-- dump date 20140618_223452 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 224308000001 SEQ_END SEQ_END NC_000964.3 4215606 4215606 DR NC_000964.3; contig end 4215606..4215606 Bacillus subtilis subsp. subtilis str. 168 <NULL_VALUE> NP_387882.1 CDS dnaA NC_000964.3 410 1750 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiator protein DnaA 410..1750 Bacillus subtilis subsp. subtilis str. 168 939978 NP_387883.1 CDS dnaN NC_000964.3 1939 3075 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1939..3075 Bacillus subtilis subsp. subtilis str. 168 939970 NP_387884.1 CDS yaaA NC_000964.3 3206 3421 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3206..3421 Bacillus subtilis subsp. subtilis str. 168 939444 NP_387885.1 CDS recF NC_000964.3 3437 4549 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; DNA replication and repair protein RecF 3437..4549 Bacillus subtilis subsp. subtilis str. 168 939454 NP_387886.2 CDS yaaB NC_000964.3 4567 4812 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4567..4812 Bacillus subtilis subsp. subtilis str. 168 939466 NP_387887.1 CDS gyrB NC_000964.3 4867 6783 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 4867..6783 Bacillus subtilis subsp. subtilis str. 168 939456 NP_387888.1 CDS gyrA NC_000964.3 6994 9459 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 6994..9459 Bacillus subtilis subsp. subtilis str. 168 940002 NP_387889.1 CDS yaaC NC_000964.3 14847 15794 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(14847..15794) Bacillus subtilis subsp. subtilis str. 168 939969 NP_387890.1 CDS guaB NC_000964.3 15915 17381 D catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine-5'-monophosphate dehydrogenase 15915..17381 Bacillus subtilis subsp. subtilis str. 168 938032 NP_387891.1 CDS dacA NC_000964.3 17534 18865 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8370539, 9864321; Product type e: enzyme; D-alanyl-D-alanine carboxypeptidase DacA 17534..18865 Bacillus subtilis subsp. subtilis str. 168 940000 NP_387892.1 CDS yaaD NC_000964.3 19062 19946 D with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 19062..19946 Bacillus subtilis subsp. subtilis str. 168 939988 NP_387893.1 CDS yaaE NC_000964.3 19968 20558 D with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 19968..20558 Bacillus subtilis subsp. subtilis str. 168 939971 NP_387894.1 CDS serS NC_000964.3 20880 22157 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; serine--tRNA ligase 20880..22157 Bacillus subtilis subsp. subtilis str. 168 939994 NP_387895.1 CDS dck NC_000964.3 22496 23149 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735, 6251049; Product type e: enzyme; deoxyadenosine/deoxycytidine kinase complement(22496..23149) Bacillus subtilis subsp. subtilis str. 168 936793 NP_387896.1 CDS dgk NC_000964.3 23146 23769 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735; Product type e: enzyme; deoxyguanosine kinase complement(23146..23769) Bacillus subtilis subsp. subtilis str. 168 937037 NP_387897.1 CDS yaaH NC_000964.3 23868 25151 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 11737650, 12177332, 10419957; Product type e: enzyme; spore germination protein YaaH complement(23868..25151) Bacillus subtilis subsp. subtilis str. 168 937029 NP_387898.1 CDS yaaI NC_000964.3 25221 25766 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2521622; Product type pe : enzyme; isochorismatase complement(25221..25766) Bacillus subtilis subsp. subtilis str. 168 937036 NP_387899.1 CDS tadA NC_000964.3 25852 26337 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16700551; Product type e: enzyme; tRNA-specific adenosine deaminase 25852..26337 Bacillus subtilis subsp. subtilis str. 168 937989 NP_387900.2 CDS dnaX NC_000964.3 26814 28505 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunit gamma/tau 26814..28505 Bacillus subtilis subsp. subtilis str. 168 936899 NP_387901.1 CDS yaaK NC_000964.3 28529 28852 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16740939; Product type f: factor; nucleoid-associated protein YaaK 28529..28852 Bacillus subtilis subsp. subtilis str. 168 937027 NP_387902.1 CDS recR NC_000964.3 28867 29463 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 28867..29463 Bacillus subtilis subsp. subtilis str. 168 937197 NP_387903.1 CDS yaaL NC_000964.3 29481 29705 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 29481..29705 Bacillus subtilis subsp. subtilis str. 168 937026 NP_387904.2 CDS bofA NC_000964.3 29772 30035 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15087499; Product type r: regulator; sigma-K factor-processing regulator BofA 29772..30035 Bacillus subtilis subsp. subtilis str. 168 937025 NP_387905.1 CDS csfB NC_000964.3 35531 35725 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 8759874; Product type cp: cell process; sporulation protein CsfB 35531..35725 Bacillus subtilis subsp. subtilis str. 168 937016 NP_387906.1 CDS xpaC NC_000964.3 35845 36459 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 5-bromo 4-chloroindolyl phosphate hydrolysis protein XpaC 35845..36459 Bacillus subtilis subsp. subtilis str. 168 937019 NP_387907.1 CDS yaaN NC_000964.3 36478 37638 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12533473; hypothetical protein 36478..37638 Bacillus subtilis subsp. subtilis str. 168 936551 NP_387908.1 CDS yaaO NC_000964.3 37720 39162 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9723923; Product type pe : enzyme; hypothetical protein 37720..39162 Bacillus subtilis subsp. subtilis str. 168 937013 NP_387909.2 CDS tmk NC_000964.3 39159 39797 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 39159..39797 Bacillus subtilis subsp. subtilis str. 168 937018 NP_387910.1 CDS yaaQ NC_000964.3 39871 40200 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913081; hypothetical protein 39871..40200 Bacillus subtilis subsp. subtilis str. 168 938610 NP_387911.1 CDS yaaR NC_000964.3 40213 40653 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 40213..40653 Bacillus subtilis subsp. subtilis str. 168 936756 NP_387912.1 CDS holB NC_000964.3 40665 41654 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 40665..41654 Bacillus subtilis subsp. subtilis str. 168 935949 NP_387913.1 CDS yaaT NC_000964.3 41657 42484 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12270811; stage 0 sporulation protein YaaT 41657..42484 Bacillus subtilis subsp. subtilis str. 168 937012 NP_387914.1 CDS yabA NC_000964.3 42499 42858 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; initiation-control protein YabA 42499..42858 Bacillus subtilis subsp. subtilis str. 168 937008 NP_387915.1 CDS yabB NC_000964.3 42917 43660 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 42917..43660 Bacillus subtilis subsp. subtilis str. 168 937011 NP_387916.1 CDS yazA NC_000964.3 43647 43946 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11483577; Product type pe : enzyme; hypothetical protein 43647..43946 Bacillus subtilis subsp. subtilis str. 168 937002 NP_387917.1 CDS yabC NC_000964.3 43921 44799 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; ribosomal RNA small subunit methyltransferase I 43921..44799 Bacillus subtilis subsp. subtilis str. 168 937010 NP_387918.1 CDS abrB NC_000964.3 44848 45138 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 16223496, 16702211, 10754235, 10809710, 11101881, 11101897; Product type r: regulator; transition state regulatory protein AbrB complement(44848..45138) Bacillus subtilis subsp. subtilis str. 168 937009 NP_387919.1 CDS metS NC_000964.3 45633 47627 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionine--tRNA ligase 45633..47627 Bacillus subtilis subsp. subtilis str. 168 936877 NP_387920.1 CDS yabD NC_000964.3 47706 48473 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10747959, 16014871; Product type e: enzyme; deoxyribonuclease YabD 47706..48473 Bacillus subtilis subsp. subtilis str. 168 936949 NP_387921.1 CDS yabE NC_000964.3 48629 49942 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001, 19047346; Product type pe: enzyme; hypothetical protein 48629..49942 Bacillus subtilis subsp. subtilis str. 168 936891 NP_387922.1 CDS rnmV NC_000964.3 50087 50647 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11233981, 11976317, 12794188, 16077031; Product type e: enzyme; ribonuclease M5 50087..50647 Bacillus subtilis subsp. subtilis str. 168 937001 NP_387923.1 CDS ksgA NC_000964.3 50640 51518 D catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; ribosomal RNA small subunit methyltransferase A 50640..51518 Bacillus subtilis subsp. subtilis str. 168 936358 NP_387924.1 CDS yabG NC_000964.3 51680 52552 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 11040425, 16751597, 19060142; Product type cp: cell process; sporulation-specific protease YabG 51680..52552 Bacillus subtilis subsp. subtilis str. 168 937005 NP_387925.1 CDS veg NC_000964.3 52763 53023 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12761295; protein Veg 52763..53023 Bacillus subtilis subsp. subtilis str. 168 936744 NP_387926.1 CDS sspF NC_000964.3 53183 53368 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11092849, 7959056, 8982008; Product type cp: cell process; small acid-soluble spore protein SspF 53183..53368 Bacillus subtilis subsp. subtilis str. 168 936996 NP_387927.1 CDS ipk NC_000964.3 53516 54385 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-c-methyl-d-erythritol kinase 53516..54385 Bacillus subtilis subsp. subtilis str. 168 936970 NP_387928.1 CDS purR NC_000964.3 54441 55298 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12837783, 12837784, 15629952, 16163456; Product type r: regulator; Pur operon repressor 54441..55298 Bacillus subtilis subsp. subtilis str. 168 937000 NP_387929.1 CDS yabJ NC_000964.3 55295 55672 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12515541, 14729707, 10557275, 10919400, 10368157; Product type pe: enzyme; enamine/imine deaminase 55295..55672 Bacillus subtilis subsp. subtilis str. 168 936988 NP_387930.1 CDS spoVG NC_000964.3 55866 56159 D stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; septation protein SpoVG 55866..56159 Bacillus subtilis subsp. subtilis str. 168 936959 NP_387931.1 CDS glmU NC_000964.3 56352 57722 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 56352..57722 Bacillus subtilis subsp. subtilis str. 168 936139 NP_387932.1 CDS prs NC_000964.3 57745 58698 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 57745..58698 Bacillus subtilis subsp. subtilis str. 168 936985 NP_387933.1 CDS ctc NC_000964.3 58783 59397 D the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; general stress protein CTC 58783..59397 Bacillus subtilis subsp. subtilis str. 168 936984 NP_387934.1 CDS pth NC_000964.3 59504 60070 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 59504..60070 Bacillus subtilis subsp. subtilis str. 168 936740 NP_387935.1 CDS yabK NC_000964.3 60130 60360 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 60130..60360 Bacillus subtilis subsp. subtilis str. 168 936978 NP_387936.1 CDS mfd NC_000964.3 60430 63963 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 16950921, 8594198, 9535092; Product type f: factor; transcription-repair-coupling factor 60430..63963 Bacillus subtilis subsp. subtilis str. 168 936653 NP_387937.1 CDS spoVT NC_000964.3 64099 64635 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15063493, 15939023, 16159768, 18996130, 8755877; Product type r: regulator; stage V sporulation protein T 64099..64635 Bacillus subtilis subsp. subtilis str. 168 936975 NP_387938.1 CDS yabM NC_000964.3 64817 66415 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 64817..66415 Bacillus subtilis subsp. subtilis str. 168 936539 NP_387939.1 CDS yabN NC_000964.3 66405 67874 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11178267; Product type pe : enzyme; hypothetical protein 66405..67874 Bacillus subtilis subsp. subtilis str. 168 936973 NP_387940.1 CDS yabO NC_000964.3 67877 68137 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10675343, 10675344; Product type pf: factor; hypothetical protein 67877..68137 Bacillus subtilis subsp. subtilis str. 168 936800 NP_387941.1 CDS yabP NC_000964.3 68216 68518 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15231775, 10869437; Product type f: factor; spore protein YabP 68216..68518 Bacillus subtilis subsp. subtilis str. 168 936966 NP_387942.1 CDS yabQ NC_000964.3 68515 69150 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15849754, 16850406, 10869437; Product type f: factor; spore protein YabQ 68515..69150 Bacillus subtilis subsp. subtilis str. 168 936971 NP_387943.1 CDS divIC NC_000964.3 69168 69545 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 11994149, 12682299, 16936019; Product type f: factor; cell division protein DivIC 69168..69545 Bacillus subtilis subsp. subtilis str. 168 936786 NP_387944.1 CDS yabR NC_000964.3 69626 70012 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066026, 16014871, 9862121; Product type pe: enzyme; hypothetical protein 69626..70012 Bacillus subtilis subsp. subtilis str. 168 936574 NP_387945.1 CDS spoIIE NC_000964.3 70538 73021 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10747015, 12180929, 15126482, 15866939, 15978076; Product type e: enzyme; stage II sporulation protein E 70538..73021 Bacillus subtilis subsp. subtilis str. 168 938480 NP_387946.1 CDS yabS NC_000964.3 73106 73843 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 73106..73843 Bacillus subtilis subsp. subtilis str. 168 936965 NP_387947.2 CDS yabT NC_000964.3 73809 74825 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase 73809..74825 Bacillus subtilis subsp. subtilis str. 168 936964 NP_387948.1 CDS tilS NC_000964.3 74929 76347 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14527414, 16039592, 17005971; Product type e: enzyme; tRNA(ile)-lysidine synthase 74929..76347 Bacillus subtilis subsp. subtilis str. 168 936922 NP_387949.1 CDS hprT NC_000964.3 76344 76886 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 3110131, 6408059; Product type e: enzyme; hypoxanthine-guanine phosphoribosyltransferase 76344..76886 Bacillus subtilis subsp. subtilis str. 168 936945 NP_387950.1 CDS ftsH NC_000964.3 76984 78897 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10851010, 10913836, 12533473, 9076729, 9084181, 9287010, 9352926; Product type e: enzyme; ATP-dependent zinc metalloprotease FtsH 76984..78897 Bacillus subtilis subsp. subtilis str. 168 938094 NP_387951.2 CDS coaX NC_000964.3 79092 79868 D type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; type III pantothenate kinase 79092..79868 Bacillus subtilis subsp. subtilis str. 168 936960 NP_387952.1 CDS hslO NC_000964.3 79880 80755 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; 33 kDa chaperonin 79880..80755 Bacillus subtilis subsp. subtilis str. 168 936762 NP_387953.1 CDS yacD NC_000964.3 80802 81695 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182, 15856219; Product type pf: factor; peptidyl-prolyl cis-trans isomerase 80802..81695 Bacillus subtilis subsp. subtilis str. 168 936955 NP_387954.1 CDS cysK NC_000964.3 81771 82697 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 16267287, 16513748; Product type e: enzyme; cysteine synthase 81771..82697 Bacillus subtilis subsp. subtilis str. 168 936636 NP_387955.1 CDS pabB NC_000964.3 82864 84276 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16605270, 17114263, 2123867, 9084182; Product type e: enzyme; para-aminobenzoate synthase component 1 82864..84276 Bacillus subtilis subsp. subtilis str. 168 936926 NP_387956.1 CDS pabA NC_000964.3 84290 84874 D amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis; para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II 84290..84874 Bacillus subtilis subsp. subtilis str. 168 936441 NP_387957.1 CDS pabC NC_000964.3 84874 85755 D catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; aminodeoxychorismate lyase 84874..85755 Bacillus subtilis subsp. subtilis str. 168 936944 NP_387958.1 CDS sul NC_000964.3 85737 86594 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11007651, 2123867; Product type e: enzyme; dihydropteroate synthase 85737..86594 Bacillus subtilis subsp. subtilis str. 168 936256 NP_387959.1 CDS folB NC_000964.3 86587 86949 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16188473, 17176045, 17388809; Product type e : enzyme; dihydroneopterin aldolase 86587..86949 Bacillus subtilis subsp. subtilis str. 168 937976 NP_387960.1 CDS folK NC_000964.3 86946 87449 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17029412; Product type e: enzyme; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 86946..87449 Bacillus subtilis subsp. subtilis str. 168 936940 NP_387961.1 CDS yazB NC_000964.3 87401 87610 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 87401..87610 Bacillus subtilis subsp. subtilis str. 168 936295 NP_387962.1 CDS dusB NC_000964.3 87634 88635 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710, 15698474; Product type e: enzyme; tRNA-dihydrouridine synthase 87634..88635 Bacillus subtilis subsp. subtilis str. 168 936924 NP_387963.1 CDS lysS NC_000964.3 88727 90226 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysine--tRNA ligase 88727..90226 Bacillus subtilis subsp. subtilis str. 168 936911 NP_387964.1 CDS ctsR NC_000964.3 101449 101913 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069659, 12618461, 16163393, 9852015; Product type r: regulator; transcriptional regulator CtsR 101449..101913 Bacillus subtilis subsp. subtilis str. 168 936883 NP_387965.1 CDS mcsA NC_000964.3 101927 102484 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16163393; Product type f: factor; hypothetical protein 101927..102484 Bacillus subtilis subsp. subtilis str. 168 936845 NP_387966.1 CDS mcsB NC_000964.3 102484 103575 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16163393, 17380125; Product type e: enzyme; ATP:guanido phosphotransferase YacI 102484..103575 Bacillus subtilis subsp. subtilis str. 168 936939 NP_387967.1 CDS clpC NC_000964.3 103572 106004 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354604, 15529410, 16525504; Product type f: factor; negative regulator of genetic competence ClpC/MecB 103572..106004 Bacillus subtilis subsp. subtilis str. 168 938481 NP_387968.1 CDS radA NC_000964.3 106096 107472 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 106096..107472 Bacillus subtilis subsp. subtilis str. 168 936872 NP_387969.1 CDS yacK NC_000964.3 107476 108558 D non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 107476..108558 Bacillus subtilis subsp. subtilis str. 168 936868 NP_387970.1 CDS yacL NC_000964.3 108674 109774 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; PIN and TRAM-domain containing protein YacL 108674..109774 Bacillus subtilis subsp. subtilis str. 168 936863 NP_387971.1 CDS ispD NC_000964.3 109789 110487 D 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-D-methyl-D-erythritol 4-phosphate cytidylyltransferase 109789..110487 Bacillus subtilis subsp. subtilis str. 168 936855 NP_387972.1 CDS ispF NC_000964.3 110480 110956 D catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-D-methyl-D-erythritol 2,4-cyclodiphosphate synthase 110480..110956 Bacillus subtilis subsp. subtilis str. 168 936634 NP_387973.1 CDS gltX NC_000964.3 111047 112498 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamate--tRNA ligase 111047..112498 Bacillus subtilis subsp. subtilis str. 168 936862 NP_387974.1 CDS cysE NC_000964.3 112800 113453 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751, 10737181, 7510287; Product type e: enzyme; serine acetyltransferase 112800..113453 Bacillus subtilis subsp. subtilis str. 168 936831 NP_387975.1 CDS cysS NC_000964.3 113450 114850 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteine--tRNA ligase 113450..114850 Bacillus subtilis subsp. subtilis str. 168 936859 NP_387976.1 CDS mrnC NC_000964.3 114854 115285 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871; Product type e: enzyme; mini-ribonuclease 3 114854..115285 Bacillus subtilis subsp. subtilis str. 168 936369 NP_387977.1 CDS rlmB NC_000964.3 115269 116018 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11698387, 16014871; Product type e: enzyme; tRNA/rRNA methyltransferase TrmH 115269..116018 Bacillus subtilis subsp. subtilis str. 168 936861 NP_387978.1 CDS yacP NC_000964.3 116025 116537 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114934; Product type pe : enzyme; hypothetical protein 116025..116537 Bacillus subtilis subsp. subtilis str. 168 936993 NP_387979.1 CDS sigH NC_000964.3 116600 117256 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase sigma-H factor 116600..117256 Bacillus subtilis subsp. subtilis str. 168 936150 NP_387980.1 CDS rpmG NC_000964.3 117349 117498 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 2 117349..117498 Bacillus subtilis subsp. subtilis str. 168 936842 NP_387981.1 CDS secE NC_000964.3 117532 117711 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 117532..117711 Bacillus subtilis subsp. subtilis str. 168 936856 NP_387982.1 CDS nusG NC_000964.3 117890 118423 D Modulates Rho-dependent transcription termination; transcription termination/antitermination protein NusG 117890..118423 Bacillus subtilis subsp. subtilis str. 168 936851 NP_387983.2 CDS rplK NC_000964.3 118591 119016 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 118591..119016 Bacillus subtilis subsp. subtilis str. 168 936838 NP_387984.2 CDS rplA NC_000964.3 119111 119809 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 119111..119809 Bacillus subtilis subsp. subtilis str. 168 936843 NP_387985.2 CDS rplJ NC_000964.3 120061 120561 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 120061..120561 Bacillus subtilis subsp. subtilis str. 168 936153 NP_387986.1 CDS rplL NC_000964.3 120607 120978 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 120607..120978 Bacillus subtilis subsp. subtilis str. 168 935952 NP_387987.1 CDS ybxB NC_000964.3 121068 121673 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17010380; Product type e: enzyme; hypothetical protein 121068..121673 Bacillus subtilis subsp. subtilis str. 168 938465 NP_387988.2 CDS rpoB NC_000964.3 121919 125500 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 121919..125500 Bacillus subtilis subsp. subtilis str. 168 936335 NP_387989.2 CDS rpoC NC_000964.3 125562 129161 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 125562..129161 Bacillus subtilis subsp. subtilis str. 168 935977 NP_387990.1 CDS ybxF NC_000964.3 129340 129588 D in Bacillus subtilis this non-essential protein associates with the ribosome; ribosome-associated protein L7Ae-like 129340..129588 Bacillus subtilis subsp. subtilis str. 168 936829 NP_387991.2 CDS rpsL NC_000964.3 129702 130118 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 129702..130118 Bacillus subtilis subsp. subtilis str. 168 936616 NP_387992.2 CDS rpsG NC_000964.3 130160 130630 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 130160..130630 Bacillus subtilis subsp. subtilis str. 168 935997 NP_387993.2 CDS fusA NC_000964.3 130684 132762 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 130684..132762 Bacillus subtilis subsp. subtilis str. 168 936826 NP_387994.1 CDS tufA NC_000964.3 132882 134072 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 132882..134072 Bacillus subtilis subsp. subtilis str. 168 935965 NP_387995.2 CDS ybaC NC_000964.3 134171 135127 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase YbaC 134171..135127 Bacillus subtilis subsp. subtilis str. 168 936866 NP_387996.1 CDS rpsJ NC_000964.3 135364 135672 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 135364..135672 Bacillus subtilis subsp. subtilis str. 168 936825 NP_387997.1 CDS rplC NC_000964.3 135712 136341 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 135712..136341 Bacillus subtilis subsp. subtilis str. 168 936239 NP_387998.1 CDS rplD NC_000964.3 136369 136992 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 136369..136992 Bacillus subtilis subsp. subtilis str. 168 936690 NP_387999.2 CDS rplW NC_000964.3 136992 137279 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 136992..137279 Bacillus subtilis subsp. subtilis str. 168 936820 NP_388000.2 CDS rplB NC_000964.3 137311 138144 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 137311..138144 Bacillus subtilis subsp. subtilis str. 168 936817 NP_388001.1 CDS rpsS NC_000964.3 138202 138480 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 138202..138480 Bacillus subtilis subsp. subtilis str. 168 936818 NP_388002.1 CDS rplV NC_000964.3 138497 138838 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 138497..138838 Bacillus subtilis subsp. subtilis str. 168 938123 NP_388003.2 CDS rpsC NC_000964.3 138842 139498 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 138842..139498 Bacillus subtilis subsp. subtilis str. 168 936808 NP_388004.1 CDS rplP NC_000964.3 139500 139934 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 139500..139934 Bacillus subtilis subsp. subtilis str. 168 936807 NP_388005.1 CDS rpmC NC_000964.3 139924 140124 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 139924..140124 Bacillus subtilis subsp. subtilis str. 168 936801 NP_388006.1 CDS rpsQ NC_000964.3 140147 140410 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 140147..140410 Bacillus subtilis subsp. subtilis str. 168 936805 NP_388007.1 CDS rplN NC_000964.3 140451 140819 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 140451..140819 Bacillus subtilis subsp. subtilis str. 168 935939 NP_388008.1 CDS rplX NC_000964.3 140857 141168 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 140857..141168 Bacillus subtilis subsp. subtilis str. 168 936799 NP_388009.1 CDS rplE NC_000964.3 141195 141734 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 141195..141734 Bacillus subtilis subsp. subtilis str. 168 936981 NP_388010.1 CDS rpsN NC_000964.3 141757 141942 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 141757..141942 Bacillus subtilis subsp. subtilis str. 168 935946 NP_388011.2 CDS rpsH NC_000964.3 141974 142372 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 141974..142372 Bacillus subtilis subsp. subtilis str. 168 936328 NP_388012.1 CDS rplF NC_000964.3 142402 142941 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 142402..142941 Bacillus subtilis subsp. subtilis str. 168 938229 NP_388013.2 CDS rplR NC_000964.3 142974 143336 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 142974..143336 Bacillus subtilis subsp. subtilis str. 168 936785 NP_388014.1 CDS rpsE NC_000964.3 143361 143861 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 143361..143861 Bacillus subtilis subsp. subtilis str. 168 938012 NP_388015.1 CDS rpmD NC_000964.3 143875 144054 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 143875..144054 Bacillus subtilis subsp. subtilis str. 168 936920 NP_388016.1 CDS rplO NC_000964.3 144085 144525 D late assembly protein; 50S ribosomal protein L15 144085..144525 Bacillus subtilis subsp. subtilis str. 168 935940 NP_388017.1 CDS secY NC_000964.3 144527 145822 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; protein translocase subunit SecY 144527..145822 Bacillus subtilis subsp. subtilis str. 168 936779 NP_388018.1 CDS adk NC_000964.3 145877 146530 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 145877..146530 Bacillus subtilis subsp. subtilis str. 168 938508 NP_388019.1 CDS mapA NC_000964.3 146527 147273 D catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1 146527..147273 Bacillus subtilis subsp. subtilis str. 168 938929 YP_003097669.1 CDS ybzG NC_000964.3 147312 147536 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17157877; Product type pf : factor; ribosome-binding protein YbzG 147312..147536 Bacillus subtilis subsp. subtilis str. 168 8303095 NP_388020.1 CDS infA NC_000964.3 147585 147803 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 147585..147803 Bacillus subtilis subsp. subtilis str. 168 938924 NP_388021.1 CDS rpmJ NC_000964.3 147837 147950 D smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 147837..147950 Bacillus subtilis subsp. subtilis str. 168 938927 NP_388022.2 CDS rpsM NC_000964.3 147973 148338 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 147973..148338 Bacillus subtilis subsp. subtilis str. 168 938928 NP_388023.1 CDS rpsK NC_000964.3 148359 148754 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 148359..148754 Bacillus subtilis subsp. subtilis str. 168 938926 NP_388024.1 CDS rpoA NC_000964.3 148931 149875 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 148931..149875 Bacillus subtilis subsp. subtilis str. 168 938921 NP_388025.1 CDS rplQ NC_000964.3 149953 150315 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 149953..150315 Bacillus subtilis subsp. subtilis str. 168 938918 NP_388026.2 CDS cbiO NC_000964.3 150443 151288 D with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene; energy-coupling factor transporter ATP-binding protein EcfA1 150443..151288 Bacillus subtilis subsp. subtilis str. 168 938925 NP_388027.1 CDS cbiO NC_000964.3 151303 152133 D with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene; energy-coupling factor transporter ATP-binding protein EcfA2 151303..152133 Bacillus subtilis subsp. subtilis str. 168 938922 NP_388028.2 CDS ybaF NC_000964.3 152130 152927 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; energy-coupling factor transporter transmembrane protein EcfT 152130..152927 Bacillus subtilis subsp. subtilis str. 168 938923 NP_388029.2 CDS truA NC_000964.3 152937 153680 D mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 152937..153680 Bacillus subtilis subsp. subtilis str. 168 938920 NP_388030.2 CDS rplM NC_000964.3 153842 154279 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 153842..154279 Bacillus subtilis subsp. subtilis str. 168 938915 NP_388031.1 CDS rpsI NC_000964.3 154300 154692 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 154300..154692 Bacillus subtilis subsp. subtilis str. 168 938912 NP_388032.2 CDS ybaJ NC_000964.3 155156 155923 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 155156..155923 Bacillus subtilis subsp. subtilis str. 168 938919 NP_388033.1 CDS ybaK NC_000964.3 156109 156552 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227, 16267290; Product type pe: enzyme; hypothetical protein 156109..156552 Bacillus subtilis subsp. subtilis str. 168 938916 NP_388034.1 CDS cwlD NC_000964.3 156612 157325 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 16267290; Product type e: enzyme; germination-specific N-acetylmuramoyl-L-alanine amidase 156612..157325 Bacillus subtilis subsp. subtilis str. 168 938917 NP_388035.1 CDS salA NC_000964.3 157421 158479 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11790741, 15126467; Product type r: regulator; protein mrp homolog SalA 157421..158479 Bacillus subtilis subsp. subtilis str. 168 938914 NP_388036.1 CDS gerD NC_000964.3 158515 159072 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17122337, 10618233, 10376819; Product type f: factor; spore germination protein GerD complement(158515..159072) Bacillus subtilis subsp. subtilis str. 168 938910 NP_388037.1 CDS kbaA NC_000964.3 159182 159778 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8576055; Product type r: regulator; kinB-signaling pathway activation protein 159182..159778 Bacillus subtilis subsp. subtilis str. 168 938913 NP_388038.1 CDS ybaN NC_000964.3 159779 160543 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 15547282; Product type ph: phenotype; polysaccharide deacetylase PdaB complement(159779..160543) Bacillus subtilis subsp. subtilis str. 168 938911 NP_388039.1 CDS ybaR NC_000964.3 177083 178519 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type m: membrane component; sulfate transporter YbaR 177083..178519 Bacillus subtilis subsp. subtilis str. 168 938890 NP_388040.2 CDS ybaS NC_000964.3 178665 179585 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 178665..179585 Bacillus subtilis subsp. subtilis str. 168 938892 NP_388041.2 CDS ybbA NC_000964.3 179595 180347 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 2974033; Product type pe: enzyme; hypothetical protein complement(179595..180347) Bacillus subtilis subsp. subtilis str. 168 938887 NP_388042.2 CDS feuC NC_000964.3 180344 181354 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter; iron-uptake system permease protein FeuC complement(180344..181354) Bacillus subtilis subsp. subtilis str. 168 938893 NP_388043.1 CDS feuB NC_000964.3 181347 182351 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter; iron-uptake system permease protein FeuB complement(181347..182351) Bacillus subtilis subsp. subtilis str. 168 938884 NP_388044.1 CDS feuA NC_000964.3 182370 183323 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8388528; Product type lp: lipoprotein; iron-uptake system-binding protein complement(182370..183323) Bacillus subtilis subsp. subtilis str. 168 938891 NP_388045.1 CDS ybbB NC_000964.3 183414 185003 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator complement(183414..185003) Bacillus subtilis subsp. subtilis str. 168 938888 NP_388046.1 CDS ybbC NC_000964.3 185194 186438 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(185194..186438) Bacillus subtilis subsp. subtilis str. 168 938889 NP_388047.1 CDS ybbD NC_000964.3 186452 188380 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8063094; Product type pe : enzyme; lipoprotein complement(186452..188380) Bacillus subtilis subsp. subtilis str. 168 938881 NP_388048.2 CDS ybbE NC_000964.3 188408 189733 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16452451; Product type pe : enzyme; hypothetical protein complement(188408..189733) Bacillus subtilis subsp. subtilis str. 168 938886 NP_388049.3 CDS ybbF NC_000964.3 189790 191157 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 10627040; Product type pt: transporter; PTS system EIIBC component YbbF complement(189790..191157) Bacillus subtilis subsp. subtilis str. 168 938879 NP_388050.1 CDS ybbH NC_000964.3 191183 192034 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; RpiR family transcriptional regulator complement(191183..192034) Bacillus subtilis subsp. subtilis str. 168 938885 NP_388051.1 CDS murQ NC_000964.3 192051 192965 R catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase complement(192051..192965) Bacillus subtilis subsp. subtilis str. 168 938882 NP_388052.2 CDS ybbJ NC_000964.3 193075 193557 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YbbJ complement(193075..193557) Bacillus subtilis subsp. subtilis str. 168 938883 NP_388053.2 CDS ybbK NC_000964.3 193570 194025 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(193570..194025) Bacillus subtilis subsp. subtilis str. 168 938877 NP_388054.1 CDS sigW NC_000964.3 194849 195412 D Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial; RNA polymerase sigma factor SigW 194849..195412 Bacillus subtilis subsp. subtilis str. 168 938868 NP_388055.1 CDS rsiW NC_000964.3 195426 196052 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127; Product type r: regulator; anti-sigma-W factor RsiW 195426..196052 Bacillus subtilis subsp. subtilis str. 168 938876 NP_388056.2 CDS ybbP NC_000964.3 196213 197034 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 196213..197034 Bacillus subtilis subsp. subtilis str. 168 938735 NP_388057.2 CDS ybbR NC_000964.3 197027 198478 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16236721; YbbR-like domain-containing protein YbbR 197027..198478 Bacillus subtilis subsp. subtilis str. 168 938867 NP_388058.1 CDS glmM NC_000964.3 198497 199843 D catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 198497..199843 Bacillus subtilis subsp. subtilis str. 168 938632 NP_388059.1 CDS glmS NC_000964.3 200277 202079 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glutamine--fructose-6-phosphate aminotransferase 200277..202079 Bacillus subtilis subsp. subtilis str. 168 938736 NP_388061.1 CDS alkA NC_000964.3 202547 203458 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7565865, 8376346; Product type e: enzyme; DNA-3-methyladenine glycosylase complement(202547..203458) Bacillus subtilis subsp. subtilis str. 168 938586 NP_388062.1 CDS adaA NC_000964.3 203729 204364 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme; bifunctional transcriptional activator/DNA repair enzyme AdaA 203729..204364 Bacillus subtilis subsp. subtilis str. 168 938648 NP_388063.1 CDS adaB NC_000964.3 204351 204890 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme; methylated-dna--protein-cysteine methyltransferase 204351..204890 Bacillus subtilis subsp. subtilis str. 168 938673 NP_388064.1 CDS ndhF NC_000964.3 205409 206926 D Catalyzes the transfer of electrons from NADH to ubiquinone; NADH-quinone oxidoreductase subunit 5 205409..206926 Bacillus subtilis subsp. subtilis str. 168 938593 NP_388065.2 CDS ybcC NC_000964.3 206941 209556 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 206941..209556 Bacillus subtilis subsp. subtilis str. 168 938603 NP_388067.1 CDS ybcF NC_000964.3 209633 210160 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carbonic anhydrase-like protein YbcF 209633..210160 Bacillus subtilis subsp. subtilis str. 168 938524 NP_388068.1 CDS ybcH NC_000964.3 210224 210514 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 210224..210514 Bacillus subtilis subsp. subtilis str. 168 938573 NP_388069.1 CDS ybcI NC_000964.3 210572 210946 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 210572..210946 Bacillus subtilis subsp. subtilis str. 168 938568 YP_003097670.1 CDS ybzH NC_000964.3 211429 211731 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 211429..211731 Bacillus subtilis subsp. subtilis str. 168 8302965 NP_388070.1 CDS ybcL NC_000964.3 211859 213031 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15812018, 15849754, 16850406; Product type pt: transporter; MFS transporter 211859..213031 Bacillus subtilis subsp. subtilis str. 168 938536 NP_388071.1 CDS ybcM NC_000964.3 213155 213469 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 213155..213469 Bacillus subtilis subsp. subtilis str. 168 938504 NP_388072.1 CDS skfA NC_000964.3 213941 214108 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type f: factor; sporulation-killing factor SkfA 213941..214108 Bacillus subtilis subsp. subtilis str. 168 938506 NP_388073.2 CDS skfB NC_000964.3 214175 215407 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 18307109; Product type f: factor; hypothetical protein 214175..215407 Bacillus subtilis subsp. subtilis str. 168 938501 YP_003097671.1 CDS skfC NC_000964.3 215404 216894 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter; sporulation-killing factor biosynthesis protein SkfC 215404..216894 Bacillus subtilis subsp. subtilis str. 168 8302931 NP_388077.1 CDS skfE NC_000964.3 216913 217632 D Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; SkfA peptide export ATP-binding protein SkfE 216913..217632 Bacillus subtilis subsp. subtilis str. 168 938498 NP_388078.2 CDS skfF NC_000964.3 217697 219040 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter; bacteriocin-SkfA transport system permease SkfF 217697..219040 Bacillus subtilis subsp. subtilis str. 168 938494 NP_388079.2 CDS skfG NC_000964.3 219087 219602 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype; hypothetical protein 219087..219602 Bacillus subtilis subsp. subtilis str. 168 938502 NP_388080.2 CDS skfH NC_000964.3 219607 220032 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype; thioredoxin 219607..220032 Bacillus subtilis subsp. subtilis str. 168 938499 NP_388081.2 CDS ybdG NC_000964.3 220279 221256 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 220279..221256 Bacillus subtilis subsp. subtilis str. 168 938500 NP_388082.1 CDS ybdJ NC_000964.3 221258 221929 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 221258..221929 Bacillus subtilis subsp. subtilis str. 168 938485 NP_388083.1 CDS ybdK NC_000964.3 221950 222912 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 221950..222912 Bacillus subtilis subsp. subtilis str. 168 938496 YP_003097672.1 CDS ybzI NC_000964.3 222971 223234 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 222971..223234 Bacillus subtilis subsp. subtilis str. 168 8303143 NP_388085.1 CDS ybdM NC_000964.3 223219 223989 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase complement(223219..223989) Bacillus subtilis subsp. subtilis str. 168 938464 NP_388086.1 CDS ybdN NC_000964.3 224075 224932 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16794953; Product type h : extrachromosomal origin; hypothetical protein complement(224075..224932) Bacillus subtilis subsp. subtilis str. 168 938489 NP_388087.1 CDS ybdO NC_000964.3 225064 226248 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type h : extrachromosomal origin; hypothetical protein 225064..226248 Bacillus subtilis subsp. subtilis str. 168 938493 NP_388088.1 CDS ybxG NC_000964.3 226566 227954 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 226566..227954 Bacillus subtilis subsp. subtilis str. 168 938470 NP_388089.1 CDS csgA NC_000964.3 228066 228314 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9016963; Product type cp: cell process; sigma-G-dependent sporulation-specific SASP protein 228066..228314 Bacillus subtilis subsp. subtilis str. 168 938448 NP_388090.1 CDS ybxH NC_000964.3 228331 228522 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 228331..228522 Bacillus subtilis subsp. subtilis str. 168 938445 NP_388091.1 CDS ybxI NC_000964.3 228549 229352 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14742199; Product type e: enzyme; beta-lactamase YbxI complement(228549..229352) Bacillus subtilis subsp. subtilis str. 168 938466 NP_388092.1 CDS cypC NC_000964.3 229525 230778 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10529095; Product type e: enzyme; fatty-acid peroxygenase 229525..230778 Bacillus subtilis subsp. subtilis str. 168 938449 NP_388093.1 CDS ybyB NC_000964.3 230819 231079 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(230819..231079) Bacillus subtilis subsp. subtilis str. 168 938450 NP_388094.2 CDS ybeC NC_000964.3 231348 232967 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid-proton symporter YbeC 231348..232967 Bacillus subtilis subsp. subtilis str. 168 938442 NP_388095.1 CDS glpQ NC_000964.3 233014 233895 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081; Product type e: enzyme; glycerophosphoryl diester phosphodiesterase complement(233014..233895) Bacillus subtilis subsp. subtilis str. 168 938446 NP_388096.1 CDS glpT NC_000964.3 233994 235328 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406, 8012593; Product type t: transporter; glycerol-3-phosphate transporter complement(233994..235328) Bacillus subtilis subsp. subtilis str. 168 938447 NP_388097.1 CDS ybeF NC_000964.3 235625 235873 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 235625..235873 Bacillus subtilis subsp. subtilis str. 168 938444 NP_388098.1 CDS ybfA NC_000964.3 235965 236882 D Evidence 4: Homologs of previously reported genes of unknown function; MarR family transcriptional regulator 235965..236882 Bacillus subtilis subsp. subtilis str. 168 938439 NP_388099.1 CDS ybfB NC_000964.3 236879 238129 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 236879..238129 Bacillus subtilis subsp. subtilis str. 168 938436 NP_388100.2 CDS ybfE NC_000964.3 238164 238448 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(238164..238448) Bacillus subtilis subsp. subtilis str. 168 938443 NP_388101.1 CDS ybfF NC_000964.3 238644 239555 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(238644..239555) Bacillus subtilis subsp. subtilis str. 168 938441 NP_388102.1 CDS ybfG NC_000964.3 239644 241842 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(239644..241842) Bacillus subtilis subsp. subtilis str. 168 938433 NP_388103.1 CDS ybfH NC_000964.3 241917 242837 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(241917..242837) Bacillus subtilis subsp. subtilis str. 168 938440 NP_388104.1 CDS ybfI NC_000964.3 242834 243661 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator complement(242834..243661) Bacillus subtilis subsp. subtilis str. 168 938437 NP_388105.1 CDS purT NC_000964.3 243892 245046 D non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 243892..245046 Bacillus subtilis subsp. subtilis str. 168 938438 NP_388106.1 CDS mpr NC_000964.3 245190 246131 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15375126; Product type e: enzyme; extracellular metalloprotease 245190..246131 Bacillus subtilis subsp. subtilis str. 168 938430 NP_388107.1 CDS ybfJ NC_000964.3 246094 246492 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 246094..246492 Bacillus subtilis subsp. subtilis str. 168 938435 NP_388108.1 CDS ybfK NC_000964.3 246658 247548 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11389736; Product type e: enzyme; carboxylesterase YbfK 246658..247548 Bacillus subtilis subsp. subtilis str. 168 938434 NP_388109.1 CDS pssA NC_000964.3 247744 248277 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14762009, 15743965, 15849754, 16850406; Product type e: enzyme; CDP-diacylglycerol--serine O-phosphatidyltransferase 247744..248277 Bacillus subtilis subsp. subtilis str. 168 938427 NP_388110.1 CDS ybfM NC_000964.3 248268 248756 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 14762009, 15849754, 16850406; Product type pe: enzyme; membrane protein 248268..248756 Bacillus subtilis subsp. subtilis str. 168 938432 NP_388111.1 CDS psd NC_000964.3 248749 249540 D catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase proenzyme 248749..249540 Bacillus subtilis subsp. subtilis str. 168 938431 NP_388112.1 CDS ybfN NC_000964.3 249595 249873 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 249595..249873 Bacillus subtilis subsp. subtilis str. 168 938429 NP_388113.1 CDS ybfO NC_000964.3 249979 251319 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YbfO 249979..251319 Bacillus subtilis subsp. subtilis str. 168 938424 NP_388114.1 CDS ybfP NC_000964.3 251427 252314 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 251427..252314 Bacillus subtilis subsp. subtilis str. 168 938428 NP_388115.1 CDS ybfQ NC_000964.3 252514 253482 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme; hypothetical protein 252514..253482 Bacillus subtilis subsp. subtilis str. 168 938426 NP_388116.1 CDS gltP NC_000964.3 253518 254762 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7751298; Product type t: transporter; proton glutamate symport protein complement(253518..254762) Bacillus subtilis subsp. subtilis str. 168 938421 NP_388117.1 CDS nagP NC_000964.3 254907 256802 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10627040, 15849754, 16850406; Product type t : transporter; PTS system glucosamine-specific EIICBA component complement(254907..256802) Bacillus subtilis subsp. subtilis str. 168 938418 NP_388118.1 CDS nagBB NC_000964.3 256823 257572 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; glucosamine-6-phosphate deaminase 2 complement(256823..257572) Bacillus subtilis subsp. subtilis str. 168 938425 NP_388119.1 CDS ybgA NC_000964.3 257791 258498 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 257791..258498 Bacillus subtilis subsp. subtilis str. 168 938422 NP_388120.1 CDS ybgB NC_000964.3 258532 258807 D Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008; membrane protein 258532..258807 Bacillus subtilis subsp. subtilis str. 168 938423 NP_388121.1 CDS ybgE NC_000964.3 259016 260086 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain-amino acid transaminase 1 259016..260086 Bacillus subtilis subsp. subtilis str. 168 938420 NP_388122.1 CDS ybgF NC_000964.3 260123 261535 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 7704263; Product type pt: transporter; amino acid permease YbgF complement(260123..261535) Bacillus subtilis subsp. subtilis str. 168 938415 NP_388123.1 CDS mmuM NC_000964.3 261656 262603 R converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine S-methyltransferase YbgG complement(261656..262603) Bacillus subtilis subsp. subtilis str. 168 938412 NP_388124.2 CDS glnT NC_000964.3 262732 264168 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 15995196, 16850406; Product type t: transporter; sodium/glutamine symporter GlnT complement(262732..264168) Bacillus subtilis subsp. subtilis str. 168 938419 NP_388125.1 CDS ybgJ NC_000964.3 264191 265174 R catalyzes the formation of glutamate from glutamine; glutaminase 1 complement(264191..265174) Bacillus subtilis subsp. subtilis str. 168 938416 NP_388126.2 CDS glnJ NC_000964.3 265476 266708 D Evidence 2b: Function of strongly homologous gene; PubMedId: 11717295, 15995196; Product type rc : receptor; sensor histidine kinase 265476..266708 Bacillus subtilis subsp. subtilis str. 168 938417 NP_388127.1 CDS glnL NC_000964.3 266719 267663 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15995196; Product type r: regulator; transcriptional regulatory protein GlnL 266719..267663 Bacillus subtilis subsp. subtilis str. 168 938414 NP_388128.2 CDS ycbC NC_000964.3 267890 268816 D catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 267890..268816 Bacillus subtilis subsp. subtilis str. 168 938409 NP_388129.1 CDS ycbD NC_000964.3 268846 270312 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12044674, 17202142; Product type e: enzyme; aldehyde dehydrogenase YcbD 268846..270312 Bacillus subtilis subsp. subtilis str. 168 938406 NP_388130.2 CDS gudP NC_000964.3 270396 271763 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674, 15849754, 16850406; Product type t: transporter; glucarate transporter 270396..271763 Bacillus subtilis subsp. subtilis str. 168 938413 NP_388131.2 CDS gudD NC_000964.3 271800 273167 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type e: enzyme; glucarate dehydratase 271800..273167 Bacillus subtilis subsp. subtilis str. 168 938410 NP_388132.2 CDS ycbG NC_000964.3 273237 273938 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type r: regulator; GntR family transcriptional regulator 273237..273938 Bacillus subtilis subsp. subtilis str. 168 938411 NP_388133.2 CDS garD NC_000964.3 274029 275561 D Evidence 2b: Function of strongly homologous gene; PubMedId: 9772162; Product type e: enzyme; D-galactarate dehydratase 274029..275561 Bacillus subtilis subsp. subtilis str. 168 938407 NP_388134.1 CDS ycbJ NC_000964.3 275838 276758 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12044674; Product type pe : enzyme; hypothetical protein 275838..276758 Bacillus subtilis subsp. subtilis str. 168 938408 NP_388135.1 CDS rtpA NC_000964.3 277160 277321 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10706627, 11557884, 12855807, 15099736, 15213402, 15743934, 16306262; Product type r: regulator; tryptophan RNA-binding attenuator protein inhibitory protein 277160..277321 Bacillus subtilis subsp. subtilis str. 168 938403 NP_388136.1 CDS ycbK NC_000964.3 277342 278280 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10706627, 15063849, 15849754, 16850406, 16879415, 17114263; Product type pt : transporter; transporter 277342..278280 Bacillus subtilis subsp. subtilis str. 168 938405 NP_388137.2 CDS ycbL NC_000964.3 278377 279057 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 278377..279057 Bacillus subtilis subsp. subtilis str. 168 938400 NP_388138.2 CDS ycbM NC_000964.3 279059 279994 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 279059..279994 Bacillus subtilis subsp. subtilis str. 168 938397 NP_388139.2 CDS ycbN NC_000964.3 280086 281009 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040; Product type pt : transporter; ABC transporter ATP-binding protein 280086..281009 Bacillus subtilis subsp. subtilis str. 168 938404 NP_388140.3 CDS ycbO NC_000964.3 281028 281714 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 281028..281714 Bacillus subtilis subsp. subtilis str. 168 938401 NP_388141.1 CDS ycbP NC_000964.3 281769 282155 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(281769..282155) Bacillus subtilis subsp. subtilis str. 168 938402 NP_388142.2 CDS cwlJ NC_000964.3 282469 282897 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11466292, 11807087, 12177332, 16936016, 9515903; Product type e: enzyme; cell wall hydrolase CwlJ 282469..282897 Bacillus subtilis subsp. subtilis str. 168 938399 NP_388143.2 CDS ycbR NC_000964.3 283003 283734 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 283003..283734 Bacillus subtilis subsp. subtilis str. 168 938394 YP_003097673.1 CDS yczK NC_000964.3 283816 283992 D Evidence 6: Doubtful CDS; hypothetical protein 283816..283992 Bacillus subtilis subsp. subtilis str. 168 8302909 NP_388144.2 CDS phoD NC_000964.3 284011 285762 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719524, 12867413, 16698798; Product type e: enzyme; alkaline phosphatase D 284011..285762 Bacillus subtilis subsp. subtilis str. 168 938391 NP_388145.2 CDS tatAD NC_000964.3 285775 285987 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12867413, 15554971, 16678787, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatAd 285775..285987 Bacillus subtilis subsp. subtilis str. 168 938398 NP_388146.2 CDS tatCD NC_000964.3 286048 286776 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16698798, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatCd 286048..286776 Bacillus subtilis subsp. subtilis str. 168 938395 NP_388147.1 CDS pcp NC_000964.3 286773 287420 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(286773..287420) Bacillus subtilis subsp. subtilis str. 168 938396 NP_388148.2 CDS ycbU NC_000964.3 287499 288611 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminotransferase YcbU 287499..288611 Bacillus subtilis subsp. subtilis str. 168 938393 NP_388149.1 CDS lmrB NC_000964.3 288653 290092 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15317768, 15849754, 16850406; Product type t: transporter; lincomycin resistance protein LmrB complement(288653..290092) Bacillus subtilis subsp. subtilis str. 168 938388 NP_388150.1 CDS lmrA NC_000964.3 290132 290698 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12718394, 15317768, 17483215; Product type r: regulator; TetR family transcriptional regulator complement(290132..290698) Bacillus subtilis subsp. subtilis str. 168 938385 NP_388151.1 CDS ansZ NC_000964.3 290915 292042 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 17686772; Product type e: enzyme; asparaginase 290915..292042 Bacillus subtilis subsp. subtilis str. 168 938392 NP_388152.1 CDS estA NC_000964.3 292205 292843 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 18053819, 11029590, 8396026; Product type e: enzyme; lipase EstA 292205..292843 Bacillus subtilis subsp. subtilis str. 168 938389 NP_388153.1 CDS yczC NC_000964.3 292881 293264 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(292881..293264) Bacillus subtilis subsp. subtilis str. 168 938390 NP_388154.1 CDS yccF NC_000964.3 293499 294575 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 293499..294575 Bacillus subtilis subsp. subtilis str. 168 938387 NP_388155.1 CDS natK NC_000964.3 294615 295571 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type rc: receptor; sensor histidine kinase complement(294615..295571) Bacillus subtilis subsp. subtilis str. 168 938382 NP_388156.1 CDS natR NC_000964.3 295584 296285 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type r: regulator; transcriptional regulator complement(295584..296285) Bacillus subtilis subsp. subtilis str. 168 938379 NP_388157.1 CDS natA NC_000964.3 296429 297169 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 17322186; Product type t: transporter; ATP-binding transport protein NatA 296429..297169 Bacillus subtilis subsp. subtilis str. 168 938386 NP_388158.1 CDS natB NC_000964.3 297170 298330 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 17322186; Product type t: transporter; sodium efflux ABC transporter permease NatB 297170..298330 Bacillus subtilis subsp. subtilis str. 168 938383 NP_388159.1 CDS yccK NC_000964.3 298466 299398 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17322186; Product type pe : enzyme; oxidoreductase 298466..299398 Bacillus subtilis subsp. subtilis str. 168 938384 NP_388160.1 CDS ycdA NC_000964.3 299438 300502 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein complement(299438..300502) Bacillus subtilis subsp. subtilis str. 168 938380 NP_388161.1 CDS ycdB NC_000964.3 300830 302248 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 300830..302248 Bacillus subtilis subsp. subtilis str. 168 938381 NP_388162.1 CDS ycdC NC_000964.3 302435 303796 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 302435..303796 Bacillus subtilis subsp. subtilis str. 168 938376 NP_388163.1 CDS cwlK NC_000964.3 303804 304307 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17588176; Product type e: enzyme; peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK complement(303804..304307) Bacillus subtilis subsp. subtilis str. 168 938378 NP_388164.1 CDS rapJ NC_000964.3 304430 305551 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme; response regulator aspartate phosphatase J 304430..305551 Bacillus subtilis subsp. subtilis str. 168 938373 NP_388165.1 CDS ycdF NC_000964.3 305658 306434 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme; glucose 1-dehydrogenase 2 305658..306434 Bacillus subtilis subsp. subtilis str. 168 938377 NP_388166.1 CDS ycdG NC_000964.3 306459 308144 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544224; Product type pe : enzyme; oligo-1,6-glucosidase 2 306459..308144 Bacillus subtilis subsp. subtilis str. 168 938375 NP_388167.1 CDS adcA NC_000964.3 308332 309291 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12426338, 14730579, 9379902; Product type lp : lipoprotein; zinc transport system zinc-binding lipoprotein AdcA 308332..309291 Bacillus subtilis subsp. subtilis str. 168 938370 NP_388168.1 CDS adcC NC_000964.3 309347 310042 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9379902, 9811636; Product type t : transporter; zinc transport system ATP-binding protein AdcC 309347..310042 Bacillus subtilis subsp. subtilis str. 168 938374 NP_388169.1 CDS adcB NC_000964.3 310000 310842 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 9379902, 9811636; Product type t: transporter; zinc transport system permease protein AdcB 310000..310842 Bacillus subtilis subsp. subtilis str. 168 938367 NP_388170.2 CDS yceB NC_000964.3 310880 311875 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16428414; Product type pe : enzyme; hypothetical protein complement(310880..311875) Bacillus subtilis subsp. subtilis str. 168 938371 NP_388171.1 CDS yceC NC_000964.3 312159 312758 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; stress response protein SCP2 312159..312758 Bacillus subtilis subsp. subtilis str. 168 938372 NP_388172.1 CDS yceD NC_000964.3 312780 313361 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; general stress protein 16U 312780..313361 Bacillus subtilis subsp. subtilis str. 168 938364 NP_388173.1 CDS yceE NC_000964.3 313396 313974 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 313396..313974 Bacillus subtilis subsp. subtilis str. 168 938368 NP_388174.1 CDS yceF NC_000964.3 314025 314798 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 314025..314798 Bacillus subtilis subsp. subtilis str. 168 938369 NP_388175.1 CDS yceG NC_000964.3 314883 316496 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 314883..316496 Bacillus subtilis subsp. subtilis str. 168 938361 NP_388176.1 CDS yceH NC_000964.3 316512 317603 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 316512..317603 Bacillus subtilis subsp. subtilis str. 168 938366 NP_388177.1 CDS yceI NC_000964.3 317725 318927 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; niacin/nicotinamide transporter NaiP 317725..318927 Bacillus subtilis subsp. subtilis str. 168 938365 NP_388178.1 CDS yceJ NC_000964.3 319180 320352 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(319180..320352) Bacillus subtilis subsp. subtilis str. 168 938363 NP_388179.1 CDS yceK NC_000964.3 320421 320723 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator complement(320421..320723) Bacillus subtilis subsp. subtilis str. 168 938357 NP_388180.2 CDS opuAA NC_000964.3 321013 322269 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type t: transporter; glycine/betaine ABC transporter ATP-binding protein 321013..322269 Bacillus subtilis subsp. subtilis str. 168 938362 NP_388181.1 CDS opuAB NC_000964.3 322271 323119 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16225868, 16645306, 16850406, 8752321; Product type t : transporter; glycine betaine transport system permease protein OpuAB 322271..323119 Bacillus subtilis subsp. subtilis str. 168 938360 NP_388182.1 CDS opuAC NC_000964.3 323119 324000 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type lp: lipoprotein; glycine betaine-binding protein OpuAC 323119..324000 Bacillus subtilis subsp. subtilis str. 168 938354 NP_388183.2 CDS amhX NC_000964.3 324038 325189 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8768514; Product type e : enzyme; amidohydrolase AmhX complement(324038..325189) Bacillus subtilis subsp. subtilis str. 168 938351 NP_388184.2 CDS ycgA NC_000964.3 325339 326772 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 325339..326772 Bacillus subtilis subsp. subtilis str. 168 938359 NP_388185.2 CDS ycgB NC_000964.3 326888 327469 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 326888..327469 Bacillus subtilis subsp. subtilis str. 168 938355 NP_388186.2 CDS amyE NC_000964.3 327618 329597 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3117969, 9353930; Product type e: enzyme; alpha-amylase 327618..329597 Bacillus subtilis subsp. subtilis str. 168 938356 NP_388187.2 CDS ldh NC_000964.3 329774 330739 D Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 329774..330739 Bacillus subtilis subsp. subtilis str. 168 938348 NP_388188.2 CDS lctP NC_000964.3 330771 332396 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 15849754, 16428414, 16850406; Product type t: transporter; L-lactate permease 330771..332396 Bacillus subtilis subsp. subtilis str. 168 938353 NP_388189.2 CDS mdr NC_000964.3 332441 333979 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15489457, 15849754, 16850406, 9023234; Product type t: transporter; multidrug resistance protein complement(332441..333979) Bacillus subtilis subsp. subtilis str. 168 938345 NP_388190.2 CDS ycgE NC_000964.3 334092 334556 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 334092..334556 Bacillus subtilis subsp. subtilis str. 168 938352 NP_388191.1 CDS ycgF NC_000964.3 334630 335259 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid efflux protein YcgF 334630..335259 Bacillus subtilis subsp. subtilis str. 168 938349 NP_388192.2 CDS ycgG NC_000964.3 335329 336090 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 335329..336090 Bacillus subtilis subsp. subtilis str. 168 938350 NP_388193.2 CDS ycgH NC_000964.3 336092 337432 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(336092..337432) Bacillus subtilis subsp. subtilis str. 168 938347 NP_388194.3 CDS ycgI NC_000964.3 337562 338158 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16433904; Product type pe : enzyme; hypothetical protein 337562..338158 Bacillus subtilis subsp. subtilis str. 168 938342 NP_388195.1 CDS nadE NC_000964.3 338288 339106 D catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NH(3)-dependent NAD(+) synthetase 338288..339106 Bacillus subtilis subsp. subtilis str. 168 938339 NP_388196.2 CDS tmrB NC_000964.3 339156 339749 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15131133, 1624425, 7766032; Product type f: factor; tunicamycin resistance protein complement(339156..339749) Bacillus subtilis subsp. subtilis str. 168 938346 NP_388197.2 CDS aroK NC_000964.3 340025 340585 D catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 340025..340585 Bacillus subtilis subsp. subtilis str. 168 938343 NP_388198.2 CDS ycgJ NC_000964.3 340613 341374 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase complement(340613..341374) Bacillus subtilis subsp. subtilis str. 168 938344 NP_388199.2 CDS ycgK NC_000964.3 341492 342466 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pr : regulator; LysR family transcriptional regulator 341492..342466 Bacillus subtilis subsp. subtilis str. 168 938340 NP_388200.1 CDS cah NC_000964.3 342538 343494 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12842474; Product type e: enzyme; cephalosporin-C deacetylase 342538..343494 Bacillus subtilis subsp. subtilis str. 168 938341 NP_388201.1 CDS ycgL NC_000964.3 343578 344360 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 343578..344360 Bacillus subtilis subsp. subtilis str. 168 938336 NP_388202.1 CDS ycgM NC_000964.3 344551 345462 D Evidence 1b: Function experimentally demonstrated in the studied species; PubMedId: 17536821, 2118500; Product type e: enzyme; proline dehydrogenase 2 344551..345462 Bacillus subtilis subsp. subtilis str. 168 938338 NP_388203.2 CDS ycgN NC_000964.3 345479 347026 D catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase 2 345479..347026 Bacillus subtilis subsp. subtilis str. 168 938333 NP_388204.2 CDS ycgO NC_000964.3 347150 348571 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14976255, 15849754, 16850406; Product type pt: transporter; symporter 347150..348571 Bacillus subtilis subsp. subtilis str. 168 938330 NP_388205.2 CDS ycgP NC_000964.3 348724 349959 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 348724..349959 Bacillus subtilis subsp. subtilis str. 168 938337 NP_388206.1 CDS ycgQ NC_000964.3 349996 350853 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(349996..350853) Bacillus subtilis subsp. subtilis str. 168 938334 NP_388207.1 CDS ycgR NC_000964.3 350858 351742 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(350858..351742) Bacillus subtilis subsp. subtilis str. 168 938335 NP_388208.1 CDS ycgS NC_000964.3 351842 352696 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YcgS complement(351842..352696) Bacillus subtilis subsp. subtilis str. 168 938332 NP_388209.1 CDS ycgT NC_000964.3 352858 353868 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16672620; Product type pe : enzyme; ferredoxin--NADP reductase 1 352858..353868 Bacillus subtilis subsp. subtilis str. 168 938327 NP_388210.1 CDS nasF NC_000964.3 353900 355351 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme; uroporphyrinogen-iii C-methyltransferase complement(353900..355351) Bacillus subtilis subsp. subtilis str. 168 938324 NP_388211.1 CDS nasE NC_000964.3 355412 355732 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme; assimilatory nitrite reductase [NAD(P)H] small subunit complement(355412..355732) Bacillus subtilis subsp. subtilis str. 168 938331 NP_388212.1 CDS nasD NC_000964.3 355764 358181 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme; nitrite reductase complement(355764..358181) Bacillus subtilis subsp. subtilis str. 168 938329 NP_388213.2 CDS nasC NC_000964.3 358303 360435 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme; assimilatory nitrate reductase catalytic subunit complement(358303..360435) Bacillus subtilis subsp. subtilis str. 168 938321 NP_388214.2 CDS nasB NC_000964.3 360442 362757 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10940050, 10972836, 15028686, 7836289, 9765565; Product type e: enzyme; assimilatory nitrate reductase electron transfer subunit complement(360442..362757) Bacillus subtilis subsp. subtilis str. 168 938328 NP_388215.2 CDS nasA NC_000964.3 362937 364142 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7868621; Product type t: transporter; nitrate transporter 362937..364142 Bacillus subtilis subsp. subtilis str. 168 938326 NP_388216.2 CDS yciA NC_000964.3 364259 365173 D similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase folE2 364259..365173 Bacillus subtilis subsp. subtilis str. 168 938325 NP_388217.2 CDS yciB NC_000964.3 365170 365754 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338; Product type pt : transporter; L,D-transpeptidase YciB 365170..365754 Bacillus subtilis subsp. subtilis str. 168 938318 YP_003097674.1 CDS yczL NC_000964.3 365850 366035 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 365850..366035 Bacillus subtilis subsp. subtilis str. 168 8303053 NP_388218.1 CDS yciC NC_000964.3 366063 367256 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338, 18344368, 2013568, 9811636; Product type pt: transporter; metal chaperone YciC 366063..367256 Bacillus subtilis subsp. subtilis str. 168 938322 NP_388219.1 CDS yckA NC_000964.3 367305 367985 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid ABC transporter permease protein YckA complement(367305..367985) Bacillus subtilis subsp. subtilis str. 168 938323 NP_388220.1 CDS yckB NC_000964.3 367995 368858 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter extracellular-binding protein YckB complement(367995..368858) Bacillus subtilis subsp. subtilis str. 168 938320 NP_388221.1 CDS yckC NC_000964.3 369236 369691 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 369236..369691 Bacillus subtilis subsp. subtilis str. 168 938315 NP_388222.1 CDS yckD NC_000964.3 369773 370105 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 369773..370105 Bacillus subtilis subsp. subtilis str. 168 938319 NP_388223.1 CDS bglC NC_000964.3 370259 371692 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18069788; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglC 370259..371692 Bacillus subtilis subsp. subtilis str. 168 938317 NP_388224.1 CDS nin NC_000964.3 371729 372127 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663; Product type r: regulator; DNA-entry nuclease inhibitor complement(371729..372127) Bacillus subtilis subsp. subtilis str. 168 938312 NP_388225.2 CDS nucA NC_000964.3 372154 372597 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663, 2841296, 7746143; Product type e: enzyme; DNA-entry nuclease complement(372154..372597) Bacillus subtilis subsp. subtilis str. 168 938309 NP_388226.2 CDS tlpC NC_000964.3 372771 374492 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187186, 7704255, 7921238; Product type rc : receptor; methyl-accepting chemotaxis protein TlpC complement(372771..374492) Bacillus subtilis subsp. subtilis str. 168 938316 NP_388227.1 CDS hxlB NC_000964.3 374603 375160 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme; 3-hexulose-6-phosphate isomerase complement(374603..375160) Bacillus subtilis subsp. subtilis str. 168 938313 NP_388228.1 CDS hxlA NC_000964.3 375166 375798 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme; 3-hexulose-6-phosphate synthase complement(375166..375798) Bacillus subtilis subsp. subtilis str. 168 938314 NP_388229.2 CDS hxlR NC_000964.3 376032 376394 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15978081; Product type r: regulator; HxlR family transcriptional regulator 376032..376394 Bacillus subtilis subsp. subtilis str. 168 938311 NP_388230.2 CDS srfAA NC_000964.3 376968 387731 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 8288534, 8441623; Product type e: enzyme; surfactin synthase subunit 1 376968..387731 Bacillus subtilis subsp. subtilis str. 168 938306 NP_388231.2 CDS srfAB NC_000964.3 387744 398495 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase subunit 2 387744..398495 Bacillus subtilis subsp. subtilis str. 168 938303 NP_388232.1 CDS comS NC_000964.3 390880 391020 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10361283, 16554821, 8752331, 9696775; Product type r: regulator; competence protein S 390880..391020 Bacillus subtilis subsp. subtilis str. 168 938310 NP_388233.2 CDS srfAC NC_000964.3 398532 402359 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase subunit 3 398532..402359 Bacillus subtilis subsp. subtilis str. 168 938308 NP_388234.1 CDS srfAD NC_000964.3 402388 403116 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase thioesterase subunit 402388..403116 Bacillus subtilis subsp. subtilis str. 168 938300 NP_388235.2 CDS ycxA NC_000964.3 403217 404443 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 403217..404443 Bacillus subtilis subsp. subtilis str. 168 938307 NP_388236.1 CDS ycxB NC_000964.3 404458 405015 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(404458..405015) Bacillus subtilis subsp. subtilis str. 168 938305 NP_388237.2 CDS ycxC NC_000964.3 405069 406007 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(405069..406007) Bacillus subtilis subsp. subtilis str. 168 938297 NP_388238.1 CDS ycxD NC_000964.3 406131 407465 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 406131..407465 Bacillus subtilis subsp. subtilis str. 168 938304 NP_388240.2 CDS yczE NC_000964.3 408240 408887 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 17827323; Product type m : membrane component; membrane protein complement(408240..408887) Bacillus subtilis subsp. subtilis str. 168 938302 NP_388241.2 CDS tcyC NC_000964.3 409208 409951 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter; L-cystine import ATP-binding protein TcyC complement(409208..409951) Bacillus subtilis subsp. subtilis str. 168 938294 NP_388242.1 CDS tcyB NC_000964.3 409965 410669 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter; L-cystine transport system permease protein TcyB complement(409965..410669) Bacillus subtilis subsp. subtilis str. 168 938301 NP_388243.2 CDS tcyA NC_000964.3 410656 411462 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter; L-cystine-binding protein TcyA complement(410656..411462) Bacillus subtilis subsp. subtilis str. 168 938298 NP_388244.1 CDS yclA NC_000964.3 411578 412450 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator complement(411578..412450) Bacillus subtilis subsp. subtilis str. 168 938299 NP_388245.1 CDS yclB NC_000964.3 412540 413154 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10919793; Product type pe : enzyme; phenolic acid decarboxylase subunit B 412540..413154 Bacillus subtilis subsp. subtilis str. 168 938296 NP_388246.1 CDS ubiD NC_000964.3 413157 414578 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11029449, 18388975; Product type pe: enzyme; phenolic acid decarboxylase subunit C 413157..414578 Bacillus subtilis subsp. subtilis str. 168 938291 YP_003097675.1 CDS bsdD NC_000964.3 414595 414822 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15979273, 18388975; Product type e: enzyme; phenolic acid decarboxylase subunit D 414595..414822 Bacillus subtilis subsp. subtilis str. 168 8302940 NP_388247.2 CDS yclD NC_000964.3 414819 415283 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15979273; Product type pe : enzyme; hypothetical protein 414819..415283 Bacillus subtilis subsp. subtilis str. 168 938293 NP_388248.2 CDS yclE NC_000964.3 415350 416195 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YclE 415350..416195 Bacillus subtilis subsp. subtilis str. 168 938288 NP_388249.2 CDS dtpT NC_000964.3 416235 417713 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717292, 15849754, 16850406, 8458848; Product type t: transporter; transporter complement(416235..417713) Bacillus subtilis subsp. subtilis str. 168 938295 NP_388250.1 CDS yclG NC_000964.3 417993 419747 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 417993..419747 Bacillus subtilis subsp. subtilis str. 168 938292 NP_388251.1 CDS yczF NC_000964.3 419763 419984 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(419763..419984) Bacillus subtilis subsp. subtilis str. 168 938290 NP_388252.1 CDS gerKA NC_000964.3 420110 421744 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process; spore germination protein KA 420110..421744 Bacillus subtilis subsp. subtilis str. 168 938285 NP_388253.1 CDS gerKC NC_000964.3 421734 422957 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process; spore germination protein KC 421734..422957 Bacillus subtilis subsp. subtilis str. 168 938287 NP_388254.1 CDS gerKB NC_000964.3 422982 424103 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 15849754, 16707705, 16740944, 16850406; Product type cp: cell process; spore germination protein KB 422982..424103 Bacillus subtilis subsp. subtilis str. 168 938282 NP_388255.1 CDS yclH NC_000964.3 424208 424888 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein complement(424208..424888) Bacillus subtilis subsp. subtilis str. 168 938289 NP_388256.2 CDS yclI NC_000964.3 424904 426364 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter permease complement(424904..426364) Bacillus subtilis subsp. subtilis str. 168 938279 NP_388257.1 CDS yclJ NC_000964.3 426577 427260 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type r: regulator; transcriptional regulator 426577..427260 Bacillus subtilis subsp. subtilis str. 168 938286 NP_388258.1 CDS yclK NC_000964.3 427247 428668 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type rc: receptor; sensor histidine kinase 427247..428668 Bacillus subtilis subsp. subtilis str. 168 938283 NP_388259.1 CDS rapC NC_000964.3 428831 429979 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917; Product type e: enzyme; response regulator aspartate phosphatase C 428831..429979 Bacillus subtilis subsp. subtilis str. 168 938284 NP_388260.1 CDS phrC NC_000964.3 429963 430085 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917, 16816200; Product type r: regulator; phosphatase RapC inhibitor 429963..430085 Bacillus subtilis subsp. subtilis str. 168 938281 YP_003097677.1 CDS yczN NC_000964.3 430356 430469 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(430356..430469) Bacillus subtilis subsp. subtilis str. 168 8302990 NP_388261.1 CDS yclM NC_000964.3 430623 431987 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartokinase 3 complement(430623..431987) Bacillus subtilis subsp. subtilis str. 168 938276 NP_388262.1 CDS yclN NC_000964.3 432372 433322 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 432372..433322 Bacillus subtilis subsp. subtilis str. 168 938273 NP_388263.1 CDS yclO NC_000964.3 433315 434262 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 433315..434262 Bacillus subtilis subsp. subtilis str. 168 938280 NP_388264.1 CDS yclP NC_000964.3 434256 435014 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter ATP-binding protein 434256..435014 Bacillus subtilis subsp. subtilis str. 168 938278 NP_388265.1 CDS yclQ NC_000964.3 435036 435989 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter substrate-binding protein 435036..435989 Bacillus subtilis subsp. subtilis str. 168 938277 NP_388266.1 CDS ycnB NC_000964.3 436036 437454 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(436036..437454) Bacillus subtilis subsp. subtilis str. 168 938275 NP_388267.2 CDS ycnC NC_000964.3 437474 438352 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator complement(437474..438352) Bacillus subtilis subsp. subtilis str. 168 938270 NP_388268.1 CDS ycnD NC_000964.3 438516 439265 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16229462, 9836433; Product type e: enzyme; FMN reductase complement(438516..439265) Bacillus subtilis subsp. subtilis str. 168 938267 NP_388269.1 CDS ycnE NC_000964.3 439282 439569 R Evidence 4: Homologs of previously reported genes of unknown function; monooxygenase YcnE complement(439282..439569) Bacillus subtilis subsp. subtilis str. 168 938274 NP_388270.1 CDS yczG NC_000964.3 439709 440023 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 439709..440023 Bacillus subtilis subsp. subtilis str. 168 938272 NP_388271.1 CDS gabR NC_000964.3 440025 441464 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311; Product type r: regulator; GntR family transcriptional regulator complement(440025..441464) Bacillus subtilis subsp. subtilis str. 168 938271 NP_388272.1 CDS gabT NC_000964.3 441571 442881 D catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 441571..442881 Bacillus subtilis subsp. subtilis str. 168 938264 NP_388273.1 CDS gabD NC_000964.3 442950 444338 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 15590624, 9723923; Product type e : enzyme; succinate-semialdehyde dehydrogenase 442950..444338 Bacillus subtilis subsp. subtilis str. 168 939976 NP_388274.1 CDS glcU NC_000964.3 444461 445324 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438764, 15849754, 16850406; Product type t : transporter; glucose uptake protein GlcU 444461..445324 Bacillus subtilis subsp. subtilis str. 168 938268 NP_388275.1 CDS gdh NC_000964.3 445344 446129 D Converts glucose to D-glucono-1,5 lactone; glucose 1-dehydrogenase 445344..446129 Bacillus subtilis subsp. subtilis str. 168 938261 NP_388276.1 CDS ycnI NC_000964.3 446174 446788 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(446174..446788) Bacillus subtilis subsp. subtilis str. 168 938266 NP_388277.2 CDS ycnJ NC_000964.3 446801 448426 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter; copper transport protein YcnJ complement(446801..448426) Bacillus subtilis subsp. subtilis str. 168 938258 NP_388278.1 CDS ycnK NC_000964.3 448461 449033 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pr : regulator; DeoR family transcriptional regulator complement(448461..449033) Bacillus subtilis subsp. subtilis str. 168 938265 NP_388279.1 CDS ycnL NC_000964.3 449198 449551 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 18307109; Product type pe: enzyme; hypothetical protein 449198..449551 Bacillus subtilis subsp. subtilis str. 168 939465 NP_388280.2 CDS mtlA NC_000964.3 449724 451160 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter; PTS system mannitol-specific EIICB component 449724..451160 Bacillus subtilis subsp. subtilis str. 168 938263 YP_003097678.1 CDS mtlF NC_000964.3 451185 451616 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter; mannitol-specific phosphotransferase enzyme IIA component 451185..451616 Bacillus subtilis subsp. subtilis str. 168 8303136 NP_388281.2 CDS mtlD NC_000964.3 451618 452739 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme; mannitol-1-phosphate 5-dehydrogenase 451618..452739 Bacillus subtilis subsp. subtilis str. 168 939968 NP_388282.3 CDS ycsA NC_000964.3 452830 453894 D catalyzes the formation of oxaloglycolate from tartrate; also catalyzes the formation of pyruvate from malate and glycerate from tartrate; tartrate dehydrogenase/decarboxylase 452830..453894 Bacillus subtilis subsp. subtilis str. 168 938262 NP_388283.1 CDS sipU NC_000964.3 454029 454592 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14568161, 9325333; Product type e: enzyme; signal peptidase I U 454029..454592 Bacillus subtilis subsp. subtilis str. 168 939966 NP_388284.2 CDS yczH NC_000964.3 454652 455260 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase complement(454652..455260) Bacillus subtilis subsp. subtilis str. 168 938255 NP_388285.2 CDS ycsD NC_000964.3 455346 455738 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16291680; Product type pe: enzyme; hypothetical protein 455346..455738 Bacillus subtilis subsp. subtilis str. 168 938260 YP_003097679.1 CDS yczO NC_000964.3 455771 455935 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(455771..455935) Bacillus subtilis subsp. subtilis str. 168 8302943 NP_388286.2 CDS ycsE NC_000964.3 456068 456817 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 456068..456817 Bacillus subtilis subsp. subtilis str. 168 938252 NP_388287.3 CDS ycsF NC_000964.3 457023 457796 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme; hypothetical protein 457023..457796 Bacillus subtilis subsp. subtilis str. 168 938259 NP_388288.3 CDS ycsG NC_000964.3 457811 459025 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9334321; Product type pt: transporter; membrane protein 457811..459025 Bacillus subtilis subsp. subtilis str. 168 938257 NP_388289.3 CDS ycsI NC_000964.3 459049 459822 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; hypothetical protein 459049..459822 Bacillus subtilis subsp. subtilis str. 168 938647 NP_388290.2 CDS kipI NC_000964.3 459867 460589 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pf : factor; kinase A inhibitor 459867..460589 Bacillus subtilis subsp. subtilis str. 168 938256 YP_054571.2 CDS kipA NC_000964.3 460592 461599 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme; kipi antagonist 460592..461599 Bacillus subtilis subsp. subtilis str. 168 2914204 NP_388291.2 CDS kipR NC_000964.3 461615 462367 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9334321; Product type r: regulator; IclR family transcriptional regulator 461615..462367 Bacillus subtilis subsp. subtilis str. 168 939999 NP_388292.1 CDS lipC NC_000964.3 462431 463072 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17220230, 9334321; Product type e: enzyme; spore germination lipase LipC 462431..463072 Bacillus subtilis subsp. subtilis str. 168 938249 NP_388293.1 CDS yczI NC_000964.3 463245 463490 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 463245..463490 Bacillus subtilis subsp. subtilis str. 168 939989 NP_388294.1 CDS yczJ NC_000964.3 463496 463783 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(463496..463783) Bacillus subtilis subsp. subtilis str. 168 938254 NP_388295.1 CDS pbpC NC_000964.3 463934 465940 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8830698; Product type lp: lipoprotein; penicillin-binding protein 3 463934..465940 Bacillus subtilis subsp. subtilis str. 168 940139 NP_388296.1 CDS ycsN NC_000964.3 466042 466944 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 466042..466944 Bacillus subtilis subsp. subtilis str. 168 936168 NP_388297.1 CDS mtlR NC_000964.3 467130 469214 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type r: regulator; transcriptional regulator MtlR 467130..469214 Bacillus subtilis subsp. subtilis str. 168 938253 NP_388298.2 CDS ydaB NC_000964.3 469426 470937 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl--CoA ligase YdaB 469426..470937 Bacillus subtilis subsp. subtilis str. 168 938246 NP_388299.1 CDS ydaC NC_000964.3 470957 471502 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase complement(470957..471502) Bacillus subtilis subsp. subtilis str. 168 940142 NP_388300.1 CDS ydaD NC_000964.3 471709 472569 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme; general stress protein 39 471709..472569 Bacillus subtilis subsp. subtilis str. 168 938251 NP_388301.1 CDS ydaE NC_000964.3 472585 473088 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; D-lyxose ketol-isomerase 472585..473088 Bacillus subtilis subsp. subtilis str. 168 938182 NP_388302.1 CDS ydaF NC_000964.3 473174 473725 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15468321; Product type pe : enzyme; ribosomal N-acetyltransferase YdaF 473174..473725 Bacillus subtilis subsp. subtilis str. 168 938250 NP_388303.1 CDS ydaG NC_000964.3 473803 474225 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor; general stress protein 26 473803..474225 Bacillus subtilis subsp. subtilis str. 168 939958 NP_388304.1 CDS ydaH NC_000964.3 474731 475540 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 474731..475540 Bacillus subtilis subsp. subtilis str. 168 938243 NP_388305.1 CDS ydzA NC_000964.3 475584 475874 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(475584..475874) Bacillus subtilis subsp. subtilis str. 168 938248 NP_388306.1 CDS lrpC NC_000964.3 476059 476493 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10606655, 10913073, 12458218, 16407330, 16528101, 9341680; Product type r : regulator; AsnC family transcriptional regulator 476059..476493 Bacillus subtilis subsp. subtilis str. 168 940147 NP_388307.1 CDS topB NC_000964.3 476558 478741 D decatenates replicating daughter chromosomes; DNA topoisomerase 3 476558..478741 Bacillus subtilis subsp. subtilis str. 168 938247 NP_388308.1 CDS ydaJ NC_000964.3 478944 480032 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 478944..480032 Bacillus subtilis subsp. subtilis str. 168 938245 NP_388309.1 CDS ydaK NC_000964.3 480013 480864 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 480013..480864 Bacillus subtilis subsp. subtilis str. 168 938240 NP_388310.1 CDS ydaL NC_000964.3 480875 482584 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 480875..482584 Bacillus subtilis subsp. subtilis str. 168 938244 NP_388311.1 CDS ydaM NC_000964.3 482577 483839 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YdaM 482577..483839 Bacillus subtilis subsp. subtilis str. 168 939986 NP_388312.1 CDS ydaN NC_000964.3 483845 485956 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 483845..485956 Bacillus subtilis subsp. subtilis str. 168 940004 NP_388313.1 CDS ydaO NC_000964.3 486432 488255 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter; amino acid permease YdaO 486432..488255 Bacillus subtilis subsp. subtilis str. 168 938237 NP_388314.1 CDS mutT NC_000964.3 488314 488763 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513759; Product type pe : enzyme; 8-oxo-dGTP diphosphatase 488314..488763 Bacillus subtilis subsp. subtilis str. 168 938242 NP_388315.1 CDS ydaP NC_000964.3 488830 490554 D catalyzes the formation of acetyl phosphate from pyruvate; thiamine pyrophosphate-containing protein YdaP 488830..490554 Bacillus subtilis subsp. subtilis str. 168 938239 YP_003097680.1 CDS ydzK NC_000964.3 490777 491043 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein complement(490777..491043) Bacillus subtilis subsp. subtilis str. 168 8302999 NP_388317.1 CDS mntH NC_000964.3 491147 492424 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029030, 12950915, 14580210, 15849754, 16850406; Product type t : transporter; divalent metal cation transporter MntH complement(491147..492424) Bacillus subtilis subsp. subtilis str. 168 938241 NP_388318.1 CDS ydaS NC_000964.3 492654 492911 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(492654..492911) Bacillus subtilis subsp. subtilis str. 168 938230 NP_388319.1 CDS ydaT NC_000964.3 492989 493441 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(492989..493441) Bacillus subtilis subsp. subtilis str. 168 939950 NP_388320.1 CDS ydbA NC_000964.3 493559 494377 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 493559..494377 Bacillus subtilis subsp. subtilis str. 168 938238 NP_388321.1 CDS gsiB NC_000964.3 494506 494877 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651322, 9669336; Product type f: factor; glucose starvation-inducible protein B 494506..494877 Bacillus subtilis subsp. subtilis str. 168 938235 NP_388322.1 CDS ydbB NC_000964.3 495009 495350 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme; hypothetical protein 495009..495350 Bacillus subtilis subsp. subtilis str. 168 935969 NP_388323.1 CDS ydbC NC_000964.3 495344 495703 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 495344..495703 Bacillus subtilis subsp. subtilis str. 168 938234 NP_388324.1 CDS ydbD NC_000964.3 495740 496561 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15231799; Product type pe : enzyme; manganese catalase complement(495740..496561) Bacillus subtilis subsp. subtilis str. 168 938232 NP_388325.1 CDS dctB NC_000964.3 496646 497698 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10708364, 11566984, 1809844; Product type f : factor; C4-dicarboxylate-binding protein DctB complement(496646..497698) Bacillus subtilis subsp. subtilis str. 168 938226 NP_388326.1 CDS dctS NC_000964.3 497768 499375 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type rc: receptor; C4-dicarboxylate sensor kinase 497768..499375 Bacillus subtilis subsp. subtilis str. 168 938231 NP_388327.1 CDS dctR NC_000964.3 499365 500045 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type r: regulator; C4-dicarboxylate response regulator DctR 499365..500045 Bacillus subtilis subsp. subtilis str. 168 940148 NP_388328.1 CDS dctP NC_000964.3 500166 501431 D involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transport protein 500166..501431 Bacillus subtilis subsp. subtilis str. 168 938223 NP_388329.1 CDS ydbI NC_000964.3 501579 502631 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 501579..502631 Bacillus subtilis subsp. subtilis str. 168 939948 NP_388330.1 CDS ydbJ NC_000964.3 502908 503834 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 502908..503834 Bacillus subtilis subsp. subtilis str. 168 938228 NP_388331.1 CDS ydbK NC_000964.3 503854 504594 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 15849754, 16850406; Product type pt: transporter; membrane protein 503854..504594 Bacillus subtilis subsp. subtilis str. 168 939944 NP_388332.1 CDS ydbL NC_000964.3 504689 505024 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 504689..505024 Bacillus subtilis subsp. subtilis str. 168 938227 NP_388333.1 CDS ydbM NC_000964.3 505152 506297 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748; Product type pe: enzyme; acyl-CoA dehydrogenase YdbM 505152..506297 Bacillus subtilis subsp. subtilis str. 168 939949 NP_388334.1 CDS ydbN NC_000964.3 506322 506501 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229, 16428414; hypothetical protein complement(506322..506501) Bacillus subtilis subsp. subtilis str. 168 938190 NP_388335.1 CDS ydbO NC_000964.3 506866 507738 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter 506866..507738 Bacillus subtilis subsp. subtilis str. 168 938225 NP_388336.1 CDS ydbP NC_000964.3 507753 508073 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; thioredoxin complement(507753..508073) Bacillus subtilis subsp. subtilis str. 168 939940 NP_388337.1 CDS ddl NC_000964.3 508248 509312 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 508248..509312 Bacillus subtilis subsp. subtilis str. 168 938224 NP_388338.1 CDS murF NC_000964.3 509384 510757 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299; Product type e: enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 509384..510757 Bacillus subtilis subsp. subtilis str. 168 939947 NP_388339.1 CDS cshA NC_000964.3 511106 512641 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840; Product type e: enzyme; ATP-dependent RNA helicase 511106..512641 Bacillus subtilis subsp. subtilis str. 168 938170 NP_388340.1 CDS ydbS NC_000964.3 512814 513293 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 512814..513293 Bacillus subtilis subsp. subtilis str. 168 940149 NP_388341.1 CDS ydbT NC_000964.3 513283 514764 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 513283..514764 Bacillus subtilis subsp. subtilis str. 168 938221 NP_388342.1 CDS ydcA NC_000964.3 515016 515615 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15616571, 15849754, 16850406; rhomboid protease YdcA complement(515016..515615) Bacillus subtilis subsp. subtilis str. 168 939936 NP_388343.1 CDS acpS NC_000964.3 515710 516075 D Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; holo-[acyl-carrier-protein] synthase 515710..516075 Bacillus subtilis subsp. subtilis str. 168 938194 NP_388344.2 CDS ydcC NC_000964.3 516241 517257 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type lp : lipoprotein; sporulation protein YdcC 516241..517257 Bacillus subtilis subsp. subtilis str. 168 938166 NP_388345.1 CDS alrA NC_000964.3 517372 518541 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15043879, 18399999, 2835089; Product type e: enzyme; alanine racemase 1 517372..518541 Bacillus subtilis subsp. subtilis str. 168 939942 NP_388346.1 CDS endB NC_000964.3 518657 518938 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type r: regulator; antitoxin EndoAI 518657..518938 Bacillus subtilis subsp. subtilis str. 168 938177 NP_388347.1 CDS ndoA NC_000964.3 518943 519293 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type e: enzyme; mRNA interferase EndoA 518943..519293 Bacillus subtilis subsp. subtilis str. 168 939935 NP_388348.1 CDS rsbRA NC_000964.3 519408 520232 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT co-antagonist protein RsbRA 519408..520232 Bacillus subtilis subsp. subtilis str. 168 938176 NP_388349.1 CDS rsbS NC_000964.3 520237 520602 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT antagonist protein RsbS 520237..520602 Bacillus subtilis subsp. subtilis str. 168 938157 NP_388350.1 CDS rsbT NC_000964.3 520606 521007 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type e: enzyme; serine/threonine protein kinase 520606..521007 Bacillus subtilis subsp. subtilis str. 168 938168 NP_388351.1 CDS rsbU NC_000964.3 521019 522026 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665; Product type e: enzyme; phosphoserine phosphatase RsbU 521019..522026 Bacillus subtilis subsp. subtilis str. 168 939939 NP_388352.1 CDS rsbV NC_000964.3 522088 522417 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15342585, 15583165, 16077134, 16885458; Product type f: factor; anti-sigma-B factor antagonist 522088..522417 Bacillus subtilis subsp. subtilis str. 168 939930 NP_388353.1 CDS rsbW NC_000964.3 522414 522896 D binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; serine-protein kinase RsbW 522414..522896 Bacillus subtilis subsp. subtilis str. 168 938167 NP_388354.2 CDS sigB NC_000964.3 522862 523650 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; RNA polymerase sigma-B factor 522862..523650 Bacillus subtilis subsp. subtilis str. 168 939937 NP_388355.1 CDS rsbX NC_000964.3 523650 524249 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10671474, 12950928, 15466036, 9068644, 9658013; Product type e: enzyme; phosphoserine phosphatase RsbX 523650..524249 Bacillus subtilis subsp. subtilis str. 168 938155 NP_388356.1 CDS ydcF NC_000964.3 524492 524785 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 524492..524785 Bacillus subtilis subsp. subtilis str. 168 938158 NP_388357.1 CDS ydcG NC_000964.3 524782 525222 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 524782..525222 Bacillus subtilis subsp. subtilis str. 168 938162 NP_388358.1 CDS ydcH NC_000964.3 525206 525649 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12088660; Product type pr : regulator; MarR family transcriptional regulator 525206..525649 Bacillus subtilis subsp. subtilis str. 168 939928 NP_388359.2 CDS ydcI NC_000964.3 525743 527902 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 525743..527902 Bacillus subtilis subsp. subtilis str. 168 939932 NP_388360.1 CDS ydcK NC_000964.3 528129 528581 D Evidence 4: Homologs of previously reported genes of unknown function; protein SprT-like 528129..528581 Bacillus subtilis subsp. subtilis str. 168 938154 NP_388361.1 CDS ydcL NC_000964.3 529505 530611 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; ICEBs1 integrase complement(529505..530611) Bacillus subtilis subsp. subtilis str. 168 938151 NP_388362.1 CDS immA NC_000964.3 530624 531133 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18761623; Product type cp: cell process; metallopeptidase ImmA complement(530624..531133) Bacillus subtilis subsp. subtilis str. 168 939924 NP_388363.1 CDS immR NC_000964.3 531130 531513 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin; XRE family transcriptional regulator complement(531130..531513) Bacillus subtilis subsp. subtilis str. 168 938150 NP_388364.1 CDS sacV NC_000964.3 531787 531981 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3269394; Product type h : extrachromosomal origin; excisionase 531787..531981 Bacillus subtilis subsp. subtilis str. 168 939938 YP_003097681.1 CDS ydzL NC_000964.3 531978 532238 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 531978..532238 Bacillus subtilis subsp. subtilis str. 168 8303154 NP_388365.1 CDS ydcO NC_000964.3 532292 532552 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 532292..532552 Bacillus subtilis subsp. subtilis str. 168 938142 NP_388366.1 CDS ydcP NC_000964.3 532922 533302 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 532922..533302 Bacillus subtilis subsp. subtilis str. 168 939920 NP_388367.1 CDS ydcQ NC_000964.3 533338 534780 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; Ftsk domain-containing protein YdcQ 533338..534780 Bacillus subtilis subsp. subtilis str. 168 939923 NP_388368.1 CDS ydcR NC_000964.3 534773 535831 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA relaxase NicK 534773..535831 Bacillus subtilis subsp. subtilis str. 168 939922 NP_388369.1 CDS ydcS NC_000964.3 536096 536365 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536096..536365 Bacillus subtilis subsp. subtilis str. 168 938148 NP_388370.1 CDS ydcT NC_000964.3 536404 536670 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536404..536670 Bacillus subtilis subsp. subtilis str. 168 938146 NP_388371.1 CDS yddA NC_000964.3 536687 536995 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536687..536995 Bacillus subtilis subsp. subtilis str. 168 938135 NP_388372.1 CDS yddB NC_000964.3 536985 538049 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536985..538049 Bacillus subtilis subsp. subtilis str. 168 939918 NP_388373.1 CDS yddC NC_000964.3 538061 538309 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 538061..538309 Bacillus subtilis subsp. subtilis str. 168 938144 NP_388374.1 CDS yddD NC_000964.3 538322 538846 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 538322..538846 Bacillus subtilis subsp. subtilis str. 168 939921 NP_388375.2 CDS yddE NC_000964.3 538836 541229 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 538836..541229 Bacillus subtilis subsp. subtilis str. 168 938130 NP_388376.1 CDS yddF NC_000964.3 541248 541574 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 541248..541574 Bacillus subtilis subsp. subtilis str. 168 938143 NP_388377.1 CDS yddG NC_000964.3 541578 544025 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 541578..544025 Bacillus subtilis subsp. subtilis str. 168 938141 NP_388378.1 CDS yddH NC_000964.3 544022 545011 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; endopeptidase YddH 544022..545011 Bacillus subtilis subsp. subtilis str. 168 938136 NP_388379.1 CDS yddI NC_000964.3 545026 545532 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 545026..545532 Bacillus subtilis subsp. subtilis str. 168 939919 NP_388380.1 CDS yddJ NC_000964.3 545595 545975 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 545595..545975 Bacillus subtilis subsp. subtilis str. 168 939925 NP_388381.1 CDS yddK NC_000964.3 546166 546966 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(546166..546966) Bacillus subtilis subsp. subtilis str. 168 939917 NP_388382.1 CDS rapI NC_000964.3 547306 548481 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16105942; Product type r: regulator; response regulator aspartate phosphatase I 547306..548481 Bacillus subtilis subsp. subtilis str. 168 938127 NP_388383.1 CDS phrI NC_000964.3 548438 548557 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type r: regulator; secreted regulator of the activity of phosphatase RapI 548438..548557 Bacillus subtilis subsp. subtilis str. 168 939927 NP_388384.1 CDS yddM NC_000964.3 548710 549651 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; helicase 548710..549651 Bacillus subtilis subsp. subtilis str. 168 938134 NP_388385.1 CDS yddN NC_000964.3 550240 551259 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme; hypothetical protein complement(550240..551259) Bacillus subtilis subsp. subtilis str. 168 938133 NP_388386.1 CDS lrpA NC_000964.3 551519 551929 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator; AsnC family transcriptional regulator 551519..551929 Bacillus subtilis subsp. subtilis str. 168 938119 NP_388387.1 CDS lrpB NC_000964.3 552052 552501 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator; AsnC family transcriptional regulator complement(552052..552501) Bacillus subtilis subsp. subtilis str. 168 939912 NP_388388.1 CDS yddQ NC_000964.3 552616 553158 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase 552616..553158 Bacillus subtilis subsp. subtilis str. 168 938129 NP_388389.1 CDS yddR NC_000964.3 553711 554475 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 553711..554475 Bacillus subtilis subsp. subtilis str. 168 939915 NP_388390.1 CDS yddS NC_000964.3 554669 555979 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 554669..555979 Bacillus subtilis subsp. subtilis str. 168 938128 YP_003097682.1 CDS ydzM NC_000964.3 556562 556738 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 556562..556738 Bacillus subtilis subsp. subtilis str. 168 8303141 NP_388391.1 CDS yddT NC_000964.3 556763 557449 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 556763..557449 Bacillus subtilis subsp. subtilis str. 168 939913 YP_003097683.1 CDS ydzN NC_000964.3 557873 558058 D Evidence 5: No homology to any previously reported sequences; membrane protein 557873..558058 Bacillus subtilis subsp. subtilis str. 168 8303142 NP_388392.1 CDS ydeA NC_000964.3 558408 559001 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YdeA 558408..559001 Bacillus subtilis subsp. subtilis str. 168 939914 NP_388393.1 CDS cspC NC_000964.3 559264 559464 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10517332, 12427936, 9914312, 9920884; Product type f: factor; cold shock protein CspC 559264..559464 Bacillus subtilis subsp. subtilis str. 168 938114 NP_388394.1 CDS ydeB NC_000964.3 560151 560612 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcription factor YdeB complement(560151..560612) Bacillus subtilis subsp. subtilis str. 168 938120 NP_388395.1 CDS ydzE NC_000964.3 561180 561416 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; permease complement(561180..561416) Bacillus subtilis subsp. subtilis str. 168 938121 NP_388396.1 CDS ydeC NC_000964.3 561514 562389 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator complement(561514..562389) Bacillus subtilis subsp. subtilis str. 168 938103 NP_388397.1 CDS ydeD NC_000964.3 562502 563461 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 562502..563461 Bacillus subtilis subsp. subtilis str. 168 939906 NP_388398.1 CDS ydeE NC_000964.3 563614 564486 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator complement(563614..564486) Bacillus subtilis subsp. subtilis str. 168 938117 NP_388399.1 CDS ydeF NC_000964.3 564704 566101 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 564704..566101 Bacillus subtilis subsp. subtilis str. 168 939911 NP_388400.1 CDS ydeG NC_000964.3 566211 567503 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 566211..567503 Bacillus subtilis subsp. subtilis str. 168 938115 NP_388401.1 CDS ydeH NC_000964.3 567662 568108 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 567662..568108 Bacillus subtilis subsp. subtilis str. 168 938097 NP_388402.1 CDS ydeI NC_000964.3 568345 568938 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 568345..568938 Bacillus subtilis subsp. subtilis str. 168 939916 NP_388403.1 CDS ydeJ NC_000964.3 569290 569949 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein complement(569290..569949) Bacillus subtilis subsp. subtilis str. 168 939910 NP_388404.1 CDS ydeK NC_000964.3 570371 571234 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(570371..571234) Bacillus subtilis subsp. subtilis str. 168 938112 NP_388405.1 CDS ydeL NC_000964.3 571389 572780 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 571389..572780 Bacillus subtilis subsp. subtilis str. 168 939904 NP_388406.1 CDS ydeM NC_000964.3 572974 573399 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1556068; Product type pe : enzyme; hypothetical protein 572974..573399 Bacillus subtilis subsp. subtilis str. 168 938104 NP_388407.1 CDS ydeN NC_000964.3 573452 574024 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15159570; Product type e: enzyme; hydrolase complement(573452..574024) Bacillus subtilis subsp. subtilis str. 168 939908 NP_388408.1 CDS ydzF NC_000964.3 574106 574435 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator complement(574106..574435) Bacillus subtilis subsp. subtilis str. 168 938088 NP_388409.1 CDS ydeO NC_000964.3 574690 575562 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 574690..575562 Bacillus subtilis subsp. subtilis str. 168 938098 NP_388410.1 CDS ydeP NC_000964.3 575712 576098 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator complement(575712..576098) Bacillus subtilis subsp. subtilis str. 168 938100 NP_388411.1 CDS ydeQ NC_000964.3 576209 576802 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H oxidoreductase 576209..576802 Bacillus subtilis subsp. subtilis str. 168 939902 NP_388412.1 CDS ydeR NC_000964.3 576946 578133 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(576946..578133) Bacillus subtilis subsp. subtilis str. 168 938096 NP_388413.1 CDS ydeS NC_000964.3 578337 578933 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator; TetR family transcriptional regulator 578337..578933 Bacillus subtilis subsp. subtilis str. 168 938083 YP_003097684.1 CDS ydzO NC_000964.3 579047 579232 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 579047..579232 Bacillus subtilis subsp. subtilis str. 168 8303150 NP_388414.1 CDS aseR NC_000964.3 579541 579876 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator; ArsR family transcriptional regulator 579541..579876 Bacillus subtilis subsp. subtilis str. 168 938089 NP_388415.1 CDS ydfA NC_000964.3 579889 581196 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; arsenic pump protein 579889..581196 Bacillus subtilis subsp. subtilis str. 168 939905 NP_388416.1 CDS ydfB NC_000964.3 581694 582479 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; N-acetyltransferase YdfB 581694..582479 Bacillus subtilis subsp. subtilis str. 168 938079 NP_388417.1 CDS ydfC NC_000964.3 582536 583456 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(582536..583456) Bacillus subtilis subsp. subtilis str. 168 938086 NP_388418.1 CDS ydfD NC_000964.3 583589 585037 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 583589..585037 Bacillus subtilis subsp. subtilis str. 168 939903 NP_388419.1 CDS ydfE NC_000964.3 585155 585778 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(585155..585778) Bacillus subtilis subsp. subtilis str. 168 939898 NP_388420.1 CDS ydfF NC_000964.3 585868 586548 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 585868..586548 Bacillus subtilis subsp. subtilis str. 168 938084 NP_388421.1 CDS ydfG NC_000964.3 586628 587071 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(586628..587071) Bacillus subtilis subsp. subtilis str. 168 938081 YP_003097685.1 CDS ydzP NC_000964.3 587157 587336 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(587157..587336) Bacillus subtilis subsp. subtilis str. 168 8302941 YP_003097686.1 CDS ydzQ NC_000964.3 587333 587476 R Evidence 6: Doubtful CDS; hypothetical protein complement(587333..587476) Bacillus subtilis subsp. subtilis str. 168 8303032 NP_388422.1 CDS ydfH NC_000964.3 587744 588967 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type rc: receptor; sensor histidine kinase 587744..588967 Bacillus subtilis subsp. subtilis str. 168 938076 NP_388423.1 CDS ydfI NC_000964.3 588960 589601 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type r: regulator; transcriptional regulator 588960..589601 Bacillus subtilis subsp. subtilis str. 168 938080 NP_388424.1 CDS ydfJ NC_000964.3 589717 591891 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pt : transporter; membrane protein 589717..591891 Bacillus subtilis subsp. subtilis str. 168 939901 NP_388425.1 CDS nap NC_000964.3 592303 593205 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7765103; Product type e : enzyme; carboxylesterase nap complement(592303..593205) Bacillus subtilis subsp. subtilis str. 168 938069 NP_388426.1 CDS ydfK NC_000964.3 593407 594096 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10200972, 15849754, 16850406; Product type pm: membrane component; membrane protein complement(593407..594096) Bacillus subtilis subsp. subtilis str. 168 939896 NP_388427.1 CDS ydfL NC_000964.3 594186 594998 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator complement(594186..594998) Bacillus subtilis subsp. subtilis str. 168 938078 NP_388428.2 CDS ydfM NC_000964.3 595109 596002 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter complement(595109..596002) Bacillus subtilis subsp. subtilis str. 168 939900 NP_388429.1 CDS ydfN NC_000964.3 596478 597098 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; NAD(P)H nitroreductase MhqN 596478..597098 Bacillus subtilis subsp. subtilis str. 168 939899 NP_388430.1 CDS ydfO NC_000964.3 597114 598052 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqO 597114..598052 Bacillus subtilis subsp. subtilis str. 168 939894 NP_388431.1 CDS ydfP NC_000964.3 598154 598543 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15306018, 15849754, 16850406, 17407181; Product type pe: enzyme; oxidoreductase 598154..598543 Bacillus subtilis subsp. subtilis str. 168 938077 NP_388432.1 CDS ydfQ NC_000964.3 598729 599067 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; thioredoxin 598729..599067 Bacillus subtilis subsp. subtilis str. 168 938062 NP_388433.1 CDS ydzH NC_000964.3 599107 599343 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(599107..599343) Bacillus subtilis subsp. subtilis str. 168 938074 YP_003097687.1 CDS ydzR NC_000964.3 599875 600105 R Evidence 4: Homologs of previously reported genes of unknown function; spore germination protein complement(599875..600105) Bacillus subtilis subsp. subtilis str. 168 8303211 NP_388434.1 CDS ydfR NC_000964.3 600229 600906 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(600229..600906) Bacillus subtilis subsp. subtilis str. 168 939897 NP_388435.1 CDS ydfS NC_000964.3 601019 601726 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 601019..601726 Bacillus subtilis subsp. subtilis str. 168 939890 NP_388436.1 CDS cotP NC_000964.3 601741 602172 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673; Product type f: factor; spore coat protein P complement(601741..602172) Bacillus subtilis subsp. subtilis str. 168 938073 NP_388437.1 CDS ydgA NC_000964.3 602185 602427 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(602185..602427) Bacillus subtilis subsp. subtilis str. 168 938065 NP_388438.1 CDS ydgB NC_000964.3 602441 602713 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(602441..602713) Bacillus subtilis subsp. subtilis str. 168 938056 NP_388439.1 CDS ydgC NC_000964.3 603012 603599 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 603012..603599 Bacillus subtilis subsp. subtilis str. 168 938064 NP_388440.1 CDS ydgD NC_000964.3 603596 603940 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 603596..603940 Bacillus subtilis subsp. subtilis str. 168 939895 NP_388441.1 CDS ydgE NC_000964.3 604103 604576 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YdgE 604103..604576 Bacillus subtilis subsp. subtilis str. 168 939907 NP_388442.1 CDS vmlR NC_000964.3 604736 606379 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16109936; Product type t: transporter; nucleotide-binding protein ExpZ complement(604736..606379) Bacillus subtilis subsp. subtilis str. 168 938053 NP_388443.1 CDS ydgF NC_000964.3 606699 608075 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16109936, 16850406; Product type pt: transporter; transporter complement(606699..608075) Bacillus subtilis subsp. subtilis str. 168 938050 NP_388444.1 CDS dinB NC_000964.3 608246 608764 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12644484, 16267290; Product type r : regulator; protein DinB complement(608246..608764) Bacillus subtilis subsp. subtilis str. 168 938057 NP_388445.1 CDS ydgG NC_000964.3 608933 609391 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 608933..609391 Bacillus subtilis subsp. subtilis str. 168 939880 NP_388446.1 CDS ydgH NC_000964.3 609388 612045 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pm : membrane component; membrane protein 609388..612045 Bacillus subtilis subsp. subtilis str. 168 938043 NP_388447.1 CDS ydgI NC_000964.3 612191 612820 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H nitroreductase YdgI complement(612191..612820) Bacillus subtilis subsp. subtilis str. 168 938001 NP_388448.1 CDS ydgJ NC_000964.3 612836 613330 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator complement(612836..613330) Bacillus subtilis subsp. subtilis str. 168 938036 NP_388449.1 CDS ydgK NC_000964.3 613641 614849 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 613641..614849 Bacillus subtilis subsp. subtilis str. 168 938060 NP_388450.2 CDS ydhB NC_000964.3 614885 615622 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(614885..615622) Bacillus subtilis subsp. subtilis str. 168 939893 NP_388451.1 CDS ydhC NC_000964.3 615871 616545 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 615871..616545 Bacillus subtilis subsp. subtilis str. 168 938042 NP_388452.2 CDS ydhD NC_000964.3 616672 617934 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11011148, 12177332; Product type cp: cell process; sporulation protein 616672..617934 Bacillus subtilis subsp. subtilis str. 168 939885 NP_388453.2 CDS ydhE NC_000964.3 618095 619282 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YdhE 618095..619282 Bacillus subtilis subsp. subtilis str. 168 939868 NP_388454.1 CDS ydhF NC_000964.3 619321 620031 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557812; Product type lp : lipoprotein; hypothetical protein complement(619321..620031) Bacillus subtilis subsp. subtilis str. 168 938019 NP_388455.2 CDS phoB NC_000964.3 620097 621485 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 16030210, 16491025, 9335276; Product type e: enzyme; alkaline phosphatase 3 complement(620097..621485) Bacillus subtilis subsp. subtilis str. 168 938004 NP_388456.1 CDS ydhG NC_000964.3 621847 622218 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 621847..622218 Bacillus subtilis subsp. subtilis str. 168 938031 NP_388457.1 CDS ydhH NC_000964.3 622293 622790 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(622293..622790) Bacillus subtilis subsp. subtilis str. 168 939877 NP_388458.1 CDS ydhI NC_000964.3 622808 623290 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(622808..623290) Bacillus subtilis subsp. subtilis str. 168 939866 NP_388459.1 CDS ydhJ NC_000964.3 623373 624350 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 623373..624350 Bacillus subtilis subsp. subtilis str. 168 938014 NP_388460.1 CDS ydhK NC_000964.3 624492 625109 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 624492..625109 Bacillus subtilis subsp. subtilis str. 168 939873 NP_388461.2 CDS pbuE NC_000964.3 625125 626291 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12923093, 15849754, 16850406, 17935948; Product type t: transporter; purine efflux pump PbuE complement(625125..626291) Bacillus subtilis subsp. subtilis str. 168 937996 NP_388462.1 CDS gmuB NC_000964.3 626622 626933 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 18177310; Product type t: transporter; PTS system oligo-beta-mannoside transporter subunit IIB 626622..626933 Bacillus subtilis subsp. subtilis str. 168 938018 NP_388463.2 CDS gmuA NC_000964.3 626933 627265 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; PTS system oligo-beta-mannoside transporter subunit IIA 626933..627265 Bacillus subtilis subsp. subtilis str. 168 938039 NP_388464.1 CDS gmuC NC_000964.3 627284 628612 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 18177310; Product type t : transporter; PTS system oligo-beta-mannoside transporter subunit IIC 627284..628612 Bacillus subtilis subsp. subtilis str. 168 939882 NP_388465.1 CDS gmuD NC_000964.3 628630 630027 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18177310; Product type e: enzyme; 6-phospho-beta-glucosidase GmuD 628630..630027 Bacillus subtilis subsp. subtilis str. 168 939872 NP_388466.1 CDS gmuR NC_000964.3 630170 630883 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310; Product type r: regulator; GntR family transcriptional regulator 630170..630883 Bacillus subtilis subsp. subtilis str. 168 939879 NP_388467.1 CDS gmuE NC_000964.3 630912 631811 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15018644, 18177310; Product type pe: enzyme; fructokinase 630912..631811 Bacillus subtilis subsp. subtilis str. 168 938016 NP_388468.1 CDS gmuF NC_000964.3 631808 632755 D Evidence 2b: Function of strongly homologous gene; PubMedId: 10704478, 18177310, 3017192; Product type e: enzyme; mannose-6-phosphate isomerase GmuF 631808..632755 Bacillus subtilis subsp. subtilis str. 168 938028 NP_388469.2 CDS gmuG NC_000964.3 632774 633862 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310, 2694961, 7727534; Product type e: enzyme; mannan endo-1,4-beta-mannosidase 632774..633862 Bacillus subtilis subsp. subtilis str. 168 938034 NP_388471.1 CDS thiL NC_000964.3 640662 641639 D catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine-monophosphate kinase 640662..641639 Bacillus subtilis subsp. subtilis str. 168 939867 NP_388472.1 CDS ydiB NC_000964.3 641654 642130 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pe: enzyme; UPF0079 ATP-binding protein YdiB 641654..642130 Bacillus subtilis subsp. subtilis str. 168 938047 NP_388473.1 CDS ydiC NC_000964.3 642111 642800 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pf: factor; hypothetical protein 642111..642800 Bacillus subtilis subsp. subtilis str. 168 939874 NP_388474.1 CDS rimI NC_000964.3 642810 643265 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2828880; Product type e: enzyme; ribosomal-protein-alanine acetyltransferase 642810..643265 Bacillus subtilis subsp. subtilis str. 168 937997 NP_388475.1 CDS gcp NC_000964.3 643258 644298 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; tRNA threonylcarbamoyladenosine biosynthesis protein Gcp 643258..644298 Bacillus subtilis subsp. subtilis str. 168 938020 NP_388476.2 CDS ydiF NC_000964.3 644528 646456 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11916677; Product type pt : transporter; ABC transporter ATP-binding protein complement(644528..646456) Bacillus subtilis subsp. subtilis str. 168 938013 NP_388477.1 CDS moaC NC_000964.3 646582 647094 D MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; cyclic pyranopterin monophosphate synthase accessory protein 646582..647094 Bacillus subtilis subsp. subtilis str. 168 939875 NP_388478.1 CDS ydiH NC_000964.3 647091 647738 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor rex 647091..647738 Bacillus subtilis subsp. subtilis str. 168 939871 NP_388479.1 CDS tatAY NC_000964.3 647760 647933 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatAy 647760..647933 Bacillus subtilis subsp. subtilis str. 168 939878 NP_388480.1 CDS tatCY NC_000964.3 647940 648704 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775, 15187182, 15849754, 16850406, 19049517; Product type t : transporter; Sec-independent protein translocase protein TatCy 647940..648704 Bacillus subtilis subsp. subtilis str. 168 938010 NP_388481.1 CDS ydiK NC_000964.3 648742 648933 R Evidence 4: Homologs of previously reported genes of unknown function; lipoprotein complement(648742..648933) Bacillus subtilis subsp. subtilis str. 168 939870 NP_388482.1 CDS ydiL NC_000964.3 648930 649664 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane peptidase YdiL complement(648930..649664) Bacillus subtilis subsp. subtilis str. 168 938033 NP_388483.2 CDS groES NC_000964.3 649903 650187 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; 10 kDa chaperonin 649903..650187 Bacillus subtilis subsp. subtilis str. 168 938006 NP_388484.1 CDS groEL NC_000964.3 650234 651868 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; 60 kDa chaperonin 650234..651868 Bacillus subtilis subsp. subtilis str. 168 938045 NP_388485.1 CDS ydiM NC_000964.3 653432 653812 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 653432..653812 Bacillus subtilis subsp. subtilis str. 168 939886 YP_003097688.1 CDS ydzU NC_000964.3 654071 654343 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 654071..654343 Bacillus subtilis subsp. subtilis str. 168 8302904 NP_388487.1 CDS ydiO NC_000964.3 655223 656506 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 12682299, 16014871, 16267290; Product type e: enzyme; BsuMI modification methylase subunit YdiO 655223..656506 Bacillus subtilis subsp. subtilis str. 168 939892 NP_388488.1 CDS ydiP NC_000964.3 656528 657697 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 16267290; Product type e: enzyme; BsuMI modification methylase subunit YdiP 656528..657697 Bacillus subtilis subsp. subtilis str. 168 939876 NP_388490.1 CDS ydiR NC_000964.3 659623 660564 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 15728999; Product type h: extrachromosomal origin; type-2 restriction enzyme BsuMI component YdiR 659623..660564 Bacillus subtilis subsp. subtilis str. 168 938002 NP_388491.1 CDS ydiS NC_000964.3 660596 661627 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme; type-2 restriction enzyme BsuMI component YdiS 660596..661627 Bacillus subtilis subsp. subtilis str. 168 938023 NP_388492.1 CDS ydjA NC_000964.3 661630 663027 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme; type-2 restriction enzyme BsuMI component YdjA 661630..663027 Bacillus subtilis subsp. subtilis str. 168 939884 NP_388493.1 CDS ydjB NC_000964.3 663601 663936 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 663601..663936 Bacillus subtilis subsp. subtilis str. 168 935917 NP_388494.1 CDS ydjC NC_000964.3 664319 664669 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 664319..664669 Bacillus subtilis subsp. subtilis str. 168 936012 NP_388495.1 CDS gutR NC_000964.3 664775 667264 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11118449, 11390381, 12897001; Product type r: regulator; transcription activator GutR complement(664775..667264) Bacillus subtilis subsp. subtilis str. 168 938026 NP_388496.1 CDS gutB NC_000964.3 667466 668527 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme; sorbitol dehydrogenase 667466..668527 Bacillus subtilis subsp. subtilis str. 168 939495 NP_388497.1 CDS gutP NC_000964.3 668601 669992 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12897001; Product type t: transporter; glucitol transport protein GutA 668601..669992 Bacillus subtilis subsp. subtilis str. 168 936004 NP_388498.1 CDS ydjE NC_000964.3 670087 671049 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; sugar kinase YdjE 670087..671049 Bacillus subtilis subsp. subtilis str. 168 939494 NP_388499.1 CDS pspA NC_000964.3 671245 671928 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11454200; Product type h: extrachromosomal origin; phage shock protein A homolog 671245..671928 Bacillus subtilis subsp. subtilis str. 168 936013 NP_388500.1 CDS ydjG NC_000964.3 671994 673019 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 671994..673019 Bacillus subtilis subsp. subtilis str. 168 939489 NP_388501.1 CDS ydjH NC_000964.3 673019 673783 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 673019..673783 Bacillus subtilis subsp. subtilis str. 168 936015 NP_388502.1 CDS ydjI NC_000964.3 673814 674785 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 673814..674785 Bacillus subtilis subsp. subtilis str. 168 939493 NP_388503.1 CDS ydjJ NC_000964.3 674832 675857 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; membrane protein complement(674832..675857) Bacillus subtilis subsp. subtilis str. 168 936027 NP_388504.1 CDS iolT NC_000964.3 676442 677863 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter; major myo-inositol transporter IolT 676442..677863 Bacillus subtilis subsp. subtilis str. 168 936014 NP_388505.1 CDS bdhA NC_000964.3 677911 678951 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 18820069; Product type e: enzyme; (r,r)-butanediol dehydrogenase complement(677911..678951) Bacillus subtilis subsp. subtilis str. 168 939490 NP_388506.1 CDS ydjM NC_000964.3 679390 679761 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 679390..679761 Bacillus subtilis subsp. subtilis str. 168 936017 NP_388507.1 CDS ydjN NC_000964.3 679827 680873 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 679827..680873 Bacillus subtilis subsp. subtilis str. 168 939488 YP_003097689.1 CDS ydzJ NC_000964.3 680907 681065 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(680907..681065) Bacillus subtilis subsp. subtilis str. 168 8303125 NP_388508.1 CDS ydjO NC_000964.3 681255 681464 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(681255..681464) Bacillus subtilis subsp. subtilis str. 168 936021 NP_388509.1 CDS ydjP NC_000964.3 681547 682362 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pe : enzyme; AB hydrolase superfamily protein YdjP complement(681547..682362) Bacillus subtilis subsp. subtilis str. 168 936035 NP_388510.1 CDS yeaA NC_000964.3 682375 683364 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(682375..683364) Bacillus subtilis subsp. subtilis str. 168 936018 NP_388511.1 CDS cotA NC_000964.3 683462 685003 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11514528, 12637519, 16391148, 17242517, 18031270; Product type e: enzyme; spore coat protein A complement(683462..685003) Bacillus subtilis subsp. subtilis str. 168 936023 NP_388512.2 CDS gabP NC_000964.3 685155 686564 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16547045, 16850406, 8951816, 9677314; Product type t: transporter; GABA permease complement(685155..686564) Bacillus subtilis subsp. subtilis str. 168 939485 YP_003097690.1 CDS ydzX NC_000964.3 686602 686889 R Evidence 6: Doubtful CDS; hypothetical protein complement(686602..686889) Bacillus subtilis subsp. subtilis str. 168 8303160 NP_388513.1 CDS yeaB NC_000964.3 686962 687834 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter 686962..687834 Bacillus subtilis subsp. subtilis str. 168 936032 NP_388514.2 CDS yeaC NC_000964.3 688184 689146 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 688184..689146 Bacillus subtilis subsp. subtilis str. 168 939484 NP_388515.2 CDS yeaD NC_000964.3 689146 690342 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 689146..690342 Bacillus subtilis subsp. subtilis str. 168 939486 NP_388516.2 CDS yebA NC_000964.3 690364 692577 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 690364..692577 Bacillus subtilis subsp. subtilis str. 168 936029 NP_388517.2 CDS guaA NC_000964.3 692740 694281 D contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 692740..694281 Bacillus subtilis subsp. subtilis str. 168 936028 NP_388518.1 CDS pbuG NC_000964.3 694662 695984 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12923093, 15849754, 16850406, 3110131; Product type t : transporter; guanine/hypoxanthine permease PbuG 694662..695984 Bacillus subtilis subsp. subtilis str. 168 936043 NP_388519.2 CDS yebC NC_000964.3 696195 696998 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 696195..696998 Bacillus subtilis subsp. subtilis str. 168 939478 NP_388520.3 CDS yebD NC_000964.3 697157 697324 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 697157..697324 Bacillus subtilis subsp. subtilis str. 168 936033 NP_388521.2 CDS yebE NC_000964.3 697538 698092 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 697538..698092 Bacillus subtilis subsp. subtilis str. 168 939480 NP_388523.1 CDS yebG NC_000964.3 698092 698289 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 698092..698289 Bacillus subtilis subsp. subtilis str. 168 939351 NP_388524.1 CDS purE NC_000964.3 698612 699100 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12787499, 16138311, 9683488; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase 698612..699100 Bacillus subtilis subsp. subtilis str. 168 939481 NP_388525.2 CDS purK NC_000964.3 699093 700235 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; N5-carboxyaminoimidazole ribonucleotide synthase 699093..700235 Bacillus subtilis subsp. subtilis str. 168 936039 NP_388526.1 CDS purB NC_000964.3 700232 701527 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 700232..701527 Bacillus subtilis subsp. subtilis str. 168 936048 NP_388527.1 CDS purC NC_000964.3 701601 702326 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 701601..702326 Bacillus subtilis subsp. subtilis str. 168 939389 NP_388528.1 CDS purS NC_000964.3 702319 702573 D With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; hypothetical protein 702319..702573 Bacillus subtilis subsp. subtilis str. 168 936041 NP_388529.1 CDS purQ NC_000964.3 702570 703253 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 702570..703253 Bacillus subtilis subsp. subtilis str. 168 938760 NP_388530.2 CDS purL NC_000964.3 703237 705465 D catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 703237..705465 Bacillus subtilis subsp. subtilis str. 168 939233 NP_388531.2 CDS purF NC_000964.3 705441 706871 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 705441..706871 Bacillus subtilis subsp. subtilis str. 168 936046 NP_388532.2 CDS purM NC_000964.3 706973 708013 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylformylglycinamidine cyclo-ligase 706973..708013 Bacillus subtilis subsp. subtilis str. 168 936044 NP_388533.2 CDS purN NC_000964.3 708010 708597 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 708010..708597 Bacillus subtilis subsp. subtilis str. 168 936045 NP_388534.2 CDS purH NC_000964.3 708594 710132 D involved in de novo purine biosynthesis; bifunctional purine biosynthesis protein PurH 708594..710132 Bacillus subtilis subsp. subtilis str. 168 936053 NP_388535.1 CDS purD NC_000964.3 710148 711416 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 710148..711416 Bacillus subtilis subsp. subtilis str. 168 938741 NP_388536.2 CDS yezC NC_000964.3 711456 711875 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AsnC family transcriptional regulator complement(711456..711875) Bacillus subtilis subsp. subtilis str. 168 936047 NP_388537.2 CDS yecA NC_000964.3 712019 713293 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid permease 712019..713293 Bacillus subtilis subsp. subtilis str. 168 936051 YP_003097691.1 CDS yezF NC_000964.3 713308 713535 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(713308..713535) Bacillus subtilis subsp. subtilis str. 168 8302929 NP_388538.1 CDS yerA NC_000964.3 713664 715406 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; adenine deaminase YerA 713664..715406 Bacillus subtilis subsp. subtilis str. 168 939337 NP_388539.1 CDS yerB NC_000964.3 715433 716428 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12073041; Product type lp : lipoprotein; lipoprotein 715433..716428 Bacillus subtilis subsp. subtilis str. 168 936050 NP_388540.1 CDS yerC NC_000964.3 716431 716745 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 716431..716745 Bacillus subtilis subsp. subtilis str. 168 936049 NP_388541.1 CDS yerD NC_000964.3 716780 718357 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glutamate synthase large subunit-like protein YerD complement(716780..718357) Bacillus subtilis subsp. subtilis str. 168 936058 NP_388542.1 CDS pcrB NC_000964.3 718622 719308 D PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer; heptaprenylglyceryl phosphate synthase 718622..719308 Bacillus subtilis subsp. subtilis str. 168 936052 NP_388543.1 CDS pcrA NC_000964.3 719370 721589 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 12682299, 14594837, 16267290; Product type e: enzyme; ATP-dependent DNA helicase PcrA 719370..721589 Bacillus subtilis subsp. subtilis str. 168 938747 NP_388544.1 CDS ligA NC_000964.3 721613 723619 D this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; DNA ligase 721613..723619 Bacillus subtilis subsp. subtilis str. 168 936056 NP_388545.1 CDS yerH NC_000964.3 723635 724825 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type lp : lipoprotein; lipoprotein 723635..724825 Bacillus subtilis subsp. subtilis str. 168 938744 NP_388546.1 CDS yerI NC_000964.3 724987 725997 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 724987..725997 Bacillus subtilis subsp. subtilis str. 168 936055 NP_388547.1 CDS sapB NC_000964.3 726035 726733 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14708580, 410907, 9043134; Product type ph: phenotype; peptide ABC transporter permease SapB complement(726035..726733) Bacillus subtilis subsp. subtilis str. 168 936054 NP_388548.1 CDS opuE NC_000964.3 726840 728318 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902719, 14996799, 15849754, 16850406, 17183215, 9701821; Product type t : transporter; osmoregulated proline transporter complement(726840..728318) Bacillus subtilis subsp. subtilis str. 168 939439 NP_388549.1 CDS gatC NC_000964.3 728732 729022 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; glutamyl-tRNA(Gln) amidotransferase subunit C 728732..729022 Bacillus subtilis subsp. subtilis str. 168 936063 NP_388550.1 CDS gatA NC_000964.3 729038 730495 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; glutamyl-tRNA(Gln) amidotransferase subunit A 729038..730495 Bacillus subtilis subsp. subtilis str. 168 938748 NP_388551.2 CDS gatB NC_000964.3 730509 731939 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 730509..731939 Bacillus subtilis subsp. subtilis str. 168 936057 NP_388552.1 CDS yerO NC_000964.3 731954 732823 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator complement(731954..732823) Bacillus subtilis subsp. subtilis str. 168 939889 NP_388553.1 CDS swrC NC_000964.3 732916 736113 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11709341, 15066026, 15941986; Product type t: transporter; surfactin self-resistance transporter 732916..736113 Bacillus subtilis subsp. subtilis str. 168 938055 NP_388554.1 CDS yerQ NC_000964.3 736436 737347 D similar to YegS from E. coli; diacylglycerol kinase 736436..737347 Bacillus subtilis subsp. subtilis str. 168 936061 NP_388555.1 CDS yefA NC_000964.3 737603 738982 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 23S rRNA (uracil-C(5))-methyltransferase RlmCD 737603..738982 Bacillus subtilis subsp. subtilis str. 168 936060 NP_388556.1 CDS yefB NC_000964.3 738995 739897 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(738995..739897) Bacillus subtilis subsp. subtilis str. 168 938745 NP_388557.2 CDS yefC NC_000964.3 739878 740213 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; resolvase homolog YefC 739878..740213 Bacillus subtilis subsp. subtilis str. 168 938743 NP_388558.1 CDS yeeA NC_000964.3 740288 742927 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA methyltransferase YeeA 740288..742927 Bacillus subtilis subsp. subtilis str. 168 936059 NP_388559.2 CDS yeeB NC_000964.3 742939 744738 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YeeB 742939..744738 Bacillus subtilis subsp. subtilis str. 168 936068 NP_388560.2 CDS yeeC NC_000964.3 744851 745999 D Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin; hypothetical protein 744851..745999 Bacillus subtilis subsp. subtilis str. 168 936062 NP_388561.1 CDS yeeD NC_000964.3 746261 746566 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(746261..746566) Bacillus subtilis subsp. subtilis str. 168 938755 NP_388562.1 CDS yezA NC_000964.3 746633 746839 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(746633..746839) Bacillus subtilis subsp. subtilis str. 168 938751 YP_003097692.1 CDS yezG NC_000964.3 747079 747534 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(747079..747534) Bacillus subtilis subsp. subtilis str. 168 8303066 NP_388563.2 CDS yeeF NC_000964.3 747554 749563 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(747554..749563) Bacillus subtilis subsp. subtilis str. 168 938753 NP_388564.2 CDS yeeG NC_000964.3 749775 750797 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 749775..750797 Bacillus subtilis subsp. subtilis str. 168 938041 NP_388565.2 CDS rapH NC_000964.3 750959 752089 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878; Product type e: enzyme; response regulator aspartate phosphatase H 750959..752089 Bacillus subtilis subsp. subtilis str. 168 936065 YP_003097693.1 CDS phrH NC_000964.3 752079 752252 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16553878; Product type pf : factor; inhibitor of regulatory cascade 752079..752252 Bacillus subtilis subsp. subtilis str. 168 8303115 NP_388566.3 CDS yeeI NC_000964.3 752412 753131 D Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator 752412..753131 Bacillus subtilis subsp. subtilis str. 168 938749 NP_388567.2 CDS yeeK NC_000964.3 753265 753702 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 19060142; Product type cp: cell process; spore coat protein YeeK 753265..753702 Bacillus subtilis subsp. subtilis str. 168 936073 YP_054572.1 CDS yezE NC_000964.3 753817 754401 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 753817..754401 Bacillus subtilis subsp. subtilis str. 168 2914263 NP_388568.1 CDS yesE NC_000964.3 754480 754923 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 754480..754923 Bacillus subtilis subsp. subtilis str. 168 936064 NP_388569.1 CDS yesF NC_000964.3 754920 755780 D Evidence 4: Homologs of previously reported genes of unknown function; oxidoreductase 754920..755780 Bacillus subtilis subsp. subtilis str. 168 936067 NP_388570.1 CDS cotJA NC_000964.3 755907 756155 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat associated protein CotJA 755907..756155 Bacillus subtilis subsp. subtilis str. 168 938758 NP_388571.2 CDS cotJB NC_000964.3 756139 756402 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat protein CotJB 756139..756402 Bacillus subtilis subsp. subtilis str. 168 936071 NP_388572.1 CDS cotJC NC_000964.3 756417 756986 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat peptide assembly protein CotJC 756417..756986 Bacillus subtilis subsp. subtilis str. 168 938762 NP_388573.1 CDS yesJ NC_000964.3 757111 757653 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YesJ 757111..757653 Bacillus subtilis subsp. subtilis str. 168 936070 NP_388574.2 CDS yesK NC_000964.3 757676 757978 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 757676..757978 Bacillus subtilis subsp. subtilis str. 168 936069 NP_388575.1 CDS yesL NC_000964.3 758093 758722 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 758093..758722 Bacillus subtilis subsp. subtilis str. 168 938754 NP_388576.1 CDS yesM NC_000964.3 758719 760452 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 758719..760452 Bacillus subtilis subsp. subtilis str. 168 936078 NP_388577.1 CDS yesN NC_000964.3 760452 761558 D Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; transcriptional regulator 760452..761558 Bacillus subtilis subsp. subtilis str. 168 938764 NP_388578.2 CDS yesO NC_000964.3 761662 762945 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein; ABC transporter substrate-binding protein 761662..762945 Bacillus subtilis subsp. subtilis str. 168 936072 NP_388579.1 CDS yesP NC_000964.3 762942 763871 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter; ABC transporter permease 762942..763871 Bacillus subtilis subsp. subtilis str. 168 936076 NP_388580.1 CDS yesQ NC_000964.3 763875 764765 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter; ABC transporter permease 763875..764765 Bacillus subtilis subsp. subtilis str. 168 938765 NP_388581.1 CDS yesR NC_000964.3 764781 765815 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonyl hydrolase 764781..765815 Bacillus subtilis subsp. subtilis str. 168 938759 NP_388582.1 CDS yesS NC_000964.3 765838 768123 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type r: regulator; AraC family transcriptional regulator 765838..768123 Bacillus subtilis subsp. subtilis str. 168 936075 NP_388583.1 CDS rhgT NC_000964.3 768137 768835 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691, 17957779; Product type e: enzyme; rhamnogalacturonan acetylesterase RhgT 768137..768835 Bacillus subtilis subsp. subtilis str. 168 936074 NP_388584.1 CDS yesU NC_000964.3 768828 769490 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691; hypothetical protein 768828..769490 Bacillus subtilis subsp. subtilis str. 168 936083 NP_388585.1 CDS yesV NC_000964.3 769487 770113 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pm: membrane component; hypothetical protein 769487..770113 Bacillus subtilis subsp. subtilis str. 168 936077 NP_388586.1 CDS yesW NC_000964.3 770234 772096 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein; rhamnogalacturonan endolyase YesW 770234..772096 Bacillus subtilis subsp. subtilis str. 168 938769 NP_388587.1 CDS yesX NC_000964.3 772142 773980 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonan exolyase YesX 772142..773980 Bacillus subtilis subsp. subtilis str. 168 936081 NP_388588.1 CDS yesY NC_000964.3 774138 774791 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonan acetylesterase YesY 774138..774791 Bacillus subtilis subsp. subtilis str. 168 938772 NP_388589.1 CDS yesZ NC_000964.3 774799 776790 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17056685, 17449691, 17485082; Product type e: enzyme; beta-galactosidase YesZ 774799..776790 Bacillus subtilis subsp. subtilis str. 168 936080 NP_388590.2 CDS yetA NC_000964.3 776834 779407 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 776834..779407 Bacillus subtilis subsp. subtilis str. 168 938776 NP_388591.1 CDS lplA NC_000964.3 779529 781037 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921237; Product type lp: lipoprotein; lipoprotein 779529..781037 Bacillus subtilis subsp. subtilis str. 168 936079 NP_388592.1 CDS lplB NC_000964.3 781092 782048 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter; ABC transporter permease LplB 781092..782048 Bacillus subtilis subsp. subtilis str. 168 936088 NP_388593.1 CDS lplC NC_000964.3 782062 782949 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter; ABC transporter permease LplC 782062..782949 Bacillus subtilis subsp. subtilis str. 168 938767 NP_388594.1 CDS lplD NC_000964.3 782958 784298 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; alpha-galacturonidase 782958..784298 Bacillus subtilis subsp. subtilis str. 168 938770 NP_388595.1 CDS yetF NC_000964.3 784381 785076 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 784381..785076 Bacillus subtilis subsp. subtilis str. 168 936086 NP_388596.1 CDS yetG NC_000964.3 785113 785490 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; monooxygenase complement(785113..785490) Bacillus subtilis subsp. subtilis str. 168 936085 NP_388597.1 CDS yetH NC_000964.3 785543 785905 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(785543..785905) Bacillus subtilis subsp. subtilis str. 168 938777 NP_388600.1 CDS yezD NC_000964.3 787715 787882 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 787715..787882 Bacillus subtilis subsp. subtilis str. 168 938773 NP_388601.1 CDS yetJ NC_000964.3 787992 788636 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 787992..788636 Bacillus subtilis subsp. subtilis str. 168 938782 NP_388602.1 CDS yetK NC_000964.3 788636 789628 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 788636..789628 Bacillus subtilis subsp. subtilis str. 168 936091 NP_388603.1 CDS yetL NC_000964.3 789652 790155 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator complement(789652..790155) Bacillus subtilis subsp. subtilis str. 168 938778 NP_388604.1 CDS yetM NC_000964.3 790318 791427 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 790318..791427 Bacillus subtilis subsp. subtilis str. 168 936090 NP_388605.1 CDS yetN NC_000964.3 791462 792532 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(791462..792532) Bacillus subtilis subsp. subtilis str. 168 936089 NP_388606.1 CDS yetO NC_000964.3 792682 795867 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11574077, 2544578; Product type pe: enzyme; bifunctional P-450/NADPH-P450 reductase 1 792682..795867 Bacillus subtilis subsp. subtilis str. 168 938784 NP_388607.2 CDS ltaSA NC_000964.3 796314 798233 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11544192, 15187182, 17434969, 17483484; Product type e: enzyme; lipoteichoic acid synthase 796314..798233 Bacillus subtilis subsp. subtilis str. 168 936099 NP_388608.1 CDS yfnH NC_000964.3 798469 799233 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glucose-1-phosphate cytidylyltransferase 798469..799233 Bacillus subtilis subsp. subtilis str. 168 938779 NP_388609.1 CDS yfnG NC_000964.3 799303 800208 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; CDP-sugar-dehydratase/epimerase 799303..800208 Bacillus subtilis subsp. subtilis str. 168 938783 NP_388610.1 CDS yfnF NC_000964.3 800232 801143 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 800232..801143 Bacillus subtilis subsp. subtilis str. 168 936097 NP_388611.1 CDS yfnE NC_000964.3 801172 802350 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YfnE 801172..802350 Bacillus subtilis subsp. subtilis str. 168 938781 NP_388612.1 CDS yfnD NC_000964.3 802351 803286 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 802351..803286 Bacillus subtilis subsp. subtilis str. 168 936096 NP_388613.1 CDS yfnC NC_000964.3 803317 804546 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(803317..804546) Bacillus subtilis subsp. subtilis str. 168 936104 NP_388614.1 CDS yfnB NC_000964.3 804657 805364 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; HAD-hydrolase YfnB complement(804657..805364) Bacillus subtilis subsp. subtilis str. 168 936095 NP_388615.1 CDS yfnA NC_000964.3 805456 806841 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 2541919; Product type t: transporter; amino acid permease YfnA complement(805456..806841) Bacillus subtilis subsp. subtilis str. 168 936098 NP_388616.1 CDS yfmT NC_000964.3 807091 808548 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pe : enzyme; aldehyde dehydrogenase YfmT 807091..808548 Bacillus subtilis subsp. subtilis str. 168 938788 NP_388617.1 CDS yfmS NC_000964.3 808562 809422 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pr : regulator; sensory transducer protein YfmS 808562..809422 Bacillus subtilis subsp. subtilis str. 168 936102 NP_388618.1 CDS yfmR NC_000964.3 809557 811446 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10715006, 16109936; Product type pe: enzyme; ABC transporter ATP-binding protein 809557..811446 Bacillus subtilis subsp. subtilis str. 168 936100 NP_388619.1 CDS yfmQ NC_000964.3 811569 812015 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 811569..812015 Bacillus subtilis subsp. subtilis str. 168 938786 NP_388620.1 CDS yfmP NC_000964.3 812140 812562 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator; MerR family transcriptional regulator 812140..812562 Bacillus subtilis subsp. subtilis str. 168 936101 NP_388621.1 CDS yfmO NC_000964.3 812628 813818 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075, 15849754, 16850406; Product type t: transporter; MFS transporter 812628..813818 Bacillus subtilis subsp. subtilis str. 168 936111 NP_388622.1 CDS yfmN NC_000964.3 814109 814264 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 814109..814264 Bacillus subtilis subsp. subtilis str. 168 938796 NP_388623.2 CDS yfmM NC_000964.3 814384 815940 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 16109936; Product type pt: transporter; ABC transporter ATP-binding protein complement(814384..815940) Bacillus subtilis subsp. subtilis str. 168 936103 NP_388624.1 CDS yfmL NC_000964.3 816113 817243 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11976317; Product type pe : enzyme; ATP-dependent RNA helicase YfmL 816113..817243 Bacillus subtilis subsp. subtilis str. 168 938792 NP_388625.1 CDS yfmK NC_000964.3 817311 817757 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YfmK 817311..817757 Bacillus subtilis subsp. subtilis str. 168 936108 NP_388626.1 CDS yfmJ NC_000964.3 817810 818829 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADP-dependent oxidoreductase YfmJ complement(817810..818829) Bacillus subtilis subsp. subtilis str. 168 936106 NP_388627.1 CDS yfmI NC_000964.3 819311 820531 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(819311..820531) Bacillus subtilis subsp. subtilis str. 168 936105 NP_388629.1 CDS yfmG NC_000964.3 820867 822330 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 820867..822330 Bacillus subtilis subsp. subtilis str. 168 938798 NP_388630.1 CDS yfmF NC_000964.3 822903 823703 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672620; Product type t: transporter; Fe(3+)-citrate import ATP-binding protein YfmF complement(822903..823703) Bacillus subtilis subsp. subtilis str. 168 936117 NP_388631.1 CDS yfmE NC_000964.3 823716 824717 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16672620, 16850406; Product type t: transporter; Fe(3+)-citrate import system permease protein YfmE complement(823716..824717) Bacillus subtilis subsp. subtilis str. 168 939692 NP_388632.1 CDS yfmD NC_000964.3 824714 825715 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; Fe(3+)-citrate import system permease protein YfmD complement(824714..825715) Bacillus subtilis subsp. subtilis str. 168 936110 NP_388633.1 CDS yfmC NC_000964.3 825787 826734 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter; Fe(3+)-citrate-binding protein YfmC complement(825787..826734) Bacillus subtilis subsp. subtilis str. 168 936114 NP_388634.1 CDS yfmB NC_000964.3 826843 827211 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(826843..827211) Bacillus subtilis subsp. subtilis str. 168 938795 NP_388635.1 CDS yfmA NC_000964.3 827252 827419 D Evidence 6: Doubtful CDS; hypothetical protein 827252..827419 Bacillus subtilis subsp. subtilis str. 168 938800 NP_388636.1 CDS yflT NC_000964.3 827455 827802 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12089032; Product type f: factor; general stress protein 17M 827455..827802 Bacillus subtilis subsp. subtilis str. 168 938794 NP_388637.1 CDS pel NC_000964.3 827993 829255 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12823818, 8262178; Product type e: enzyme; pectate lyase 827993..829255 Bacillus subtilis subsp. subtilis str. 168 936113 NP_388638.1 CDS yflS NC_000964.3 829382 830818 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12949159, 15849754, 16850406; Product type t: transporter; malate transporter YflS 829382..830818 Bacillus subtilis subsp. subtilis str. 168 936122 NP_388639.1 CDS citS NC_000964.3 830945 832573 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type rc: receptor; sensor protein CitS 830945..832573 Bacillus subtilis subsp. subtilis str. 168 939687 NP_388640.1 CDS citT NC_000964.3 832545 833225 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type r: regulator; transcriptional regulatory protein CitT 832545..833225 Bacillus subtilis subsp. subtilis str. 168 938806 NP_388641.2 CDS yflP NC_000964.3 833228 834187 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 833228..834187 Bacillus subtilis subsp. subtilis str. 168 936116 NP_388642.1 CDS citM NC_000964.3 834383 835684 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12427932, 12533460, 12906362, 12949159, 15849754, 16842348, 16850406; Product type t: transporter; Mg(2+)/citrate complex secondary transporter 834383..835684 Bacillus subtilis subsp. subtilis str. 168 938801 NP_388643.1 CDS yflN NC_000964.3 835740 836534 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10972810; Product type pe : enzyme; hypothetical protein 835740..836534 Bacillus subtilis subsp. subtilis str. 168 936120 NP_388644.2 CDS nosA NC_000964.3 836653 837744 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11856757, 12220171, 16172391; Product type e: enzyme; nitric oxide synthase oxygenase 836653..837744 Bacillus subtilis subsp. subtilis str. 168 938802 NP_388645.1 CDS yflL NC_000964.3 837735 838010 R catalyzes the hydrolysis of acylphosphate; acylphosphatase complement(837735..838010) Bacillus subtilis subsp. subtilis str. 168 939684 NP_388646.1 CDS yflK NC_000964.3 838077 838742 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886751; Product type pc : carrier; hypothetical protein 838077..838742 Bacillus subtilis subsp. subtilis str. 168 936119 NP_388647.1 CDS yflJ NC_000964.3 838783 838920 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(838783..838920) Bacillus subtilis subsp. subtilis str. 168 939685 NP_388648.1 CDS yflI NC_000964.3 839077 839232 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(839077..839232) Bacillus subtilis subsp. subtilis str. 168 936118 NP_388649.1 CDS yflH NC_000964.3 839339 839653 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368; hypothetical protein complement(839339..839653) Bacillus subtilis subsp. subtilis str. 168 936129 NP_388650.1 CDS yflG NC_000964.3 839735 840484 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 2 complement(839735..840484) Bacillus subtilis subsp. subtilis str. 168 936121 NP_388651.1 CDS nagP NC_000964.3 840656 842014 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 8246840; Product type t: transporter; PTS system N-acetylglucosamine-specific EIICB component 840656..842014 Bacillus subtilis subsp. subtilis str. 168 938807 NP_388652.1 CDS yflE NC_000964.3 842047 843996 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10658653; Product type pe : enzyme; lipoteichoic acid synthase complement(842047..843996) Bacillus subtilis subsp. subtilis str. 168 939200 NP_388653.1 CDS yflD NC_000964.3 844097 844234 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 844097..844234 Bacillus subtilis subsp. subtilis str. 168 936125 NP_388655.2 CDS yflB NC_000964.3 844253 844645 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 844253..844645 Bacillus subtilis subsp. subtilis str. 168 936124 NP_388656.1 CDS yflA NC_000964.3 844770 846185 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 844770..846185 Bacillus subtilis subsp. subtilis str. 168 939686 NP_388657.1 CDS yfkT NC_000964.3 846182 847258 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component; spore germination protein YfkT complement(846182..847258) Bacillus subtilis subsp. subtilis str. 168 936135 NP_388658.1 CDS yfkS NC_000964.3 847282 847482 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(847282..847482) Bacillus subtilis subsp. subtilis str. 168 936123 NP_388659.1 CDS yfkR NC_000964.3 847498 848652 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; spore germination protein YfkR complement(847498..848652) Bacillus subtilis subsp. subtilis str. 168 936126 NP_388660.1 CDS yfkQ NC_000964.3 848633 850174 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; membrane protein complement(848633..850174) Bacillus subtilis subsp. subtilis str. 168 939688 NP_388661.1 CDS treP NC_000964.3 850367 851779 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8755887, 8917076, 8969503; Product type t: transporter; PTS system trehalose-specific EIIBC component 850367..851779 Bacillus subtilis subsp. subtilis str. 168 939188 NP_388662.1 CDS treA NC_000964.3 851850 853535 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651129, 7751281, 8755887, 8917076, 9701821; Product type e: enzyme; trehalose-6-phosphate hydrolase 851850..853535 Bacillus subtilis subsp. subtilis str. 168 939690 NP_388663.1 CDS treR NC_000964.3 853556 854272 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8755887, 9829827; Product type r: regulator; trehalose operon transcriptional repressor 853556..854272 Bacillus subtilis subsp. subtilis str. 168 936133 NP_388664.1 CDS yfkO NC_000964.3 854412 855077 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme; NAD(P)H nitroreductase YfkO 854412..855077 Bacillus subtilis subsp. subtilis str. 168 939189 NP_388665.1 CDS yfkN NC_000964.3 855114 859502 R in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; nucleotide phosphoesterase complement(855114..859502) Bacillus subtilis subsp. subtilis str. 168 936131 NP_388666.1 CDS yfkM NC_000964.3 859745 860263 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 12354229, 16181642, 17257049, 17933887; Product type f: factor; general stress protein 18 859745..860263 Bacillus subtilis subsp. subtilis str. 168 938808 NP_388667.1 CDS yfkL NC_000964.3 860303 861493 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16828913, 16850406; Product type t : transporter; MFS transporter complement(860303..861493) Bacillus subtilis subsp. subtilis str. 168 939689 NP_388668.1 CDS yfkK NC_000964.3 861586 861801 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(861586..861801) Bacillus subtilis subsp. subtilis str. 168 936130 NP_388669.1 CDS yfkJ NC_000964.3 862004 862474 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme; low molecular weight protein-tyrosine-phosphatase YfkJ 862004..862474 Bacillus subtilis subsp. subtilis str. 168 939191 NP_388670.1 CDS yfkI NC_000964.3 862492 862812 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210; hypothetical protein 862492..862812 Bacillus subtilis subsp. subtilis str. 168 939691 NP_388671.1 CDS yfkH NC_000964.3 862836 863663 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222749, 12794188, 15849754, 16850406; Product type pe: enzyme; ribonuclease-like protein YfkH 862836..863663 Bacillus subtilis subsp. subtilis str. 168 936134 NP_388672.1 CDS yfkF NC_000964.3 863862 865037 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(863862..865037) Bacillus subtilis subsp. subtilis str. 168 939190 NP_388673.1 CDS yfkE NC_000964.3 865205 866260 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; cation exchanger YfkE 865205..866260 Bacillus subtilis subsp. subtilis str. 168 939693 NP_388674.1 CDS yfkD NC_000964.3 866331 867125 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 866331..867125 Bacillus subtilis subsp. subtilis str. 168 936138 NP_388675.1 CDS yfkC NC_000964.3 867164 868006 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; MscS family protein YfkC complement(867164..868006) Bacillus subtilis subsp. subtilis str. 168 936137 NP_388677.2 CDS yfkA NC_000964.3 868007 869128 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; radical SAM protein YfkA complement(868007..869128) Bacillus subtilis subsp. subtilis str. 168 938812 NP_388678.1 CDS yfjT NC_000964.3 869273 869458 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 869273..869458 Bacillus subtilis subsp. subtilis str. 168 939694 NP_388679.1 CDS pdaA NC_000964.3 869559 870350 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15687192; Product type e: enzyme; polysaccharide deacetylase PdaA 869559..870350 Bacillus subtilis subsp. subtilis str. 168 936136 NP_388680.2 CDS yfjR NC_000964.3 870388 871248 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(870388..871248) Bacillus subtilis subsp. subtilis str. 168 939198 NP_388681.1 CDS yfjQ NC_000964.3 871347 872306 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter; metal ion transporter YfjQ complement(871347..872306) Bacillus subtilis subsp. subtilis str. 168 936159 NP_388682.1 CDS yfjP NC_000964.3 872425 873288 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA-3-methyladenine glycosylase YfjP 872425..873288 Bacillus subtilis subsp. subtilis str. 168 939192 NP_388683.1 CDS yfjO NC_000964.3 873402 874802 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA methyltransferase YfjO 873402..874802 Bacillus subtilis subsp. subtilis str. 168 936146 YP_003097694.1 CDS yfzA NC_000964.3 875428 875694 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 875428..875694 Bacillus subtilis subsp. subtilis str. 168 8302973 NP_388684.1 CDS dusC NC_000964.3 876426 877403 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710; Product type e: enzyme; tRNA-dihydrouridine synthase 2 876426..877403 Bacillus subtilis subsp. subtilis str. 168 936154 NP_388685.1 CDS yfjM NC_000964.3 877599 878051 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 877599..878051 Bacillus subtilis subsp. subtilis str. 168 939698 NP_388686.1 CDS yfjL NC_000964.3 878081 878770 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 878081..878770 Bacillus subtilis subsp. subtilis str. 168 939202 NP_388687.1 CDS acoA NC_000964.3 879002 880003 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha 879002..880003 Bacillus subtilis subsp. subtilis str. 168 936152 NP_388688.1 CDS acoB NC_000964.3 880007 881035 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta 880007..881035 Bacillus subtilis subsp. subtilis str. 168 939697 NP_388689.1 CDS acoC NC_000964.3 881049 882245 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 11274109; Product type e: enzyme; dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system 881049..882245 Bacillus subtilis subsp. subtilis str. 168 936147 NP_388690.1 CDS acoL NC_000964.3 882266 883642 D E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase 882266..883642 Bacillus subtilis subsp. subtilis str. 168 939702 NP_388691.1 CDS acoR NC_000964.3 883758 885575 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type r: regulator; acetoin dehydrogenase operon transcriptional activator AcoR 883758..885575 Bacillus subtilis subsp. subtilis str. 168 936148 NP_388692.1 CDS sspH NC_000964.3 885629 885808 D SASP H; spore coat; expressed in forespore compartment; small acid-soluble spore protein H 885629..885808 Bacillus subtilis subsp. subtilis str. 168 939208 NP_388693.1 CDS yfjF NC_000964.3 885844 886173 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein complement(885844..886173) Bacillus subtilis subsp. subtilis str. 168 939201 NP_388694.1 CDS yfjE NC_000964.3 886223 886681 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(886223..886681) Bacillus subtilis subsp. subtilis str. 168 939699 NP_388695.1 CDS yfjD NC_000964.3 886775 887332 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; lipoprotein complement(886775..887332) Bacillus subtilis subsp. subtilis str. 168 936158 NP_388696.1 CDS yfjC NC_000964.3 887364 888131 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(887364..888131) Bacillus subtilis subsp. subtilis str. 168 939231 NP_388697.1 CDS yfjB NC_000964.3 888143 889366 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(888143..889366) Bacillus subtilis subsp. subtilis str. 168 939700 NP_388698.1 CDS yfjA NC_000964.3 889372 889686 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(889372..889686) Bacillus subtilis subsp. subtilis str. 168 936160 NP_388699.1 CDS malA NC_000964.3 890022 891371 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10329789, 11489864, 15341727, 15670594, 17676871, 9765262; Product type e : enzyme; maltose-6'-phosphate glucosidase 890022..891371 Bacillus subtilis subsp. subtilis str. 168 936161 NP_388700.1 CDS malR NC_000964.3 891436 892200 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489864; Product type r: regulator; RpiR family transcriptional regulator 891436..892200 Bacillus subtilis subsp. subtilis str. 168 939205 NP_388701.1 CDS malP NC_000964.3 892215 893798 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; PTS maltose transporter subunit IIBC 892215..893798 Bacillus subtilis subsp. subtilis str. 168 939713 NP_388702.1 CDS malQ NC_000964.3 893904 895625 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter; ABC transporter ATP-binding protein 893904..895625 Bacillus subtilis subsp. subtilis str. 168 936163 NP_388703.1 CDS yfiC NC_000964.3 895619 897433 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 895619..897433 Bacillus subtilis subsp. subtilis str. 168 936167 NP_388704.1 CDS catD NC_000964.3 897588 897992 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17407181; Product type e: enzyme; oxidoreductase 897588..897992 Bacillus subtilis subsp. subtilis str. 168 939204 NP_388705.2 CDS catE NC_000964.3 898010 898867 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17407181; Product type e: enzyme; catechol-2,3-dioxygenase 898010..898867 Bacillus subtilis subsp. subtilis str. 168 936164 NP_388706.1 CDS yfiF NC_000964.3 898961 899905 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 898961..899905 Bacillus subtilis subsp. subtilis str. 168 939704 NP_388707.1 CDS yfiG NC_000964.3 900080 901528 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transporter 900080..901528 Bacillus subtilis subsp. subtilis str. 168 939710 NP_388708.1 CDS yfiH NC_000964.3 901555 902496 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 901555..902496 Bacillus subtilis subsp. subtilis str. 168 939706 NP_388709.1 CDS yfiI NC_000964.3 902506 903687 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 902506..903687 Bacillus subtilis subsp. subtilis str. 168 936177 NP_388710.1 CDS yfiJ NC_000964.3 903811 905013 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type rc: receptor; sensor histidine kinase 903811..905013 Bacillus subtilis subsp. subtilis str. 168 936171 NP_388711.1 CDS yfiK NC_000964.3 905010 905672 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type r: regulator; transcriptional regulator 905010..905672 Bacillus subtilis subsp. subtilis str. 168 939209 NP_388712.2 CDS yfiL NC_000964.3 905816 906751 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 905816..906751 Bacillus subtilis subsp. subtilis str. 168 936175 NP_388713.1 CDS yfiM NC_000964.3 906764 907954 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YfiM 906764..907954 Bacillus subtilis subsp. subtilis str. 168 939210 NP_388714.1 CDS yfiN NC_000964.3 907968 909125 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YfiN 907968..909125 Bacillus subtilis subsp. subtilis str. 168 939705 NP_388715.1 CDS padR NC_000964.3 909198 909746 R Evidence 2b: Function of strongly homologous gene; PubMedId: 11073918, 17295427, 18326577; Product type r: regulator; negative transcription regulator PadR complement(909198..909746) Bacillus subtilis subsp. subtilis str. 168 936174 NP_388716.1 CDS estB NC_000964.3 910019 910651 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11029590, 10913700; Product type e: enzyme; extracellular esterase EstB 910019..910651 Bacillus subtilis subsp. subtilis str. 168 939715 NP_388717.1 CDS yfiQ NC_000964.3 910840 911928 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane-bound acyltransferase YfiQ 910840..911928 Bacillus subtilis subsp. subtilis str. 168 936185 NP_388718.1 CDS yfiR NC_000964.3 911964 912581 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16862575; Product type r: regulator; TetR family transcriptional regulator complement(911964..912581) Bacillus subtilis subsp. subtilis str. 168 936176 NP_388719.1 CDS yfiS NC_000964.3 912547 913800 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 16862575; Product type pt: transporter; MFS transporter complement(912547..913800) Bacillus subtilis subsp. subtilis str. 168 939219 NP_388720.1 CDS yfiT NC_000964.3 913924 914460 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15581359; Product type e: enzyme; metal-dependent hydrolase YfiT 913924..914460 Bacillus subtilis subsp. subtilis str. 168 939711 NP_388721.1 CDS yfiU NC_000964.3 914457 916013 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(914457..916013) Bacillus subtilis subsp. subtilis str. 168 936182 NP_388722.1 CDS yfiV NC_000964.3 916124 916606 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator complement(916124..916606) Bacillus subtilis subsp. subtilis str. 168 939218 YP_003097695.1 CDS mprF NC_000964.3 916778 919348 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14702396, 15849754, 16299297, 16850406, 17042784, 2490162; Product type f: factor; phosphatidylglycerol lysyltransferase 916778..919348 Bacillus subtilis subsp. subtilis str. 168 8303094 NP_388725.1 CDS yfiY NC_000964.3 919366 920343 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; siderophore-binding lipoprotein YfiY complement(919366..920343) Bacillus subtilis subsp. subtilis str. 168 939206 NP_388726.1 CDS yfiZ NC_000964.3 920474 921475 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; siderophore transport system permease protein YfiZ 920474..921475 Bacillus subtilis subsp. subtilis str. 168 936179 NP_388727.1 CDS yfhA NC_000964.3 921472 922503 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; siderophore transport system permease protein YfhA 921472..922503 Bacillus subtilis subsp. subtilis str. 168 939714 NP_388728.1 CDS yfhB NC_000964.3 922618 923499 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isomerase 922618..923499 Bacillus subtilis subsp. subtilis str. 168 936191 NP_388729.1 CDS yfhC NC_000964.3 923587 924171 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme; NAD(P)H nitroreductase YfhC 923587..924171 Bacillus subtilis subsp. subtilis str. 168 939221 NP_388730.1 CDS yfhD NC_000964.3 924210 924401 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(924210..924401) Bacillus subtilis subsp. subtilis str. 168 939709 NP_388731.1 CDS yfhE NC_000964.3 924468 924578 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(924468..924578) Bacillus subtilis subsp. subtilis str. 168 936184 NP_388732.1 CDS yfhF NC_000964.3 924633 925544 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; epimerase family protein YfhF complement(924633..925544) Bacillus subtilis subsp. subtilis str. 168 939217 NP_388733.1 CDS recX NC_000964.3 925633 926427 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; regulatory protein RecX 925633..926427 Bacillus subtilis subsp. subtilis str. 168 939727 NP_388734.1 CDS yfhH NC_000964.3 926429 926743 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 926429..926743 Bacillus subtilis subsp. subtilis str. 168 936189 NP_388735.1 CDS yfhI NC_000964.3 926886 928079 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 926886..928079 Bacillus subtilis subsp. subtilis str. 168 939712 YP_054573.1 CDS sspK NC_000964.3 928112 928264 R SASP K; found in the forespore compartment; small acid-soluble spore protein K complement(928112..928264) Bacillus subtilis subsp. subtilis str. 168 2914224 NP_388736.1 CDS yfhJ NC_000964.3 928389 928658 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 928389..928658 Bacillus subtilis subsp. subtilis str. 168 936188 NP_388737.1 CDS yfhK NC_000964.3 928803 929321 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 928803..929321 Bacillus subtilis subsp. subtilis str. 168 939215 NP_388738.1 CDS yfhL NC_000964.3 929406 929738 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16629676; Product type f: factor; hypothetical protein 929406..929738 Bacillus subtilis subsp. subtilis str. 168 939228 NP_388739.1 CDS yfhM NC_000964.3 929725 930585 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YfhM 929725..930585 Bacillus subtilis subsp. subtilis str. 168 936187 NP_388740.1 CDS csbB NC_000964.3 930818 931807 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8921856, 9636707; Product type pe: enzyme; glycosyltransferase CsbB 930818..931807 Bacillus subtilis subsp. subtilis str. 168 939717 NP_388741.2 CDS yfhO NC_000964.3 931879 934464 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 931879..934464 Bacillus subtilis subsp. subtilis str. 168 936195 NP_388742.1 CDS yfhP NC_000964.3 934457 935440 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10524235, 15849754, 16850406; Product type pe: enzyme; hypothetical protein complement(934457..935440) Bacillus subtilis subsp. subtilis str. 168 936190 NP_388743.1 CDS yfhQ NC_000964.3 935656 936765 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10463184; Product type e: enzyme; A/G-specific adenine glycosylase YfhQ 935656..936765 Bacillus subtilis subsp. subtilis str. 168 939222 NP_388744.1 CDS yfhS NC_000964.3 936773 936997 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10463184; hypothetical protein complement(936773..936997) Bacillus subtilis subsp. subtilis str. 168 936193 NP_388745.1 CDS fabL NC_000964.3 937079 937831 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-[acyl-carrier-protein] reductase [NADPH] FabL 937079..937831 Bacillus subtilis subsp. subtilis str. 168 939223 NP_388746.1 CDS sspE NC_000964.3 937900 938154 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744043, 7592342, 9540829; Product type cp: cell process; small acid-soluble spore protein gamma-type 937900..938154 Bacillus subtilis subsp. subtilis str. 168 939716 NP_388747.1 CDS ygaB NC_000964.3 938243 938587 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 938243..938587 Bacillus subtilis subsp. subtilis str. 168 939220 NP_388748.3 CDS ygaC NC_000964.3 938731 939261 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 938731..939261 Bacillus subtilis subsp. subtilis str. 168 936192 NP_388749.1 CDS ygaD NC_000964.3 939322 941091 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 939322..941091 Bacillus subtilis subsp. subtilis str. 168 936200 NP_388750.1 CDS ygaE NC_000964.3 941168 942229 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein complement(941168..942229) Bacillus subtilis subsp. subtilis str. 168 939721 NP_388751.3 CDS gsaB NC_000964.3 942449 943738 R converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; glutamate-1-semialdehyde 2,1-aminomutase complement(942449..943738) Bacillus subtilis subsp. subtilis str. 168 936194 YP_054574.1 CDS ygaF NC_000964.3 943891 944364 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10644761, 11349039, 12950915; Product type pe: enzyme; peroxiredoxin YgaF 943891..944364 Bacillus subtilis subsp. subtilis str. 168 2914207 NP_388753.1 CDS perR NC_000964.3 944487 944924 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1580225, 16541078, 16925555; Product type r: regulator; peroxide operon regulator 944487..944924 Bacillus subtilis subsp. subtilis str. 168 939227 YP_054575.1 CDS ygzB NC_000964.3 944959 945312 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(944959..945312) Bacillus subtilis subsp. subtilis str. 168 2914245 NP_388755.1 CDS ygxA NC_000964.3 945520 946404 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 945520..946404 Bacillus subtilis subsp. subtilis str. 168 936198 NP_388756.2 CDS spo0M NC_000964.3 953373 954149 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9795118; Product type r : regulator; sporulation-control protein spo0M complement(953373..954149) Bacillus subtilis subsp. subtilis str. 168 939725 NP_388757.2 CDS ygzA NC_000964.3 954291 954494 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 954291..954494 Bacillus subtilis subsp. subtilis str. 168 936205 YP_003097696.1 CDS ygzC NC_000964.3 954579 954851 R Evidence 5: No homology to any previously reported sequences; spore coat protein F complement(954579..954851) Bacillus subtilis subsp. subtilis str. 168 8302962 NP_388758.2 CDS ygaJ NC_000964.3 954893 955585 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YgaJ 954893..955585 Bacillus subtilis subsp. subtilis str. 168 939241 NP_388759.2 CDS thiC NC_000964.3 955895 957667 D required for the synthesis of the hydromethylpyrimidine moiety of thiamine; phosphomethylpyrimidine synthase 955895..957667 Bacillus subtilis subsp. subtilis str. 168 939745 NP_388760.2 CDS ygaK NC_000964.3 957705 959060 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8972604; Product type pe : enzyme; FAD-linked oxidoreductase YgaK complement(957705..959060) Bacillus subtilis subsp. subtilis str. 168 939245 NP_388761.1 CDS senS NC_000964.3 959290 959508 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1479343, 16321961, 8323536; Product type r: regulator; transcriptional regulator 959290..959508 Bacillus subtilis subsp. subtilis str. 168 936207 NP_388762.2 CDS katA NC_000964.3 959535 960986 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12486061, 16535198; Product type e: enzyme; vegetative catalase complement(959535..960986) Bacillus subtilis subsp. subtilis str. 168 939240 NP_388763.3 CDS ssuB NC_000964.3 961394 962161 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type t: transporter; aliphatic sulfonates import ATP-binding protein SsuB 961394..962161 Bacillus subtilis subsp. subtilis str. 168 939730 NP_388764.1 CDS ssuA NC_000964.3 962179 963177 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type f: factor; aliphatic sulfonates-binding protein 962179..963177 Bacillus subtilis subsp. subtilis str. 168 936215 NP_388765.1 CDS ssuC NC_000964.3 963174 964004 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 15849754, 16513748, 16850406, 16885442, 9782504; Product type t : transporter; aliphatic sulfonates transport permease protein SsuC 963174..964004 Bacillus subtilis subsp. subtilis str. 168 936208 NP_388766.2 CDS ssuD NC_000964.3 964027 965157 D catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 964027..965157 Bacillus subtilis subsp. subtilis str. 168 939733 NP_388767.1 CDS ygaN NC_000964.3 965261 965797 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 965261..965797 Bacillus subtilis subsp. subtilis str. 168 939249 NP_388768.1 CDS rpsN NC_000964.3 965909 966178 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; alternate 30S ribosomal protein S14 965909..966178 Bacillus subtilis subsp. subtilis str. 168 936213 NP_388769.1 CDS ygaO NC_000964.3 966196 966669 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; lipoprotein complement(966196..966669) Bacillus subtilis subsp. subtilis str. 168 939244 YP_003097697.1 CDS ygzD NC_000964.3 966671 966871 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator complement(966671..966871) Bacillus subtilis subsp. subtilis str. 168 8303098 NP_388771.1 CDS yhzB NC_000964.3 967229 967852 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(967229..967852) Bacillus subtilis subsp. subtilis str. 168 939736 NP_388772.2 CDS yhbA NC_000964.3 967935 969095 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; epoxyqueuosine reductase 967935..969095 Bacillus subtilis subsp. subtilis str. 168 939243 NP_388773.1 CDS yhbB NC_000964.3 969162 970097 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 969162..970097 Bacillus subtilis subsp. subtilis str. 168 936223 NP_388774.2 CDS cspR NC_000964.3 970135 970617 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299; Product type pe : enzyme; tRNA (cytidine(34)-2'-O)-methyltransferase 970135..970617 Bacillus subtilis subsp. subtilis str. 168 939735 NP_388775.1 CDS yhbD NC_000964.3 970667 971383 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 970667..971383 Bacillus subtilis subsp. subtilis str. 168 936214 NP_388776.1 CDS yhbE NC_000964.3 971374 972087 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 971374..972087 Bacillus subtilis subsp. subtilis str. 168 939252 NP_388777.2 CDS yhbF NC_000964.3 972099 972806 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 972099..972806 Bacillus subtilis subsp. subtilis str. 168 936219 NP_388778.1 CDS prkA NC_000964.3 973156 975051 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 8626065; Product type e: enzyme; serine protein kinase PrkA 973156..975051 Bacillus subtilis subsp. subtilis str. 168 939250 NP_388779.1 CDS yhbH NC_000964.3 975231 976409 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11988534, 12662922, 14523133; Product type f: factor; stress response UPF0229 protein YhbH 975231..976409 Bacillus subtilis subsp. subtilis str. 168 936217 NP_388780.1 CDS yhbI NC_000964.3 976569 977033 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 976569..977033 Bacillus subtilis subsp. subtilis str. 168 939247 NP_388781.1 CDS yhbJ NC_000964.3 977069 977734 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; efflux system component YhbJ 977069..977734 Bacillus subtilis subsp. subtilis str. 168 936216 NP_388782.1 CDS yhcA NC_000964.3 977775 979373 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 977775..979373 Bacillus subtilis subsp. subtilis str. 168 936235 NP_388783.1 CDS yhcB NC_000964.3 979396 979926 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15754243; Product type pe : enzyme; hypothetical protein 979396..979926 Bacillus subtilis subsp. subtilis str. 168 939734 NP_388784.1 CDS yhcC NC_000964.3 979939 980313 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 979939..980313 Bacillus subtilis subsp. subtilis str. 168 936220 NP_388785.1 CDS yhcD NC_000964.3 980313 980468 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 980313..980468 Bacillus subtilis subsp. subtilis str. 168 939260 NP_388786.1 CDS yhcE NC_000964.3 980473 981234 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 980473..981234 Bacillus subtilis subsp. subtilis str. 168 939256 NP_388787.1 CDS yhcF NC_000964.3 981237 981602 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 981237..981602 Bacillus subtilis subsp. subtilis str. 168 936231 NP_388788.1 CDS yhcG NC_000964.3 981604 982302 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pt : transporter; spermidine/putrescine ABC transporter ATP-binding protein 981604..982302 Bacillus subtilis subsp. subtilis str. 168 939738 NP_388789.1 CDS yhcH NC_000964.3 982319 983236 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467, 7476193; Product type pt: transporter; ABC transporter ATP-binding protein 982319..983236 Bacillus subtilis subsp. subtilis str. 168 936229 NP_388790.1 CDS yhcI NC_000964.3 983229 984170 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 15870467, 16850406; Product type pt: transporter; hypothetical protein 983229..984170 Bacillus subtilis subsp. subtilis str. 168 939251 NP_388791.1 CDS cspB NC_000964.3 984262 984465 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12493834, 16352840; Product type f: factor; cold shock protein CspB complement(984262..984465) Bacillus subtilis subsp. subtilis str. 168 936224 NP_388792.2 CDS yhcJ NC_000964.3 984901 985731 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 984901..985731 Bacillus subtilis subsp. subtilis str. 168 939261 NP_388793.1 CDS dgcK NC_000964.3 985734 986813 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; diguanylate cyclase complement(985734..986813) Bacillus subtilis subsp. subtilis str. 168 936246 NP_388794.1 CDS tcyP NC_000964.3 986986 988377 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter; L-cystine uptake protein TcyP 986986..988377 Bacillus subtilis subsp. subtilis str. 168 939257 NP_388795.1 CDS yhcM NC_000964.3 988417 988872 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(988417..988872) Bacillus subtilis subsp. subtilis str. 168 939279 NP_388796.2 CDS yhcN NC_000964.3 989022 989591 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9611260; Product type lp : lipoprotein; lipoprotein 989022..989591 Bacillus subtilis subsp. subtilis str. 168 939739 NP_388797.2 CDS yhcO NC_000964.3 989712 990680 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 989712..990680 Bacillus subtilis subsp. subtilis str. 168 936243 NP_388799.1 CDS yhcQ NC_000964.3 990612 991265 R Evidence 4: Homologs of previously reported genes of unknown function; spore coat protein F complement(990612..991265) Bacillus subtilis subsp. subtilis str. 168 936236 NP_388800.1 CDS yhcR NC_000964.3 991348 995001 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15292138; Product type e: enzyme; endonuclease 991348..995001 Bacillus subtilis subsp. subtilis str. 168 936241 NP_388801.1 CDS yhcS NC_000964.3 994998 995594 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823805; Product type pe : enzyme; hypothetical protein 994998..995594 Bacillus subtilis subsp. subtilis str. 168 939748 NP_388802.2 CDS yhcT NC_000964.3 995624 996532 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9814761; Product type pe : enzyme; RNA pseudouridine synthase YhcT complement(995624..996532) Bacillus subtilis subsp. subtilis str. 168 936253 NP_388803.2 CDS yhcU NC_000964.3 996643 997038 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 996643..997038 Bacillus subtilis subsp. subtilis str. 168 936261 NP_388804.1 CDS yhcV NC_000964.3 997175 997597 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; CBS domain-containing protein YhcV 997175..997597 Bacillus subtilis subsp. subtilis str. 168 939740 NP_388805.1 CDS yhcW NC_000964.3 997724 998386 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 997724..998386 Bacillus subtilis subsp. subtilis str. 168 936244 NP_388806.2 CDS yhcX NC_000964.3 998402 999943 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase 998402..999943 Bacillus subtilis subsp. subtilis str. 168 939265 NP_388807.2 CDS yhxA NC_000964.3 1000364 1001716 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11082195; Product type pe : enzyme; aminotransferase YhxA 1000364..1001716 Bacillus subtilis subsp. subtilis str. 168 939742 NP_388808.1 CDS glpP NC_000964.3 1001744 1002322 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549; Product type r: regulator; glycerol uptake operon antiterminator regulatory protein 1001744..1002322 Bacillus subtilis subsp. subtilis str. 168 936251 NP_388809.1 CDS glpF NC_000964.3 1002501 1003325 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406; Product type t: transporter; glycerol uptake facilitator protein 1002501..1003325 Bacillus subtilis subsp. subtilis str. 168 939266 NP_388810.2 CDS glpK NC_000964.3 1003344 1004834 D Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1003344..1004834 Bacillus subtilis subsp. subtilis str. 168 939741 NP_388811.2 CDS glpD NC_000964.3 1004975 1006642 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10633102, 2127799, 8825777, 9595668; Product type e: enzyme; aerobic glycerol-3-phosphate dehydrogenase 1004975..1006642 Bacillus subtilis subsp. subtilis str. 168 936250 NP_388812.2 CDS pgcA NC_000964.3 1006774 1008519 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15640167, 17662947; Product type e: enzyme; phosphoglucomutase 1006774..1008519 Bacillus subtilis subsp. subtilis str. 168 936247 NP_388813.1 CDS yhcY NC_000964.3 1008668 1009807 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type rc: receptor; sensor histidine kinase 1008668..1009807 Bacillus subtilis subsp. subtilis str. 168 939760 NP_388814.1 CDS yhcZ NC_000964.3 1009804 1010448 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type r: regulator; transcriptional regulator 1009804..1010448 Bacillus subtilis subsp. subtilis str. 168 939750 NP_388815.1 CDS yhdA NC_000964.3 1010445 1010969 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15184374, 16816187; Product type e: enzyme; FMN-dependent NADPH-azoreductase 1010445..1010969 Bacillus subtilis subsp. subtilis str. 168 936266 NP_388816.1 CDS yhdB NC_000964.3 1010984 1011226 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1010984..1011226) Bacillus subtilis subsp. subtilis str. 168 939272 NP_388817.1 CDS yhdC NC_000964.3 1011427 1011750 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1011427..1011750 Bacillus subtilis subsp. subtilis str. 168 936252 NP_388818.2 CDS lytF NC_000964.3 1011792 1013258 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10206711, 14594841, 18761694, 18761696; Product type e: enzyme; peptidoglycan endopeptidase LytF complement(1011792..1013258) Bacillus subtilis subsp. subtilis str. 168 939271 NP_388819.1 CDS nsrR NC_000964.3 1013411 1013851 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16885456, 19006327; Product type r: regulator; Rrf2 family transcriptional regulator complement(1013411..1013851) Bacillus subtilis subsp. subtilis str. 168 939744 NP_388820.1 CDS ygxB NC_000964.3 1013958 1015616 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1013958..1015616) Bacillus subtilis subsp. subtilis str. 168 936263 NP_388821.1 CDS spoVR NC_000964.3 1015647 1017053 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 8144469; Product type ph: phenotype; stage V sporulation protein R 1015647..1017053 Bacillus subtilis subsp. subtilis str. 168 939747 NP_388822.2 CDS phoA NC_000964.3 1017083 1018468 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12897025, 8830275; Product type e: enzyme; alkaline phosphatase complement(1017083..1018468) Bacillus subtilis subsp. subtilis str. 168 936265 NP_388823.2 CDS lytE NC_000964.3 1018998 1020002 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244, 16950129, 9457885; Product type e: enzyme; peptidoglycan endopeptidase LytE 1018998..1020002 Bacillus subtilis subsp. subtilis str. 168 939269 NP_388824.2 CDS citR NC_000964.3 1020073 1020948 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8045899; Product type r : regulator; LysR family transcriptional regulator complement(1020073..1020948) Bacillus subtilis subsp. subtilis str. 168 939267 NP_388825.2 CDS citA NC_000964.3 1021057 1022157 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 4211224, 8045898, 8045899; Product type e: enzyme; citrate synthase 1021057..1022157 Bacillus subtilis subsp. subtilis str. 168 936270 NP_388826.1 CDS yhdF NC_000964.3 1022231 1023100 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; oxidoreductase 1022231..1023100 Bacillus subtilis subsp. subtilis str. 168 939749 NP_388827.1 CDS ctrA NC_000964.3 1023350 1024747 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16621821, 16850406; Product type t : transporter; amino acid permease 1023350..1024747 Bacillus subtilis subsp. subtilis str. 168 939746 NP_388828.1 CDS yhdH NC_000964.3 1024865 1026220 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YhdH 1024865..1026220 Bacillus subtilis subsp. subtilis str. 168 936264 NP_388829.1 CDS yhdI NC_000964.3 1026255 1027664 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator complement(1026255..1027664) Bacillus subtilis subsp. subtilis str. 168 939277 NP_388830.1 CDS yhdJ NC_000964.3 1027774 1028202 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; N-acetyltransferase YhdJ 1027774..1028202 Bacillus subtilis subsp. subtilis str. 168 939275 NP_388831.1 CDS yhdK NC_000964.3 1028233 1028523 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype; anti-sigma-M factor YhdK complement(1028233..1028523) Bacillus subtilis subsp. subtilis str. 168 936268 NP_388832.1 CDS yhdL NC_000964.3 1028511 1029587 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype; anti-sigma-M factor YhdL complement(1028511..1029587) Bacillus subtilis subsp. subtilis str. 168 939753 NP_388833.1 CDS sigM NC_000964.3 1029577 1030068 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress; RNA polymerase sigma factor SigM complement(1029577..1030068) Bacillus subtilis subsp. subtilis str. 168 936267 NP_388834.1 CDS yhdN NC_000964.3 1030265 1031260 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 15019785; Product type e: enzyme; general stress protein 69 1030265..1031260 Bacillus subtilis subsp. subtilis str. 168 939270 NP_388835.1 CDS plsC NC_000964.3 1031395 1031994 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 1557036, 17557823; Product type e: enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1031395..1031994 Bacillus subtilis subsp. subtilis str. 168 936269 NP_388836.1 CDS yhdP NC_000964.3 1032063 1033397 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pt : transporter; hypothetical protein complement(1032063..1033397) Bacillus subtilis subsp. subtilis str. 168 939280 NP_388837.1 CDS cueR NC_000964.3 1033458 1033889 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator; MerR family transcriptional regulator complement(1033458..1033889) Bacillus subtilis subsp. subtilis str. 168 939283 NP_388838.1 CDS yhdR NC_000964.3 1034046 1035227 D catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1034046..1035227 Bacillus subtilis subsp. subtilis str. 168 939752 NP_388840.1 CDS yhdT NC_000964.3 1035554 1036939 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 1035554..1036939 Bacillus subtilis subsp. subtilis str. 168 936275 NP_388841.1 CDS crcBA NC_000964.3 1036953 1037309 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; protein CrcB homolog 1 complement(1036953..1037309) Bacillus subtilis subsp. subtilis str. 168 939754 NP_388842.1 CDS yhdV NC_000964.3 1037306 1037701 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12904550, 15849754, 16850406, 8844142; Product type f: factor; protein CrcB homolog 2 complement(1037306..1037701) Bacillus subtilis subsp. subtilis str. 168 936272 NP_388843.1 CDS yhdW NC_000964.3 1037688 1038419 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8012593; Product type pe : enzyme; glycerophosphoryl diester phosphodiesterase complement(1037688..1038419) Bacillus subtilis subsp. subtilis str. 168 939751 NP_388844.1 CDS yhdX NC_000964.3 1038653 1038760 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1038653..1038760 Bacillus subtilis subsp. subtilis str. 168 939284 NP_388845.1 CDS yhdY NC_000964.3 1038909 1040024 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12077558, 15849754, 16850406; Product type pm: membrane component; small mechanosensitive ion chanel protein MscS 1038909..1040024 Bacillus subtilis subsp. subtilis str. 168 939285 NP_388846.1 CDS yhdZ NC_000964.3 1040094 1040837 D Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent protein deacetylase 1040094..1040837 Bacillus subtilis subsp. subtilis str. 168 936271 NP_388847.1 CDS yheN NC_000964.3 1040861 1041709 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polysaccharide deacetylase complement(1040861..1041709) Bacillus subtilis subsp. subtilis str. 168 936280 NP_388848.1 CDS dat NC_000964.3 1041994 1042842 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17005988, 9003455; Product type e: enzyme; D-alanine aminotransferase 1041994..1042842 Bacillus subtilis subsp. subtilis str. 168 939759 NP_388849.1 CDS nhaC NC_000964.3 1042885 1044246 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 11274110, 15849754, 16850406; Product type t: transporter; Na(+)/H(+) antiporter NhaC complement(1042885..1044246) Bacillus subtilis subsp. subtilis str. 168 936274 NP_388850.2 CDS nhaX NC_000964.3 1044373 1044873 R Evidence 2b: Function of strongly homologous gene; PubMedId: 1198853, 16159758; Product type f : factor; stress response protein NhaX complement(1044373..1044873) Bacillus subtilis subsp. subtilis str. 168 939286 NP_388851.1 CDS yheJ NC_000964.3 1045037 1045198 D Evidence 6: Doubtful CDS; hypothetical protein 1045037..1045198 Bacillus subtilis subsp. subtilis str. 168 939757 NP_388852.1 CDS yheI NC_000964.3 1045318 1047075 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein YheI 1045318..1047075 Bacillus subtilis subsp. subtilis str. 168 936278 NP_388853.1 CDS yheH NC_000964.3 1047072 1049093 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein YheH 1047072..1049093 Bacillus subtilis subsp. subtilis str. 168 939287 NP_388854.1 CDS yheG NC_000964.3 1049142 1049762 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(1049142..1049762) Bacillus subtilis subsp. subtilis str. 168 939755 NP_388855.1 CDS yheF NC_000964.3 1049801 1049926 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1049801..1049926) Bacillus subtilis subsp. subtilis str. 168 936277 NP_388856.1 CDS sspB NC_000964.3 1050031 1050234 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 3009398, 9572981; Product type cp: cell process; small acid-soluble spore protein B complement(1050031..1050234) Bacillus subtilis subsp. subtilis str. 168 939281 NP_388857.1 CDS yheE NC_000964.3 1050443 1050661 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1050443..1050661) Bacillus subtilis subsp. subtilis str. 168 939756 NP_388858.2 CDS yheD NC_000964.3 1050811 1052172 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type f: factor; endospore coat-associated protein YheD complement(1050811..1052172) Bacillus subtilis subsp. subtilis str. 168 936276 NP_388859.1 CDS yheC NC_000964.3 1052162 1053253 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15231775; Product type f: factor; endospore coat-associated protein YheC complement(1052162..1053253) Bacillus subtilis subsp. subtilis str. 168 939293 NP_388860.1 CDS yheB NC_000964.3 1053520 1054653 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16684363; hypothetical protein 1053520..1054653 Bacillus subtilis subsp. subtilis str. 168 939764 NP_388861.1 CDS yheA NC_000964.3 1054746 1055099 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1054746..1055099 Bacillus subtilis subsp. subtilis str. 168 936288 NP_388862.1 CDS yhaZ NC_000964.3 1055143 1056216 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290; hypothetical protein complement(1055143..1056216) Bacillus subtilis subsp. subtilis str. 168 939758 NP_388864.2 CDS yhaX NC_000964.3 1056702 1057568 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pe : enzyme; hydrolase 1056702..1057568 Bacillus subtilis subsp. subtilis str. 168 939288 NP_388865.1 CDS hemZ NC_000964.3 1057680 1059185 D catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; oxygen-independent coproporphyrinogen-III oxidase 1057680..1059185 Bacillus subtilis subsp. subtilis str. 168 937935 NP_388866.2 CDS yhaU NC_000964.3 1059203 1060420 R Evidence 2b: Function of strongly homologous gene; PubMedId: 14987767, 15849754, 15919996, 16850406; Product type t: transporter; K(+)/H(+) antiporter YhaU complement(1059203..1060420) Bacillus subtilis subsp. subtilis str. 168 939761 NP_388867.1 CDS khtT NC_000964.3 1060427 1060924 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type t: transporter; K(+)/H(+) antiporter subunit KhtT complement(1060427..1060924) Bacillus subtilis subsp. subtilis str. 168 936284 NP_388868.1 CDS khtS NC_000964.3 1060988 1061326 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type f: factor; hypothetical protein complement(1060988..1061326) Bacillus subtilis subsp. subtilis str. 168 939291 NP_388869.3 CDS yhaR NC_000964.3 1061491 1062258 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase/isomerase YhaR 1061491..1062258 Bacillus subtilis subsp. subtilis str. 168 939767 YP_003097698.1 CDS yhzD NC_000964.3 1062279 1062464 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1062279..1062464) Bacillus subtilis subsp. subtilis str. 168 8303023 NP_388870.2 CDS natA NC_000964.3 1062591 1063487 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 9106203; Product type t: transporter; ABC transporter ATP-binding protein 1062591..1063487 Bacillus subtilis subsp. subtilis str. 168 936283 NP_388871.2 CDS natB NC_000964.3 1063480 1064739 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 9106203; Product type t: transporter; hypothetical protein 1063480..1064739 Bacillus subtilis subsp. subtilis str. 168 939763 NP_388872.1 CDS yhaO NC_000964.3 1064846 1066072 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; metallophosphoesterase 1064846..1066072 Bacillus subtilis subsp. subtilis str. 168 936282 NP_388873.1 CDS yhaN NC_000964.3 1066077 1068968 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 1066077..1068968 Bacillus subtilis subsp. subtilis str. 168 936294 NP_388874.1 CDS yhaM NC_000964.3 1069042 1069986 D catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates; 3'-5' exoribonuclease YhaM 1069042..1069986 Bacillus subtilis subsp. subtilis str. 168 939762 NP_388875.1 CDS yhaL NC_000964.3 1070111 1070323 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523133; Product type ph: phenotype; sporulation protein YhaL 1070111..1070323 Bacillus subtilis subsp. subtilis str. 168 936285 NP_388876.1 CDS prsA NC_000964.3 1070364 1071242 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12634326, 12682299, 14976191, 16516208; Product type lp: lipoprotein; foldase protein PrsA complement(1070364..1071242) Bacillus subtilis subsp. subtilis str. 168 939294 YP_003097699.1 CDS yhzE NC_000964.3 1071402 1071488 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1071402..1071488 Bacillus subtilis subsp. subtilis str. 168 8303205 NP_388878.2 CDS yhaJ NC_000964.3 1072042 1072560 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; membrane protein complement(1072042..1072560) Bacillus subtilis subsp. subtilis str. 168 936292 NP_388879.1 CDS yhaI NC_000964.3 1072768 1073109 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1072768..1073109 Bacillus subtilis subsp. subtilis str. 168 939295 NP_388880.1 CDS hpr NC_000964.3 1073106 1073717 R hpr; ScoC; MarR family; protease production regulatory protein; MarR family transcriptional regulator complement(1073106..1073717) Bacillus subtilis subsp. subtilis str. 168 939765 NP_388881.1 CDS yhaH NC_000964.3 1073895 1074251 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11429463; Product type pm : membrane component; membrane protein complement(1073895..1074251) Bacillus subtilis subsp. subtilis str. 168 936291 YP_003097700.1 CDS yhzF NC_000964.3 1074381 1074572 D Evidence 5: No homology to any previously reported sequences; membrane protein 1074381..1074572 Bacillus subtilis subsp. subtilis str. 168 8303073 NP_388882.2 CDS trpP NC_000964.3 1074646 1075164 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702295, 15849754, 16850406, 10735881; Product type t: transporter; tryptophan transport protein complement(1074646..1075164) Bacillus subtilis subsp. subtilis str. 168 936290 NP_388883.1 CDS serC NC_000964.3 1075289 1076368 R catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase complement(1075289..1076368) Bacillus subtilis subsp. subtilis str. 168 936304 NP_388884.1 CDS hinT NC_000964.3 1076515 1076952 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15703176, 16934294, 9579061; Product type e : enzyme; protein hit complement(1076515..1076952) Bacillus subtilis subsp. subtilis str. 168 939769 NP_388885.1 CDS ecsA NC_000964.3 1077440 1078183 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 11807061, 8581172; Product type t: transporter; ABC transporter ATP-binding protein 1077440..1078183 Bacillus subtilis subsp. subtilis str. 168 936293 NP_388886.1 CDS ecsB NC_000964.3 1078176 1079402 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 15175311, 15849754, 16850406, 8581172; Product type t : transporter; ABC transporter permease EcsB 1078176..1079402 Bacillus subtilis subsp. subtilis str. 168 939298 NP_388887.1 CDS ecsC NC_000964.3 1079422 1080132 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10027970; Product type pe : enzyme; ABC transporter substrate-binding protein EcsC 1079422..1080132 Bacillus subtilis subsp. subtilis str. 168 939774 NP_388888.2 CDS yhaA NC_000964.3 1080150 1081340 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amidohydrolase YhaA complement(1080150..1081340) Bacillus subtilis subsp. subtilis str. 168 936299 NP_388889.1 CDS yhfA NC_000964.3 1081413 1082804 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein complement(1081413..1082804) Bacillus subtilis subsp. subtilis str. 168 939301 NP_388890.1 CDS yhgB NC_000964.3 1082870 1083184 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1082870..1083184) Bacillus subtilis subsp. subtilis str. 168 936298 NP_388891.1 CDS yhgC NC_000964.3 1083229 1083729 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1083229..1083729) Bacillus subtilis subsp. subtilis str. 168 939297 NP_388892.2 CDS pbpF NC_000964.3 1083851 1085995 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11567005, 8335642; Product type e: enzyme; penicillin-binding protein 1F 1083851..1085995 Bacillus subtilis subsp. subtilis str. 168 939766 NP_388893.1 CDS hemE NC_000964.3 1086117 1087178 D catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1086117..1087178 Bacillus subtilis subsp. subtilis str. 168 936296 NP_388894.1 CDS hemH NC_000964.3 1087250 1088182 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1087250..1088182 Bacillus subtilis subsp. subtilis str. 168 939772 NP_388895.1 CDS hemY NC_000964.3 1088197 1089609 D catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1088197..1089609 Bacillus subtilis subsp. subtilis str. 168 936311 NP_388896.1 CDS yhgD NC_000964.3 1089755 1090330 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator; TetR family transcriptional regulator 1089755..1090330 Bacillus subtilis subsp. subtilis str. 168 939305 NP_388897.1 CDS yhgE NC_000964.3 1090401 1092728 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor; hypothetical protein 1090401..1092728 Bacillus subtilis subsp. subtilis str. 168 936303 NP_388898.1 CDS fabHB NC_000964.3 1092770 1093747 R FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 complement(1092770..1093747) Bacillus subtilis subsp. subtilis str. 168 939306 NP_388899.1 CDS yhfC NC_000964.3 1093874 1094650 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1093874..1094650 Bacillus subtilis subsp. subtilis str. 168 936308 NP_388901.1 CDS yhfE NC_000964.3 1095063 1096103 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase YhfE 1095063..1096103 Bacillus subtilis subsp. subtilis str. 168 936306 NP_388902.1 CDS yhfF NC_000964.3 1096116 1096523 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1096116..1096523 Bacillus subtilis subsp. subtilis str. 168 939309 NP_388903.1 CDS gltT NC_000964.3 1096560 1097849 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8634258; Product type t : transporter; proton/sodium-glutamate symport protein complement(1096560..1097849) Bacillus subtilis subsp. subtilis str. 168 939770 NP_388904.1 CDS yhfH NC_000964.3 1098120 1098260 R Evidence 6: Doubtful CDS; hypothetical protein complement(1098120..1098260) Bacillus subtilis subsp. subtilis str. 168 936305 NP_388905.1 CDS yhfI NC_000964.3 1098412 1099146 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1098412..1099146 Bacillus subtilis subsp. subtilis str. 168 936318 NP_388906.1 CDS yhfJ NC_000964.3 1099159 1100154 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoate-protein ligase LplJ 1099159..1100154 Bacillus subtilis subsp. subtilis str. 168 939310 NP_388907.1 CDS yhfK NC_000964.3 1100219 1100863 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11790741; Product type pe : enzyme; sugar epimerase YhfK 1100219..1100863 Bacillus subtilis subsp. subtilis str. 168 936309 NP_388908.2 CDS yhfL NC_000964.3 1100980 1102521 D activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1100980..1102521 Bacillus subtilis subsp. subtilis str. 168 939308 NP_388909.1 CDS yhfM NC_000964.3 1102560 1102955 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1102560..1102955) Bacillus subtilis subsp. subtilis str. 168 936312 NP_388910.1 CDS yhfN NC_000964.3 1103104 1104384 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9015299; Product type pe : enzyme; metalloprotease YhfN 1103104..1104384 Bacillus subtilis subsp. subtilis str. 168 936314 NP_388911.2 CDS aprE NC_000964.3 1104423 1105568 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 14688235, 15205417, 17666034, 3108260, 9811547; Product type e : enzyme; subtilisin E complement(1104423..1105568) Bacillus subtilis subsp. subtilis str. 168 939313 NP_388912.1 CDS yhfO NC_000964.3 1106003 1106452 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YhfO 1106003..1106452 Bacillus subtilis subsp. subtilis str. 168 939778 NP_388913.1 CDS yhfP NC_000964.3 1106524 1107516 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12057962, 9643546; Product type pe: enzyme; quinone oxidoreductase YhfP 1106524..1107516 Bacillus subtilis subsp. subtilis str. 168 939312 NP_388914.2 CDS yhfQ NC_000964.3 1107733 1108704 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter substrate-binding protein 1107733..1108704 Bacillus subtilis subsp. subtilis str. 168 936324 NP_388915.1 CDS phoE NC_000964.3 1108736 1109317 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10869096, 11827481, 17693564; Product type e: enzyme; phosphatase PhoE complement(1108736..1109317) Bacillus subtilis subsp. subtilis str. 168 939773 NP_388916.1 CDS yhfS NC_000964.3 1109388 1110482 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(1109388..1110482) Bacillus subtilis subsp. subtilis str. 168 939311 NP_388917.1 CDS yhfT NC_000964.3 1110479 1111918 R activates fatty acids by binding to coenzyme A; acyl--CoA ligase complement(1110479..1111918) Bacillus subtilis subsp. subtilis str. 168 936315 NP_388918.1 CDS bioY NC_000964.3 1111925 1112485 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12368242, 15849754, 16850406; Product type t: transporter; biotin transporter BioY complement(1111925..1112485) Bacillus subtilis subsp. subtilis str. 168 939321 NP_388919.1 CDS hemAT NC_000964.3 1112620 1113918 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11481493, 12657801, 12962628, 15033535, 16819829, 17003124; Product type rc : receptor; heme-based aerotactic transducer HemAT complement(1112620..1113918) Bacillus subtilis subsp. subtilis str. 168 936320 NP_388920.1 CDS yhfW NC_000964.3 1114057 1115586 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; rieske 2Fe-2S iron-sulfur protein YhfW complement(1114057..1115586) Bacillus subtilis subsp. subtilis str. 168 936319 NP_388921.1 CDS yhxC NC_000964.3 1115698 1116555 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1115698..1116555 Bacillus subtilis subsp. subtilis str. 168 939316 NP_388922.1 CDS yhzC NC_000964.3 1116583 1116816 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1116583..1116816) Bacillus subtilis subsp. subtilis str. 168 939319 NP_388923.1 CDS comK NC_000964.3 1117109 1117687 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619, 16554821, 16907804, 17468244; Product type r: regulator; competence transcription factor 1117109..1117687 Bacillus subtilis subsp. subtilis str. 168 936338 NP_388924.1 CDS yhxD NC_000964.3 1117734 1118633 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(1117734..1118633) Bacillus subtilis subsp. subtilis str. 168 939776 NP_388925.1 CDS yhjA NC_000964.3 1118850 1119119 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1118850..1119119 Bacillus subtilis subsp. subtilis str. 168 936321 NP_388926.1 CDS yhjB NC_000964.3 1119162 1120631 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16267290, 16850406; Product type pt: transporter; symporter complement(1119162..1120631) Bacillus subtilis subsp. subtilis str. 168 939317 NP_388927.1 CDS yhjC NC_000964.3 1120628 1120828 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pf : factor; membrane protein complement(1120628..1120828) Bacillus subtilis subsp. subtilis str. 168 939777 NP_388928.1 CDS yhjD NC_000964.3 1121036 1121398 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290; hypothetical protein complement(1121036..1121398) Bacillus subtilis subsp. subtilis str. 168 936334 NP_388929.1 CDS yhjE NC_000964.3 1121550 1122173 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1121550..1122173 Bacillus subtilis subsp. subtilis str. 168 936333 NP_388930.1 CDS sipV NC_000964.3 1122175 1122681 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11309398, 14568161, 9325333; Product type e: enzyme; signal peptidase I V 1122175..1122681 Bacillus subtilis subsp. subtilis str. 168 939318 NP_388931.1 CDS yhjG NC_000964.3 1122862 1124361 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15121720, 7678243; Product type pe: enzyme; aromatic compound monooxygenase YhjG 1122862..1124361 Bacillus subtilis subsp. subtilis str. 168 936325 NP_388932.1 CDS yhjH NC_000964.3 1124438 1124965 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 1124438..1124965 Bacillus subtilis subsp. subtilis str. 168 939329 NP_388933.1 CDS glcP NC_000964.3 1125123 1126328 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17056753; Product type t: transporter; sugar transporter complement(1125123..1126328) Bacillus subtilis subsp. subtilis str. 168 936346 NP_388934.2 CDS ntdC NC_000964.3 1126400 1127452 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon putative oxidoreductase NtdC complement(1126400..1127452) Bacillus subtilis subsp. subtilis str. 168 936337 NP_388935.2 CDS ntdB NC_000964.3 1127466 1128314 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon putative hydrolase NtdB complement(1127466..1128314) Bacillus subtilis subsp. subtilis str. 168 939323 NP_388936.1 CDS ntdA NC_000964.3 1128286 1129611 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon protein NtdA complement(1128286..1129611) Bacillus subtilis subsp. subtilis str. 168 939788 NP_388937.1 CDS yhjM NC_000964.3 1129715 1130704 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056753; Product type r: regulator; NTD biosynthesis operon regulator NtdR 1129715..1130704 Bacillus subtilis subsp. subtilis str. 168 936344 NP_388938.1 CDS yhjN NC_000964.3 1130918 1132072 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1130918..1132072) Bacillus subtilis subsp. subtilis str. 168 939324 NP_388939.1 CDS yhjO NC_000964.3 1132179 1133384 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(1132179..1133384) Bacillus subtilis subsp. subtilis str. 168 939780 NP_388940.1 CDS yhjP NC_000964.3 1133498 1135225 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1133498..1135225 Bacillus subtilis subsp. subtilis str. 168 936342 NP_388941.1 CDS yhjQ NC_000964.3 1135255 1135581 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier; cysteine-rich protein YhjQ complement(1135255..1135581) Bacillus subtilis subsp. subtilis str. 168 939779 NP_388942.1 CDS yhjR NC_000964.3 1135699 1136136 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier; hypothetical protein complement(1135699..1136136) Bacillus subtilis subsp. subtilis str. 168 939352 NP_388943.2 CDS addB NC_000964.3 1136320 1139820 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme; ATP-dependent helicase/deoxyribonuclease subunit B 1136320..1139820 Bacillus subtilis subsp. subtilis str. 168 936341 NP_388944.2 CDS addA NC_000964.3 1139807 1143505 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme; ATP-dependent helicase/nuclease subunit A 1139807..1143505 Bacillus subtilis subsp. subtilis str. 168 939793 NP_388945.3 CDS sbcD NC_000964.3 1143577 1144752 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573, 7968921, 8493111; Product type e: enzyme; nuclease SbcCD subunit D 1143577..1144752 Bacillus subtilis subsp. subtilis str. 168 936351 NP_388946.2 CDS sbcC NC_000964.3 1144749 1148141 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573; Product type e: enzyme; nuclease SbcCD subunit C 1144749..1148141 Bacillus subtilis subsp. subtilis str. 168 939784 NP_388947.1 CDS yisB NC_000964.3 1148155 1148457 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16780573; Product type pe : enzyme; hypothetical protein 1148155..1148457 Bacillus subtilis subsp. subtilis str. 168 936345 NP_388948.1 CDS gerPF NC_000964.3 1148494 1148721 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein complement(1148494..1148721) Bacillus subtilis subsp. subtilis str. 168 939326 NP_388949.1 CDS gerPE NC_000964.3 1148744 1149145 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPE complement(1148744..1149145) Bacillus subtilis subsp. subtilis str. 168 939782 NP_388950.1 CDS gerPD NC_000964.3 1149145 1149321 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPD complement(1149145..1149321) Bacillus subtilis subsp. subtilis str. 168 936349 NP_388951.1 CDS gerPC NC_000964.3 1149318 1149935 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPC complement(1149318..1149935) Bacillus subtilis subsp. subtilis str. 168 939327 NP_388952.1 CDS gerPB NC_000964.3 1149958 1150200 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein complement(1149958..1150200) Bacillus subtilis subsp. subtilis str. 168 939781 NP_388953.1 CDS gerPA NC_000964.3 1150206 1150427 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPA complement(1150206..1150427) Bacillus subtilis subsp. subtilis str. 168 936348 NP_388954.1 CDS yisI NC_000964.3 1150850 1151020 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme; aspartyl-phosphate phosphatase YisI complement(1150850..1151020) Bacillus subtilis subsp. subtilis str. 168 936347 NP_388955.1 CDS yisJ NC_000964.3 1151166 1152089 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process; inner spore coat protein H-like protein complement(1151166..1152089) Bacillus subtilis subsp. subtilis str. 168 939786 NP_388956.1 CDS yisK NC_000964.3 1152244 1153149 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1152244..1153149 Bacillus subtilis subsp. subtilis str. 168 936356 NP_388957.1 CDS yisL NC_000964.3 1153265 1153621 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1153265..1153621 Bacillus subtilis subsp. subtilis str. 168 939333 NP_388958.1 CDS wprA NC_000964.3 1153789 1156473 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10336490, 15205417, 17269748, 9004506, 9675284; Product type e: enzyme; cell wall-associated protease 1153789..1156473 Bacillus subtilis subsp. subtilis str. 168 936350 NP_388959.1 CDS yisN NC_000964.3 1156504 1157091 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1156504..1157091) Bacillus subtilis subsp. subtilis str. 168 936354 NP_388960.2 CDS asnO NC_000964.3 1157237 1159081 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme; asparagine synthetase 3 1157237..1159081 Bacillus subtilis subsp. subtilis str. 168 939783 YP_054576.1 CDS yizA NC_000964.3 1159211 1159690 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1159211..1159690) Bacillus subtilis subsp. subtilis str. 168 2914284 NP_388961.1 CDS yisP NC_000964.3 1159922 1160746 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; squalene/phytoene synthase 1159922..1160746 Bacillus subtilis subsp. subtilis str. 168 936353 NP_388962.1 CDS yisQ NC_000964.3 1160776 1162143 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(1160776..1162143) Bacillus subtilis subsp. subtilis str. 168 939335 NP_388963.1 CDS yisR NC_000964.3 1162267 1163130 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 1162267..1163130 Bacillus subtilis subsp. subtilis str. 168 936352 NP_388964.1 CDS degA NC_000964.3 1163148 1164161 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8407808; Product type r : regulator; LacI family transcriptional regulator 1163148..1164161 Bacillus subtilis subsp. subtilis str. 168 936363 NP_388965.1 CDS yisS NC_000964.3 1164370 1165398 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pe : enzyme; oxidoreductase 1164370..1165398 Bacillus subtilis subsp. subtilis str. 168 939785 NP_388966.2 CDS yisT NC_000964.3 1165449 1165958 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1165449..1165958) Bacillus subtilis subsp. subtilis str. 168 936355 NP_388967.1 CDS yisU NC_000964.3 1166008 1166670 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid transporter YisU complement(1166008..1166670) Bacillus subtilis subsp. subtilis str. 168 939338 NP_388968.2 CDS yisV NC_000964.3 1166737 1168191 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 1166737..1168191 Bacillus subtilis subsp. subtilis str. 168 936360 NP_388970.1 CDS yisX NC_000964.3 1168199 1168837 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1168199..1168837) Bacillus subtilis subsp. subtilis str. 168 939343 NP_388971.1 CDS yisY NC_000964.3 1169043 1169849 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YisY 1169043..1169849 Bacillus subtilis subsp. subtilis str. 168 939790 NP_388972.1 CDS yisZ NC_000964.3 1169877 1170476 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme; adenylyl-sulfate kinase complement(1169877..1170476) Bacillus subtilis subsp. subtilis str. 168 936359 NP_388973.2 CDS sat NC_000964.3 1170473 1171642 R ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; sulfate adenylyltransferase complement(1170473..1171642) Bacillus subtilis subsp. subtilis str. 168 939334 NP_388974.2 CDS yitB NC_000964.3 1171755 1172465 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme; phosphoadenosine phosphosulfate reductase complement(1171755..1172465) Bacillus subtilis subsp. subtilis str. 168 939787 NP_388975.1 CDS yitC NC_000964.3 1172650 1173336 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme; 2-phosphosulfolactate phosphatase 1172650..1173336 Bacillus subtilis subsp. subtilis str. 168 936357 NP_388976.1 CDS yitD NC_000964.3 1173333 1174091 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme; phosphosulfolactate synthase 1173333..1174091 Bacillus subtilis subsp. subtilis str. 168 939794 NP_388977.1 CDS yitE NC_000964.3 1174136 1174765 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1174136..1174765) Bacillus subtilis subsp. subtilis str. 168 936377 NP_388978.1 CDS yitF NC_000964.3 1174861 1175976 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 11747447; Product type pe: enzyme; isomerase complement(1174861..1175976) Bacillus subtilis subsp. subtilis str. 168 939345 NP_388979.1 CDS yitG NC_000964.3 1175985 1177253 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15109717, 15849754, 16850406; Product type pt: transporter; MFS transporter complement(1175985..1177253) Bacillus subtilis subsp. subtilis str. 168 939791 NP_388980.1 CDS yitH NC_000964.3 1177365 1178213 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YitH complement(1177365..1178213) Bacillus subtilis subsp. subtilis str. 168 936361 NP_388981.1 CDS yitI NC_000964.3 1178218 1178682 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase complement(1178218..1178682) Bacillus subtilis subsp. subtilis str. 168 939344 NP_388982.1 CDS yitJ NC_000964.3 1178757 1180595 R catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase complement(1178757..1180595) Bacillus subtilis subsp. subtilis str. 168 939796 NP_388983.1 CDS yitK NC_000964.3 1180909 1181400 R nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; hypothetical protein complement(1180909..1181400) Bacillus subtilis subsp. subtilis str. 168 936375 NP_388984.1 CDS yitL NC_000964.3 1181499 1182395 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 1181499..1182395 Bacillus subtilis subsp. subtilis str. 168 939792 NP_388985.1 CDS yitM NC_000964.3 1182448 1183032 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1182448..1183032) Bacillus subtilis subsp. subtilis str. 168 936374 NP_388987.2 CDS yitO NC_000964.3 1183029 1183958 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1183029..1183958) Bacillus subtilis subsp. subtilis str. 168 936373 NP_388988.1 CDS yitP NC_000964.3 1183943 1184479 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 6289325; hypothetical protein complement(1183943..1184479) Bacillus subtilis subsp. subtilis str. 168 939348 YP_003097701.1 CDS yizB NC_000964.3 1184657 1185004 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein YizB 1184657..1185004 Bacillus subtilis subsp. subtilis str. 168 8302950 NP_388989.2 CDS yitQ NC_000964.3 1185001 1185588 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1185001..1185588 Bacillus subtilis subsp. subtilis str. 168 939797 NP_388990.1 CDS yitR NC_000964.3 1185608 1185901 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1185608..1185901 Bacillus subtilis subsp. subtilis str. 168 939798 NP_388991.1 CDS nprB NC_000964.3 1186037 1187653 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672610, 1917867; Product type e: enzyme; neutral protease B 1186037..1187653 Bacillus subtilis subsp. subtilis str. 168 936384 NP_388992.1 CDS yitS NC_000964.3 1187700 1188551 R Evidence 4: Homologs of previously reported genes of unknown function; Degv domain-containing protein YitS complement(1187700..1188551) Bacillus subtilis subsp. subtilis str. 168 936376 NP_388993.1 CDS yitT NC_000964.3 1188689 1189531 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1188689..1189531 Bacillus subtilis subsp. subtilis str. 168 939346 NP_388994.1 CDS ipi NC_000964.3 1189646 1190005 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226659; Product type f : factor; intracellular proteinase inhibitor 1189646..1190005 Bacillus subtilis subsp. subtilis str. 168 936380 YP_003097702.1 CDS yizC NC_000964.3 1190036 1190233 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1190036..1190233) Bacillus subtilis subsp. subtilis str. 168 8303093 NP_388995.1 CDS yitU NC_000964.3 1190490 1191302 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YitU complement(1190490..1191302) Bacillus subtilis subsp. subtilis str. 168 939795 NP_388996.1 CDS yitV NC_000964.3 1191423 1192190 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; esterase YitV 1191423..1192190 Bacillus subtilis subsp. subtilis str. 168 939350 NP_388997.1 CDS yitW NC_000964.3 1192254 1192562 D Evidence 4: Homologs of previously reported genes of unknown function; mip18 family protein YitW 1192254..1192562 Bacillus subtilis subsp. subtilis str. 168 936378 NP_388999.3 CDS yitY NC_000964.3 1192858 1194288 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16956367; Product type pe: enzyme; FAD-linked oxidoreductase YitY 1192858..1194288 Bacillus subtilis subsp. subtilis str. 168 939799 NP_389000.1 CDS yitZ NC_000964.3 1194333 1194827 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; MFS transporter 1194333..1194827 Bacillus subtilis subsp. subtilis str. 168 939355 NP_389001.2 CDS argC NC_000964.3 1195034 1196071 D catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1195034..1196071 Bacillus subtilis subsp. subtilis str. 168 936389 NP_389002.2 CDS argJ NC_000964.3 1196091 1197311 D bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; arginine biosynthesis bifunctional protein ArgJ 1196091..1197311 Bacillus subtilis subsp. subtilis str. 168 939800 NP_389003.1 CDS argB NC_000964.3 1197326 1198102 D catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1197326..1198102 Bacillus subtilis subsp. subtilis str. 168 936381 NP_389004.2 CDS argD NC_000964.3 1198099 1199256 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17012789; Product type e: enzyme; acetylornithine aminotransferase 1198099..1199256 Bacillus subtilis subsp. subtilis str. 168 939357 NP_389005.2 CDS carA NC_000964.3 1199327 1200388 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl-phosphate synthase arginine-specific small chain 1199327..1200388 Bacillus subtilis subsp. subtilis str. 168 936387 NP_389006.3 CDS carB NC_000964.3 1200381 1203473 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl-phosphate synthase arginine-specific large chain 1200381..1203473 Bacillus subtilis subsp. subtilis str. 168 939353 NP_389007.1 CDS argF NC_000964.3 1203461 1204420 D catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1203461..1204420 Bacillus subtilis subsp. subtilis str. 168 936386 NP_389008.1 CDS yjzC NC_000964.3 1204506 1204685 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1204506..1204685 Bacillus subtilis subsp. subtilis str. 168 936385 NP_389009.1 CDS yjzD NC_000964.3 1204731 1204916 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(1204731..1204916) Bacillus subtilis subsp. subtilis str. 168 939364 NP_389010.1 CDS yjaU NC_000964.3 1205165 1205899 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1205165..1205899 Bacillus subtilis subsp. subtilis str. 168 936395 NP_389011.2 CDS yjaV NC_000964.3 1205981 1206538 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type pe : enzyme; hypothetical protein 1205981..1206538 Bacillus subtilis subsp. subtilis str. 168 939802 NP_389012.2 CDS med NC_000964.3 1206629 1207582 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1203607; Product type lp: lipoprotein; transcriptional activator protein med 1206629..1207582 Bacillus subtilis subsp. subtilis str. 168 936388 NP_389013.1 CDS comZ NC_000964.3 1207597 1207788 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10940045; Product type pf : factor; ComG operon repressor 1207597..1207788 Bacillus subtilis subsp. subtilis str. 168 939358 NP_389014.1 CDS yjzB NC_000964.3 1207818 1208057 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16391061; hypothetical protein complement(1207818..1208057) Bacillus subtilis subsp. subtilis str. 168 939366 NP_389015.1 CDS fabHA NC_000964.3 1208222 1209160 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1 1208222..1209160 Bacillus subtilis subsp. subtilis str. 168 936392 NP_389016.1 CDS fabF NC_000964.3 1209183 1210424 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-[acyl-carrier-protein] synthase 2 1209183..1210424 Bacillus subtilis subsp. subtilis str. 168 939803 NP_389017.1 CDS yjaZ NC_000964.3 1210500 1211285 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1210500..1211285 Bacillus subtilis subsp. subtilis str. 168 939806 NP_389018.1 CDS appD NC_000964.3 1211477 1212463 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter; oligopeptide transport ATP-binding protein AppD 1211477..1212463 Bacillus subtilis subsp. subtilis str. 168 936391 NP_389019.2 CDS appF NC_000964.3 1212460 1213449 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter; oligopeptide transport ATP-binding protein AppF 1212460..1213449 Bacillus subtilis subsp. subtilis str. 168 936390 NP_389021.2 CDS appB NC_000964.3 1215243 1216193 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter; oligopeptide transport system permease protein AppB 1215243..1216193 Bacillus subtilis subsp. subtilis str. 168 936400 NP_389022.1 CDS appC NC_000964.3 1216210 1217121 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter; oligopeptide transport system permease protein AppC 1216210..1217121 Bacillus subtilis subsp. subtilis str. 168 936394 NP_389023.1 CDS yjbA NC_000964.3 1217326 1218078 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1217326..1218078 Bacillus subtilis subsp. subtilis str. 168 939369 NP_389024.1 CDS trpS NC_000964.3 1218113 1219105 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophan--tRNA ligase complement(1218113..1219105) Bacillus subtilis subsp. subtilis str. 168 939361 NP_389025.1 CDS oppA NC_000964.3 1219849 1221486 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11083832, 11401703, 12823818, 1901616; Product type lp: lipoprotein; oligopeptide ABC transporter binding lipoprotein 1219849..1221486 Bacillus subtilis subsp. subtilis str. 168 936398 NP_389026.1 CDS oppB NC_000964.3 1221594 1222529 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter; oligopeptide transport system permease protein OppB 1221594..1222529 Bacillus subtilis subsp. subtilis str. 168 936397 NP_389027.1 CDS oppC NC_000964.3 1222533 1223450 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter; oligopeptide transport system permease protein OppC 1222533..1223450 Bacillus subtilis subsp. subtilis str. 168 936396 NP_389028.1 CDS oppD NC_000964.3 1223455 1224531 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter; oligopeptide transport ATP-binding protein OppD 1223455..1224531 Bacillus subtilis subsp. subtilis str. 168 939814 NP_389029.1 CDS oppF NC_000964.3 1224533 1225450 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter; oligopeptide transport ATP-binding protein OppF 1224533..1225450 Bacillus subtilis subsp. subtilis str. 168 936410 NP_389030.2 CDS yjbB NC_000964.3 1225557 1226774 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 1225557..1226774 Bacillus subtilis subsp. subtilis str. 168 936399 NP_389031.2 CDS yjbC NC_000964.3 1226938 1227516 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17158660, 17158663; Product type pe: enzyme; acetyltransferase YjbC 1226938..1227516 Bacillus subtilis subsp. subtilis str. 168 939373 NP_389032.1 CDS spxA NC_000964.3 1227697 1228092 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; regulatory protein spx 1227697..1228092 Bacillus subtilis subsp. subtilis str. 168 936407 NP_389033.1 CDS yjbE NC_000964.3 1228135 1228791 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein complement(1228135..1228791) Bacillus subtilis subsp. subtilis str. 168 939805 NP_389034.1 CDS mecA NC_000964.3 1229068 1229724 D enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adapter protein MecA 1 1229068..1229724 Bacillus subtilis subsp. subtilis str. 168 936406 NP_389035.1 CDS coiA NC_000964.3 1229915 1231036 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17630974; Product type s: structure; competence protein CoiA 1229915..1231036 Bacillus subtilis subsp. subtilis str. 168 939370 NP_389036.2 CDS pepF NC_000964.3 1231083 1233095 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11741842; Product type e: enzyme; oligoendopeptidase F homolog 1231083..1233095 Bacillus subtilis subsp. subtilis str. 168 936404 YP_003097703.1 CDS yizD NC_000964.3 1233133 1233300 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(1233133..1233300) Bacillus subtilis subsp. subtilis str. 168 8303008 NP_389037.2 CDS yjbH NC_000964.3 1233614 1234513 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17293416, 17908206; Product type pe: enzyme; hypothetical protein complement(1233614..1234513) Bacillus subtilis subsp. subtilis str. 168 939365 NP_389038.1 CDS yjbI NC_000964.3 1234510 1234908 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15866723, 17293416; Product type pe: enzyme; group 2 truncated hemoglobin YjbI complement(1234510..1234908) Bacillus subtilis subsp. subtilis str. 168 936416 NP_389039.1 CDS yjbJ NC_000964.3 1235163 1235708 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; murein lytic transglycosylase YjbJ complement(1235163..1235708) Bacillus subtilis subsp. subtilis str. 168 939382 NP_389040.1 CDS yjbK NC_000964.3 1235912 1236484 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456267, 16905149, 9642185; Product type pe: enzyme; hypothetical protein complement(1235912..1236484) Bacillus subtilis subsp. subtilis str. 168 936408 NP_389041.1 CDS yjbL NC_000964.3 1236609 1236977 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1236609..1236977 Bacillus subtilis subsp. subtilis str. 168 939376 NP_389042.1 CDS yjbM NC_000964.3 1237006 1237641 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18067544; Product type e: enzyme; GTP pyrophosphokinase YjbM 1237006..1237641 Bacillus subtilis subsp. subtilis str. 168 939809 NP_389043.1 CDS ppnK NC_000964.3 1237660 1238460 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1 1237660..1238460 Bacillus subtilis subsp. subtilis str. 168 936414 NP_389044.1 CDS yjbO NC_000964.3 1238523 1239374 D Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; RNA pseudouridine synthase YjbO 1238523..1239374 Bacillus subtilis subsp. subtilis str. 168 939808 NP_389045.1 CDS yjbP NC_000964.3 1239387 1240121 R asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate; Bis(5'-nucleosyl)-tetraphosphatase PrpE complement(1239387..1240121) Bacillus subtilis subsp. subtilis str. 168 936412 NP_389046.1 CDS yjbQ NC_000964.3 1240356 1242200 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; Na(+)/H(+) antiporter YjbQ 1240356..1242200 Bacillus subtilis subsp. subtilis str. 168 939371 NP_389047.1 CDS tenA NC_000964.3 1242449 1243159 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15709744, 15858269, 16356850, 17618314, 18054064; Product type e: enzyme; thiaminase 1242449..1243159 Bacillus subtilis subsp. subtilis str. 168 939807 NP_389048.1 CDS tenI NC_000964.3 1243134 1243751 D regulates the production of extracellular enzymes; regulatory protein TenI 1243134..1243751 Bacillus subtilis subsp. subtilis str. 168 936411 NP_389049.1 CDS thiO NC_000964.3 1243735 1244844 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12627963, 15105420, 9827558; Product type e: enzyme; glycine oxidase 1243735..1244844 Bacillus subtilis subsp. subtilis str. 168 939377 NP_389050.1 CDS thiS NC_000964.3 1244844 1245044 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 14567704, 14757766, 15489164; Product type c: carrier; sulfur carrier protein ThiS 1244844..1245044 Bacillus subtilis subsp. subtilis str. 168 939811 NP_389051.1 CDS thiG NC_000964.3 1245041 1245811 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 1245041..1245811 Bacillus subtilis subsp. subtilis str. 168 936422 NP_389052.1 CDS thiF NC_000964.3 1245808 1246818 D catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; sulfur carrier protein ThiS adenylyltransferase 1245808..1246818 Bacillus subtilis subsp. subtilis str. 168 939816 NP_389053.1 CDS yjbV NC_000964.3 1246837 1247652 D catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1246837..1247652 Bacillus subtilis subsp. subtilis str. 168 936415 NP_389054.2 CDS fabI NC_000964.3 1247788 1248564 D Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1247788..1248564 Bacillus subtilis subsp. subtilis str. 168 939379 NP_389055.1 CDS cotO NC_000964.3 1248665 1249348 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process; spore coat protein O 1248665..1249348 Bacillus subtilis subsp. subtilis str. 168 939810 NP_389056.1 CDS cotZ NC_000964.3 1249442 1249888 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process; spore coat protein Z complement(1249442..1249888) Bacillus subtilis subsp. subtilis str. 168 936418 NP_389057.1 CDS cotY NC_000964.3 1250016 1250504 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766913, 7519271, 8509331; Product type cp: cell process; spore coat protein Y complement(1250016..1250504) Bacillus subtilis subsp. subtilis str. 168 939383 NP_389058.1 CDS cotX NC_000964.3 1250656 1251174 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10400595, 10788508, 12031481, 7519271, 8509331; Product type cp: cell process; spore coat protein X complement(1250656..1251174) Bacillus subtilis subsp. subtilis str. 168 936417 NP_389059.1 CDS cotW NC_000964.3 1251273 1251590 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8509331; Product type cp: cell process; spore coat protein W complement(1251273..1251590) Bacillus subtilis subsp. subtilis str. 168 939374 NP_389060.1 CDS cotV NC_000964.3 1251631 1252017 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process; spore coat protein V complement(1251631..1252017) Bacillus subtilis subsp. subtilis str. 168 939385 NP_389061.1 CDS yjcA NC_000964.3 1252177 1252533 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 15849754, 16850406; Product type cp: cell process; sporulation protein YjcA 1252177..1252533 Bacillus subtilis subsp. subtilis str. 168 936428 YP_003097704.1 CDS yjzK NC_000964.3 1252815 1253021 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1252815..1253021 Bacillus subtilis subsp. subtilis str. 168 8303173 YP_003097705.1 CDS yjcZ NC_000964.3 1253103 1253252 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523132; Product type h : extrachromosomal origin; hypothetical protein 1253103..1253252 Bacillus subtilis subsp. subtilis str. 168 8303203 NP_389063.2 CDS spoVIF NC_000964.3 1253385 1253639 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 14702409; Product type cp: cell process; sporulation-specific transcription factor SpoVIF 1253385..1253639 Bacillus subtilis subsp. subtilis str. 168 939384 NP_389064.2 CDS yjcD NC_000964.3 1253713 1255866 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544244; Product type pe : enzyme; ATP-dependent DNA helicase complement(1253713..1255866) Bacillus subtilis subsp. subtilis str. 168 939813 YP_003097706.1 CDS yjzE NC_000964.3 1256109 1256363 D Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315; hypothetical protein 1256109..1256363 Bacillus subtilis subsp. subtilis str. 168 8303175 NP_389066.1 CDS yjcF NC_000964.3 1256436 1256858 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YjcF complement(1256436..1256858) Bacillus subtilis subsp. subtilis str. 168 939387 NP_389067.1 CDS yjcG NC_000964.3 1256862 1257377 R similar to 2'-5' RNA ligase; hypothetical protein complement(1256862..1257377) Bacillus subtilis subsp. subtilis str. 168 939822 NP_389068.1 CDS yjcH NC_000964.3 1257414 1258136 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(1257414..1258136) Bacillus subtilis subsp. subtilis str. 168 936425 NP_389069.1 CDS yjcI NC_000964.3 1258492 1259613 D catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase/O-acetylhomoserine 1258492..1259613 Bacillus subtilis subsp. subtilis str. 168 939812 NP_389070.1 CDS yjcJ NC_000964.3 1259606 1260778 D catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase MetC 1259606..1260778 Bacillus subtilis subsp. subtilis str. 168 936424 NP_389071.1 CDS yjcK NC_000964.3 1260811 1261356 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2828880; Product type pe : enzyme; ribosomal-protein-alanine acetyltransferase complement(1260811..1261356) Bacillus subtilis subsp. subtilis str. 168 939406 NP_389072.1 CDS yjcL NC_000964.3 1261426 1262616 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(1261426..1262616) Bacillus subtilis subsp. subtilis str. 168 936434 NP_389073.1 CDS yjcM NC_000964.3 1263702 1264931 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1263702..1264931) Bacillus subtilis subsp. subtilis str. 168 939395 NP_389074.1 CDS yjcN NC_000964.3 1265057 1265377 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1265057..1265377 Bacillus subtilis subsp. subtilis str. 168 939817 YP_003097707.1 CDS yjzF NC_000964.3 1265530 1265661 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1265530..1265661 Bacillus subtilis subsp. subtilis str. 168 8303198 YP_003097708.1 CDS yjzG NC_000964.3 1265677 1265850 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1265677..1265850 Bacillus subtilis subsp. subtilis str. 168 8303177 NP_389075.1 CDS yjcO NC_000964.3 1265887 1266348 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 1265887..1266348 Bacillus subtilis subsp. subtilis str. 168 936430 NP_389076.1 CDS yjcP NC_000964.3 1266614 1267117 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1266614..1267117 Bacillus subtilis subsp. subtilis str. 168 936429 NP_389077.1 CDS yjcQ NC_000964.3 1267129 1267413 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1267129..1267413 Bacillus subtilis subsp. subtilis str. 168 939821 NP_389078.1 CDS yjcR NC_000964.3 1267574 1268101 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7489895, 7704261; Product type pe: enzyme; hypothetical protein 1267574..1268101 Bacillus subtilis subsp. subtilis str. 168 936443 NP_389079.1 CDS yjcS NC_000964.3 1268275 1268592 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1268275..1268592 Bacillus subtilis subsp. subtilis str. 168 939400 NP_389080.1 CDS yjdA NC_000964.3 1268829 1269584 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 1268829..1269584 Bacillus subtilis subsp. subtilis str. 168 939818 NP_389081.1 CDS yjdB NC_000964.3 1269733 1270080 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(1269733..1270080) Bacillus subtilis subsp. subtilis str. 168 936431 NP_389082.2 CDS manR NC_000964.3 1270631 1272577 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438772, 10960106; Product type r : regulator; transcriptional regulator ManR 1270631..1272577 Bacillus subtilis subsp. subtilis str. 168 939394 NP_389083.2 CDS manP NC_000964.3 1272725 1274677 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627040, 10960106; Product type t: transporter; PTS system mannose-specific EIIBCA component 1272725..1274677 Bacillus subtilis subsp. subtilis str. 168 936437 NP_389084.1 CDS manA NC_000964.3 1274692 1275639 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 7934877; Product type e: enzyme; mannose-6-phosphate isomerase ManA 1274692..1275639 Bacillus subtilis subsp. subtilis str. 168 939393 NP_389085.1 CDS yjdF NC_000964.3 1275809 1276291 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1275809..1276291 Bacillus subtilis subsp. subtilis str. 168 939820 NP_389086.1 CDS yjdG NC_000964.3 1276337 1276843 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YjdG complement(1276337..1276843) Bacillus subtilis subsp. subtilis str. 168 936436 NP_389087.2 CDS yjdH NC_000964.3 1277062 1277457 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1277062..1277457) Bacillus subtilis subsp. subtilis str. 168 939819 NP_389088.1 CDS yjdI NC_000964.3 1277686 1278165 D Evidence 4: Homologs of previously reported genes of unknown function; Cys-tRNA 1277686..1278165 Bacillus subtilis subsp. subtilis str. 168 936435 YP_003097709.1 CDS yjzH NC_000964.3 1278205 1278399 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1278205..1278399) Bacillus subtilis subsp. subtilis str. 168 8303219 NP_389089.1 CDS yjdJ NC_000964.3 1278565 1278894 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1278565..1278894) Bacillus subtilis subsp. subtilis str. 168 936449 NP_389090.2 CDS ctaO NC_000964.3 1279514 1280503 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15491161, 15849754, 16850406; Product type e: enzyme; protoheme IX farnesyltransferase complement(1279514..1280503) Bacillus subtilis subsp. subtilis str. 168 939825 NP_389091.1 CDS cotT NC_000964.3 1280626 1280949 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1391045, 1917883; Product type cp: cell process; spore coat protein complement(1280626..1280949) Bacillus subtilis subsp. subtilis str. 168 939403 NP_389092.1 CDS yjeA NC_000964.3 1281128 1282531 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 17878218; Product type e: enzyme; hypothetical protein 1281128..1282531 Bacillus subtilis subsp. subtilis str. 168 936440 NP_389093.1 CDS yjfA NC_000964.3 1282571 1283044 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1282571..1283044) Bacillus subtilis subsp. subtilis str. 168 939830 NP_389094.1 CDS yjfB NC_000964.3 1283169 1283336 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein complement(1283169..1283336) Bacillus subtilis subsp. subtilis str. 168 936446 NP_389095.2 CDS yjfC NC_000964.3 1283463 1284362 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1283463..1284362 Bacillus subtilis subsp. subtilis str. 168 939398 NP_389096.1 CDS yjgA NC_000964.3 1284371 1284769 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406; membrane protein complement(1284371..1284769) Bacillus subtilis subsp. subtilis str. 168 939397 NP_389097.1 CDS yjgB NC_000964.3 1284870 1285445 R Evidence 5: No homology to any previously reported sequences; PubMedId: 1580552; hypothetical protein complement(1284870..1285445) Bacillus subtilis subsp. subtilis str. 168 936448 NP_389098.1 CDS yjgC NC_000964.3 1285591 1288548 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1285591..1288548 Bacillus subtilis subsp. subtilis str. 168 939396 NP_389099.1 CDS yjgD NC_000964.3 1288541 1289101 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1288541..1289101 Bacillus subtilis subsp. subtilis str. 168 939826 NP_389100.1 CDS yjhA NC_000964.3 1289298 1289939 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 1289298..1289939 Bacillus subtilis subsp. subtilis str. 168 936457 NP_389101.2 CDS yjhB NC_000964.3 1290018 1290644 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12483591, 16513759; Product type pe: enzyme; ADP-ribose pyrophosphatase YjhB 1290018..1290644 Bacillus subtilis subsp. subtilis str. 168 939419 NP_389102.1 CDS yjiA NC_000964.3 1290675 1290953 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1290675..1290953) Bacillus subtilis subsp. subtilis str. 168 939399 NP_389103.1 CDS yjiB NC_000964.3 1291344 1292534 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; cytochrome P450 YjiB 1291344..1292534 Bacillus subtilis subsp. subtilis str. 168 936452 NP_389104.1 CDS yjiC NC_000964.3 1292557 1293735 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YjiC 1292557..1293735 Bacillus subtilis subsp. subtilis str. 168 939402 YP_003097710.1 CDS yjzI NC_000964.3 1293776 1293964 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1293776..1293964) Bacillus subtilis subsp. subtilis str. 168 8302936 NP_389105.1 CDS hemD NC_000964.3 1294138 1294950 D catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; hypothetical protein 1294138..1294950 Bacillus subtilis subsp. subtilis str. 168 939823 NP_389106.1 CDS yjkA NC_000964.3 1294996 1295748 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(1294996..1295748) Bacillus subtilis subsp. subtilis str. 168 936453 NP_389107.1 CDS yjkB NC_000964.3 1295748 1296500 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein complement(1295748..1296500) Bacillus subtilis subsp. subtilis str. 168 939401 NP_389108.1 CDS yjlA NC_000964.3 1296620 1297594 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(1296620..1297594) Bacillus subtilis subsp. subtilis str. 168 939404 NP_389109.1 CDS yjlB NC_000964.3 1297726 1298223 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478; hypothetical protein 1297726..1298223 Bacillus subtilis subsp. subtilis str. 168 939411 NP_389110.1 CDS rex NC_000964.3 1298612 1299034 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645; Product type r: regulator; hypothetical protein 1298612..1299034 Bacillus subtilis subsp. subtilis str. 168 939407 NP_389111.1 CDS ndh NC_000964.3 1299074 1300252 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645, 6816592; Product type e: enzyme; NADH dehydrogenase-like protein YjlD 1299074..1300252 Bacillus subtilis subsp. subtilis str. 168 939832 NP_389112.1 CDS uxaC NC_000964.3 1300450 1301871 D catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; uronate isomerase 1300450..1301871 Bacillus subtilis subsp. subtilis str. 168 936461 NP_389113.1 CDS exuM NC_000964.3 1301939 1303318 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9882655; Product type t: transporter; symporter 1301939..1303318 Bacillus subtilis subsp. subtilis str. 168 939410 NP_389114.1 CDS yjmC NC_000964.3 1303423 1304436 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16788182, 9579062, 9882655; Product type pe: enzyme; oxidoreductase 1303423..1304436 Bacillus subtilis subsp. subtilis str. 168 939828 NP_389115.1 CDS yjmD NC_000964.3 1304442 1305461 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9579062, 9882655; Product type pe: enzyme; zinc-type alcohol dehydrogenase 1304442..1305461 Bacillus subtilis subsp. subtilis str. 168 936463 NP_389116.1 CDS uxuA NC_000964.3 1305486 1306565 D catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1305486..1306565 Bacillus subtilis subsp. subtilis str. 168 939409 NP_389117.1 CDS yjmF NC_000964.3 1306562 1307398 D Converts D-mannonate to D-mannuronate; oxidoreductase 1306562..1307398 Bacillus subtilis subsp. subtilis str. 168 939418 NP_389118.1 CDS exuT NC_000964.3 1307446 1308714 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8320243, 9579062, 9882655; Product type t: transporter; hexuronate transporter 1307446..1308714 Bacillus subtilis subsp. subtilis str. 168 939405 NP_389119.1 CDS exuR NC_000964.3 1308802 1309803 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9579062, 9882655; Product type r: regulator; LacI family transcriptional regulator 1308802..1309803 Bacillus subtilis subsp. subtilis str. 168 939834 NP_389120.1 CDS uxaB NC_000964.3 1309880 1311322 D catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1309880..1311322 Bacillus subtilis subsp. subtilis str. 168 936468 NP_389121.2 CDS uxaA NC_000964.3 1311319 1312812 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9579062, 9882655; Product type e: enzyme; altronate dehydratase 1311319..1312812 Bacillus subtilis subsp. subtilis str. 168 939837 NP_389122.1 CDS yjnA NC_000964.3 1312851 1313615 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1312851..1313615) Bacillus subtilis subsp. subtilis str. 168 939412 NP_389123.1 CDS yjoA NC_000964.3 1313840 1314304 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1313840..1314304) Bacillus subtilis subsp. subtilis str. 168 939416 NP_389124.1 CDS yjoB NC_000964.3 1314453 1315724 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14757246; Product type e: enzyme; ATPase YjoB 1314453..1315724 Bacillus subtilis subsp. subtilis str. 168 936467 NP_389125.1 CDS rapA NC_000964.3 1315869 1317005 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587784, 15805512, 15916600; Product type e: enzyme; response regulator aspartate phosphatase A 1315869..1317005 Bacillus subtilis subsp. subtilis str. 168 939417 NP_389126.1 CDS phrA NC_000964.3 1316995 1317129 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 11587784, 16816200; Product type f: factor; phosphatase RapA inhibitor 1316995..1317129 Bacillus subtilis subsp. subtilis str. 168 939413 NP_389127.2 CDS yjpA NC_000964.3 1317157 1317414 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15779043; Product type pe : enzyme; hypothetical protein complement(1317157..1317414) Bacillus subtilis subsp. subtilis str. 168 939831 NP_389128.1 CDS xlyB NC_000964.3 1317535 1318488 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915, 9555893; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase XlyB 1317535..1318488 Bacillus subtilis subsp. subtilis str. 168 936464 NP_389129.1 CDS yjqA NC_000964.3 1318528 1318905 R Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin; hypothetical protein complement(1318528..1318905) Bacillus subtilis subsp. subtilis str. 168 939415 NP_389130.1 CDS yjqB NC_000964.3 1319011 1319613 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin; hypothetical protein 1319011..1319613 Bacillus subtilis subsp. subtilis str. 168 939423 NP_389131.2 CDS yjqC NC_000964.3 1319690 1320526 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin; hypothetical protein 1319690..1320526 Bacillus subtilis subsp. subtilis str. 168 939414 NP_389132.3 CDS xkdA NC_000964.3 1320570 1321166 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267290, 8760915; Product type h: extrachromosomal origin; phage-like element PBSX protein XkdA complement(1320570..1321166) Bacillus subtilis subsp. subtilis str. 168 939838 NP_389133.1 CDS xre NC_000964.3 1321329 1321670 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin; XRE family transcriptional regulator complement(1321329..1321670) Bacillus subtilis subsp. subtilis str. 168 936473 YP_003097711.1 CDS yjzJ NC_000964.3 1321848 1322027 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1321848..1322027 Bacillus subtilis subsp. subtilis str. 168 8303027 NP_389134.2 CDS xkdB NC_000964.3 1322014 1322850 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdB 1322014..1322850 Bacillus subtilis subsp. subtilis str. 168 939420 NP_389135.2 CDS xkdC NC_000964.3 1322750 1323550 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdC 1322750..1323550 Bacillus subtilis subsp. subtilis str. 168 939841 YP_003097712.1 CDS ykzK NC_000964.3 1323550 1323717 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1323550..1323717 Bacillus subtilis subsp. subtilis str. 168 8303179 NP_389136.1 CDS xkdD NC_000964.3 1323802 1324152 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdD 1323802..1324152 Bacillus subtilis subsp. subtilis str. 168 936466 NP_389137.1 CDS xtrA NC_000964.3 1324149 1324355 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915; Product type h : extrachromosomal origin; phage-like element PBSX protein XtrA 1324149..1324355 Bacillus subtilis subsp. subtilis str. 168 939839 NP_389138.1 CDS xpf NC_000964.3 1324471 1324980 D Positive regulatory protein that acts at the late promoter PL; positive control factor 1324471..1324980 Bacillus subtilis subsp. subtilis str. 168 936474 NP_389139.1 CDS xtmA NC_000964.3 1325096 1325893 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8083174; Product type e: enzyme; PBSX phage terminase small subunit 1325096..1325893 Bacillus subtilis subsp. subtilis str. 168 939835 NP_389140.1 CDS xtmB NC_000964.3 1325890 1327191 D Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; PBSX phage terminase large subunit 1325890..1327191 Bacillus subtilis subsp. subtilis str. 168 939426 NP_389141.2 CDS xkdE NC_000964.3 1327195 1328682 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; phage-like element PBSX protein XkdE 1327195..1328682 Bacillus subtilis subsp. subtilis str. 168 936471 NP_389142.2 CDS xkdF NC_000964.3 1328702 1329529 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdF 1328702..1329529 Bacillus subtilis subsp. subtilis str. 168 939833 NP_389143.1 CDS xkdG NC_000964.3 1329555 1330490 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; phage-like element PBSX protein XkdG 1329555..1330490 Bacillus subtilis subsp. subtilis str. 168 939845 YP_003097713.1 CDS ykzL NC_000964.3 1330512 1330895 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1330512..1330895 Bacillus subtilis subsp. subtilis str. 168 8302945 NP_389144.1 CDS xkdH NC_000964.3 1330892 1331248 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdH 1330892..1331248 Bacillus subtilis subsp. subtilis str. 168 936470 NP_389145.1 CDS xkdI NC_000964.3 1331245 1331730 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdI 1331245..1331730 Bacillus subtilis subsp. subtilis str. 168 939425 NP_389146.1 CDS xkdJ NC_000964.3 1331743 1332183 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdJ 1331743..1332183 Bacillus subtilis subsp. subtilis str. 168 936496 YP_003097714.1 CDS ykzM NC_000964.3 1332187 1332405 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1332187..1332405 Bacillus subtilis subsp. subtilis str. 168 8303162 NP_389147.2 CDS xkdK NC_000964.3 1332402 1333802 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdK 1332402..1333802 Bacillus subtilis subsp. subtilis str. 168 939943 NP_389148.1 CDS xkdM NC_000964.3 1333804 1334247 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdM 1333804..1334247 Bacillus subtilis subsp. subtilis str. 168 938181 NP_389149.2 CDS xkdN NC_000964.3 1334339 1334785 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdN 1334339..1334785 Bacillus subtilis subsp. subtilis str. 168 939842 YP_003097715.1 CDS xkzB NC_000964.3 1334815 1334964 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1334815..1334964 Bacillus subtilis subsp. subtilis str. 168 8303192 NP_389150.2 CDS xkdO NC_000964.3 1334966 1338964 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdO 1334966..1338964 Bacillus subtilis subsp. subtilis str. 168 936500 NP_389151.2 CDS xkdP NC_000964.3 1338957 1339616 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; phage-like element PBSX protein XkdP 1338957..1339616 Bacillus subtilis subsp. subtilis str. 168 939946 NP_389152.1 CDS xkdQ NC_000964.3 1339632 1340609 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdQ 1339632..1340609 Bacillus subtilis subsp. subtilis str. 168 938173 NP_389153.1 CDS xkdR NC_000964.3 1340609 1340875 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdR 1340609..1340875 Bacillus subtilis subsp. subtilis str. 168 939427 NP_389154.1 CDS xkdS NC_000964.3 1340932 1341357 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdS 1340932..1341357 Bacillus subtilis subsp. subtilis str. 168 939840 NP_389155.1 CDS xkdT NC_000964.3 1341350 1342396 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; phage-like element PBSX protein XkdT 1341350..1342396 Bacillus subtilis subsp. subtilis str. 168 936475 NP_389156.1 CDS xkdU NC_000964.3 1342380 1342958 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdU 1342380..1342958 Bacillus subtilis subsp. subtilis str. 168 936476 YP_003097716.1 CDS xkzA NC_000964.3 1342955 1343227 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1342955..1343227 Bacillus subtilis subsp. subtilis str. 168 8303196 NP_389158.1 CDS xkdV NC_000964.3 1343230 1345293 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdV 1343230..1345293 Bacillus subtilis subsp. subtilis str. 168 939421 NP_389159.1 CDS xkdW NC_000964.3 1345305 1345634 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdW 1345305..1345634 Bacillus subtilis subsp. subtilis str. 168 936237 NP_389160.1 CDS xkdX NC_000964.3 1345631 1345795 D Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdX 1345631..1345795 Bacillus subtilis subsp. subtilis str. 168 939941 NP_389161.2 CDS xepA NC_000964.3 1345839 1346678 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; phage-like element PBSX protein XepA 1345839..1346678 Bacillus subtilis subsp. subtilis str. 168 938161 NP_389162.1 CDS xhlA NC_000964.3 1346731 1347000 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; phage-like element PBSX protein XhlA 1346731..1347000 Bacillus subtilis subsp. subtilis str. 168 936210 NP_389163.1 CDS xhlB NC_000964.3 1347013 1347276 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2110147, 9555893; Product type h: extrachromosomal origin; holin 1347013..1347276 Bacillus subtilis subsp. subtilis str. 168 939732 NP_389164.1 CDS xlyA NC_000964.3 1347289 1348182 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase XlyA 1347289..1348182 Bacillus subtilis subsp. subtilis str. 168 939869 NP_389165.1 CDS spoIISB NC_000964.3 1348442 1348612 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520; Product type f: factor; stage II sporulation protein SB complement(1348442..1348612) Bacillus subtilis subsp. subtilis str. 168 938005 NP_389166.1 CDS spoIISA NC_000964.3 1348612 1349358 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520, 18096016; Product type f: factor; stage II sporulation protein SA complement(1348612..1349358) Bacillus subtilis subsp. subtilis str. 168 938174 NP_389167.2 CDS pit NC_000964.3 1349468 1350469 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter; low-affinity inorganic phosphate transporter complement(1349468..1350469) Bacillus subtilis subsp. subtilis str. 168 936281 NP_389168.1 CDS ykaA NC_000964.3 1350482 1351099 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696772; Product type pf : factor; hypothetical protein complement(1350482..1351099) Bacillus subtilis subsp. subtilis str. 168 939843 NP_389169.1 CDS ykbA NC_000964.3 1351375 1352691 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; serine/threonine exchanger SteT complement(1351375..1352691) Bacillus subtilis subsp. subtilis str. 168 936518 NP_389170.1 CDS mhqA NC_000964.3 1353080 1354030 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqA 1353080..1354030 Bacillus subtilis subsp. subtilis str. 168 936149 NP_389171.2 CDS ykcB NC_000964.3 1354285 1356435 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; mannosyltransferase YkcB 1354285..1356435 Bacillus subtilis subsp. subtilis str. 168 939775 NP_389172.2 CDS ykcC NC_000964.3 1356447 1357418 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YkcC 1356447..1357418 Bacillus subtilis subsp. subtilis str. 168 936326 NP_389173.2 CDS htrA NC_000964.3 1357936 1359285 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10692364, 11133960, 11555295, 12823817; Product type e: enzyme; serine protease Do-like HtrA complement(1357936..1359285) Bacillus subtilis subsp. subtilis str. 168 939849 NP_389174.1 CDS proG NC_000964.3 1359454 1360272 D catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3 1359454..1360272 Bacillus subtilis subsp. subtilis str. 168 936776 NP_389175.2 CDS dppA NC_000964.3 1360401 1361225 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069674, 11473256; Product type e: enzyme; D-aminopeptidase 1360401..1361225 Bacillus subtilis subsp. subtilis str. 168 936727 NP_389176.1 CDS dppB NC_000964.3 1361242 1362168 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter; dipeptide transport system permease protein DppB 1361242..1362168 Bacillus subtilis subsp. subtilis str. 168 939881 NP_389177.1 CDS dppC NC_000964.3 1362174 1363136 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter; dipeptide transport system permease protein DppC 1362174..1363136 Bacillus subtilis subsp. subtilis str. 168 938038 NP_389178.1 CDS dppD NC_000964.3 1363141 1364148 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7536291; Product type t : transporter; dipeptide transport ATP-binding protein DppD 1363141..1364148 Bacillus subtilis subsp. subtilis str. 168 938628 NP_389179.2 CDS dppE NC_000964.3 1364151 1365800 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 7783641, 8793880; Product type lp: lipoprotein; dipeptide ABC transporter substrate-binding protein 1364151..1365800 Bacillus subtilis subsp. subtilis str. 168 938099 NP_389180.2 CDS ykfA NC_000964.3 1365888 1366847 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10428950, 15101989; Product type pe: enzyme; murein peptide carboxypeptidase 1365888..1366847 Bacillus subtilis subsp. subtilis str. 168 938175 NP_389181.1 CDS ykfB NC_000964.3 1366844 1367944 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11747447, 15101989; Product type e: enzyme; L-Ala-D/L-Glu epimerase 1366844..1367944 Bacillus subtilis subsp. subtilis str. 168 939862 NP_389182.2 CDS ykfC NC_000964.3 1367941 1368831 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type e: enzyme; gamma-D-glutamyl-l-lysine endopeptidase 1367941..1368831 Bacillus subtilis subsp. subtilis str. 168 937979 NP_389183.2 CDS ykfD NC_000964.3 1368844 1369833 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pt : transporter; oligopeptide transport ATP-binding protein YkfD 1368844..1369833 Bacillus subtilis subsp. subtilis str. 168 939863 NP_389184.1 CDS ykgB NC_000964.3 1369876 1370925 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 6-phosphogluconolactonase complement(1369876..1370925) Bacillus subtilis subsp. subtilis str. 168 937980 NP_389185.2 CDS ykgA NC_000964.3 1371015 1371875 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(1371015..1371875) Bacillus subtilis subsp. subtilis str. 168 939864 NP_389186.2 CDS ykhA NC_000964.3 1372035 1372553 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl-CoA thioester hydrolase YkhA 1372035..1372553 Bacillus subtilis subsp. subtilis str. 168 937988 NP_389187.1 CDS hmp NC_000964.3 1372792 1373991 D flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; flavohemoprotein 1372792..1373991 Bacillus subtilis subsp. subtilis str. 168 939891 NP_389188.1 CDS ykzH NC_000964.3 1374068 1374292 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1374068..1374292) Bacillus subtilis subsp. subtilis str. 168 937994 NP_389189.1 CDS ykjA NC_000964.3 1374437 1375168 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1374437..1375168 Bacillus subtilis subsp. subtilis str. 168 939857 NP_389190.1 CDS ykkA NC_000964.3 1375260 1375787 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1375260..1375787 Bacillus subtilis subsp. subtilis str. 168 937079 NP_389191.1 CDS ykkB NC_000964.3 1375777 1376295 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; hypothetical protein 1375777..1376295 Bacillus subtilis subsp. subtilis str. 168 939859 NP_389192.1 CDS ykkC NC_000964.3 1376517 1376855 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter; multidrug resistance protein 1376517..1376855 Bacillus subtilis subsp. subtilis str. 168 936835 NP_389193.1 CDS ykkD NC_000964.3 1376855 1377172 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter; multidrug resistance protein 1376855..1377172 Bacillus subtilis subsp. subtilis str. 168 938109 NP_389194.2 CDS purU NC_000964.3 1377243 1378145 D produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1377243..1378145 Bacillus subtilis subsp. subtilis str. 168 939854 NP_389195.2 CDS proB NC_000964.3 1378496 1379593 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; glutamate 5-kinase 1 1378496..1379593 Bacillus subtilis subsp. subtilis str. 168 936790 NP_389196.2 CDS proA NC_000964.3 1379605 1380852 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1379605..1380852 Bacillus subtilis subsp. subtilis str. 168 936166 NP_389197.1 CDS ohrA NC_000964.3 1380978 1381403 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418552, 17502599; Product type e: enzyme; organic hydroperoxide resistance protein OhrA 1380978..1381403 Bacillus subtilis subsp. subtilis str. 168 939848 NP_389198.1 CDS ohrR NC_000964.3 1381434 1381877 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11983871, 17502599, 18363800; Product type r: regulator; organic hydroperoxide resistance transcriptional regulator complement(1381434..1381877) Bacillus subtilis subsp. subtilis str. 168 939850 NP_389199.1 CDS ohrB NC_000964.3 1382020 1382430 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11418552, 18084074, 9696771; Product type e : enzyme; organic hydroperoxide resistance protein OhrB 1382020..1382430 Bacillus subtilis subsp. subtilis str. 168 936734 YP_003097717.1 CDS ykzN NC_000964.3 1382457 1382627 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1382457..1382627 Bacillus subtilis subsp. subtilis str. 168 8302905 NP_389200.1 CDS guaD NC_000964.3 1382677 1383147 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11101664, 15180998; Product type e: enzyme; guanine deaminase complement(1382677..1383147) Bacillus subtilis subsp. subtilis str. 168 936695 NP_389201.2 CDS metE NC_000964.3 1383320 1385608 R catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase complement(1383320..1385608) Bacillus subtilis subsp. subtilis str. 168 936480 NP_389202.1 CDS ispA NC_000964.3 1386024 1386983 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 3087947; Product type e: enzyme; major intracellular serine protease complement(1386024..1386983) Bacillus subtilis subsp. subtilis str. 168 939934 NP_389203.1 CDS rsbRB NC_000964.3 1387206 1388039 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor; RsbT co-antagonist protein RsbRB 1387206..1388039 Bacillus subtilis subsp. subtilis str. 168 938160 NP_389204.1 CDS thiX NC_000964.3 1388070 1388834 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; HMP/thiamine permease protein YkoC complement(1388070..1388834) Bacillus subtilis subsp. subtilis str. 168 939836 NP_389205.2 CDS thiW NC_000964.3 1388809 1390452 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16291685, 16356850; Product type t: transporter; HMP/thiamine import ATP-binding protein YkoD complement(1388809..1390452) Bacillus subtilis subsp. subtilis str. 168 936472 NP_389206.2 CDS thiV NC_000964.3 1390439 1391038 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; HMP/thiamine permease protein YkoE complement(1390439..1391038) Bacillus subtilis subsp. subtilis str. 168 939829 NP_389207.1 CDS thiU NC_000964.3 1391040 1391642 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15451668, 16291685, 16356850; Product type f: factor; HMP/thiamine-binding protein YkoF complement(1391040..1391642) Bacillus subtilis subsp. subtilis str. 168 936465 NP_389208.1 CDS ykoG NC_000964.3 1391953 1392639 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 1391953..1392639 Bacillus subtilis subsp. subtilis str. 168 936451 NP_389209.1 CDS ykoH NC_000964.3 1392643 1394007 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 1392643..1394007 Bacillus subtilis subsp. subtilis str. 168 936458 NP_389210.1 CDS ykoI NC_000964.3 1394004 1394684 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1394004..1394684 Bacillus subtilis subsp. subtilis str. 168 939827 NP_389211.1 CDS ykoJ NC_000964.3 1394776 1395288 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17209068; Product type ph : phenotype; hypothetical protein 1394776..1395288 Bacillus subtilis subsp. subtilis str. 168 936459 NP_389212.1 CDS ykzD NC_000964.3 1395371 1395508 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1395371..1395508 Bacillus subtilis subsp. subtilis str. 168 936450 NP_389213.1 CDS mgtE NC_000964.3 1396013 1397368 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15096624; Product type t: transporter; magnesium transporter MgtE 1396013..1397368 Bacillus subtilis subsp. subtilis str. 168 936439 NP_389214.1 CDS tnrA NC_000964.3 1397411 1397743 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10231480, 12823818, 15916606, 16547045, 17085574, 17183219; Product type r : regulator; MerR family transcriptional regulator complement(1397411..1397743) Bacillus subtilis subsp. subtilis str. 168 936445 NP_389215.1 CDS ykzB NC_000964.3 1397938 1398093 D Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441; hypothetical protein 1397938..1398093 Bacillus subtilis subsp. subtilis str. 168 939392 NP_389216.1 CDS ykoL NC_000964.3 1398181 1398363 D Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441; stress response protein YkoL 1398181..1398363 Bacillus subtilis subsp. subtilis str. 168 939391 NP_389217.1 CDS ykoM NC_000964.3 1398496 1398960 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 1398496..1398960 Bacillus subtilis subsp. subtilis str. 168 939824 NP_389218.2 CDS ykoN NC_000964.3 1398975 1400096 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase complement(1398975..1400096) Bacillus subtilis subsp. subtilis str. 168 939390 NP_389219.2 CDS ykoP NC_000964.3 1400188 1400739 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1400188..1400739 Bacillus subtilis subsp. subtilis str. 168 936444 NP_389220.1 CDS ykoQ NC_000964.3 1400767 1401579 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase complement(1400767..1401579) Bacillus subtilis subsp. subtilis str. 168 939388 NP_389221.1 CDS ykoS NC_000964.3 1401772 1403466 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1401772..1403466 Bacillus subtilis subsp. subtilis str. 168 939380 NP_389222.1 CDS ykoT NC_000964.3 1403479 1404492 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YkoT 1403479..1404492 Bacillus subtilis subsp. subtilis str. 168 939378 NP_389223.1 CDS ligD NC_000964.3 1404518 1406353 R catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase YkoU complement(1404518..1406353) Bacillus subtilis subsp. subtilis str. 168 939372 NP_389224.1 CDS ykoV NC_000964.3 1406357 1407292 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11095673, 12215643, 16497325, 16780573; Product type e: enzyme; DNA repair protein YkoV complement(1406357..1407292) Bacillus subtilis subsp. subtilis str. 168 939375 YP_054577.1 CDS dgcW NC_000964.3 1407329 1409578 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11728710; Product type prc : receptor; diguanylate cyclase complement(1407329..1409578) Bacillus subtilis subsp. subtilis str. 168 2914252 NP_389226.1 CDS ykoX NC_000964.3 1409912 1410577 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1409912..1410577 Bacillus subtilis subsp. subtilis str. 168 939381 NP_389227.1 CDS ykoY NC_000964.3 1410654 1411628 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter; membrane protein 1410654..1411628 Bacillus subtilis subsp. subtilis str. 168 939368 NP_389228.1 CDS sigI NC_000964.3 1411892 1412647 D Heat shock-induced; RNA polymerase sigma factor SigI 1411892..1412647 Bacillus subtilis subsp. subtilis str. 168 939363 NP_389229.1 CDS rsgI NC_000964.3 1412644 1413789 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17185538; Product type f: factor; anti-sigma-I factor RsgI 1412644..1413789 Bacillus subtilis subsp. subtilis str. 168 939360 NP_389230.1 CDS sspD NC_000964.3 1413800 1413994 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3009397, 3112127, 3121585, 9852018; Product type f: factor; small acid-soluble spore protein D complement(1413800..1413994) Bacillus subtilis subsp. subtilis str. 168 939362 NP_389231.1 CDS ykrK NC_000964.3 1414125 1414826 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1414125..1414826) Bacillus subtilis subsp. subtilis str. 168 939367 NP_389232.1 CDS ykrL NC_000964.3 1414997 1415893 D metalloprotease; protease HtpX homolog 1414997..1415893 Bacillus subtilis subsp. subtilis str. 168 939359 NP_389233.1 CDS ktrD NC_000964.3 1416067 1417416 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406; Product type t: transporter; ktr system potassium uptake protein D 1416067..1417416 Bacillus subtilis subsp. subtilis str. 168 939342 YP_003097718.1 CDS ykzP NC_000964.3 1417561 1417716 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1417561..1417716 Bacillus subtilis subsp. subtilis str. 168 8303057 NP_389234.1 CDS ykzE NC_000964.3 1417719 1417895 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1417719..1417895 Bacillus subtilis subsp. subtilis str. 168 939354 NP_389235.1 CDS ykrP NC_000964.3 1417938 1418960 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane-bound acyltransferase YkrP complement(1417938..1418960) Bacillus subtilis subsp. subtilis str. 168 939356 NP_389236.1 CDS kinE NC_000964.3 1419213 1421429 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 12169614, 16166384; Product type rc: receptor; sporulation kinase E 1419213..1421429 Bacillus subtilis subsp. subtilis str. 168 939349 NP_389237.1 CDS ogt NC_000964.3 1421426 1421923 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2308822, 2359121; Product type e: enzyme; methylated-dna--protein-cysteine methyltransferase 1421426..1421923 Bacillus subtilis subsp. subtilis str. 168 939332 NP_389238.1 CDS mtnA NC_000964.3 1422172 1423233 R isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway; methylthioribose-1-phosphate isomerase complement(1422172..1423233) Bacillus subtilis subsp. subtilis str. 168 939341 NP_389239.1 CDS mtnK NC_000964.3 1423241 1424440 R phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase complement(1423241..1424440) Bacillus subtilis subsp. subtilis str. 168 939336 NP_389240.1 CDS mtnU NC_000964.3 1424767 1425546 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12022921; Product type pe : enzyme; hydrolase complement(1424767..1425546) Bacillus subtilis subsp. subtilis str. 168 939328 NP_389241.1 CDS ykrV NC_000964.3 1425641 1426837 D produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; transaminase MtnE 1425641..1426837 Bacillus subtilis subsp. subtilis str. 168 939330 NP_389242.1 CDS mtnW NC_000964.3 1427034 1428278 D converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 1427034..1428278 Bacillus subtilis subsp. subtilis str. 168 939339 NP_389243.1 CDS mtnX NC_000964.3 1428275 1428982 D converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage; 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase 1428275..1428982 Bacillus subtilis subsp. subtilis str. 168 939331 NP_389244.1 CDS mtnB NC_000964.3 1428940 1429569 D converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage; methylthioribulose-1-phosphate dehydratase 1428940..1429569 Bacillus subtilis subsp. subtilis str. 168 939320 NP_389245.1 CDS mtnD NC_000964.3 1429584 1430120 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10704478, 11371200, 12022880, 12402029, 15102328; Product type e: enzyme; acireductone dioxygenase 1429584..1430120 Bacillus subtilis subsp. subtilis str. 168 939322 NP_389246.1 CDS ykvA NC_000964.3 1430161 1430481 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(1430161..1430481) Bacillus subtilis subsp. subtilis str. 168 939314 NP_389247.1 CDS spo0E NC_000964.3 1430684 1430941 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15057450, 15916600; Product type e: enzyme; aspartyl-phosphate phosphatase Spo0E 1430684..1430941 Bacillus subtilis subsp. subtilis str. 168 939315 NP_389248.1 CDS eag NC_000964.3 1431027 1431458 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1431027..1431458 Bacillus subtilis subsp. subtilis str. 168 939325 NP_389249.1 CDS kinD NC_000964.3 1431486 1433006 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 16166384, 10411754; Product type e: enzyme; sporulation kinase D complement(1431486..1433006) Bacillus subtilis subsp. subtilis str. 168 939300 NP_389250.1 CDS mhqR NC_000964.3 1433199 1433636 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17725564; Product type r: regulator; MarR family transcriptional regulator 1433199..1433636 Bacillus subtilis subsp. subtilis str. 168 939303 NP_389251.1 CDS motB NC_000964.3 1433676 1434461 R with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; motility protein B complement(1433676..1434461) Bacillus subtilis subsp. subtilis str. 168 939304 NP_389252.1 CDS motA NC_000964.3 1434433 1435245 R With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; motility protein A complement(1434433..1435245) Bacillus subtilis subsp. subtilis str. 168 939302 NP_389253.1 CDS clpE NC_000964.3 1435628 1437727 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788169, 16899079, 11069659, 9987115, 10320580; Product type e: enzyme; ATP-dependent Clp protease ATP-binding subunit ClpE complement(1435628..1437727) Bacillus subtilis subsp. subtilis str. 168 939289 NP_389254.1 CDS ykvI NC_000964.3 1438092 1439135 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836, 15849754, 16850406; Product type pt: transporter; membrane protein 1438092..1439135 Bacillus subtilis subsp. subtilis str. 168 939307 NP_389255.1 CDS queC NC_000964.3 1439448 1440107 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14660578, 16199558, 17384645, 18491386; Product type e: enzyme; 7-cyano-7-deazaguanine synthase 1439448..1440107 Bacillus subtilis subsp. subtilis str. 168 939292 NP_389256.1 CDS queD NC_000964.3 1440100 1440549 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558, 18259064; Product type e: enzyme; 6-pyruvoyl tetrahydrobiopterin synthase 1440100..1440549 Bacillus subtilis subsp. subtilis str. 168 939282 NP_389257.1 CDS queE NC_000964.3 1440542 1441273 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558; Product type e : enzyme; 7-carboxy-7-deazaguanine synthase 1440542..1441273 Bacillus subtilis subsp. subtilis str. 168 939290 NP_389258.1 CDS ykvM NC_000964.3 1441291 1441788 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; NADPH-dependent 7-cyano-7-deazaguanine reductase 1441291..1441788 Bacillus subtilis subsp. subtilis str. 168 939296 NP_389259.1 CDS ykvN NC_000964.3 1442347 1442703 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pr : regulator; HxlR family transcriptional regulator complement(1442347..1442703) Bacillus subtilis subsp. subtilis str. 168 939274 NP_389260.1 CDS ykvO NC_000964.3 1442872 1443618 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; oxidoreductase 1442872..1443618 Bacillus subtilis subsp. subtilis str. 168 939276 NP_389261.1 CDS ykvP NC_000964.3 1444099 1445298 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 16683018; Product type f: factor; spore protein YkvP 1444099..1445298 Bacillus subtilis subsp. subtilis str. 168 939278 YP_003097719.1 CDS ykzQ NC_000964.3 1445314 1445541 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1445314..1445541 Bacillus subtilis subsp. subtilis str. 168 8303133 NP_389262.1 CDS ykvQ NC_000964.3 1445638 1446336 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; glycosylase YkvQ 1445638..1446336 Bacillus subtilis subsp. subtilis str. 168 939273 YP_003097720.1 CDS ykzR NC_000964.3 1446317 1446568 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; spore-specific glycosyl hydrolase 1446317..1446568 Bacillus subtilis subsp. subtilis str. 168 8303134 NP_389263.1 CDS ykvR NC_000964.3 1447251 1447541 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1447251..1447541 Bacillus subtilis subsp. subtilis str. 168 939743 NP_389264.2 CDS ykvS NC_000964.3 1447662 1447847 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1447662..1447847) Bacillus subtilis subsp. subtilis str. 168 939299 YP_003097721.1 CDS ykzS NC_000964.3 1448013 1448207 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1448013..1448207 Bacillus subtilis subsp. subtilis str. 168 8302968 NP_389265.1 CDS ykvT NC_000964.3 1448506 1449132 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12177332, 12950927; Product type e : enzyme; hypothetical protein 1448506..1449132 Bacillus subtilis subsp. subtilis str. 168 939264 NP_389266.1 CDS ykvU NC_000964.3 1449250 1450587 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15686839, 15849754, 16850406; Product type m: membrane component; sporulation protein YkvU 1449250..1450587 Bacillus subtilis subsp. subtilis str. 168 939262 NP_389267.1 CDS stoA NC_000964.3 1450638 1451135 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15322369, 15342593; Product type e: enzyme; sporulation thiol-disulfide oxidoreductase A 1450638..1451135 Bacillus subtilis subsp. subtilis str. 168 936262 NP_389268.1 CDS zosA NC_000964.3 1451371 1453284 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12180919, 15802251; Product type t: transporter; zinc-transporting ATPase 1451371..1453284 Bacillus subtilis subsp. subtilis str. 168 939268 NP_389269.1 CDS ykvY NC_000964.3 1453691 1454782 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7770058; Product type pe : enzyme; dipeptidase YkvY 1453691..1454782 Bacillus subtilis subsp. subtilis str. 168 939258 NP_389270.1 CDS ykvZ NC_000964.3 1455064 1456029 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LacI family transcriptional regulator 1455064..1456029 Bacillus subtilis subsp. subtilis str. 168 936232 NP_389271.2 CDS glcT NC_000964.3 1456092 1456958 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974121, 15155854, 17074746; Product type r: regulator; BglG family transcription antiterminator 1456092..1456958 Bacillus subtilis subsp. subtilis str. 168 939254 NP_389272.1 CDS ptsG NC_000964.3 1457187 1459286 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1447219, 14527945, 15849754, 16850406, 8418852, 8432747, 9593197; Product type t: transporter; PTS system glucose-specific EIICBA component 1457187..1459286 Bacillus subtilis subsp. subtilis str. 168 939255 NP_389273.1 CDS ptsH NC_000964.3 1459384 1459650 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217795, 12411438, 14527945, 15126459, 16267306, 17085448, 17142398; Product type f: factor; phosphocarrier protein HPr 1459384..1459650 Bacillus subtilis subsp. subtilis str. 168 939259 NP_389274.2 CDS ptsI NC_000964.3 1459650 1461362 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902727, 15155854, 15670601, 3106335; Product type e: enzyme; phosphoenolpyruvate-protein phosphotransferase 1459650..1461362 Bacillus subtilis subsp. subtilis str. 168 939253 NP_389275.1 CDS splA NC_000964.3 1461453 1461692 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 9009064, 9323362; Product type r: regulator; transcriptional regulator SplA 1461453..1461692 Bacillus subtilis subsp. subtilis str. 168 939728 NP_389276.1 CDS splB NC_000964.3 1461770 1462798 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 11053385, 11470912, 17293412, 9733691; Product type e: enzyme; spore photoproduct lyase 1461770..1462798 Bacillus subtilis subsp. subtilis str. 168 939248 NP_389277.2 CDS ykwB NC_000964.3 1462813 1463493 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YkwB complement(1462813..1463493) Bacillus subtilis subsp. subtilis str. 168 939246 NP_389278.2 CDS mcpC NC_000964.3 1463628 1465595 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11722727, 12603740, 15317802, 9721285; Product type rc: receptor; methyl-accepting chemotaxis protein McpC 1463628..1465595 Bacillus subtilis subsp. subtilis str. 168 936206 NP_389279.1 CDS ykwC NC_000964.3 1465733 1466599 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1465733..1466599 Bacillus subtilis subsp. subtilis str. 168 939723 NP_389280.2 CDS ykwD NC_000964.3 1466638 1467411 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1466638..1467411) Bacillus subtilis subsp. subtilis str. 168 939237 NP_389281.1 CDS pbpH NC_000964.3 1467805 1469862 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990; Product type e: enzyme; penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall 1467805..1469862 Bacillus subtilis subsp. subtilis str. 168 936204 NP_389282.1 CDS kinA NC_000964.3 1470026 1471846 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11734624, 14629015, 17350039; Product type cp: cell process; sporulation kinase A 1470026..1471846 Bacillus subtilis subsp. subtilis str. 168 939230 NP_389283.2 CDS patA NC_000964.3 1471857 1473038 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12670965; Product type e: enzyme; N-acetyl-LL-diaminopimelate aminotransferase complement(1471857..1473038) Bacillus subtilis subsp. subtilis str. 168 939235 YP_003097722.1 CDS ykzT NC_000964.3 1473240 1473401 R Evidence 6: Doubtful CDS; hypothetical protein complement(1473240..1473401) Bacillus subtilis subsp. subtilis str. 168 8303007 NP_389284.1 CDS cheV NC_000964.3 1473605 1474516 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11553614, 12864845, 14731274, 14993307; Product type r: regulator; chemotaxis protein CheV 1473605..1474516 Bacillus subtilis subsp. subtilis str. 168 939239 NP_389285.1 CDS ykyB NC_000964.3 1474560 1475024 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1474560..1475024) Bacillus subtilis subsp. subtilis str. 168 939225 NP_389286.2 CDS ykuC NC_000964.3 1475150 1476442 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(1475150..1476442) Bacillus subtilis subsp. subtilis str. 168 939224 NP_389287.1 CDS ykuD NC_000964.3 1476518 1477012 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148; Product type cp: cell process; L,D-transpeptidase YkuD complement(1476518..1477012) Bacillus subtilis subsp. subtilis str. 168 939216 NP_389288.2 CDS ykuE NC_000964.3 1477069 1477929 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase complement(1477069..1477929) Bacillus subtilis subsp. subtilis str. 168 939214 NP_389289.1 CDS ykuF NC_000964.3 1478072 1478836 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; 2,4-dienoyl-CoA reductase 1478072..1478836 Bacillus subtilis subsp. subtilis str. 168 939226 YP_003097723.1 CDS fadG NC_000964.3 1479137 1480867 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250; hypothetical protein 1479137..1480867 Bacillus subtilis subsp. subtilis str. 168 8303034 YP_003097724.1 CDS ykzU NC_000964.3 1480933 1481451 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1480933..1481451 Bacillus subtilis subsp. subtilis str. 168 8303033 NP_389291.1 CDS ykuH NC_000964.3 1481547 1482095 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1481547..1482095 Bacillus subtilis subsp. subtilis str. 168 939211 NP_389292.1 CDS ykuI NC_000964.3 1482248 1483471 D Evidence 4: Homologs of previously reported genes of unknown function; EAL-domain containing protein YkuI 1482248..1483471 Bacillus subtilis subsp. subtilis str. 168 939207 NP_389293.1 CDS ykuJ NC_000964.3 1484117 1484356 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1484117..1484356 Bacillus subtilis subsp. subtilis str. 168 936162 NP_389294.1 CDS ykuK NC_000964.3 1484466 1484984 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16165328; Product type pe : enzyme; hypothetical protein 1484466..1484984 Bacillus subtilis subsp. subtilis str. 168 939213 NP_389295.1 CDS ykzF NC_000964.3 1485118 1485315 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1485118..1485315 Bacillus subtilis subsp. subtilis str. 168 939703 NP_389296.1 CDS ykuL NC_000964.3 1485453 1485896 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717; CBS domain-containing protein YkuL 1485453..1485896 Bacillus subtilis subsp. subtilis str. 168 939199 NP_389297.1 CDS ccpC NC_000964.3 1486045 1486926 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636591, 16352834, 16395550; Product type r: regulator; LysR family transcriptional regulator 1486045..1486926 Bacillus subtilis subsp. subtilis str. 168 939197 NP_389298.1 CDS ykuN NC_000964.3 1487038 1487514 D An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1487038..1487514 Bacillus subtilis subsp. subtilis str. 168 939194 NP_389299.1 CDS ykuO NC_000964.3 1487504 1488397 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229; hypothetical protein 1487504..1488397 Bacillus subtilis subsp. subtilis str. 168 939196 NP_389300.2 CDS ykuP NC_000964.3 1488413 1488868 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15449930, 17127770; Product type e: enzyme; flavodoxin-2 1488413..1488868 Bacillus subtilis subsp. subtilis str. 168 938811 NP_389301.2 CDS dapH NC_000964.3 1488973 1489683 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368155, 11910040, 12682299, 14627808; Product type e: enzyme; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 1488973..1489683 Bacillus subtilis subsp. subtilis str. 168 939193 NP_389302.1 CDS dapL NC_000964.3 1489753 1490877 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14627808, 17093042; Product type e : enzyme; N-acetyldiaminopimelate deacetylase 1489753..1490877 Bacillus subtilis subsp. subtilis str. 168 938805 NP_389303.1 CDS ykuS NC_000964.3 1490939 1491184 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1490939..1491184 Bacillus subtilis subsp. subtilis str. 168 938799 NP_389304.2 CDS ykuT NC_000964.3 1491221 1492024 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12626684; Product type pt : transporter; MscS family protein YkuT complement(1491221..1492024) Bacillus subtilis subsp. subtilis str. 168 938809 NP_389305.1 CDS ykuU NC_000964.3 1492261 1492803 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; thioredoxin 1492261..1492803 Bacillus subtilis subsp. subtilis str. 168 938810 NP_389306.2 CDS ykuV NC_000964.3 1492875 1493321 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16418167; Product type e: enzyme; thiol-disulfide oxidoreductase 1492875..1493321 Bacillus subtilis subsp. subtilis str. 168 938804 NP_389307.1 CDS rok NC_000964.3 1493787 1494362 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619; Product type r: regulator; repressor rok 1493787..1494362 Bacillus subtilis subsp. subtilis str. 168 938793 NP_389308.1 CDS yknT NC_000964.3 1494403 1495368 R Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949; sporulation protein cse15 complement(1494403..1495368) Bacillus subtilis subsp. subtilis str. 168 938787 NP_389309.1 CDS mobA NC_000964.3 1495505 1496104 D Evidence 2b: Function of strongly homologous gene; PubMedId: 10978347; Product type e: enzyme; molybdenum cofactor guanylyltransferase 1495505..1496104 Bacillus subtilis subsp. subtilis str. 168 938791 NP_389310.1 CDS moeB NC_000964.3 1496155 1497174 D catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; molybdopterin-synthase adenylyltransferase 1496155..1497174 Bacillus subtilis subsp. subtilis str. 168 938780 NP_389311.1 CDS moeA NC_000964.3 1497192 1498484 D Evidence 2b: Function of strongly homologous gene; PubMedId: 11428898, 12006571; Product type e : enzyme; molybdopterin molybdenumtransferase 1497192..1498484 Bacillus subtilis subsp. subtilis str. 168 938797 NP_389312.1 CDS mobB NC_000964.3 1498445 1498966 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12719427, 9219527; Product type c : carrier; molybdopterin-guanine dinucleotide biosynthesis adapter protein 1498445..1498966 Bacillus subtilis subsp. subtilis str. 168 938790 NP_389313.1 CDS moaE NC_000964.3 1498966 1499439 D Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669; Product type e: enzyme; molybdopterin synthase catalytic subunit 1498966..1499439 Bacillus subtilis subsp. subtilis str. 168 936092 NP_389314.1 CDS moaD NC_000964.3 1499432 1499665 D Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669, 17223713; Product type e : enzyme; molybdopterin synthase sulfur carrier subunit 1499432..1499665 Bacillus subtilis subsp. subtilis str. 168 938785 NP_389315.1 CDS yknU NC_000964.3 1499889 1501646 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 1499889..1501646 Bacillus subtilis subsp. subtilis str. 168 938775 NP_389316.1 CDS yknV NC_000964.3 1501658 1503472 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 1501658..1503472 Bacillus subtilis subsp. subtilis str. 168 936087 NP_389317.1 CDS yknW NC_000964.3 1503582 1504277 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 1503582..1504277 Bacillus subtilis subsp. subtilis str. 168 938771 NP_389318.1 CDS yknX NC_000964.3 1504282 1505415 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter; efflux system component YknX 1504282..1505415 Bacillus subtilis subsp. subtilis str. 168 938774 NP_389319.1 CDS yknY NC_000964.3 1505416 1506108 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter; ABC transporter ATP-binding protein 1505416..1506108 Bacillus subtilis subsp. subtilis str. 168 938766 NP_389320.1 CDS yknZ NC_000964.3 1506105 1507298 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter; ABC transporter permease 1506105..1507298 Bacillus subtilis subsp. subtilis str. 168 938803 NP_389321.1 CDS fruR NC_000964.3 1507578 1508333 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858; Product type r: regulator; DeoR family transcriptional regulator 1507578..1508333 Bacillus subtilis subsp. subtilis str. 168 936082 NP_389322.1 CDS fruK NC_000964.3 1508330 1509241 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858, 168069; Product type e: enzyme; phosphofructokinase 1508330..1509241 Bacillus subtilis subsp. subtilis str. 168 938761 NP_389323.1 CDS fruA NC_000964.3 1509256 1511163 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 118007, 200418; Product type t: transporter; PTS system fructose-specific EIIABC component 1509256..1511163 Bacillus subtilis subsp. subtilis str. 168 938757 NP_389324.1 CDS sipT NC_000964.3 1511308 1511889 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10198007, 11283286, 12897006, 9325333; Product type e: enzyme; signal peptidase I T 1511308..1511889 Bacillus subtilis subsp. subtilis str. 168 938763 NP_389325.1 CDS ykoA NC_000964.3 1511923 1512192 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1511923..1512192) Bacillus subtilis subsp. subtilis str. 168 938768 NP_389326.1 CDS ykpA NC_000964.3 1512373 1513995 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10816464; Product type t: transporter; ABC transporter ATP-binding protein 1512373..1513995 Bacillus subtilis subsp. subtilis str. 168 936066 NP_389327.1 CDS ykpB NC_000964.3 1514052 1514963 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15966718, 17229734; Product type e: enzyme; oxidoreductase 1514052..1514963 Bacillus subtilis subsp. subtilis str. 168 938752 NP_389328.1 CDS ampS NC_000964.3 1514997 1516229 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16088219, 9362117; Product type e: enzyme; aminopeptidase AmpS complement(1514997..1516229) Bacillus subtilis subsp. subtilis str. 168 938756 NP_389329.1 CDS ykpC NC_000964.3 1516339 1516473 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1516339..1516473) Bacillus subtilis subsp. subtilis str. 168 938750 NP_389330.1 CDS mreBH NC_000964.3 1516574 1517581 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16950129; Product type f: factor; rod-share determining protein MreBH complement(1516574..1517581) Bacillus subtilis subsp. subtilis str. 168 938746 NP_389331.1 CDS abh NC_000964.3 1517865 1518143 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 17720793; Product type r: regulator; transition state regulator Abh 1517865..1518143 Bacillus subtilis subsp. subtilis str. 168 938738 NP_389332.1 CDS kinC NC_000964.3 1518333 1519619 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 7836330; Product type e: enzyme; sporulation kinase C 1518333..1519619 Bacillus subtilis subsp. subtilis str. 168 938742 NP_389333.1 CDS ykqA NC_000964.3 1519635 1520468 D Evidence 4: Homologs of previously reported genes of unknown function; gamma-glutamylcyclotransferase YkqA 1519635..1520468 Bacillus subtilis subsp. subtilis str. 168 939408 NP_389334.1 CDS ktrC NC_000964.3 1520531 1521196 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter; ktr system potassium uptake protein C 1520531..1521196 Bacillus subtilis subsp. subtilis str. 168 939429 NP_389335.2 CDS adeC NC_000964.3 1521351 1523084 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8550522; Product type e : enzyme; adenine deaminase 1521351..1523084 Bacillus subtilis subsp. subtilis str. 168 939477 NP_389336.1 CDS rnjA NC_000964.3 1523118 1524785 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15831787, 17005971, 17229210, 17512403, 18713320; Product type e : enzyme; ribonuclease J 1 complement(1523118..1524785) Bacillus subtilis subsp. subtilis str. 168 939483 NP_389337.1 CDS ykzG NC_000964.3 1524791 1525000 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1524791..1525000) Bacillus subtilis subsp. subtilis str. 168 939482 NP_389338.1 CDS ykrA NC_000964.3 1525386 1526159 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YkrA 1525386..1526159 Bacillus subtilis subsp. subtilis str. 168 939479 NP_389339.1 CDS def NC_000964.3 1526195 1526749 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1526195..1526749) Bacillus subtilis subsp. subtilis str. 168 939491 YP_003097725.1 CDS ykzV NC_000964.3 1526859 1527017 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1526859..1527017) Bacillus subtilis subsp. subtilis str. 168 8303091 NP_389340.2 CDS ykyA NC_000964.3 1527231 1527902 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16684363; Product type pf : factor; lipoprotein 1527231..1527902 Bacillus subtilis subsp. subtilis str. 168 939487 NP_389341.1 CDS pdhA NC_000964.3 1528326 1529441 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 1784816, 9352926, 9588797; Product type e: enzyme; pyruvate dehydrogenase E1 component subunit alpha 1528326..1529441 Bacillus subtilis subsp. subtilis str. 168 936005 NP_389342.1 CDS pdhB NC_000964.3 1529445 1530422 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme; pyruvate dehydrogenase E1 component subunit beta 1529445..1530422 Bacillus subtilis subsp. subtilis str. 168 939496 NP_389343.1 CDS pdhC NC_000964.3 1530537 1531865 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 1530537..1531865 Bacillus subtilis subsp. subtilis str. 168 936010 NP_389344.1 CDS pdhD NC_000964.3 1531870 1533282 D E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase 1531870..1533282 Bacillus subtilis subsp. subtilis str. 168 939492 NP_389345.1 CDS slp NC_000964.3 1533327 1533701 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1936936; Product type s : structure; Pal-related lipoprotein complement(1533327..1533701) Bacillus subtilis subsp. subtilis str. 168 935991 YP_003097726.1 CDS ykzW NC_000964.3 1534120 1534239 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1534120..1534239 Bacillus subtilis subsp. subtilis str. 168 8302953 NP_389346.1 CDS speA NC_000964.3 1534279 1535751 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9723923; Product type e : enzyme; arginine decarboxylase complement(1534279..1535751) Bacillus subtilis subsp. subtilis str. 168 936002 NP_389347.1 CDS yktA NC_000964.3 1535936 1536202 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1535936..1536202 Bacillus subtilis subsp. subtilis str. 168 935989 NP_389348.1 CDS yktB NC_000964.3 1536235 1536873 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1536235..1536873) Bacillus subtilis subsp. subtilis str. 168 935987 NP_389349.1 CDS ykzI NC_000964.3 1537113 1537301 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1537113..1537301 Bacillus subtilis subsp. subtilis str. 168 935992 NP_389350.1 CDS suhB NC_000964.3 1537441 1538238 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11914086, 16682444; Product type e: enzyme; inositol-1-monophosphatase 1537441..1538238 Bacillus subtilis subsp. subtilis str. 168 935986 NP_389351.1 CDS ykzC NC_000964.3 1538264 1538692 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1538264..1538692 Bacillus subtilis subsp. subtilis str. 168 935976 NP_389352.1 CDS yktD NC_000964.3 1538770 1539684 R Evidence 4: Homologs of previously reported genes of unknown function; S-adenosyl-L-methionine-dependent methyltransferase YktD complement(1538770..1539684) Bacillus subtilis subsp. subtilis str. 168 935978 NP_389353.1 CDS nprE NC_000964.3 1540036 1541601 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 2128597, 6090407, 8436952; Product type e: enzyme; bacillolysin complement(1540036..1541601) Bacillus subtilis subsp. subtilis str. 168 935981 NP_389354.1 CDS ylaA NC_000964.3 1541886 1543826 D Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307; hypothetical protein 1541886..1543826 Bacillus subtilis subsp. subtilis str. 168 935984 NP_389355.1 CDS ylaB NC_000964.3 1543816 1544085 D Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307; hypothetical protein 1543816..1544085 Bacillus subtilis subsp. subtilis str. 168 935962 NP_389356.1 CDS ylaC NC_000964.3 1544085 1544606 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator; RNA polymerase sigma factor YlaC 1544085..1544606 Bacillus subtilis subsp. subtilis str. 168 935973 NP_389357.1 CDS ylaD NC_000964.3 1544603 1544896 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator; anti-sigma-YlaC factor YlaD 1544603..1544896 Bacillus subtilis subsp. subtilis str. 168 935961 NP_389358.1 CDS ylaE NC_000964.3 1544936 1545547 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(1544936..1545547) Bacillus subtilis subsp. subtilis str. 168 935955 NP_389359.1 CDS ylaF NC_000964.3 1545820 1546008 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1545820..1546008) Bacillus subtilis subsp. subtilis str. 168 935954 NP_389360.1 CDS bipA NC_000964.3 1546121 1547959 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11683274, 12399512, 9642082; Product type e : enzyme; GTP-binding protein TypA/BipA homolog 1546121..1547959 Bacillus subtilis subsp. subtilis str. 168 935966 NP_389361.1 CDS ylaH NC_000964.3 1548016 1548333 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1548016..1548333 Bacillus subtilis subsp. subtilis str. 168 935937 NP_389362.1 CDS ylaI NC_000964.3 1548389 1548598 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1548389..1548598) Bacillus subtilis subsp. subtilis str. 168 935943 NP_389363.1 CDS ylaJ NC_000964.3 1548681 1549310 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein complement(1548681..1549310) Bacillus subtilis subsp. subtilis str. 168 935926 NP_389364.1 CDS ylaK NC_000964.3 1549465 1550793 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12762842; Product type pf : factor; hypothetical protein 1549465..1550793 Bacillus subtilis subsp. subtilis str. 168 935933 NP_389365.1 CDS ylaL NC_000964.3 1550797 1551282 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1550797..1551282) Bacillus subtilis subsp. subtilis str. 168 935944 NP_389366.1 CDS ylaM NC_000964.3 1551385 1552314 D catalyzes the formation of glutamate from glutamine; glutaminase 1551385..1552314 Bacillus subtilis subsp. subtilis str. 168 939852 NP_389367.1 CDS ylaN NC_000964.3 1552412 1552693 D depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein; hypothetical protein 1552412..1552693 Bacillus subtilis subsp. subtilis str. 168 936566 NP_389368.1 CDS ftsW NC_000964.3 1552899 1554110 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12626683, 15849754, 16850406, 9622350; Product type t: transporter; lipid II flippase FtsW 1552899..1554110 Bacillus subtilis subsp. subtilis str. 168 935918 NP_389369.1 CDS pycA NC_000964.3 1554185 1557631 D biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1554185..1557631 Bacillus subtilis subsp. subtilis str. 168 935920 NP_389370.1 CDS ctaA NC_000964.3 1558034 1558954 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12206660, 15491161, 15849754, 16321940, 16850406; Product type e: enzyme; heme A synthase complement(1558034..1558954) Bacillus subtilis subsp. subtilis str. 168 937030 NP_389371.1 CDS ctaB NC_000964.3 1559309 1560226 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2 1559309..1560226 Bacillus subtilis subsp. subtilis str. 168 935922 NP_389372.1 CDS ctaC NC_000964.3 1560466 1561536 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1685007, 1847686, 9829923, 9882689; Product type e: enzyme; cytochrome c oxidase subunit 2 1560466..1561536 Bacillus subtilis subsp. subtilis str. 168 936789 NP_389373.2 CDS ctaD NC_000964.3 1561569 1563437 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15849754, 1685007, 16850406, 1847686; Product type e: enzyme; cytochrome c oxidase subunit 1 1561569..1563437 Bacillus subtilis subsp. subtilis str. 168 936898 NP_389374.1 CDS ctaE NC_000964.3 1563437 1564060 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1847686; Product type e: enzyme; cytochrome c oxidase subunit 3 1563437..1564060 Bacillus subtilis subsp. subtilis str. 168 935993 NP_389375.1 CDS ctaF NC_000964.3 1564063 1564395 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1847686; Product type e : enzyme; cytochrome c oxidase subunit 4B 1564063..1564395 Bacillus subtilis subsp. subtilis str. 168 936259 NP_389376.1 CDS ctaG NC_000964.3 1564422 1565315 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766920, 15849754, 16305244, 16850406; Product type f: factor; cytochrome c oxidase assembly factor CtaG 1564422..1565315 Bacillus subtilis subsp. subtilis str. 168 939909 NP_389377.1 CDS ylbA NC_000964.3 1565347 1565709 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1565347..1565709) Bacillus subtilis subsp. subtilis str. 168 939858 NP_389378.2 CDS ylbB NC_000964.3 1565849 1566295 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1565849..1566295 Bacillus subtilis subsp. subtilis str. 168 938107 NP_389379.1 CDS ylbC NC_000964.3 1566379 1567419 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1566379..1567419 Bacillus subtilis subsp. subtilis str. 168 937363 NP_389380.1 CDS ylbD NC_000964.3 1567651 1568049 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1567651..1568049 Bacillus subtilis subsp. subtilis str. 168 936929 NP_389381.1 CDS ylbE NC_000964.3 1568065 1568304 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1568065..1568304 Bacillus subtilis subsp. subtilis str. 168 938216 NP_389382.1 CDS ylbF NC_000964.3 1568420 1568869 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10712692, 15175311, 15661000; Product type pr: regulator; regulatory protein YlbF 1568420..1568869 Bacillus subtilis subsp. subtilis str. 168 939945 NP_389383.1 CDS ylbG NC_000964.3 1568924 1569196 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1568924..1569196 Bacillus subtilis subsp. subtilis str. 168 939846 NP_389384.2 CDS ylbH NC_000964.3 1569519 1570073 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; rRNA methyltransferase YlbH 1569519..1570073 Bacillus subtilis subsp. subtilis str. 168 936402 NP_389385.1 CDS coaD NC_000964.3 1570078 1570563 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1570078..1570563 Bacillus subtilis subsp. subtilis str. 168 936889 NP_389386.1 CDS ylbJ NC_000964.3 1570574 1571800 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type cp: cell process; sporulation integral membrane protein YlbJ complement(1570574..1571800) Bacillus subtilis subsp. subtilis str. 168 936629 NP_389387.1 CDS ylbK NC_000964.3 1571981 1572763 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NTE family protein YlbK 1571981..1572763 Bacillus subtilis subsp. subtilis str. 168 936382 NP_389388.2 CDS ylbL NC_000964.3 1572765 1573790 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1572765..1573790 Bacillus subtilis subsp. subtilis str. 168 936755 NP_389389.1 CDS ylbM NC_000964.3 1573807 1575054 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1573807..1575054) Bacillus subtilis subsp. subtilis str. 168 936548 YP_003097727.1 CDS ylzH NC_000964.3 1575051 1575236 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(1575051..1575236) Bacillus subtilis subsp. subtilis str. 168 8303049 NP_389390.1 CDS ylbN NC_000964.3 1575264 1575782 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11700356; hypothetical protein 1575264..1575782 Bacillus subtilis subsp. subtilis str. 168 936788 NP_389391.1 CDS rpmF NC_000964.3 1575804 1575983 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1575804..1575983 Bacillus subtilis subsp. subtilis str. 168 939855 NP_389392.1 CDS ylbO NC_000964.3 1576129 1576710 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15621419; Product type cp: cell process; hypothetical protein 1576129..1576710 Bacillus subtilis subsp. subtilis str. 168 935998 NP_389393.2 CDS ylbP NC_000964.3 1576767 1577249 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YlbP complement(1576767..1577249) Bacillus subtilis subsp. subtilis str. 168 939853 NP_389394.1 CDS ylbQ NC_000964.3 1577409 1578305 D ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1577409..1578305 Bacillus subtilis subsp. subtilis str. 168 936782 NP_389395.2 CDS yllA NC_000964.3 1578376 1579995 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16169927; Product type pf : factor; hypothetical protein 1578376..1579995 Bacillus subtilis subsp. subtilis str. 168 939844 NP_389396.1 CDS yllB NC_000964.3 1580121 1580552 D MraZ; UPF0040; crystal structure shows similarity to AbrB; protein MraZ 1580121..1580552 Bacillus subtilis subsp. subtilis str. 168 935932 NP_389397.1 CDS mraW NC_000964.3 1580622 1581557 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10572301, 16849811; Product type e: enzyme; ribosomal RNA small subunit methyltransferase H 1580622..1581557 Bacillus subtilis subsp. subtilis str. 168 936555 NP_389398.1 CDS ftsL NC_000964.3 1581597 1581950 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10792716, 10844672, 11994149, 16549676, 16936019, 17020588; Product type cp : cell process; cell division protein FtsL 1581597..1581950 Bacillus subtilis subsp. subtilis str. 168 939860 NP_389399.2 CDS pbpB NC_000964.3 1581947 1584097 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14731276, 8636036; Product type cp: cell process; penicillin-binding protein 2B 1581947..1584097 Bacillus subtilis subsp. subtilis str. 168 939847 NP_389400.2 CDS spoVD NC_000964.3 1584214 1586154 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8244929, 8289242, 9006059; Product type cp: cell process; stage V sporulation protein D 1584214..1586154 Bacillus subtilis subsp. subtilis str. 168 936661 NP_389401.1 CDS murE NC_000964.3 1586330 1587814 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase 1586330..1587814 Bacillus subtilis subsp. subtilis str. 168 937567 NP_389402.2 CDS mraY NC_000964.3 1587926 1588900 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-n-acetylmuramoyl-pentapeptide- transferase 1587926..1588900 Bacillus subtilis subsp. subtilis str. 168 939856 NP_389403.1 CDS murD NC_000964.3 1588901 1590256 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoylalanine--D-glutamate ligase 1588901..1590256 Bacillus subtilis subsp. subtilis str. 168 935950 NP_389404.1 CDS spoVE NC_000964.3 1590317 1591417 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16484183, 16850406, 2509435, 9622350; Product type cp: cell process; stage V sporulation protein E 1590317..1591417 Bacillus subtilis subsp. subtilis str. 168 936953 NP_389405.2 CDS murG NC_000964.3 1591540 1592631 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1591540..1592631 Bacillus subtilis subsp. subtilis str. 168 935929 NP_389406.1 CDS murB NC_000964.3 1592663 1593574 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1592663..1593574 Bacillus subtilis subsp. subtilis str. 168 939804 NP_389407.1 CDS divIB NC_000964.3 1593704 1594495 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10852898, 12682299, 15659156, 16618922, 16936019, 16936026; Product type cp : cell process; cell division protein DivIB 1593704..1594495 Bacillus subtilis subsp. subtilis str. 168 939701 NP_389408.2 CDS ylxW NC_000964.3 1594492 1595187 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16484183; hypothetical protein 1594492..1595187 Bacillus subtilis subsp. subtilis str. 168 936403 NP_389409.2 CDS ylxX NC_000964.3 1595210 1595917 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1595210..1595917 Bacillus subtilis subsp. subtilis str. 168 936107 NP_389410.1 CDS sbp NC_000964.3 1595935 1596300 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1569582, 15849754, 16850406; Product type pm: membrane component; small basic protein 1595935..1596300 Bacillus subtilis subsp. subtilis str. 168 936141 NP_389411.2 CDS ftsA NC_000964.3 1596474 1597796 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15153768, 16159787, 16796675, 17015652; Product type cp: cell process; cell division protein FtsA 1596474..1597796 Bacillus subtilis subsp. subtilis str. 168 936145 NP_389412.2 CDS ftsZ NC_000964.3 1597832 1598980 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1597832..1598980 Bacillus subtilis subsp. subtilis str. 168 935971 NP_389413.1 CDS bpr NC_000964.3 1599283 1603584 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1368833, 15205417, 15375126, 1938892, 2106512; Product type e: enzyme; bacillopeptidase F 1599283..1603584 Bacillus subtilis subsp. subtilis str. 168 939695 NP_389414.1 CDS spoIIGA NC_000964.3 1603779 1604708 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498732, 15849754, 16850406, 7585939, 7729420, 9573195, 9663680; Product type e: enzyme; sporulation sigma-E factor-processing peptidase 1603779..1604708 Bacillus subtilis subsp. subtilis str. 168 939984 NP_389415.2 CDS sigE NC_000964.3 1604771 1605490 D sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation; RNA polymerase sigma-E factor 1604771..1605490 Bacillus subtilis subsp. subtilis str. 168 939683 NP_389416.1 CDS sigG NC_000964.3 1605630 1606412 D sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin; RNA polymerase sigma-G factor 1605630..1606412 Bacillus subtilis subsp. subtilis str. 168 939953 NP_389417.2 CDS ylmA NC_000964.3 1606560 1607354 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pt : transporter; ABC transporter ATP-binding protein 1606560..1607354 Bacillus subtilis subsp. subtilis str. 168 940012 NP_389418.2 CDS ylmB NC_000964.3 1607556 1608836 D catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; N-formyl-4-amino-5-aminomethyl-2- methylpyrimidine deformylase 1607556..1608836 Bacillus subtilis subsp. subtilis str. 168 940116 NP_389419.1 CDS ylmC NC_000964.3 1608919 1609164 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060; hypothetical protein 1608919..1609164 Bacillus subtilis subsp. subtilis str. 168 939682 NP_389420.1 CDS ylmD NC_000964.3 1609327 1610163 D Evidence 4: Homologs of previously reported genes of unknown function; laccase domain protein YlmD 1609327..1610163 Bacillus subtilis subsp. subtilis str. 168 939954 NP_389421.1 CDS ylmE NC_000964.3 1610170 1610862 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14526035; hypothetical protein 1610170..1610862 Bacillus subtilis subsp. subtilis str. 168 940117 NP_389422.2 CDS sepF NC_000964.3 1610865 1611314 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526035, 16420366, 16796675, 18782755; Product type cp: cell process; cell division machinery factor 1610865..1611314 Bacillus subtilis subsp. subtilis str. 168 939952 NP_389423.1 CDS ylmG NC_000964.3 1611321 1611593 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14526035; Product type f: factor; membrane protein 1611321..1611593 Bacillus subtilis subsp. subtilis str. 168 940008 NP_389424.1 CDS ylmH NC_000964.3 1611654 1612427 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10093218, 14526035; Product type f: factor; RNA-binding protein YlmH 1611654..1612427 Bacillus subtilis subsp. subtilis str. 168 940118 NP_389425.1 CDS divIVA NC_000964.3 1612521 1613015 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950914, 14526035, 15165232, 15554965, 16885474; Product type f: factor; septum site-determining protein DivIVA 1612521..1613015 Bacillus subtilis subsp. subtilis str. 168 939972 NP_389426.2 CDS ileS NC_000964.3 1613357 1616122 D IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase; some organisms carry two different copies of this enzyme; isoleucine--tRNA ligase 1613357..1616122 Bacillus subtilis subsp. subtilis str. 168 940119 NP_389427.2 CDS ylyA NC_000964.3 1616267 1616641 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987; hypothetical protein 1616267..1616641 Bacillus subtilis subsp. subtilis str. 168 938068 NP_389428.1 CDS lspA NC_000964.3 1616744 1617208 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1616744..1617208 Bacillus subtilis subsp. subtilis str. 168 938172 NP_389429.3 CDS rluD NC_000964.3 1617210 1618121 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15078091, 15928344, 17188032; Product type e: enzyme; RNA pseudouridine synthase YlyB 1617210..1618121 Bacillus subtilis subsp. subtilis str. 168 939987 NP_389430.1 CDS pyrR NC_000964.3 1618304 1618849 D regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional protein PyrR 1618304..1618849 Bacillus subtilis subsp. subtilis str. 168 938030 NP_389431.2 CDS pyrP NC_000964.3 1619023 1620330 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8206848; Product type t : transporter; uracil permease 1619023..1620330 Bacillus subtilis subsp. subtilis str. 168 936604 NP_389432.2 CDS pyrB NC_000964.3 1620476 1621390 D catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1620476..1621390 Bacillus subtilis subsp. subtilis str. 168 937734 NP_389433.2 CDS pyrC NC_000964.3 1621374 1622660 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16522191, 7516791; Product type e: enzyme; dihydroorotase 1621374..1622660 Bacillus subtilis subsp. subtilis str. 168 937095 NP_389434.1 CDS pyrAA NC_000964.3 1622657 1623751 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl-phosphate synthase pyrimidine-specific small chain 1622657..1623751 Bacillus subtilis subsp. subtilis str. 168 937368 NP_389435.1 CDS carB NC_000964.3 1623736 1626951 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl-phosphate synthase pyrimidine-specific large chain 1623736..1626951 Bacillus subtilis subsp. subtilis str. 168 936608 NP_389436.1 CDS pyrK NC_000964.3 1626948 1627718 D responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase B 1626948..1627718 Bacillus subtilis subsp. subtilis str. 168 936854 NP_389437.1 CDS pyrD NC_000964.3 1627718 1628653 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase B 1627718..1628653 Bacillus subtilis subsp. subtilis str. 168 938008 NP_389438.1 CDS pyrF NC_000964.3 1628622 1629341 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1628622..1629341 Bacillus subtilis subsp. subtilis str. 168 935960 NP_389439.1 CDS pyrE NC_000964.3 1629320 1629970 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1629320..1629970 Bacillus subtilis subsp. subtilis str. 168 936714 NP_389440.1 CDS cysH NC_000964.3 1630382 1631083 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12072441, 16267287, 11004190, 10094622; Product type e: enzyme; phosphoadenosine phosphosulfate reductase 1630382..1631083 Bacillus subtilis subsp. subtilis str. 168 938645 NP_389441.1 CDS cysP NC_000964.3 1631095 1632159 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10784039, 15849754, 16850406, 11004190, 10094622; Product type t : transporter; sulfate permease CysP 1631095..1632159 Bacillus subtilis subsp. subtilis str. 168 935990 NP_389442.1 CDS sat NC_000964.3 1632208 1633356 D ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; sulfate adenylyltransferase 1632208..1633356 Bacillus subtilis subsp. subtilis str. 168 936726 NP_389443.1 CDS cysC NC_000964.3 1633369 1633962 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1332767, 11004190, 10094622; Product type e : enzyme; adenylyl-sulfate kinase 1633369..1633962 Bacillus subtilis subsp. subtilis str. 168 937102 NP_389444.1 CDS sumT NC_000964.3 1634061 1634834 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1906874, 11004190, 10094622; Product type e : enzyme; uroporphyrinogen-iii C-methyltransferase 1634061..1634834 Bacillus subtilis subsp. subtilis str. 168 936712 NP_389445.1 CDS sirB NC_000964.3 1634837 1635622 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme; sirohydrochlorin ferrochelatase 1634837..1635622 Bacillus subtilis subsp. subtilis str. 168 936218 NP_389446.1 CDS sirC NC_000964.3 1635603 1636091 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme; precorrin-2 dehydrogenase 1635603..1636091 Bacillus subtilis subsp. subtilis str. 168 938048 NP_389447.1 CDS yloA NC_000964.3 1636131 1637849 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11238985, 17586671; Product type pf: factor; hypothetical protein complement(1636131..1637849) Bacillus subtilis subsp. subtilis str. 168 936878 NP_389448.1 CDS yloB NC_000964.3 1637965 1640637 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12161109; Product type t: transporter; calcium-transporting ATPase 1637965..1640637 Bacillus subtilis subsp. subtilis str. 168 936954 NP_389449.1 CDS yloC NC_000964.3 1640720 1641595 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1640720..1641595 Bacillus subtilis subsp. subtilis str. 168 936454 NP_570902.1 CDS ylzA NC_000964.3 1641672 1641941 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1641672..1641941 Bacillus subtilis subsp. subtilis str. 168 937956 NP_389450.2 CDS gmk NC_000964.3 1641949 1642563 D Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1641949..1642563 Bacillus subtilis subsp. subtilis str. 168 938821 NP_389451.1 CDS rpoZ NC_000964.3 1642567 1642770 D Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1642567..1642770 Bacillus subtilis subsp. subtilis str. 168 936419 NP_389452.1 CDS coaBC NC_000964.3 1642851 1644071 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11278255, 11358972, 12140293, 14686929, 15530362; Product type e: enzyme; coenzyme A biosynthesis bifunctional protein CoaBC 1642851..1644071 Bacillus subtilis subsp. subtilis str. 168 938487 NP_389453.1 CDS priA NC_000964.3 1644068 1646485 D binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosomal protein N' 1644068..1646485 Bacillus subtilis subsp. subtilis str. 168 938122 NP_389454.1 CDS def NC_000964.3 1646512 1646994 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1646512..1646994 Bacillus subtilis subsp. subtilis str. 168 938819 NP_389455.1 CDS fmt NC_000964.3 1646999 1647952 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10858337, 9843487; Product type e: enzyme; methionyl-tRNA formyltransferase 1646999..1647952 Bacillus subtilis subsp. subtilis str. 168 936571 NP_389456.1 CDS rsmB NC_000964.3 1647939 1649282 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14656444; Product type e: enzyme; ribosomal RNA small subunit methyltransferase B 1647939..1649282 Bacillus subtilis subsp. subtilis str. 168 938106 NP_389457.1 CDS yloN NC_000964.3 1649286 1650377 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; dual-specificity RNA methyltransferase RlmN 1649286..1650377 Bacillus subtilis subsp. subtilis str. 168 936310 NP_389458.1 CDS prpC NC_000964.3 1650384 1651148 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 10986276; Product type e: enzyme; protein phosphatase PrpC 1650384..1651148 Bacillus subtilis subsp. subtilis str. 168 935931 NP_389459.1 CDS prkC NC_000964.3 1651142 1653088 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 18984160, 10986276; Product type e: enzyme; serine/threonine protein kinase 1651142..1653088 Bacillus subtilis subsp. subtilis str. 168 936132 NP_389460.1 CDS yloQ NC_000964.3 1653103 1653999 D EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome biogenesis GTPase RsgA 1653103..1653999 Bacillus subtilis subsp. subtilis str. 168 938451 NP_389461.1 CDS rpe NC_000964.3 1654004 1654657 D catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1654004..1654657 Bacillus subtilis subsp. subtilis str. 168 936393 NP_389462.1 CDS thiN NC_000964.3 1654730 1655374 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15150256, 16291685; Product type e: enzyme; thiamine pyrophosphokinase 1654730..1655374 Bacillus subtilis subsp. subtilis str. 168 937714 NP_389463.1 CDS spoVM NC_000964.3 1655446 1655526 D involved in the production of the spore cortex and coat; stage V sporulation protein M 1655446..1655526 Bacillus subtilis subsp. subtilis str. 168 937168 NP_389464.1 CDS rpmB NC_000964.3 1655599 1655787 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(1655599..1655787) Bacillus subtilis subsp. subtilis str. 168 938067 NP_389465.1 CDS yloU NC_000964.3 1656064 1656426 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1656064..1656426 Bacillus subtilis subsp. subtilis str. 168 937855 NP_389466.1 CDS yloV NC_000964.3 1656442 1658103 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16647083; Product type pe : enzyme; hypothetical protein 1656442..1658103 Bacillus subtilis subsp. subtilis str. 168 937917 NP_389467.1 CDS sdaAB NC_000964.3 1658242 1658904 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 8385012, 9244285; Product type e : enzyme; L-serine dehydratase, beta chain 1658242..1658904 Bacillus subtilis subsp. subtilis str. 168 935964 NP_389468.1 CDS sdaAA NC_000964.3 1658930 1659832 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 2504697; Product type e: enzyme; L-serine dehydratase, alpha chain 1658930..1659832 Bacillus subtilis subsp. subtilis str. 168 937109 NP_389469.1 CDS recG NC_000964.3 1659810 1661858 D catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1659810..1661858 Bacillus subtilis subsp. subtilis str. 168 936730 NP_389470.1 CDS ylpC NC_000964.3 1661967 1662533 D negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; transcription factor FapR 1661967..1662533 Bacillus subtilis subsp. subtilis str. 168 936595 NP_389471.1 CDS plsX NC_000964.3 1662547 1663548 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; phosphate acyltransferase 1662547..1663548 Bacillus subtilis subsp. subtilis str. 168 938066 NP_389472.1 CDS fabD NC_000964.3 1663567 1664520 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14586097; Product type e: enzyme; malonyl CoA-acyl carrier protein transacylase 1663567..1664520 Bacillus subtilis subsp. subtilis str. 168 938488 NP_389473.1 CDS fabG NC_000964.3 1664513 1665253 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12655455, 12682299, 8759840; Product type e: enzyme; 3-oxoacyl-[acyl-carrier-protein] reductase FabG 1664513..1665253 Bacillus subtilis subsp. subtilis str. 168 938113 NP_389474.1 CDS acpP NC_000964.3 1665337 1665570 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1665337..1665570 Bacillus subtilis subsp. subtilis str. 168 938486 NP_389475.1 CDS rnc NC_000964.3 1665710 1666459 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease 3 1665710..1666459 Bacillus subtilis subsp. subtilis str. 168 936169 NP_389476.2 CDS smc NC_000964.3 1666560 1670120 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137, 15987505, 16272394, 9701812; Product type e : enzyme; chromosome partition protein Smc 1666560..1670120 Bacillus subtilis subsp. subtilis str. 168 938085 NP_389477.1 CDS ftsY NC_000964.3 1670140 1671129 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15995216, 16705751, 11021934, 11123669, 11166993; Product type rc : receptor; signal recognition particle receptor FtsY 1670140..1671129 Bacillus subtilis subsp. subtilis str. 168 936921 NP_389478.1 CDS ylqB NC_000964.3 1671166 1671651 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein complement(1671166..1671651) Bacillus subtilis subsp. subtilis str. 168 938179 NP_389479.1 CDS ylxM NC_000964.3 1671828 1672160 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11274114; hypothetical protein 1671828..1672160 Bacillus subtilis subsp. subtilis str. 168 937995 NP_389480.1 CDS ffh NC_000964.3 1672174 1673514 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 10658653, 11123669, 7511896, 8662730, 10222262, 10224127; Product type cp: cell process; signal recognition particle protein 1672174..1673514 Bacillus subtilis subsp. subtilis str. 168 937104 NP_389481.1 CDS rpsP NC_000964.3 1673620 1673892 D binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1673620..1673892 Bacillus subtilis subsp. subtilis str. 168 938059 NP_389482.1 CDS ylqC NC_000964.3 1673892 1674137 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1673892..1674137 Bacillus subtilis subsp. subtilis str. 168 936821 NP_389483.1 CDS ylqD NC_000964.3 1674259 1674645 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1674259..1674645 Bacillus subtilis subsp. subtilis str. 168 937226 NP_389484.1 CDS rimM NC_000964.3 1674650 1675174 D Essential for efficient processing of 16S rRNA; ribosome maturation factor RimM 1674650..1675174 Bacillus subtilis subsp. subtilis str. 168 935999 NP_389485.1 CDS trmD NC_000964.3 1675171 1675902 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1675171..1675902 Bacillus subtilis subsp. subtilis str. 168 936650 NP_389486.1 CDS rplS NC_000964.3 1676033 1676389 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1676033..1676389 Bacillus subtilis subsp. subtilis str. 168 937598 NP_389487.1 CDS rbgA NC_000964.3 1676532 1677380 D essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosome biogenesis GTPase A 1676532..1677380 Bacillus subtilis subsp. subtilis str. 168 940134 NP_389488.1 CDS rnhB NC_000964.3 1677451 1678218 D RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1677451..1678218 Bacillus subtilis subsp. subtilis str. 168 940133 NP_389489.1 CDS ylqG NC_000964.3 1678250 1679980 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1678250..1679980 Bacillus subtilis subsp. subtilis str. 168 936698 NP_389490.1 CDS ylqH NC_000964.3 1679977 1680258 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1679977..1680258 Bacillus subtilis subsp. subtilis str. 168 938163 NP_389491.1 CDS sucC NC_000964.3 1680431 1681588 D catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA ligase [ADP-forming] subunit beta 1680431..1681588 Bacillus subtilis subsp. subtilis str. 168 938521 NP_389492.1 CDS sucD NC_000964.3 1681617 1682519 D Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA ligase [ADP-forming] subunit alpha 1681617..1682519 Bacillus subtilis subsp. subtilis str. 168 937797 NP_389493.1 CDS dprA NC_000964.3 1682580 1683473 D Evidence 2b: Function of strongly homologous gene; PubMedId: 16014871, 16978360, 17803906, 18045469, 7768823; Product type f: factor; protein smf 1682580..1683473 Bacillus subtilis subsp. subtilis str. 168 940135 NP_389494.1 CDS topA NC_000964.3 1683661 1685736 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase 1 1683661..1685736 Bacillus subtilis subsp. subtilis str. 168 937982 NP_389495.1 CDS gid NC_000964.3 1685812 1687119 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO 1685812..1687119 Bacillus subtilis subsp. subtilis str. 168 938816 NP_389496.1 CDS xerC NC_000964.3 1687187 1688101 D site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; tyrosine recombinase XerC 1687187..1688101 Bacillus subtilis subsp. subtilis str. 168 938003 NP_389497.1 CDS clpQ NC_000964.3 1688114 1688659 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease subunit ClpQ 1688114..1688659 Bacillus subtilis subsp. subtilis str. 168 938111 NP_389498.1 CDS hslU NC_000964.3 1688676 1690079 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATPase subunit ClpY 1688676..1690079 Bacillus subtilis subsp. subtilis str. 168 936301 NP_389499.1 CDS codY NC_000964.3 1690119 1690898 D CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; GTP-sensing transcriptional pleiotropic repressor CodY 1690119..1690898 Bacillus subtilis subsp. subtilis str. 168 936491 NP_389500.1 CDS flgB NC_000964.3 1691278 1691667 D with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1691278..1691667 Bacillus subtilis subsp. subtilis str. 168 938149 NP_389501.1 CDS flgC NC_000964.3 1691667 1692119 D with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgC 1691667..1692119 Bacillus subtilis subsp. subtilis str. 168 938646 NP_389502.1 CDS fliE NC_000964.3 1692130 1692450 D forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body complex protein FliE 1692130..1692450 Bacillus subtilis subsp. subtilis str. 168 939470 NP_389503.1 CDS fliF NC_000964.3 1692496 1694106 D the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar M-ring protein 1692496..1694106 Bacillus subtilis subsp. subtilis str. 168 936677 NP_389504.1 CDS fliG NC_000964.3 1694119 1695135 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliG 1694119..1695135 Bacillus subtilis subsp. subtilis str. 168 937577 NP_389505.2 CDS fliH NC_000964.3 1695254 1695880 D binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein FliH 1695254..1695880 Bacillus subtilis subsp. subtilis str. 168 938124 NP_389506.2 CDS fliI NC_000964.3 1695877 1697193 D involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1695877..1697193 Bacillus subtilis subsp. subtilis str. 168 940136 NP_389507.1 CDS fliJ NC_000964.3 1697196 1697639 D rod/hook and filament chaperone; flagellar FliJ protein 1697196..1697639 Bacillus subtilis subsp. subtilis str. 168 940137 NP_389508.2 CDS ylxF NC_000964.3 1697651 1698265 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; FlaA locus 22.9 kDa protein 1697651..1698265 Bacillus subtilis subsp. subtilis str. 168 940140 NP_389509.2 CDS fliK NC_000964.3 1698278 1699741 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16630628, 16949608; Product type f: factor; flagellar hook-length control protein 1698278..1699741 Bacillus subtilis subsp. subtilis str. 168 937494 NP_389510.1 CDS flgD NC_000964.3 1699738 1700160 D acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; FlaA locus hypothetical protein YlxG 1699738..1700160 Bacillus subtilis subsp. subtilis str. 168 936501 NP_389511.2 CDS flgG NC_000964.3 1700182 1700976 D makes up the distal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgG 1700182..1700976 Bacillus subtilis subsp. subtilis str. 168 936497 YP_003097728.1 CDS ylzI NC_000964.3 1701016 1701231 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 1701016..1701231 Bacillus subtilis subsp. subtilis str. 168 8303013 NP_389512.1 CDS fliL NC_000964.3 1701228 1701650 D interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar protein FliL 1701228..1701650 Bacillus subtilis subsp. subtilis str. 168 937103 NP_389513.1 CDS fliM NC_000964.3 1701684 1702682 D with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1701684..1702682 Bacillus subtilis subsp. subtilis str. 168 939518 NP_389514.1 CDS fliY NC_000964.3 1702672 1703808 D One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch phosphatase FliY 1702672..1703808 Bacillus subtilis subsp. subtilis str. 168 936421 NP_389515.1 CDS cheY NC_000964.3 1703834 1704196 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 12864845, 12920116, 14749334; Product type r: regulator; chemotaxis protein CheY 1703834..1704196 Bacillus subtilis subsp. subtilis str. 168 940120 NP_389516.1 CDS fliZ NC_000964.3 1704211 1704870 D possible structural component of the flagellum that anchors the rod to the membrane; flagellar biosynthetic protein FliZ 1704211..1704870 Bacillus subtilis subsp. subtilis str. 168 936796 NP_389517.1 CDS fliP NC_000964.3 1704863 1705528 D FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliP 1704863..1705528 Bacillus subtilis subsp. subtilis str. 168 940095 NP_389518.1 CDS fliQ NC_000964.3 1705543 1705812 D with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliQ 1705543..1705812 Bacillus subtilis subsp. subtilis str. 168 939623 NP_389519.2 CDS fliR NC_000964.3 1705820 1706599 D FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliR 1705820..1706599 Bacillus subtilis subsp. subtilis str. 168 940130 NP_389520.1 CDS flhB NC_000964.3 1706599 1707681 D membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthetic protein FlhB 1706599..1707681 Bacillus subtilis subsp. subtilis str. 168 940128 NP_389521.2 CDS flhA NC_000964.3 1707714 1709747 D membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1707714..1709747 Bacillus subtilis subsp. subtilis str. 168 940029 NP_389522.1 CDS flhF NC_000964.3 1709747 1710847 D positive regulator of class III flagellar genes; flagellar biosynthesis protein FlhF 1709747..1710847 Bacillus subtilis subsp. subtilis str. 168 940021 NP_389523.1 CDS ylxH NC_000964.3 1710838 1711734 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15361076; Product type f: factor; flagellum site-determining protein YlxH 1710838..1711734 Bacillus subtilis subsp. subtilis str. 168 940123 NP_389524.2 CDS cheB NC_000964.3 1711736 1712809 D regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis response regulator protein-glutamate methylesterase 1711736..1712809 Bacillus subtilis subsp. subtilis str. 168 940124 NP_389525.2 CDS cheA NC_000964.3 1712815 1714833 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12094812, 12864845, 12920116, 15451661, 16045621; Product type rc: receptor; chemotaxis protein CheA 1712815..1714833 Bacillus subtilis subsp. subtilis str. 168 939600 NP_389526.1 CDS cheW NC_000964.3 1714855 1715325 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12864845, 15451661, 1624415, 8169223, 8169224; Product type r: regulator; chemotaxis protein CheW 1714855..1715325 Bacillus subtilis subsp. subtilis str. 168 939957 NP_389527.1 CDS cheC NC_000964.3 1715344 1715973 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12920116, 14749334, 14993307, 15546616, 16469702; Product type cp: cell process; Chey-P phosphatase CheC 1715344..1715973 Bacillus subtilis subsp. subtilis str. 168 939621 NP_389528.1 CDS cheD NC_000964.3 1715970 1716470 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15546616, 16469702; Product type cp: cell process; chemoreceptor glutamine deamidase CheD 1715970..1716470 Bacillus subtilis subsp. subtilis str. 168 939959 NP_389529.1 CDS sigD NC_000964.3 1716493 1717257 D expressed in late exponential phase; controls the expression of genes coding cell surface proteins involved in chemotaxis, flagellar assembly, and autolysis; RNA polymerase sigma-D factor 1716493..1717257 Bacillus subtilis subsp. subtilis str. 168 938482 NP_389530.1 CDS ylxL NC_000964.3 1717286 1717789 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 15175317; Product type r: regulator; swarming motility protein SwrB 1717286..1717789 Bacillus subtilis subsp. subtilis str. 168 939618 NP_389531.1 CDS rpsB NC_000964.3 1717933 1718673 D one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1717933..1718673 Bacillus subtilis subsp. subtilis str. 168 939599 NP_389532.1 CDS tsf NC_000964.3 1718775 1719656 D EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1718775..1719656 Bacillus subtilis subsp. subtilis str. 168 939601 NP_389533.2 CDS pyrH NC_000964.3 1719802 1720524 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1719802..1720524 Bacillus subtilis subsp. subtilis str. 168 939602 NP_389534.1 CDS frr NC_000964.3 1720526 1721083 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome-recycling factor 1720526..1721083 Bacillus subtilis subsp. subtilis str. 168 939605 NP_389535.1 CDS uppS NC_000964.3 1721214 1721996 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1721214..1721996 Bacillus subtilis subsp. subtilis str. 168 939640 NP_389536.1 CDS cdsA NC_000964.3 1722000 1722809 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406; Product type e : enzyme; phosphatidate cytidylyltransferase 1722000..1722809 Bacillus subtilis subsp. subtilis str. 168 939607 NP_389537.2 CDS dxr NC_000964.3 1722871 1724022 D catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1722871..1724022 Bacillus subtilis subsp. subtilis str. 168 939636 NP_389538.1 CDS rseP NC_000964.3 1724029 1725297 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127, 15496982, 15520285, 16014871, 16899079; Product type e: enzyme; zinc metalloprotease RasP 1724029..1725297 Bacillus subtilis subsp. subtilis str. 168 939612 NP_389539.1 CDS proS NC_000964.3 1725330 1727024 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); proline--tRNA ligase 1725330..1727024 Bacillus subtilis subsp. subtilis str. 168 939617 NP_389540.1 CDS polC NC_000964.3 1727133 1731446 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC-type 1727133..1731446 Bacillus subtilis subsp. subtilis str. 168 939620 NP_389541.1 CDS ylxS NC_000964.3 1731776 1732246 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; ribosome maturation factor RimP 1731776..1732246 Bacillus subtilis subsp. subtilis str. 168 939625 NP_389542.1 CDS nusA NC_000964.3 1732281 1733396 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription termination/antitermination protein NusA 1732281..1733396 Bacillus subtilis subsp. subtilis str. 168 939628 NP_389543.1 CDS ylxR NC_000964.3 1733410 1733685 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11679764, 12682299; Product type pf: factor; hypothetical protein 1733410..1733685 Bacillus subtilis subsp. subtilis str. 168 939653 NP_389544.1 CDS ylxQ NC_000964.3 1733687 1733989 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15130481, 15361074; Product type f : factor; ribosomal protein YlxQ 1733687..1733989 Bacillus subtilis subsp. subtilis str. 168 939626 NP_389545.1 CDS infB NC_000964.3 1734009 1736159 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1734009..1736159 Bacillus subtilis subsp. subtilis str. 168 939630 NP_389546.1 CDS ylxP NC_000964.3 1736156 1736434 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1736156..1736434 Bacillus subtilis subsp. subtilis str. 168 939641 NP_389547.1 CDS rbfA NC_000964.3 1736451 1736804 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1736451..1736804 Bacillus subtilis subsp. subtilis str. 168 939635 NP_389548.1 CDS truB NC_000964.3 1736886 1737815 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1736886..1737815 Bacillus subtilis subsp. subtilis str. 168 939638 NP_389549.1 CDS ribC NC_000964.3 1737834 1738784 D catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; riboflavin biosynthesis protein RibC 1737834..1738784 Bacillus subtilis subsp. subtilis str. 168 938110 NP_389550.1 CDS rpsO NC_000964.3 1738941 1739210 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1738941..1739210 Bacillus subtilis subsp. subtilis str. 168 938814 NP_389551.1 CDS pnpA NC_000964.3 1739383 1741500 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572137, 15805522, 8636041, 8825779, 9179491; Product type e: enzyme; polyribonucleotide nucleotidyltransferase 1739383..1741500 Bacillus subtilis subsp. subtilis str. 168 939646 NP_389552.1 CDS ylxY NC_000964.3 1741618 1742577 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227; Product type pe : enzyme; hypothetical protein 1741618..1742577 Bacillus subtilis subsp. subtilis str. 168 939649 NP_389553.2 CDS mlpA NC_000964.3 1742617 1743846 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10666719, 10974125; Product type e: enzyme; zinc protease YmxG 1742617..1743846 Bacillus subtilis subsp. subtilis str. 168 938456 NP_389554.1 CDS ymxH NC_000964.3 1743924 1744181 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1743924..1744181 Bacillus subtilis subsp. subtilis str. 168 939648 NP_389555.1 CDS spoVFA NC_000964.3 1744367 1745260 D catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance; dipicolinate synthase subunit A 1744367..1745260 Bacillus subtilis subsp. subtilis str. 168 939652 NP_389556.1 CDS spoVFB NC_000964.3 1745263 1745865 D involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme; dipicolinate synthase subunit B 1745263..1745865 Bacillus subtilis subsp. subtilis str. 168 939660 NP_389557.1 CDS asd NC_000964.3 1745991 1747031 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1745991..1747031 Bacillus subtilis subsp. subtilis str. 168 939654 NP_389558.2 CDS dapG NC_000964.3 1747123 1748337 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; aspartokinase 1 1747123..1748337 Bacillus subtilis subsp. subtilis str. 168 936710 NP_389559.1 CDS dapA NC_000964.3 1748368 1749240 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; 4-hydroxy-tetrahydrodipicolinate synthase 1748368..1749240 Bacillus subtilis subsp. subtilis str. 168 939657 NP_389560.2 CDS rnjB NC_000964.3 1749418 1751085 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15831787, 18713320; Product type e: enzyme; ribonuclease J 2 1749418..1751085 Bacillus subtilis subsp. subtilis str. 168 938463 NP_389561.3 CDS tepA NC_000964.3 1751201 1751938 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 15189290; Product type f: factor; translocation-enhancing protein TepA 1751201..1751938 Bacillus subtilis subsp. subtilis str. 168 936370 YP_003097729.1 CDS ylzJ NC_000964.3 1751935 1752147 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1751935..1752147 Bacillus subtilis subsp. subtilis str. 168 8303181 NP_389562.2 CDS spoIIIE NC_000964.3 1752272 1754641 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11062134, 11778051, 12618465, 16430687, 17139259, 17322320, 18160039; Product type cp: cell process; spore DNA translocase 1752272..1754641 Bacillus subtilis subsp. subtilis str. 168 936503 NP_389563.1 CDS ymfC NC_000964.3 1754785 1755510 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 1754785..1755510 Bacillus subtilis subsp. subtilis str. 168 940138 NP_389564.2 CDS ymfD NC_000964.3 1755649 1756857 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; bacillibactin exporter 1755649..1756857 Bacillus subtilis subsp. subtilis str. 168 939662 NP_389566.2 CDS ymfF NC_000964.3 1757037 1758317 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; inactive metalloprotease YmfF 1757037..1758317 Bacillus subtilis subsp. subtilis str. 168 940141 NP_389568.2 CDS ymfH NC_000964.3 1758314 1759600 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; zinc protease YmfH 1758314..1759600 Bacillus subtilis subsp. subtilis str. 168 939665 NP_389569.2 CDS fabG NC_000964.3 1759655 1760383 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 1759655..1760383 Bacillus subtilis subsp. subtilis str. 168 939588 NP_389570.1 CDS ymfJ NC_000964.3 1760464 1760721 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1760464..1760721 Bacillus subtilis subsp. subtilis str. 168 939670 NP_389573.3 CDS ymfM NC_000964.3 1761707 1762573 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12682299; membrane protein 1761707..1762573 Bacillus subtilis subsp. subtilis str. 168 939591 NP_389574.2 CDS pgsA NC_000964.3 1762623 1763204 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15743965, 15849754, 16514141, 16850406; Product type e: enzyme; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1762623..1763204 Bacillus subtilis subsp. subtilis str. 168 939675 NP_389575.2 CDS cinA NC_000964.3 1763222 1764472 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438773, 11703670; Product type r : regulator; competence-damage inducible protein 1763222..1764472 Bacillus subtilis subsp. subtilis str. 168 939464 NP_389576.2 CDS recA NC_000964.3 1764645 1765691 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase RecA 1764645..1765691 Bacillus subtilis subsp. subtilis str. 168 939497 NP_389577.1 CDS pbpX NC_000964.3 1765859 1767034 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762009, 15758244; Product type e: enzyme; penicillin-binding protein PbpX 1765859..1767034 Bacillus subtilis subsp. subtilis str. 168 939677 NP_389578.1 CDS ymdA NC_000964.3 1767310 1768872 D protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; ribonuclease Y 1767310..1768872 Bacillus subtilis subsp. subtilis str. 168 939680 NP_389579.2 CDS ymdB NC_000964.3 1768941 1769735 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1768941..1769735 Bacillus subtilis subsp. subtilis str. 168 939441 NP_389580.1 CDS spoVS NC_000964.3 1769935 1770195 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16428420, 7559352; Product type r: regulator; stage V sporulation protein S 1769935..1770195 Bacillus subtilis subsp. subtilis str. 168 939460 NP_389581.1 CDS tdh NC_000964.3 1770461 1771504 D converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 1770461..1771504 Bacillus subtilis subsp. subtilis str. 168 939462 NP_389582.1 CDS kbl NC_000964.3 1771517 1772695 D catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 1771517..1772695 Bacillus subtilis subsp. subtilis str. 168 939651 NP_389583.1 CDS ymcB NC_000964.3 1772843 1774372 D catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase MiaB 1772843..1774372 Bacillus subtilis subsp. subtilis str. 168 939451 NP_389584.1 CDS ymcA NC_000964.3 1774374 1774805 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000; Product type r: regulator; hypothetical protein 1774374..1774805 Bacillus subtilis subsp. subtilis str. 168 939581 NP_389585.1 CDS cotE NC_000964.3 1775067 1775612 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14563859, 14973022, 17172339; Product type cp: cell process; spore coat protein E 1775067..1775612 Bacillus subtilis subsp. subtilis str. 168 939508 NP_389586.2 CDS mutS NC_000964.3 1775745 1778321 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1775745..1778321 Bacillus subtilis subsp. subtilis str. 168 939501 NP_389587.1 CDS mutL NC_000964.3 1778337 1780220 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein MutL 1778337..1780220 Bacillus subtilis subsp. subtilis str. 168 939455 YP_054578.1 CDS ymzD NC_000964.3 1780618 1781073 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1780618..1781073) Bacillus subtilis subsp. subtilis str. 168 2914256 NP_389588.1 CDS ymcC NC_000964.3 1781228 1781785 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(1781228..1781785) Bacillus subtilis subsp. subtilis str. 168 939511 NP_389589.1 CDS pksA NC_000964.3 1781906 1782523 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 1781906..1782523 Bacillus subtilis subsp. subtilis str. 168 939593 NP_389590.1 CDS pksB NC_000964.3 1782713 1783390 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polyketide biosynthesis zinc-dependent hydrolase 1782713..1783390 Bacillus subtilis subsp. subtilis str. 168 939445 NP_389591.1 CDS pksC NC_000964.3 1783763 1784629 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme; polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC 1783763..1784629 Bacillus subtilis subsp. subtilis str. 168 939504 NP_389592.2 CDS pksD NC_000964.3 1785133 1786107 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme; polyketide biosynthesis acyltransferase homolog PksD 1785133..1786107 Bacillus subtilis subsp. subtilis str. 168 939463 NP_389593.3 CDS pksE NC_000964.3 1786104 1788407 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme; polyketide biosynthesis protein PksE 1786104..1788407 Bacillus subtilis subsp. subtilis str. 168 939997 NP_570904.1 CDS acpK NC_000964.3 1788469 1788717 D Acyl carrier proteins are involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; this ACP may be involved in the biosynthesis of lipopeptide antibiotics; polyketide biosynthesis acyl-carrier-protein AcpK 1788469..1788717 Bacillus subtilis subsp. subtilis str. 168 937952 NP_389594.2 CDS pksF NC_000964.3 1788695 1789942 D involved in polyketide production; polyketide biosynthesis malonyl-ACP decarboxylase PksF 1788695..1789942 Bacillus subtilis subsp. subtilis str. 168 939500 NP_389595.2 CDS pksG NC_000964.3 1789943 1791205 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme; polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG 1789943..1791205 Bacillus subtilis subsp. subtilis str. 168 940121 NP_389596.1 CDS pksH NC_000964.3 1791193 1791972 D involved in polyketide synthesis; polyketide biosynthesis enoyl-CoA hydratase PksH 1791193..1791972 Bacillus subtilis subsp. subtilis str. 168 940033 NP_389597.2 CDS pksI NC_000964.3 1792012 1792761 D involved in polyketide production; polyketide biosynthesis enoyl-CoA isomerase PksI 1792012..1792761 Bacillus subtilis subsp. subtilis str. 168 940096 NP_389598.3 CDS pksJ NC_000964.3 1792806 1807937 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16460000, 16707694; Product type e: enzyme; polyketide synthase PksJ 1792806..1807937 Bacillus subtilis subsp. subtilis str. 168 940043 NP_389600.3 CDS pksL NC_000964.3 1807921 1821537 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561, 17042494; Product type e: enzyme; polyketide synthase PksL 1807921..1821537 Bacillus subtilis subsp. subtilis str. 168 940032 NP_389601.3 CDS pksM NC_000964.3 1821553 1834341 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15480790; Product type e: enzyme; polyketide synthase PksM 1821553..1834341 Bacillus subtilis subsp. subtilis str. 168 940026 NP_389602.3 CDS pksN NC_000964.3 1834409 1850875 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16460000; Product type e: enzyme; polyketide synthase PksN 1834409..1850875 Bacillus subtilis subsp. subtilis str. 168 940054 NP_389604.2 CDS pksR NC_000964.3 1850890 1858521 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 15480790; Product type e: enzyme; polyketide synthase PksR 1850890..1858521 Bacillus subtilis subsp. subtilis str. 168 940036 NP_389605.2 CDS pksS NC_000964.3 1858566 1859783 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17482575; Product type e: enzyme; polyketide biosynthesis cytochrome P450 PksS complement(1858566..1859783) Bacillus subtilis subsp. subtilis str. 168 940046 NP_389606.3 CDS ymzB NC_000964.3 1860014 1860370 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1860014..1860370) Bacillus subtilis subsp. subtilis str. 168 940041 NP_389607.2 CDS ymaE NC_000964.3 1860449 1861273 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(1860449..1861273) Bacillus subtilis subsp. subtilis str. 168 940045 NP_389608.1 CDS aprX NC_000964.3 1861384 1862712 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589719, 16267290, 17884659; Product type e: enzyme; serine protease AprX complement(1861384..1862712) Bacillus subtilis subsp. subtilis str. 168 940056 NP_389609.1 CDS ymaC NC_000964.3 1863448 1864155 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type h : extrachromosomal origin; hypothetical protein 1863448..1864155 Bacillus subtilis subsp. subtilis str. 168 940071 NP_389610.1 CDS ymaD NC_000964.3 1864225 1864677 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 1864225..1864677 Bacillus subtilis subsp. subtilis str. 168 940058 NP_389611.1 CDS ebrB NC_000964.3 1864691 1865044 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 15849754, 16750162, 16850406; Product type t: transporter; multidrug resistance protein EbrB complement(1864691..1865044) Bacillus subtilis subsp. subtilis str. 168 940051 NP_389612.1 CDS ebrA NC_000964.3 1865058 1865375 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 11104814, 17516673; Product type t: transporter; multidrug resistance protein EbrA complement(1865058..1865375) Bacillus subtilis subsp. subtilis str. 168 940059 NP_389613.2 CDS ymaG NC_000964.3 1865512 1865787 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1865512..1865787) Bacillus subtilis subsp. subtilis str. 168 940062 NP_389614.2 CDS ymaF NC_000964.3 1865876 1866289 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1865876..1866289 Bacillus subtilis subsp. subtilis str. 168 940060 NP_389615.2 CDS miaA NC_000964.3 1866389 1867333 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA dimethylallyltransferase 1866389..1867333 Bacillus subtilis subsp. subtilis str. 168 940067 NP_389616.1 CDS hfq NC_000964.3 1867373 1867594 D Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1867373..1867594 Bacillus subtilis subsp. subtilis str. 168 940073 NP_389617.1 CDS ymzC NC_000964.3 1867790 1868062 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1867790..1868062 Bacillus subtilis subsp. subtilis str. 168 940085 NP_389618.1 CDS ymzA NC_000964.3 1868144 1868374 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1868144..1868374 Bacillus subtilis subsp. subtilis str. 168 940080 NP_389619.1 CDS nrdI NC_000964.3 1868617 1869009 D in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein NrdI 1868617..1869009 Bacillus subtilis subsp. subtilis str. 168 940075 NP_389620.1 CDS nrdE NC_000964.3 1868969 1871071 D Catalyzes the rate-limiting step in dNTP synthesis; ribonucleoside-diphosphate reductase subunit alpha 1868969..1871071 Bacillus subtilis subsp. subtilis str. 168 940091 NP_389621.1 CDS nrdF NC_000964.3 1871089 1872078 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleoside-diphosphate reductase subunit beta 1871089..1872078 Bacillus subtilis subsp. subtilis str. 168 940076 NP_389622.1 CDS ymaB NC_000964.3 1872128 1872748 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885274; Product type pe : enzyme; hypothetical protein 1872128..1872748 Bacillus subtilis subsp. subtilis str. 168 939453 NP_389623.2 CDS cwlC NC_000964.3 1872812 1873579 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10945275, 10974124, 11375403, 16042392; Product type e: enzyme; sporulation-specific N-acetylmuramoyl-L-alanine amidase complement(1872812..1873579) Bacillus subtilis subsp. subtilis str. 168 940088 NP_389624.2 CDS spoVK NC_000964.3 1874203 1875171 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8464402; Product type cp: cell process; stage V sporulation protein K 1874203..1875171 Bacillus subtilis subsp. subtilis str. 168 940089 NP_389625.2 CDS ynbA NC_000964.3 1875304 1876566 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; GTPase HflX 1875304..1876566 Bacillus subtilis subsp. subtilis str. 168 938169 NP_389626.2 CDS ynbB NC_000964.3 1876584 1877849 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1876584..1877849 Bacillus subtilis subsp. subtilis str. 168 940047 NP_389627.1 CDS glnR NC_000964.3 1877959 1878366 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12374841, 16547045, 16885465, 9287005; Product type r: regulator; MerR family transcriptional regulator 1877959..1878366 Bacillus subtilis subsp. subtilis str. 168 940070 NP_389628.1 CDS glnA NC_000964.3 1878425 1879759 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719184, 12142436, 13737, 16055443, 16885465; Product type e: enzyme; glutamine synthetase 1878425..1879759 Bacillus subtilis subsp. subtilis str. 168 940020 NP_389629.1 CDS ynxB NC_000964.3 1880087 1880377 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 1880087..1880377 Bacillus subtilis subsp. subtilis str. 168 939610 NP_389630.1 CDS ynzF NC_000964.3 1880623 1880967 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1880623..1880967 Bacillus subtilis subsp. subtilis str. 168 939642 NP_389631.1 CDS ynzG NC_000964.3 1881098 1881349 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1881098..1881349 Bacillus subtilis subsp. subtilis str. 168 938126 NP_389632.2 CDS ynaB NC_000964.3 1881536 1881970 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1881536..1881970 Bacillus subtilis subsp. subtilis str. 168 940017 NP_389633.1 CDS ynaC NC_000964.3 1882040 1882831 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1882040..1882831 Bacillus subtilis subsp. subtilis str. 168 936647 NP_389634.1 CDS ynaD NC_000964.3 1883166 1883678 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YnaD 1883166..1883678 Bacillus subtilis subsp. subtilis str. 168 936242 NP_389635.1 CDS ynaE NC_000964.3 1884238 1884879 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1884238..1884879 Bacillus subtilis subsp. subtilis str. 168 936948 NP_389636.1 CDS ynaF NC_000964.3 1884968 1885321 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1884968..1885321 Bacillus subtilis subsp. subtilis str. 168 938101 NP_389637.1 CDS ynaG NC_000964.3 1885365 1885640 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1885365..1885640 Bacillus subtilis subsp. subtilis str. 168 940014 YP_003097730.1 CDS ynzI NC_000964.3 1885753 1885917 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1885753..1885917 Bacillus subtilis subsp. subtilis str. 168 8303140 NP_389638.3 CDS ynaI NC_000964.3 1886057 1886527 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1886057..1886527 Bacillus subtilis subsp. subtilis str. 168 940011 NP_389639.2 CDS xynP NC_000964.3 1887352 1888743 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16684115, 16850406, 17183216; Product type pt: transporter; symporter 1887352..1888743 Bacillus subtilis subsp. subtilis str. 168 939533 NP_389640.2 CDS xynB NC_000964.3 1888774 1890375 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16684115, 2440680, 6413490, 7816035, 9286998, 9973552; Product type e : enzyme; beta-xylosidase 1888774..1890375 Bacillus subtilis subsp. subtilis str. 168 939472 NP_389641.2 CDS xylR NC_000964.3 1890512 1891564 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1588910, 1719948, 2544559, 7559331; Product type r: regulator; transcriptional regulator complement(1890512..1891564) Bacillus subtilis subsp. subtilis str. 168 939531 NP_389642.2 CDS xylA NC_000964.3 1891908 1893245 D catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1891908..1893245 Bacillus subtilis subsp. subtilis str. 168 939558 NP_389643.1 CDS xylB NC_000964.3 1893396 1894895 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1660563, 8866023; Product type e: enzyme; xylulose kinase 1893396..1894895 Bacillus subtilis subsp. subtilis str. 168 939560 NP_389644.1 CDS yncB NC_000964.3 1895378 1896013 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type e: enzyme; endonuclease complement(1895378..1896013) Bacillus subtilis subsp. subtilis str. 168 939569 NP_389645.2 CDS yncC NC_000964.3 1896424 1897839 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transport protein YncC 1896424..1897839 Bacillus subtilis subsp. subtilis str. 168 939540 NP_389646.1 CDS alrB NC_000964.3 1897941 1899125 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10348844, 18399999; Product type e: enzyme; alanine racemase 2 complement(1897941..1899125) Bacillus subtilis subsp. subtilis str. 168 939550 NP_389648.2 CDS yncE NC_000964.3 1899589 1900050 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1899589..1900050 Bacillus subtilis subsp. subtilis str. 168 939573 NP_389649.1 CDS yncF NC_000964.3 1900080 1900514 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15939294, 16908222, 17169987; Product type h: extrachromosomal origin; deoxyuridine 5'-triphosphate nucleotidohydrolase YncF 1900080..1900514 Bacillus subtilis subsp. subtilis str. 168 939541 NP_389650.1 CDS cotU NC_000964.3 1901117 1901377 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816, 18065538; Product type f: factor; hypothetical protein complement(1901117..1901377) Bacillus subtilis subsp. subtilis str. 168 939580 NP_389651.1 CDS thyA NC_000964.3 1902219 1903058 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1902219..1903058 Bacillus subtilis subsp. subtilis str. 168 939555 NP_389652.1 CDS yncM NC_000964.3 1903511 1904263 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1903511..1904263) Bacillus subtilis subsp. subtilis str. 168 939576 YP_003097731.1 CDS ynzK NC_000964.3 1904393 1904749 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein complement(1904393..1904749) Bacillus subtilis subsp. subtilis str. 168 8303021 NP_389653.2 CDS cotC NC_000964.3 1904995 1905195 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10788508, 11741866, 14762008, 18065538, 2821284; Product type s: structure; spore coat protein C complement(1904995..1905195) Bacillus subtilis subsp. subtilis str. 168 939543 NP_389654.1 CDS tatAC NC_000964.3 1905370 1905558 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775; Product type t: transporter; Sec-independent protein translocase protein TatAc complement(1905370..1905558) Bacillus subtilis subsp. subtilis str. 168 939527 NP_389655.1 CDS yndA NC_000964.3 1905809 1906207 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1905809..1906207 Bacillus subtilis subsp. subtilis str. 168 939521 NP_389656.1 CDS yndB NC_000964.3 1906272 1906706 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1906272..1906706) Bacillus subtilis subsp. subtilis str. 168 939524 NP_389657.2 CDS ynzB NC_000964.3 1907013 1907201 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 1907013..1907201 Bacillus subtilis subsp. subtilis str. 168 939516 NP_389658.1 CDS yndD NC_000964.3 1907494 1909056 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; membrane protein 1907494..1909056 Bacillus subtilis subsp. subtilis str. 168 939529 NP_389659.1 CDS yndE NC_000964.3 1909086 1910177 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component; spore germination protein YndE 1909086..1910177 Bacillus subtilis subsp. subtilis str. 168 936538 NP_389660.1 CDS yndF NC_000964.3 1910167 1911381 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type lp : lipoprotein; spore germination protein YndF 1910167..1911381 Bacillus subtilis subsp. subtilis str. 168 939547 NP_389661.1 CDS yndG NC_000964.3 1911528 1912334 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1911528..1912334 Bacillus subtilis subsp. subtilis str. 168 939565 NP_389662.1 CDS yndH NC_000964.3 1912339 1912956 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1912339..1912956 Bacillus subtilis subsp. subtilis str. 168 939537 NP_389663.1 CDS yndJ NC_000964.3 1912953 1914593 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1912953..1914593 Bacillus subtilis subsp. subtilis str. 168 939575 NP_389664.1 CDS yndK NC_000964.3 1914630 1914995 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 1914630..1914995 Bacillus subtilis subsp. subtilis str. 168 936932 NP_389665.1 CDS yndL NC_000964.3 1915221 1915979 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1915221..1915979 Bacillus subtilis subsp. subtilis str. 168 939553 NP_389666.1 CDS yndM NC_000964.3 1916006 1916545 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(1916006..1916545) Bacillus subtilis subsp. subtilis str. 168 938236 NP_389667.1 CDS yndN NC_000964.3 1916663 1917097 D catalyzes resistance to fosfomycin by the addition of a thiol cofactor; metallothiol transferase FosB 1916663..1917097 Bacillus subtilis subsp. subtilis str. 168 938817 NP_389668.1 CDS lexA NC_000964.3 1917639 1918256 R Represses a number of genes involved in the response to DNA damage; lexa repressor complement(1917639..1918256) Bacillus subtilis subsp. subtilis str. 168 939564 NP_389669.1 CDS yneA NC_000964.3 1918406 1918723 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12581363, 16267290, 16549676; Product type cp: cell process; cell division suppressor protein YneA 1918406..1918723 Bacillus subtilis subsp. subtilis str. 168 936112 NP_389670.1 CDS yneB NC_000964.3 1918742 1919395 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12581363, 16267290, 17020588; Product type cp: cell process; resolvase homolog YneB 1918742..1919395 Bacillus subtilis subsp. subtilis str. 168 939557 NP_389671.1 CDS ynzC NC_000964.3 1919459 1919692 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750; hypothetical protein 1919459..1919692 Bacillus subtilis subsp. subtilis str. 168 939578 NP_389672.1 CDS tkt NC_000964.3 1919861 1921864 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 12882400; Product type e: enzyme; transketolase 1919861..1921864 Bacillus subtilis subsp. subtilis str. 168 937377 NP_389673.1 CDS yneE NC_000964.3 1922017 1922463 D Evidence 4: Homologs of previously reported genes of unknown function; sporulation inhibitor of replication protein SirA 1922017..1922463 Bacillus subtilis subsp. subtilis str. 168 936340 NP_389674.1 CDS yneF NC_000964.3 1922549 1922767 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1922549..1922767 Bacillus subtilis subsp. subtilis str. 168 939469 NP_389675.1 CDS ynzD NC_000964.3 1922841 1923014 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme; aspartyl-phosphate phosphatase YnzD complement(1922841..1923014) Bacillus subtilis subsp. subtilis str. 168 938818 NP_389676.1 CDS ccdA NC_000964.3 1923234 1923941 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16771673, 16850406; Product type e: enzyme; cytochrome c-type biogenesis protein CcdA 1923234..1923941 Bacillus subtilis subsp. subtilis str. 168 937140 NP_389677.1 CDS yneI NC_000964.3 1924030 1924392 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554; Product type pr : regulator; plasmid maintenance protein CcdB 1924030..1924392 Bacillus subtilis subsp. subtilis str. 168 939468 NP_389678.1 CDS yneJ NC_000964.3 1924471 1924962 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1924471..1924962 Bacillus subtilis subsp. subtilis str. 168 938604 NP_389679.1 CDS yneK NC_000964.3 1924993 1925421 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1924993..1925421) Bacillus subtilis subsp. subtilis str. 168 938820 NP_389680.1 CDS cotM NC_000964.3 1925655 1926047 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673, 9068633; Product type m: membrane component; spore coat protein M complement(1925655..1926047) Bacillus subtilis subsp. subtilis str. 168 938815 NP_389681.1 CDS sspP NC_000964.3 1926128 1926274 R SASP P; found in forespore compartment; small acid-soluble spore protein P complement(1926128..1926274) Bacillus subtilis subsp. subtilis str. 168 938192 NP_389682.1 CDS sspO NC_000964.3 1926306 1926452 R SASP O; found in forespore compartment; small acid-soluble spore protein O complement(1926306..1926452) Bacillus subtilis subsp. subtilis str. 168 938222 NP_389683.1 CDS citB NC_000964.3 1926680 1929409 D Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1926680..1929409 Bacillus subtilis subsp. subtilis str. 168 938140 NP_389684.1 CDS yneN NC_000964.3 1929481 1929993 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15342593; Product type pe : enzyme; thioredoxin 1929481..1929993 Bacillus subtilis subsp. subtilis str. 168 938193 YP_003097732.1 CDS ynzL NC_000964.3 1930074 1930199 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1930074..1930199 Bacillus subtilis subsp. subtilis str. 168 8302958 YP_054579.2 CDS sspN NC_000964.3 1930264 1930410 D SASP N; found in forespore compartment; small acid-soluble spore protein N 1930264..1930410 Bacillus subtilis subsp. subtilis str. 168 2914184 NP_389685.1 CDS tlp NC_000964.3 1930447 1930698 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type f: factor; small acid-soluble spore protein Tlp 1930447..1930698 Bacillus subtilis subsp. subtilis str. 168 938091 YP_054580.1 CDS yneP NC_000964.3 1930834 1931199 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl-CoA thioesterase 1930834..1931199 Bacillus subtilis subsp. subtilis str. 168 2914242 NP_389687.1 CDS yneQ NC_000964.3 1931215 1931514 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1931215..1931514 Bacillus subtilis subsp. subtilis str. 168 937998 NP_389688.1 CDS yneR NC_000964.3 1931545 1931832 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1931545..1931832) Bacillus subtilis subsp. subtilis str. 168 938132 NP_389689.1 CDS yneS NC_000964.3 1931920 1932501 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase complement(1931920..1932501) Bacillus subtilis subsp. subtilis str. 168 938037 NP_389690.1 CDS yneT NC_000964.3 1932671 1933078 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1932671..1933078 Bacillus subtilis subsp. subtilis str. 168 938220 NP_389691.2 CDS parE NC_000964.3 1933477 1935444 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase 4 subunit B 1933477..1935444 Bacillus subtilis subsp. subtilis str. 168 936151 NP_389692.2 CDS parC NC_000964.3 1935448 1937868 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase 4 subunit A 1935448..1937868 Bacillus subtilis subsp. subtilis str. 168 937107 NP_389693.1 CDS ynfC NC_000964.3 1938066 1938476 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1938066..1938476) Bacillus subtilis subsp. subtilis str. 168 937092 NP_389694.1 CDS alsT NC_000964.3 1938925 1940322 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12823818, 15849754, 16850406, 8969507; Product type t: transporter; amino acid carrier protein AlsT 1938925..1940322 Bacillus subtilis subsp. subtilis str. 168 938191 NP_389695.2 CDS eglS NC_000964.3 1940625 1942124 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15139916, 3024130, 7710279; Product type e: enzyme; endoglucanase 1940625..1942124 Bacillus subtilis subsp. subtilis str. 168 938607 NP_389696.1 CDS ynfE NC_000964.3 1942192 1942455 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1942192..1942455 Bacillus subtilis subsp. subtilis str. 168 936469 NP_389697.1 CDS xynC NC_000964.3 1942714 1943982 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17028274; Product type e: enzyme; glucuronoxylanase XynC complement(1942714..1943982) Bacillus subtilis subsp. subtilis str. 168 937052 NP_389698.1 CDS xynD NC_000964.3 1944113 1945654 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1938968; Product type e : enzyme; arabinoxylan arabinofuranohydrolase complement(1944113..1945654) Bacillus subtilis subsp. subtilis str. 168 936433 NP_389699.1 CDS yngA NC_000964.3 1946249 1946695 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1946249..1946695 Bacillus subtilis subsp. subtilis str. 168 936300 NP_389700.1 CDS yngB NC_000964.3 1946702 1947595 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8320212; Product type pe : enzyme; UTP--glucose-1-phosphate uridylyltransferase YngB 1946702..1947595 Bacillus subtilis subsp. subtilis str. 168 936791 NP_389701.1 CDS yngC NC_000964.3 1947668 1948264 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1947668..1948264 Bacillus subtilis subsp. subtilis str. 168 939567 NP_389702.1 CDS yngD NC_000964.3 1948313 1949512 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oligoribonuclease NrnB complement(1948313..1949512) Bacillus subtilis subsp. subtilis str. 168 936020 NP_389703.2 CDS yngE NC_000964.3 1949682 1951217 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carboxylase YngE complement(1949682..1951217) Bacillus subtilis subsp. subtilis str. 168 939528 NP_389704.1 CDS yngF NC_000964.3 1951228 1952010 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase/isomerase YngF complement(1951228..1952010) Bacillus subtilis subsp. subtilis str. 168 939467 NP_389705.1 CDS yngG NC_000964.3 1952031 1952930 R catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; hydroxymethylglutaryl-CoA lyase YngG complement(1952031..1952930) Bacillus subtilis subsp. subtilis str. 168 939515 YP_003097733.1 CDS yngHB NC_000964.3 1952945 1953166 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin/lipoyl attachment protein complement(1952945..1953166) Bacillus subtilis subsp. subtilis str. 168 8303012 NP_389706.1 CDS yngH NC_000964.3 1953181 1954515 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 2 complement(1953181..1954515) Bacillus subtilis subsp. subtilis str. 168 939474 NP_389707.1 CDS yngI NC_000964.3 1954525 1956174 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12535077, 15213221; Product type e: enzyme; acyl-CoA synthetase YngI complement(1954525..1956174) Bacillus subtilis subsp. subtilis str. 168 939571 NP_389708.1 CDS yngJ NC_000964.3 1956218 1957360 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8655474; Product type e: enzyme; acyl-CoA dehydrogenase YngJ complement(1956218..1957360) Bacillus subtilis subsp. subtilis str. 168 939996 NP_389709.1 CDS ynzE NC_000964.3 1957451 1957756 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(1957451..1957756) Bacillus subtilis subsp. subtilis str. 168 939980 NP_389710.1 CDS yngK NC_000964.3 1958027 1959559 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type ps : structure; hypothetical protein complement(1958027..1959559) Bacillus subtilis subsp. subtilis str. 168 939977 NP_389711.1 CDS yngL NC_000964.3 1959695 1960087 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(1959695..1960087) Bacillus subtilis subsp. subtilis str. 168 939955 NP_389712.1 CDS ppsE NC_000964.3 1960198 1964037 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486459, 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit E complement(1960198..1964037) Bacillus subtilis subsp. subtilis str. 168 939956 NP_389713.2 CDS ppsD NC_000964.3 1964045 1974856 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit D complement(1964045..1974856) Bacillus subtilis subsp. subtilis str. 168 940013 NP_389714.1 CDS ppsC NC_000964.3 1974881 1982548 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit C complement(1974881..1982548) Bacillus subtilis subsp. subtilis str. 168 940102 NP_389715.1 CDS ppsB NC_000964.3 1982565 1990247 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit B complement(1982565..1990247) Bacillus subtilis subsp. subtilis str. 168 939993 NP_389716.2 CDS ppsA NC_000964.3 1990272 1997957 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit A complement(1990272..1997957) Bacillus subtilis subsp. subtilis str. 168 939983 NP_389717.1 CDS dacC NC_000964.3 1998340 1999815 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160090, 14731276, 9733705, 9864321; Product type e: enzyme; D-alanyl-D-alanine carboxypeptidase DacC complement(1998340..1999815) Bacillus subtilis subsp. subtilis str. 168 939990 NP_389718.1 CDS yoxA NC_000964.3 1999849 2000826 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9733705; Product type pe : enzyme; aldose 1-epimerase complement(1999849..2000826) Bacillus subtilis subsp. subtilis str. 168 938046 NP_389719.2 CDS yoeA NC_000964.3 2000960 2002351 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; multidrug resistance protein complement(2000960..2002351) Bacillus subtilis subsp. subtilis str. 168 939596 NP_389720.2 CDS iseA NC_000964.3 2002637 2003182 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483219, 17581128, 18761694; Product type f: factor; hypothetical protein 2002637..2003182 Bacillus subtilis subsp. subtilis str. 168 939964 NP_389721.2 CDS yoeC NC_000964.3 2003401 2003946 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; integrase/recombinase YoeC complement(2003401..2003946) Bacillus subtilis subsp. subtilis str. 168 939595 NP_389722.1 CDS yoeD NC_000964.3 2004262 2004492 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16880568; Product type pe : enzyme; hypothetical protein complement(2004262..2004492) Bacillus subtilis subsp. subtilis str. 168 939991 NP_389723.1 CDS ggt NC_000964.3 2004677 2006440 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8763966; Product type e : enzyme; gamma-glutamyltranspeptidase 2004677..2006440 Bacillus subtilis subsp. subtilis str. 168 940001 NP_389724.1 CDS ftsR NC_000964.3 2006541 2007398 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17526699; Product type r: regulator; LysR family transcriptional regulator complement(2006541..2007398) Bacillus subtilis subsp. subtilis str. 168 940018 NP_389725.1 CDS yogA NC_000964.3 2007526 2008515 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pe : enzyme; zinc-type alcohol dehydrogenase 2007526..2008515 Bacillus subtilis subsp. subtilis str. 168 940019 NP_389726.2 CDS gltD NC_000964.3 2008572 2010053 R glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase [NADPH] small chain complement(2008572..2010053) Bacillus subtilis subsp. subtilis str. 168 940053 NP_389727.2 CDS gltA NC_000964.3 2010070 2014632 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14570271, 39113, 6769440, 6774712, 7559359; Product type e: enzyme; glutamate synthase [NADPH] large chain complement(2010070..2014632) Bacillus subtilis subsp. subtilis str. 168 940024 NP_389728.2 CDS gltC NC_000964.3 2014779 2015681 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15150225, 17134717, 2548995; Product type r: regulator; LysR family transcriptional regulator 2014779..2015681 Bacillus subtilis subsp. subtilis str. 168 940104 NP_389729.1 CDS proJ NC_000964.3 2015733 2016848 R catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; glutamate 5-kinase complement(2015733..2016848) Bacillus subtilis subsp. subtilis str. 168 940098 NP_389730.2 CDS proH NC_000964.3 2016845 2017738 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme; pyrroline-5-carboxylate reductase 1 complement(2016845..2017738) Bacillus subtilis subsp. subtilis str. 168 940035 NP_389731.1 CDS rtp NC_000964.3 2017886 2018254 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11313334, 15657033, 16822523, 17376071, 17521668; Product type f: factor; replication termination protein complement(2017886..2018254) Bacillus subtilis subsp. subtilis str. 168 940068 NP_389732.1 CDS fabG NC_000964.3 2018554 2019270 R Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase complement(2018554..2019270) Bacillus subtilis subsp. subtilis str. 168 940090 NP_389733.1 CDS yoxC NC_000964.3 2019421 2019726 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2019421..2019726 Bacillus subtilis subsp. subtilis str. 168 940083 NP_389734.1 CDS yoxB NC_000964.3 2019797 2020567 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2019797..2020567 Bacillus subtilis subsp. subtilis str. 168 940087 NP_389735.2 CDS yoaA NC_000964.3 2020611 2021144 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; N-acetyltransferase YoaA 2020611..2021144 Bacillus subtilis subsp. subtilis str. 168 940097 NP_389736.1 CDS yoaB NC_000964.3 2021223 2022467 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 15849754, 16513748, 16850406; Product type t: transporter; transporter complement(2021223..2022467) Bacillus subtilis subsp. subtilis str. 168 940099 NP_389737.1 CDS yoaC NC_000964.3 2022561 2024024 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 1660563, 10094622; Product type e: enzyme; sugar kinase YoaC complement(2022561..2024024) Bacillus subtilis subsp. subtilis str. 168 940100 NP_389738.1 CDS yoaD NC_000964.3 2024042 2025076 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 12193636, 10094622; Product type pe: enzyme; 2-hydroxyacid dehydrogenase YoaD complement(2024042..2025076) Bacillus subtilis subsp. subtilis str. 168 940109 NP_389739.2 CDS yoaE NC_000964.3 2025400 2027442 D Evidence 2b: Function of strongly homologous gene; PubMedId: 17114254, 2170332; Product type e : enzyme; oxidoreductase 2025400..2027442 Bacillus subtilis subsp. subtilis str. 168 940113 NP_389740.1 CDS yoaF NC_000964.3 2027509 2027802 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2027509..2027802 Bacillus subtilis subsp. subtilis str. 168 940103 NP_389741.1 CDS yoaG NC_000964.3 2028175 2028579 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2028175..2028579) Bacillus subtilis subsp. subtilis str. 168 940105 YP_054581.1 CDS yozQ NC_000964.3 2029020 2029313 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2029020..2029313 Bacillus subtilis subsp. subtilis str. 168 2914173 NP_389742.2 CDS yoaH NC_000964.3 2029429 2031114 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pf : factor; methyl-accepting chemotaxis protein YoaH complement(2029429..2031114) Bacillus subtilis subsp. subtilis str. 168 940110 NP_389743.2 CDS yoaI NC_000964.3 2031439 2032890 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 4-hydroxyphenylacetate 3-monooxygenase 2031439..2032890 Bacillus subtilis subsp. subtilis str. 168 940107 NP_389744.1 CDS exlX NC_000964.3 2032927 2033625 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 18971341; Product type e: enzyme; expansin-YoaJ complement(2032927..2033625) Bacillus subtilis subsp. subtilis str. 168 940108 NP_389745.1 CDS yoaK NC_000964.3 2033895 2034572 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2033895..2034572) Bacillus subtilis subsp. subtilis str. 168 940007 NP_389746.1 CDS pelB NC_000964.3 2034745 2035782 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1731776, 2018526, 2185758, 7764549; Product type e: enzyme; pectin lyase 2034745..2035782 Bacillus subtilis subsp. subtilis str. 168 940111 NP_389747.1 CDS yoaM NC_000964.3 2036039 2036722 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2036039..2036722 Bacillus subtilis subsp. subtilis str. 168 940112 YP_003097734.1 CDS yozS NC_000964.3 2037063 2037368 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein complement(2037063..2037368) Bacillus subtilis subsp. subtilis str. 168 8302957 NP_389748.1 CDS yoaN NC_000964.3 2037601 2038779 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11546787, 14697267, 15628860; Product type e: enzyme; oxalate decarboxylase OxdD complement(2037601..2038779) Bacillus subtilis subsp. subtilis str. 168 940006 NP_389749.1 CDS yoaO NC_000964.3 2038902 2039390 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2038902..2039390) Bacillus subtilis subsp. subtilis str. 168 940005 NP_389750.1 CDS yoaP NC_000964.3 2039610 2040365 R Evidence 4: Homologs of previously reported genes of unknown function; N-acetyltransferase YoaP complement(2039610..2040365) Bacillus subtilis subsp. subtilis str. 168 939512 NP_389751.1 CDS yoaQ NC_000964.3 2040673 2041029 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2040673..2041029 Bacillus subtilis subsp. subtilis str. 168 940010 YP_003097735.1 CDS yozT NC_000964.3 2040988 2041227 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2040988..2041227) Bacillus subtilis subsp. subtilis str. 168 8303003 NP_389752.2 CDS yozF NC_000964.3 2041330 2041827 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein complement(2041330..2041827) Bacillus subtilis subsp. subtilis str. 168 939598 NP_389753.1 CDS yoaR NC_000964.3 2041928 2042839 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8631706; Product type pf : factor; hypothetical protein complement(2041928..2042839) Bacillus subtilis subsp. subtilis str. 168 939962 NP_389754.1 CDS yoaS NC_000964.3 2043186 2043668 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406; membrane protein 2043186..2043668 Bacillus subtilis subsp. subtilis str. 168 939982 NP_389755.1 CDS yozG NC_000964.3 2043678 2043932 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2043678..2043932 Bacillus subtilis subsp. subtilis str. 168 940003 NP_389756.1 CDS yoaT NC_000964.3 2044038 2044832 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2044038..2044832 Bacillus subtilis subsp. subtilis str. 168 940132 NP_389757.1 CDS yoaU NC_000964.3 2044956 2045828 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator complement(2044956..2045828) Bacillus subtilis subsp. subtilis str. 168 940127 NP_389758.1 CDS cyeA NC_000964.3 2045929 2046807 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter; transporter 2045929..2046807 Bacillus subtilis subsp. subtilis str. 168 940126 NP_389759.1 CDS yoaW NC_000964.3 2046980 2047411 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type ph: phenotype; hypothetical protein complement(2046980..2047411) Bacillus subtilis subsp. subtilis str. 168 940131 NP_389760.1 CDS yoaZ NC_000964.3 2047675 2048307 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16181642; Product type pf : factor; protease YoaZ complement(2047675..2048307) Bacillus subtilis subsp. subtilis str. 168 940031 NP_389761.1 CDS penP NC_000964.3 2048533 2049453 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16944130, 7789815; Product type e: enzyme; beta-lactamase 2048533..2049453 Bacillus subtilis subsp. subtilis str. 168 940129 NP_389762.1 CDS yobA NC_000964.3 2049950 2050312 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2049950..2050312) Bacillus subtilis subsp. subtilis str. 168 940122 NP_389763.1 CDS yobB NC_000964.3 2050689 2050952 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein 2050689..2050952 Bacillus subtilis subsp. subtilis str. 168 940049 NP_389764.1 CDS pps NC_000964.3 2051329 2053929 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphoenolpyruvate synthase complement(2051329..2053929) Bacillus subtilis subsp. subtilis str. 168 939985 NP_389765.1 CDS xynA NC_000964.3 2054599 2055240 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16517552, 8628241; Product type e: enzyme; endo-1,4-beta-xylanase A complement(2054599..2055240) Bacillus subtilis subsp. subtilis str. 168 939861 YP_003097736.1 CDS yozV NC_000964.3 2055868 2056107 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein complement(2055868..2056107) Bacillus subtilis subsp. subtilis str. 168 8303004 NP_389766.1 CDS yobD NC_000964.3 2056278 2056616 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; XRE family transcriptional regulator 2056278..2056616 Bacillus subtilis subsp. subtilis str. 168 939975 NP_389767.2 CDS yozH NC_000964.3 2056650 2057006 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2056650..2057006) Bacillus subtilis subsp. subtilis str. 168 939603 NP_389768.1 CDS yozI NC_000964.3 2057214 2057579 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2057214..2057579 Bacillus subtilis subsp. subtilis str. 168 939961 NP_389769.1 CDS yobE NC_000964.3 2057801 2058460 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2057801..2058460 Bacillus subtilis subsp. subtilis str. 168 939611 NP_389770.1 CDS yobF NC_000964.3 2058715 2059638 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2058715..2059638) Bacillus subtilis subsp. subtilis str. 168 939609 YP_003097737.1 CDS yozW NC_000964.3 2059691 2059864 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2059691..2059864) Bacillus subtilis subsp. subtilis str. 168 8303072 YP_003097738.1 CDS yozX NC_000964.3 2060009 2060233 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; protein YozX 2060009..2060233 Bacillus subtilis subsp. subtilis str. 168 8303068 NP_389771.1 CDS yozJ NC_000964.3 2060237 2060692 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2060237..2060692) Bacillus subtilis subsp. subtilis str. 168 939606 YP_003097739.1 CDS yozY NC_000964.3 2060817 2061077 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2060817..2061077 Bacillus subtilis subsp. subtilis str. 168 8303063 NP_389772.1 CDS rapK NC_000964.3 2062150 2063265 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme; response regulator aspartate phosphatase K 2062150..2063265 Bacillus subtilis subsp. subtilis str. 168 939604 NP_389773.1 CDS phrK NC_000964.3 2063262 2063384 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587781, 16816200; Product type r: regulator; phosphatase RapK inhibitor 2063262..2063384 Bacillus subtilis subsp. subtilis str. 168 939608 NP_389774.2 CDS yobH NC_000964.3 2063510 2064163 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA repair protein complement(2063510..2064163) Bacillus subtilis subsp. subtilis str. 168 939613 NP_389775.1 CDS yozK NC_000964.3 2064200 2064547 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12137951; Product type h : extrachromosomal origin; DNA repair protein UvrX complement(2064200..2064547) Bacillus subtilis subsp. subtilis str. 168 939614 NP_389776.1 CDS yozL NC_000964.3 2064540 2064833 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951; hypothetical protein complement(2064540..2064833) Bacillus subtilis subsp. subtilis str. 168 939619 NP_389777.1 CDS yozM NC_000964.3 2065042 2065377 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; prophage-derived-like protein YozM 2065042..2065377 Bacillus subtilis subsp. subtilis str. 168 939622 NP_389778.1 CDS yobI NC_000964.3 2065424 2069029 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15128444; Product type pe : enzyme; membrane protein complement(2065424..2069029) Bacillus subtilis subsp. subtilis str. 168 939615 NP_389779.1 CDS yobJ NC_000964.3 2070244 2071086 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2070244..2071086) Bacillus subtilis subsp. subtilis str. 168 939633 NP_389780.1 CDS yobK NC_000964.3 2071286 2071744 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(2071286..2071744) Bacillus subtilis subsp. subtilis str. 168 939629 NP_389781.1 CDS yobL NC_000964.3 2071754 2073556 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(2071754..2073556) Bacillus subtilis subsp. subtilis str. 168 939624 NP_389782.2 CDS yobM NC_000964.3 2073658 2074221 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(2073658..2074221) Bacillus subtilis subsp. subtilis str. 168 939634 NP_389783.1 CDS yobN NC_000964.3 2074439 2075779 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amine oxidase 2074439..2075779 Bacillus subtilis subsp. subtilis str. 168 939632 NP_389784.1 CDS yobO NC_000964.3 2076206 2078626 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; phage-related protein YobO 2076206..2078626 Bacillus subtilis subsp. subtilis str. 168 939627 NP_389785.1 CDS csaA NC_000964.3 2079214 2079546 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658654, 10816431, 13129613, 15856219, 17372352; Product type f: factor; protein CsaA complement(2079214..2079546) Bacillus subtilis subsp. subtilis str. 168 939631 NP_389786.1 CDS yobQ NC_000964.3 2079611 2080336 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator complement(2079611..2080336) Bacillus subtilis subsp. subtilis str. 168 939637 NP_389787.1 CDS yobR NC_000964.3 2080351 2081094 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; acetyltransferase complement(2080351..2081094) Bacillus subtilis subsp. subtilis str. 168 939650 NP_389788.1 CDS yobS NC_000964.3 2081172 2081747 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator complement(2081172..2081747) Bacillus subtilis subsp. subtilis str. 168 939639 NP_389789.1 CDS yobT NC_000964.3 2081753 2082454 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2081753..2082454) Bacillus subtilis subsp. subtilis str. 168 939645 NP_389790.1 CDS yobU NC_000964.3 2082531 2083013 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; transcriptional regulator complement(2082531..2083013) Bacillus subtilis subsp. subtilis str. 168 939647 NP_389791.1 CDS yobV NC_000964.3 2083067 2084008 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; DeoR family transcriptional regulator complement(2083067..2084008) Bacillus subtilis subsp. subtilis str. 168 939644 NP_389792.1 CDS yobW NC_000964.3 2084214 2084759 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8990290; Product type f: factor; mother cell-specific membrane sporulation protein 2084214..2084759 Bacillus subtilis subsp. subtilis str. 168 939656 NP_389793.1 CDS czrA NC_000964.3 2084786 2085109 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator; ArsR family transcriptional regulator complement(2084786..2085109) Bacillus subtilis subsp. subtilis str. 168 939658 NP_389794.1 CDS yocA NC_000964.3 2085303 2085980 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 2085303..2085980 Bacillus subtilis subsp. subtilis str. 168 939661 NP_389795.1 CDS yozB NC_000964.3 2086070 2086606 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(2086070..2086606) Bacillus subtilis subsp. subtilis str. 168 939655 NP_389796.1 CDS yocB NC_000964.3 2086743 2087525 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2086743..2087525) Bacillus subtilis subsp. subtilis str. 168 939442 NP_389797.1 CDS yocC NC_000964.3 2087696 2088193 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2087696..2088193 Bacillus subtilis subsp. subtilis str. 168 939666 NP_389798.1 CDS yocD NC_000964.3 2088257 2089234 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carboxypeptidase YocD 2088257..2089234 Bacillus subtilis subsp. subtilis str. 168 939659 NP_389799.1 CDS des NC_000964.3 2089396 2090454 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12207704, 15247225, 15711796, 16105701; Product type e: enzyme; fatty acid desaturase 2089396..2090454 Bacillus subtilis subsp. subtilis str. 168 939668 NP_389800.1 CDS desK NC_000964.3 2090574 2091686 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type rc : receptor; sensor histidine kinase 2090574..2091686 Bacillus subtilis subsp. subtilis str. 168 939678 NP_389801.1 CDS desR NC_000964.3 2091705 2092304 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type r : regulator; transcriptional regulatory protein DesR 2091705..2092304 Bacillus subtilis subsp. subtilis str. 168 939664 NP_389802.1 CDS yocH NC_000964.3 2092899 2093762 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17307850; Product type pf : factor; cell wall-binding protein YocH complement(2092899..2093762) Bacillus subtilis subsp. subtilis str. 168 939673 NP_389803.1 CDS yocI NC_000964.3 2094010 2095785 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886746; Product type pe : enzyme; ATP-dependent DNA helicase RecQ complement(2094010..2095785) Bacillus subtilis subsp. subtilis str. 168 939671 NP_389804.1 CDS yocJ NC_000964.3 2096350 2096976 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; FMN-dependent NADH-azoreductase 1 complement(2096350..2096976) Bacillus subtilis subsp. subtilis str. 168 939669 NP_389805.2 CDS yocK NC_000964.3 2097126 2097617 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor; general stress protein 16O complement(2097126..2097617) Bacillus subtilis subsp. subtilis str. 168 939676 NP_389806.1 CDS yocL NC_000964.3 2097692 2098024 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2097692..2098024) Bacillus subtilis subsp. subtilis str. 168 939586 YP_003097740.1 CDS yoyB NC_000964.3 2098102 2098329 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2098102..2098329 Bacillus subtilis subsp. subtilis str. 168 8303149 NP_389808.1 CDS yocM NC_000964.3 2098316 2098792 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11150673; Product type ps : structure; hypothetical protein complement(2098316..2098792) Bacillus subtilis subsp. subtilis str. 168 939587 NP_389809.1 CDS yozN NC_000964.3 2098859 2099122 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2098859..2099122 Bacillus subtilis subsp. subtilis str. 168 939679 NP_389810.1 CDS yocN NC_000964.3 2099127 2099360 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2099127..2099360 Bacillus subtilis subsp. subtilis str. 168 939594 NP_389811.1 CDS yozO NC_000964.3 2099446 2099790 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2099446..2099790) Bacillus subtilis subsp. subtilis str. 168 939681 NP_389812.1 CDS yozC NC_000964.3 2100147 2100350 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2100147..2100350) Bacillus subtilis subsp. subtilis str. 168 939998 NP_389813.1 CDS dhaS NC_000964.3 2100580 2102067 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase DhaS 2100580..2102067 Bacillus subtilis subsp. subtilis str. 168 939963 NP_389814.2 CDS sqhC NC_000964.3 2102168 2104066 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2253626; Product type e: enzyme; sporulenol synthase 2102168..2104066 Bacillus subtilis subsp. subtilis str. 168 939443 NP_389815.1 CDS sodF NC_000964.3 2104056 2104901 D Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; superoxide dismutase 2104056..2104901 Bacillus subtilis subsp. subtilis str. 168 939503 NP_389816.1 CDS yocR NC_000964.3 2104934 2106271 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YocR complement(2104934..2106271) Bacillus subtilis subsp. subtilis str. 168 939450 NP_389817.1 CDS yocS NC_000964.3 2106490 2107455 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YocS 2106490..2107455 Bacillus subtilis subsp. subtilis str. 168 939452 NP_389818.2 CDS odhB NC_000964.3 2107505 2108758 R component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex complement(2107505..2108758) Bacillus subtilis subsp. subtilis str. 168 939505 NP_389819.3 CDS sucA NC_000964.3 2108774 2111608 R SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component complement(2108774..2111608) Bacillus subtilis subsp. subtilis str. 168 939507 NP_389820.2 CDS yojO NC_000964.3 2111837 2113753 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein complement(2111837..2113753) Bacillus subtilis subsp. subtilis str. 168 939499 NP_389821.1 CDS yojN NC_000964.3 2113764 2114678 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15491156; Product type pe : enzyme; hypothetical protein complement(2113764..2114678) Bacillus subtilis subsp. subtilis str. 168 939458 NP_389822.1 CDS sodC NC_000964.3 2114742 2115332 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15897454; Product type lp: lipoprotein; superoxide dismutase-like protein YojM complement(2114742..2115332) Bacillus subtilis subsp. subtilis str. 168 939502 NP_389823.1 CDS cwlS NC_000964.3 2115425 2116669 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244; Product type e: enzyme; D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS complement(2115425..2116669) Bacillus subtilis subsp. subtilis str. 168 939459 NP_389824.2 CDS yojK NC_000964.3 2117051 2118268 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YojK complement(2117051..2118268) Bacillus subtilis subsp. subtilis str. 168 939457 NP_389825.3 CDS yojJ NC_000964.3 2118504 2119127 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2118504..2119127) Bacillus subtilis subsp. subtilis str. 168 939589 NP_389826.1 CDS yojI NC_000964.3 2119393 2120751 D NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug resistance protein NorM 2119393..2120751 Bacillus subtilis subsp. subtilis str. 168 939592 NP_389827.1 CDS rsbRC NC_000964.3 2120767 2121615 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor; RsbT co-antagonist protein RsbRC 2120767..2121615 Bacillus subtilis subsp. subtilis str. 168 940093 YP_054582.2 CDS yojG NC_000964.3 2121641 2122306 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15136574; Product type pe : enzyme; deacetylase YojG complement(2121641..2122306) Bacillus subtilis subsp. subtilis str. 168 2914250 NP_389829.1 CDS yojF NC_000964.3 2122325 2122675 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2122325..2122675) Bacillus subtilis subsp. subtilis str. 168 939590 YP_003097741.1 CDS yoyC NC_000964.3 2122672 2122950 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2122672..2122950) Bacillus subtilis subsp. subtilis str. 168 8303009 NP_389830.2 CDS yojE NC_000964.3 2123026 2123922 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; transporter complement(2123026..2123922) Bacillus subtilis subsp. subtilis str. 168 939447 YP_054583.1 CDS gerT NC_000964.3 2124021 2124494 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17720779; Product type s: structure; spore germination protein GerT 2124021..2124494 Bacillus subtilis subsp. subtilis str. 168 2914248 NP_389832.1 CDS yojB NC_000964.3 2124529 2124765 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2124529..2124765) Bacillus subtilis subsp. subtilis str. 168 939446 NP_389833.1 CDS yojA NC_000964.3 2124850 2126184 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 3020045; Product type pt: transporter; permease YojA complement(2124850..2126184) Bacillus subtilis subsp. subtilis str. 168 939510 NP_389834.1 CDS yodA NC_000964.3 2126549 2126938 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YolI 2126549..2126938 Bacillus subtilis subsp. subtilis str. 168 939461 NP_389835.1 CDS yodB NC_000964.3 2127345 2127683 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17158660, 18208493; Product type r: regulator; ArsR family transcriptional regulator complement(2127345..2127683) Bacillus subtilis subsp. subtilis str. 168 939449 NP_389836.1 CDS yodC NC_000964.3 2127813 2128421 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H nitroreductase 2127813..2128421 Bacillus subtilis subsp. subtilis str. 168 939506 NP_389837.1 CDS yodD NC_000964.3 2128464 2129066 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; hydrolase MhqD complement(2128464..2129066) Bacillus subtilis subsp. subtilis str. 168 940106 NP_389838.1 CDS yodE NC_000964.3 2129082 2129993 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqE complement(2129082..2129993) Bacillus subtilis subsp. subtilis str. 168 940022 YP_003097742.1 CDS yoyD NC_000964.3 2130177 2130377 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; membrane protein 2130177..2130377 Bacillus subtilis subsp. subtilis str. 168 8303187 NP_389839.1 CDS yodF NC_000964.3 2130377 2131867 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823818, 15849754, 16850406; Product type pt: transporter; symporter 2130377..2131867 Bacillus subtilis subsp. subtilis str. 168 940028 NP_389840.1 CDS ctpA NC_000964.3 2131902 2133302 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10974125, 14526016, 8996100; Product type e : enzyme; carboxy-terminal processing protease CtpA complement(2131902..2133302) Bacillus subtilis subsp. subtilis str. 168 940115 NP_389841.1 CDS yodH NC_000964.3 2133455 2134156 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 2133455..2134156 Bacillus subtilis subsp. subtilis str. 168 940101 NP_389842.1 CDS yodI NC_000964.3 2134244 2134495 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2134244..2134495 Bacillus subtilis subsp. subtilis str. 168 940039 NP_389843.1 CDS yodJ NC_000964.3 2134566 2135387 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187182, 8631706; Product type e: enzyme; carboxypeptidase YodJ complement(2134566..2135387) Bacillus subtilis subsp. subtilis str. 168 940023 NP_389844.1 CDS deoD NC_000964.3 2135470 2136171 R catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase DeoD-type complement(2135470..2136171) Bacillus subtilis subsp. subtilis str. 168 940038 YP_003097743.1 CDS yoyE NC_000964.3 2136373 2136498 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2136373..2136498 Bacillus subtilis subsp. subtilis str. 168 8303105 NP_389845.2 CDS yodL NC_000964.3 2136538 2136852 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2136538..2136852) Bacillus subtilis subsp. subtilis str. 168 940030 NP_389846.1 CDS yodM NC_000964.3 2136913 2137524 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; lipid phosphate phosphatase YodM complement(2136913..2137524) Bacillus subtilis subsp. subtilis str. 168 940034 NP_389847.1 CDS yozD NC_000964.3 2137602 2137778 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2137602..2137778) Bacillus subtilis subsp. subtilis str. 168 940042 YP_003097744.1 CDS yoyF NC_000964.3 2137897 2138040 D Evidence 5: No homology to any previously reported sequences; membrane protein 2137897..2138040 Bacillus subtilis subsp. subtilis str. 168 8303015 NP_389848.1 CDS yodN NC_000964.3 2138037 2138717 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2138037..2138717) Bacillus subtilis subsp. subtilis str. 168 940037 NP_389849.1 CDS yozE NC_000964.3 2138868 2139092 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2138868..2139092) Bacillus subtilis subsp. subtilis str. 168 940055 YP_003097745.1 CDS yokU NC_000964.3 2139179 2139457 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2139179..2139457) Bacillus subtilis subsp. subtilis str. 168 8303010 NP_389850.1 CDS kamA NC_000964.3 2139454 2140869 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629195, 10839984, 11148055, 18307109; Product type e: enzyme; L-lysine 2,3-aminomutase complement(2139454..2140869) Bacillus subtilis subsp. subtilis str. 168 940040 NP_389851.1 CDS yodP NC_000964.3 2140898 2141725 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YodP complement(2140898..2141725) Bacillus subtilis subsp. subtilis str. 168 940057 NP_389852.1 CDS yodQ NC_000964.3 2141703 2143013 R catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; metallohydrolase YodQ complement(2141703..2143013) Bacillus subtilis subsp. subtilis str. 168 940044 NP_389853.1 CDS yodR NC_000964.3 2143022 2143675 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; coenzyme A transferase subunit beta complement(2143022..2143675) Bacillus subtilis subsp. subtilis str. 168 940048 NP_389854.1 CDS yodS NC_000964.3 2143660 2144349 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; coenzyme A transferase subunit alpha complement(2143660..2144349) Bacillus subtilis subsp. subtilis str. 168 940052 NP_389855.1 CDS yodT NC_000964.3 2144356 2145690 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminotransferase YodT complement(2144356..2145690) Bacillus subtilis subsp. subtilis str. 168 940050 YP_003097746.1 CDS yoyG NC_000964.3 2145820 2145933 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2145820..2145933) Bacillus subtilis subsp. subtilis str. 168 8302971 NP_389856.1 CDS cgeE NC_000964.3 2146013 2146792 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; N-acetyltransferase CgeE complement(2146013..2146792) Bacillus subtilis subsp. subtilis str. 168 940064 NP_389857.1 CDS cgeD NC_000964.3 2146821 2148101 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeD complement(2146821..2148101) Bacillus subtilis subsp. subtilis str. 168 940063 NP_389858.1 CDS cgeC NC_000964.3 2148166 2148471 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeC complement(2148166..2148471) Bacillus subtilis subsp. subtilis str. 168 940074 NP_389859.1 CDS cgeA NC_000964.3 2148676 2149077 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702409, 15621419, 759239; Product type cp: cell process; spore maturation protein CgeA 2148676..2149077 Bacillus subtilis subsp. subtilis str. 168 940066 NP_389860.2 CDS cgeB NC_000964.3 2149084 2150037 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeB 2149084..2150037 Bacillus subtilis subsp. subtilis str. 168 940061 NP_389861.1 CDS phy NC_000964.3 2150108 2151256 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10679209, 12111145, 12556126; Product type e: enzyme; 3-phytase complement(2150108..2151256) Bacillus subtilis subsp. subtilis str. 168 940065 NP_389863.1 CDS yotN NC_000964.3 2152086 2152262 R Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein complement(2152086..2152262) Bacillus subtilis subsp. subtilis str. 168 940072 NP_389864.1 CDS yotM NC_000964.3 2152265 2152852 R Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein complement(2152265..2152852) Bacillus subtilis subsp. subtilis str. 168 940081 NP_389865.1 CDS yotL NC_000964.3 2152927 2153169 D Evidence 4: Homologs of previously reported genes of unknown function; XRE family transcriptional regulator 2152927..2153169 Bacillus subtilis subsp. subtilis str. 168 940077 NP_389866.1 CDS yotK NC_000964.3 2153171 2153356 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2153171..2153356) Bacillus subtilis subsp. subtilis str. 168 939549 NP_389867.1 CDS yotJ NC_000964.3 2153440 2153652 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2153440..2153652) Bacillus subtilis subsp. subtilis str. 168 940079 NP_389868.1 CDS yotI NC_000964.3 2153718 2154080 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2153718..2154080) Bacillus subtilis subsp. subtilis str. 168 940078 NP_389869.1 CDS yotH NC_000964.3 2154077 2154250 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(2154077..2154250) Bacillus subtilis subsp. subtilis str. 168 940084 NP_389870.1 CDS yotG NC_000964.3 2154266 2154583 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2154266..2154583) Bacillus subtilis subsp. subtilis str. 168 940082 NP_389871.1 CDS yotF NC_000964.3 2154596 2154673 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2154596..2154673) Bacillus subtilis subsp. subtilis str. 168 940086 NP_389872.1 CDS yotE NC_000964.3 2154705 2154851 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2154705..2154851) Bacillus subtilis subsp. subtilis str. 168 939566 NP_389873.1 CDS yotD NC_000964.3 2154887 2155018 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2154887..2155018) Bacillus subtilis subsp. subtilis str. 168 940092 NP_389874.1 CDS yotC NC_000964.3 2155058 2155249 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2155058..2155249) Bacillus subtilis subsp. subtilis str. 168 940094 NP_389875.1 CDS yotB NC_000964.3 2155293 2156120 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2155293..2156120) Bacillus subtilis subsp. subtilis str. 168 940114 NP_389876.1 CDS sspC NC_000964.3 2156239 2156457 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 12234173, 14526021, 15150240; Product type s: structure; small acid-soluble spore protein C 2156239..2156457 Bacillus subtilis subsp. subtilis str. 168 939473 NP_389878.1 CDS yosX NC_000964.3 2156757 2157110 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2156757..2157110) Bacillus subtilis subsp. subtilis str. 168 939517 NP_389879.1 CDS yosW NC_000964.3 2157341 2157682 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(2157341..2157682) Bacillus subtilis subsp. subtilis str. 168 938813 NP_389880.1 CDS yosV NC_000964.3 2157829 2158119 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2157829..2158119) Bacillus subtilis subsp. subtilis str. 168 939523 YP_003097747.1 CDS yojW NC_000964.3 2158120 2158287 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2158120..2158287) Bacillus subtilis subsp. subtilis str. 168 8302977 NP_389881.1 CDS yosU NC_000964.3 2158439 2158684 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2158439..2158684 Bacillus subtilis subsp. subtilis str. 168 939552 NP_389882.1 CDS yosT NC_000964.3 2158724 2159173 R Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator YosT complement(2158724..2159173) Bacillus subtilis subsp. subtilis str. 168 939471 NP_389883.1 CDS yosS NC_000964.3 2159268 2159696 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11375514, 15939294; Product type h: extrachromosomal origin; deoxyuridine 5'-triphosphate nucleotidohydrolase YosS complement(2159268..2159696) Bacillus subtilis subsp. subtilis str. 168 939536 NP_389884.1 CDS yosR NC_000964.3 2159742 2159984 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16885274, 17395719; Product type h: extrachromosomal origin; thioredoxin complement(2159742..2159984) Bacillus subtilis subsp. subtilis str. 168 939513 NP_389886.2 CDS nrdF NC_000964.3 2159981 2161778 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleoside-diphosphate reductase subunit beta complement(join(2159981..2160388,2161197..2161778)) Bacillus subtilis subsp. subtilis str. 168 939476 NP_389885.1 CDS yosQ NC_000964.3 2160565 2161086 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type h: extrachromosomal origin; HNH homing endonuclease YosQ complement(2160565..2161086) Bacillus subtilis subsp. subtilis str. 168 939514 NP_389888.2 CDS nrdEB NC_000964.3 2162108 2165614 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type e: enzyme; ribonucleoside-diphosphate reductase NrdEB subunit alpha complement(join(2162108..2164642,2164895..2165614)) Bacillus subtilis subsp. subtilis str. 168 939475 NP_389889.1 CDS nrdI NC_000964.3 2165577 2165966 R in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein NrdI complement(2165577..2165966) Bacillus subtilis subsp. subtilis str. 168 939562 NP_389890.1 CDS yosL NC_000964.3 2165972 2166325 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2165972..2166325) Bacillus subtilis subsp. subtilis str. 168 939559 NP_389891.1 CDS yosK NC_000964.3 2166413 2166613 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2166413..2166613) Bacillus subtilis subsp. subtilis str. 168 939546 NP_389892.1 CDS yosJ NC_000964.3 2166658 2166852 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2166658..2166852) Bacillus subtilis subsp. subtilis str. 168 939556 NP_389893.1 CDS yosI NC_000964.3 2166873 2167007 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2166873..2167007) Bacillus subtilis subsp. subtilis str. 168 939563 NP_389894.1 CDS yosH NC_000964.3 2167039 2167509 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2167039..2167509) Bacillus subtilis subsp. subtilis str. 168 939551 NP_389895.1 CDS yosG NC_000964.3 2167570 2167932 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2167570..2167932) Bacillus subtilis subsp. subtilis str. 168 939570 NP_389896.1 CDS yosF NC_000964.3 2167975 2168100 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2167975..2168100) Bacillus subtilis subsp. subtilis str. 168 939526 NP_389897.1 CDS yosE NC_000964.3 2168114 2168461 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(2168114..2168461) Bacillus subtilis subsp. subtilis str. 168 939572 NP_389898.1 CDS yosD NC_000964.3 2168476 2168871 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2168476..2168871) Bacillus subtilis subsp. subtilis str. 168 939554 NP_389899.1 CDS yosC NC_000964.3 2168910 2169452 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2168910..2169452) Bacillus subtilis subsp. subtilis str. 168 939561 NP_389900.1 CDS yosB NC_000964.3 2169497 2169676 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2169497..2169676) Bacillus subtilis subsp. subtilis str. 168 939568 NP_389901.1 CDS yosA NC_000964.3 2169807 2169926 D Evidence 5: No homology to any previously reported sequences; Product type h: extrachromosomal origin; hypothetical protein 2169807..2169926 Bacillus subtilis subsp. subtilis str. 168 939574 NP_389902.1 CDS yorZ NC_000964.3 2170030 2170242 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2170030..2170242) Bacillus subtilis subsp. subtilis str. 168 939577 NP_389903.1 CDS yorY NC_000964.3 2170309 2170491 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2170309..2170491) Bacillus subtilis subsp. subtilis str. 168 939519 NP_389904.1 CDS yorX NC_000964.3 2170504 2170731 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2170504..2170731) Bacillus subtilis subsp. subtilis str. 168 939737 NP_389905.1 CDS yorW NC_000964.3 2170771 2171136 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2170771..2171136) Bacillus subtilis subsp. subtilis str. 168 939522 NP_389906.1 CDS yorV NC_000964.3 2171139 2171357 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(2171139..2171357) Bacillus subtilis subsp. subtilis str. 168 939579 NP_389907.1 CDS mtbP NC_000964.3 2171401 2172732 R Evidence 2b: Function of strongly homologous gene; Product type h: extrachromosomal origin; Phi-3T prophage-derived modification methylase Phi3TI complement(2171401..2172732) Bacillus subtilis subsp. subtilis str. 168 939532 NP_389908.1 CDS yorT NC_000964.3 2172781 2172900 R Evidence 6: Doubtful CDS; hypothetical protein complement(2172781..2172900) Bacillus subtilis subsp. subtilis str. 168 939525 NP_389909.1 CDS yorS NC_000964.3 2172932 2173450 R Evidence 4: Homologs of previously reported genes of unknown function; 5'(3')-deoxyribonucleotidase complement(2172932..2173450) Bacillus subtilis subsp. subtilis str. 168 939520 NP_389910.1 CDS yorR NC_000964.3 2173459 2173956 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2173459..2173956) Bacillus subtilis subsp. subtilis str. 168 939530 NP_389911.1 CDS yorQ NC_000964.3 2173956 2174111 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2173956..2174111) Bacillus subtilis subsp. subtilis str. 168 939534 NP_389912.1 CDS yorP NC_000964.3 2174104 2174319 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2174104..2174319) Bacillus subtilis subsp. subtilis str. 168 939535 NP_389913.1 CDS yorO NC_000964.3 2174352 2174549 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2174352..2174549) Bacillus subtilis subsp. subtilis str. 168 939542 NP_389914.1 CDS yorN NC_000964.3 2174585 2174734 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2174585..2174734) Bacillus subtilis subsp. subtilis str. 168 939538 NP_389915.1 CDS yorM NC_000964.3 2174852 2175568 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2174852..2175568) Bacillus subtilis subsp. subtilis str. 168 939539 NP_389916.1 CDS yorL NC_000964.3 2175596 2179513 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA polymerase YorL complement(2175596..2179513) Bacillus subtilis subsp. subtilis str. 168 939437 NP_389917.1 CDS yorK NC_000964.3 2179526 2181256 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; single-strand DNA-specific exonuclease YorK complement(2179526..2181256) Bacillus subtilis subsp. subtilis str. 168 939545 NP_389918.1 CDS yorJ NC_000964.3 2181256 2182392 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2181256..2182392) Bacillus subtilis subsp. subtilis str. 168 939584 NP_389919.1 CDS yorI NC_000964.3 2182408 2183922 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2182408..2183922) Bacillus subtilis subsp. subtilis str. 168 939707 NP_389920.1 CDS yorH NC_000964.3 2183937 2184407 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2183937..2184407) Bacillus subtilis subsp. subtilis str. 168 939851 NP_389921.1 CDS yorG NC_000964.3 2184450 2185421 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2184450..2185421) Bacillus subtilis subsp. subtilis str. 168 939865 NP_389922.1 CDS yorF NC_000964.3 2185504 2186418 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2185504..2186418) Bacillus subtilis subsp. subtilis str. 168 940146 NP_389923.1 CDS yorE NC_000964.3 2186440 2186811 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2186440..2186811) Bacillus subtilis subsp. subtilis str. 168 940144 NP_389924.1 CDS yorD NC_000964.3 2186985 2187299 R Evidence 5: No homology to any previously reported sequences; stress response protein SCP1 complement(2186985..2187299) Bacillus subtilis subsp. subtilis str. 168 940145 NP_389925.1 CDS yorC NC_000964.3 2187376 2187756 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2187376..2187756) Bacillus subtilis subsp. subtilis str. 168 936462 NP_389926.1 CDS yorB NC_000964.3 2187819 2188115 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2187819..2188115) Bacillus subtilis subsp. subtilis str. 168 939951 NP_389927.1 CDS yorA NC_000964.3 2188204 2189964 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2188204..2189964) Bacillus subtilis subsp. subtilis str. 168 940009 NP_389928.1 CDS yoqZ NC_000964.3 2189961 2190785 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2189961..2190785) Bacillus subtilis subsp. subtilis str. 168 939582 NP_389929.1 CDS yoqY NC_000964.3 2190884 2191279 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2190884..2191279) Bacillus subtilis subsp. subtilis str. 168 939509 NP_389930.1 CDS yoqX NC_000964.3 2191334 2191555 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(2191334..2191555) Bacillus subtilis subsp. subtilis str. 168 939597 NP_389931.1 CDS yoqW NC_000964.3 2191626 2192300 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2191626..2192300 Bacillus subtilis subsp. subtilis str. 168 939979 NP_389932.1 CDS ligB NC_000964.3 2192370 2193182 D catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase-like protein LigB 2192370..2193182 Bacillus subtilis subsp. subtilis str. 168 939992 NP_389933.1 CDS yoqU NC_000964.3 2193248 2193661 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2193248..2193661) Bacillus subtilis subsp. subtilis str. 168 940143 NP_389934.1 CDS yoqT NC_000964.3 2193827 2193976 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2193827..2193976 Bacillus subtilis subsp. subtilis str. 168 939616 NP_389935.1 CDS yoqS NC_000964.3 2194053 2194400 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2194053..2194400) Bacillus subtilis subsp. subtilis str. 168 939995 NP_389936.1 CDS yoqR NC_000964.3 2194402 2194758 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2194402..2194758) Bacillus subtilis subsp. subtilis str. 168 939440 NP_389937.1 CDS yoqP NC_000964.3 2194718 2195059 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2194718..2195059) Bacillus subtilis subsp. subtilis str. 168 939583 NP_389938.1 CDS yoqO NC_000964.3 2195173 2195547 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2195173..2195547 Bacillus subtilis subsp. subtilis str. 168 936492 NP_389939.1 CDS yoqN NC_000964.3 2195564 2195782 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2195564..2195782) Bacillus subtilis subsp. subtilis str. 168 936507 NP_389940.1 CDS yoqM NC_000964.3 2195986 2196264 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 2195986..2196264 Bacillus subtilis subsp. subtilis str. 168 939973 NP_389941.1 CDS yoqL NC_000964.3 2196389 2197081 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; HNH endonuclease YoqL complement(2196389..2197081) Bacillus subtilis subsp. subtilis str. 168 939974 NP_389942.1 CDS yoqK NC_000964.3 2197121 2197324 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2197121..2197324) Bacillus subtilis subsp. subtilis str. 168 940015 NP_389943.1 CDS yoqJ NC_000964.3 2197344 2197859 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2197344..2197859) Bacillus subtilis subsp. subtilis str. 168 939585 NP_389944.1 CDS yoqI NC_000964.3 2198070 2198264 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2198070..2198264) Bacillus subtilis subsp. subtilis str. 168 939965 NP_389945.1 CDS yoqH NC_000964.3 2198313 2198765 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2198313..2198765) Bacillus subtilis subsp. subtilis str. 168 939438 NP_389946.1 CDS yoqG NC_000964.3 2198848 2199105 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2198848..2199105) Bacillus subtilis subsp. subtilis str. 168 936494 NP_389947.1 CDS yoqF NC_000964.3 2199150 2199353 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2199150..2199353) Bacillus subtilis subsp. subtilis str. 168 936493 NP_389948.1 CDS yoqE NC_000964.3 2199362 2199526 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2199362..2199526) Bacillus subtilis subsp. subtilis str. 168 939433 NP_389949.1 CDS yoqD NC_000964.3 2199580 2200335 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2661831; Product type pr : regulator; antirepressor protein YoqD complement(2199580..2200335) Bacillus subtilis subsp. subtilis str. 168 939436 NP_389950.1 CDS yoqC NC_000964.3 2200376 2200783 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(2200376..2200783) Bacillus subtilis subsp. subtilis str. 168 936489 NP_389951.1 CDS yoqB NC_000964.3 2200790 2201128 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2200790..2201128) Bacillus subtilis subsp. subtilis str. 168 939431 NP_389952.1 CDS yoqA NC_000964.3 2201125 2201475 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2201125..2201475) Bacillus subtilis subsp. subtilis str. 168 939434 NP_389953.1 CDS yopZ NC_000964.3 2201488 2201691 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2201488..2201691) Bacillus subtilis subsp. subtilis str. 168 936487 NP_389954.1 CDS yopY NC_000964.3 2201705 2201983 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2201705..2201983) Bacillus subtilis subsp. subtilis str. 168 936488 NP_389955.1 CDS yopX NC_000964.3 2201980 2202384 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2201980..2202384) Bacillus subtilis subsp. subtilis str. 168 939430 NP_389956.1 CDS yopW NC_000964.3 2202381 2202716 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2202381..2202716) Bacillus subtilis subsp. subtilis str. 168 936484 NP_389957.1 CDS yopV NC_000964.3 2202805 2202999 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2202805..2202999) Bacillus subtilis subsp. subtilis str. 168 939432 NP_389958.1 CDS yopU NC_000964.3 2203111 2203308 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2203111..2203308) Bacillus subtilis subsp. subtilis str. 168 936485 NP_389959.1 CDS yopT NC_000964.3 2203378 2203596 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2203378..2203596) Bacillus subtilis subsp. subtilis str. 168 939424 NP_389960.1 CDS yopS NC_000964.3 2203779 2204003 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2203779..2204003 Bacillus subtilis subsp. subtilis str. 168 939428 NP_389961.2 CDS yopR NC_000964.3 2204192 2205169 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2204192..2205169) Bacillus subtilis subsp. subtilis str. 168 936483 NP_389962.1 CDS yopQ NC_000964.3 2205193 2206575 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2205193..2206575) Bacillus subtilis subsp. subtilis str. 168 936481 NP_389963.1 CDS yopP NC_000964.3 2206682 2207758 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11208805; Product type pe : enzyme; integrase/recombinase YopP complement(2206682..2207758) Bacillus subtilis subsp. subtilis str. 168 936482 NP_389964.1 CDS yopO NC_000964.3 2207748 2207960 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator complement(2207748..2207960) Bacillus subtilis subsp. subtilis str. 168 939435 NP_389965.1 CDS yopN NC_000964.3 2208008 2208325 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2208008..2208325) Bacillus subtilis subsp. subtilis str. 168 935916 NP_389966.1 CDS yopM NC_000964.3 2208328 2208528 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2208328..2208528) Bacillus subtilis subsp. subtilis str. 168 939186 NP_389967.1 CDS yopL NC_000964.3 2208855 2208980 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2208855..2208980) Bacillus subtilis subsp. subtilis str. 168 939422 NP_389968.1 CDS yopK NC_000964.3 2208994 2210154 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2208994..2210154) Bacillus subtilis subsp. subtilis str. 168 939187 NP_389969.1 CDS yopJ NC_000964.3 2210331 2210747 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(2210331..2210747) Bacillus subtilis subsp. subtilis str. 168 939184 NP_389970.1 CDS yopI NC_000964.3 2210749 2211282 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2210749..2211282) Bacillus subtilis subsp. subtilis str. 168 939182 NP_389971.1 CDS yopH NC_000964.3 2211309 2211845 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2211309..2211845) Bacillus subtilis subsp. subtilis str. 168 939185 NP_389972.1 CDS yopG NC_000964.3 2211884 2212015 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2211884..2212015) Bacillus subtilis subsp. subtilis str. 168 939181 NP_389973.1 CDS yopF NC_000964.3 2212026 2212241 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2212026..2212241) Bacillus subtilis subsp. subtilis str. 168 939179 NP_389974.1 CDS yopE NC_000964.3 2212245 2212496 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2212245..2212496) Bacillus subtilis subsp. subtilis str. 168 939183 YP_003097748.1 CDS yoyH NC_000964.3 2212567 2212746 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2212567..2212746 Bacillus subtilis subsp. subtilis str. 168 8303201 YP_003097749.1 CDS yoyI NC_000964.3 2212848 2213078 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2212848..2213078 Bacillus subtilis subsp. subtilis str. 168 8302920 NP_389976.1 CDS yopD NC_000964.3 2213083 2213478 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2213083..2213478) Bacillus subtilis subsp. subtilis str. 168 939180 NP_389977.1 CDS yopC NC_000964.3 2213536 2214864 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2213536..2214864) Bacillus subtilis subsp. subtilis str. 168 939177 NP_389978.1 CDS yopB NC_000964.3 2214972 2215199 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein complement(2214972..2215199) Bacillus subtilis subsp. subtilis str. 168 939178 NP_389979.1 CDS yopA NC_000964.3 2215460 2216776 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2215460..2216776) Bacillus subtilis subsp. subtilis str. 168 939175 NP_389980.1 CDS yonX NC_000964.3 2217133 2217639 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2217133..2217639) Bacillus subtilis subsp. subtilis str. 168 939173 NP_389981.1 CDS yonV NC_000964.3 2217967 2219199 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2217967..2219199) Bacillus subtilis subsp. subtilis str. 168 939174 NP_389982.1 CDS yonU NC_000964.3 2219281 2219469 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2219281..2219469) Bacillus subtilis subsp. subtilis str. 168 939176 YP_003097750.1 CDS yoyJ NC_000964.3 2219514 2219765 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(2219514..2219765) Bacillus subtilis subsp. subtilis str. 168 8303210 NP_389983.1 CDS yonT NC_000964.3 2219784 2219960 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2219784..2219960) Bacillus subtilis subsp. subtilis str. 168 939172 NP_389984.1 CDS yonS NC_000964.3 2220335 2220946 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoprotein complement(2220335..2220946) Bacillus subtilis subsp. subtilis str. 168 939171 NP_389985.1 CDS yonR NC_000964.3 2221061 2221387 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator complement(2221061..2221387) Bacillus subtilis subsp. subtilis str. 168 939169 NP_389986.1 CDS yonP NC_000964.3 2222340 2222534 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2222340..2222534 Bacillus subtilis subsp. subtilis str. 168 939168 NP_389987.1 CDS yonO NC_000964.3 2222574 2225093 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2222574..2225093 Bacillus subtilis subsp. subtilis str. 168 939167 NP_389988.1 CDS yonN NC_000964.3 2225337 2225615 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein HU 2 2225337..2225615 Bacillus subtilis subsp. subtilis str. 168 939170 NP_389989.1 CDS yonK NC_000964.3 2227297 2227488 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2227297..2227488 Bacillus subtilis subsp. subtilis str. 168 939166 NP_389990.2 CDS yonJ NC_000964.3 2227505 2228722 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2227505..2228722 Bacillus subtilis subsp. subtilis str. 168 939163 NP_389991.1 CDS yonI NC_000964.3 2228756 2229166 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2228756..2229166) Bacillus subtilis subsp. subtilis str. 168 939164 NP_389992.1 CDS yonH NC_000964.3 2229385 2229885 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2229385..2229885 Bacillus subtilis subsp. subtilis str. 168 939160 NP_389993.1 CDS yonG NC_000964.3 2229988 2230908 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2229988..2230908 Bacillus subtilis subsp. subtilis str. 168 939165 NP_389994.1 CDS yonF NC_000964.3 2230895 2232664 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774886; Product type pe : enzyme; hypothetical protein 2230895..2232664 Bacillus subtilis subsp. subtilis str. 168 939161 NP_389995.1 CDS yonE NC_000964.3 2232682 2234202 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2232682..2234202 Bacillus subtilis subsp. subtilis str. 168 939162 NP_389996.1 CDS yonD NC_000964.3 2234233 2235669 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2234233..2235669 Bacillus subtilis subsp. subtilis str. 168 939159 NP_389997.1 CDS yonC NC_000964.3 2235694 2236230 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2235694..2236230 Bacillus subtilis subsp. subtilis str. 168 939157 NP_389998.1 CDS yonB NC_000964.3 2236269 2237285 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2236269..2237285 Bacillus subtilis subsp. subtilis str. 168 939155 NP_389999.1 CDS yonA NC_000964.3 2237321 2237791 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2237321..2237791 Bacillus subtilis subsp. subtilis str. 168 939158 NP_390000.1 CDS yomZ NC_000964.3 2237806 2238201 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2237806..2238201 Bacillus subtilis subsp. subtilis str. 168 939156 NP_390001.1 CDS yomY NC_000964.3 2238198 2238452 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2238198..2238452 Bacillus subtilis subsp. subtilis str. 168 939154 NP_390002.1 CDS yomX NC_000964.3 2238436 2239086 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2238436..2239086 Bacillus subtilis subsp. subtilis str. 168 939153 NP_390003.1 CDS yomW NC_000964.3 2239083 2239589 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2239083..2239589 Bacillus subtilis subsp. subtilis str. 168 939150 NP_390004.1 CDS yomV NC_000964.3 2239586 2240296 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2239586..2240296 Bacillus subtilis subsp. subtilis str. 168 939149 NP_390005.1 CDS yomU NC_000964.3 2240339 2241136 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2240339..2241136 Bacillus subtilis subsp. subtilis str. 168 939146 YP_003097751.1 CDS youA NC_000964.3 2241154 2241765 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2241154..2241765 Bacillus subtilis subsp. subtilis str. 168 8302922 NP_390006.1 CDS yomT NC_000964.3 2241765 2241992 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2241765..2241992 Bacillus subtilis subsp. subtilis str. 168 939151 NP_390007.1 CDS yomS NC_000964.3 2242056 2242412 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2242056..2242412 Bacillus subtilis subsp. subtilis str. 168 939152 NP_390008.1 CDS yomR NC_000964.3 2242414 2243631 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2242414..2243631 Bacillus subtilis subsp. subtilis str. 168 939147 NP_390009.1 CDS yomQ NC_000964.3 2243642 2243992 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2243642..2243992 Bacillus subtilis subsp. subtilis str. 168 939142 NP_390010.1 CDS yomP NC_000964.3 2243989 2244180 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2243989..2244180 Bacillus subtilis subsp. subtilis str. 168 939148 NP_390011.1 CDS yomO NC_000964.3 2244230 2244730 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2244230..2244730 Bacillus subtilis subsp. subtilis str. 168 939140 NP_390012.1 CDS yomN NC_000964.3 2244714 2245133 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2244714..2245133 Bacillus subtilis subsp. subtilis str. 168 939144 NP_390013.1 CDS yomM NC_000964.3 2245147 2246148 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; recombinase-like protein YomM 2245147..2246148 Bacillus subtilis subsp. subtilis str. 168 939145 NP_390014.1 CDS yozP NC_000964.3 2246151 2246480 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2246151..2246480) Bacillus subtilis subsp. subtilis str. 168 939141 NP_390015.1 CDS yomL NC_000964.3 2246656 2247342 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2246656..2247342) Bacillus subtilis subsp. subtilis str. 168 939143 YP_003097752.1 CDS youB NC_000964.3 2247367 2247543 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276; hypothetical protein complement(2247367..2247543) Bacillus subtilis subsp. subtilis str. 168 8303116 NP_390016.1 CDS yomK NC_000964.3 2247889 2248335 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2247889..2248335 Bacillus subtilis subsp. subtilis str. 168 939137 NP_390017.1 CDS yomJ NC_000964.3 2248417 2249100 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; membrane protein 2248417..2249100 Bacillus subtilis subsp. subtilis str. 168 939133 NP_390018.2 CDS yomI NC_000964.3 2249154 2256011 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931330; Product type h: extrachromosomal origin; transglycosylase YomI 2249154..2256011 Bacillus subtilis subsp. subtilis str. 168 939138 NP_390019.1 CDS yomH NC_000964.3 2256062 2256820 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2256062..2256820 Bacillus subtilis subsp. subtilis str. 168 939139 NP_390020.1 CDS yomG NC_000964.3 2256832 2259459 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; hypothetical protein 2256832..2259459 Bacillus subtilis subsp. subtilis str. 168 939135 NP_390021.1 CDS yomF NC_000964.3 2259475 2260296 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2259475..2260296 Bacillus subtilis subsp. subtilis str. 168 939134 NP_390022.1 CDS yomE NC_000964.3 2260333 2262267 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2260333..2262267 Bacillus subtilis subsp. subtilis str. 168 939136 NP_390023.1 CDS yomD NC_000964.3 2262437 2263261 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2262437..2263261 Bacillus subtilis subsp. subtilis str. 168 939131 NP_390024.1 CDS blyA NC_000964.3 2263489 2264592 D Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase BlyA 2263489..2264592 Bacillus subtilis subsp. subtilis str. 168 939130 NP_390025.1 CDS bhlA NC_000964.3 2264680 2264892 D Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; holin BhlA 2264680..2264892 Bacillus subtilis subsp. subtilis str. 168 939132 NP_390026.1 CDS bhlB NC_000964.3 2264903 2265169 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 17322187; Product type h: extrachromosomal origin; holin-like bacteriophage SPbeta protein BhlB 2264903..2265169 Bacillus subtilis subsp. subtilis str. 168 939127 NP_390027.1 CDS bdbB NC_000964.3 2265225 2265671 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16850406; Product type h: extrachromosomal origin; disulfide bond formation protein B complement(2265225..2265671) Bacillus subtilis subsp. subtilis str. 168 939128 NP_390028.1 CDS yolJ NC_000964.3 2265668 2266936 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pe : enzyme; glycosyltransferase SunS complement(2265668..2266936) Bacillus subtilis subsp. subtilis str. 168 939123 NP_390029.1 CDS bdbA NC_000964.3 2266936 2267349 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949; Product type h: extrachromosomal origin; disulfide bond formation protein A complement(2266936..2267349) Bacillus subtilis subsp. subtilis str. 168 939129 NP_390030.1 CDS sunT NC_000964.3 2267346 2269463 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type t: transporter; sublancin-168-processing and transport ATP-binding protein SunT complement(2267346..2269463) Bacillus subtilis subsp. subtilis str. 168 939124 NP_390031.1 CDS sunA NC_000964.3 2269521 2269691 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type h: extrachromosomal origin; bacteriocin sublancin-168 complement(2269521..2269691) Bacillus subtilis subsp. subtilis str. 168 939121 NP_390032.1 CDS sunI NC_000964.3 2269988 2270305 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 19047653; Product type cp: cell process; hypothetical protein complement(2269988..2270305) Bacillus subtilis subsp. subtilis str. 168 939125 NP_390033.2 CDS uvrX NC_000964.3 2270407 2271657 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12137951, 12644484; Product type e : enzyme; UV-damage repair protein UvrX complement(2270407..2271657) Bacillus subtilis subsp. subtilis str. 168 939122 NP_390034.1 CDS yolD NC_000964.3 2271650 2271982 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951; hypothetical protein complement(2271650..2271982) Bacillus subtilis subsp. subtilis str. 168 939126 NP_390035.1 CDS yolC NC_000964.3 2272156 2272491 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; hypothetical protein 2272156..2272491 Bacillus subtilis subsp. subtilis str. 168 939120 NP_390036.1 CDS yolB NC_000964.3 2272534 2272890 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2272534..2272890) Bacillus subtilis subsp. subtilis str. 168 939119 NP_390037.1 CDS yolA NC_000964.3 2272896 2273363 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; hypothetical protein complement(2272896..2273363) Bacillus subtilis subsp. subtilis str. 168 939117 NP_390038.1 CDS yokL NC_000964.3 2273989 2274522 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YokL complement(2273989..2274522) Bacillus subtilis subsp. subtilis str. 168 939118 NP_390039.1 CDS yokK NC_000964.3 2274558 2275136 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2274558..2275136) Bacillus subtilis subsp. subtilis str. 168 939116 NP_390040.1 CDS yokJ NC_000964.3 2275200 2275697 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2275200..2275697) Bacillus subtilis subsp. subtilis str. 168 939114 NP_390041.2 CDS yokI NC_000964.3 2275706 2277421 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2275706..2277421) Bacillus subtilis subsp. subtilis str. 168 939115 NP_390042.1 CDS yokH NC_000964.3 2277521 2278078 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2277521..2278078) Bacillus subtilis subsp. subtilis str. 168 939111 NP_390043.1 CDS yokG NC_000964.3 2278602 2279675 R Evidence 4: Homologs of previously reported genes of unknown function; pesticidal crystal protein-like YokG complement(2278602..2279675) Bacillus subtilis subsp. subtilis str. 168 939112 NP_390044.1 CDS yokF NC_000964.3 2279977 2280867 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type h: extrachromosomal origin; endonuclease 2279977..2280867 Bacillus subtilis subsp. subtilis str. 168 939113 NP_390045.1 CDS yokE NC_000964.3 2280881 2281363 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2280881..2281363 Bacillus subtilis subsp. subtilis str. 168 939108 NP_390046.1 CDS yokD NC_000964.3 2281667 2282485 D Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; aminoglycoside N(3')-acetyltransferase-like protein YokD 2281667..2282485 Bacillus subtilis subsp. subtilis str. 168 939106 NP_390047.1 CDS yokC NC_000964.3 2283136 2283651 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10376821; hypothetical protein complement(2283136..2283651) Bacillus subtilis subsp. subtilis str. 168 939109 NP_390048.1 CDS yokB NC_000964.3 2283858 2284568 R Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; lipoprotein complement(2283858..2284568) Bacillus subtilis subsp. subtilis str. 168 939110 NP_390049.1 CDS yokA NC_000964.3 2284771 2286408 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821, 401505; Product type pe: enzyme; resolvase homolog YokA 2284771..2286408 Bacillus subtilis subsp. subtilis str. 168 939105 NP_390051.1 CDS yppQ NC_000964.3 2287097 2287528 R this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; peptide methionine sulfoxide reductase MsrB complement(2287097..2287528) Bacillus subtilis subsp. subtilis str. 168 939102 NP_390052.1 CDS msrA NC_000964.3 2287529 2288062 R this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; peptide methionine sulfoxide reductase MsrA complement(2287529..2288062) Bacillus subtilis subsp. subtilis str. 168 939099 NP_390053.1 CDS ypoP NC_000964.3 2288194 2288619 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809700, 9571784; Product type pr: regulator; MarR family transcriptional regulator 2288194..2288619 Bacillus subtilis subsp. subtilis str. 168 939103 NP_390054.1 CDS dinF NC_000964.3 2288669 2290006 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11583854, 15849754, 16850406; Product type t : transporter; multidrug resistance protein complement(2288669..2290006) Bacillus subtilis subsp. subtilis str. 168 939104 NP_390055.1 CDS ypmT NC_000964.3 2290078 2290272 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2290078..2290272) Bacillus subtilis subsp. subtilis str. 168 939101 NP_390056.1 CDS ypmS NC_000964.3 2290285 2290848 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2290285..2290848) Bacillus subtilis subsp. subtilis str. 168 939100 NP_390057.1 CDS ypmR NC_000964.3 2290858 2291625 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2290858..2291625) Bacillus subtilis subsp. subtilis str. 168 939097 NP_390058.2 CDS scuA NC_000964.3 2291703 2292284 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680962, 14766920, 16305244, 19027886, 10837475; Product type f: factor; SCO1 protein homolog complement(2291703..2292284) Bacillus subtilis subsp. subtilis str. 168 939098 NP_390059.1 CDS ypmP NC_000964.3 2292432 2292683 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15060025; hypothetical protein complement(2292432..2292683) Bacillus subtilis subsp. subtilis str. 168 939096 NP_390060.1 CDS ilvA NC_000964.3 2292769 2294037 R catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase complement(2292769..2294037) Bacillus subtilis subsp. subtilis str. 168 939093 NP_390061.1 CDS yplP NC_000964.3 2294286 2295281 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399512, 16585774; Product type r: regulator; sigma L-dependent transcriptional regulator YplP 2294286..2295281 Bacillus subtilis subsp. subtilis str. 168 939094 NP_390062.1 CDS yplQ NC_000964.3 2295302 2295943 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16585774, 16850406; Product type pe: enzyme; hemolysin-3 homolog 2295302..2295943 Bacillus subtilis subsp. subtilis str. 168 939095 NP_390063.2 CDS ypkP NC_000964.3 2295982 2296602 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2295982..2296602) Bacillus subtilis subsp. subtilis str. 168 939090 NP_390064.1 CDS dfrA NC_000964.3 2296603 2297109 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10574451, 12682299, 2840350, 3918568; Product type e: enzyme; dihydrofolate reductase complement(2296603..2297109) Bacillus subtilis subsp. subtilis str. 168 939091 NP_390065.1 CDS thyA NC_000964.3 2297106 2297900 R ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase complement(2297106..2297900) Bacillus subtilis subsp. subtilis str. 168 939092 NP_390066.1 CDS ypjQ NC_000964.3 2297984 2298517 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8534098; Product type pe : enzyme; hypothetical protein complement(2297984..2298517) Bacillus subtilis subsp. subtilis str. 168 939087 NP_390067.1 CDS ypjP NC_000964.3 2298535 2299146 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2298535..2299146) Bacillus subtilis subsp. subtilis str. 168 939089 NP_390068.2 CDS ypiP NC_000964.3 2299406 2300179 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2299406..2300179) Bacillus subtilis subsp. subtilis str. 168 939088 NP_390069.1 CDS yphP NC_000964.3 2300221 2300655 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2300221..2300655) Bacillus subtilis subsp. subtilis str. 168 939085 NP_390070.2 CDS ilvD NC_000964.3 2300762 2302438 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(2300762..2302438) Bacillus subtilis subsp. subtilis str. 168 939084 NP_390071.1 CDS ypgR NC_000964.3 2302727 2303860 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2302727..2303860) Bacillus subtilis subsp. subtilis str. 168 939082 NP_390072.1 CDS ypgQ NC_000964.3 2303920 2304537 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2303920..2304537) Bacillus subtilis subsp. subtilis str. 168 939080 NP_390073.1 CDS bsaA NC_000964.3 2304553 2305035 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871, 14617062; Product type pe: enzyme; glutathione peroxidase homolog BsaA complement(2304553..2305035) Bacillus subtilis subsp. subtilis str. 168 939086 NP_390074.2 CDS metA NC_000964.3 2305378 2306283 D catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 2305378..2306283 Bacillus subtilis subsp. subtilis str. 168 939083 NP_390075.1 CDS ugtP NC_000964.3 2306514 2307662 D processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids; processive diacylglycerol glucosyltransferase 2306514..2307662 Bacillus subtilis subsp. subtilis str. 168 939081 NP_390076.1 CDS cspD NC_000964.3 2307905 2308105 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840, 9920884; Product type f: factor; cold shock protein CspD 2307905..2308105 Bacillus subtilis subsp. subtilis str. 168 939079 NP_390077.1 CDS degR NC_000964.3 2308157 2308339 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16625836; Product type f: factor; regulatory protein DegR complement(2308157..2308339) Bacillus subtilis subsp. subtilis str. 168 939076 NP_390078.1 CDS ypzA NC_000964.3 2308495 2308764 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2308495..2308764 Bacillus subtilis subsp. subtilis str. 168 939078 NP_390079.1 CDS ypeQ NC_000964.3 2308792 2308974 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2308792..2308974) Bacillus subtilis subsp. subtilis str. 168 939077 NP_390080.2 CDS ypeP NC_000964.3 2308967 2309647 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2308967..2309647) Bacillus subtilis subsp. subtilis str. 168 939073 NP_390081.1 CDS ypdP NC_000964.3 2309730 2310419 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2309730..2310419 Bacillus subtilis subsp. subtilis str. 168 939075 NP_390082.1 CDS ypdQ NC_000964.3 2310419 2310817 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9888800; 14.7 kDa ribonuclease H-like protein 2310419..2310817 Bacillus subtilis subsp. subtilis str. 168 939074 YP_054584.1 CDS sspL NC_000964.3 2310859 2310987 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type cp: cell process; small acid-soluble spore protein L 2310859..2310987 Bacillus subtilis subsp. subtilis str. 168 2914255 NP_390083.1 CDS exoA NC_000964.3 2310995 2311885 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16045613, 17038322, 17905985; Product type e: enzyme; 5'-3' exonuclease complement(2310995..2311885) Bacillus subtilis subsp. subtilis str. 168 939070 YP_003097753.1 CDS ypzF NC_000964.3 2311986 2312132 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2311986..2312132) Bacillus subtilis subsp. subtilis str. 168 8302979 NP_390084.1 CDS ypbS NC_000964.3 2312207 2312464 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2312207..2312464) Bacillus subtilis subsp. subtilis str. 168 939067 NP_390085.1 CDS ypbR NC_000964.3 2312529 2316110 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2312529..2316110) Bacillus subtilis subsp. subtilis str. 168 939071 NP_390086.1 CDS ypbQ NC_000964.3 2316446 2316952 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406, 7726551, 8396117; Product type pe: enzyme; hypothetical protein complement(2316446..2316952) Bacillus subtilis subsp. subtilis str. 168 939072 NP_390087.1 CDS bcsA NC_000964.3 2316956 2318053 R Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; chalcone synthase complement(2316956..2318053) Bacillus subtilis subsp. subtilis str. 168 939069 NP_390088.1 CDS pbuX NC_000964.3 2318127 2319443 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923093, 15549109, 15849754, 16850406; Product type t: transporter; xanthine permease complement(2318127..2319443) Bacillus subtilis subsp. subtilis str. 168 939068 NP_390089.1 CDS xpt NC_000964.3 2319440 2320024 R Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase complement(2319440..2320024) Bacillus subtilis subsp. subtilis str. 168 939064 NP_390090.1 CDS ypwA NC_000964.3 2320355 2321860 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7765282; Product type e: enzyme; metalloprotease YpwA complement(2320355..2321860) Bacillus subtilis subsp. subtilis str. 168 939061 NP_390091.1 CDS kdgT NC_000964.3 2321972 2322964 R transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease complement(2321972..2322964) Bacillus subtilis subsp. subtilis str. 168 939065 NP_390092.1 CDS kdgA NC_000964.3 2323009 2323599 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 9846747; Product type e: enzyme; KHG/KDPG aldolase complement(2323009..2323599) Bacillus subtilis subsp. subtilis str. 168 939066 NP_390093.1 CDS kdgK NC_000964.3 2323601 2324575 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 15039578, 9846747; Product type e : enzyme; 2-dehydro-3-deoxygluconokinase complement(2323601..2324575) Bacillus subtilis subsp. subtilis str. 168 939058 NP_390094.1 CDS kdgR NC_000964.3 2324613 2325632 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311, 17322190, 9846747; Product type r: regulator; LacI family transcriptional regulator complement(2324613..2325632) Bacillus subtilis subsp. subtilis str. 168 939063 NP_390095.1 CDS kduI NC_000964.3 2325854 2326681 D 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 4-deoxy-l-threo-5-hexosulose-uronate ketol-isomerase 2325854..2326681 Bacillus subtilis subsp. subtilis str. 168 939062 NP_390096.1 CDS kduD NC_000964.3 2326683 2327447 D Involved in the metabolism of 2-deoxyglucose; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase 2326683..2327447 Bacillus subtilis subsp. subtilis str. 168 939059 NP_390097.1 CDS ypvA NC_000964.3 2327488 2329413 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8385320; Product type pe : enzyme; ATP-dependent helicase YpvA complement(2327488..2329413) Bacillus subtilis subsp. subtilis str. 168 939060 NP_390098.1 CDS yptA NC_000964.3 2329515 2329706 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2329515..2329706) Bacillus subtilis subsp. subtilis str. 168 939055 YP_003097754.1 CDS ypzG NC_000964.3 2329870 2330022 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2329870..2330022 Bacillus subtilis subsp. subtilis str. 168 8303061 NP_390099.1 CDS ypsC NC_000964.3 2330075 2331232 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA methyltransferase YpsC complement(2330075..2331232) Bacillus subtilis subsp. subtilis str. 168 939057 NP_390100.1 CDS ypsB NC_000964.3 2331779 2332075 R GpsB; guiding PBP1 shuttling; similar to DivIVA; cell cycle protein GpsB complement(2331779..2332075) Bacillus subtilis subsp. subtilis str. 168 939054 NP_390101.2 CDS ypsA NC_000964.3 2332153 2332782 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2332153..2332782) Bacillus subtilis subsp. subtilis str. 168 939056 NP_390102.1 CDS cotD NC_000964.3 2332784 2333011 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10075739, 10400595, 1518043, 1691789, 2821284; Product type cp: cell process; spore coat protein D complement(2332784..2333011) Bacillus subtilis subsp. subtilis str. 168 939051 NP_390103.1 CDS yprB NC_000964.3 2333324 2334565 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2333324..2334565) Bacillus subtilis subsp. subtilis str. 168 939050 NP_390104.1 CDS yprA NC_000964.3 2334581 2336830 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YprA complement(2334581..2336830) Bacillus subtilis subsp. subtilis str. 168 939052 NP_390105.1 CDS ypqE NC_000964.3 2336933 2337439 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10627040; Product type pe : enzyme; PTS system transporter subunit IIA YpqE complement(2336933..2337439) Bacillus subtilis subsp. subtilis str. 168 939046 NP_390106.1 CDS ypqA NC_000964.3 2337577 2337996 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2337577..2337996 Bacillus subtilis subsp. subtilis str. 168 939048 NP_390107.1 CDS yppG NC_000964.3 2338017 2338394 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2338017..2338394) Bacillus subtilis subsp. subtilis str. 168 939049 NP_390108.1 CDS yppF NC_000964.3 2338582 2338770 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2338582..2338770 Bacillus subtilis subsp. subtilis str. 168 939045 NP_390109.1 CDS yppE NC_000964.3 2338809 2339180 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2338809..2339180) Bacillus subtilis subsp. subtilis str. 168 939047 NP_390110.1 CDS yppD NC_000964.3 2339226 2339471 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15687200; hypothetical protein complement(2339226..2339471) Bacillus subtilis subsp. subtilis str. 168 939042 YP_054585.1 CDS sspM NC_000964.3 2339670 2339774 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362; Product type cp: cell process; small acid-soluble spore protein M 2339670..2339774 Bacillus subtilis subsp. subtilis str. 168 2914288 NP_390111.1 CDS yppC NC_000964.3 2339799 2340761 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2339799..2340761) Bacillus subtilis subsp. subtilis str. 168 939043 NP_390112.1 CDS recU NC_000964.3 2340802 2341422 D functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; holliday junction resolvase RecU 2340802..2341422 Bacillus subtilis subsp. subtilis str. 168 939039 NP_390113.1 CDS ponA NC_000964.3 2341444 2344188 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10322023, 10692371, 12562814, 15262952; Product type e: enzyme; penicillin-binding protein 1A/1B 2341444..2344188 Bacillus subtilis subsp. subtilis str. 168 939044 NP_390114.1 CDS ypoC NC_000964.3 2344264 2344758 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2344264..2344758) Bacillus subtilis subsp. subtilis str. 168 939041 NP_390115.1 CDS nth NC_000964.3 2344755 2345414 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11160880, 12682299, 9808040; Product type e : enzyme; endonuclease III complement(2344755..2345414) Bacillus subtilis subsp. subtilis str. 168 939036 NP_390116.1 CDS dnaD NC_000964.3 2345433 2346131 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15556628, 15686560, 16002087, 16677303, 16855238, 17277452, 18206906; Product type f : factor; DNA replication protein DnaD complement(2345433..2346131) Bacillus subtilis subsp. subtilis str. 168 939040 NP_390117.1 CDS asnC NC_000964.3 2346224 2347516 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparagine--tRNA ligase complement(2346224..2347516) Bacillus subtilis subsp. subtilis str. 168 939038 NP_390118.1 CDS aspB NC_000964.3 2347660 2348841 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(2347660..2348841) Bacillus subtilis subsp. subtilis str. 168 939037 NP_390119.1 CDS ypmB NC_000964.3 2348864 2349349 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2348864..2349349) Bacillus subtilis subsp. subtilis str. 168 939035 NP_390120.1 CDS ypmA NC_000964.3 2349358 2349528 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2349358..2349528) Bacillus subtilis subsp. subtilis str. 168 939034 NP_390121.1 CDS dinG NC_000964.3 2349671 2352466 R unwinds DNA; ATP-dependent helicase DinG homolog complement(2349671..2352466) Bacillus subtilis subsp. subtilis str. 168 939031 NP_390122.1 CDS panD NC_000964.3 2352592 2352975 R Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate 1-decarboxylase complement(2352592..2352975) Bacillus subtilis subsp. subtilis str. 168 939033 NP_390123.1 CDS panC NC_000964.3 2352977 2353837 R catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantothenate synthetase complement(2352977..2353837) Bacillus subtilis subsp. subtilis str. 168 939030 NP_390124.1 CDS panB NC_000964.3 2353839 2354672 R catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase complement(2353839..2354672) Bacillus subtilis subsp. subtilis str. 168 939032 NP_390125.1 CDS birA NC_000964.3 2354918 2355895 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12368242, 15459338; Product type e: enzyme; bifunctional protein BirA complement(2354918..2355895) Bacillus subtilis subsp. subtilis str. 168 939028 NP_390126.1 CDS cca NC_000964.3 2355880 2357073 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; CCA-adding enzyme complement(2355880..2357073) Bacillus subtilis subsp. subtilis str. 168 939025 NP_390127.1 CDS ypjH NC_000964.3 2357078 2358211 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751541; Product type pe : enzyme; glycosyltransferase YpjH complement(2357078..2358211) Bacillus subtilis subsp. subtilis str. 168 939029 NP_390128.2 CDS ypjG NC_000964.3 2358208 2358918 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11004195; deacetylase YpjG complement(2358208..2358918) Bacillus subtilis subsp. subtilis str. 168 939026 NP_390129.1 CDS mgsA NC_000964.3 2358911 2359324 R catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase complement(2358911..2359324) Bacillus subtilis subsp. subtilis str. 168 939027 NP_390130.1 CDS dapB NC_000964.3 2359340 2360143 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; 4-hydroxy-tetrahydrodipicolinate reductase complement(2359340..2360143) Bacillus subtilis subsp. subtilis str. 168 939024 NP_390131.1 CDS ypjD NC_000964.3 2360155 2360490 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16390452; Product type e: enzyme; hypothetical protein complement(2360155..2360490) Bacillus subtilis subsp. subtilis str. 168 939022 NP_390132.2 CDS ypjC NC_000964.3 2360630 2361502 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2360630..2361502 Bacillus subtilis subsp. subtilis str. 168 939023 NP_390133.1 CDS ypjB NC_000964.3 2361544 2362338 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922; Product type m: membrane component; hypothetical protein complement(2361544..2362338) Bacillus subtilis subsp. subtilis str. 168 939020 NP_390134.1 CDS ypjA NC_000964.3 2362407 2362964 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2362407..2362964) Bacillus subtilis subsp. subtilis str. 168 939018 NP_390135.1 CDS qcrC NC_000964.3 2363111 2363878 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme; menaquinol-cytochrome c reductase cytochrome b/c subunit complement(2363111..2363878) Bacillus subtilis subsp. subtilis str. 168 939021 NP_390136.1 CDS qcrB NC_000964.3 2363913 2364587 R electron transport protein; menaquinol-cytochrome c reductase cytochrome b subunit complement(2363913..2364587) Bacillus subtilis subsp. subtilis str. 168 939019 NP_390137.1 CDS qcrA NC_000964.3 2364589 2365092 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme; menaquinol-cytochrome c reductase iron-sulfur subunit complement(2364589..2365092) Bacillus subtilis subsp. subtilis str. 168 939017 NP_390138.1 CDS ypiF NC_000964.3 2365235 2365681 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2365235..2365681) Bacillus subtilis subsp. subtilis str. 168 939015 NP_390139.1 CDS ypiB NC_000964.3 2365736 2366275 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875; hypothetical protein complement(2365736..2366275) Bacillus subtilis subsp. subtilis str. 168 939016 NP_390140.1 CDS ypiA NC_000964.3 2366347 2367618 R Evidence 4: Homologs of previously reported genes of unknown function; TPR repeat-containing protein YpiA complement(2366347..2367618) Bacillus subtilis subsp. subtilis str. 168 939012 NP_390141.1 CDS aroE NC_000964.3 2367954 2369240 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(2367954..2369240) Bacillus subtilis subsp. subtilis str. 168 939014 NP_390142.1 CDS tyrA NC_000964.3 2369251 2370366 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(2369251..2370366) Bacillus subtilis subsp. subtilis str. 168 939013 NP_390143.2 CDS hisC NC_000964.3 2370415 2371497 R catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase complement(2370415..2371497) Bacillus subtilis subsp. subtilis str. 168 939009 NP_390144.1 CDS trpA NC_000964.3 2371508 2372311 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase alpha chain complement(2371508..2372311) Bacillus subtilis subsp. subtilis str. 168 939011 NP_390145.2 CDS trpB NC_000964.3 2372304 2373506 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase beta chain complement(2372304..2373506) Bacillus subtilis subsp. subtilis str. 168 939010 NP_390146.3 CDS trpF NC_000964.3 2373487 2374134 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(2373487..2374134) Bacillus subtilis subsp. subtilis str. 168 939006 NP_390147.3 CDS trpC NC_000964.3 2374139 2374888 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase complement(2374139..2374888) Bacillus subtilis subsp. subtilis str. 168 939004 NP_390148.2 CDS trpD NC_000964.3 2374881 2375897 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(2374881..2375897) Bacillus subtilis subsp. subtilis str. 168 939007 NP_390149.1 CDS trpE NC_000964.3 2375869 2377416 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component 1 complement(2375869..2377416) Bacillus subtilis subsp. subtilis str. 168 939008 NP_390150.1 CDS aroH NC_000964.3 2377632 2378015 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10818343, 15865424, 16060652, 2105742, 8378335, 9384560; Product type e : enzyme; chorismate mutase AroH complement(2377632..2378015) Bacillus subtilis subsp. subtilis str. 168 939005 NP_390151.1 CDS aroB NC_000964.3 2378012 2379100 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(2378012..2379100) Bacillus subtilis subsp. subtilis str. 168 939001 NP_390152.3 CDS aroF NC_000964.3 2379100 2380272 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(2379100..2380272) Bacillus subtilis subsp. subtilis str. 168 939000 NP_390153.2 CDS cheR NC_000964.3 2380347 2381117 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 15544802, 7635819, 7893679, 8244966; Product type e: enzyme; chemotaxis protein methyltransferase complement(2380347..2381117) Bacillus subtilis subsp. subtilis str. 168 939003 NP_390154.1 CDS ndk NC_000964.3 2381354 2381803 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(2381354..2381803) Bacillus subtilis subsp. subtilis str. 168 938997 NP_390155.1 CDS hepT NC_000964.3 2381919 2382965 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme; heptaprenyl diphosphate synthase component 2 complement(2381919..2382965) Bacillus subtilis subsp. subtilis str. 168 939002 NP_390156.1 CDS ubiE NC_000964.3 2382907 2383608 R Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; demethylmenaquinone methyltransferase complement(2382907..2383608) Bacillus subtilis subsp. subtilis str. 168 938999 NP_390157.1 CDS hepS NC_000964.3 2383615 2384370 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme; heptaprenyl diphosphate synthase component 1 complement(2383615..2384370) Bacillus subtilis subsp. subtilis str. 168 938998 NP_390158.1 CDS mtrB NC_000964.3 2384534 2384761 R tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination; transcription attenuation protein MtrB complement(2384534..2384761) Bacillus subtilis subsp. subtilis str. 168 938996 NP_390159.1 CDS folE NC_000964.3 2384783 2385355 R involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase 1 complement(2384783..2385355) Bacillus subtilis subsp. subtilis str. 168 938994 NP_390160.1 CDS hbs NC_000964.3 2385543 2385821 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10224127, 10231583, 10715001, 11931565, 1382620, 9106208; Product type f : factor; DNA-binding protein HU 1 complement(2385543..2385821) Bacillus subtilis subsp. subtilis str. 168 938995 NP_390161.1 CDS spoIVA NC_000964.3 2386195 2387673 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160095, 17114257, 17427285; Product type cp: cell process; stage IV sporulation protein A complement(2386195..2387673) Bacillus subtilis subsp. subtilis str. 168 938991 NP_390162.1 CDS yphF NC_000964.3 2387854 2388588 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein complement(2387854..2388588) Bacillus subtilis subsp. subtilis str. 168 938992 NP_390163.1 CDS yphE NC_000964.3 2388610 2388813 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2388610..2388813) Bacillus subtilis subsp. subtilis str. 168 938993 NP_390164.1 CDS gpsA NC_000964.3 2389151 2390188 R catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; glycerol-3-phosphate dehydrogenase complement(2389151..2390188) Bacillus subtilis subsp. subtilis str. 168 938989 NP_390165.1 CDS engA NC_000964.3 2390206 2391516 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTPase Der complement(2390206..2391516) Bacillus subtilis subsp. subtilis str. 168 938988 YP_003097755.1 CDS ypzH NC_000964.3 2391670 2391864 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2391670..2391864) Bacillus subtilis subsp. subtilis str. 168 8303000 NP_390166.1 CDS seaA NC_000964.3 2391861 2392754 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2391861..2392754) Bacillus subtilis subsp. subtilis str. 168 938990 NP_390167.1 CDS yphA NC_000964.3 2392751 2393350 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2392751..2393350) Bacillus subtilis subsp. subtilis str. 168 938987 YP_003097756.1 CDS ypzI NC_000964.3 2393422 2393559 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2393422..2393559 Bacillus subtilis subsp. subtilis str. 168 8303059 NP_390168.3 CDS fni NC_000964.3 2393602 2394651 R catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl-diphosphate delta-isomerase complement(2393602..2394651) Bacillus subtilis subsp. subtilis str. 168 938985 NP_390169.1 CDS rpsA NC_000964.3 2394664 2395812 R in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 homolog complement(2394664..2395812) Bacillus subtilis subsp. subtilis str. 168 938986 NP_390170.1 CDS cmk NC_000964.3 2396045 2396719 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(2396045..2396719) Bacillus subtilis subsp. subtilis str. 168 938982 NP_390171.1 CDS ypfB NC_000964.3 2396798 2396974 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2396798..2396974) Bacillus subtilis subsp. subtilis str. 168 938983 NP_390172.1 CDS dgrA NC_000964.3 2397019 2397672 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16249258; Product type pr : regulator; c-di-GMP receptor protein complement(2397019..2397672) Bacillus subtilis subsp. subtilis str. 168 938984 NP_390173.1 CDS ypeB NC_000964.3 2397765 2399117 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332; Product type cp: cell process; sporulation protein YpeB complement(2397765..2399117) Bacillus subtilis subsp. subtilis str. 168 938981 NP_390174.1 CDS sleB NC_000964.3 2399152 2400069 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332, 16905870, 16907803; Product type cp: cell process; spore cortex-lytic enzyme complement(2399152..2400069) Bacillus subtilis subsp. subtilis str. 168 938979 NP_390175.1 CDS prsW NC_000964.3 2400208 2400864 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16816000, 16850406, 17020587; Product type e: enzyme; protease PrsW complement(2400208..2400864) Bacillus subtilis subsp. subtilis str. 168 938978 NP_390176.2 CDS ypdA NC_000964.3 2400984 2401958 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2400984..2401958) Bacillus subtilis subsp. subtilis str. 168 938977 NP_390177.2 CDS gudB NC_000964.3 2402067 2403350 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18326565, 9829940; Product type e: enzyme; cryptic catabolic NAD-specific glutamate dehydrogenase GudB complement(2402067..2403350) Bacillus subtilis subsp. subtilis str. 168 938975 NP_390178.1 CDS ypbH NC_000964.3 2403506 2404090 R enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adapter protein MecA 2 complement(2403506..2404090) Bacillus subtilis subsp. subtilis str. 168 938980 NP_390179.1 CDS ypbG NC_000964.3 2404249 2405028 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme; hypothetical protein complement(2404249..2405028) Bacillus subtilis subsp. subtilis str. 168 938974 NP_390180.1 CDS ypbF NC_000964.3 2405114 2405557 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2405114..2405557) Bacillus subtilis subsp. subtilis str. 168 938976 NP_390181.1 CDS ypbE NC_000964.3 2405620 2406342 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244; hypothetical protein complement(2405620..2406342) Bacillus subtilis subsp. subtilis str. 168 938971 NP_390182.1 CDS ypbD NC_000964.3 2406293 2406862 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; hypothetical protein complement(2406293..2406862) Bacillus subtilis subsp. subtilis str. 168 938972 NP_390183.1 CDS recQ NC_000964.3 2406922 2408412 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16385024; Product type e: enzyme; ATP-dependent DNA helicase RecS complement(2406922..2408412) Bacillus subtilis subsp. subtilis str. 168 938969 NP_390184.1 CDS ypbB NC_000964.3 2408405 2409463 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2408405..2409463) Bacillus subtilis subsp. subtilis str. 168 938973 NP_390185.1 CDS fer NC_000964.3 2409729 2409977 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12538057; Product type c: carrier; ferredoxin 2409729..2409977 Bacillus subtilis subsp. subtilis str. 168 938968 NP_390186.1 CDS fmnP NC_000964.3 2410017 2410589 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 15849754, 16850406, 17693491; Product type t: transporter; riboflavin transporter FmnP complement(2410017..2410589) Bacillus subtilis subsp. subtilis str. 168 938970 NP_390187.1 CDS ypzE NC_000964.3 2410695 2410859 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2410695..2410859) Bacillus subtilis subsp. subtilis str. 168 938967 NP_390188.2 CDS serA NC_000964.3 2411086 2412663 D catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2411086..2412663 Bacillus subtilis subsp. subtilis str. 168 938964 NP_390189.1 CDS aroD NC_000964.3 2412706 2413473 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(2412706..2413473) Bacillus subtilis subsp. subtilis str. 168 938963 NP_390190.2 CDS rsiX NC_000964.3 2413585 2414691 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10712692, 14762009, 9393439; Product type r: regulator; sigma-X negative effector complement(2413585..2414691) Bacillus subtilis subsp. subtilis str. 168 938959 NP_390191.2 CDS sigX NC_000964.3 2414627 2415211 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance; RNA polymerase sigma factor SigX complement(2414627..2415211) Bacillus subtilis subsp. subtilis str. 168 938966 NP_390192.1 CDS resE NC_000964.3 2415415 2417184 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11222591, 14996800, 16825793, 16885456, 17189364, 17322317; Product type rc : receptor; sensor histidine kinase complement(2415415..2417184) Bacillus subtilis subsp. subtilis str. 168 938965 NP_390193.2 CDS resD NC_000964.3 2417181 2417903 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 15375128, 16825793, 16885456, 17322317; Product type r : regulator; transcriptional regulatory protein ResD complement(2417181..2417903) Bacillus subtilis subsp. subtilis str. 168 938960 NP_390194.2 CDS resC NC_000964.3 2417984 2419159 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 15849754, 16850406; Product type f: factor; cytochrome c biogenesis protein ResC complement(2417984..2419159) Bacillus subtilis subsp. subtilis str. 168 938962 NP_390195.1 CDS resB NC_000964.3 2419179 2420807 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 16825793, 9395519; Product type f: factor; cytochrome c biogenesis protein ResB complement(2419179..2420807) Bacillus subtilis subsp. subtilis str. 168 938961 NP_390196.2 CDS resA NC_000964.3 2420804 2421343 R catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c; thiol-disulfide oxidoreductase ResA complement(2420804..2421343) Bacillus subtilis subsp. subtilis str. 168 938958 NP_390197.2 CDS rluB NC_000964.3 2421438 2422172 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9888802; Product type e : enzyme; ribosomal large subunit pseudouridine synthase B complement(2421438..2422172) Bacillus subtilis subsp. subtilis str. 168 938955 NP_390198.2 CDS spmB NC_000964.3 2422264 2422800 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process; spore maturation protein B complement(2422264..2422800) Bacillus subtilis subsp. subtilis str. 168 938957 NP_390199.1 CDS spmA NC_000964.3 2422805 2423395 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process; spore maturation protein A complement(2422805..2423395) Bacillus subtilis subsp. subtilis str. 168 938954 NP_390200.1 CDS dacB NC_000964.3 2423383 2424531 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498740, 7642500, 8892816, 9864321; Product type cp: cell process; D-alanyl-D-alanine carboxypeptidase DacB complement(2423383..2424531) Bacillus subtilis subsp. subtilis str. 168 938953 NP_390201.1 CDS ypuI NC_000964.3 2424654 2425193 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423; hypothetical protein complement(2424654..2425193) Bacillus subtilis subsp. subtilis str. 168 938956 NP_390202.1 CDS spcB NC_000964.3 2425248 2425841 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137; Product type f: factor; segregation and condensation protein B complement(2425248..2425841) Bacillus subtilis subsp. subtilis str. 168 938951 NP_390203.1 CDS scpA NC_000964.3 2425831 2426586 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(2425831..2426586) Bacillus subtilis subsp. subtilis str. 168 938950 NP_390204.1 CDS ypuF NC_000964.3 2426867 2427391 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2426867..2427391 Bacillus subtilis subsp. subtilis str. 168 938952 NP_390205.1 CDS ypzK NC_000964.3 2427405 2427779 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466513; Product type pe : enzyme; riboflavin biosynthesis protein RibT complement(2427405..2427779) Bacillus subtilis subsp. subtilis str. 168 938948 NP_390206.1 CDS ribH NC_000964.3 2427892 2428356 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(2427892..2428356) Bacillus subtilis subsp. subtilis str. 168 938949 NP_390207.1 CDS ribA NC_000964.3 2428389 2429585 R bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; riboflavin biosynthesis protein RibBA complement(2428389..2429585) Bacillus subtilis subsp. subtilis str. 168 938946 NP_390208.1 CDS ribE NC_000964.3 2429600 2430247 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase complement(2429600..2430247) Bacillus subtilis subsp. subtilis str. 168 938947 NP_390209.1 CDS ribD NC_000964.3 2430258 2431343 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 18986985, 9068650; Product type e: enzyme; riboflavin biosynthesis protein RibD complement(2430258..2431343) Bacillus subtilis subsp. subtilis str. 168 938945 NP_390211.1 CDS ypuD NC_000964.3 2431737 2432081 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2431737..2432081) Bacillus subtilis subsp. subtilis str. 168 938943 NP_390212.1 CDS sipS NC_000964.3 2432316 2432870 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15502345, 11004175, 10982814, 9694797, 9823656, 10198007, 10336490; Product type e: enzyme; signal peptidase I S complement(2432316..2432870) Bacillus subtilis subsp. subtilis str. 168 938944 NP_390213.1 CDS ypzC NC_000964.3 2433137 2433373 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2433137..2433373 Bacillus subtilis subsp. subtilis str. 168 938940 YP_003097757.1 CDS ypzJ NC_000964.3 2433316 2433522 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2433316..2433522) Bacillus subtilis subsp. subtilis str. 168 8302956 NP_390215.1 CDS ypuB NC_000964.3 2434143 2434346 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2434143..2434346) Bacillus subtilis subsp. subtilis str. 168 938942 NP_390216.1 CDS ypzD NC_000964.3 2435012 2435224 D Evidence 4: Homologs of previously reported genes of unknown function; spore germination protein-like protein YpzD 2435012..2435224 Bacillus subtilis subsp. subtilis str. 168 938937 NP_390217.1 CDS ppiB NC_000964.3 2435360 2435791 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8639516, 9063446, 9748346; Product type e: enzyme; peptidyl-prolyl cis-trans isomerase complement(2435360..2435791) Bacillus subtilis subsp. subtilis str. 168 938934 NP_390218.1 CDS ypuA NC_000964.3 2436045 2436917 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17434969; Product type pf : factor; hypothetical protein 2436045..2436917 Bacillus subtilis subsp. subtilis str. 168 938939 NP_390219.1 CDS lysA NC_000964.3 2436947 2438266 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14627808, 9044297; Product type e: enzyme; diaminopimelate decarboxylase complement(2436947..2438266) Bacillus subtilis subsp. subtilis str. 168 938931 NP_390220.2 CDS spoVAF NC_000964.3 2438372 2439853 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process; stage V sporulation protein AF complement(2438372..2439853) Bacillus subtilis subsp. subtilis str. 168 938936 YP_003097758.1 CDS spoVAEA NC_000964.3 2439804 2440415 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113, 17573930; Product type cp: cell process; stage V sporulation protein AE complement(2439804..2440415) Bacillus subtilis subsp. subtilis str. 168 8303022 YP_003097759.1 CDS spoVAEB NC_000964.3 2440423 2440773 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17573930; Product type cp: cell process; stage V sporulation protein AEB complement(2440423..2440773) Bacillus subtilis subsp. subtilis str. 168 8303020 NP_390222.1 CDS spoVAD NC_000964.3 2440775 2441791 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process; stage V sporulation protein AD complement(2440775..2441791) Bacillus subtilis subsp. subtilis str. 168 938932 NP_390223.1 CDS spoVAC NC_000964.3 2441804 2442256 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process; stage V sporulation protein AC complement(2441804..2442256) Bacillus subtilis subsp. subtilis str. 168 938733 NP_390224.1 CDS spoVAB NC_000964.3 2442269 2442694 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process; stage V sporulation protein AB complement(2442269..2442694) Bacillus subtilis subsp. subtilis str. 168 938933 NP_390225.2 CDS spoVAA NC_000964.3 2442684 2443304 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3114420; Product type cp: cell process; stage V sporulation protein AA complement(2442684..2443304) Bacillus subtilis subsp. subtilis str. 168 938734 NP_390226.1 CDS sigF NC_000964.3 2443429 2444196 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.; RNA polymerase sigma-F factor complement(2443429..2444196) Bacillus subtilis subsp. subtilis str. 168 938729 NP_390227.1 CDS spoIIAB NC_000964.3 2444208 2444648 R binds to sigma F preventing its association with RNA polymerase during sporulation; anti-sigma F factor complement(2444208..2444648) Bacillus subtilis subsp. subtilis str. 168 938930 NP_390228.1 CDS spoIIAA NC_000964.3 2444645 2444998 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11173484, 15819616, 16824103; Product type cp: cell process; anti-sigma F factor antagonist complement(2444645..2444998) Bacillus subtilis subsp. subtilis str. 168 938730 NP_390229.1 CDS dacF NC_000964.3 2445094 2446263 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8021191, 8936302, 9864321; Product type cp: cell process; D-alanyl-D-alanine carboxypeptidase DacF complement(2445094..2446263) Bacillus subtilis subsp. subtilis str. 168 938732 NP_390230.1 CDS pupG NC_000964.3 2446418 2447233 R catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1 complement(2446418..2447233) Bacillus subtilis subsp. subtilis str. 168 938731 NP_390231.2 CDS drm NC_000964.3 2447246 2448430 R catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase complement(2447246..2448430) Bacillus subtilis subsp. subtilis str. 168 938728 NP_390232.2 CDS xerD NC_000964.3 2448591 2449481 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; tyrosine recombinase XerD complement(2448591..2449481) Bacillus subtilis subsp. subtilis str. 168 938726 YP_003097760.1 CDS yqzK NC_000964.3 2449489 2449716 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(2449489..2449716) Bacillus subtilis subsp. subtilis str. 168 8302907 NP_390233.2 CDS fur NC_000964.3 2449841 2450290 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12374814, 14563870, 15802251, 16672620; Product type r: regulator; ferric uptake regulation protein complement(2449841..2450290) Bacillus subtilis subsp. subtilis str. 168 938727 NP_390234.1 CDS spoIIM NC_000964.3 2450403 2451047 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17376078; Product type cp: cell process; stage II sporulation protein M complement(2450403..2451047) Bacillus subtilis subsp. subtilis str. 168 938723 NP_390235.1 CDS yqkK NC_000964.3 2451148 2451363 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2451148..2451363) Bacillus subtilis subsp. subtilis str. 168 938724 NP_390236.1 CDS mleA NC_000964.3 2451463 2452782 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme; NAD-dependent malic enzyme 1 complement(2451463..2452782) Bacillus subtilis subsp. subtilis str. 168 938725 NP_390237.1 CDS mleN NC_000964.3 2452800 2454206 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10903309, 15849754, 16850406; Product type t: transporter; malate-2H(+)/Na(+)-lactate antiporter complement(2452800..2454206) Bacillus subtilis subsp. subtilis str. 168 938720 NP_390238.2 CDS aspA NC_000964.3 2454347 2455774 R catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase complement(2454347..2455774) Bacillus subtilis subsp. subtilis str. 168 938721 NP_390239.1 CDS ansA NC_000964.3 2455819 2456808 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 1711029; Product type e: enzyme; L-asparaginase 1 complement(2455819..2456808) Bacillus subtilis subsp. subtilis str. 168 938722 NP_390240.1 CDS ansR NC_000964.3 2456990 2457340 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346; Product type r: regulator; XRE family transcriptional regulator 2456990..2457340 Bacillus subtilis subsp. subtilis str. 168 938717 NP_390241.2 CDS yqxK NC_000964.3 2457349 2458512 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2457349..2458512) Bacillus subtilis subsp. subtilis str. 168 938718 NP_390242.1 CDS nudF NC_000964.3 2458509 2459066 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10542272, 17693564; Product type e: enzyme; adp-ribose pyrophosphatase complement(2458509..2459066) Bacillus subtilis subsp. subtilis str. 168 938719 NP_390243.1 CDS yqkF NC_000964.3 2459326 2460246 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15317791, 16242712, 9643546; Product type e: enzyme; oxidoreductase 2459326..2460246 Bacillus subtilis subsp. subtilis str. 168 938714 NP_390244.1 CDS yqkE NC_000964.3 2460278 2460502 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2460278..2460502) Bacillus subtilis subsp. subtilis str. 168 938715 NP_390245.1 CDS yqkD NC_000964.3 2460664 2461581 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2460664..2461581 Bacillus subtilis subsp. subtilis str. 168 938716 NP_390246.1 CDS yqkC NC_000964.3 2461621 2461860 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2461621..2461860) Bacillus subtilis subsp. subtilis str. 168 938711 NP_390247.1 CDS yqkB NC_000964.3 2461873 2462196 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2461873..2462196) Bacillus subtilis subsp. subtilis str. 168 938713 NP_390248.1 CDS yqkA NC_000964.3 2462193 2463224 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2462193..2463224) Bacillus subtilis subsp. subtilis str. 168 938712 NP_390249.1 CDS yqjZ NC_000964.3 2463217 2463561 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein complement(2463217..2463561) Bacillus subtilis subsp. subtilis str. 168 938708 NP_390250.1 CDS yqjY NC_000964.3 2463571 2464041 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein complement(2463571..2464041) Bacillus subtilis subsp. subtilis str. 168 938709 NP_390251.1 CDS yqjX NC_000964.3 2464227 2464565 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951, 16267290; hypothetical protein complement(2464227..2464565) Bacillus subtilis subsp. subtilis str. 168 938710 NP_390252.1 CDS yqjW NC_000964.3 2464562 2465800 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2 complement(2464562..2465800) Bacillus subtilis subsp. subtilis str. 168 938705 NP_390253.1 CDS yqzH NC_000964.3 2465966 2466172 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2465966..2466172 Bacillus subtilis subsp. subtilis str. 168 938707 NP_390254.2 CDS yqjV NC_000964.3 2466721 2467953 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527, 15849754, 16850406; Product type pt: transporter; MFS transporter 2466721..2467953 Bacillus subtilis subsp. subtilis str. 168 938706 NP_390255.1 CDS yqjU NC_000964.3 2467971 2468162 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2467971..2468162 Bacillus subtilis subsp. subtilis str. 168 938702 NP_390256.1 CDS yqjT NC_000964.3 2468159 2468545 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2468159..2468545) Bacillus subtilis subsp. subtilis str. 168 938703 NP_390257.2 CDS coaA NC_000964.3 2468549 2469508 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(2468549..2469508) Bacillus subtilis subsp. subtilis str. 168 938704 NP_390258.2 CDS dsdA NC_000964.3 2469580 2470926 R catalyzes the formation of pyruvate from serine; D-serine dehydratase complement(2469580..2470926) Bacillus subtilis subsp. subtilis str. 168 938700 NP_390259.1 CDS yqjQ NC_000964.3 2471002 2471781 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(2471002..2471781) Bacillus subtilis subsp. subtilis str. 168 938699 NP_390260.1 CDS yqjP NC_000964.3 2471787 2472746 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2471787..2472746) Bacillus subtilis subsp. subtilis str. 168 938701 NP_390261.1 CDS proI NC_000964.3 2473151 2473987 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme; pyrroline-5-carboxylate reductase 2 2473151..2473987 Bacillus subtilis subsp. subtilis str. 168 938697 NP_390262.2 CDS yqjN NC_000964.3 2474028 2475671 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2474028..2475671) Bacillus subtilis subsp. subtilis str. 168 938696 NP_390263.1 CDS yqjM NC_000964.3 2475843 2476859 D catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds; NADPH dehydrogenase 2475843..2476859 Bacillus subtilis subsp. subtilis str. 168 938698 NP_390264.1 CDS yqjL NC_000964.3 2476969 2477730 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme; hypothetical protein 2476969..2477730 Bacillus subtilis subsp. subtilis str. 168 938693 NP_390265.1 CDS yqjK NC_000964.3 2478006 2478929 R member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z complement(2478006..2478929) Bacillus subtilis subsp. subtilis str. 168 938694 NP_390266.2 CDS zwf NC_000964.3 2479156 2480625 D catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2479156..2480625 Bacillus subtilis subsp. subtilis str. 168 938690 NP_390267.2 CDS yqjI NC_000964.3 2480750 2482159 R catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase complement(2480750..2482159) Bacillus subtilis subsp. subtilis str. 168 938695 NP_390268.2 CDS yqjH NC_000964.3 2482269 2483513 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1 complement(2482269..2483513) Bacillus subtilis subsp. subtilis str. 168 938691 YP_054586.1 CDS yqzJ NC_000964.3 2483586 2483873 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2483586..2483873 Bacillus subtilis subsp. subtilis str. 168 2914225 NP_390269.1 CDS yqjG NC_000964.3 2483904 2484731 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; membrane protein insertase MisCB 2483904..2484731 Bacillus subtilis subsp. subtilis str. 168 938692 NP_390270.3 CDS yqjF NC_000964.3 2484911 2485639 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2484911..2485639 Bacillus subtilis subsp. subtilis str. 168 938688 NP_390271.2 CDS yqjE NC_000964.3 2485680 2486795 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2485680..2486795) Bacillus subtilis subsp. subtilis str. 168 938687 NP_390272.2 CDS yqjD NC_000964.3 2486813 2488336 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; propionyl-CoA carboxylase beta chain complement(2486813..2488336) Bacillus subtilis subsp. subtilis str. 168 938685 NP_390273.2 CDS yqjC NC_000964.3 2488329 2488751 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2488329..2488751) Bacillus subtilis subsp. subtilis str. 168 938689 NP_390274.1 CDS yqjB NC_000964.3 2488953 2489483 R Evidence 4: Homologs of previously reported genes of unknown function; L,D-transpeptidase YqjB complement(2488953..2489483) Bacillus subtilis subsp. subtilis str. 168 938684 NP_390275.2 CDS yqjA NC_000964.3 2489535 2490503 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2489535..2490503) Bacillus subtilis subsp. subtilis str. 168 938681 NP_390276.1 CDS artR NC_000964.3 2490574 2491296 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter; arginine transport ATP-binding protein ArtM complement(2490574..2491296) Bacillus subtilis subsp. subtilis str. 168 938686 NP_390277.1 CDS artQ NC_000964.3 2491289 2491948 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15849754, 16850406; Product type t: transporter; arginine transport system permease protein ArtQ complement(2491289..2491948) Bacillus subtilis subsp. subtilis str. 168 938678 NP_390278.1 CDS artP NC_000964.3 2492029 2492796 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter; arginine-binding extracellular protein ArtP complement(2492029..2492796) Bacillus subtilis subsp. subtilis str. 168 938682 NP_390279.1 CDS yqiW NC_000964.3 2493064 2493501 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2493064..2493501) Bacillus subtilis subsp. subtilis str. 168 938683 NP_390280.2 CDS bmrU NC_000964.3 2493662 2494555 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 7961792, 8098708; Product type pe: enzyme; lipid kinase BmrU 2493662..2494555 Bacillus subtilis subsp. subtilis str. 168 938679 NP_390281.2 CDS bmr NC_000964.3 2494656 2495825 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10961951, 11321573, 15849754, 16850406; Product type t : transporter; multidrug resistance protein 2494656..2495825 Bacillus subtilis subsp. subtilis str. 168 938680 NP_390282.2 CDS bmrR NC_000964.3 2495898 2496734 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11201751, 11839496, 12682015, 14985361; Product type r: regulator; MerR family transcriptional regulator 2495898..2496734 Bacillus subtilis subsp. subtilis str. 168 938676 NP_390283.1 CDS bkdB NC_000964.3 2496796 2498070 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex complement(2496796..2498070) Bacillus subtilis subsp. subtilis str. 168 938677 NP_390284.1 CDS bkdAB NC_000964.3 2498093 2499076 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; 2-oxoisovalerate dehydrogenase subunit beta complement(2498093..2499076) Bacillus subtilis subsp. subtilis str. 168 938672 NP_390285.1 CDS bkdAA NC_000964.3 2499090 2500082 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; 2-oxoisovalerate dehydrogenase subunit alpha complement(2499090..2500082) Bacillus subtilis subsp. subtilis str. 168 938674 NP_390286.2 CDS lpdV NC_000964.3 2500104 2501528 R E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase complement(2500104..2501528) Bacillus subtilis subsp. subtilis str. 168 938669 NP_390287.2 CDS buk NC_000964.3 2501549 2502640 R catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase complement(2501549..2502640) Bacillus subtilis subsp. subtilis str. 168 938675 NP_390288.1 CDS bcd NC_000964.3 2502659 2503753 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; leucine dehydrogenase complement(2502659..2503753) Bacillus subtilis subsp. subtilis str. 168 938670 NP_390289.2 CDS ptb NC_000964.3 2503765 2504664 R catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate; phosphate butyryltransferase complement(2503765..2504664) Bacillus subtilis subsp. subtilis str. 168 938671 NP_390290.1 CDS bkdR NC_000964.3 2504789 2506867 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682, 16585774; Product type r: regulator; sigma L-dependent transcriptional regulator YqiR complement(2504789..2506867) Bacillus subtilis subsp. subtilis str. 168 938666 NP_390291.1 CDS yqzF NC_000964.3 2507020 2507256 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2507020..2507256 Bacillus subtilis subsp. subtilis str. 168 938667 NP_390292.1 CDS prpB NC_000964.3 2507298 2508203 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12706720; Product type e: enzyme; methylisocitrate lyase complement(2507298..2508203) Bacillus subtilis subsp. subtilis str. 168 938668 NP_390293.2 CDS prpD NC_000964.3 2508221 2509639 R functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase complement(2508221..2509639) Bacillus subtilis subsp. subtilis str. 168 938663 NP_390294.1 CDS mmgD NC_000964.3 2509654 2510772 R forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration; 2-methylcitrate synthase complement(2509654..2510772) Bacillus subtilis subsp. subtilis str. 168 938665 NP_390295.2 CDS mmgC NC_000964.3 2510806 2511945 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; acyl-CoA dehydrogenase complement(2510806..2511945) Bacillus subtilis subsp. subtilis str. 168 938664 NP_390296.2 CDS mmgB NC_000964.3 2511973 2512836 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8759838; Product type e: enzyme; 3-hydroxybutyryl-CoA dehydrogenase complement(2511973..2512836) Bacillus subtilis subsp. subtilis str. 168 938660 NP_390297.1 CDS mmgA NC_000964.3 2512861 2514042 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase complement(2512861..2514042) Bacillus subtilis subsp. subtilis str. 168 938662 NP_390298.2 CDS yqiK NC_000964.3 2514169 2514900 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2514169..2514900) Bacillus subtilis subsp. subtilis str. 168 938661 NP_390299.2 CDS yqiI NC_000964.3 2514979 2515599 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2514979..2515599) Bacillus subtilis subsp. subtilis str. 168 938657 NP_390300.2 CDS yqiH NC_000964.3 2515614 2515907 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein complement(2515614..2515907) Bacillus subtilis subsp. subtilis str. 168 938658 NP_390301.1 CDS yqiG NC_000964.3 2516440 2517558 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADH-dependent flavin oxidoreductase YqiG 2516440..2517558 Bacillus subtilis subsp. subtilis str. 168 938659 NP_390302.1 CDS spo0A NC_000964.3 2518023 2518826 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12406209, 15556029, 15808745, 8504245; Product type r: regulator; stage 0 sporulation protein A complement(2518023..2518826) Bacillus subtilis subsp. subtilis str. 168 938655 NP_390303.2 CDS spoIVB NC_000964.3 2519102 2520382 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12218026, 15292188, 16164552, 16238631, 16818230; Product type cp: cell process; peptidase S55 complement(2519102..2520382) Bacillus subtilis subsp. subtilis str. 168 938654 NP_390304.2 CDS recN NC_000964.3 2520557 2522287 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15186413, 15849320, 16061691, 16385024; Product type f: factor; DNA repair protein RecN complement(2520557..2522287) Bacillus subtilis subsp. subtilis str. 168 938656 NP_390305.1 CDS ahrC NC_000964.3 2522324 2522773 R regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor complement(2522324..2522773) Bacillus subtilis subsp. subtilis str. 168 938653 NP_390306.2 CDS yqxC NC_000964.3 2522871 2523716 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; rRNA methyltransferase YqxC complement(2522871..2523716) Bacillus subtilis subsp. subtilis str. 168 938651 NP_390307.1 CDS dxs NC_000964.3 2523713 2525614 R catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase complement(2523713..2525614) Bacillus subtilis subsp. subtilis str. 168 938609 NP_390308.2 CDS ispA NC_000964.3 2525789 2526679 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17147392, 8755734; Product type e : enzyme; farnesyl diphosphate synthase complement(2525789..2526679) Bacillus subtilis subsp. subtilis str. 168 938652 NP_390309.2 CDS xseB NC_000964.3 2526669 2526923 R catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease 7 small subunit complement(2526669..2526923) Bacillus subtilis subsp. subtilis str. 168 938649 NP_390310.2 CDS xseA NC_000964.3 2526920 2528266 R bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease 7 large subunit complement(2526920..2528266) Bacillus subtilis subsp. subtilis str. 168 938650 NP_390311.1 CDS folD NC_000964.3 2528404 2529255 R catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional protein FolD complement(2528404..2529255) Bacillus subtilis subsp. subtilis str. 168 938602 NP_390312.2 CDS nusB NC_000964.3 2529267 2529662 R Regulates rRNA biosynthesis by transcriptional antitermination; N utilization substance protein B homolog complement(2529267..2529662) Bacillus subtilis subsp. subtilis str. 168 938606 NP_390313.2 CDS yqhY NC_000964.3 2529926 2530333 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254; hypothetical protein complement(2529926..2530333) Bacillus subtilis subsp. subtilis str. 168 938598 NP_390314.2 CDS accC NC_000964.3 2530354 2531706 R an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1 complement(2530354..2531706) Bacillus subtilis subsp. subtilis str. 168 938588 NP_390315.1 CDS accB NC_000964.3 2531718 2532197 R composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxyl carrier protein of acetyl-CoA carboxylase complement(2531718..2532197) Bacillus subtilis subsp. subtilis str. 168 938587 NP_390316.2 CDS spoIIIAH NC_000964.3 2532353 2533009 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15752199, 16959571, 1766372; Product type cp: cell process; stage III sporulation protein AH complement(2532353..2533009) Bacillus subtilis subsp. subtilis str. 168 938600 NP_390317.2 CDS spoIIIAG NC_000964.3 2533010 2533699 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AG complement(2533010..2533699) Bacillus subtilis subsp. subtilis str. 168 938595 NP_390318.1 CDS spoIIIAF NC_000964.3 2533692 2534312 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AF complement(2533692..2534312) Bacillus subtilis subsp. subtilis str. 168 938576 NP_390319.2 CDS spoIIIAE NC_000964.3 2534326 2535525 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process; stage III sporulation protein AE complement(2534326..2535525) Bacillus subtilis subsp. subtilis str. 168 938569 NP_390320.1 CDS spoIIIAD NC_000964.3 2535544 2535945 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process; stage III sporulation protein AD complement(2535544..2535945) Bacillus subtilis subsp. subtilis str. 168 938577 NP_390321.1 CDS spoIIIAC NC_000964.3 2535952 2536158 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AC complement(2535952..2536158) Bacillus subtilis subsp. subtilis str. 168 938562 NP_390322.1 CDS spoIIIAB NC_000964.3 2536181 2536696 R necessary for complete engulfment of forespore; stage III sporulation protein AB complement(2536181..2536696) Bacillus subtilis subsp. subtilis str. 168 938561 NP_390323.1 CDS spoIIIAA NC_000964.3 2536690 2537613 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AA complement(2536690..2537613) Bacillus subtilis subsp. subtilis str. 168 938563 NP_390324.1 CDS yqhV NC_000964.3 2537689 2537970 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2537689..2537970) Bacillus subtilis subsp. subtilis str. 168 938559 NP_390325.2 CDS efp NC_000964.3 2538115 2538672 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(2538115..2538672) Bacillus subtilis subsp. subtilis str. 168 938558 NP_390326.1 CDS yqhT NC_000964.3 2538697 2539758 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YqhT complement(2538697..2539758) Bacillus subtilis subsp. subtilis str. 168 938560 NP_390327.1 CDS yqhS NC_000964.3 2539755 2540201 R catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase complement(2539755..2540201) Bacillus subtilis subsp. subtilis str. 168 938557 NP_390328.1 CDS yqhR NC_000964.3 2540288 2540824 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2540288..2540824) Bacillus subtilis subsp. subtilis str. 168 938555 NP_390329.2 CDS yqhQ NC_000964.3 2541051 2542007 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2541051..2542007 Bacillus subtilis subsp. subtilis str. 168 938556 NP_390330.1 CDS yqhP NC_000964.3 2542047 2542442 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2542047..2542442 Bacillus subtilis subsp. subtilis str. 168 938552 NP_390331.1 CDS yqhO NC_000964.3 2542439 2543314 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2542439..2543314) Bacillus subtilis subsp. subtilis str. 168 938553 NP_390332.2 CDS mntR NC_000964.3 2543440 2543868 R involved in manganese homeostasis; activates the transcription of the mntABCD operon; transcriptional regulator MntR complement(2543440..2543868) Bacillus subtilis subsp. subtilis str. 168 938554 NP_390333.1 CDS yqhM NC_000964.3 2543968 2544804 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; octanoyltransferase LipM complement(2543968..2544804) Bacillus subtilis subsp. subtilis str. 168 938551 NP_390334.2 CDS yqhL NC_000964.3 2544995 2545375 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11092948; Product type pe : enzyme; hypothetical protein 2544995..2545375 Bacillus subtilis subsp. subtilis str. 168 938550 NP_390335.1 CDS gcvPB NC_000964.3 2545410 2546876 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 complement(2545410..2546876) Bacillus subtilis subsp. subtilis str. 168 938549 NP_390336.2 CDS gcvPA NC_000964.3 2546869 2548215 R acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 complement(2546869..2548215) Bacillus subtilis subsp. subtilis str. 168 938546 NP_390337.2 CDS gcvT NC_000964.3 2548245 2549333 R catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; aminomethyltransferase complement(2548245..2549333) Bacillus subtilis subsp. subtilis str. 168 938547 NP_390338.1 CDS yqhH NC_000964.3 2549775 2551448 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YqhH 2549775..2551448 Bacillus subtilis subsp. subtilis str. 168 938548 NP_390339.1 CDS yqhG NC_000964.3 2551469 2552263 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2551469..2552263 Bacillus subtilis subsp. subtilis str. 168 938541 NP_390340.1 CDS sinI NC_000964.3 2552446 2552619 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10547280, 11751836, 15661000, 15805512, 8549812; Product type r: regulator; SinR antagonist SinI 2552446..2552619 Bacillus subtilis subsp. subtilis str. 168 938543 NP_390341.1 CDS sinR NC_000964.3 2552653 2552988 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15805512, 16585769, 16740951, 16923912; Product type r: regulator; XRE family transcriptional regulator 2552653..2552988 Bacillus subtilis subsp. subtilis str. 168 938544 NP_390342.1 CDS tasA NC_000964.3 2553081 2553866 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10827084, 16430695, 16430696, 18047568; Product type cp: cell process; spore coat protein N complement(2553081..2553866) Bacillus subtilis subsp. subtilis str. 168 938545 NP_390343.1 CDS sipW NC_000964.3 2553930 2554502 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 10827084, 15101989, 16430695; Product type e: enzyme; signal peptidase I W complement(2553930..2554502) Bacillus subtilis subsp. subtilis str. 168 938542 NP_390344.1 CDS yqxM NC_000964.3 2554486 2555247 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 14707086, 16430695, 17554552; Product type lp : lipoprotein; hypothetical protein complement(2554486..2555247) Bacillus subtilis subsp. subtilis str. 168 938532 NP_390345.1 CDS yqzG NC_000964.3 2555519 2555845 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 2555519..2555845 Bacillus subtilis subsp. subtilis str. 168 938529 NP_390346.2 CDS yqzE NC_000964.3 2555887 2556066 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2555887..2556066) Bacillus subtilis subsp. subtilis str. 168 938540 NP_390347.1 CDS comGG NC_000964.3 2556137 2556511 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 7 complement(2556137..2556511) Bacillus subtilis subsp. subtilis str. 168 938538 NP_390348.1 CDS comGF NC_000964.3 2556512 2556895 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 6 complement(2556512..2556895) Bacillus subtilis subsp. subtilis str. 168 938530 NP_390349.1 CDS comGE NC_000964.3 2556921 2557268 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 7783624, 9224890, 9422590, 9723928; Product type cp: cell process; ComG operon protein 5 complement(2556921..2557268) Bacillus subtilis subsp. subtilis str. 168 938518 NP_390350.1 CDS comGD NC_000964.3 2557252 2557683 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 9224890, 9422590, 9723928; Product type cp: cell process; ComG operon protein 4 complement(2557252..2557683) Bacillus subtilis subsp. subtilis str. 168 938531 NP_390351.1 CDS comGC NC_000964.3 2557673 2557969 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 16751195, 7783624, 9723928; Product type cp: cell process; ComG operon protein 3 complement(2557673..2557969) Bacillus subtilis subsp. subtilis str. 168 938526 NP_390352.1 CDS comGB NC_000964.3 2557983 2558954 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 2 complement(2557983..2558954) Bacillus subtilis subsp. subtilis str. 168 938527 NP_390353.1 CDS comGA NC_000964.3 2559007 2560077 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11298275, 15528548, 16009134, 9723928; Product type cp: cell process; ComG operon protein 1 complement(2559007..2560077) Bacillus subtilis subsp. subtilis str. 168 938516 NP_390354.1 CDS yqxL NC_000964.3 2560489 2561442 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15856219; Product type pt : transporter; magnesium transport protein CorA complement(2560489..2561442) Bacillus subtilis subsp. subtilis str. 168 938517 NP_390355.1 CDS yqhB NC_000964.3 2561585 2562913 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 2561585..2562913 Bacillus subtilis subsp. subtilis str. 168 938492 NP_390356.2 CDS rsbRD NC_000964.3 2562966 2563802 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT co-antagonist protein RsbRD complement(2562966..2563802) Bacillus subtilis subsp. subtilis str. 168 938513 NP_390357.2 CDS mgsR NC_000964.3 2564026 2564406 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18643936; Product type r: regulator; regulatory protein MgsR complement(2564026..2564406) Bacillus subtilis subsp. subtilis str. 168 938484 NP_390358.1 CDS yqgY NC_000964.3 2564638 2564883 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2564638..2564883 Bacillus subtilis subsp. subtilis str. 168 938215 NP_390359.1 CDS yqgX NC_000964.3 2564923 2565558 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2564923..2565558) Bacillus subtilis subsp. subtilis str. 168 938218 NP_390360.1 CDS yqgW NC_000964.3 2565715 2565888 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2565715..2565888 Bacillus subtilis subsp. subtilis str. 168 938217 NP_390361.2 CDS yqgV NC_000964.3 2565920 2566234 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2565920..2566234) Bacillus subtilis subsp. subtilis str. 168 938212 NP_390362.2 CDS yqgU NC_000964.3 2566237 2567298 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein complement(2566237..2567298) Bacillus subtilis subsp. subtilis str. 168 938213 NP_390363.1 CDS yqgT NC_000964.3 2567360 2568490 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12765833; Product type pe : enzyme; hypothetical protein complement(2567360..2568490) Bacillus subtilis subsp. subtilis str. 168 938214 NP_390364.2 CDS yqgS NC_000964.3 2568573 2570489 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; lipoteichoic acid synthase complement(2568573..2570489) Bacillus subtilis subsp. subtilis str. 168 938209 NP_390365.2 CDS glcK NC_000964.3 2570606 2571571 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15018644, 15050034, 9620975; Product type e: enzyme; glucokinase complement(2570606..2571571) Bacillus subtilis subsp. subtilis str. 168 938206 NP_390366.1 CDS yqgQ NC_000964.3 2571582 2571797 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15050034; hypothetical protein complement(2571582..2571797) Bacillus subtilis subsp. subtilis str. 168 938210 NP_390367.2 CDS glpG NC_000964.3 2571907 2573430 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15050034, 16355228; Product type e: enzyme; rhomboid protease GluP complement(2571907..2573430) Bacillus subtilis subsp. subtilis str. 168 938211 NP_390368.1 CDS yqgO NC_000964.3 2573520 2573693 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2573520..2573693) Bacillus subtilis subsp. subtilis str. 168 938204 NP_390369.1 CDS yqgN NC_000964.3 2573760 2574323 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17329806; Product type e: enzyme; hypothetical protein complement(2573760..2574323) Bacillus subtilis subsp. subtilis str. 168 938208 NP_570908.2 CDS rpmG NC_000964.3 2574408 2574557 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1 complement(2574408..2574557) Bacillus subtilis subsp. subtilis str. 168 937959 NP_390370.2 CDS yqgM NC_000964.3 2574641 2575720 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YqgM complement(2574641..2575720) Bacillus subtilis subsp. subtilis str. 168 938207 NP_390371.1 CDS yqgL NC_000964.3 2575717 2576187 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2575717..2576187) Bacillus subtilis subsp. subtilis str. 168 938201 NP_390372.1 CDS yqzD NC_000964.3 2576367 2576720 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2576367..2576720 Bacillus subtilis subsp. subtilis str. 168 938203 NP_390373.2 CDS yqzC NC_000964.3 2576717 2577181 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2576717..2577181 Bacillus subtilis subsp. subtilis str. 168 938202 NP_390374.1 CDS pstBB NC_000964.3 2577210 2577992 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate import ATP-binding protein PstB 1 complement(2577210..2577992) Bacillus subtilis subsp. subtilis str. 168 938205 NP_390375.1 CDS pstBA NC_000964.3 2578003 2578812 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate import ATP-binding protein PstB 2 complement(2578003..2578812) Bacillus subtilis subsp. subtilis str. 168 938198 NP_390376.2 CDS pstA NC_000964.3 2578833 2579717 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter; ABC transporter permease complement(2578833..2579717) Bacillus subtilis subsp. subtilis str. 168 938200 NP_390377.2 CDS pstC NC_000964.3 2579717 2580646 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter; ABC transporter permease complement(2579717..2580646) Bacillus subtilis subsp. subtilis str. 168 938184 NP_390378.1 CDS pstS NC_000964.3 2580715 2581617 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 15289558, 9098050, 9593301; Product type t: transporter; phosphate-binding protein PstS complement(2580715..2581617) Bacillus subtilis subsp. subtilis str. 168 938197 NP_390379.1 CDS pbpA NC_000964.3 2581771 2583921 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990, 9139922, 9851991; Product type e: enzyme; hypothetical protein complement(2581771..2583921) Bacillus subtilis subsp. subtilis str. 168 938199 NP_390380.2 CDS yqgE NC_000964.3 2584035 2585327 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(2584035..2585327) Bacillus subtilis subsp. subtilis str. 168 938196 NP_390381.3 CDS sodA NC_000964.3 2585434 2586042 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074093, 15897454, 18084079, 9393707, 9573176, 9658017; Product type e : enzyme; superoxide dismutase complement(2585434..2586042) Bacillus subtilis subsp. subtilis str. 168 938052 NP_390382.1 CDS yqgC NC_000964.3 2586221 2586703 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2586221..2586703) Bacillus subtilis subsp. subtilis str. 168 938138 NP_390383.2 CDS yqgB NC_000964.3 2586813 2587580 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype; hypothetical protein 2586813..2587580 Bacillus subtilis subsp. subtilis str. 168 937983 NP_390384.2 CDS yqgA NC_000964.3 2587996 2588424 R Evidence 5: No homology to any previously reported sequences; cell wall-binding protein YqgA complement(2587996..2588424) Bacillus subtilis subsp. subtilis str. 168 937963 NP_390385.1 CDS yqfZ NC_000964.3 2588701 2589000 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype; hypothetical protein 2588701..2589000 Bacillus subtilis subsp. subtilis str. 168 938027 NP_390386.1 CDS ispG NC_000964.3 2589123 2590256 D catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2589123..2590256 Bacillus subtilis subsp. subtilis str. 168 937984 NP_390387.1 CDS yqfX NC_000964.3 2590282 2590671 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2590282..2590671) Bacillus subtilis subsp. subtilis str. 168 937973 NP_390388.1 CDS yqfW NC_000964.3 2590804 2591385 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; nucleotidase YqfW 2590804..2591385 Bacillus subtilis subsp. subtilis str. 168 937915 NP_390389.2 CDS zur NC_000964.3 2591428 2591865 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12180919, 12426338, 12904577, 17216355; Product type r: regulator; zinc-specific metallo-regulatory protein complement(2591428..2591865) Bacillus subtilis subsp. subtilis str. 168 937968 NP_390390.2 CDS yqfU NC_000964.3 2592003 2592884 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2592003..2592884) Bacillus subtilis subsp. subtilis str. 168 937944 NP_390391.1 CDS yqfT NC_000964.3 2593000 2593254 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2593000..2593254 Bacillus subtilis subsp. subtilis str. 168 937909 NP_390392.1 CDS yqfS NC_000964.3 2593281 2594174 R Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV complement(2593281..2594174) Bacillus subtilis subsp. subtilis str. 168 937922 NP_390393.1 CDS cshB NC_000964.3 2594184 2595500 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871, 16352840, 18203828; Product type e: enzyme; DEAD/DEAH box helicase complement(2594184..2595500) Bacillus subtilis subsp. subtilis str. 168 937908 NP_390394.1 CDS yqfQ NC_000964.3 2595669 2596412 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2595669..2596412 Bacillus subtilis subsp. subtilis str. 168 937910 NP_390395.2 CDS ispH NC_000964.3 2596535 2597479 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2596535..2597479 Bacillus subtilis subsp. subtilis str. 168 937900 NP_390396.1 CDS yqfO NC_000964.3 2597502 2598623 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2597502..2598623) Bacillus subtilis subsp. subtilis str. 168 937901 NP_390397.1 CDS trmK NC_000964.3 2598616 2599266 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18420655; Product type e: enzyme; tRNA: m1A22 methyltransferase complement(2598616..2599266) Bacillus subtilis subsp. subtilis str. 168 937898 NP_390398.1 CDS cccA NC_000964.3 2599523 2599885 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10024472, 10473570, 11361075, 15995641; Product type c: carrier; cytochrome c-550 complement(2599523..2599885) Bacillus subtilis subsp. subtilis str. 168 937902 NP_390399.2 CDS sigA NC_000964.3 2600214 2601329 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD complement(2600214..2601329) Bacillus subtilis subsp. subtilis str. 168 937897 NP_390400.2 CDS dnaG NC_000964.3 2601528 2603339 R synthesizes RNA primers at the replication forks; DNA primase complement(2601528..2603339) Bacillus subtilis subsp. subtilis str. 168 937899 YP_054587.1 CDS antE NC_000964.3 2602979 2603275 D Evidence 5: No homology to any previously reported sequences; PubMedId: 9864351; protein AntE 2602979..2603275 Bacillus subtilis subsp. subtilis str. 168 2914189 NP_390401.2 CDS yqxD NC_000964.3 2603373 2603867 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9387153; hypothetical protein complement(2603373..2603867) Bacillus subtilis subsp. subtilis str. 168 937896 NP_390402.1 CDS yqfL NC_000964.3 2604121 2604933 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator; hypothetical protein complement(2604121..2604933) Bacillus subtilis subsp. subtilis str. 168 937889 NP_390403.1 CDS ccpN NC_000964.3 2604959 2605597 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator; transcriptional repressor CcpN complement(2604959..2605597) Bacillus subtilis subsp. subtilis str. 168 937886 NP_390404.2 CDS glyS NC_000964.3 2605730 2607769 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycine--tRNA ligase beta subunit complement(2605730..2607769) Bacillus subtilis subsp. subtilis str. 168 937887 NP_390405.1 CDS glyQ NC_000964.3 2607762 2608649 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycine--tRNA ligase alpha subunit complement(2607762..2608649) Bacillus subtilis subsp. subtilis str. 168 937888 NP_390406.2 CDS recO NC_000964.3 2608946 2609713 R involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO complement(2608946..2609713) Bacillus subtilis subsp. subtilis str. 168 937881 YP_003097761.1 CDS yqzL NC_000964.3 2609750 2609893 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2609750..2609893) Bacillus subtilis subsp. subtilis str. 168 8303204 NP_390407.1 CDS era NC_000964.3 2610041 2610946 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTPase Era complement(2610041..2610946) Bacillus subtilis subsp. subtilis str. 168 937871 NP_390408.1 CDS cdd NC_000964.3 2610927 2611337 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217788, 2526291, 8157589; Product type e: enzyme; cytidine deaminase complement(2610927..2611337) Bacillus subtilis subsp. subtilis str. 168 937885 NP_390409.2 CDS dgkA NC_000964.3 2611456 2611827 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923107, 17535816; Product type e: enzyme; undecaprenol kinase complement(2611456..2611827) Bacillus subtilis subsp. subtilis str. 168 937873 NP_390410.2 CDS yqfG NC_000964.3 2611808 2612281 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metalloprotease complement(2611808..2612281) Bacillus subtilis subsp. subtilis str. 168 937869 NP_390411.1 CDS yqfF NC_000964.3 2612282 2614417 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751502; Product type pe : enzyme; hypothetical protein complement(2612282..2614417) Bacillus subtilis subsp. subtilis str. 168 937877 NP_390412.2 CDS phoH NC_000964.3 2614496 2615455 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12762842; Product type ph: phenotype; PhoH-like protein complement(2614496..2615455) Bacillus subtilis subsp. subtilis str. 168 937868 NP_390413.2 CDS yqfD NC_000964.3 2615452 2616648 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14523133; Product type cp: cell process; hypothetical protein complement(2615452..2616648) Bacillus subtilis subsp. subtilis str. 168 937867 NP_390414.1 CDS yqfC NC_000964.3 2616667 2616948 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922; hypothetical protein complement(2616667..2616948) Bacillus subtilis subsp. subtilis str. 168 937870 NP_390415.2 CDS yqfB NC_000964.3 2617005 2617424 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2617005..2617424) Bacillus subtilis subsp. subtilis str. 168 937864 NP_390416.1 CDS yqfA NC_000964.3 2617449 2618444 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12501411; Product type cp : cell process; hypothetical protein complement(2617449..2618444) Bacillus subtilis subsp. subtilis str. 168 937865 NP_390417.1 CDS yqeZ NC_000964.3 2618466 2619779 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2618466..2619779) Bacillus subtilis subsp. subtilis str. 168 937859 NP_390418.1 CDS yqeY NC_000964.3 2619910 2620356 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2619910..2620356) Bacillus subtilis subsp. subtilis str. 168 937860 NP_390419.1 CDS rpsU NC_000964.3 2620371 2620544 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(2620371..2620544) Bacillus subtilis subsp. subtilis str. 168 937861 NP_390420.2 CDS yqeW NC_000964.3 2620717 2621640 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 2620717..2621640 Bacillus subtilis subsp. subtilis str. 168 937858 NP_390421.1 CDS rimO NC_000964.3 2621677 2623032 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572129, 15339930, 18252828, 8844851; Product type e: enzyme; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB complement(2621677..2623032) Bacillus subtilis subsp. subtilis str. 168 937857 NP_390422.1 CDS yqeU NC_000964.3 2623032 2623802 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; ribosomal RNA small subunit methyltransferase E complement(2623032..2623802) Bacillus subtilis subsp. subtilis str. 168 937856 NP_390423.2 CDS prmA NC_000964.3 2623825 2624760 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase complement(2623825..2624760) Bacillus subtilis subsp. subtilis str. 168 937847 NP_390424.2 CDS dnaJ NC_000964.3 2624785 2625912 R chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ complement(2624785..2625912) Bacillus subtilis subsp. subtilis str. 168 937848 NP_390425.1 CDS dnaK NC_000964.3 2626112 2627947 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; chaperone protein DnaK complement(2626112..2627947) Bacillus subtilis subsp. subtilis str. 168 937849 NP_390426.1 CDS grpE NC_000964.3 2627971 2628534 R with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE complement(2627971..2628534) Bacillus subtilis subsp. subtilis str. 168 937846 NP_390427.1 CDS hrcA NC_000964.3 2628606 2629637 R Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor HrcA complement(2628606..2629637) Bacillus subtilis subsp. subtilis str. 168 937843 NP_390428.2 CDS hemN NC_000964.3 2629718 2630857 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; oxygen-independent coproporphyrinogen-III oxidase 1 complement(2629718..2630857) Bacillus subtilis subsp. subtilis str. 168 937845 NP_390429.1 CDS lepA NC_000964.3 2630910 2632748 R binds to the ribosome on the universally-conserved alpha-sarcin loop; elongation factor 4 complement(2630910..2632748) Bacillus subtilis subsp. subtilis str. 168 937840 NP_390430.1 CDS yqxA NC_000964.3 2632882 2633220 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2632882..2633220) Bacillus subtilis subsp. subtilis str. 168 937841 NP_390431.1 CDS spoIIP NC_000964.3 2633237 2634442 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17376078; Product type cp: cell process; stage II sporulation protein P complement(2633237..2634442) Bacillus subtilis subsp. subtilis str. 168 937842 NP_390432.1 CDS gpr NC_000964.3 2634505 2635611 R Initiates the rapid degradation of small acid-soluble proteins during spore germination; germination protease complement(2634505..2635611) Bacillus subtilis subsp. subtilis str. 168 937838 NP_390433.2 CDS rpsT NC_000964.3 2635815 2636081 D binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2635815..2636081 Bacillus subtilis subsp. subtilis str. 168 937837 NP_390434.1 CDS holA NC_000964.3 2636096 2637139 R required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; hypothetical protein complement(2636096..2637139) Bacillus subtilis subsp. subtilis str. 168 937833 YP_003097762.1 CDS yqzM NC_000964.3 2637369 2637503 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2637369..2637503 Bacillus subtilis subsp. subtilis str. 168 8303117 NP_390435.1 CDS comEC NC_000964.3 2637543 2639873 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12123453, 15661011, 16751195; Product type cp: cell process; ComE operon protein 3 complement(2637543..2639873) Bacillus subtilis subsp. subtilis str. 168 937839 NP_390436.1 CDS comEB NC_000964.3 2639877 2640446 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7768800; Product type cp : cell process; ComE operon protein 2 complement(2639877..2640446) Bacillus subtilis subsp. subtilis str. 168 937832 NP_390437.1 CDS comEA NC_000964.3 2640513 2641130 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195; Product type cp: cell process; ComE operon protein 1 complement(2640513..2641130) Bacillus subtilis subsp. subtilis str. 168 937827 NP_390438.1 CDS comER NC_000964.3 2641214 2642035 D may be involved in regulation of competence genes; ComE operon protein 4 2641214..2642035 Bacillus subtilis subsp. subtilis str. 168 937834 NP_390439.1 CDS yqeM NC_000964.3 2642101 2642844 R Evidence 4: Homologs of previously reported genes of unknown function; methyltransferase complement(2642101..2642844) Bacillus subtilis subsp. subtilis str. 168 937826 NP_390440.1 CDS yqeL NC_000964.3 2642841 2643197 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2642841..2643197) Bacillus subtilis subsp. subtilis str. 168 937819 NP_390441.1 CDS yqeK NC_000964.3 2643215 2643775 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311; Product type pe : enzyme; hypothetical protein complement(2643215..2643775) Bacillus subtilis subsp. subtilis str. 168 937831 NP_390442.1 CDS nadD NC_000964.3 2643765 2644334 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinate-nucleotide adenylyltransferase complement(2643765..2644334) Bacillus subtilis subsp. subtilis str. 168 937818 NP_390443.1 CDS yqeI NC_000964.3 2644346 2644636 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 17005971, 17105995; Product type pf: factor; RNA-binding protein YqeI complement(2644346..2644636) Bacillus subtilis subsp. subtilis str. 168 937813 NP_390444.2 CDS aroE NC_000964.3 2644630 2645472 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate dehydrogenase complement(2644630..2645472) Bacillus subtilis subsp. subtilis str. 168 937820 NP_390445.1 CDS yqeH NC_000964.3 2645490 2646590 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; hypothetical protein complement(2645490..2646590) Bacillus subtilis subsp. subtilis str. 168 937822 NP_390446.1 CDS yqeG NC_000964.3 2646594 2647112 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2646594..2647112) Bacillus subtilis subsp. subtilis str. 168 937815 YP_054588.1 CDS sda NC_000964.3 2647456 2647614 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15023339, 16796683, 19040634; Product type f: factor; sporulation inhibitor sda 2647456..2647614 Bacillus subtilis subsp. subtilis str. 168 2914223 NP_390447.1 CDS yqeF NC_000964.3 2647920 2648651 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoprotein complement(2647920..2648651) Bacillus subtilis subsp. subtilis str. 168 937814 NP_390448.1 CDS cwlH NC_000964.3 2648903 2649655 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10974124, 15687192; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase CwlH complement(2648903..2649655) Bacillus subtilis subsp. subtilis str. 168 937808 NP_390449.1 CDS yqeD NC_000964.3 2649842 2650468 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 15855514, 16850406; hypothetical protein 2649842..2650468 Bacillus subtilis subsp. subtilis str. 168 937812 NP_390450.1 CDS yqeC NC_000964.3 2650487 2651380 R similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase YqeC complement(2650487..2651380) Bacillus subtilis subsp. subtilis str. 168 937809 NP_390451.2 CDS yqeB NC_000964.3 2651632 2652354 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2651632..2652354 Bacillus subtilis subsp. subtilis str. 168 937802 NP_390452.1 CDS nucB NC_000964.3 2652387 2652797 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17209033, 7746143; Product type e: enzyme; sporulation-specific extracellular nuclease complement(2652387..2652797) Bacillus subtilis subsp. subtilis str. 168 937804 NP_390454.2 CDS spoIVCA NC_000964.3 2653371 2654873 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1631085, 2163341, 7704261, 8300549, 8969508; Product type e: enzyme; DNA recombinase complement(2653371..2654873) Bacillus subtilis subsp. subtilis str. 168 937799 NP_390455.1 CDS arsC NC_000964.3 2655322 2655741 R catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates; arsenate reductase ArsC complement(2655322..2655741) Bacillus subtilis subsp. subtilis str. 168 937801 NP_390456.2 CDS arsB NC_000964.3 2655753 2656793 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 16905151, 9537360; Product type t: transporter; arsenite resistance protein ArsB complement(2655753..2656793) Bacillus subtilis subsp. subtilis str. 168 937800 NP_390457.2 CDS yqcK NC_000964.3 2656816 2657256 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16905151, 8760915, 8969508, 9537360; Product type pe: enzyme; hypothetical protein complement(2656816..2657256) Bacillus subtilis subsp. subtilis str. 168 937794 NP_390458.1 CDS arsR NC_000964.3 2657317 2657634 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537360; Product type r : regulator; arsenical resistance operon repressor complement(2657317..2657634) Bacillus subtilis subsp. subtilis str. 168 937789 NP_390459.2 CDS yqcI NC_000964.3 2658006 2658770 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8760915, 8969508; Product type h : extrachromosomal origin; hypothetical protein complement(2658006..2658770) Bacillus subtilis subsp. subtilis str. 168 937795 NP_390460.2 CDS rapE NC_000964.3 2659213 2660340 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10629174, 11679073, 12897006, 8760915, 8969508; Product type r: regulator; response regulator aspartate phosphatase E 2659213..2660340 Bacillus subtilis subsp. subtilis str. 168 937796 NP_390461.1 CDS phrE NC_000964.3 2660330 2660464 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174; Product type r: regulator; phosphatase RapE inhibitor 2660330..2660464 Bacillus subtilis subsp. subtilis str. 168 937784 NP_390462.1 CDS yqzI NC_000964.3 2660574 2660732 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2660574..2660732 Bacillus subtilis subsp. subtilis str. 168 937791 NP_390463.1 CDS yqcG NC_000964.3 2661102 2662697 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2661102..2662697 Bacillus subtilis subsp. subtilis str. 168 937792 NP_390464.1 CDS yqcF NC_000964.3 2662712 2663290 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2662712..2663290 Bacillus subtilis subsp. subtilis str. 168 937785 NP_390465.1 CDS yqxJ NC_000964.3 2663551 2663913 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2663551..2663913) Bacillus subtilis subsp. subtilis str. 168 937786 NP_390466.1 CDS yqxI NC_000964.3 2663929 2664408 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2663929..2664408) Bacillus subtilis subsp. subtilis str. 168 937775 NP_390467.1 CDS cwlA NC_000964.3 2664573 2665391 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1683402, 2127796; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase CwlA complement(2664573..2665391) Bacillus subtilis subsp. subtilis str. 168 937772 NP_390468.1 CDS yqxH NC_000964.3 2665436 2665858 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2665436..2665858) Bacillus subtilis subsp. subtilis str. 168 937782 NP_390469.1 CDS yqxG NC_000964.3 2665903 2666796 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2665903..2666796) Bacillus subtilis subsp. subtilis str. 168 937783 NP_390470.1 CDS yqcE NC_000964.3 2666884 2667048 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2666884..2667048) Bacillus subtilis subsp. subtilis str. 168 937759 NP_390471.1 CDS yqcD NC_000964.3 2667045 2667380 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2667045..2667380) Bacillus subtilis subsp. subtilis str. 168 937768 NP_390472.2 CDS yqcC NC_000964.3 2667390 2668490 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein complement(2667390..2668490) Bacillus subtilis subsp. subtilis str. 168 937773 NP_390473.1 CDS yqcB NC_000964.3 2668493 2668765 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2668493..2668765) Bacillus subtilis subsp. subtilis str. 168 937762 NP_390474.2 CDS yqcA NC_000964.3 2668762 2669340 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein complement(2668762..2669340) Bacillus subtilis subsp. subtilis str. 168 937763 NP_390475.1 CDS yqbT NC_000964.3 2669324 2670370 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2669324..2670370) Bacillus subtilis subsp. subtilis str. 168 937758 NP_390476.1 CDS yqbS NC_000964.3 2670363 2670788 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2670363..2670788) Bacillus subtilis subsp. subtilis str. 168 937757 NP_390477.1 CDS yqbR NC_000964.3 2670801 2671064 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2670801..2671064) Bacillus subtilis subsp. subtilis str. 168 937750 NP_390478.1 CDS yqbQ NC_000964.3 2671061 2672041 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2671061..2672041) Bacillus subtilis subsp. subtilis str. 168 937751 NP_390479.1 CDS yqbP NC_000964.3 2672054 2672713 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2672054..2672713) Bacillus subtilis subsp. subtilis str. 168 937756 NP_390480.2 CDS yqbO NC_000964.3 2672706 2677463 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8760915, 8969508; Product type pe: enzyme; hypothetical protein complement(2672706..2677463) Bacillus subtilis subsp. subtilis str. 168 937747 NP_390482.1 CDS yqdB NC_000964.3 2678240 2678419 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2678240..2678419 Bacillus subtilis subsp. subtilis str. 168 8303122 NP_390483.2 CDS yqbM NC_000964.3 2679142 2679585 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein complement(2679142..2679585) Bacillus subtilis subsp. subtilis str. 168 937740 NP_390485.2 CDS yqbK NC_000964.3 2679588 2680988 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2679588..2680988) Bacillus subtilis subsp. subtilis str. 168 937738 YP_003097763.1 CDS yqzN NC_000964.3 2680989 2681180 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2680989..2681180) Bacillus subtilis subsp. subtilis str. 168 8303132 NP_390486.2 CDS yqbJ NC_000964.3 2681177 2681614 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2681177..2681614) Bacillus subtilis subsp. subtilis str. 168 937746 NP_390487.1 CDS yqbI NC_000964.3 2681627 2682130 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2681627..2682130) Bacillus subtilis subsp. subtilis str. 168 937737 NP_390488.1 CDS yqbH NC_000964.3 2682127 2682489 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2682127..2682489) Bacillus subtilis subsp. subtilis str. 168 937727 NP_390489.2 CDS yqbG NC_000964.3 2682486 2682881 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2682486..2682881) Bacillus subtilis subsp. subtilis str. 168 937739 NP_390490.1 CDS yqbF NC_000964.3 2682885 2683196 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2682885..2683196) Bacillus subtilis subsp. subtilis str. 168 937735 NP_390491.2 CDS yqbE NC_000964.3 2683207 2684142 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2683207..2684142) Bacillus subtilis subsp. subtilis str. 168 937722 NP_390492.2 CDS yqbD NC_000964.3 2684161 2685129 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2684161..2685129) Bacillus subtilis subsp. subtilis str. 168 937736 NP_390493.1 CDS yqbC NC_000964.3 2685162 2685815 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2685162..2685815) Bacillus subtilis subsp. subtilis str. 168 937712 NP_390494.1 CDS yqbB NC_000964.3 2685856 2686773 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2685856..2686773) Bacillus subtilis subsp. subtilis str. 168 937723 NP_390495.1 CDS yqbA NC_000964.3 2686770 2688302 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2686770..2688302) Bacillus subtilis subsp. subtilis str. 168 937707 NP_390496.1 CDS yqaT NC_000964.3 2688306 2689601 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2688306..2689601) Bacillus subtilis subsp. subtilis str. 168 937721 NP_390497.1 CDS yqaS NC_000964.3 2689594 2690313 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2689594..2690313) Bacillus subtilis subsp. subtilis str. 168 937704 NP_390498.1 CDS yqaR NC_000964.3 2690381 2690845 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2690381..2690845) Bacillus subtilis subsp. subtilis str. 168 937703 NP_390499.1 CDS yqaQ NC_000964.3 2690989 2691444 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2690989..2691444) Bacillus subtilis subsp. subtilis str. 168 937693 NP_390500.1 CDS yqaP NC_000964.3 2691642 2692571 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2691642..2692571 Bacillus subtilis subsp. subtilis str. 168 937705 NP_390501.1 CDS yqaO NC_000964.3 2692645 2692851 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2692645..2692851) Bacillus subtilis subsp. subtilis str. 168 937706 NP_390502.1 CDS yqaN NC_000964.3 2692933 2693361 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2692933..2693361) Bacillus subtilis subsp. subtilis str. 168 937694 YP_003097764.1 CDS yqzO NC_000964.3 2693457 2693606 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2693457..2693606) Bacillus subtilis subsp. subtilis str. 168 8302984 NP_390503.2 CDS yqaM NC_000964.3 2693597 2694457 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2693597..2694457) Bacillus subtilis subsp. subtilis str. 168 937685 NP_390504.2 CDS yqaL NC_000964.3 2694420 2695097 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein complement(2694420..2695097) Bacillus subtilis subsp. subtilis str. 168 937695 NP_390505.1 CDS yqaK NC_000964.3 2695173 2696027 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2695173..2696027) Bacillus subtilis subsp. subtilis str. 168 937691 NP_390506.1 CDS yqaJ NC_000964.3 2696030 2696989 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2696030..2696989) Bacillus subtilis subsp. subtilis str. 168 937681 NP_390507.1 CDS yqaI NC_000964.3 2697095 2697289 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2697095..2697289) Bacillus subtilis subsp. subtilis str. 168 937680 NP_390508.1 CDS yqaH NC_000964.3 2697419 2697676 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2697419..2697676) Bacillus subtilis subsp. subtilis str. 168 937692 NP_390509.1 CDS yqaG NC_000964.3 2697673 2698242 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator complement(2697673..2698242) Bacillus subtilis subsp. subtilis str. 168 937671 NP_390510.1 CDS yqdA NC_000964.3 2698316 2698456 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2698316..2698456) Bacillus subtilis subsp. subtilis str. 168 937682 NP_390511.1 CDS yqaF NC_000964.3 2698486 2698716 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator complement(2698486..2698716) Bacillus subtilis subsp. subtilis str. 168 937684 NP_390512.1 CDS yqaE NC_000964.3 2698893 2699243 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2698893..2699243 Bacillus subtilis subsp. subtilis str. 168 937672 NP_390513.1 CDS yqaD NC_000964.3 2699510 2699677 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2699510..2699677) Bacillus subtilis subsp. subtilis str. 168 937674 NP_390514.1 CDS yqaC NC_000964.3 2700033 2700569 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2700033..2700569) Bacillus subtilis subsp. subtilis str. 168 937669 NP_390515.1 CDS yqaB NC_000964.3 2700838 2701356 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2700838..2701356 Bacillus subtilis subsp. subtilis str. 168 937668 NP_390517.1 CDS yrkS NC_000964.3 2701979 2702143 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2701979..2702143) Bacillus subtilis subsp. subtilis str. 168 937670 NP_390518.2 CDS yrkR NC_000964.3 2702688 2703104 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12897016, 15849754, 16850406; Product type m : membrane component; phosphate-starvation-inducible protein PsiE complement(2702688..2703104) Bacillus subtilis subsp. subtilis str. 168 937665 NP_390519.1 CDS yrkQ NC_000964.3 2703150 2704448 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase complement(2703150..2704448) Bacillus subtilis subsp. subtilis str. 168 937662 NP_390520.1 CDS yrkP NC_000964.3 2704435 2705130 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 18175906; Product type r: regulator; transcriptional regulator complement(2704435..2705130) Bacillus subtilis subsp. subtilis str. 168 937663 NP_390521.1 CDS yrkO NC_000964.3 2705398 2706615 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2705398..2706615 Bacillus subtilis subsp. subtilis str. 168 937667 NP_390522.1 CDS yrkN NC_000964.3 2707127 2707684 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2707127..2707684 Bacillus subtilis subsp. subtilis str. 168 937664 NP_390524.2 CDS yrkL NC_000964.3 2708175 2708699 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053405; Product type pe : enzyme; NAD(P)H oxidoreductase YrkL complement(2708175..2708699) Bacillus subtilis subsp. subtilis str. 168 937658 NP_390525.2 CDS yrkK NC_000964.3 2708943 2709419 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2708943..2709419) Bacillus subtilis subsp. subtilis str. 168 937659 NP_390526.1 CDS yrkJ NC_000964.3 2710002 2710787 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2710002..2710787) Bacillus subtilis subsp. subtilis str. 168 937654 NP_390527.1 CDS yrkI NC_000964.3 2710848 2711075 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2710848..2711075) Bacillus subtilis subsp. subtilis str. 168 937657 NP_390528.2 CDS yrkH NC_000964.3 2711109 2712242 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2711109..2712242) Bacillus subtilis subsp. subtilis str. 168 937656 NP_390530.1 CDS yrkF NC_000964.3 2712577 2713134 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2712577..2713134) Bacillus subtilis subsp. subtilis str. 168 937647 NP_390531.1 CDS yrkE NC_000964.3 2713320 2713802 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2713320..2713802) Bacillus subtilis subsp. subtilis str. 168 937651 NP_390532.1 CDS yrkD NC_000964.3 2713949 2714140 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2713949..2714140) Bacillus subtilis subsp. subtilis str. 168 937650 NP_390533.1 CDS yrkC NC_000964.3 2714933 2715493 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme; hypothetical protein complement(2714933..2715493) Bacillus subtilis subsp. subtilis str. 168 937645 NP_390534.1 CDS yrkB NC_000964.3 2715719 2715865 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2715719..2715865) Bacillus subtilis subsp. subtilis str. 168 937648 NP_390535.1 CDS bltR NC_000964.3 2716035 2716856 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 7608059, 9083003; Product type r: regulator; multidrug-efflux transporter 2 regulator complement(2716035..2716856) Bacillus subtilis subsp. subtilis str. 168 937644 NP_390536.1 CDS blt NC_000964.3 2716973 2718175 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 15849754, 16850406, 9083003; Product type t : transporter; multidrug resistance protein 2 2716973..2718175 Bacillus subtilis subsp. subtilis str. 168 937646 NP_390537.1 CDS bltD NC_000964.3 2718344 2718802 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 9083003; Product type e: enzyme; spermine/spermidine acetyltransferase 2718344..2718802 Bacillus subtilis subsp. subtilis str. 168 937632 NP_390538.1 CDS yrkA NC_000964.3 2718959 2720263 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(2718959..2720263) Bacillus subtilis subsp. subtilis str. 168 937634 YP_003097765.1 CDS yrzO NC_000964.3 2720526 2720669 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2720526..2720669) Bacillus subtilis subsp. subtilis str. 168 8303041 NP_390539.1 CDS yrdR NC_000964.3 2720687 2721652 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(2720687..2721652) Bacillus subtilis subsp. subtilis str. 168 937629 NP_390540.1 CDS yrdQ NC_000964.3 2721778 2722644 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator 2721778..2722644 Bacillus subtilis subsp. subtilis str. 168 937628 NP_390541.1 CDS yrdP NC_000964.3 2722767 2723804 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12100555, 12527699, 9099864; Product type pe: enzyme; oxidoreductase complement(2722767..2723804) Bacillus subtilis subsp. subtilis str. 168 937340 NP_390542.1 CDS czcD NC_000964.3 2723892 2724827 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 12100555, 15849754, 15948947, 16850406; Product type t : transporter; cadmium, cobalt and zinc/H complement(2723892..2724827) Bacillus subtilis subsp. subtilis str. 168 937630 NP_390543.1 CDS yrdN NC_000964.3 2725114 2725503 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YrdN complement(2725114..2725503) Bacillus subtilis subsp. subtilis str. 168 937627 NP_390544.2 CDS gltR NC_000964.3 2725837 2726727 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9023181; Product type r : regulator; LysR family transcriptional regulator 2725837..2726727 Bacillus subtilis subsp. subtilis str. 168 938189 NP_390545.2 CDS yrdK NC_000964.3 2726885 2727163 R Evidence 6: Doubtful CDS; hypothetical protein complement(2726885..2727163) Bacillus subtilis subsp. subtilis str. 168 938740 NP_390546.1 CDS brnQ NC_000964.3 2727160 2728482 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8544834, 9287000, 9531631; Product type t: transporter; branched-chain amino acid transport system carrier protein BrnQ complement(2727160..2728482) Bacillus subtilis subsp. subtilis str. 168 936930 NP_390547.1 CDS azlD NC_000964.3 2728647 2728979 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type pt: transporter; branched-chain amino acid transport protein AzlD complement(2728647..2728979) Bacillus subtilis subsp. subtilis str. 168 937624 NP_390548.1 CDS azlC NC_000964.3 2728976 2729740 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 9287000; Product type t: transporter; branched-chain amino acid transport protein AzlC complement(2728976..2729740) Bacillus subtilis subsp. subtilis str. 168 936606 NP_390549.1 CDS azlB NC_000964.3 2729753 2730226 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type r : regulator; transcriptional regulator AzlB complement(2729753..2730226) Bacillus subtilis subsp. subtilis str. 168 937625 NP_390550.1 CDS yrdF NC_000964.3 2730560 2730835 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; ribonuclease inhibitor YrdF complement(2730560..2730835) Bacillus subtilis subsp. subtilis str. 168 936691 NP_390551.1 CDS cypA NC_000964.3 2731107 2732339 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 9778370; Product type e: enzyme; cytochrome P450 complement(2731107..2732339) Bacillus subtilis subsp. subtilis str. 168 937623 NP_390553.1 CDS yrdC NC_000964.3 2732980 2733543 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase complement(2732980..2733543) Bacillus subtilis subsp. subtilis str. 168 937618 NP_390554.1 CDS yrdB NC_000964.3 2733772 2734143 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2733772..2734143) Bacillus subtilis subsp. subtilis str. 168 936140 NP_390555.1 CDS yrdA NC_000964.3 2734953 2735456 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2734953..2735456) Bacillus subtilis subsp. subtilis str. 168 937620 NP_390556.1 CDS aadK NC_000964.3 2735682 2736536 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8293959; Product type e : enzyme; aminoglycoside 6-adenylyltransferase complement(2735682..2736536) Bacillus subtilis subsp. subtilis str. 168 938061 NP_390557.1 CDS yrpB NC_000964.3 2736915 2737958 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9501443; Product type pe : enzyme; nitronate monooxygenase 2736915..2737958 Bacillus subtilis subsp. subtilis str. 168 936455 NP_390558.1 CDS yrpC NC_000964.3 2738308 2739105 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15347750; Product type e: enzyme; glutamate racemase 2738308..2739105 Bacillus subtilis subsp. subtilis str. 168 937619 NP_390559.1 CDS yrpD NC_000964.3 2739486 2740193 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 2739486..2740193 Bacillus subtilis subsp. subtilis str. 168 937397 NP_390560.1 CDS yrpE NC_000964.3 2741357 2742112 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; zinc-binding protein complement(2741357..2742112) Bacillus subtilis subsp. subtilis str. 168 936254 NP_390561.1 CDS sigZ NC_000964.3 2742244 2742774 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigZ complement(2742244..2742774) Bacillus subtilis subsp. subtilis str. 168 937617 NP_390562.2 CDS yrpG NC_000964.3 2742909 2743889 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2742909..2743889 Bacillus subtilis subsp. subtilis str. 168 937611 NP_390563.1 CDS yraO NC_000964.3 2744163 2745479 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053381, 15849754, 16850406; Product type pt: transporter; transporter complement(2744163..2745479) Bacillus subtilis subsp. subtilis str. 168 937610 NP_390564.1 CDS yraN NC_000964.3 2745594 2746463 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator complement(2745594..2746463) Bacillus subtilis subsp. subtilis str. 168 937614 NP_390565.2 CDS yraM NC_000964.3 2746608 2747711 D Evidence 4: Homologs of previously reported genes of unknown function; isomerase 2746608..2747711 Bacillus subtilis subsp. subtilis str. 168 936343 NP_390566.1 CDS csn NC_000964.3 2747984 2748817 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065371, 11320136, 1664582; Product type e: enzyme; chitosanase complement(2747984..2748817) Bacillus subtilis subsp. subtilis str. 168 936802 NP_390567.1 CDS yraL NC_000964.3 2749260 2749523 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2749260..2749523 Bacillus subtilis subsp. subtilis str. 168 937608 NP_390568.2 CDS yraK NC_000964.3 2749660 2750475 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YraK 2749660..2750475 Bacillus subtilis subsp. subtilis str. 168 936746 NP_390569.2 CDS yraJ NC_000964.3 2750883 2751239 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2750883..2751239) Bacillus subtilis subsp. subtilis str. 168 937609 NP_390570.1 CDS yraI NC_000964.3 2751292 2751726 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2751292..2751726) Bacillus subtilis subsp. subtilis str. 168 936030 NP_390571.1 CDS yraH NC_000964.3 2752167 2752553 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(2752167..2752553) Bacillus subtilis subsp. subtilis str. 168 937607 NP_390572.1 CDS yraG NC_000964.3 2752802 2753047 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2752802..2753047 Bacillus subtilis subsp. subtilis str. 168 936783 NP_390573.1 CDS yraF NC_000964.3 2753065 2753433 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2753065..2753433 Bacillus subtilis subsp. subtilis str. 168 937606 NP_390574.2 CDS adhB NC_000964.3 2753452 2754588 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7926692; Product type pe : enzyme; zinc-type alcohol dehydrogenase 2753452..2754588 Bacillus subtilis subsp. subtilis str. 168 937604 NP_390575.1 CDS yraE NC_000964.3 2754607 2754804 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2754607..2754804 Bacillus subtilis subsp. subtilis str. 168 938108 NP_390576.1 CDS yraD NC_000964.3 2754820 2755119 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2754820..2755119 Bacillus subtilis subsp. subtilis str. 168 935919 NP_390578.2 CDS yraB NC_000964.3 2755382 2755804 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator; MerR family transcriptional regulator complement(2755382..2755804) Bacillus subtilis subsp. subtilis str. 168 937605 NP_390579.2 CDS adhA NC_000964.3 2756312 2757361 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; formaldehyde dehydrogenase AdhA 2756312..2757361 Bacillus subtilis subsp. subtilis str. 168 938739 NP_390580.2 CDS yraA NC_000964.3 2757492 2758001 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12775685, 17257049, 17933887; Product type f: factor; cysteine protease YraA 2757492..2758001 Bacillus subtilis subsp. subtilis str. 168 937603 NP_390581.1 CDS sacC NC_000964.3 2758043 2760076 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7646030, 8057358; Product type e: enzyme; levanase complement(2758043..2760076) Bacillus subtilis subsp. subtilis str. 168 938092 NP_390582.1 CDS levG NC_000964.3 2760233 2761060 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IID complement(2760233..2761060) Bacillus subtilis subsp. subtilis str. 168 937595 NP_390583.1 CDS levF NC_000964.3 2761081 2761890 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IIC complement(2761081..2761890) Bacillus subtilis subsp. subtilis str. 168 937602 NP_390584.1 CDS levE NC_000964.3 2761907 2762395 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589728, 9033408, 9622354; Product type t: transporter; PTS system fructose-specific transporter subunit IIB complement(2761907..2762395) Bacillus subtilis subsp. subtilis str. 168 937078 NP_390585.1 CDS levD NC_000964.3 2762395 2762835 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IIA complement(2762395..2762835) Bacillus subtilis subsp. subtilis str. 168 936536 NP_390586.2 CDS levR NC_000964.3 2763025 2765832 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1619665, 1900939, 7592487, 8057358, 9622354; Product type r: regulator; transcriptional regulatory protein LevR complement(2763025..2765832) Bacillus subtilis subsp. subtilis str. 168 937594 NP_390587.2 CDS aapA NC_000964.3 2766558 2767946 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter; amino acid permease AapA 2766558..2767946 Bacillus subtilis subsp. subtilis str. 168 937231 NP_390588.1 CDS yrhP NC_000964.3 2768042 2768674 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein complement(2768042..2768674) Bacillus subtilis subsp. subtilis str. 168 937592 NP_390589.1 CDS yrhO NC_000964.3 2768827 2769654 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2768827..2769654 Bacillus subtilis subsp. subtilis str. 168 937224 NP_390590.1 CDS sigV NC_000964.3 2769850 2770350 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator; RNA polymerase sigma factor SigV 2769850..2770350 Bacillus subtilis subsp. subtilis str. 168 937591 NP_390591.1 CDS rsiV NC_000964.3 2770350 2771207 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator; anti-sigma-V factor RsiV 2770350..2771207 Bacillus subtilis subsp. subtilis str. 168 937593 NP_390592.1 CDS oatA NC_000964.3 2771318 2773222 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15661003; Product type e: enzyme; peptidoglycan O-acetyltransferase YrhL 2771318..2773222 Bacillus subtilis subsp. subtilis str. 168 936583 NP_390593.1 CDS yrhK NC_000964.3 2773356 2773646 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2773356..2773646 Bacillus subtilis subsp. subtilis str. 168 937587 NP_390594.1 CDS cypB NC_000964.3 2773890 2777054 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type e: enzyme; bifunctional P-450/NADPH-P450 reductase 2 complement(2773890..2777054) Bacillus subtilis subsp. subtilis str. 168 937585 NP_390595.1 CDS bscR NC_000964.3 2777070 2777654 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type r: regulator; TetR family transcriptional regulator complement(2777070..2777654) Bacillus subtilis subsp. subtilis str. 168 938491 NP_390596.1 CDS yrhH NC_000964.3 2777877 2778419 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pe : enzyme; methyltransferase complement(2777877..2778419) Bacillus subtilis subsp. subtilis str. 168 938507 NP_390597.1 CDS yrzI NC_000964.3 2778923 2779072 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2778923..2779072) Bacillus subtilis subsp. subtilis str. 168 937584 NP_390598.1 CDS yrhG NC_000964.3 2779462 2780262 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(2779462..2780262) Bacillus subtilis subsp. subtilis str. 168 937992 NP_390599.1 CDS yrhF NC_000964.3 2780525 2780893 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2780525..2780893) Bacillus subtilis subsp. subtilis str. 168 936371 NP_390600.1 CDS yrhE NC_000964.3 2781209 2784151 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913079; Product type pe : enzyme; formate dehydrogenase YrhE 2781209..2784151 Bacillus subtilis subsp. subtilis str. 168 937569 NP_390601.1 CDS yrhD NC_000964.3 2784170 2784652 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; hypothetical protein 2784170..2784652 Bacillus subtilis subsp. subtilis str. 168 937583 NP_390602.1 CDS yrhC NC_000964.3 2784688 2784918 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751; hypothetical protein complement(2784688..2784918) Bacillus subtilis subsp. subtilis str. 168 936495 NP_390603.1 CDS yrhB NC_000964.3 2785001 2786140 R catalyzes the formation of L-homocysteine from cystathionine; cystathionine gamma-lyase complement(2785001..2786140) Bacillus subtilis subsp. subtilis str. 168 936947 NP_390604.1 CDS mccA NC_000964.3 2786142 2787065 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751; Product type e: enzyme; O-acetylserine dependent cystathionine beta-synthase complement(2786142..2787065) Bacillus subtilis subsp. subtilis str. 168 937576 NP_390605.1 CDS mtn NC_000964.3 2787130 2787825 R enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase complement(2787130..2787825) Bacillus subtilis subsp. subtilis str. 168 938153 NP_390606.1 CDS yrrT NC_000964.3 2787846 2788487 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 17056751; Product type pe: enzyme; methyltransferase complement(2787846..2788487) Bacillus subtilis subsp. subtilis str. 168 937566 NP_390607.1 CDS yrzA NC_000964.3 2788680 2788883 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2788680..2788883 Bacillus subtilis subsp. subtilis str. 168 937564 NP_390608.1 CDS yrrS NC_000964.3 2788920 2789621 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14679248; membrane protein complement(2788920..2789621) Bacillus subtilis subsp. subtilis str. 168 936614 NP_390609.1 CDS pbpI NC_000964.3 2789686 2791440 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679248; Product type e: enzyme; penicillin-binding protein 4B complement(2789686..2791440) Bacillus subtilis subsp. subtilis str. 168 936016 NP_390610.1 CDS greA NC_000964.3 2791494 2791967 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(2791494..2791967) Bacillus subtilis subsp. subtilis str. 168 937565 NP_390611.1 CDS udk NC_000964.3 2792218 2792853 R functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase complement(2792218..2792853) Bacillus subtilis subsp. subtilis str. 168 937560 NP_390612.1 CDS yrrO NC_000964.3 2792860 2794128 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YrrO complement(2792860..2794128) Bacillus subtilis subsp. subtilis str. 168 937561 NP_390613.1 CDS yrrN NC_000964.3 2794147 2795076 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YrrN complement(2794147..2795076) Bacillus subtilis subsp. subtilis str. 168 937559 NP_390614.1 CDS yrrM NC_000964.3 2795082 2795735 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; O-methyltransferase YrrM complement(2795082..2795735) Bacillus subtilis subsp. subtilis str. 168 937719 NP_390615.1 CDS yrrL NC_000964.3 2795887 2796969 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2795887..2796969) Bacillus subtilis subsp. subtilis str. 168 936260 NP_390616.1 CDS yrzB NC_000964.3 2797100 2797381 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein complement(2797100..2797381) Bacillus subtilis subsp. subtilis str. 168 938000 NP_390617.1 CDS yrrK NC_000964.3 2797399 2797815 R similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase complement(2797399..2797815) Bacillus subtilis subsp. subtilis str. 168 937357 YP_054589.1 CDS yrzL NC_000964.3 2797823 2798089 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2797823..2798089) Bacillus subtilis subsp. subtilis str. 168 2914283 NP_390618.1 CDS alaS NC_000964.3 2798174 2800810 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanine--tRNA ligase complement(2798174..2800810) Bacillus subtilis subsp. subtilis str. 168 939643 NP_390619.1 CDS yrrI NC_000964.3 2801141 2802202 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(2801141..2802202) Bacillus subtilis subsp. subtilis str. 168 937557 NP_390620.1 CDS glnQ NC_000964.3 2802358 2803086 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type t: transporter; glutamine transport ATP-binding protein GlnQ 2802358..2803086 Bacillus subtilis subsp. subtilis str. 168 937558 NP_390621.1 CDS glnH NC_000964.3 2803108 2803929 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type lp: lipoprotein; ABC transporter glutamine-binding protein GlnH 2803108..2803929 Bacillus subtilis subsp. subtilis str. 168 938139 NP_390622.1 CDS glnM NC_000964.3 2803990 2804640 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter; glutamine ABC transporter permease protein GlnM 2803990..2804640 Bacillus subtilis subsp. subtilis str. 168 935975 NP_390623.1 CDS glnP NC_000964.3 2804657 2805313 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter; glutamine ABC transporter permease protein GlnP 2804657..2805313 Bacillus subtilis subsp. subtilis str. 168 937556 YP_003097766.1 CDS yrzQ NC_000964.3 2805348 2805479 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2805348..2805479) Bacillus subtilis subsp. subtilis str. 168 8302994 YP_003097767.1 CDS yrzR NC_000964.3 2805501 2805692 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2805501..2805692) Bacillus subtilis subsp. subtilis str. 168 8302944 NP_390624.1 CDS yrrD NC_000964.3 2805704 2806228 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2805704..2806228) Bacillus subtilis subsp. subtilis str. 168 937552 NP_390625.1 CDS yrrC NC_000964.3 2806286 2808682 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557815, 3537961; Product type pe: enzyme; hypothetical protein complement(2806286..2808682) Bacillus subtilis subsp. subtilis str. 168 937553 NP_390626.1 CDS yrrB NC_000964.3 2808707 2809327 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11777911, 12594026; Product type pf: factor; TPR repeat-containing protein YrrB complement(2808707..2809327) Bacillus subtilis subsp. subtilis str. 168 938093 NP_390627.3 CDS mnmA NC_000964.3 2809413 2810528 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(2809413..2810528) Bacillus subtilis subsp. subtilis str. 168 938049 NP_390629.2 CDS iscS NC_000964.3 2810559 2811698 R Evidence 2b: Function of strongly homologous gene; PubMedId: 10930739, 12682299, 17064282, 7496536; Product type e: enzyme; cysteine desulfurase IscS 1 complement(2810559..2811698) Bacillus subtilis subsp. subtilis str. 168 937550 NP_390630.2 CDS cymR NC_000964.3 2811717 2812133 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668000, 16109943, 16513748, 17056751, 18974048; Product type r: regulator; Rrf2 family transcriptional regulator complement(2811717..2812133) Bacillus subtilis subsp. subtilis str. 168 936456 NP_390631.1 CDS yrvN NC_000964.3 2812336 2813601 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATPase 2812336..2813601 Bacillus subtilis subsp. subtilis str. 168 937545 NP_390632.3 CDS yrvM NC_000964.3 2813643 2814407 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177353; Product type pe : enzyme; hypothetical protein complement(2813643..2814407) Bacillus subtilis subsp. subtilis str. 168 938590 NP_390633.1 CDS aspS NC_000964.3 2814743 2816521 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartate--tRNA ligase complement(2814743..2816521) Bacillus subtilis subsp. subtilis str. 168 937549 NP_390634.1 CDS hisS NC_000964.3 2816535 2817809 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidine--tRNA ligase complement(2816535..2817809) Bacillus subtilis subsp. subtilis str. 168 938617 NP_390635.1 CDS yrzK NC_000964.3 2818191 2818361 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2818191..2818361) Bacillus subtilis subsp. subtilis str. 168 936478 NP_390636.1 CDS yrvJ NC_000964.3 2818494 2820050 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetylmuramoyl-L-alanine amidase YrvJ 2818494..2820050 Bacillus subtilis subsp. subtilis str. 168 937544 NP_390637.2 CDS yrvI NC_000964.3 2820077 2820475 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(2820077..2820475) Bacillus subtilis subsp. subtilis str. 168 936530 NP_390638.2 CDS relA NC_000964.3 2820529 2822733 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11545276, 12081964, 13129942, 15066282, 6248722; Product type e: enzyme; GTP pyrophosphokinase complement(2820529..2822733) Bacillus subtilis subsp. subtilis str. 168 936753 NP_390639.1 CDS apt NC_000964.3 2822901 2823413 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(2822901..2823413) Bacillus subtilis subsp. subtilis str. 168 938063 NP_390640.1 CDS recJ NC_000964.3 2823419 2825779 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; single-stranded-dna-specific exonuclease RecJ complement(2823419..2825779) Bacillus subtilis subsp. subtilis str. 168 937538 NP_390641.1 CDS yrvD NC_000964.3 2825846 2826169 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2825846..2826169) Bacillus subtilis subsp. subtilis str. 168 937537 NP_390642.1 CDS yrvC NC_000964.3 2826245 2826742 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter; hypothetical protein complement(2826245..2826742) Bacillus subtilis subsp. subtilis str. 168 937539 NP_390643.1 CDS secDF NC_000964.3 2826900 2829113 R part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; protein translocase subunit SecDF complement(2826900..2829113) Bacillus subtilis subsp. subtilis str. 168 937938 NP_390644.1 CDS comN NC_000964.3 2829152 2829448 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 19028902; Product type r: regulator; post-transcriptional regulator complement(2829152..2829448) Bacillus subtilis subsp. subtilis str. 168 937536 NP_390645.1 CDS spoVB NC_000964.3 2829564 2831120 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15292147, 15849754, 16850406, 1744050; Product type pt: transporter; stage V sporulation protein B 2829564..2831120 Bacillus subtilis subsp. subtilis str. 168 938022 NP_390646.1 CDS yrbG NC_000964.3 2831124 2831780 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2831124..2831780) Bacillus subtilis subsp. subtilis str. 168 937535 NP_390647.1 CDS yrzE NC_000964.3 2831915 2832367 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2831915..2832367 Bacillus subtilis subsp. subtilis str. 168 938165 NP_390648.2 CDS yajC NC_000964.3 2832424 2832690 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(2832424..2832690) Bacillus subtilis subsp. subtilis str. 168 936257 NP_390649.1 CDS tgt NC_000964.3 2832727 2833872 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(2832727..2833872) Bacillus subtilis subsp. subtilis str. 168 937528 NP_390650.1 CDS queA NC_000964.3 2833899 2834927 R Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase complement(2833899..2834927) Bacillus subtilis subsp. subtilis str. 168 937975 YP_003097768.1 CDS yrzS NC_000964.3 2834957 2835157 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(2834957..2835157) Bacillus subtilis subsp. subtilis str. 168 8303137 YP_054590.1 CDS ruvB NC_000964.3 2835150 2836154 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; holliday junction ATP-dependent DNA helicase RuvB complement(2835150..2836154) Bacillus subtilis subsp. subtilis str. 168 2914219 NP_390652.1 CDS ruvA NC_000964.3 2836165 2836770 R plays an essential role in ATP-dependent branch migration of the Holliday junction; holliday junction ATP-dependent DNA helicase RuvA complement(2836165..2836770) Bacillus subtilis subsp. subtilis str. 168 937829 NP_390653.1 CDS bofC NC_000964.3 2836909 2837421 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931291, 16049010; Product type f: factor; general stress protein BofC complement(2836909..2837421) Bacillus subtilis subsp. subtilis str. 168 937526 NP_390654.2 CDS csbX NC_000964.3 2837469 2838776 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9099855; Product type pt: transporter; alpha-ketoglutarate permease complement(2837469..2838776) Bacillus subtilis subsp. subtilis str. 168 937527 NP_390655.1 CDS yrbE NC_000964.3 2838847 2839872 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(2838847..2839872) Bacillus subtilis subsp. subtilis str. 168 936523 NP_390656.2 CDS yrzF NC_000964.3 2840110 2840757 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase 2840110..2840757 Bacillus subtilis subsp. subtilis str. 168 936570 NP_390658.1 CDS yrzH NC_000964.3 2841169 2841300 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2841169..2841300 Bacillus subtilis subsp. subtilis str. 168 936007 YP_003097769.1 CDS yrzT NC_000964.3 2841307 2841447 D Evidence 5: No homology to any previously reported sequences; membrane protein 2841307..2841447 Bacillus subtilis subsp. subtilis str. 168 8303183 NP_390659.2 CDS yrbD NC_000964.3 2841611 2843065 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1400476, 15849754, 16850406; Product type t : transporter; sodium/proton-dependent alanine carrier protein YrbD 2841611..2843065 Bacillus subtilis subsp. subtilis str. 168 937941 NP_390660.1 CDS yrbC NC_000964.3 2843106 2843828 R Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator complement(2843106..2843828) Bacillus subtilis subsp. subtilis str. 168 937517 NP_390661.2 CDS coxA NC_000964.3 2843931 2844527 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9770294; Product type f: factor; sporulation cortex protein CoxA complement(2843931..2844527) Bacillus subtilis subsp. subtilis str. 168 937516 NP_390662.1 CDS safA NC_000964.3 2844675 2845838 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438771, 10714986, 11040425, 15901704; Product type f: factor; spoivd-associated factor A complement(2844675..2845838) Bacillus subtilis subsp. subtilis str. 168 937514 NP_390663.1 CDS nadA NC_000964.3 2845955 2847061 R 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthase A complement(2845955..2847061) Bacillus subtilis subsp. subtilis str. 168 937522 NP_390664.1 CDS nadC NC_000964.3 2847048 2847917 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(2847048..2847917) Bacillus subtilis subsp. subtilis str. 168 936245 NP_390665.1 CDS nadB NC_000964.3 2847871 2849466 R catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase complement(2847871..2849466) Bacillus subtilis subsp. subtilis str. 168 938051 NP_390666.1 CDS nifS NC_000964.3 2849569 2850756 D catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase NifS 2849569..2850756 Bacillus subtilis subsp. subtilis str. 168 936637 NP_390667.2 CDS nadR NC_000964.3 2850716 2851258 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16199587, 18276644; Product type r: regulator; transcription repressor NadR 2850716..2851258 Bacillus subtilis subsp. subtilis str. 168 937515 NP_390668.1 CDS pheA NC_000964.3 2851283 2852140 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(2851283..2852140) Bacillus subtilis subsp. subtilis str. 168 937513 NP_390669.1 CDS pheB NC_000964.3 2852157 2852600 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 2537815; hypothetical protein complement(2852157..2852600) Bacillus subtilis subsp. subtilis str. 168 938171 NP_390670.1 CDS obgE NC_000964.3 2852661 2853947 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(2852661..2853947) Bacillus subtilis subsp. subtilis str. 168 937502 NP_390671.1 CDS spo0B NC_000964.3 2853981 2854559 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10997904, 9443976, 9477965, 9726997, 9809070; Product type e: enzyme; sporulation initiation phosphotransferase B complement(2853981..2854559) Bacillus subtilis subsp. subtilis str. 168 935956 NP_390672.1 CDS rpmA NC_000964.3 2854880 2855164 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(2854880..2855164) Bacillus subtilis subsp. subtilis str. 168 937511 NP_390673.2 CDS ysxB NC_000964.3 2855177 2855515 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11567142; hypothetical protein complement(2855177..2855515) Bacillus subtilis subsp. subtilis str. 168 937961 NP_390674.1 CDS rplU NC_000964.3 2855518 2855826 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299; Product type f: factor; 50S ribosomal protein L21 complement(2855518..2855826) Bacillus subtilis subsp. subtilis str. 168 936368 NP_390675.1 CDS spoIVFB NC_000964.3 2855973 2856839 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type cp : cell process; stage IV sporulation protein FB complement(2855973..2856839) Bacillus subtilis subsp. subtilis str. 168 937505 NP_390676.1 CDS spoIVFA NC_000964.3 2856832 2857626 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type r : regulator; stage IV sporulation protein FA complement(2856832..2857626) Bacillus subtilis subsp. subtilis str. 168 937501 NP_390677.1 CDS minD NC_000964.3 2857776 2858582 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11886553, 12426398, 12492852, 12492861, 16322744, 16885474, 17513368; Product type cp: cell process; septum site-determining protein MinD complement(2857776..2858582) Bacillus subtilis subsp. subtilis str. 168 937499 NP_390678.1 CDS minC NC_000964.3 2858584 2859264 R blocks the formation of polar Z-ring septums; septum site-determining protein MinC complement(2858584..2859264) Bacillus subtilis subsp. subtilis str. 168 937500 NP_390679.1 CDS mreD NC_000964.3 2859317 2859835 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16101995, 16850406; Product type s: structure; rod shape-determining protein MreD complement(2859317..2859835) Bacillus subtilis subsp. subtilis str. 168 936183 NP_390680.2 CDS mreC NC_000964.3 2859832 2860704 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; cell shape-determining protein MreC complement(2859832..2860704) Bacillus subtilis subsp. subtilis str. 168 937498 NP_390681.2 CDS mreB NC_000964.3 2860735 2861748 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(2860735..2861748) Bacillus subtilis subsp. subtilis str. 168 936759 NP_390682.1 CDS radC NC_000964.3 2861840 2862535 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; hypothetical protein complement(2861840..2862535) Bacillus subtilis subsp. subtilis str. 168 936544 NP_390683.1 CDS maf NC_000964.3 2862572 2863141 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; septum formation protein Maf complement(2862572..2863141) Bacillus subtilis subsp. subtilis str. 168 936605 NP_390684.1 CDS spoIIB NC_000964.3 2863294 2864292 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16959571, 17376078; Product type cp: cell process; stage II sporulation protein B complement(2863294..2864292) Bacillus subtilis subsp. subtilis str. 168 937497 NP_390685.2 CDS comC NC_000964.3 2864426 2865172 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16751195, 16850406, 2553669, 9723928; Product type cp: cell process; type 4 prepilin-like proteins leader peptide-processing enzyme complement(2864426..2865172) Bacillus subtilis subsp. subtilis str. 168 936586 NP_390686.1 CDS folC NC_000964.3 2865312 2866604 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2105929, 2985605, 3040739, 6994831, 9098041; Product type e: enzyme; folylpolyglutamate synthase complement(2865312..2866604) Bacillus subtilis subsp. subtilis str. 168 936327 NP_390687.2 CDS valS NC_000964.3 2866664 2869306 R valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valine--tRNA ligase complement(2866664..2869306) Bacillus subtilis subsp. subtilis str. 168 937491 YP_003097770.1 CDS yszA NC_000964.3 2869754 2869945 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2869754..2869945 Bacillus subtilis subsp. subtilis str. 168 8302989 NP_390688.1 CDS ysxE NC_000964.3 2869964 2870989 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16371471, 16390444; Product type cp: cell process; hypothetical protein complement(2869964..2870989) Bacillus subtilis subsp. subtilis str. 168 937496 NP_390689.1 CDS spoVID NC_000964.3 2871022 2872749 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11325931, 16371471, 16950916; Product type cp: cell process; stage VI sporulation protein D complement(2871022..2872749) Bacillus subtilis subsp. subtilis str. 168 936772 NP_390690.1 CDS hemL NC_000964.3 2872880 2874172 R Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde 2,1-aminomutase complement(2872880..2874172) Bacillus subtilis subsp. subtilis str. 168 937490 NP_390691.1 CDS hemB NC_000964.3 2874202 2875176 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(2874202..2875176) Bacillus subtilis subsp. subtilis str. 168 936972 NP_390692.1 CDS hemD NC_000964.3 2875173 2875961 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 15802251, 2110138; Product type e: enzyme; uroporphyrinogen-iii synthase complement(2875173..2875961) Bacillus subtilis subsp. subtilis str. 168 937287 NP_390693.1 CDS hemC NC_000964.3 2875951 2876895 R transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase complement(2875951..2876895) Bacillus subtilis subsp. subtilis str. 168 937488 NP_390694.2 CDS hemX NC_000964.3 2876928 2877758 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12029044, 15802251, 15849754, 16850406, 8012594; Product type f: factor; protein HemX complement(2876928..2877758) Bacillus subtilis subsp. subtilis str. 168 937489 NP_390695.1 CDS hemA NC_000964.3 2877766 2879133 R catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase complement(2877766..2879133) Bacillus subtilis subsp. subtilis str. 168 937443 NP_390696.2 CDS ysxD NC_000964.3 2879363 2879860 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2879363..2879860 Bacillus subtilis subsp. subtilis str. 168 937352 NP_390697.1 CDS engB NC_000964.3 2879882 2880469 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; GTP-binding protein EngB complement(2879882..2880469) Bacillus subtilis subsp. subtilis str. 168 938009 NP_390698.1 CDS lonA NC_000964.3 2880466 2882790 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926, 15987505; Product type e: enzyme; Lon protease 1 complement(2880466..2882790) Bacillus subtilis subsp. subtilis str. 168 937486 NP_390699.1 CDS lonB NC_000964.3 2882971 2884629 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926; Product type e: enzyme; Lon protease 2 complement(2882971..2884629) Bacillus subtilis subsp. subtilis str. 168 937484 NP_390700.2 CDS clpX NC_000964.3 2884781 2886043 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent Clp protease ATP-binding subunit ClpX complement(2884781..2886043) Bacillus subtilis subsp. subtilis str. 168 937482 NP_390701.1 CDS tig NC_000964.3 2886315 2887589 R Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor complement(2886315..2887589) Bacillus subtilis subsp. subtilis str. 168 936610 NP_390702.2 CDS ysoA NC_000964.3 2887817 2888821 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; TPR repeat-containing protein YsoA complement(2887817..2888821) Bacillus subtilis subsp. subtilis str. 168 937479 NP_390703.1 CDS leuD NC_000964.3 2888940 2889539 R catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; 3-isopropylmalate dehydratase small subunit complement(2888940..2889539) Bacillus subtilis subsp. subtilis str. 168 937683 NP_390704.1 CDS leuC NC_000964.3 2889552 2890970 R dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; 3-isopropylmalate dehydratase large subunit complement(2889552..2890970) Bacillus subtilis subsp. subtilis str. 168 937478 NP_390705.2 CDS leuB NC_000964.3 2891020 2892117 R catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase complement(2891020..2892117) Bacillus subtilis subsp. subtilis str. 168 936221 NP_390706.1 CDS leuA NC_000964.3 2892138 2893694 R catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase complement(2892138..2893694) Bacillus subtilis subsp. subtilis str. 168 936316 NP_390707.1 CDS ilvC NC_000964.3 2893681 2894709 R catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase complement(2893681..2894709) Bacillus subtilis subsp. subtilis str. 168 937475 NP_390708.2 CDS ilvH NC_000964.3 2894733 2895251 R with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase small subunit complement(2894733..2895251) Bacillus subtilis subsp. subtilis str. 168 937477 NP_390709.1 CDS ilvB NC_000964.3 2895248 2896972 R catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase large subunit complement(2895248..2896972) Bacillus subtilis subsp. subtilis str. 168 936792 NP_390710.1 CDS ysnD NC_000964.3 2897788 2898123 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 2897788..2898123 Bacillus subtilis subsp. subtilis str. 168 937466 NP_390711.1 CDS ysnE NC_000964.3 2898292 2898747 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YsnE 2898292..2898747 Bacillus subtilis subsp. subtilis str. 168 937464 NP_390712.3 CDS ysnF NC_000964.3 2898931 2899752 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type ph : phenotype; stress response protein YsnF 2898931..2899752 Bacillus subtilis subsp. subtilis str. 168 936228 NP_390713.2 CDS ysnB NC_000964.3 2900020 2900529 R Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; metallophosphoesterase complement(2900020..2900529) Bacillus subtilis subsp. subtilis str. 168 938021 NP_390714.1 CDS ysnA NC_000964.3 2900545 2901141 R hydrolyzes non-standard nucleotides such as xanthine and inosine; non-canonical purine NTP pyrophosphatase complement(2900545..2901141) Bacillus subtilis subsp. subtilis str. 168 937465 NP_390715.1 CDS rph NC_000964.3 2901154 2901891 R RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH complement(2901154..2901891) Bacillus subtilis subsp. subtilis str. 168 937463 NP_390716.1 CDS gerM NC_000964.3 2902002 2903102 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14662349; Product type cp: cell process; spore germination protein GerM complement(2902002..2903102) Bacillus subtilis subsp. subtilis str. 168 936490 NP_390717.2 CDS racE NC_000964.3 2903217 2904035 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(2903217..2904035) Bacillus subtilis subsp. subtilis str. 168 935934 NP_390718.1 CDS ysmB NC_000964.3 2904043 2904483 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator complement(2904043..2904483) Bacillus subtilis subsp. subtilis str. 168 937461 NP_390719.2 CDS gerE NC_000964.3 2904727 2904951 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11243786, 11418558, 11741866, 14702409, 17172339; Product type cp: cell process; spore germination protein GerE complement(2904727..2904951) Bacillus subtilis subsp. subtilis str. 168 937462 NP_390720.1 CDS ysmA NC_000964.3 2905067 2905510 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2905067..2905510) Bacillus subtilis subsp. subtilis str. 168 937652 NP_390721.1 CDS sdhB NC_000964.3 2905571 2906332 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit complement(2905571..2906332) Bacillus subtilis subsp. subtilis str. 168 937460 NP_390722.2 CDS sdhA NC_000964.3 2906335 2908095 R part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit complement(2906335..2908095) Bacillus subtilis subsp. subtilis str. 168 937600 NP_390723.1 CDS sdhC NC_000964.3 2908129 2908737 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11803018, 15849754, 16850406, 1707123; Product type e: enzyme; succinate dehydrogenase cytochrome b558 subunit complement(2908129..2908737) Bacillus subtilis subsp. subtilis str. 168 937458 NP_390724.1 CDS yslB NC_000964.3 2909030 2909476 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2909030..2909476 Bacillus subtilis subsp. subtilis str. 168 936806 NP_390725.1 CDS lysC NC_000964.3 2909520 2910746 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartokinase 2 complement(2909520..2910746) Bacillus subtilis subsp. subtilis str. 168 937451 NP_390727.2 CDS uvrC NC_000964.3 2911116 2912888 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; UvrABC system protein C complement(2911116..2912888) Bacillus subtilis subsp. subtilis str. 168 937729 NP_390728.1 CDS trxA NC_000964.3 2913024 2913338 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15937154; Product type c: carrier; thioredoxin complement(2913024..2913338) Bacillus subtilis subsp. subtilis str. 168 938187 NP_390729.2 CDS xsa NC_000964.3 2913661 2915148 R Evidence 2b: Function of strongly homologous gene; PubMedId: 14973026; Product type e: enzyme; alpha-L-arabinofuranosidase complement(2913661..2915148) Bacillus subtilis subsp. subtilis str. 168 937449 NP_390730.1 CDS etfA NC_000964.3 2915365 2916342 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; electron transfer flavoprotein subunit alpha complement(2915365..2916342) Bacillus subtilis subsp. subtilis str. 168 936520 NP_390731.1 CDS etfB NC_000964.3 2916378 2917151 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10026281, 17189250; Product type e: enzyme; electron transfer flavoprotein subunit beta complement(2916378..2917151) Bacillus subtilis subsp. subtilis str. 168 937962 NP_390732.1 CDS ysiB NC_000964.3 2917166 2917942 R Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase complement(2917166..2917942) Bacillus subtilis subsp. subtilis str. 168 937448 NP_390733.1 CDS fadR NC_000964.3 2917957 2918541 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type r: regulator; fatty acid metabolism regulator protein complement(2917957..2918541) Bacillus subtilis subsp. subtilis str. 168 938105 NP_390734.1 CDS lcfA NC_000964.3 2918646 2920328 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; long-chain-fatty-acid--CoA ligase complement(2918646..2920328) Bacillus subtilis subsp. subtilis str. 168 936505 NP_390735.1 CDS yshE NC_000964.3 2920517 2920921 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2920517..2920921) Bacillus subtilis subsp. subtilis str. 168 937969 NP_390736.1 CDS mutSB NC_000964.3 2920936 2923293 R MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; methyl-directed mismatch repair protein MutS complement(2920936..2923293) Bacillus subtilis subsp. subtilis str. 168 937447 NP_390737.1 CDS yshC NC_000964.3 2923314 2925026 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18938175; Product type e: enzyme; DNA polymerase/3'-5' exonuclease PolX complement(2923314..2925026) Bacillus subtilis subsp. subtilis str. 168 937426 NP_390738.1 CDS yshB NC_000964.3 2925100 2925633 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; transmembrane protein YshB complement(2925100..2925633) Bacillus subtilis subsp. subtilis str. 168 937446 NP_390739.1 CDS yshA NC_000964.3 2925640 2925897 R Evidence 4: Homologs of previously reported genes of unknown function; cell division protein ZapA complement(2925640..2925897) Bacillus subtilis subsp. subtilis str. 168 937442 NP_390740.1 CDS rnhC NC_000964.3 2926031 2926972 D An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 2926031..2926972 Bacillus subtilis subsp. subtilis str. 168 937436 NP_390741.1 CDS pheT NC_000964.3 2927008 2929422 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanine--tRNA ligase beta subunit complement(2927008..2929422) Bacillus subtilis subsp. subtilis str. 168 937445 NP_390742.1 CDS pheS NC_000964.3 2929438 2930472 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanine--tRNA ligase alpha subunit complement(2929438..2930472) Bacillus subtilis subsp. subtilis str. 168 937987 NP_390743.1 CDS ysgA NC_000964.3 2930827 2931573 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tRNA/rRNA methyltransferase YsgA complement(2930827..2931573) Bacillus subtilis subsp. subtilis str. 168 937444 NP_390744.1 CDS sspI NC_000964.3 2931692 2931907 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362, 8171126; Product type f: factor; small acid-soluble spore protein I 2931692..2931907 Bacillus subtilis subsp. subtilis str. 168 937579 NP_390745.2 CDS ysfB NC_000964.3 2931976 2933082 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2931976..2933082 Bacillus subtilis subsp. subtilis str. 168 937437 NP_390746.1 CDS glcD NC_000964.3 2933185 2934597 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8606183; Product type e: enzyme; glycolate oxidase subunit GlcD 2933185..2934597 Bacillus subtilis subsp. subtilis str. 168 937770 NP_390747.1 CDS glcF NC_000964.3 2934594 2935928 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; glycolate oxidase iron-sulfur subunit 2934594..2935928 Bacillus subtilis subsp. subtilis str. 168 937435 NP_390748.1 CDS ysfE NC_000964.3 2935967 2936209 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(2935967..2936209) Bacillus subtilis subsp. subtilis str. 168 937588 NP_390749.2 CDS cstA NC_000964.3 2936382 2938178 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1848300; Product type ph : phenotype; carbon starvation protein A homolog complement(2936382..2938178) Bacillus subtilis subsp. subtilis str. 168 937970 NP_390750.2 CDS abfA NC_000964.3 2938330 2939832 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 12777810, 14973026, 16233670; Product type e: enzyme; alpha-L-arabinofuranosidase complement(2938330..2939832) Bacillus subtilis subsp. subtilis str. 168 937509 NP_390751.2 CDS araQ NC_000964.3 2939851 2940696 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter; L-arabinose transport system permease protein AraQ complement(2939851..2940696) Bacillus subtilis subsp. subtilis str. 168 937434 NP_390752.1 CDS araP NC_000964.3 2940697 2941638 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter; L-arabinose transport system permease protein AraP complement(2940697..2941638) Bacillus subtilis subsp. subtilis str. 168 937432 NP_390753.2 CDS araN NC_000964.3 2941674 2942975 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026; Product type lp : lipoprotein; arabinose-binding protein complement(2941674..2942975) Bacillus subtilis subsp. subtilis str. 168 937433 NP_390754.1 CDS araM NC_000964.3 2943006 2944190 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme; glycerol-1-phosphate dehydrogenase complement(2943006..2944190) Bacillus subtilis subsp. subtilis str. 168 938011 NP_390755.1 CDS araL NC_000964.3 2944187 2945005 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme; arabinose operon protein AraL complement(2944187..2945005) Bacillus subtilis subsp. subtilis str. 168 937431 NP_390756.1 CDS araD NC_000964.3 2944983 2945672 R catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase complement(2944983..2945672) Bacillus subtilis subsp. subtilis str. 168 937894 NP_390757.1 CDS araB NC_000964.3 2945689 2947371 R catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase complement(2945689..2947371) Bacillus subtilis subsp. subtilis str. 168 936019 NP_390758.2 CDS araA NC_000964.3 2947385 2948875 R catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase complement(2947385..2948875) Bacillus subtilis subsp. subtilis str. 168 936764 NP_390759.2 CDS abnA NC_000964.3 2949053 2950024 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14973026; Product type e: enzyme; arabinan-endo 1,5-alpha-L-arabinase complement(2949053..2950024) Bacillus subtilis subsp. subtilis str. 168 937430 NP_390760.1 CDS ysdC NC_000964.3 2950221 2951306 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase complement(2950221..2951306) Bacillus subtilis subsp. subtilis str. 168 936750 NP_390761.1 CDS ysdB NC_000964.3 2951490 2951882 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10960106; sigma-W pathway protein YsdB 2951490..2951882 Bacillus subtilis subsp. subtilis str. 168 937429 NP_390762.1 CDS ysdA NC_000964.3 2951898 2952167 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein complement(2951898..2952167) Bacillus subtilis subsp. subtilis str. 168 937419 NP_390763.1 CDS rplT NC_000964.3 2952224 2952583 R binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 complement(2952224..2952583) Bacillus subtilis subsp. subtilis str. 168 936645 NP_390764.1 CDS rpmI NC_000964.3 2952615 2952815 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17289755, 8722036; Product type s : structure; 50S ribosomal protein L35 complement(2952615..2952815) Bacillus subtilis subsp. subtilis str. 168 937421 NP_390765.1 CDS infC NC_000964.3 2952828 2953349 R IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 complement(2952828..2953349) Bacillus subtilis subsp. subtilis str. 168 937835 NP_390767.2 CDS yscB NC_000964.3 2953795 2954460 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type lp : lipoprotein; hypothetical protein 2953795..2954460 Bacillus subtilis subsp. subtilis str. 168 936599 NP_390768.1 CDS ysbB NC_000964.3 2954492 2955187 R in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB complement(2954492..2955187) Bacillus subtilis subsp. subtilis str. 168 937418 NP_390769.1 CDS ysbA NC_000964.3 2955209 2955649 R negatively regulates murein hydrolase activity; antiholin-like protein LrgA complement(2955209..2955649) Bacillus subtilis subsp. subtilis str. 168 937417 NP_390770.1 CDS lytT NC_000964.3 2955783 2956508 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12034833, 12914674; Product type r: regulator; sensory transduction protein LytT complement(2955783..2956508) Bacillus subtilis subsp. subtilis str. 168 936931 NP_390771.1 CDS lytS NC_000964.3 2956486 2958267 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12914674; Product type rc : receptor; sensor protein LytS complement(2956486..2958267) Bacillus subtilis subsp. subtilis str. 168 937404 NP_390772.2 CDS ysaA NC_000964.3 2958434 2959216 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YsaA 2958434..2959216 Bacillus subtilis subsp. subtilis str. 168 936546 NP_390773.1 CDS thrS NC_000964.3 2959257 2961188 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonine--tRNA ligase 1 complement(2959257..2961188) Bacillus subtilis subsp. subtilis str. 168 937410 NP_390774.2 CDS ytxC NC_000964.3 2961586 2962431 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2961586..2962431) Bacillus subtilis subsp. subtilis str. 168 937401 NP_390775.1 CDS ytxB NC_000964.3 2962510 2963151 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; tvp38/tmem64 family membrane protein YtxB complement(2962510..2963151) Bacillus subtilis subsp. subtilis str. 168 937403 NP_390776.1 CDS dnaI NC_000964.3 2963185 2964120 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(2963185..2964120) Bacillus subtilis subsp. subtilis str. 168 936873 NP_390777.1 CDS dnaB NC_000964.3 2964148 2965566 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15186423, 16002087, 17289076; Product type f: factor; replication initiation and membrane attachment protein complement(2964148..2965566) Bacillus subtilis subsp. subtilis str. 168 937396 NP_390778.1 CDS nrdR NC_000964.3 2965681 2966139 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16950922; Product type r: regulator; transcriptional repressor NrdR complement(2965681..2966139) Bacillus subtilis subsp. subtilis str. 168 937402 NP_390779.2 CDS speD NC_000964.3 2966413 2966793 R Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase proenzyme complement(2966413..2966793) Bacillus subtilis subsp. subtilis str. 168 936773 NP_390780.1 CDS gapB NC_000964.3 2967032 2968054 R NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis; glyceraldehyde-3-phosphate dehydrogenase 2 complement(2967032..2968054) Bacillus subtilis subsp. subtilis str. 168 937393 NP_390781.1 CDS ytcD NC_000964.3 2968260 2968640 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator complement(2968260..2968640) Bacillus subtilis subsp. subtilis str. 168 936607 NP_390782.1 CDS ytbD NC_000964.3 2968824 2970014 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 2968824..2970014 Bacillus subtilis subsp. subtilis str. 168 936655 NP_390783.1 CDS ytbE NC_000964.3 2970038 2970880 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2970038..2970880 Bacillus subtilis subsp. subtilis str. 168 937384 NP_390784.1 CDS coaE NC_000964.3 2970922 2971515 R catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase complement(2970922..2971515) Bacillus subtilis subsp. subtilis str. 168 937388 NP_390785.2 CDS ytaF NC_000964.3 2971531 2972163 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(2971531..2972163) Bacillus subtilis subsp. subtilis str. 168 937389 NP_390786.2 CDS mutM NC_000964.3 2972329 2973159 R Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase complement(2972329..2973159) Bacillus subtilis subsp. subtilis str. 168 936741 NP_390787.1 CDS polA NC_000964.3 2973182 2975824 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(2973182..2975824) Bacillus subtilis subsp. subtilis str. 168 936617 NP_390788.1 CDS phoR NC_000964.3 2976068 2977807 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10433720, 12486063, 14762014, 15205429, 16452408, 17085571; Product type rc : receptor; alkaline phosphatase synthesis sensor protein PhoR complement(2976068..2977807) Bacillus subtilis subsp. subtilis str. 168 937387 NP_390789.2 CDS phoP NC_000964.3 2977800 2978522 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762014, 14973033, 15205429, 16030210, 16452408, 16816204; Product type r: regulator; alkaline phosphatase synthesis transcriptional regulatory protein PhoP complement(2977800..2978522) Bacillus subtilis subsp. subtilis str. 168 936644 NP_390790.1 CDS mdh NC_000964.3 2978734 2979672 R Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase complement(2978734..2979672) Bacillus subtilis subsp. subtilis str. 168 937385 NP_390791.1 CDS icd NC_000964.3 2979716 2980987 R Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase complement(2979716..2980987) Bacillus subtilis subsp. subtilis str. 168 938183 NP_390792.1 CDS citZ NC_000964.3 2981151 2982269 R catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 2 complement(2981151..2982269) Bacillus subtilis subsp. subtilis str. 168 937381 NP_390793.1 CDS ytwI NC_000964.3 2982603 2983067 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(2982603..2983067) Bacillus subtilis subsp. subtilis str. 168 935947 NP_390794.1 CDS ytvI NC_000964.3 2983164 2984279 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type pt: transporter; hypothetical protein 2983164..2984279 Bacillus subtilis subsp. subtilis str. 168 937380 NP_390795.1 CDS fxsA NC_000964.3 2984312 2984695 R F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; hypothetical protein complement(2984312..2984695) Bacillus subtilis subsp. subtilis str. 168 937382 NP_390796.1 CDS pyk NC_000964.3 2984788 2986545 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase complement(2984788..2986545) Bacillus subtilis subsp. subtilis str. 168 936596 NP_390797.1 CDS pfkA NC_000964.3 2986588 2987547 R catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase complement(2986588..2987547) Bacillus subtilis subsp. subtilis str. 168 937376 NP_390798.1 CDS accA NC_000964.3 2987731 2988708 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha complement(2987731..2988708) Bacillus subtilis subsp. subtilis str. 168 936367 NP_390799.2 CDS accD NC_000964.3 2988693 2989565 R catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta complement(2988693..2989565) Bacillus subtilis subsp. subtilis str. 168 936186 NP_390800.1 CDS ytsJ NC_000964.3 2989900 2991132 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme; NAD-dependent malic enzyme 4 complement(2989900..2991132) Bacillus subtilis subsp. subtilis str. 168 937378 NP_390801.1 CDS dnaE NC_000964.3 2991269 2994616 R catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III subunit alpha complement(2991269..2994616) Bacillus subtilis subsp. subtilis str. 168 936593 YP_003097771.1 CDS ytrH NC_000964.3 2994756 2995097 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype; sporulation membrane protein YtrH 2994756..2995097 Bacillus subtilis subsp. subtilis str. 168 8303067 NP_390802.2 CDS ytrI NC_000964.3 2995067 2995597 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype; sporulation protein 2995067..2995597 Bacillus subtilis subsp. subtilis str. 168 937371 YP_003097772.1 CDS ytzJ NC_000964.3 2995699 2995890 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2995699..2995890 Bacillus subtilis subsp. subtilis str. 168 8303031 NP_390803.1 CDS nrnA NC_000964.3 2995908 2996849 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17586819; Product type e: enzyme; bifunctional oligoribonuclease and PAP phosphatase NrnA complement(2995908..2996849) Bacillus subtilis subsp. subtilis str. 168 935963 NP_390804.1 CDS ytpI NC_000964.3 2996980 2997282 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2996980..2997282 Bacillus subtilis subsp. subtilis str. 168 937370 NP_390805.1 CDS ytoI NC_000964.3 2997301 2998620 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(2997301..2998620) Bacillus subtilis subsp. subtilis str. 168 935941 NP_390806.1 CDS ytnM NC_000964.3 2998796 2999698 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(2998796..2999698) Bacillus subtilis subsp. subtilis str. 168 937366 NP_390807.1 CDS ytnL NC_000964.3 2999717 3000967 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10588044, 10939241, 11423008, 16109943; Product type pe: enzyme; hydrolase YtnL complement(2999717..3000967) Bacillus subtilis subsp. subtilis str. 168 936157 NP_390808.1 CDS rbfK NC_000964.3 3000985 3001677 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15668000, 16109943, 17590224; Product type e: enzyme; RNA-binding riboflavin kinase RibR complement(3000985..3001677) Bacillus subtilis subsp. subtilis str. 168 937367 NP_390809.1 CDS ytnJ NC_000964.3 3001724 3003052 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; monooxygenase MoxC complement(3001724..3003052) Bacillus subtilis subsp. subtilis str. 168 937365 NP_390810.1 CDS ytnI NC_000964.3 3003049 3003330 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; glutaredoxin YtnI complement(3003049..3003330) Bacillus subtilis subsp. subtilis str. 168 936632 NP_390811.1 CDS ytmO NC_000964.3 3003345 3004349 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; hypothetical protein complement(3003345..3004349) Bacillus subtilis subsp. subtilis str. 168 936618 NP_390812.1 CDS tcyN NC_000964.3 3004346 3005125 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine import ATP-binding protein TcyN complement(3004346..3005125) Bacillus subtilis subsp. subtilis str. 168 937364 NP_390813.1 CDS tcyM NC_000964.3 3005122 3005829 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter; L-cystine transport system permease protein TcyM complement(3005122..3005829) Bacillus subtilis subsp. subtilis str. 168 935938 NP_390814.1 CDS tcyL NC_000964.3 3005859 3006578 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter; L-cystine transport system permease protein TcyL complement(3005859..3006578) Bacillus subtilis subsp. subtilis str. 168 936115 NP_390815.1 CDS tcyK NC_000964.3 3006600 3007412 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine-binding protein TcyK complement(3006600..3007412) Bacillus subtilis subsp. subtilis str. 168 937359 NP_390816.1 CDS tcyJ NC_000964.3 3007426 3008235 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine-binding protein TcyJ complement(3007426..3008235) Bacillus subtilis subsp. subtilis str. 168 937354 NP_390817.1 CDS ytmI NC_000964.3 3008249 3008785 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 11423008, 16109943; Product type pe: enzyme; N-acetyltransferase YtmI complement(3008249..3008785) Bacillus subtilis subsp. subtilis str. 168 937353 NP_390818.1 CDS ytlI NC_000964.3 3008938 3009864 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 11423008, 16109943, 16513748; Product type r: regulator; LysR family transcriptional regulator 3008938..3009864 Bacillus subtilis subsp. subtilis str. 168 938452 NP_390819.2 CDS ytkL NC_000964.3 3009915 3010598 R catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase complement(3009915..3010598) Bacillus subtilis subsp. subtilis str. 168 936598 NP_390820.1 CDS fabG NC_000964.3 3010661 3011428 R catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase complement(3010661..3011428) Bacillus subtilis subsp. subtilis str. 168 937351 NP_390821.2 CDS ytzD NC_000964.3 3011555 3011689 R Evidence 5: No homology to any previously reported sequences; PubMedId: 11423008; hypothetical protein complement(3011555..3011689) Bacillus subtilis subsp. subtilis str. 168 936667 NP_390822.1 CDS argH NC_000964.3 3011751 3013136 R catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase complement(3011751..3013136) Bacillus subtilis subsp. subtilis str. 168 937966 NP_390823.1 CDS argG NC_000964.3 3013133 3014344 R catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase complement(3013133..3014344) Bacillus subtilis subsp. subtilis str. 168 937348 NP_390824.1 CDS moaB NC_000964.3 3014514 3015026 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15269205; Product type f: factor; molybdenum cofactor biosynthesis protein B complement(3014514..3015026) Bacillus subtilis subsp. subtilis str. 168 937349 NP_390825.1 CDS ackA NC_000964.3 3015111 3016298 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(3015111..3016298) Bacillus subtilis subsp. subtilis str. 168 937347 NP_390826.1 CDS ytxK NC_000964.3 3016646 3017635 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3016646..3017635) Bacillus subtilis subsp. subtilis str. 168 938186 NP_390827.1 CDS tpx NC_000964.3 3017696 3018199 R antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase complement(3017696..3018199) Bacillus subtilis subsp. subtilis str. 168 937688 NP_390828.1 CDS ytfJ NC_000964.3 3018309 3018764 R Evidence 4: Homologs of previously reported genes of unknown function; spore protein YtfJ complement(3018309..3018764) Bacillus subtilis subsp. subtilis str. 168 937346 NP_390829.1 CDS ytfI NC_000964.3 3018778 3019458 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3018778..3019458) Bacillus subtilis subsp. subtilis str. 168 937342 NP_390830.1 CDS yteJ NC_000964.3 3019533 3020027 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3019533..3020027) Bacillus subtilis subsp. subtilis str. 168 937343 NP_390831.1 CDS sppA NC_000964.3 3020040 3021047 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 16484219, 9987136; Product type e: enzyme; signal peptide peptidase SppA complement(3020040..3021047) Bacillus subtilis subsp. subtilis str. 168 937679 NP_390832.1 CDS ppnK NC_000964.3 3021233 3022036 D catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2 3021233..3022036 Bacillus subtilis subsp. subtilis str. 168 936767 NP_390833.1 CDS ytcJ NC_000964.3 3022068 3023657 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amidohydrolase YtcJ complement(3022068..3023657) Bacillus subtilis subsp. subtilis str. 168 936723 NP_390834.2 CDS ytcI NC_000964.3 3023677 3025266 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl--CoA ligase complement(3023677..3025266) Bacillus subtilis subsp. subtilis str. 168 937336 NP_390835.1 CDS sspA NC_000964.3 3025445 3025654 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 2456528, 2468649, 3009398; Product type cp: cell process; small acid-soluble spore protein A complement(3025445..3025654) Bacillus subtilis subsp. subtilis str. 168 937338 NP_390836.2 CDS ytbJ NC_000964.3 3025748 3026953 R Required for the synthesis of the thiazole moiety; tRNA sulfurtransferase complement(3025748..3026953) Bacillus subtilis subsp. subtilis str. 168 937471 NP_390837.1 CDS iscS NC_000964.3 3026957 3028102 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 11443125, 13129955, 14757766, 16388576, 17237162; Product type e: enzyme; cysteine desulfurase IscS 2 complement(3026957..3028102) Bacillus subtilis subsp. subtilis str. 168 937701 NP_390838.1 CDS braB NC_000964.3 3028297 3029634 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11528000, 15849754, 16850406; Product type t : transporter; branched-chain amino acid transport system carrier protein BraB 3028297..3029634 Bacillus subtilis subsp. subtilis str. 168 937334 NP_390839.1 CDS ezrA NC_000964.3 3029729 3031417 R acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA complement(3029729..3031417) Bacillus subtilis subsp. subtilis str. 168 937337 NP_390840.1 CDS hisJ NC_000964.3 3031614 3032420 D catalyzes the formation of L-histidinol from L-histidinol phosphate; histidinol-phosphatase 3031614..3032420 Bacillus subtilis subsp. subtilis str. 168 937924 NP_390841.1 CDS yttP NC_000964.3 3032417 3033040 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pr : regulator; TetR family transcriptional regulator complement(3032417..3033040) Bacillus subtilis subsp. subtilis str. 168 937327 NP_390842.2 CDS ytsP NC_000964.3 3033167 3033658 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3033167..3033658 Bacillus subtilis subsp. subtilis str. 168 936758 NP_390843.1 CDS dgcP NC_000964.3 3033696 3035435 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; diguanylate cyclase complement(3033696..3035435) Bacillus subtilis subsp. subtilis str. 168 936255 NP_390844.1 CDS rpsD NC_000964.3 3035730 3036332 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3035730..3036332 Bacillus subtilis subsp. subtilis str. 168 937319 NP_390845.1 CDS tyrS NC_000964.3 3036603 3037871 R catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosine--tRNA ligase 1 complement(3036603..3037871) Bacillus subtilis subsp. subtilis str. 168 938185 YP_003097773.1 CDS ytzK NC_000964.3 3038060 3038203 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3038060..3038203) Bacillus subtilis subsp. subtilis str. 168 8303078 NP_390846.1 CDS acsA NC_000964.3 3038213 3039931 R Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-coenzyme A synthetase complement(3038213..3039931) Bacillus subtilis subsp. subtilis str. 168 937324 NP_390847.1 CDS acuA NC_000964.3 3040092 3040724 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 18487328, 7934817; Product type e : enzyme; acetoin utilization protein AcuA 3040092..3040724 Bacillus subtilis subsp. subtilis str. 168 937633 NP_390848.1 CDS acuB NC_000964.3 3040751 3041395 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type f: factor; acetoin utilization protein AcuB 3040751..3041395 Bacillus subtilis subsp. subtilis str. 168 937318 NP_390849.1 CDS acuC NC_000964.3 3041392 3042555 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type e: enzyme; acetoin utilization protein AcuC 3041392..3042555 Bacillus subtilis subsp. subtilis str. 168 936834 NP_390850.1 CDS ytxE NC_000964.3 3042566 3043294 R Homolog of MotB, appears to be involved in motility on surfaces or under specific ionic conditions. With MotP (a Mot A homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; hypothetical protein complement(3042566..3043294) Bacillus subtilis subsp. subtilis str. 168 937315 NP_390851.1 CDS ytxD NC_000964.3 3043284 3044102 R Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; hypothetical protein complement(3043284..3044102) Bacillus subtilis subsp. subtilis str. 168 937317 NP_390852.1 CDS ccpA NC_000964.3 3044165 3045169 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11931564, 14665673, 16316990, 17085448; Product type r: regulator; catabolite control protein A complement(3044165..3045169) Bacillus subtilis subsp. subtilis str. 168 935942 NP_390853.1 CDS aroA NC_000964.3 3045445 3046521 R catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; 5-enolpyruvylshikimate-3-phosphate synthetase AroA complement(3045445..3046521) Bacillus subtilis subsp. subtilis str. 168 937853 NP_390854.1 CDS ytxJ NC_000964.3 3046757 3047083 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232; hypothetical protein complement(3046757..3047083) Bacillus subtilis subsp. subtilis str. 168 937308 NP_390855.2 CDS ytxH NC_000964.3 3047107 3047562 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232; hypothetical protein complement(3047107..3047562) Bacillus subtilis subsp. subtilis str. 168 937312 NP_390856.2 CDS ytxG NC_000964.3 3047593 3048015 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232; hypothetical protein complement(3047593..3048015) Bacillus subtilis subsp. subtilis str. 168 937386 NP_390857.1 CDS murC NC_000964.3 3048177 3049475 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(3048177..3049475) Bacillus subtilis subsp. subtilis str. 168 937311 NP_390859.2 CDS ytpS NC_000964.3 3049725 3052583 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11134515, 11208805, 3129532; Product type pe: enzyme; DNA translocase SftA complement(3049725..3052583) Bacillus subtilis subsp. subtilis str. 168 938522 NP_390860.1 CDS ytpR NC_000964.3 3052743 3053348 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; tRNA-binding protein YtpR complement(3052743..3053348) Bacillus subtilis subsp. subtilis str. 168 937964 NP_390861.1 CDS ytpQ NC_000964.3 3053364 3054173 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520; hypothetical protein complement(3053364..3054173) Bacillus subtilis subsp. subtilis str. 168 937506 NP_390862.1 CDS ytpP NC_000964.3 3054188 3054511 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12719520, 15937154; Product type pe: enzyme; thioredoxin complement(3054188..3054511) Bacillus subtilis subsp. subtilis str. 168 936697 NP_390863.1 CDS ytoQ NC_000964.3 3054746 3055192 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3054746..3055192 Bacillus subtilis subsp. subtilis str. 168 937302 NP_390864.1 CDS ytoP NC_000964.3 3055247 3056320 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8535515; Product type e: enzyme; aminopeptidase YtoP complement(3055247..3056320) Bacillus subtilis subsp. subtilis str. 168 937301 NP_390865.1 CDS ytzB NC_000964.3 3056479 3056796 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3056479..3056796 Bacillus subtilis subsp. subtilis str. 168 937300 NP_390866.1 CDS malS NC_000964.3 3056849 3058549 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; NAD-dependent malic enzyme 3 complement(3056849..3058549) Bacillus subtilis subsp. subtilis str. 168 938071 NP_390867.1 CDS ytnP NC_000964.3 3058631 3059401 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3058631..3059401) Bacillus subtilis subsp. subtilis str. 168 937981 NP_390868.1 CDS trmB NC_000964.3 3059547 3060188 R tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase complement(3059547..3060188) Bacillus subtilis subsp. subtilis str. 168 936447 NP_390869.1 CDS ytzH NC_000964.3 3060395 3060673 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3060395..3060673 Bacillus subtilis subsp. subtilis str. 168 937298 NP_390870.2 CDS ytmP NC_000964.3 3060674 3061288 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11545674, 9026440; Product type pe: enzyme; phosphotransferase YtmP complement(3060674..3061288) Bacillus subtilis subsp. subtilis str. 168 936622 NP_390871.2 CDS amyX NC_000964.3 3061651 3063807 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16582490, 9453151; Product type e: enzyme; pullulanase complement(3061651..3063807) Bacillus subtilis subsp. subtilis str. 168 937292 NP_390872.1 CDS ytlR NC_000964.3 3063833 3064762 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipid kinase YtlR complement(3063833..3064762) Bacillus subtilis subsp. subtilis str. 168 937289 NP_390873.1 CDS ytlQ NC_000964.3 3064811 3065725 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3064811..3065725) Bacillus subtilis subsp. subtilis str. 168 938075 NP_390874.1 CDS ytlP NC_000964.3 3065751 3066302 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17012785; Product type s: structure; hypothetical protein complement(3065751..3066302) Bacillus subtilis subsp. subtilis str. 168 937293 NP_390875.1 CDS ytkP NC_000964.3 3066451 3067386 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16267287; Product type pe: enzyme; cysteine synthase 3066451..3067386 Bacillus subtilis subsp. subtilis str. 168 936733 NP_390876.1 CDS ytjP NC_000964.3 3067420 3068811 R divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase YtjP complement(3067420..3068811) Bacillus subtilis subsp. subtilis str. 168 937290 NP_390877.1 CDS pbuO NC_000964.3 3068908 3070206 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 15849754, 16850406; Product type t: transporter; guanine/hypoxanthine permease PbuO 3068908..3070206 Bacillus subtilis subsp. subtilis str. 168 938070 NP_390878.1 CDS ythQ NC_000964.3 3070246 3071403 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(3070246..3071403) Bacillus subtilis subsp. subtilis str. 168 937288 NP_390879.1 CDS ythP NC_000964.3 3071400 3072110 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein complement(3071400..3072110) Bacillus subtilis subsp. subtilis str. 168 937282 NP_390880.1 CDS ytzE NC_000964.3 3072401 3072622 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618461; Product type pr : regulator; DeoR family transcriptional regulator 3072401..3072622 Bacillus subtilis subsp. subtilis str. 168 937281 NP_390882.2 CDS ytzG NC_000964.3 3072743 3073462 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA pseudouridine synthase complement(3072743..3073462) Bacillus subtilis subsp. subtilis str. 168 936165 NP_390883.1 CDS ytgP NC_000964.3 3073531 3075165 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11254558, 15044829, 15849754, 16850406; Product type pe: enzyme; cell division protein YtgP complement(3073531..3075165) Bacillus subtilis subsp. subtilis str. 168 937937 NP_390884.2 CDS ytfP NC_000964.3 3075367 3076629 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3075367..3076629 Bacillus subtilis subsp. subtilis str. 168 937280 NP_390885.1 CDS opuD NC_000964.3 3076818 3078356 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14996799, 15849754, 16850406, 8752321, 9925583; Product type t: transporter; glycine betaine transporter OpuD 3076818..3078356 Bacillus subtilis subsp. subtilis str. 168 937986 NP_390886.1 CDS yteV NC_000964.3 3078393 3078575 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8990290; sporulation protein cse60 complement(3078393..3078575) Bacillus subtilis subsp. subtilis str. 168 937278 NP_390887.1 CDS yteU NC_000964.3 3078643 3079311 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pe: enzyme; hypothetical protein complement(3078643..3079311) Bacillus subtilis subsp. subtilis str. 168 936405 NP_390888.1 CDS yteT NC_000964.3 3079333 3080619 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type pe : enzyme; oxidoreductase complement(3079333..3080619) Bacillus subtilis subsp. subtilis str. 168 937274 NP_390889.2 CDS yteS NC_000964.3 3080631 3081134 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type lp : lipoprotein; lipoprotein complement(3080631..3081134) Bacillus subtilis subsp. subtilis str. 168 937272 NP_390890.2 CDS yteR NC_000964.3 3081131 3082243 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15148314, 15906318, 16781735, 16870154, 17449691; Product type e: enzyme; rhamnogalacturonyl hydrolase complement(3081131..3082243) Bacillus subtilis subsp. subtilis str. 168 937273 NP_390892.2 CDS yteP NC_000964.3 3082260 3083225 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; multiple-sugar transport system permease YteP complement(3082260..3083225) Bacillus subtilis subsp. subtilis str. 168 937271 NP_390893.1 CDS ytdP NC_000964.3 3083441 3085759 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 3083441..3085759 Bacillus subtilis subsp. subtilis str. 168 936234 NP_390894.3 CDS ytcQ NC_000964.3 3085800 3087296 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; peptide ABC transporter substrate-binding protein complement(3085800..3087296) Bacillus subtilis subsp. subtilis str. 168 938090 NP_390895.1 CDS ytcP NC_000964.3 3087321 3088181 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease complement(3087321..3088181) Bacillus subtilis subsp. subtilis str. 168 938095 NP_390896.2 CDS ytbQ NC_000964.3 3088388 3089149 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3088388..3089149) Bacillus subtilis subsp. subtilis str. 168 937270 NP_390897.1 CDS bioI NC_000964.3 3089226 3090413 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11368323; Product type e: enzyme; biotin biosynthesis cytochrome P450 complement(3089226..3090413) Bacillus subtilis subsp. subtilis str. 168 935928 NP_390898.1 CDS bioB NC_000964.3 3090482 3091489 R catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase complement(3090482..3091489) Bacillus subtilis subsp. subtilis str. 168 938180 NP_390899.1 CDS bioD NC_000964.3 3091492 3092187 R DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; ATP-dependent dethiobiotin synthetase BioD complement(3091492..3092187) Bacillus subtilis subsp. subtilis str. 168 937264 NP_390900.1 CDS bioF NC_000964.3 3092184 3093353 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717296, 12368242, 8763940; Product type e: enzyme; 8-amino-7-oxononanoate synthase complement(3092184..3093353) Bacillus subtilis subsp. subtilis str. 168 937268 NP_390901.1 CDS bioA NC_000964.3 3093343 3094689 R catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; L-lysine-8-amino-7-oxononanoate aminotransferase complement(3093343..3094689) Bacillus subtilis subsp. subtilis str. 168 936286 NP_390902.3 CDS bioW NC_000964.3 3094679 3095455 R catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A; 6-carboxyhexanoate--CoA ligase complement(3094679..3095455) Bacillus subtilis subsp. subtilis str. 168 938017 NP_390903.1 CDS ytaP NC_000964.3 3095665 3096564 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YtaP complement(3095665..3096564) Bacillus subtilis subsp. subtilis str. 168 937263 NP_390904.1 CDS msmR NC_000964.3 3096782 3097816 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288; Product type r: regulator; LacI family transcriptional regulator 3096782..3097816 Bacillus subtilis subsp. subtilis str. 168 937257 NP_390905.1 CDS msmE NC_000964.3 3097850 3099130 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 16707683; Product type lp : lipoprotein; sugar ABC transporter substrate-binding protein 3097850..3099130 Bacillus subtilis subsp. subtilis str. 168 936693 NP_390906.1 CDS amyD NC_000964.3 3099123 3100034 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 1537846, 15849754, 16707683, 16850406; Product type t: transporter; ABC transporter permease 3099123..3100034 Bacillus subtilis subsp. subtilis str. 168 937258 NP_390907.1 CDS amyC NC_000964.3 3100031 3100861 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1537846, 15849754, 16707683, 16850406; Product type t: transporter; ABC transporter permease 3100031..3100861 Bacillus subtilis subsp. subtilis str. 168 935927 NP_390908.1 CDS melA NC_000964.3 3100881 3102179 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12847288; Product type e: enzyme; alpha-galactosidase 3100881..3102179 Bacillus subtilis subsp. subtilis str. 168 937255 NP_390909.2 CDS ytwF NC_000964.3 3102201 3102512 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme; hypothetical protein complement(3102201..3102512) Bacillus subtilis subsp. subtilis str. 168 936589 NP_390910.1 CDS leuS NC_000964.3 3102629 3105043 R leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucine--tRNA ligase complement(3102629..3105043) Bacillus subtilis subsp. subtilis str. 168 938102 NP_390911.2 CDS ytvB NC_000964.3 3105470 3105799 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16923906; Product type pm : membrane component; hypothetical protein complement(3105470..3105799) Bacillus subtilis subsp. subtilis str. 168 937249 NP_390912.1 CDS ytvA NC_000964.3 3106210 3106995 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11964249, 16923906, 16923909, 17200735, 17443319, 17575448; Product type rc : receptor; blue-light photoreceptor 3106210..3106995 Bacillus subtilis subsp. subtilis str. 168 937254 NP_390913.1 CDS yttB NC_000964.3 3107232 3108425 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534, 15849754, 16850406; Product type pt: transporter; MFS transporter complement(3107232..3108425) Bacillus subtilis subsp. subtilis str. 168 936526 NP_390914.2 CDS yttA NC_000964.3 3108614 3109360 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818; membrane protein 3108614..3109360 Bacillus subtilis subsp. subtilis str. 168 937248 NP_390915.1 CDS bceB NC_000964.3 3109397 3111337 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 15849754, 16850406, 17905982; Product type t: transporter; bacitracin export permease protein BceB complement(3109397..3111337) Bacillus subtilis subsp. subtilis str. 168 938178 NP_390916.1 CDS bceA NC_000964.3 3111327 3112088 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 17905982; Product type t: transporter; bacitracin export ATP-binding protein BceA complement(3111327..3112088) Bacillus subtilis subsp. subtilis str. 168 937246 NP_390917.1 CDS bceS NC_000964.3 3112190 3113194 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type rc: receptor; sensor protein BceS complement(3112190..3113194) Bacillus subtilis subsp. subtilis str. 168 936816 NP_390918.1 CDS bceR NC_000964.3 3113187 3113882 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type r: regulator; sensory transduction protein BceR complement(3113187..3113882) Bacillus subtilis subsp. subtilis str. 168 936307 NP_390919.1 CDS ytrF NC_000964.3 3113979 3115289 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease complement(3113979..3115289) Bacillus subtilis subsp. subtilis str. 168 937247 NP_390920.1 CDS ytrE NC_000964.3 3115279 3115974 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter; ABC transporter ATP-binding protein complement(3115279..3115974) Bacillus subtilis subsp. subtilis str. 168 937245 NP_390921.1 CDS ytrD NC_000964.3 3115989 3116966 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease complement(3115989..3116966) Bacillus subtilis subsp. subtilis str. 168 936438 NP_390922.1 CDS ytrC NC_000964.3 3116996 3117982 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease complement(3116996..3117982) Bacillus subtilis subsp. subtilis str. 168 937243 NP_390923.1 CDS ytrB NC_000964.3 3117976 3118854 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter; ABC transporter ATP-binding protein complement(3117976..3118854) Bacillus subtilis subsp. subtilis str. 168 936641 NP_390924.1 CDS ytrA NC_000964.3 3118847 3119239 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 11756427, 17194626; Product type r: regulator; GntR family transcriptional regulator complement(3118847..3119239) Bacillus subtilis subsp. subtilis str. 168 937244 NP_390925.1 CDS ytzC NC_000964.3 3119565 3119837 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3119565..3119837) Bacillus subtilis subsp. subtilis str. 168 936521 NP_390926.1 CDS ytqA NC_000964.3 3119999 3120967 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; radical SAM protein YtqA 3119999..3120967 Bacillus subtilis subsp. subtilis str. 168 937240 NP_390927.1 CDS ytqB NC_000964.3 3120964 3121548 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; rRNA methylase YtqB 3120964..3121548 Bacillus subtilis subsp. subtilis str. 168 938058 NP_390928.1 CDS ytpB NC_000964.3 3121538 3122641 R Evidence 4: Homologs of previously reported genes of unknown function; tetraprenyl-beta-curcumene synthase complement(3121538..3122641) Bacillus subtilis subsp. subtilis str. 168 936222 NP_390929.1 CDS ytpA NC_000964.3 3122662 3123441 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11796336; Product type e: enzyme; phospholipase YtpA complement(3122662..3123441) Bacillus subtilis subsp. subtilis str. 168 937237 NP_390930.1 CDS ytoA NC_000964.3 3123490 3124005 D Evidence 4: Homologs of previously reported genes of unknown function; transferase YtoA 3123490..3124005 Bacillus subtilis subsp. subtilis str. 168 937238 NP_390931.1 CDS ytnA NC_000964.3 3124250 3125641 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10498721, 15849754, 16850406; Product type pt: transporter; amino acid permease YtnA complement(3124250..3125641) Bacillus subtilis subsp. subtilis str. 168 938118 NP_390932.1 CDS asnB NC_000964.3 3125777 3127675 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme; asparagine synthetase 1 complement(3125777..3127675) Bacillus subtilis subsp. subtilis str. 168 937236 NP_390933.1 CDS metK NC_000964.3 3127825 3129027 R catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthase complement(3127825..3129027) Bacillus subtilis subsp. subtilis str. 168 937090 NP_390934.2 CDS pckA NC_000964.3 3129530 3131113 D PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3129530..3131113 Bacillus subtilis subsp. subtilis str. 168 937235 NP_390935.1 CDS ytmB NC_000964.3 3131152 3131394 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3131152..3131394) Bacillus subtilis subsp. subtilis str. 168 937228 NP_390936.1 CDS ytmA NC_000964.3 3131446 3132219 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YtmA complement(3131446..3132219) Bacillus subtilis subsp. subtilis str. 168 936383 NP_390937.2 CDS ytlA NC_000964.3 3132370 3133374 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; binding protein YtlA 3132370..3133374 Bacillus subtilis subsp. subtilis str. 168 935959 NP_390939.1 CDS ytlC NC_000964.3 3133387 3134169 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3133387..3134169 Bacillus subtilis subsp. subtilis str. 168 937218 NP_390940.1 CDS ytlD NC_000964.3 3134144 3134956 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3134144..3134956 Bacillus subtilis subsp. subtilis str. 168 937097 NP_390941.1 CDS ytkD NC_000964.3 3134983 3135459 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576788, 16513759; Product type e: enzyme; 8-oxo-dGTP diphosphatase YtkD complement(3134983..3135459) Bacillus subtilis subsp. subtilis str. 168 937072 NP_390942.1 CDS ytkC NC_000964.3 3135668 3136072 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type h: extrachromosomal origin; hypothetical protein complement(3135668..3136072) Bacillus subtilis subsp. subtilis str. 168 937209 NP_390943.1 CDS dps NC_000964.3 3136238 3136675 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12767829, 16091047, 16861227, 16935006; Product type e: enzyme; general stress protein 20U complement(3136238..3136675) Bacillus subtilis subsp. subtilis str. 168 937211 YP_003097774.1 CDS ytzI NC_000964.3 3136768 3136944 D Evidence 5: No homology to any previously reported sequences; membrane protein 3136768..3136944 Bacillus subtilis subsp. subtilis str. 168 8302972 NP_390944.1 CDS ytkA NC_000964.3 3136938 3137375 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein complement(3136938..3137375) Bacillus subtilis subsp. subtilis str. 168 937181 NP_390945.1 CDS luxS NC_000964.3 3137495 3137968 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteine lyase complement(3137495..3137968) Bacillus subtilis subsp. subtilis str. 168 937106 NP_390946.1 CDS ytjA NC_000964.3 3138097 3138324 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein insertion efficiency factor 3138097..3138324 Bacillus subtilis subsp. subtilis str. 168 937207 NP_390947.1 CDS ytiB NC_000964.3 3138321 3138884 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12193617; Product type e: enzyme; carbonic anhydrase YtiB complement(3138321..3138884) Bacillus subtilis subsp. subtilis str. 168 938087 NP_390948.1 CDS rpmE2 NC_000964.3 3138978 3139226 R RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B complement(3138978..3139226) Bacillus subtilis subsp. subtilis str. 168 937208 NP_390949.2 CDS ythA NC_000964.3 3139431 3140762 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17114254, 9852001; Product type pe: enzyme; cytochrome bd menaquinol oxidase subunit I 3139431..3140762 Bacillus subtilis subsp. subtilis str. 168 937142 NP_390950.1 CDS ythB NC_000964.3 3140806 3141846 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11073895, 15576792, 15849754, 16850406; Product type pe: enzyme; cytochrome bd menaquinol oxidase subunit II 3140806..3141846 Bacillus subtilis subsp. subtilis str. 168 937206 YP_003097775.1 CDS ytzL NC_000964.3 3141900 3142058 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3141900..3142058 Bacillus subtilis subsp. subtilis str. 168 8303158 NP_390952.1 CDS mntD NC_000964.3 3142077 3142964 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16566604, 16704341, 16850406; Product type t : transporter; manganese transport system membrane protein MntD complement(3142077..3142964) Bacillus subtilis subsp. subtilis str. 168 937149 NP_390953.1 CDS mntC NC_000964.3 3142954 3144261 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16704341, 16850406; Product type t: transporter; manganese transport system membrane protein MntC complement(3142954..3144261) Bacillus subtilis subsp. subtilis str. 168 937203 NP_390954.1 CDS mntB NC_000964.3 3144267 3145019 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type t: transporter; manganese transport system ATP-binding protein MntB complement(3144267..3145019) Bacillus subtilis subsp. subtilis str. 168 937196 NP_390955.1 CDS mntA NC_000964.3 3145038 3145958 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type lp: lipoprotein; manganese-binding lipoprotein MntA complement(3145038..3145958) Bacillus subtilis subsp. subtilis str. 168 937219 NP_390956.1 CDS menC NC_000964.3 3146238 3147353 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 6780514, 8566759, 9139683; Product type e: enzyme; o-succinylbenzoate synthase complement(3146238..3147353) Bacillus subtilis subsp. subtilis str. 168 937201 NP_390957.1 CDS menE NC_000964.3 3147350 3148810 R converts O-succinylbenzoate to O-succinylbenzoyl-CoA; 2-succinylbenzoate--CoA ligase complement(3147350..3148810) Bacillus subtilis subsp. subtilis str. 168 937132 NP_390958.1 CDS menB NC_000964.3 3148901 3149716 R catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; 1,4-dihydroxy-2-naphthoyl-CoA synthase complement(3148901..3149716) Bacillus subtilis subsp. subtilis str. 168 937195 NP_390959.1 CDS ytxM NC_000964.3 3149751 3150575 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12454479; Product type pe : enzyme; esterase complement(3149751..3150575) Bacillus subtilis subsp. subtilis str. 168 937115 NP_390960.1 CDS menD NC_000964.3 3150563 3152305 R SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase complement(3150563..3152305) Bacillus subtilis subsp. subtilis str. 168 937198 NP_390961.1 CDS menF NC_000964.3 3152302 3153717 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 6780514, 8169214, 8566759; Product type e: enzyme; menaquinone-specific isochorismate synthase complement(3152302..3153717) Bacillus subtilis subsp. subtilis str. 168 937190 NP_390962.2 CDS yteA NC_000964.3 3154007 3154726 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987; hypothetical protein 3154007..3154726 Bacillus subtilis subsp. subtilis str. 168 937192 NP_390963.1 CDS ytdA NC_000964.3 3154735 3155553 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UTP--glucose-1-phosphate uridylyltransferase complement(3154735..3155553) Bacillus subtilis subsp. subtilis str. 168 937119 NP_390964.1 CDS ytcA NC_000964.3 3155725 3157011 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucose 6-dehydrogenase YtcA 3155725..3157011 Bacillus subtilis subsp. subtilis str. 168 936155 NP_390965.1 CDS ytcB NC_000964.3 3157008 3157958 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucose epimerase YtcB 3157008..3157958 Bacillus subtilis subsp. subtilis str. 168 938900 NP_390966.1 CDS ytcC NC_000964.3 3157961 3159184 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YtcC 3157961..3159184 Bacillus subtilis subsp. subtilis str. 168 939212 NP_390967.1 CDS ytxO NC_000964.3 3159258 3159689 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3159258..3159689) Bacillus subtilis subsp. subtilis str. 168 936317 NP_390968.1 CDS cotS NC_000964.3 3159691 3160746 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 7545510, 9603889; Product type cp: cell process; spore coat protein S complement(3159691..3160746) Bacillus subtilis subsp. subtilis str. 168 936628 NP_390969.1 CDS cotSA NC_000964.3 3160761 3161894 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 9603889; Product type cp: cell process; spore coat protein SA complement(3160761..3161894) Bacillus subtilis subsp. subtilis str. 168 936379 NP_390970.1 CDS cotI NC_000964.3 3162084 3163157 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor; spore coat protein I 3162084..3163157 Bacillus subtilis subsp. subtilis str. 168 936682 NP_390971.1 CDS ytaB NC_000964.3 3163237 3163704 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type prc: receptor; membrane protein 3163237..3163704 Bacillus subtilis subsp. subtilis str. 168 938164 NP_390972.1 CDS glgP NC_000964.3 3163735 3166131 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15272305, 8145641; Product type e: enzyme; glycogen phosphorylase complement(3163735..3166131) Bacillus subtilis subsp. subtilis str. 168 936630 NP_390973.1 CDS glgA NC_000964.3 3166118 3167572 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(3166118..3167572) Bacillus subtilis subsp. subtilis str. 168 936781 NP_390974.1 CDS glgD NC_000964.3 3167569 3168600 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8145641, 9244254; Product type e: enzyme; glycogen biosynthesis protein GlgD complement(3167569..3168600) Bacillus subtilis subsp. subtilis str. 168 936778 NP_390975.1 CDS glgC NC_000964.3 3168624 3169766 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(3168624..3169766) Bacillus subtilis subsp. subtilis str. 168 937990 NP_390976.1 CDS glgB NC_000964.3 3169763 3171646 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; 1,4-alpha-glucan branching enzyme GlgB complement(3169763..3171646) Bacillus subtilis subsp. subtilis str. 168 937993 NP_390977.1 CDS thiT NC_000964.3 3179306 3179884 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; thiamine transporter ThiT 3179306..3179884 Bacillus subtilis subsp. subtilis str. 168 937137 NP_390978.1 CDS yuaI NC_000964.3 3179926 3180447 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YuaI complement(3179926..3180447) Bacillus subtilis subsp. subtilis str. 168 938830 NP_390979.1 CDS yuaG NC_000964.3 3180465 3181994 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 17482313, 9153235, 9987136; Product type pf: factor; hypothetical protein complement(3180465..3181994) Bacillus subtilis subsp. subtilis str. 168 937138 NP_390980.1 CDS yuaF NC_000964.3 3182015 3182539 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 15849754, 16850406, 18696230; Product type pm: membrane component; membrane protein complement(3182015..3182539) Bacillus subtilis subsp. subtilis str. 168 937144 NP_390981.1 CDS yuaE NC_000964.3 3182707 3183195 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3182707..3183195 Bacillus subtilis subsp. subtilis str. 168 937143 NP_390982.1 CDS yuaD NC_000964.3 3183201 3183779 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11886751; metal-sulfur cluster biosynthesis proteins YuaD complement(3183201..3183779) Bacillus subtilis subsp. subtilis str. 168 937141 NP_390983.2 CDS gbsB NC_000964.3 3183867 3185075 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8752328; Product type e: enzyme; alcohol dehydrogenase complement(3183867..3185075) Bacillus subtilis subsp. subtilis str. 168 938832 NP_390984.1 CDS gbsA NC_000964.3 3185092 3186564 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8752328, 9297465; Product type e: enzyme; betaine aldehyde dehydrogenase complement(3185092..3186564) Bacillus subtilis subsp. subtilis str. 168 938829 NP_390985.1 CDS yuaC NC_000964.3 3186763 3187305 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8752328; Product type pr : regulator; hypothetical protein 3186763..3187305 Bacillus subtilis subsp. subtilis str. 168 938843 NP_390986.1 CDS yuaB NC_000964.3 3187503 3188048 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3187503..3188048 Bacillus subtilis subsp. subtilis str. 168 938831 NP_390987.1 CDS ktrA NC_000964.3 3188414 3189082 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter; ktr system potassium uptake protein A 3188414..3189082 Bacillus subtilis subsp. subtilis str. 168 937145 NP_390988.1 CDS ktrB NC_000964.3 3189089 3190426 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406, 17932047; Product type t : transporter; ktr system potassium uptake protein B 3189089..3190426 Bacillus subtilis subsp. subtilis str. 168 938835 NP_390989.1 CDS yubF NC_000964.3 3190462 3190725 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(3190462..3190725) Bacillus subtilis subsp. subtilis str. 168 937150 NP_390990.1 CDS lytG NC_000964.3 3190834 3191682 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12525152, 16855244; Product type e: enzyme; exo-glucosaminidase LytG complement(3190834..3191682) Bacillus subtilis subsp. subtilis str. 168 937146 NP_390991.1 CDS yubD NC_000964.3 3191843 3193378 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(3191843..3193378) Bacillus subtilis subsp. subtilis str. 168 938834 NP_390992.1 CDS cdoA NC_000964.3 3193863 3194348 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 15699190, 16855246; Product type e: enzyme; cysteine dioxygenase 3193863..3194348 Bacillus subtilis subsp. subtilis str. 168 938837 NP_390993.1 CDS yubB NC_000964.3 3194635 3195465 R BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl-diphosphatase complement(3194635..3195465) Bacillus subtilis subsp. subtilis str. 168 937148 NP_390994.1 CDS yubA NC_000964.3 3195558 3196724 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3195558..3196724) Bacillus subtilis subsp. subtilis str. 168 938833 NP_390995.1 CDS yulF NC_000964.3 3196906 3197892 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12450853; Product type ph: phenotype; oxidoreductase 3196906..3197892 Bacillus subtilis subsp. subtilis str. 168 937153 NP_390996.1 CDS yulE NC_000964.3 3197933 3199207 R catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase complement(3197933..3199207) Bacillus subtilis subsp. subtilis str. 168 938836 NP_390997.1 CDS yulD NC_000964.3 3199233 3199547 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15876375; Product type e: enzyme; L-rhamnose mutarotase complement(3199233..3199547) Bacillus subtilis subsp. subtilis str. 168 937151 NP_390998.1 CDS yulC NC_000964.3 3199565 3201022 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16674975; Product type e: enzyme; rhamnulokinase complement(3199565..3201022) Bacillus subtilis subsp. subtilis str. 168 938839 NP_390999.1 CDS yulB NC_000964.3 3201027 3201803 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11496004; Product type pr : regulator; DeoR family transcriptional regulator complement(3201027..3201803) Bacillus subtilis subsp. subtilis str. 168 938838 NP_391000.1 CDS yuxG NC_000964.3 3201860 3203929 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(3201860..3203929) Bacillus subtilis subsp. subtilis str. 168 938841 NP_391001.1 CDS tlpB NC_000964.3 3204067 3206055 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor; methyl-accepting chemotaxis protein TlpB complement(3204067..3206055) Bacillus subtilis subsp. subtilis str. 168 937152 NP_391002.2 CDS mcpA NC_000964.3 3206169 3208154 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 8188684, 9721285; Product type rc : receptor; methyl-accepting chemotaxis protein McpA complement(3206169..3208154) Bacillus subtilis subsp. subtilis str. 168 937154 NP_391003.1 CDS tlpA NC_000964.3 3208280 3210268 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor; methyl-accepting chemotaxis protein TlpA complement(3208280..3210268) Bacillus subtilis subsp. subtilis str. 168 938840 NP_391004.2 CDS mcpB NC_000964.3 3210445 3212433 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 14731274, 15317802, 15544802; Product type rc: receptor; methyl-accepting chemotaxis protein McpB complement(3210445..3212433) Bacillus subtilis subsp. subtilis str. 168 937155 NP_391005.1 CDS tgl NC_000964.3 3212591 3213328 D involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links; protein-glutamine gamma-glutamyltransferase 3212591..3213328 Bacillus subtilis subsp. subtilis str. 168 937158 YP_003097776.1 CDS yuzH NC_000964.3 3213342 3213596 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3213342..3213596) Bacillus subtilis subsp. subtilis str. 168 8303174 NP_391006.2 CDS yugU NC_000964.3 3213854 3214252 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3213854..3214252) Bacillus subtilis subsp. subtilis str. 168 937156 NP_391007.2 CDS yugT NC_000964.3 3214372 3216036 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1761534; Product type pe : enzyme; oligo-1,6-glucosidase 3 complement(3214372..3216036) Bacillus subtilis subsp. subtilis str. 168 938857 NP_391008.2 CDS yugS NC_000964.3 3216163 3217452 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; hypothetical protein complement(3216163..3217452) Bacillus subtilis subsp. subtilis str. 168 937160 NP_391009.1 CDS yugP NC_000964.3 3217496 3218173 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16704729, 16850406; Product type pe: enzyme; membrane protease YugP complement(3217496..3218173) Bacillus subtilis subsp. subtilis str. 168 938850 YP_003097777.1 CDS yuzI NC_000964.3 3218215 3218478 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16704729; Product type f : factor; membrane protein complement(3218215..3218478) Bacillus subtilis subsp. subtilis str. 168 8303062 YP_003097778.1 CDS mstX NC_000964.3 3218525 3218857 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15731457; Product type m: membrane component; protein mistic 3218525..3218857 Bacillus subtilis subsp. subtilis str. 168 8303011 NP_391010.3 CDS yugO NC_000964.3 3218854 3219840 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16704729; Product type pt : transporter; potassium channel protein YugO 3218854..3219840 Bacillus subtilis subsp. subtilis str. 168 938842 NP_391011.1 CDS yugN NC_000964.3 3219837 3220241 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3219837..3220241) Bacillus subtilis subsp. subtilis str. 168 938845 NP_391012.1 CDS yugM NC_000964.3 3220301 3220672 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(3220301..3220672) Bacillus subtilis subsp. subtilis str. 168 937159 NP_391013.2 CDS pgi NC_000964.3 3220731 3222083 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(3220731..3222083) Bacillus subtilis subsp. subtilis str. 168 937165 NP_391014.1 CDS yugK NC_000964.3 3222195 3223367 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADH-dependent butanol dehydrogenase 2 complement(3222195..3223367) Bacillus subtilis subsp. subtilis str. 168 938844 NP_391015.1 CDS yugJ NC_000964.3 3223471 3224634 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317791, 9643546; Product type pe: enzyme; NADH-dependent butanol dehydrogenase 1 complement(3223471..3224634) Bacillus subtilis subsp. subtilis str. 168 937164 NP_391016.1 CDS yuzA NC_000964.3 3224864 3225100 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3224864..3225100 Bacillus subtilis subsp. subtilis str. 168 937163 NP_391017.1 CDS yugI NC_000964.3 3225178 3225570 R induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation; general stress protein 13 complement(3225178..3225570) Bacillus subtilis subsp. subtilis str. 168 938849 NP_391018.2 CDS alaT NC_000964.3 3225772 3226932 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12670965; Product type pe : enzyme; aminotransferase YugH complement(3225772..3226932) Bacillus subtilis subsp. subtilis str. 168 938846 NP_391019.1 CDS yugG NC_000964.3 3226933 3227433 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AsnC family transcriptional regulator complement(3226933..3227433) Bacillus subtilis subsp. subtilis str. 168 937166 NP_391020.1 CDS yugF NC_000964.3 3227581 3228402 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase 3227581..3228402 Bacillus subtilis subsp. subtilis str. 168 937169 NP_391021.2 CDS yugE NC_000964.3 3228431 3228691 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3228431..3228691) Bacillus subtilis subsp. subtilis str. 168 938847 NP_391022.1 CDS patB NC_000964.3 3228778 3229941 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15760717; Product type e: enzyme; cystathionine beta-lyase 3228778..3229941 Bacillus subtilis subsp. subtilis str. 168 937170 NP_391023.2 CDS kinB NC_000964.3 3230067 3231353 D Evidence 2b: Function of strongly homologous gene; PubMedId: 11069677, 15849754, 16850406, 9426145; Product type e: enzyme; sporulation kinase B 3230067..3231353 Bacillus subtilis subsp. subtilis str. 168 937167 NP_391024.1 CDS kapB NC_000964.3 3231399 3231785 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9426145; Product type f : factor; kinase-associated lipoprotein B 3231399..3231785 Bacillus subtilis subsp. subtilis str. 168 938848 NP_391025.1 CDS kapD NC_000964.3 3231812 3232429 R inhibitor of the KinA pathway of sporulation; 3'-5' exonuclease KapD complement(3231812..3232429) Bacillus subtilis subsp. subtilis str. 168 937171 NP_391026.2 CDS yuxJ NC_000964.3 3232640 3233818 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3232640..3233818 Bacillus subtilis subsp. subtilis str. 168 938852 NP_391027.2 CDS pbpD NC_000964.3 3233911 3235785 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7961491, 9274030; Product type e: enzyme; penicillin-binding protein 4 3233911..3235785 Bacillus subtilis subsp. subtilis str. 168 938851 NP_391028.1 CDS yuxK NC_000964.3 3235806 3236219 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3235806..3236219 Bacillus subtilis subsp. subtilis str. 168 938854 NP_391029.2 CDS yufK NC_000964.3 3236422 3236979 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3236422..3236979) Bacillus subtilis subsp. subtilis str. 168 938853 NP_391030.1 CDS yufL NC_000964.3 3237157 3238758 D C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensor histidine kinase 3237157..3238758 Bacillus subtilis subsp. subtilis str. 168 937173 NP_391031.1 CDS yufM NC_000964.3 3238751 3239458 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12949159; Product type r: regulator; transcriptional regulatory protein MalR 3238751..3239458 Bacillus subtilis subsp. subtilis str. 168 937174 NP_391032.2 CDS yufN NC_000964.3 3239930 3241009 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3239930..3241009 Bacillus subtilis subsp. subtilis str. 168 938870 NP_391033.1 CDS yufO NC_000964.3 3241085 3242617 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3241085..3242617 Bacillus subtilis subsp. subtilis str. 168 937172 NP_391034.1 CDS yufP NC_000964.3 3242610 3243656 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3242610..3243656 Bacillus subtilis subsp. subtilis str. 168 937175 NP_391035.1 CDS yufQ NC_000964.3 3243657 3244616 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3243657..3244616 Bacillus subtilis subsp. subtilis str. 168 937176 NP_391036.1 CDS maeN NC_000964.3 3244770 3246116 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11004162, 12949159, 15849754, 16850406; Product type t: transporter; Na(+)-malate symporter 3244770..3246116 Bacillus subtilis subsp. subtilis str. 168 938855 NP_391037.1 CDS yufS NC_000964.3 3246152 3246367 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; hypothetical protein complement(3246152..3246367) Bacillus subtilis subsp. subtilis str. 168 938856 NP_391038.2 CDS mrpA NC_000964.3 3246598 3249003 D subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit A 3246598..3249003 Bacillus subtilis subsp. subtilis str. 168 938828 NP_391039.1 CDS mrpB NC_000964.3 3248996 3249427 D subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport; Na(+)/H(+) antiporter subunit B 3248996..3249427 Bacillus subtilis subsp. subtilis str. 168 937177 NP_391040.2 CDS mrpC NC_000964.3 3249427 3249768 D subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit C 3249427..3249768 Bacillus subtilis subsp. subtilis str. 168 937139 NP_391041.3 CDS mrpD NC_000964.3 3249761 3251242 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; Na(+)/H(+) antiporter subunit D 3249761..3251242 Bacillus subtilis subsp. subtilis str. 168 938858 YP_054591.2 CDS mrpE NC_000964.3 3251248 3251724 D subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit E 3251248..3251724 Bacillus subtilis subsp. subtilis str. 168 2914191 NP_391043.2 CDS mrpF NC_000964.3 3251724 3252008 D subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit F 3251724..3252008 Bacillus subtilis subsp. subtilis str. 168 938862 NP_391044.1 CDS mrpG NC_000964.3 3251992 3252366 D subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Na(+)/H(+) antiporter subunit G 3251992..3252366 Bacillus subtilis subsp. subtilis str. 168 938864 NP_391045.2 CDS yuxO NC_000964.3 3252405 3252785 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; esterase ComA2 complement(3252405..3252785) Bacillus subtilis subsp. subtilis str. 168 937178 NP_391046.1 CDS comA NC_000964.3 3252804 3253448 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972833, 11179649, 11717295, 12950917, 16816200; Product type r: regulator; transcriptional regulatory protein ComA complement(3252804..3253448) Bacillus subtilis subsp. subtilis str. 168 937179 NP_391047.2 CDS comP NC_000964.3 3253529 3255838 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10419951, 14679219, 15066026, 16091050, 16787201, 7698645, 7855425; Product type rc: receptor; sensor histidine kinase complement(3253529..3255838) Bacillus subtilis subsp. subtilis str. 168 938866 NP_391048.1 CDS comX NC_000964.3 3255853 3256020 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141, 18323630; Product type f : factor; competence pheromone complement(3255853..3256020) Bacillus subtilis subsp. subtilis str. 168 938875 NP_391049.2 CDS comQ NC_000964.3 3256008 3256907 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141; Product type e: enzyme; competence regulatory protein ComQ complement(3256008..3256907) Bacillus subtilis subsp. subtilis str. 168 937180 NP_391050.1 CDS degQ NC_000964.3 3257092 3257232 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16251307, 16942812, 1901055; Product type r: regulator; degradation enzyme regulation protein DegQ complement(3257092..3257232) Bacillus subtilis subsp. subtilis str. 168 936547 NP_391051.2 CDS yuzC NC_000964.3 3257693 3258061 D Evidence 2b: Function of strongly homologous gene; PubMedId: 16321932; Product type cp: cell process; hypothetical protein 3257693..3258061 Bacillus subtilis subsp. subtilis str. 168 938859 NP_391052.1 CDS pdeH NC_000964.3 3258037 3259266 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17153922; Product type pe : enzyme; phosphodiesterase complement(3258037..3259266) Bacillus subtilis subsp. subtilis str. 168 937185 NP_391053.1 CDS yueK NC_000964.3 3259403 3260875 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(3259403..3260875) Bacillus subtilis subsp. subtilis str. 168 937186 NP_391054.1 CDS pncA NC_000964.3 3260891 3261442 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15135535, 17382284; Product type e: enzyme; isochorismatase complement(3260891..3261442) Bacillus subtilis subsp. subtilis str. 168 938863 NP_391055.1 CDS yueI NC_000964.3 3261539 3261937 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3261539..3261937) Bacillus subtilis subsp. subtilis str. 168 938125 NP_391056.1 CDS yueH NC_000964.3 3262009 3262257 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3262009..3262257) Bacillus subtilis subsp. subtilis str. 168 936537 NP_391057.1 CDS yueG NC_000964.3 3262330 3262551 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; spore germination protein-like protein YueG complement(3262330..3262551) Bacillus subtilis subsp. subtilis str. 168 936561 NP_391058.1 CDS yueF NC_000964.3 3262611 3263720 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3262611..3263720) Bacillus subtilis subsp. subtilis str. 168 936534 NP_391059.1 CDS yuzE NC_000964.3 3263835 3264224 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3263835..3264224 Bacillus subtilis subsp. subtilis str. 168 937187 NP_391060.1 CDS yuzF NC_000964.3 3264265 3264501 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3264265..3264501) Bacillus subtilis subsp. subtilis str. 168 936562 NP_391061.1 CDS yueE NC_000964.3 3264678 3265208 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphohydrolase YueE complement(3264678..3265208) Bacillus subtilis subsp. subtilis str. 168 936545 NP_391062.1 CDS yueD NC_000964.3 3265406 3266137 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11745140; Product type pe : enzyme; benzil reductase complement(3265406..3266137) Bacillus subtilis subsp. subtilis str. 168 936558 NP_391063.1 CDS yueC NC_000964.3 3266200 3266655 R Evidence 5: No homology to any previously reported sequences; PubMedId: 15576783; hypothetical protein complement(3266200..3266655) Bacillus subtilis subsp. subtilis str. 168 936550 NP_391064.1 CDS yueB NC_000964.3 3266687 3269917 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576783; Product type ph: phenotype; bacteriophage SPP1 adsorption protein YueB complement(3266687..3269917) Bacillus subtilis subsp. subtilis str. 168 936567 NP_391066.2 CDS yukB NC_000964.3 3269914 3274401 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor; Ftsk domain-containing protein YukB complement(3269914..3274401) Bacillus subtilis subsp. subtilis str. 168 936565 NP_391067.1 CDS yukC NC_000964.3 3274462 3275817 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pe: enzyme; hypothetical protein complement(3274462..3275817) Bacillus subtilis subsp. subtilis str. 168 936572 NP_391068.1 CDS yukD NC_000964.3 3275832 3276071 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pf: factor; ubiquitin-like protein YukD complement(3275832..3276071) Bacillus subtilis subsp. subtilis str. 168 936543 NP_391069.2 CDS yukE NC_000964.3 3276141 3276434 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783; hypothetical protein complement(3276141..3276434) Bacillus subtilis subsp. subtilis str. 168 936578 NP_391070.2 CDS yukF NC_000964.3 3276955 3278223 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator 3276955..3278223 Bacillus subtilis subsp. subtilis str. 168 938860 NP_391071.1 CDS ald NC_000964.3 3278325 3279461 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226620; Product type e : enzyme; alanine dehydrogenase 3278325..3279461 Bacillus subtilis subsp. subtilis str. 168 936557 NP_391073.2 CDS yukJ NC_000964.3 3279573 3280250 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3279573..3280250 Bacillus subtilis subsp. subtilis str. 168 937111 YP_003097779.1 CDS ybdZ NC_000964.3 3280294 3280503 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11112781; hypothetical protein complement(3280294..3280503) Bacillus subtilis subsp. subtilis str. 168 8303138 NP_391076.3 CDS dhbF NC_000964.3 3280519 3287655 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11112781, 12354229, 16672620; Product type e: enzyme; dimodular nonribosomal peptide synthase complement(3280519..3287655) Bacillus subtilis subsp. subtilis str. 168 936569 NP_391077.1 CDS dhbB NC_000964.3 3287675 3288613 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme; isochorismatase complement(3287675..3288613) Bacillus subtilis subsp. subtilis str. 168 936582 NP_391078.1 CDS dhbE NC_000964.3 3288641 3290260 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme; 2,3-dihydroxybenzoate-AMP ligase complement(3288641..3290260) Bacillus subtilis subsp. subtilis str. 168 936509 NP_391079.2 CDS dhbC NC_000964.3 3290289 3291485 R synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis; isochorismate synthase DhbC complement(3290289..3291485) Bacillus subtilis subsp. subtilis str. 168 937162 NP_391080.2 CDS dhbA NC_000964.3 3291511 3292296 R catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase complement(3291511..3292296) Bacillus subtilis subsp. subtilis str. 168 936579 NP_391081.2 CDS besA NC_000964.3 3292490 3293359 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16889643; Product type e: enzyme; ferri-bacillibactin esterase BesA complement(3292490..3293359) Bacillus subtilis subsp. subtilis str. 168 936592 NP_391082.1 CDS yuiH NC_000964.3 3293573 3294169 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11598126, 16341843; Product type pe: enzyme; oxidoreductase complement(3293573..3294169) Bacillus subtilis subsp. subtilis str. 168 937188 NP_391083.1 CDS bioYB NC_000964.3 3294270 3294872 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11717296, 15849754, 16850406; Product type pt: transporter; biotin transporter BioYB 3294270..3294872 Bacillus subtilis subsp. subtilis str. 168 936511 NP_391084.1 CDS yuiF NC_000964.3 3294942 3296270 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15135544, 15849754, 16850406; Product type t: transporter; amino acid transporter YuiF complement(3294942..3296270) Bacillus subtilis subsp. subtilis str. 168 937212 NP_391085.1 CDS yuiE NC_000964.3 3296417 3297919 R catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; cytosol aminopeptidase complement(3296417..3297919) Bacillus subtilis subsp. subtilis str. 168 936587 NP_391086.1 CDS yuiD NC_000964.3 3298077 3298553 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3298077..3298553 Bacillus subtilis subsp. subtilis str. 168 936516 NP_391087.1 CDS yuiC NC_000964.3 3298584 3299240 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3298584..3299240) Bacillus subtilis subsp. subtilis str. 168 936601 NP_391088.1 CDS yuiB NC_000964.3 3299344 3299664 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(3299344..3299664) Bacillus subtilis subsp. subtilis str. 168 938035 NP_391089.1 CDS yuiA NC_000964.3 3299718 3299861 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3299718..3299861) Bacillus subtilis subsp. subtilis str. 168 938869 NP_391090.1 CDS yumB NC_000964.3 3300034 3301254 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154, 17015645; Product type pe: enzyme; NADH dehydrogenase-like protein YumB complement(3300034..3301254) Bacillus subtilis subsp. subtilis str. 168 937062 NP_391091.2 CDS yumC NC_000964.3 3301586 3302584 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme; ferredoxin--NADP reductase 2 3301586..3302584 Bacillus subtilis subsp. subtilis str. 168 936577 NP_391092.1 CDS yuzG NC_000964.3 3302623 3302763 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3302623..3302763) Bacillus subtilis subsp. subtilis str. 168 936597 NP_391093.2 CDS guaC NC_000964.3 3303042 3304022 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11591660, 6408059; Product type e: enzyme; GMP reductase 3303042..3304022 Bacillus subtilis subsp. subtilis str. 168 937189 NP_391094.2 CDS paiB NC_000964.3 3304096 3304719 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16210326; Product type pe : enzyme; protease synthase and sporulation protein PAI 2 complement(3304096..3304719) Bacillus subtilis subsp. subtilis str. 168 936588 NP_391095.1 CDS paiA NC_000964.3 3304743 3305261 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16210326, 17588214; Product type e: enzyme; protease synthase and sporulation negative regulatory protein PAI 1 complement(3304743..3305261) Bacillus subtilis subsp. subtilis str. 168 937204 NP_391096.1 CDS yutM NC_000964.3 3305599 3305961 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(3305599..3305961) Bacillus subtilis subsp. subtilis str. 168 936627 NP_391097.1 CDS dapF NC_000964.3 3306040 3306894 R involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase complement(3306040..3306894) Bacillus subtilis subsp. subtilis str. 168 937110 NP_391098.1 CDS yutK NC_000964.3 3307017 3308231 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(3307017..3308231) Bacillus subtilis subsp. subtilis str. 168 936517 NP_391099.1 CDS yuzB NC_000964.3 3308368 3308604 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3308368..3308604) Bacillus subtilis subsp. subtilis str. 168 936585 NP_391100.2 CDS yutJ NC_000964.3 3308867 3309934 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17015645; Product type pe : enzyme; NADH dehydrogenase-like protein YutJ 3308867..3309934 Bacillus subtilis subsp. subtilis str. 168 936600 NP_391101.1 CDS yuzD NC_000964.3 3309960 3310286 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11551182; Product type pe : enzyme; disulfide oxidoreductase YuzD complement(3309960..3310286) Bacillus subtilis subsp. subtilis str. 168 937202 NP_391102.1 CDS yutI NC_000964.3 3310386 3310721 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17237162; Product type pf : factor; nitrogen fixation protein YutI 3310386..3310721 Bacillus subtilis subsp. subtilis str. 168 936658 NP_391103.2 CDS yuxL NC_000964.3 3310763 3312736 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8576092; Product type pe : enzyme; peptidase YuxL complement(3310763..3312736) Bacillus subtilis subsp. subtilis str. 168 936648 NP_391104.1 CDS thrB NC_000964.3 3312844 3313773 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(3312844..3313773) Bacillus subtilis subsp. subtilis str. 168 936665 NP_391105.1 CDS thrC NC_000964.3 3313770 3314828 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(3313770..3314828) Bacillus subtilis subsp. subtilis str. 168 936660 NP_391106.1 CDS hom NC_000964.3 3314828 3316129 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(3314828..3316129) Bacillus subtilis subsp. subtilis str. 168 936654 NP_391107.1 CDS yutH NC_000964.3 3316330 3317349 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type cp: cell process; endospore coat-associated protein YutH complement(3316330..3317349) Bacillus subtilis subsp. subtilis str. 168 936635 NP_391108.1 CDS yutG NC_000964.3 3317502 3318002 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3317502..3318002 Bacillus subtilis subsp. subtilis str. 168 936659 NP_391109.1 CDS yutF NC_000964.3 3318029 3318799 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15664928, 16766528; Product type pe: enzyme; hydrolase YutF complement(3318029..3318799) Bacillus subtilis subsp. subtilis str. 168 936508 NP_391110.1 CDS yutE NC_000964.3 3318828 3319262 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3318828..3319262) Bacillus subtilis subsp. subtilis str. 168 938483 NP_391111.2 CDS yutD NC_000964.3 3319286 3319561 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717; hypothetical protein complement(3319286..3319561) Bacillus subtilis subsp. subtilis str. 168 937182 NP_391112.1 CDS yutC NC_000964.3 3319676 3320308 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3319676..3320308 Bacillus subtilis subsp. subtilis str. 168 936674 NP_391113.2 CDS lipA NC_000964.3 3320324 3321220 R catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(3320324..3321220) Bacillus subtilis subsp. subtilis str. 168 938861 NP_391114.2 CDS lytH NC_000964.3 3321455 3322435 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12813075; Product type cp: cell process; L-Ala--D-Glu endopeptidase 3321455..3322435 Bacillus subtilis subsp. subtilis str. 168 936510 NP_391115.1 CDS yunB NC_000964.3 3322463 3323227 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922; Product type cp : cell process; sporulation protein YunB complement(3322463..3323227) Bacillus subtilis subsp. subtilis str. 168 936670 NP_391116.1 CDS yunC NC_000964.3 3323300 3323605 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(3323300..3323605) Bacillus subtilis subsp. subtilis str. 168 936679 NP_391117.1 CDS yunD NC_000964.3 3323670 3325058 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase complement(3323670..3325058) Bacillus subtilis subsp. subtilis str. 168 936666 NP_391118.1 CDS yunE NC_000964.3 3325078 3325899 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3325078..3325899) Bacillus subtilis subsp. subtilis str. 168 936506 NP_391119.2 CDS yunF NC_000964.3 3325917 3326765 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3325917..3326765) Bacillus subtilis subsp. subtilis str. 168 937089 NP_391120.1 CDS yunG NC_000964.3 3326803 3327150 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3326803..3327150) Bacillus subtilis subsp. subtilis str. 168 936684 NP_391121.1 CDS pucH NC_000964.3 3327247 3328587 R Plays a crucial role on both purine and pyrimidine metabolism; allantoinase complement(3327247..3328587) Bacillus subtilis subsp. subtilis str. 168 936662 NP_391122.1 CDS pucR NC_000964.3 3328762 3330357 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 12374841; Product type r: regulator; purine catabolism regulatory protein 3328762..3330357 Bacillus subtilis subsp. subtilis str. 168 937221 NP_391123.1 CDS pucJ NC_000964.3 3330502 3331851 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter; uric acid permease PucJ 3330502..3331851 Bacillus subtilis subsp. subtilis str. 168 937096 NP_391124.1 CDS pucK NC_000964.3 3331857 3333149 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter; uric acid permease PucK 3331857..3333149 Bacillus subtilis subsp. subtilis str. 168 937191 NP_391125.1 CDS pucL NC_000964.3 3333162 3334646 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; urate oxidase with peroxide reductase N-terminal domain 3333162..3334646 Bacillus subtilis subsp. subtilis str. 168 936669 NP_391126.2 CDS pucM NC_000964.3 3334646 3334990 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11344136; Product type s: structure; 5-hydroxyisourate hydrolase 3334646..3334990 Bacillus subtilis subsp. subtilis str. 168 937977 YP_003097780.1 CDS yuzJ NC_000964.3 3335414 3335545 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3335414..3335545 Bacillus subtilis subsp. subtilis str. 168 8303056 NP_391127.1 CDS pucE NC_000964.3 3335751 3336272 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit E complement(3335751..3336272) Bacillus subtilis subsp. subtilis str. 168 936680 NP_391128.1 CDS pucD NC_000964.3 3336263 3338500 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit D complement(3336263..3338500) Bacillus subtilis subsp. subtilis str. 168 936686 NP_391129.1 CDS pucC NC_000964.3 3338501 3339334 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit C complement(3338501..3339334) Bacillus subtilis subsp. subtilis str. 168 936685 NP_391130.2 CDS pucB NC_000964.3 3339331 3339948 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; purine catabolism protein PucB complement(3339331..3339948) Bacillus subtilis subsp. subtilis str. 168 936486 NP_391131.1 CDS pucA NC_000964.3 3339945 3340937 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type c: carrier; xanthine dehydrogenase subunit A complement(3339945..3340937) Bacillus subtilis subsp. subtilis str. 168 938865 NP_391132.1 CDS pucG NC_000964.3 3341166 3342416 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11344136; Product type pe : enzyme; purine catabolism protein PucG complement(3341166..3342416) Bacillus subtilis subsp. subtilis str. 168 936676 NP_391133.1 CDS yurH NC_000964.3 3342433 3343671 R allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase complement(3342433..3343671) Bacillus subtilis subsp. subtilis str. 168 936699 NP_391134.1 CDS bsn NC_000964.3 3344113 3344979 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12490701, 16291680; Product type e: enzyme; extracellular ribonuclease 3344113..3344979 Bacillus subtilis subsp. subtilis str. 168 936687 NP_391135.1 CDS yurJ NC_000964.3 3345013 3346116 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein complement(3345013..3346116) Bacillus subtilis subsp. subtilis str. 168 937070 NP_391136.2 CDS frlR NC_000964.3 3346238 3347026 D may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3346238..3347026 Bacillus subtilis subsp. subtilis str. 168 936688 NP_391137.1 CDS frlD NC_000964.3 3347051 3347905 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14641112, 16153181; Product type e: enzyme; fructosamine kinase FrlD complement(3347051..3347905) Bacillus subtilis subsp. subtilis str. 168 936704 NP_391138.1 CDS frlM NC_000964.3 3347919 3348821 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter; ABC transporter permease complement(3347919..3348821) Bacillus subtilis subsp. subtilis str. 168 936696 NP_391139.1 CDS frlN NC_000964.3 3348825 3349703 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter; ABC transporter permease complement(3348825..3349703) Bacillus subtilis subsp. subtilis str. 168 936689 NP_391140.1 CDS frlO NC_000964.3 3349761 3351029 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455; Product type pt : transporter; ABC transporter extracellular-binding protein YurO complement(3349761..3351029) Bacillus subtilis subsp. subtilis str. 168 937094 NP_391141.1 CDS frlB NC_000964.3 3351110 3352096 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12618455, 16153181; Product type e: enzyme; fructosamine deglycase FrlB complement(3351110..3352096) Bacillus subtilis subsp. subtilis str. 168 936701 NP_391142.1 CDS yurQ NC_000964.3 3352312 3352686 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3352312..3352686) Bacillus subtilis subsp. subtilis str. 168 936694 NP_391143.1 CDS yurR NC_000964.3 3352789 3353907 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(3352789..3353907) Bacillus subtilis subsp. subtilis str. 168 937069 YP_054592.1 CDS sspG NC_000964.3 3354066 3354212 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type f : factor; small acid-soluble spore protein G 3354066..3354212 Bacillus subtilis subsp. subtilis str. 168 2914218 NP_391144.1 CDS yurS NC_000964.3 3354212 3354487 D Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018; hypothetical protein 3354212..3354487 Bacillus subtilis subsp. subtilis str. 168 936705 NP_391145.1 CDS yurT NC_000964.3 3354551 3354934 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10882093; Product type pe : enzyme; hypothetical protein complement(3354551..3354934) Bacillus subtilis subsp. subtilis str. 168 937193 YP_003097781.1 CDS yuzN NC_000964.3 3355045 3355323 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YuzN complement(3355045..3355323) Bacillus subtilis subsp. subtilis str. 168 8303129 NP_391146.1 CDS sufB NC_000964.3 3355593 3356990 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor; FeS cluster assembly protein SufB complement(3355593..3356990) Bacillus subtilis subsp. subtilis str. 168 936706 NP_391147.1 CDS iscU NC_000964.3 3357011 3357454 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16877383; Product type f : factor; NifU-like protein complement(3357011..3357454) Bacillus subtilis subsp. subtilis str. 168 936702 NP_391148.1 CDS sufS NC_000964.3 3357444 3358664 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 12876288, 14644425, 15901727; Product type e: enzyme; cysteine desulfurase complement(3357444..3358664) Bacillus subtilis subsp. subtilis str. 168 937108 NP_391149.1 CDS sufD NC_000964.3 3358664 3359977 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor; FeS cluster assembly protein SufD complement(3358664..3359977) Bacillus subtilis subsp. subtilis str. 168 938871 NP_391150.1 CDS sufC NC_000964.3 3359995 3360780 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16431905; Product type e : enzyme; vegetative protein 296 complement(3359995..3360780) Bacillus subtilis subsp. subtilis str. 168 937073 YP_003097782.1 CDS yuzK NC_000964.3 3360974 3361111 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3360974..3361111) Bacillus subtilis subsp. subtilis str. 168 8303161 NP_391151.1 CDS yurZ NC_000964.3 3361305 3361682 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3361305..3361682) Bacillus subtilis subsp. subtilis str. 168 937080 NP_391152.1 CDS metN NC_000964.3 3361767 3362591 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter; methionine-binding lipoprotein MetQ complement(3361767..3362591) Bacillus subtilis subsp. subtilis str. 168 936716 NP_391153.1 CDS metP NC_000964.3 3362605 3363273 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 15849754, 16850406, 17038623, 10094622; Product type t : transporter; methionine import system permease protein MetP complement(3362605..3363273) Bacillus subtilis subsp. subtilis str. 168 936709 NP_391154.1 CDS metQ NC_000964.3 3363266 3364291 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter; methionine import ATP-binding protein MetN complement(3363266..3364291) Bacillus subtilis subsp. subtilis str. 168 936700 NP_391155.1 CDS yusD NC_000964.3 3364618 3364962 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3364618..3364962) Bacillus subtilis subsp. subtilis str. 168 936713 NP_391156.1 CDS yusE NC_000964.3 3365069 3365389 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; thioredoxin complement(3365069..3365389) Bacillus subtilis subsp. subtilis str. 168 937184 NP_391157.1 CDS yusF NC_000964.3 3365391 3365831 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12794188; Product type pe : enzyme; hypothetical protein complement(3365391..3365831) Bacillus subtilis subsp. subtilis str. 168 936707 NP_391158.1 CDS yusG NC_000964.3 3365831 3366067 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3365831..3366067) Bacillus subtilis subsp. subtilis str. 168 936719 NP_391159.1 CDS yusH NC_000964.3 3366123 3366506 R part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system H protein complement(3366123..3366506) Bacillus subtilis subsp. subtilis str. 168 936724 NP_391160.1 CDS yusI NC_000964.3 3366573 3366929 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3366573..3366929) Bacillus subtilis subsp. subtilis str. 168 936722 NP_391161.1 CDS fadE NC_000964.3 3367040 3368824 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; acyl-CoA dehydrogenase complement(3367040..3368824) Bacillus subtilis subsp. subtilis str. 168 936717 NP_391162.1 CDS yusK NC_000964.3 3368839 3370014 R Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; 3-ketoacyl-CoA thiolase complement(3368839..3370014) Bacillus subtilis subsp. subtilis str. 168 936729 NP_391163.1 CDS fadN NC_000964.3 3370025 3372472 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; enoyl-CoA hydratase complement(3370025..3372472) Bacillus subtilis subsp. subtilis str. 168 937125 YP_003097783.1 CDS yuzL NC_000964.3 3372569 3372715 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250; hypothetical protein 3372569..3372715 Bacillus subtilis subsp. subtilis str. 168 8302982 NP_391164.1 CDS fadM NC_000964.3 3372740 3373648 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; proline dehydrogenase 1 complement(3372740..3373648) Bacillus subtilis subsp. subtilis str. 168 937064 YP_003097784.1 CDS yuzM NC_000964.3 3373743 3373988 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3373743..3373988 Bacillus subtilis subsp. subtilis str. 168 8302981 NP_391165.1 CDS yusN NC_000964.3 3374001 3374333 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3374001..3374333 Bacillus subtilis subsp. subtilis str. 168 937194 NP_391166.1 CDS yusO NC_000964.3 3374492 3374959 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12923086; Product type pr : regulator; HTH-type transcriptional regulator YusO 3374492..3374959 Bacillus subtilis subsp. subtilis str. 168 935923 NP_391167.1 CDS yusP NC_000964.3 3374956 3376581 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3374956..3376581 Bacillus subtilis subsp. subtilis str. 168 937088 NP_391168.1 CDS yusQ NC_000964.3 3376617 3377000 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YusQ complement(3376617..3377000) Bacillus subtilis subsp. subtilis str. 168 938468 NP_391169.1 CDS yusR NC_000964.3 3377019 3377408 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 3-oxoacyl-ACP reductase complement(3377019..3377408) Bacillus subtilis subsp. subtilis str. 168 937076 NP_391170.1 CDS yusS NC_000964.3 3377430 3377759 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; short-chain dehydrogenase/reductase homolog YusS complement(3377430..3377759) Bacillus subtilis subsp. subtilis str. 168 935924 NP_391171.1 CDS yusT NC_000964.3 3377893 3378780 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YusT 3377893..3378780 Bacillus subtilis subsp. subtilis str. 168 938601 NP_391172.1 CDS yusU NC_000964.3 3378800 3379087 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3378800..3379087) Bacillus subtilis subsp. subtilis str. 168 935925 NP_391173.1 CDS yusV NC_000964.3 3379112 3379939 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter; siderophore transport system ATP-binding protein YusV complement(3379112..3379939) Bacillus subtilis subsp. subtilis str. 168 935921 NP_391174.1 CDS yusW NC_000964.3 3380157 3380594 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein complement(3380157..3380594) Bacillus subtilis subsp. subtilis str. 168 938599 NP_391177.1 CDS yusZ NC_000964.3 3382633 3383475 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 3382633..3383475 Bacillus subtilis subsp. subtilis str. 168 938596 NP_391178.1 CDS mrgA NC_000964.3 3383565 3384026 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 8709848; Product type f: factor; metalloregulation DNA-binding stress protein 3383565..3384026 Bacillus subtilis subsp. subtilis str. 168 938592 NP_391180.2 CDS htrB NC_000964.3 3384070 3385446 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11133960, 11717295, 16033468, 16911528; Product type e: enzyme; serine protease Do-like HtrB complement(3384070..3385446) Bacillus subtilis subsp. subtilis str. 168 935935 NP_391181.1 CDS cssR NC_000964.3 3385724 3386401 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type r: regulator; transcriptional regulatory protein CssR 3385724..3386401 Bacillus subtilis subsp. subtilis str. 168 938594 NP_391182.2 CDS cssS NC_000964.3 3386398 3387753 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type rc: receptor; sensor histidine kinase 3386398..3387753 Bacillus subtilis subsp. subtilis str. 168 935936 YP_003097785.1 CDS yuzO NC_000964.3 3387781 3387945 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3387781..3387945) Bacillus subtilis subsp. subtilis str. 168 8303202 NP_391183.1 CDS yuxN NC_000964.3 3388113 3388988 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YuxN 3388113..3388988 Bacillus subtilis subsp. subtilis str. 168 935945 NP_391184.1 CDS fumC NC_000964.3 3389024 3390412 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase class II complement(3389024..3390412) Bacillus subtilis subsp. subtilis str. 168 938591 YP_003097786.1 CDS yvzF NC_000964.3 3390479 3390664 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3390479..3390664) Bacillus subtilis subsp. subtilis str. 168 8303152 NP_391185.2 CDS gerAA NC_000964.3 3390782 3392230 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process; spore germination protein A1 3390782..3392230 Bacillus subtilis subsp. subtilis str. 168 935953 NP_391186.1 CDS gerAB NC_000964.3 3392199 3393296 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16740944, 16850406; Product type cp: cell process; spore germination protein A2 3392199..3393296 Bacillus subtilis subsp. subtilis str. 168 935948 NP_391187.1 CDS gerAC NC_000964.3 3393293 3394414 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process; spore germination protein A3 3393293..3394414 Bacillus subtilis subsp. subtilis str. 168 935951 NP_391188.1 CDS liaR NC_000964.3 3394422 3395057 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type r: regulator; transcriptional regulatory protein LiaR complement(3394422..3395057) Bacillus subtilis subsp. subtilis str. 168 935957 NP_391189.1 CDS liaS NC_000964.3 3395035 3396117 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type rc: receptor; sensor histidine kinase complement(3395035..3396117) Bacillus subtilis subsp. subtilis str. 168 935967 NP_391190.1 CDS liaF NC_000964.3 3396114 3396839 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406, 17660417; Product type m: membrane component; LiaR negative effector LiaF complement(3396114..3396839) Bacillus subtilis subsp. subtilis str. 168 938469 NP_391191.2 CDS liaG NC_000964.3 3396873 3397745 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15273097, 16816187; protein LiaG complement(3396873..3397745) Bacillus subtilis subsp. subtilis str. 168 938471 NP_391192.1 CDS liaH NC_000964.3 3397846 3398523 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187; Product type f: factor; lia operon expression modulator LiaH complement(3397846..3398523) Bacillus subtilis subsp. subtilis str. 168 938585 NP_391193.1 CDS liaI NC_000964.3 3398550 3398930 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406; Product type t: transporter; protein LiaI complement(3398550..3398930) Bacillus subtilis subsp. subtilis str. 168 935958 NP_391194.1 CDS yvqJ NC_000964.3 3399092 3400360 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(3399092..3400360) Bacillus subtilis subsp. subtilis str. 168 935970 NP_391195.2 CDS yvqK NC_000964.3 3400537 3401118 R Evidence 2b: Function of strongly homologous gene; PubMedId: 14704351, 17588214; Product type e : enzyme; Cob(i)yrinic acid a,c-diamide adenosyltransferase complement(3400537..3401118) Bacillus subtilis subsp. subtilis str. 168 935972 NP_391196.1 CDS yvrA NC_000964.3 3401141 3402469 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type pt : transporter; ABC transporter ATP-binding protein complement(3401141..3402469) Bacillus subtilis subsp. subtilis str. 168 935968 NP_391197.1 CDS yvrB NC_000964.3 3402469 3403530 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351, 15849754, 16850406; Product type pt: transporter; ABC transporter permease complement(3402469..3403530) Bacillus subtilis subsp. subtilis str. 168 938583 NP_391198.1 CDS yvrC NC_000964.3 3403493 3404437 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type t : transporter; ABC transporter substrate-binding protein complement(3403493..3404437) Bacillus subtilis subsp. subtilis str. 168 935980 NP_391199.1 CDS yvrD NC_000964.3 3404835 3405626 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9922248; Product type pe : enzyme; oxidoreductase 3404835..3405626 Bacillus subtilis subsp. subtilis str. 168 938584 NP_391200.1 CDS yvrE NC_000964.3 3405664 3406542 R Evidence 4: Homologs of previously reported genes of unknown function; sugar lactone lactonase YvrE complement(3405664..3406542) Bacillus subtilis subsp. subtilis str. 168 935979 NP_391201.2 CDS yvrG NC_000964.3 3406614 3408356 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717295, 16306698; Product type rc : receptor; sensor histidine kinase complement(3406614..3408356) Bacillus subtilis subsp. subtilis str. 168 935985 NP_391202.2 CDS yvrH NC_000964.3 3408353 3409066 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16306698; Product type r: regulator; transcriptional regulator complement(3408353..3409066) Bacillus subtilis subsp. subtilis str. 168 935974 YP_003097787.1 CDS rsoA NC_000964.3 3409219 3409458 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18573182, 19047353; Product type r: regulator; sigma-O factor regulatory protein RsoA complement(3409219..3409458) Bacillus subtilis subsp. subtilis str. 168 8302938 NP_391203.2 CDS sigO NC_000964.3 3409462 3409992 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 18573182, 19047353; Product type r: regulator; RNA polymerase sigma factor SigO complement(3409462..3409992) Bacillus subtilis subsp. subtilis str. 168 935983 YP_003097788.1 CDS yvrJ NC_000964.3 3410007 3410345 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 18573182, 19047353; hypothetical protein 3410007..3410345 Bacillus subtilis subsp. subtilis str. 168 8303113 NP_391204.1 CDS oxdC NC_000964.3 3410466 3411623 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960116, 14697267, 14871895, 17459326, 18573182, 19047353; Product type e : enzyme; oxalate decarboxylase OxdC 3410466..3411623 Bacillus subtilis subsp. subtilis str. 168 938620 NP_391205.1 CDS yvrL NC_000964.3 3411684 3412094 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane-bound negative regulator YvrL 3411684..3412094 Bacillus subtilis subsp. subtilis str. 168 935982 NP_391207.3 CDS yvrN NC_000964.3 3412128 3413357 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter permease complement(3412128..3413357) Bacillus subtilis subsp. subtilis str. 168 937213 NP_391208.2 CDS yvrO NC_000964.3 3413350 3414039 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter; ABC transporter ATP-binding protein complement(3413350..3414039) Bacillus subtilis subsp. subtilis str. 168 938472 NP_391209.1 CDS yvrP NC_000964.3 3414023 3415216 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; efflux system protein YvrP complement(3414023..3415216) Bacillus subtilis subsp. subtilis str. 168 938618 NP_391210.1 CDS fhuC NC_000964.3 3415387 3416196 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 8388528, 8596459; Product type t : transporter; iron(3+)-hydroxamate import ATP-binding protein FhuC complement(3415387..3416196) Bacillus subtilis subsp. subtilis str. 168 935994 NP_391211.1 CDS fhuG NC_000964.3 3416212 3417222 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 15849754, 16850406, 8388528, 8596459; Product type t: transporter; iron(3+)-hydroxamate import system permease protein FhuG complement(3416212..3417222) Bacillus subtilis subsp. subtilis str. 168 938619 NP_391212.1 CDS fhuB NC_000964.3 3417222 3418376 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16850406, 8388528; Product type t: transporter; iron(3+)-hydroxamate import system permease protein FhuB complement(3417222..3418376) Bacillus subtilis subsp. subtilis str. 168 937085 NP_391213.1 CDS fhuD NC_000964.3 3418474 3419421 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 8388528; Product type t: transporter; iron(3+)-hydroxamate-binding protein FhuD 3418474..3419421 Bacillus subtilis subsp. subtilis str. 168 935996 NP_391214.1 CDS lysP NC_000964.3 3419656 3421065 R Evidence 2b: Function of strongly homologous gene; PubMedId: 14627808, 15849754, 16850406; Product type t: transporter; arginine/ornithine antiporter complement(3419656..3421065) Bacillus subtilis subsp. subtilis str. 168 936000 YP_054593.1 CDS sspJ NC_000964.3 3421465 3421605 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type cp: cell process; small acid-soluble spore protein J complement(3421465..3421605) Bacillus subtilis subsp. subtilis str. 168 2914269 NP_391215.1 CDS yvsG NC_000964.3 3421772 3422254 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; hypothetical protein 3421772..3422254 Bacillus subtilis subsp. subtilis str. 168 935995 NP_391216.1 CDS yvgJ NC_000964.3 3422354 3424207 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; lipoteichoic acid synthase 3422354..3424207 Bacillus subtilis subsp. subtilis str. 168 936006 NP_391217.1 CDS yvgK NC_000964.3 3424235 3425161 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein complement(3424235..3425161) Bacillus subtilis subsp. subtilis str. 168 936008 NP_391218.1 CDS yvgL NC_000964.3 3425272 3426054 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; ABC transporter substrate-binding protein 3425272..3426054 Bacillus subtilis subsp. subtilis str. 168 936003 NP_391219.2 CDS yvgM NC_000964.3 3426035 3426718 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; molybdenum transport system permease protein YvgM 3426035..3426718 Bacillus subtilis subsp. subtilis str. 168 936009 NP_391220.1 CDS yvgN NC_000964.3 3426749 3427579 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16232966; Product type e: enzyme; glyoxal reductase complement(3426749..3427579) Bacillus subtilis subsp. subtilis str. 168 936001 NP_391221.1 CDS yvgO NC_000964.3 3427802 3428287 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534; stress response protein YvgO 3427802..3428287 Bacillus subtilis subsp. subtilis str. 168 936024 NP_391222.1 CDS nhaK NC_000964.3 3428331 3430343 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16021482, 16850406; Product type t: transporter; sodium, potassium, lithium and rubidium/H(+) antiporter complement(3428331..3430343) Bacillus subtilis subsp. subtilis str. 168 936025 NP_391223.1 CDS yvgQ NC_000964.3 3430598 3432313 R hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase [NADPH] hemoprotein beta-component complement(3430598..3432313) Bacillus subtilis subsp. subtilis str. 168 938605 NP_391224.1 CDS cysJ NC_000964.3 3432339 3434156 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11445163, 12169591; Product type e: enzyme; sulfite reductase [NADPH] flavoprotein alpha-component complement(3432339..3434156) Bacillus subtilis subsp. subtilis str. 168 936022 NP_391225.1 CDS helD NC_000964.3 3434327 3436651 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244; Product type e: enzyme; helicase IV complement(3434327..3436651) Bacillus subtilis subsp. subtilis str. 168 936037 NP_391226.1 CDS yvgT NC_000964.3 3436849 3437457 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3436849..3437457) Bacillus subtilis subsp. subtilis str. 168 936011 NP_391227.1 CDS bdbC NC_000964.3 3437644 3438060 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455116, 11872755, 15661011, 15849754, 16751195, 16850406, 17088376; Product type e: enzyme; disulfide bond formation protein C complement(3437644..3438060) Bacillus subtilis subsp. subtilis str. 168 936042 NP_391228.1 CDS bdbD NC_000964.3 3438065 3438733 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 11872755, 12637552, 15661011, 17501922; Product type e: enzyme; disulfide bond formation protein D complement(3438065..3438733) Bacillus subtilis subsp. subtilis str. 168 936031 NP_391229.2 CDS copB NC_000964.3 3438853 3440952 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8037745, 7721839, 14663075, 12644235, 11934502, 11922674; Product type t: transporter; copper(I)-transporting ATPase complement(3438853..3440952) Bacillus subtilis subsp. subtilis str. 168 936034 NP_391230.2 CDS copA NC_000964.3 3441121 3443529 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11922674, 11934502, 12644235, 14663075, 18215122; Product type t: transporter; copper-exporting P-type ATPase A complement(3441121..3443529) Bacillus subtilis subsp. subtilis str. 168 937985 NP_391231.1 CDS copZ NC_000964.3 3443613 3443822 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934502, 12238948, 12590580, 14621987, 14663075, 15212800, 18419582; Product type f: factor; copper chaperone CopZ complement(3443613..3443822) Bacillus subtilis subsp. subtilis str. 168 937974 NP_391232.1 CDS csoR NC_000964.3 3443896 3444201 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17143269, 18048925; Product type r: regulator; copper-sensing transcriptional repressor CsoR complement(3443896..3444201) Bacillus subtilis subsp. subtilis str. 168 936038 NP_391233.1 CDS yvaA NC_000964.3 3444329 3445405 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; oxidoreductase 3444329..3445405 Bacillus subtilis subsp. subtilis str. 168 936109 NP_391234.1 CDS yvaB NC_000964.3 3445442 3446077 R FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; FMN-dependent NADH-azoreductase 2 complement(3445442..3446077) Bacillus subtilis subsp. subtilis str. 168 936142 NP_391235.1 CDS yvaC NC_000964.3 3446237 3448132 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3446237..3448132) Bacillus subtilis subsp. subtilis str. 168 936143 NP_391236.1 CDS yvaD NC_000964.3 3448295 3448696 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3448295..3448696) Bacillus subtilis subsp. subtilis str. 168 936144 NP_391237.1 CDS yvaE NC_000964.3 3448693 3449052 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11948170, 15849754, 16850406; Product type pt: transporter; membrane protein complement(3448693..3449052) Bacillus subtilis subsp. subtilis str. 168 936156 NP_391238.1 CDS yvaF NC_000964.3 3449049 3449621 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaF complement(3449049..3449621) Bacillus subtilis subsp. subtilis str. 168 936128 NP_391239.1 CDS yvaG NC_000964.3 3449732 3450526 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase complement(3449732..3450526) Bacillus subtilis subsp. subtilis str. 168 936172 NP_391240.1 CDS smpB NC_000964.3 3451248 3451718 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(3451248..3451718) Bacillus subtilis subsp. subtilis str. 168 936170 NP_391241.1 CDS rnr NC_000964.3 3451863 3454202 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399495, 15805522, 15983136; Product type e: enzyme; ribonuclease R complement(3451863..3454202) Bacillus subtilis subsp. subtilis str. 168 938644 NP_391242.1 CDS yvaK NC_000964.3 3454221 3454967 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1369099; Product type e: enzyme; carboxylesterase complement(3454221..3454967) Bacillus subtilis subsp. subtilis str. 168 938643 NP_391243.1 CDS secG NC_000964.3 3455093 3455323 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074070, 10644701, 16243836; Product type f: factor; protein-export membrane protein SecG complement(3455093..3455323) Bacillus subtilis subsp. subtilis str. 168 938477 NP_391244.1 CDS yvaM NC_000964.3 3455472 3456242 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YvaM 3455472..3456242 Bacillus subtilis subsp. subtilis str. 168 938476 NP_391245.1 CDS yvzC NC_000964.3 3456282 3456515 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvzC complement(3456282..3456515) Bacillus subtilis subsp. subtilis str. 168 936178 NP_391246.1 CDS rghRA NC_000964.3 3456667 3457074 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878, 17227471; Product type r: regulator; HTH-type transcriptional repressor RghR 3456667..3457074 Bacillus subtilis subsp. subtilis str. 168 936180 NP_391247.1 CDS rghRB NC_000964.3 3457104 3457523 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator RghRB 3457104..3457523 Bacillus subtilis subsp. subtilis str. 168 938539 NP_391248.2 CDS yvaP NC_000964.3 3457615 3457941 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaP 3457615..3457941 Bacillus subtilis subsp. subtilis str. 168 938478 NP_391249.1 CDS yvaQ NC_000964.3 3458066 3459766 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11872722, 8188684; Product type pr: regulator; sensory transducer protein YvaQ 3458066..3459766 Bacillus subtilis subsp. subtilis str. 168 938479 NP_391250.1 CDS opuBD NC_000964.3 3459806 3460486 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; choline transport system permease protein OpuBD complement(3459806..3460486) Bacillus subtilis subsp. subtilis str. 168 936226 NP_391251.1 CDS opuBC NC_000964.3 3460503 3461423 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; choline-binding protein complement(3460503..3461423) Bacillus subtilis subsp. subtilis str. 168 938475 NP_391252.1 CDS opuBB NC_000964.3 3461435 3462088 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; choline transport system permease protein OpuBB complement(3461435..3462088) Bacillus subtilis subsp. subtilis str. 168 936225 NP_391253.1 CDS opuBA NC_000964.3 3462105 3463250 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; choline transport ATP-binding protein OpuBA complement(3462105..3463250) Bacillus subtilis subsp. subtilis str. 168 936230 NP_391254.2 CDS yvaV NC_000964.3 3463534 3464067 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaV 3463534..3464067 Bacillus subtilis subsp. subtilis str. 168 936233 NP_391255.1 CDS sdpA NC_000964.3 3464289 3464765 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16469701, 17069462; Product type f: factor; sporulation-delaying protein SdpA 3464289..3464765 Bacillus subtilis subsp. subtilis str. 168 938629 NP_391256.1 CDS sdpB NC_000964.3 3464762 3465733 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16469701, 16850406, 17069462; Product type t : transporter; sporulation-delaying protein SdpB 3464762..3465733 Bacillus subtilis subsp. subtilis str. 168 936240 NP_391257.1 CDS spbC NC_000964.3 3465776 3466387 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 16469701, 17069462; Product type f: factor; killing factor SdpC 3465776..3466387 Bacillus subtilis subsp. subtilis str. 168 936227 NP_391258.1 CDS sdpI NC_000964.3 3466434 3467057 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 15849754, 16850406; Product type r: regulator; immunity protein SdpI complement(3466434..3467057) Bacillus subtilis subsp. subtilis str. 168 936238 NP_391259.1 CDS sdpR NC_000964.3 3467054 3467326 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 17069462; Product type r: regulator; transcriptional repressor SdpR complement(3467054..3467326) Bacillus subtilis subsp. subtilis str. 168 936249 NP_391260.1 CDS opuCD NC_000964.3 3467546 3468235 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport system permease protein OpuCD complement(3467546..3468235) Bacillus subtilis subsp. subtilis str. 168 937199 NP_391261.1 CDS opuCC NC_000964.3 3468253 3469164 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; glycine betaine/carnitine/choline-binding protein OpuCC complement(3468253..3469164) Bacillus subtilis subsp. subtilis str. 168 936248 NP_391262.1 CDS opuCB NC_000964.3 3469184 3469837 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport system permease protein OpuCB complement(3469184..3469837) Bacillus subtilis subsp. subtilis str. 168 937105 NP_391263.1 CDS opuCA NC_000964.3 3469860 3471002 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport ATP-binding protein OpuCA complement(3469860..3471002) Bacillus subtilis subsp. subtilis str. 168 937136 NP_391264.1 CDS yvbF NC_000964.3 3471266 3471823 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvbF 3471266..3471823 Bacillus subtilis subsp. subtilis str. 168 936258 NP_391265.1 CDS yvbG NC_000964.3 3471841 3472476 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3471841..3472476) Bacillus subtilis subsp. subtilis str. 168 938636 NP_391266.1 CDS yvbH NC_000964.3 3472626 3473240 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3472626..3473240 Bacillus subtilis subsp. subtilis str. 168 938639 NP_391267.1 CDS yvbI NC_000964.3 3473372 3474070 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 3473372..3474070 Bacillus subtilis subsp. subtilis str. 168 938638 NP_391268.1 CDS yvbJ NC_000964.3 3474106 3475923 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15155184; membrane protein complement(3474106..3475923) Bacillus subtilis subsp. subtilis str. 168 938637 NP_391269.1 CDS yvbK NC_000964.3 3476043 3476510 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YvbK 3476043..3476510 Bacillus subtilis subsp. subtilis str. 168 938642 NP_391270.1 CDS eno NC_000964.3 3476555 3477847 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; enolase complement(3476555..3477847) Bacillus subtilis subsp. subtilis str. 168 938641 NP_391271.1 CDS pgm NC_000964.3 3477877 3479412 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase complement(3477877..3479412) Bacillus subtilis subsp. subtilis str. 168 938574 NP_391272.1 CDS tpiA NC_000964.3 3479405 3480166 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(3479405..3480166) Bacillus subtilis subsp. subtilis str. 168 938626 NP_391273.1 CDS pgk NC_000964.3 3480197 3481381 R Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase complement(3480197..3481381) Bacillus subtilis subsp. subtilis str. 168 938572 NP_391274.1 CDS gapA NC_000964.3 3481698 3482705 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10799476, 12123463, 12634343, 17142398, 9588797; Product type e: enzyme; glyceraldehyde-3-phosphate dehydrogenase 1 complement(3481698..3482705) Bacillus subtilis subsp. subtilis str. 168 938627 NP_391275.1 CDS cggR NC_000964.3 3482752 3483774 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489127, 12622823, 17142398, 17293407, 18052209; Product type r: regulator; central glycolytic genes regulator complement(3482752..3483774) Bacillus subtilis subsp. subtilis str. 168 938570 NP_391276.1 CDS araE NC_000964.3 3484072 3485466 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9620981; Product type t: transporter; arabinose-proton symporter complement(3484072..3485466) Bacillus subtilis subsp. subtilis str. 168 938567 NP_391277.1 CDS araR NC_000964.3 3485604 3486758 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10417639, 11418559, 12949161, 14973026, 16585763; Product type r: regulator; transcriptional repressor 3485604..3486758 Bacillus subtilis subsp. subtilis str. 168 938635 NP_391278.1 CDS yvbT NC_000964.3 3486807 3487817 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme; hypothetical protein complement(3486807..3487817) Bacillus subtilis subsp. subtilis str. 168 938634 NP_391279.1 CDS yvbU NC_000964.3 3487974 3488852 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvbU complement(3487974..3488852) Bacillus subtilis subsp. subtilis str. 168 937711 NP_391280.1 CDS cyeB NC_000964.3 3488952 3489869 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter; transporter 3488952..3489869 Bacillus subtilis subsp. subtilis str. 168 936287 NP_391281.1 CDS yvbW NC_000964.3 3489910 3491253 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid permease YvbW complement(3489910..3491253) Bacillus subtilis subsp. subtilis str. 168 936289 NP_391282.1 CDS yvbX NC_000964.3 3491655 3492689 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177332; Product type pe : enzyme; glycosylase YvbX complement(3491655..3492689) Bacillus subtilis subsp. subtilis str. 168 937709 NP_391283.1 CDS yvbY NC_000964.3 3492797 3493519 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lactate utilization protein C complement(3492797..3493519) Bacillus subtilis subsp. subtilis str. 168 937742 NP_391284.1 CDS yvfW NC_000964.3 3493519 3494958 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lactate utilization protein B complement(3493519..3494958) Bacillus subtilis subsp. subtilis str. 168 938159 NP_391285.1 CDS yvfV NC_000964.3 3494985 3495701 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513748; Product type pe : enzyme; lactate utilization protein A complement(3494985..3495701) Bacillus subtilis subsp. subtilis str. 168 936297 NP_391286.1 CDS yvfU NC_000964.3 3495876 3496478 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator complement(3495876..3496478) Bacillus subtilis subsp. subtilis str. 168 938523 NP_391287.1 CDS yvfT NC_000964.3 3496495 3497481 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; two-component sensor histidine kinase YvfU complement(3496495..3497481) Bacillus subtilis subsp. subtilis str. 168 937702 NP_391288.1 CDS yvfS NC_000964.3 3497614 3498351 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YvfS complement(3497614..3498351) Bacillus subtilis subsp. subtilis str. 168 936302 NP_391289.1 CDS yvfR NC_000964.3 3498352 3499257 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein complement(3498352..3499257) Bacillus subtilis subsp. subtilis str. 168 936748 NP_391290.1 CDS rsbQ NC_000964.3 3499541 3500350 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591687, 12620626, 15632289; Product type r: regulator; sigma factor SigB regulation protein RsbQ 3499541..3500350 Bacillus subtilis subsp. subtilis str. 168 935930 NP_391291.1 CDS rsbP NC_000964.3 3500386 3501597 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10632888, 11591687, 15342585, 15632289, 16267279; Product type e: enzyme; phosphoserine phosphatase RsbP 3500386..3501597 Bacillus subtilis subsp. subtilis str. 168 936673 NP_391292.2 CDS ganB NC_000964.3 3501651 3502940 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178, 17056685; Product type e: enzyme; arabinogalactan endo-1,4-beta-galactosidase complement(3501651..3502940) Bacillus subtilis subsp. subtilis str. 168 937086 NP_391293.1 CDS ganA NC_000964.3 3503020 3505083 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056685, 9287030; Product type e: enzyme; arabinogalactan type I oligomer exo-hydrolase complement(3503020..3505083) Bacillus subtilis subsp. subtilis str. 168 936313 NP_391294.1 CDS ganQ NC_000964.3 3505102 3505953 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 17056685; Product type t: transporter; arabinogalactan oligomer transport system permease protein GanQ complement(3505102..3505953) Bacillus subtilis subsp. subtilis str. 168 937991 NP_391295.1 CDS ganP NC_000964.3 3505957 3507213 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160890, 15849754, 16850406, 17056685; Product type t: transporter; arabinogalactan oligomer transport system permease protein GanP complement(3505957..3507213) Bacillus subtilis subsp. subtilis str. 168 936323 NP_391296.1 CDS cycB NC_000964.3 3507253 3508518 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178; Product type t: transporter; cyclodextrin-binding protein complement(3507253..3508518) Bacillus subtilis subsp. subtilis str. 168 936329 NP_391297.1 CDS ganR NC_000964.3 3508659 3509651 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10486575, 17056685, 2104611, 9287030; Product type r: regulator; HTH-type transcriptional regulator GanR complement(3508659..3509651) Bacillus subtilis subsp. subtilis str. 168 936331 NP_391298.2 CDS yvfI NC_000964.3 3509831 3510490 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18604637; Product type pr : regulator; HTH-type transcriptional regulator LutR complement(3509831..3510490) Bacillus subtilis subsp. subtilis str. 168 936332 NP_391299.1 CDS yvfH NC_000964.3 3510780 3512471 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; L-lactate permease 3510780..3512471 Bacillus subtilis subsp. subtilis str. 168 936322 NP_391300.1 CDS sigL NC_000964.3 3512498 3513808 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109, 12533460, 12634342, 16166551, 16585774; Product type r: regulator; RNA polymerase sigma-54 factor complement(3512498..3513808) Bacillus subtilis subsp. subtilis str. 168 936362 NP_391301.1 CDS yvfG NC_000964.3 3513887 3514105 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3513887..3514105 Bacillus subtilis subsp. subtilis str. 168 936336 NP_391302.1 CDS epsO NC_000964.3 3514115 3515083 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; pyruvyl transferase EpsO complement(3514115..3515083) Bacillus subtilis subsp. subtilis str. 168 936339 NP_391303.2 CDS epsN NC_000964.3 3515062 3516228 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; pyridoxal phosphate-dependent aminotransferase EpsN complement(3515062..3516228) Bacillus subtilis subsp. subtilis str. 168 936364 NP_391304.1 CDS epsM NC_000964.3 3516233 3516883 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; acetyltransferase EpsM complement(3516233..3516883) Bacillus subtilis subsp. subtilis str. 168 936372 NP_391305.1 CDS epsL NC_000964.3 3516880 3517488 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; sugar transferase EpsL complement(3516880..3517488) Bacillus subtilis subsp. subtilis str. 168 936365 YP_003097789.1 CDS epsK NC_000964.3 3517485 3519002 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pt: transporter; membrane protein EpsK complement(3517485..3519002) Bacillus subtilis subsp. subtilis str. 168 8302980 NP_391308.1 CDS epsJ NC_000964.3 3518999 3520033 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; glycosyltransferase EpsJ complement(3518999..3520033) Bacillus subtilis subsp. subtilis str. 168 937131 NP_391309.1 CDS epsI NC_000964.3 3520030 3521106 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15173185, 15661000; Product type pe: enzyme; pyruvyl transferase EpsI complement(3520030..3521106) Bacillus subtilis subsp. subtilis str. 168 937256 NP_391310.1 CDS epsH NC_000964.3 3521111 3522145 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15083514, 15661000; Product type pe: enzyme; glycosyltransferase EpsH complement(3521111..3522145) Bacillus subtilis subsp. subtilis str. 168 938630 NP_391311.1 CDS epsG NC_000964.3 3522170 3523273 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pe: enzyme; transmembrane protein EpsG complement(3522170..3523273) Bacillus subtilis subsp. subtilis str. 168 937071 NP_391312.1 CDS epsF NC_000964.3 3523270 3524424 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsF complement(3523270..3524424) Bacillus subtilis subsp. subtilis str. 168 938631 NP_391313.2 CDS epsE NC_000964.3 3524417 3525253 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsE complement(3524417..3525253) Bacillus subtilis subsp. subtilis str. 168 938633 NP_391314.1 CDS epsD NC_000964.3 3525250 3526395 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsD complement(3525250..3526395) Bacillus subtilis subsp. subtilis str. 168 938611 NP_391315.1 CDS epsC NC_000964.3 3526407 3528203 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; polysaccharide biosynthesis protein EpsC complement(3526407..3528203) Bacillus subtilis subsp. subtilis str. 168 938571 NP_391316.1 CDS epsB NC_000964.3 3528462 3529145 R Evidence 2b: Function of strongly homologous gene; PubMedId: 15661000, 15741737; Product type e : enzyme; tyrosine-protein kinase YveL complement(3528462..3529145) Bacillus subtilis subsp. subtilis str. 168 938640 NP_391317.1 CDS epsA NC_000964.3 3529151 3529855 R Evidence 2b: Function of strongly homologous gene; PubMedId: 12970183, 15661000; Product type r : regulator; hypothetical protein complement(3529151..3529855) Bacillus subtilis subsp. subtilis str. 168 938582 NP_391318.1 CDS slrR NC_000964.3 3530101 3530559 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18430133, 18647168; Product type r: regulator; HTH-type transcriptional regulator SlrR 3530101..3530559 Bacillus subtilis subsp. subtilis str. 168 938581 NP_391319.1 CDS pnbA NC_000964.3 3530635 3532104 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7828905; Product type e : enzyme; para-nitrobenzyl esterase 3530635..3532104 Bacillus subtilis subsp. subtilis str. 168 938580 NP_391320.1 CDS padC NC_000964.3 3532325 3532810 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12903944, 17295427, 18326577; Product type e: enzyme; phenolic acid decarboxylase PadC complement(3532325..3532810) Bacillus subtilis subsp. subtilis str. 168 938579 NP_391321.1 CDS yveG NC_000964.3 3532833 3533120 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3532833..3533120) Bacillus subtilis subsp. subtilis str. 168 938578 NP_391322.1 CDS yveF NC_000964.3 3533196 3533288 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3533196..3533288) Bacillus subtilis subsp. subtilis str. 168 938614 NP_391323.1 CDS racX NC_000964.3 3533419 3534102 R Evidence 2b: Function of strongly homologous gene; PubMedId: 2054383, 9987136; Product type e : enzyme; amino acid racemase complement(3533419..3534102) Bacillus subtilis subsp. subtilis str. 168 938575 NP_391324.1 CDS pbpE NC_000964.3 3534118 3535473 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533473, 14679248, 19063962, 7592498, 9987136; Product type e: enzyme; penicillin-binding protein 4* complement(3534118..3535473) Bacillus subtilis subsp. subtilis str. 168 938615 NP_391325.1 CDS sacB NC_000964.3 3536012 3537433 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11320136, 11739774, 1400159, 15528654; Product type e: enzyme; levansucrase 3536012..3537433 Bacillus subtilis subsp. subtilis str. 168 936413 NP_391326.1 CDS levB NC_000964.3 3537507 3539057 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11739774, 15528654; Product type e: enzyme; levanbiose-producing levanase 3537507..3539057 Bacillus subtilis subsp. subtilis str. 168 938616 NP_391327.1 CDS yveA NC_000964.3 3539165 3540727 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12730183, 15528654, 15849754, 16850406; Product type t: transporter; aspartate-proton symporter 3539165..3540727 Bacillus subtilis subsp. subtilis str. 168 938612 NP_391328.1 CDS yvdT NC_000964.3 3540822 3541406 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvdT 3540822..3541406 Bacillus subtilis subsp. subtilis str. 168 936423 NP_391329.1 CDS yvdS NC_000964.3 3541488 3541823 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 3541488..3541823 Bacillus subtilis subsp. subtilis str. 168 936401 NP_391330.1 CDS yvdR NC_000964.3 3541823 3542143 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pm : membrane component; membrane protein 3541823..3542143 Bacillus subtilis subsp. subtilis str. 168 938613 NP_391331.1 CDS yvdQ NC_000964.3 3542179 3542691 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3542179..3542691) Bacillus subtilis subsp. subtilis str. 168 936432 NP_391332.1 CDS yvdP NC_000964.3 3542943 3544286 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor; FAD-linked oxidoreductase YvdP complement(3542943..3544286) Bacillus subtilis subsp. subtilis str. 168 936442 NP_391333.1 CDS cotR NC_000964.3 3544642 3545604 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650; Product type f: factor; sporulation hydrolase CotR 3544642..3545604 Bacillus subtilis subsp. subtilis str. 168 936427 NP_391334.1 CDS clpP NC_000964.3 3546234 3546827 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3546234..3546827 Bacillus subtilis subsp. subtilis str. 168 938625 NP_391335.1 CDS pgcM NC_000964.3 3546873 3547553 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11081794; Product type e: enzyme; beta-phosphoglucomutase complement(3546873..3547553) Bacillus subtilis subsp. subtilis str. 168 938624 NP_391336.1 CDS malL NC_000964.3 3547550 3549235 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10229946, 16707683, 9573215; Product type e: enzyme; oligo-1,6-glucosidase 1 complement(3547550..3549235) Bacillus subtilis subsp. subtilis str. 168 938623 NP_391337.1 CDS yvdK NC_000964.3 3549228 3551501 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type e: enzyme; maltose phosphorylase complement(3549228..3551501) Bacillus subtilis subsp. subtilis str. 168 938621 NP_391338.1 CDS yvdJ NC_000964.3 3551479 3552363 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16707683, 16850406; Product type pt: transporter; maltodextrin utilization protein YvdJ complement(3551479..3552363) Bacillus subtilis subsp. subtilis str. 168 936479 NP_391339.1 CDS mdxG NC_000964.3 3552369 3553205 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; maltodextrin transport system permease protein MdxG complement(3552369..3553205) Bacillus subtilis subsp. subtilis str. 168 936499 NP_391340.1 CDS mdxF NC_000964.3 3553206 3554513 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; maltodextrin transport system permease protein MdxF complement(3553206..3554513) Bacillus subtilis subsp. subtilis str. 168 937063 NP_391341.1 CDS mdxE NC_000964.3 3554553 3555806 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type lp: lipoprotein; maltodextrin-binding protein MdxE complement(3554553..3555806) Bacillus subtilis subsp. subtilis str. 168 936522 NP_391342.1 CDS mdxD NC_000964.3 3555902 3557671 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825545, 16707683; Product type e: enzyme; glucan 1,4-alpha-maltohexaosidase complement(3555902..3557671) Bacillus subtilis subsp. subtilis str. 168 936514 NP_391343.1 CDS mdxR NC_000964.3 3557784 3558734 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pr : regulator; HTH-type transcriptional regulator YvdE complement(3557784..3558734) Bacillus subtilis subsp. subtilis str. 168 936460 NP_391344.1 CDS yvdD NC_000964.3 3558940 3559515 R Evidence 4: Homologs of previously reported genes of unknown function; LOG family protein YvdD complement(3558940..3559515) Bacillus subtilis subsp. subtilis str. 168 936504 NP_391345.1 CDS yvdC NC_000964.3 3559632 3559952 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3559632..3559952 Bacillus subtilis subsp. subtilis str. 168 936515 NP_391346.1 CDS yvdB NC_000964.3 3559979 3561571 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sulfate transporter YvdB complement(3559979..3561571) Bacillus subtilis subsp. subtilis str. 168 937217 NP_391347.1 CDS yvdA NC_000964.3 3561590 3562183 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10611359; Product type pe : enzyme; carbonic anhydrase YvdA complement(3561590..3562183) Bacillus subtilis subsp. subtilis str. 168 937999 NP_391348.1 CDS yvcT NC_000964.3 3562566 3563543 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 2-ketogluconate reductase 3562566..3563543 Bacillus subtilis subsp. subtilis str. 168 936519 NP_391349.1 CDS yvcS NC_000964.3 3563581 3565521 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease complement(3563581..3565521) Bacillus subtilis subsp. subtilis str. 168 938473 NP_391350.1 CDS yvcR NC_000964.3 3565496 3566275 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12432961; Product type pt : transporter; ABC transporter ATP-binding protein complement(3565496..3566275) Bacillus subtilis subsp. subtilis str. 168 936524 NP_391351.1 CDS yvcQ NC_000964.3 3566358 3567428 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type rc: receptor; sensor histidine kinase complement(3566358..3567428) Bacillus subtilis subsp. subtilis str. 168 938024 NP_391352.1 CDS yvcP NC_000964.3 3567422 3568135 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type r: regulator; transcriptional regulator complement(3567422..3568135) Bacillus subtilis subsp. subtilis str. 168 936531 YP_003097790.1 CDS yvzJ NC_000964.3 3568282 3568491 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3568282..3568491 Bacillus subtilis subsp. subtilis str. 168 8303070 NP_391353.1 CDS yvcN NC_000964.3 3568527 3569291 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acetyltransferase YvcN complement(3568527..3569291) Bacillus subtilis subsp. subtilis str. 168 936525 NP_391354.1 CDS crh NC_000964.3 3569292 3569549 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559153, 10589728, 1136107, 12972249, 15126459, 16411239, 17142398; Product type r: regulator; HPr-like protein Crh complement(3569292..3569549) Bacillus subtilis subsp. subtilis str. 168 938474 NP_391355.1 CDS whiA NC_000964.3 3569573 3570523 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10986251, 17603302; Product type pr: regulator; sporulation transcription regulator WhiA complement(3569573..3570523) Bacillus subtilis subsp. subtilis str. 168 936540 NP_391356.2 CDS yvcK NC_000964.3 3570546 3571499 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11888293, 16272399; Product type f: factor; hypothetical protein complement(3570546..3571499) Bacillus subtilis subsp. subtilis str. 168 936527 NP_391357.1 CDS yvcJ NC_000964.3 3571501 3572388 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UPF0042 nucleotide-binding protein YvcJ complement(3571501..3572388) Bacillus subtilis subsp. subtilis str. 168 936532 NP_391358.1 CDS yvcI NC_000964.3 3572413 3572889 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; Nudix hydrolase YvcI complement(3572413..3572889) Bacillus subtilis subsp. subtilis str. 168 936528 NP_391359.1 CDS trxB NC_000964.3 3573207 3574157 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14597697, 15659166; Product type e: enzyme; thioredoxin complement(3573207..3574157) Bacillus subtilis subsp. subtilis str. 168 936549 NP_391360.1 CDS cwlO NC_000964.3 3574363 3575784 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 16233686; Product type e: enzyme; peptidoglycan DL-endopeptidase CwlO complement(3574363..3575784) Bacillus subtilis subsp. subtilis str. 168 936533 NP_391361.1 CDS yvcD NC_000964.3 3576165 3577619 R Evidence 4: Homologs of previously reported genes of unknown function; TPR repeat-containing protein YvcD complement(3576165..3577619) Bacillus subtilis subsp. subtilis str. 168 936542 NP_391362.1 CDS bmrA NC_000964.3 3577745 3579514 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16405427, 18215075; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein BmrA complement(3577745..3579514) Bacillus subtilis subsp. subtilis str. 168 936559 NP_391363.1 CDS yvzA NC_000964.3 3579679 3580038 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3579679..3580038) Bacillus subtilis subsp. subtilis str. 168 936541 NP_391364.1 CDS yvcB NC_000964.3 3580053 3581963 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3580053..3581963) Bacillus subtilis subsp. subtilis str. 168 936563 NP_391365.1 CDS yvcA NC_000964.3 3581965 3582690 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17590234; Product type lp : lipoprotein; lipoprotein complement(3581965..3582690) Bacillus subtilis subsp. subtilis str. 168 936576 NP_391366.1 CDS hisI NC_000964.3 3582936 3583565 R catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; histidine biosynthesis bifunctional protein HisIE complement(3582936..3583565) Bacillus subtilis subsp. subtilis str. 168 936552 NP_391367.1 CDS hisF NC_000964.3 3583562 3584320 R catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF complement(3583562..3584320) Bacillus subtilis subsp. subtilis str. 168 936554 NP_391368.1 CDS hisA NC_000964.3 3584317 3585054 R catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase complement(3584317..3585054) Bacillus subtilis subsp. subtilis str. 168 936580 NP_391369.1 CDS hisH NC_000964.3 3585051 3585689 R with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH complement(3585051..3585689) Bacillus subtilis subsp. subtilis str. 168 936590 NP_391370.1 CDS hisB NC_000964.3 3585690 3586274 R catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase complement(3585690..3586274) Bacillus subtilis subsp. subtilis str. 168 936560 NP_391371.1 CDS hisD NC_000964.3 3586271 3587554 R catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase complement(3586271..3587554) Bacillus subtilis subsp. subtilis str. 168 936584 NP_391372.1 CDS hisG NC_000964.3 3587551 3588192 R short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase complement(3587551..3588192) Bacillus subtilis subsp. subtilis str. 168 936568 NP_391373.1 CDS hisZ NC_000964.3 3588185 3589360 R May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit complement(3588185..3589360) Bacillus subtilis subsp. subtilis str. 168 936602 NP_391374.1 CDS yvpB NC_000964.3 3589611 3590363 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3589611..3590363 Bacillus subtilis subsp. subtilis str. 168 936591 NP_391375.1 CDS pelC NC_000964.3 3590603 3591268 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658655, 16514142; Product type e: enzyme; pectate lyase C 3590603..3591268 Bacillus subtilis subsp. subtilis str. 168 936594 NP_391376.1 CDS yvoF NC_000964.3 3591288 3591806 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acetyltransferase YvoF complement(3591288..3591806) Bacillus subtilis subsp. subtilis str. 168 936620 NP_391377.1 CDS hprP NC_000964.3 3591810 3592460 R hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation; pyrophosphatase PpaX complement(3591810..3592460) Bacillus subtilis subsp. subtilis str. 168 936613 NP_391378.1 CDS yvoD NC_000964.3 3592457 3593395 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3592457..3593395) Bacillus subtilis subsp. subtilis str. 168 936603 NP_391379.1 CDS lgt NC_000964.3 3593419 3594228 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(3593419..3594228) Bacillus subtilis subsp. subtilis str. 168 936609 NP_391380.1 CDS hprK NC_000964.3 3594242 3595174 R catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase complement(3594242..3595174) Bacillus subtilis subsp. subtilis str. 168 936615 NP_391381.1 CDS nagA NC_000964.3 3595356 3596546 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14557261; Product type e: enzyme; N-acetylglucosamine-6-phosphate deacetylase 3595356..3596546 Bacillus subtilis subsp. subtilis str. 168 936621 NP_391382.1 CDS nagBA NC_000964.3 3596543 3597271 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15755726; Product type e: enzyme; glucosamine-6-phosphate deaminase 1 3596543..3597271 Bacillus subtilis subsp. subtilis str. 168 936619 NP_391383.1 CDS yvoA NC_000964.3 3597289 3598020 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16207374; Product type r: regulator; HTH-type transcriptional repressor YvoA 3597289..3598020 Bacillus subtilis subsp. subtilis str. 168 936626 NP_391384.1 CDS yvnB NC_000964.3 3598040 3601909 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3598040..3601909) Bacillus subtilis subsp. subtilis str. 168 936623 NP_391385.1 CDS yvnA NC_000964.3 3602074 3602547 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvnA 3602074..3602547 Bacillus subtilis subsp. subtilis str. 168 936639 NP_391386.1 CDS cypX NC_000964.3 3602588 3603805 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; cytochrome P450 CypX complement(3602588..3603805) Bacillus subtilis subsp. subtilis str. 168 936624 NP_391387.1 CDS yvmC NC_000964.3 3603821 3604567 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3603821..3604567) Bacillus subtilis subsp. subtilis str. 168 936633 NP_391388.1 CDS yvmB NC_000964.3 3604993 3605502 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvmB 3604993..3605502 Bacillus subtilis subsp. subtilis str. 168 936625 NP_391389.1 CDS yvmA NC_000964.3 3605523 3606734 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3605523..3606734 Bacillus subtilis subsp. subtilis str. 168 936643 NP_391390.1 CDS yvlD NC_000964.3 3606762 3607121 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3606762..3607121) Bacillus subtilis subsp. subtilis str. 168 936638 NP_391391.1 CDS yvlC NC_000964.3 3607123 3607320 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; membrane protein complement(3607123..3607320) Bacillus subtilis subsp. subtilis str. 168 936642 NP_391392.1 CDS yvlB NC_000964.3 3607325 3608422 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3607325..3608422) Bacillus subtilis subsp. subtilis str. 168 936656 NP_391393.1 CDS yvlA NC_000964.3 3608447 3608773 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3608447..3608773) Bacillus subtilis subsp. subtilis str. 168 936640 NP_391394.1 CDS yvkN NC_000964.3 3608991 3609221 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3608991..3609221 Bacillus subtilis subsp. subtilis str. 168 936649 NP_391395.1 CDS yvzB NC_000964.3 3609420 3609902 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16936039; Product type ps : structure; flagellin complement(3609420..3609902) Bacillus subtilis subsp. subtilis str. 168 936664 NP_391396.1 CDS uvrA NC_000964.3 3610064 3612937 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; UvrABC system protein A complement(3610064..3612937) Bacillus subtilis subsp. subtilis str. 168 936646 NP_391397.1 CDS uvrB NC_000964.3 3612945 3614930 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; UvrABC system protein B complement(3612945..3614930) Bacillus subtilis subsp. subtilis str. 168 936663 NP_391398.1 CDS csbA NC_000964.3 3615116 3615346 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1744042; Product type pm : membrane component; general stress protein CsbA complement(3615116..3615346) Bacillus subtilis subsp. subtilis str. 168 936675 NP_391399.1 CDS yvkC NC_000964.3 3615793 3618288 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphotransferase YvkC 3615793..3618288 Bacillus subtilis subsp. subtilis str. 168 936657 NP_391400.1 CDS yvkB NC_000964.3 3618364 3618933 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvkB 3618364..3618933 Bacillus subtilis subsp. subtilis str. 168 936683 NP_391401.1 CDS yvkA NC_000964.3 3618964 3620298 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3618964..3620298 Bacillus subtilis subsp. subtilis str. 168 938566 NP_391402.1 CDS minJ NC_000964.3 3620346 3621539 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16030230, 16850406, 18976281, 19019154; Product type cp: cell process; cell division topological determinant MinJ complement(3620346..3621539) Bacillus subtilis subsp. subtilis str. 168 936668 NP_391404.1 CDS ctpB NC_000964.3 3622356 3623798 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526016, 17557826; Product type e: enzyme; carboxy-terminal processing protease CtpB complement(3622356..3623798) Bacillus subtilis subsp. subtilis str. 168 936678 NP_391405.1 CDS ftsX NC_000964.3 3623938 3624828 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process; cell division protein FtsX complement(3623938..3624828) Bacillus subtilis subsp. subtilis str. 168 936708 NP_391406.1 CDS ftsE NC_000964.3 3624821 3625507 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process; cell division ATP-binding protein FtsE complement(3624821..3625507) Bacillus subtilis subsp. subtilis str. 168 936681 NP_391407.1 CDS cccB NC_000964.3 3625741 3626079 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10473570; Product type f: factor; cytochrome c-551 complement(3625741..3626079) Bacillus subtilis subsp. subtilis str. 168 936703 NP_391408.1 CDS yvjA NC_000964.3 3626128 3626973 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10473570, 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3626128..3626973) Bacillus subtilis subsp. subtilis str. 168 938534 NP_391409.1 CDS prfB NC_000964.3 3627139 3628240 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1408743, 9696765; Product type f: factor; peptide chain release factor 2 complement(join(3627139..3628167,3628169..3628240)) Bacillus subtilis subsp. subtilis str. 168 936692 NP_391410.1 CDS secA NC_000964.3 3628310 3630835 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; protein translocase subunit SecA complement(3628310..3630835) Bacillus subtilis subsp. subtilis str. 168 936711 NP_391411.1 CDS yvyD NC_000964.3 3631003 3631572 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11948165, 16324148, 17274076, 17277072; Product type f: factor; sigma-54 modulation protein complement(3631003..3631572) Bacillus subtilis subsp. subtilis str. 168 936715 YP_003097791.1 CDS yvzG NC_000964.3 3631763 3632140 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3631763..3632140) Bacillus subtilis subsp. subtilis str. 168 8303029 NP_391412.1 CDS fliT NC_000964.3 3632150 3632491 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16952964; Product type s : structure; flagellar protein FliT complement(3632150..3632491) Bacillus subtilis subsp. subtilis str. 168 936718 NP_391413.1 CDS fliS NC_000964.3 3632488 3632889 R flagellin specific chaperone; flagellar protein FliS complement(3632488..3632889) Bacillus subtilis subsp. subtilis str. 168 936720 NP_391414.1 CDS fliD NC_000964.3 3632911 3634407 R involved in flagellin assembly; flagellar hook-associated protein 2 complement(3632911..3634407) Bacillus subtilis subsp. subtilis str. 168 936728 NP_391415.1 CDS yvyC NC_000964.3 3634425 3634754 R possibly involved in flagella export; hypothetical protein complement(3634425..3634754) Bacillus subtilis subsp. subtilis str. 168 936737 NP_391416.1 CDS hag NC_000964.3 3634987 3635901 R structural flagella protein; flagellin complement(3634987..3635901) Bacillus subtilis subsp. subtilis str. 168 936742 NP_391417.1 CDS csrA NC_000964.3 3636046 3636270 R affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator homolog complement(3636046..3636270) Bacillus subtilis subsp. subtilis str. 168 936731 NP_391418.1 CDS yviF NC_000964.3 3636264 3636695 R binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly factor FliW complement(3636264..3636695) Bacillus subtilis subsp. subtilis str. 168 936732 NP_391419.1 CDS yviE NC_000964.3 3636716 3637291 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein complement(3636716..3637291) Bacillus subtilis subsp. subtilis str. 168 936735 NP_391420.1 CDS flgL NC_000964.3 3637338 3638234 R with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein 3 complement(3637338..3638234) Bacillus subtilis subsp. subtilis str. 168 936738 NP_391421.1 CDS flgK NC_000964.3 3638245 3639768 R with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein 1 complement(3638245..3639768) Bacillus subtilis subsp. subtilis str. 168 936736 NP_391422.1 CDS yvyG NC_000964.3 3639787 3640269 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein complement(3639787..3640269) Bacillus subtilis subsp. subtilis str. 168 936745 NP_391423.1 CDS flgM NC_000964.3 3640285 3640551 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10207036, 10322161, 14762011, 16673084; Product type r: regulator; negative regulator of flagellin synthesis complement(3640285..3640551) Bacillus subtilis subsp. subtilis str. 168 936739 NP_391424.1 CDS yvyF NC_000964.3 3640632 3641051 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696775; Product type pr : regulator; hypothetical protein complement(3640632..3641051) Bacillus subtilis subsp. subtilis str. 168 936743 NP_391425.1 CDS comFC NC_000964.3 3641125 3641814 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16009133, 8045879, 8412657; Product type pt: transporter; ComF operon protein 3 complement(3641125..3641814) Bacillus subtilis subsp. subtilis str. 168 936747 NP_391426.1 CDS comFB NC_000964.3 3641811 3642107 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16009133, 8045879, 8412657; ComF operon protein 2 complement(3641811..3642107) Bacillus subtilis subsp. subtilis str. 168 936749 NP_391427.1 CDS comFA NC_000964.3 3642167 3643558 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 12123453, 16009133, 8045895; Product type e: enzyme; ComF operon protein 1 complement(3642167..3643558) Bacillus subtilis subsp. subtilis str. 168 938537 NP_391428.1 CDS yviA NC_000964.3 3643664 3644509 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17114254, 3926750; protein DegV complement(3643664..3644509) Bacillus subtilis subsp. subtilis str. 168 936763 NP_391429.1 CDS degU NC_000964.3 3644607 3645296 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897; Product type r: regulator; transcriptional regulatory protein DegU complement(3644607..3645296) Bacillus subtilis subsp. subtilis str. 168 936751 NP_391430.1 CDS degS NC_000964.3 3645379 3646536 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12183369, 12471443, 12950930, 14563871; Product type rc: receptor; signal transduction histidine-protein kinase/phosphatase DegS complement(3645379..3646536) Bacillus subtilis subsp. subtilis str. 168 936752 NP_391431.1 CDS yvyE NC_000964.3 3646753 3647406 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11116084; IMPACT family member YvyE 3646753..3647406 Bacillus subtilis subsp. subtilis str. 168 936754 NP_391432.1 CDS yvhJ NC_000964.3 3647406 3648581 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator YvhJ 3647406..3648581 Bacillus subtilis subsp. subtilis str. 168 936761 NP_391433.1 CDS tagO NC_000964.3 3648654 3649730 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12101296, 12682299, 15849754, 16850406, 17012386, 18156271; Product type e: enzyme; undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase complement(3648654..3649730) Bacillus subtilis subsp. subtilis str. 168 936757 NP_391434.1 CDS tuaH NC_000964.3 3649875 3651068 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaH complement(3649875..3651068) Bacillus subtilis subsp. subtilis str. 168 938535 NP_391435.1 CDS tuaG NC_000964.3 3651097 3651855 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaG complement(3651097..3651855) Bacillus subtilis subsp. subtilis str. 168 937965 NP_391436.1 CDS tuaF NC_000964.3 3651879 3652559 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis protein TuaF complement(3651879..3652559) Bacillus subtilis subsp. subtilis str. 168 936768 NP_391437.1 CDS tuaE NC_000964.3 3652588 3654054 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis protein TuaE complement(3652588..3654054) Bacillus subtilis subsp. subtilis str. 168 936765 NP_391438.1 CDS tuaD NC_000964.3 3654139 3655524 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376820, 10913081, 12970183, 16000785; Product type e: enzyme; UDP-glucose 6-dehydrogenase TuaD complement(3654139..3655524) Bacillus subtilis subsp. subtilis str. 168 936766 NP_391439.1 CDS tuaC NC_000964.3 3655586 3656755 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaC complement(3655586..3656755) Bacillus subtilis subsp. subtilis str. 168 936771 NP_391440.1 CDS tuaB NC_000964.3 3656752 3658203 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406; Product type pt: transporter; teichuronic acid biosynthesis protein TuaB complement(3656752..3658203) Bacillus subtilis subsp. subtilis str. 168 936770 NP_391442.1 CDS lytC NC_000964.3 3659119 3660609 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079, 14594841, 17298895, 9537764; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase LytC complement(3659119..3660609) Bacillus subtilis subsp. subtilis str. 168 936777 NP_391443.1 CDS lytB NC_000964.3 3660648 3662765 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079; Product type r : regulator; amidase enhancer complement(3660648..3662765) Bacillus subtilis subsp. subtilis str. 168 936795 NP_391444.1 CDS lytA NC_000964.3 3662789 3663097 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974124, 1357079; Product type lp: lipoprotein; membrane-bound protein LytA complement(3662789..3663097) Bacillus subtilis subsp. subtilis str. 168 936784 NP_391445.1 CDS lytR NC_000964.3 3663281 3664201 D attenuator function for control of operon expression; transcriptional regulator LytR 3663281..3664201 Bacillus subtilis subsp. subtilis str. 168 936787 NP_391446.1 CDS mnaA NC_000964.3 3664241 3665383 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12107153; Product type e: enzyme; UDP-N-acetylglucosamine 2-epimerase complement(3664241..3665383) Bacillus subtilis subsp. subtilis str. 168 936209 NP_391447.1 CDS gtaB NC_000964.3 3665629 3666507 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17662947, 2846750, 8126437, 8320212, 9658024; Product type e: enzyme; UTP--glucose-1-phosphate uridylyltransferase 3665629..3666507 Bacillus subtilis subsp. subtilis str. 168 936797 NP_391448.1 CDS ggaB NC_000964.3 3667209 3669911 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16735734; Product type e: enzyme; minor teichoic acid biosynthesis protein GgaB complement(3667209..3669911) Bacillus subtilis subsp. subtilis str. 168 936775 NP_391449.1 CDS ggaA NC_000964.3 3670035 3671375 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16735734, 7704262; Product type e: enzyme; minor teichoic acid biosynthesis protein GgaA complement(3670035..3671375) Bacillus subtilis subsp. subtilis str. 168 936798 NP_391451.1 CDS tagH NC_000964.3 3673564 3675147 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17012386, 18156271, 7565096; Product type t: transporter; teichoic acids export ATP-binding protein TagH complement(3673564..3675147) Bacillus subtilis subsp. subtilis str. 168 936513 NP_391452.1 CDS tagG NC_000964.3 3675167 3675994 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406, 17012386, 18156271, 7565096; Product type t: transporter; teichoic acid translocation permease protein TagG complement(3675167..3675994) Bacillus subtilis subsp. subtilis str. 168 936794 NP_391453.1 CDS tagF NC_000964.3 3676159 3678399 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386; Product type e: enzyme; CDP-glycerol:poly complement(3676159..3678399) Bacillus subtilis subsp. subtilis str. 168 936803 NP_391454.1 CDS tagE NC_000964.3 3678399 3680420 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386, 2507871, 9457886; Product type e : enzyme; poly(glycerol-phosphate) alpha-glucosyltransferase complement(3678399..3680420) Bacillus subtilis subsp. subtilis str. 168 936804 NP_391455.1 CDS tagD NC_000964.3 3680581 3680970 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11673441, 12637027, 12637499, 12682299, 16141206, 16689786, 17012386; Product type e: enzyme; glycerol-3-phosphate cytidylyltransferase complement(3680581..3680970) Bacillus subtilis subsp. subtilis str. 168 936809 NP_391456.1 CDS tagA NC_000964.3 3681370 3682140 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 16953575, 17012386; Product type e: enzyme; N-acetylmannosaminyltransferase 3681370..3682140 Bacillus subtilis subsp. subtilis str. 168 936810 NP_391457.1 CDS tagB NC_000964.3 3682173 3683318 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16141206, 16150696, 16689786, 17012386, 18156271; Product type e: enzyme; CDP-glycerol:glycerophosphate glycerophosphotransferase 3682173..3683318 Bacillus subtilis subsp. subtilis str. 168 936813 NP_391458.1 CDS tagC NC_000964.3 3683438 3684766 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16269821, 7952180; Product type pe: enzyme; major teichoic acid biosynthesis protein C 3683438..3684766 Bacillus subtilis subsp. subtilis str. 168 936812 NP_391459.1 CDS lytD NC_000964.3 3684826 3687468 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537764, 10206711; Product type e: enzyme; beta-N-acetylglucosaminidase complement(3684826..3687468) Bacillus subtilis subsp. subtilis str. 168 936822 NP_391460.1 CDS yvyI NC_000964.3 3687597 3688547 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478, 7581999; Product type e: enzyme; mannose-6-phosphate isomerase YvyI complement(3687597..3688547) Bacillus subtilis subsp. subtilis str. 168 936815 NP_391461.2 CDS gerBA NC_000964.3 3688812 3690263 D Evidence 1c: Function experimentally demonstrated in the studied genus; PubMedId: 10411756, 15774895, 3110007, 8012571; Product type rc: receptor; spore germination protein B1 3688812..3690263 Bacillus subtilis subsp. subtilis str. 168 936814 NP_391462.2 CDS gerBB NC_000964.3 3690269 3691375 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16352818, 16850406; Product type rc: receptor; spore germination protein B2 3690269..3691375 Bacillus subtilis subsp. subtilis str. 168 936827 NP_391463.1 CDS gerBC NC_000964.3 3691372 3692496 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 16352818; Product type lp: lipoprotein; spore germination protein B3 3691372..3692496 Bacillus subtilis subsp. subtilis str. 168 936819 NP_391464.2 CDS ywtG NC_000964.3 3692533 3693906 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transport protein YwtG complement(3692533..3693906) Bacillus subtilis subsp. subtilis str. 168 936832 NP_391465.2 CDS ywtF NC_000964.3 3694239 3695207 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator YwtF 3694239..3695207 Bacillus subtilis subsp. subtilis str. 168 936823 NP_391466.1 CDS ywtE NC_000964.3 3695363 3696223 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3695363..3696223 Bacillus subtilis subsp. subtilis str. 168 936824 NP_391467.1 CDS pgdS NC_000964.3 3696257 3697498 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073126, 12644511; Product type e: enzyme; gamma-dl-glutamyl hydrolase complement(3696257..3697498) Bacillus subtilis subsp. subtilis str. 168 936837 NP_391468.1 CDS pgsE NC_000964.3 3697639 3697806 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16267300; Product type f: factor; hypothetical protein complement(3697639..3697806) Bacillus subtilis subsp. subtilis str. 168 936828 NP_391469.1 CDS pgsA NC_000964.3 3697821 3698963 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 12644511; Product type e: enzyme; PGA biosynthesis protein CapA complement(3697821..3698963) Bacillus subtilis subsp. subtilis str. 168 936830 NP_391470.1 CDS pgsC NC_000964.3 3698982 3699431 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 15849754, 16689787, 16850406; Product type e: enzyme; PGA biosynthesis protein CapC complement(3698982..3699431) Bacillus subtilis subsp. subtilis str. 168 936840 NP_391471.2 CDS pgsB NC_000964.3 3699446 3700627 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11606194, 11751809, 12644511; Product type e : enzyme; PGA synthase CapB complement(3699446..3700627) Bacillus subtilis subsp. subtilis str. 168 936833 NP_391472.1 CDS rbsR NC_000964.3 3701411 3702391 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16519689; Product type r: regulator; ribose operon repressor 3701411..3702391 Bacillus subtilis subsp. subtilis str. 168 936836 NP_391473.1 CDS rbsK NC_000964.3 3702393 3703274 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16978644, 7921236; Product type e: enzyme; ribokinase 3702393..3703274 Bacillus subtilis subsp. subtilis str. 168 936844 NP_391474.1 CDS rbsD NC_000964.3 3703271 3703666 D cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 3703271..3703666 Bacillus subtilis subsp. subtilis str. 168 936846 NP_391475.1 CDS rbsA NC_000964.3 3703682 3705163 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter; ribose import ATP-binding protein RbsA 3703682..3705163 Bacillus subtilis subsp. subtilis str. 168 936839 NP_391476.1 CDS rbsC NC_000964.3 3705165 3706133 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7921236; Product type t: transporter; ribose transport system permease RbsC 3705165..3706133 Bacillus subtilis subsp. subtilis str. 168 936841 NP_391477.1 CDS rbsB NC_000964.3 3706145 3707062 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter; D-ribose-binding protein 3706145..3707062 Bacillus subtilis subsp. subtilis str. 168 936848 NP_391478.1 CDS ywsB NC_000964.3 3707144 3707680 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15187182; cell wall-binding protein YwsB 3707144..3707680 Bacillus subtilis subsp. subtilis str. 168 936850 NP_391479.1 CDS ywsA NC_000964.3 3707836 3708132 D Evidence 5: No homology to any previously reported sequences; PubMedId: 11782522; hypothetical protein 3707836..3708132 Bacillus subtilis subsp. subtilis str. 168 936847 NP_391480.1 CDS ywrO NC_000964.3 3708172 3708699 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11782522; Product type e: enzyme; general stress protein 14 complement(3708172..3708699) Bacillus subtilis subsp. subtilis str. 168 936853 NP_391481.1 CDS alsD NC_000964.3 3708799 3709566 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972805, 12363365, 17183216, 7685336; Product type e: enzyme; alpha-acetolactate decarboxylase complement(3708799..3709566) Bacillus subtilis subsp. subtilis str. 168 936857 NP_391482.2 CDS alsS NC_000964.3 3709628 3711340 R catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase complement(3709628..3711340) Bacillus subtilis subsp. subtilis str. 168 936852 NP_391483.1 CDS alsR NC_000964.3 3711498 3712406 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 10972805, 12363365, 15978075, 17183216, 7685336; Product type r : regulator; HTH-type transcriptional regulator AlsR 3711498..3712406 Bacillus subtilis subsp. subtilis str. 168 936860 NP_391484.1 CDS ywrK NC_000964.3 3712617 3713945 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; arsenical pump membrane protein 3712617..3713945 Bacillus subtilis subsp. subtilis str. 168 936864 NP_391485.1 CDS ywrJ NC_000964.3 3714002 3714679 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14762006; hypothetical protein complement(3714002..3714679) Bacillus subtilis subsp. subtilis str. 168 936867 NP_391486.1 CDS cotB NC_000964.3 3714739 3715881 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559171, 11737650, 14762006, 8755863; Product type f: factor; spore coat protein B complement(3714739..3715881) Bacillus subtilis subsp. subtilis str. 168 936870 NP_391487.1 CDS cotH NC_000964.3 3716009 3717097 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762006; Product type f: factor; inner spore coat protein H complement(3716009..3717097) Bacillus subtilis subsp. subtilis str. 168 936858 NP_391488.1 CDS cotG NC_000964.3 3717238 3717825 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14762006, 15621419; Product type cp: cell process; spore coat protein G 3717238..3717825 Bacillus subtilis subsp. subtilis str. 168 936865 NP_391489.1 CDS ywrF NC_000964.3 3717999 3718616 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3717999..3718616 Bacillus subtilis subsp. subtilis str. 168 936871 NP_391490.1 CDS ywrE NC_000964.3 3718794 3719129 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3718794..3719129 Bacillus subtilis subsp. subtilis str. 168 936874 NP_391491.1 CDS ywrD NC_000964.3 3719134 3720711 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762019; Product type pe : enzyme; gamma-glutamyltransferase YwrD complement(3719134..3720711) Bacillus subtilis subsp. subtilis str. 168 936884 NP_391492.1 CDS ywrC NC_000964.3 3720925 3721401 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwrC 3720925..3721401 Bacillus subtilis subsp. subtilis str. 168 936886 NP_391493.1 CDS ywrB NC_000964.3 3721415 3722008 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3721415..3722008 Bacillus subtilis subsp. subtilis str. 168 936876 NP_391494.1 CDS ywrA NC_000964.3 3722005 3722541 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3722005..3722541 Bacillus subtilis subsp. subtilis str. 168 936879 NP_391495.1 CDS ywqO NC_000964.3 3722568 3722789 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3722568..3722789) Bacillus subtilis subsp. subtilis str. 168 936881 NP_391496.1 CDS ywqN NC_000964.3 3722786 3723331 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H-dependent FMN-containing oxidoreductase YwqN complement(3722786..3723331) Bacillus subtilis subsp. subtilis str. 168 936882 NP_391497.1 CDS ywqM NC_000964.3 3723454 3724335 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwqM 3723454..3724335 Bacillus subtilis subsp. subtilis str. 168 936887 NP_391498.2 CDS ywqL NC_000964.3 3724420 3725136 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1692969; Product type pe : enzyme; endonuclease V complement(3724420..3725136) Bacillus subtilis subsp. subtilis str. 168 936894 NP_391499.1 CDS ywqK NC_000964.3 3725146 3725610 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3725146..3725610) Bacillus subtilis subsp. subtilis str. 168 936888 NP_391500.1 CDS ywqJ NC_000964.3 3725600 3727408 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(3725600..3727408) Bacillus subtilis subsp. subtilis str. 168 936885 NP_391501.1 CDS ywqI NC_000964.3 3727427 3727687 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3727427..3727687) Bacillus subtilis subsp. subtilis str. 168 937912 NP_391502.1 CDS ywqH NC_000964.3 3727697 3728119 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15101989; hypothetical protein complement(3727697..3728119) Bacillus subtilis subsp. subtilis str. 168 937905 NP_391503.1 CDS ywqG NC_000964.3 3728511 3729296 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3728511..3729296) Bacillus subtilis subsp. subtilis str. 168 937891 NP_391504.1 CDS ywqF NC_000964.3 3729488 3730810 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15741737, 15866923, 16415592; Product type e: enzyme; UDP-glucose 6-dehydrogenase YwqF complement(3729488..3730810) Bacillus subtilis subsp. subtilis str. 168 936890 NP_391505.1 CDS ywqE NC_000964.3 3731005 3731769 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15866923, 16415592, 16549871; Product type e: enzyme; tyrosine-protein phosphatase YwqE complement(3731005..3731769) Bacillus subtilis subsp. subtilis str. 168 936893 NP_391506.1 CDS ptkA NC_000964.3 3731822 3732535 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183, 15741737, 16415592, 16549871, 17367396; Product type e: enzyme; tyrosine-protein kinase YwqD complement(3731822..3732535) Bacillus subtilis subsp. subtilis str. 168 936896 NP_391507.1 CDS ywqC NC_000964.3 3732525 3733271 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183; Product type f: factor; capsular polysaccharide biosynthesis protein YwqC complement(3732525..3733271) Bacillus subtilis subsp. subtilis str. 168 936897 YP_003097792.1 CDS ywzD NC_000964.3 3733505 3733648 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3733505..3733648) Bacillus subtilis subsp. subtilis str. 168 8303126 NP_391508.2 CDS ywqB NC_000964.3 3733852 3735462 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3733852..3735462 Bacillus subtilis subsp. subtilis str. 168 936903 NP_391509.1 CDS ywqA NC_000964.3 3735449 3738217 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; ATP-dependent helicase YwqA 3735449..3738217 Bacillus subtilis subsp. subtilis str. 168 936906 NP_391510.1 CDS ywpJ NC_000964.3 3738343 3739200 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YwpJ complement(3738343..3739200) Bacillus subtilis subsp. subtilis str. 168 936907 NP_391511.1 CDS glcR NC_000964.3 3739206 3739982 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11491085; Product type r: regulator; HTH-type transcriptional repressor GlcR complement(3739206..3739982) Bacillus subtilis subsp. subtilis str. 168 936908 NP_391512.2 CDS ssbB NC_000964.3 3740206 3740547 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762004, 16009133, 16549871; Product type f : factor; single-stranded DNA-binding protein SsbB complement(3740206..3740547) Bacillus subtilis subsp. subtilis str. 168 936910 NP_391513.1 CDS ywpG NC_000964.3 3740624 3741007 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3740624..3741007) Bacillus subtilis subsp. subtilis str. 168 936912 NP_391514.1 CDS ywpF NC_000964.3 3741182 3741592 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3741182..3741592 Bacillus subtilis subsp. subtilis str. 168 936915 NP_391515.1 CDS ywpE NC_000964.3 3741732 3742040 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; sortase complement(3741732..3742040) Bacillus subtilis subsp. subtilis str. 168 936904 NP_391516.1 CDS ywpD NC_000964.3 3742384 3743220 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16740923; Product type prc : receptor; hypothetical protein 3742384..3743220 Bacillus subtilis subsp. subtilis str. 168 936914 NP_391517.1 CDS mscL NC_000964.3 3743267 3743659 R homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel complement(3743267..3743659) Bacillus subtilis subsp. subtilis str. 168 936909 NP_391518.2 CDS fabZ NC_000964.3 3743732 3744157 R in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ complement(3743732..3744157) Bacillus subtilis subsp. subtilis str. 168 936918 NP_391519.1 CDS rapD NC_000964.3 3744349 3745413 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17227471; Product type r: regulator; response regulator aspartate phosphatase D 3744349..3745413 Bacillus subtilis subsp. subtilis str. 168 936919 NP_391520.2 CDS flhP NC_000964.3 3745436 3746245 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; flagellar hook-basal body complex protein FlhP complement(3745436..3746245) Bacillus subtilis subsp. subtilis str. 168 936913 NP_391521.1 CDS flhO NC_000964.3 3746279 3747091 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16621824, 1905667; Product type ps: structure; flagellar hook-basal body complex protein FlhO complement(3746279..3747091) Bacillus subtilis subsp. subtilis str. 168 936927 NP_391522.2 CDS mbl NC_000964.3 3747254 3748255 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11290328, 12530960, 14588250, 15745453, 17064365; Product type f: factor; MreB-like protein complement(3747254..3748255) Bacillus subtilis subsp. subtilis str. 168 936916 NP_391523.1 CDS spoIIID NC_000964.3 3748421 3748702 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15598884, 9023218, 9324264; Product type r: regulator; stage III sporulation protein D complement(3748421..3748702) Bacillus subtilis subsp. subtilis str. 168 936917 NP_391524.1 CDS usd NC_000964.3 3748717 3748827 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9023218; Product type ph : phenotype; protein usd complement(3748717..3748827) Bacillus subtilis subsp. subtilis str. 168 938188 NP_391525.1 CDS ywoH NC_000964.3 3749052 3749465 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwoH 3749052..3749465 Bacillus subtilis subsp. subtilis str. 168 936923 NP_391526.1 CDS ywoG NC_000964.3 3749487 3750677 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3749487..3750677 Bacillus subtilis subsp. subtilis str. 168 936928 NP_391527.1 CDS ywoF NC_000964.3 3750768 3752174 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15266115; Product type pe : enzyme; hypothetical protein complement(3750768..3752174) Bacillus subtilis subsp. subtilis str. 168 936925 NP_391528.1 CDS pucI NC_000964.3 3752280 3753752 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 15849754, 16850406; Product type t: transporter; allantoin permease complement(3752280..3753752) Bacillus subtilis subsp. subtilis str. 168 936935 NP_391529.1 CDS ywoD NC_000964.3 3753933 3755291 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter complement(3753933..3755291) Bacillus subtilis subsp. subtilis str. 168 938533 NP_391530.2 CDS ywoC NC_000964.3 3755291 3755860 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase complement(3755291..3755860) Bacillus subtilis subsp. subtilis str. 168 936934 NP_391531.1 CDS ywoB NC_000964.3 3756044 3756508 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3756044..3756508) Bacillus subtilis subsp. subtilis str. 168 936938 NP_391532.1 CDS amtB NC_000964.3 3756790 3758004 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 15849754, 16850406, 17001076; Product type t: transporter; ammonium transporter NrgA 3756790..3758004 Bacillus subtilis subsp. subtilis str. 168 936933 NP_391533.1 CDS glnK NC_000964.3 3758016 3758366 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 17001076; Product type r: regulator; nitrogen regulatory PII-like protein 3758016..3758366 Bacillus subtilis subsp. subtilis str. 168 936937 NP_391534.1 CDS bcrC NC_000964.3 3758547 3759128 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486040, 14612242, 15838020, 15849754, 15946938, 16850406; Product type e : enzyme; undecaprenyl-diphosphatase BcrC 3758547..3759128 Bacillus subtilis subsp. subtilis str. 168 936946 NP_391535.1 CDS ywnJ NC_000964.3 3759169 3759591 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762009, 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3759169..3759591) Bacillus subtilis subsp. subtilis str. 168 936936 NP_391536.1 CDS spoIIQ NC_000964.3 3759702 3760553 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16164552, 16959571, 17121846, 18077456; Product type f: factor; stage II sporulation protein Q complement(3759702..3760553) Bacillus subtilis subsp. subtilis str. 168 936951 NP_391537.1 CDS ywnH NC_000964.3 3760694 3761185 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; phosphinothricin acetyltransferase YwnH 3760694..3761185 Bacillus subtilis subsp. subtilis str. 168 936956 NP_391538.1 CDS ywnG NC_000964.3 3761182 3761700 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3761182..3761700 Bacillus subtilis subsp. subtilis str. 168 936941 NP_391539.1 CDS ywnF NC_000964.3 3761987 3762421 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3761987..3762421) Bacillus subtilis subsp. subtilis str. 168 936942 NP_391540.1 CDS clsA NC_000964.3 3762664 3764112 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme; cardiolipin synthase 3762664..3764112 Bacillus subtilis subsp. subtilis str. 168 936957 NP_391541.1 CDS mta NC_000964.3 3764133 3764906 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 11581256; Product type r: regulator; HTH-type transcriptional activator mta complement(3764133..3764906) Bacillus subtilis subsp. subtilis str. 168 936962 NP_391542.1 CDS ywnC NC_000964.3 3765051 3765434 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3765051..3765434 Bacillus subtilis subsp. subtilis str. 168 936950 NP_391543.1 CDS ywnB NC_000964.3 3765469 3766110 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3765469..3766110) Bacillus subtilis subsp. subtilis str. 168 936961 NP_391544.1 CDS ywnA NC_000964.3 3766178 3766579 R Evidence 4: Homologs of previously reported genes of unknown function; HTH-type transcriptional regulator YwnA complement(3766178..3766579) Bacillus subtilis subsp. subtilis str. 168 936952 NP_391545.1 CDS ureC NC_000964.3 3766714 3768423 R ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha complement(3766714..3768423) Bacillus subtilis subsp. subtilis str. 168 936958 NP_391546.1 CDS ureB NC_000964.3 3768420 3768794 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12401490, 16199586, 9287005; Product type e: enzyme; urease subunit beta complement(3768420..3768794) Bacillus subtilis subsp. subtilis str. 168 936967 NP_391547.1 CDS ureA NC_000964.3 3768791 3769108 R UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma complement(3768791..3769108) Bacillus subtilis subsp. subtilis str. 168 936968 NP_391548.1 CDS csbD NC_000964.3 3770104 3770292 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376822, 11988534; Product type f: factor; stress response protein CsbD complement(3770104..3770292) Bacillus subtilis subsp. subtilis str. 168 936969 NP_391549.2 CDS ywmF NC_000964.3 3770365 3770865 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3770365..3770865) Bacillus subtilis subsp. subtilis str. 168 936974 NP_391550.1 CDS rapB NC_000964.3 3771000 3772133 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 12875849, 9843420; Product type e: enzyme; response regulator aspartate phosphatase B complement(3771000..3772133) Bacillus subtilis subsp. subtilis str. 168 936963 NP_391551.1 CDS moaA NC_000964.3 3772325 3773350 R together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; cyclic pyranopterin monophosphate synthase complement(3772325..3773350) Bacillus subtilis subsp. subtilis str. 168 936982 NP_391552.1 CDS fdhD NC_000964.3 3773366 3774154 R involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; protein FdhD homolog complement(3773366..3774154) Bacillus subtilis subsp. subtilis str. 168 936976 NP_391553.1 CDS ywmE NC_000964.3 3774400 3774561 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3774400..3774561) Bacillus subtilis subsp. subtilis str. 168 936977 NP_391554.1 CDS ywmD NC_000964.3 3774655 3775329 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(3774655..3775329) Bacillus subtilis subsp. subtilis str. 168 936987 NP_391555.1 CDS ywmC NC_000964.3 3775653 3776336 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(3775653..3776336) Bacillus subtilis subsp. subtilis str. 168 936990 NP_391556.1 CDS spoIID NC_000964.3 3776722 3777753 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15752199, 16959571, 17376078; Product type cp: cell process; stage II sporulation protein D complement(3776722..3777753) Bacillus subtilis subsp. subtilis str. 168 936979 NP_391557.1 CDS murAA NC_000964.3 3777949 3779259 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 complement(3777949..3779259) Bacillus subtilis subsp. subtilis str. 168 936980 NP_391558.1 CDS ywmB NC_000964.3 3779293 3780033 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3779293..3780033) Bacillus subtilis subsp. subtilis str. 168 936983 NP_391559.1 CDS ywzB NC_000964.3 3780162 3780392 R Evidence 4: Homologs of previously reported genes of unknown function; membrane protein complement(3780162..3780392) Bacillus subtilis subsp. subtilis str. 168 936986 NP_391560.1 CDS ywmA NC_000964.3 3780562 3781035 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 3780562..3781035 Bacillus subtilis subsp. subtilis str. 168 936991 NP_391561.1 CDS atpC NC_000964.3 3781069 3781467 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase epsilon chain complement(3781069..3781467) Bacillus subtilis subsp. subtilis str. 168 936994 NP_391562.1 CDS atpD NC_000964.3 3781491 3782912 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase subunit beta complement(3781491..3782912) Bacillus subtilis subsp. subtilis str. 168 936992 NP_391563.1 CDS atpG NC_000964.3 3782938 3783801 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase gamma chain complement(3782938..3783801) Bacillus subtilis subsp. subtilis str. 168 936989 NP_391564.1 CDS atpA NC_000964.3 3783878 3785386 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase subunit alpha complement(3783878..3785386) Bacillus subtilis subsp. subtilis str. 168 936995 NP_391565.1 CDS atpH NC_000964.3 3785403 3785948 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase subunit delta complement(3785403..3785948) Bacillus subtilis subsp. subtilis str. 168 936997 NP_391566.1 CDS atpF NC_000964.3 3785945 3786457 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase subunit b complement(3785945..3786457) Bacillus subtilis subsp. subtilis str. 168 936998 NP_391567.1 CDS atpE NC_000964.3 3786620 3786832 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase subunit c complement(3786620..3786832) Bacillus subtilis subsp. subtilis str. 168 936999 NP_391568.1 CDS atpB NC_000964.3 3786878 3787612 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase subunit a complement(3786878..3787612) Bacillus subtilis subsp. subtilis str. 168 937004 NP_391569.1 CDS atpI NC_000964.3 3787620 3788003 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12917488, 15849754, 16850406; Product type t: transporter; ATP synthase protein I complement(3787620..3788003) Bacillus subtilis subsp. subtilis str. 168 937003 NP_391570.1 CDS upp NC_000964.3 3788426 3789055 R Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase complement(3788426..3789055) Bacillus subtilis subsp. subtilis str. 168 937006 NP_391571.1 CDS glyA NC_000964.3 3789190 3790437 R catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase complement(3789190..3790437) Bacillus subtilis subsp. subtilis str. 168 937015 NP_391572.1 CDS ywlG NC_000964.3 3790644 3791186 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210; hypothetical protein complement(3790644..3791186) Bacillus subtilis subsp. subtilis str. 168 937007 NP_391573.1 CDS ywlF NC_000964.3 3791199 3791648 R catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; sugar phosphate isomerase YwlF complement(3791199..3791648) Bacillus subtilis subsp. subtilis str. 168 937014 NP_391574.1 CDS ywlE NC_000964.3 3791805 3792257 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme; low molecular weight protein-tyrosine-phosphatase YwlE complement(3791805..3792257) Bacillus subtilis subsp. subtilis str. 168 937021 NP_391575.1 CDS ywlD NC_000964.3 3792333 3792890 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3792333..3792890) Bacillus subtilis subsp. subtilis str. 168 937022 NP_391576.1 CDS ywlC NC_000964.3 3792969 3794009 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 16890019, 17005971; Product type pf: factor; tRNA threonylcarbamoyladenosine biosynthesis protein YwlC complement(3792969..3794009) Bacillus subtilis subsp. subtilis str. 168 937023 NP_391577.1 CDS ywlB NC_000964.3 3794166 3794609 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3794166..3794609) Bacillus subtilis subsp. subtilis str. 168 937028 NP_391578.1 CDS spoIIR NC_000964.3 3794676 3795350 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 16824103; Product type e: enzyme; stage II sporulation protein R complement(3794676..3795350) Bacillus subtilis subsp. subtilis str. 168 937017 NP_391579.1 CDS ywlA NC_000964.3 3795491 3795853 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3795491..3795853 Bacillus subtilis subsp. subtilis str. 168 938509 NP_391580.1 CDS ywkF NC_000964.3 3795870 3796157 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3795870..3796157) Bacillus subtilis subsp. subtilis str. 168 938510 NP_391581.1 CDS prmC NC_000964.3 3796217 3797083 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16364916; Product type e: enzyme; release factor glutamine methyltransferase complement(3796217..3797083) Bacillus subtilis subsp. subtilis str. 168 938511 NP_391582.1 CDS prfA NC_000964.3 3797085 3798155 R recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 complement(3797085..3798155) Bacillus subtilis subsp. subtilis str. 168 937031 NP_391583.1 CDS ywkD NC_000964.3 3798281 3798667 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3798281..3798667 Bacillus subtilis subsp. subtilis str. 168 937039 NP_391584.1 CDS racA NC_000964.3 3798789 3799343 D remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions; chromosome-anchoring protein RacA 3798789..3799343 Bacillus subtilis subsp. subtilis str. 168 937043 NP_391585.1 CDS ywkB NC_000964.3 3799377 3800336 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12949160, 15849754, 16850406; Product type pt: transporter; transporter complement(3799377..3800336) Bacillus subtilis subsp. subtilis str. 168 936875 NP_391586.1 CDS ywkA NC_000964.3 3800418 3802166 R malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; NAD-dependent malic enzyme 2 complement(3800418..3802166) Bacillus subtilis subsp. subtilis str. 168 937045 NP_391587.1 CDS tdk NC_000964.3 3802405 3802992 R catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase complement(3802405..3802992) Bacillus subtilis subsp. subtilis str. 168 937033 NP_391588.1 CDS rpmE NC_000964.3 3803081 3803281 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(3803081..3803281) Bacillus subtilis subsp. subtilis str. 168 937034 NP_391589.2 CDS rho NC_000964.3 3803400 3804683 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(3803400..3804683) Bacillus subtilis subsp. subtilis str. 168 937042 NP_391590.1 CDS glpX NC_000964.3 3805090 3806055 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose-1,6-bisphosphatase class 2 complement(3805090..3806055) Bacillus subtilis subsp. subtilis str. 168 937035 NP_391591.2 CDS murAB NC_000964.3 3806086 3807375 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 complement(3806086..3807375) Bacillus subtilis subsp. subtilis str. 168 937038 NP_391592.3 CDS ywjH NC_000964.3 3807754 3808392 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; transaldolase complement(3807754..3808392) Bacillus subtilis subsp. subtilis str. 168 938462 NP_391593.1 CDS fbaA NC_000964.3 3808512 3809369 R catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; fructose-bisphosphate aldolase complement(3808512..3809369) Bacillus subtilis subsp. subtilis str. 168 937040 NP_391594.1 CDS spo0F NC_000964.3 3809550 3809924 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934609, 16788205, 8257105; Product type r: regulator; sporulation initiation phosphotransferase F complement(3809550..3809924) Bacillus subtilis subsp. subtilis str. 168 937041 NP_391595.1 CDS ywjG NC_000964.3 3810090 3810611 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3810090..3810611 Bacillus subtilis subsp. subtilis str. 168 938459 NP_391596.1 CDS pyrG NC_000964.3 3810693 3812300 R CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthase complement(3810693..3812300) Bacillus subtilis subsp. subtilis str. 168 937044 NP_391597.1 CDS rpoE NC_000964.3 3812542 3813063 R participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta complement(3812542..3813063) Bacillus subtilis subsp. subtilis str. 168 937046 NP_391598.1 CDS acdA NC_000964.3 3813246 3814385 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; acyl-CoA dehydrogenase complement(3813246..3814385) Bacillus subtilis subsp. subtilis str. 168 938457 NP_391599.1 CDS fadF NC_000964.3 3814382 3816499 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17189250; Product type pe : enzyme; hypothetical protein complement(3814382..3816499) Bacillus subtilis subsp. subtilis str. 168 938461 NP_391600.1 CDS clsB NC_000964.3 3816654 3817850 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme; cardiolipin synthetase 3816654..3817850 Bacillus subtilis subsp. subtilis str. 168 938460 NP_391601.1 CDS uvsE NC_000964.3 3817863 3818825 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8614629; Product type pe : enzyme; UV DNA damage endonuclease 3817863..3818825 Bacillus subtilis subsp. subtilis str. 168 938195 NP_391602.1 CDS ywjC NC_000964.3 3818906 3819178 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3818906..3819178 Bacillus subtilis subsp. subtilis str. 168 938458 NP_391603.1 CDS ywjB NC_000964.3 3819220 3819744 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme; hypothetical protein complement(3819220..3819744) Bacillus subtilis subsp. subtilis str. 168 938455 NP_391604.1 CDS ywjA NC_000964.3 3819754 3821481 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12119303, 12354229; Product type pt: transporter; ABC transporter ATP-binding protein complement(3819754..3821481) Bacillus subtilis subsp. subtilis str. 168 937049 NP_391605.1 CDS ywiE NC_000964.3 3821570 3823072 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 15743965; Product type e: enzyme; cardiolipin synthase YwiE complement(3821570..3823072) Bacillus subtilis subsp. subtilis str. 168 938453 NP_391606.1 CDS narI NC_000964.3 3823558 3824229 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 15849754, 16850406, 7557333, 7860592, 8846791; Product type e : enzyme; nitrate reductase gamma chain complement(3823558..3824229) Bacillus subtilis subsp. subtilis str. 168 938454 NP_391607.1 CDS narJ NC_000964.3 3824226 3824780 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase molybdenum cofactor assembly chaperone NarJ complement(3824226..3824780) Bacillus subtilis subsp. subtilis str. 168 937051 NP_391608.1 CDS narH NC_000964.3 3824806 3826269 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase beta chain complement(3824806..3826269) Bacillus subtilis subsp. subtilis str. 168 937047 NP_391609.2 CDS narG NC_000964.3 3826259 3829945 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase alpha chain complement(3826259..3829945) Bacillus subtilis subsp. subtilis str. 168 938358 NP_391610.1 CDS arfM NC_000964.3 3830141 3830617 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 11698370, 16428414; Product type r: regulator; transcription regulator ArfM complement(3830141..3830617) Bacillus subtilis subsp. subtilis str. 168 937058 NP_391611.1 CDS ywiC NC_000964.3 3830761 3831480 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16428414, 16850406; Product type pm: membrane component; hypothetical protein 3830761..3831480 Bacillus subtilis subsp. subtilis str. 168 937048 NP_391612.1 CDS fnr NC_000964.3 3831512 3832228 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16796679, 8682783, 8846791; Product type r: regulator; anaerobic regulatory protein complement(3831512..3832228) Bacillus subtilis subsp. subtilis str. 168 937050 NP_391613.2 CDS narK NC_000964.3 3832327 3833514 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16796679, 16850406, 8682783, 8846791; Product type t: transporter; nitrite extrusion protein complement(3832327..3833514) Bacillus subtilis subsp. subtilis str. 168 937055 NP_391614.1 CDS argS NC_000964.3 3833650 3835320 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginine--tRNA ligase complement(3833650..3835320) Bacillus subtilis subsp. subtilis str. 168 937054 NP_391615.1 CDS ywiB NC_000964.3 3835317 3835745 R Evidence 4: Homologs of previously reported genes of unknown function; beta-barrel protein YwiB complement(3835317..3835745) Bacillus subtilis subsp. subtilis str. 168 937056 NP_391616.1 CDS sboA NC_000964.3 3836058 3836189 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12696888, 15743949, 16095584, 17213266; Product type f: factor; subtilosin-A 3836058..3836189 Bacillus subtilis subsp. subtilis str. 168 938512 YP_054594.1 CDS sboX NC_000964.3 3836146 3836298 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pf : factor; bacteriocin-like protein SboX 3836146..3836298 Bacillus subtilis subsp. subtilis str. 168 2914193 NP_391617.1 CDS albA NC_000964.3 3836323 3837669 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066831, 15743949; Product type pe: enzyme; antilisterial bacteriocin subtilosin biosynthesis protein AlbA 3836323..3837669 Bacillus subtilis subsp. subtilis str. 168 937059 NP_391618.1 CDS albB NC_000964.3 3837682 3837843 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15743949; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbB 3837682..3837843 Bacillus subtilis subsp. subtilis str. 168 937057 NP_391619.1 CDS albC NC_000964.3 3837840 3838559 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pt: transporter; ABC transporter ATP-binding protein 3837840..3838559 Bacillus subtilis subsp. subtilis str. 168 937068 NP_391620.1 CDS albD NC_000964.3 3838552 3839862 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949, 15849754, 16850406; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbD 3838552..3839862 Bacillus subtilis subsp. subtilis str. 168 937053 NP_391621.1 CDS albE NC_000964.3 3839852 3841012 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme; antilisterial bacteriocin subtilosin biosynthesis protein AlbE 3839852..3841012 Bacillus subtilis subsp. subtilis str. 168 938514 NP_391622.1 CDS albF NC_000964.3 3841017 3842297 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme; zinc protease AlbF 3841017..3842297 Bacillus subtilis subsp. subtilis str. 168 938515 NP_391623.1 CDS albG NC_000964.3 3842294 3842995 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15849754, 16850406; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbG 3842294..3842995 Bacillus subtilis subsp. subtilis str. 168 937060 NP_391624.1 CDS ywhL NC_000964.3 3843001 3844377 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3843001..3844377) Bacillus subtilis subsp. subtilis str. 168 937067 NP_391625.1 CDS ywhK NC_000964.3 3844416 3845771 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073041; Product type f: factor; hypothetical protein complement(3844416..3845771) Bacillus subtilis subsp. subtilis str. 168 937087 NP_391626.1 CDS rapF NC_000964.3 3846001 3847146 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type e: enzyme; response regulator aspartate phosphatase F 3846001..3847146 Bacillus subtilis subsp. subtilis str. 168 936725 NP_391627.1 CDS phrF NC_000964.3 3847130 3847249 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type f: factor; phosphatase RapF inhibitor 3847130..3847249 Bacillus subtilis subsp. subtilis str. 168 936721 NP_391628.1 CDS ywhH NC_000964.3 3847348 3847821 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3847348..3847821 Bacillus subtilis subsp. subtilis str. 168 937183 NP_391629.1 CDS speB NC_000964.3 3847853 3848725 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931887, 9723923; Product type e: enzyme; agmatinase complement(3847853..3848725) Bacillus subtilis subsp. subtilis str. 168 937205 NP_391630.1 CDS speE NC_000964.3 3848786 3849616 R catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase complement(3848786..3849616) Bacillus subtilis subsp. subtilis str. 168 937075 NP_391631.2 CDS pbpG NC_000964.3 3849818 3851893 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10767540, 11567005; Product type cp: cell process; penicillin-binding protein 2D 3849818..3851893 Bacillus subtilis subsp. subtilis str. 168 937200 NP_391632.1 CDS ywhD NC_000964.3 3852186 3852704 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3852186..3852704) Bacillus subtilis subsp. subtilis str. 168 937100 NP_391633.1 CDS ywhC NC_000964.3 3852718 3853377 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; zinc metalloprotease YwhC complement(3852718..3853377) Bacillus subtilis subsp. subtilis str. 168 937099 NP_391634.1 CDS ywhB NC_000964.3 3853486 3853674 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14624569, 14730980, 15301547, 17902707; Product type e: enzyme; 4-oxalocrotonate tautomerase 3853486..3853674 Bacillus subtilis subsp. subtilis str. 168 937098 NP_391635.1 CDS ywhA NC_000964.3 3853717 3854136 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwhA complement(3853717..3854136) Bacillus subtilis subsp. subtilis str. 168 937081 NP_391636.2 CDS thrZ NC_000964.3 3854256 3856172 R catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins; threonine--tRNA ligase 2 complement(3854256..3856172) Bacillus subtilis subsp. subtilis str. 168 937135 NP_391637.1 CDS mmr NC_000964.3 3857017 3858417 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11104814, 15849754, 16850406; Product type t: transporter; methylenomycin A resistance protein complement(3857017..3858417) Bacillus subtilis subsp. subtilis str. 168 937101 NP_391638.1 CDS ywgB NC_000964.3 3858417 3858887 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885456; Product type pr : regulator; HTH-type transcriptional regulator YwgB complement(3858417..3858887) Bacillus subtilis subsp. subtilis str. 168 937074 NP_391639.1 CDS ywgA NC_000964.3 3858999 3859499 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250; hypothetical protein complement(3858999..3859499) Bacillus subtilis subsp. subtilis str. 168 937077 NP_391640.1 CDS ywfO NC_000964.3 3859535 3860836 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16855250; Product type pe : enzyme; hypothetical protein complement(3859535..3860836) Bacillus subtilis subsp. subtilis str. 168 937082 NP_391641.1 CDS ywzC NC_000964.3 3860998 3861222 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250; hypothetical protein complement(3860998..3861222) Bacillus subtilis subsp. subtilis str. 168 937093 NP_391642.1 CDS rsfA NC_000964.3 3861437 3862213 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629188, 16497325; Product type cp: cell process; prespore-specific transcriptional regulator RsfA 3861437..3862213 Bacillus subtilis subsp. subtilis str. 168 937126 NP_391643.1 CDS ywfM NC_000964.3 3862357 3863247 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(3862357..3863247) Bacillus subtilis subsp. subtilis str. 168 937972 NP_391644.1 CDS ywfL NC_000964.3 3863415 3864260 R Evidence 4: Homologs of previously reported genes of unknown function; octanoyl-[GcvH]:protein N-octanoyltransferase complement(3863415..3864260) Bacillus subtilis subsp. subtilis str. 168 937083 NP_391645.1 CDS cysL NC_000964.3 3864309 3865208 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12169591; Product type r: regulator; HTH-type transcriptional regulator CysL complement(3864309..3865208) Bacillus subtilis subsp. subtilis str. 168 936502 NP_391646.1 CDS eutD NC_000964.3 3865355 3866326 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphate acetyltransferase complement(3865355..3866326) Bacillus subtilis subsp. subtilis str. 168 936581 NP_391647.2 CDS ywfI NC_000964.3 3866611 3867360 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317589, 16403788; Product type pe: enzyme; heme peroxidase 3866611..3867360 Bacillus subtilis subsp. subtilis str. 168 936512 NP_391648.1 CDS ywfH NC_000964.3 3867493 3868272 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825; Product type e: enzyme; bacilysin biosynthesis oxidoreductase YwfH 3867493..3868272 Bacillus subtilis subsp. subtilis str. 168 937215 NP_391649.1 CDS ywfG NC_000964.3 3868287 3869486 R produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; aspartate aminotransferase complement(3868287..3869486) Bacillus subtilis subsp. subtilis str. 168 937157 NP_391650.1 CDS bacE NC_000964.3 3869487 3870671 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023, 15849754, 16850406; Product type t: transporter; bacilysin exporter BacE complement(3869487..3870671) Bacillus subtilis subsp. subtilis str. 168 937161 NP_391651.1 CDS bacD NC_000964.3 3870668 3872086 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15609023, 16030213; Product type e: enzyme; alanine-anticapsin ligase BacD complement(3870668..3872086) Bacillus subtilis subsp. subtilis str. 168 937214 NP_391652.1 CDS bacC NC_000964.3 3872105 3872872 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme; bacilysin biosynthesis oxidoreductase complement(3872105..3872872) Bacillus subtilis subsp. subtilis str. 168 937065 NP_391653.1 CDS bacB NC_000964.3 3872869 3873576 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 14697267, 15609023, 15628860; Product type e: enzyme; bacilysin biosynthesis protein BacB complement(3872869..3873576) Bacillus subtilis subsp. subtilis str. 168 937084 NP_391654.1 CDS bacA NC_000964.3 3873566 3874180 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme; bacilysin biosynthesis protein BacA complement(3873566..3874180) Bacillus subtilis subsp. subtilis str. 168 937216 NP_391655.1 CDS ywfA NC_000964.3 3874332 3875570 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15609023, 15849754, 16850406; Product type pt: transporter; MFS transporter complement(3874332..3875570) Bacillus subtilis subsp. subtilis str. 168 937061 NP_391656.1 CDS rocC NC_000964.3 3875780 3877192 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7540694, 8113162; Product type t: transporter; amino acid permease RocC complement(3875780..3877192) Bacillus subtilis subsp. subtilis str. 168 938495 NP_391657.1 CDS rocB NC_000964.3 3877192 3878892 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8113162; Product type pe : enzyme; arginine utilization protein RocB complement(3877192..3878892) Bacillus subtilis subsp. subtilis str. 168 937220 NP_391658.1 CDS rocA NC_000964.3 3878966 3880513 R catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase complement(3878966..3880513) Bacillus subtilis subsp. subtilis str. 168 937222 NP_391659.2 CDS rocG NC_000964.3 3880740 3882014 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10468601, 12634342, 15150224, 17183217, 17608797, 18326565; Product type e : enzyme; catabolic NAD-specific glutamate dehydrogenase RocG complement(3880740..3882014) Bacillus subtilis subsp. subtilis str. 168 937066 NP_391660.1 CDS yweA NC_000964.3 3882191 3882655 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182; Product type ph: phenotype; hypothetical protein complement(3882191..3882655) Bacillus subtilis subsp. subtilis str. 168 937223 YP_054595.1 CDS spsL NC_000964.3 3882979 3883434 R Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; spore coat polysaccharide biosynthesis protein SpsL complement(3882979..3883434) Bacillus subtilis subsp. subtilis str. 168 2914201 NP_391661.3 CDS spsK NC_000964.3 3883427 3884278 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process; spore coat polysaccharide biosynthesis protein SpsK complement(3883427..3884278) Bacillus subtilis subsp. subtilis str. 168 937225 NP_391662.1 CDS spsJ NC_000964.3 3884292 3885239 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; dTDP-glucose 4,6-dehydratase complement(3884292..3885239) Bacillus subtilis subsp. subtilis str. 168 937227 NP_391663.1 CDS spsI NC_000964.3 3885239 3885979 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; dTDP-glucose pyrophosphorylase complement(3885239..3885979) Bacillus subtilis subsp. subtilis str. 168 937229 NP_391664.1 CDS spsG NC_000964.3 3886004 3887023 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsG complement(3886004..3887023) Bacillus subtilis subsp. subtilis str. 168 937230 NP_391665.2 CDS spsF NC_000964.3 3887026 3887748 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsF complement(3887026..3887748) Bacillus subtilis subsp. subtilis str. 168 937232 NP_391666.1 CDS spsE NC_000964.3 3887741 3888862 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001; Product type pe : enzyme; spore coat polysaccharide biosynthesis protein SpsE complement(3887741..3888862) Bacillus subtilis subsp. subtilis str. 168 937233 NP_391667.1 CDS spsD NC_000964.3 3888862 3889731 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsD complement(3888862..3889731) Bacillus subtilis subsp. subtilis str. 168 937250 NP_391668.1 CDS spsC NC_000964.3 3889732 3890901 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14602648; Product type pe : enzyme; spore coat polysaccharide biosynthesis protein SpsC complement(3889732..3890901) Bacillus subtilis subsp. subtilis str. 168 937234 NP_391669.2 CDS spsB NC_000964.3 3890922 3892346 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsB complement(3890922..3892346) Bacillus subtilis subsp. subtilis str. 168 937239 NP_391670.1 CDS spsA NC_000964.3 3892351 3893121 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10350455, 11042447, 11733986; Product type e: enzyme; spore coat polysaccharide biosynthesis protein SpsA complement(3892351..3893121) Bacillus subtilis subsp. subtilis str. 168 937253 NP_391671.1 CDS ywdL NC_000964.3 3893441 3893986 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12644503; Product type cp: cell process; spore coat protein GerQ 3893441..3893986 Bacillus subtilis subsp. subtilis str. 168 937241 NP_391672.2 CDS ywdK NC_000964.3 3894030 3894401 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3894030..3894401) Bacillus subtilis subsp. subtilis str. 168 937242 NP_391673.2 CDS ywdJ NC_000964.3 3894463 3895785 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; purine permease YwdJ complement(3894463..3895785) Bacillus subtilis subsp. subtilis str. 168 937261 NP_391674.2 CDS ywdI NC_000964.3 3895805 3896161 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3895805..3896161) Bacillus subtilis subsp. subtilis str. 168 937251 NP_391675.2 CDS ywdH NC_000964.3 3896290 3897660 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase YwdH 3896290..3897660 Bacillus subtilis subsp. subtilis str. 168 937252 NP_391676.1 CDS ung NC_000964.3 3897685 3898362 R Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase complement(3897685..3898362) Bacillus subtilis subsp. subtilis str. 168 937265 NP_391677.1 CDS ywdF NC_000964.3 3898376 3899182 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YwdF complement(3898376..3899182) Bacillus subtilis subsp. subtilis str. 168 937259 NP_391678.1 CDS ywdE NC_000964.3 3899272 3899805 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3899272..3899805) Bacillus subtilis subsp. subtilis str. 168 937260 NP_391679.2 CDS ywdD NC_000964.3 3899853 3900488 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3899853..3900488) Bacillus subtilis subsp. subtilis str. 168 937267 YP_003097793.1 CDS ywzG NC_000964.3 3900481 3900819 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; DNA-binding protein YwzG complement(3900481..3900819) Bacillus subtilis subsp. subtilis str. 168 8303176 NP_391681.1 CDS thiD NC_000964.3 3900963 3901778 D catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; pyridoxine kinase 3900963..3901778 Bacillus subtilis subsp. subtilis str. 168 937262 NP_391682.1 CDS ywdA NC_000964.3 3901868 3902116 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3901868..3902116) Bacillus subtilis subsp. subtilis str. 168 937276 NP_391683.2 CDS sacA NC_000964.3 3902210 3903649 R Evidence 2b: Function of strongly homologous gene; PubMedId: 3100393; Product type e: enzyme; sucrose-6-phosphate hydrolase complement(3902210..3903649) Bacillus subtilis subsp. subtilis str. 168 937277 NP_391684.3 CDS sacP NC_000964.3 3903646 3905031 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 15849754, 16850406, 3122206; Product type t: transporter; PTS system sucrose-specific EIIBC component complement(3903646..3905031) Bacillus subtilis subsp. subtilis str. 168 937266 NP_391685.1 CDS ywcJ NC_000964.3 3905333 3906103 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16207915, 16428414, 16850406; Product type t: transporter; transporter 3905333..3906103 Bacillus subtilis subsp. subtilis str. 168 937283 NP_391686.1 CDS sacT NC_000964.3 3906142 3906972 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 2163394, 8535520, 8702561; Product type r: regulator; SacPA operon antiterminator complement(3906142..3906972) Bacillus subtilis subsp. subtilis str. 168 937284 NP_391687.2 CDS ywcI NC_000964.3 3907012 3907314 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3907012..3907314) Bacillus subtilis subsp. subtilis str. 168 937275 NP_391688.1 CDS vpr NC_000964.3 3907844 3910264 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15596354, 16946274, 17666034; Product type e: enzyme; minor extracellular protease vpr 3907844..3910264 Bacillus subtilis subsp. subtilis str. 168 937291 NP_391689.1 CDS ywcH NC_000964.3 3910302 3911303 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913069, 15774866; Product type pe: enzyme; hypothetical protein complement(3910302..3911303) Bacillus subtilis subsp. subtilis str. 168 937286 NP_391690.1 CDS nfrA NC_000964.3 3911477 3912226 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913069, 15774866, 9535080; Product type e: enzyme; FMN reductase complement(3911477..3912226) Bacillus subtilis subsp. subtilis str. 168 937279 NP_391691.1 CDS rodA NC_000964.3 3912332 3913513 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15612918, 15849754, 16850406, 9622350; Product type f: factor; rod shape-determining protein RodA complement(3912332..3913513) Bacillus subtilis subsp. subtilis str. 168 937294 NP_391692.1 CDS ywcE NC_000964.3 3914009 3914272 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159778; Product type f: factor; spore morphogenesis and germination protein YwcE 3914009..3914272 Bacillus subtilis subsp. subtilis str. 168 937296 NP_391693.1 CDS qoxD NC_000964.3 3914315 3914689 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme; quinol oxidase subunit 4 complement(3914315..3914689) Bacillus subtilis subsp. subtilis str. 168 937285 NP_391694.1 CDS qoxC NC_000964.3 3914691 3915305 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme; quinol oxidase subunit 3 complement(3914691..3915305) Bacillus subtilis subsp. subtilis str. 168 937299 NP_391695.1 CDS qoxB NC_000964.3 3915319 3917268 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098; Product type e : enzyme; quinol oxidase subunit 1 complement(3915319..3917268) Bacillus subtilis subsp. subtilis str. 168 937303 NP_391696.2 CDS qoxA NC_000964.3 3917296 3918261 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 7495838, 7575098; Product type e: enzyme; quinol oxidase subunit 2 complement(3917296..3918261) Bacillus subtilis subsp. subtilis str. 168 937295 NP_391697.2 CDS ywzA NC_000964.3 3918777 3919022 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3918777..3919022 Bacillus subtilis subsp. subtilis str. 168 937305 NP_391698.2 CDS galT NC_000964.3 3919093 3920634 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(3919093..3920634) Bacillus subtilis subsp. subtilis str. 168 937307 NP_391699.1 CDS galK NC_000964.3 3920638 3921810 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(3920638..3921810) Bacillus subtilis subsp. subtilis str. 168 937297 NP_391700.1 CDS ywcD NC_000964.3 3921891 3922274 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein complement(3921891..3922274) Bacillus subtilis subsp. subtilis str. 168 937313 NP_391701.2 CDS ywcC NC_000964.3 3922292 3922963 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwcC complement(3922292..3922963) Bacillus subtilis subsp. subtilis str. 168 937314 YP_003097794.1 CDS slrA NC_000964.3 3923319 3923477 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18647168; Product type r: regulator; transcriptional regulator SlrA 3923319..3923477 Bacillus subtilis subsp. subtilis str. 168 8303165 NP_391702.1 CDS ywcB NC_000964.3 3923920 3924228 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 3923920..3924228 Bacillus subtilis subsp. subtilis str. 168 937304 NP_391703.2 CDS ywcA NC_000964.3 3924225 3925766 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; symporter 3924225..3925766 Bacillus subtilis subsp. subtilis str. 168 937320 NP_391704.1 CDS ywbO NC_000964.3 3925797 3926399 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(3925797..3926399) Bacillus subtilis subsp. subtilis str. 168 937309 NP_391705.1 CDS efeN NC_000964.3 3926682 3927932 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15554971, 16672620, 16987175, 18931290; Product type e: enzyme; deferrochelatase/peroxidase EfeN complement(3926682..3927932) Bacillus subtilis subsp. subtilis str. 168 937310 NP_391706.1 CDS efeM NC_000964.3 3927951 3929108 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 16987175; Product type t: transporter; iron uptake system component EfeM complement(3927951..3929108) Bacillus subtilis subsp. subtilis str. 168 937322 NP_391707.2 CDS efeU NC_000964.3 3929105 3930550 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 16987175; Product type t : transporter; ferrous iron permease EfeU complement(3929105..3930550) Bacillus subtilis subsp. subtilis str. 168 938520 NP_391708.1 CDS thiE NC_000964.3 3930707 3931375 R Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate synthase complement(3930707..3931375) Bacillus subtilis subsp. subtilis str. 168 937316 NP_391709.1 CDS thiM NC_000964.3 3931372 3932190 R catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase complement(3931372..3932190) Bacillus subtilis subsp. subtilis str. 168 938519 NP_391710.1 CDS ywbI NC_000964.3 3932198 3933103 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwbI complement(3932198..3933103) Bacillus subtilis subsp. subtilis str. 168 937626 NP_391711.1 CDS ywbH NC_000964.3 3933209 3933595 D increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB; holin-like protein CidA 3933209..3933595 Bacillus subtilis subsp. subtilis str. 168 937321 NP_391712.2 CDS lrgB NC_000964.3 3933577 3934254 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15659658, 15849754, 16850406; Product type r : regulator; hypothetical protein 3933577..3934254 Bacillus subtilis subsp. subtilis str. 168 937323 NP_391713.1 CDS ywbF NC_000964.3 3934358 3935557 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3934358..3935557 Bacillus subtilis subsp. subtilis str. 168 937325 NP_391714.1 CDS ywbE NC_000964.3 3935591 3935788 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3935591..3935788 Bacillus subtilis subsp. subtilis str. 168 937326 NP_391715.1 CDS ywbD NC_000964.3 3935824 3937014 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ribosomal RNA large subunit methyltransferase YwbD complement(3935824..3937014) Bacillus subtilis subsp. subtilis str. 168 937328 NP_391716.1 CDS ywbC NC_000964.3 3937135 3937515 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3937135..3937515 Bacillus subtilis subsp. subtilis str. 168 937329 NP_391717.1 CDS ywbB NC_000964.3 3937553 3938230 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(3937553..3938230) Bacillus subtilis subsp. subtilis str. 168 937330 NP_391718.1 CDS ywbA NC_000964.3 3938307 3939641 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 8990303; Product type pt: transporter; permease IIC component YwbA complement(3938307..3939641) Bacillus subtilis subsp. subtilis str. 168 937331 NP_391719.1 CDS epr NC_000964.3 3939869 3941806 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553828, 17666034, 1938892, 2116590; Product type e: enzyme; minor extracellular protease epr 3939869..3941806 Bacillus subtilis subsp. subtilis str. 168 937332 NP_391720.1 CDS sacX NC_000964.3 3942234 3943613 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 1400159, 15849754, 16850406, 8535520; Product type r: regulator; negative regulator of SacY activity 3942234..3943613 Bacillus subtilis subsp. subtilis str. 168 937333 NP_391721.1 CDS sacY NC_000964.3 3943667 3944509 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 12079345, 15528654, 9305644, 9457872; Product type r: regulator; levansucrase and sucrase synthesis operon antiterminator 3943667..3944509 Bacillus subtilis subsp. subtilis str. 168 937335 NP_391722.1 CDS gspA NC_000964.3 3944560 3945420 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11377871; Product type pe : enzyme; general stress protein A complement(3944560..3945420) Bacillus subtilis subsp. subtilis str. 168 937339 NP_391723.1 CDS ywaF NC_000964.3 3945530 3946243 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(3945530..3946243) Bacillus subtilis subsp. subtilis str. 168 937341 NP_391724.1 CDS ywaE NC_000964.3 3946394 3946909 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwaE 3946394..3946909 Bacillus subtilis subsp. subtilis str. 168 937344 NP_391725.1 CDS tyrZ NC_000964.3 3947158 3948399 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosine--tRNA ligase 2 3947158..3948399 Bacillus subtilis subsp. subtilis str. 168 937345 NP_391726.1 CDS ywaD NC_000964.3 3948555 3949922 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668014; Product type e: enzyme; aminopeptidase YwaD 3948555..3949922 Bacillus subtilis subsp. subtilis str. 168 937350 NP_391727.1 CDS ywaC NC_000964.3 3949952 3950584 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17114254, 18067544; Product type e: enzyme; GTP pyrophosphokinase YwaC complement(3949952..3950584) Bacillus subtilis subsp. subtilis str. 168 937355 NP_391728.1 CDS menA NC_000964.3 3950726 3951661 R catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase complement(3950726..3951661) Bacillus subtilis subsp. subtilis str. 168 937356 YP_003097795.1 CDS ywzH NC_000964.3 3952108 3952257 D Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3952108..3952257 Bacillus subtilis subsp. subtilis str. 168 8303014 NP_391729.1 CDS dltA NC_000964.3 3952275 3953786 D transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 3952275..3953786 Bacillus subtilis subsp. subtilis str. 168 937358 NP_391730.1 CDS dltB NC_000964.3 3953783 3954970 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 15849754, 16850406, 17263852; Product type e : enzyme; protein DltB 3953783..3954970 Bacillus subtilis subsp. subtilis str. 168 937360 NP_391731.1 CDS dltC NC_000964.3 3954987 3955223 D D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 3954987..3955223 Bacillus subtilis subsp. subtilis str. 168 937361 NP_391732.1 CDS dltD NC_000964.3 3955223 3956401 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 17263852; Product type pe: enzyme; poly D-alanine transfer protein DltD 3955223..3956401 Bacillus subtilis subsp. subtilis str. 168 937362 NP_391733.2 CDS dltE NC_000964.3 3956492 3957250 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14665680, 7797557; Product type pe: enzyme; oxidoreductase 3956492..3957250 Bacillus subtilis subsp. subtilis str. 168 937369 NP_391734.2 CDS ywaA NC_000964.3 3957391 3958482 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain-amino acid aminotransferase 2 3957391..3958482 Bacillus subtilis subsp. subtilis str. 168 937372 NP_391735.1 CDS licH NC_000964.3 3958516 3959844 R Evidence 2b: Function of strongly homologous gene; PubMedId: 8990303; Product type e: enzyme; 6-phospho-beta-glucosidase complement(3958516..3959844) Bacillus subtilis subsp. subtilis str. 168 937373 NP_391736.1 CDS licA NC_000964.3 3959841 3960173 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303; Product type t: transporter; PTS system lichenan transporter subunit IIA complement(3959841..3960173) Bacillus subtilis subsp. subtilis str. 168 937374 NP_391737.1 CDS licC NC_000964.3 3960192 3961550 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 15849754, 16850406; Product type t: transporter; PTS system lichenan transporter subunit IIC complement(3960192..3961550) Bacillus subtilis subsp. subtilis str. 168 937375 NP_391738.1 CDS licB NC_000964.3 3961566 3961874 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772; Product type t: transporter; PTS system lichenan transporter subunit IIB complement(3961566..3961874) Bacillus subtilis subsp. subtilis str. 168 937379 NP_391739.1 CDS licR NC_000964.3 3962003 3963928 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303, 9353933; Product type r: regulator; licABCH operon regulator complement(3962003..3963928) Bacillus subtilis subsp. subtilis str. 168 937383 NP_391740.1 CDS yxzF NC_000964.3 3964091 3964249 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(3964091..3964249) Bacillus subtilis subsp. subtilis str. 168 937390 NP_391741.1 CDS yxlJ NC_000964.3 3964278 3964868 R responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase complement(3964278..3964868) Bacillus subtilis subsp. subtilis str. 168 937391 NP_391742.1 CDS katX NC_000964.3 3964997 3966640 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10503549, 9393707, 9555886; Product type e: enzyme; catalase X 3964997..3966640 Bacillus subtilis subsp. subtilis str. 168 937399 NP_391743.1 CDS yxlH NC_000964.3 3966745 3967947 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3966745..3967947 Bacillus subtilis subsp. subtilis str. 168 937392 NP_391744.2 CDS yxlG NC_000964.3 3967944 3968720 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14769884, 15849754, 16850406; Product type pt: transporter; transmembrane protein YxlG complement(3967944..3968720) Bacillus subtilis subsp. subtilis str. 168 937394 NP_391745.1 CDS yxlF NC_000964.3 3968717 3969604 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pt: transporter; ABC transporter ATP-binding protein complement(3968717..3969604) Bacillus subtilis subsp. subtilis str. 168 938137 NP_391746.1 CDS yxlE NC_000964.3 3969611 3969799 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator; negative regulatory protein YxlE complement(3969611..3969799) Bacillus subtilis subsp. subtilis str. 168 937395 NP_391747.1 CDS yxlD NC_000964.3 3969796 3970002 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pr: regulator; negative regulatory protein YxlD complement(3969796..3970002) Bacillus subtilis subsp. subtilis str. 168 937398 NP_391748.1 CDS yxlC NC_000964.3 3969999 3970319 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator; hypothetical protein complement(3969999..3970319) Bacillus subtilis subsp. subtilis str. 168 938082 NP_391749.1 CDS sigY NC_000964.3 3970312 3970848 R Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigY complement(3970312..3970848) Bacillus subtilis subsp. subtilis str. 168 937400 NP_391750.1 CDS yxlA NC_000964.3 3971060 3972433 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 2191181; Product type pt: transporter; purine-cytosine permease YxlA 3971060..3972433 Bacillus subtilis subsp. subtilis str. 168 937405 NP_391751.1 CDS yxkO NC_000964.3 3972448 3973278 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12457846; Product type pe : enzyme; adp-dependent (S)-NAD(P)H-hydrate dehydratase complement(3972448..3973278) Bacillus subtilis subsp. subtilis str. 168 937408 NP_391752.1 CDS cydD NC_000964.3 3973364 3975091 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter; ATP-binding/permease protein CydD complement(3973364..3975091) Bacillus subtilis subsp. subtilis str. 168 936330 NP_391753.1 CDS cydC NC_000964.3 3975088 3976791 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter; ATP-binding/permease protein CydC complement(3975088..3976791) Bacillus subtilis subsp. subtilis str. 168 936498 NP_391754.1 CDS cydB NC_000964.3 3976791 3977807 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme; cytochrome d ubiquinol oxidase subunit 2 complement(3976791..3977807) Bacillus subtilis subsp. subtilis str. 168 937412 NP_391755.1 CDS cydA NC_000964.3 3977791 3979197 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme; cytochrome d ubiquinol oxidase subunit 1 complement(3977791..3979197) Bacillus subtilis subsp. subtilis str. 168 937406 NP_391756.1 CDS cimH NC_000964.3 3979753 3981105 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566984, 15849754, 16850406; Product type t: transporter; citrate/malate transporter 3979753..3981105 Bacillus subtilis subsp. subtilis str. 168 937407 NP_391757.1 CDS yxkI NC_000964.3 3981227 3982915 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pe : enzyme; membrane metalloprotease YxkI 3981227..3982915 Bacillus subtilis subsp. subtilis str. 168 937415 NP_391758.1 CDS yxzE NC_000964.3 3982973 3983173 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; hypothetical protein 3982973..3983173 Bacillus subtilis subsp. subtilis str. 168 937409 NP_391759.1 CDS yxkH NC_000964.3 3983187 3984026 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polysaccharide deacetylase complement(3983187..3984026) Bacillus subtilis subsp. subtilis str. 168 937411 NP_391760.1 CDS msmX NC_000964.3 3984133 3985230 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter; maltodextrin import ATP-binding protein MsmX complement(3984133..3985230) Bacillus subtilis subsp. subtilis str. 168 937422 NP_391761.1 CDS yxkF NC_000964.3 3985351 3986244 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pr : regulator; hypothetical protein complement(3985351..3986244) Bacillus subtilis subsp. subtilis str. 168 937413 NP_391762.1 CDS aldY NC_000964.3 3986428 3987885 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; aldehyde dehydrogenase AldY 3986428..3987885 Bacillus subtilis subsp. subtilis str. 168 937414 NP_391763.1 CDS yxkD NC_000964.3 3987927 3988763 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624, 15849754, 16850406; Product type t : transporter; hypothetical protein complement(3987927..3988763) Bacillus subtilis subsp. subtilis str. 168 937425 NP_391764.1 CDS yxkC NC_000964.3 3989232 3989873 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818, 15033535; hypothetical protein 3989232..3989873 Bacillus subtilis subsp. subtilis str. 168 937416 NP_391765.1 CDS galE NC_000964.3 3989948 3990967 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14597172, 9555917; Product type e: enzyme; UDP-glucose 4-epimerase complement(3989948..3990967) Bacillus subtilis subsp. subtilis str. 168 937420 NP_391766.1 CDS yxkA NC_000964.3 3991082 3991588 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(3991082..3991588) Bacillus subtilis subsp. subtilis str. 168 937438 NP_391767.1 CDS yxjO NC_000964.3 3991718 3992593 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12169591; Product type pr : regulator; HTH-type transcriptional regulator YxjO 3991718..3992593 Bacillus subtilis subsp. subtilis str. 168 937423 NP_391768.1 CDS yxjN NC_000964.3 3992671 3993144 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3992671..3993144 Bacillus subtilis subsp. subtilis str. 168 937424 NP_391769.1 CDS yxjM NC_000964.3 3993162 3994382 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 3993162..3994382 Bacillus subtilis subsp. subtilis str. 168 937441 NP_391770.1 CDS yxjL NC_000964.3 3994369 3995025 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 3994369..3995025 Bacillus subtilis subsp. subtilis str. 168 937427 NP_391771.1 CDS pepT NC_000964.3 3995075 3996307 D catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 3995075..3996307 Bacillus subtilis subsp. subtilis str. 168 937428 NP_391772.1 CDS yxjJ NC_000964.3 3996829 3997092 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 3996829..3997092 Bacillus subtilis subsp. subtilis str. 168 937454 NP_391773.1 CDS yxjI NC_000964.3 3997221 3997709 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3997221..3997709 Bacillus subtilis subsp. subtilis str. 168 937439 NP_391774.2 CDS yxjH NC_000964.3 3997964 3999097 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320, 17098890; Product type pe: enzyme; hypothetical protein 3997964..3999097 Bacillus subtilis subsp. subtilis str. 168 937440 NP_391775.3 CDS yxjG NC_000964.3 3999350 4000486 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320; Product type pe : enzyme; hypothetical protein 3999350..4000486 Bacillus subtilis subsp. subtilis str. 168 937457 NP_391776.2 CDS yxjF NC_000964.3 4000539 4001312 R catalyzes the formation of acetoacetate from 3-hydroxybutyrate; oxidoreductase complement(4000539..4001312) Bacillus subtilis subsp. subtilis str. 168 937450 NP_391777.1 CDS scoB NC_000964.3 4001329 4001979 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme; succinyl-CoA:3-ketoacid coenzyme A transferase subunit B complement(4001329..4001979) Bacillus subtilis subsp. subtilis str. 168 937453 NP_391778.1 CDS scoA NC_000964.3 4001976 4002692 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme; succinyl-CoA:3-ketoacid coenzyme A transferase subunit A complement(4001976..4002692) Bacillus subtilis subsp. subtilis str. 168 937468 NP_391779.3 CDS yxjC NC_000964.3 4002716 4004134 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(4002716..4004134) Bacillus subtilis subsp. subtilis str. 168 937455 NP_391780.1 CDS yxjB NC_000964.3 4004288 4005136 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 23S rRNA (guanine-N(1)-)-methyltransferase YxjB complement(4004288..4005136) Bacillus subtilis subsp. subtilis str. 168 937456 NP_391781.2 CDS yxjA NC_000964.3 4005752 4006945 D Evidence 2b: Function of strongly homologous gene; PubMedId: 12787499, 15849754, 16850406; Product type t: transporter; purine nucleoside transport protein NupG 4005752..4006945 Bacillus subtilis subsp. subtilis str. 168 937472 NP_391783.2 CDS yxiS NC_000964.3 4007803 4008093 R Evidence 7: Gene remnant; hypothetical protein complement(4007803..4008093) Bacillus subtilis subsp. subtilis str. 168 937467 NP_391784.2 CDS katE NC_000964.3 4008143 4010203 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16151211, 7559348, 8931328; Product type e: enzyme; catalase-2 complement(4008143..4010203) Bacillus subtilis subsp. subtilis str. 168 937481 NP_391785.2 CDS citH NC_000964.3 4010404 4011684 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11053381, 15849754, 16850406, 8892821; Product type t: transporter; citrate transporter 4010404..4011684 Bacillus subtilis subsp. subtilis str. 168 937469 NP_391786.1 CDS bglS NC_000964.3 4011842 4012570 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1369198, 3106158, 7704256; Product type e: enzyme; beta-glucanase complement(4011842..4012570) Bacillus subtilis subsp. subtilis str. 168 937470 NP_391787.2 CDS licT NC_000964.3 4012866 4013699 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11447120, 11580842, 11733988, 12169607, 15699035; Product type r: regulator; transcription antiterminator LicT complement(4012866..4013699) Bacillus subtilis subsp. subtilis str. 168 937503 NP_391788.1 CDS yxiP NC_000964.3 4013795 4014475 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein complement(4013795..4014475) Bacillus subtilis subsp. subtilis str. 168 937473 NP_391789.1 CDS yxiO NC_000964.3 4014682 4015968 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12583894, 15849754, 16850406; Product type pt: transporter; MFS transporter 4014682..4015968 Bacillus subtilis subsp. subtilis str. 168 937480 NP_391790.2 CDS deaD NC_000964.3 4015987 4017426 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10481020, 16118224, 16611943, 17142894, 17229151, 17951299; Product type e : enzyme; ATP-dependent RNA helicase DbpA complement(4015987..4017426) Bacillus subtilis subsp. subtilis str. 168 937492 NP_391791.2 CDS yxiM NC_000964.3 4017508 4018656 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pe : enzyme; esterase YxiM complement(4017508..4018656) Bacillus subtilis subsp. subtilis str. 168 937485 YP_003097796.1 CDS yxzJ NC_000964.3 4019005 4019136 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4019005..4019136) Bacillus subtilis subsp. subtilis str. 168 8303069 NP_391793.1 CDS yxiK NC_000964.3 4019148 4019609 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(4019148..4019609) Bacillus subtilis subsp. subtilis str. 168 937483 NP_391794.1 CDS yxiJ NC_000964.3 4019625 4019921 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4019625..4019921) Bacillus subtilis subsp. subtilis str. 168 937504 NP_391795.1 CDS yxiI NC_000964.3 4019949 4020437 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4019949..4020437) Bacillus subtilis subsp. subtilis str. 168 937495 NP_391796.1 CDS yxzG NC_000964.3 4020455 4020907 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(4020455..4020907) Bacillus subtilis subsp. subtilis str. 168 937507 NP_391797.1 CDS yxiH NC_000964.3 4020977 4021306 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4020977..4021306) Bacillus subtilis subsp. subtilis str. 168 937476 NP_391798.1 CDS yxiG NC_000964.3 4021429 4021845 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4021429..4021845) Bacillus subtilis subsp. subtilis str. 168 937774 NP_391799.1 CDS yxzC NC_000964.3 4021896 4022264 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein complement(4021896..4022264) Bacillus subtilis subsp. subtilis str. 168 937967 NP_391800.1 CDS yxiF NC_000964.3 4022258 4022728 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4022258..4022728) Bacillus subtilis subsp. subtilis str. 168 937519 NP_391801.1 CDS yxxG NC_000964.3 4023054 4023482 R Evidence 5: No homology to any previously reported sequences; PubMedId: 1529529, 16306698; hypothetical protein complement(4023054..4023482) Bacillus subtilis subsp. subtilis str. 168 937508 NP_391802.2 CDS wapA NC_000964.3 4023544 4030548 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 16849803, 9537385; Product type f: factor; wall-associated protein complement(4023544..4030548) Bacillus subtilis subsp. subtilis str. 168 937525 NP_391803.1 CDS yxxF NC_000964.3 4030710 4031645 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter complement(4030710..4031645) Bacillus subtilis subsp. subtilis str. 168 937510 NP_391804.1 CDS yxiE NC_000964.3 4031797 4032243 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12644671, 17210127; Product type f: factor; universal stress protein YxiE complement(4031797..4032243) Bacillus subtilis subsp. subtilis str. 168 937971 NP_391805.2 CDS bglH NC_000964.3 4032346 4033755 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglH complement(4032346..4033755) Bacillus subtilis subsp. subtilis str. 168 937512 NP_391806.2 CDS bglP NC_000964.3 4033778 4035607 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17074746, 8626332; Product type t: transporter; PTS system beta-glucoside-specific EIIBCA component complement(4033778..4035607) Bacillus subtilis subsp. subtilis str. 168 937518 NP_391807.1 CDS yxxE NC_000964.3 4035990 4036298 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4035990..4036298) Bacillus subtilis subsp. subtilis str. 168 937520 NP_391808.1 CDS yxxD NC_000964.3 4036344 4036787 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4036344..4036787) Bacillus subtilis subsp. subtilis str. 168 937530 NP_391809.2 CDS yxiD NC_000964.3 4036784 4038493 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein complement(4036784..4038493) Bacillus subtilis subsp. subtilis str. 168 937523 NP_391810.1 CDS yxiC NC_000964.3 4038513 4038782 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4038513..4038782) Bacillus subtilis subsp. subtilis str. 168 937521 NP_391811.1 CDS yxiB NC_000964.3 4038794 4039159 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4038794..4039159) Bacillus subtilis subsp. subtilis str. 168 937532 NP_391812.2 CDS abnB NC_000964.3 4039466 4040875 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973026, 18408032; Product type e: enzyme; arabinan endo-1,5-alpha-L-arabinosidase complement(4039466..4040875) Bacillus subtilis subsp. subtilis str. 168 937533 YP_003097797.1 CDS yxzL NC_000964.3 4041009 4041173 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4041009..4041173) Bacillus subtilis subsp. subtilis str. 168 8302942 NP_391813.1 CDS hutP NC_000964.3 4041483 4041938 D regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure; anti-terminator HutP 4041483..4041938 Bacillus subtilis subsp. subtilis str. 168 937529 NP_391814.1 CDS hutH NC_000964.3 4042051 4043577 D catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 4042051..4043577 Bacillus subtilis subsp. subtilis str. 168 937541 NP_391815.1 CDS hutU NC_000964.3 4043574 4045232 D catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 4043574..4045232 Bacillus subtilis subsp. subtilis str. 168 937542 NP_391816.1 CDS hutI NC_000964.3 4045245 4046510 D catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 4045245..4046510 Bacillus subtilis subsp. subtilis str. 168 937531 NP_391817.1 CDS hutG NC_000964.3 4046503 4047462 D catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 4046503..4047462 Bacillus subtilis subsp. subtilis str. 168 937546 NP_391818.2 CDS hutM NC_000964.3 4047538 4048965 D Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 7704263; Product type t: transporter; histidine permease 4047538..4048965 Bacillus subtilis subsp. subtilis str. 168 938565 NP_391819.2 CDS pdp NC_000964.3 4049009 4050310 R Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase complement(4049009..4050310) Bacillus subtilis subsp. subtilis str. 168 937540 NP_391820.2 CDS nupC NC_000964.3 4050340 4051521 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 15849754, 16850406, 8550462; Product type t: transporter; pyrimidine nucleoside transport protein complement(4050340..4051521) Bacillus subtilis subsp. subtilis str. 168 937534 NP_391821.2 CDS deoC NC_000964.3 4051602 4052273 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 11065368, 8550462; Product type e: enzyme; deoxyribose-phosphate aldolase complement(4051602..4052273) Bacillus subtilis subsp. subtilis str. 168 938608 NP_391822.1 CDS deoR NC_000964.3 4052379 4053320 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 10714997, 8550462; Product type r: regulator; deoxyribonucleoside regulator complement(4052379..4053320) Bacillus subtilis subsp. subtilis str. 168 937543 NP_391823.2 CDS yxxB NC_000964.3 4053454 4054281 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4053454..4054281) Bacillus subtilis subsp. subtilis str. 168 937547 NP_391824.1 CDS yxeR NC_000964.3 4054354 4055466 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pt: transporter; hypothetical protein complement(4054354..4055466) Bacillus subtilis subsp. subtilis str. 168 937551 NP_391825.2 CDS yxeQ NC_000964.3 4055536 4056873 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; hypothetical protein complement(4055536..4056873) Bacillus subtilis subsp. subtilis str. 168 938528 NP_391826.2 CDS yxeP NC_000964.3 4056870 4058012 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; hydrolase YxeP complement(4056870..4058012) Bacillus subtilis subsp. subtilis str. 168 937572 NP_391827.1 CDS yxeO NC_000964.3 4058029 4058778 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pt: transporter; amino acid import ATP-binding protein YxeO complement(4058029..4058778) Bacillus subtilis subsp. subtilis str. 168 937555 NP_391828.1 CDS yxeN NC_000964.3 4058791 4059465 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 15849754, 16513748, 16850406, 16885442; Product type pt: transporter; amino acid permease protein YxeN complement(4058791..4059465) Bacillus subtilis subsp. subtilis str. 168 937554 NP_391829.1 CDS yxeM NC_000964.3 4059488 4060282 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type lp: lipoprotein; amino acid-binding protein YxeM complement(4059488..4060282) Bacillus subtilis subsp. subtilis str. 168 937568 NP_391830.2 CDS yxeL NC_000964.3 4060307 4060804 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; N-acetyltransferase YxeL complement(4060307..4060804) Bacillus subtilis subsp. subtilis str. 168 937563 NP_391831.1 CDS yxeK NC_000964.3 4060818 4062143 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; monooxygenase YxeK complement(4060818..4062143) Bacillus subtilis subsp. subtilis str. 168 937570 NP_391832.2 CDS yxeJ NC_000964.3 4062329 4062556 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4062329..4062556) Bacillus subtilis subsp. subtilis str. 168 937574 NP_391833.2 CDS yxeI NC_000964.3 4062543 4063529 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937167; Product type pe : enzyme; hypothetical protein complement(4062543..4063529) Bacillus subtilis subsp. subtilis str. 168 937573 NP_391834.1 CDS yxeH NC_000964.3 4063684 4064496 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4063684..4064496) Bacillus subtilis subsp. subtilis str. 168 937571 NP_391835.1 CDS yxeG NC_000964.3 4064536 4065093 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4064536..4065093) Bacillus subtilis subsp. subtilis str. 168 937586 NP_391836.1 CDS yxeF NC_000964.3 4065074 4065508 R Evidence 5: No homology to any previously reported sequences; PubMedId: 11160890; hypothetical protein complement(4065074..4065508) Bacillus subtilis subsp. subtilis str. 168 937562 NP_391837.1 CDS yxeE NC_000964.3 4065597 4065962 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 17905812; Product type s: structure; hypothetical protein 4065597..4065962 Bacillus subtilis subsp. subtilis str. 168 936477 NP_391838.2 CDS yxeD NC_000964.3 4066210 4066563 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4066210..4066563 Bacillus subtilis subsp. subtilis str. 168 937597 NP_391839.2 CDS yxeC NC_000964.3 4066607 4067005 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4066607..4067005) Bacillus subtilis subsp. subtilis str. 168 937578 NP_391840.2 CDS yxeB NC_000964.3 4067183 4068148 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 8388528; Product type t: transporter; iron(3+)-hydroxamate-binding protein YxeB 4067183..4068148 Bacillus subtilis subsp. subtilis str. 168 937581 NP_391841.1 CDS yxeA NC_000964.3 4068189 4068536 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4068189..4068536) Bacillus subtilis subsp. subtilis str. 168 937612 NP_391842.2 CDS yxdM NC_000964.3 4068550 4070418 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15849754, 15870467, 16850406; Product type t: transporter; ABC transporter permease complement(4068550..4070418) Bacillus subtilis subsp. subtilis str. 168 937589 NP_391843.2 CDS yxdL NC_000964.3 4070393 4071166 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15870467; Product type t: transporter; ABC transporter ATP-binding protein complement(4070393..4071166) Bacillus subtilis subsp. subtilis str. 168 937596 NP_391844.1 CDS yxdK NC_000964.3 4071310 4072287 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type e: enzyme; sensor histidine kinase complement(4071310..4072287) Bacillus subtilis subsp. subtilis str. 168 937487 NP_391845.1 CDS yxdJ NC_000964.3 4072284 4072973 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type r: regulator; transcriptional regulator complement(4072284..4072973) Bacillus subtilis subsp. subtilis str. 168 937599 NP_391846.1 CDS iolJ NC_000964.3 4073081 4073953 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658656, 11325924, 18310071, 9226270; Product type e: enzyme; 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase complement(4073081..4073953) Bacillus subtilis subsp. subtilis str. 168 937601 NP_391847.1 CDS iolI NC_000964.3 4073974 4074810 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 17619021, 9887260; Product type pe: enzyme; inosose isomerase complement(4073974..4074810) Bacillus subtilis subsp. subtilis str. 168 937582 NP_391848.1 CDS iolH NC_000964.3 4074896 4075765 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 9887260; Product type pe: enzyme; myo-inositol catabolism protein IolH complement(4074896..4075765) Bacillus subtilis subsp. subtilis str. 168 937613 NP_391849.2 CDS iolG NC_000964.3 4075785 4076819 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274120, 15678175, 9226270; Product type e: enzyme; inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase complement(4075785..4076819) Bacillus subtilis subsp. subtilis str. 168 937615 NP_391850.2 CDS iolF NC_000964.3 4076842 4078158 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter; minor myo-inositol transporter IolF complement(4076842..4078158) Bacillus subtilis subsp. subtilis str. 168 937616 NP_391851.1 CDS iolE NC_000964.3 4078173 4079066 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14993306, 9226270; Product type e: enzyme; inosose dehydratase complement(4078173..4079066) Bacillus subtilis subsp. subtilis str. 168 936212 NP_391852.2 CDS iolD NC_000964.3 4079083 4080996 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase complement(4079083..4080996) Bacillus subtilis subsp. subtilis str. 168 937590 NP_391853.1 CDS iolC NC_000964.3 4081029 4082006 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 5-dehydro-2-deoxygluconokinase complement(4081029..4082006) Bacillus subtilis subsp. subtilis str. 168 937622 NP_391854.2 CDS iolB NC_000964.3 4082030 4082845 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 5-deoxy-glucuronate isomerase complement(4082030..4082845) Bacillus subtilis subsp. subtilis str. 168 937580 NP_391855.1 CDS mmsA NC_000964.3 4082920 4084383 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658656, 11566986, 16332250; Product type e: enzyme; methylmalonate semialdehyde dehydrogenase complement(4082920..4084383) Bacillus subtilis subsp. subtilis str. 168 937575 NP_391856.1 CDS iolR NC_000964.3 4084799 4085554 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 11807058, 9887260; Product type r: regulator; HTH-type transcriptional regulator IolR 4084799..4085554 Bacillus subtilis subsp. subtilis str. 168 937635 NP_391857.1 CDS iolS NC_000964.3 4085608 4086540 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15019785, 9226270; Product type e: enzyme; aldo/keto reductase family protein IolS 4085608..4086540 Bacillus subtilis subsp. subtilis str. 168 937636 NP_391858.1 CDS yxcE NC_000964.3 4086802 4087452 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4086802..4087452 Bacillus subtilis subsp. subtilis str. 168 937621 NP_391859.1 CDS yxcD NC_000964.3 4087456 4087764 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4087456..4087764 Bacillus subtilis subsp. subtilis str. 168 937638 NP_391860.1 CDS csbC NC_000964.3 4088002 4089387 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376822, 15849754, 16850406; Product type pt: transporter; metabolite transport protein CsbC 4088002..4089387 Bacillus subtilis subsp. subtilis str. 168 937639 NP_391861.1 CDS htpG NC_000964.3 4089429 4091309 R molecular chaperone; chaperone protein HtpG complement(4089429..4091309) Bacillus subtilis subsp. subtilis str. 168 937631 NP_391862.1 CDS yxcA NC_000964.3 4091477 4091728 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4091477..4091728) Bacillus subtilis subsp. subtilis str. 168 937641 NP_391863.2 CDS yxbG NC_000964.3 4091845 4092666 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 4091845..4092666 Bacillus subtilis subsp. subtilis str. 168 937642 NP_391864.1 CDS yxbF NC_000964.3 4092695 4093837 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pr : regulator; HTH-type transcriptional regulator YxbF complement(4092695..4093837) Bacillus subtilis subsp. subtilis str. 168 937637 NP_391865.2 CDS aldX NC_000964.3 4093980 4095317 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase AldX 4093980..4095317 Bacillus subtilis subsp. subtilis str. 168 937653 NP_391866.2 CDS yxbD NC_000964.3 4095356 4095835 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4095356..4095835) Bacillus subtilis subsp. subtilis str. 168 937655 NP_391867.1 CDS yxbC NC_000964.3 4095915 4096907 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4095915..4096907) Bacillus subtilis subsp. subtilis str. 168 937640 NP_391868.1 CDS yxbB NC_000964.3 4097416 4098150 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941984; Product type pe : enzyme; hypothetical protein 4097416..4098150 Bacillus subtilis subsp. subtilis str. 168 937673 NP_391869.1 CDS aslA NC_000964.3 4098150 4098419 D Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17083466; Product type e: enzyme; hypothetical protein 4098150..4098419 Bacillus subtilis subsp. subtilis str. 168 937675 NP_391870.1 CDS yxnB NC_000964.3 4098423 4098905 D Evidence 5: No homology to any previously reported sequences; hypothetical protein 4098423..4098905 Bacillus subtilis subsp. subtilis str. 168 937643 NP_391871.2 CDS asnH NC_000964.3 4098926 4101169 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721, 17083466; Product type e: enzyme; asparagine synthetase 2 4098926..4101169 Bacillus subtilis subsp. subtilis str. 168 937677 NP_391872.2 CDS yxaM NC_000964.3 4101166 4102365 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter; MFS transporter 4101166..4102365 Bacillus subtilis subsp. subtilis str. 168 937678 NP_391873.2 CDS yxaL NC_000964.3 4102429 4103661 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 15743949; Product type e: enzyme; hypothetical protein complement(4102429..4103661) Bacillus subtilis subsp. subtilis str. 168 937661 NP_391875.2 CDS yxaJ NC_000964.3 4103762 4104187 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4103762..4104187) Bacillus subtilis subsp. subtilis str. 168 937687 NP_391876.1 CDS yxaI NC_000964.3 4104444 4104899 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4104444..4104899 Bacillus subtilis subsp. subtilis str. 168 937676 NP_391877.2 CDS yxaH NC_000964.3 4104929 4106137 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317768, 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4104929..4106137) Bacillus subtilis subsp. subtilis str. 168 937697 NP_391878.2 CDS qodI NC_000964.3 4106245 4107258 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14697267, 15317768, 15628860, 17483215; Product type e: enzyme; quercetin 2,3-dioxygenase complement(4106245..4107258) Bacillus subtilis subsp. subtilis str. 168 937689 NP_391879.2 CDS yxaF NC_000964.3 4107352 4107927 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483215; Product type r: regulator; HTH-type transcriptional regulator YxaF complement(4107352..4107927) Bacillus subtilis subsp. subtilis str. 168 937690 NP_391880.2 CDS yxnA NC_000964.3 4108058 4109128 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 4108058..4109128 Bacillus subtilis subsp. subtilis str. 168 937698 NP_391881.1 CDS yxaD NC_000964.3 4109185 4109616 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YxaD complement(4109185..4109616) Bacillus subtilis subsp. subtilis str. 168 937699 YP_003097798.1 CDS yxzK NC_000964.3 4109843 4110247 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; integral membrane protein YxzK 4109843..4110247 Bacillus subtilis subsp. subtilis str. 168 8303163 NP_391882.3 CDS yxaC NC_000964.3 4110217 4110909 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4110217..4110909 Bacillus subtilis subsp. subtilis str. 168 937696 NP_391883.3 CDS yxaB NC_000964.3 4110949 4111980 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18326573, 9298659; Product type pe: enzyme; general stress protein 30 complement(4110949..4111980) Bacillus subtilis subsp. subtilis str. 168 937700 NP_391884.2 CDS glxK NC_000964.3 4112073 4113221 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15771780; Product type e: enzyme; glycerate kinase complement(4112073..4113221) Bacillus subtilis subsp. subtilis str. 168 937708 NP_391885.1 CDS gntR NC_000964.3 4113417 4114148 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7476858, 7642511, 8655507; Product type r: regulator; gluconate operon transcriptional repressor 4113417..4114148 Bacillus subtilis subsp. subtilis str. 168 937710 NP_391886.1 CDS gntK NC_000964.3 4114141 4115682 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11468405, 1659648, 3020045; Product type e: enzyme; gluconokinase 4114141..4115682 Bacillus subtilis subsp. subtilis str. 168 937713 NP_391887.1 CDS gntP NC_000964.3 4115711 4117057 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 1659648, 16850406, 3020045; Product type t: transporter; gluconate permease 4115711..4117057 Bacillus subtilis subsp. subtilis str. 168 937715 NP_391888.1 CDS gntZ NC_000964.3 4117080 4118486 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 4117080..4118486 Bacillus subtilis subsp. subtilis str. 168 937716 NP_391889.1 CDS ahpC NC_000964.3 4118950 4119513 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 8932315; Product type e: enzyme; alkyl hydroperoxide reductase subunit C 4118950..4119513 Bacillus subtilis subsp. subtilis str. 168 938147 NP_391890.1 CDS ahpF NC_000964.3 4119527 4121056 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 16232966, 8932314; Product type e: enzyme; NADH dehydrogenase 4119527..4121056 Bacillus subtilis subsp. subtilis str. 168 937717 NP_391891.1 CDS bglA NC_000964.3 4121166 4122605 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglA complement(4121166..4122605) Bacillus subtilis subsp. subtilis str. 168 937718 NP_391892.1 CDS yyzE NC_000964.3 4122619 4122849 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12867744; Product type pt : transporter; PTS system transporter subunit IIA YyzE complement(4122619..4122849) Bacillus subtilis subsp. subtilis str. 168 937724 NP_391893.1 CDS yydK NC_000964.3 4123193 4123903 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YydK 4123193..4123903 Bacillus subtilis subsp. subtilis str. 168 937726 YP_003097799.1 CDS yyzN NC_000964.3 4123931 4124089 D Evidence 5: No homology to any previously reported sequences; membrane protein 4123931..4124089 Bacillus subtilis subsp. subtilis str. 168 8302916 NP_391894.1 CDS yydJ NC_000964.3 4124220 4124942 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type t: transporter; peptide export permease protein YydJ complement(4124220..4124942) Bacillus subtilis subsp. subtilis str. 168 937730 NP_391895.1 CDS yydI NC_000964.3 4124963 4125592 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 17921301; Product type t: transporter; peptide export ATP-binding protein YydI complement(4124963..4125592) Bacillus subtilis subsp. subtilis str. 168 937743 NP_391896.2 CDS yydH NC_000964.3 4125742 4126500 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type pt: transporter; peptide zinc metalloprotease protein YydH complement(4125742..4126500) Bacillus subtilis subsp. subtilis str. 168 937745 NP_391897.1 CDS yydG NC_000964.3 4126481 4127440 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17921301, 18307109; Product type pe: enzyme; peptide biosynthesis protein YydG complement(4126481..4127440) Bacillus subtilis subsp. subtilis str. 168 937720 NP_391898.1 CDS yydF NC_000964.3 4127498 4127647 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989, 17921301; Product type f: factor; hypothetical protein complement(4127498..4127647) Bacillus subtilis subsp. subtilis str. 168 937753 NP_391899.1 CDS fbp NC_000964.3 4128029 4130044 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9696785; Product type e : enzyme; fructose-1,6-bisphosphatase 4128029..4130044 Bacillus subtilis subsp. subtilis str. 168 937744 NP_391900.1 CDS yydD NC_000964.3 4130578 4132338 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4130578..4132338) Bacillus subtilis subsp. subtilis str. 168 937732 NP_391901.1 CDS yydC NC_000964.3 4132338 4132736 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4132338..4132736) Bacillus subtilis subsp. subtilis str. 168 937731 NP_391902.1 CDS yydB NC_000964.3 4132729 4134174 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase complement(4132729..4134174) Bacillus subtilis subsp. subtilis str. 168 937728 NP_391903.1 CDS yydA NC_000964.3 4134436 4134915 R SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; ribosomal RNA large subunit methyltransferase H complement(4134436..4134915) Bacillus subtilis subsp. subtilis str. 168 937752 YP_003097800.1 CDS yyzF NC_000964.3 4134996 4135166 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4134996..4135166) Bacillus subtilis subsp. subtilis str. 168 8303139 NP_391904.1 CDS yycS NC_000964.3 4135351 4135764 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 4135351..4135764 Bacillus subtilis subsp. subtilis str. 168 938490 NP_391905.1 CDS yycR NC_000964.3 4135798 4137024 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; zinc-type alcohol dehydrogenase complement(4135798..4137024) Bacillus subtilis subsp. subtilis str. 168 937754 YP_003097801.1 CDS yyzG NC_000964.3 4137087 4137257 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(4137087..4137257) Bacillus subtilis subsp. subtilis str. 168 8303112 NP_391906.1 CDS yycQ NC_000964.3 4137362 4137610 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein complement(4137362..4137610) Bacillus subtilis subsp. subtilis str. 168 937733 NP_391907.2 CDS yycP NC_000964.3 4137626 4138789 R Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11557812, 16291680; hypothetical protein complement(4137626..4138789) Bacillus subtilis subsp. subtilis str. 168 937764 NP_391908.1 CDS yycO NC_000964.3 4138800 4139537 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4138800..4139537) Bacillus subtilis subsp. subtilis str. 168 937766 NP_391909.1 CDS yycN NC_000964.3 4139679 4140149 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14635137; Product type pe : enzyme; N-acetyltransferase YycN complement(4139679..4140149) Bacillus subtilis subsp. subtilis str. 168 937725 NP_391910.1 CDS rapG NC_000964.3 4140260 4141357 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878; Product type e: enzyme; response regulator aspartate phosphatase G 4140260..4141357 Bacillus subtilis subsp. subtilis str. 168 937771 NP_391911.1 CDS phrG NC_000964.3 4141358 4141474 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878, 16816200; Product type r: regulator; phosphatase RapG inhibitor 4141358..4141474 Bacillus subtilis subsp. subtilis str. 168 937767 NP_391912.1 CDS argI NC_000964.3 4141711 4142601 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10931887, 7540694; Product type e: enzyme; arginase complement(4141711..4142601) Bacillus subtilis subsp. subtilis str. 168 937760 NP_391913.1 CDS rocE NC_000964.3 4142675 4144078 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10648515, 15849754, 16850406, 7540694; Product type t: transporter; amino acid permease RocE complement(4142675..4144078) Bacillus subtilis subsp. subtilis str. 168 937761 NP_391914.1 CDS rocD NC_000964.3 4144301 4145506 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7540694, 9383188; Product type e: enzyme; ornithine aminotransferase complement(4144301..4145506) Bacillus subtilis subsp. subtilis str. 168 937755 NP_391915.1 CDS rocR NC_000964.3 4145747 4147132 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533460, 12634342, 9194709; Product type r: regulator; arginine utilization regulatory protein RocR 4145747..4147132 Bacillus subtilis subsp. subtilis str. 168 937769 NP_391916.1 CDS htrC NC_000964.3 4147567 4148769 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10692364, 11133960, 16030236; Product type pe: enzyme; serine protease YyxA complement(4147567..4148769) Bacillus subtilis subsp. subtilis str. 168 937779 NP_391917.2 CDS yycJ NC_000964.3 4148851 4149645 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16030236; Product type pe : enzyme; metallo-hydrolase YycJ complement(4148851..4149645) Bacillus subtilis subsp. subtilis str. 168 937778 NP_391918.1 CDS yycI NC_000964.3 4149667 4150509 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 17307848, 17307850; Product type r: regulator; two-component system YycFG regulatory protein complement(4149667..4150509) Bacillus subtilis subsp. subtilis str. 168 937765 NP_391919.1 CDS walH NC_000964.3 4150496 4151863 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 16600972, 17307850; Product type r: regulator; two-component system YycF/YycG regulatory protein YycH complement(4150496..4151863) Bacillus subtilis subsp. subtilis str. 168 937790 NP_391920.1 CDS walK NC_000964.3 4151853 4153688 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 19019149; Product type rc: receptor; sensor histidine kinase complement(4151853..4153688) Bacillus subtilis subsp. subtilis str. 168 937793 NP_391921.1 CDS walR NC_000964.3 4153696 4154403 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 18789936, 19019149; Product type r: regulator; transcriptional regulator complement(4153696..4154403) Bacillus subtilis subsp. subtilis str. 168 937776 NP_391922.1 CDS purA NC_000964.3 4155433 4156725 R catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase complement(4155433..4156725) Bacillus subtilis subsp. subtilis str. 168 937805 NP_391923.1 CDS yycE NC_000964.3 4156931 4157350 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4156931..4157350) Bacillus subtilis subsp. subtilis str. 168 937806 NP_391924.2 CDS dnaC NC_000964.3 4157471 4158835 R unwinds double stranded DNA; replicative DNA helicase complement(4157471..4158835) Bacillus subtilis subsp. subtilis str. 168 937810 NP_391925.1 CDS yycD NC_000964.3 4159005 4159205 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4159005..4159205 Bacillus subtilis subsp. subtilis str. 168 937781 NP_391926.1 CDS yyzB NC_000964.3 4159253 4159456 R Evidence 5: No homology to any previously reported sequences; hypothetical protein complement(4159253..4159456) Bacillus subtilis subsp. subtilis str. 168 937821 NP_391927.1 CDS yycC NC_000964.3 4159577 4159717 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4159577..4159717 Bacillus subtilis subsp. subtilis str. 168 937823 NP_391928.1 CDS yycB NC_000964.3 4159790 4160998 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4159790..4160998 Bacillus subtilis subsp. subtilis str. 168 937777 NP_391929.2 CDS yycA NC_000964.3 4161103 4163160 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; mannosyltransferase YycA 4161103..4163160 Bacillus subtilis subsp. subtilis str. 168 937828 NP_391930.1 CDS rplI NC_000964.3 4163197 4163646 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(4163197..4163646) Bacillus subtilis subsp. subtilis str. 168 937830 NP_391931.1 CDS yybT NC_000964.3 4163643 4165622 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4163643..4165622) Bacillus subtilis subsp. subtilis str. 168 937816 NP_391932.1 CDS yybS NC_000964.3 4165659 4166588 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4165659..4166588) Bacillus subtilis subsp. subtilis str. 168 937844 YP_003097802.1 CDS yyzH NC_000964.3 4166815 4166964 R Evidence 5: No homology to any previously reported sequences; membrane protein complement(4166815..4166964) Bacillus subtilis subsp. subtilis str. 168 8302993 NP_391933.1 CDS cotF NC_000964.3 4167110 4167592 D Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1708381; Product type f : factor; spore coat protein F 4167110..4167592 Bacillus subtilis subsp. subtilis str. 168 936671 NP_391934.1 CDS yybR NC_000964.3 4167622 4167999 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybR complement(4167622..4167999) Bacillus subtilis subsp. subtilis str. 168 937825 NP_391935.1 CDS ppaC NC_000964.3 4168204 4169133 D catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 4168204..4169133 Bacillus subtilis subsp. subtilis str. 168 937817 NP_391936.1 CDS yybP NC_000964.3 4169166 4169612 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624; Product type pt : transporter; lipoprotein complement(4169166..4169612) Bacillus subtilis subsp. subtilis str. 168 937851 NP_391937.1 CDS yybO NC_000964.3 4170045 4171352 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4170045..4171352 Bacillus subtilis subsp. subtilis str. 168 937836 NP_391938.1 CDS yybN NC_000964.3 4173114 4173551 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4173114..4173551 Bacillus subtilis subsp. subtilis str. 168 937850 NP_391939.1 CDS yybM NC_000964.3 4173665 4174420 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4173665..4174420 Bacillus subtilis subsp. subtilis str. 168 937824 NP_391940.1 CDS yybL NC_000964.3 4174410 4175120 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4174410..4175120 Bacillus subtilis subsp. subtilis str. 168 936529 NP_391941.1 CDS yybK NC_000964.3 4175117 4175872 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4175117..4175872 Bacillus subtilis subsp. subtilis str. 168 938116 NP_391942.1 CDS yybJ NC_000964.3 4175869 4176525 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1938973; Product type pe : enzyme; ABC transporter ATP-binding protein 4175869..4176525 Bacillus subtilis subsp. subtilis str. 168 937807 NP_391943.1 CDS yybI NC_000964.3 4176900 4177688 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process; hypothetical protein complement(4176900..4177688) Bacillus subtilis subsp. subtilis str. 168 937811 NP_391944.1 CDS yybH NC_000964.3 4177756 4178145 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4177756..4178145) Bacillus subtilis subsp. subtilis str. 168 937866 NP_391945.1 CDS yybG NC_000964.3 4178291 4179130 D Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11709313; hypothetical protein 4178291..4179130 Bacillus subtilis subsp. subtilis str. 168 937852 NP_391946.1 CDS yybF NC_000964.3 4179163 4180377 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9811656; Product type pt: transporter; MFS transporter complement(4179163..4180377) Bacillus subtilis subsp. subtilis str. 168 937854 NP_391947.2 CDS yybE NC_000964.3 4180564 4181442 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybE 4180564..4181442 Bacillus subtilis subsp. subtilis str. 168 937875 NP_391948.1 CDS yybD NC_000964.3 4181456 4181899 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4181456..4181899 Bacillus subtilis subsp. subtilis str. 168 938072 NP_391949.1 CDS yybC NC_000964.3 4181982 4182461 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4181982..4182461 Bacillus subtilis subsp. subtilis str. 168 937862 NP_391950.1 CDS yybB NC_000964.3 4182636 4183298 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4182636..4183298) Bacillus subtilis subsp. subtilis str. 168 937880 NP_391951.1 CDS yybA NC_000964.3 4183445 4183897 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybA complement(4183445..4183897) Bacillus subtilis subsp. subtilis str. 168 937872 NP_391952.1 CDS yyaT NC_000964.3 4184017 4184463 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4184017..4184463 Bacillus subtilis subsp. subtilis str. 168 937874 NP_391953.1 CDS yyaS NC_000964.3 4184460 4185065 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4184460..4185065 Bacillus subtilis subsp. subtilis str. 168 937921 NP_391954.1 CDS yyaR NC_000964.3 4185160 4185681 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16579456; Product type pe : enzyme; hypothetical protein complement(4185160..4185681) Bacillus subtilis subsp. subtilis str. 168 937878 NP_391955.1 CDS yyaQ NC_000964.3 4186092 4186448 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4186092..4186448 Bacillus subtilis subsp. subtilis str. 168 937883 NP_391956.1 CDS yyaP NC_000964.3 4186608 4187174 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4186608..4187174 Bacillus subtilis subsp. subtilis str. 168 937903 NP_391957.1 CDS tetB NC_000964.3 4187681 4189057 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636065, 15849754, 16850406, 17015648, 7961647; Product type t : transporter; tetracycline resistance protein complement(4187681..4189057) Bacillus subtilis subsp. subtilis str. 168 937890 NP_391959.1 CDS yyaO NC_000964.3 4189406 4189645 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4189406..4189645 Bacillus subtilis subsp. subtilis str. 168 937882 NP_391960.1 CDS yyaN NC_000964.3 4189796 4190212 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator; HTH-type transcriptional regulator YyaN 4189796..4190212 Bacillus subtilis subsp. subtilis str. 168 937892 NP_391961.1 CDS yyaM NC_000964.3 4190209 4191126 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4190209..4191126 Bacillus subtilis subsp. subtilis str. 168 937895 NP_391962.1 CDS yyaL NC_000964.3 4191198 4193267 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4191198..4193267 Bacillus subtilis subsp. subtilis str. 168 937904 NP_391963.1 CDS yyaK NC_000964.3 4193264 4194163 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein complement(4193264..4194163) Bacillus subtilis subsp. subtilis str. 168 937893 NP_391964.2 CDS yyaJ NC_000964.3 4194389 4195744 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9529885; Product type pt: transporter; metabolite transport protein YyaJ 4194389..4195744 Bacillus subtilis subsp. subtilis str. 168 937884 NP_391965.1 CDS maa NC_000964.3 4195778 4196332 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12731863, 12793527; Product type e: enzyme; maltose O-acetyltransferase complement(4195778..4196332) Bacillus subtilis subsp. subtilis str. 168 937913 NP_391966.1 CDS yyaH NC_000964.3 4196350 4196730 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein complement(4196350..4196730) Bacillus subtilis subsp. subtilis str. 168 937879 NP_391967.1 CDS ccpB NC_000964.3 4196786 4197721 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267306, 9457849, 9642180; Product type r: regulator; catabolite control protein B complement(4196786..4197721) Bacillus subtilis subsp. subtilis str. 168 937876 NP_391968.1 CDS exoAA NC_000964.3 4197780 4198538 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10540738, 16237020, 18203828; Product type e: enzyme; exodeoxyribonuclease complement(4197780..4198538) Bacillus subtilis subsp. subtilis str. 168 937918 NP_391969.2 CDS rpsR NC_000964.3 4198603 4198842 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(4198603..4198842) Bacillus subtilis subsp. subtilis str. 168 937906 NP_391970.1 CDS ssbA NC_000964.3 4198886 4199404 R Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14762004, 16549871, 10072765; Product type f: factor; single-stranded DNA-binding protein complement(4198886..4199404) Bacillus subtilis subsp. subtilis str. 168 937911 NP_391971.1 CDS rpsF NC_000964.3 4199445 4199732 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(4199445..4199732) Bacillus subtilis subsp. subtilis str. 168 937919 NP_391972.1 CDS yyaF NC_000964.3 4199843 4200943 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(4199843..4200943) Bacillus subtilis subsp. subtilis str. 168 937916 NP_391973.1 CDS yyaE NC_000964.3 4201070 4203073 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114254; Product type pe : enzyme; oxidoreductase complement(4201070..4203073) Bacillus subtilis subsp. subtilis str. 168 937914 YP_003097803.1 CDS yyzM NC_000964.3 4203124 4203330 R Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein complement(4203124..4203330) Bacillus subtilis subsp. subtilis str. 168 8302952 NP_391974.1 CDS yyaD NC_000964.3 4203424 4204440 R Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16847258, 16850406; Product type pt: transporter; hypothetical protein complement(4203424..4204440) Bacillus subtilis subsp. subtilis str. 168 937923 NP_391975.1 CDS yyaC NC_000964.3 4204900 4205517 D Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4204900..4205517 Bacillus subtilis subsp. subtilis str. 168 937925 NP_391976.1 CDS parB NC_000964.3 4205556 4206404 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298; Product type f : factor; stage 0 sporulation protein J complement(4205556..4206404) Bacillus subtilis subsp. subtilis str. 168 937907 NP_391977.1 CDS parA NC_000964.3 4206397 4207158 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 18077387; Product type f: factor; sporulation initiation inhibitor protein Soj complement(4206397..4207158) Bacillus subtilis subsp. subtilis str. 168 937928 NP_391978.2 CDS yyaB NC_000964.3 4207406 4207846 D Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4207406..4207846 Bacillus subtilis subsp. subtilis str. 168 937929 NP_391979.1 CDS noc NC_000964.3 4207897 4208748 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807071, 15210112, 16549676; Product type f: factor; nucleoid occlusion protein complement(4207897..4208748) Bacillus subtilis subsp. subtilis str. 168 937920 NP_391980.1 CDS gidB NC_000964.3 4208870 4209589 R glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; ribosomal RNA small subunit methyltransferase G complement(4208870..4209589) Bacillus subtilis subsp. subtilis str. 168 937931 NP_391981.1 CDS gidA NC_000964.3 4209603 4211489 R GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG complement(4209603..4211489) Bacillus subtilis subsp. subtilis str. 168 937932 NP_391982.1 CDS trmE NC_000964.3 4211510 4212889 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase MnmE complement(4211510..4212889) Bacillus subtilis subsp. subtilis str. 168 937927 NP_391983.1 CDS jag NC_000964.3 4213200 4213826 R Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12813085, 1487728; Product type f: factor; protein jag complement(4213200..4213826) Bacillus subtilis subsp. subtilis str. 168 937933 NP_391984.1 CDS spoIIIJ NC_000964.3 4213823 4214608 R involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation; membrane protein insertase MisCA complement(4213823..4214608) Bacillus subtilis subsp. subtilis str. 168 937934 NP_391985.1 CDS rnpA NC_000964.3 4214753 4215103 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P protein component complement(4214753..4215103) Bacillus subtilis subsp. subtilis str. 168 937930 NP_391986.1 CDS rpmH NC_000964.3 4215255 4215389 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(4215255..4215389) Bacillus subtilis subsp. subtilis str. 168 937942 BSU_tRNA_5 tRNA trnO-Ile NC_000964.3 11464 11540 D tRNA-Ile 11464..11540 Bacillus subtilis subsp. subtilis str. 168 2914186 BSU_tRNA_6 tRNA trnO-Ala NC_000964.3 11552 11627 D tRNA-Ala 11552..11627 Bacillus subtilis subsp. subtilis str. 168 939967 BSU_tRNA_7 tRNA trnSL-Ser1 NC_000964.3 22292 22384 D tRNA-Ser 22292..22384 Bacillus subtilis subsp. subtilis str. 168 2914247 BSU_tRNA_8 tRNA trnA-Ile NC_000964.3 31932 32008 D tRNA-Ile 31932..32008 Bacillus subtilis subsp. subtilis str. 168 2914254 BSU_tRNA_9 tRNA trnA-Ala NC_000964.3 32020 32095 D tRNA-Ala 32020..32095 Bacillus subtilis subsp. subtilis str. 168 2914217 BSU_tRNA_10 tRNA trnSL-Met1 NC_000964.3 70181 70257 D tRNA-Met 70181..70257 Bacillus subtilis subsp. subtilis str. 168 936631 BSU_tRNA_11 tRNA trnSL-Glu1 NC_000964.3 70267 70338 D tRNA-Glu 70267..70338 Bacillus subtilis subsp. subtilis str. 168 2914278 BSU_tRNA_12 tRNA trnJ-Val NC_000964.3 95375 95450 D tRNA-Val 95375..95450 Bacillus subtilis subsp. subtilis str. 168 936902 BSU_tRNA_13 tRNA trnJ-Thr NC_000964.3 95455 95530 D tRNA-Thr 95455..95530 Bacillus subtilis subsp. subtilis str. 168 936811 BSU_tRNA_14 tRNA trnJ-Lys NC_000964.3 95567 95642 D tRNA-Lys 95567..95642 Bacillus subtilis subsp. subtilis str. 168 936901 BSU_tRNA_15 tRNA trnJ-Leu1 NC_000964.3 95649 95731 D tRNA-Leu 95649..95731 Bacillus subtilis subsp. subtilis str. 168 2914251 BSU_tRNA_16 tRNA trnJ-Gly NC_000964.3 95772 95846 D tRNA-Gly 95772..95846 Bacillus subtilis subsp. subtilis str. 168 936900 BSU_tRNA_17 tRNA trnJ-Leu2 NC_000964.3 95861 95946 D tRNA-Leu 95861..95946 Bacillus subtilis subsp. subtilis str. 168 2914249 BSU_tRNA_18 tRNA trnJ-Arg NC_000964.3 95956 96032 D tRNA-Arg 95956..96032 Bacillus subtilis subsp. subtilis str. 168 936780 BSU_tRNA_19 tRNA trnJ-Pro NC_000964.3 96060 96136 D tRNA-Pro 96060..96136 Bacillus subtilis subsp. subtilis str. 168 936611 BSU_tRNA_20 tRNA trnJ-Ala NC_000964.3 96146 96221 D tRNA-Ala 96146..96221 Bacillus subtilis subsp. subtilis str. 168 2914268 BSU_tRNA_23 tRNA trnI-Asn NC_000964.3 165754 165825 D tRNA-Asn 165754..165825 Bacillus subtilis subsp. subtilis str. 168 2914257 BSU_tRNA_24 tRNA trnI-Thr NC_000964.3 165830 165902 D tRNA-Thr 165830..165902 Bacillus subtilis subsp. subtilis str. 168 2914258 BSU_tRNA_25 tRNA trnI-Gly NC_000964.3 165959 166033 D tRNA-Gly 165959..166033 Bacillus subtilis subsp. subtilis str. 168 938904 BSU_tRNA_26 tRNA trnI-Arg NC_000964.3 166064 166140 D tRNA-Arg 166064..166140 Bacillus subtilis subsp. subtilis str. 168 938903 BSU_tRNA_27 tRNA trnI-Pro NC_000964.3 166168 166244 D tRNA-Pro 166168..166244 Bacillus subtilis subsp. subtilis str. 168 938902 BSU_tRNA_28 tRNA trnI-Ala NC_000964.3 166253 166328 D tRNA-Ala 166253..166328 Bacillus subtilis subsp. subtilis str. 168 2914261 BSU_tRNA_75 tRNA trnSL-Glu2 NC_000964.3 194205 194279 D tRNA-Glu 194205..194279 Bacillus subtilis subsp. subtilis str. 168 8303028 BSU_tRNA_78 tRNA trnSL-Val1 NC_000964.3 194283 194358 D tRNA-Val 194283..194358 Bacillus subtilis subsp. subtilis str. 168 8302937 BSU_tRNA_76 tRNA trnSL-Thr1 NC_000964.3 194363 194435 D tRNA-Thr 194363..194435 Bacillus subtilis subsp. subtilis str. 168 8303065 BSU_tRNA_77 tRNA trnSL-Tyr1 NC_000964.3 194458 194542 D tRNA-Tyr 194458..194542 Bacillus subtilis subsp. subtilis str. 168 8303046 BSU_tRNA_74 tRNA trnSL-Gln2 NC_000964.3 194547 194621 D tRNA-Gln 194547..194621 Bacillus subtilis subsp. subtilis str. 168 8303064 BSU_tRNA_45 tRNA trnS-Asn NC_000964.3 528704 528778 D tRNA-Asn 528704..528778 Bacillus subtilis subsp. subtilis str. 168 8302928 BSU_tRNA_46 tRNA trnS-Ser NC_000964.3 528783 528873 D tRNA-Ser 528783..528873 Bacillus subtilis subsp. subtilis str. 168 8302954 BSU_tRNA_47 tRNA trnS-Glu NC_000964.3 528903 528974 D tRNA-Glu 528903..528974 Bacillus subtilis subsp. subtilis str. 168 8303006 BSU_tRNA_48 tRNA trnS-Gln NC_000964.3 528986 529060 D tRNA-Gln 528986..529060 Bacillus subtilis subsp. subtilis str. 168 8302925 BSU_tRNA_49 tRNA trnS-Lys NC_000964.3 529087 529162 D tRNA-Lys 529087..529162 Bacillus subtilis subsp. subtilis str. 168 8302955 BSU_tRNA_50 tRNA trnS-Leu1 NC_000964.3 529174 529255 D tRNA-Leu 529174..529255 Bacillus subtilis subsp. subtilis str. 168 8302923 BSU_tRNA_51 tRNA trnS-Leu2 NC_000964.3 529336 529422 D tRNA-Leu 529336..529422 Bacillus subtilis subsp. subtilis str. 168 8302926 BSU_tRNA_79 tRNA trnE-Arg NC_000964.3 635110 635186 D tRNA-Arg 635110..635186 Bacillus subtilis subsp. subtilis str. 168 8303218 BSU_tRNA_80 tRNA trnE-Gly NC_000964.3 635200 635273 D tRNA-Gly 635200..635273 Bacillus subtilis subsp. subtilis str. 168 8303060 BSU_tRNA_21 tRNA trnE-Met NC_000964.3 640268 640344 D tRNA-Met 640268..640344 Bacillus subtilis subsp. subtilis str. 168 8303207 BSU_tRNA_22 tRNA trnE-Asp NC_000964.3 640405 640481 D tRNA-Asp 640405..640481 Bacillus subtilis subsp. subtilis str. 168 8303086 BSU_tRNA_29 tRNA trnD-Asn NC_000964.3 951582 951656 D tRNA-Asn 951582..951656 Bacillus subtilis subsp. subtilis str. 168 8303214 BSU_tRNA_30 tRNA trnD-Ser NC_000964.3 951662 951753 D tRNA-Ser 951662..951753 Bacillus subtilis subsp. subtilis str. 168 8303016 BSU_tRNA_31 tRNA trnD-Glu NC_000964.3 951788 951859 D tRNA-Glu 951788..951859 Bacillus subtilis subsp. subtilis str. 168 8303051 BSU_tRNA_32 tRNA trnD-Val NC_000964.3 951869 951944 D tRNA-Val 951869..951944 Bacillus subtilis subsp. subtilis str. 168 8303018 BSU_tRNA_33 tRNA trnD-Met NC_000964.3 951954 952030 D tRNA-Met 951954..952030 Bacillus subtilis subsp. subtilis str. 168 8302934 BSU_tRNA_34 tRNA trnD-Asp NC_000964.3 952042 952118 D tRNA-Asp 952042..952118 Bacillus subtilis subsp. subtilis str. 168 8303039 BSU_tRNA_35 tRNA trnD-Phe NC_000964.3 952131 952206 D tRNA-Phe 952131..952206 Bacillus subtilis subsp. subtilis str. 168 8303017 BSU_tRNA_36 tRNA trnD-Thr NC_000964.3 952212 952284 D tRNA-Thr 952212..952284 Bacillus subtilis subsp. subtilis str. 168 8303050 BSU_tRNA_37 tRNA trnD-Tyr NC_000964.3 952307 952391 D tRNA-Tyr 952307..952391 Bacillus subtilis subsp. subtilis str. 168 8303087 BSU_tRNA_38 tRNA trnD-Trp NC_000964.3 952397 952470 D tRNA-Trp 952397..952470 Bacillus subtilis subsp. subtilis str. 168 8302933 BSU_tRNA_39 tRNA trnD-His NC_000964.3 952495 952570 D tRNA-His 952495..952570 Bacillus subtilis subsp. subtilis str. 168 8303088 BSU_tRNA_40 tRNA trnD-Gln NC_000964.3 952580 952651 D tRNA-Gln 952580..952651 Bacillus subtilis subsp. subtilis str. 168 8303076 BSU_tRNA_41 tRNA trnD-Gly NC_000964.3 952701 952775 D tRNA-Gly 952701..952775 Bacillus subtilis subsp. subtilis str. 168 8303097 BSU_tRNA_42 tRNA trnD-Cys NC_000964.3 952781 952851 D tRNA-Cys 952781..952851 Bacillus subtilis subsp. subtilis str. 168 8303019 BSU_tRNA_43 tRNA trnD-Leu1 NC_000964.3 952859 952947 D tRNA-Leu 952859..952947 Bacillus subtilis subsp. subtilis str. 168 8303096 BSU_tRNA_44 tRNA trnD-Leu2 NC_000964.3 953213 953294 D tRNA-Leu 953213..953294 Bacillus subtilis subsp. subtilis str. 168 8303077 BSU_tRNA_82 tRNA trnSL-Gly1 NC_000964.3 967065 967138 D tRNA-Gly 967065..967138 Bacillus subtilis subsp. subtilis str. 168 8302935 BSU_tRNA_83 tRNA trnSL-Val2 NC_000964.3 1262789 1262861 D tRNA-Val 1262789..1262861 Bacillus subtilis subsp. subtilis str. 168 8303193 BSU_tRNA_85 tRNA trnSL-Arg1 NC_000964.3 2003276 2003348 R tRNA-Arg complement(2003276..2003348) Bacillus subtilis subsp. subtilis str. 168 8303040 BSU_tRNA_73 tRNA trnSL-Gln1 NC_000964.3 2563889 2563959 D tRNA-Gln 2563889..2563959 Bacillus subtilis subsp. subtilis str. 168 8303182 BSU_tRNA_84 tRNA trnSL-Arg2 NC_000964.3 2899816 2899889 R tRNA-Arg complement(2899816..2899889) Bacillus subtilis subsp. subtilis str. 168 8303222 BSU_tRNA_72 tRNA trnB-Glu NC_000964.3 3171879 3171950 R tRNA-Glu complement(3171879..3171950) Bacillus subtilis subsp. subtilis str. 168 8302911 BSU_tRNA_71 tRNA trnB-Ser2 NC_000964.3 3171976 3172066 R tRNA-Ser complement(3171976..3172066) Bacillus subtilis subsp. subtilis str. 168 8303036 BSU_tRNA_70 tRNA trnB-Asn NC_000964.3 3172070 3172144 R tRNA-Asn complement(3172070..3172144) Bacillus subtilis subsp. subtilis str. 168 8303101 BSU_tRNA_69 tRNA trnB-Ile2 NC_000964.3 3172155 3172231 R tRNA-Ile complement(3172155..3172231) Bacillus subtilis subsp. subtilis str. 168 8303002 BSU_tRNA_68 tRNA trnB-Gly2 NC_000964.3 3172247 3172320 R tRNA-Gly complement(3172247..3172320) Bacillus subtilis subsp. subtilis str. 168 8303081 BSU_tRNA_67 tRNA trnB-His NC_000964.3 3172331 3172406 R tRNA-His complement(3172331..3172406) Bacillus subtilis subsp. subtilis str. 168 8302964 BSU_tRNA_66 tRNA trnB-Phe NC_000964.3 3172424 3172499 R tRNA-Phe complement(3172424..3172499) Bacillus subtilis subsp. subtilis str. 168 8303080 BSU_tRNA_65 tRNA trnB-Asp NC_000964.3 3172512 3172588 R tRNA-Asp complement(3172512..3172588) Bacillus subtilis subsp. subtilis str. 168 8303106 BSU_tRNA_64 tRNA trnB-Met2 NC_000964.3 3172600 3172676 R tRNA-Met complement(3172600..3172676) Bacillus subtilis subsp. subtilis str. 168 8303035 BSU_tRNA_63 tRNA trnB-Ser1 NC_000964.3 3172694 3172786 R tRNA-Ser complement(3172694..3172786) Bacillus subtilis subsp. subtilis str. 168 8302960 BSU_tRNA_62 tRNA trnB-Met3 NC_000964.3 3172793 3172869 R tRNA-Met complement(3172793..3172869) Bacillus subtilis subsp. subtilis str. 168 8303100 BSU_tRNA_61 tRNA trnB-Met1 NC_000964.3 3172872 3172948 R tRNA-Met complement(3172872..3172948) Bacillus subtilis subsp. subtilis str. 168 8302961 BSU_tRNA_60 tRNA trnB-Ala NC_000964.3 3172968 3173040 R tRNA-Ala complement(3172968..3173040) Bacillus subtilis subsp. subtilis str. 168 8303103 BSU_tRNA_59 tRNA trnB-Pro NC_000964.3 3173046 3173122 R tRNA-Pro complement(3173046..3173122) Bacillus subtilis subsp. subtilis str. 168 8303114 BSU_tRNA_58 tRNA trnB-Arg NC_000964.3 3173138 3173214 R tRNA-Arg complement(3173138..3173214) Bacillus subtilis subsp. subtilis str. 168 8303107 BSU_tRNA_57 tRNA trnB-Leu2 NC_000964.3 3173224 3173309 R tRNA-Leu complement(3173224..3173309) Bacillus subtilis subsp. subtilis str. 168 8303001 BSU_tRNA_56 tRNA trnB-Gly1 NC_000964.3 3173324 3173398 R tRNA-Gly complement(3173324..3173398) Bacillus subtilis subsp. subtilis str. 168 8302986 BSU_tRNA_55 tRNA trnB-Leu1 NC_000964.3 3173404 3173490 R tRNA-Leu complement(3173404..3173490) Bacillus subtilis subsp. subtilis str. 168 8302963 BSU_tRNA_54 tRNA trnB-Lys NC_000964.3 3173501 3173576 R tRNA-Lys complement(3173501..3173576) Bacillus subtilis subsp. subtilis str. 168 8302985 BSU_tRNA_53 tRNA trnB-Thr NC_000964.3 3173614 3173689 R tRNA-Thr complement(3173614..3173689) Bacillus subtilis subsp. subtilis str. 168 8303102 BSU_tRNA_52 tRNA trnB-Val NC_000964.3 3173722 3173797 R tRNA-Val complement(3173722..3173797) Bacillus subtilis subsp. subtilis str. 168 8303024 BSU_tRNA_86 tRNA trnSL-Ala1 NC_000964.3 3194455 3194527 R tRNA-Ala complement(3194455..3194527) Bacillus subtilis subsp. subtilis str. 168 8303184 BSU_tRNA_81 tRNA trnQ-Arg NC_000964.3 3545889 3545964 R tRNA-Arg complement(3545889..3545964) Bacillus subtilis subsp. subtilis str. 168 8303047 BSU_tRNA_1 tRNA trnY-Phe NC_000964.3 4154787 4154859 R tRNA-Phe complement(4154787..4154859) Bacillus subtilis subsp. subtilis str. 168 8303145 BSU_tRNA_2 tRNA trnY-Asp NC_000964.3 4154895 4154971 R tRNA-Asp complement(4154895..4154971) Bacillus subtilis subsp. subtilis str. 168 8302974 BSU_tRNA_3 tRNA trnY-Glu NC_000964.3 4155053 4155124 R tRNA-Glu complement(4155053..4155124) Bacillus subtilis subsp. subtilis str. 168 8303042 BSU_tRNA_4 tRNA trnY-Lys NC_000964.3 4155134 4155209 R tRNA-Lys complement(4155134..4155209) Bacillus subtilis subsp. subtilis str. 168 8302915 BSU_rRNA_1 rRNA rrnO-16S NC_000964.3 9810 11364 D ribosomal RNA-16S 9810..11364 Bacillus subtilis subsp. subtilis str. 168 936774 BSU_rRNA_2 rRNA rrnO-23S NC_000964.3 11709 14636 D ribosomal RNA-23S 11709..14636 Bacillus subtilis subsp. subtilis str. 168 939981 BSU_rRNA_3 rRNA rrnO-5S NC_000964.3 14692 14810 D ribosomal RNA-5S 14692..14810 Bacillus subtilis subsp. subtilis str. 168 2914271 BSU_rRNA_4 rRNA rrnA-16S NC_000964.3 30279 31832 D ribosomal RNA-16S 30279..31832 Bacillus subtilis subsp. subtilis str. 168 936895 BSU_rRNA_5 rRNA rrnA-23S NC_000964.3 32177 35103 D ribosomal RNA-23S 32177..35103 Bacillus subtilis subsp. subtilis str. 168 936943 BSU_rRNA_26 rRNA rrnA-5S NC_000964.3 35237 35355 D ribosomal RNA-5S 35237..35355 Bacillus subtilis subsp. subtilis str. 168 2914205 BSU_rRNA_6 rRNA rrnJ-16S NC_000964.3 90536 92089 D ribosomal RNA-16S 90536..92089 Bacillus subtilis subsp. subtilis str. 168 936409 BSU_rRNA_7 rRNA rrnJ-23S NC_000964.3 92254 95181 D ribosomal RNA-23S 92254..95181 Bacillus subtilis subsp. subtilis str. 168 936612 BSU_rRNA_8 rRNA rrnJ-5S NC_000964.3 95237 95354 D ribosomal RNA-5S 95237..95354 Bacillus subtilis subsp. subtilis str. 168 936652 BSU_rRNA_9 rRNA rrnW-16S NC_000964.3 96392 97945 D ribosomal RNA-16S 96392..97945 Bacillus subtilis subsp. subtilis str. 168 936880 BSU_rRNA_10 rRNA rrnW-23S NC_000964.3 98110 101037 D ribosomal RNA-23S 98110..101037 Bacillus subtilis subsp. subtilis str. 168 936651 BSU_rRNA_11 rRNA rrnW-5S NC_000964.3 101093 101211 D ribosomal RNA-5S 101093..101211 Bacillus subtilis subsp. subtilis str. 168 2914266 BSU_rRNA_23 rRNA rrnI-16S NC_000964.3 160893 162445 D ribosomal RNA-16S 160893..162445 Bacillus subtilis subsp. subtilis str. 168 938908 BSU_rRNA_14 rRNA rrnI-23S NC_000964.3 162610 165535 D ribosomal RNA-23S 162610..165535 Bacillus subtilis subsp. subtilis str. 168 938905 BSU_rRNA_15 rRNA rrnI-5S NC_000964.3 165591 165707 D ribosomal RNA-5S 165591..165707 Bacillus subtilis subsp. subtilis str. 168 938909 BSU_rRNA_16 rRNA rrnH-16S NC_000964.3 166500 168053 D ribosomal RNA-16S 166500..168053 Bacillus subtilis subsp. subtilis str. 168 938899 BSU_rRNA_29 rRNA rrnH-23S NC_000964.3 168218 171141 D ribosomal RNA-23S 168218..171141 Bacillus subtilis subsp. subtilis str. 168 938896 BSU_rRNA_24 rRNA rrnH-5S NC_000964.3 171197 171314 D ribosomal RNA-5S 171197..171314 Bacillus subtilis subsp. subtilis str. 168 938894 BSU_rRNA_25 rRNA rrnG-16S NC_000964.3 171498 173049 D ribosomal RNA-16S 171498..173049 Bacillus subtilis subsp. subtilis str. 168 938898 BSU_rRNA_27 rRNA rrnG-23S NC_000964.3 173214 176141 D ribosomal RNA-23S 173214..176141 Bacillus subtilis subsp. subtilis str. 168 938897 BSU_rRNA_28 rRNA rrnG-5S NC_000964.3 176197 176315 D ribosomal RNA-5S 176197..176315 Bacillus subtilis subsp. subtilis str. 168 2914262 BSU_rRNA_30 rRNA rrnE-16S NC_000964.3 635433 636987 D ribosomal RNA-16S 635433..636987 Bacillus subtilis subsp. subtilis str. 168 8303085 BSU_rRNA_12 rRNA rrnE-23S NC_000964.3 637155 640082 D ribosomal RNA-23S 637155..640082 Bacillus subtilis subsp. subtilis str. 168 8303215 BSU_rRNA_13 rRNA rrnE-5S NC_000964.3 640138 640254 D ribosomal RNA-5S 640138..640254 Bacillus subtilis subsp. subtilis str. 168 8303206 BSU_rRNA_22 rRNA rrnD-16S NC_000964.3 946696 948250 D ribosomal RNA-16S 946696..948250 Bacillus subtilis subsp. subtilis str. 168 8303099 BSU_rRNA_17 rRNA rrnD-23S NC_000964.3 948418 951345 D ribosomal RNA-23S 948418..951345 Bacillus subtilis subsp. subtilis str. 168 8303208 BSU_rRNA_18 rRNA rrnD-5S NC_000964.3 951457 951572 D ribosomal RNA-5S 951457..951572 Bacillus subtilis subsp. subtilis str. 168 8303209 BSU_rRNA_21 rRNA rrnB-5S NC_000964.3 3173818 3173935 R ribosomal RNA-5S complement(3173818..3173935) Bacillus subtilis subsp. subtilis str. 168 8303025 BSU_rRNA_20 rRNA rrnB-23S NC_000964.3 3173991 3176918 R ribosomal RNA-23S complement(3173991..3176918) Bacillus subtilis subsp. subtilis str. 168 8303213 BSU_rRNA_19 rRNA rrnB-16S NC_000964.3 3177086 3178640 R ribosomal RNA-16S complement(3177086..3178640) Bacillus subtilis subsp. subtilis str. 168 8303212