511145005993	Cytochrome B561 [Energy production and conversion]; Region: CybB; COG3038
511145005994	DgsA anti-repressor MtfA; Provisional; Region: PRK15410
511145005995	putative invasin; Provisional; Region: PRK10177
511145005996	Protein of unknown function (DUF3442); Region: DUF3442; pfam11924
511145005997	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
511145005998	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145005999	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006000	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
511145006001	Bacterial Ig-like domain (group 1); Region: BID_1; smart00634
511145006002	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006003	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006004	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006005	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006006	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006007	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006008	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006009	Bacterial Ig-like domain (group 1); Region: Big_1; pfam02369
511145006010	shikimate transporter; Provisional; Region: PRK09952
511145006011	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006012	putative substrate translocation pore; other site
511145006013	AMP nucleosidase; Provisional; Region: PRK08292
511145006014	Bacterial AMP nucleoside phosphorylase N-terminus; Region: AMNp_N; pfam10423
511145006015	Nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pfs; COG0775
511145006016	hypothetical protein; Provisional; Region: PRK12378
511145006017	MATE family multidrug exporter; Provisional; Region: PRK10189
511145006018	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
511145006019	transcriptional regulator Cbl; Reviewed; Region: cbl; PRK12679
511145006020	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145006021	The C-terminal substrate binding domain of LysR-type transcriptional regulator Cbl, which is required for expression of sulfate starvation-inducible (ssi) genes, contains the type 2 periplasmic binding fold; Region: PBP2_Cbl; cd08444
511145006022	putative substrate binding site [chemical binding]; other site
511145006023	dimerization interface [polypeptide binding]; other site
511145006024	nitrogen assimilation transcriptional regulator; Provisional; Region: PRK11233
511145006025	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145006026	The C-teminal substrate binding domain of LysR-like nitrogen assimilation control (NAC) protein, contains the type 2 periplasmic binding fold; Region: PBP2_Nac; cd08433
511145006027	putative dimerization interface [polypeptide binding]; other site
511145006028	L,D-transpeptidase; Provisional; Region: PRK10190
511145006029	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
511145006030	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
511145006031	putative dimer interface [polypeptide binding]; other site
511145006032	active site pocket [active]
511145006033	putative cataytic base [active]
511145006034	cobalamin 5'-phosphate synthase/cobalamin synthase; Region: cobS; TIGR00317
511145006035	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
511145006036	homotrimer interface [polypeptide binding]; other site
511145006037	Walker A motif; other site
511145006038	GTP binding site [chemical binding]; other site
511145006039	Walker B motif; other site
511145006040	Transposase domain (DUF772); Region: DUF772; pfam05598
511145006041	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145006042	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145006043	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145006044	cryptic prophage CP4-44
511145006045	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145006046	HTH-like domain; Region: HTH_21; pfam13276
511145006047	Integrase core domain; Region: rve; pfam00665
511145006048	Integrase core domain; Region: rve_3; pfam13683
511145006049	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145006050	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145006051	Extended Signal Peptide of Type V secretion system; Region: ESPR; pfam13018
511145006052	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
511145006053	hypothetical protein; Provisional; Region: PRK09945
511145006054	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
511145006055	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
511145006056	Autotransporter beta-domain; Region: Autotransporter; smart00869
511145006057	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
511145006058	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
511145006059	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
511145006060	MPN+ (JAMM) motif; other site
511145006061	Zinc-binding site [ion binding]; other site
511145006062	Protein of unknown function (DUF987); Region: DUF987; pfam06174
511145006063	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
511145006064	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
511145006065	hypothetical protein; Provisional; Region: PRK05423
511145006066	Predicted membrane protein [Function unknown]; Region: COG1289
511145006067	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
511145006068	DNA gyrase inhibitor; Provisional; Region: PRK10016
511145006069	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
511145006070	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_S11; pfam00768
511145006071	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
511145006072	exonuclease I; Provisional; Region: sbcB; PRK11779
511145006073	N-terminal DEDDh 3'-5' exonuclease domain of Escherichia coli exonuclease I and similar proteins; Region: ExoI_N; cd06138
511145006074	active site
511145006075	catalytic site [active]
511145006076	substrate binding site [chemical binding]; other site
511145006077	Exonuclease C-terminal; Region: Exonuc_X-T_C; pfam08411
511145006078	SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain.  SirA (also known as UvrY,  and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this...; Region: SirA_YedF_YeeD; cd00291
511145006079	CPxP  motif; other site
511145006080	Predicted transporter component [General function prediction only]; Region: COG2391
511145006081	Sulphur transport; Region: Sulf_transp; cl19477
511145006082	Sulphur transport; Region: Sulf_transp; cl19477
511145006083	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
511145006084	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145006085	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145006086	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
511145006087	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145006088	dimerization interface [polypeptide binding]; other site
511145006089	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
511145006090	atypical (a) SDRs, subgroup 4; Region: SDR_a4; cd05266
511145006091	putative NAD(P) binding site [chemical binding]; other site
511145006092	Plasmid encoded toxin Txe; Region: Plasmid_Txe; pfam06769
511145006093	antitoxin YefM; Provisional; Region: PRK11409
511145006094	ATP phosphoribosyltransferase; Reviewed; Region: hisG; PRK00489
511145006095	ATP phosphoribosyltransferase; Region: hisG; TIGR00070
511145006096	ATP phosphoribosyltransferase, C-terminal domain; Region: HisG_C-term; TIGR03455
511145006097	Histidinol dehydrogenase [Amino acid transport and metabolism]; Region: HisD; COG0141
511145006098	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
511145006099	NAD binding site [chemical binding]; other site
511145006100	dimerization interface [polypeptide binding]; other site
511145006101	product binding site; other site
511145006102	substrate binding site [chemical binding]; other site
511145006103	zinc binding site [ion binding]; other site
511145006104	catalytic residues [active]
511145006105	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
511145006106	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145006107	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145006108	homodimer interface [polypeptide binding]; other site
511145006109	catalytic residue [active]
511145006110	imidazole glycerol-phosphate dehydratase/histidinol phosphatase; Provisional; Region: PRK05446
511145006111	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145006112	active site
511145006113	motif I; other site
511145006114	motif II; other site
511145006115	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
511145006116	putative active site pocket [active]
511145006117	4-fold oligomerization interface [polypeptide binding]; other site
511145006118	metal binding residues [ion binding]; metal-binding site
511145006119	3-fold/trimer interface [polypeptide binding]; other site
511145006120	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
511145006121	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
511145006122	putative active site [active]
511145006123	oxyanion strand; other site
511145006124	catalytic triad [active]
511145006125	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
511145006126	catalytic residues [active]
511145006127	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
511145006128	substrate binding site [chemical binding]; other site
511145006129	glutamase interaction surface [polypeptide binding]; other site
511145006130	Phosphoribosyl-AMP cyclohydrolase [Amino acid transport and metabolism]; Region: HisI; COG0139
511145006131	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
511145006132	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
511145006133	metal binding site [ion binding]; metal-binding site
511145006134	chain length determinant protein WzzB; Provisional; Region: PRK15471
511145006135	Chain length determinant protein; Region: Wzz; pfam02706
511145006136	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145006137	UDP-glucose 6-dehydrogenase; Provisional; Region: PRK15057
511145006138	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126
511145006139	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
511145006140	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
511145006141	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
511145006142	6-phosphogluconate dehydrogenase; Validated; Region: PRK09287
511145006143	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
511145006144	Transposase domain (DUF772); Region: DUF772; pfam05598
511145006145	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145006146	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145006147	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145006148	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
511145006149	Glycosyl transferases group 1; Region: Glycos_transf_1; pfam00534
511145006150	putative lipopolysaccharide biosynthesis O-acetyl transferase WbbJ; Provisional; Region: PRK09677
511145006151	Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the...; Region: LbH_MAT_like; cd04647
511145006152	trimer interface [polypeptide binding]; other site
511145006153	active site
511145006154	substrate binding site [chemical binding]; other site
511145006155	CoA binding site [chemical binding]; other site
511145006156	beta-1,6-galactofuranosyltransferase; Provisional; Region: PRK09814
511145006157	UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]; Region: Glf; COG0562
511145006158	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
511145006159	UDP-galactopyranose mutase; Region: GLF; pfam03275
511145006160	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
511145006161	Wzx, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_Wzx_like; cd13128
511145006162	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: rmlC; TIGR01221
511145006163	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
511145006164	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
511145006165	substrate binding site; other site
511145006166	tetramer interface; other site
511145006167	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
511145006168	RmlD substrate binding domain; Region: RmlD_sub_bind; pfam04321
511145006169	NADP binding site [chemical binding]; other site
511145006170	active site
511145006171	putative substrate binding site [chemical binding]; other site
511145006172	dTDP-glucose 4,6 dehydratase; Provisional; Region: PRK10084
511145006173	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
511145006174	NAD binding site [chemical binding]; other site
511145006175	substrate binding site [chemical binding]; other site
511145006176	homodimer interface [polypeptide binding]; other site
511145006177	active site
511145006178	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
511145006179	active site
511145006180	tetramer interface; other site
511145006181	putative colanic acid biosynthesis protein; Provisional; Region: wcaM; PRK10123
511145006182	colanic acid biosynthesis glycosyltransferase WcaL; Region: wcaL; TIGR04005
511145006183	This is a family of GT1 glycosyltransferases found specifically in certain bacteria. amsK in Erwinia amylovora, has been reported to be involved in the biosynthesis of amylovoran, a exopolysaccharide acting as a virulence factor; Region: GT1_amsK_like; cd03799
511145006184	putative ADP-binding pocket [chemical binding]; other site
511145006185	colanic acid biosynthesis pyruvyl transferase WcaK; Region: wcaK; TIGR04006
511145006186	colanic acid exporter; Provisional; Region: PRK10459
511145006187	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_tuaB_like; cd13127
511145006188	putative UDP-glucose lipid carrier transferase; Provisional; Region: PRK10124
511145006189	CoA-binding domain; Region: CoA_binding_3; pfam13727
511145006190	Bacterial sugar transferase; Region: Bac_transf; pfam02397
511145006191	phosphomannomutase CpsG; Provisional; Region: PRK15414
511145006192	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
511145006193	active site
511145006194	substrate binding site [chemical binding]; other site
511145006195	metal binding site [ion binding]; metal-binding site
511145006196	mannose-1-phosphate guanyltransferase; Provisional; Region: cpsB; PRK15460
511145006197	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
511145006198	Substrate binding site; other site
511145006199	Mannose-6-phosphate isomerase; Region: MannoseP_isomer; pfam01050
511145006200	colanic acid biosynthesis glycosyl transferase WcaI; Region: wcaI; TIGR04007
511145006201	This family is most closely related to the GT1 family of glycosyltransferases. wbuB in E. coli is involved in the biosynthesis of the O26 O-antigen.  It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase; Region: GT1_wbuB_like; cd03794
511145006202	GDP-mannose glycosyl hydrolase (AKA GDP-mannose mannosyl hydrolase (GDPMH)) is a member of the Nudix hydrolase superfamily. This class of enzymes is unique from other members of the superfamily in two aspects. First, it contains a modified Nudix...; Region: GDPMH; cd03430
511145006203	active site
511145006204	GDP-Mannose binding site [chemical binding]; other site
511145006205	dimer interface [polypeptide binding]; other site
511145006206	modified nudix motif
511145006207	metal binding site [ion binding]; metal-binding site
511145006208	GDP-fucose synthetase, extended (e) SDRs; Region: GDP_FS_SDR_e; cd05239
511145006209	GDP-4-keto-6-deoxymannose-3, 5-epimerase-4-reductase; Region: PLN02725
511145006210	NADP binding site [chemical binding]; other site
511145006211	active site
511145006212	putative substrate binding site [chemical binding]; other site
511145006213	GDP-D-mannose dehydratase [Cell envelope biogenesis, outer membrane]; Region: Gmd; COG1089
511145006214	GDP-mannose 4,6 dehydratase, extended (e) SDRs; Region: GDP_MD_SDR_e; cd05260
511145006215	NADP-binding site; other site
511145006216	homotetramer interface [polypeptide binding]; other site
511145006217	substrate binding site [chemical binding]; other site
511145006218	homodimer interface [polypeptide binding]; other site
511145006219	active site
511145006220	colanic acid biosynthesis acetyltransferase WcaF; Region: WcaF; TIGR04008
511145006221	wcaF-like: This group is composed of the protein product of the E. coli wcaF gene and similar proteins. WcaF is part of the gene cluster responsible for the biosynthesis of the extracellular polysaccharide colanic acid. The wcaF protein is predicted to...; Region: LbH_wcaF_like; cd05825
511145006222	putative trimer interface [polypeptide binding]; other site
511145006223	putative active site [active]
511145006224	putative substrate binding site [chemical binding]; other site
511145006225	putative CoA binding site [chemical binding]; other site
511145006226	putative glycosyl transferase; Provisional; Region: PRK10063
511145006227	WfgS and WfeV are involved in O-antigen biosynthesis; Region: GT_2_WfgS_like; cd06433
511145006228	metal-binding site
511145006229	putative colanic acid polymerase WcaD; Region: WcaD; TIGR04010
511145006230	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
511145006231	colanic acid biosynthesis glycosyl transferase WcaC; Region: WcaC; TIGR04015
511145006232	putative acyl transferase; Provisional; Region: PRK10191
511145006233	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
511145006234	trimer interface [polypeptide binding]; other site
511145006235	active site
511145006236	substrate binding site [chemical binding]; other site
511145006237	CoA binding site [chemical binding]; other site
511145006238	putative glycosyl transferase; Provisional; Region: PRK10018
511145006239	colanic acid biosynthesis glycosyl transferase WcaA; Region: WcaA; TIGR04017
511145006240	active site
511145006241	tyrosine kinase; Provisional; Region: PRK11519
511145006242	Chain length determinant protein; Region: Wzz; pfam02706
511145006243	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145006244	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
511145006245	Low molecular weight phosphatase family; Region: LMWPc; cd00115
511145006246	active site
511145006247	polysaccharide export protein Wza; Provisional; Region: PRK15078
511145006248	Polysaccharide biosynthesis/export protein; Region: Poly_export; pfam02563
511145006249	SLBB domain; Region: SLBB; pfam10531
511145006250	SLBB domain; Region: SLBB; pfam10531
511145006251	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
511145006252	FOG: CBS domain [General function prediction only]; Region: COG0517
511145006253	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
511145006254	Transporter associated domain; Region: CorC_HlyC; smart01091
511145006255	putative assembly protein; Provisional; Region: PRK10833
511145006256	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145006257	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145006258	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
511145006259	trimer interface [polypeptide binding]; other site
511145006260	active site
511145006261	Uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK), catalyzes the reversible phosphoryl transfer from ATP to uridine or cytidine to yield UMP or CMP. In the primidine nucleotide-salvage pathway; Region: UMPK; cd02023
511145006262	ATP-binding site [chemical binding]; other site
511145006263	Sugar specificity; other site
511145006264	Pyrimidine base specificity; other site
511145006265	Predicted integral membrane sensor domain [Signal transduction mechanisms]; Region: COG3447
511145006266	putative diguanylate cyclase; Provisional; Region: PRK09776
511145006267	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145006268	putative active site [active]
511145006269	heme pocket [chemical binding]; other site
511145006270	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145006271	putative active site [active]
511145006272	heme pocket [chemical binding]; other site
511145006273	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145006274	putative active site [active]
511145006275	heme pocket [chemical binding]; other site
511145006276	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145006277	metal binding site [ion binding]; metal-binding site
511145006278	active site
511145006279	I-site; other site
511145006280	Putative diguanylate phosphodiesterase; Region: EAL; smart00052
511145006281	3-methyl-adenine DNA glycosylase II; Provisional; Region: PRK10308
511145006282	AlkA N-terminal domain; Region: AlkA_N; smart01009
511145006283	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
511145006284	minor groove reading motif; other site
511145006285	helix-hairpin-helix signature motif; other site
511145006286	substrate binding pocket [chemical binding]; other site
511145006287	active site
511145006288	putative chaperone; Provisional; Region: PRK11678
511145006289	Escherichia coli YegD, a putative chaperone protein, and related proteins; Region: YegD_like; cd10231
511145006290	nucleotide binding site [chemical binding]; other site
511145006291	putative NEF/HSP70 interaction site [polypeptide binding]; other site
511145006292	SBD interface [polypeptide binding]; other site
511145006293	Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only]; Region: COG4248
511145006294	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
511145006295	substrate binding site [chemical binding]; other site
511145006296	activation loop (A-loop); other site
511145006297	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
511145006298	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3779
511145006299	Protein phosphatase 2C; Region: PP2C_2; pfam13672
511145006300	VWA subfamily: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subfamily; cd01464
511145006301	metal ion-dependent adhesion site (MIDAS); other site
511145006302	multidrug efflux system subunit MdtA; Provisional; Region: PRK11556
511145006303	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145006304	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145006305	multidrug efflux system subunit MdtB; Provisional; Region: PRK10503
511145006306	MMPL family; Region: MMPL; cl14618
511145006307	multidrug efflux system subunit MdtC; Provisional; Region: PRK10614
511145006308	MMPL family; Region: MMPL; cl14618
511145006309	MMPL family; Region: MMPL; cl14618
511145006310	putative transporter; Provisional; Region: PRK10504
511145006311	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006312	putative substrate translocation pore; other site
511145006313	signal transduction histidine-protein kinase BaeS; Provisional; Region: PRK10549
511145006314	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145006315	dimerization interface [polypeptide binding]; other site
511145006316	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145006317	dimer interface [polypeptide binding]; other site
511145006318	phosphorylation site [posttranslational modification]
511145006319	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145006320	ATP binding site [chemical binding]; other site
511145006321	Mg2+ binding site [ion binding]; other site
511145006322	G-X-G motif; other site
511145006323	DNA-binding transcriptional regulator BaeR; Provisional; Region: PRK10710
511145006324	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006325	active site
511145006326	phosphorylation site [posttranslational modification]
511145006327	intermolecular recognition site; other site
511145006328	dimerization interface [polypeptide binding]; other site
511145006329	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145006330	DNA binding site [nucleotide binding]
511145006331	Uncharacterized conserved protein [Function unknown]; Region: COG3422
511145006332	Domain of unknown function (DUF1508); Region: DUF1508; pfam07411
511145006333	putative protease; Provisional; Region: PRK15452
511145006334	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
511145006335	cryptic prophage PR-X
511145006336	DNA-binding transcriptional regulator; Provisional; Region: PRK09678
511145006337	lipid kinase; Reviewed; Region: PRK13054
511145006338	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
511145006339	Transposase; Region: HTH_Tnp_1; cl17663
511145006340	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145006341	putative transposase OrfB; Reviewed; Region: PHA02517
511145006342	HTH-like domain; Region: HTH_21; pfam13276
511145006343	Integrase core domain; Region: rve; pfam00665
511145006344	Integrase core domain; Region: rve_2; pfam13333
511145006345	galactitol-1-phosphate dehydrogenase; Provisional; Region: PRK10309
511145006346	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
511145006347	putative NAD(P) binding site [chemical binding]; other site
511145006348	catalytic Zn binding site [ion binding]; other site
511145006349	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
511145006350	active site
511145006351	P-loop; other site
511145006352	phosphorylation site [posttranslational modification]
511145006353	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145006354	active site
511145006355	phosphorylation site [posttranslational modification]
511145006356	D-tagatose-1,6-bisphosphate aldolase subunit GatZ; Provisional; Region: PRK15052
511145006357	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
511145006358	intersubunit interface [polypeptide binding]; other site
511145006359	active site
511145006360	zinc binding site [ion binding]; other site
511145006361	Na+ binding site [ion binding]; other site
511145006362	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
511145006363	putative active site; other site
511145006364	catalytic residue [active]
511145006365	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
511145006366	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006367	putative substrate translocation pore; other site
511145006368	ADP-ribosylglycohydrolase [Posttranslational modification, protein turnover, chaperones]; Region: DraG; COG1397
511145006369	YegV-like sugar kinase.  Found only in bacteria, YegV-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YegV_kinase_like; cd01944
511145006370	substrate binding site [chemical binding]; other site
511145006371	ATP binding site [chemical binding]; other site
511145006372	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
511145006373	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145006374	DNA-binding site [nucleotide binding]; DNA binding site
511145006375	UTRA domain; Region: UTRA; pfam07702
511145006376	Lyzozyme M1 (1,4-beta-N-acetylmuramidase) [Cell envelope biogenesis, outer membrane]; Region: Acm; COG3757
511145006377	YegX is an uncharacterized bacterial protein with a glycosyl hydrolase family 25 (GH25) catalytic domain that is similar in sequence to the CH-type (Chalaropsis-type) lysozymes of the GH25 family of endolysins; Region: GH25_YegX-like; cd06524
511145006378	active site
511145006379	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
511145006380	dimer interface [polypeptide binding]; other site
511145006381	substrate binding site [chemical binding]; other site
511145006382	ATP binding site [chemical binding]; other site
511145006383	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
511145006384	substrate binding site [chemical binding]; other site
511145006385	multimerization interface [polypeptide binding]; other site
511145006386	ATP binding site [chemical binding]; other site
511145006387	Transcriptional regulators RcnR and FrmR, and related domains; this domain family was previously known as part of DUF156; Region: RcnR-FrmR-like_DUF156; cd10153
511145006388	putative metal binding site [ion binding]; other site
511145006389	putative homodimer interface [polypeptide binding]; other site
511145006390	putative homotetramer interface [polypeptide binding]; other site
511145006391	putative homodimer-homodimer interface [polypeptide binding]; other site
511145006392	putative allosteric switch controlling residues; other site
511145006393	nickel/cobalt efflux protein RcnA; Provisional; Region: PRK10019
511145006394	Predicted integral membrane protein [Function unknown]; Region: COG5455
511145006395	putative fimbrial-like adhesin protein StcD; Provisional; Region: PRK15252
511145006396	fimbrial outer membrane usher protein; Provisional; Region: PRK15217
511145006397	PapC N-terminal domain; Region: PapC_N; pfam13954
511145006398	Outer membrane usher protein; Region: Usher; pfam00577
511145006399	PapC C-terminal domain; Region: PapC_C; pfam13953
511145006400	putative fimbrial assembly chaperone protein StcB; Provisional; Region: PRK15253
511145006401	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145006402	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145006403	Fimbrial protein; Region: Fimbrial; cl01416
511145006404	Protein of unknown function (DUF2574); Region: DUF2574; pfam10836
511145006405	antiporter inner membrane protein; Provisional; Region: PRK11670
511145006406	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
511145006407	Walker A motif; other site
511145006408	methionyl-tRNA synthetase; Reviewed; Region: metG; PRK00133
511145006409	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
511145006410	active site
511145006411	HIGH motif; other site
511145006412	KMSKS motif; other site
511145006413	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
511145006414	tRNA binding surface [nucleotide binding]; other site
511145006415	anticodon binding site; other site
511145006416	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
511145006417	dimer interface [polypeptide binding]; other site
511145006418	putative tRNA-binding site [nucleotide binding]; other site
511145006419	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
511145006420	MoxR-like ATPases [General function prediction only]; Region: COG0714
511145006421	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145006422	Walker A motif; other site
511145006423	ATP binding site [chemical binding]; other site
511145006424	Walker B motif; other site
511145006425	arginine finger; other site
511145006426	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
511145006427	metal ion-dependent adhesion site (MIDAS); other site
511145006428	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4808
511145006429	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4807
511145006430	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
511145006431	Protein of unknown function (DUF1456); Region: DUF1456; pfam07308
511145006432	putative two-component response-regulatory protein YehT; Provisional; Region: PRK11697
511145006433	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006434	active site
511145006435	phosphorylation site [posttranslational modification]
511145006436	intermolecular recognition site; other site
511145006437	dimerization interface [polypeptide binding]; other site
511145006438	LytTr DNA-binding domain; Region: LytTR; pfam04397
511145006439	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
511145006440	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
511145006441	GAF domain; Region: GAF; pfam01590
511145006442	Histidine kinase; Region: His_kinase; pfam06580
511145006443	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145006444	ATP binding site [chemical binding]; other site
511145006445	Mg2+ binding site [ion binding]; other site
511145006446	G-X-G motif; other site
511145006447	transcriptional regulator MirA; Provisional; Region: PRK15043
511145006448	Helix-Turn-Helix DNA binding domain of MlrA-like transcription regulators; Region: HTH_MlrA-like; cd04763
511145006449	DNA binding residues [nucleotide binding]
511145006450	hypothetical protein; Provisional; Region: PRK13681
511145006451	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
511145006452	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
511145006453	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145006454	dimer interface [polypeptide binding]; other site
511145006455	conserved gate region; other site
511145006456	putative PBP binding loops; other site
511145006457	ABC-ATPase subunit interface; other site
511145006458	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
511145006459	ATP-binding cassette domain of the osmoprotectant transporter; Region: ABC_OpuCA_Osmoprotection; cd03295
511145006460	Walker A/P-loop; other site
511145006461	ATP binding site [chemical binding]; other site
511145006462	Q-loop/lid; other site
511145006463	ABC transporter signature motif; other site
511145006464	Walker B; other site
511145006465	D-loop; other site
511145006466	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair; cd02205
511145006467	H-loop/switch region; other site
511145006468	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145006469	dimer interface [polypeptide binding]; other site
511145006470	conserved gate region; other site
511145006471	putative PBP binding loops; other site
511145006472	ABC-ATPase subunit interface; other site
511145006473	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
511145006474	beta-D-glucoside glucohydrolase; Provisional; Region: PRK15098
511145006475	Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; Region: BglX; COG1472
511145006476	Glycosyl hydrolase family 3 C-terminal domain; Region: Glyco_hydro_3_C; pfam01915
511145006477	Fibronectin type III-like domain; Region: Fn3-like; pfam14310
511145006478	D-lactate dehydrogenase; Provisional; Region: PRK11183
511145006479	FAD binding domain; Region: FAD_binding_4; cl19922
511145006480	D-lactate dehydrogenase, membrane binding; Region: Lact-deh-memb; pfam09330
511145006481	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
511145006482	D-alanyl-D-alanine endopeptidase; Provisional; Region: pbpG; PRK11669
511145006483	Protein of unknown function (DUF1282); Region: DUF1282; pfam06930
511145006484	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
511145006485	oxidoreductase; Provisional; Region: PRK12743
511145006486	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
511145006487	NAD(P) binding site [chemical binding]; other site
511145006488	active site
511145006489	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
511145006490	Dihydrouridine synthase (Dus); Region: Dus; pfam01207
511145006491	FMN binding site [chemical binding]; other site
511145006492	active site
511145006493	catalytic residues [active]
511145006494	substrate binding site [chemical binding]; other site
511145006495	hypothetical protein; Provisional; Region: PRK01821
511145006496	hypothetical protein; Provisional; Region: PRK10711
511145006497	cytidine deaminase; Provisional; Region: PRK09027
511145006498	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
511145006499	active site
511145006500	catalytic motif [active]
511145006501	Zn binding site [ion binding]; other site
511145006502	Cytidine and deoxycytidylate deaminase zinc-binding region; Region: dCMP_cyt_deam_2; pfam08211
511145006503	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
511145006504	active site
511145006505	catalytic motif [active]
511145006506	Zn binding site [ion binding]; other site
511145006507	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
511145006508	putative active site [active]
511145006509	Protein of unknown function (DUF2542); Region: DUF2542; pfam10808
511145006510	dihydropyrimidine dehydrogenase subunit A; Provisional; Region: PRK11749
511145006511	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
511145006512	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
511145006513	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145006514	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
511145006515	Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain.  DHPD catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines. DHPD contains two FAD, two FMN, and...; Region: DHPD_FMN; cd02940
511145006516	homodimer interface [polypeptide binding]; other site
511145006517	active site
511145006518	FMN binding site [chemical binding]; other site
511145006519	substrate binding site [chemical binding]; other site
511145006520	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145006521	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145006522	TM-ABC transporter signature motif; other site
511145006523	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145006524	galactose/methyl galaxtoside transporter ATP-binding protein; Provisional; Region: PRK10982
511145006525	Walker A/P-loop; other site
511145006526	ATP binding site [chemical binding]; other site
511145006527	Q-loop/lid; other site
511145006528	ABC transporter signature motif; other site
511145006529	Walker B; other site
511145006530	D-loop; other site
511145006531	H-loop/switch region; other site
511145006532	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145006533	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
511145006534	Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species; Region: PBP1_GGBP; cd01539
511145006535	ligand binding site [chemical binding]; other site
511145006536	calcium binding site [ion binding]; other site
511145006537	DNA-binding transcriptional regulator GalS; Provisional; Region: PRK10401
511145006538	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145006539	DNA binding site [nucleotide binding]
511145006540	domain linker motif; other site
511145006541	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
511145006542	dimerization interface (closed form) [polypeptide binding]; other site
511145006543	ligand binding site [chemical binding]; other site
511145006544	Predicted membrane protein [Function unknown]; Region: COG2311
511145006545	hypothetical protein; Provisional; Region: PRK10835
511145006546	GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate.  The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria.  In...; Region: GTP_cyclohydro1; cd00642
511145006547	homodecamer interface [polypeptide binding]; other site
511145006548	active site
511145006549	putative catalytic site residues [active]
511145006550	zinc binding site [ion binding]; other site
511145006551	GTP-CH-I/GFRP interaction surface; other site
511145006552	Predicted esterase [General function prediction only]; Region: COG0627
511145006553	S-formylglutathione hydrolase; Region: PLN02442
511145006554	catecholate siderophore receptor CirA; Provisional; Region: PRK10064
511145006555	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145006556	N-terminal plug; other site
511145006557	ligand-binding site [chemical binding]; other site
511145006558	lysine transporter; Provisional; Region: PRK10836
511145006559	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145006560	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10837
511145006561	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145006562	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
511145006563	putative dimerization interface [polypeptide binding]; other site
511145006564	conserved hypothetical integral membrane protein; Region: TIGR00698
511145006565	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
511145006566	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
511145006567	AP (apurinic/apyrimidinic) site pocket; other site
511145006568	DNA interaction; other site
511145006569	Metal-binding active site; metal-binding site
511145006570	putative kinase; Provisional; Region: PRK09954
511145006571	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
511145006572	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
511145006573	substrate binding site [chemical binding]; other site
511145006574	ATP binding site [chemical binding]; other site
511145006575	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
511145006576	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
511145006577	Nucleoside recognition; Region: Gate; pfam07670
511145006578	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
511145006579	nuc_hydro_IU_UC_XIUA: inosine-uridine preferring, xanthosine-inosine-uridine-adenosine-preferring and, uridine-cytidine preferring nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the...; Region: nuc_hydro_IU_UC_XIUA; cd02651
511145006580	active site
511145006581	tetramer interface [polypeptide binding]; other site
511145006582	DNA-binding transcriptional activator YeiL; Provisional; Region: PRK10402
511145006583	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
511145006584	ligand binding site [chemical binding]; other site
511145006585	flexible hinge region; other site
511145006586	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
511145006587	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
511145006588	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
511145006589	Nucleoside recognition; Region: Gate; pfam07670
511145006590	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
511145006591	Indigoidine synthase A like protein; Region: Indigoidine_A; pfam04227
511145006592	YeiC-like sugar kinase.  Found in eukaryotes and bacteria, YeiC-like kinase is part of the ribokinase/pfkB sugar kinase superfamily. Its oligomerization state is unknown at this time; Region: YeiC_kinase_like; cd01941
511145006593	substrate binding site [chemical binding]; other site
511145006594	ATP binding site [chemical binding]; other site
511145006595	PTS system fructose-specific transporter subunits IIBC; Provisional; Region: PRK10712
511145006596	N-terminal domain of the phosphotransferase system fructose-specific component IIB [Carbohydrate transport and metabolism]; Region: COG3925
511145006597	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145006598	active site
511145006599	P-loop; other site
511145006600	phosphorylation site [posttranslational modification]
511145006601	PTS system, fructose subfamily, IIC component; Region: PTS_IIC_fructo; TIGR01427
511145006602	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
511145006603	putative substrate binding site [chemical binding]; other site
511145006604	putative ATP binding site [chemical binding]; other site
511145006605	bifunctional PTS system fructose-specific transporter subunit IIA/HPr protein; Provisional; Region: PRK11109
511145006606	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145006607	active site
511145006608	phosphorylation site [posttranslational modification]
511145006609	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145006610	dimerization domain swap beta strand [polypeptide binding]; other site
511145006611	regulatory protein interface [polypeptide binding]; other site
511145006612	active site
511145006613	regulatory phosphorylation site [posttranslational modification]; other site
511145006614	sugar efflux transporter B; Provisional; Region: PRK15011
511145006615	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006616	putative substrate translocation pore; other site
511145006617	Putative zinc- or iron-chelating domain; Region: CxxCxxCC; pfam03692
511145006618	elongation factor P; Provisional; Region: PRK04542
511145006619	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
511145006620	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
511145006621	RNA binding site [nucleotide binding]; other site
511145006622	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
511145006623	RNA binding site [nucleotide binding]; other site
511145006624	Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism]; Region: MtlD; COG0246
511145006625	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
511145006626	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
511145006627	Putative GTPases (G3E family) [General function prediction only]; Region: COG0523
511145006628	CobW/HypB/UreG, nucleotide-binding domain; Region: cobW; pfam02492
511145006629	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; smart00833
511145006630	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
511145006631	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cd01610
511145006632	active site
511145006633	outer membrane lipoprotein; Provisional; Region: spr; PRK10838
511145006634	NlpC/P60 family; Region: NLPC_P60; pfam00877
511145006635	phage resistance protein; Provisional; Region: PRK10551
511145006636	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
511145006637	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145006638	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
511145006639	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_14; cd08497
511145006640	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4174
511145006641	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145006642	dimer interface [polypeptide binding]; other site
511145006643	conserved gate region; other site
511145006644	putative PBP binding loops; other site
511145006645	ABC-ATPase subunit interface; other site
511145006646	microcin C ABC transporter permease; Provisional; Region: PRK15021
511145006647	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145006648	dimer interface [polypeptide binding]; other site
511145006649	conserved gate region; other site
511145006650	putative PBP binding loops; other site
511145006651	ABC-ATPase subunit interface; other site
511145006652	microcin C ABC transporter ATP-binding protein YejF; Provisional; Region: PRK15134
511145006653	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145006654	Walker A/P-loop; other site
511145006655	ATP binding site [chemical binding]; other site
511145006656	Q-loop/lid; other site
511145006657	ABC transporter signature motif; other site
511145006658	Walker B; other site
511145006659	D-loop; other site
511145006660	H-loop/switch region; other site
511145006661	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145006662	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145006663	Walker A/P-loop; other site
511145006664	ATP binding site [chemical binding]; other site
511145006665	Q-loop/lid; other site
511145006666	ABC transporter signature motif; other site
511145006667	Walker B; other site
511145006668	D-loop; other site
511145006669	H-loop/switch region; other site
511145006670	hypothetical protein; Provisional; Region: PRK11835
511145006671	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006672	bicyclomycin/multidrug efflux system; Provisional; Region: PRK11102
511145006673	putative substrate translocation pore; other site
511145006674	16S rRNA pseudouridylate synthase A; Provisional; Region: PRK10839
511145006675	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145006676	RNA binding surface [nucleotide binding]; other site
511145006677	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
511145006678	active site
511145006679	uracil binding [chemical binding]; other site
511145006680	DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair]; Region: SSL2; COG1061
511145006681	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145006682	ATP binding site [chemical binding]; other site
511145006683	putative Mg++ binding site [ion binding]; other site
511145006684	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145006685	nucleotide binding region [chemical binding]; other site
511145006686	ATP-binding site [chemical binding]; other site
511145006687	Ribosomal L40e family; Region: Ribosomal_L40e; cl00671
511145006688	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
511145006689	5S rRNA interface [nucleotide binding]; other site
511145006690	CTC domain interface [polypeptide binding]; other site
511145006691	L16 interface [polypeptide binding]; other site
511145006692	nucleoid-associated protein NdpA; Validated; Region: PRK00378
511145006693	hypothetical protein; Provisional; Region: PRK13689
511145006694	Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only]; Region: COG3083
511145006695	Domain of unknown function (DUF3413); Region: DUF3413; pfam11893
511145006696	Sulfatase; Region: Sulfatase; pfam00884
511145006697	Transposase domain (DUF772); Region: DUF772; pfam05598
511145006698	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145006699	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145006700	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145006701	transcriptional regulator NarP; Provisional; Region: PRK10403
511145006702	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006703	active site
511145006704	phosphorylation site [posttranslational modification]
511145006705	intermolecular recognition site; other site
511145006706	dimerization interface [polypeptide binding]; other site
511145006707	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145006708	DNA binding residues [nucleotide binding]
511145006709	dimerization interface [polypeptide binding]; other site
511145006710	Uncharacterized protein involved in biosynthesis of c-type cytochromes [Posttranslational modification, protein turnover, chaperones]; Region: CcmH; COG3088
511145006711	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
511145006712	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145006713	binding surface
511145006714	TPR motif; other site
511145006715	TlpA-like family, DsbE (also known as CcmG and CycY) subfamily; DsbE is a membrane-anchored, periplasmic TRX-like reductase containing a CXXC motif that specifically donates reducing equivalents to apocytochrome c via CcmH, another cytochrome c...; Region: TlpA_like_DsbE; cd03010
511145006716	catalytic residues [active]
511145006717	central insert; other site
511145006718	c-type cytochrome biogenesis protein CcmF; Region: nrfE; TIGR00353
511145006719	cytochrome c-type biogenesis protein CcmE; Reviewed; Region: PRK13150
511145006720	Heme exporter protein D [Intracellular trafficking and secretion]; Region: CcmD; COG3114
511145006721	heme exporter protein CcmC; Region: ccmC; TIGR01191
511145006722	heme exporter protein CcmB; Region: ccmB; TIGR01190
511145006723	cytochrome c biogenesis protein CcmA; Provisional; Region: PRK13538
511145006724	Cytochrome c biogenesis ATP-binding export protein; Region: ABC_CcmA_heme_exporter; cd03231
511145006725	Walker A/P-loop; other site
511145006726	ATP binding site [chemical binding]; other site
511145006727	Q-loop/lid; other site
511145006728	ABC transporter signature motif; other site
511145006729	Walker B; other site
511145006730	D-loop; other site
511145006731	H-loop/switch region; other site
511145006732	cytochrome c-type protein NapC; Provisional; Region: PRK10617
511145006733	cytochrome c nitrate reductase, small subunit; Region: cytochr_NrfH; TIGR03153
511145006734	nitrate reductase cytochrome C550 subunit; Provisional; Region: napB; PRK11586
511145006735	quinol dehydrogenase membrane component; Provisional; Region: napH; PRK09477
511145006736	4Fe-4S binding domain; Region: Fer4_5; pfam12801
511145006737	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145006738	quinol dehydrogenase periplasmic component; Provisional; Region: napG; PRK09476
511145006739	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145006740	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145006741	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145006742	nitrate reductase catalytic subunit; Provisional; Region: PRK13532
511145006743	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_Nitrate-R-NapA-like; cd02754
511145006744	[4Fe-4S] binding site [ion binding]; other site
511145006745	molybdopterin cofactor binding site; other site
511145006746	Nitrate reductases, NapA (Nitrate-R-NapA), NasA, and NarB catalyze the reduction of nitrate to nitrite. Monomeric Nas is located in the cytoplasm and participates in nitrogen assimilation. Dimeric Nap is located in the periplasm and is coupled to quinol...; Region: MopB_CT_Nitrate-R-NapA-like; cd02791
511145006747	molybdopterin cofactor binding site; other site
511145006748	assembly protein for periplasmic nitrate reductase; Provisional; Region: PRK10553
511145006749	ferredoxin-type protein; Provisional; Region: PRK10194
511145006750	ferredoxin-type protein NapF; Region: napF; TIGR00402
511145006751	Protease Inhibitor Ecotin; homodimeric protease inhibitor; Region: Ecotin; cd00242
511145006752	secondary substrate binding site; other site
511145006753	primary substrate binding site; other site
511145006754	inhibition loop; other site
511145006755	dimerization interface [polypeptide binding]; other site
511145006756	malate:quinone oxidoreductase; Validated; Region: PRK05257
511145006757	Predicted dehydrogenase [General function prediction only]; Region: COG0579
511145006758	multidrug transporter membrane component/ATP-binding component; Provisional; Region: PRK10522
511145006759	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
511145006760	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
511145006761	Walker A/P-loop; other site
511145006762	ATP binding site [chemical binding]; other site
511145006763	Q-loop/lid; other site
511145006764	ABC transporter signature motif; other site
511145006765	Walker B; other site
511145006766	D-loop; other site
511145006767	H-loop/switch region; other site
511145006768	alpha-ketoglutarate-dependent dioxygenase AlkB; Provisional; Region: PRK15401
511145006769	bifunctional DNA-binding transcriptional dual regulator/O6-methylguanine-DNA methyltransferase; Provisional; Region: PRK15435
511145006770	Metal binding domain of Ada; Region: Ada_Zn_binding; pfam02805
511145006771	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145006772	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145006773	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
511145006774	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
511145006775	DNA binding site [nucleotide binding]
511145006776	active site
511145006777	thiamine biosynthesis lipoprotein ApbE; Provisional; Region: PRK10461
511145006778	outer membrane porin protein C; Provisional; Region: PRK10554
511145006779	phosphotransfer intermediate protein in two-component regulatory system with RcsBC; Provisional; Region: PRK10618
511145006780	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145006781	ATP binding site [chemical binding]; other site
511145006782	Mg2+ binding site [ion binding]; other site
511145006783	G-X-G motif; other site
511145006784	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145006785	putative binding surface; other site
511145006786	active site
511145006787	transcriptional regulator RcsB; Provisional; Region: PRK10840
511145006788	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006789	active site
511145006790	phosphorylation site [posttranslational modification]
511145006791	intermolecular recognition site; other site
511145006792	dimerization interface [polypeptide binding]; other site
511145006793	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145006794	DNA binding residues [nucleotide binding]
511145006795	dimerization interface [polypeptide binding]; other site
511145006796	hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Provisional; Region: PRK10841
511145006797	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145006798	dimer interface [polypeptide binding]; other site
511145006799	phosphorylation site [posttranslational modification]
511145006800	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145006801	ATP binding site [chemical binding]; other site
511145006802	Mg2+ binding site [ion binding]; other site
511145006803	G-X-G motif; other site
511145006804	RcsC Alpha-Beta-Loop (ABL); Region: RcsC; pfam09456
511145006805	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006806	active site
511145006807	phosphorylation site [posttranslational modification]
511145006808	intermolecular recognition site; other site
511145006809	dimerization interface [polypeptide binding]; other site
511145006810	sensory histidine kinase AtoS; Provisional; Region: PRK11360
511145006811	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145006812	putative active site [active]
511145006813	heme pocket [chemical binding]; other site
511145006814	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145006815	dimer interface [polypeptide binding]; other site
511145006816	phosphorylation site [posttranslational modification]
511145006817	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145006818	ATP binding site [chemical binding]; other site
511145006819	Mg2+ binding site [ion binding]; other site
511145006820	G-X-G motif; other site
511145006821	acetoacetate metabolism regulatory protein AtoC; Provisional; Region: PRK11361
511145006822	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145006823	active site
511145006824	phosphorylation site [posttranslational modification]
511145006825	intermolecular recognition site; other site
511145006826	dimerization interface [polypeptide binding]; other site
511145006827	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145006828	Walker A motif; other site
511145006829	ATP binding site [chemical binding]; other site
511145006830	Walker B motif; other site
511145006831	arginine finger; other site
511145006832	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145006833	acetyl-CoA:acetoacetyl-CoA transferase subunit alpha; Provisional; Region: PRK09920
511145006834	3-oxoacid CoA-transferase, B subunit; Region: pcaJ_scoB_fam; TIGR02428
511145006835	Short chain fatty acid transporter; Region: SCFA_trans; pfam02667
511145006836	putative acyltransferase; Provisional; Region: PRK05790
511145006837	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
511145006838	dimer interface [polypeptide binding]; other site
511145006839	active site
511145006840	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4676
511145006841	Predicted secreted protein [Function unknown]; Region: COG5445
511145006842	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
511145006843	Predicted secreted protein [Function unknown]; Region: COG5445
511145006844	Stage II sporulation protein; Region: SpoIID; pfam08486
511145006845	Predicted secreted protein (DUF2300); Region: DUF2300; pfam10062
511145006846	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3234
511145006847	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4685
511145006848	DNA gyrase subunit A; Validated; Region: PRK05560
511145006849	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
511145006850	CAP-like domain; other site
511145006851	active site
511145006852	primary dimer interface [polypeptide binding]; other site
511145006853	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006854	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006855	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006856	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006857	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006858	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145006859	bifunctional 3-demethylubiquinone-9 3-methyltransferase/ 2-octaprenyl-6-hydroxy phenol methylase; Provisional; Region: PRK05134
511145006860	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145006861	S-adenosylmethionine binding site [chemical binding]; other site
511145006862	adhesin; Provisional; Region: PRK09752
511145006863	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 2, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of the nonprotease autotransporters, Ag43; Region: PL2_Passenger_AT; cd01344
511145006864	Autotransporter beta-domain; Region: Autotransporter; pfam03797
511145006865	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK09103
511145006866	ATP cone domain; Region: ATP-cone; pfam03477
511145006867	Class I ribonucleotide reductase; Region: RNR_I; cd01679
511145006868	active site
511145006869	dimer interface [polypeptide binding]; other site
511145006870	catalytic residues [active]
511145006871	effector binding site; other site
511145006872	R2 peptide binding site; other site
511145006873	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
511145006874	dimer interface [polypeptide binding]; other site
511145006875	putative radical transfer pathway; other site
511145006876	diiron center [ion binding]; other site
511145006877	tyrosyl radical; other site
511145006878	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145006879	catalytic loop [active]
511145006880	iron binding site [ion binding]; other site
511145006881	hypothetical protein; Provisional; Region: PRK09902
511145006882	glycerophosphodiester phosphodiesterase; Provisional; Region: glpQ; PRK11143
511145006883	Glycerophosphodiester phosphodiesterase domain of Escherichia coli (GlpQ) and similar proteins; Region: GDPD_EcGlpQ_like; cd08600
511145006884	active site
511145006885	catalytic site [active]
511145006886	metal binding site [ion binding]; metal-binding site
511145006887	sn-glycerol-3-phosphate transporter; Provisional; Region: glpT; PRK11273
511145006888	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006889	putative substrate translocation pore; other site
511145006890	sn-glycerol-3-phosphate dehydrogenase subunit A; Provisional; Region: glpA; PRK11101
511145006891	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145006892	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; COG3075
511145006893	FAD binding domain; Region: FAD_binding_2; pfam00890
511145006894	glycerol-3-phosphate dehydrogenase, anaerobic, C subunit; Region: glycerol3P_GlpC; TIGR03379
511145006895	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145006896	Cysteine-rich domain; Region: CCG; pfam02754
511145006897	Cysteine-rich domain; Region: CCG; pfam02754
511145006898	hypothetical protein; Provisional; Region: PRK09956
511145006899	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
511145006900	hypothetical protein; Provisional; Region: PRK09956
511145006901	2-keto-3-deoxy-L-rhamnonate aldolase; Provisional; Region: PRK10128
511145006902	4-hydroxyphenylacetate permease; Region: HpaX; TIGR02332
511145006903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145006904	putative substrate translocation pore; other site
511145006905	L-rhamnonate dehydratase; Provisional; Region: PRK15440
511145006906	Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic...; Region: MR_like_2; cd03327
511145006907	putative active site pocket [active]
511145006908	putative metal binding site [ion binding]; other site
511145006909	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145006910	Transcriptional regulator [Transcription]; Region: IclR; COG1414
511145006911	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145006912	hypothetical protein; Provisional; Region: PRK03673
511145006913	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
511145006914	putative MPT binding site; other site
511145006915	Competence-damaged protein; Region: CinA; cl00666
511145006916	YfaZ precursor; Region: YfaZ; pfam07437
511145006917	nucleoside triphosphatase NudI; Provisional; Region: PRK15472
511145006918	Histidine phosphatase domain found in a functionally diverse set of proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP; cd07040
511145006919	catalytic core [active]
511145006920	lipopolysaccharide biosynthesis protein RfbH; Provisional; Region: PRK15407
511145006921	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
511145006922	inhibitor-cofactor binding pocket; inhibition site
511145006923	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145006924	catalytic residue [active]
511145006925	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
511145006926	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
511145006927	Ligand binding site; other site
511145006928	Putative Catalytic site; other site
511145006929	DXD motif; other site
511145006930	bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Validated; Region: PRK08125
511145006931	ArnA, N-terminal formyltransferase domain; Region: FMT_core_ArnA_N; cd08644
511145006932	substrate binding site [chemical binding]; other site
511145006933	cosubstrate binding site; other site
511145006934	catalytic site [active]
511145006935	C-terminal subdomain of the formyltransferase domain on ArnA, which modifies lipid A with 4-amino-4-deoxy-l-arabinose; Region: Arna_FMT_C; cd08702
511145006936	active site
511145006937	hexamer interface [polypeptide binding]; other site
511145006938	Arna decarboxylase_like, extended (e) SDRs; Region: Arna_like_SDR_e; cd05257
511145006939	NAD binding site [chemical binding]; other site
511145006940	substrate binding site [chemical binding]; other site
511145006941	active site
511145006942	4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD; Provisional; Region: PRK15394
511145006943	Catalytic domain of Escherichia coli 4-deoxy-4-formamido-L-arabinose-phosphoundecaprenol deformylase ArnD and other bacterial homologs; Region: CE4_ArnD; cd10939
511145006944	putative active site [active]
511145006945	putative catalytic site [active]
511145006946	putative Zn binding site [ion binding]; other site
511145006947	4-amino-4-deoxy-L-arabinose transferase; Provisional; Region: arnT; PRK13279
511145006948	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane]; Region: ArnT; COG1807
511145006949	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE; Provisional; Region: PRK15051
511145006950	4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnF; Provisional; Region: PRK02971
511145006951	signal transduction protein PmrD; Provisional; Region: PRK15450
511145006952	O-succinylbenzoic acid--CoA ligase; Provisional; Region: PRK09029
511145006953	O-succinylbenzoate-CoA ligase (also known as O-succinylbenzoate-CoA synthase, OSB-CoA synthetase, or MenE); Region: OSB_CoA_lg; cd05912
511145006954	acyl-activating enzyme (AAE) consensus motif; other site
511145006955	putative AMP binding site [chemical binding]; other site
511145006956	putative active site [active]
511145006957	putative CoA binding site [chemical binding]; other site
511145006958	O-succinylbenzoate synthase [Coenzyme metabolism]; Region: MenC; COG1441
511145006959	o-Succinylbenzoate synthase (OSBS) catalyzes the conversion of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) to 4-(2'-carboxyphenyl)-4-oxobutyrate (o-succinylbenzoate or OSB), a reaction in the menaquinone biosynthetic pathway; Region: OSBS; cd03320
511145006960	active site
511145006961	dihydroxynaphthoic acid synthetase; Validated; Region: PRK07396
511145006962	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145006963	substrate binding site [chemical binding]; other site
511145006964	oxyanion hole (OAH) forming residues; other site
511145006965	trimer interface [polypeptide binding]; other site
511145006966	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Provisional; Region: PRK11126
511145006967	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase; Region: menH_SHCHC; TIGR03695
511145006968	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1- carboxylate synthase; Validated; Region: PRK07449
511145006969	Pyrimidine (PYR) binding domain of 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1- carboxylate synthase (MenD) and related proteins; Region: TPP_PYR_MenD; cd07037
511145006970	dimer interface [polypeptide binding]; other site
511145006971	tetramer interface [polypeptide binding]; other site
511145006972	PYR/PP interface [polypeptide binding]; other site
511145006973	TPP binding site [chemical binding]; other site
511145006974	Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key...; Region: TPP_SHCHC_synthase; cd02009
511145006975	TPP-binding site; other site
511145006976	menaquinone-specific isochorismate synthase; Provisional; Region: PRK15012
511145006977	isochorismate synthases; Region: isochor_syn; TIGR00543
511145006978	hypothetical protein; Provisional; Region: PRK10404
511145006979	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145006980	Coenzyme A binding pocket [chemical binding]; other site
511145006981	ribonuclease BN; Region: true_RNase_BN; TIGR02649
511145006982	deubiquitinase; Provisional; Region: PRK11836
511145006983	von Willebrand factor; Region: vWF_A; pfam12450
511145006984	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2304
511145006985	VWA subgroup: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: vWA_subgroup; cd01465
511145006986	metal ion-dependent adhesion site (MIDAS); other site
511145006987	Domain of unknown function (DUF3520); Region: DUF3520; pfam12034
511145006988	Predicted aminopeptidases [General function prediction only]; Region: Iap; COG2234
511145006989	M28 Zn-Peptidases; Region: M28_like_1; cd05640
511145006990	metal binding site [ion binding]; metal-binding site
511145006991	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
511145006992	Tetratricopeptide repeat; Region: TPR_14; pfam13428
511145006993	Tetratricopeptide repeat; Region: TPR_16; pfam13432
511145006994	NADH:ubiquinone oxidoreductase subunit N; Provisional; Region: PRK05777
511145006995	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145006996	NADH:ubiquinone oxidoreductase subunit M; Reviewed; Region: PRK05846
511145006997	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145006998	NADH:ubiquinone oxidoreductase subunit L; Reviewed; Region: PRK06590
511145006999	NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; Region: Oxidored_q1_N; pfam00662
511145007000	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145007001	NADH:ubiquinone oxidoreductase subunit K; Validated; Region: PRK05715
511145007002	NADH:ubiquinone oxidoreductase subunit J; Provisional; Region: PRK06638
511145007003	NADH dehydrogenase subunit I; Provisional; Region: PRK05888
511145007004	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145007005	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
511145007006	NADH:ubiquinone oxidoreductase subunit H; Provisional; Region: PRK06076
511145007007	NADH dehydrogenase subunit G; Validated; Region: PRK08166
511145007008	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145007009	catalytic loop [active]
511145007010	iron binding site [ion binding]; other site
511145007011	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
511145007012	MopB_NDH-1_NuoG2-N7: The second domain of the NuoG subunit (with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex in the respiratory...; Region: MopB_NDH-1_NuoG2-N7; cd02771
511145007013	[4Fe-4S] binding site [ion binding]; other site
511145007014	MopB_CT_NDH-1_NuoG2-N7: C-terminal region of the NuoG-like subunit (of the variant with a [4Fe-4S] cluster, N7) of the NADH-quinone oxidoreductase/NADH dehydrogenase-1 (NDH-1) found in various bacteria. The NDH-1 is the first energy-transducting complex...; Region: MopB_CT_NDH-1_NuoG2-N7; cd02788
511145007015	NADH dehydrogenase I subunit F; Provisional; Region: PRK11278
511145007016	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
511145007017	SLBB domain; Region: SLBB; pfam10531
511145007018	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; pfam10589
511145007019	NADH:ubiquinone oxidoreductase 24 kD subunit [Energy production and conversion]; Region: NuoE; COG1905
511145007020	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
511145007021	putative dimer interface [polypeptide binding]; other site
511145007022	[2Fe-2S] cluster binding site [ion binding]; other site
511145007023	NADH:ubiquinone oxidoreductase 27 kD subunit [Energy production and conversion]; Region: NuoC; COG0852
511145007024	bifunctional NADH:ubiquinone oxidoreductase subunit C/D; Provisional; Region: PRK11742
511145007025	NADH dehydrogenase I, D subunit; Region: NuoD; TIGR01962
511145007026	NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases [Energy production and conversion]; Region: NuoB; COG0377
511145007027	NADH:ubiquinone oxidoreductase subunit A; Validated; Region: PRK06602
511145007028	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
511145007029	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145007030	The C-terminal substrate domain of LysR-like regulator LrhA (LysR homologue A) and that of closely related homologs, contains the type 2 periplasmic binding fold; Region: PBP2_LrhA_like; cd08439
511145007031	putative dimerization interface [polypeptide binding]; other site
511145007032	aminotransferase AlaT; Validated; Region: PRK09265
511145007033	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145007034	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145007035	homodimer interface [polypeptide binding]; other site
511145007036	catalytic residue [active]
511145007037	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145007038	Zn2+ binding site [ion binding]; other site
511145007039	Mg2+ binding site [ion binding]; other site
511145007040	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
511145007041	transmembrane helices; other site
511145007042	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
511145007043	TrkA-C domain; Region: TrkA_C; pfam02080
511145007044	TrkA-C domain; Region: TrkA_C; pfam02080
511145007045	Permease SLC13 (solute carrier 13).  The sodium/dicarboxylate cotransporter NaDC-1 has been shown to translocate Krebs cycle intermediates such as succinate, citrate, and alpha-ketoglutarate across plasma membranes rabbit, human, and rat kidney. It is...; Region: SLC13_permease; cd01115
511145007046	putative phosphatase; Provisional; Region: PRK11587
511145007047	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145007048	active site
511145007049	motif I; other site
511145007050	motif II; other site
511145007051	hypothetical protein; Validated; Region: PRK05445
511145007052	hypothetical protein; Provisional; Region: PRK01816
511145007053	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
511145007054	phosphate acetyltransferase; Reviewed; Region: PRK05632
511145007055	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
511145007056	DRTGG domain; Region: DRTGG; pfam07085
511145007057	phosphate acetyltransferase; Region: pta; TIGR00651
511145007058	hypothetical protein; Provisional; Region: PRK11588
511145007059	Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly...; Region: Nudix_Hydrolase_38; cd04697
511145007060	nudix motif; other site
511145007061	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
511145007062	active site
511145007063	metal binding site [ion binding]; metal-binding site
511145007064	homotetramer interface [polypeptide binding]; other site
511145007065	glutathione S-transferase; Provisional; Region: PRK15113
511145007066	Glutathione S-transferase (GST) family, N-terminal domain; a large, diverse group of cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of  glutathione (GSH) with a wide range of endogenous and xenobiotic...; Region: GST_N_family; cd00570
511145007067	C-terminal domain interface [polypeptide binding]; other site
511145007068	GSH binding site (G-site) [chemical binding]; other site
511145007069	dimer interface [polypeptide binding]; other site
511145007070	C-terminal, alpha helical domain of an unknown subfamily 4 of Glutathione S-transferases; Region: GST_C_4; cd03195
511145007071	N-terminal domain interface [polypeptide binding]; other site
511145007072	putative dimer interface [polypeptide binding]; other site
511145007073	putative substrate binding pocket (H-site) [chemical binding]; other site
511145007074	GSH-dependent disulfide bond oxidoreductase; Provisional; Region: PRK13972
511145007075	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
511145007076	C-terminal domain interface [polypeptide binding]; other site
511145007077	GSH binding site (G-site) [chemical binding]; other site
511145007078	dimer interface [polypeptide binding]; other site
511145007079	C-terminal, alpha helical domain of Escherichia coli YfcG Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YfcG_like; cd10291
511145007080	N-terminal domain interface [polypeptide binding]; other site
511145007081	putative dimer interface [polypeptide binding]; other site
511145007082	active site
511145007083	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
511145007084	homooctamer interface [polypeptide binding]; other site
511145007085	active site
511145007086	atypical (a) SDRs, subgroup 8; Region: SDR_a8; cd05242
511145007087	Predicted nucleoside-diphosphate sugar epimerase [General function prediction only]; Region: COG1090
511145007088	putative NAD(P) binding site [chemical binding]; other site
511145007089	putative active site [active]
511145007090	hypothetical protein; Provisional; Region: PRK09956
511145007091	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
511145007092	histidine/lysine/arginine/ornithine transporter subunit; Provisional; Region: PRK10619
511145007093	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
511145007094	Walker A/P-loop; other site
511145007095	ATP binding site [chemical binding]; other site
511145007096	Q-loop/lid; other site
511145007097	ABC transporter signature motif; other site
511145007098	Walker B; other site
511145007099	D-loop; other site
511145007100	H-loop/switch region; other site
511145007101	ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160
511145007102	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145007103	dimer interface [polypeptide binding]; other site
511145007104	conserved gate region; other site
511145007105	putative PBP binding loops; other site
511145007106	ABC-ATPase subunit interface; other site
511145007107	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
511145007108	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145007109	dimer interface [polypeptide binding]; other site
511145007110	conserved gate region; other site
511145007111	putative PBP binding loops; other site
511145007112	ABC-ATPase subunit interface; other site
511145007113	histidine ABC transporter substrate-binding protein HisJ; Provisional; Region: PRK15437
511145007114	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145007115	substrate binding pocket [chemical binding]; other site
511145007116	membrane-bound complex binding site; other site
511145007117	hinge residues; other site
511145007118	ABC transporter lysine/arginine/ornithine binding periplasmic protein; Provisional; Region: PRK15010
511145007119	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145007120	substrate binding pocket [chemical binding]; other site
511145007121	membrane-bound complex binding site; other site
511145007122	hinge residues; other site
511145007123	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Provisional; Region: PRK06029
511145007124	amidophosphoribosyltransferase; Provisional; Region: PRK09246
511145007125	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
511145007126	active site
511145007127	tetramer interface [polypeptide binding]; other site
511145007128	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145007129	active site
511145007130	colicin V production protein; Provisional; Region: PRK10845
511145007131	cell division protein DedD; Provisional; Region: PRK11633
511145007132	Sporulation related domain; Region: SPOR; pfam05036
511145007133	bifunctional folylpolyglutamate synthase/ dihydrofolate synthase; Provisional; Region: PRK10846
511145007134	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145007135	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145007136	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
511145007137	hypothetical protein; Provisional; Region: PRK10847
511145007138	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
511145007139	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
511145007140	dimerization interface 3.5A [polypeptide binding]; other site
511145007141	active site
511145007142	putative semialdehyde dehydrogenase; Provisional; Region: PRK08040
511145007143	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
511145007144	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
511145007145	erythronate-4-phosphate dehydrogenase PdxB; Provisional; Region: PRK15438
511145007146	D-Erythronate-4-Phosphate Dehydrogenase NAD-binding and catalytic domains; Region: ErythrP_dh; cd12158
511145007147	ligand binding site [chemical binding]; other site
511145007148	NAD binding site [chemical binding]; other site
511145007149	catalytic site [active]
511145007150	homodimer interface [polypeptide binding]; other site
511145007151	flagella biosynthesis regulator; Provisional; Region: flk; PRK10715
511145007152	putative transporter; Provisional; Region: PRK12382
511145007153	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145007154	putative substrate translocation pore; other site
511145007155	3-oxoacyl-(acyl carrier protein) synthase I; Reviewed; Region: PRK07967
511145007156	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
511145007157	dimer interface [polypeptide binding]; other site
511145007158	active site
511145007159	Uncharacterized conserved protein [Function unknown]; Region: COG4121
511145007160	bifunctional tRNA (mnm(5)s(2)U34)-methyltransferase/FAD-dependent cmnm(5)s(2)U34 oxidoreductase; Reviewed; Region: mnmC; PRK01747
511145007161	tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain; Region: MnmC_Cterm; TIGR03197
511145007162	YfcL protein; Region: YfcL; pfam08891
511145007163	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3101
511145007164	hypothetical protein; Provisional; Region: PRK10621
511145007165	Murein endopeptidase [Cell envelope biogenesis, outer membrane]; Region: MepA; COG3770
511145007166	penicillin-insensitive murein endopeptidase; Reviewed; Region: mepA; PRK09429
511145007167	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
511145007168	Tetramer interface [polypeptide binding]; other site
511145007169	active site
511145007170	FMN-binding site [chemical binding]; other site
511145007171	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK11805
511145007172	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145007173	S-adenosylmethionine binding site [chemical binding]; other site
511145007174	hypothetical protein; Provisional; Region: PRK04946
511145007175	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2840
511145007176	Protein of unknown function (DUF2544); Region: DUF2544; pfam11245
511145007177	Fimbrial protein; Region: Fimbrial; cl01416
511145007178	Fimbrial protein; Region: Fimbrial; cl01416
511145007179	Fimbrial protein; Region: Fimbrial; cl01416
511145007180	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145007181	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145007182	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145007183	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
511145007184	catalytic core [active]
511145007185	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadJ; PRK11154
511145007186	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145007187	substrate binding site [chemical binding]; other site
511145007188	oxyanion hole (OAH) forming residues; other site
511145007189	trimer interface [polypeptide binding]; other site
511145007190	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
511145007191	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145007192	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145007193	3-ketoacyl-CoA thiolase; Reviewed; Region: fadI; PRK08963
511145007194	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
511145007195	dimer interface [polypeptide binding]; other site
511145007196	active site
511145007197	conserved hypothetical protein; Region: TIGR00743
511145007198	long-chain fatty acid outer membrane transporter; Provisional; Region: PRK10716
511145007199	ABC transporter outer membrane lipoprotein; Provisional; Region: PRK15091
511145007200	Formate/nitrite family of transporters [Inorganic ion transport and metabolism]; Region: FocA; COG2116
511145007201	cryptic prophage CPS-53
511145007202	integrase; Provisional; Region: PRK09692
511145007203	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
511145007204	active site
511145007205	Int/Topo IB signature motif; other site
511145007206	Predicted membrane protein [Function unknown]; Region: COG2246
511145007207	undecaprenyl phosphate 4-deoxy-4-formamido-L-arabinose transferase; Provisional; Region: PRK10714
511145007208	Bacterial DPM1_like enzymes are related to eukaryotic DPM1; Region: DPM1_like_bac; cd04187
511145007209	Ligand binding site; other site
511145007210	Putative Catalytic site; other site
511145007211	DXD motif; other site
511145007212	Caudovirales tail fibre assembly protein; Region: Caudo_TAP; pfam02413
511145007213	PerC transcriptional activator; Region: PerC; pfam06069
511145007214	Uncharacterized conserved protein [Function unknown]; Region: COG5532
511145007215	Predicted hydrolases of HD superfamily [General function prediction only]; Region: COG1896
511145007216	Protein of unknown function (DUF551); Region: DUF551; pfam04448
511145007217	Prophage CP4-57 regulatory protein (AlpA); Region: Phage_AlpA; cl17523
511145007218	DNA-binding transcriptional regulator DsdC; Provisional; Region: PRK10086
511145007219	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145007220	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
511145007221	dimerization interface [polypeptide binding]; other site
511145007222	substrate binding pocket [chemical binding]; other site
511145007223	permease DsdX; Provisional; Region: PRK09921
511145007224	GntP family permease; Region: GntP_permease; pfam02447
511145007225	D-Serine dehydratase is a pyridoxal phosphate (PLP)-dependent enzyme which catalyzes the conversion of L- or D-serine  to pyruvate and ammonia.  D-serine dehydratase serves as a detoxifying enzyme in most E. coli strains where D-serine is a competitive...; Region: D-Ser-dehyd; cd06447
511145007226	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145007227	catalytic residue [active]
511145007228	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
511145007229	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145007230	putative substrate translocation pore; other site
511145007231	efflux pump membrane protein (multidrug resistance protein A); Region: 8a0101; TIGR00998
511145007232	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145007233	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145007234	DNA-binding transcriptional activator EvgA; Provisional; Region: PRK09958
511145007235	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145007236	active site
511145007237	phosphorylation site [posttranslational modification]
511145007238	intermolecular recognition site; other site
511145007239	dimerization interface [polypeptide binding]; other site
511145007240	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145007241	DNA binding residues [nucleotide binding]
511145007242	dimerization interface [polypeptide binding]; other site
511145007243	hybrid sensory histidine kinase in two-component regulatory system with EvgA; Provisional; Region: PRK09959
511145007244	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145007245	substrate binding pocket [chemical binding]; other site
511145007246	membrane-bound complex binding site; other site
511145007247	hinge residues; other site
511145007248	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145007249	substrate binding pocket [chemical binding]; other site
511145007250	membrane-bound complex binding site; other site
511145007251	hinge residues; other site
511145007252	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145007253	dimer interface [polypeptide binding]; other site
511145007254	phosphorylation site [posttranslational modification]
511145007255	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145007256	ATP binding site [chemical binding]; other site
511145007257	Mg2+ binding site [ion binding]; other site
511145007258	G-X-G motif; other site
511145007259	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145007260	active site
511145007261	phosphorylation site [posttranslational modification]
511145007262	intermolecular recognition site; other site
511145007263	dimerization interface [polypeptide binding]; other site
511145007264	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145007265	putative binding surface; other site
511145007266	active site
511145007267	putative CoA-transferase; Provisional; Region: PRK11430
511145007268	putative transporter YfdV; Provisional; Region: PRK09903
511145007269	oxalyl-CoA decarboxylase; Region: oxalate_oxc; TIGR03254
511145007270	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
511145007271	PYR/PP interface [polypeptide binding]; other site
511145007272	dimer interface [polypeptide binding]; other site
511145007273	TPP binding site [chemical binding]; other site
511145007274	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
511145007275	Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL...; Region: TPP_BZL_OCoD_HPCL; cd02004
511145007276	TPP-binding site; other site
511145007277	dimer interface [polypeptide binding]; other site
511145007278	formyl-coenzyme A transferase; Provisional; Region: PRK05398
511145007279	hypothetical protein; Provisional; Region: PRK10316
511145007280	YfdX protein; Region: YfdX; pfam10938
511145007281	Protein of unknown function (DUF2545); Region: DUF2545; pfam10810
511145007282	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
511145007283	putative acyl-acceptor binding pocket; other site
511145007284	aminotransferase; Validated; Region: PRK08175
511145007285	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145007286	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145007287	homodimer interface [polypeptide binding]; other site
511145007288	catalytic residue [active]
511145007289	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
511145007290	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
511145007291	GAF domain; Region: GAF; pfam01590
511145007292	Histidine kinase; Region: His_kinase; pfam06580
511145007293	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145007294	ATP binding site [chemical binding]; other site
511145007295	Mg2+ binding site [ion binding]; other site
511145007296	G-X-G motif; other site
511145007297	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
511145007298	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145007299	active site
511145007300	phosphorylation site [posttranslational modification]
511145007301	intermolecular recognition site; other site
511145007302	dimerization interface [polypeptide binding]; other site
511145007303	LytTr DNA-binding domain; Region: LytTR; pfam04397
511145007304	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145007305	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145007306	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145007307	dimerization domain swap beta strand [polypeptide binding]; other site
511145007308	regulatory protein interface [polypeptide binding]; other site
511145007309	active site
511145007310	regulatory phosphorylation site [posttranslational modification]; other site
511145007311	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
511145007312	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
511145007313	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145007314	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
511145007315	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145007316	active site
511145007317	phosphorylation site [posttranslational modification]
511145007318	M42 Peptidases, also known as glutamyl aminopeptidase family; Region: M42; cd05638
511145007319	oligomer interface [polypeptide binding]; other site
511145007320	active site
511145007321	metal binding site [ion binding]; metal-binding site
511145007322	aminopeptidase; Provisional; Region: PRK09795
511145007323	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
511145007324	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
511145007325	active site
511145007326	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
511145007327	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145007328	active site
511145007329	P-loop; other site
511145007330	phosphorylation site [posttranslational modification]
511145007331	glucokinase; Provisional; Region: glk; PRK00292
511145007332	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145007333	nucleotide binding site [chemical binding]; other site
511145007334	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cd00400
511145007335	Cl- selectivity filter; other site
511145007336	Cl- binding residues [ion binding]; other site
511145007337	pore gating glutamate residue; other site
511145007338	dimer interface [polypeptide binding]; other site
511145007339	Protein of unknown function (DUF2502); Region: DUF2502; pfam10697
511145007340	manganese transport protein MntH; Reviewed; Region: PRK00701
511145007341	Natural resistance-associated macrophage protein; Region: Nramp; pfam01566
511145007342	Nucleoside permease [Nucleotide transport and metabolism]; Region: NupC; COG1972
511145007343	Na+ dependent nucleoside transporter N-terminus; Region: Nucleos_tra2_N; pfam01773
511145007344	Nucleoside recognition; Region: Gate; pfam07670
511145007345	Na+ dependent nucleoside transporter C-terminus; Region: Nucleos_tra2_C; pfam07662
511145007346	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
511145007347	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145007348	MASE1; Region: MASE1; pfam05231
511145007349	diguanylate cyclase; Region: GGDEF; smart00267
511145007350	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145007351	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
511145007352	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145007353	salt bridge; other site
511145007354	non-specific DNA binding site [nucleotide binding]; other site
511145007355	Putative transcription regulator (DUF1323); Region: DUF1323; pfam07037
511145007356	sequence-specific DNA binding site [nucleotide binding]; other site
511145007357	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
511145007358	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
511145007359	active site
511145007360	HIGH motif; other site
511145007361	KMSKS motif; other site
511145007362	Protein of unknown function (DUF3150); Region: DUF3150; pfam11348
511145007363	DNA-binding transcriptional activator XapR; Provisional; Region: PRK09986
511145007364	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145007365	The C-terminal substrate binding domain of LysR-type transcriptional regulator XapR involved in xanthosine catabolism, contains the type 2 periplasmic binding fold; Region: PBP2_XapR; cd08449
511145007366	putative dimerization interface [polypeptide binding]; other site
511145007367	putative substrate binding pocket [chemical binding]; other site
511145007368	nucleoside transporter; Region: 2A0110; TIGR00889
511145007369	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
511145007370	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
511145007371	purine nucleoside phosphorylase; Provisional; Region: PRK08202
511145007372	hypothetical protein; Provisional; Region: PRK11528
511145007373	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145007374	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145007375	TThe C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold; Region: PBP2_LTTR_like_4; cd08440
511145007376	putative dimerization interface [polypeptide binding]; other site
511145007377	SBF-like CPA transporter family (DUF4137); Region: DUF4137; pfam13593
511145007378	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3530
511145007379	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
511145007380	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
511145007381	nucleotide binding pocket [chemical binding]; other site
511145007382	K-X-D-G motif; other site
511145007383	catalytic site [active]
511145007384	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
511145007385	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
511145007386	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
511145007387	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
511145007388	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
511145007389	Dimer interface [polypeptide binding]; other site
511145007390	BRCT sequence motif; other site
511145007391	cell division protein ZipA; Provisional; Region: PRK03427
511145007392	hypothetical protein; Provisional; Region: PHA03160
511145007393	ZipA C-terminal domain. ZipA, a membrane-anchored protein, is one of at least nine essential gene products necessary for assembly of the septal ring which mediates cell division in E.coli. ZipA and FtsA directly bind FtsZ, a homolog of eukaryotic...; Region: ZipA; cd00231
511145007394	FtsZ protein binding site [polypeptide binding]; other site
511145007395	putative sulfate transport protein CysZ; Validated; Region: PRK04949
511145007396	cysteine synthase; Region: PLN02565
511145007397	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
511145007398	dimer interface [polypeptide binding]; other site
511145007399	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145007400	catalytic residue [active]
511145007401	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145007402	dimerization domain swap beta strand [polypeptide binding]; other site
511145007403	regulatory protein interface [polypeptide binding]; other site
511145007404	active site
511145007405	regulatory phosphorylation site [posttranslational modification]; other site
511145007406	phosphoenolpyruvate-protein phosphotransferase; Provisional; Region: PRK11177
511145007407	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
511145007408	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145007409	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
511145007410	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
511145007411	HPr interaction site; other site
511145007412	glycerol kinase (GK) interaction site [polypeptide binding]; other site
511145007413	active site
511145007414	phosphorylation site [posttranslational modification]
511145007415	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
511145007416	dimer interface [polypeptide binding]; other site
511145007417	pyridoxal binding site [chemical binding]; other site
511145007418	ATP binding site [chemical binding]; other site
511145007419	hypothetical protein; Provisional; Region: PRK10318
511145007420	WGR domain of molybdate metabolism regulator and related proteins; Region: WGR_MMR_like; cd07996
511145007421	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4884
511145007422	cysteine synthase; Region: PLN02565
511145007423	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
511145007424	dimer interface [polypeptide binding]; other site
511145007425	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145007426	catalytic residue [active]
511145007427	sulfate/thiosulfate transporter subunit; Provisional; Region: PRK10851
511145007428	ATP-binding cassette domain of the sulfate transporter; Region: ABC_CysA_sulfate_importer; cd03296
511145007429	Walker A/P-loop; other site
511145007430	ATP binding site [chemical binding]; other site
511145007431	Q-loop/lid; other site
511145007432	ABC transporter signature motif; other site
511145007433	Walker B; other site
511145007434	D-loop; other site
511145007435	H-loop/switch region; other site
511145007436	TOBE-like domain; Region: TOBE_3; pfam12857
511145007437	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
511145007438	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145007439	dimer interface [polypeptide binding]; other site
511145007440	conserved gate region; other site
511145007441	putative PBP binding loops; other site
511145007442	ABC-ATPase subunit interface; other site
511145007443	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
511145007444	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145007445	dimer interface [polypeptide binding]; other site
511145007446	conserved gate region; other site
511145007447	putative PBP binding loops; other site
511145007448	ABC-ATPase subunit interface; other site
511145007449	thiosulfate transporter subunit; Provisional; Region: PRK10852
511145007450	short chain dehydrogenase; Provisional; Region: PRK08226
511145007451	human DHRS6-like, classical (c) SDRs; Region: DHRS6_like_SDR_c; cd05368
511145007452	NAD binding site [chemical binding]; other site
511145007453	homotetramer interface [polypeptide binding]; other site
511145007454	homodimer interface [polypeptide binding]; other site
511145007455	active site
511145007456	transcriptional regulator MurR; Provisional; Region: PRK15482
511145007457	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
511145007458	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
511145007459	putative active site [active]
511145007460	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
511145007461	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
511145007462	putative active site [active]
511145007463	PTS system N-acetylmuramic acid transporter subunits EIIBC; Reviewed; Region: murP; PRK09586
511145007464	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145007465	active site turn [active]
511145007466	phosphorylation site [posttranslational modification]
511145007467	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
511145007468	putative periplasmic esterase; Provisional; Region: PRK03642
511145007469	Dyp-type peroxidase family; Region: Dyp_perox; pfam04261
511145007470	RpoE-regulated lipoprotein; Provisional; Region: PRK10718
511145007471	Protein of unknown function (DUF2919); Region: DUF2919; pfam11143
511145007472	putative acetyltransferase; Provisional; Region: PRK03624
511145007473	Uncharacterized conserved protein [Function unknown]; Region: COG3375
511145007474	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145007475	Coenzyme A binding pocket [chemical binding]; other site
511145007476	N-acetylmuramoyl-l-alanine amidase I; Provisional; Region: PRK10319
511145007477	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
511145007478	active site
511145007479	metal binding site [ion binding]; metal-binding site
511145007480	coproporphyrinogen III oxidase; Provisional; Region: PRK05330
511145007481	transcriptional regulator EutR; Provisional; Region: PRK10130
511145007482	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145007483	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145007484	carboxysome structural protein EutK; Provisional; Region: PRK15466
511145007485	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
511145007486	Hexamer interface [polypeptide binding]; other site
511145007487	Hexagonal pore residue; other site
511145007488	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
511145007489	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
511145007490	putative hexamer interface [polypeptide binding]; other site
511145007491	putative hexagonal pore; other site
511145007492	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
511145007493	putative hexamer interface [polypeptide binding]; other site
511145007494	putative hexagonal pore; other site
511145007495	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
511145007496	Ethanolamine ammonia-lyase, large subunit [Amino acid transport and metabolism]; Region: EutB; COG4303
511145007497	cryptic prophage Eut/CPZ-55
511145007498	integrase; Provisional; Region: PRK09692
511145007499	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
511145007500	active site
511145007501	Int/Topo IB signature motif; other site
511145007502	Helix-turn-helix domain of Hin and related proteins; Region: HTH_Hin_like; cl17393
511145007503	Ethanolamine utilization protein, possible chaperonin protecting lyase from inhibition [Amino acid transport and metabolism]; Region: EutA; COG4819
511145007504	Ethanolamine utilization protein [Amino acid transport and metabolism]; Region: EutH; COG3192
511145007505	iron-containing alcohol dehydrogenases (Fe-ADH)-like; Region: Fe-ADH; cd08551
511145007506	active site
511145007507	metal binding site [ion binding]; metal-binding site
511145007508	Ethanolamine utilization protein, possible chaperonin [Amino acid transport and metabolism]; Region: EutJ; COG4820
511145007509	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145007510	nucleotide binding site [chemical binding]; other site
511145007511	nucleotide binding site [chemical binding]; other site
511145007512	Cell division protein FtsA; Region: FtsA; cl17206
511145007513	Ethanolamine utilization protein EutE-like; Region: ALDH_EutE; cd07121
511145007514	putative catalytic cysteine [active]
511145007515	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
511145007516	Hexamer/Pentamer interface [polypeptide binding]; other site
511145007517	central pore; other site
511145007518	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
511145007519	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
511145007520	Hexamer interface [polypeptide binding]; other site
511145007521	Hexagonal pore residue; other site
511145007522	phosphotransacetylase; Reviewed; Region: eutD; PRK09653
511145007523	ethanolamine utilization cobalamin adenosyltransferase; Provisional; Region: PRK15020
511145007524	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
511145007525	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
511145007526	G1 box; other site
511145007527	GTP/Mg2+ binding site [chemical binding]; other site
511145007528	G2 box; other site
511145007529	Switch I region; other site
511145007530	G3 box; other site
511145007531	Switch II region; other site
511145007532	G4 box; other site
511145007533	G5 box; other site
511145007534	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
511145007535	putative hexamer interface [polypeptide binding]; other site
511145007536	putative hexagonal pore; other site
511145007537	bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed; Region: PRK07232
511145007538	Malic enzyme, N-terminal domain; Region: malic; pfam00390
511145007539	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
511145007540	putative NAD(P) binding site [chemical binding]; other site
511145007541	Phosphotransacetylase [Energy production and conversion]; Region: Pta; COG0280
511145007542	transaldolase-like protein; Provisional; Region: PTZ00411
511145007543	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
511145007544	active site
511145007545	dimer interface [polypeptide binding]; other site
511145007546	catalytic residue [active]
511145007547	transketolase; Reviewed; Region: PRK12753
511145007548	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
511145007549	TPP-binding site [chemical binding]; other site
511145007550	dimer interface [polypeptide binding]; other site
511145007551	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
511145007552	PYR/PP interface [polypeptide binding]; other site
511145007553	dimer interface [polypeptide binding]; other site
511145007554	TPP binding site [chemical binding]; other site
511145007555	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
511145007556	Protein of unknown function (DUF1176); Region: DUF1176; pfam06674
511145007557	nudix-type nucleoside diphosphatase, YffH/AdpP family; Region: TIGR00052
511145007558	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
511145007559	dimer interface [polypeptide binding]; other site
511145007560	ADP-ribose binding site [chemical binding]; other site
511145007561	active site
511145007562	nudix motif; other site
511145007563	metal binding site [ion binding]; metal-binding site
511145007564	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12769
511145007565	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145007566	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
511145007567	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145007568	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145007569	nitrate/nitrite sensor protein NarQ; Provisional; Region: PRK10935
511145007570	Type IV pili methyl-accepting chemotaxis transducer N-term; Region: PilJ; pfam13675
511145007571	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145007572	dimerization interface [polypeptide binding]; other site
511145007573	Histidine kinase; Region: HisKA_3; pfam07730
511145007574	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145007575	ATP binding site [chemical binding]; other site
511145007576	Mg2+ binding site [ion binding]; other site
511145007577	G-X-G motif; other site
511145007578	aminoglycoside/multidrug efflux system; Provisional; Region: PRK10555
511145007579	MMPL family; Region: MMPL; cl14618
511145007580	MMPL family; Region: MMPL; cl14618
511145007581	Arsenate Reductase (ArsC) family, Yffb subfamily; Yffb is an uncharacterized bacterial protein encoded by the yffb gene, related to the thioredoxin-fold arsenic reductases, ArsC. The structure of Yffb and the conservation of the catalytic cysteine...; Region: ArsC_Yffb; cd03035
511145007582	putative catalytic residues [active]
511145007583	succinyl-diaminopimelate desuccinylase; Reviewed; Region: PRK13009
511145007584	M20 Peptidase proteobacterial DapE encoded N-succinyl-L,L-diaminopimelic acid desuccinylase; Region: M20_DapE_proteobac; cd03891
511145007585	metal binding site [ion binding]; metal-binding site
511145007586	dimer interface [polypeptide binding]; other site
511145007587	hypothetical protein; Provisional; Region: PRK13664
511145007588	putative hydrolase; Provisional; Region: PRK11460
511145007589	Predicted esterase [General function prediction only]; Region: COG0400
511145007590	Predicted P-loop ATPase fused to an acetyltransferase [General function prediction only]; Region: COG1444
511145007591	Domain of unknown function (DUF1726); Region: DUF1726; pfam08351
511145007592	Helicase; Region: Helicase_RecD; pfam05127
511145007593	GNAT acetyltransferase 2; Region: GNAT_acetyltr_2; pfam13718
511145007594	Possible tRNA binding domain; Region: tRNA_bind_2; pfam13725
511145007595	Putative neutral zinc metallopeptidase; Region: Zn_peptidase; pfam04228
511145007596	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
511145007597	ATP binding site [chemical binding]; other site
511145007598	active site
511145007599	substrate binding site [chemical binding]; other site
511145007600	lipoprotein; Provisional; Region: PRK11679
511145007601	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
511145007602	dimer interface [polypeptide binding]; other site
511145007603	active site
511145007604	catalytic residue [active]
511145007605	glycine cleavage system transcriptional repressor; Provisional; Region: gcvR; PRK11589
511145007606	ACT domains that comprise the Glycine Cleavage System Transcriptional Repressor (GcvR) protein, and other related domains; Region: ACT_GcvR_1; cd04893
511145007607	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
511145007608	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
511145007609	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
511145007610	catalytic triad [active]
511145007611	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
511145007612	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145007613	hydrogenase 4 subunit B; Validated; Region: PRK06521
511145007614	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145007615	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
511145007616	hydrogenase 4 subunit D; Validated; Region: PRK06525
511145007617	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145007618	hydrogenase 4 membrane subunit; Provisional; Region: hyfE; PRK11492
511145007619	hydrogenase 4 subunit F; Validated; Region: PRK06458
511145007620	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145007621	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
511145007622	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
511145007623	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
511145007624	hydrogenase 4 subunit H; Validated; Region: PRK08222
511145007625	4Fe-4S binding domain; Region: Fer4; pfam00037
511145007626	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
511145007627	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
511145007628	Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains [Transcription / Signal transduction mechanisms]; Region: FhlA; COG3604
511145007629	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145007630	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145007631	Walker A motif; other site
511145007632	ATP binding site [chemical binding]; other site
511145007633	Walker B motif; other site
511145007634	arginine finger; other site
511145007635	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145007636	putative formate transporter; Provisional; Region: focB; PRK09713
511145007637	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
511145007638	Putative Zn-dependent protease, contains TPR repeats [General function prediction only]; Region: COG4783
511145007639	Peptidase family M48; Region: Peptidase_M48; cl12018
511145007640	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
511145007641	catalytic residues [active]
511145007642	DNA replication initiation factor; Provisional; Region: PRK08084
511145007643	ATPase involved in DNA replication initiation [DNA replication, recombination, and repair]; Region: DnaA; COG0593
511145007644	uracil transporter; Provisional; Region: PRK10720
511145007645	uracil-xanthine permease; Region: ncs2; TIGR00801
511145007646	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145007647	active site
511145007648	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
511145007649	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
511145007650	dimerization interface [polypeptide binding]; other site
511145007651	putative ATP binding site [chemical binding]; other site
511145007652	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
511145007653	active site
511145007654	substrate binding site [chemical binding]; other site
511145007655	cosubstrate binding site; other site
511145007656	catalytic site [active]
511145007657	Polyphosphate kinase [Inorganic ion transport and metabolism]; Region: Ppk; COG0855
511145007658	Polyphosphate kinase N-terminal domain; Region: PP_kinase_N; pfam13089
511145007659	Polyphosphate kinase middle domain; Region: PP_kinase; pfam02503
511145007660	Catalytic C-terminal domain, first repeat, of prokaryotic polyphosphate kinase 1 and similar proteins; Region: PLDc_PPK1_C1; cd09114
511145007661	domain interface [polypeptide binding]; other site
511145007662	active site
511145007663	catalytic site [active]
511145007664	Catalytic C-terminal domain, second repeat, of Escherichia coli polyphosphate kinase 1 and similar proteins; Region: PLDc_EcPPK1_C2_like; cd09167
511145007665	domain interface [polypeptide binding]; other site
511145007666	active site
511145007667	catalytic site [active]
511145007668	exopolyphosphatase; Provisional; Region: PRK10854
511145007669	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
511145007670	MASE1; Region: MASE1; pfam05231
511145007671	diguanylate cyclase; Region: GGDEF; smart00267
511145007672	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145007673	Protein of unknown function (DUF2633); Region: DUF2633; pfam11119
511145007674	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
511145007675	GMP synthase; Reviewed; Region: guaA; PRK00074
511145007676	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
511145007677	AMP/PPi binding site [chemical binding]; other site
511145007678	candidate oxyanion hole; other site
511145007679	catalytic triad [active]
511145007680	potential glutamine specificity residues [chemical binding]; other site
511145007681	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
511145007682	ATP Binding subdomain [chemical binding]; other site
511145007683	Ligand Binding sites [chemical binding]; other site
511145007684	Dimerization subdomain; other site
511145007685	inosine 5'-monophosphate dehydrogenase; Reviewed; Region: PRK05567
511145007686	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
511145007687	active site
511145007688	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH; cd04601
511145007689	exodeoxyribonuclease VII, large subunit; Region: xseA; TIGR00237
511145007690	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
511145007691	generic binding surface II; other site
511145007692	generic binding surface I; other site
511145007693	zinc-ribbons; Region: zinc-ribbons_6; pfam07191
511145007694	GTP-binding protein Der; Reviewed; Region: PRK00093
511145007695	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
511145007696	G1 box; other site
511145007697	GTP/Mg2+ binding site [chemical binding]; other site
511145007698	Switch I region; other site
511145007699	G2 box; other site
511145007700	Switch II region; other site
511145007701	G3 box; other site
511145007702	G4 box; other site
511145007703	G5 box; other site
511145007704	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
511145007705	G1 box; other site
511145007706	GTP/Mg2+ binding site [chemical binding]; other site
511145007707	Switch I region; other site
511145007708	G2 box; other site
511145007709	G3 box; other site
511145007710	Switch II region; other site
511145007711	G4 box; other site
511145007712	G5 box; other site
511145007713	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
511145007714	outer membrane biogenesis protein BamB; Provisional; Region: PRK11138
511145007715	PQQ-dependent dehydrogenases and related proteins; Region: PQQ_DH_like; cd00216
511145007716	Trp docking motif [polypeptide binding]; other site
511145007717	active site
511145007718	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2976
511145007719	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4649
511145007720	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
511145007721	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
511145007722	dimer interface [polypeptide binding]; other site
511145007723	motif 1; other site
511145007724	active site
511145007725	motif 2; other site
511145007726	motif 3; other site
511145007727	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
511145007728	anticodon binding site; other site
511145007729	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
511145007730	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612
511145007731	cytoskeletal protein RodZ; Provisional; Region: PRK10856
511145007732	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145007733	non-specific DNA binding site [nucleotide binding]; other site
511145007734	salt bridge; other site
511145007735	sequence-specific DNA binding site [nucleotide binding]; other site
511145007736	Domain of unknown function (DUF4115); Region: DUF4115; pfam13464
511145007737	23S rRNA m2A2503 methyltransferase; Region: TIGR00048
511145007738	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145007739	FeS/SAM binding site; other site
511145007740	Nucleoside diphosphate kinase; Region: NDK; pfam00334
511145007741	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
511145007742	active site
511145007743	multimer interface [polypeptide binding]; other site
511145007744	penicillin-binding protein 1C; Provisional; Region: PRK11240
511145007745	Transglycosylase; Region: Transgly; pfam00912
511145007746	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
511145007747	Penicillin-Binding Protein C-terminus Family; Region: BiPBP_C; pfam06832
511145007748	Large extracellular alpha-helical protein [General function prediction only]; Region: COG2373
511145007749	MG2 domain; Region: A2M_N; pfam01835
511145007750	Alpha-2-macroglobulin family N-terminal region; Region: A2M_N_2; pfam07703
511145007751	Alpha-2-macroglobulin family; Region: A2M; pfam00207
511145007752	Proteins similar to alpha2-macroglobulin (alpha (2)-M).  Alpha (2)-M is a major carrier protein in serum. It is a broadly specific proteinase inhibitor.  The structural thioester of alpha (2)-M, is involved in the immobilization and entrapment of...; Region: A2M_like; cd02891
511145007753	surface patch; other site
511145007754	thioester region; other site
511145007755	specificity defining residues; other site
511145007756	3-mercaptopyruvate sulfurtransferase; Provisional; Region: sseA; PRK11493
511145007757	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
511145007758	active site residue [active]
511145007759	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
511145007760	active site residue [active]
511145007761	SseB protein N-terminal domain; Region: SseB; pfam07179
511145007762	enhanced serine sensitivity protein SseB; Provisional; Region: PRK11611
511145007763	SseB protein C-terminal domain; Region: SseB_C; pfam14581
511145007764	aminopeptidase B; Provisional; Region: PRK05015
511145007765	Peptidase; Region: DUF3663; pfam12404
511145007766	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
511145007767	interface (dimer of trimers) [polypeptide binding]; other site
511145007768	Substrate-binding/catalytic site; other site
511145007769	Zn-binding sites [ion binding]; other site
511145007770	hypothetical protein; Provisional; Region: PRK10721
511145007771	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145007772	catalytic loop [active]
511145007773	iron binding site [ion binding]; other site
511145007774	chaperone protein HscA; Provisional; Region: hscA; PRK05183
511145007775	Nucleotide-binding domain of HscA and similar proteins; Region: HscA_like_NBD; cd10236
511145007776	nucleotide binding site [chemical binding]; other site
511145007777	putative NEF/HSP70 interaction site [polypeptide binding]; other site
511145007778	SBD interface [polypeptide binding]; other site
511145007779	co-chaperone HscB; Provisional; Region: hscB; PRK05014
511145007780	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
511145007781	HSP70 interaction site [polypeptide binding]; other site
511145007782	HSCB C-terminal oligomerization domain; Region: HSCB_C; pfam07743
511145007783	iron-sulfur cluster assembly protein; Provisional; Region: iscA; PRK09502
511145007784	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
511145007785	trimerization site [polypeptide binding]; other site
511145007786	active site
511145007787	cysteine desulfurase; Provisional; Region: PRK14012
511145007788	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145007789	catalytic residue [active]
511145007790	DNA-binding transcriptional regulator IscR; Provisional; Region: PRK10857
511145007791	Rrf2 family protein; Region: rrf2_super; TIGR00738
511145007792	tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional; Region: PRK15114
511145007793	SpoU rRNA Methylase family; Region: SpoU_methylase; cl17307
511145007794	IMPase, inositol monophosphatase and related domains. A family of Mg++ dependent phosphatases, inhibited by lithium, many of which may act on inositol monophosphate substrate. They dephosphorylate inositol phosphate to generate inositol, which may be...; Region: IMPase; cd01639
511145007795	active site
511145007796	dimerization interface [polypeptide binding]; other site
511145007797	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
511145007798	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
511145007799	stationary phase inducible protein CsiE; Provisional; Region: PRK11564
511145007800	PRD domain; Region: PRD; pfam00874
511145007801	PRD domain; Region: PRD; pfam00874
511145007802	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145007803	LacY proton/sugar symporter; Region: LacY_symp; pfam01306
511145007804	putative substrate translocation pore; other site
511145007805	DNA-binding transcriptional regulator HcaR; Provisional; Region: PRK09906
511145007806	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145007807	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145007808	dimerization interface [polypeptide binding]; other site
511145007809	Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only]; Region: HcaE; COG4638
511145007810	Rieske domain; a [2Fe-2S] cluster binding domain commonly found in Rieske non-heme iron oxygenase (RO) systems such as naphthalene and biphenyl dioxygenases, as well as in plant/cyanobacterial chloroplast b6f and mitochondrial cytochrome bc(1) complexes; Region: Rieske; cl00938
511145007811	iron-sulfur cluster [ion binding]; other site
511145007812	[2Fe-2S] cluster binding site [ion binding]; other site
511145007813	C-terminal catalytic domain of the oxygenase alpha subunit of naphthalene 1,2-dioxygenase (NDO) and related aromatic ring hydroxylating dioxygenases; Region: RHO_alpha_C_NDO-like; cd08881
511145007814	beta subunit interface [polypeptide binding]; other site
511145007815	alpha subunit interface [polypeptide binding]; other site
511145007816	active site
511145007817	substrate binding site [chemical binding]; other site
511145007818	Fe binding site [ion binding]; other site
511145007819	Ring hydroxylating dioxygenase beta subunit. This subunit has a similar structure to NTF-2, Ketosteroid isomerase and scytalone dehydratase.The degradation of aromatic compounds by aerobic bacteria frequently begins with the dihydroxylation of the...; Region: ring_hydroxylating_dioxygenases_beta; cd00667
511145007820	inter-subunit interface; other site
511145007821	Rieske non-heme iron oxygenase (RO) family, Rieske ferredoxin component; composed of the Rieske ferredoxin component of some three-component RO systems including biphenyl dioxygenase (BPDO) and carbazole 1,9a-dioxygenase (CARDO). The RO family comprise a...; Region: Rieske_RO_ferredoxin; cd03528
511145007822	[2Fe-2S] cluster binding site [ion binding]; other site
511145007823	2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Provisional; Region: PRK06200
511145007824	cis-biphenyl-2,3-dihydrodiol-2,3-dehydrogenase (BphB)-like, classical (c) SDRs; Region: BphB-like_SDR_c; cd05348
511145007825	NAD binding site [chemical binding]; other site
511145007826	active site
511145007827	phenylpropionate dioxygenase ferredoxin reductase subunit; Provisional; Region: PRK09754
511145007828	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
511145007829	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145007830	Reductase C-terminal; Region: Reductase_C; pfam14759
511145007831	Predicted membrane protein [Function unknown]; Region: COG2259
511145007832	aldose 1-epimerase, similar to Escherichia coli YphB; Region: Aldose_epim_Ec_YphB; cd09021
511145007833	active site
511145007834	catalytic residues [active]
511145007835	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145007836	L-threonine dehydrogenase (TDH)-like; Region: THR_DH_like; cd08239
511145007837	putative NAD(P) binding site [chemical binding]; other site
511145007838	catalytic Zn binding site [ion binding]; other site
511145007839	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145007840	TM-ABC transporter signature motif; other site
511145007841	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
511145007842	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145007843	Walker A/P-loop; other site
511145007844	ATP binding site [chemical binding]; other site
511145007845	Q-loop/lid; other site
511145007846	ABC transporter signature motif; other site
511145007847	Walker B; other site
511145007848	D-loop; other site
511145007849	H-loop/switch region; other site
511145007850	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145007851	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
511145007852	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
511145007853	ligand binding site [chemical binding]; other site
511145007854	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145007855	TPR motif; other site
511145007856	Tetratricopeptide repeat; Region: TPR_16; pfam13432
511145007857	binding surface
511145007858	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145007859	binding surface
511145007860	Tetratricopeptide repeat; Region: TPR_16; pfam13432
511145007861	TPR motif; other site
511145007862	TPR repeat; Region: TPR_11; pfam13414
511145007863	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145007864	TPR motif; other site
511145007865	binding surface
511145007866	Winged helix-turn-helix DNA-binding; Region: HTH_24; pfam13412
511145007867	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145007868	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145007869	nucleotide binding site [chemical binding]; other site
511145007870	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
511145007871	dimer interface [polypeptide binding]; other site
511145007872	active site
511145007873	glycine-pyridoxal phosphate binding site [chemical binding]; other site
511145007874	folate binding site [chemical binding]; other site
511145007875	bifunctional nitric oxide dioxygenase/dihydropteridine reductase 2; Provisional; Region: PRK13289
511145007876	Globins are heme proteins, which bind and transport oxygen. This family summarizes a diverse set of homologous protein domains, including: (1) tetrameric vertebrate hemoglobins, which are the major protein component of erythrocytes and transport oxygen...; Region: globin; cd01040
511145007877	heme-binding site [chemical binding]; other site
511145007878	FAD_NAD(P)H binding domain of flavohemoglobin. Flavohemoglobins have a globin domain containing a B-type heme fused with a ferredoxin reductase-like FAD/NAD-binding domain. Flavohemoglobins detoxify nitric oxide (NO) via an NO dioxygenase reaction. The...; Region: flavohem_like_fad_nad_binding; cd06184
511145007879	FAD binding pocket [chemical binding]; other site
511145007880	FAD binding motif [chemical binding]; other site
511145007881	phosphate binding motif [ion binding]; other site
511145007882	beta-alpha-beta structure motif; other site
511145007883	NAD binding pocket [chemical binding]; other site
511145007884	Heme binding  pocket [chemical binding]; other site
511145007885	nitrogen regulatory protein P-II 1; Provisional; Region: PRK10858
511145007886	response regulator GlrR; Provisional; Region: PRK15115
511145007887	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145007888	active site
511145007889	phosphorylation site [posttranslational modification]
511145007890	intermolecular recognition site; other site
511145007891	dimerization interface [polypeptide binding]; other site
511145007892	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145007893	Walker A motif; other site
511145007894	ATP binding site [chemical binding]; other site
511145007895	Walker B motif; other site
511145007896	arginine finger; other site
511145007897	hypothetical protein; Provisional; Region: PRK10722
511145007898	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
511145007899	HAMP domain; Region: HAMP; pfam00672
511145007900	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145007901	dimer interface [polypeptide binding]; other site
511145007902	phosphorylation site [posttranslational modification]
511145007903	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145007904	ATP binding site [chemical binding]; other site
511145007905	Mg2+ binding site [ion binding]; other site
511145007906	G-X-G motif; other site
511145007907	phosphoribosylformylglycinamidine synthase; Provisional; Region: PRK05297
511145007908	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
511145007909	dimerization interface [polypeptide binding]; other site
511145007910	ATP binding site [chemical binding]; other site
511145007911	AIR (aminoimidazole ribonucleotide) synthase related protein. This family includes Hydrogen expression/formation protein HypE, AIR synthases, FGAM (formylglycinamidine ribonucleotide) synthase and Selenophosphate synthetase (SelD). The N-terminal domain...; Region: PurM-like; cl10019
511145007912	dimerization interface [polypeptide binding]; other site
511145007913	ATP binding site [chemical binding]; other site
511145007914	Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase; Region: GATase1_FGAR_AT; cd01740
511145007915	putative active site [active]
511145007916	catalytic triad [active]
511145007917	membrane-bound lytic transglycosylase F; Provisional; Region: PRK10859
511145007918	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145007919	substrate binding pocket [chemical binding]; other site
511145007920	membrane-bound complex binding site; other site
511145007921	hinge residues; other site
511145007922	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145007923	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145007924	catalytic residue [active]
511145007925	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
511145007926	nucleoside/Zn binding site; other site
511145007927	dimer interface [polypeptide binding]; other site
511145007928	catalytic motif [active]
511145007929	hypothetical protein; Provisional; Region: PRK11590
511145007930	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
511145007931	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
511145007932	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11557
511145007933	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
511145007934	putative active site [active]
511145007935	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
511145007936	holo-[acyl-carrier-protein] synthase; Region: acpS; TIGR00516
511145007937	Pyridoxine 5'-phosphate (PNP) synthase domain; pyridoxal 5'-phosphate is the active form of vitamin B6 that acts as an essential, ubiquitous coenzyme in amino acid metabolism. In bacteria, formation of pyridoxine 5'-phosphate is a step in...; Region: PNPsynthase; cd00003
511145007938	active site
511145007939	hydrophilic channel; other site
511145007940	dimerization interface [polypeptide binding]; other site
511145007941	catalytic residues [active]
511145007942	active site lid [active]
511145007943	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
511145007944	Recombination protein O N terminal; Region: RecO_N; pfam11967
511145007945	Recombination protein O C terminal; Region: RecO_C; pfam02565
511145007946	GTPase Era; Reviewed; Region: era; PRK00089
511145007947	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
511145007948	G1 box; other site
511145007949	GTP/Mg2+ binding site [chemical binding]; other site
511145007950	Switch I region; other site
511145007951	G2 box; other site
511145007952	Switch II region; other site
511145007953	G3 box; other site
511145007954	G4 box; other site
511145007955	G5 box; other site
511145007956	KH domain; Region: KH_2; pfam07650
511145007957	ribonuclease III; Reviewed; Region: rnc; PRK00102
511145007958	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
511145007959	dimerization interface [polypeptide binding]; other site
511145007960	active site
511145007961	metal binding site [ion binding]; metal-binding site
511145007962	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
511145007963	dsRNA binding site [nucleotide binding]; other site
511145007964	signal peptidase I; Provisional; Region: PRK10861
511145007965	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
511145007966	Catalytic site [active]
511145007967	GTP-binding protein LepA; Provisional; Region: PRK05433
511145007968	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
511145007969	G1 box; other site
511145007970	putative GEF interaction site [polypeptide binding]; other site
511145007971	GTP/Mg2+ binding site [chemical binding]; other site
511145007972	Switch I region; other site
511145007973	G2 box; other site
511145007974	G3 box; other site
511145007975	Switch II region; other site
511145007976	G4 box; other site
511145007977	G5 box; other site
511145007978	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
511145007979	Elongation Factor G, domain II; Region: EFG_II; pfam14492
511145007980	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
511145007981	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
511145007982	SoxR reducing system protein RseC; Provisional; Region: PRK10862
511145007983	anti-sigma E factor; Provisional; Region: rseB; PRK09455
511145007984	anti-RNA polymerase sigma factor SigE; Provisional; Region: PRK10863
511145007985	Anti sigma-E protein RseA, N-terminal domain; Region: RseA_N; pfam03872
511145007986	Anti sigma-E protein RseA, C-terminal domain; Region: RseA_C; pfam03873
511145007987	RNA polymerase sigma factor RpoE; Region: RpoE_Sigma70; TIGR02939
511145007988	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145007989	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145007990	DNA binding residues [nucleotide binding]
511145007991	L-aspartate oxidase; Provisional; Region: PRK09077
511145007992	L-aspartate oxidase; Provisional; Region: PRK06175
511145007993	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
511145007994	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
511145007995	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145007996	S-adenosylmethionine binding site [chemical binding]; other site
511145007997	ATP-dependent RNA helicase SrmB; Provisional; Region: PRK11192
511145007998	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
511145007999	ATP binding site [chemical binding]; other site
511145008000	Mg++ binding site [ion binding]; other site
511145008001	motif III; other site
511145008002	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145008003	nucleotide binding region [chemical binding]; other site
511145008004	ATP-binding site [chemical binding]; other site
511145008005	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145008006	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145008007	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
511145008008	dimerization interface [polypeptide binding]; other site
511145008009	cysteine/O-acetylserine exporter; Provisional; Region: PRK10323
511145008010	autonomous glycyl radical cofactor GrcA; Provisional; Region: PRK11127
511145008011	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
511145008012	ligand binding site [chemical binding]; other site
511145008013	active site
511145008014	UGI interface [polypeptide binding]; other site
511145008015	catalytic site [active]
511145008016	putative methyltransferase; Provisional; Region: PRK10864
511145008017	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
511145008018	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
511145008019	thioredoxin 2; Provisional; Region: PRK10996
511145008020	zinc-ribbon domain; Region: zinc_ribbon_5; cl11777
511145008021	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
511145008022	catalytic residues [active]
511145008023	Uncharacterized conserved protein [Function unknown]; Region: COG3148
511145008024	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
511145008025	CoA binding domain; Region: CoA_binding_2; pfam13380
511145008026	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
511145008027	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
511145008028	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
511145008029	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
511145008030	phosphatidylserine synthase; Provisional; Region: pssA; PRK09428
511145008031	Catalytic domain, repeat 1, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_1; cd09134
511145008032	domain interface [polypeptide binding]; other site
511145008033	putative active site [active]
511145008034	catalytic site [active]
511145008035	Catalytic domain, repeat 2, of phosphatidylserine synthases from gram-negative bacteria; Region: PLDc_PSS_G_neg_2; cd09136
511145008036	domain interface [polypeptide binding]; other site
511145008037	putative active site [active]
511145008038	catalytic site [active]
511145008039	lipoprotein; Provisional; Region: PRK10759
511145008040	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
511145008041	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008042	putative substrate translocation pore; other site
511145008043	protein disaggregation chaperone; Provisional; Region: PRK10865
511145008044	Clp amino terminal domain; Region: Clp_N; pfam02861
511145008045	Clp amino terminal domain; Region: Clp_N; pfam02861
511145008046	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145008047	Walker A motif; other site
511145008048	ATP binding site [chemical binding]; other site
511145008049	Walker B motif; other site
511145008050	arginine finger; other site
511145008051	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145008052	Walker A motif; other site
511145008053	ATP binding site [chemical binding]; other site
511145008054	Walker B motif; other site
511145008055	arginine finger; other site
511145008056	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
511145008057	hypothetical protein; Provisional; Region: PRK10723
511145008058	23S rRNA pseudouridine synthase D; Provisional; Region: rluD; PRK11180
511145008059	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145008060	RNA binding surface [nucleotide binding]; other site
511145008061	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
511145008062	active site
511145008063	outer membrane biogenesis protein BamD; Provisional; Region: PRK10866
511145008064	Protein of unknown function (DUF3897); Region: DUF3897; cl17494
511145008065	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
511145008066	30S subunit binding site; other site
511145008067	bifunctional chorismate mutase/prephenate dehydratase; Provisional; Region: pheA; PRK10622
511145008068	chorismate mutase domain of proteobacterial P-protein, clade 1; Region: CM_P_1; TIGR01797
511145008069	Prephenate dehydratase; Region: PDT; pfam00800
511145008070	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
511145008071	putative L-Phe binding site [chemical binding]; other site
511145008072	bifunctional chorismate mutase/prephenate dehydrogenase; Provisional; Region: tyrA; PRK11199
511145008073	chorismate mutase domain of T-protein; Region: CM_T; TIGR01799
511145008074	prephenate dehydrogenase; Validated; Region: PRK08507
511145008075	phospho-2-dehydro-3-deoxyheptonate aldolase; Provisional; Region: PRK12755
511145008076	lipoprotein; Provisional; Region: PRK11443
511145008077	Domain of unknown function (DUF4154); Region: DUF4154; pfam13689
511145008078	putative inner membrane diguanylate cyclase; Provisional; Region: PRK09966
511145008079	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145008080	metal binding site [ion binding]; metal-binding site
511145008081	active site
511145008082	I-site; other site
511145008083	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
511145008084	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
511145008085	ligand binding site [chemical binding]; other site
511145008086	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
511145008087	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
511145008088	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
511145008089	RimM N-terminal domain; Region: RimM; pfam01782
511145008090	PRC-barrel domain; Region: PRC; pfam05239
511145008091	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
511145008092	signal recognition particle protein; Provisional; Region: PRK10867
511145008093	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
511145008094	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
511145008095	P loop; other site
511145008096	GTP binding site [chemical binding]; other site
511145008097	Signal peptide binding domain; Region: SRP_SPB; pfam02978
511145008098	ABC-type uncharacterized transport system, permease component [General function prediction only]; Region: COG4137
511145008099	hypothetical protein; Provisional; Region: PRK11573
511145008100	Domain of unknown function DUF21; Region: DUF21; pfam01595
511145008101	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
511145008102	Transporter associated domain; Region: CorC_HlyC; smart01091
511145008103	Uncharacterized protein conserved in bacteria (DUF2317); Region: DUF2317; cl19511
511145008104	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
511145008105	dimer interface [polypeptide binding]; other site
511145008106	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
511145008107	inorganic polyphosphate/ATP-NAD kinase; Provisional; Region: ppnK; PRK03378
511145008108	recombination and repair protein; Provisional; Region: PRK10869
511145008109	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
511145008110	Walker A/P-loop; other site
511145008111	ATP binding site [chemical binding]; other site
511145008112	Q-loop/lid; other site
511145008113	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
511145008114	Q-loop/lid; other site
511145008115	ABC transporter signature motif; other site
511145008116	Walker B; other site
511145008117	D-loop; other site
511145008118	H-loop/switch region; other site
511145008119	outer membrane biogenesis protein BamE; Provisional; Region: PRK11548
511145008120	hypothetical protein; Validated; Region: PRK01777
511145008121	Coenzyme Q-binding protein COQ10p and similar proteins; Region: COQ10p_like; cd07813
511145008122	putative coenzyme Q binding site [chemical binding]; other site
511145008123	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
511145008124	SmpB-tmRNA interface; other site
511145008125	cryptic prophage CP4-57
511145008126	integrase; Provisional; Region: PRK09692
511145008127	Bacteriophage P4 integrase. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements.  They share the same fold in their catalytic domain and the overall...; Region: INT_P4; cd00801
511145008128	active site
511145008129	Int/Topo IB signature motif; other site
511145008130	Predicted transcriptional regulator [Transcription]; Region: AlpA; COG3311
511145008131	Protein of unknown function (DUF3987); Region: DUF3987; pfam13148
511145008132	Protein of unknown function (DUF3296); Region: DUF3296; pfam11726
511145008133	Superfamily II helicase [General function prediction only]; Region: COG1204
511145008134	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145008135	ATP binding site [chemical binding]; other site
511145008136	putative Mg++ binding site [ion binding]; other site
511145008137	helicase superfamily c-terminal domain; Region: HELICc; smart00490
511145008138	Domain of unknown function (DUF4297); Region: DUF4297; pfam14130
511145008139	Domain of unknown function (DUF1837); Region: DUF1837; pfam08878
511145008140	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
511145008141	Predicted GTPase [General function prediction only]; Region: COG3596
511145008142	YfjP GTPase; Region: YfjP; cd11383
511145008143	G1 box; other site
511145008144	GTP/Mg2+ binding site [chemical binding]; other site
511145008145	Switch I region; other site
511145008146	G2 box; other site
511145008147	Switch II region; other site
511145008148	G3 box; other site
511145008149	G4 box; other site
511145008150	G5 box; other site
511145008151	Domain of unknown function (DUF932); Region: DUF932; pfam06067
511145008152	Predicted transcriptional regulator [Transcription]; Region: COG2378
511145008153	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
511145008154	WYL domain; Region: WYL; pfam13280
511145008155	Predicted transcriptional regulator [Transcription]; Region: COG2378
511145008156	Antirestriction protein; Region: Antirestrict; pfam03230
511145008157	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
511145008158	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
511145008159	MPN+ (JAMM) motif; other site
511145008160	Zinc-binding site [ion binding]; other site
511145008161	Protein of unknown function (DUF987); Region: DUF987; pfam06174
511145008162	YagB/YeeU/YfjZ family; Region: YagB_YeeU_YfjZ; pfam06154
511145008163	Protein of unknown function (DUF1219); Region: DUF1219; pfam06755
511145008164	hypothetical protein; Provisional; Region: PRK09945
511145008165	Type V secretory pathway, adhesin AidA [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: AidA; COG3468
511145008166	hypothetical protein; Provisional; Region: PRK09945
511145008167	Pertactin-like passenger domains (virulence factors), C-terminal, subgroup 1, of autotransporter proteins of the type V secretion system of Gram-negative bacteria. This subgroup includes the passenger domains of Neisseria and Haemophilus IgA1 proteases; Region: PL1_Passenger_AT; cd01343
511145008168	outer membrane autotransporter barrel domain; Region: autotrans_barl; TIGR01414
511145008169	Autotransporter beta-domain; Region: Autotransporter; pfam03797
511145008170	Clavaminic acid synthetase (CAS) -like;  CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases...; Region: CAS_like; cd00250
511145008171	substrate binding pocket [chemical binding]; other site
511145008172	active site
511145008173	iron coordination sites [ion binding]; other site
511145008174	hydroxyglutarate oxidase; Provisional; Region: PRK11728
511145008175	Predicted dehydrogenase [General function prediction only]; Region: COG0579
511145008176	Mitochondrial succinate-semialdehyde dehydrogenase and ALDH family members 5A1 and 5F1-like; Region: ALDH_F5_SSADH_GabD; cd07103
511145008177	tetramerization interface [polypeptide binding]; other site
511145008178	NAD(P) binding site [chemical binding]; other site
511145008179	catalytic residues [active]
511145008180	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145008181	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145008182	inhibitor-cofactor binding pocket; inhibition site
511145008183	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145008184	catalytic residue [active]
511145008185	gamma-aminobutyrate transporter; Provisional; Region: PRK10197
511145008186	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145008187	DNA-binding transcriptional regulator CsiR; Provisional; Region: PRK11534
511145008188	helix_turn_helix gluconate operon transcriptional repressor; Region: HTH_GNTR; smart00345
511145008189	DNA-binding site [nucleotide binding]; DNA binding site
511145008190	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145008191	LysM domain/BON superfamily protein; Provisional; Region: PRK11198
511145008192	bacterial OsmY and nodulation domain; Region: BON; smart00749
511145008193	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145008194	Uncharacterized homolog of Blt101 [Function unknown]; Region: COG0401
511145008195	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145008196	dimerization interface [polypeptide binding]; other site
511145008197	putative DNA binding site [nucleotide binding]; other site
511145008198	Transcriptional regulators [Transcription]; Region: MarR; COG1846
511145008199	putative Zn2+ binding site [ion binding]; other site
511145008200	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YgaP, and similar uncharacterized putative rhodanese-related sulfurtransferases; Region: RHOD_YgaP; cd01527
511145008201	active site residue [active]
511145008202	Protein of unknown function (DUF2892); Region: DUF2892; pfam11127
511145008203	Domain in histone-like proteins of HNS family; Region: HNS; cl19571
511145008204	DNA binding protein, nucleoid-associated; Provisional; Region: PRK10328
511145008205	Protein of unknown function (DUF1144); Region: DUF1144; pfam06610
511145008206	hypothetical protein; Provisional; Region: PRK10556
511145008207	hypothetical protein; Provisional; Region: PRK10132
511145008208	NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase...; Region: NrdH; cd02976
511145008209	catalytic residues [active]
511145008210	ribonucleotide reductase stimulatory protein; Reviewed; Region: nrdI; PRK03600
511145008211	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK08188
511145008212	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
511145008213	Class I ribonucleotide reductase; Region: RNR_I; cd01679
511145008214	active site
511145008215	dimer interface [polypeptide binding]; other site
511145008216	catalytic residues [active]
511145008217	effector binding site; other site
511145008218	R2 peptide binding site; other site
511145008219	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
511145008220	dimer interface [polypeptide binding]; other site
511145008221	putative radical transfer pathway; other site
511145008222	diiron center [ion binding]; other site
511145008223	tyrosyl radical; other site
511145008224	glycine betaine transporter ATP-binding subunit; Provisional; Region: PRK10070
511145008225	ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; Region: ABC_Pro_Gly_Betaine; cd03294
511145008226	Walker A/P-loop; other site
511145008227	ATP binding site [chemical binding]; other site
511145008228	Q-loop/lid; other site
511145008229	ABC transporter signature motif; other site
511145008230	Walker B; other site
511145008231	D-loop; other site
511145008232	H-loop/switch region; other site
511145008233	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
511145008234	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
511145008235	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145008236	dimer interface [polypeptide binding]; other site
511145008237	conserved gate region; other site
511145008238	putative PBP binding loops; other site
511145008239	ABC-ATPase subunit interface; other site
511145008240	glycine betaine transporter periplasmic subunit; Provisional; Region: proX; PRK11119
511145008241	Predicted branched-chain amino acid permease (azaleucine resistance) [Amino acid transport and metabolism]; Region: AzlC; COG1296
511145008242	putative L-valine exporter; Provisional; Region: PRK10408
511145008243	transcriptional repressor MprA; Provisional; Region: PRK10870
511145008244	Transcriptional regulators [Transcription]; Region: MarR; COG1846
511145008245	multidrug efflux system protein EmrA; Provisional; Region: PRK15136
511145008246	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145008247	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145008248	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
511145008249	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008250	putative substrate translocation pore; other site
511145008251	S-ribosylhomocysteinase; Provisional; Region: PRK02260
511145008252	glutamate--cysteine ligase; Provisional; Region: PRK02107
511145008253	Predicted membrane protein [Function unknown]; Region: COG1238
511145008254	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
511145008255	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145008256	active site
511145008257	motif I; other site
511145008258	motif II; other site
511145008259	carbon storage regulator; Provisional; Region: PRK01712
511145008260	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
511145008261	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
511145008262	motif 1; other site
511145008263	active site
511145008264	motif 2; other site
511145008265	motif 3; other site
511145008266	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
511145008267	DHHA1 domain; Region: DHHA1; pfam02272
511145008268	recombination regulator RecX; Reviewed; Region: recX; PRK00117
511145008269	recombinase A; Provisional; Region: recA; PRK09354
511145008270	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
511145008271	hexamer interface [polypeptide binding]; other site
511145008272	Walker A motif; other site
511145008273	ATP binding site [chemical binding]; other site
511145008274	Walker B motif; other site
511145008275	hypothetical protein; Validated; Region: PRK03661
511145008276	murein hydrolase B; Provisional; Region: PRK10760
511145008277	lytic murein transglycosylase B; Region: MltB; TIGR02282
511145008278	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145008279	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145008280	PTS system, glucitol/sorbitol-specific, IIC component; Region: EII-GUT; TIGR00821
511145008281	PTS system, glucitol/sorbitol-specific, IIBC component; Region: EIIBC-GUT; TIGR00825
511145008282	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
511145008283	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
511145008284	PTS system glucitol/sorbitol-specific transporter subunit IIA; Provisional; Region: PRK10377
511145008285	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
511145008286	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
511145008287	putative NAD(P) binding site [chemical binding]; other site
511145008288	active site
511145008289	DNA-binding transcriptional activator GutM; Provisional; Region: PRK10234
511145008290	DNA-bindng transcriptional repressor SrlR; Provisional; Region: srlR; PRK10434
511145008291	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145008292	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145008293	D-arabinose 5-phosphate isomerase; Provisional; Region: gutQ; PRK11543
511145008294	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
511145008295	putative active site [active]
511145008296	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
511145008297	anaerobic nitric oxide reductase transcription regulator; Provisional; Region: PRK05022
511145008298	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145008299	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145008300	Walker A motif; other site
511145008301	ATP binding site [chemical binding]; other site
511145008302	Walker B motif; other site
511145008303	arginine finger; other site
511145008304	anaerobic nitric oxide reductase flavorubredoxin; Provisional; Region: PRK05452
511145008305	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
511145008306	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
511145008307	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
511145008308	iron binding site [ion binding]; other site
511145008309	NADH:flavorubredoxin oxidoreductase; Provisional; Region: PRK04965
511145008310	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145008311	Acylphosphatase; Region: Acylphosphatase; pfam00708
511145008312	[NiFe] hydrogenase maturation protein HypF; Region: hypF; TIGR00143
511145008313	HypF finger; Region: zf-HYPF; pfam07503
511145008314	HypF finger; Region: zf-HYPF; pfam07503
511145008315	Telomere recombination; Region: Sua5_yciO_yrdC; pfam01300
511145008316	formate dehydrogenase-H ferredoxin subunit; Provisional; Region: PRK10330
511145008317	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008318	Transcriptional regulators [Transcription]; Region: PurR; COG1609
511145008319	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145008320	DNA binding site [nucleotide binding]
511145008321	domain linker motif; other site
511145008322	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
511145008323	dimerization interface (closed form) [polypeptide binding]; other site
511145008324	ligand binding site [chemical binding]; other site
511145008325	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
511145008326	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145008327	active site turn [active]
511145008328	phosphorylation site [posttranslational modification]
511145008329	PTS system, maltose and glucose-specific subfamily, IIC component; Region: pts-Glc; TIGR00852
511145008330	cryptic 6-phospho-beta-glucosidase; Provisional; Region: PRK09852
511145008331	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
511145008332	Endopeptidases belonging to membrane-bound hydrogen evolving hydrogenase group. In hydrogenase 3 from E coli, the maturation of the large subunit (HycE) requires the cleavage of a C-terminal peptide by the endopeptidase HycI, before the final formation...; Region: H2MP_MemB-H2evol; cd06067
511145008333	nickel binding site [ion binding]; other site
511145008334	formate hydrogenlyase maturation protein HycH; Provisional; Region: PRK15084
511145008335	Ni,Fe-hydrogenase III small subunit [Energy production and conversion]; Region: COG3260
511145008336	formate hydrogenlyase complex iron-sulfur subunit; Provisional; Region: PRK12387
511145008337	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008338	Ni,Fe-hydrogenase III component G [Energy production and conversion]; Region: HycE; COG3262
511145008339	Ni,Fe-hydrogenase III large subunit [Energy production and conversion]; Region: HycE; COG3261
511145008340	NADH:ubiquinone oxidoreductase 49 kD subunit 7 [Energy production and conversion]; Region: NuoD; COG0649
511145008341	Formate hydrogenlyase subunit 4 [Energy production and conversion]; Region: HyfC; COG0650
511145008342	formate hydrogenlyase subunit 3; Reviewed; Region: PRK08042
511145008343	NADH-Ubiquinone/plastoquinone (complex I), various chains; Region: Oxidored_q1; pfam00361
511145008344	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
511145008345	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008346	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008347	formate hydrogenlyase regulatory protein HycA; Provisional; Region: PRK10198
511145008348	hydrogenase nickel incorporation protein; Validated; Region: hypA; PRK03681
511145008349	hydrogenase nickel incorporation protein HypB; Provisional; Region: PRK10463
511145008350	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
511145008351	hydrogenase assembly chaperone; Provisional; Region: PRK10409
511145008352	hydrogenase expression/formation protein HypD; Region: hypD; TIGR00075
511145008353	HypE (Hydrogenase expression/formation protein). HypE is involved in Ni-Fe hydrogenase biosynthesis.  HypE dehydrates its own carbamoyl moiety in an ATP-dependent process to yield the enzyme thiocyanate. The N-terminal domain of HypE is related to the...; Region: HypE; cd02197
511145008354	dimerization interface [polypeptide binding]; other site
511145008355	hydrogenase expression/formation protein HypE; Region: hypE; TIGR02124
511145008356	ATP binding site [chemical binding]; other site
511145008357	formate hydrogenlyase transcriptional activator FhlA; Provisional; Region: PRK15429
511145008358	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145008359	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145008360	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145008361	Walker A motif; other site
511145008362	ATP binding site [chemical binding]; other site
511145008363	Walker B motif; other site
511145008364	arginine finger; other site
511145008365	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
511145008366	Nitrous oxide-stimulated promoter; Region: YgbA_NO; pfam11756
511145008367	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
511145008368	MutS domain I; Region: MutS_I; pfam01624
511145008369	MutS domain II; Region: MutS_II; pfam05188
511145008370	MutS domain III; Region: MutS_III; pfam05192
511145008371	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
511145008372	Walker A/P-loop; other site
511145008373	ATP binding site [chemical binding]; other site
511145008374	Q-loop/lid; other site
511145008375	ABC transporter signature motif; other site
511145008376	Walker B; other site
511145008377	D-loop; other site
511145008378	H-loop/switch region; other site
511145008379	PrpA and PrpB, metallophosphatase domain; Region: MPP_PrpA_PrpB; cd07424
511145008380	active site
511145008381	metal binding site [ion binding]; metal-binding site
511145008382	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
511145008383	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
511145008384	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145008385	3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism]; Region: MmsB; COG2084
511145008386	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
511145008387	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
511145008388	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
511145008389	putative aldolase; Validated; Region: PRK08130
511145008390	intersubunit interface [polypeptide binding]; other site
511145008391	active site
511145008392	Zn2+ binding site [ion binding]; other site
511145008393	Hydroxypyruvate isomerase [Carbohydrate transport and metabolism]; Region: Hfi; COG3622
511145008394	hypothetical protein; Provisional; Region: PRK09989
511145008395	putative transporter; Provisional; Region: PRK09821
511145008396	GntP family permease; Region: GntP_permease; pfam02447
511145008397	RNA polymerase sigma factor RpoS; Validated; Region: PRK05657
511145008398	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
511145008399	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145008400	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
511145008401	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145008402	DNA binding residues [nucleotide binding]
511145008403	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
511145008404	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145008405	Peptidase family M23; Region: Peptidase_M23; pfam01551
511145008406	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145008407	S-adenosylmethionine binding site [chemical binding]; other site
511145008408	5'(3')-nucleotidase/polyphosphatase; Provisional; Region: surE; PRK00346
511145008409	Pseudouridine synthase, similar to Escherichia coli TruD; Region: PseudoU_synth_EcTruD; cd02575
511145008410	Permutation of conserved domain; other site
511145008411	active site
511145008412	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
511145008413	homotrimer interaction site [polypeptide binding]; other site
511145008414	zinc binding site [ion binding]; other site
511145008415	CDP-binding sites; other site
511145008416	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
511145008417	substrate binding site; other site
511145008418	dimer interface; other site
511145008419	cell division protein FtsB; Reviewed; Region: ftsB; PRK00888
511145008420	Protein of unknown function (DUF3561); Region: DUF3561; pfam12084
511145008421	Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form...; Region: APSK; cd02027
511145008422	ligand-binding site [chemical binding]; other site
511145008423	sulfate adenylyltransferase subunit 1; Provisional; Region: cysN; PRK05124
511145008424	CysN, together with protein CysD, forms the ATP sulfurylase (ATPS) complex; Region: CysN_ATPS; cd04166
511145008425	CysD dimerization site [polypeptide binding]; other site
511145008426	G1 box; other site
511145008427	putative GEF interaction site [polypeptide binding]; other site
511145008428	GTP/Mg2+ binding site [chemical binding]; other site
511145008429	Switch I region; other site
511145008430	G2 box; other site
511145008431	G3 box; other site
511145008432	Switch II region; other site
511145008433	G4 box; other site
511145008434	G5 box; other site
511145008435	CysN_NodQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NodQ_II; cd03695
511145008436	TCysN_NoDQ_II: This subfamily represents the domain II of the large subunit of ATP sulfurylase (ATPS): CysN or the N-terminal portion of NodQ, found mainly in proteobacteria and homologous to the domain II of EF-Tu. Escherichia coli ATPS consists of CysN...; Region: CysN_NoDQ_III; cd04095
511145008437	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
511145008438	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
511145008439	Active Sites [active]
511145008440	alkaline phosphatase isozyme conversion aminopeptidase; Provisional; Region: PRK10199
511145008441	M28 Zn-peptidases include aminopeptidases and carboxypeptidases; Region: M28; cd02690
511145008442	metal binding site [ion binding]; metal-binding site
511145008443	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I-E; cd09648
511145008444	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-E; cd09719
511145008445	CRISPR/Cas system-associated RAMP superfamily protein Cas6e; Region: Cas6_I-E; cd09664
511145008446	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-E; cd09645
511145008447	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-E; cd09646
511145008448	CRISPR/Cas system-associated protein Cse2; Region: Cse2_I-E; cd09670
511145008449	CRISPR/Cas system-associated protein Cse1; Region: Cse1_I-E; cd09669
511145008450	helicase Cas3; Provisional; Region: PRK09694
511145008451	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
511145008452	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
511145008453	3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes [Amino acid transport and metabolism / Coenzyme metabolism]; Region: CysH; COG0175
511145008454	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
511145008455	Active Sites [active]
511145008456	sulfite reductase subunit beta; Provisional; Region: PRK13504
511145008457	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
511145008458	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
511145008459	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
511145008460	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008461	sulfite reductase subunit alpha; Provisional; Region: cysJ; PRK10953
511145008462	Flavodoxin; Region: Flavodoxin_1; pfam00258
511145008463	Cytochrome p450- like alpha subunits of E. coli sulfite reductase (SiR) multimerize with beta subunits to catalyze the NADPH dependent reduction of sulfite to sulfide. Beta subunits have an Fe4S4 cluster and a siroheme, while the alpha subunits (cysJ...; Region: SiR; cd06199
511145008464	FAD binding pocket [chemical binding]; other site
511145008465	FAD binding motif [chemical binding]; other site
511145008466	catalytic residues [active]
511145008467	NAD binding pocket [chemical binding]; other site
511145008468	phosphate binding motif [ion binding]; other site
511145008469	beta-alpha-beta structure motif; other site
511145008470	6-pyruvoyl tetrahydropterin synthase (PTPS). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids, as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after uptake by a...; Region: PTPS; cd00470
511145008471	homohexamer interface [polypeptide binding]; other site
511145008472	putative substrate stabilizing pore; other site
511145008473	pterin binding site; other site
511145008474	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145008475	putative oxidoreductase FixC; Provisional; Region: PRK10157
511145008476	Ferredoxin-like protein [Energy production and conversion]; Region: FixX; COG2440
511145008477	Glycerol-3-phosphate responsive antiterminator (mRNA-binding) [Transcription]; Region: GlpP; COG1954
511145008478	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
511145008479	Adenine nucleotide alpha hydrolases superfamily including N type ATP PPases, ATP sulphurylases Universal Stress Response protein and electron transfer flavoprotein (ETF). The domain forms a apha/beta/apha fold which  binds to Adenosine nucleotide; Region: AANH_like; cl00292
511145008480	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
511145008481	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
511145008482	Ligand binding site [chemical binding]; other site
511145008483	Protein of unknown function (DUF2950); Region: DUF2950; pfam11453
511145008484	benzoate transport; Region: 2A0115; TIGR00895
511145008485	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008486	putative substrate translocation pore; other site
511145008487	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
511145008488	FAD binding domain; Region: FAD_binding_4; pfam01565
511145008489	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
511145008490	2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Region: PRK06935
511145008491	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
511145008492	NADP binding site [chemical binding]; other site
511145008493	homodimer interface [polypeptide binding]; other site
511145008494	active site
511145008495	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145008496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008497	putative substrate translocation pore; other site
511145008498	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
511145008499	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
511145008500	nucleotide binding site [chemical binding]; other site
511145008501	Organic radical activating enzymes [Posttranslational modification, protein turnover, chaperones]; Region: NrdG; COG0602
511145008502	putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE; Region: rSAM_QueE_Ecoli; TIGR04322
511145008503	Beta-propeller domains of methanol dehydrogenase type [General function prediction only]; Region: COG1512
511145008504	enolase; Provisional; Region: eno; PRK00077
511145008505	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
511145008506	dimer interface [polypeptide binding]; other site
511145008507	metal binding site [ion binding]; metal-binding site
511145008508	substrate binding pocket [chemical binding]; other site
511145008509	CTP synthetase; Validated; Region: pyrG; PRK05380
511145008510	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
511145008511	Catalytic site [active]
511145008512	active site
511145008513	UTP binding site [chemical binding]; other site
511145008514	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
511145008515	active site
511145008516	putative oxyanion hole; other site
511145008517	catalytic triad [active]
511145008518	nucleoside triphosphate pyrophosphohydrolase; Reviewed; Region: mazG; PRK09562
511145008519	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
511145008520	homodimer interface [polypeptide binding]; other site
511145008521	metal binding site [ion binding]; metal-binding site
511145008522	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
511145008523	homodimer interface [polypeptide binding]; other site
511145008524	active site
511145008525	putative chemical substrate binding site [chemical binding]; other site
511145008526	metal binding site [ion binding]; metal-binding site
511145008527	toxin MazF; Provisional; Region: PRK09907
511145008528	antitoxin MazE; Provisional; Region: PRK09798
511145008529	(p)ppGpp synthetase I/GTP pyrophosphokinase; Provisional; Region: relA; PRK10872
511145008530	HD domain; Region: HD_4; pfam13328
511145008531	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
511145008532	synthetase active site [active]
511145008533	NTP binding site [chemical binding]; other site
511145008534	metal binding site [ion binding]; metal-binding site
511145008535	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
511145008536	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
511145008537	23S rRNA m(5)U1939 methyltransferase; Reviewed; Region: rumA; PRK13168
511145008538	TRAM domain; Region: TRAM; pfam01938
511145008539	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145008540	S-adenosylmethionine binding site [chemical binding]; other site
511145008541	hybrid sensory histidine kinase BarA; Provisional; Region: PRK11107
511145008542	Uncharacterized signal transduction histidine kinase domain (DUF2222); Region: DUF2222; pfam09984
511145008543	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145008544	dimerization interface [polypeptide binding]; other site
511145008545	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145008546	dimer interface [polypeptide binding]; other site
511145008547	phosphorylation site [posttranslational modification]
511145008548	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145008549	ATP binding site [chemical binding]; other site
511145008550	Mg2+ binding site [ion binding]; other site
511145008551	G-X-G motif; other site
511145008552	Uncharacterized domain of BarA-like signal transduction histidine kinases [Signal transduction mechanisms]; Region: COG4999
511145008553	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145008554	active site
511145008555	phosphorylation site [posttranslational modification]
511145008556	intermolecular recognition site; other site
511145008557	dimerization interface [polypeptide binding]; other site
511145008558	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145008559	putative binding surface; other site
511145008560	active site
511145008561	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
511145008562	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
511145008563	active site
511145008564	tetramer interface [polypeptide binding]; other site
511145008565	glucarate dehydratase; Region: glucar-dehydr; TIGR03247
511145008566	D-Glucarate dehydratase (GlucD) catalyzes the dehydration of both D-glucarate and L-idarate to form 5-keto-4-deoxy-D-glucarate (5-KDG) , the initial reaction of the catabolic pathway for (D)-glucarate. GlucD belongs to the enolase superfamily of enzymes; Region: D-glucarate_dehydratase; cd03323
511145008567	active site
511145008568	tetramer interface [polypeptide binding]; other site
511145008569	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008570	D-galactonate transporter; Region: 2A0114; TIGR00893
511145008571	putative substrate translocation pore; other site
511145008572	flavodoxin; Provisional; Region: PRK08105
511145008573	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
511145008574	tRNA pseudouridine isomerase C; Region: PseudoU_synth_TruC; cd02563
511145008575	probable active site [active]
511145008576	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3098
511145008577	SecY interacting protein Syd; Provisional; Region: PRK04968
511145008578	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2904
511145008579	7-cyano-7-deazaguanine reductase; Provisional; Region: queF; PRK11792
511145008580	Enzyme related to GTP cyclohydrolase I [General function prediction only]; Region: COG0780
511145008581	Domain of unknown function (DUF4478); Region: DUF4478; pfam14793
511145008582	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
511145008583	Domain of unknown function (DUF3412); Region: DUF3412; pfam11892
511145008584	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145008585	serine transporter; Region: stp; TIGR00814
511145008586	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
511145008587	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
511145008588	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
511145008589	flap endonuclease-like protein; Provisional; Region: PRK09482
511145008590	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
511145008591	active site
511145008592	metal binding site 1 [ion binding]; metal-binding site
511145008593	putative 5' ssDNA interaction site; other site
511145008594	metal binding site 3; metal-binding site
511145008595	metal binding site 2 [ion binding]; metal-binding site
511145008596	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
511145008597	putative DNA binding site [nucleotide binding]; other site
511145008598	putative metal binding site [ion binding]; other site
511145008599	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
511145008600	dimer interface [polypeptide binding]; other site
511145008601	active site
511145008602	metal binding site [ion binding]; metal-binding site
511145008603	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
511145008604	intersubunit interface [polypeptide binding]; other site
511145008605	active site
511145008606	Zn2+ binding site [ion binding]; other site
511145008607	Fucose permease [Carbohydrate transport and metabolism]; Region: FucP; COG0738
511145008608	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008609	putative substrate translocation pore; other site
511145008610	L-fucose isomerase; Provisional; Region: fucI; PRK10991
511145008611	L-fucose isomerase (FucIase); FucIase converts L-fucose, an aldohexose, to its ketose form, which prepares it for aldol cleavage (similar to the isomerization of glucose during glycolysis). L-fucose (or 6-deoxy-L-galactose) is found in blood group...; Region: L-fucose_isomerase; cd03556
511145008612	hexamer (dimer of trimers) interface [polypeptide binding]; other site
511145008613	trimer interface [polypeptide binding]; other site
511145008614	substrate binding site [chemical binding]; other site
511145008615	Mn binding site [ion binding]; other site
511145008616	L-fuculokinase; Provisional; Region: PRK10331
511145008617	L-fuculose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_FK; cd07773
511145008618	putative N- and C-terminal domain interface [polypeptide binding]; other site
511145008619	putative active site [active]
511145008620	putative MgATP binding site [chemical binding]; other site
511145008621	putative catalytic site [active]
511145008622	metal binding site [ion binding]; metal-binding site
511145008623	putative carbohydrate binding site [chemical binding]; other site
511145008624	L-fucose mutarotase; Provisional; Region: fucU; PRK15420
511145008625	DNA-binding transcriptional activator FucR; Provisional; Region: PRK10411
511145008626	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145008627	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145008628	putative 23S rRNA C2498 ribose 2'-O-ribose methyltransferase; Provisional; Region: PRK11760
511145008629	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
511145008630	hypothetical protein; Provisional; Region: PRK10873
511145008631	DNA-binding transcriptional activator GcvA; Provisional; Region: PRK11139
511145008632	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145008633	The C-terminal substrate domain of LysR-type GcdR, TrPI, HvR and beta-lactamase regulators, and that of other closely related homologs; contains the type 2 periplasmic binding fold; Region: PBP2_GcdR_TrpI_HvrB_AmpR_like; cd08432
511145008634	dimerization interface [polypeptide binding]; other site
511145008635	substrate binding pocket [chemical binding]; other site
511145008636	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
511145008637	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
511145008638	histidinol-phosphate aminotransferase; Region: hisC; TIGR01141
511145008639	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145008640	catalytic residue [active]
511145008641	CsdA-binding activator; Provisional; Region: PRK15019
511145008642	sulfur acceptor protein CsdL; Provisional; Region: PRK15116
511145008643	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
511145008644	putative ATP binding site [chemical binding]; other site
511145008645	putative substrate interface [chemical binding]; other site
511145008646	murein transglycosylase A; Provisional; Region: mltA; PRK11162
511145008647	MltA specific insert domain; Region: MltA; smart00925
511145008648	3D domain; Region: 3D; pfam06725
511145008649	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
511145008650	AMIN domain; Region: AMIN; pfam11741
511145008651	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
511145008652	active site
511145008653	metal binding site [ion binding]; metal-binding site
511145008654	N-acetylglutamate synthase; Validated; Region: PRK05279
511145008655	AAK_NAGS-ABP: N-acetylglutamate (NAG) kinase-like domain of the NAG Synthase (NAGS) of the arginine-biosynthesis pathway (ABP) found in gamma- and beta-proteobacteria and higher plant chloroplasts. Domain architecture of these NAGS consisted of an...; Region: AAK_NAGS-ABP; cd04237
511145008656	putative feedback inhibition sensing region; other site
511145008657	putative nucleotide binding site [chemical binding]; other site
511145008658	putative substrate binding site [chemical binding]; other site
511145008659	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145008660	Coenzyme A binding pocket [chemical binding]; other site
511145008661	exonuclease V subunit alpha; Provisional; Region: recD; PRK10875
511145008662	Helicase; Region: Helicase_RecD; pfam05127
511145008663	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
511145008664	exonuclease V subunit beta; Provisional; Region: recB; PRK10876
511145008665	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
511145008666	protease3; Provisional; Region: PRK15101
511145008667	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
511145008668	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
511145008669	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
511145008670	exonuclease V subunit gamma; Provisional; Region: recC; PRK11069
511145008671	exodeoxyribonuclease V, gamma subunit; Region: recC; TIGR01450
511145008672	hypothetical protein; Provisional; Region: PRK10332
511145008673	Tfp pilus assembly protein PilV [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilV; COG4967
511145008674	hypothetical protein; Provisional; Region: PRK11521
511145008675	hypothetical protein; Provisional; Region: PRK10557
511145008676	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
511145008677	hypothetical protein; Provisional; Region: PRK10506
511145008678	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
511145008679	Bacterial shufflon protein, N-terminal constant region; Region: Shufflon_N; pfam04917
511145008680	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
511145008681	dimerization interface [polypeptide binding]; other site
511145008682	active site
511145008683	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
511145008684	fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain; Provisional; Region: PRK11061
511145008685	Domain present in phytochromes and cGMP-specific phosphodiesterases; Region: GAF; smart00065
511145008686	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
511145008687	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145008688	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
511145008689	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Members of this family are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_plant_like; cd03671
511145008690	putative active site [active]
511145008691	Ap4A binding site [chemical binding]; other site
511145008692	nudix motif; other site
511145008693	putative metal binding site [ion binding]; other site
511145008694	MutH is a 28kD endonuclease involved in methyl-directed DNA mismatch repair in gram negative bacteria. MutH is both sequence-specific and methylation-specific, introducing a nick in the unmethylated strand of a hemi-methylated d(GATC) DNA duplex.   MutH...; Region: MutH_Sau3AI; cd00583
511145008695	putative DNA-binding cleft [nucleotide binding]; other site
511145008696	putative DNA clevage site; other site
511145008697	molecular lever; other site
511145008698	Membrane protein TerC, possibly involved in tellurium resistance [Inorganic ion transport and metabolism]; Region: TerC; COG0861
511145008699	Bacterial protein of unknown function (DUF903); Region: DUF903; pfam06004
511145008700	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145008701	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145008702	active site
511145008703	catalytic tetrad [active]
511145008704	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008705	putative substrate translocation pore; other site
511145008706	bifunctional acyl-[acyl carrier protein] synthetase/2-acylglycerophosphoethanolamine acyltransferase; Validated; Region: PRK08043
511145008707	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
511145008708	putative acyl-acceptor binding pocket; other site
511145008709	C-terminal domain of the acyl-acyl carrier protein synthetase (also called 2-acylglycerophosphoethanolamine acyltransferase, Aas); Region: AAS_C; cd05909
511145008710	acyl-activating enzyme (AAE) consensus motif; other site
511145008711	putative AMP binding site [chemical binding]; other site
511145008712	DNA-binding transcriptional regulator GalR; Provisional; Region: PRK10727
511145008713	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145008714	DNA binding site [nucleotide binding]
511145008715	domain linker motif; other site
511145008716	Ligand binding domain of DNA transcription iso-repressor GalS, which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalS_like; cd06270
511145008717	dimerization interface (closed form) [polypeptide binding]; other site
511145008718	ligand binding site [chemical binding]; other site
511145008719	diaminopimelate decarboxylase; Provisional; Region: PRK11165
511145008720	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
511145008721	active site
511145008722	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145008723	substrate binding site [chemical binding]; other site
511145008724	catalytic residues [active]
511145008725	dimer interface [polypeptide binding]; other site
511145008726	DNA-binding transcriptional regulator LysR; Provisional; Region: PRK11013
511145008727	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145008728	The C-terminal substrate binding domain of LysR, transcriptional regulator for lysine biosynthesis, contains the type 2 periplasmic binding fold; Region: PBP2_LysR; cd08456
511145008729	putative dimerization interface [polypeptide binding]; other site
511145008730	putative racemase; Provisional; Region: PRK10200
511145008731	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
511145008732	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145008733	putative substrate translocation pore; other site
511145008734	2-deoxy-D-gluconate 3-dehydrogenase; Validated; Region: PRK08993
511145008735	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
511145008736	NADP binding site [chemical binding]; other site
511145008737	homodimer interface [polypeptide binding]; other site
511145008738	active site
511145008739	5-keto-4-deoxyuronate isomerase; Provisional; Region: PRK00924
511145008740	putative acyltransferase; Provisional; Region: PRK05790
511145008741	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
511145008742	dimer interface [polypeptide binding]; other site
511145008743	active site
511145008744	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145008745	serine transporter; Region: stp; TIGR00814
511145008746	DNA-binding HTH domain-containing proteins [Transcription]; Region: CsgD; COG2771
511145008747	DNA binding residues [nucleotide binding]
511145008748	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
511145008749	Uncharacterized protein conserved in Bacteroidetes; Region: Bacuni_01323_like; cd12871
511145008750	hyperosmolarity resistance protein Ebh, N-terminal domain; Region: hyperosmo_Ebh; TIGR04264
511145008751	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
511145008752	Tetratricopeptide repeat; Region: TPR_3; pfam07720
511145008753	Tetratricopeptide repeat; Region: TPR_3; pfam07720
511145008754	transcriptional regulator; Provisional; Region: PRK11906
511145008755	DNA-binding winged-HTH domains [Transcription]; Region: CadC; COG3710
511145008756	DNA binding site [nucleotide binding]
511145008757	Tetratricopeptide repeat; Region: TPR_2; pfam07719
511145008758	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145008759	HTH-like domain; Region: HTH_21; pfam13276
511145008760	Integrase core domain; Region: rve; pfam00665
511145008761	Integrase core domain; Region: rve_3; pfam13683
511145008762	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145008763	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145008764	lipoprotein NlpD; Provisional; Region: nlpD; PRK10871
511145008765	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
511145008766	Peptidase family M23; Region: Peptidase_M23; pfam01551
511145008767	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
511145008768	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
511145008769	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
511145008770	xanthine dehydrogenase subunit XdhB; Provisional; Region: PRK09971
511145008771	FAD binding domain in molybdopterin dehydrogenase; Region: FAD_binding_5; pfam00941
511145008772	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
511145008773	xanthine dehydrogenase subunit XdhC; Provisional; Region: PRK09908
511145008774	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
511145008775	catalytic loop [active]
511145008776	iron binding site [ion binding]; other site
511145008777	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
511145008778	GAF domain; Region: GAF; cl17456
511145008779	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
511145008780	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145008781	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145008782	Walker A motif; other site
511145008783	ATP binding site [chemical binding]; other site
511145008784	Walker B motif; other site
511145008785	arginine finger; other site
511145008786	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145008787	aspartate/ornithine carbamoyltransferase family protein; Validated; Region: PRK07200
511145008788	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
511145008789	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
511145008790	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
511145008791	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145008792	catalytic residue [active]
511145008793	peptidase; Reviewed; Region: PRK13004
511145008794	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
511145008795	putative metal binding site [ion binding]; other site
511145008796	putative dimer interface [polypeptide binding]; other site
511145008797	D-hydantoinase; Region: D-hydantoinase; TIGR02033
511145008798	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
511145008799	tetramer interface [polypeptide binding]; other site
511145008800	active site
511145008801	AAK_CK: Carbamate kinase (CK) catalyzes both the ATP-phosphorylation of carbamate and carbamoyl phosphate (CP) utilization with the production of ATP from ADP and CP. Both CK (this CD) and nonhomologous CP synthetase synthesize carbamoyl phosphate, an...; Region: AAK_CK; cd04235
511145008802	putative substrate binding site [chemical binding]; other site
511145008803	nucleotide binding site [chemical binding]; other site
511145008804	nucleotide binding site [chemical binding]; other site
511145008805	homodimer interface [polypeptide binding]; other site
511145008806	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
511145008807	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
511145008808	XdhC Rossmann domain; Region: XdhC_C; pfam13478
511145008809	selenium-dependent molybdenum hydroxylase system protein, YqeB family; Region: matur_yqeB; TIGR03309
511145008810	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
511145008811	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
511145008812	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
511145008813	Ligand binding site; other site
511145008814	metal-binding site
511145008815	putative selenate reductase subunit YgfK; Provisional; Region: PRK09853
511145008816	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
511145008817	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008818	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145008819	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
511145008820	putative selenium metabolism protein SsnA; Region: Se_ssnA; TIGR03314
511145008821	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
511145008822	active site
511145008823	putative substrate binding pocket [chemical binding]; other site
511145008824	FAD binding domain; Region: FAD_binding_4; cl19922
511145008825	probable selenate reductase, FAD-binding subunit; Region: Se_sel_red_FAD; TIGR03312
511145008826	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
511145008827	probable selenate reductase, molybdenum-binding subunit; Region: Se_sel_red_Mo; TIGR03313
511145008828	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
511145008829	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; pfam01315
511145008830	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
511145008831	uracil-xanthine permease; Region: ncs2; TIGR00801
511145008832	Sulfate transporter family; Region: Sulfate_transp; cl19250
511145008833	guanine deaminase; Provisional; Region: PRK09228
511145008834	Guanine deaminase (GDEase). Guanine deaminase is an aminohydrolase responsible for the conversion of guanine to xanthine and ammonia, the first step to utilize guanine as a nitrogen source. This reaction also removes the guanine base from the pool and...; Region: GDEase; cd01303
511145008835	active site
511145008836	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
511145008837	Sulfate transporter family; Region: Sulfate_transp; cl19250
511145008838	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
511145008839	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008840	putative oxidoreductase Fe-S binding subunit; Reviewed; Region: PRK12809
511145008841	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145008842	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
511145008843	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; cl19126
511145008844	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
511145008845	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145008846	Sulfate transporter family; Region: Sulfate_transp; cl19250
511145008847	xanthine permease; Region: pbuX; TIGR03173
511145008848	Isopentenyldiphosphate isomerase [Lipid metabolism]; Region: Idi; COG1443
511145008849	Isopentenyl diphosphate (IPP) isomerase, a member of the Nudix hydrolase superfamily, is a key enzyme in the isoprenoid biosynthetic pathway. Isoprenoids comprise a large family of natural products including sterols, carotenoids, dolichols and prenylated...; Region: IPP_Isomerase; cd02885
511145008850	active site
511145008851	metal binding site [ion binding]; metal-binding site
511145008852	nudix motif; other site
511145008853	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
511145008854	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
511145008855	dimer interface [polypeptide binding]; other site
511145008856	putative anticodon binding site; other site
511145008857	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
511145008858	motif 1; other site
511145008859	active site
511145008860	motif 2; other site
511145008861	motif 3; other site
511145008862	peptide chain release factor 2; Validated; Region: prfB; PRK00578
511145008863	This domain is found in peptide chain release factors; Region: PCRF; smart00937
511145008864	RF-1 domain; Region: RF-1; pfam00472
511145008865	ssDNA exonuclease RecJ; Provisional; Region: PRK11070
511145008866	DHH family; Region: DHH; pfam01368
511145008867	DHHA1 domain; Region: DHHA1; pfam02272
511145008868	protein disulfide isomerase II DsbC; Provisional; Region: PRK10877
511145008869	DsbA family, DsbC and DsbG subfamily; V-shaped homodimeric proteins containing a redox active CXXC motif imbedded in a TRX fold. They function as protein disulfide isomerases and chaperones in the bacterial periplasm to correct non-native disulfide bonds...; Region: DsbA_DsbC_DsbG; cd03020
511145008870	dimerization domain [polypeptide binding]; other site
511145008871	dimer interface [polypeptide binding]; other site
511145008872	catalytic residues [active]
511145008873	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
511145008874	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
511145008875	active site
511145008876	Int/Topo IB signature motif; other site
511145008877	flavodoxin FldB; Provisional; Region: PRK12359
511145008878	Protein of unknown function (DUF1434); Region: DUF1434; pfam07254
511145008879	hypothetical protein; Provisional; Region: PRK10878
511145008880	putative global regulator; Reviewed; Region: PRK09559
511145008881	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
511145008882	folate-binding protein YgfZ; Region: ygfZ_signature; TIGR03317
511145008883	hemolysin; Provisional; Region: PRK15087
511145008884	ASC-1 homology domain, subfamily similar to Escherichia coli Yqfb. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as...; Region: ASCH_yqfb_like; cd06552
511145008885	6-phospho-beta-glucosidase BglA; Provisional; Region: PRK15014
511145008886	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
511145008887	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
511145008888	classical (c) SDRs; Region: SDR_c; cd05233
511145008889	NAD(P) binding site [chemical binding]; other site
511145008890	active site
511145008891	glycine dehydrogenase; Provisional; Region: PRK05367
511145008892	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
511145008893	tetramer interface [polypeptide binding]; other site
511145008894	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145008895	catalytic residue [active]
511145008896	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
511145008897	tetramer interface [polypeptide binding]; other site
511145008898	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145008899	catalytic residue [active]
511145008900	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
511145008901	lipoyl attachment site [posttranslational modification]; other site
511145008902	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
511145008903	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
511145008904	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
511145008905	oxidoreductase; Provisional; Region: PRK08013
511145008906	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
511145008907	2-octaprenyl-6-methoxyphenyl hydroxylase; Validated; Region: PRK05732
511145008908	Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; Region: Ubi-OHases; TIGR01988
511145008909	proline aminopeptidase P II; Provisional; Region: PRK10879
511145008910	Aminopeptidase P, N-terminal domain; Region: AMP_N; pfam05195
511145008911	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
511145008912	active site
511145008913	hypothetical protein; Reviewed; Region: PRK01736
511145008914	Z-ring-associated protein; Provisional; Region: PRK10972
511145008915	5-formyltetrahydrofolate cyclo-ligase family protein; Provisional; Region: PRK10333
511145008916	D-3-phosphoglycerate dehydrogenase; Provisional; Region: PRK11790
511145008917	Phosphoglycerate dehydrogenases, NAD-binding and catalytic domains; Region: PGDH_3; cd12176
511145008918	ligand binding site [chemical binding]; other site
511145008919	NAD binding site [chemical binding]; other site
511145008920	tetramer interface [polypeptide binding]; other site
511145008921	catalytic site [active]
511145008922	C-terminal ACT (regulatory) domain of D-3-Phosphoglycerate Dehydrogenase (3PGDH) found in fungi and bacteria; Region: ACT_3PGDH; cd04901
511145008923	L-serine binding site [chemical binding]; other site
511145008924	ACT domain interface; other site
511145008925	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
511145008926	tetramer (dimer of dimers) interface [polypeptide binding]; other site
511145008927	active site
511145008928	dimer interface [polypeptide binding]; other site
511145008929	chromosome replication initiation inhibitor protein; Validated; Region: PRK03635
511145008930	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145008931	The C-terminal substrate binding domain of LysR-type transcriptional regulator, ArgP (IciA), for arginine exporter (ArgO); contains the type 2 periplasmic binding fold; Region: PBP2_IciA_ArgP; cd08428
511145008932	putative dimerization interface [polypeptide binding]; other site
511145008933	methylmalonyl-CoA mutase; Reviewed; Region: PRK09426
511145008934	Coenzyme B12-dependent-methylmalonyl coenzyme A (CoA) mutase (MCM) family, Alpha subunit-like subfamily; contains proteins similar to the alpha subunit of Propionbacterium shermanni MCM, as well as human and E. coli MCM. Members of this subfamily contain...; Region: MM_CoA_mutase_alpha_like; cd03679
511145008935	active site
511145008936	substrate binding site [chemical binding]; other site
511145008937	coenzyme B12 binding site [chemical binding]; other site
511145008938	methylmalonyl CoA mutase B12 binding domain. This domain binds to B12 (adenosylcobamide), which initiates the conversion of succinyl CoA and methylmalonyl CoA by forming an adenosyl radical, which then undergoes a rearrangement exchanging a hydrogen atom...; Region: MM_CoA_mut_B12_BD; cd02071
511145008939	B12 binding site [chemical binding]; other site
511145008940	cobalt ligand [ion binding]; other site
511145008941	LAO/AO transport system ATPase; Region: lao; TIGR00750
511145008942	The function of this protein family is unkown. The protein sequences are similar to the ArgK protein in E. coli. ArgK protein is a membrane ATPase which is required for transporting arginine, ornithine and lysine into the cells by the arginine and...; Region: ArgK-like; cd03114
511145008943	Walker A; other site
511145008944	methylmalonyl-CoA decarboxylase; Provisional; Region: PRK11423
511145008945	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145008946	substrate binding site [chemical binding]; other site
511145008947	oxyanion hole (OAH) forming residues; other site
511145008948	trimer interface [polypeptide binding]; other site
511145008949	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
511145008950	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
511145008951	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
511145008952	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145008953	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145008954	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
511145008955	dimerization interface [polypeptide binding]; other site
511145008956	oxidative stress defense protein; Provisional; Region: PRK11087
511145008957	arginine exporter protein; Provisional; Region: PRK09304
511145008958	mechanosensitive channel MscS; Provisional; Region: PRK10334
511145008959	Conserved TM helix; Region: TM_helix; pfam05552
511145008960	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145008961	Class II Type A, Fructose-1,6-bisphosphate (FBP) aldolases. The enzyme catalyses the zinc-dependent, reversible aldol condensation of dihydroxyacetone phosphate with glyceraldehyde-3-phosphate to form fructose-1,6-bisphosphate. FBP aldolase is...; Region: FBP_aldolase_IIA; cd00946
511145008962	active site
511145008963	intersubunit interface [polypeptide binding]; other site
511145008964	zinc binding site [ion binding]; other site
511145008965	Na+ binding site [ion binding]; other site
511145008966	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
511145008967	substrate binding site [chemical binding]; other site
511145008968	hinge regions; other site
511145008969	ADP binding site [chemical binding]; other site
511145008970	catalytic site [active]
511145008971	erythrose 4-phosphate dehydrogenase; Provisional; Region: PRK13535
511145008972	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
511145008973	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
511145008974	nucleoside triphosphate hydrolase domain-containing protein; Reviewed; Region: PRK09270
511145008975	active site
511145008976	putative DNA-binding transcriptional regulator; Provisional; Region: PRK10022
511145008977	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
511145008978	putative active site [active]
511145008979	L-sorbose-1-phosphate reductase; Region: sorbose_phosphate_red; cd08238
511145008980	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145008981	putative NAD(P) binding site [chemical binding]; other site
511145008982	catalytic Zn binding site [ion binding]; other site
511145008983	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
511145008984	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
511145008985	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
511145008986	active site
511145008987	P-loop; other site
511145008988	phosphorylation site [posttranslational modification]
511145008989	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145008990	active site
511145008991	phosphorylation site [posttranslational modification]
511145008992	transketolase; Reviewed; Region: PRK12753
511145008993	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
511145008994	TPP-binding site [chemical binding]; other site
511145008995	dimer interface [polypeptide binding]; other site
511145008996	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
511145008997	PYR/PP interface [polypeptide binding]; other site
511145008998	dimer interface [polypeptide binding]; other site
511145008999	TPP binding site [chemical binding]; other site
511145009000	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
511145009001	Zn-dependent protease with chaperone function [Posttranslational modification, protein turnover, chaperones]; Region: HtpX; COG0501
511145009002	Agmatinase-like family includes proclavaminic acid amidinohydrolase; Region: Agmatinase_PAH; cd11592
511145009003	oligomer interface [polypeptide binding]; other site
511145009004	putative active site [active]
511145009005	Mn binding site [ion binding]; other site
511145009006	Arginine decarboxylase (spermidine biosynthesis) [Amino acid transport and metabolism]; Region: SpeA; COG1166
511145009007	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Arginine Decarboxylase; Region: PLPDE_III_ADC; cd06830
511145009008	dimer interface [polypeptide binding]; other site
511145009009	active site
511145009010	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145009011	catalytic residues [active]
511145009012	substrate binding site [chemical binding]; other site
511145009013	Virulence promoting factor; Region: YqgB; pfam11036
511145009014	S-adenosylmethionine synthetase; Validated; Region: PRK05250
511145009015	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
511145009016	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
511145009017	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
511145009018	MFS transporter, sugar porter (SP) family; Region: SP; TIGR00879
511145009019	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145009020	putative substrate translocation pore; other site
511145009021	hypothetical protein; Provisional; Region: PRK04860
511145009022	DNA-specific endonuclease I; Provisional; Region: PRK15137
511145009023	RNA methyltransferase, RsmE family; Region: TIGR00046
511145009024	glutathione synthetase; Provisional; Region: PRK05246
511145009025	Prokaryotic glutathione synthetase, N-terminal domain; Region: GSH-S_N; pfam02951
511145009026	Prokaryotic glutathione synthetase, ATP-grasp domain; Region: GSH-S_ATP; pfam02955
511145009027	hypothetical protein; Validated; Region: PRK00228
511145009028	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
511145009029	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
511145009030	Walker A motif; other site
511145009031	ATP binding site [chemical binding]; other site
511145009032	Walker B motif; other site
511145009033	Pyridoxal 5-phosphate (PLP)-binding TIM barrel domain of Type III PLP-Dependent Enzymes, Yggs-like proteins; Region: PLPDE_III_Yggs_like; cd06824
511145009034	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145009035	catalytic residue [active]
511145009036	YGGT family; Region: YGGT; pfam02325
511145009037	Predicted integral membrane protein [Function unknown]; Region: COG0762
511145009038	hypothetical protein; Validated; Region: PRK05090
511145009039	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
511145009040	active site
511145009041	dimerization interface [polypeptide binding]; other site
511145009042	HemN family oxidoreductase; Provisional; Region: PRK05660
511145009043	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145009044	FeS/SAM binding site; other site
511145009045	HemN C-terminal domain; Region: HemN_C; pfam06969
511145009046	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
511145009047	Bacterial L-asparaginases and related enzymes; Region: L-asparaginase_like; cd00411
511145009048	active site
511145009049	homodimer interface [polypeptide binding]; other site
511145009050	hypothetical protein; Provisional; Region: PRK10626
511145009051	hypothetical protein; Provisional; Region: PRK11702
511145009052	Predicted S-adenosylmethionine-dependent methyltransferase [General function prediction only]; Region: COG0220
511145009053	adenine DNA glycosylase; Provisional; Region: PRK10880
511145009054	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
511145009055	minor groove reading motif; other site
511145009056	helix-hairpin-helix signature motif; other site
511145009057	substrate binding pocket [chemical binding]; other site
511145009058	active site
511145009059	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
511145009060	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
511145009061	DNA binding and oxoG recognition site [nucleotide binding]
511145009062	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2924
511145009063	murein transglycosylase C; Provisional; Region: mltC; PRK11671
511145009064	Domain of unknown function (DUF3393); Region: DUF3393; pfam11873
511145009065	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145009066	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145009067	catalytic residue [active]
511145009068	nucleoside transporter; Region: 2A0110; TIGR00889
511145009069	Nucleoside H+ symporter; Region: Nuc_H_symport; pfam03825
511145009070	ornithine decarboxylase; Provisional; Region: PRK13578
511145009071	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
511145009072	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
511145009073	homodimer interface [polypeptide binding]; other site
511145009074	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145009075	catalytic residue [active]
511145009076	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
511145009077	Uncharacterized membrane protein, possible Na+ channel or pump [General function prediction only]; Region: COG1811
511145009078	putative general secretion pathway protein YghD; Provisional; Region: PRK09731
511145009079	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
511145009080	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
511145009081	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
511145009082	Domain of unknown function (DUF4092); Region: DUF4092; pfam13322
511145009083	Peptidase M60-like family; Region: M60-like; pfam13402
511145009084	glycolate transporter; Provisional; Region: PRK09695
511145009085	Malate synthase G (MSG), monomeric enzyme present in some bacteria. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to malyl-CoA , which hydrolyzes to malate and CoA. This reaction is part of the glyoxylate...; Region: malate_synt_G; cd00728
511145009086	active site
511145009087	hypothetical protein; Provisional; Region: PRK09732
511145009088	glycolate oxidase iron-sulfur subunit; Provisional; Region: glcF; PRK11274
511145009089	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145009090	Cysteine-rich domain; Region: CCG; pfam02754
511145009091	Cysteine-rich domain; Region: CCG; pfam02754
511145009092	glycolate oxidase FAD binding subunit; Provisional; Region: glcE; PRK11282
511145009093	FAD binding domain; Region: FAD_binding_4; cl19922
511145009094	glycolate oxidase subunit GlcD; Provisional; Region: PRK11230
511145009095	FAD binding domain; Region: FAD_binding_4; pfam01565
511145009096	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
511145009097	DNA-binding transcriptional regulator GlcC; Provisional; Region: PRK09990
511145009098	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145009099	DNA-binding site [nucleotide binding]; DNA binding site
511145009100	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145009101	Transposase domain (DUF772); Region: DUF772; pfam05598
511145009102	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145009103	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145009104	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145009105	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
511145009106	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
511145009107	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
511145009108	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
511145009109	active site
511145009110	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
511145009111	TMP-binding site; other site
511145009112	ATP-binding site [chemical binding]; other site
511145009113	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
511145009114	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
511145009115	TMP-binding site; other site
511145009116	ATP-binding site [chemical binding]; other site
511145009117	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
511145009118	bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase; Provisional; Region: PRK10507
511145009119	CHAP domain; Region: CHAP; pfam05257
511145009120	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
511145009121	putative S-transferase; Provisional; Region: PRK11752
511145009122	GST_N family, Ure2p-like subfamily; composed of the Saccharomyces cerevisiae Ure2p and related GSTs. Ure2p is a regulator for nitrogen catabolism in yeast. It represses the expression of several gene products involved in the use of poor nitrogen sources...; Region: GST_N_Ure2p_like; cd03048
511145009123	C-terminal domain interface [polypeptide binding]; other site
511145009124	GSH binding site (G-site) [chemical binding]; other site
511145009125	dimer interface [polypeptide binding]; other site
511145009126	C-terminal, alpha helical domain of Escherichia coli Yghu Glutathione S-transferases and related uncharacterized proteins; Region: GST_C_YghU_like; cd10292
511145009127	dimer interface [polypeptide binding]; other site
511145009128	N-terminal domain interface [polypeptide binding]; other site
511145009129	active site
511145009130	hydrogenase 2 accessory protein HypG; Provisional; Region: PRK10413
511145009131	hydrogenase nickel incorporation protein HybF; Provisional; Region: PRK12380
511145009132	hydrogenase 2-specific chaperone; Provisional; Region: PRK10465
511145009133	coenzyme F420-reducing hydrogenase delta subunit (putative coenzyme F420 hydrogenase processing subunit); Region: frhD; TIGR00130
511145009134	Endopeptidases belonging to membrane-bound hydrogenases group. These hydrogenases transfer electrons from H2 to a cytochrome that is bound to a membrane-located complex coupling electron transfer to transmembrane proton translocation. Endopeptidase HybD...; Region: H2MP_MemB-H2up; cd06062
511145009135	putative substrate-binding site; other site
511145009136	nickel binding site [ion binding]; other site
511145009137	hydrogenase 2 large subunit; Provisional; Region: PRK10467
511145009138	putative hydrogenase 2 b cytochrome subunit; Provisional; Region: PRK10881
511145009139	hydrogenase 2 protein HybA; Provisional; Region: PRK10882
511145009140	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145009141	hydrogenase 2 small subunit; Provisional; Region: PRK10468
511145009142	Tat (twin-arginine translocation) pathway signal sequence; Region: TAT_signal_seq; TIGR01409
511145009143	NADH ubiquinone oxidoreductase, 20 Kd subunit; Region: Oxidored_q6; pfam01058
511145009144	NiFe/NiFeSe hydrogenase small subunit C-terminal; Region: NiFe_hyd_SSU_C; pfam14720
511145009145	Protein of unknown function (DUF2623); Region: DUF2623; pfam11115
511145009146	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145009147	voltage-dependent potassium channel beta subunit, animal; Region: Kv_beta; TIGR01293
511145009148	active site
511145009149	catalytic tetrad [active]
511145009150	hypothetical protein; Provisional; Region: PRK05208
511145009151	oxidoreductase; Provisional; Region: PRK07985
511145009152	classical (c) SDR, subgroup 1; Region: SDR_c1; cd05355
511145009153	NAD binding site [chemical binding]; other site
511145009154	metal binding site [ion binding]; metal-binding site
511145009155	active site
511145009156	biopolymer transport protein ExbD; Provisional; Region: PRK11267
511145009157	biopolymer transport protein ExbB; Provisional; Region: PRK10414
511145009158	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
511145009159	homodimer interface [polypeptide binding]; other site
511145009160	substrate-cofactor binding pocket; other site
511145009161	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145009162	catalytic residue [active]
511145009163	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
511145009164	AraC-type transcriptional regulator N-terminus; Region: AraC_N; pfam06719
511145009165	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
511145009166	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145009167	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145009168	Butanol dehydrogenase catalyzes the conversion of butyraldehyde to butanol with the cofactor NAD(P)H being oxidized in the process; Region: BDH; cd08187
511145009169	dimer interface [polypeptide binding]; other site
511145009170	active site
511145009171	metal binding site [ion binding]; metal-binding site
511145009172	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
511145009173	active site
511145009174	catalytic tetrad [active]
511145009175	Protein of unknown function (DUF3828); Region: DUF3828; pfam12883
511145009176	putative outer membrane lipoprotein; Provisional; Region: PRK09973
511145009177	hypothetical protein; Provisional; Region: PRK01254
511145009178	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
511145009179	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
511145009180	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
511145009181	FtsI repressor; Provisional; Region: PRK10883
511145009182	The first Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_1_CueO_FtsP; cd04232
511145009183	Domain 2 interface [polypeptide binding]; other site
511145009184	Domain 3 interface [polypeptide binding]; other site
511145009185	trinuclear Cu binding site [ion binding]; other site
511145009186	The second Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_2_CueO_FtsP; cd13867
511145009187	Domain 1 interface [polypeptide binding]; other site
511145009188	Domain 3 interface [polypeptide binding]; other site
511145009189	The third Cupredoxin domain of the multicopper oxidase CueO, the cell division protein FtsP, and similar proteins; Region: CuRO_3_CueO_FtsP; cd13890
511145009190	Domain 2 interface [polypeptide binding]; other site
511145009191	Domain 1 interface [polypeptide binding]; other site
511145009192	Type 1 (T1) Cu binding site [ion binding]; other site
511145009193	trinuclear Cu binding site [ion binding]; other site
511145009194	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
511145009195	putative acyl-acceptor binding pocket; other site
511145009196	DNA topoisomerase IV, A subunit, proteobacterial; Region: parC_Gneg; TIGR01062
511145009197	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
511145009198	CAP-like domain; other site
511145009199	active site
511145009200	primary dimer interface [polypeptide binding]; other site
511145009201	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
511145009202	putative ABC transporter periplasmic-binding protein; Provisional; Region: PRK09755
511145009203	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
511145009204	peptide binding site [polypeptide binding]; other site
511145009205	antitoxin MqsA for MqsR toxin; Region: MqsA; cd12870
511145009206	toxin interface [polypeptide binding]; other site
511145009207	putative zinc finger/helix-turn-helix protein, YgiT family; Region: CxxCG_CxxCG_HTH; TIGR03830
511145009208	Zn binding site [ion binding]; other site
511145009209	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145009210	non-specific DNA binding site [nucleotide binding]; other site
511145009211	salt bridge; other site
511145009212	sequence-specific DNA binding site [nucleotide binding]; other site
511145009213	Motility quorum-sensing regulator (MqsR); Region: MqsR; cd12869
511145009214	peptide binding site [polypeptide binding]; other site
511145009215	DNA gyrase inhibitor [DNA replication, recombination, and repair]; Region: COG3449
511145009216	TIGR00156 family protein; Region: TIGR00156
511145009217	DNA-binding transcriptional regulator QseB; Provisional; Region: PRK10336
511145009218	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145009219	active site
511145009220	phosphorylation site [posttranslational modification]
511145009221	intermolecular recognition site; other site
511145009222	dimerization interface [polypeptide binding]; other site
511145009223	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145009224	DNA binding site [nucleotide binding]
511145009225	sensor protein QseC; Provisional; Region: PRK10337
511145009226	HAMP domain; Region: HAMP; pfam00672
511145009227	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145009228	dimer interface [polypeptide binding]; other site
511145009229	phosphorylation site [posttranslational modification]
511145009230	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145009231	ATP binding site [chemical binding]; other site
511145009232	Mg2+ binding site [ion binding]; other site
511145009233	G-X-G motif; other site
511145009234	Putative NADPH-quinone reductase (modulator of drug activity B) [General function prediction only]; Region: MdaB; COG2249
511145009235	Uncharacterized conserved protein [Function unknown]; Region: COG1359
511145009236	DNA topoisomerase IV, B subunit, proteobacterial; Region: parE_Gneg; TIGR01055
511145009237	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145009238	ATP binding site [chemical binding]; other site
511145009239	Mg2+ binding site [ion binding]; other site
511145009240	G-X-G motif; other site
511145009241	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
511145009242	anchoring element; other site
511145009243	dimer interface [polypeptide binding]; other site
511145009244	ATP binding site [chemical binding]; other site
511145009245	Topoisomerase-primase domain. This is a nucleotidyl transferase/hydrolase domain found in type IA, type IIA and type IIB topoisomerases, bacterial DnaG-type primases, small primase-like proteins from bacteria and archaea, OLD family nucleases from...; Region: TOPRIM; cl00718
511145009246	active site
511145009247	metal binding site [ion binding]; metal-binding site
511145009248	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
511145009249	esterase YqiA; Provisional; Region: PRK11071
511145009250	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
511145009251	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
511145009252	Enterobacter aerogenes GpdQ and related proteins, metallophosphatase domain; Region: MPP_GpdQ; cd07402
511145009253	active site
511145009254	metal binding site [ion binding]; metal-binding site
511145009255	hexamer interface [polypeptide binding]; other site
511145009256	putative dehydrogenase; Provisional; Region: PRK11039
511145009257	ADP-ribose pyrophosphatase NudF; Provisional; Region: nudF; PRK10729
511145009258	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
511145009259	dimer interface [polypeptide binding]; other site
511145009260	ADP-ribose binding site [chemical binding]; other site
511145009261	active site
511145009262	nudix motif; other site
511145009263	metal binding site [ion binding]; metal-binding site
511145009264	outer membrane channel protein; Reviewed; Region: tolC; PRK09465
511145009265	Outer membrane efflux protein; Region: OEP; pfam02321
511145009266	Outer membrane efflux protein; Region: OEP; pfam02321
511145009267	hypothetical protein; Provisional; Region: PRK11653
511145009268	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
511145009269	The Class III extradiol dioxygenase, 4,5-DOPA Dioxygenase, catalyzes the incorporation of both atoms of molecular oxygen into 4,5-dihydroxy-phenylalanine; Region: 45_DOPA_Dioxygenase; cd07363
511145009270	putative active site [active]
511145009271	metal binding site [ion binding]; metal-binding site
511145009272	zinc transporter ZupT; Provisional; Region: PRK04201
511145009273	3,4-dihydroxy-2-butanone 4-phosphate synthase; Provisional; Region: ribB; PRK03353
511145009274	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2960
511145009275	putative fimbrial protein; Provisional; Region: PRK09733
511145009276	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145009277	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145009278	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145009279	HTH-like domain; Region: HTH_21; pfam13276
511145009280	Integrase core domain; Region: rve; pfam00665
511145009281	Integrase core domain; Region: rve_3; pfam13683
511145009282	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
511145009283	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145009284	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145009285	Fimbrial protein; Region: Fimbrial; pfam00419
511145009286	glycogen synthesis protein GlgS; Provisional; Region: PRK02922
511145009287	Protein of unknown function (DUF1449); Region: DUF1449; pfam07290
511145009288	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
511145009289	Flotillin or reggie family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_flotillin; cd03399
511145009290	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
511145009291	bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Provisional; Region: PRK11316
511145009292	RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer...; Region: RfaE_like; cd01172
511145009293	putative ribose interaction site [chemical binding]; other site
511145009294	putative ADP binding site [chemical binding]; other site
511145009295	rfaE bifunctional protein, domain II; Region: rfaE_dom_II; TIGR02199
511145009296	active site
511145009297	nucleotide binding site [chemical binding]; other site
511145009298	HIGH motif; other site
511145009299	KMSKS motif; other site
511145009300	bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Reviewed; Region: PRK11072
511145009301	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
511145009302	metal binding triad; other site
511145009303	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; pfam08335
511145009304	Nucleotidyltransferase (NT) domain of Escherichia coli adenylyltransferase (GlnE), Escherichia coli uridylyl transferase (GlnD), and similar proteins; Region: NT_GlnE_GlnD_like; cd05401
511145009305	metal binding triad; other site
511145009306	GlnD PII-uridylyltransferase; Region: GlnD_UR_UTase; cl19627
511145009307	Uncharacterized conserved protein [Function unknown]; Region: COG3025
511145009308	Uncharacterized subgroup of the CYTH-like superfamily having an associated CHAD domain; Region: CYTH-like_Pase_CHAD; cd07756
511145009309	putative active site [active]
511145009310	putative metal binding residues [ion binding]; other site
511145009311	signature motif; other site
511145009312	putative triphosphate binding site [ion binding]; other site
511145009313	CHAD domain; Region: CHAD; pfam05235
511145009314	SH3 domain-containing protein; Provisional; Region: PRK10884
511145009315	Protein of unknown function (DUF1202); Region: DUF1202; pfam06717
511145009316	Bacterial SH3 domain homologues; Region: SH3b; smart00287
511145009317	multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase; Reviewed; Region: cca; PRK10885
511145009318	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
511145009319	active site
511145009320	NTP binding site [chemical binding]; other site
511145009321	metal binding triad [ion binding]; metal-binding site
511145009322	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
511145009323	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145009324	Zn2+ binding site [ion binding]; other site
511145009325	Mg2+ binding site [ion binding]; other site
511145009326	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
511145009327	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
511145009328	homooctamer interface [polypeptide binding]; other site
511145009329	active site
511145009330	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
511145009331	transcriptional activator TtdR; Provisional; Region: PRK09801
511145009332	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145009333	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_9; cd08479
511145009334	putative effector binding pocket; other site
511145009335	putative dimerization interface [polypeptide binding]; other site
511145009336	tartrate dehydratase subunit alpha; Validated; Region: PRK08230
511145009337	L(+)-tartrate dehydratase subunit beta; Validated; Region: PRK08228
511145009338	Sodium:sulfate symporter transmembrane region; Region: Na_sulph_symp; pfam00939
511145009339	anion transporter; Region: dass; TIGR00785
511145009340	transmembrane helices; other site
511145009341	UGMP family protein; Validated; Region: PRK09604
511145009342	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145009343	nucleotide binding site [chemical binding]; other site
511145009344	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
511145009345	DNA primase; Validated; Region: dnaG; PRK05667
511145009346	CHC2 zinc finger; Region: zf-CHC2; pfam01807
511145009347	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
511145009348	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
511145009349	active site
511145009350	metal binding site [ion binding]; metal-binding site
511145009351	interdomain interaction site; other site
511145009352	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
511145009353	DNA primase DnaG DnaB-binding; Region: DnaG_DnaB_bind; pfam08278
511145009354	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
511145009355	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
511145009356	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
511145009357	Sigma-70, non-essential region; Region: Sigma70_ner; pfam04546
511145009358	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145009359	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
511145009360	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145009361	DNA binding residues [nucleotide binding]
511145009362	G:T/U mismatch specific DNA glcosylase (MUG); Region: UDG_F2_MUG; cd10028
511145009363	active site
511145009364	SUMO-1 interface [polypeptide binding]; other site
511145009365	Siderophore-interacting protein [Inorganic ion transport and metabolism]; Region: ViuB; COG2375
511145009366	Siderophore interacting proteins share the domain structure of the ferredoxin reductase like family. Siderophores are produced in various bacteria (and some plants) to extract iron from hosts. Binding constants are high, so iron can be pilfered from...; Region: siderophore_interacting; cd06193
511145009367	FAD binding pocket [chemical binding]; other site
511145009368	FAD binding motif [chemical binding]; other site
511145009369	phosphate binding motif [ion binding]; other site
511145009370	NAD binding pocket [chemical binding]; other site
511145009371	Predicted transcriptional regulators [Transcription]; Region: COG1695
511145009372	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145009373	PAS fold; Region: PAS_3; pfam08447
511145009374	putative active site [active]
511145009375	heme pocket [chemical binding]; other site
511145009376	HAMP domain; Region: HAMP; pfam00672
511145009377	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
511145009378	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
511145009379	dimer interface [polypeptide binding]; other site
511145009380	putative CheW interface [polypeptide binding]; other site
511145009381	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145009382	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145009383	inhibitor-cofactor binding pocket; inhibition site
511145009384	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145009385	catalytic residue [active]
511145009386	tRNA-binding-domain-containing CsaA-like proteins. CsaA is a molecular chaperone with export related activities. CsaA has a putative tRNA binding activity. The functional unit of CsaA is a homodimer and this domain acts as a dimerization domain; Region: tRNA_bind_CsaA; cd02798
511145009387	dimer interface [polypeptide binding]; other site
511145009388	putative tRNA-binding site [nucleotide binding]; other site
511145009389	DNA-binding transcriptional repressor EbgR; Provisional; Region: PRK10339
511145009390	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145009391	DNA binding site [nucleotide binding]
511145009392	domain linker motif; other site
511145009393	Ligand-binding domain of DNA transcription repressor GalR which is one of two regulatory proteins involved in galactose transport and metabolism; Region: PBP1_GalR; cd01544
511145009394	putative dimerization interface [polypeptide binding]; other site
511145009395	putative ligand binding site [chemical binding]; other site
511145009396	cryptic beta-D-galactosidase subunit alpha; Reviewed; Region: ebgA; PRK10340
511145009397	Glycosyl hydrolases family 2, sugar binding domain; Region: Glyco_hydro_2_N; pfam02837
511145009398	Glycosyl hydrolases family 2; Region: Glyco_hydro_2; pfam00703
511145009399	Glycosyl hydrolases family 2, TIM barrel domain; Region: Glyco_hydro_2_C; pfam02836
511145009400	Beta galactosidase small chain; Region: Bgal_small_N; pfam02929
511145009401	cryptic beta-D-galactosidase subunit beta; Reviewed; Region: ebgC; PRK10202
511145009402	inner membrane transporter YjeM; Provisional; Region: PRK15238
511145009403	alpha-glucosidase; Provisional; Region: PRK10137
511145009404	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
511145009405	2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli  is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the...; Region: DCR_FMN; cd02930
511145009406	active site
511145009407	FMN binding site [chemical binding]; other site
511145009408	2,4-decadienoyl-CoA binding site; other site
511145009409	catalytic residue [active]
511145009410	4Fe-4S cluster binding site [ion binding]; other site
511145009411	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145009412	Predicted transcription regulator containing HTH domain [Transcription]; Region: COG5499
511145009413	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145009414	non-specific DNA binding site [nucleotide binding]; other site
511145009415	salt bridge; other site
511145009416	sequence-specific DNA binding site [nucleotide binding]; other site
511145009417	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4680
511145009418	SAM-dependent 23S ribosomal RNA mG1835 methyltransferase; Provisional; Region: PRK15001
511145009419	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145009420	S-adenosylmethionine binding site [chemical binding]; other site
511145009421	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG1451
511145009422	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
511145009423	putative active site [active]
511145009424	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
511145009425	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145009426	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145009427	integral membrane protein, TerC family; Region: R_switched_Alx; TIGR03718
511145009428	serine/threonine transporter SstT; Provisional; Region: PRK13628
511145009429	Bacterial inner membrane protein; Region: Imp-YgjV; pfam10688
511145009430	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
511145009431	galactarate dehydratase; Region: galactar-dH20; TIGR03248
511145009432	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
511145009433	glucuronate isomerase; Reviewed; Region: PRK02925
511145009434	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145009435	D-galactonate transporter; Region: 2A0114; TIGR00893
511145009436	putative substrate translocation pore; other site
511145009437	DNA-binding transcriptional repressor ExuR; Provisional; Region: PRK11523
511145009438	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145009439	DNA-binding site [nucleotide binding]; DNA binding site
511145009440	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145009441	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
511145009442	EnvZ/OmpR regulon moderator; Provisional; Region: PRK10629
511145009443	Protein of unknown function (DUF1090); Region: DUF1090; pfam06476
511145009444	Uncharacterized conserved protein [Function unknown]; Region: ElaB; COG4575
511145009445	Predicted membrane protein [Function unknown]; Region: COG5393
511145009446	YqjK-like protein; Region: YqjK; pfam13997
511145009447	Predicted membrane protein [Function unknown]; Region: COG2259
511145009448	Predicted glutathione S-transferase [Posttranslational modification, protein turnover, chaperones]; Region: ECM4; COG0435
511145009449	Glutathione S-transferase, N-terminal domain; Region: GST_N_2; pfam13409
511145009450	C-terminal, alpha helical domain of Class Omega-like Glutathione S-transferases; Region: GST_C_Omega_like; cd03190
511145009451	putative dimer interface [polypeptide binding]; other site
511145009452	N-terminal domain interface [polypeptide binding]; other site
511145009453	putative substrate binding pocket (H-site) [chemical binding]; other site
511145009454	Predicted membrane protein [Function unknown]; Region: COG3152
511145009455	Predicted membrane protein [Function unknown]; Region: COG3152
511145009456	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145009457	putative DNA-binding transcriptional regulator; Provisional; Region: PRK11074
511145009458	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145009459	dimerization interface [polypeptide binding]; other site
511145009460	Pirin-related protein [General function prediction only]; Region: COG1741
511145009461	Pirin; Region: Pirin; pfam02678
511145009462	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
511145009463	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145009464	serine transporter; Region: stp; TIGR00814
511145009465	L-serine dehydratase TdcG; Provisional; Region: PRK15040
511145009466	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
511145009467	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
511145009468	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
511145009469	homotrimer interaction site [polypeptide binding]; other site
511145009470	putative active site [active]
511145009471	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
511145009472	Pyruvate formate lyase 1; Region: PFL1; cd01678
511145009473	coenzyme A binding site [chemical binding]; other site
511145009474	active site
511145009475	catalytic residues [active]
511145009476	glycine loop; other site
511145009477	propionate/acetate kinase; Provisional; Region: PRK12379
511145009478	threonine/serine transporter TdcC; Provisional; Region: PRK13629
511145009479	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145009480	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
511145009481	tetramer interface [polypeptide binding]; other site
511145009482	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145009483	catalytic residue [active]
511145009484	DNA-binding transcriptional activator TdcA; Provisional; Region: PRK10341
511145009485	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145009486	The C-terminal substrate binding domain of LysR-type transcriptional regulator TdcA, which is involved in the degradation of L-serine and L-threonine, contains the type 2 periplasmic binding fold; Region: PBP2_TdcA; cd08418
511145009487	putative substrate binding pocket [chemical binding]; other site
511145009488	putative dimerization interface [polypeptide binding]; other site
511145009489	DNA-binding transcriptional activator TdcR; Provisional; Region: PRK11424
511145009490	hypothetical protein; Provisional; Region: PRK09716
511145009491	glycerate kinase I; Provisional; Region: PRK10342
511145009492	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
511145009493	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
511145009494	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
511145009495	alpha-dehydro-beta-deoxy-D-glucarate aldolase; Provisional; Region: PRK10558
511145009496	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145009497	D-galactonate transporter; Region: 2A0114; TIGR00893
511145009498	putative substrate translocation pore; other site
511145009499	galactarate dehydratase; Region: galactar-dH20; TIGR03248
511145009500	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
511145009501	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
511145009502	putative regulator PrlF; Provisional; Region: PRK09974
511145009503	Toxin with endonuclease activity YhaV; Region: Toxin_YhaV; pfam11663
511145009504	DNA-binding transcriptional regulator AgaR; Provisional; Region: PRK09802
511145009505	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145009506	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145009507	tagatose 6-phosphate aldolase subunit KbaZ; Provisional; Region: PRK15458
511145009508	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
511145009509	active site
511145009510	phosphorylation site [posttranslational modification]
511145009511	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
511145009512	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
511145009513	dimer interface [polypeptide binding]; other site
511145009514	active site
511145009515	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
511145009516	putative active site [active]
511145009517	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cd00453
511145009518	active site
511145009519	intersubunit interface [polypeptide binding]; other site
511145009520	zinc binding site [ion binding]; other site
511145009521	Na+ binding site [ion binding]; other site
511145009522	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
511145009523	active site
511145009524	phosphorylation site [posttranslational modification]
511145009525	PTS system N-acetylgalactosamine-specific transporter subunit IIC; Provisional; Region: PRK09757
511145009526	PTS system N-acetylgalactosamine-specific transporter subunit IID; Provisional; Region: PRK09855
511145009527	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
511145009528	active site
511145009529	trimer interface [polypeptide binding]; other site
511145009530	allosteric site; other site
511145009531	active site lid [active]
511145009532	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145009533	P pilus assembly protein, chaperone PapD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimC; COG3121
511145009534	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145009535	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145009536	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
511145009537	PapC N-terminal domain; Region: PapC_N; pfam13954
511145009538	Outer membrane usher protein; Region: Usher; pfam00577
511145009539	PapC C-terminal domain; Region: PapC_C; pfam13953
511145009540	Fimbrial protein; Region: Fimbrial; cl01416
511145009541	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
511145009542	putative SAM binding site [chemical binding]; other site
511145009543	putative homodimer interface [polypeptide binding]; other site
511145009544	Putative lipoprotein [General function prediction only]; Region: LppC; COG3107
511145009545	Periplasmic binding component of lipoprotein LppC, an immunodominant antigen; Region: PBP1_YraM_LppC_lipoprotein_like; cd06339
511145009546	putative ligand binding site [chemical binding]; other site
511145009547	TIGR00252 family protein; Region: TIGR00252
511145009548	Phosphoheptose isomerase is a member of the SIS (Sugar ISomerase) superfamily. Phosphoheptose isomerase catalyzes the isomerization of sedoheptulose 7-phosphate into D-glycero-D-mannoheptose 7-phosphate. This is the first step of the biosynthesis of...; Region: SIS_GmhA; cd05006
511145009549	dimer interface [polypeptide binding]; other site
511145009550	active site
511145009551	outer membrane lipoprotein; Provisional; Region: PRK11023
511145009552	BON domain; Region: BON; pfam04972
511145009553	BON domain; Region: BON; pfam04972
511145009554	Predicted permease; Region: DUF318; pfam03773
511145009555	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
511145009556	NAD dependent epimerase/dehydratase family; Region: Epimerase; pfam01370
511145009557	NAD(P) binding site [chemical binding]; other site
511145009558	active site
511145009559	intracellular protease, PfpI family; Region: PfpI; TIGR01382
511145009560	A type 1 glutamine amidotransferase (GATase1)-like domain found in PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_like; cd03134
511145009561	proposed catalytic triad [active]
511145009562	conserved cys residue [active]
511145009563	hypothetical protein; Provisional; Region: PRK03467
511145009564	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
511145009565	GIY-YIG motif/motif A; other site
511145009566	putative active site [active]
511145009567	putative metal binding site [ion binding]; other site
511145009568	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
511145009569	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145009570	Coenzyme A binding pocket [chemical binding]; other site
511145009571	Putative lipid carrier protein [Lipid metabolism]; Region: COG3154
511145009572	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
511145009573	putative protease; Provisional; Region: PRK15447
511145009574	hypothetical protein; Provisional; Region: PRK10508
511145009575	tryptophan permease; Provisional; Region: PRK10483
511145009576	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145009577	ATP-dependent RNA helicase DeaD; Provisional; Region: PRK11634
511145009578	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
511145009579	ATP binding site [chemical binding]; other site
511145009580	Mg++ binding site [ion binding]; other site
511145009581	motif III; other site
511145009582	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145009583	nucleotide binding region [chemical binding]; other site
511145009584	ATP-binding site [chemical binding]; other site
511145009585	RNA recognition motif in Escherichia coli cold-shock DEAD box protein A (CsdA) and similar proteins; Region: RRM_EcCsdA_like; cd12499
511145009586	putative RNA binding site [nucleotide binding]; other site
511145009587	lipoprotein NlpI; Provisional; Region: PRK11189
511145009588	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145009589	binding surface
511145009590	TPR motif; other site
511145009591	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
511145009592	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
511145009593	RNase E interface [polypeptide binding]; other site
511145009594	trimer interface [polypeptide binding]; other site
511145009595	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
511145009596	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
511145009597	RNase E interface [polypeptide binding]; other site
511145009598	trimer interface [polypeptide binding]; other site
511145009599	active site
511145009600	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
511145009601	putative nucleic acid binding region [nucleotide binding]; other site
511145009602	G-X-X-G motif; other site
511145009603	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
511145009604	RNA binding site [nucleotide binding]; other site
511145009605	domain interface; other site
511145009606	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
511145009607	16S/18S rRNA binding site [nucleotide binding]; other site
511145009608	S13e-L30e interaction site [polypeptide binding]; other site
511145009609	25S rRNA binding site [nucleotide binding]; other site
511145009610	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK05033
511145009611	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
511145009612	RNA binding site [nucleotide binding]; other site
511145009613	active site
511145009614	Pseudouridine synthase II TruB, C-terminal; Region: TruB-C_2; pfam09157
511145009615	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
511145009616	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
511145009617	Bacterial translation initiation factor IF-2 associated region; Region: IF2_assoc; pfam08364
511145009618	Uncharacterized protein conserved in bacteria (DUF2058); Region: DUF2058; cl01201
511145009619	translation initiation factor IF-2; Validated; Region: infB; PRK05306
511145009620	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
511145009621	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
511145009622	G1 box; other site
511145009623	putative GEF interaction site [polypeptide binding]; other site
511145009624	GTP/Mg2+ binding site [chemical binding]; other site
511145009625	Switch I region; other site
511145009626	G2 box; other site
511145009627	G3 box; other site
511145009628	Switch II region; other site
511145009629	G4 box; other site
511145009630	G5 box; other site
511145009631	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
511145009632	Translation-initiation factor 2; Region: IF-2; pfam11987
511145009633	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
511145009634	transcription elongation factor NusA; Validated; Region: nusA; PRK09202
511145009635	NusA N-terminal domain; Region: NusA_N; pfam08529
511145009636	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
511145009637	RNA binding site [nucleotide binding]; other site
511145009638	homodimer interface [polypeptide binding]; other site
511145009639	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
511145009640	G-X-X-G motif; other site
511145009641	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
511145009642	G-X-X-G motif; other site
511145009643	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
511145009644	transcription termination factor NusA, C-terminal duplication; Region: nusA_Cterm_rpt; TIGR01954
511145009645	hypothetical protein; Provisional; Region: PRK14641
511145009646	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
511145009647	putative oligomer interface [polypeptide binding]; other site
511145009648	putative RNA binding site [nucleotide binding]; other site
511145009649	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
511145009650	ANP binding site [chemical binding]; other site
511145009651	Substrate Binding Site II [chemical binding]; other site
511145009652	Substrate Binding Site I [chemical binding]; other site
511145009653	Predicted membrane-associated, metal-dependent hydrolase [General function prediction only]; Region: COG2194
511145009654	Disulfide bond formation protein DsbB; Region: DsbB; cl00649
511145009655	Sulfatase; Region: Sulfatase; pfam00884
511145009656	Preprotein translocase SecG subunit; Region: SecG; pfam03840
511145009657	phosphoglucosamine mutase; Provisional; Region: glmM; PRK10887
511145009658	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
511145009659	active site
511145009660	substrate binding site [chemical binding]; other site
511145009661	metal binding site [ion binding]; metal-binding site
511145009662	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
511145009663	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
511145009664	substrate binding pocket [chemical binding]; other site
511145009665	dimer interface [polypeptide binding]; other site
511145009666	inhibitor binding site; inhibition site
511145009667	ATP-dependent metalloprotease; Reviewed; Region: hflB; PRK10733
511145009668	FtsH Extracellular; Region: FtsH_ext; pfam06480
511145009669	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145009670	Walker A motif; other site
511145009671	ATP binding site [chemical binding]; other site
511145009672	Walker B motif; other site
511145009673	arginine finger; other site
511145009674	Peptidase family M41; Region: Peptidase_M41; pfam01434
511145009675	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145009676	S-adenosylmethionine binding site [chemical binding]; other site
511145009677	RNA-binding protein YhbY; Provisional; Region: PRK10343
511145009678	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
511145009679	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
511145009680	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
511145009681	D-alanyl-D-alanine carboxypeptidase/endopeptidase; Provisional; Region: PRK11113
511145009682	D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) [Cell envelope biogenesis, outer membrane]; Region: DacB; COG2027
511145009683	GTPase CgtA; Reviewed; Region: obgE; PRK12298
511145009684	GTP1/OBG; Region: GTP1_OBG; pfam01018
511145009685	Obg GTPase; Region: Obg; cd01898
511145009686	G1 box; other site
511145009687	GTP/Mg2+ binding site [chemical binding]; other site
511145009688	Switch I region; other site
511145009689	G2 box; other site
511145009690	G3 box; other site
511145009691	Switch II region; other site
511145009692	G4 box; other site
511145009693	G5 box; other site
511145009694	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
511145009695	EamA-like transporter family; Region: EamA; pfam00892
511145009696	EamA-like transporter family; Region: EamA; pfam00892
511145009697	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
511145009698	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
511145009699	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
511145009700	substrate binding pocket [chemical binding]; other site
511145009701	chain length determination region; other site
511145009702	substrate-Mg2+ binding site; other site
511145009703	catalytic residues [active]
511145009704	aspartate-rich region 1; other site
511145009705	active site lid residues [active]
511145009706	aspartate-rich region 2; other site
511145009707	DNA-binding transcriptional regulator Nlp; Provisional; Region: PRK10344
511145009708	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
511145009709	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
511145009710	hinge; other site
511145009711	active site
511145009712	Predicted transcriptional regulator, BolA superfamily [Transcription]; Region: COG5007
511145009713	Predicted NTP binding protein (contains STAS domain) [General function prediction only]; Region: COG3113
511145009714	ABC transporter periplasmic binding protein MlaC; Provisional; Region: PRK15117
511145009715	ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: Ttg2C; COG1463
511145009716	mce related protein; Region: MCE; pfam02470
511145009717	conserved hypothetical integral membrane protein; Region: TIGR00056
511145009718	putative ABC transporter ATP-binding protein YrbF; Provisional; Region: PRK11831
511145009719	ATP-binding cassette transport system involved in resistant to organic solvents; Region: ABC_Org_Solvent_Resistant; cd03261
511145009720	Walker A/P-loop; other site
511145009721	ATP binding site [chemical binding]; other site
511145009722	Q-loop/lid; other site
511145009723	ABC transporter signature motif; other site
511145009724	Walker B; other site
511145009725	D-loop; other site
511145009726	H-loop/switch region; other site
511145009727	putative calcium/sodium:proton antiporter; Provisional; Region: PRK10734
511145009728	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
511145009729	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
511145009730	D-arabinose 5-phosphate isomerase; Provisional; Region: PRK10892
511145009731	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
511145009732	putative active site [active]
511145009733	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
511145009734	3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; Provisional; Region: PRK09484
511145009735	lipopolysaccharide exporter periplasmic protein; Provisional; Region: PRK10893
511145009736	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1934
511145009737	lipopolysaccharide transport periplasmic protein LptA; Provisional; Region: PRK10894
511145009738	lipopolysaccharide ABC transporter ATP-binding protein; Provisional; Region: PRK10895
511145009739	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
511145009740	Walker A/P-loop; other site
511145009741	ATP binding site [chemical binding]; other site
511145009742	Q-loop/lid; other site
511145009743	ABC transporter signature motif; other site
511145009744	Walker B; other site
511145009745	D-loop; other site
511145009746	H-loop/switch region; other site
511145009747	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
511145009748	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
511145009749	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
511145009750	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
511145009751	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
511145009752	30S subunit binding site; other site
511145009753	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145009754	active site
511145009755	phosphorylation site [posttranslational modification]
511145009756	P-loop ATPase protein family; Region: ATP_bind_2; pfam03668
511145009757	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
511145009758	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145009759	dimerization domain swap beta strand [polypeptide binding]; other site
511145009760	regulatory protein interface [polypeptide binding]; other site
511145009761	active site
511145009762	regulatory phosphorylation site [posttranslational modification]; other site
511145009763	hypothetical protein; Provisional; Region: PRK10345
511145009764	Serine/threonine protein kinase [General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair]; Region: SPS1; COG0515
511145009765	Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane]; Region: MrcB; COG0744
511145009766	monofunctional biosynthetic peptidoglycan transglycosylase; Provisional; Region: mtgA; PRK00056
511145009767	isoprenoid biosynthesis protein with amidotransferase-like domain; Provisional; Region: PRK11780
511145009768	Type 1 glutamine amidotransferase (GATase1)-like domain found in zebrafish ES1; Region: GATase1_ES1; cd03133
511145009769	conserved cys residue [active]
511145009770	aerobic respiration control sensor protein ArcB; Provisional; Region: PRK11091
511145009771	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145009772	putative active site [active]
511145009773	heme pocket [chemical binding]; other site
511145009774	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145009775	dimer interface [polypeptide binding]; other site
511145009776	phosphorylation site [posttranslational modification]
511145009777	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145009778	ATP binding site [chemical binding]; other site
511145009779	Mg2+ binding site [ion binding]; other site
511145009780	G-X-G motif; other site
511145009781	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145009782	active site
511145009783	phosphorylation site [posttranslational modification]
511145009784	intermolecular recognition site; other site
511145009785	dimerization interface [polypeptide binding]; other site
511145009786	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
511145009787	putative binding surface; other site
511145009788	active site
511145009789	radical SAM protein, TIGR01212 family; Region: TIGR01212
511145009790	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145009791	FeS/SAM binding site; other site
511145009792	glutamate synthase subunit alpha; Provisional; Region: gltB; PRK11750
511145009793	Glutamine amidotransferases class-II (Gn-AT), glutamate synthase (GltS)-type. GltS is a homodimer that synthesizes L-glutamate from 2-oxoglutarate and L-glutamine, an important step in ammonia assimilation in bacteria, cyanobacteria and plants. The...; Region: GltS; cd00713
511145009794	active site
511145009795	dimer interface [polypeptide binding]; other site
511145009796	Glutamate synthase central domain; Region: Glu_syn_central; pfam04898
511145009797	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
511145009798	active site
511145009799	FMN binding site [chemical binding]; other site
511145009800	substrate binding site [chemical binding]; other site
511145009801	3Fe-4S cluster binding site [ion binding]; other site
511145009802	gltb_C. This domain is found at the C-terminus of the large subunit (gltB) of glutamate synthase (GltS). GltS encodes a complex iron-sulfur flavoprotein that catalyzes the synthesis of L-glutamate from L-glutamine and 2-oxoglutarate. It requires the...; Region: gltB_C; cd00982
511145009803	domain interface; other site
511145009804	glutamate synthase small subunit family protein, proteobacterial; Region: gltD_gamma_fam; TIGR01318
511145009805	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
511145009806	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145009807	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145009808	Protein of unknown function (DUF1120); Region: DUF1120; pfam06551
511145009809	putative fimbrial chaperone protein; Provisional; Region: PRK09918
511145009810	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145009811	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145009812	putative fimbrial outer membrane usher protein; Provisional; Region: PRK15304
511145009813	PapC N-terminal domain; Region: PapC_N; pfam13954
511145009814	Outer membrane usher protein; Region: Usher; pfam00577
511145009815	PapC C-terminal domain; Region: PapC_C; pfam13953
511145009816	Transposase domain (DUF772); Region: DUF772; pfam05598
511145009817	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145009818	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145009819	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145009820	Protein of unknown function (DUF1120); Region: DUF1120; pfam06551
511145009821	Protein of unknown function (DUF1016); Region: DUF1016; pfam06250
511145009822	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
511145009823	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
511145009824	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145009825	nucleotide binding site [chemical binding]; other site
511145009826	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
511145009827	putative active site cavity [active]
511145009828	putative sialic acid transporter; Provisional; Region: PRK03893
511145009829	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145009830	putative substrate translocation pore; other site
511145009831	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
511145009832	inhibitor site; inhibition site
511145009833	active site
511145009834	dimer interface [polypeptide binding]; other site
511145009835	catalytic residue [active]
511145009836	transcriptional regulator NanR; Provisional; Region: PRK03837
511145009837	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145009838	DNA-binding site [nucleotide binding]; DNA binding site
511145009839	FCD domain; Region: FCD; pfam07729
511145009840	C4-dicarboxylate transporter [Energy production and conversion]; Region: DcuC; COG3069
511145009841	putative cryptic C4-dicarboxylate transporter DcuD; Provisional; Region: PRK09804
511145009842	Stringent starvation protein B [General function prediction only]; Region: SspB; COG2969
511145009843	stringent starvation protein A; Provisional; Region: sspA; PRK09481
511145009844	GST_N family, Stringent starvation protein A (SspA) subfamily; SspA is a RNA polymerase (RNAP)-associated protein required for the lytic development of phage P1 and for stationary phase-induced acid tolerance of E. coli. It is implicated in survival...; Region: GST_N_SspA; cd03059
511145009845	C-terminal domain interface [polypeptide binding]; other site
511145009846	putative GSH binding site (G-site) [chemical binding]; other site
511145009847	dimer interface [polypeptide binding]; other site
511145009848	C-terminal, alpha helical domain of Stringent starvation protein A; Region: GST_C_SspA; cd03186
511145009849	dimer interface [polypeptide binding]; other site
511145009850	N-terminal domain interface [polypeptide binding]; other site
511145009851	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
511145009852	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
511145009853	23S rRNA interface [nucleotide binding]; other site
511145009854	L3 interface [polypeptide binding]; other site
511145009855	Predicted ATPase [General function prediction only]; Region: COG1485
511145009856	hypothetical protein; Provisional; Region: PRK11677
511145009857	serine endoprotease; Provisional; Region: PRK10139
511145009858	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
511145009859	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
511145009860	protein binding site [polypeptide binding]; other site
511145009861	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
511145009862	serine endoprotease; Provisional; Region: PRK10898
511145009863	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
511145009864	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
511145009865	protein binding site [polypeptide binding]; other site
511145009866	malate dehydrogenase; Provisional; Region: PRK05086
511145009867	Glyoxysomal and mitochondrial malate dehydrogenases; Region: MDH_glyoxysomal_mitochondrial; cd01337
511145009868	NAD binding site [chemical binding]; other site
511145009869	dimerization interface [polypeptide binding]; other site
511145009870	Substrate binding site [chemical binding]; other site
511145009871	arginine repressor; Provisional; Region: PRK05066
511145009872	Arginine repressor, DNA binding domain; Region: Arg_repressor; pfam01316
511145009873	Arginine repressor, C-terminal domain; Region: Arg_repressor_C; pfam02863
511145009874	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145009875	Barstar is an intracellular inhibitor of barnase, an extracellular ribonuclease of Bacillus amyloliquefaciens. Barstar binds tightly to the barnase active site and sterically blocks it thus inhibiting its potentially lethal RNase activity inside the cell; Region: Barstar; cd05142
511145009876	RNAase interaction site [polypeptide binding]; other site
511145009877	p-hydroxybenzoic acid efflux subunit AaeB; Provisional; Region: PRK10631
511145009878	Fusaric acid resistance protein family; Region: FUSC; pfam04632
511145009879	p-hydroxybenzoic acid efflux subunit AaeA; Provisional; Region: PRK10559
511145009880	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145009881	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145009882	efflux system membrane protein; Provisional; Region: PRK11594
511145009883	transcriptional regulator; Provisional; Region: PRK10632
511145009884	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145009885	The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain; Region: PBP2_CrgA_like; cd08422
511145009886	putative effector binding pocket; other site
511145009887	dimerization interface [polypeptide binding]; other site
511145009888	protease TldD; Provisional; Region: tldD; PRK10735
511145009889	hypothetical protein; Provisional; Region: PRK10899
511145009890	Protein of unknown function; Region: DUF3971; pfam13116
511145009891	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145009892	ribonuclease G; Provisional; Region: PRK11712
511145009893	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
511145009894	homodimer interface [polypeptide binding]; other site
511145009895	oligonucleotide binding site [chemical binding]; other site
511145009896	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
511145009897	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
511145009898	active site
511145009899	dimer interface [polypeptide binding]; other site
511145009900	rod shape-determining protein MreD; Provisional; Region: PRK11060
511145009901	rod shape-determining protein MreC; Region: mreC; TIGR00219
511145009902	rod shape-determining protein MreB; Provisional; Region: PRK13927
511145009903	MreB and similar proteins; Region: MreB_like; cd10225
511145009904	nucleotide binding site [chemical binding]; other site
511145009905	Mg binding site [ion binding]; other site
511145009906	putative protofilament interaction site [polypeptide binding]; other site
511145009907	RodZ interaction site [polypeptide binding]; other site
511145009908	regulatory protein CsrD; Provisional; Region: PRK11059
511145009909	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
511145009910	metal binding site [ion binding]; metal-binding site
511145009911	active site
511145009912	I-site; other site
511145009913	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145009914	Yhdh putative quinone oxidoreductases; Region: MDR_yhdh; cd08288
511145009915	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
511145009916	NADP binding site [chemical binding]; other site
511145009917	dimer interface [polypeptide binding]; other site
511145009918	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
511145009919	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
511145009920	carboxyltransferase (CT) interaction site; other site
511145009921	biotinylation site [posttranslational modification]; other site
511145009922	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
511145009923	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
511145009924	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
511145009925	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
511145009926	hypothetical protein; Provisional; Region: PRK10633
511145009927	Na(+)/pantothenate cotransporters: PanF of Escherichia coli and related proteins; solute binding domain; Region: SLC5sbd_PanF; cd10327
511145009928	Na binding site [ion binding]; other site
511145009929	ribosomal protein L11 methyltransferase; Region: prmA; TIGR00406
511145009930	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145009931	S-adenosylmethionine binding site [chemical binding]; other site
511145009932	tRNA-dihydrouridine synthase B; Provisional; Region: PRK10415
511145009933	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
511145009934	FMN binding site [chemical binding]; other site
511145009935	active site
511145009936	catalytic residues [active]
511145009937	substrate binding site [chemical binding]; other site
511145009938	global DNA-binding transcriptional dual regulator Fis; Provisional; Region: fis; PRK00430
511145009939	putative methyltransferase; Provisional; Region: PRK11524
511145009940	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145009941	Protein of unknown function (DUF2556); Region: DUF2556; pfam10831
511145009942	DNA-binding transcriptional regulator EnvR; Provisional; Region: PRK09975
511145009943	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145009944	MAATS-type transcriptional repressor, C-terminal region; Region: TetR_C_2; pfam08361
511145009945	multidrug efflux system transporter AcrA; Provisional; Region: PRK15030
511145009946	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145009947	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145009948	The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; Region: 2A0602; TIGR00915
511145009949	MMPL family; Region: MMPL; cl14618
511145009950	MMPL family; Region: MMPL; cl14618
511145009951	Prokaryotic membrane lipoprotein lipid attachment site; Region: LPAM_1; pfam08139
511145009952	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: BatB; COG4597
511145009953	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
511145009954	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145009955	dimer interface [polypeptide binding]; other site
511145009956	conserved gate region; other site
511145009957	putative PBP binding loops; other site
511145009958	ABC-ATPase subunit interface; other site
511145009959	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
511145009960	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145009961	dimer interface [polypeptide binding]; other site
511145009962	conserved gate region; other site
511145009963	putative PBP binding loops; other site
511145009964	ABC-ATPase subunit interface; other site
511145009965	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
511145009966	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
511145009967	Walker A/P-loop; other site
511145009968	ATP binding site [chemical binding]; other site
511145009969	Q-loop/lid; other site
511145009970	ABC transporter signature motif; other site
511145009971	Walker B; other site
511145009972	D-loop; other site
511145009973	H-loop/switch region; other site
511145009974	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
511145009975	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
511145009976	trimer interface [polypeptide binding]; other site
511145009977	putative metal binding site [ion binding]; other site
511145009978	Protein of unknown function (DUF1488); Region: DUF1488; pfam07369
511145009979	shikimate 5-dehydrogenase; Region: aroE; TIGR00507
511145009980	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
511145009981	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
511145009982	shikimate binding site; other site
511145009983	NAD(P) binding site [chemical binding]; other site
511145009984	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein; Provisional; Region: PRK10634
511145009985	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
511145009986	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
511145009987	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
511145009988	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
511145009989	hypothetical protein; Validated; Region: PRK03430
511145009990	hypothetical protein; Provisional; Region: PRK10736
511145009991	DNA protecting protein DprA; Region: dprA; TIGR00732
511145009992	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
511145009993	active site
511145009994	catalytic residues [active]
511145009995	metal binding site [ion binding]; metal-binding site
511145009996	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
511145009997	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
511145009998	putative active site [active]
511145009999	substrate binding site [chemical binding]; other site
511145010000	putative cosubstrate binding site; other site
511145010001	catalytic site [active]
511145010002	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
511145010003	substrate binding site [chemical binding]; other site
511145010004	N-terminal RNA binding domain of the methyltransferase Sun. The rRNA-specific 5-methylcytidine transferase Sun, also known as RrmB or Fmu shares the RNA-binding non-catalytic domain with the transcription termination factor NusB. The precise biological...; Region: Methyltransferase_Sun; cd00620
511145010005	putative RNA binding site [nucleotide binding]; other site
511145010006	16S rRNA methyltransferase B; Provisional; Region: PRK10901
511145010007	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145010008	S-adenosylmethionine binding site [chemical binding]; other site
511145010009	potassium transporter peripheral membrane component; Reviewed; Region: trkA; PRK09496
511145010010	TrkA-N domain; Region: TrkA_N; pfam02254
511145010011	TrkA-C domain; Region: TrkA_C; pfam02080
511145010012	TrkA-N domain; Region: TrkA_N; pfam02254
511145010013	TrkA-C domain; Region: TrkA_C; pfam02080
511145010014	large-conductance mechanosensitive channel; Reviewed; Region: mscL; PRK00567
511145010015	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3036
511145010016	zinc-responsive transcriptional regulator; Provisional; Region: zntR; PRK09514
511145010017	Helix-Turn-Helix DNA binding domain of Heavy Metal Resistance transcription regulators; Region: HTH_HMRTR; cd04770
511145010018	DNA binding residues [nucleotide binding]
511145010019	dimer interface [polypeptide binding]; other site
511145010020	metal binding site [ion binding]; metal-binding site
511145010021	hypothetical protein; Provisional; Region: PRK10203
511145010022	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
511145010023	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
511145010024	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
511145010025	alphaNTD homodimer interface [polypeptide binding]; other site
511145010026	alphaNTD - beta interaction site [polypeptide binding]; other site
511145010027	alphaNTD - beta' interaction site [polypeptide binding]; other site
511145010028	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
511145010029	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
511145010030	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
511145010031	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145010032	RNA binding surface [nucleotide binding]; other site
511145010033	30S ribosomal protein S11; Validated; Region: PRK05309
511145010034	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
511145010035	Ribosomal protein L36; Region: Ribosomal_L36; pfam00444
511145010036	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
511145010037	SecY translocase; Region: SecY; pfam00344
511145010038	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
511145010039	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
511145010040	23S rRNA binding site [nucleotide binding]; other site
511145010041	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
511145010042	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
511145010043	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
511145010044	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
511145010045	23S rRNA interface [nucleotide binding]; other site
511145010046	5S rRNA interface [nucleotide binding]; other site
511145010047	L27 interface [polypeptide binding]; other site
511145010048	L5 interface [polypeptide binding]; other site
511145010049	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
511145010050	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
511145010051	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
511145010052	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
511145010053	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
511145010054	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
511145010055	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
511145010056	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
511145010057	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
511145010058	RNA binding site [nucleotide binding]; other site
511145010059	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
511145010060	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
511145010061	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
511145010062	23S rRNA interface [nucleotide binding]; other site
511145010063	putative translocon interaction site; other site
511145010064	signal recognition particle (SRP54) interaction site; other site
511145010065	L23 interface [polypeptide binding]; other site
511145010066	trigger factor interaction site; other site
511145010067	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
511145010068	23S rRNA interface [nucleotide binding]; other site
511145010069	5S rRNA interface [nucleotide binding]; other site
511145010070	putative antibiotic binding site [chemical binding]; other site
511145010071	L25 interface [polypeptide binding]; other site
511145010072	L27 interface [polypeptide binding]; other site
511145010073	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
511145010074	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
511145010075	G-X-X-G motif; other site
511145010076	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
511145010077	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
511145010078	protein-rRNA interface [nucleotide binding]; other site
511145010079	putative translocon binding site; other site
511145010080	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
511145010081	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
511145010082	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
511145010083	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
511145010084	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
511145010085	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
511145010086	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
511145010087	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
511145010088	protein secretion protein GspB; Provisional; Region: PRK09697
511145010089	AAA domain; Region: AAA_22; pfam13401
511145010090	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
511145010091	Type II secretory pathway, component PulC [Intracellular trafficking and secretion]; Region: PulC; COG3031
511145010092	Type IV pilus biogenesis; Region: Pilus_PilP; pfam11356
511145010093	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
511145010094	type II secretion system protein D; Region: type_II_gspD; TIGR02517
511145010095	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
511145010096	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
511145010097	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
511145010098	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
511145010099	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
511145010100	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
511145010101	Walker A motif; other site
511145010102	ATP binding site [chemical binding]; other site
511145010103	Walker B motif; other site
511145010104	type II secretion system protein F; Region: GspF; TIGR02120
511145010105	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
511145010106	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
511145010107	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
511145010108	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
511145010109	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
511145010110	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
511145010111	Type II transport protein GspH; Region: GspH; pfam12019
511145010112	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
511145010113	type II secretion system protein I; Region: gspI; TIGR01707
511145010114	Type II secretion system (T2SS), protein I; Region: T2SI; pfam02501
511145010115	Type II secretory pathway, component PulJ [Intracellular trafficking and secretion]; Region: PulJ; COG4795
511145010116	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
511145010117	Type II secretion system (T2SS), protein J; Region: T2SJ; pfam11612
511145010118	Type II secretory pathway, component PulK [Intracellular trafficking and secretion]; Region: PulK; COG3156
511145010119	Type II secretion system (T2SS), protein K; Region: T2SK; pfam03934
511145010120	Type II secretory pathway, component PulL [Intracellular trafficking and secretion]; Region: PulL; COG3297
511145010121	Type II secretion system (T2SS), protein L; Region: T2SL; pfam05134
511145010122	GspL periplasmic domain; Region: GspL_C; pfam12693
511145010123	Type II secretion system (T2SS), protein M; Region: T2SM; pfam04612
511145010124	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
511145010125	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
511145010126	Bacterioferritin, ferritin-like diiron-binding domain; Region: Bacterioferritin; cd00907
511145010127	Ferritin-like domain; Region: Ferritin; pfam00210
511145010128	heme binding site [chemical binding]; other site
511145010129	ferroxidase pore; other site
511145010130	ferroxidase diiron center [ion binding]; other site
511145010131	bacterioferritin-associated ferredoxin; Provisional; Region: PRK10509
511145010132	Chitin-binding domain type 3; Region: ChtBD3; smart00495
511145010133	Chitin-binding domain type 3; Region: ChtBD3; smart00495
511145010134	Chitin-binding domain of chitinase C; Region: ChiC_BD; cd12215
511145010135	aromatic chitin/cellulose binding site residues [chemical binding]; other site
511145010136	PF-ChiA is an uncharacterized chitinase found in the hyperthermophilic archaeon Pyrococcus furiosus with a glycosyl hydrolase family 18 (GH18) catalytic domain as well as a cellulose-binding domain.  Members of this domain family are found not only in...; Region: GH18_PF-ChiA-like; cd06543
511145010137	active site
511145010138	Glycosyl hydrolases family 18; Region: Glyco_hydro_18; pfam00704
511145010139	elongation factor Tu; Reviewed; Region: PRK00049
511145010140	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
511145010141	G1 box; other site
511145010142	GEF interaction site [polypeptide binding]; other site
511145010143	GTP/Mg2+ binding site [chemical binding]; other site
511145010144	Switch I region; other site
511145010145	G2 box; other site
511145010146	G3 box; other site
511145010147	Switch II region; other site
511145010148	G4 box; other site
511145010149	G5 box; other site
511145010150	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
511145010151	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
511145010152	Antibiotic Binding Site [chemical binding]; other site
511145010153	elongation factor G; Reviewed; Region: PRK00007
511145010154	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
511145010155	G1 box; other site
511145010156	putative GEF interaction site [polypeptide binding]; other site
511145010157	GTP/Mg2+ binding site [chemical binding]; other site
511145010158	Switch I region; other site
511145010159	G2 box; other site
511145010160	G3 box; other site
511145010161	Switch II region; other site
511145010162	G4 box; other site
511145010163	G5 box; other site
511145010164	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
511145010165	Elongation Factor G, domain II; Region: EFG_II; pfam14492
511145010166	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
511145010167	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
511145010168	30S ribosomal protein S7; Validated; Region: PRK05302
511145010169	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
511145010170	S17 interaction site [polypeptide binding]; other site
511145010171	S8 interaction site; other site
511145010172	16S rRNA interaction site [nucleotide binding]; other site
511145010173	streptomycin interaction site [chemical binding]; other site
511145010174	23S rRNA interaction site [nucleotide binding]; other site
511145010175	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
511145010176	sulfur transfer complex subunit TusB; Provisional; Region: PRK13510
511145010177	sulfur relay protein TusC; Validated; Region: PRK00211
511145010178	sulfur transfer complex subunit TusD; Validated; Region: PRK00207
511145010179	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2964
511145010180	YheO-like PAS domain; Region: PAS_6; pfam08348
511145010181	HTH domain; Region: HTH_22; pfam13309
511145010182	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10902
511145010183	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
511145010184	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
511145010185	phi X174 lysis protein; Provisional; Region: PRK02793
511145010186	FKBP-type peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK10737
511145010187	FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Posttranslational modification, protein turnover, chaperones]; Region: SlpA; COG1047
511145010188	Predicted nucleic-acid-binding protein containing a Zn-ribbon domain [General function prediction only]; Region: COG3529
511145010189	glutathione-regulated potassium-efflux system protein KefB; Provisional; Region: PRK03659
511145010190	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; COG0475
511145010191	TrkA-N domain; Region: TrkA_N; pfam02254
511145010192	glutathione-regulated potassium-efflux system ancillary protein KefG; Provisional; Region: PRK04930
511145010193	putative ABC transporter ATP-binding protein; Provisional; Region: PRK10636
511145010194	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145010195	ABC transporter; Region: ABC_tran_2; pfam12848
511145010196	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145010197	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
511145010198	Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only]; Region: COG0429
511145010199	putative hydrolase; Provisional; Region: PRK10985
511145010200	hypothetical protein; Provisional; Region: PRK04966
511145010201	Phosphoribulokinase-like (PRK-like) is a family of proteins similar to phosphoribulokinase (PRK), the enzyme involved in the Benson-Calvin cycle in chloroplasts or photosynthetic prokaryotes. PRK catalyzes the phosphorylation of D-ribulose 5-phosphate to...; Region: PRK_like; cd02029
511145010202	active site
511145010203	hypothetical protein; Provisional; Region: PRK10738
511145010204	DNA-binding transcriptional dual regulator Crp; Provisional; Region: PRK11753
511145010205	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
511145010206	ligand binding site [chemical binding]; other site
511145010207	flexible hinge region; other site
511145010208	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
511145010209	putative switch regulator; other site
511145010210	non-specific DNA interactions [nucleotide binding]; other site
511145010211	DNA binding site [nucleotide binding]
511145010212	sequence specific DNA binding site [nucleotide binding]; other site
511145010213	putative cAMP binding site [chemical binding]; other site
511145010214	integral membrane protein, YccS/YhfK family; Region: YCCS_YHJK; TIGR01667
511145010215	FUSC-like inner membrane protein yccS; Region: FUSC-like; pfam12805
511145010216	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
511145010217	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
511145010218	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
511145010219	inhibitor-cofactor binding pocket; inhibition site
511145010220	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145010221	catalytic residue [active]
511145010222	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
511145010223	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
511145010224	glutamine binding [chemical binding]; other site
511145010225	catalytic triad [active]
511145010226	cell filamentation protein Fic; Provisional; Region: PRK10347
511145010227	Protein of unknown function (DUF2559); Region: DUF2559; pfam10832
511145010228	cyclophilin_EcCYP_like: cyclophilin-type A-like peptidylprolyl cis- trans isomerase (PPIase) domain similar to the cytosolic E. coli cyclophilin A and Streptomyces antibioticus SanCyp18. Compared to the archetypal cyclophilin Human cyclophilin A, these...; Region: cyclophilin_EcCYP_like; cd01920
511145010229	substrate binding site [chemical binding]; other site
511145010230	putative transporter; Provisional; Region: PRK03699
511145010231	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145010232	putative substrate translocation pore; other site
511145010233	nitrite reductase subunit NirD; Provisional; Region: PRK14989
511145010234	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145010235	BFD-like [2Fe-2S] binding domain; Region: Fer2_BFD; pfam04324
511145010236	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
511145010237	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
511145010238	Assimilatory nitrite reductase (NirD) family, Rieske domain; Assimilatory nitrate and nitrite reductases convert nitrate through nitrite to ammonium. Members include bacterial and fungal proteins. The bacterial NirD contains a single Rieske domain while...; Region: Rieske_NirD; cd03529
511145010239	nitrite transporter NirC; Provisional; Region: PRK11562
511145010240	siroheme synthase; Provisional; Region: cysG; PRK10637
511145010241	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
511145010242	Sirohaem biosynthesis protein central; Region: Sirohm_synth_M; pfam14824
511145010243	Sirohaem synthase dimerization region; Region: CysG_dimeriser; pfam10414
511145010244	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
511145010245	active site
511145010246	SAM binding site [chemical binding]; other site
511145010247	homodimer interface [polypeptide binding]; other site
511145010248	Protein of unknown function (DUF4223); Region: DUF4223; pfam13978
511145010249	putative fructoselysine transporter; Provisional; Region: frlA; PRK11357
511145010250	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145010251	fructoselysine-6-P-deglycase; Provisional; Region: frlB; PRK11382
511145010252	SIS domain. SIS (Sugar ISomerase) domains are found in many phosphosugar isomerases and phosphosugar binding proteins. SIS domains are also found in proteins that regulate the expression of genes involved in synthesis of phosphosugars; Region: SIS; cl00389
511145010253	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
511145010254	dimer interface [polypeptide binding]; other site
511145010255	active site
511145010256	fructoselysine 3-epimerase; Provisional; Region: PRK09856
511145010257	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
511145010258	Fructoselysine kinase-like.  Fructoselysine is a fructoseamine formed by glycation, a non-enzymatic reaction of glucose with a primary amine followed by an Amadori rearrangement, resulting in a protein that is modified at the amino terminus and at the...; Region: Fructoselysine_kinase_like; cd01940
511145010259	substrate binding site [chemical binding]; other site
511145010260	ATP binding site [chemical binding]; other site
511145010261	DNA-binding transcriptional regulator FrlR; Provisional; Region: PRK11402
511145010262	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145010263	DNA-binding site [nucleotide binding]; DNA binding site
511145010264	UTRA domain; Region: UTRA; pfam07702
511145010265	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
511145010266	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145010267	catalytic residue [active]
511145010268	Protein of unknown function; Region: YhfT; pfam10797
511145010269	Protein of unknown function DUF2620; Region: DUF2620; pfam10941
511145010270	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
511145010271	Phosphotriesterase (PTE) catalyzes the hydrolysis of organophosphate nerve agents, including the chemical warfare agents VX, soman, and sarin as well as the insecticide paraoxon. PTE exists as a homodimer with one active site per monomer. The active site...; Region: PTE; cd00530
511145010272	active site
511145010273	substrate binding pocket [chemical binding]; other site
511145010274	homodimer interaction site [polypeptide binding]; other site
511145010275	putative mutase; Provisional; Region: PRK12383
511145010276	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme yhfX; Region: PLPDE_III_yhfX_like; cd06811
511145010277	dimer interface [polypeptide binding]; other site
511145010278	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
511145010279	active site
511145010280	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145010281	substrate binding site [chemical binding]; other site
511145010282	catalytic residue [active]
511145010283	PRD domain protein EF_0829/AHA_3910; Region: EF_0829; TIGR03582
511145010284	Helix-turn-helix domain; Region: HTH_41; pfam14502
511145010285	YhfZ C-terminal domain; Region: YhfZ_C; pfam14503
511145010286	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
511145010287	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
511145010288	active site
511145010289	HIGH motif; other site
511145010290	dimer interface [polypeptide binding]; other site
511145010291	KMSKS motif; other site
511145010292	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145010293	phosphoglycolate phosphatase; Provisional; Region: PRK13222
511145010294	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145010295	motif II; other site
511145010296	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
511145010297	substrate binding site [chemical binding]; other site
511145010298	hexamer interface [polypeptide binding]; other site
511145010299	metal binding site [ion binding]; metal-binding site
511145010300	DNA adenine methylase; Provisional; Region: PRK10904
511145010301	cell division protein DamX; Validated; Region: PRK10905
511145010302	Sporulation related domain; Region: SPOR; pfam05036
511145010303	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
511145010304	active site
511145010305	dimer interface [polypeptide binding]; other site
511145010306	metal binding site [ion binding]; metal-binding site
511145010307	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
511145010308	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
511145010309	ADP binding site [chemical binding]; other site
511145010310	magnesium binding site [ion binding]; other site
511145010311	putative shikimate binding site; other site
511145010312	outer membrane porin HofQ; Provisional; Region: hofQ; PRK10560
511145010313	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
511145010314	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
511145010315	Protein of unknown function (DUF2531); Region: DUF2531; pfam10748
511145010316	Tfp pilus assembly protein PilN [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilN; COG3166
511145010317	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
511145010318	penicillin-binding protein 1a; Provisional; Region: mrcA; PRK11636
511145010319	Transglycosylase; Region: Transgly; pfam00912
511145010320	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
511145010321	adenosine nucleotide hydrolase NudE; Provisional; Region: nudE; PRK11762
511145010322	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
511145010323	ADP-ribose binding site [chemical binding]; other site
511145010324	dimer interface [polypeptide binding]; other site
511145010325	active site
511145010326	nudix motif; other site
511145010327	metal binding site [ion binding]; metal-binding site
511145010328	Intracellular growth attenuator protein IgaA; Region: IgaA; pfam07095
511145010329	GMP/IMP nucleotidase; Provisional; Region: PRK14988
511145010330	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
511145010331	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145010332	motif II; other site
511145010333	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145010334	RNA binding surface [nucleotide binding]; other site
511145010335	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
511145010336	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
511145010337	dimerization interface [polypeptide binding]; other site
511145010338	domain crossover interface; other site
511145010339	redox-dependent activation switch; other site
511145010340	Domain of unknown function (DUF4153); Region: DUF4153; pfam13687
511145010341	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_ATP; cd00484
511145010342	active site
511145010343	substrate-binding site [chemical binding]; other site
511145010344	metal-binding site [ion binding]
511145010345	ATP binding site [chemical binding]; other site
511145010346	osmolarity sensor protein; Provisional; Region: envZ; PRK09467
511145010347	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145010348	dimerization interface [polypeptide binding]; other site
511145010349	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145010350	dimer interface [polypeptide binding]; other site
511145010351	phosphorylation site [posttranslational modification]
511145010352	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145010353	ATP binding site [chemical binding]; other site
511145010354	Mg2+ binding site [ion binding]; other site
511145010355	G-X-G motif; other site
511145010356	osmolarity response regulator; Provisional; Region: ompR; PRK09468
511145010357	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145010358	active site
511145010359	phosphorylation site [posttranslational modification]
511145010360	intermolecular recognition site; other site
511145010361	dimerization interface [polypeptide binding]; other site
511145010362	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145010363	DNA binding site [nucleotide binding]
511145010364	transcription elongation factor GreB; Reviewed; Region: greB; PRK01885
511145010365	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
511145010366	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
511145010367	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
511145010368	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
511145010369	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
511145010370	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
511145010371	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
511145010372	RNA binding site [nucleotide binding]; other site
511145010373	ferrous iron transport protein A; Reviewed; Region: feoA; PRK09555
511145010374	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
511145010375	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
511145010376	G1 box; other site
511145010377	GTP/Mg2+ binding site [chemical binding]; other site
511145010378	Switch I region; other site
511145010379	G2 box; other site
511145010380	G3 box; other site
511145010381	Switch II region; other site
511145010382	G4 box; other site
511145010383	G5 box; other site
511145010384	Nucleoside recognition; Region: Gate; pfam07670
511145010385	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
511145010386	Nucleoside recognition; Region: Gate; pfam07670
511145010387	ferrous iron transport protein FeoC; Provisional; Region: PRK15431
511145010388	putative transposase; Provisional; Region: PRK09857
511145010389	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
511145010390	carboxylesterase BioH; Provisional; Region: PRK10349
511145010391	Putative lysophospholipase; Region: Hydrolase_4; cl19140
511145010392	Putative lysophospholipase; Region: Hydrolase_4; cl19140
511145010393	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
511145010394	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145010395	active site
511145010396	Fe/S biogenesis protein NfuA; Provisional; Region: PRK11190
511145010397	Fe-S cluster assembly scaffold protein [Posttranslational modification, protein turnover, chaperones]; Region: sufA; COG0316
511145010398	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
511145010399	high-affinity gluconate transporter; Provisional; Region: PRK14984
511145010400	GntP family permease; Region: GntP_permease; pfam02447
511145010401	4-alpha-glucanotransferase; Provisional; Region: malQ; PRK11052
511145010402	4-alpha-glucanotransferase; Region: malQ; TIGR00217
511145010403	maltodextrin phosphorylase; Provisional; Region: PRK14985
511145010404	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
511145010405	homodimer interface [polypeptide binding]; other site
511145010406	active site pocket [active]
511145010407	transcriptional regulator MalT; Provisional; Region: PRK04841
511145010408	AAA ATPase domain; Region: AAA_16; pfam13191
511145010409	Cohesin loading factor; Region: Cohesin_load; pfam10345
511145010410	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145010411	DNA binding residues [nucleotide binding]
511145010412	dimerization interface [polypeptide binding]; other site
511145010413	RNA 3'-terminal-phosphate cyclase; Provisional; Region: PRK04204
511145010414	RNA 3' phosphate cyclase domain -  RNA phosphate cyclases are enzymes that catalyze the ATP-dependent conversion of 3'-phosphate at the end of RNA into 2', 3'-cyclic phosphodiester bond. The enzymes are conserved in eucaryotes; Region: RNA_Cyclase; cd00295
511145010415	putative active site [active]
511145010416	adenylation catalytic residue [active]
511145010417	Uncharacterized conserved protein [Function unknown]; Region: RtcB; COG1690
511145010418	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
511145010419	Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: RtcR; COG4650
511145010420	Regulator of RNA terminal phosphate cyclase; Region: RtcR; pfam06956
511145010421	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145010422	Walker A motif; other site
511145010423	ATP binding site [chemical binding]; other site
511145010424	Walker B motif; other site
511145010425	arginine finger; other site
511145010426	intramembrane serine protease GlpG; Provisional; Region: PRK10907
511145010427	Protein of unknown function (DUF3582); Region: DUF3582; pfam12122
511145010428	Membrane associated serine protease [Amino acid transport and metabolism]; Region: COG0705
511145010429	GlpE sulfurtransferase (ST) and homologs are members of the Rhodanese Homology Domain superfamily. Unlike other rhodanese sulfurtransferases, GlpE is a single domain protein but indications are that it functions as a dimer. The active site contains a...; Region: GlpE_ST; cd01444
511145010430	active site residue [active]
511145010431	glycerol-3-phosphate dehydrogenase; Reviewed; Region: glpD; PRK12266
511145010432	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GlpA; COG0578
511145010433	glycogen phosphorylase; Provisional; Region: PRK14986
511145010434	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
511145010435	homodimer interface [polypeptide binding]; other site
511145010436	active site pocket [active]
511145010437	glycogen synthase; Provisional; Region: glgA; PRK00654
511145010438	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
511145010439	ADP-binding pocket [chemical binding]; other site
511145010440	homodimer interface [polypeptide binding]; other site
511145010441	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK00725
511145010442	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
511145010443	ligand binding site; other site
511145010444	oligomer interface; other site
511145010445	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
511145010446	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
511145010447	dimer interface [polypeptide binding]; other site
511145010448	N-terminal domain interface [polypeptide binding]; other site
511145010449	sulfate 1 binding site; other site
511145010450	glycogen debranching enzyme; Provisional; Region: PRK03705
511145010451	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
511145010452	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
511145010453	active site
511145010454	catalytic site [active]
511145010455	glycogen branching enzyme; Provisional; Region: PRK05402
511145010456	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
511145010457	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
511145010458	active site
511145010459	catalytic site [active]
511145010460	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
511145010461	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK06598
511145010462	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
511145010463	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
511145010464	putative antibiotic transporter; Provisional; Region: PRK10739
511145010465	low affinity gluconate transporter; Provisional; Region: PRK10472
511145010466	GntP family permease; Region: GntP_permease; pfam02447
511145010467	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
511145010468	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
511145010469	ATP-binding site [chemical binding]; other site
511145010470	Gluconate-6-phosphate binding site [chemical binding]; other site
511145010471	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
511145010472	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145010473	DNA binding site [nucleotide binding]
511145010474	domain linker motif; other site
511145010475	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
511145010476	putative ligand binding site [chemical binding]; other site
511145010477	putative dimerization interface [polypeptide binding]; other site
511145010478	Pirin-related protein [General function prediction only]; Region: COG1741
511145010479	Pirin; Region: Pirin; pfam02678
511145010480	putative oxidoreductase; Provisional; Region: PRK10206
511145010481	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145010482	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145010483	Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis]; Region: RimL; COG1670
511145010484	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145010485	Coenzyme A binding pocket [chemical binding]; other site
511145010486	Type VI protein secretion system component Hcp (secreted cytotoxin) [Intracellular trafficking, secretion,    and vesicular transport]; Region: Hcp; COG3157
511145010487	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145010488	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145010489	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145010490	IS1 transposase; Region: DDE_Tnp_IS1; pfam03400
511145010491	Immunity protein 19; Region: Imm19; pfam15567
511145010492	gamma-glutamyltranspeptidase; Reviewed; Region: ggt; PRK09615
511145010493	hypothetical protein; Provisional; Region: PRK10350
511145010494	cytoplasmic glycerophosphodiester phosphodiesterase; Provisional; Region: ugpQ; PRK09454
511145010495	Glycerophosphodiester phosphodiesterase domain in Escherichia coli cytosolic glycerophosphodiester phosphodiesterase UgpQ and similar proteins; Region: GDPD_EcUgpQ_like; cd08562
511145010496	putative active site [active]
511145010497	catalytic site [active]
511145010498	putative metal binding site [ion binding]; other site
511145010499	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
511145010500	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
511145010501	Walker A/P-loop; other site
511145010502	ATP binding site [chemical binding]; other site
511145010503	Q-loop/lid; other site
511145010504	ABC transporter signature motif; other site
511145010505	Walker B; other site
511145010506	D-loop; other site
511145010507	H-loop/switch region; other site
511145010508	TOBE domain; Region: TOBE_2; pfam08402
511145010509	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
511145010510	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010511	dimer interface [polypeptide binding]; other site
511145010512	conserved gate region; other site
511145010513	putative PBP binding loops; other site
511145010514	ABC-ATPase subunit interface; other site
511145010515	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
511145010516	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010517	dimer interface [polypeptide binding]; other site
511145010518	conserved gate region; other site
511145010519	putative PBP binding loops; other site
511145010520	ABC-ATPase subunit interface; other site
511145010521	glycerol-3-phosphate transporter periplasmic binding protein; Provisional; Region: PRK10974
511145010522	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
511145010523	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livF; PRK11614
511145010524	ATP-binding cassette domain of branched-chain amino acid transporter; Region: ABC_TM1139_LivF_branched; cd03224
511145010525	Walker A/P-loop; other site
511145010526	ATP binding site [chemical binding]; other site
511145010527	Q-loop/lid; other site
511145010528	ABC transporter signature motif; other site
511145010529	Walker B; other site
511145010530	D-loop; other site
511145010531	H-loop/switch region; other site
511145010532	leucine/isoleucine/valine transporter ATP-binding subunit; Provisional; Region: livG; PRK11300
511145010533	ATP-binding cassette component of branched chain amino acids transport system; Region: ABC_Mj1267_LivG_branched; cd03219
511145010534	Walker A/P-loop; other site
511145010535	ATP binding site [chemical binding]; other site
511145010536	Q-loop/lid; other site
511145010537	ABC transporter signature motif; other site
511145010538	Walker B; other site
511145010539	D-loop; other site
511145010540	H-loop/switch region; other site
511145010541	leucine/isoleucine/valine transporter permease subunit; Provisional; Region: livM; PRK11301
511145010542	Domain of unknown function (DUF3382); Region: DUF3382; pfam11862
511145010543	Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivM_like; cd06581
511145010544	TM-ABC transporter signature motif; other site
511145010545	Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of...; Region: TM_PBP1_LivH_like; cd06582
511145010546	TM-ABC transporter signature motif; other site
511145010547	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
511145010548	dimerization interface [polypeptide binding]; other site
511145010549	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
511145010550	ligand binding site [chemical binding]; other site
511145010551	Acetyltransferase (GNAT) domain; Region: DUF3749; pfam12568
511145010552	Type I periplasmic ligand-binding domain of ABC (Atpase Binding Cassette)-type active transport systems that are involved in the transport of all three branched chain aliphatic amino acids (leucine, isoleucine and valine); Region: PBP1_ABC_LIVBP_like; cd06342
511145010553	dimerization interface [polypeptide binding]; other site
511145010554	Receptor family ligand binding region; Region: ANF_receptor; pfam01094
511145010555	ligand binding site [chemical binding]; other site
511145010556	RNA polymerase factor sigma-32; Reviewed; Region: PRK06596
511145010557	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145010558	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145010559	DNA binding residues [nucleotide binding]
511145010560	cell division ABC transporter subunit FtsX; Provisional; Region: ftsX; PRK11026
511145010561	putative protein insertion permease FtsX; Region: ftsX; TIGR00439
511145010562	cell division protein FtsE; Provisional; Region: PRK10908
511145010563	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145010564	Walker A/P-loop; other site
511145010565	ATP binding site [chemical binding]; other site
511145010566	Q-loop/lid; other site
511145010567	ABC transporter signature motif; other site
511145010568	Walker B; other site
511145010569	D-loop; other site
511145010570	H-loop/switch region; other site
511145010571	Mitochondria Localisation Sequence; Region: AIF-MLS; pfam14962
511145010572	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
511145010573	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
511145010574	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
511145010575	P loop; other site
511145010576	GTP binding site [chemical binding]; other site
511145010577	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145010578	S-adenosylmethionine binding site [chemical binding]; other site
511145010579	hypothetical protein; Provisional; Region: PRK10910
511145010580	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
511145010581	Predicted membrane protein [Function unknown]; Region: COG3714
511145010582	zinc/cadmium/mercury/lead-transporting ATPase; Provisional; Region: zntA; PRK11033
511145010583	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
511145010584	metal-binding site [ion binding]
511145010585	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
511145010586	Soluble P-type ATPase [General function prediction only]; Region: COG4087
511145010587	SirA (also known as UvrY,  and YhhP) belongs to a family of two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA.  A...; Region: SirA; cd03423
511145010588	CPxP  motif; other site
511145010589	hypothetical protein; Provisional; Region: PRK11212
511145010590	hypothetical protein; Provisional; Region: PRK11615
511145010591	major facilitator superfamily transporter; Provisional; Region: PRK05122
511145010592	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145010593	putative substrate translocation pore; other site
511145010594	Domain of unknown function DUF20; Region: UPF0118; cl00465
511145010595	holo-(acyl carrier protein) synthase 2; Provisional; Region: PRK10351
511145010596	4'-phosphopantetheinyl transferase superfamily; Region: ACPS; pfam01648
511145010597	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
511145010598	The substrate-binding component of an ABC-type nickel import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA; cd08489
511145010599	substrate binding site [chemical binding]; other site
511145010600	nickel transporter permease NikB; Provisional; Region: PRK10352
511145010601	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010602	dimer interface [polypeptide binding]; other site
511145010603	conserved gate region; other site
511145010604	putative PBP binding loops; other site
511145010605	ABC-ATPase subunit interface; other site
511145010606	nickel transporter permease NikC; Provisional; Region: nikC; PRK10417
511145010607	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010608	dimer interface [polypeptide binding]; other site
511145010609	conserved gate region; other site
511145010610	putative PBP binding loops; other site
511145010611	ABC-ATPase subunit interface; other site
511145010612	nickel transporter ATP-binding protein NikD; Provisional; Region: nikD; PRK10418
511145010613	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145010614	Walker A/P-loop; other site
511145010615	ATP binding site [chemical binding]; other site
511145010616	Q-loop/lid; other site
511145010617	ABC transporter signature motif; other site
511145010618	Walker B; other site
511145010619	D-loop; other site
511145010620	H-loop/switch region; other site
511145010621	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145010622	nickel transporter ATP-binding protein NikE; Provisional; Region: nikE; PRK10419
511145010623	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145010624	Walker A/P-loop; other site
511145010625	ATP binding site [chemical binding]; other site
511145010626	Q-loop/lid; other site
511145010627	ABC transporter signature motif; other site
511145010628	Walker B; other site
511145010629	D-loop; other site
511145010630	H-loop/switch region; other site
511145010631	nickel responsive regulator; Provisional; Region: PRK02967
511145010632	NikR C terminal nickel binding domain; Region: NikR_C; pfam08753
511145010633	PAAR motif; Region: PAAR_motif; cl15808
511145010634	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145010635	RHS Repeat; Region: RHS_repeat; pfam05593
511145010636	RHS Repeat; Region: RHS_repeat; pfam05593
511145010637	RHS Repeat; Region: RHS_repeat; pfam05593
511145010638	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145010639	RHS Repeat; Region: RHS_repeat; pfam05593
511145010640	RHS Repeat; Region: RHS_repeat; pfam05593
511145010641	RHS protein; Region: RHS; pfam03527
511145010642	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
511145010643	Domain of unknown function (DUF4329); Region: DUF4329; pfam14220
511145010644	NTF2 fold immunity protein; Region: Imm-NTF2-2; pfam15631
511145010645	DDE_Tnp_1-associated; Region: DDE_Tnp_1_assoc; pfam13808
511145010646	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145010647	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145010648	Transposase [DNA replication, recombination, and repair]; Region: COG5433
511145010649	Structural glycoprotein p40/gp41 conserved region; Region: Baculo_gp41; pfam04700
511145010650	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
511145010651	ABC-2 type transporter; Region: ABC2_membrane; pfam01061
511145010652	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
511145010653	ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only]; Region: COG1123
511145010654	Walker A/P-loop; other site
511145010655	ATP binding site [chemical binding]; other site
511145010656	Q-loop/lid; other site
511145010657	ABC transporter signature motif; other site
511145010658	Walker B; other site
511145010659	D-loop; other site
511145010660	H-loop/switch region; other site
511145010661	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145010662	Walker A/P-loop; other site
511145010663	ATP binding site [chemical binding]; other site
511145010664	Q-loop/lid; other site
511145010665	ABC transporter signature motif; other site
511145010666	Walker B; other site
511145010667	D-loop; other site
511145010668	H-loop/switch region; other site
511145010669	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
511145010670	ABC-2 family transporter protein; Region: ABC2_membrane_2; pfam12679
511145010671	putative efflux pump membrane fusion protein; Provisional; Region: PRK03598
511145010672	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145010673	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145010674	Domain of unknown function (DUF4049); Region: DUF4049; pfam13258
511145010675	Protein of unknown function (DUF2776); Region: DUF2776; pfam10951
511145010676	Predicted flavoproteins [General function prediction only]; Region: COG2081
511145010677	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145010678	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
511145010679	universal stress protein UspB; Provisional; Region: PRK04960
511145010680	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145010681	Ligand Binding Site [chemical binding]; other site
511145010682	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
511145010683	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145010684	putative substrate translocation pore; other site
511145010685	putative methyltransferase; Provisional; Region: PRK10742
511145010686	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145010687	S-adenosylmethionine binding site [chemical binding]; other site
511145010688	Zn-dependent oligopeptidases [Amino acid transport and metabolism]; Region: Dcp; COG0339
511145010689	Peptidase family M3 dipeptidyl carboxypeptidase (DCP); Region: M3A_DCP; cd06456
511145010690	active site
511145010691	Zn binding site [ion binding]; other site
511145010692	Protein involved in catabolism of external DNA [General function prediction only]; Region: ComJ; COG2961
511145010693	glutathione reductase; Validated; Region: PRK06116
511145010694	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145010695	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145010696	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
511145010697	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145010698	dimerization interface [polypeptide binding]; other site
511145010699	putative DNA binding site [nucleotide binding]; other site
511145010700	putative Zn2+ binding site [ion binding]; other site
511145010701	Anion permease ArsB.  These permeases have been shown to export arsenate and antimonite in eubacteria and archaea.  A typical ArsB permease contains 8-13 transmembrane helices and can function either independently as a chemiosmotic transporter or as a...; Region: ArsB_permease; cd01118
511145010702	Citrate transporter; Region: CitMHS; pfam03600
511145010703	transmembrane helices; other site
511145010704	Arsenate Reductase (ArsC) family, ArsC subfamily; arsenic reductases similar to that encoded by arsC on the R733 plasmid of Escherichia coli. E. coli ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], the first step in the...; Region: ArsC_ArsC; cd03034
511145010705	catalytic residues [active]
511145010706	Transposase domain (DUF772); Region: DUF772; pfam05598
511145010707	Transposase and inactivated derivatives, IS5 family [DNA replication, recombination, and repair]; Region: COG3039
511145010708	DDE superfamily endonuclease; Region: DDE_Tnp_4; cl17710
511145010709	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
511145010710	outer membrane lipoprotein, Slp family; Region: slp; TIGR00752
511145010711	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
511145010712	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145010713	DNA binding residues [nucleotide binding]
511145010714	dimerization interface [polypeptide binding]; other site
511145010715	putative Mg(2+) transport ATPase; Provisional; Region: PRK09977
511145010716	MgtC family; Region: MgtC; pfam02308
511145010717	acid-resistance protein; Provisional; Region: hdeB; PRK11566
511145010718	acid-resistance protein; Provisional; Region: PRK10208
511145010719	acid-resistance membrane protein; Provisional; Region: PRK10209
511145010720	Fructose/tagarose-bisphosphate aldolase class II. This family includes fructose-1,6-bisphosphate (FBP) and tagarose 1,6-bisphosphate (TBP) aldolases. FBP-aldolase is homodimeric and used in gluconeogenesis and glycolysis; the enzyme controls the...; Region: FTBP_aldolase_II; cl17181
511145010721	multidrug efflux system protein MdtE; Provisional; Region: PRK09859
511145010722	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145010723	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145010724	multidrug efflux system protein AcrB; Provisional; Region: PRK15127
511145010725	MMPL family; Region: MMPL; cl14618
511145010726	MMPL family; Region: MMPL; cl14618
511145010727	transcriptional regulator YdeO; Provisional; Region: PRK09940
511145010728	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010729	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010730	DNA-binding transcriptional regulator GadX; Provisional; Region: PRK09978
511145010731	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010732	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010733	DOPA decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to DOPA/tyrosine decarboxylase (DDC), histidine decarboxylase (HDC), and...; Region: DOPA_deC_like; cd06450
511145010734	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145010735	catalytic residue [active]
511145010736	Haem-binding domain; Region: Haem_bd; pfam14376
511145010737	Cytochrome c peroxidase [Inorganic ion transport and metabolism]; Region: MauG; COG1858
511145010738	Di-haem cytochrome c peroxidase; Region: CCP_MauG; pfam03150
511145010739	Neutral trehalase [Carbohydrate transport and metabolism]; Region: TreA; COG1626
511145010740	trehalase; Provisional; Region: treF; PRK13270
511145010741	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
511145010742	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145010743	DNA binding residues [nucleotide binding]
511145010744	dimerization interface [polypeptide binding]; other site
511145010745	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145010746	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145010747	The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold; Region: PBP2_CrgA_like_3; cd08472
511145010748	putative effector binding pocket; other site
511145010749	putative dimerization interface [polypeptide binding]; other site
511145010750	inner membrane protein YhjD; Region: TIGR00766
511145010751	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145010752	metabolite-proton symporter; Region: 2A0106; TIGR00883
511145010753	putative substrate translocation pore; other site
511145010754	Uncharacterized protein involved in outer membrane biogenesis [Cell envelope biogenesis, outer membrane]; Region: AsmA; COG2982
511145010755	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145010756	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145010757	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
511145010758	substrate binding site [chemical binding]; other site
511145010759	ATP binding site [chemical binding]; other site
511145010760	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
511145010761	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
511145010762	C4-dicarboxylate transporter DctA; Reviewed; Region: PRK01663
511145010763	putative diguanylate cyclase; Provisional; Region: PRK13561
511145010764	HAMP domain; Region: HAMP; pfam00672
511145010765	diguanylate cyclase; Region: GGDEF; smart00267
511145010766	metal binding site [ion binding]; metal-binding site
511145010767	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145010768	cellulose synthase subunit BcsC; Provisional; Region: PRK11447
511145010769	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145010770	binding surface
511145010771	TPR motif; other site
511145010772	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145010773	binding surface
511145010774	TPR motif; other site
511145010775	Cellulose synthase operon protein C C-terminus (BCSC_C); Region: BCSC_C; pfam05420
511145010776	endo-1,4-D-glucanase; Provisional; Region: PRK11097
511145010777	cellulose synthase regulator protein; Provisional; Region: PRK11114
511145010778	cellulose synthase catalytic subunit; Provisional; Region: bcsA; PRK11498
511145010779	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
511145010780	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
511145010781	DXD motif; other site
511145010782	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
511145010783	PilZ domain; Region: PilZ; pfam07238
511145010784	Protein of unknown function (DUF2629); Region: DUF2629; pfam10945
511145010785	cellulose biosynthesis protein BcsE; Provisional; Region: PRK15045
511145010786	celllulose biosynthesis operon protein BcsF/YhjT; Region: cellullose_BcsF; TIGR03493
511145010787	Protein of unknown function (DUF3260); Region: DUF3260; pfam11658
511145010788	Toxin Ldr, type I toxin-antitoxin system; Region: Ldr_toxin; pfam13940
511145010789	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145010790	serine transporter; Region: stp; TIGR00814
511145010791	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
511145010792	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145010793	Walker A/P-loop; other site
511145010794	ATP binding site [chemical binding]; other site
511145010795	Q-loop/lid; other site
511145010796	ABC transporter signature motif; other site
511145010797	Walker B; other site
511145010798	D-loop; other site
511145010799	H-loop/switch region; other site
511145010800	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145010801	dipeptide transporter ATP-binding subunit; Provisional; Region: dppD; PRK11022
511145010802	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145010803	Walker A/P-loop; other site
511145010804	ATP binding site [chemical binding]; other site
511145010805	Q-loop/lid; other site
511145010806	ABC transporter signature motif; other site
511145010807	Walker B; other site
511145010808	D-loop; other site
511145010809	H-loop/switch region; other site
511145010810	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145010811	dipeptide transporter; Provisional; Region: PRK10913
511145010812	N-terminal TM domain of oligopeptide transport permease C; Region: OppC_N; pfam12911
511145010813	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010814	dimer interface [polypeptide binding]; other site
511145010815	conserved gate region; other site
511145010816	putative PBP binding loops; other site
511145010817	ABC-ATPase subunit interface; other site
511145010818	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
511145010819	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145010820	dimer interface [polypeptide binding]; other site
511145010821	conserved gate region; other site
511145010822	putative PBP binding loops; other site
511145010823	ABC-ATPase subunit interface; other site
511145010824	antimicrobial peptide ABC transporter periplasmic binding protein SapA; Provisional; Region: PRK15109
511145010825	The substrate-binding component of an ABC-type dipeptide import system contains the type 2 periplasmic binding fold; Region: PBP2_DppA_like; cd08493
511145010826	peptide binding site [polypeptide binding]; other site
511145010827	phosphoethanolamine transferase; Provisional; Region: PRK11560
511145010828	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
511145010829	Sulfatase; Region: Sulfatase; pfam00884
511145010830	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
511145010831	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145010832	putative substrate translocation pore; other site
511145010833	Autotransporter protein or domain, integral membrane beta-barrel involved in protein secretion [Cell motility and secretion]; Region: COG5571
511145010834	3-methyl-adenine DNA glycosylase I; Provisional; Region: PRK10353
511145010835	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
511145010836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145010837	Coenzyme A binding pocket [chemical binding]; other site
511145010838	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
511145010839	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_DMSOR-BSOR-TMAOR; cd02769
511145010840	molybdopterin guanine dinucleotide-containing S/N-oxide reductases; Region: bisC_fam; TIGR00509
511145010841	molybdopterin cofactor binding site [chemical binding]; other site
511145010842	substrate binding site [chemical binding]; other site
511145010843	The MopB_DMSOR-BSOR-TMAOR CD contains dimethylsulfoxide reductase (DMSOR), biotin sulfoxide reductase (BSOR),  trimethylamine N-oxide reductase (TMAOR) and other related proteins. DMSOR always catalyzes the reduction of DMSO to dimethylsulfide, but its...; Region: MopB_CT_DMSOR-BSOR-TMAOR; cd02793
511145010844	molybdopterin cofactor binding site; other site
511145010845	putative outer membrane lipoprotein; Provisional; Region: PRK10510
511145010846	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
511145010847	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
511145010848	ligand binding site [chemical binding]; other site
511145010849	Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; Region: LdhA; COG1052
511145010850	D-glycerate dehydrogenase/hydroxypyruvate reductase (GDH); Region: GDH; cd05301
511145010851	dimerization interface [polypeptide binding]; other site
511145010852	ligand binding site [chemical binding]; other site
511145010853	NADP binding site [chemical binding]; other site
511145010854	catalytic site [active]
511145010855	Protein of unknown function (DUF3053); Region: DUF3053; pfam11254
511145010856	Predicted transcriptional regulator [Transcription]; Region: COG2944
511145010857	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145010858	non-specific DNA binding site [nucleotide binding]; other site
511145010859	salt bridge; other site
511145010860	sequence-specific DNA binding site [nucleotide binding]; other site
511145010861	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
511145010862	DNA-binding site [nucleotide binding]; DNA binding site
511145010863	RNA-binding motif; other site
511145010864	small toxic polypeptide; Provisional; Region: PRK09759
511145010865	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145010866	Helix-turn-helix domain; Region: HTH_28; pfam13518
511145010867	Helix-turn-helix domain; Region: HTH_28; pfam13518
511145010868	putative transposase OrfB; Reviewed; Region: PHA02517
511145010869	HTH-like domain; Region: HTH_21; pfam13276
511145010870	Integrase core domain; Region: rve; pfam00665
511145010871	Integrase core domain; Region: rve_2; pfam13333
511145010872	glycyl-tRNA synthetase, tetrameric type, beta subunit; Region: glyS; TIGR00211
511145010873	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
511145010874	DALR anticodon binding domain; Region: DALR_1; pfam05746
511145010875	anticodon binding site; other site
511145010876	tRNA binding surface [nucleotide binding]; other site
511145010877	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
511145010878	dimer interface [polypeptide binding]; other site
511145010879	motif 1; other site
511145010880	active site
511145010881	motif 2; other site
511145010882	motif 3; other site
511145010883	YsaB-like lipoprotein; Region: YsaB; pfam13983
511145010884	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
511145010885	hypothetical protein; Provisional; Region: PRK11383
511145010886	yiaA/B two helix domain; Region: YiaAB; pfam05360
511145010887	yiaA/B two helix domain; Region: YiaAB; pfam05360
511145010888	hypothetical protein; Provisional; Region: PRK11403
511145010889	yiaA/B two helix domain; Region: YiaAB; pfam05360
511145010890	xylulokinase; Provisional; Region: PRK15027
511145010891	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
511145010892	N- and C-terminal domain interface [polypeptide binding]; other site
511145010893	active site
511145010894	MgATP binding site [chemical binding]; other site
511145010895	catalytic site [active]
511145010896	metal binding site [ion binding]; metal-binding site
511145010897	xylulose binding site [chemical binding]; other site
511145010898	homodimer interface [polypeptide binding]; other site
511145010899	xylose isomerase; Provisional; Region: PRK05474
511145010900	ABC-type xylose transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: XylF; COG4213
511145010901	Periplasmic xylose-binding component of the ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_xylose_binding; cd01538
511145010902	putative ligand binding site [chemical binding]; other site
511145010903	xylose transporter ATP-binding subunit; Provisional; Region: PRK13549
511145010904	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145010905	Walker A/P-loop; other site
511145010906	ATP binding site [chemical binding]; other site
511145010907	Q-loop/lid; other site
511145010908	ABC transporter signature motif; other site
511145010909	Walker B; other site
511145010910	D-loop; other site
511145010911	H-loop/switch region; other site
511145010912	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145010913	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145010914	TM-ABC transporter signature motif; other site
511145010915	Ligand-binding domain of DNA transcription repressor specific for xylose (XylR); Region: PBP1_XylR; cd01543
511145010916	putative dimerization interface [polypeptide binding]; other site
511145010917	Transcriptional regulators [Transcription]; Region: PurR; COG1609
511145010918	putative ligand binding site [chemical binding]; other site
511145010919	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010920	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145010921	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145010922	hypothetical protein; Provisional; Region: PRK10356
511145010923	Lysozyme subfamily 2; Region: LYZ2; smart00047
511145010924	alpha-amylase; Reviewed; Region: malS; PRK09505
511145010925	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
511145010926	active site
511145010927	catalytic site [active]
511145010928	valine--pyruvate transaminase; Provisional; Region: avtA; PRK09440
511145010929	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145010930	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145010931	homodimer interface [polypeptide binding]; other site
511145010932	catalytic residue [active]
511145010933	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
511145010934	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145010935	Transcriptional regulator [Transcription]; Region: IclR; COG1414
511145010936	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145010937	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145010938	2,3-diketo-L-gulonate reductase; Provisional; Region: PRK13260
511145010939	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
511145010940	2,3-diketo-L-gulonate TRAP transporter small permease protein YiaM; Provisional; Region: PRK09877
511145010941	L-dehydroascorbate transporter large permease subunit; Provisional; Region: PRK15060
511145010942	DctM-like transporters; Region: DctM; pfam06808
511145010943	TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: DctP; COG1638
511145010944	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
511145010945	Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism]; Region: XylB; COG1070
511145010946	L-xylulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_L-XK; cd07802
511145010947	putative N- and C-terminal domain interface [polypeptide binding]; other site
511145010948	putative active site [active]
511145010949	MgATP binding site [chemical binding]; other site
511145010950	catalytic site [active]
511145010951	metal binding site [ion binding]; metal-binding site
511145010952	putative xylulose binding site [chemical binding]; other site
511145010953	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
511145010954	active site
511145010955	dimer interface [polypeptide binding]; other site
511145010956	magnesium binding site [ion binding]; other site
511145010957	putative L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13210
511145010958	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
511145010959	AP (apurinic/apyrimidinic) site pocket; other site
511145010960	DNA interaction; other site
511145010961	Metal-binding active site; metal-binding site
511145010962	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
511145010963	intersubunit interface [polypeptide binding]; other site
511145010964	active site
511145010965	Zn2+ binding site [ion binding]; other site
511145010966	Outer membrane protein V [Cell envelope biogenesis, outer membrane]; Region: OmpV; COG3713
511145010967	Transcriptional regulator [Transcription]; Region: LysR; COG0583
511145010968	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145010969	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145010970	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
511145010971	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145010972	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145010973	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
511145010974	FlxA-like protein; Region: FlxA; pfam14282
511145010975	Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II and Staphylococcus aureus AldA1 (SACOL0154)-like; Region: ALDH_ACDHII_AcoD-like; cd07559
511145010976	NAD(P) binding site [chemical binding]; other site
511145010977	catalytic residues [active]
511145010978	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
511145010979	dimer interface [polypeptide binding]; other site
511145010980	active site
511145010981	metal binding site [ion binding]; metal-binding site
511145010982	selenocysteinyl-tRNA-specific translation factor; Provisional; Region: PRK10512
511145010983	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
511145010984	G1 box; other site
511145010985	putative GEF interaction site [polypeptide binding]; other site
511145010986	GTP/Mg2+ binding site [chemical binding]; other site
511145010987	Switch I region; other site
511145010988	G2 box; other site
511145010989	G3 box; other site
511145010990	Switch II region; other site
511145010991	G4 box; other site
511145010992	G5 box; other site
511145010993	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
511145010994	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
511145010995	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
511145010996	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
511145010997	selenocysteine synthase; Provisional; Region: PRK04311
511145010998	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
511145010999	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
511145011000	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145011001	catalytic residue [active]
511145011002	putative glutathione S-transferase; Provisional; Region: PRK10357
511145011003	GST_N family, unknown subfamily 3; composed of uncharacterized bacterial proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of...; Region: GST_N_3; cd03049
511145011004	putative C-terminal domain interface [polypeptide binding]; other site
511145011005	putative GSH binding site (G-site) [chemical binding]; other site
511145011006	putative dimer interface [polypeptide binding]; other site
511145011007	C-terminal, alpha helical domain of an unknown subfamily 6 of Glutathione S-transferases; Region: GST_C_6; cd03205
511145011008	dimer interface [polypeptide binding]; other site
511145011009	N-terminal domain interface [polypeptide binding]; other site
511145011010	putative substrate binding pocket (H-site) [chemical binding]; other site
511145011011	PAAR motif; Region: PAAR_motif; cl15808
511145011012	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145011013	RHS Repeat; Region: RHS_repeat; pfam05593
511145011014	RHS Repeat; Region: RHS_repeat; pfam05593
511145011015	RHS Repeat; Region: RHS_repeat; pfam05593
511145011016	Rhs family protein [Cell envelope biogenesis, outer membrane]; Region: RhsA; COG3209
511145011017	RHS Repeat; Region: RHS_repeat; pfam05593
511145011018	RHS Repeat; Region: RHS_repeat; pfam05593
511145011019	RHS protein; Region: RHS; pfam03527
511145011020	RHS repeat-associated core domain; Region: Rhs_assc_core; TIGR03696
511145011021	Putative toxin 55; Region: Toxin_55; pfam15606
511145011022	putative lyase; Provisional; Region: PRK09687
511145011023	HEAT-like repeat; Region: HEAT_EZ; pfam13513
511145011024	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
511145011025	Multidrug resistance efflux pump [Defense mechanisms]; Region: EmrA; COG1566
511145011026	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145011027	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145011028	Protein of unknown function (DUF3302); Region: DUF3302; pfam11742
511145011029	PTS system mannitol-specific transporter subunit IICBA; Provisional; Region: PRK15083
511145011030	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
511145011031	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
511145011032	active site
511145011033	P-loop; other site
511145011034	phosphorylation site [posttranslational modification]
511145011035	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145011036	active site
511145011037	phosphorylation site [posttranslational modification]
511145011038	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
511145011039	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
511145011040	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
511145011041	mannitol repressor protein; Provisional; Region: mtlR; PRK11001
511145011042	hypothetical protein; Provisional; Region: PRK11020
511145011043	L-lactate permease; Provisional; Region: PRK10420
511145011044	DNA-binding transcriptional repressor LldR; Provisional; Region: PRK10421
511145011045	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145011046	DNA-binding site [nucleotide binding]; DNA binding site
511145011047	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145011048	L-lactate dehydrogenase; Provisional; Region: lldD; PRK11197
511145011049	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
511145011050	active site
511145011051	substrate binding site [chemical binding]; other site
511145011052	FMN binding site [chemical binding]; other site
511145011053	putative catalytic residues [active]
511145011054	putative rRNA methylase; Provisional; Region: PRK10358
511145011055	serine acetyltransferase; Provisional; Region: cysE; PRK11132
511145011056	Serine acetyltransferase, N-terminal; Region: SATase_N; smart00971
511145011057	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
511145011058	trimer interface [polypeptide binding]; other site
511145011059	active site
511145011060	substrate binding site [chemical binding]; other site
511145011061	CoA binding site [chemical binding]; other site
511145011062	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
511145011063	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
511145011064	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
511145011065	Preprotein translocase subunit SecB. SecB is a cytoplasmic component of the multisubunit membrane-bound enzyme termed Sec protein translocase, which is the main constituent of the General Secretory (type II) Pathway involved in translocation of nascent...; Region: Translocase_SecB; cd00557
511145011066	SecA binding site; other site
511145011067	Preprotein binding site; other site
511145011068	Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the...; Region: GRX_GRXb_1_3_like; cd03418
511145011069	GSH binding site [chemical binding]; other site
511145011070	catalytic residues [active]
511145011071	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
511145011072	active site residue [active]
511145011073	phosphoglyceromutase; Provisional; Region: PRK05434
511145011074	AmiB activator; Provisional; Region: PRK11637
511145011075	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
511145011076	HemX; Region: HemX; cl19375
511145011077	Peptidase family M23; Region: Peptidase_M23; pfam01551
511145011078	Putative catalytic domain of family 2 polysaccharide deacetylases (DACs) from bacteria; Region: CE4_DAC2; cd10936
511145011079	NodB motif; other site
511145011080	putative active site [active]
511145011081	putative catalytic site [active]
511145011082	Zn binding site [ion binding]; other site
511145011083	putative glycosyl transferase; Provisional; Region: PRK10073
511145011084	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
511145011085	active site
511145011086	L-threonine 3-dehydrogenase; Validated; Region: tdh; PRK05396
511145011087	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
511145011088	NAD(P) binding site [chemical binding]; other site
511145011089	8-amino-7-oxononanoate synthase; Region: bioF; TIGR00858
511145011090	KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS); Region: KBL_like; cd06454
511145011091	substrate-cofactor binding pocket; other site
511145011092	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145011093	catalytic residue [active]
511145011094	hypothetical protein; Provisional; Region: PRK11346
511145011095	ADP-L-glycero-D-mannoheptose 6-epimerase (GME), extended (e) SDRs; Region: ADP_GME_SDR_e; cd05248
511145011096	ADP-L-glycero-D-mannoheptose-6-epimerase; Provisional; Region: rfaD; PRK11150
511145011097	NADP binding site [chemical binding]; other site
511145011098	homopentamer interface [polypeptide binding]; other site
511145011099	substrate binding site [chemical binding]; other site
511145011100	active site
511145011101	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
511145011102	putative active site [active]
511145011103	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
511145011104	putative active site [active]
511145011105	Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane]; Region: RfaL; COG3307
511145011106	O-Antigen ligase; Region: Wzy_C; pfam04932
511145011107	ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaF; COG0859
511145011108	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK09822
511145011109	lipopolysaccharide core biosynthesis protein; Provisional; Region: PRK10359
511145011110	Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases [Cell envelope biogenesis, outer membrane]; Region: RfaJ; COG1442
511145011111	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
511145011112	Ligand binding site; other site
511145011113	metal-binding site
511145011114	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
511145011115	lipopolysaccharide 1,3-galactosyltransferase; Provisional; Region: PRK15171
511145011116	A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; Region: GT8_A4GalT_like; cd04194
511145011117	Ligand binding site; other site
511145011118	metal-binding site
511145011119	Glycosyl transferase family 8 C-terminal; Region: Glyco_transf_8C; pfam08437
511145011120	UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase; Provisional; Region: PRK09922
511145011121	This family is most closely related to the GT1 family of glycosyltransferases. WabH in Klebsiella pneumoniae has been shown to transfer a GlcNAc residue from UDP-GlcNAc onto the acceptor GalUA residue in the cellular outer core; Region: GT1_WabH_like; cd03811
511145011122	putative ADP-binding pocket [chemical binding]; other site
511145011123	lipopolysaccharide core heptose(I) kinase RfaP; Provisional; Region: PRK15123
511145011124	This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to...; Region: GT1_YqgM_like; cd03801
511145011125	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
511145011126	Lipopolysaccharide heptosyltransferase is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from...; Region: GT1_LPS_heptosyltransferase; cd03789
511145011127	putative active site [active]
511145011128	3-deoxy-D-manno-octulosonic-acid transferase; Reviewed; Region: PRK05749
511145011129	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
511145011130	Glycosyl transferases group 1; Region: Glycos_transf_1; cl19138
511145011131	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
511145011132	active site
511145011133	(T/H)XGH motif; other site
511145011134	formamidopyrimidine/5-formyluracil/ 5-hydroxymethyluracil DNA glycosylase; Validated; Region: PRK01103
511145011135	N-terminal domain of Escherichia coli Fpg1/MutM and related bacterial DNA glycosylases; Region: EcFpg-like_N; cd08966
511145011136	DNA binding site [nucleotide binding]
511145011137	catalytic residue [active]
511145011138	H2TH interface [polypeptide binding]; other site
511145011139	putative catalytic residues [active]
511145011140	turnover-facilitating residue; other site
511145011141	intercalation triad [nucleotide binding]; other site
511145011142	8OG recognition residue [nucleotide binding]; other site
511145011143	putative reading head residues; other site
511145011144	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
511145011145	Zinc finger found in FPG and IleRS; Region: zf-FPG_IleRS; pfam06827
511145011146	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
511145011147	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
511145011148	hypothetical protein; Reviewed; Region: PRK00024
511145011149	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
511145011150	MPN+ (JAMM) motif; other site
511145011151	Zinc-binding site [ion binding]; other site
511145011152	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
511145011153	Flavoprotein; Region: Flavoprotein; cl19190
511145011154	DNA / pantothenate metabolizm flavoprotein; Region: DFP; pfam04127
511145011155	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
511145011156	trimer interface [polypeptide binding]; other site
511145011157	active site
511145011158	division inhibitor protein; Provisional; Region: slmA; PRK09480
511145011159	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145011160	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
511145011161	active site
511145011162	hypothetical protein; Provisional; Region: PRK11820
511145011163	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
511145011164	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
511145011165	DNA-damage-inducible protein D; Provisional; Region: dinD; PRK11525
511145011166	BRO family, N-terminal domain; Region: Bro-N; pfam02498
511145011167	Predicted membrane protein [Function unknown]; Region: COG2860
511145011168	UPF0126 domain; Region: UPF0126; pfam03458
511145011169	UPF0126 domain; Region: UPF0126; pfam03458
511145011170	NAD-dependent DNA ligase LigB; Reviewed; Region: ligB; PRK08097
511145011171	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
511145011172	nucleotide binding pocket [chemical binding]; other site
511145011173	K-X-D-G motif; other site
511145011174	catalytic site [active]
511145011175	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
511145011176	Guanylate kinase; Region: Guanylate_kin; pfam00625
511145011177	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
511145011178	catalytic site [active]
511145011179	G-X2-G-X-G-K; other site
511145011180	DNA-directed RNA polymerase, omega subunit; Region: rpoZ; TIGR00690
511145011181	bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase; Provisional; Region: PRK11092
511145011182	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
511145011183	Zn2+ binding site [ion binding]; other site
511145011184	Mg2+ binding site [ion binding]; other site
511145011185	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
511145011186	synthetase active site [active]
511145011187	NTP binding site [chemical binding]; other site
511145011188	metal binding site [ion binding]; metal-binding site
511145011189	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
511145011190	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
511145011191	tRNA guanosine-2'-O-methyltransferase; Provisional; Region: PRK11081
511145011192	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
511145011193	SpoU, rRNA methylase, C-terminal; Region: SpoU_methylas_C; pfam12105
511145011194	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
511145011195	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
511145011196	generic binding surface II; other site
511145011197	ssDNA binding site; other site
511145011198	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145011199	ATP binding site [chemical binding]; other site
511145011200	putative Mg++ binding site [ion binding]; other site
511145011201	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145011202	nucleotide binding region [chemical binding]; other site
511145011203	ATP-binding site [chemical binding]; other site
511145011204	sodium--glutamate symport carrier (gltS); Region: gltS; TIGR00210
511145011205	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
511145011206	Sulfate transporter family; Region: Sulfate_transp; cl19250
511145011207	AsmA family; Region: AsmA; pfam05170
511145011208	Domain of Unknown Function (DUF748); Region: DUF748; pfam05359
511145011209	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145011210	putative alpha-glucosidase; Provisional; Region: PRK10658
511145011211	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
511145011212	YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a...; Region: GH31_xylosidase_YicI; cd06593
511145011213	active site
511145011214	homotrimer interface [polypeptide binding]; other site
511145011215	catalytic site [active]
511145011216	homohexamer (dimer of homotrimers) interface [polypeptide binding]; other site
511145011217	putative transporter; Provisional; Region: PRK11462
511145011218	Na+/melibiose symporter and related transporters [Carbohydrate transport and metabolism]; Region: MelB; COG2211
511145011219	sugar efflux transporter B; Provisional; Region: PRK15011
511145011220	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011221	putative substrate translocation pore; other site
511145011222	EamA-like transporter family; Region: EamA; pfam00892
511145011223	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
511145011224	EamA-like transporter family; Region: EamA; pfam00892
511145011225	cytoplasmic membrane lipoprotein-28; Provisional; Region: PRK09861
511145011226	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
511145011227	ribonucleoside transporter; Reviewed; Region: nepI; PRK10213
511145011228	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011229	putative substrate translocation pore; other site
511145011230	Protein of unknown function (DUF1198); Region: DUF1198; pfam06711
511145011231	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
511145011232	cryptic adenine deaminase; Provisional; Region: PRK10027
511145011233	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
511145011234	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
511145011235	active site
511145011236	sugar phosphate antiporter; Reviewed; Region: uhpT; PRK09556
511145011237	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011238	putative substrate translocation pore; other site
511145011239	regulatory protein UhpC; Provisional; Region: PRK11663
511145011240	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011241	putative substrate translocation pore; other site
511145011242	sensory histidine kinase UhpB; Provisional; Region: PRK11644
511145011243	MASE1; Region: MASE1; pfam05231
511145011244	Histidine kinase; Region: HisKA_3; pfam07730
511145011245	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145011246	ATP binding site [chemical binding]; other site
511145011247	Mg2+ binding site [ion binding]; other site
511145011248	G-X-G motif; other site
511145011249	DNA-binding transcriptional activator UhpA; Provisional; Region: PRK10360
511145011250	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145011251	active site
511145011252	phosphorylation site [posttranslational modification]
511145011253	intermolecular recognition site; other site
511145011254	dimerization interface [polypeptide binding]; other site
511145011255	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145011256	DNA binding residues [nucleotide binding]
511145011257	dimerization interface [polypeptide binding]; other site
511145011258	Acetolactate synthase, small (regulatory) subunit [Amino acid transport and metabolism]; Region: IlvH; COG0440
511145011259	N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS); Region: ACT_AHAS; cd04878
511145011260	putative valine binding site [chemical binding]; other site
511145011261	dimer interface [polypeptide binding]; other site
511145011262	acetolactate synthase catalytic subunit; Validated; Region: PRK08155
511145011263	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
511145011264	PYR/PP interface [polypeptide binding]; other site
511145011265	dimer interface [polypeptide binding]; other site
511145011266	TPP binding site [chemical binding]; other site
511145011267	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
511145011268	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
511145011269	TPP-binding site [chemical binding]; other site
511145011270	dimer interface [polypeptide binding]; other site
511145011271	ilvB operon leader peptide; Provisional; Region: PRK10214
511145011272	multidrug resistance protein D; Provisional; Region: emrD; PRK11652
511145011273	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011274	putative substrate translocation pore; other site
511145011275	Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only]; Region: AslB; COG0641
511145011276	Domain of unknown function (DUF202); Region: DUF202; pfam02656
511145011277	Predicted membrane protein [Function unknown]; Region: COG2149
511145011278	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
511145011279	Sulfatase; Region: Sulfatase; pfam00884
511145011280	uncharacterized SLC5 subfamily, Escherichia coli YidK-like; solute binding domain; Region: SLC5sbd_YidK; cd10328
511145011281	Na binding site [ion binding]; other site
511145011282	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
511145011283	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145011284	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145011285	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145011286	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
511145011287	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145011288	DNA-binding site [nucleotide binding]; DNA binding site
511145011289	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
511145011290	putative transporter; Validated; Region: PRK03818
511145011291	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
511145011292	TrkA-C domain; Region: TrkA_C; pfam02080
511145011293	TrkA-C domain; Region: TrkA_C; pfam02080
511145011294	AspT/YidE/YbjL antiporter duplication domain; Region: YidE_YbjL_dupl; TIGR01625
511145011295	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
511145011296	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
511145011297	putative dimer interface [polypeptide binding]; other site
511145011298	Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones]; Region: IbpA; COG0071
511145011299	Alpha-crystallin domain (ACD) found in Escherichia coli inclusion body-associated proteins IbpA and IbpB, and similar proteins.  IbpA and IbpB are 16 kDa small heat shock proteins (sHsps). sHsps are molecular chaperones that suppress protein aggregation...; Region: ACD_IbpA-B_like; cd06470
511145011300	putative dimer interface [polypeptide binding]; other site
511145011301	hypothetical protein; Provisional; Region: PRK11616
511145011302	Protein of unknown function (DUF3748); Region: DUF3748; pfam12566
511145011303	putative oxidoreductase; Provisional; Region: PRK11445
511145011304	geranylgeranyl reductase family; Region: GG-red-SF; TIGR02032
511145011305	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011306	D-galactonate transporter; Region: 2A0114; TIGR00893
511145011307	putative substrate translocation pore; other site
511145011308	galactonate dehydratase; Provisional; Region: PRK14017
511145011309	D-galactonate dehydratase catalyses the dehydration of galactonate to 2-keto-3-deoxygalactnate (KDGal), as part of the D-galactonate nonphosphorolytic catabolic Entner-Doudoroff pathway. D-galactonate dehydratase belongs to the enolase superfamily of...; Region: D-galactonate_dehydratase; cd03325
511145011310	putative active site pocket [active]
511145011311	putative metal binding site [ion binding]; other site
511145011312	Entner-Doudoroff aldolase; Region: eda; TIGR01182
511145011313	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
511145011314	active site
511145011315	intersubunit interface [polypeptide binding]; other site
511145011316	catalytic residue [active]
511145011317	2-keto-3-deoxy-galactonokinase [Carbohydrate transport and metabolism]; Region: DgoK; COG3734
511145011318	Transcriptional regulators [Transcription]; Region: FadR; COG2186
511145011319	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145011320	DNA-binding site [nucleotide binding]; DNA binding site
511145011321	FCD domain; Region: FCD; pfam07729
511145011322	hypothetical protein; Provisional; Region: PRK10215
511145011323	sugar phosphate phosphatase; Provisional; Region: PRK10513
511145011324	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145011325	active site
511145011326	motif I; other site
511145011327	motif II; other site
511145011328	hypothetical protein; Provisional; Region: PRK11426
511145011329	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
511145011330	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145011331	ATP binding site [chemical binding]; other site
511145011332	Mg2+ binding site [ion binding]; other site
511145011333	G-X-G motif; other site
511145011334	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
511145011335	anchoring element; other site
511145011336	dimer interface [polypeptide binding]; other site
511145011337	ATP binding site [chemical binding]; other site
511145011338	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
511145011339	active site
511145011340	putative metal-binding site [ion binding]; other site
511145011341	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
511145011342	recF protein; Region: recf; TIGR00611
511145011343	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145011344	Walker A/P-loop; other site
511145011345	ATP binding site [chemical binding]; other site
511145011346	Q-loop/lid; other site
511145011347	ABC transporter signature motif; other site
511145011348	Walker B; other site
511145011349	D-loop; other site
511145011350	H-loop/switch region; other site
511145011351	DNA polymerase III subunit beta; Validated; Region: PRK05643
511145011352	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
511145011353	putative DNA binding surface [nucleotide binding]; other site
511145011354	dimer interface [polypeptide binding]; other site
511145011355	beta-clamp/clamp loader binding surface; other site
511145011356	beta-clamp/translesion DNA polymerase binding surface; other site
511145011357	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
511145011358	DnaA N-terminal domain; Region: DnaA_N; pfam11638
511145011359	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
511145011360	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145011361	Walker A motif; other site
511145011362	ATP binding site [chemical binding]; other site
511145011363	Walker B motif; other site
511145011364	arginine finger; other site
511145011365	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
511145011366	DnaA box-binding interface [nucleotide binding]; other site
511145011367	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399
511145011368	ribonuclease P; Reviewed; Region: rnpA; PRK01732
511145011369	hypothetical protein; Validated; Region: PRK00041
511145011370	membrane protein insertase; Provisional; Region: PRK01318
511145011371	YidC periplasmic domain; Region: YidC_periplas; pfam14849
511145011372	Preprotein translocase subunit YidC [Intracellular trafficking and secretion]; Region: YidC; COG0706
511145011373	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
511145011374	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
511145011375	trmE is a tRNA modification GTPase; Region: trmE; cd04164
511145011376	G1 box; other site
511145011377	GTP/Mg2+ binding site [chemical binding]; other site
511145011378	Switch I region; other site
511145011379	G2 box; other site
511145011380	Switch II region; other site
511145011381	G3 box; other site
511145011382	G4 box; other site
511145011383	G5 box; other site
511145011384	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
511145011385	Tryptophanese operon leader peptide; Region: Tna_leader; pfam08053
511145011386	Tryptophanase [Amino acid transport and metabolism]; Region: TnaA; COG3033
511145011387	tryptophanase, leader peptide-associated; Region: tnaA_trp_ase; TIGR02617
511145011388	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
511145011389	catalytic residue [active]
511145011390	tryptophan permease TnaB; Provisional; Region: PRK09664
511145011391	Amino acid permeases [Amino acid transport and metabolism]; Region: SdaC; COG0814
511145011392	multidrug efflux system protein MdtL; Provisional; Region: PRK10473
511145011393	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011394	putative substrate translocation pore; other site
511145011395	DNA-binding transcriptional regulator YidZ; Provisional; Region: PRK10216
511145011396	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145011397	The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold; Region: PBP2_Nitroaromatics_like; cd08417
511145011398	substrate binding pocket [chemical binding]; other site
511145011399	dimerization interface [polypeptide binding]; other site
511145011400	Phosphopantetheinyl transferase [Coenzyme metabolism]; Region: Sfp; COG2091
511145011401	Predicted flavoprotein [General function prediction only]; Region: COG0431
511145011402	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
511145011403	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
511145011404	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145011405	active site
511145011406	motif I; other site
511145011407	motif II; other site
511145011408	putative inner membrane protein; Provisional; Region: PRK09823
511145011409	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3196
511145011410	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
511145011411	active site
511145011412	trimer interface [polypeptide binding]; other site
511145011413	allosteric site; other site
511145011414	active site lid [active]
511145011415	N-terminal Early set domain associated with the catalytic domain of putative esterases; Region: E_set_Esterase_like_N; cd11294
511145011416	Enterochelin esterase and related enzymes [Inorganic ion transport and metabolism]; Region: Fes; COG2382
511145011417	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
511145011418	Maltoporin periplasmic N-terminal extension; Region: Sugarporin_N; pfam11471
511145011419	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
511145011420	maltoporin; Provisional; Region: lamB; PRK09360
511145011421	trimer interface; other site
511145011422	sugar binding site [chemical binding]; other site
511145011423	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
511145011424	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
511145011425	PTS system beta-glucoside-specific transporter subunits IIABC; Provisional; Region: PRK09824
511145011426	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145011427	active site turn [active]
511145011428	phosphorylation site [posttranslational modification]
511145011429	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
511145011430	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cd00210
511145011431	HPr interaction site; other site
511145011432	glycerol kinase (GK) interaction site [polypeptide binding]; other site
511145011433	active site
511145011434	phosphorylation site [posttranslational modification]
511145011435	transcriptional antiterminator BglG; Provisional; Region: PRK09772
511145011436	CAT RNA binding domain; Region: CAT_RBD; pfam03123
511145011437	PRD domain; Region: PRD; pfam00874
511145011438	PRD domain; Region: PRD; pfam00874
511145011439	transcriptional regulator PhoU; Provisional; Region: PRK11115
511145011440	PhoU domain; Region: PhoU; pfam01895
511145011441	PhoU domain; Region: PhoU; pfam01895
511145011442	phosphate transporter ATP-binding protein; Provisional; Region: pstB; PRK10744
511145011443	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
511145011444	Walker A/P-loop; other site
511145011445	ATP binding site [chemical binding]; other site
511145011446	Q-loop/lid; other site
511145011447	ABC transporter signature motif; other site
511145011448	Walker B; other site
511145011449	D-loop; other site
511145011450	H-loop/switch region; other site
511145011451	phosphate transporter permease subunit PtsA; Provisional; Region: pstA; PRK11268
511145011452	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145011453	dimer interface [polypeptide binding]; other site
511145011454	conserved gate region; other site
511145011455	putative PBP binding loops; other site
511145011456	ABC-ATPase subunit interface; other site
511145011457	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
511145011458	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145011459	dimer interface [polypeptide binding]; other site
511145011460	conserved gate region; other site
511145011461	putative PBP binding loops; other site
511145011462	ABC-ATPase subunit interface; other site
511145011463	phosphate ABC transporter periplasmic substrate-binding protein PstS; Provisional; Region: PRK10918
511145011464	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145011465	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
511145011466	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
511145011467	glutaminase active site [active]
511145011468	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
511145011469	dimer interface [polypeptide binding]; other site
511145011470	active site
511145011471	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
511145011472	dimer interface [polypeptide binding]; other site
511145011473	active site
511145011474	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK09451
511145011475	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
511145011476	Substrate binding site; other site
511145011477	Mg++ binding site; other site
511145011478	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
511145011479	active site
511145011480	substrate binding site [chemical binding]; other site
511145011481	CoA binding site [chemical binding]; other site
511145011482	F0F1 ATP synthase subunit epsilon; Validated; Region: atpC; PRK00571
511145011483	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
511145011484	gamma subunit interface [polypeptide binding]; other site
511145011485	epsilon subunit interface [polypeptide binding]; other site
511145011486	LBP interface [polypeptide binding]; other site
511145011487	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
511145011488	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
511145011489	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
511145011490	alpha subunit interaction interface [polypeptide binding]; other site
511145011491	Walker A motif; other site
511145011492	ATP binding site [chemical binding]; other site
511145011493	Walker B motif; other site
511145011494	inhibitor binding site; inhibition site
511145011495	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
511145011496	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
511145011497	core domain interface [polypeptide binding]; other site
511145011498	delta subunit interface [polypeptide binding]; other site
511145011499	epsilon subunit interface [polypeptide binding]; other site
511145011500	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
511145011501	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
511145011502	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
511145011503	beta subunit interaction interface [polypeptide binding]; other site
511145011504	Walker A motif; other site
511145011505	ATP binding site [chemical binding]; other site
511145011506	Walker B motif; other site
511145011507	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
511145011508	F0F1 ATP synthase subunit delta; Validated; Region: PRK05758
511145011509	F0F1 ATP synthase subunit B; Validated; Region: PRK05759
511145011510	F0F1 ATP synthase subunit B; Provisional; Region: PRK14471; cl17192
511145011511	F0F1 ATP synthase subunit C; Validated; Region: PRK06876
511145011512	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
511145011513	F0F1 ATP synthase subunit I; Validated; Region: PRK08049
511145011514	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
511145011515	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145011516	S-adenosylmethionine binding site [chemical binding]; other site
511145011517	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
511145011518	tRNA:m(5)U-54 methyltransferase; Region: gid_trmFO; TIGR00137
511145011519	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
511145011520	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
511145011521	FMN-binding protein MioC; Provisional; Region: PRK09004
511145011522	DNA-binding transcriptional regulator AsnC; Provisional; Region: PRK11179
511145011523	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145011524	putative DNA binding site [nucleotide binding]; other site
511145011525	putative Zn2+ binding site [ion binding]; other site
511145011526	AsnC family; Region: AsnC_trans_reg; pfam01037
511145011527	Asparagine synthetase (aspartate-ammonia ligase) (AsnA) catalyses the conversion of L-aspartate to L-asparagine in the presence of ATP and ammonia.  AsnA is a homodimeric enzyme which is structurally similiar to the catalytic core domain of class II...; Region: AsnA; cd00645
511145011528	dimer interface [polypeptide binding]; other site
511145011529	active site
511145011530	Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only]; Region: COG2425
511145011531	VWA YIEM type: Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b...; Region: VWA_YIEM_type; cd01462
511145011532	metal ion-dependent adhesion site (MIDAS); other site
511145011533	regulatory ATPase RavA; Provisional; Region: PRK13531
511145011534	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145011535	Walker A motif; other site
511145011536	ATP binding site [chemical binding]; other site
511145011537	Walker B motif; other site
511145011538	arginine finger; other site
511145011539	Protein of unknown function (DUF3763); Region: DUF3763; pfam12592
511145011540	potassium transport protein Kup; Provisional; Region: trkD; PRK10745
511145011541	D-ribose pyranase; Provisional; Region: PRK11797
511145011542	D-ribose transporter ATP binding protein; Provisional; Region: PRK10762
511145011543	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145011544	Walker A/P-loop; other site
511145011545	ATP binding site [chemical binding]; other site
511145011546	Q-loop/lid; other site
511145011547	ABC transporter signature motif; other site
511145011548	Walker B; other site
511145011549	D-loop; other site
511145011550	H-loop/switch region; other site
511145011551	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145011552	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145011553	TM-ABC transporter signature motif; other site
511145011554	D-ribose transporter subunit RbsB; Provisional; Region: PRK10653
511145011555	Periplasmic sugar-binding domain of the thermophilic Thermoanaerobacter tengcongensis ribose binding protein (ttRBP) and its mesophilic homologs; Region: PBP1_ribose_binding; cd06323
511145011556	ligand binding site [chemical binding]; other site
511145011557	dimerization interface [polypeptide binding]; other site
511145011558	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
511145011559	substrate binding site [chemical binding]; other site
511145011560	dimer interface [polypeptide binding]; other site
511145011561	ATP binding site [chemical binding]; other site
511145011562	transcriptional repressor RbsR; Provisional; Region: PRK10423
511145011563	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145011564	DNA binding site [nucleotide binding]
511145011565	domain linker motif; other site
511145011566	Ligand-binding domain of purine repressor, PurR, which functions as the master regulatory protein of de novo purine nucleotide biosynthesis in Escherichia coli; Region: PBP1_PurR; cd06275
511145011567	dimerization interface [polypeptide binding]; other site
511145011568	ligand binding site [chemical binding]; other site
511145011569	putative transporter; Provisional; Region: PRK10504
511145011570	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011571	putative substrate translocation pore; other site
511145011572	Transcriptional regulators [Transcription]; Region: FadR; COG2186
511145011573	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145011574	DNA-binding site [nucleotide binding]; DNA binding site
511145011575	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145011576	transcriptional regulator HdfR; Provisional; Region: PRK03601
511145011577	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145011578	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
511145011579	dimerization interface [polypeptide binding]; other site
511145011580	hypothetical protein; Provisional; Region: PRK11027
511145011581	putative ATP-dependent protease; Provisional; Region: PRK09862
511145011582	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
511145011583	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145011584	Walker A motif; other site
511145011585	ATP binding site [chemical binding]; other site
511145011586	Walker B motif; other site
511145011587	arginine finger; other site
511145011588	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
511145011589	ilvG operon leader peptide; Provisional; Region: PRK10424
511145011590	acetolactate synthase 2 regulatory subunit; Provisional; Region: ilvM; PRK11152
511145011591	BCAT_beta_family: Branched-chain aminotransferase catalyses the transamination of the branched-chain amino acids  leusine, isoleucine and valine to their respective alpha-keto acids, alpha-ketoisocaproate, alpha-keto-beta-methylvalerate and...; Region: BCAT_beta_family; cd01557
511145011592	homodimer interface [polypeptide binding]; other site
511145011593	substrate-cofactor binding pocket; other site
511145011594	catalytic residue [active]
511145011595	dihydroxy-acid dehydratase; Provisional; Region: PRK12448
511145011596	threonine dehydratase; Reviewed; Region: PRK09224
511145011597	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
511145011598	tetramer interface [polypeptide binding]; other site
511145011599	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145011600	catalytic residue [active]
511145011601	First of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_1; cd04906
511145011602	putative Ile/Val binding site [chemical binding]; other site
511145011603	Second of two tandem C-terminal ACT domains of threonine dehydratase I (ThrD-I; L-threonine hydrolyase); Region: ACT_ThrD-I_2; cd04907
511145011604	putative Ile/Val binding site [chemical binding]; other site
511145011605	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145011606	DNA-binding transcriptional regulator IlvY; Provisional; Region: PRK11716
511145011607	The C-terminal substrate binding of LysR-type transcriptional regulator IlvY, which activates the expression of ilvC gene that encoding acetohydroxy acid isomeroreductase for the biosynthesis of branched amino acids; contains the type 2 periplasmic bindin; Region: PBP2_IlvY; cd08430
511145011608	putative dimerization interface [polypeptide binding]; other site
511145011609	ketol-acid reductoisomerase; Validated; Region: PRK05225
511145011610	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
511145011611	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
511145011612	peptidyl-prolyl cis-trans isomerase C; Provisional; Region: PRK15441
511145011613	Parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]; Region: SurA; COG0760
511145011614	ATP-dependent DNA helicase Rep; Provisional; Region: PRK10919
511145011615	Part of AAA domain; Region: AAA_19; pfam13245
511145011616	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
511145011617	guanosine pentaphosphate phosphohydrolase; Provisional; Region: PRK11031
511145011618	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
511145011619	ATP-dependent RNA helicase RhlB; Provisional; Region: PRK04837
511145011620	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
511145011621	ATP binding site [chemical binding]; other site
511145011622	Mg++ binding site [ion binding]; other site
511145011623	motif III; other site
511145011624	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145011625	nucleotide binding region [chemical binding]; other site
511145011626	ATP-binding site [chemical binding]; other site
511145011627	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
511145011628	catalytic residues [active]
511145011629	transcription termination factor Rho; Provisional; Region: rho; PRK09376
511145011630	Rho termination factor, N-terminal domain; Region: Rho_N; smart00959
511145011631	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
511145011632	RNA binding site [nucleotide binding]; other site
511145011633	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
511145011634	multimer interface [polypeptide binding]; other site
511145011635	Walker A motif; other site
511145011636	ATP binding site [chemical binding]; other site
511145011637	Walker B motif; other site
511145011638	undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; Region: ECA_wecA; TIGR02380
511145011639	This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond...; Region: GT_WecA_like; cd06853
511145011640	Mg++ binding site [ion binding]; other site
511145011641	putative catalytic motif [active]
511145011642	substrate binding site [chemical binding]; other site
511145011643	lipopolysaccharide biosynthesis protein WzzE; Provisional; Region: PRK11638
511145011644	Chain length determinant protein; Region: Wzz; pfam02706
511145011645	G-rich domain on putative tyrosine kinase; Region: GNVR; pfam13807
511145011646	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
511145011647	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
511145011648	active site
511145011649	homodimer interface [polypeptide binding]; other site
511145011650	UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional; Region: wecC; PRK11064
511145011651	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
511145011652	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
511145011653	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
511145011654	dTDP-glucose 4,6-dehydratase; Provisional; Region: PRK10217
511145011655	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
511145011656	NAD binding site [chemical binding]; other site
511145011657	substrate binding site [chemical binding]; other site
511145011658	homodimer interface [polypeptide binding]; other site
511145011659	active site
511145011660	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
511145011661	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
511145011662	substrate binding site; other site
511145011663	tetramer interface; other site
511145011664	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145011665	Coenzyme A binding pocket [chemical binding]; other site
511145011666	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
511145011667	inhibitor-cofactor binding pocket; inhibition site
511145011668	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145011669	catalytic residue [active]
511145011670	Membrane protein involved in the export of O-antigen and teichoic acid [General function prediction only]; Region: RfbX; COG2244
511145011671	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_10; cd13125
511145011672	4-alpha-L-fucosyltransferase glycosyl transferase group 56; Region: Glyco_transf_56; pfam07429
511145011673	putative common antigen polymerase; Provisional; Region: PRK02975
511145011674	The glycosyltransferase WecG/TagA superfamily contains Escherichia coli WecG, Bacillus subtilis TagA and related proteins. E. coli WecG is believed to be a UDP-N-acetyl-D-mannosaminuronic acid transferase, and is involved in enterobacterial common...; Region: Glyco_transf_WecG_TagA; cd06533
511145011675	putative transport protein YifK; Provisional; Region: PRK10746
511145011676	anaerobic sulfatase-maturating enzyme; Region: sulfatase_rSAM; TIGR03942
511145011677	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145011678	FeS/SAM binding site; other site
511145011679	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
511145011680	Arylsulfatase A and related enzymes [Inorganic ion transport and metabolism]; Region: AslA; COG3119
511145011681	Sulfatase; Region: Sulfatase; pfam00884
511145011682	putative protoheme IX biogenesis protein; Provisional; Region: PRK10747
511145011683	HemY protein N-terminus; Region: HemY_N; pfam07219
511145011684	putative uroporphyrinogen III C-methyltransferase; Provisional; Region: PRK10920
511145011685	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
511145011686	active site
511145011687	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
511145011688	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
511145011689	domain interfaces; other site
511145011690	active site
511145011691	Adenylate cyclase [Nucleotide transport and metabolism]; Region: CyaA; COG3072
511145011692	Adenylate cyclase NT domain; Region: Adenyl_cycl_N; pfam12633
511145011693	Adenylate cyclase, class-I; Region: Adenylate_cycl; pfam01295
511145011694	Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreich's ataxia (FRDA), an human autosomal recessive neurodegenerative disease; Frataxin is found in eukaryotes and in purple bacteria; lack of frataxin causes iron to accumulate...; Region: Frataxin; cd00503
511145011695	putative iron binding site [ion binding]; other site
511145011696	Predicted small periplasmic lipoprotein [Cell motility and secretion]; Region: COG5567
511145011697	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
511145011698	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
511145011699	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
511145011700	hypothetical protein; Provisional; Region: PRK10963
511145011701	Site-specific recombinase XerC [DNA replication, recombination, and repair]; Region: XerC; COG4973
511145011702	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
511145011703	active site
511145011704	Int/Topo IB signature motif; other site
511145011705	flavin mononucleotide phosphatase; Provisional; Region: PRK10748
511145011706	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
511145011707	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145011708	motif II; other site
511145011709	DNA-dependent helicase II; Provisional; Region: uvrD; PRK11773
511145011710	Part of AAA domain; Region: AAA_19; pfam13245
511145011711	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
511145011712	Predicted periplasmic protein [Function unknown]; Region: COG3698
511145011713	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
511145011714	Escherichia coli Mg2+ transporter CorA_like subgroup; Region: EcCorA-like_1; cd12835
511145011715	Cl binding site [ion binding]; other site
511145011716	oligomer interface [polypeptide binding]; other site
511145011717	Protein of unknown function (DUF2628); Region: DUF2628; pfam10947
511145011718	hypothetical protein; Provisional; Region: PRK11371
511145011719	putative chloramphenical resistance permease RarD; Provisional; Region: PRK15430
511145011720	Multidrug resistance efflux transporter; Region: EmrE; cl19304
511145011721	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
511145011722	Thioesterase-like superfamily; Region: 4HBT_3; pfam13622
511145011723	CoenzymeA binding site [chemical binding]; other site
511145011724	subunit interaction site [polypeptide binding]; other site
511145011725	PHB binding site; other site
511145011726	The outer membrane phospholipase A (OMPLA) is an integral membrane enzyme that catalyses the hydrolysis of acylester bonds in phospholipids using calcium as a cofactor. The enzyme has a fold of transmembrane beta-barrels and is widespread among...; Region: OMPLA; cd00541
511145011727	dimerization interface [polypeptide binding]; other site
511145011728	substrate binding site [chemical binding]; other site
511145011729	active site
511145011730	calcium binding site [ion binding]; other site
511145011731	ATP-dependent DNA helicase RecQ; Provisional; Region: PRK11057
511145011732	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145011733	ATP binding site [chemical binding]; other site
511145011734	putative Mg++ binding site [ion binding]; other site
511145011735	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145011736	nucleotide binding region [chemical binding]; other site
511145011737	ATP-binding site [chemical binding]; other site
511145011738	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
511145011739	Helicase and RNase D C-terminal; Region: HRDC; smart00341
511145011740	threonine efflux system; Provisional; Region: PRK10229
511145011741	homoserine/homoserine lactone efflux protein; Provisional; Region: rhtB; PRK10520
511145011742	lysophospholipase L2; Provisional; Region: PRK10749
511145011743	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
511145011744	putative hydrolase; Provisional; Region: PRK10976
511145011745	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145011746	active site
511145011747	motif I; other site
511145011748	motif II; other site
511145011749	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
511145011750	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
511145011751	EamA-like transporter family; Region: EamA; pfam00892
511145011752	DNA-binding transcriptional regulator MetR; Provisional; Region: PRK15421
511145011753	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145011754	The C-terminal substrate binding domain of LysR-type transcriptional regulator metR, which regulates the expression of methionine biosynthetic genes, contains type 2 periplasmic binding fold; Region: PBP2_MetR; cd08441
511145011755	putative dimerization interface [polypeptide binding]; other site
511145011756	5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; Provisional; Region: PRK05222
511145011757	CIMS - Cobalamine-independent methonine synthase, or MetE, N-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_N_terminal_like; cd03312
511145011758	THF binding site; other site
511145011759	CIMS - Cobalamine-independent methonine synthase, or MetE, C-terminal domain_like. Many members have been characterized as 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferases, EC:2.1.1.14, mostly from bacteria and plants. This enzyme...; Region: CIMS_C_terminal_like; cd03311
511145011760	substrate binding site [chemical binding]; other site
511145011761	THF binding site; other site
511145011762	zinc-binding site [ion binding]; other site
511145011763	Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG0412
511145011764	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
511145011765	uridine phosphorylase; Provisional; Region: PRK11178
511145011766	DNA recombination protein RmuC; Provisional; Region: PRK10361
511145011767	RmuC family; Region: RmuC; pfam02646
511145011768	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
511145011769	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145011770	S-adenosylmethionine binding site [chemical binding]; other site
511145011771	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3165
511145011772	putative ubiquinone biosynthesis protein UbiB; Reviewed; Region: ubiB; PRK04750
511145011773	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
511145011774	twin arginine translocase protein A; Provisional; Region: tatA; PRK03554
511145011775	sec-independent translocase; Provisional; Region: PRK01770
511145011776	sec-independent translocase; Provisional; Region: tatB; PRK00404
511145011777	twin-arginine protein translocation system subunit TatC; Provisional; Region: PRK10921
511145011778	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
511145011779	active site
511145011780	transcriptional activator RfaH; Provisional; Region: rfaH; PRK09014
511145011781	N-Utilization Substance G (NusG) N-terminal domain in the NusG Specialized Paralog (SP), RfaH; Region: NGN_SP_RfaH; cd09892
511145011782	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
511145011783	3-octaprenyl-4-hydroxybenzoate decarboxylase; Provisional; Region: PRK10922
511145011784	FMN reductase; Validated; Region: fre; PRK08051
511145011785	NAD(P)H dependent flavin oxidoreductases use flavin as a substrate in mediating electron transfer from iron complexes or iron proteins. Structurally similar to ferredoxin reductases, but with only 15% sequence identity, flavin reductases reduce FAD, FMN; Region: flavin_oxioreductase; cd06189
511145011786	FAD binding pocket [chemical binding]; other site
511145011787	FAD binding motif [chemical binding]; other site
511145011788	phosphate binding motif [ion binding]; other site
511145011789	beta-alpha-beta structure motif; other site
511145011790	NAD binding pocket [chemical binding]; other site
511145011791	3-ketoacyl-CoA thiolase; Reviewed; Region: fadA; PRK08947
511145011792	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
511145011793	dimer interface [polypeptide binding]; other site
511145011794	active site
511145011795	multifunctional fatty acid oxidation complex subunit alpha; Reviewed; Region: fadB; PRK11730
511145011796	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
511145011797	substrate binding site [chemical binding]; other site
511145011798	oxyanion hole (OAH) forming residues; other site
511145011799	trimer interface [polypeptide binding]; other site
511145011800	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
511145011801	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145011802	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
511145011803	proline dipeptidase; Provisional; Region: PRK13607
511145011804	Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on...; Region: Prolidase; cd01087
511145011805	active site
511145011806	hypothetical protein; Provisional; Region: PRK11568
511145011807	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
511145011808	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
511145011809	potassium transporter; Provisional; Region: PRK10750
511145011810	Trk-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: TrkG; COG0168
511145011811	protoporphyrinogen oxidase; Provisional; Region: hemG; PRK11104
511145011812	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
511145011813	Walker A motif; other site
511145011814	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
511145011815	GTP binding site; other site
511145011816	Protein of unknown function (DUF1040); Region: DUF1040; pfam06288
511145011817	serine/threonine protein kinase; Provisional; Region: PRK11768
511145011818	Phosphotransferase enzyme family; Region: APH; pfam01636
511145011819	DsbA family, DsbA subfamily; DsbA is a monomeric thiol disulfide oxidoreductase protein containing a redox active CXXC motif imbedded in a TRX fold. It is involved in the oxidative protein folding pathway in prokaryotes, and is the strongest thiol...; Region: DsbA_DsbA; cd03019
511145011820	catalytic residues [active]
511145011821	hinge region; other site
511145011822	alpha helical domain; other site
511145011823	hypothetical protein; Provisional; Region: PRK11367
511145011824	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LCLAT1-like; Region: LPLAT_LCLAT1-like; cd07990
511145011825	putative acyl-acceptor binding pocket; other site
511145011826	DNA polymerase I; Provisional; Region: PRK05755
511145011827	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
511145011828	active site
511145011829	metal binding site 1 [ion binding]; metal-binding site
511145011830	putative 5' ssDNA interaction site; other site
511145011831	metal binding site 3; metal-binding site
511145011832	metal binding site 2 [ion binding]; metal-binding site
511145011833	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
511145011834	putative DNA binding site [nucleotide binding]; other site
511145011835	putative metal binding site [ion binding]; other site
511145011836	DEDDy 3'-5' exonuclease domain of Escherichia coli DNA polymerase I and similar bacterial family-A DNA polymerases; Region: DNA_polA_I_Ecoli_like_exo; cd06139
511145011837	active site
511145011838	catalytic site [active]
511145011839	substrate binding site [chemical binding]; other site
511145011840	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
511145011841	active site
511145011842	DNA binding site [nucleotide binding]
511145011843	catalytic site [active]
511145011844	Predicted GTPase [General function prediction only]; Region: COG0218
511145011845	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
511145011846	G1 box; other site
511145011847	GTP/Mg2+ binding site [chemical binding]; other site
511145011848	Switch I region; other site
511145011849	G2 box; other site
511145011850	G3 box; other site
511145011851	Switch II region; other site
511145011852	G4 box; other site
511145011853	G5 box; other site
511145011854	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3078
511145011855	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
511145011856	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145011857	FeS/SAM binding site; other site
511145011858	HemN C-terminal domain; Region: HemN_C; pfam06969
511145011859	nitrogen regulation protein NR(I); Provisional; Region: glnG; PRK10923
511145011860	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145011861	active site
511145011862	phosphorylation site [posttranslational modification]
511145011863	intermolecular recognition site; other site
511145011864	dimerization interface [polypeptide binding]; other site
511145011865	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145011866	Walker A motif; other site
511145011867	ATP binding site [chemical binding]; other site
511145011868	Walker B motif; other site
511145011869	arginine finger; other site
511145011870	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145011871	nitrogen regulation protein NR(II); Provisional; Region: glnL; PRK11073
511145011872	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145011873	putative active site [active]
511145011874	heme pocket [chemical binding]; other site
511145011875	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145011876	dimer interface [polypeptide binding]; other site
511145011877	phosphorylation site [posttranslational modification]
511145011878	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145011879	ATP binding site [chemical binding]; other site
511145011880	Mg2+ binding site [ion binding]; other site
511145011881	G-X-G motif; other site
511145011882	glutamine synthetase; Provisional; Region: glnA; PRK09469
511145011883	Glutamine synthetase, beta-Grasp domain; Region: Gln-synt_N; pfam03951
511145011884	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
511145011885	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
511145011886	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
511145011887	G1 box; other site
511145011888	putative GEF interaction site [polypeptide binding]; other site
511145011889	GTP/Mg2+ binding site [chemical binding]; other site
511145011890	Switch I region; other site
511145011891	G2 box; other site
511145011892	G3 box; other site
511145011893	Switch II region; other site
511145011894	G4 box; other site
511145011895	G5 box; other site
511145011896	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
511145011897	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
511145011898	transcriptional regulator protein; Region: phnR; TIGR03337
511145011899	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145011900	DNA-binding site [nucleotide binding]; DNA binding site
511145011901	UTRA domain; Region: UTRA; pfam07702
511145011902	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
511145011903	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011904	putative substrate translocation pore; other site
511145011905	phosphoglycerate transporter family protein; Region: 2A0104; TIGR00881
511145011906	outer membrane porin L; Provisional; Region: ompL; PRK09980
511145011907	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
511145011908	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011909	putative substrate translocation pore; other site
511145011910	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
511145011911	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145011912	putative substrate translocation pore; other site
511145011913	alpha-glucosidase; Provisional; Region: PRK10426
511145011914	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
511145011915	YihQ is a bacterial alpha-glucosidase with a conserved glycosyl hydrolase family 31 (GH31) domain that catalyzes the release of an alpha-glucosyl residue from the non-reducing end of alpha-glucoside substrates such as alpha-glucosyl fluoride. Orthologs...; Region: GH31_glucosidase_YihQ; cd06594
511145011916	putative active site [active]
511145011917	putative catalytic site [active]
511145011918	Aldose 1-epimerase, similar to Escherichia coli YihR; Region: Aldose_epim_Ec_YihR; cd09022
511145011919	active site
511145011920	catalytic residues [active]
511145011921	AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is...; Region: AGE; cd00249
511145011922	dimerization interface [polypeptide binding]; other site
511145011923	putative active cleft [active]
511145011924	Tagatose-1,6-bisphosphate aldolase [Carbohydrate transport and metabolism]; Region: LacD; COG3684
511145011925	catalytic residue [active]
511145011926	NADH-dependent gamma-hydroxybutyrate dehydrogenase; Provisional; Region: PRK15461
511145011927	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
511145011928	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
511145011929	Ribokinase-like subgroup B.  Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily.  Its oligomerization state is unknown at this time; Region: ribokinase_group_B; cd01945
511145011930	substrate binding site [chemical binding]; other site
511145011931	ATP binding site [chemical binding]; other site
511145011932	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
511145011933	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
511145011934	putative DNA binding site [nucleotide binding]; other site
511145011935	putative Zn2+ binding site [ion binding]; other site
511145011936	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145011937	haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Region: HAD-SF-IA-v3; TIGR01509
511145011938	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
511145011939	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145011940	motif II; other site
511145011941	hypothetical protein; Reviewed; Region: PRK01637
511145011942	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
511145011943	putative active site [active]
511145011944	dimerization interface [polypeptide binding]; other site
511145011945	putative tRNAtyr binding site [nucleotide binding]; other site
511145011946	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145011947	Coenzyme A binding pocket [chemical binding]; other site
511145011948	Putative thioesterase (yiiD_Cterm); Region: YiiD_Cterm; pfam09500
511145011949	Ribbon-helix-helix protein, copG family; Region: RHH_1; pfam01402
511145011950	formate dehydrogenase accessory protein FdhE; Provisional; Region: PRK03564
511145011951	formate dehydrogenase-O subunit gamma; Provisional; Region: PRK10639
511145011952	formate dehydrogenase, beta subunit, Fe-S containing; Region: FDH-beta; TIGR01582
511145011953	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145011954	Formate dehydrogenase N, transmembrane; Region: Form-deh_trans; pfam09163
511145011955	formate dehydrogenase, alpha subunit, proteobacterial-type; Region: formate-DH-alph; TIGR01553
511145011956	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_Formate-Dh-Na-like; cd02752
511145011957	[4Fe-4S] binding site [ion binding]; other site
511145011958	molybdopterin cofactor binding site; other site
511145011959	Formate dehydrogenase N, alpha subunit (Formate-Dh-Na) is a major component of nitrate respiration in bacteria such as in the E. coli formate dehydrogenase N (Fdh-N). Fdh-N is a membrane protein that is a complex of three different subunits and is the...; Region: MopB_CT_Formate-Dh-Na-like; cd02792
511145011960	molybdopterin cofactor binding site; other site
511145011961	formate dehydrogenase accessory protein; Reviewed; Region: PRK00724
511145011962	Protein of unknown function (DUF3829); Region: DUF3829; pfam12889
511145011963	putative frv operon regulatory protein; Provisional; Region: PRK09863
511145011964	HTH domain; Region: HTH_11; pfam08279
511145011965	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145011966	active site
511145011967	phosphorylation site [posttranslational modification]
511145011968	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
511145011969	oligomer interface [polypeptide binding]; other site
511145011970	active site
511145011971	metal binding site [ion binding]; metal-binding site
511145011972	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
511145011973	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145011974	active site
511145011975	P-loop; other site
511145011976	phosphorylation site [posttranslational modification]
511145011977	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
511145011978	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145011979	active site
511145011980	phosphorylation site [posttranslational modification]
511145011981	L-rhamnose 1-epimerase; Region: YiiL_rotase; TIGR02625
511145011982	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
511145011983	intersubunit interface [polypeptide binding]; other site
511145011984	active site
511145011985	Zn2+ binding site [ion binding]; other site
511145011986	L-rhamnose isomerase; Provisional; Region: PRK01076
511145011987	L-rhamnulose kinases; a subfamily of the FGGY family of carbohydrate kinases; Region: FGGY_RhuK; cd07771
511145011988	N- and C-terminal domain interface [polypeptide binding]; other site
511145011989	active site
511145011990	putative catalytic site [active]
511145011991	metal binding site [ion binding]; metal-binding site
511145011992	ATP binding site [chemical binding]; other site
511145011993	rhamnulokinase; Provisional; Region: rhaB; PRK10640
511145011994	carbohydrate binding site [chemical binding]; other site
511145011995	transcriptional activator RhaS; Provisional; Region: PRK13503
511145011996	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
511145011997	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145011998	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145011999	transcriptional activator RhaR; Provisional; Region: PRK13500
511145012000	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
511145012001	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012002	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012003	Sugar transport protein; Region: Sugar_transport; cl19288
511145012004	superoxide dismutase; Provisional; Region: PRK10925
511145012005	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
511145012006	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
511145012007	2-keto-3-deoxygluconate permease; Region: KdgT; cl14653
511145012008	6-N-hydroxylaminopurine resistance protein; Provisional; Region: PRK11536
511145012009	MOSC domain; Region: MOSC; pfam03473
511145012010	3-alpha domain; Region: 3-alpha; pfam03475
511145012011	two-component sensor protein; Provisional; Region: cpxA; PRK09470
511145012012	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145012013	dimerization interface [polypeptide binding]; other site
511145012014	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145012015	dimer interface [polypeptide binding]; other site
511145012016	phosphorylation site [posttranslational modification]
511145012017	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145012018	ATP binding site [chemical binding]; other site
511145012019	Mg2+ binding site [ion binding]; other site
511145012020	G-X-G motif; other site
511145012021	DNA-binding transcriptional regulator CpxR; Provisional; Region: PRK10955
511145012022	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145012023	active site
511145012024	intermolecular recognition site; other site
511145012025	dimerization interface [polypeptide binding]; other site
511145012026	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145012027	DNA binding site [nucleotide binding]
511145012028	CpxP component of the bacterial Cpx-two-component system and related proteins; Region: CpxP_like; cd09916
511145012029	dimer interface [polypeptide binding]; other site
511145012030	ferrous iron efflux protein F; Reviewed; Region: fieF; PRK09509
511145012031	Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent...; Region: Bacterial_PFK; cd00763
511145012032	active site
511145012033	ADP/pyrophosphate binding site [chemical binding]; other site
511145012034	dimerization interface [polypeptide binding]; other site
511145012035	allosteric effector site; other site
511145012036	fructose-1,6-bisphosphate binding site; other site
511145012037	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
511145012038	substrate binding pocket [chemical binding]; other site
511145012039	membrane-bound complex binding site; other site
511145012040	hinge residues; other site
511145012041	CDP-diacylglycerol pyrophosphatase, bacterial type; Region: cdh; TIGR00672
511145012042	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
511145012043	substrate binding site [chemical binding]; other site
511145012044	dimer interface [polypeptide binding]; other site
511145012045	catalytic triad [active]
511145012046	Protein of unknown function (DUF1454); Region: DUF1454; pfam07305
511145012047	Predicted membrane protein [Function unknown]; Region: COG3152
511145012048	hypothetical protein; Provisional; Region: PRK09981
511145012049	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
511145012050	Ligand Binding Site [chemical binding]; other site
511145012051	ferredoxin-NADP reductase; Provisional; Region: PRK10926
511145012052	Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently...; Region: FNR1; cd06195
511145012053	FAD binding pocket [chemical binding]; other site
511145012054	FAD binding motif [chemical binding]; other site
511145012055	phosphate binding motif [ion binding]; other site
511145012056	beta-alpha-beta structure motif; other site
511145012057	NAD binding pocket [chemical binding]; other site
511145012058	Bacterial fructose-1,6-bisphosphatase, glpX-encoded. A dimeric enzyme dependent on Mg(2+). glpX-encoded FPBase (FBPase class II) differs from other members of the inositol-phosphatase superfamily by permutation of secondary structure elements. The core...; Region: FBPase_glpX; cd01516
511145012059	putative active site [active]
511145012060	glycerol kinase; Provisional; Region: glpK; PRK00047
511145012061	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
511145012062	N- and C-terminal domain interface [polypeptide binding]; other site
511145012063	active site
511145012064	MgATP binding site [chemical binding]; other site
511145012065	catalytic site [active]
511145012066	metal binding site [ion binding]; metal-binding site
511145012067	glycerol binding site [chemical binding]; other site
511145012068	homotetramer interface [polypeptide binding]; other site
511145012069	homodimer interface [polypeptide binding]; other site
511145012070	FBP binding site [chemical binding]; other site
511145012071	protein IIAGlc interface [polypeptide binding]; other site
511145012072	Major intrinsic protein (MIP) superfamily. Members of the MIP superfamily function as membrane channels that selectively transport water, small neutral molecules, and ions out of and between cells. The channel proteins share a common fold: the N-terminal...; Region: MIP; cd00333
511145012073	amphipathic channel; other site
511145012074	Asn-Pro-Ala signature motifs; other site
511145012075	septal ring assembly protein ZapB; Provisional; Region: PRK15422
511145012076	ribonuclease activity regulator protein RraA; Provisional; Region: PRK09372
511145012077	1,4-Dihydroxy-2-naphthoate octaprenyltransferase; Region: PT_UbiA_UBIAD1; cd13962
511145012078	putative active site [active]
511145012079	ATP-dependent protease ATP-binding subunit HslU; Provisional; Region: hslU; PRK05201
511145012080	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145012081	Walker A motif; other site
511145012082	ATP binding site [chemical binding]; other site
511145012083	AAA domain (Cdc48 subfamily); Region: AAA_2; pfam07724
511145012084	Walker B motif; other site
511145012085	arginine finger; other site
511145012086	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
511145012087	Protease HslV and the ATPase/chaperone HslU are part of an ATP-dependent proteolytic system that is the prokaryotic homolog of the proteasome. HslV is a dimer of hexamers (a dodecamer) that forms a central proteolytic chamber with active sites on the...; Region: protease_HslV; cd01913
511145012088	active site
511145012089	HslU subunit interaction site [polypeptide binding]; other site
511145012090	essential cell division protein FtsN; Provisional; Region: PRK10927
511145012091	Sporulation related domain; Region: SPOR; pfam05036
511145012092	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145012093	DNA binding site [nucleotide binding]
511145012094	DNA-binding transcriptional regulator CytR; Provisional; Region: PRK11041
511145012095	domain linker motif; other site
511145012096	Ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria; Region: PBP1_LacI_like_6; cd06284
511145012097	dimerization interface [polypeptide binding]; other site
511145012098	ligand binding site [chemical binding]; other site
511145012099	primosome assembly protein PriA; Validated; Region: PRK05580
511145012100	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145012101	ATP binding site [chemical binding]; other site
511145012102	putative Mg++ binding site [ion binding]; other site
511145012103	helicase superfamily c-terminal domain; Region: HELICc; smart00490
511145012104	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
511145012105	hypothetical protein; Provisional; Region: PRK10030
511145012106	Met Repressor, MetJ.  MetJ is a bacterial regulatory protein that uses S-adenosylmethionine (SAM) as a corepressor to regulate the production of Methionine. MetJ binds arrays of two to five adjacent copies of an eight base-pair 'metbox'...; Region: Met_repressor_MetJ; cd00490
511145012107	dimerization interface [polypeptide binding]; other site
511145012108	DNA binding site [nucleotide binding]
511145012109	corepressor binding sites; other site
511145012110	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
511145012111	homodimer interface [polypeptide binding]; other site
511145012112	substrate-cofactor binding pocket; other site
511145012113	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145012114	catalytic residue [active]
511145012115	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
511145012116	AAK_AK-HSDH: Amino Acid Kinase Superfamily (AAK), AK-HSDH; this CD includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK - homoserine dehydrogenase (HSDH). These aspartokinases are found in bacteria (E. coli...; Region: AAK_AK-HSDH; cd04257
511145012117	putative catalytic residues [active]
511145012118	putative nucleotide binding site [chemical binding]; other site
511145012119	putative aspartate binding site [chemical binding]; other site
511145012120	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like_2; cd04892
511145012121	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
511145012122	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
511145012123	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
511145012124	FAD binding site [chemical binding]; other site
511145012125	catalase/hydroperoxidase HPI(I); Provisional; Region: PRK15061
511145012126	Heme-dependent peroxidases similar to plant peroxidases; Region: plant_peroxidase_like; cl00196
511145012127	heme binding site [chemical binding]; other site
511145012128	C-terminal non-catalytic domain of catalase-peroxidases; Region: catalase_peroxidase_2; cd08200
511145012129	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
511145012130	EamA-like transporter family; Region: EamA; pfam00892
511145012131	EamA-like transporter family; Region: EamA; pfam00892
511145012132	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3738
511145012133	Glycerol dehydrogenases (GlyDH) catalyzes oxidation of glycerol to dihydroxyacetone in glycerol dissmilation; Region: GlyDH; cd08170
511145012134	dimer interface [polypeptide binding]; other site
511145012135	active site
511145012136	metal binding site [ion binding]; metal-binding site
511145012137	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
511145012138	active site
511145012139	intersubunit interactions; other site
511145012140	catalytic residue [active]
511145012141	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
511145012142	dimerization domain swap beta strand [polypeptide binding]; other site
511145012143	regulatory protein interface [polypeptide binding]; other site
511145012144	active site
511145012145	regulatory phosphorylation site [posttranslational modification]; other site
511145012146	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
511145012147	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
511145012148	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
511145012149	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
511145012150	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145012151	active site
511145012152	phosphorylation site [posttranslational modification]
511145012153	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
511145012154	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145012155	active site
511145012156	P-loop; other site
511145012157	phosphorylation site [posttranslational modification]
511145012158	putative formate acetyltransferase 2; Provisional; Region: pflD; PRK09983
511145012159	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
511145012160	dimer interface [polypeptide binding]; other site
511145012161	active site
511145012162	glycine loop; other site
511145012163	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
511145012164	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145012165	FeS/SAM binding site; other site
511145012166	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
511145012167	active site
511145012168	P-loop; other site
511145012169	phosphorylation site [posttranslational modification]
511145012170	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012171	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145012172	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012173	hypothetical protein; Provisional; Region: PRK10649
511145012174	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
511145012175	Sulfatase; Region: Sulfatase; pfam00884
511145012176	phosphoenolpyruvate carboxylase; Reviewed; Region: PRK00009
511145012177	acetylornithine deacetylase (ArgE); Region: AcOrn-deacetyl; TIGR01892
511145012178	M20 Peptidase acetylornithine deacetylase; Region: M20_ArgE; cd03894
511145012179	metal binding site [ion binding]; metal-binding site
511145012180	putative dimer interface [polypeptide binding]; other site
511145012181	N-acetyl-gamma-glutamyl-phosphate reductase, common form; Region: argC; TIGR01850
511145012182	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
511145012183	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
511145012184	AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of...; Region: AAK_NAGK-NC; cd04249
511145012185	nucleotide binding site [chemical binding]; other site
511145012186	N-acetyl-L-glutamate binding site [chemical binding]; other site
511145012187	argininosuccinate lyase; Provisional; Region: PRK04833
511145012188	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
511145012189	active sites [active]
511145012190	tetramer interface [polypeptide binding]; other site
511145012191	DNA-binding transcriptional regulator OxyR; Provisional; Region: PRK11151
511145012192	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145012193	The C-terminal substrate-binding domain of the LysR-type transcriptional regulator OxyR, a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_OxyR; cd08411
511145012194	dimerization interface [polypeptide binding]; other site
511145012195	soluble pyridine nucleotide transhydrogenase; Provisional; Region: PRK05249
511145012196	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
511145012197	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
511145012198	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
511145012199	DNA-binding transcriptional repressor FabR; Provisional; Region: PRK11202
511145012200	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145012201	hypothetical protein; Provisional; Region: PRK11056
511145012202	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
511145012203	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145012204	S-adenosylmethionine binding site [chemical binding]; other site
511145012205	vitamin B12/cobalamin outer membrane transporter; Provisional; Region: btuB; PRK10641
511145012206	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145012207	N-terminal plug; other site
511145012208	ligand-binding site [chemical binding]; other site
511145012209	glutamate racemase; Provisional; Region: PRK00865
511145012210	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK00046
511145012211	FAD binding domain; Region: FAD_binding_4; pfam01565
511145012212	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
511145012213	Biotin operon repressor [Transcription]; Region: BirA; COG1654
511145012214	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
511145012215	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
511145012216	Biotin protein ligase C terminal domain; Region: BPL_C; pfam02237
511145012217	Pantothenate kinase (PanK) catalyzes the phosphorylation of pantothenic acid to form 4'-phosphopantothenic, which is the first of five steps in coenzyme A (CoA) biosynthetic pathway. The reaction carried out by this enzyme is a key regulatory point...; Region: PanK; cd02025
511145012218	ATP-binding site [chemical binding]; other site
511145012219	CoA-binding site [chemical binding]; other site
511145012220	Mg2+-binding site [ion binding]; other site
511145012221	elongation factor Tu; Reviewed; Region: PRK00049
511145012222	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
511145012223	G1 box; other site
511145012224	GEF interaction site [polypeptide binding]; other site
511145012225	GTP/Mg2+ binding site [chemical binding]; other site
511145012226	Switch I region; other site
511145012227	G2 box; other site
511145012228	G3 box; other site
511145012229	Switch II region; other site
511145012230	G4 box; other site
511145012231	G5 box; other site
511145012232	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
511145012233	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
511145012234	Antibiotic Binding Site [chemical binding]; other site
511145012235	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK05740
511145012236	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
511145012237	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
511145012238	putative homodimer interface [polypeptide binding]; other site
511145012239	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
511145012240	heterodimer interface [polypeptide binding]; other site
511145012241	homodimer interface [polypeptide binding]; other site
511145012242	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
511145012243	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
511145012244	23S rRNA interface [nucleotide binding]; other site
511145012245	L7/L12 interface [polypeptide binding]; other site
511145012246	putative thiostrepton binding site; other site
511145012247	L25 interface [polypeptide binding]; other site
511145012248	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
511145012249	mRNA/rRNA interface [nucleotide binding]; other site
511145012250	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
511145012251	23S rRNA interface [nucleotide binding]; other site
511145012252	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
511145012253	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
511145012254	core dimer interface [polypeptide binding]; other site
511145012255	peripheral dimer interface [polypeptide binding]; other site
511145012256	L10 interface [polypeptide binding]; other site
511145012257	L11 interface [polypeptide binding]; other site
511145012258	putative EF-Tu interaction site [polypeptide binding]; other site
511145012259	putative EF-G interaction site [polypeptide binding]; other site
511145012260	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
511145012261	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
511145012262	RPB12 interaction site [polypeptide binding]; other site
511145012263	RPB1 interaction site [polypeptide binding]; other site
511145012264	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
511145012265	RPB10 interaction site [polypeptide binding]; other site
511145012266	RPB11 interaction site [polypeptide binding]; other site
511145012267	RPB3 interaction site [polypeptide binding]; other site
511145012268	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
511145012269	beta and beta' interface [polypeptide binding]; other site
511145012270	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
511145012271	beta' and sigma factor interface [polypeptide binding]; other site
511145012272	Zn-binding [ion binding]; other site
511145012273	active site region [active]
511145012274	catalytic site [active]
511145012275	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
511145012276	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
511145012277	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
511145012278	G-loop; other site
511145012279	DNA binding site [nucleotide binding]
511145012280	stationary phase growth adaptation protein; Provisional; Region: PRK09717
511145012281	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
511145012282	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145012283	FeS/SAM binding site; other site
511145012284	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
511145012285	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
511145012286	ThiS interaction site; other site
511145012287	putative active site [active]
511145012288	tetramer interface [polypeptide binding]; other site
511145012289	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
511145012290	thiS-thiF/thiG interaction site; other site
511145012291	ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD...; Region: ThiF_MoeB_HesA_family; cd00757
511145012292	thiazole biosynthesis adenylyltransferase ThiF, E. coli subfamily; Region: adenyl_thiF; TIGR02356
511145012293	ATP binding site [chemical binding]; other site
511145012294	substrate interface [chemical binding]; other site
511145012295	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
511145012296	thiamine phosphate binding site [chemical binding]; other site
511145012297	active site
511145012298	pyrophosphate binding site [ion binding]; other site
511145012299	thiamine biosynthesis protein ThiC; Provisional; Region: PRK09284
511145012300	ThiC-associated domain; Region: ThiC-associated; pfam13667
511145012301	ThiC family; Region: ThiC; pfam01964
511145012302	Regulator of sigma D [Transcription]; Region: Rsd; COG3160
511145012303	NADH pyrophosphatase; Reviewed; Region: nudC; PRK00241
511145012304	NADH pyrophosphatase-like rudimentary NUDIX domain; Region: NUDIX-like; pfam09296
511145012305	NADH pyrophosphatase zinc ribbon domain; Region: zf-NADH-PPase; pfam09297
511145012306	NADH pyrophosphatase, a member of the Nudix hydrolase superfamily, catalyzes the cleavage of NADH into reduced nicotinamide mononucleotide (NMNH) and AMP. Like other members of the Nudix family, it requires a divalent cation, such as Mg2+ or Mn2+, for...; Region: NADH_pyrophosphatase; cd03429
511145012307	putative NADH binding site [chemical binding]; other site
511145012308	putative active site [active]
511145012309	nudix motif; other site
511145012310	putative metal binding site [ion binding]; other site
511145012311	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
511145012312	substrate binding site [chemical binding]; other site
511145012313	active site
511145012314	Endonuclease_V, a DNA repair enzyme that initiates repair of nitrosative deaminated purine bases; Region: Endonuclease_V; cd06559
511145012315	Active_site [active]
511145012316	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3068
511145012317	histone-like DNA-binding protein HU; Region: HU; cd13831
511145012318	dimer interface [polypeptide binding]; other site
511145012319	DNA binding site [nucleotide binding]
511145012320	Protein of unknown function (DUF1481); Region: DUF1481; pfam07356
511145012321	zinc resistance protein; Provisional; Region: zraP; PRK11546
511145012322	dimer interface [polypeptide binding]; other site
511145012323	sensor protein ZraS; Provisional; Region: PRK10364
511145012324	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145012325	dimer interface [polypeptide binding]; other site
511145012326	phosphorylation site [posttranslational modification]
511145012327	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145012328	ATP binding site [chemical binding]; other site
511145012329	Mg2+ binding site [ion binding]; other site
511145012330	G-X-G motif; other site
511145012331	transcriptional regulatory protein ZraR; Provisional; Region: PRK10365
511145012332	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145012333	active site
511145012334	phosphorylation site [posttranslational modification]
511145012335	intermolecular recognition site; other site
511145012336	dimerization interface [polypeptide binding]; other site
511145012337	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145012338	Walker A motif; other site
511145012339	ATP binding site [chemical binding]; other site
511145012340	Walker B motif; other site
511145012341	arginine finger; other site
511145012342	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
511145012343	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
511145012344	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
511145012345	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
511145012346	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
511145012347	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
511145012348	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
511145012349	purine monophosphate binding site [chemical binding]; other site
511145012350	dimer interface [polypeptide binding]; other site
511145012351	putative catalytic residues [active]
511145012352	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
511145012353	hypothetical protein; Provisional; Region: PRK10039
511145012354	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
511145012355	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145012356	Coenzyme A binding pocket [chemical binding]; other site
511145012357	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
511145012358	proposed active site lysine [active]
511145012359	conserved cys residue [active]
511145012360	Malate synthase A (MSA), present in some bacteria, plants and fungi. Prokaryotic MSAs tend to be monomeric, whereas eukaryotic enzymes are homomultimers. In general, malate synthase catalyzes the Claisen condensation of glyoxylate and acetyl-CoA to...; Region: malate_synt_A; cd00727
511145012361	active site
511145012362	Members of the ICL/PEPM enzyme family catalyze either P-C or C-C bond formation/cleavage. Known members are phosphoenolpyruvate mutase (PEPM), phosphonopyruvate hydrolase (PPH), carboxyPEP mutase (CPEP mutase), oxaloacetate hydrolase (OAH), isocitrate...; Region: ICL_PEPM; cd00377
511145012363	tetramer interface [polypeptide binding]; other site
511145012364	active site
511145012365	Mg2+/Mn2+ binding site [ion binding]; other site
511145012366	Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]; Region: COG4579
511145012367	ShET2 enterotoxin, N-terminal region; Region: Toxin_15; pfam07906
511145012368	ankyrin repeats;  ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other...; Region: ANK; cd00204
511145012369	transcriptional repressor IclR; Provisional; Region: PRK11569
511145012370	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145012371	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145012372	B12-dependent methionine synthase; Provisional; Region: metH; PRK09490
511145012373	Methionine synthase I (cobalamin-dependent), methyltransferase domain [Amino acid transport and metabolism]; Region: MetH; COG0646
511145012374	MeTr subgroup of pterin binding enzymes. This family includes cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  Cobalamin-dependent...; Region: MeTr; cd00740
511145012375	substrate binding pocket [chemical binding]; other site
511145012376	B12 binding domain of methionine synthase. This domain binds methylcobalamin, which it uses as an intermediate methyl carrier from methyltetrahydrofolate (CH3H4folate) to homocysteine (Hcy); Region: methionine_synthase_B12_BD; cd02069
511145012377	B12 binding site [chemical binding]; other site
511145012378	cobalt ligand [ion binding]; other site
511145012379	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
511145012380	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
511145012381	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
511145012382	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
511145012383	Type 1 glutamine amidotransferase (GATase1)-like domain found in peptidase E; Region: GAT1_Peptidase_E; cd03146
511145012384	active site pocket [active]
511145012385	oxyanion hole [active]
511145012386	catalytic triad [active]
511145012387	active site nucleophile [active]
511145012388	23S rRNA pseudouridine synthase F; Provisional; Region: PRK10475
511145012389	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
511145012390	RNA binding surface [nucleotide binding]; other site
511145012391	Pseudouridine synthase, Escherichia coli RluF like; Region: PseudoU_synth_RluF; cd02554
511145012392	probable active site [active]
511145012393	hypothetical protein; Provisional; Region: PRK10515
511145012394	aspartate kinase III; Validated; Region: PRK09084
511145012395	AAK_AKiii-LysC-EC: Amino Acid Kinase Superfamily (AAK), AKiii-LysC-EC: this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKIII. AKIII is a monofunctional class enzyme (LysC) found in some...; Region: AAK_AKiii-LysC-EC; cd04258
511145012396	nucleotide binding site [chemical binding]; other site
511145012397	putative catalytic residues [active]
511145012398	aspartate binding site [chemical binding]; other site
511145012399	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_1; cd04932
511145012400	lysine allosteric regulatory site; other site
511145012401	dimer interface [polypeptide binding]; other site
511145012402	ACT domains located C-terminal to the catalytic domain of the lysine-sensitive aspartokinase isoenzyme AKIII; Region: ACT_AKiii-LysC-EC_2; cd04917
511145012403	dimer interface [polypeptide binding]; other site
511145012404	glucose-6-phosphate isomerase; Reviewed; Region: pgi; PRK00179
511145012405	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
511145012406	active site
511145012407	dimer interface [polypeptide binding]; other site
511145012408	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
511145012409	dimer interface [polypeptide binding]; other site
511145012410	active site
511145012411	Exopolysaccharide production protein YjbE; Region: YjbE; pfam11106
511145012412	Group 4 capsule polysaccharide formation lipoprotein gfcB; Region: Cap_synth_GfcB; pfam11102
511145012413	Capsule biosynthesis GfcC; Region: Caps_synth_GfcC; pfam06251
511145012414	Bacterial putative lipoprotein (DUF940); Region: DUF940; pfam06082
511145012415	PTS system glucose-specific transporter subunits IIBC; Provisional; Region: PRK11089
511145012416	phosphate-starvation-inducible protein PsiE; Provisional; Region: PRK02833
511145012417	D-xylose transporter XylE; Provisional; Region: xylE; PRK10077
511145012418	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145012419	putative substrate translocation pore; other site
511145012420	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
511145012421	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145012422	dimer interface [polypeptide binding]; other site
511145012423	conserved gate region; other site
511145012424	putative PBP binding loops; other site
511145012425	ABC-ATPase subunit interface; other site
511145012426	maltose transporter membrane protein; Provisional; Region: malF; PRK10999
511145012427	Maltose transport system permease protein MalF P2 domain; Region: MalF_P2; pfam14785
511145012428	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
511145012429	dimer interface [polypeptide binding]; other site
511145012430	conserved gate region; other site
511145012431	putative PBP binding loops; other site
511145012432	ABC-ATPase subunit interface; other site
511145012433	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
511145012434	maltose ABC transporter periplasmic protein; Reviewed; Region: malE; PRK09474
511145012435	maltose/maltodextrin transporter ATP-binding protein; Provisional; Region: PRK11000
511145012436	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
511145012437	Walker A/P-loop; other site
511145012438	ATP binding site [chemical binding]; other site
511145012439	Q-loop/lid; other site
511145012440	ABC transporter signature motif; other site
511145012441	Walker B; other site
511145012442	D-loop; other site
511145012443	H-loop/switch region; other site
511145012444	TOBE domain; Region: TOBE_2; pfam08402
511145012445	maltoporin; Provisional; Region: lamB; PRK09360
511145012446	The Maltoporin-like channels (LamB porin) form a trimeric structure which facilitate the diffusion of maltodextrins and other sugars across the outer membrane of Gram-negative bacteria. The membrane channel is formed by an 18-strand antiparallel...; Region: Maltoporin-like; cd01346
511145012447	trimer interface; other site
511145012448	sugar binding site [chemical binding]; other site
511145012449	maltose regulon periplasmic protein; Provisional; Region: PRK10564
511145012450	chorismate pyruvate lyase; Provisional; Region: ubiC; PRK11655
511145012451	4-Hydroxybenzoate polyprenyltransferase; Region: PT_UbiA_COQ2; cd13959
511145012452	putative active site [active]
511145012453	Glycerol-3-phosphate O-acyltransferase [Lipid metabolism]; Region: PlsB; COG2937
511145012454	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Region: LPLAT_DHAPAT-like; cd07993
511145012455	putative acyl-acceptor binding pocket; other site
511145012456	Integral membrane diacylglycerol kinase; Region: DAGK_IM; cd14264
511145012457	putative active site [active]
511145012458	trimer interface [polypeptide binding]; other site
511145012459	putative active site [active]
511145012460	Zn binding site [ion binding]; other site
511145012461	LexA repressor; Validated; Region: PRK00215
511145012462	LexA DNA binding domain; Region: LexA_DNA_bind; pfam01726
511145012463	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
511145012464	Catalytic site [active]
511145012465	DNA-damage-inducible SOS response protein; Provisional; Region: PRK10367
511145012466	DinF and similar proteins, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_DinF_like; cd13136
511145012467	hypothetical protein; Provisional; Region: PRK10428
511145012468	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
511145012469	metal binding site 2 [ion binding]; metal-binding site
511145012470	putative DNA binding helix; other site
511145012471	metal binding site 1 [ion binding]; metal-binding site
511145012472	dimer interface [polypeptide binding]; other site
511145012473	structural Zn2+ binding site [ion binding]; other site
511145012474	Protein of unknown function (DUF2713); Region: DUF2713; pfam10897
511145012475	phage shock protein G; Reviewed; Region: pspG; PRK09459
511145012476	quinone oxidoreductase, NADPH-dependent; Provisional; Region: PRK10754
511145012477	Quinone oxidoreductase (QOR); Region: QOR2; cd05286
511145012478	NADP binding site [chemical binding]; other site
511145012479	dimer interface [polypeptide binding]; other site
511145012480	replicative DNA helicase; Provisional; Region: PRK08006
511145012481	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
511145012482	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
511145012483	Walker A motif; other site
511145012484	ATP binding site [chemical binding]; other site
511145012485	Walker B motif; other site
511145012486	DNA binding loops [nucleotide binding]
511145012487	alanine racemase; Reviewed; Region: alr; PRK00053
511145012488	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, Proteobacterial Alanine Racemases; Region: PLPDE_III_AR_proteobact; cd06827
511145012489	active site
511145012490	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
511145012491	substrate binding site [chemical binding]; other site
511145012492	catalytic residues [active]
511145012493	dimer interface [polypeptide binding]; other site
511145012494	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
511145012495	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145012496	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145012497	homodimer interface [polypeptide binding]; other site
511145012498	catalytic residue [active]
511145012499	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145012500	active site
511145012501	motif I; other site
511145012502	motif II; other site
511145012503	secondary thiamine-phosphate synthase enzyme; Region: TIGR00149_YjbQ
511145012504	Uncharacterized protein conserved in bacteria [Function unknown]; Region: MmcQ; COG2315
511145012505	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
511145012506	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
511145012507	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
511145012508	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
511145012509	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
511145012510	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
511145012511	dimer interface [polypeptide binding]; other site
511145012512	ssDNA binding site [nucleotide binding]; other site
511145012513	tetramer (dimer of dimers) interface [polypeptide binding]; other site
511145012514	putative single-stranded DNA-binding protein; Region: PHA01740
511145012515	Predicted signal transduction protein containing sensor and EAL domains [Signal transduction mechanisms]; Region: COG4943
511145012516	CSS motif domain associated with EAL; Region: CSS-motif; pfam12792
511145012517	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
511145012518	DNA-binding transcriptional regulator SoxS; Provisional; Region: PRK10219
511145012519	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012520	redox-sensitivie transcriptional activator SoxR; Provisional; Region: PRK15002
511145012521	Helix-Turn-Helix DNA binding domain of the SoxR transcription regulator; Region: HTH_SoxR; cd01110
511145012522	DNA binding residues [nucleotide binding]
511145012523	dimer interface [polypeptide binding]; other site
511145012524	[2Fe-2S] cluster binding site [ion binding]; other site
511145012525	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
511145012526	Sulfate transporter family; Region: Sulfate_transp; cl19250
511145012527	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
511145012528	Na+/H+ antiporter, bacterial form; Region: a_cpa1; TIGR00831
511145012529	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
511145012530	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
511145012531	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
511145012532	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
511145012533	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
511145012534	Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain; Region: SLC5sbd_u4; cd11480
511145012535	Na binding site [ion binding]; other site
511145012536	Predicted membrane protein [Function unknown]; Region: COG3162
511145012537	acetyl-CoA synthetase; Provisional; Region: PRK00174
511145012538	Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme); Region: ACS; cd05966
511145012539	active site
511145012540	CoA binding site [chemical binding]; other site
511145012541	acyl-activating enzyme (AAE) consensus motif; other site
511145012542	AMP binding site [chemical binding]; other site
511145012543	acetate binding site [chemical binding]; other site
511145012544	cytochrome c nitrite reductase subunit c552; Provisional; Region: nrfA; PRK11125
511145012545	cytochrome c nitrite reductase pentaheme subunit; Provisional; Region: PRK11659
511145012546	Cytochrome c7; Region: Cytochrome_C7; cl19206
511145012547	Cytochrome c3; Region: Cytochrom_c3_2; pfam14537
511145012548	cytochrome c nitrite reductase, Fe-S protein; Region: cyt_nit_nrfC; TIGR03149
511145012549	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145012550	4Fe-4S dicluster domain; Region: Fer4_11; pfam13247
511145012551	cytochrome c nitrite reductase, NrfD subunit; Region: cyt_nit_nrfD; TIGR03148
511145012552	heme lyase subunit NrfE; Provisional; Region: PRK10369
511145012553	formate-dependent nitrite reductase complex subunit NrfF; Provisional; Region: PRK10144
511145012554	formate-dependent nitrite reductase complex subunit NrfG; Provisional; Region: PRK10370
511145012555	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
511145012556	binding surface
511145012557	TPR motif; other site
511145012558	glutamate/aspartate:proton symporter; Provisional; Region: gltP; PRK11283
511145012559	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
511145012560	Sel1-like repeats; Region: SEL1; smart00671
511145012561	formate dehydrogenase, alpha subunit, archaeal-type; Region: Fdh-alpha; TIGR01591
511145012562	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_Formate-Dh-H; cd02753
511145012563	[4Fe-4S] binding site [ion binding]; other site
511145012564	molybdopterin cofactor binding site; other site
511145012565	Formate dehydrogenase H (Formate-Dh-H) catalyzes the reversible oxidation of formate to CO2 with the release of a proton and two electrons. It is a component of the anaerobic formate hydrogen lyase complex. The E. coli formate dehydrogenase H (Fdh-H) is...; Region: MopB_CT_Formate-Dh_H; cd02790
511145012566	molybdopterin cofactor binding site; other site
511145012567	putative outer membrane efflux protein MdtP; Provisional; Region: PRK09915
511145012568	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
511145012569	Outer membrane efflux protein; Region: OEP; pfam02321
511145012570	multidrug efflux system protein MdtO; Provisional; Region: PRK11427
511145012571	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
511145012572	multidrug resistance protein MdtN; Provisional; Region: PRK10476
511145012573	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
511145012574	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
511145012575	HlyD family secretion protein; Region: HlyD_3; pfam13437
511145012576	Alkyl sulfatase and related hydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2015
511145012577	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
511145012578	Alkyl sulfatase dimerization; Region: Alkyl_sulf_dimr; pfam14863
511145012579	Alkyl sulfatase C-terminal; Region: Alkyl_sulf_C; pfam14864
511145012580	D-allose kinase; Provisional; Region: PRK09698
511145012581	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
511145012582	nucleotide binding site [chemical binding]; other site
511145012583	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
511145012584	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
511145012585	substrate binding site [chemical binding]; other site
511145012586	hexamer interface [polypeptide binding]; other site
511145012587	metal binding site [ion binding]; metal-binding site
511145012588	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145012589	TM-ABC transporter signature motif; other site
511145012590	D-allose transporter ATP-binding protein; Provisional; Region: PRK09700
511145012591	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145012592	Walker A/P-loop; other site
511145012593	ATP binding site [chemical binding]; other site
511145012594	Q-loop/lid; other site
511145012595	ABC transporter signature motif; other site
511145012596	Walker B; other site
511145012597	D-loop; other site
511145012598	H-loop/switch region; other site
511145012599	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145012600	D-allose transporter subunit; Provisional; Region: PRK09701
511145012601	Periplasmic allose-binding domain of bacterial transport systems that function as a primary receptor of active transport and chemotaxis; Region: PBP1_allose_binding; cd06320
511145012602	ligand binding site [chemical binding]; other site
511145012603	dimerization interface [polypeptide binding]; other site
511145012604	zinc binding site [ion binding]; other site
511145012605	DNA-binding transcriptional repressor RpiR; Provisional; Region: PRK11337
511145012606	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
511145012607	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
511145012608	putative active site [active]
511145012609	ribose 5-phosphate isomerase B; Region: rpiB; TIGR01120
511145012610	carbon-phosphorus lyase complex accessory protein; Provisional; Region: phnP; PRK11244
511145012611	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145012612	Coenzyme A binding pocket [chemical binding]; other site
511145012613	ribose 1,5-bisphosphokinase; Provisional; Region: PRK10078
511145012614	Guanylate kinase; Region: Guanylate_kin; pfam00625
511145012615	active site
511145012616	Metal-dependent hydrolase involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: COG3454
511145012617	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
511145012618	PhnM is believed to be a subunit of the membrane associated C-P lyase complex. C-P lyase is thought to catalyze the direct cleavage of inactivated C-P bonds to yield inorganic phosphate and the corresponding hydrocarbons. It is responsible for cleavage...; Region: PhnM; cd01306
511145012619	active site
511145012620	ABC-type phosphonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: PhnL; COG4778
511145012621	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
511145012622	Walker A/P-loop; other site
511145012623	ATP binding site [chemical binding]; other site
511145012624	Q-loop/lid; other site
511145012625	ABC transporter signature motif; other site
511145012626	Walker B; other site
511145012627	D-loop; other site
511145012628	H-loop/switch region; other site
511145012629	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
511145012630	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
511145012631	Walker A/P-loop; other site
511145012632	ATP binding site [chemical binding]; other site
511145012633	Q-loop/lid; other site
511145012634	ABC transporter signature motif; other site
511145012635	Walker B; other site
511145012636	D-loop; other site
511145012637	H-loop/switch region; other site
511145012638	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
511145012639	Phosphonate metabolizm protein PhnJ; Region: PhnJ; pfam06007
511145012640	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnI; COG3626
511145012641	Uncharacterized enzyme of phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnH; COG3625
511145012642	Phosphonate metabolizm protein PhnG; Region: PhnG; pfam06754
511145012643	phosphonate metabolism transcriptional regulator PhnF; Provisional; Region: PRK10079
511145012644	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145012645	DNA-binding site [nucleotide binding]; DNA binding site
511145012646	UTRA domain; Region: UTRA; pfam07702
511145012647	phosphonate ABC transporter, periplasmic phosphonate binding protein; Region: PhnD; TIGR03431
511145012648	ABC-type phosphate/phosphonate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: PhnD; COG3221
511145012649	phosphonate/organophosphate ester transporter subunit; Provisional; Region: PRK09984
511145012650	ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Region: ABC_PhnC_transporter; cd03256
511145012651	Walker A/P-loop; other site
511145012652	ATP binding site [chemical binding]; other site
511145012653	Q-loop/lid; other site
511145012654	ABC transporter signature motif; other site
511145012655	Walker B; other site
511145012656	D-loop; other site
511145012657	H-loop/switch region; other site
511145012658	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
511145012659	dimer interface [polypeptide binding]; other site
511145012660	hypothetical protein; Provisional; Region: PRK10220
511145012661	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
511145012662	PhnA protein; Region: PhnA; pfam03831
511145012663	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
511145012664	G1 box; other site
511145012665	GTP/Mg2+ binding site [chemical binding]; other site
511145012666	G2 box; other site
511145012667	Switch I region; other site
511145012668	G3 box; other site
511145012669	Switch II region; other site
511145012670	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
511145012671	G2 box; other site
511145012672	Switch I region; other site
511145012673	G3 box; other site
511145012674	Switch II region; other site
511145012675	G4 box; other site
511145012676	G5 box; other site
511145012677	YjcZ-like protein; Region: YjcZ; pfam13990
511145012678	proline/glycine betaine transporter; Provisional; Region: PRK10642
511145012679	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145012680	putative substrate translocation pore; other site
511145012681	Osmosensory transporter coiled coil; Region: Osmo_CC; pfam08946
511145012682	sensor protein BasS/PmrB; Provisional; Region: PRK10755
511145012683	HAMP domain; Region: HAMP; pfam00672
511145012684	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145012685	dimer interface [polypeptide binding]; other site
511145012686	phosphorylation site [posttranslational modification]
511145012687	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145012688	ATP binding site [chemical binding]; other site
511145012689	Mg2+ binding site [ion binding]; other site
511145012690	G-X-G motif; other site
511145012691	DNA-binding transcriptional regulator BasR; Provisional; Region: PRK10643
511145012692	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145012693	active site
511145012694	phosphorylation site [posttranslational modification]
511145012695	intermolecular recognition site; other site
511145012696	dimerization interface [polypeptide binding]; other site
511145012697	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145012698	DNA binding site [nucleotide binding]
511145012699	putative metal dependent hydrolase; Provisional; Region: PRK11598
511145012700	Domain of unknown function (DUF1705); Region: DUF1705; pfam08019
511145012701	Sulfatase; Region: Sulfatase; pfam00884
511145012702	arginine:agmatin antiporter; Provisional; Region: PRK10644
511145012703	Spore germination protein; Region: Spore_permease; cl17796
511145012704	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145012705	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012706	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
511145012707	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012708	arginine decarboxylase; Provisional; Region: PRK15029
511145012709	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
511145012710	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
511145012711	homodimer interface [polypeptide binding]; other site
511145012712	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145012713	catalytic residue [active]
511145012714	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
511145012715	DNA-binding transcriptional regulator MelR; Provisional; Region: PRK10371
511145012716	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012717	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145012718	alpha-galactosidase; Provisional; Region: PRK15076
511145012719	Glycoside Hydrolases Family 4; Alpha-glucosidases and alpha-galactosidases; Region: GH4_alpha_glucosidase_galactosidase; cd05297
511145012720	NAD binding site [chemical binding]; other site
511145012721	sugar binding site [chemical binding]; other site
511145012722	divalent metal binding site [ion binding]; other site
511145012723	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
511145012724	dimer interface [polypeptide binding]; other site
511145012725	melibiose:sodium symporter; Provisional; Region: PRK10429
511145012726	sugar (Glycoside-Pentoside-Hexuronide) transporter; Region: gph; TIGR00792
511145012727	hypothetical protein; Provisional; Region: PRK09867
511145012728	fumarate hydratase FumB; Provisional; Region: PRK15391
511145012729	Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain [Energy production and conversion]; Region: TtdA; COG1951
511145012730	Fumarase C-terminus; Region: Fumerase_C; pfam05683
511145012731	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK12489
511145012732	DNA-binding transcriptional activator DcuR; Provisional; Region: PRK10430
511145012733	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145012734	active site
511145012735	phosphorylation site [posttranslational modification]
511145012736	intermolecular recognition site; other site
511145012737	dimerization interface [polypeptide binding]; other site
511145012738	sensory histidine kinase DcuS; Provisional; Region: PRK11086
511145012739	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
511145012740	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
511145012741	putative active site [active]
511145012742	heme pocket [chemical binding]; other site
511145012743	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
511145012744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145012745	ATP binding site [chemical binding]; other site
511145012746	Mg2+ binding site [ion binding]; other site
511145012747	G-X-G motif; other site
511145012748	Uncharacterized conserved protein [Function unknown]; Region: COG3592
511145012749	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145012750	Coenzyme A binding pocket [chemical binding]; other site
511145012751	Protein of unknown function (DUF2622); Region: DUF2622; pfam11080
511145012752	Protein of unknown function (DUF2566); Region: DUF2566; pfam10753
511145012753	lysyl-tRNA synthetase; Reviewed; Region: PRK12445
511145012754	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
511145012755	dimer interface [polypeptide binding]; other site
511145012756	putative anticodon binding site; other site
511145012757	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
511145012758	motif 1; other site
511145012759	active site
511145012760	motif 2; other site
511145012761	motif 3; other site
511145012762	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
511145012763	POT family; Region: PTR2; cl17359
511145012764	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145012765	putative substrate translocation pore; other site
511145012766	lysine decarboxylase CadA; Provisional; Region: PRK15400
511145012767	Orn/Lys/Arg decarboxylase, N-terminal domain; Region: OKR_DC_1_N; pfam03709
511145012768	Ornithine decarboxylase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to ornithine decarboxylase (ODC), arginine decarboxylase (ADC) and lysine...; Region: Orn_deC_like; cd00615
511145012769	homodimer interface [polypeptide binding]; other site
511145012770	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145012771	catalytic residue [active]
511145012772	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
511145012773	lysine/cadaverine antiporter; Provisional; Region: cadB; PRK10435
511145012774	DNA-binding transcriptional activator CadC; Provisional; Region: PRK10153
511145012775	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145012776	DNA binding site [nucleotide binding]
511145012777	putative transcriptional regulator; Provisional; Region: PRK11640
511145012778	Bacterial regulatory proteins, tetR family; Region: TetR_N; cl19382
511145012779	thiol:disulfide interchange protein precursor; Provisional; Region: dipZ; PRK00293
511145012780	Disulphide bond corrector protein DsbC; Region: DsbC; pfam11412
511145012781	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
511145012782	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
511145012783	DsbD alpha interface [polypeptide binding]; other site
511145012784	catalytic residues [active]
511145012785	divalent-cation tolerance protein CutA; Provisional; Region: PRK10645
511145012786	anaerobic C4-dicarboxylate transporter; Reviewed; Region: PRK09412
511145012787	aspartate ammonia-lyase; Provisional; Region: aspA; PRK12273
511145012788	Aspartase; Region: Aspartase; cd01357
511145012789	active sites [active]
511145012790	tetramer interface [polypeptide binding]; other site
511145012791	Protein affecting phage T7 exclusion by the F plasmid [General function prediction only]; Region: FxsA; COG3030
511145012792	putative transporter; Provisional; Region: PRK11021
511145012793	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145012794	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
511145012795	oligomerisation interface [polypeptide binding]; other site
511145012796	mobile loop; other site
511145012797	roof hairpin; other site
511145012798	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
511145012799	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
511145012800	ring oligomerisation interface [polypeptide binding]; other site
511145012801	ATP/Mg binding site [chemical binding]; other site
511145012802	stacking interactions; other site
511145012803	hinge regions; other site
511145012804	Domain of unknown function (DUF4156); Region: DUF4156; pfam13698
511145012805	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
511145012806	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145012807	FeS/SAM binding site; other site
511145012808	elongation factor P; Validated; Region: PRK00529
511145012809	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
511145012810	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
511145012811	RNA binding site [nucleotide binding]; other site
511145012812	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
511145012813	RNA binding site [nucleotide binding]; other site
511145012814	entericidin A; Provisional; Region: PRK09810
511145012815	entericidin B membrane lipoprotein; Provisional; Region: PRK10081
511145012816	multidrug efflux system protein; Provisional; Region: PRK11431
511145012817	outer membrane lipoprotein Blc; Provisional; Region: PRK10477
511145012818	beta-lactamase/D-alanine carboxypeptidase; Provisional; Region: ampC; PRK11289
511145012819	Quinol:fumarate reductase (QFR) Type D subfamily, 13kD hydrophobic subunit D; QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitD; cd00547
511145012820	Iron-sulfur protein interface; other site
511145012821	proximal quinone binding site [chemical binding]; other site
511145012822	C-subunit interface; other site
511145012823	distal quinone binding site; other site
511145012824	Quinol:fumarate reductase (QFR) Type D subfamily, 15kD hydrophobic subunit C;  QFR couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, the opposite reaction to that catalyzed by the related protein, succinate:quinine...; Region: QFR_TypeD_subunitC; cd00546
511145012825	D-subunit interface [polypeptide binding]; other site
511145012826	Iron-sulfur protein interface; other site
511145012827	proximal quinone binding site [chemical binding]; other site
511145012828	distal quinone binding site [chemical binding]; other site
511145012829	fumarate reductase iron-sulfur subunit; Provisional; Region: PRK12385
511145012830	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
511145012831	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
511145012832	fumarate reductase flavoprotein subunit; Validated; Region: PRK09231
511145012833	L-aspartate oxidase; Provisional; Region: PRK06175
511145012834	Fumarate reductase flavoprotein C-term; Region: Succ_DH_flav_C; pfam02910
511145012835	poxB regulator PoxA; Provisional; Region: PRK09350
511145012836	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
511145012837	motif 1; other site
511145012838	dimer interface [polypeptide binding]; other site
511145012839	active site
511145012840	motif 2; other site
511145012841	motif 3; other site
511145012842	inner membrane transporter YjeM; Provisional; Region: PRK15238
511145012843	Protein of unknown function (DUF2645); Region: DUF2645; pfam10840
511145012844	putative mechanosensitive channel protein; Provisional; Region: PRK10929
511145012845	linker histone 1 and histone 5 domains; the basic subunit of chromatin is the nucleosome, consisting of an octamer of core histones, two full turns of DNA, a linker histone (H1 or H5) and a variable length of linker DNA; H1/H5 are chromatin-associated...; Region: H15; cl00073
511145012846	DNA-binding site [nucleotide binding]; DNA binding site
511145012847	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
511145012848	Mechanosensitive ion channel inner membrane domain 1; Region: MscS_TM; pfam12794
511145012849	Mechanosensitive ion channel; Region: MS_channel; pfam00924
511145012850	phosphatidylserine decarboxylase; Reviewed; Region: psd; PRK00044
511145012851	GTPase RsgA; Reviewed; Region: PRK12288
511145012852	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
511145012853	RNA binding site [nucleotide binding]; other site
511145012854	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
511145012855	GTPase/Zn-binding domain interface [polypeptide binding]; other site
511145012856	GTP/Mg2+ binding site [chemical binding]; other site
511145012857	G4 box; other site
511145012858	G5 box; other site
511145012859	G1 box; other site
511145012860	Switch I region; other site
511145012861	G2 box; other site
511145012862	G3 box; other site
511145012863	Switch II region; other site
511145012864	DEDDh 3'-5' exonuclease domain of oligoribonuclease and similar proteins; Region: Orn; cd06135
511145012865	catalytic site [active]
511145012866	putative active site [active]
511145012867	putative substrate binding site [chemical binding]; other site
511145012868	dimer interface [polypeptide binding]; other site
511145012869	epoxyqueuosine reductase; Region: TIGR00276
511145012870	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
511145012871	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
511145012872	putative carbohydrate kinase; Provisional; Region: PRK10565
511145012873	yjeF N-terminal region; Region: yjeF_nterm; TIGR00197
511145012874	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
511145012875	putative substrate binding site [chemical binding]; other site
511145012876	putative ATP binding site [chemical binding]; other site
511145012877	ADP-binding protein; Provisional; Region: PRK10646
511145012878	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
511145012879	N-acetylmuramoyl-l-alanine amidase II; Provisional; Region: PRK10431
511145012880	AMIN domain; Region: AMIN; pfam11741
511145012881	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
511145012882	active site
511145012883	metal binding site [ion binding]; metal-binding site
511145012884	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
511145012885	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145012886	ATP binding site [chemical binding]; other site
511145012887	Mg2+ binding site [ion binding]; other site
511145012888	G-X-G motif; other site
511145012889	MutL_Trans_MutL: transducer domain, having a ribosomal S5 domain 2-like fold, found in proteins similar to Escherichia coli MutL.  EcMutL belongs to the DNA mismatch repair (MutL/MLH1/PMS2) family.  This transducer domain is homologous to the second...; Region: MutL_Trans_MutL; cd03482
511145012890	ATP binding site [chemical binding]; other site
511145012891	MutL C terminal dimerization domain; Region: MutL_C; pfam08676
511145012892	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
511145012893	bacterial Hfq-like; Region: Hfq; cd01716
511145012894	hexamer interface [polypeptide binding]; other site
511145012895	Sm1 motif; other site
511145012896	RNA binding site [nucleotide binding]; other site
511145012897	Sm2 motif; other site
511145012898	GTPase HflX; Provisional; Region: PRK11058
511145012899	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
511145012900	HflX GTPase family; Region: HflX; cd01878
511145012901	G1 box; other site
511145012902	GTP/Mg2+ binding site [chemical binding]; other site
511145012903	Switch I region; other site
511145012904	G2 box; other site
511145012905	G3 box; other site
511145012906	Switch II region; other site
511145012907	G4 box; other site
511145012908	G5 box; other site
511145012909	FtsH protease regulator HflK; Provisional; Region: PRK10930
511145012910	Bacterial membrane protein N terminal; Region: HflK_N; pfam12221
511145012911	High frequency of lysogenization K (HflK) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflK; cd03404
511145012912	HflC protein; Region: hflC; TIGR01932
511145012913	High frequency of lysogenization C (HflC) family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_HflC; cd03405
511145012914	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3242
511145012915	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
511145012916	GDP-binding site [chemical binding]; other site
511145012917	ACT binding site; other site
511145012918	IMP binding site; other site
511145012919	transcriptional repressor NsrR; Provisional; Region: PRK11014
511145012920	Rrf2 family protein; Region: rrf2_super; TIGR00738
511145012921	exoribonuclease R; Provisional; Region: PRK11642
511145012922	Ribonuclease R winged-helix domain; Region: HTH_12; pfam08461
511145012923	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
511145012924	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
511145012925	This domain is the catalytic domain of ribonuclease II; Region: RNB; smart00955
511145012926	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
511145012927	RNA binding site [nucleotide binding]; other site
511145012928	23S rRNA (guanosine-2'-O-)-methyltransferase; Provisional; Region: PRK11181
511145012929	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
511145012930	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
511145012931	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3789
511145012932	PspA/IM30 family; Region: PspA_IM30; pfam04012
511145012933	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
511145012934	Protein of unknown function (DUF2491); Region: DUF2491; pfam10679
511145012935	Predicted membrane protein [Function unknown]; Region: COG3766
511145012936	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
511145012937	Domain of Unknown Function (DUF350); Region: DUF350; pfam03994
511145012938	Predicted integral membrane protein [Function unknown]; Region: COG5463
511145012939	Glutathionylspermidine synthase [Amino acid transport and metabolism]; Region: Gsp; COG0754
511145012940	isovaleryl CoA dehydrogenase; Provisional; Region: PRK11561
511145012941	Proteins involved in DNA damage response, similar to the AidB gene product; Region: AidB; cd01154
511145012942	FAD binding site [chemical binding]; other site
511145012943	substrate binding site [chemical binding]; other site
511145012944	catalytic residues [active]
511145012945	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145012946	putative biofilm stress and motility protein A; Provisional; Region: PRK14864
511145012947	esterase; Provisional; Region: PRK10566
511145012948	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
511145012949	transcriptional repressor UlaR; Provisional; Region: PRK13509
511145012950	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145012951	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145012952	putative L-ascorbate 6-phosphate lactonase; Provisional; Region: PRK11709
511145012953	Uncharacterized protein conserved in bacteria [Function unknown]; Region: SgaT; COG3037
511145012954	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
511145012955	active site
511145012956	P-loop; other site
511145012957	phosphorylation site [posttranslational modification]
511145012958	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145012959	active site
511145012960	phosphorylation site [posttranslational modification]
511145012961	3-Keto-L-gulonate 6-phosphate decarboxylase (KGPDC) and D-arabino-3-hexulose-6-phosphate synthase (HPS). KGPDC catalyzes the formation of L-xylulose 5-phosphate and carbon dioxide from 3-keto-L-gulonate 6-phosphate as part of the anaerobic pathway for...; Region: KGPDC_HPS; cd04726
511145012962	active site
511145012963	dimer interface [polypeptide binding]; other site
511145012964	magnesium binding site [ion binding]; other site
511145012965	L-xylulose 5-phosphate 3-epimerase; Reviewed; Region: PRK13209
511145012966	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
511145012967	AP (apurinic/apyrimidinic) site pocket; other site
511145012968	DNA interaction; other site
511145012969	Metal-binding active site; metal-binding site
511145012970	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
511145012971	intersubunit interface [polypeptide binding]; other site
511145012972	active site
511145012973	Zn2+ binding site [ion binding]; other site
511145012974	Protein of unknown function (DUF1471); Region: DUF1471; pfam07338
511145012975	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
511145012976	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
511145012977	dimer interface [polypeptide binding]; other site
511145012978	ssDNA binding site [nucleotide binding]; other site
511145012979	tetramer (dimer of dimers) interface [polypeptide binding]; other site
511145012980	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
511145012981	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
511145012982	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
511145012983	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
511145012984	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
511145012985	Cell envelope opacity-associated protein A [Cell envelope biogenesis, outer membrane]; Region: OapA; COG3061
511145012986	Opacity-associated protein A N-terminal motif; Region: OapA_N; pfam08525
511145012987	Opacity-associated protein A LysM-like domain; Region: OapA; pfam04225
511145012988	peptidyl-prolyl cis-trans isomerase; Provisional; Region: PRK11570
511145012989	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
511145012990	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
511145012991	D-alanine/D-serine/glycine permease; Provisional; Region: PRK11049
511145012992	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
511145012993	iron-sulfur cluster repair di-iron protein; Provisional; Region: PRK10992
511145012994	Domain of Unknown function (DUF542); Region: ScdA_N; pfam04405
511145012995	Hemerythrin-like domain; Region: Hr-like; cd12108
511145012996	Fe binding site [ion binding]; other site
511145012997	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
511145012998	EamA-like transporter family; Region: EamA; pfam00892
511145012999	Predicted nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG0702
511145013000	triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs; Region: TMR_SDR_a; cd05269
511145013001	NADP binding site [chemical binding]; other site
511145013002	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
511145013003	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Reviewed; Region: cpdB; PRK09420
511145013004	Escherichia coli CpdB and related proteins, N-terminal metallophosphatase domain; Region: MPP_CpdB_N; cd07410
511145013005	active site
511145013006	metal binding site [ion binding]; metal-binding site
511145013007	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
511145013008	CysQ, a 3'-Phosphoadenosine-5'-phosphosulfate (PAPS) 3'-phosphatase, is a bacterial member of the inositol monophosphatase family. It has been proposed that CysQ helps control intracellular levels of PAPS, which is an intermediate in...; Region: CysQ; cd01638
511145013009	active site
511145013010	Predicted transcriptional regulator [General function prediction only]; Region: COG3054
511145013011	Protein of unknown function (DUF1107); Region: DUF1107; pfam06526
511145013012	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
511145013013	Domain of unknown function DUF21; Region: DUF21; pfam01595
511145013014	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
511145013015	Transporter associated domain; Region: CorC_HlyC; smart01091
511145013016	methionine sulfoxide reductase A; Provisional; Region: PRK00058
511145013017	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: COG0729
511145013018	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145013019	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
511145013020	Surface antigen; Region: Bac_surface_Ag; pfam01103
511145013021	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2911
511145013022	AsmA-like C-terminal region; Region: AsmA_2; pfam13502
511145013023	Family of unknown function (DUF490); Region: DUF490; pfam04357
511145013024	GGCT-like domains, also called AIG2-like family. Gamma-glutamyl cyclotransferase (GGCT) catalyzes the formation of pyroglutamic acid (5-oxoproline) from dipeptides containing gamma-glutamyl, and is a dimeric protein. In Homo sapiens, the protein is...; Region: GGCT_like; cd06661
511145013025	putative active site pocket [active]
511145013026	dimerization interface [polypeptide binding]; other site
511145013027	putative catalytic residue [active]
511145013028	antitoxin ChpS; Provisional; Region: PRK11347
511145013029	toxin ChpB; Provisional; Region: PRK09812
511145013030	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
511145013031	dimer interface [polypeptide binding]; other site
511145013032	substrate binding site [chemical binding]; other site
511145013033	metal binding sites [ion binding]; metal-binding site
511145013034	Periplasmic binding domain of ABC-type YtfQ-like transport systems; Region: PBP1_YtfQ_like; cd06309
511145013035	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
511145013036	putative ligand binding site [chemical binding]; other site
511145013037	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
511145013038	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
511145013039	Walker A/P-loop; other site
511145013040	ATP binding site [chemical binding]; other site
511145013041	Q-loop/lid; other site
511145013042	ABC transporter signature motif; other site
511145013043	Walker B; other site
511145013044	D-loop; other site
511145013045	H-loop/switch region; other site
511145013046	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
511145013047	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145013048	TM-ABC transporter signature motif; other site
511145013049	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
511145013050	TM-ABC transporter signature motif; other site
511145013051	Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate  into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1; Region: FBPase; cd00354
511145013052	AMP binding site [chemical binding]; other site
511145013053	metal binding site [ion binding]; metal-binding site
511145013054	active site
511145013055	UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Region: mpl; TIGR01081
511145013056	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
511145013057	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
511145013058	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
511145013059	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3028
511145013060	peptidase PmbA; Provisional; Region: PRK11040
511145013061	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
511145013062	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145013063	FeS/SAM binding site; other site
511145013064	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK09263
511145013065	ATP cone domain; Region: ATP-cone; pfam03477
511145013066	Class III ribonucleotide reductase; Region: RNR_III; cd01675
511145013067	effector binding site; other site
511145013068	active site
511145013069	Zn binding site [ion binding]; other site
511145013070	glycine loop; other site
511145013071	trehalose-6-phosphate hydrolase; Provisional; Region: PRK10933
511145013072	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
511145013073	Ca binding site [ion binding]; other site
511145013074	active site
511145013075	catalytic site [active]
511145013076	Domain of unknown function (DUF3459); Region: DUF3459; pfam11941
511145013077	PTS system trehalose(maltose)-specific transporter subunits IIBC; Provisional; Region: PRK11007
511145013078	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
511145013079	active site turn [active]
511145013080	phosphorylation site [posttranslational modification]
511145013081	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
511145013082	trehalose repressor; Provisional; Region: treR; PRK09492
511145013083	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145013084	DNA binding site [nucleotide binding]
511145013085	domain linker motif; other site
511145013086	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
511145013087	dimerization interface [polypeptide binding]; other site
511145013088	ligand binding site [chemical binding]; other site
511145013089	magnesium-transporting ATPase MgtA; Provisional; Region: PRK10517
511145013090	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
511145013091	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
511145013092	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
511145013093	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145013094	motif II; other site
511145013095	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
511145013096	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
511145013097	homotrimer interaction site [polypeptide binding]; other site
511145013098	putative active site [active]
511145013099	aspartate carbamoyltransferase regulatory subunit; Reviewed; Region: PRK00893
511145013100	Aspartate carbamoyltransferase regulatory chain, allosteric domain; Region: PyrI; pfam01948
511145013101	Aspartate carbamoyltransferase regulatory chain, metal binding domain; Region: PyrI_C; pfam02748
511145013102	aspartate carbamoyltransferase; Region: asp_carb_tr; TIGR00670
511145013103	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
511145013104	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
511145013105	PyrBI operon leader peptide; Region: PyrBI_leader; pfam08052
511145013106	YjgH belongs to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgH_like; cd02198
511145013107	homotrimer interaction site [polypeptide binding]; other site
511145013108	putative active site [active]
511145013109	oxidoreductase; Provisional; Region: PRK12742
511145013110	classical (c) SDRs; Region: SDR_c; cd05233
511145013111	NAD(P) binding site [chemical binding]; other site
511145013112	active site
511145013113	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
511145013114	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
511145013115	uncharacterized protein, YhcH/YjgK/YiaL family; Region: TIGR00022
511145013116	SopA-like central domain; Region: SopA; pfam13981
511145013117	ornithine carbamoyltransferase subunit I; Provisional; Region: PRK03515
511145013118	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
511145013119	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
511145013120	RNase E inhibitor protein; Provisional; Region: PRK11191
511145013121	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
511145013122	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145013123	Coenzyme A binding pocket [chemical binding]; other site
511145013124	Predicted membrane protein [Function unknown]; Region: COG4269
511145013125	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
511145013126	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
511145013127	active site
511145013128	HIGH motif; other site
511145013129	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
511145013130	KMSKS motif; other site
511145013131	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
511145013132	tRNA binding surface [nucleotide binding]; other site
511145013133	anticodon binding site; other site
511145013134	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
511145013135	DNA polymerase III subunit chi; Validated; Region: PRK05728
511145013136	multifunctional aminopeptidase A; Provisional; Region: PRK00913
511145013137	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
511145013138	interface (dimer of trimers) [polypeptide binding]; other site
511145013139	Substrate-binding/catalytic site; other site
511145013140	Zn-binding sites [ion binding]; other site
511145013141	lipopolysaccharide ABC transporter permease LptF; Provisional; Region: PRK15120
511145013142	lipopolysaccharide ABC transporter permease; Provisional; Region: PRK15071
511145013143	Bacterial protein of unknown function (DUF853); Region: DUF853; pfam05872
511145013144	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145013145	Walker A motif; other site
511145013146	ATP binding site [chemical binding]; other site
511145013147	gluconate operon transcriptional regulator; Provisional; Region: PRK14987
511145013148	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
511145013149	DNA binding site [nucleotide binding]
511145013150	domain linker motif; other site
511145013151	Ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_GntR; cd01575
511145013152	putative dimerization interface [polypeptide binding]; other site
511145013153	putative ligand binding site [chemical binding]; other site
511145013154	gluconate transporter; Region: gntP; TIGR00791
511145013155	GntP family permease; Region: GntP_permease; pfam02447
511145013156	gluconate 5-dehydrogenase; Provisional; Region: PRK07097
511145013157	gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; Region: Ga5DH-like_SDR_c; cd05347
511145013158	NADP binding site [chemical binding]; other site
511145013159	homodimer interface [polypeptide binding]; other site
511145013160	active site
511145013161	L-idonate 5-dehydrogenase; Provisional; Region: PRK09880
511145013162	L-idonate 5-dehydrogenase; Region: idonate-5-DH; cd08232
511145013163	putative NAD(P) binding site [chemical binding]; other site
511145013164	catalytic Zn binding site [ion binding]; other site
511145013165	Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits; Region: GntK; cd02021
511145013166	AAA domain; Region: AAA_33; pfam13671
511145013167	ATP-binding site [chemical binding]; other site
511145013168	Gluconate-6-phosphate binding site [chemical binding]; other site
511145013169	Zn-dependent alcohol dehydrogenases [General function prediction only]; Region: AdhP; COG1064
511145013170	Cinnamyl alcohol dehydrogenases (CAD); Region: CAD1; cd05283
511145013171	putative NAD(P) binding site [chemical binding]; other site
511145013172	putative substrate binding site [chemical binding]; other site
511145013173	catalytic Zn binding site [ion binding]; other site
511145013174	structural Zn binding site [ion binding]; other site
511145013175	dimer interface [polypeptide binding]; other site
511145013176	IS2 repressor TnpA; Reviewed; Region: PRK09413
511145013177	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
511145013178	IS2 transposase TnpB; Reviewed; Region: PRK09409
511145013179	HTH-like domain; Region: HTH_21; pfam13276
511145013180	Integrase core domain; Region: rve; pfam00665
511145013181	Integrase core domain; Region: rve_3; pfam13683
511145013182	IS66 C-terminal element; Region: DDE_Tnp_IS66_C; pfam13817
511145013183	Insertion element 4 transposase N-terminal; Region: Nterm_IS4; pfam13006
511145013184	FOG: Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3385
511145013185	Transposase DDE domain; Region: DDE_Tnp_1; pfam01609
511145013186	putative sialic acid transporter; Provisional; Region: PRK12307
511145013187	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145013188	putative substrate translocation pore; other site
511145013189	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
511145013190	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
511145013191	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
511145013192	Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair]; Region: Tra8; COG2826
511145013193	Helix-turn-helix domain; Region: HTH_38; pfam13936
511145013194	Homeodomain-like domain; Region: HTH_32; pfam13565
511145013195	Integrase core domain; Region: rve; pfam00665
511145013196	iron-dicitrate transporter ATP-binding subunit; Provisional; Region: fecE; PRK11231
511145013197	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
511145013198	Walker A/P-loop; other site
511145013199	ATP binding site [chemical binding]; other site
511145013200	Q-loop/lid; other site
511145013201	ABC transporter signature motif; other site
511145013202	Walker B; other site
511145013203	D-loop; other site
511145013204	H-loop/switch region; other site
511145013205	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145013206	ABC-ATPase subunit  interface; other site
511145013207	dimer interface [polypeptide binding]; other site
511145013208	putative PBP binding regions; other site
511145013209	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
511145013210	ABC-ATPase subunit  interface; other site
511145013211	dimer interface [polypeptide binding]; other site
511145013212	putative PBP binding regions; other site
511145013213	ABC-type Fe3+-citrate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FecB; COG4594
511145013214	Fe3+-siderophore binding domain FhuD.  These proteins have been shown to function as initial receptors in ABC transport of Fe3+-siderophores in many eubacterial species. They belong to the TroA-like superfamily of helical backbone metal receptor proteins...; Region: FhuD; cd01146
511145013215	siderophore binding site; other site
511145013216	Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; Region: FecA; COG4772
511145013217	Secretin and TonB N terminus short domain; Region: STN; smart00965
511145013218	TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel; Region: ligand_gated_channel; cd01347
511145013219	N-terminal plug; other site
511145013220	ligand-binding site [chemical binding]; other site
511145013221	fec operon regulator FecR; Reviewed; Region: PRK09774
511145013222	FecR protein; Region: FecR; pfam04773
511145013223	RNA polymerase sigma factor FecI; Provisional; Region: PRK09651
511145013224	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
511145013225	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
511145013226	DNA binding residues [nucleotide binding]
511145013227	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
511145013228	InsA N-terminal domain; Region: Zn_Tnp_IS1; pfam03811
511145013229	InsA C-terminal domain; Region: HTH_Tnp_IS1; pfam12759
511145013230	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
511145013231	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
511145013232	DNA binding residues [nucleotide binding]
511145013233	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
511145013234	gluconate transporter; Region: gntP; TIGR00791
511145013235	GntP family permease; Region: GntP_permease; pfam02447
511145013236	putative dehydratase; Provisional; Region: PRK08211
511145013237	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
511145013238	inhibitor site; inhibition site
511145013239	active site
511145013240	dimer interface [polypeptide binding]; other site
511145013241	catalytic residue [active]
511145013242	helix_turn_helix isocitrate lyase regulation; Region: HTH_ICLR; smart00346
511145013243	Transcriptional regulator [Transcription]; Region: IclR; COG1414
511145013244	Bacterial transcriptional regulator; Region: IclR; pfam01614
511145013245	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
511145013246	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; pfam08220
511145013247	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
511145013248	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
511145013249	substrate binding site [chemical binding]; other site
511145013250	hexamer interface [polypeptide binding]; other site
511145013251	metal binding site [ion binding]; metal-binding site
511145013252	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
511145013253	active site
511145013254	phosphorylation site [posttranslational modification]
511145013255	membrane complex biogenesis protein, BtpA family; Region: thylakoid_BtpA; TIGR00259
511145013256	PTS system, galactitol-specific IIC component; Region: EIIC-GAT; TIGR00827
511145013257	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
511145013258	active site
511145013259	P-loop; other site
511145013260	phosphorylation site [posttranslational modification]
511145013261	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
511145013262	oligomer interface [polypeptide binding]; other site
511145013263	active site
511145013264	metal binding site [ion binding]; metal-binding site
511145013265	Methyltransferase domain; Region: Methyltransf_31; pfam13847
511145013266	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145013267	S-adenosylmethionine binding site [chemical binding]; other site
511145013268	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
511145013269	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
511145013270	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145013271	Coenzyme A binding pocket [chemical binding]; other site
511145013272	hypothetical protein; Provisional; Region: PRK13687
511145013273	Domain of unknown function (DUF303); Region: DUF303; pfam03629
511145013274	N-acetylneuraminic acid mutarotase; Provisional; Region: PRK14131
511145013275	Kelch motif; Region: Kelch_1; pfam01344
511145013276	Oligogalacturonate-specific porin protein (KdgM); Region: KdgM; cl11629
511145013277	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
511145013278	Int/Topo IB signature motif; other site
511145013279	FimB and FimE and related proteins, DNA breaking-rejoining enzymes, integrase/recombinases, catalytic domain. This CD includes those proteins similar to E.coli FimE and FimB regulatory proteins and Proteus mirabilis MrpI; Region: INT_FimBE_C; cd01197
511145013280	Int/Topo IB signature motif; other site
511145013281	Fimbrial protein; Region: Fimbrial; cl01416
511145013282	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145013283	fimbrial chaperone protein FimC; Provisional; Region: PRK15195
511145013284	Pili and flagellar-assembly chaperone, PapD N-terminal domain; Region: PapD_N; pfam00345
511145013285	Pili assembly chaperone PapD, C-terminal domain; Region: PapD_C; pfam02753
511145013286	P pilus assembly protein, porin PapC [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimD; COG3188
511145013287	PapC N-terminal domain; Region: PapC_N; pfam13954
511145013288	Outer membrane usher protein; Region: Usher; pfam00577
511145013289	PapC C-terminal domain; Region: PapC_C; pfam13953
511145013290	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145013291	P pilus assembly protein, pilin FimA [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FimA; COG3539
511145013292	Mannose binding  domain of FimH and related proteins; Region: FimH_man-bind; cd10466
511145013293	mannosyl binding site [chemical binding]; other site
511145013294	Fimbrial protein; Region: Fimbrial; pfam00419
511145013295	fructuronate transporter; Provisional; Region: PRK10034
511145013296	GntP family permease; Region: GntP_permease; pfam02447
511145013297	mannonate dehydratase; Region: uxuA; TIGR00695
511145013298	mannonate dehydratase; Provisional; Region: PRK03906
511145013299	D-mannonate oxidoreductase; Provisional; Region: PRK15037
511145013300	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
511145013301	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
511145013302	DNA-binding transcriptional repressor UxuR; Provisional; Region: PRK10225
511145013303	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145013304	DNA-binding site [nucleotide binding]; DNA binding site
511145013305	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145013306	Protein of unknown function (DUF2686); Region: DUF2686; pfam10887
511145013307	DNA replication/recombination/repair protein; Provisional; Region: iraD; PRK14128
511145013308	cell density-dependent motility repressor; Provisional; Region: PRK10082
511145013309	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
511145013310	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
511145013311	dimerization interface [polypeptide binding]; other site
511145013312	Isoaspartyl dipeptidase hydrolyzes the beta-L-isoaspartyl linkages in dipeptides, as part of the degradative pathway to eliminate proteins with beta-L-isoaspartyl peptide bonds, bonds whereby the beta-group of an aspartate forms the peptide link with the...; Region: Isoaspartyl-dipeptidase; cd01308
511145013313	isoaspartyl dipeptidase IadA; Region: isoAsp_dipep; TIGR01975
511145013314	dimer interface [polypeptide binding]; other site
511145013315	active site
511145013316	hypothetical protein; Provisional; Region: PRK10519
511145013317	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
511145013318	Nucleoside recognition; Region: Gate; pfam07670
511145013319	RNA:NAD 2'-phosphotransferase [Translation, ribosomal structure and biogenesis]; Region: KptA; COG1859
511145013320	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145013321	Major Facilitator Superfamily; Region: MFS_1; pfam07690
511145013322	putative substrate translocation pore; other site
511145013323	SdiA-regulated; Region: SdiA-regulated; cd09971
511145013324	putative active site [active]
511145013325	CoA-substrate-specific enzyme activase, putative; Region: CoA_E_activ; TIGR00241
511145013326	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
511145013327	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
511145013328	Predicted membrane protein [Function unknown]; Region: COG2733
511145013329	Protein of unknown function (DUF445); Region: DUF445; pfam04286
511145013330	multidrug efflux system protein MdtM; Provisional; Region: PRK15403
511145013331	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145013332	putative substrate translocation pore; other site
511145013333	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
511145013334	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
511145013335	DNA-binding site [nucleotide binding]; DNA binding site
511145013336	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
511145013337	pyridoxal 5'-phosphate binding site [chemical binding]; other site
511145013338	homodimer interface [polypeptide binding]; other site
511145013339	catalytic residue [active]
511145013340	Uncharacterized conserved small protein [Function unknown]; Region: COG5457
511145013341	5-methylcytosine-specific restriction enzyme subunit McrC; Provisional; Region: PRK09736
511145013342	5-methylcytosine-specific restriction enzyme subunit McrB; Provisional; Region: PRK11331
511145013343	Domain of unknown function (DUF3578); Region: DUF3578; pfam12102
511145013344	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145013345	Walker A motif; other site
511145013346	ATP binding site [chemical binding]; other site
511145013347	Walker B motif; other site
511145013348	arginine finger; other site
511145013349	endoribonuclease SymE; Provisional; Region: PRK13605
511145013350	EcoKI restriction-modification system protein HsdS; Provisional; Region: PRK09737
511145013351	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
511145013352	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
511145013353	HsdM N-terminal domain; Region: HsdM_N; pfam12161
511145013354	N-6 DNA Methylase; Region: N6_Mtase; pfam02384
511145013355	Methyltransferase domain; Region: Methyltransf_26; pfam13659
511145013356	type I restriction enzyme EcoKI subunit R; Provisional; Region: hsdR; PRK11448
511145013357	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
511145013358	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
511145013359	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
511145013360	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
511145013361	ATP binding site [chemical binding]; other site
511145013362	putative Mg++ binding site [ion binding]; other site
511145013363	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
511145013364	nucleotide binding region [chemical binding]; other site
511145013365	ATP-binding site [chemical binding]; other site
511145013366	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
511145013367	Restriction endonuclease [Defense mechanisms]; Region: Mrr; COG1715
511145013368	Mrr N-terminal domain; Region: Mrr_N; pfam14338
511145013369	Restriction endonuclease; Region: Mrr_cat; pfam04471
511145013370	putative GTP-binding protein YjiA; Provisional; Region: PRK11537
511145013371	The function of this protein family is unkown. The amino acid sequence of YjiA protein in E. coli contains several conserved motifs that characterizes it as a P-loop GTPase. YijA gene is among the genes significantly induced in response to DNA-damage...; Region: CobW_like; cd03112
511145013372	P-loop, Walker A motif; other site
511145013373	Base recognition motif; other site
511145013374	Cobalamin synthesis protein cobW C-terminal domain; Region: CobW_C; pfam07683
511145013375	Uncharacterized small protein [Function unknown]; Region: COG2879
511145013376	carbon starvation protein A; Provisional; Region: PRK15015
511145013377	Carbon starvation protein CstA; Region: CstA; pfam02554
511145013378	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
511145013379	methyl-accepting chemotaxis protein I; Provisional; Region: PRK15041
511145013380	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cd00181
511145013381	dimer interface [polypeptide binding]; other site
511145013382	ligand binding site [chemical binding]; other site
511145013383	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145013384	dimerization interface [polypeptide binding]; other site
511145013385	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cd11386
511145013386	dimer interface [polypeptide binding]; other site
511145013387	putative CheW interface [polypeptide binding]; other site
511145013388	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
511145013389	D-galactonate transporter; Region: 2A0114; TIGR00893
511145013390	putative substrate translocation pore; other site
511145013391	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
511145013392	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
511145013393	DNA-binding site [nucleotide binding]; DNA binding site
511145013394	Transcriptional regulators [Transcription]; Region: GntR; COG1802
511145013395	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
511145013396	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
511145013397	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH7; cd08261
511145013398	putative NAD(P) binding site [chemical binding]; other site
511145013399	catalytic Zn binding site [ion binding]; other site
511145013400	structural Zn binding site [ion binding]; other site
511145013401	phosphoglycerol transferase I; Provisional; Region: PRK03776
511145013402	Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane]; Region: MdoB; COG1368
511145013403	hypothetical protein; Provisional; Region: PRK11667
511145013404	DNA replication protein DnaC; Validated; Region: PRK07952
511145013405	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
511145013406	Walker A motif; other site
511145013407	ATP binding site [chemical binding]; other site
511145013408	Walker B motif; other site
511145013409	primosomal protein DnaI; Provisional; Region: PRK02854
511145013410	hypothetical protein; Provisional; Region: PRK09917
511145013411	Uncharacterized conserved protein [Function unknown]; Region: COG2966
511145013412	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
511145013413	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
511145013414	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145013415	DNA binding residues [nucleotide binding]
511145013416	dimerization interface [polypeptide binding]; other site
511145013417	DNA-binding transcriptional activator BglJ; Provisional; Region: PRK11475
511145013418	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
511145013419	DNA binding residues [nucleotide binding]
511145013420	dimerization interface [polypeptide binding]; other site
511145013421	ferric iron reductase involved in ferric hydroximate transport; Provisional; Region: PRK10647
511145013422	Ferric iron reductase FhuF-like transporter; Region: FhuF; pfam06276
511145013423	FhuF 2Fe-2S C-terminal domain; Region: FhuF_C; pfam11575
511145013424	Protein of unknown function (DUF1435); Region: DUF1435; pfam07256
511145013425	16S ribosomal RNA m2G1207 methyltransferase; Provisional; Region: rsmC; PRK09489
511145013426	Methyltransferase small domain N-terminal; Region: MTS_N; pfam08468
511145013427	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
511145013428	S-adenosylmethionine binding site [chemical binding]; other site
511145013429	DNA polymerase III subunit psi; Validated; Region: PRK06856
511145013430	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
511145013431	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
511145013432	Coenzyme A binding pocket [chemical binding]; other site
511145013433	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
511145013434	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145013435	motif II; other site
511145013436	peptide chain release factor 3; Provisional; Region: prfC; PRK00741
511145013437	Release Factor 3 (RF3) protein involved in the terminal step of translocation in bacteria; Region: RF3; cd04169
511145013438	G1 box; other site
511145013439	putative GEF interaction site [polypeptide binding]; other site
511145013440	GTP/Mg2+ binding site [chemical binding]; other site
511145013441	Switch I region; other site
511145013442	G2 box; other site
511145013443	G3 box; other site
511145013444	Switch II region; other site
511145013445	G4 box; other site
511145013446	G5 box; other site
511145013447	RF3_II: this subfamily represents the domain II of bacterial Release Factor 3 (RF3). Termination of protein synthesis by the ribosome requires two release factor (RF) classes. The class II RF3 is a GTPase that removes class I RFs (RF1 or RF2) from the...; Region: RF3_II; cd03689
511145013448	Elongation Factor G, domain II; Region: EFG_II; pfam14492
511145013449	periplasmic protein; Provisional; Region: PRK10568
511145013450	BON domain; Region: BON; pfam04972
511145013451	BON domain; Region: BON; pfam04972
511145013452	Small integral membrane protein [Function unknown]; Region: COG5487
511145013453	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: COG4667
511145013454	Hypothetical patatin similar to yjju protein of Escherichia coli; Region: Pat_hypo_Ecoli_yjju_like; cd07208
511145013455	active site
511145013456	nucleophile elbow; other site
511145013457	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
511145013458	active site
511145013459	glycine radical enzyme activase, YjjW family; Region: activase_YjjW; TIGR04041
511145013460	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
511145013461	FeS/SAM binding site; other site
511145013462	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
511145013463	hypothetical protein; Provisional; Region: PRK10977
511145013464	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
511145013465	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
511145013466	intersubunit interface [polypeptide binding]; other site
511145013467	active site
511145013468	catalytic residue [active]
511145013469	thymidine phosphorylase; Reviewed; Region: deoA; PRK05820
511145013470	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
511145013471	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
511145013472	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; pfam07831
511145013473	phosphopentomutase; Provisional; Region: PRK05362
511145013474	purine nucleoside phosphorylase; Reviewed; Region: deoD; PRK05819
511145013475	putative DNA-binding transcriptional regulator; Provisional; Region: PRK09775
511145013476	HipA-like N-terminal domain; Region: HipA_N; pfam07805
511145013477	HipA-like C-terminal domain; Region: HipA_C; pfam07804
511145013478	lipoate-protein ligase A; Provisional; Region: lplA; PRK03822
511145013479	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
511145013480	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
511145013481	hypothetical protein; Provisional; Region: PRK11246
511145013482	phosphoserine phosphatase; Provisional; Region: serB; PRK11133
511145013483	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
511145013484	motif II; other site
511145013485	DNA repair protein RadA; Region: sms; TIGR00416
511145013486	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
511145013487	Walker A motif/ATP binding site; other site
511145013488	ATP binding site [chemical binding]; other site
511145013489	Walker B motif; other site
511145013490	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
511145013491	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
511145013492	non-specific DNA binding site [nucleotide binding]; other site
511145013493	salt bridge; other site
511145013494	bifunctional DNA-binding transcriptional repressor/ NMN adenylyltransferase; Provisional; Region: PRK08099
511145013495	sequence-specific DNA binding site [nucleotide binding]; other site
511145013496	Nicotinamide/nicotinate mononucleotide adenylyltransferase of bifunctional NadR-like proteins; Region: NMNAT_NadR; cd02167
511145013497	active site
511145013498	(T/H)XGH motif; other site
511145013499	Predicted ATPase/kinase involved in NAD metabolism [Coenzyme metabolism]; Region: NadR; COG3172
511145013500	putative ABC transporter ATP-binding protein; Reviewed; Region: PRK11819
511145013501	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145013502	The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature; Region: BAR; cl12013
511145013503	ABC transporter; Region: ABC_tran_2; pfam12848
511145013504	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
511145013505	lytic murein transglycosylase; Provisional; Region: PRK11619
511145013506	Soluble lytic murein transglycosylase L domain; Region: SLT_L; pfam14718
511145013507	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
511145013508	N-acetyl-D-glucosamine binding site [chemical binding]; other site
511145013509	catalytic residue [active]
511145013510	Trp operon repressor [Transcription]; Region: TrpR; COG2973
511145013511	inosine/xanthosine triphosphatase; Reviewed; Region: PRK05074
511145013512	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
511145013513	catalytic core [active]
511145013514	right oriC-binding transcriptional activator; Provisional; Region: PRK15121
511145013515	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145013516	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
511145013517	GyrI-like small molecule binding domain; Region: GyrI-like; pfam06445
511145013518	hypothetical protein; Provisional; Region: PRK10756
511145013519	DNA-binding response regulator CreB; Provisional; Region: PRK11083
511145013520	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145013521	active site
511145013522	phosphorylation site [posttranslational modification]
511145013523	intermolecular recognition site; other site
511145013524	dimerization interface [polypeptide binding]; other site
511145013525	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145013526	DNA binding site [nucleotide binding]
511145013527	sensory histidine kinase CreC; Provisional; Region: PRK11100
511145013528	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
511145013529	dimerization interface [polypeptide binding]; other site
511145013530	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
511145013531	dimer interface [polypeptide binding]; other site
511145013532	phosphorylation site [posttranslational modification]
511145013533	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
511145013534	ATP binding site [chemical binding]; other site
511145013535	Mg2+ binding site [ion binding]; other site
511145013536	G-X-G motif; other site
511145013537	Inner membrane protein involved in colicin E2 resistance [Defense mechanisms]; Region: CreD; COG4452
511145013538	two-component response regulator; Provisional; Region: PRK11173
511145013539	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
511145013540	active site
511145013541	phosphorylation site [posttranslational modification]
511145013542	intermolecular recognition site; other site
511145013543	dimerization interface [polypeptide binding]; other site
511145013544	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
511145013545	DNA binding site [nucleotide binding]
511145013546	putative RNA methyltransferase; Provisional; Region: PRK10433
511145013547	RNA methyltransferase, TrmH family, group 1; Region: rRNA_methyl_1; TIGR00050