-- dump date 20140618_223457 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type NP_387882.1 16077069 939978 410..1750 1 NC_000964.3 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiator protein DnaA 1750 dnaA 939978 dnaA Bacillus subtilis subsp. subtilis str. 168 chromosomal replication initiator protein DnaA NP_387882.1 410 D 224308 CDS NP_387883.1 16077070 939970 1939..3075 1 NC_000964.3 binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 3075 dnaN 939970 dnaN Bacillus subtilis subsp. subtilis str. 168 DNA polymerase III subunit beta NP_387883.1 1939 D 224308 CDS NP_387884.1 16077071 939444 3206..3421 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3421 yaaA 939444 yaaA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387884.1 3206 D 224308 CDS NP_387885.1 16077072 939454 3437..4549 1 NC_000964.3 Required for DNA replication; binds preferentially to single-stranded, linear DNA; DNA replication and repair protein RecF 4549 recF 939454 recF Bacillus subtilis subsp. subtilis str. 168 DNA replication and repair protein RecF NP_387885.1 3437 D 224308 CDS NP_387886.2 255767014 939466 4567..4812 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4812 yaaB 939466 yaaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387886.2 4567 D 224308 CDS NP_387887.1 16077074 939456 4867..6783 1 NC_000964.3 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 6783 gyrB 939456 gyrB Bacillus subtilis subsp. subtilis str. 168 DNA gyrase subunit B NP_387887.1 4867 D 224308 CDS NP_387888.1 16077075 940002 6994..9459 1 NC_000964.3 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 9459 gyrA 940002 gyrA Bacillus subtilis subsp. subtilis str. 168 DNA gyrase subunit A NP_387888.1 6994 D 224308 CDS NP_387889.1 16077076 939969 complement(14847..15794) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 15794 yaaC 939969 yaaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387889.1 14847 R 224308 CDS NP_387890.1 16077077 938032 15915..17381 1 NC_000964.3 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine-5'-monophosphate dehydrogenase 17381 guaB 938032 guaB Bacillus subtilis subsp. subtilis str. 168 inosine-5'-monophosphate dehydrogenase NP_387890.1 15915 D 224308 CDS NP_387891.1 16077078 940000 17534..18865 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8370539, 9864321; Product type e: enzyme; D-alanyl-D-alanine carboxypeptidase DacA 18865 dacA 940000 dacA Bacillus subtilis subsp. subtilis str. 168 D-alanyl-D-alanine carboxypeptidase DacA NP_387891.1 17534 D 224308 CDS NP_387892.1 16077079 939988 19062..19946 1 NC_000964.3 with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS 19946 yaaD 939988 yaaD Bacillus subtilis subsp. subtilis str. 168 pyridoxal biosynthesis lyase PdxS NP_387892.1 19062 D 224308 CDS NP_387893.1 16077080 939971 19968..20558 1 NC_000964.3 with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT 20558 yaaE 939971 yaaE Bacillus subtilis subsp. subtilis str. 168 glutamine amidotransferase subunit PdxT NP_387893.1 19968 D 224308 CDS NP_387894.1 16077081 939994 20880..22157 1 NC_000964.3 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; serine--tRNA ligase 22157 serS 939994 serS Bacillus subtilis subsp. subtilis str. 168 serine--tRNA ligase NP_387894.1 20880 D 224308 CDS NP_387895.1 16077082 936793 complement(22496..23149) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735, 6251049; Product type e: enzyme; deoxyadenosine/deoxycytidine kinase 23149 dck 936793 dck Bacillus subtilis subsp. subtilis str. 168 deoxyadenosine/deoxycytidine kinase NP_387895.1 22496 R 224308 CDS NP_387896.1 16077083 937037 complement(23146..23769) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11078735; Product type e: enzyme; deoxyguanosine kinase 23769 dgk 937037 dgk Bacillus subtilis subsp. subtilis str. 168 deoxyguanosine kinase NP_387896.1 23146 R 224308 CDS NP_387897.1 16077084 937029 complement(23868..25151) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 11737650, 12177332, 10419957; Product type e: enzyme; spore germination protein YaaH 25151 yaaH 937029 yaaH Bacillus subtilis subsp. subtilis str. 168 spore germination protein YaaH NP_387897.1 23868 R 224308 CDS NP_387898.1 16077085 937036 complement(25221..25766) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2521622; Product type pe : enzyme; isochorismatase 25766 yaaI 937036 yaaI Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_387898.1 25221 R 224308 CDS NP_387899.1 16077086 937989 25852..26337 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16700551; Product type e: enzyme; tRNA-specific adenosine deaminase 26337 tadA 937989 tadA Bacillus subtilis subsp. subtilis str. 168 tRNA-specific adenosine deaminase NP_387899.1 25852 D 224308 CDS NP_387900.2 255767015 936899 26814..28505 1 NC_000964.3 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunit gamma/tau 28505 dnaX 936899 dnaX Bacillus subtilis subsp. subtilis str. 168 DNA polymerase III subunit gamma/tau NP_387900.2 26814 D 224308 CDS NP_387901.1 16077088 937027 28529..28852 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16740939; Product type f: factor; nucleoid-associated protein YaaK 28852 yaaK 937027 yaaK Bacillus subtilis subsp. subtilis str. 168 nucleoid-associated protein YaaK NP_387901.1 28529 D 224308 CDS NP_387902.1 16077089 937197 28867..29463 1 NC_000964.3 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 29463 recR 937197 recR Bacillus subtilis subsp. subtilis str. 168 recombination protein RecR NP_387902.1 28867 D 224308 CDS NP_387903.1 16077090 937026 29481..29705 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 29705 yaaL 937026 yaaL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387903.1 29481 D 224308 CDS NP_387904.2 255767016 937025 29772..30035 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15087499; Product type r: regulator; sigma-K factor-processing regulator BofA 30035 bofA 937025 bofA Bacillus subtilis subsp. subtilis str. 168 sigma-K factor-processing regulator BofA NP_387904.2 29772 D 224308 CDS NP_387905.1 16077092 937016 35531..35725 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 8759874; Product type cp: cell process; sporulation protein CsfB 35725 csfB 937016 csfB Bacillus subtilis subsp. subtilis str. 168 sporulation protein CsfB NP_387905.1 35531 D 224308 CDS NP_387906.1 16077093 937019 35845..36459 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 5-bromo 4-chloroindolyl phosphate hydrolysis protein XpaC 36459 xpaC 937019 xpaC Bacillus subtilis subsp. subtilis str. 168 5-bromo 4-chloroindolyl phosphate hydrolysis protein XpaC NP_387906.1 35845 D 224308 CDS NP_387907.1 16077094 936551 36478..37638 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12533473; hypothetical protein 37638 yaaN 936551 yaaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387907.1 36478 D 224308 CDS NP_387908.1 16077095 937013 37720..39162 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9723923; Product type pe : enzyme; hypothetical protein 39162 yaaO 937013 yaaO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387908.1 37720 D 224308 CDS NP_387909.2 255767017 937018 39159..39797 1 NC_000964.3 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 39797 tmk 937018 tmk Bacillus subtilis subsp. subtilis str. 168 thymidylate kinase NP_387909.2 39159 D 224308 CDS NP_387910.1 16077097 938610 39871..40200 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913081; hypothetical protein 40200 yaaQ 938610 yaaQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387910.1 39871 D 224308 CDS NP_387911.1 16077098 936756 40213..40653 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 40653 yaaR 936756 yaaR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387911.1 40213 D 224308 CDS NP_387912.1 16077099 935949 40665..41654 1 NC_000964.3 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; DNA polymerase III subunit delta' 41654 holB 935949 holB Bacillus subtilis subsp. subtilis str. 168 DNA polymerase III subunit delta' NP_387912.1 40665 D 224308 CDS NP_387913.1 16077100 937012 41657..42484 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12270811; stage 0 sporulation protein YaaT 42484 yaaT 937012 yaaT Bacillus subtilis subsp. subtilis str. 168 stage 0 sporulation protein YaaT NP_387913.1 41657 D 224308 CDS NP_387914.1 16077101 937008 42499..42858 1 NC_000964.3 in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; initiation-control protein YabA 42858 yabA 937008 yabA Bacillus subtilis subsp. subtilis str. 168 initiation-control protein YabA NP_387914.1 42499 D 224308 CDS NP_387915.1 16077102 937011 42917..43660 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 43660 yabB 937011 yabB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387915.1 42917 D 224308 CDS NP_387916.1 16077103 937002 43647..43946 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11483577; Product type pe : enzyme; hypothetical protein 43946 yazA 937002 yazA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387916.1 43647 D 224308 CDS NP_387917.1 16077104 937010 43921..44799 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; ribosomal RNA small subunit methyltransferase I 44799 yabC 937010 yabC Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase I NP_387917.1 43921 D 224308 CDS NP_387918.1 16077105 937009 complement(44848..45138) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 16223496, 16702211, 10754235, 10809710, 11101881, 11101897; Product type r: regulator; transition state regulatory protein AbrB 45138 abrB 937009 abrB Bacillus subtilis subsp. subtilis str. 168 transition state regulatory protein AbrB NP_387918.1 44848 R 224308 CDS NP_387919.1 16077106 936877 45633..47627 1 NC_000964.3 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionine--tRNA ligase 47627 metS 936877 metS Bacillus subtilis subsp. subtilis str. 168 methionine--tRNA ligase NP_387919.1 45633 D 224308 CDS NP_387920.1 16077107 936949 47706..48473 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10747959, 16014871; Product type e: enzyme; deoxyribonuclease YabD 48473 yabD 936949 yabD Bacillus subtilis subsp. subtilis str. 168 deoxyribonuclease YabD NP_387920.1 47706 D 224308 CDS NP_387921.1 16077108 936891 48629..49942 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001, 19047346; Product type pe: enzyme; hypothetical protein 49942 yabE 936891 yabE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387921.1 48629 D 224308 CDS NP_387922.1 16077109 937001 50087..50647 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11233981, 11976317, 12794188, 16077031; Product type e: enzyme; ribonuclease M5 50647 rnmV 937001 rnmV Bacillus subtilis subsp. subtilis str. 168 ribonuclease M5 NP_387922.1 50087 D 224308 CDS NP_387923.1 16077110 936358 50640..51518 1 NC_000964.3 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; ribosomal RNA small subunit methyltransferase A 51518 ksgA 936358 ksgA Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase A NP_387923.1 50640 D 224308 CDS NP_387924.1 16077111 937005 51680..52552 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 11040425, 16751597, 19060142; Product type cp: cell process; sporulation-specific protease YabG 52552 yabG 937005 yabG Bacillus subtilis subsp. subtilis str. 168 sporulation-specific protease YabG NP_387924.1 51680 D 224308 CDS NP_387925.1 16077112 936744 52763..53023 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12761295; protein Veg 53023 veg 936744 veg Bacillus subtilis subsp. subtilis str. 168 protein Veg NP_387925.1 52763 D 224308 CDS NP_387926.1 16077113 936996 53183..53368 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11092849, 7959056, 8982008; Product type cp: cell process; small acid-soluble spore protein SspF 53368 sspF 936996 sspF Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein SspF NP_387926.1 53183 D 224308 CDS NP_387927.1 16077114 936970 53516..54385 1 NC_000964.3 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-c-methyl-d-erythritol kinase 54385 ipk 936970 ipk Bacillus subtilis subsp. subtilis str. 168 4-diphosphocytidyl-2-c-methyl-d-erythritol kinase NP_387927.1 53516 D 224308 CDS NP_387928.1 16077115 937000 54441..55298 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12837783, 12837784, 15629952, 16163456; Product type r: regulator; Pur operon repressor 55298 purR 937000 purR Bacillus subtilis subsp. subtilis str. 168 Pur operon repressor NP_387928.1 54441 D 224308 CDS NP_387929.1 16077116 936988 55295..55672 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12515541, 14729707, 10557275, 10919400, 10368157; Product type pe: enzyme; enamine/imine deaminase 55672 yabJ 936988 yabJ Bacillus subtilis subsp. subtilis str. 168 enamine/imine deaminase NP_387929.1 55295 D 224308 CDS NP_387930.1 16077117 936959 55866..56159 1 NC_000964.3 stage V sporulation protein G; essential for spore formation and a negative regulator of asymmetric septation in Bacillus; involved in methicillin-resistance, biofilm formation and capsular polysaccharide synthesis in Staphylococcus; septation protein SpoVG 56159 spoVG 936959 spoVG Bacillus subtilis subsp. subtilis str. 168 septation protein SpoVG NP_387930.1 55866 D 224308 CDS NP_387931.1 16077118 936139 56352..57722 1 NC_000964.3 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 57722 glmU 936139 glmU Bacillus subtilis subsp. subtilis str. 168 bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase NP_387931.1 56352 D 224308 CDS NP_387932.1 16077119 936985 57745..58698 1 NC_000964.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 58698 prs 936985 prs Bacillus subtilis subsp. subtilis str. 168 ribose-phosphate pyrophosphokinase NP_387932.1 57745 D 224308 CDS NP_387933.1 16077120 936984 58783..59397 1 NC_000964.3 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; general stress protein CTC 59397 ctc 936984 ctc Bacillus subtilis subsp. subtilis str. 168 general stress protein CTC NP_387933.1 58783 D 224308 CDS NP_387934.1 16077121 936740 59504..60070 1 NC_000964.3 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 60070 pth 936740 pth Bacillus subtilis subsp. subtilis str. 168 peptidyl-tRNA hydrolase NP_387934.1 59504 D 224308 CDS NP_387935.1 16077122 936978 60130..60360 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 60360 yabK 936978 yabK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387935.1 60130 D 224308 CDS NP_387936.1 16077123 936653 60430..63963 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 16950921, 8594198, 9535092; Product type f: factor; transcription-repair-coupling factor 63963 mfd 936653 mfd Bacillus subtilis subsp. subtilis str. 168 transcription-repair-coupling factor NP_387936.1 60430 D 224308 CDS NP_387937.1 16077124 936975 64099..64635 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15063493, 15939023, 16159768, 18996130, 8755877; Product type r: regulator; stage V sporulation protein T 64635 spoVT 936975 spoVT Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein T NP_387937.1 64099 D 224308 CDS NP_387938.1 16077125 936539 64817..66415 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 66415 yabM 936539 yabM Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_387938.1 64817 D 224308 CDS NP_387939.1 16077126 936973 66405..67874 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11178267; Product type pe : enzyme; hypothetical protein 67874 yabN 936973 yabN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387939.1 66405 D 224308 CDS NP_387940.1 16077127 936800 67877..68137 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10675343, 10675344; Product type pf: factor; hypothetical protein 68137 yabO 936800 yabO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387940.1 67877 D 224308 CDS NP_387941.1 16077128 936966 68216..68518 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15231775, 10869437; Product type f: factor; spore protein YabP 68518 yabP 936966 yabP Bacillus subtilis subsp. subtilis str. 168 spore protein YabP NP_387941.1 68216 D 224308 CDS NP_387942.1 16077129 936971 68515..69150 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 15849754, 16850406, 10869437; Product type f: factor; spore protein YabQ 69150 yabQ 936971 yabQ Bacillus subtilis subsp. subtilis str. 168 spore protein YabQ NP_387942.1 68515 D 224308 CDS NP_387943.1 16077130 936786 69168..69545 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11283287, 11994149, 12682299, 16936019; Product type f: factor; cell division protein DivIC 69545 divIC 936786 divIC Bacillus subtilis subsp. subtilis str. 168 cell division protein DivIC NP_387943.1 69168 D 224308 CDS NP_387944.1 16077131 936574 69626..70012 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066026, 16014871, 9862121; Product type pe: enzyme; hypothetical protein 70012 yabR 936574 yabR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387944.1 69626 D 224308 CDS NP_387945.1 16077132 938480 70538..73021 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10747015, 12180929, 15126482, 15866939, 15978076; Product type e: enzyme; stage II sporulation protein E 73021 spoIIE 938480 spoIIE Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein E NP_387945.1 70538 D 224308 CDS NP_387946.1 16077133 936965 73106..73843 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 73843 yabS 936965 yabS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387946.1 73106 D 224308 CDS NP_387947.2 50812174 936964 73809..74825 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase 74825 yabT 936964 yabT Bacillus subtilis subsp. subtilis str. 168 serine/threonine protein kinase NP_387947.2 73809 D 224308 CDS NP_387948.1 16077135 936922 74929..76347 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14527414, 16039592, 17005971; Product type e: enzyme; tRNA(ile)-lysidine synthase 76347 tilS 936922 tilS Bacillus subtilis subsp. subtilis str. 168 tRNA(ile)-lysidine synthase NP_387948.1 74929 D 224308 CDS NP_387949.1 16077136 936945 76344..76886 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 3110131, 6408059; Product type e: enzyme; hypoxanthine-guanine phosphoribosyltransferase 76886 hprT 936945 hprT Bacillus subtilis subsp. subtilis str. 168 hypoxanthine-guanine phosphoribosyltransferase NP_387949.1 76344 D 224308 CDS NP_387950.1 16077137 938094 76984..78897 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10851010, 10913836, 12533473, 9076729, 9084181, 9287010, 9352926; Product type e: enzyme; ATP-dependent zinc metalloprotease FtsH 78897 ftsH 938094 ftsH Bacillus subtilis subsp. subtilis str. 168 ATP-dependent zinc metalloprotease FtsH NP_387950.1 76984 D 224308 CDS NP_387951.2 255767018 936960 79092..79868 1 NC_000964.3 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; type III pantothenate kinase 79868 coaX 936960 coaX Bacillus subtilis subsp. subtilis str. 168 type III pantothenate kinase NP_387951.2 79092 D 224308 CDS NP_387952.1 16077139 936762 79880..80755 1 NC_000964.3 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; 33 kDa chaperonin 80755 hslO 936762 hslO Bacillus subtilis subsp. subtilis str. 168 33 kDa chaperonin NP_387952.1 79880 D 224308 CDS NP_387953.1 16077140 936955 80802..81695 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182, 15856219; Product type pf: factor; peptidyl-prolyl cis-trans isomerase 81695 yacD 936955 yacD Bacillus subtilis subsp. subtilis str. 168 peptidyl-prolyl cis-trans isomerase NP_387953.1 80802 D 224308 CDS NP_387954.1 16077141 936636 81771..82697 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 16267287, 16513748; Product type e: enzyme; cysteine synthase 82697 cysK 936636 cysK Bacillus subtilis subsp. subtilis str. 168 cysteine synthase NP_387954.1 81771 D 224308 CDS NP_387955.1 16077142 936926 82864..84276 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16605270, 17114263, 2123867, 9084182; Product type e: enzyme; para-aminobenzoate synthase component 1 84276 pabB 936926 pabB Bacillus subtilis subsp. subtilis str. 168 para-aminobenzoate synthase component 1 NP_387955.1 82864 D 224308 CDS NP_387956.1 16077143 936441 84290..84874 1 NC_000964.3 amphibolic enzyme subunit from Bacillus subtilis performs both in anthranilate and para-aminobenzoate synthesis; para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II 84874 pabA 936441 pabA Bacillus subtilis subsp. subtilis str. 168 para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II NP_387956.1 84290 D 224308 CDS NP_387957.1 16077144 936944 84874..85755 1 NC_000964.3 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate; aminodeoxychorismate lyase 85755 pabC 936944 pabC Bacillus subtilis subsp. subtilis str. 168 aminodeoxychorismate lyase NP_387957.1 84874 D 224308 CDS NP_387958.1 16077145 936256 85737..86594 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11007651, 2123867; Product type e: enzyme; dihydropteroate synthase 86594 sul 936256 sul Bacillus subtilis subsp. subtilis str. 168 dihydropteroate synthase NP_387958.1 85737 D 224308 CDS NP_387959.1 16077146 937976 86587..86949 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16188473, 17176045, 17388809; Product type e : enzyme; dihydroneopterin aldolase 86949 folB 937976 folB Bacillus subtilis subsp. subtilis str. 168 dihydroneopterin aldolase NP_387959.1 86587 D 224308 CDS NP_387960.1 16077147 936940 86946..87449 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17029412; Product type e: enzyme; 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase 87449 folK 936940 folK Bacillus subtilis subsp. subtilis str. 168 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase NP_387960.1 86946 D 224308 CDS NP_387961.1 16077148 936295 87401..87610 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 87610 yazB 936295 yazB Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_387961.1 87401 D 224308 CDS NP_387962.1 16077149 936924 87634..88635 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710, 15698474; Product type e: enzyme; tRNA-dihydrouridine synthase 88635 dusB 936924 dusB Bacillus subtilis subsp. subtilis str. 168 tRNA-dihydrouridine synthase NP_387962.1 87634 D 224308 CDS NP_387963.1 16077150 936911 88727..90226 1 NC_000964.3 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysine--tRNA ligase 90226 lysS 936911 lysS Bacillus subtilis subsp. subtilis str. 168 lysine--tRNA ligase NP_387963.1 88727 D 224308 CDS NP_387964.1 16077151 936883 101449..101913 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069659, 12618461, 16163393, 9852015; Product type r: regulator; transcriptional regulator CtsR 101913 ctsR 936883 ctsR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator CtsR NP_387964.1 101449 D 224308 CDS NP_387965.1 16077152 936845 101927..102484 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16163393; Product type f: factor; hypothetical protein 102484 mcsA 936845 mcsA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387965.1 101927 D 224308 CDS NP_387966.1 16077153 936939 102484..103575 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16163393, 17380125; Product type e: enzyme; ATP:guanido phosphotransferase YacI 103575 mcsB 936939 mcsB Bacillus subtilis subsp. subtilis str. 168 ATP:guanido phosphotransferase YacI NP_387966.1 102484 D 224308 CDS NP_387967.1 16077154 938481 103572..106004 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354604, 15529410, 16525504; Product type f: factor; negative regulator of genetic competence ClpC/MecB 106004 clpC 938481 clpC Bacillus subtilis subsp. subtilis str. 168 negative regulator of genetic competence ClpC/MecB NP_387967.1 103572 D 224308 CDS NP_387968.1 16077155 936872 106096..107472 1 NC_000964.3 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 107472 radA 936872 radA Bacillus subtilis subsp. subtilis str. 168 DNA repair protein RadA NP_387968.1 106096 D 224308 CDS NP_387969.1 16077156 936868 107476..108558 1 NC_000964.3 non-specific DNA-binding; scans chromosomes during sporulation for DNA-damage; delays initiation of sporulation; participates in a checkpoint signaling cascade for cell-cycle progression and DNA repair; DNA integrity scanning protein DisA 108558 yacK 936868 yacK Bacillus subtilis subsp. subtilis str. 168 DNA integrity scanning protein DisA NP_387969.1 107476 D 224308 CDS NP_387970.1 16077157 936863 108674..109774 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; PIN and TRAM-domain containing protein YacL 109774 yacL 936863 yacL Bacillus subtilis subsp. subtilis str. 168 PIN and TRAM-domain containing protein YacL NP_387970.1 108674 D 224308 CDS NP_387971.1 16077158 936855 109789..110487 1 NC_000964.3 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-D-methyl-D-erythritol 4-phosphate cytidylyltransferase 110487 ispD 936855 ispD Bacillus subtilis subsp. subtilis str. 168 2-D-methyl-D-erythritol 4-phosphate cytidylyltransferase NP_387971.1 109789 D 224308 CDS NP_387972.1 16077159 936634 110480..110956 1 NC_000964.3 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate; 2-D-methyl-D-erythritol 2,4-cyclodiphosphate synthase 110956 ispF 936634 ispF Bacillus subtilis subsp. subtilis str. 168 2-D-methyl-D-erythritol 2,4-cyclodiphosphate synthase NP_387972.1 110480 D 224308 CDS NP_387973.1 16077160 936862 111047..112498 1 NC_000964.3 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamate--tRNA ligase 112498 gltX 936862 gltX Bacillus subtilis subsp. subtilis str. 168 glutamate--tRNA ligase NP_387973.1 111047 D 224308 CDS NP_387974.1 16077161 936831 112800..113453 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751, 10737181, 7510287; Product type e: enzyme; serine acetyltransferase 113453 cysE 936831 cysE Bacillus subtilis subsp. subtilis str. 168 serine acetyltransferase NP_387974.1 112800 D 224308 CDS NP_387975.1 16077162 936859 113450..114850 1 NC_000964.3 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteine--tRNA ligase 114850 cysS 936859 cysS Bacillus subtilis subsp. subtilis str. 168 cysteine--tRNA ligase NP_387975.1 113450 D 224308 CDS NP_387976.1 16077163 936369 114854..115285 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871; Product type e: enzyme; mini-ribonuclease 3 115285 mrnC 936369 mrnC Bacillus subtilis subsp. subtilis str. 168 mini-ribonuclease 3 NP_387976.1 114854 D 224308 CDS NP_387977.1 16077164 936861 115269..116018 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11698387, 16014871; Product type e: enzyme; tRNA/rRNA methyltransferase TrmH 116018 rlmB 936861 rlmB Bacillus subtilis subsp. subtilis str. 168 tRNA/rRNA methyltransferase TrmH NP_387977.1 115269 D 224308 CDS NP_387978.1 16077165 936993 116025..116537 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114934; Product type pe : enzyme; hypothetical protein 116537 yacP 936993 yacP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387978.1 116025 D 224308 CDS NP_387979.1 16077166 936150 116600..117256 1 NC_000964.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; RNA polymerase sigma-H factor 117256 sigH 936150 sigH Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-H factor NP_387979.1 116600 D 224308 CDS NP_387980.1 16077167 936842 117349..117498 1 NC_000964.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group have the CXXC motif; 50S ribosomal protein L33 2 117498 rpmG 936842 rpmG Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L33 2 NP_387980.1 117349 D 224308 CDS NP_387981.1 16077168 936856 117532..117711 1 NC_000964.3 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 117711 secE 936856 secE Bacillus subtilis subsp. subtilis str. 168 preprotein translocase subunit SecE NP_387981.1 117532 D 224308 CDS NP_387982.1 16077169 936851 117890..118423 1 NC_000964.3 Modulates Rho-dependent transcription termination; transcription termination/antitermination protein NusG 118423 nusG 936851 nusG Bacillus subtilis subsp. subtilis str. 168 transcription termination/antitermination protein NusG NP_387982.1 117890 D 224308 CDS NP_387983.2 255767019 936838 118591..119016 1 NC_000964.3 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 119016 rplK 936838 rplK Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L11 NP_387983.2 118591 D 224308 CDS NP_387984.2 255767020 936843 119111..119809 1 NC_000964.3 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 119809 rplA 936843 rplA Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L1 NP_387984.2 119111 D 224308 CDS NP_387985.2 255767021 936153 120061..120561 1 NC_000964.3 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 120561 rplJ 936153 rplJ Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L10 NP_387985.2 120061 D 224308 CDS NP_387986.1 16077173 935952 120607..120978 1 NC_000964.3 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 120978 rplL 935952 rplL Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L7/L12 NP_387986.1 120607 D 224308 CDS NP_387987.1 16077174 938465 121068..121673 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17010380; Product type e: enzyme; hypothetical protein 121673 ybxB 938465 ybxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_387987.1 121068 D 224308 CDS NP_387988.2 255767022 936335 121919..125500 1 NC_000964.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 125500 rpoB 936335 rpoB Bacillus subtilis subsp. subtilis str. 168 DNA-directed RNA polymerase subunit beta NP_387988.2 121919 D 224308 CDS NP_387989.2 255767023 935977 125562..129161 1 NC_000964.3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' 129161 rpoC 935977 rpoC Bacillus subtilis subsp. subtilis str. 168 DNA-directed RNA polymerase subunit beta' NP_387989.2 125562 D 224308 CDS NP_387990.1 16077177 936829 129340..129588 1 NC_000964.3 in Bacillus subtilis this non-essential protein associates with the ribosome; ribosome-associated protein L7Ae-like 129588 ybxF 936829 ybxF Bacillus subtilis subsp. subtilis str. 168 ribosome-associated protein L7Ae-like NP_387990.1 129340 D 224308 CDS NP_387991.2 255767024 936616 129702..130118 1 NC_000964.3 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 130118 rpsL 936616 rpsL Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S12 NP_387991.2 129702 D 224308 CDS NP_387992.2 255767025 935997 130160..130630 1 NC_000964.3 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 130630 rpsG 935997 rpsG Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S7 NP_387992.2 130160 D 224308 CDS NP_387993.2 255767026 936826 130684..132762 1 NC_000964.3 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 132762 fusA 936826 fusA Bacillus subtilis subsp. subtilis str. 168 elongation factor G NP_387993.2 130684 D 224308 CDS NP_387994.1 16077181 935965 132882..134072 1 NC_000964.3 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 134072 tufA 935965 tufA Bacillus subtilis subsp. subtilis str. 168 elongation factor Tu NP_387994.1 132882 D 224308 CDS NP_387995.2 255767027 936866 134171..135127 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase YbaC 135127 ybaC 936866 ybaC Bacillus subtilis subsp. subtilis str. 168 aminopeptidase YbaC NP_387995.2 134171 D 224308 CDS NP_387996.1 16077183 936825 135364..135672 1 NC_000964.3 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 135672 rpsJ 936825 rpsJ Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S10 NP_387996.1 135364 D 224308 CDS NP_387997.1 16077184 936239 135712..136341 1 NC_000964.3 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 136341 rplC 936239 rplC Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L3 NP_387997.1 135712 D 224308 CDS NP_387998.1 16077185 936690 136369..136992 1 NC_000964.3 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 136992 rplD 936690 rplD Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L4 NP_387998.1 136369 D 224308 CDS NP_387999.2 255767028 936820 136992..137279 1 NC_000964.3 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 137279 rplW 936820 rplW Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L23 NP_387999.2 136992 D 224308 CDS NP_388000.2 255767029 936817 137311..138144 1 NC_000964.3 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 138144 rplB 936817 rplB Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L2 NP_388000.2 137311 D 224308 CDS NP_388001.1 16077188 936818 138202..138480 1 NC_000964.3 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 138480 rpsS 936818 rpsS Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S19 NP_388001.1 138202 D 224308 CDS NP_388002.1 16077189 938123 138497..138838 1 NC_000964.3 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 138838 rplV 938123 rplV Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L22 NP_388002.1 138497 D 224308 CDS NP_388003.2 255767030 936808 138842..139498 1 NC_000964.3 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 139498 rpsC 936808 rpsC Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S3 NP_388003.2 138842 D 224308 CDS NP_388004.1 16077191 936807 139500..139934 1 NC_000964.3 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 139934 rplP 936807 rplP Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L16 NP_388004.1 139500 D 224308 CDS NP_388005.1 16077192 936801 139924..140124 1 NC_000964.3 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 140124 rpmC 936801 rpmC Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L29 NP_388005.1 139924 D 224308 CDS NP_388006.1 16077193 936805 140147..140410 1 NC_000964.3 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 140410 rpsQ 936805 rpsQ Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S17 NP_388006.1 140147 D 224308 CDS NP_388007.1 16077194 935939 140451..140819 1 NC_000964.3 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 140819 rplN 935939 rplN Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L14 NP_388007.1 140451 D 224308 CDS NP_388008.1 16077195 936799 140857..141168 1 NC_000964.3 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 141168 rplX 936799 rplX Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L24 NP_388008.1 140857 D 224308 CDS NP_388009.1 16077196 936981 141195..141734 1 NC_000964.3 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 141734 rplE 936981 rplE Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L5 NP_388009.1 141195 D 224308 CDS NP_388010.1 16077197 935946 141757..141942 1 NC_000964.3 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group appear to contain the zinc-binding motif; 30S ribosomal protein S14 141942 rpsN 935946 rpsN Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S14 NP_388010.1 141757 D 224308 CDS NP_388011.2 255767031 936328 141974..142372 1 NC_000964.3 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 142372 rpsH 936328 rpsH Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S8 NP_388011.2 141974 D 224308 CDS NP_388012.1 16077199 938229 142402..142941 1 NC_000964.3 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 142941 rplF 938229 rplF Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L6 NP_388012.1 142402 D 224308 CDS NP_388013.2 255767032 936785 142974..143336 1 NC_000964.3 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 143336 rplR 936785 rplR Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L18 NP_388013.2 142974 D 224308 CDS NP_388014.1 16077201 938012 143361..143861 1 NC_000964.3 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 143861 rpsE 938012 rpsE Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S5 NP_388014.1 143361 D 224308 CDS NP_388015.1 16077202 936920 143875..144054 1 NC_000964.3 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 144054 rpmD 936920 rpmD Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L30 NP_388015.1 143875 D 224308 CDS NP_388016.1 16077203 935940 144085..144525 1 NC_000964.3 late assembly protein; 50S ribosomal protein L15 144525 rplO 935940 rplO Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L15 NP_388016.1 144085 D 224308 CDS NP_388017.1 16077204 936779 144527..145822 1 NC_000964.3 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; protein translocase subunit SecY 145822 secY 936779 secY Bacillus subtilis subsp. subtilis str. 168 protein translocase subunit SecY NP_388017.1 144527 D 224308 CDS NP_388018.1 16077205 938508 145877..146530 1 NC_000964.3 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 146530 adk 938508 adk Bacillus subtilis subsp. subtilis str. 168 adenylate kinase NP_388018.1 145877 D 224308 CDS NP_388019.1 16077206 938929 146527..147273 1 NC_000964.3 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 1 147273 mapA 938929 mapA Bacillus subtilis subsp. subtilis str. 168 methionine aminopeptidase 1 NP_388019.1 146527 D 224308 CDS YP_003097669.1 255767033 8303095 147312..147536 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17157877; Product type pf : factor; ribosome-binding protein YbzG 147536 ybzG 8303095 ybzG Bacillus subtilis subsp. subtilis str. 168 ribosome-binding protein YbzG YP_003097669.1 147312 D 224308 CDS NP_388020.1 16077207 938924 147585..147803 1 NC_000964.3 stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 147803 infA 938924 infA Bacillus subtilis subsp. subtilis str. 168 translation initiation factor IF-1 NP_388020.1 147585 D 224308 CDS NP_388021.1 16077208 938927 147837..147950 1 NC_000964.3 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif; 50S ribosomal protein L36 147950 rpmJ 938927 rpmJ Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L36 NP_388021.1 147837 D 224308 CDS NP_388022.2 255767034 938928 147973..148338 1 NC_000964.3 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 148338 rpsM 938928 rpsM Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S13 NP_388022.2 147973 D 224308 CDS NP_388023.1 16077210 938926 148359..148754 1 NC_000964.3 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 148754 rpsK 938926 rpsK Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S11 NP_388023.1 148359 D 224308 CDS NP_388024.1 16077211 938921 148931..149875 1 NC_000964.3 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 149875 rpoA 938921 rpoA Bacillus subtilis subsp. subtilis str. 168 DNA-directed RNA polymerase subunit alpha NP_388024.1 148931 D 224308 CDS NP_388025.1 16077212 938918 149953..150315 1 NC_000964.3 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 150315 rplQ 938918 rplQ Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L17 NP_388025.1 149953 D 224308 CDS NP_388026.2 255767035 938925 150443..151288 1 NC_000964.3 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene; energy-coupling factor transporter ATP-binding protein EcfA1 151288 cbiO 938925 cbiO Bacillus subtilis subsp. subtilis str. 168 energy-coupling factor transporter ATP-binding protein EcfA1 NP_388026.2 150443 D 224308 CDS NP_388027.1 16077214 938922 151303..152133 1 NC_000964.3 with CbiNQ forms the ABC transporter for cobalt import; Bacillus spp. have two adjacent copies of this gene; energy-coupling factor transporter ATP-binding protein EcfA2 152133 cbiO 938922 cbiO Bacillus subtilis subsp. subtilis str. 168 energy-coupling factor transporter ATP-binding protein EcfA2 NP_388027.1 151303 D 224308 CDS NP_388028.2 255767036 938923 152130..152927 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; energy-coupling factor transporter transmembrane protein EcfT 152927 ybaF 938923 ybaF Bacillus subtilis subsp. subtilis str. 168 energy-coupling factor transporter transmembrane protein EcfT NP_388028.2 152130 D 224308 CDS NP_388029.2 255767037 938920 152937..153680 1 NC_000964.3 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 153680 truA 938920 truA Bacillus subtilis subsp. subtilis str. 168 tRNA pseudouridine synthase A NP_388029.2 152937 D 224308 CDS NP_388030.2 255767038 938915 153842..154279 1 NC_000964.3 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 154279 rplM 938915 rplM Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L13 NP_388030.2 153842 D 224308 CDS NP_388031.1 16077218 938912 154300..154692 1 NC_000964.3 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 154692 rpsI 938912 rpsI Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S9 NP_388031.1 154300 D 224308 CDS NP_388032.2 255767039 938919 155156..155923 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 155923 ybaJ 938919 ybaJ Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_388032.2 155156 D 224308 CDS NP_388033.1 16077220 938916 156109..156552 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227, 16267290; Product type pe: enzyme; hypothetical protein 156552 ybaK 938916 ybaK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388033.1 156109 D 224308 CDS NP_388034.1 16077221 938917 156612..157325 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 16267290; Product type e: enzyme; germination-specific N-acetylmuramoyl-L-alanine amidase 157325 cwlD 938917 cwlD Bacillus subtilis subsp. subtilis str. 168 germination-specific N-acetylmuramoyl-L-alanine amidase NP_388034.1 156612 D 224308 CDS NP_388035.1 16077222 938914 157421..158479 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11790741, 15126467; Product type r: regulator; protein mrp homolog SalA 158479 salA 938914 salA Bacillus subtilis subsp. subtilis str. 168 protein mrp homolog SalA NP_388035.1 157421 D 224308 CDS NP_388036.1 16077223 938910 complement(158515..159072) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17122337, 10618233, 10376819; Product type f: factor; spore germination protein GerD 159072 gerD 938910 gerD Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerD NP_388036.1 158515 R 224308 CDS NP_388037.1 16077224 938913 159182..159778 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8576055; Product type r: regulator; kinB-signaling pathway activation protein 159778 kbaA 938913 kbaA Bacillus subtilis subsp. subtilis str. 168 kinB-signaling pathway activation protein NP_388037.1 159182 D 224308 CDS NP_388038.1 16077225 938911 complement(159779..160543) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 15547282; Product type ph: phenotype; polysaccharide deacetylase PdaB 160543 ybaN 938911 ybaN Bacillus subtilis subsp. subtilis str. 168 polysaccharide deacetylase PdaB NP_388038.1 159779 R 224308 CDS NP_388039.1 16077226 938890 177083..178519 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type m: membrane component; sulfate transporter YbaR 178519 ybaR 938890 ybaR Bacillus subtilis subsp. subtilis str. 168 sulfate transporter YbaR NP_388039.1 177083 D 224308 CDS NP_388040.2 255767040 938892 178665..179585 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 179585 ybaS 938892 ybaS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388040.2 178665 D 224308 CDS NP_388041.2 255767041 938887 complement(179595..180347) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 2974033; Product type pe: enzyme; hypothetical protein 180347 ybbA 938887 ybbA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388041.2 179595 R 224308 CDS NP_388042.2 255767042 938893 complement(180344..181354) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter; iron-uptake system permease protein FeuC 181354 feuC 938893 feuC Bacillus subtilis subsp. subtilis str. 168 iron-uptake system permease protein FeuC NP_388042.2 180344 R 224308 CDS NP_388043.1 16077230 938884 complement(181347..182351) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 2651410; Product type t : transporter; iron-uptake system permease protein FeuB 182351 feuB 938884 feuB Bacillus subtilis subsp. subtilis str. 168 iron-uptake system permease protein FeuB NP_388043.1 181347 R 224308 CDS NP_388044.1 16077231 938891 complement(182370..183323) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8388528; Product type lp: lipoprotein; iron-uptake system-binding protein 183323 feuA 938891 feuA Bacillus subtilis subsp. subtilis str. 168 iron-uptake system-binding protein NP_388044.1 182370 R 224308 CDS NP_388045.1 16077232 938888 complement(183414..185003) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 185003 ybbB 938888 ybbB Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388045.1 183414 R 224308 CDS NP_388046.1 16077233 938889 complement(185194..186438) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 186438 ybbC 938889 ybbC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388046.1 185194 R 224308 CDS NP_388047.1 16077234 938881 complement(186452..188380) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8063094; Product type pe : enzyme; lipoprotein 188380 ybbD 938881 ybbD Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388047.1 186452 R 224308 CDS NP_388048.2 255767043 938886 complement(188408..189733) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16452451; Product type pe : enzyme; hypothetical protein 189733 ybbE 938886 ybbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388048.2 188408 R 224308 CDS NP_388049.3 255767044 938879 complement(189790..191157) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 10627040; Product type pt: transporter; PTS system EIIBC component YbbF 191157 ybbF 938879 ybbF Bacillus subtilis subsp. subtilis str. 168 PTS system EIIBC component YbbF NP_388049.3 189790 R 224308 CDS NP_388050.1 16077237 938885 complement(191183..192034) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; RpiR family transcriptional regulator 192034 ybbH 938885 ybbH Bacillus subtilis subsp. subtilis str. 168 RpiR family transcriptional regulator NP_388050.1 191183 R 224308 CDS NP_388051.1 16077238 938882 complement(192051..192965) 1 NC_000964.3 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway; N-acetylmuramic acid 6-phosphate etherase 192965 murQ 938882 murQ Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramic acid 6-phosphate etherase NP_388051.1 192051 R 224308 CDS NP_388052.2 255767045 938883 complement(193075..193557) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YbbJ 193557 ybbJ 938883 ybbJ Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YbbJ NP_388052.2 193075 R 224308 CDS NP_388053.2 255767046 938877 complement(193570..194025) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 194025 ybbK 938877 ybbK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388053.2 193570 R 224308 CDS NP_388054.1 16077241 938868 194849..195412 1 NC_000964.3 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription: this protein is involved in detoxification and protection against antimicrobial; RNA polymerase sigma factor SigW 195412 sigW 938868 sigW Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigW NP_388054.1 194849 D 224308 CDS NP_388055.1 16077242 938876 195426..196052 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127; Product type r: regulator; anti-sigma-W factor RsiW 196052 rsiW 938876 rsiW Bacillus subtilis subsp. subtilis str. 168 anti-sigma-W factor RsiW NP_388055.1 195426 D 224308 CDS NP_388056.2 255767047 938735 196213..197034 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 197034 ybbP 938735 ybbP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388056.2 196213 D 224308 CDS NP_388057.2 255767048 938867 197027..198478 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16236721; YbbR-like domain-containing protein YbbR 198478 ybbR 938867 ybbR Bacillus subtilis subsp. subtilis str. 168 YbbR-like domain-containing protein YbbR NP_388057.2 197027 D 224308 CDS NP_388058.1 16077245 938632 198497..199843 1 NC_000964.3 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase 199843 glmM 938632 glmM Bacillus subtilis subsp. subtilis str. 168 phosphoglucosamine mutase NP_388058.1 198497 D 224308 CDS NP_388059.1 16077246 938736 200277..202079 1 NC_000964.3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glutamine--fructose-6-phosphate aminotransferase 202079 glmS 938736 glmS Bacillus subtilis subsp. subtilis str. 168 glutamine--fructose-6-phosphate aminotransferase NP_388059.1 200277 D 224308 CDS NP_388061.1 16077248 938586 complement(202547..203458) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7565865, 8376346; Product type e: enzyme; DNA-3-methyladenine glycosylase 203458 alkA 938586 alkA Bacillus subtilis subsp. subtilis str. 168 DNA-3-methyladenine glycosylase NP_388061.1 202547 R 224308 CDS NP_388062.1 16077249 938648 203729..204364 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme; bifunctional transcriptional activator/DNA repair enzyme AdaA 204364 adaA 938648 adaA Bacillus subtilis subsp. subtilis str. 168 bifunctional transcriptional activator/DNA repair enzyme AdaA NP_388062.1 203729 D 224308 CDS NP_388063.1 16077250 938673 204351..204890 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744039, 2120677, 7565865, 8376346; Product type e: enzyme; methylated-dna--protein-cysteine methyltransferase 204890 adaB 938673 adaB Bacillus subtilis subsp. subtilis str. 168 methylated-dna--protein-cysteine methyltransferase NP_388063.1 204351 D 224308 CDS NP_388064.1 16077251 938593 205409..206926 1 NC_000964.3 Catalyzes the transfer of electrons from NADH to ubiquinone; NADH-quinone oxidoreductase subunit 5 206926 ndhF 938593 ndhF Bacillus subtilis subsp. subtilis str. 168 NADH-quinone oxidoreductase subunit 5 NP_388064.1 205409 D 224308 CDS NP_388065.2 255767049 938603 206941..209556 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 209556 ybcC 938603 ybcC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388065.2 206941 D 224308 CDS NP_388067.1 16077254 938524 209633..210160 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carbonic anhydrase-like protein YbcF 210160 ybcF 938524 ybcF Bacillus subtilis subsp. subtilis str. 168 carbonic anhydrase-like protein YbcF NP_388067.1 209633 D 224308 CDS NP_388068.1 16077255 938573 210224..210514 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 210514 ybcH 938573 ybcH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388068.1 210224 D 224308 CDS NP_388069.1 16077256 938568 210572..210946 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 210946 ybcI 938568 ybcI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388069.1 210572 D 224308 CDS YP_003097670.1 255767050 8302965 211429..211731 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 211731 ybzH 8302965 ybzH Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator YP_003097670.1 211429 D 224308 CDS NP_388070.1 16077257 938536 211859..213031 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15812018, 15849754, 16850406; Product type pt: transporter; MFS transporter 213031 ybcL 938536 ybcL Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388070.1 211859 D 224308 CDS NP_388071.1 16077258 938504 213155..213469 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 213469 ybcM 938504 ybcM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388071.1 213155 D 224308 CDS NP_388072.1 16077259 938506 213941..214108 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type f: factor; sporulation-killing factor SkfA 214108 skfA 938506 skfA Bacillus subtilis subsp. subtilis str. 168 sporulation-killing factor SkfA NP_388072.1 213941 D 224308 CDS NP_388073.2 50812176 938501 214175..215407 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776, 18307109; Product type f: factor; hypothetical protein 215407 skfB 938501 skfB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388073.2 214175 D 224308 CDS YP_003097671.1 255767051 8302931 215404..216894 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter; sporulation-killing factor biosynthesis protein SkfC 216894 skfC 8302931 skfC Bacillus subtilis subsp. subtilis str. 168 sporulation-killing factor biosynthesis protein SkfC YP_003097671.1 215404 D 224308 CDS NP_388077.1 16077264 938498 216913..217632 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter; SkfA peptide export ATP-binding protein SkfE 217632 skfE 938498 skfE Bacillus subtilis subsp. subtilis str. 168 SkfA peptide export ATP-binding protein SkfE NP_388077.1 216913 D 224308 CDS NP_388078.2 255767052 938494 217697..219040 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 15849754, 16816204, 16850406, 17069462, 17184776; Product type t : transporter; bacteriocin-SkfA transport system permease SkfF 219040 skfF 938494 skfF Bacillus subtilis subsp. subtilis str. 168 bacteriocin-SkfA transport system permease SkfF NP_388078.2 217697 D 224308 CDS NP_388079.2 255767053 938502 219087..219602 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype; hypothetical protein 219602 skfG 938502 skfG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388079.2 219087 D 224308 CDS NP_388080.2 255767054 938499 219607..220032 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 16816204, 17069462, 17184776; Product type ph: phenotype; thioredoxin 220032 skfH 938499 skfH Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_388080.2 219607 D 224308 CDS NP_388081.2 255767055 938500 220279..221256 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 221256 ybdG 938500 ybdG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388081.2 220279 D 224308 CDS NP_388082.1 16077269 938485 221258..221929 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 221929 ybdJ 938485 ybdJ Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388082.1 221258 D 224308 CDS NP_388083.1 16077270 938496 221950..222912 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 222912 ybdK 938496 ybdK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388083.1 221950 D 224308 CDS YP_003097672.1 255767056 8303143 222971..223234 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 223234 ybzI 8303143 ybzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097672.1 222971 D 224308 CDS NP_388085.1 16077272 938464 complement(223219..223989) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase 223989 ybdM 938464 ybdM Bacillus subtilis subsp. subtilis str. 168 serine/threonine protein kinase NP_388085.1 223219 R 224308 CDS NP_388086.1 16077273 938489 complement(224075..224932) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16794953; Product type h : extrachromosomal origin; hypothetical protein 224932 ybdN 938489 ybdN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388086.1 224075 R 224308 CDS NP_388087.1 16077274 938493 225064..226248 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type h : extrachromosomal origin; hypothetical protein 226248 ybdO 938493 ybdO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388087.1 225064 D 224308 CDS NP_388088.1 16077275 938470 226566..227954 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 227954 ybxG 938470 ybxG Bacillus subtilis subsp. subtilis str. 168 transporter NP_388088.1 226566 D 224308 CDS NP_388089.1 16077276 938448 228066..228314 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9016963; Product type cp: cell process; sigma-G-dependent sporulation-specific SASP protein 228314 csgA 938448 csgA Bacillus subtilis subsp. subtilis str. 168 sigma-G-dependent sporulation-specific SASP protein NP_388089.1 228066 D 224308 CDS NP_388090.1 16077277 938445 228331..228522 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 228522 ybxH 938445 ybxH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388090.1 228331 D 224308 CDS NP_388091.1 16077278 938466 complement(228549..229352) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14742199; Product type e: enzyme; beta-lactamase YbxI 229352 ybxI 938466 ybxI Bacillus subtilis subsp. subtilis str. 168 beta-lactamase YbxI NP_388091.1 228549 R 224308 CDS NP_388092.1 16077279 938449 229525..230778 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10529095; Product type e: enzyme; fatty-acid peroxygenase 230778 cypC 938449 cypC Bacillus subtilis subsp. subtilis str. 168 fatty-acid peroxygenase NP_388092.1 229525 D 224308 CDS NP_388093.1 16077280 938450 complement(230819..231079) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 231079 ybyB 938450 ybyB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388093.1 230819 R 224308 CDS NP_388094.2 255767057 938442 231348..232967 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid-proton symporter YbeC 232967 ybeC 938442 ybeC Bacillus subtilis subsp. subtilis str. 168 amino acid-proton symporter YbeC NP_388094.2 231348 D 224308 CDS NP_388095.1 16077282 938446 complement(233014..233895) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081; Product type e: enzyme; glycerophosphoryl diester phosphodiesterase 233895 glpQ 938446 glpQ Bacillus subtilis subsp. subtilis str. 168 glycerophosphoryl diester phosphodiesterase NP_388095.1 233014 R 224308 CDS NP_388096.1 16077283 938447 complement(233994..235328) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406, 8012593; Product type t: transporter; glycerol-3-phosphate transporter 235328 glpT 938447 glpT Bacillus subtilis subsp. subtilis str. 168 glycerol-3-phosphate transporter NP_388096.1 233994 R 224308 CDS NP_388097.1 16077284 938444 235625..235873 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 235873 ybeF 938444 ybeF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388097.1 235625 D 224308 CDS NP_388098.1 16077285 938439 235965..236882 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; MarR family transcriptional regulator 236882 ybfA 938439 ybfA Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388098.1 235965 D 224308 CDS NP_388099.1 16077286 938436 236879..238129 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 238129 ybfB 938436 ybfB Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388099.1 236879 D 224308 CDS NP_388100.2 255767058 938443 complement(238164..238448) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 238448 ybfE 938443 ybfE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388100.2 238164 R 224308 CDS NP_388101.1 16077288 938441 complement(238644..239555) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 239555 ybfF 938441 ybfF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388101.1 238644 R 224308 CDS NP_388102.1 16077289 938433 complement(239644..241842) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 241842 ybfG 938433 ybfG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388102.1 239644 R 224308 CDS NP_388103.1 16077290 938440 complement(241917..242837) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 242837 ybfH 938440 ybfH Bacillus subtilis subsp. subtilis str. 168 transporter NP_388103.1 241917 R 224308 CDS NP_388104.1 16077291 938437 complement(242834..243661) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 243661 ybfI 938437 ybfI Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388104.1 242834 R 224308 CDS NP_388105.1 16077292 938438 243892..245046 1 NC_000964.3 non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis; phosphoribosylglycinamide formyltransferase 245046 purT 938438 purT Bacillus subtilis subsp. subtilis str. 168 phosphoribosylglycinamide formyltransferase NP_388105.1 243892 D 224308 CDS NP_388106.1 16077293 938430 245190..246131 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15375126; Product type e: enzyme; extracellular metalloprotease 246131 mpr 938430 mpr Bacillus subtilis subsp. subtilis str. 168 extracellular metalloprotease NP_388106.1 245190 D 224308 CDS NP_388107.1 16077294 938435 246094..246492 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 246492 ybfJ 938435 ybfJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388107.1 246094 D 224308 CDS NP_388108.1 16077295 938434 246658..247548 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11389736; Product type e: enzyme; carboxylesterase YbfK 247548 ybfK 938434 ybfK Bacillus subtilis subsp. subtilis str. 168 carboxylesterase YbfK NP_388108.1 246658 D 224308 CDS NP_388109.1 16077296 938427 247744..248277 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14762009, 15743965, 15849754, 16850406; Product type e: enzyme; CDP-diacylglycerol--serine O-phosphatidyltransferase 248277 pssA 938427 pssA Bacillus subtilis subsp. subtilis str. 168 CDP-diacylglycerol--serine O-phosphatidyltransferase NP_388109.1 247744 D 224308 CDS NP_388110.1 16077297 938432 248268..248756 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 14762009, 15849754, 16850406; Product type pe: enzyme; membrane protein 248756 ybfM 938432 ybfM Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388110.1 248268 D 224308 CDS NP_388111.1 16077298 938431 248749..249540 1 NC_000964.3 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine; phosphatidylserine decarboxylase proenzyme 249540 psd 938431 psd Bacillus subtilis subsp. subtilis str. 168 phosphatidylserine decarboxylase proenzyme NP_388111.1 248749 D 224308 CDS NP_388112.1 16077299 938429 249595..249873 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 249873 ybfN 938429 ybfN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388112.1 249595 D 224308 CDS NP_388113.1 16077300 938424 249979..251319 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YbfO 251319 ybfO 938424 ybfO Bacillus subtilis subsp. subtilis str. 168 hydrolase YbfO NP_388113.1 249979 D 224308 CDS NP_388114.1 16077301 938428 251427..252314 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 252314 ybfP 938428 ybfP Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388114.1 251427 D 224308 CDS NP_388115.1 16077302 938426 252514..253482 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme; hypothetical protein 253482 ybfQ 938426 ybfQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388115.1 252514 D 224308 CDS NP_388116.1 16077303 938421 complement(253518..254762) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7751298; Product type t: transporter; proton glutamate symport protein 254762 gltP 938421 gltP Bacillus subtilis subsp. subtilis str. 168 proton glutamate symport protein NP_388116.1 253518 R 224308 CDS NP_388117.1 16077304 938418 complement(254907..256802) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10627040, 15849754, 16850406; Product type t : transporter; PTS system glucosamine-specific EIICBA component 256802 nagP 938418 nagP Bacillus subtilis subsp. subtilis str. 168 PTS system glucosamine-specific EIICBA component NP_388117.1 254907 R 224308 CDS NP_388118.1 16077305 938425 complement(256823..257572) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; glucosamine-6-phosphate deaminase 2 257572 nagBB 938425 nagBB Bacillus subtilis subsp. subtilis str. 168 glucosamine-6-phosphate deaminase 2 NP_388118.1 256823 R 224308 CDS NP_388119.1 16077306 938422 257791..258498 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 258498 ybgA 938422 ybgA Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388119.1 257791 D 224308 CDS NP_388120.1 16077307 938423 258532..258807 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 12897008; membrane protein 258807 ybgB 938423 ybgB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388120.1 258532 D 224308 CDS NP_388121.1 16077308 938420 259016..260086 1 NC_000964.3 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain-amino acid transaminase 1 260086 ybgE 938420 ybgE Bacillus subtilis subsp. subtilis str. 168 branched-chain-amino acid transaminase 1 NP_388121.1 259016 D 224308 CDS NP_388122.1 16077309 938415 complement(260123..261535) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 7704263; Product type pt: transporter; amino acid permease YbgF 261535 ybgF 938415 ybgF Bacillus subtilis subsp. subtilis str. 168 amino acid permease YbgF NP_388122.1 260123 R 224308 CDS NP_388123.1 16077310 938412 complement(261656..262603) 1 NC_000964.3 converts homocysteine and S-adenosyl-methionine to methionine and S-adenosyl-homocysteine or S-methyl-methionine and homocysteine to two methionines; homocysteine S-methyltransferase YbgG 262603 mmuM 938412 mmuM Bacillus subtilis subsp. subtilis str. 168 homocysteine S-methyltransferase YbgG NP_388123.1 261656 R 224308 CDS NP_388124.2 255767059 938419 complement(262732..264168) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 15995196, 16850406; Product type t: transporter; sodium/glutamine symporter GlnT 264168 glnT 938419 glnT Bacillus subtilis subsp. subtilis str. 168 sodium/glutamine symporter GlnT NP_388124.2 262732 R 224308 CDS NP_388125.1 16077312 938416 complement(264191..265174) 1 NC_000964.3 catalyzes the formation of glutamate from glutamine; glutaminase 1 265174 ybgJ 938416 ybgJ Bacillus subtilis subsp. subtilis str. 168 glutaminase 1 NP_388125.1 264191 R 224308 CDS NP_388126.2 255767060 938417 265476..266708 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11717295, 15995196; Product type rc : receptor; sensor histidine kinase 266708 glnJ 938417 glnJ Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388126.2 265476 D 224308 CDS NP_388127.1 16077314 938414 266719..267663 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15995196; Product type r: regulator; transcriptional regulatory protein GlnL 267663 glnL 938414 glnL Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein GlnL NP_388127.1 266719 D 224308 CDS NP_388128.2 255767061 938409 267890..268816 1 NC_000964.3 catalyzes the formation of 2,5-dioxopentanoate from 5-dehydro-4-deoxy-D-glucarate; 5-dehydro-4-deoxyglucarate dehydratase 268816 ycbC 938409 ycbC Bacillus subtilis subsp. subtilis str. 168 5-dehydro-4-deoxyglucarate dehydratase NP_388128.2 267890 D 224308 CDS NP_388129.1 16077316 938406 268846..270312 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12044674, 17202142; Product type e: enzyme; aldehyde dehydrogenase YcbD 270312 ycbD 938406 ycbD Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase YcbD NP_388129.1 268846 D 224308 CDS NP_388130.2 255767062 938413 270396..271763 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674, 15849754, 16850406; Product type t: transporter; glucarate transporter 271763 gudP 938413 gudP Bacillus subtilis subsp. subtilis str. 168 glucarate transporter NP_388130.2 270396 D 224308 CDS NP_388131.2 255767063 938410 271800..273167 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type e: enzyme; glucarate dehydratase 273167 gudD 938410 gudD Bacillus subtilis subsp. subtilis str. 168 glucarate dehydratase NP_388131.2 271800 D 224308 CDS NP_388132.2 255767064 938411 273237..273938 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12044674; Product type r: regulator; GntR family transcriptional regulator 273938 ycbG 938411 ycbG Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388132.2 273237 D 224308 CDS NP_388133.2 255767065 938407 274029..275561 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 9772162; Product type e: enzyme; D-galactarate dehydratase 275561 garD 938407 garD Bacillus subtilis subsp. subtilis str. 168 D-galactarate dehydratase NP_388133.2 274029 D 224308 CDS NP_388134.1 16077321 938408 275838..276758 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12044674; Product type pe : enzyme; hypothetical protein 276758 ycbJ 938408 ycbJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388134.1 275838 D 224308 CDS NP_388135.1 16077322 938403 277160..277321 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10706627, 11557884, 12855807, 15099736, 15213402, 15743934, 16306262; Product type r: regulator; tryptophan RNA-binding attenuator protein inhibitory protein 277321 rtpA 938403 rtpA Bacillus subtilis subsp. subtilis str. 168 tryptophan RNA-binding attenuator protein inhibitory protein NP_388135.1 277160 D 224308 CDS NP_388136.1 16077323 938405 277342..278280 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10706627, 15063849, 15849754, 16850406, 16879415, 17114263; Product type pt : transporter; transporter 278280 ycbK 938405 ycbK Bacillus subtilis subsp. subtilis str. 168 transporter NP_388136.1 277342 D 224308 CDS NP_388137.2 255767066 938400 278377..279057 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 279057 ycbL 938400 ycbL Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388137.2 278377 D 224308 CDS NP_388138.2 255767067 938397 279059..279994 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 279994 ycbM 938397 ycbM Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388138.2 279059 D 224308 CDS NP_388139.2 255767068 938404 280086..281009 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040; Product type pt : transporter; ABC transporter ATP-binding protein 281009 ycbN 938404 ycbN Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388139.2 280086 D 224308 CDS NP_388140.3 255767069 938401 281028..281714 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 281714 ycbO 938401 ycbO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388140.3 281028 D 224308 CDS NP_388141.1 16077328 938402 complement(281769..282155) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 282155 ycbP 938402 ycbP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388141.1 281769 R 224308 CDS NP_388142.2 255767070 938399 282469..282897 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11466292, 11807087, 12177332, 16936016, 9515903; Product type e: enzyme; cell wall hydrolase CwlJ 282897 cwlJ 938399 cwlJ Bacillus subtilis subsp. subtilis str. 168 cell wall hydrolase CwlJ NP_388142.2 282469 D 224308 CDS NP_388143.2 255767071 938394 283003..283734 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 283734 ycbR 938394 ycbR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388143.2 283003 D 224308 CDS YP_003097673.1 255767072 8302909 283816..283992 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 283992 yczK 8302909 yczK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097673.1 283816 D 224308 CDS NP_388144.2 255767073 938391 284011..285762 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719524, 12867413, 16698798; Product type e: enzyme; alkaline phosphatase D 285762 phoD 938391 phoD Bacillus subtilis subsp. subtilis str. 168 alkaline phosphatase D NP_388144.2 284011 D 224308 CDS NP_388145.2 255767074 938398 285775..285987 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12867413, 15554971, 16678787, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatAd 285987 tatAD 938398 tatAD Bacillus subtilis subsp. subtilis str. 168 Sec-independent protein translocase protein TatAd NP_388145.2 285775 D 224308 CDS NP_388146.2 255767075 938395 286048..286776 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16698798, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatCd 286776 tatCD 938395 tatCD Bacillus subtilis subsp. subtilis str. 168 Sec-independent protein translocase protein TatCd NP_388146.2 286048 D 224308 CDS NP_388147.1 16077334 938396 complement(286773..287420) 1 NC_000964.3 catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 287420 pcp 938396 pcp Bacillus subtilis subsp. subtilis str. 168 pyrrolidone-carboxylate peptidase NP_388147.1 286773 R 224308 CDS NP_388148.2 255767076 938393 287499..288611 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminotransferase YcbU 288611 ycbU 938393 ycbU Bacillus subtilis subsp. subtilis str. 168 aminotransferase YcbU NP_388148.2 287499 D 224308 CDS NP_388149.1 16077336 938388 complement(288653..290092) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15317768, 15849754, 16850406; Product type t: transporter; lincomycin resistance protein LmrB 290092 lmrB 938388 lmrB Bacillus subtilis subsp. subtilis str. 168 lincomycin resistance protein LmrB NP_388149.1 288653 R 224308 CDS NP_388150.1 16077337 938385 complement(290132..290698) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12718394, 15317768, 17483215; Product type r: regulator; TetR family transcriptional regulator 290698 lmrA 938385 lmrA Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388150.1 290132 R 224308 CDS NP_388151.1 16077338 938392 290915..292042 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 17686772; Product type e: enzyme; asparaginase 292042 ansZ 938392 ansZ Bacillus subtilis subsp. subtilis str. 168 asparaginase NP_388151.1 290915 D 224308 CDS NP_388152.1 16077339 938389 292205..292843 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15812018, 18053819, 11029590, 8396026; Product type e: enzyme; lipase EstA 292843 estA 938389 estA Bacillus subtilis subsp. subtilis str. 168 lipase EstA NP_388152.1 292205 D 224308 CDS NP_388153.1 16077340 938390 complement(292881..293264) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 293264 yczC 938390 yczC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388153.1 292881 R 224308 CDS NP_388154.1 16077341 938387 293499..294575 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 294575 yccF 938387 yccF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388154.1 293499 D 224308 CDS NP_388155.1 16077342 938382 complement(294615..295571) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type rc: receptor; sensor histidine kinase 295571 natK 938382 natK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388155.1 294615 R 224308 CDS NP_388156.1 16077343 938379 complement(295584..296285) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17322186; Product type r: regulator; transcriptional regulator 296285 natR 938379 natR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388156.1 295584 R 224308 CDS NP_388157.1 16077344 938386 296429..297169 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 17322186; Product type t: transporter; ATP-binding transport protein NatA 297169 natA 938386 natA Bacillus subtilis subsp. subtilis str. 168 ATP-binding transport protein NatA NP_388157.1 296429 D 224308 CDS NP_388158.1 16077345 938383 297170..298330 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 17322186; Product type t: transporter; sodium efflux ABC transporter permease NatB 298330 natB 938383 natB Bacillus subtilis subsp. subtilis str. 168 sodium efflux ABC transporter permease NatB NP_388158.1 297170 D 224308 CDS NP_388159.1 16077346 938384 298466..299398 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17322186; Product type pe : enzyme; oxidoreductase 299398 yccK 938384 yccK Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388159.1 298466 D 224308 CDS NP_388160.1 16077347 938380 complement(299438..300502) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 300502 ycdA 938380 ycdA Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388160.1 299438 R 224308 CDS NP_388161.1 16077348 938381 300830..302248 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 302248 ycdB 938381 ycdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388161.1 300830 D 224308 CDS NP_388162.1 16077349 938376 302435..303796 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 303796 ycdC 938376 ycdC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388162.1 302435 D 224308 CDS NP_388163.1 16077350 938378 complement(303804..304307) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17588176; Product type e: enzyme; peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK 304307 cwlK 938378 cwlK Bacillus subtilis subsp. subtilis str. 168 peptidoglycan L-alanyl-D-glutamate endopeptidase CwlK NP_388163.1 303804 R 224308 CDS NP_388164.1 16077351 938373 304430..305551 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme; response regulator aspartate phosphatase J 305551 rapJ 938373 rapJ Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase J NP_388164.1 304430 D 224308 CDS NP_388165.1 16077352 938377 305658..306434 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme; glucose 1-dehydrogenase 2 306434 ycdF 938377 ycdF Bacillus subtilis subsp. subtilis str. 168 glucose 1-dehydrogenase 2 NP_388165.1 305658 D 224308 CDS NP_388166.1 16077353 938375 306459..308144 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544224; Product type pe : enzyme; oligo-1,6-glucosidase 2 308144 ycdG 938375 ycdG Bacillus subtilis subsp. subtilis str. 168 oligo-1,6-glucosidase 2 NP_388166.1 306459 D 224308 CDS NP_388167.1 16077354 938370 308332..309291 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12426338, 14730579, 9379902; Product type lp : lipoprotein; zinc transport system zinc-binding lipoprotein AdcA 309291 adcA 938370 adcA Bacillus subtilis subsp. subtilis str. 168 zinc transport system zinc-binding lipoprotein AdcA NP_388167.1 308332 D 224308 CDS NP_388168.1 16077355 938374 309347..310042 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9379902, 9811636; Product type t : transporter; zinc transport system ATP-binding protein AdcC 310042 adcC 938374 adcC Bacillus subtilis subsp. subtilis str. 168 zinc transport system ATP-binding protein AdcC NP_388168.1 309347 D 224308 CDS NP_388169.1 16077356 938367 310000..310842 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 9379902, 9811636; Product type t: transporter; zinc transport system permease protein AdcB 310842 adcB 938367 adcB Bacillus subtilis subsp. subtilis str. 168 zinc transport system permease protein AdcB NP_388169.1 310000 D 224308 CDS NP_388170.2 255767077 938371 complement(310880..311875) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16428414; Product type pe : enzyme; hypothetical protein 311875 yceB 938371 yceB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388170.2 310880 R 224308 CDS NP_388171.1 16077358 938372 312159..312758 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; stress response protein SCP2 312758 yceC 938372 yceC Bacillus subtilis subsp. subtilis str. 168 stress response protein SCP2 NP_388171.1 312159 D 224308 CDS NP_388172.1 16077359 938364 312780..313361 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; general stress protein 16U 313361 yceD 938364 yceD Bacillus subtilis subsp. subtilis str. 168 general stress protein 16U NP_388172.1 312780 D 224308 CDS NP_388173.1 16077360 938368 313396..313974 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 313974 yceE 938368 yceE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388173.1 313396 D 224308 CDS NP_388174.1 16077361 938369 314025..314798 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 314798 yceF 938369 yceF Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388174.1 314025 D 224308 CDS NP_388175.1 16077362 938361 314883..316496 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 316496 yceG 938361 yceG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388175.1 314883 D 224308 CDS NP_388176.1 16077363 938366 316512..317603 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 317603 yceH 938366 yceH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388176.1 316512 D 224308 CDS NP_388177.1 16077364 938365 317725..318927 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; niacin/nicotinamide transporter NaiP 318927 yceI 938365 yceI Bacillus subtilis subsp. subtilis str. 168 niacin/nicotinamide transporter NaiP NP_388177.1 317725 D 224308 CDS NP_388178.1 16077365 938363 complement(319180..320352) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 320352 yceJ 938363 yceJ Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388178.1 319180 R 224308 CDS NP_388179.1 16077366 938357 complement(320421..320723) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 320723 yceK 938357 yceK Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_388179.1 320421 R 224308 CDS NP_388180.2 255767078 938362 321013..322269 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type t: transporter; glycine/betaine ABC transporter ATP-binding protein 322269 opuAA 938362 opuAA Bacillus subtilis subsp. subtilis str. 168 glycine/betaine ABC transporter ATP-binding protein NP_388180.2 321013 D 224308 CDS NP_388181.1 16077368 938360 322271..323119 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16225868, 16645306, 16850406, 8752321; Product type t : transporter; glycine betaine transport system permease protein OpuAB 323119 opuAB 938360 opuAB Bacillus subtilis subsp. subtilis str. 168 glycine betaine transport system permease protein OpuAB NP_388181.1 322271 D 224308 CDS NP_388182.1 16077369 938354 323119..324000 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16225868, 16645306, 7622480; Product type lp: lipoprotein; glycine betaine-binding protein OpuAC 324000 opuAC 938354 opuAC Bacillus subtilis subsp. subtilis str. 168 glycine betaine-binding protein OpuAC NP_388182.1 323119 D 224308 CDS NP_388183.2 255767079 938351 complement(324038..325189) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8768514; Product type e : enzyme; amidohydrolase AmhX 325189 amhX 938351 amhX Bacillus subtilis subsp. subtilis str. 168 amidohydrolase AmhX NP_388183.2 324038 R 224308 CDS NP_388184.2 255767080 938359 325339..326772 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 326772 ycgA 938359 ycgA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388184.2 325339 D 224308 CDS NP_388185.2 255767081 938355 326888..327469 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 327469 ycgB 938355 ycgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388185.2 326888 D 224308 CDS NP_388186.2 255767082 938356 327618..329597 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3117969, 9353930; Product type e: enzyme; alpha-amylase 329597 amyE 938356 amyE Bacillus subtilis subsp. subtilis str. 168 alpha-amylase NP_388186.2 327618 D 224308 CDS NP_388187.2 255767083 938348 329774..330739 1 NC_000964.3 Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase 330739 ldh 938348 ldh Bacillus subtilis subsp. subtilis str. 168 L-lactate dehydrogenase NP_388187.2 329774 D 224308 CDS NP_388188.2 255767084 938353 330771..332396 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 15849754, 16428414, 16850406; Product type t: transporter; L-lactate permease 332396 lctP 938353 lctP Bacillus subtilis subsp. subtilis str. 168 L-lactate permease NP_388188.2 330771 D 224308 CDS NP_388189.2 255767085 938345 complement(332441..333979) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15489457, 15849754, 16850406, 9023234; Product type t: transporter; multidrug resistance protein 333979 mdr 938345 mdr Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_388189.2 332441 R 224308 CDS NP_388190.2 255767086 938352 334092..334556 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 334556 ycgE 938352 ycgE Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_388190.2 334092 D 224308 CDS NP_388191.1 16077378 938349 334630..335259 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid efflux protein YcgF 335259 ycgF 938349 ycgF Bacillus subtilis subsp. subtilis str. 168 amino acid efflux protein YcgF NP_388191.1 334630 D 224308 CDS NP_388192.2 255767087 938350 335329..336090 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 336090 ycgG 938350 ycgG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388192.2 335329 D 224308 CDS NP_388193.2 255767088 938347 complement(336092..337432) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 337432 ycgH 938347 ycgH Bacillus subtilis subsp. subtilis str. 168 transporter NP_388193.2 336092 R 224308 CDS NP_388194.3 255767089 938342 337562..338158 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16433904; Product type pe : enzyme; hypothetical protein 338158 ycgI 938342 ycgI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388194.3 337562 D 224308 CDS NP_388195.1 16077382 938339 338288..339106 1 NC_000964.3 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NH(3)-dependent NAD(+) synthetase 339106 nadE 938339 nadE Bacillus subtilis subsp. subtilis str. 168 NH(3)-dependent NAD(+) synthetase NP_388195.1 338288 D 224308 CDS NP_388196.2 255767090 938346 complement(339156..339749) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15131133, 1624425, 7766032; Product type f: factor; tunicamycin resistance protein 339749 tmrB 938346 tmrB Bacillus subtilis subsp. subtilis str. 168 tunicamycin resistance protein NP_388196.2 339156 R 224308 CDS NP_388197.2 255767091 938343 340025..340585 1 NC_000964.3 catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis; shikimate kinase 340585 aroK 938343 aroK Bacillus subtilis subsp. subtilis str. 168 shikimate kinase NP_388197.2 340025 D 224308 CDS NP_388198.2 255767092 938344 complement(340613..341374) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 341374 ycgJ 938344 ycgJ Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_388198.2 340613 R 224308 CDS NP_388199.2 255767093 938340 341492..342466 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pr : regulator; LysR family transcriptional regulator 342466 ycgK 938340 ycgK Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_388199.2 341492 D 224308 CDS NP_388200.1 16077387 938341 342538..343494 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12842474; Product type e: enzyme; cephalosporin-C deacetylase 343494 cah 938341 cah Bacillus subtilis subsp. subtilis str. 168 cephalosporin-C deacetylase NP_388200.1 342538 D 224308 CDS NP_388201.1 16077388 938336 343578..344360 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 344360 ycgL 938336 ycgL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388201.1 343578 D 224308 CDS NP_388202.1 16077389 938338 344551..345462 1 NC_000964.3 Evidence 1b: Function experimentally demonstrated in the studied species; PubMedId: 17536821, 2118500; Product type e: enzyme; proline dehydrogenase 2 345462 ycgM 938338 ycgM Bacillus subtilis subsp. subtilis str. 168 proline dehydrogenase 2 NP_388202.1 344551 D 224308 CDS NP_388203.2 255767094 938333 345479..347026 1 NC_000964.3 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase 2 347026 ycgN 938333 ycgN Bacillus subtilis subsp. subtilis str. 168 1-pyrroline-5-carboxylate dehydrogenase 2 NP_388203.2 345479 D 224308 CDS NP_388204.2 255767095 938330 347150..348571 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14976255, 15849754, 16850406; Product type pt: transporter; symporter 348571 ycgO 938330 ycgO Bacillus subtilis subsp. subtilis str. 168 symporter NP_388204.2 347150 D 224308 CDS NP_388205.2 255767096 938337 348724..349959 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 349959 ycgP 938337 ycgP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388205.2 348724 D 224308 CDS NP_388206.1 16077393 938334 complement(349996..350853) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 350853 ycgQ 938334 ycgQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388206.1 349996 R 224308 CDS NP_388207.1 16077394 938335 complement(350858..351742) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 351742 ycgR 938335 ycgR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388207.1 350858 R 224308 CDS NP_388208.1 16077395 938332 complement(351842..352696) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YcgS 352696 ycgS 938332 ycgS Bacillus subtilis subsp. subtilis str. 168 hydrolase YcgS NP_388208.1 351842 R 224308 CDS NP_388209.1 16077396 938327 352858..353868 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16672620; Product type pe : enzyme; ferredoxin--NADP reductase 1 353868 ycgT 938327 ycgT Bacillus subtilis subsp. subtilis str. 168 ferredoxin--NADP reductase 1 NP_388209.1 352858 D 224308 CDS NP_388210.1 16077397 938324 complement(353900..355351) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme; uroporphyrinogen-iii C-methyltransferase 355351 nasF 938324 nasF Bacillus subtilis subsp. subtilis str. 168 uroporphyrinogen-iii C-methyltransferase NP_388210.1 353900 R 224308 CDS NP_388211.1 16077398 938331 complement(355412..355732) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217486, 15028686, 9765565; Product type e: enzyme; assimilatory nitrite reductase [NAD(P)H] small subunit 355732 nasE 938331 nasE Bacillus subtilis subsp. subtilis str. 168 assimilatory nitrite reductase [NAD(P)H] small subunit NP_388211.1 355412 R 224308 CDS NP_388212.1 16077399 938329 complement(355764..358181) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme; nitrite reductase 358181 nasD 938329 nasD Bacillus subtilis subsp. subtilis str. 168 nitrite reductase NP_388212.1 355764 R 224308 CDS NP_388213.2 255767097 938321 complement(358303..360435) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 9765565; Product type e: enzyme; assimilatory nitrate reductase catalytic subunit 360435 nasC 938321 nasC Bacillus subtilis subsp. subtilis str. 168 assimilatory nitrate reductase catalytic subunit NP_388213.2 358303 R 224308 CDS NP_388214.2 255767098 938328 complement(360442..362757) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10940050, 10972836, 15028686, 7836289, 9765565; Product type e: enzyme; assimilatory nitrate reductase electron transfer subunit 362757 nasB 938328 nasB Bacillus subtilis subsp. subtilis str. 168 assimilatory nitrate reductase electron transfer subunit NP_388214.2 360442 R 224308 CDS NP_388215.2 255767099 938326 362937..364142 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7868621; Product type t: transporter; nitrate transporter 364142 nasA 938326 nasA Bacillus subtilis subsp. subtilis str. 168 nitrate transporter NP_388215.2 362937 D 224308 CDS NP_388216.2 255767100 938325 364259..365173 1 NC_000964.3 similar protein in Methanocaldococcus converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate as the first step in methanopterin biosynthesis; GTP cyclohydrolase folE2 365173 yciA 938325 yciA Bacillus subtilis subsp. subtilis str. 168 GTP cyclohydrolase folE2 NP_388216.2 364259 D 224308 CDS NP_388217.2 255767101 938318 365170..365754 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338; Product type pt : transporter; L,D-transpeptidase YciB 365754 yciB 938318 yciB Bacillus subtilis subsp. subtilis str. 168 L,D-transpeptidase YciB NP_388217.2 365170 D 224308 CDS YP_003097674.1 255767102 8303053 365850..366035 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 366035 yczL 8303053 yczL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097674.1 365850 D 224308 CDS NP_388218.1 16077405 938322 366063..367256 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12426338, 18344368, 2013568, 9811636; Product type pt: transporter; metal chaperone YciC 367256 yciC 938322 yciC Bacillus subtilis subsp. subtilis str. 168 metal chaperone YciC NP_388218.1 366063 D 224308 CDS NP_388219.1 16077406 938323 complement(367305..367985) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid ABC transporter permease protein YckA 367985 yckA 938323 yckA Bacillus subtilis subsp. subtilis str. 168 amino acid ABC transporter permease protein YckA NP_388219.1 367305 R 224308 CDS NP_388220.1 16077407 938320 complement(367995..368858) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter extracellular-binding protein YckB 368858 yckB 938320 yckB Bacillus subtilis subsp. subtilis str. 168 ABC transporter extracellular-binding protein YckB NP_388220.1 367995 R 224308 CDS NP_388221.1 16077408 938315 369236..369691 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 369691 yckC 938315 yckC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388221.1 369236 D 224308 CDS NP_388222.1 16077409 938319 369773..370105 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 370105 yckD 938319 yckD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388222.1 369773 D 224308 CDS NP_388223.1 16077410 938317 370259..371692 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18069788; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglC 371692 bglC 938317 bglC Bacillus subtilis subsp. subtilis str. 168 aryl-phospho-beta-d-glucosidase BglC NP_388223.1 370259 D 224308 CDS NP_388224.1 16077411 938312 complement(371729..372127) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663; Product type r: regulator; DNA-entry nuclease inhibitor 372127 nin 938312 nin Bacillus subtilis subsp. subtilis str. 168 DNA-entry nuclease inhibitor NP_388224.1 371729 R 224308 CDS NP_388225.2 50812179 938309 complement(372154..372597) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 11814663, 2841296, 7746143; Product type e: enzyme; DNA-entry nuclease 372597 nucA 938309 nucA Bacillus subtilis subsp. subtilis str. 168 DNA-entry nuclease NP_388225.2 372154 R 224308 CDS NP_388226.2 255767103 938316 complement(372771..374492) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187186, 7704255, 7921238; Product type rc : receptor; methyl-accepting chemotaxis protein TlpC 374492 tlpC 938316 tlpC Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein TlpC NP_388226.2 372771 R 224308 CDS NP_388227.1 16077414 938313 complement(374603..375160) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme; 3-hexulose-6-phosphate isomerase 375160 hxlB 938313 hxlB Bacillus subtilis subsp. subtilis str. 168 3-hexulose-6-phosphate isomerase NP_388227.1 374603 R 224308 CDS NP_388228.1 16077415 938314 complement(375166..375798) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572115, 15978081; Product type e: enzyme; 3-hexulose-6-phosphate synthase 375798 hxlA 938314 hxlA Bacillus subtilis subsp. subtilis str. 168 3-hexulose-6-phosphate synthase NP_388228.1 375166 R 224308 CDS NP_388229.2 255767104 938311 376032..376394 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15978081; Product type r: regulator; HxlR family transcriptional regulator 376394 hxlR 938311 hxlR Bacillus subtilis subsp. subtilis str. 168 HxlR family transcriptional regulator NP_388229.2 376032 D 224308 CDS NP_388230.2 255767105 938306 376968..387731 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 8288534, 8441623; Product type e: enzyme; surfactin synthase subunit 1 387731 srfAA 938306 srfAA Bacillus subtilis subsp. subtilis str. 168 surfactin synthase subunit 1 NP_388230.2 376968 D 224308 CDS NP_388231.2 255767106 938303 387744..398495 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase subunit 2 398495 srfAB 938303 srfAB Bacillus subtilis subsp. subtilis str. 168 surfactin synthase subunit 2 NP_388231.2 387744 D 224308 CDS NP_388232.1 16077419 938310 390880..391020 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10361283, 16554821, 8752331, 9696775; Product type r: regulator; competence protein S 391020 comS 938310 comS Bacillus subtilis subsp. subtilis str. 168 competence protein S NP_388232.1 390880 D 224308 CDS NP_388233.2 255767107 938308 398532..402359 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase subunit 3 402359 srfAC 938308 srfAC Bacillus subtilis subsp. subtilis str. 168 surfactin synthase subunit 3 NP_388233.2 398532 D 224308 CDS NP_388234.1 16077421 938300 402388..403116 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16166527, 16553878, 17227471; Product type e: enzyme; surfactin synthase thioesterase subunit 403116 srfAD 938300 srfAD Bacillus subtilis subsp. subtilis str. 168 surfactin synthase thioesterase subunit NP_388234.1 402388 D 224308 CDS NP_388235.2 255767108 938307 403217..404443 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 404443 ycxA 938307 ycxA Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388235.2 403217 D 224308 CDS NP_388236.1 16077423 938305 complement(404458..405015) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 405015 ycxB 938305 ycxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388236.1 404458 R 224308 CDS NP_388237.2 255767109 938297 complement(405069..406007) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 406007 ycxC 938297 ycxC Bacillus subtilis subsp. subtilis str. 168 transporter NP_388237.2 405069 R 224308 CDS NP_388238.1 16077425 938304 406131..407465 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 407465 ycxD 938304 ycxD Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388238.1 406131 D 224308 CDS NP_388240.2 255767110 938302 complement(408240..408887) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 17827323; Product type m : membrane component; membrane protein 408887 yczE 938302 yczE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388240.2 408240 R 224308 CDS NP_388241.2 255767111 938294 complement(409208..409951) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter; L-cystine import ATP-binding protein TcyC 409951 tcyC 938294 tcyC Bacillus subtilis subsp. subtilis str. 168 L-cystine import ATP-binding protein TcyC NP_388241.2 409208 R 224308 CDS NP_388242.1 16077428 938301 complement(409965..410669) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter; L-cystine transport system permease protein TcyB 410669 tcyB 938301 tcyB Bacillus subtilis subsp. subtilis str. 168 L-cystine transport system permease protein TcyB NP_388242.1 409965 R 224308 CDS NP_388243.2 255767112 938298 complement(410656..411462) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924; Product type t: transporter; L-cystine-binding protein TcyA 411462 tcyA 938298 tcyA Bacillus subtilis subsp. subtilis str. 168 L-cystine-binding protein TcyA NP_388243.2 410656 R 224308 CDS NP_388244.1 16077430 938299 complement(411578..412450) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator 412450 yclA 938299 yclA Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_388244.1 411578 R 224308 CDS NP_388245.1 16077431 938296 412540..413154 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10919793; Product type pe : enzyme; phenolic acid decarboxylase subunit B 413154 yclB 938296 yclB Bacillus subtilis subsp. subtilis str. 168 phenolic acid decarboxylase subunit B NP_388245.1 412540 D 224308 CDS NP_388246.1 16077432 938291 413157..414578 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11029449, 18388975; Product type pe: enzyme; phenolic acid decarboxylase subunit C 414578 ubiD 938291 ubiD Bacillus subtilis subsp. subtilis str. 168 phenolic acid decarboxylase subunit C NP_388246.1 413157 D 224308 CDS YP_003097675.1 255767113 8302940 414595..414822 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15979273, 18388975; Product type e: enzyme; phenolic acid decarboxylase subunit D 414822 bsdD 8302940 bsdD Bacillus subtilis subsp. subtilis str. 168 phenolic acid decarboxylase subunit D YP_003097675.1 414595 D 224308 CDS NP_388247.2 255767114 938293 414819..415283 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15979273; Product type pe : enzyme; hypothetical protein 415283 yclD 938293 yclD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388247.2 414819 D 224308 CDS NP_388248.2 255767115 938288 415350..416195 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YclE 416195 yclE 938288 yclE Bacillus subtilis subsp. subtilis str. 168 AB hydrolase superfamily protein YclE NP_388248.2 415350 D 224308 CDS NP_388249.2 255767116 938295 complement(416235..417713) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717292, 15849754, 16850406, 8458848; Product type t: transporter; transporter 417713 dtpT 938295 dtpT Bacillus subtilis subsp. subtilis str. 168 transporter NP_388249.2 416235 R 224308 CDS NP_388250.1 16077436 938292 417993..419747 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 419747 yclG 938292 yclG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388250.1 417993 D 224308 CDS NP_388251.1 16077437 938290 complement(419763..419984) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 419984 yczF 938290 yczF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388251.1 419763 R 224308 CDS NP_388252.1 16077438 938285 420110..421744 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process; spore germination protein KA 421744 gerKA 938285 gerKA Bacillus subtilis subsp. subtilis str. 168 spore germination protein KA NP_388252.1 420110 D 224308 CDS NP_388253.1 16077439 938287 421734..422957 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 16707705, 16740944; Product type cp: cell process; spore germination protein KC 422957 gerKC 938287 gerKC Bacillus subtilis subsp. subtilis str. 168 spore germination protein KC NP_388253.1 421734 D 224308 CDS NP_388254.1 16077440 938282 422982..424103 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10762253, 15849754, 16707705, 16740944, 16850406; Product type cp: cell process; spore germination protein KB 424103 gerKB 938282 gerKB Bacillus subtilis subsp. subtilis str. 168 spore germination protein KB NP_388254.1 422982 D 224308 CDS NP_388255.1 16077441 938289 complement(424208..424888) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 424888 yclH 938289 yclH Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388255.1 424208 R 224308 CDS NP_388256.2 255767117 938279 complement(424904..426364) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter permease 426364 yclI 938279 yclI Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_388256.2 424904 R 224308 CDS NP_388257.1 16077443 938286 426577..427260 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type r: regulator; transcriptional regulator 427260 yclJ 938286 yclJ Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388257.1 426577 D 224308 CDS NP_388258.1 16077444 938283 427247..428668 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15375128; Product type rc: receptor; sensor histidine kinase 428668 yclK 938283 yclK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388258.1 427247 D 224308 CDS NP_388259.1 16077445 938284 428831..429979 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917; Product type e: enzyme; response regulator aspartate phosphatase C 429979 rapC 938284 rapC Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase C NP_388259.1 428831 D 224308 CDS NP_388260.1 16077446 938281 429963..430085 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464187, 12456319, 12897006, 12950917, 16816200; Product type r: regulator; phosphatase RapC inhibitor 430085 phrC 938281 phrC Bacillus subtilis subsp. subtilis str. 168 phosphatase RapC inhibitor NP_388260.1 429963 D 224308 CDS YP_003097677.1 255767119 8302990 complement(430356..430469) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 430469 yczN 8302990 yczN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097677.1 430356 R 224308 CDS NP_388261.1 16077447 938276 complement(430623..431987) 1 NC_000964.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartokinase 3 431987 yclM 938276 yclM Bacillus subtilis subsp. subtilis str. 168 aspartokinase 3 NP_388261.1 430623 R 224308 CDS NP_388262.1 16077448 938273 432372..433322 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 433322 yclN 938273 yclN Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_388262.1 432372 D 224308 CDS NP_388263.1 16077449 938280 433315..434262 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 434262 yclO 938280 yclO Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_388263.1 433315 D 224308 CDS NP_388264.1 16077450 938278 434256..435014 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter ATP-binding protein 435014 yclP 938278 yclP Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388264.1 434256 D 224308 CDS NP_388265.1 16077451 938277 435036..435989 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter substrate-binding protein 435989 yclQ 938277 yclQ Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein NP_388265.1 435036 D 224308 CDS NP_388266.1 16077452 938275 complement(436036..437454) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 437454 ycnB 938275 ycnB Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388266.1 436036 R 224308 CDS NP_388267.2 255767120 938270 complement(437474..438352) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 438352 ycnC 938270 ycnC Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388267.2 437474 R 224308 CDS NP_388268.1 16077454 938267 complement(438516..439265) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16229462, 9836433; Product type e: enzyme; FMN reductase 439265 ycnD 938267 ycnD Bacillus subtilis subsp. subtilis str. 168 FMN reductase NP_388268.1 438516 R 224308 CDS NP_388269.1 16077455 938274 complement(439282..439569) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; monooxygenase YcnE 439569 ycnE 938274 ycnE Bacillus subtilis subsp. subtilis str. 168 monooxygenase YcnE NP_388269.1 439282 R 224308 CDS NP_388270.1 16077456 938272 439709..440023 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 440023 yczG 938272 yczG Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_388270.1 439709 D 224308 CDS NP_388271.1 16077457 938271 complement(440025..441464) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311; Product type r: regulator; GntR family transcriptional regulator 441464 gabR 938271 gabR Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388271.1 440025 R 224308 CDS NP_388272.1 16077458 938264 441571..442881 1 NC_000964.3 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate; 4-aminobutyrate aminotransferase 442881 gabT 938264 gabT Bacillus subtilis subsp. subtilis str. 168 4-aminobutyrate aminotransferase NP_388272.1 441571 D 224308 CDS NP_388273.1 16077459 939976 442950..444338 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 15590624, 9723923; Product type e : enzyme; succinate-semialdehyde dehydrogenase 444338 gabD 939976 gabD Bacillus subtilis subsp. subtilis str. 168 succinate-semialdehyde dehydrogenase NP_388273.1 442950 D 224308 CDS NP_388274.1 16077460 938268 444461..445324 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438764, 15849754, 16850406; Product type t : transporter; glucose uptake protein GlcU 445324 glcU 938268 glcU Bacillus subtilis subsp. subtilis str. 168 glucose uptake protein GlcU NP_388274.1 444461 D 224308 CDS NP_388275.1 16077461 938261 445344..446129 1 NC_000964.3 Converts glucose to D-glucono-1,5 lactone; glucose 1-dehydrogenase 446129 gdh 938261 gdh Bacillus subtilis subsp. subtilis str. 168 glucose 1-dehydrogenase NP_388275.1 445344 D 224308 CDS NP_388276.1 16077462 938266 complement(446174..446788) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 446788 ycnI 938266 ycnI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388276.1 446174 R 224308 CDS NP_388277.2 255767121 938258 complement(446801..448426) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter; copper transport protein YcnJ 448426 ycnJ 938258 ycnJ Bacillus subtilis subsp. subtilis str. 168 copper transport protein YcnJ NP_388277.2 446801 R 224308 CDS NP_388278.1 16077464 938265 complement(448461..449033) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pr : regulator; DeoR family transcriptional regulator 449033 ycnK 938265 ycnK Bacillus subtilis subsp. subtilis str. 168 DeoR family transcriptional regulator NP_388278.1 448461 R 224308 CDS NP_388279.1 16077465 939465 449198..449551 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 18307109; Product type pe: enzyme; hypothetical protein 449551 ycnL 939465 ycnL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388279.1 449198 D 224308 CDS NP_388280.2 255767122 938263 449724..451160 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter; PTS system mannitol-specific EIICB component 451160 mtlA 938263 mtlA Bacillus subtilis subsp. subtilis str. 168 PTS system mannitol-specific EIICB component NP_388280.2 449724 D 224308 CDS YP_003097678.1 255767123 8303136 451185..451616 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type t: transporter; mannitol-specific phosphotransferase enzyme IIA component 451616 mtlF 8303136 mtlF Bacillus subtilis subsp. subtilis str. 168 mannitol-specific phosphotransferase enzyme IIA component YP_003097678.1 451185 D 224308 CDS NP_388281.2 255767124 939968 451618..452739 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme; mannitol-1-phosphate 5-dehydrogenase 452739 mtlD 939968 mtlD Bacillus subtilis subsp. subtilis str. 168 mannitol-1-phosphate 5-dehydrogenase NP_388281.2 451618 D 224308 CDS NP_388282.3 255767125 938262 452830..453894 1 NC_000964.3 catalyzes the formation of oxaloglycolate from tartrate; also catalyzes the formation of pyruvate from malate and glycerate from tartrate; tartrate dehydrogenase/decarboxylase 453894 ycsA 938262 ycsA Bacillus subtilis subsp. subtilis str. 168 tartrate dehydrogenase/decarboxylase NP_388282.3 452830 D 224308 CDS NP_388283.1 16077469 939966 454029..454592 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14568161, 9325333; Product type e: enzyme; signal peptidase I U 454592 sipU 939966 sipU Bacillus subtilis subsp. subtilis str. 168 signal peptidase I U NP_388283.1 454029 D 224308 CDS NP_388284.2 255767126 938255 complement(454652..455260) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase 455260 yczH 938255 yczH Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_388284.2 454652 R 224308 CDS NP_388285.2 50812182 938260 455346..455738 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16291680; Product type pe: enzyme; hypothetical protein 455738 ycsD 938260 ycsD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388285.2 455346 D 224308 CDS YP_003097679.1 255767127 8302943 complement(455771..455935) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 455935 yczO 8302943 yczO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097679.1 455771 R 224308 CDS NP_388286.2 255767128 938252 456068..456817 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 456817 ycsE 938252 ycsE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388286.2 456068 D 224308 CDS NP_388287.3 255767129 938259 457023..457796 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme; hypothetical protein 457796 ycsF 938259 ycsF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388287.3 457023 D 224308 CDS NP_388288.3 255767130 938257 457811..459025 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9334321; Product type pt: transporter; membrane protein 459025 ycsG 938257 ycsG Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388288.3 457811 D 224308 CDS NP_388289.3 255767131 938647 459049..459822 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9334321; hypothetical protein 459822 ycsI 938647 ycsI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388289.3 459049 D 224308 CDS NP_388290.2 50812186 938256 459867..460589 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pf : factor; kinase A inhibitor 460589 kipI 938256 kipI Bacillus subtilis subsp. subtilis str. 168 kinase A inhibitor NP_388290.2 459867 D 224308 CDS YP_054571.2 255767132 2914204 460592..461599 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9334321; Product type pe : enzyme; kipi antagonist 461599 kipA 2914204 kipA Bacillus subtilis subsp. subtilis str. 168 kipi antagonist YP_054571.2 460592 D 224308 CDS NP_388291.2 255767133 939999 461615..462367 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9334321; Product type r: regulator; IclR family transcriptional regulator 462367 kipR 939999 kipR Bacillus subtilis subsp. subtilis str. 168 IclR family transcriptional regulator NP_388291.2 461615 D 224308 CDS NP_388292.1 16077478 938249 462431..463072 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17220230, 9334321; Product type e: enzyme; spore germination lipase LipC 463072 lipC 938249 lipC Bacillus subtilis subsp. subtilis str. 168 spore germination lipase LipC NP_388292.1 462431 D 224308 CDS NP_388293.1 16077479 939989 463245..463490 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 463490 yczI 939989 yczI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388293.1 463245 D 224308 CDS NP_388294.1 16077480 938254 complement(463496..463783) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 463783 yczJ 938254 yczJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388294.1 463496 R 224308 CDS NP_388295.1 16077481 940139 463934..465940 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8830698; Product type lp: lipoprotein; penicillin-binding protein 3 465940 pbpC 940139 pbpC Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 3 NP_388295.1 463934 D 224308 CDS NP_388296.1 16077482 936168 466042..466944 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 466944 ycsN 936168 ycsN Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388296.1 466042 D 224308 CDS NP_388297.1 16077483 938253 467130..469214 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type r: regulator; transcriptional regulator MtlR 469214 mtlR 938253 mtlR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator MtlR NP_388297.1 467130 D 224308 CDS NP_388298.2 255767134 938246 469426..470937 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl--CoA ligase YdaB 470937 ydaB 938246 ydaB Bacillus subtilis subsp. subtilis str. 168 acyl--CoA ligase YdaB NP_388298.2 469426 D 224308 CDS NP_388299.1 16077485 940142 complement(470957..471502) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 471502 ydaC 940142 ydaC Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_388299.1 470957 R 224308 CDS NP_388300.1 16077486 938251 471709..472569 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 11948145; Product type pe: enzyme; general stress protein 39 472569 ydaD 938251 ydaD Bacillus subtilis subsp. subtilis str. 168 general stress protein 39 NP_388300.1 471709 D 224308 CDS NP_388301.1 16077487 938182 472585..473088 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10220166; D-lyxose ketol-isomerase 473088 ydaE 938182 ydaE Bacillus subtilis subsp. subtilis str. 168 D-lyxose ketol-isomerase NP_388301.1 472585 D 224308 CDS NP_388302.1 16077488 938250 473174..473725 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15468321; Product type pe : enzyme; ribosomal N-acetyltransferase YdaF 473725 ydaF 938250 ydaF Bacillus subtilis subsp. subtilis str. 168 ribosomal N-acetyltransferase YdaF NP_388302.1 473174 D 224308 CDS NP_388303.1 16077489 939958 473803..474225 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor; general stress protein 26 474225 ydaG 939958 ydaG Bacillus subtilis subsp. subtilis str. 168 general stress protein 26 NP_388303.1 473803 D 224308 CDS NP_388304.1 16077490 938243 474731..475540 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 475540 ydaH 938243 ydaH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388304.1 474731 D 224308 CDS NP_388305.1 16077491 938248 complement(475584..475874) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 475874 ydzA 938248 ydzA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388305.1 475584 R 224308 CDS NP_388306.1 16077492 940147 476059..476493 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10606655, 10913073, 12458218, 16407330, 16528101, 9341680; Product type r : regulator; AsnC family transcriptional regulator 476493 lrpC 940147 lrpC Bacillus subtilis subsp. subtilis str. 168 AsnC family transcriptional regulator NP_388306.1 476059 D 224308 CDS NP_388307.1 16077493 938247 476558..478741 1 NC_000964.3 decatenates replicating daughter chromosomes; DNA topoisomerase 3 478741 topB 938247 topB Bacillus subtilis subsp. subtilis str. 168 DNA topoisomerase 3 NP_388307.1 476558 D 224308 CDS NP_388308.1 16077494 938245 478944..480032 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 480032 ydaJ 938245 ydaJ Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388308.1 478944 D 224308 CDS NP_388309.1 16077495 938240 480013..480864 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 480864 ydaK 938240 ydaK Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388309.1 480013 D 224308 CDS NP_388310.1 16077496 938244 480875..482584 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 482584 ydaL 938244 ydaL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388310.1 480875 D 224308 CDS NP_388311.1 16077497 939986 482577..483839 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YdaM 483839 ydaM 939986 ydaM Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YdaM NP_388311.1 482577 D 224308 CDS NP_388312.1 16077498 940004 483845..485956 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 485956 ydaN 940004 ydaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388312.1 483845 D 224308 CDS NP_388313.1 16077499 938237 486432..488255 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter; amino acid permease YdaO 488255 ydaO 938237 ydaO Bacillus subtilis subsp. subtilis str. 168 amino acid permease YdaO NP_388313.1 486432 D 224308 CDS NP_388314.1 16077500 938242 488314..488763 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513759; Product type pe : enzyme; 8-oxo-dGTP diphosphatase 488763 mutT 938242 mutT Bacillus subtilis subsp. subtilis str. 168 8-oxo-dGTP diphosphatase NP_388314.1 488314 D 224308 CDS NP_388315.1 16077501 938239 488830..490554 1 NC_000964.3 catalyzes the formation of acetyl phosphate from pyruvate; thiamine pyrophosphate-containing protein YdaP 490554 ydaP 938239 ydaP Bacillus subtilis subsp. subtilis str. 168 thiamine pyrophosphate-containing protein YdaP NP_388315.1 488830 D 224308 CDS YP_003097680.1 255767135 8302999 complement(490777..491043) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 491043 ydzK 8302999 ydzK Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097680.1 490777 R 224308 CDS NP_388317.1 16077503 938241 complement(491147..492424) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029030, 12950915, 14580210, 15849754, 16850406; Product type t : transporter; divalent metal cation transporter MntH 492424 mntH 938241 mntH Bacillus subtilis subsp. subtilis str. 168 divalent metal cation transporter MntH NP_388317.1 491147 R 224308 CDS NP_388318.1 16077504 938230 complement(492654..492911) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 492911 ydaS 938230 ydaS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388318.1 492654 R 224308 CDS NP_388319.1 16077505 939950 complement(492989..493441) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 493441 ydaT 939950 ydaT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388319.1 492989 R 224308 CDS NP_388320.1 16077506 938238 493559..494377 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 494377 ydbA 938238 ydbA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388320.1 493559 D 224308 CDS NP_388321.1 16077507 938235 494506..494877 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651322, 9669336; Product type f: factor; glucose starvation-inducible protein B 494877 gsiB 938235 gsiB Bacillus subtilis subsp. subtilis str. 168 glucose starvation-inducible protein B NP_388321.1 494506 D 224308 CDS NP_388322.1 16077508 935969 495009..495350 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme; hypothetical protein 495350 ydbB 935969 ydbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388322.1 495009 D 224308 CDS NP_388323.1 16077509 938234 495344..495703 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 495703 ydbC 938234 ydbC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388323.1 495344 D 224308 CDS NP_388324.1 16077510 938232 complement(495740..496561) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15231799; Product type pe : enzyme; manganese catalase 496561 ydbD 938232 ydbD Bacillus subtilis subsp. subtilis str. 168 manganese catalase NP_388324.1 495740 R 224308 CDS NP_388325.1 16077511 938226 complement(496646..497698) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10708364, 11566984, 1809844; Product type f : factor; C4-dicarboxylate-binding protein DctB 497698 dctB 938226 dctB Bacillus subtilis subsp. subtilis str. 168 C4-dicarboxylate-binding protein DctB NP_388325.1 496646 R 224308 CDS NP_388326.1 16077512 938231 497768..499375 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type rc: receptor; C4-dicarboxylate sensor kinase 499375 dctS 938231 dctS Bacillus subtilis subsp. subtilis str. 168 C4-dicarboxylate sensor kinase NP_388326.1 497768 D 224308 CDS NP_388327.1 16077513 940148 499365..500045 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627041, 11717295, 1290636, 12949159; Product type r: regulator; C4-dicarboxylate response regulator DctR 500045 dctR 940148 dctR Bacillus subtilis subsp. subtilis str. 168 C4-dicarboxylate response regulator DctR NP_388327.1 499365 D 224308 CDS NP_388328.1 16077514 938223 500166..501431 1 NC_000964.3 involved in the transport of C4-dicarboxylates across the membrane; C4-dicarboxylate transport protein 501431 dctP 938223 dctP Bacillus subtilis subsp. subtilis str. 168 C4-dicarboxylate transport protein NP_388328.1 500166 D 224308 CDS NP_388329.1 16077515 939948 501579..502631 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 502631 ydbI 939948 ydbI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388329.1 501579 D 224308 CDS NP_388330.1 16077516 938228 502908..503834 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 503834 ydbJ 938228 ydbJ Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388330.1 502908 D 224308 CDS NP_388331.1 16077517 939944 503854..504594 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 15849754, 16850406; Product type pt: transporter; membrane protein 504594 ydbK 939944 ydbK Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388331.1 503854 D 224308 CDS NP_388332.1 16077518 938227 504689..505024 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 505024 ydbL 938227 ydbL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388332.1 504689 D 224308 CDS NP_388333.1 16077519 939949 505152..506297 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748; Product type pe: enzyme; acyl-CoA dehydrogenase YdbM 506297 ydbM 939949 ydbM Bacillus subtilis subsp. subtilis str. 168 acyl-CoA dehydrogenase YdbM NP_388333.1 505152 D 224308 CDS NP_388334.1 16077520 938190 complement(506322..506501) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229, 16428414; hypothetical protein 506501 ydbN 938190 ydbN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388334.1 506322 R 224308 CDS NP_388335.1 16077521 938225 506866..507738 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter 507738 ydbO 938225 ydbO Bacillus subtilis subsp. subtilis str. 168 transporter NP_388335.1 506866 D 224308 CDS NP_388336.1 16077522 939940 complement(507753..508073) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; thioredoxin 508073 ydbP 939940 ydbP Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_388336.1 507753 R 224308 CDS NP_388337.1 16077523 938224 508248..509312 1 NC_000964.3 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 509312 ddl 938224 ddl Bacillus subtilis subsp. subtilis str. 168 D-alanine--D-alanine ligase NP_388337.1 508248 D 224308 CDS NP_388338.1 16077524 939947 509384..510757 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299; Product type e: enzyme; UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase 510757 murF 939947 murF Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase NP_388338.1 509384 D 224308 CDS NP_388339.1 16077525 938170 511106..512641 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840; Product type e: enzyme; ATP-dependent RNA helicase 512641 cshA 938170 cshA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent RNA helicase NP_388339.1 511106 D 224308 CDS NP_388340.1 16077526 940149 512814..513293 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 513293 ydbS 940149 ydbS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388340.1 512814 D 224308 CDS NP_388341.1 16077527 938221 513283..514764 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 514764 ydbT 938221 ydbT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388341.1 513283 D 224308 CDS NP_388342.1 16077528 939936 complement(515016..515615) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15616571, 15849754, 16850406; rhomboid protease YdcA 515615 ydcA 939936 ydcA Bacillus subtilis subsp. subtilis str. 168 rhomboid protease YdcA NP_388342.1 515016 R 224308 CDS NP_388343.1 16077529 938194 515710..516075 1 NC_000964.3 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; holo-[acyl-carrier-protein] synthase 516075 acpS 938194 acpS Bacillus subtilis subsp. subtilis str. 168 holo-[acyl-carrier-protein] synthase NP_388343.1 515710 D 224308 CDS NP_388344.2 255767136 938166 516241..517257 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type lp : lipoprotein; sporulation protein YdcC 517257 ydcC 938166 ydcC Bacillus subtilis subsp. subtilis str. 168 sporulation protein YdcC NP_388344.2 516241 D 224308 CDS NP_388345.1 16077531 939942 517372..518541 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15043879, 18399999, 2835089; Product type e: enzyme; alanine racemase 1 518541 alrA 939942 alrA Bacillus subtilis subsp. subtilis str. 168 alanine racemase 1 NP_388345.1 517372 D 224308 CDS NP_388346.1 16077532 938177 518657..518938 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type r: regulator; antitoxin EndoAI 518938 endB 938177 endB Bacillus subtilis subsp. subtilis str. 168 antitoxin EndoAI NP_388346.1 518657 D 224308 CDS NP_388347.1 16077533 939935 518943..519293 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15882409; Product type e: enzyme; mRNA interferase EndoA 519293 ndoA 939935 ndoA Bacillus subtilis subsp. subtilis str. 168 mRNA interferase EndoA NP_388347.1 518943 D 224308 CDS NP_388348.1 16077534 938176 519408..520232 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT co-antagonist protein RsbRA 520232 rsbRA 938176 rsbRA Bacillus subtilis subsp. subtilis str. 168 RsbT co-antagonist protein RsbRA NP_388348.1 519408 D 224308 CDS NP_388349.1 16077535 938157 520237..520602 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT antagonist protein RsbS 520602 rsbS 938157 rsbS Bacillus subtilis subsp. subtilis str. 168 RsbT antagonist protein RsbS NP_388349.1 520237 D 224308 CDS NP_388350.1 16077536 938168 520606..521007 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665, 11157946; Product type e: enzyme; serine/threonine protein kinase 521007 rsbT 938168 rsbT Bacillus subtilis subsp. subtilis str. 168 serine/threonine protein kinase NP_388350.1 520606 D 224308 CDS NP_388351.1 16077537 939939 521019..522026 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15583165, 16963570, 17158665; Product type e: enzyme; phosphoserine phosphatase RsbU 522026 rsbU 939939 rsbU Bacillus subtilis subsp. subtilis str. 168 phosphoserine phosphatase RsbU NP_388351.1 521019 D 224308 CDS NP_388352.1 16077538 939930 522088..522417 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15342585, 15583165, 16077134, 16885458; Product type f: factor; anti-sigma-B factor antagonist 522417 rsbV 939930 rsbV Bacillus subtilis subsp. subtilis str. 168 anti-sigma-B factor antagonist NP_388352.1 522088 D 224308 CDS NP_388353.1 16077539 938167 522414..522896 1 NC_000964.3 binds to sigma-B preventing the formation of an RNA polymerase holoenzyme; serine-protein kinase RsbW 522896 rsbW 938167 rsbW Bacillus subtilis subsp. subtilis str. 168 serine-protein kinase RsbW NP_388353.1 522414 D 224308 CDS NP_388354.2 255767137 939937 522862..523650 1 NC_000964.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma B is not essential for sporulation; rather it is required for maximal expression of ctc and csbA which are transcribed in the early stationary phase under conditions inimical to sporulation; induced by heat shock, salt stress, oxidative stress, glucose limitation, oxygen limitation and entry into stationary phase; RNA polymerase sigma-B factor 523650 sigB 939937 sigB Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-B factor NP_388354.2 522862 D 224308 CDS NP_388355.1 16077541 938155 523650..524249 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10671474, 12950928, 15466036, 9068644, 9658013; Product type e: enzyme; phosphoserine phosphatase RsbX 524249 rsbX 938155 rsbX Bacillus subtilis subsp. subtilis str. 168 phosphoserine phosphatase RsbX NP_388355.1 523650 D 224308 CDS NP_388356.1 16077542 938158 524492..524785 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 524785 ydcF 938158 ydcF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388356.1 524492 D 224308 CDS NP_388357.1 16077543 938162 524782..525222 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 525222 ydcG 938162 ydcG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388357.1 524782 D 224308 CDS NP_388358.1 16077544 939928 525206..525649 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12088660; Product type pr : regulator; MarR family transcriptional regulator 525649 ydcH 939928 ydcH Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388358.1 525206 D 224308 CDS NP_388359.2 50812188 939932 525743..527902 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 527902 ydcI 939932 ydcI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388359.2 525743 D 224308 CDS NP_388360.1 16077546 938154 528129..528581 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; protein SprT-like 528581 ydcK 938154 ydcK Bacillus subtilis subsp. subtilis str. 168 protein SprT-like NP_388360.1 528129 D 224308 CDS NP_388361.1 16077547 938151 complement(529505..530611) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; ICEBs1 integrase 530611 ydcL 938151 ydcL Bacillus subtilis subsp. subtilis str. 168 ICEBs1 integrase NP_388361.1 529505 R 224308 CDS NP_388362.1 16077548 939924 complement(530624..531133) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18761623; Product type cp: cell process; metallopeptidase ImmA 531133 immA 939924 immA Bacillus subtilis subsp. subtilis str. 168 metallopeptidase ImmA NP_388362.1 530624 R 224308 CDS NP_388363.1 16077549 938150 complement(531130..531513) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin; XRE family transcriptional regulator 531513 immR 938150 immR Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_388363.1 531130 R 224308 CDS NP_388364.1 16077550 939938 531787..531981 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3269394; Product type h : extrachromosomal origin; excisionase 531981 sacV 939938 sacV Bacillus subtilis subsp. subtilis str. 168 excisionase NP_388364.1 531787 D 224308 CDS YP_003097681.1 255767138 8303154 531978..532238 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 532238 ydzL 8303154 ydzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097681.1 531978 D 224308 CDS NP_388365.1 16077551 938142 532292..532552 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 532552 ydcO 938142 ydcO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388365.1 532292 D 224308 CDS NP_388366.1 16077552 939920 532922..533302 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 533302 ydcP 939920 ydcP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388366.1 532922 D 224308 CDS NP_388367.1 16077553 939923 533338..534780 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; Ftsk domain-containing protein YdcQ 534780 ydcQ 939923 ydcQ Bacillus subtilis subsp. subtilis str. 168 Ftsk domain-containing protein YdcQ NP_388367.1 533338 D 224308 CDS NP_388368.1 16077554 939922 534773..535831 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA relaxase NicK 535831 ydcR 939922 ydcR Bacillus subtilis subsp. subtilis str. 168 DNA relaxase NicK NP_388368.1 534773 D 224308 CDS NP_388369.1 16077555 938148 536096..536365 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536365 ydcS 938148 ydcS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388369.1 536096 D 224308 CDS NP_388370.1 16077556 938146 536404..536670 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536670 ydcT 938146 ydcT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388370.1 536404 D 224308 CDS NP_388371.1 16077557 938135 536687..536995 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 536995 yddA 938135 yddA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388371.1 536687 D 224308 CDS NP_388372.1 16077558 939918 536985..538049 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 538049 yddB 939918 yddB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388372.1 536985 D 224308 CDS NP_388373.1 16077559 938144 538061..538309 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 538309 yddC 938144 yddC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388373.1 538061 D 224308 CDS NP_388374.1 16077560 939921 538322..538846 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 538846 yddD 939921 yddD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388374.1 538322 D 224308 CDS NP_388375.2 255767139 938130 538836..541229 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 541229 yddE 938130 yddE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388375.2 538836 D 224308 CDS NP_388376.1 16077562 938143 541248..541574 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 541574 yddF 938143 yddF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388376.1 541248 D 224308 CDS NP_388377.1 16077563 938141 541578..544025 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 544025 yddG 938141 yddG Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388377.1 541578 D 224308 CDS NP_388378.1 16077564 938136 544022..545011 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; endopeptidase YddH 545011 yddH 938136 yddH Bacillus subtilis subsp. subtilis str. 168 endopeptidase YddH NP_388378.1 544022 D 224308 CDS NP_388379.1 16077565 939919 545026..545532 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 545532 yddI 939919 yddI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388379.1 545026 D 224308 CDS NP_388380.1 16077566 939925 545595..545975 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 545975 yddJ 939925 yddJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388380.1 545595 D 224308 CDS NP_388381.1 16077567 939917 complement(546166..546966) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 546966 yddK 939917 yddK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388381.1 546166 R 224308 CDS NP_388382.1 16077568 938127 547306..548481 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16105942; Product type r: regulator; response regulator aspartate phosphatase I 548481 rapI 938127 rapI Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase I NP_388382.1 547306 D 224308 CDS NP_388383.1 16077569 939927 548438..548557 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type r: regulator; secreted regulator of the activity of phosphatase RapI 548557 phrI 939927 phrI Bacillus subtilis subsp. subtilis str. 168 secreted regulator of the activity of phosphatase RapI NP_388383.1 548438 D 224308 CDS NP_388384.1 16077570 938134 548710..549651 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; helicase 549651 yddM 938134 yddM Bacillus subtilis subsp. subtilis str. 168 helicase NP_388384.1 548710 D 224308 CDS NP_388385.1 16077571 938133 complement(550240..551259) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme; hypothetical protein 551259 yddN 938133 yddN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388385.1 550240 R 224308 CDS NP_388386.1 16077572 938119 551519..551929 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator; AsnC family transcriptional regulator 551929 lrpA 938119 lrpA Bacillus subtilis subsp. subtilis str. 168 AsnC family transcriptional regulator NP_388386.1 551519 D 224308 CDS NP_388387.1 16077573 939912 complement(552052..552501) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902725, 12675791, 17223133; Product type r: regulator; AsnC family transcriptional regulator 552501 lrpB 939912 lrpB Bacillus subtilis subsp. subtilis str. 168 AsnC family transcriptional regulator NP_388387.1 552052 R 224308 CDS NP_388388.1 16077574 938129 552616..553158 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase 553158 yddQ 938129 yddQ Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_388388.1 552616 D 224308 CDS NP_388389.1 16077575 939915 553711..554475 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 554475 yddR 939915 yddR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388389.1 553711 D 224308 CDS NP_388390.1 16077576 938128 554669..555979 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 555979 yddS 938128 yddS Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388390.1 554669 D 224308 CDS YP_003097682.1 255767140 8303141 556562..556738 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 556738 ydzM 8303141 ydzM Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097682.1 556562 D 224308 CDS NP_388391.1 16077577 939913 556763..557449 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 557449 yddT 939913 yddT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388391.1 556763 D 224308 CDS YP_003097683.1 255767141 8303142 557873..558058 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 558058 ydzN 8303142 ydzN Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097683.1 557873 D 224308 CDS NP_388392.1 16077578 939914 558408..559001 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YdeA 559001 ydeA 939914 ydeA Bacillus subtilis subsp. subtilis str. 168 protease YdeA NP_388392.1 558408 D 224308 CDS NP_388393.1 16077579 938114 559264..559464 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10517332, 12427936, 9914312, 9920884; Product type f: factor; cold shock protein CspC 559464 cspC 938114 cspC Bacillus subtilis subsp. subtilis str. 168 cold shock protein CspC NP_388393.1 559264 D 224308 CDS NP_388394.1 16077580 938120 complement(560151..560612) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcription factor YdeB 560612 ydeB 938120 ydeB Bacillus subtilis subsp. subtilis str. 168 transcription factor YdeB NP_388394.1 560151 R 224308 CDS NP_388395.1 16077581 938121 complement(561180..561416) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; permease 561416 ydzE 938121 ydzE Bacillus subtilis subsp. subtilis str. 168 permease NP_388395.1 561180 R 224308 CDS NP_388396.1 16077582 938103 complement(561514..562389) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 562389 ydeC 938103 ydeC Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388396.1 561514 R 224308 CDS NP_388397.1 16077583 939906 562502..563461 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 563461 ydeD 939906 ydeD Bacillus subtilis subsp. subtilis str. 168 transporter NP_388397.1 562502 D 224308 CDS NP_388398.1 16077584 938117 complement(563614..564486) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 564486 ydeE 938117 ydeE Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388398.1 563614 R 224308 CDS NP_388399.1 16077585 939911 564704..566101 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 566101 ydeF 939911 ydeF Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388399.1 564704 D 224308 CDS NP_388400.1 16077586 938115 566211..567503 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 567503 ydeG 938115 ydeG Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388400.1 566211 D 224308 CDS NP_388401.1 16077587 938097 567662..568108 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 568108 ydeH 938097 ydeH Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388401.1 567662 D 224308 CDS NP_388402.1 16077588 939916 568345..568938 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 568938 ydeI 939916 ydeI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388402.1 568345 D 224308 CDS NP_388403.1 16077589 939910 complement(569290..569949) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 569949 ydeJ 939910 ydeJ Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388403.1 569290 R 224308 CDS NP_388404.1 16077590 938112 complement(570371..571234) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 571234 ydeK 938112 ydeK Bacillus subtilis subsp. subtilis str. 168 transporter NP_388404.1 570371 R 224308 CDS NP_388405.1 16077591 939904 571389..572780 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 572780 ydeL 939904 ydeL Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388405.1 571389 D 224308 CDS NP_388406.1 16077592 938104 572974..573399 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1556068; Product type pe : enzyme; hypothetical protein 573399 ydeM 938104 ydeM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388406.1 572974 D 224308 CDS NP_388407.1 16077593 939908 complement(573452..574024) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15159570; Product type e: enzyme; hydrolase 574024 ydeN 939908 ydeN Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_388407.1 573452 R 224308 CDS NP_388408.1 16077594 938088 complement(574106..574435) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator 574435 ydzF 938088 ydzF Bacillus subtilis subsp. subtilis str. 168 HxlR family transcriptional regulator NP_388408.1 574106 R 224308 CDS NP_388409.1 16077595 938098 574690..575562 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 575562 ydeO 938098 ydeO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388409.1 574690 D 224308 CDS NP_388410.1 16077596 938100 complement(575712..576098) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator 576098 ydeP 938100 ydeP Bacillus subtilis subsp. subtilis str. 168 HxlR family transcriptional regulator NP_388410.1 575712 R 224308 CDS NP_388411.1 16077597 939902 576209..576802 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H oxidoreductase 576802 ydeQ 939902 ydeQ Bacillus subtilis subsp. subtilis str. 168 NAD(P)H oxidoreductase NP_388411.1 576209 D 224308 CDS NP_388412.1 16077598 938096 complement(576946..578133) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 578133 ydeR 938096 ydeR Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388412.1 576946 R 224308 CDS NP_388413.1 16077599 938083 578337..578933 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator; TetR family transcriptional regulator 578933 ydeS 938083 ydeS Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388413.1 578337 D 224308 CDS YP_003097684.1 255767142 8303150 579047..579232 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 579232 ydzO 8303150 ydzO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097684.1 579047 D 224308 CDS NP_388414.1 16077600 938089 579541..579876 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator; ArsR family transcriptional regulator 579876 aseR 938089 aseR Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_388414.1 579541 D 224308 CDS NP_388415.1 16077601 939905 579889..581196 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; arsenic pump protein 581196 ydfA 939905 ydfA Bacillus subtilis subsp. subtilis str. 168 arsenic pump protein NP_388415.1 579889 D 224308 CDS NP_388416.1 16077602 938079 581694..582479 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; N-acetyltransferase YdfB 582479 ydfB 938079 ydfB Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YdfB NP_388416.1 581694 D 224308 CDS NP_388417.1 16077603 938086 complement(582536..583456) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 583456 ydfC 938086 ydfC Bacillus subtilis subsp. subtilis str. 168 transporter NP_388417.1 582536 R 224308 CDS NP_388418.1 16077604 939903 583589..585037 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 585037 ydfD 939903 ydfD Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388418.1 583589 D 224308 CDS NP_388419.1 16077605 939898 complement(585155..585778) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 585778 ydfE 939898 ydfE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388419.1 585155 R 224308 CDS NP_388420.1 16077606 938084 585868..586548 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; ArsR family transcriptional regulator 586548 ydfF 938084 ydfF Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_388420.1 585868 D 224308 CDS NP_388421.1 16077607 938081 complement(586628..587071) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 587071 ydfG 938081 ydfG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388421.1 586628 R 224308 CDS YP_003097685.1 255767143 8302941 complement(587157..587336) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 587336 ydzP 8302941 ydzP Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097685.1 587157 R 224308 CDS YP_003097686.1 255767144 8303032 complement(587333..587476) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 587476 ydzQ 8303032 ydzQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097686.1 587333 R 224308 CDS NP_388422.1 16077608 938076 587744..588967 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type rc: receptor; sensor histidine kinase 588967 ydfH 938076 ydfH Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388422.1 587744 D 224308 CDS NP_388423.1 16077609 938080 588960..589601 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15941986; Product type r: regulator; transcriptional regulator 589601 ydfI 938080 ydfI Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388423.1 588960 D 224308 CDS NP_388424.1 16077610 939901 589717..591891 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pt : transporter; membrane protein 591891 ydfJ 939901 ydfJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388424.1 589717 D 224308 CDS NP_388425.1 16077611 938069 complement(592303..593205) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7765103; Product type e : enzyme; carboxylesterase nap 593205 nap 938069 nap Bacillus subtilis subsp. subtilis str. 168 carboxylesterase nap NP_388425.1 592303 R 224308 CDS NP_388426.1 16077612 939896 complement(593407..594096) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10200972, 15849754, 16850406; Product type pm: membrane component; membrane protein 594096 ydfK 939896 ydfK Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388426.1 593407 R 224308 CDS NP_388427.1 16077613 938078 complement(594186..594998) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 594998 ydfL 938078 ydfL Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388427.1 594186 R 224308 CDS NP_388428.2 255767145 939900 complement(595109..596002) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter 596002 ydfM 939900 ydfM Bacillus subtilis subsp. subtilis str. 168 transporter NP_388428.2 595109 R 224308 CDS NP_388429.1 16077615 939899 596478..597098 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; NAD(P)H nitroreductase MhqN 597098 ydfN 939899 ydfN Bacillus subtilis subsp. subtilis str. 168 NAD(P)H nitroreductase MhqN NP_388429.1 596478 D 224308 CDS NP_388430.1 16077616 939894 597114..598052 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqO 598052 ydfO 939894 ydfO Bacillus subtilis subsp. subtilis str. 168 ring-cleaving dioxygenase MhqO NP_388430.1 597114 D 224308 CDS NP_388431.1 16077617 938077 598154..598543 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15306018, 15849754, 16850406, 17407181; Product type pe: enzyme; oxidoreductase 598543 ydfP 938077 ydfP Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388431.1 598154 D 224308 CDS NP_388432.1 16077618 938062 598729..599067 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; thioredoxin 599067 ydfQ 938062 ydfQ Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_388432.1 598729 D 224308 CDS NP_388433.1 16077619 938074 complement(599107..599343) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 599343 ydzH 938074 ydzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388433.1 599107 R 224308 CDS YP_003097687.1 255767146 8303211 complement(599875..600105) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; spore germination protein 600105 ydzR 8303211 ydzR Bacillus subtilis subsp. subtilis str. 168 spore germination protein YP_003097687.1 599875 R 224308 CDS NP_388434.1 16077620 939897 complement(600229..600906) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 600906 ydfR 939897 ydfR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388434.1 600229 R 224308 CDS NP_388435.1 16077621 939890 601019..601726 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 601726 ydfS 939890 ydfS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388435.1 601019 D 224308 CDS NP_388436.1 16077622 938073 complement(601741..602172) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673; Product type f: factor; spore coat protein P 602172 cotP 938073 cotP Bacillus subtilis subsp. subtilis str. 168 spore coat protein P NP_388436.1 601741 R 224308 CDS NP_388437.1 16077623 938065 complement(602185..602427) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 602427 ydgA 938065 ydgA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388437.1 602185 R 224308 CDS NP_388438.1 16077624 938056 complement(602441..602713) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 602713 ydgB 938056 ydgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388438.1 602441 R 224308 CDS NP_388439.1 16077625 938064 603012..603599 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 603599 ydgC 938064 ydgC Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388439.1 603012 D 224308 CDS NP_388440.1 16077626 939895 603596..603940 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 603940 ydgD 939895 ydgD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388440.1 603596 D 224308 CDS NP_388441.1 16077627 939907 604103..604576 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YdgE 604576 ydgE 939907 ydgE Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YdgE NP_388441.1 604103 D 224308 CDS NP_388442.1 16077628 938053 complement(604736..606379) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16109936; Product type t: transporter; nucleotide-binding protein ExpZ 606379 vmlR 938053 vmlR Bacillus subtilis subsp. subtilis str. 168 nucleotide-binding protein ExpZ NP_388442.1 604736 R 224308 CDS NP_388443.1 16077629 938050 complement(606699..608075) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16109936, 16850406; Product type pt: transporter; transporter 608075 ydgF 938050 ydgF Bacillus subtilis subsp. subtilis str. 168 transporter NP_388443.1 606699 R 224308 CDS NP_388444.1 16077630 938057 complement(608246..608764) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12644484, 16267290; Product type r : regulator; protein DinB 608764 dinB 938057 dinB Bacillus subtilis subsp. subtilis str. 168 protein DinB NP_388444.1 608246 R 224308 CDS NP_388445.1 16077631 939880 608933..609391 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 609391 ydgG 939880 ydgG Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388445.1 608933 D 224308 CDS NP_388446.1 16077632 938043 609388..612045 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941986; Product type pm : membrane component; membrane protein 612045 ydgH 938043 ydgH Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388446.1 609388 D 224308 CDS NP_388447.1 16077633 938001 complement(612191..612820) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H nitroreductase YdgI 612820 ydgI 938001 ydgI Bacillus subtilis subsp. subtilis str. 168 NAD(P)H nitroreductase YdgI NP_388447.1 612191 R 224308 CDS NP_388448.1 16077634 938036 complement(612836..613330) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 613330 ydgJ 938036 ydgJ Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388448.1 612836 R 224308 CDS NP_388449.1 16077635 938060 613641..614849 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 614849 ydgK 938060 ydgK Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388449.1 613641 D 224308 CDS NP_388450.2 255767147 939893 complement(614885..615622) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 615622 ydhB 939893 ydhB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388450.2 614885 R 224308 CDS NP_388451.1 16077637 938042 615871..616545 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 616545 ydhC 938042 ydhC Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388451.1 615871 D 224308 CDS NP_388452.2 255767148 939885 616672..617934 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11011148, 12177332; Product type cp: cell process; sporulation protein 617934 ydhD 939885 ydhD Bacillus subtilis subsp. subtilis str. 168 sporulation protein NP_388452.2 616672 D 224308 CDS NP_388453.2 255767149 939868 618095..619282 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YdhE 619282 ydhE 939868 ydhE Bacillus subtilis subsp. subtilis str. 168 UDP-glucosyltransferase YdhE NP_388453.2 618095 D 224308 CDS NP_388454.1 16077640 938019 complement(619321..620031) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557812; Product type lp : lipoprotein; hypothetical protein 620031 ydhF 938019 ydhF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388454.1 619321 R 224308 CDS NP_388455.2 255767150 938004 complement(620097..621485) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 16030210, 16491025, 9335276; Product type e: enzyme; alkaline phosphatase 3 621485 phoB 938004 phoB Bacillus subtilis subsp. subtilis str. 168 alkaline phosphatase 3 NP_388455.2 620097 R 224308 CDS NP_388456.1 16077642 938031 621847..622218 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 622218 ydhG 938031 ydhG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388456.1 621847 D 224308 CDS NP_388457.1 16077643 939877 complement(622293..622790) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 622790 ydhH 939877 ydhH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388457.1 622293 R 224308 CDS NP_388458.1 16077644 939866 complement(622808..623290) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 623290 ydhI 939866 ydhI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388458.1 622808 R 224308 CDS NP_388459.1 16077645 938014 623373..624350 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 624350 ydhJ 938014 ydhJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388459.1 623373 D 224308 CDS NP_388460.1 16077646 939873 624492..625109 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 625109 ydhK 939873 ydhK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388460.1 624492 D 224308 CDS NP_388461.2 50812189 937996 complement(625125..626291) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12923093, 15849754, 16850406, 17935948; Product type t: transporter; purine efflux pump PbuE 626291 pbuE 937996 pbuE Bacillus subtilis subsp. subtilis str. 168 purine efflux pump PbuE NP_388461.2 625125 R 224308 CDS NP_388462.1 16077648 938018 626622..626933 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 18177310; Product type t: transporter; PTS system oligo-beta-mannoside transporter subunit IIB 626933 gmuB 938018 gmuB Bacillus subtilis subsp. subtilis str. 168 PTS system oligo-beta-mannoside transporter subunit IIB NP_388462.1 626622 D 224308 CDS NP_388463.2 255767151 938039 626933..627265 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; PTS system oligo-beta-mannoside transporter subunit IIA 627265 gmuA 938039 gmuA Bacillus subtilis subsp. subtilis str. 168 PTS system oligo-beta-mannoside transporter subunit IIA NP_388463.2 626933 D 224308 CDS NP_388464.1 16077650 939882 627284..628612 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 18177310; Product type t : transporter; PTS system oligo-beta-mannoside transporter subunit IIC 628612 gmuC 939882 gmuC Bacillus subtilis subsp. subtilis str. 168 PTS system oligo-beta-mannoside transporter subunit IIC NP_388464.1 627284 D 224308 CDS NP_388465.1 16077651 939872 628630..630027 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714, 18177310; Product type e: enzyme; 6-phospho-beta-glucosidase GmuD 630027 gmuD 939872 gmuD Bacillus subtilis subsp. subtilis str. 168 6-phospho-beta-glucosidase GmuD NP_388465.1 628630 D 224308 CDS NP_388466.1 16077652 939879 630170..630883 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310; Product type r: regulator; GntR family transcriptional regulator 630883 gmuR 939879 gmuR Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388466.1 630170 D 224308 CDS NP_388467.1 16077653 938016 630912..631811 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15018644, 18177310; Product type pe: enzyme; fructokinase 631811 gmuE 938016 gmuE Bacillus subtilis subsp. subtilis str. 168 fructokinase NP_388467.1 630912 D 224308 CDS NP_388468.1 16077654 938028 631808..632755 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 10704478, 18177310, 3017192; Product type e: enzyme; mannose-6-phosphate isomerase GmuF 632755 gmuF 938028 gmuF Bacillus subtilis subsp. subtilis str. 168 mannose-6-phosphate isomerase GmuF NP_388468.1 631808 D 224308 CDS NP_388469.2 255767152 938034 632774..633862 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18177310, 2694961, 7727534; Product type e: enzyme; mannan endo-1,4-beta-mannosidase 633862 gmuG 938034 gmuG Bacillus subtilis subsp. subtilis str. 168 mannan endo-1,4-beta-mannosidase NP_388469.2 632774 D 224308 CDS NP_388471.1 16077657 939867 640662..641639 1 NC_000964.3 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP; thiamine-monophosphate kinase 641639 thiL 939867 thiL Bacillus subtilis subsp. subtilis str. 168 thiamine-monophosphate kinase NP_388471.1 640662 D 224308 CDS NP_388472.1 16077658 938047 641654..642130 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pe: enzyme; UPF0079 ATP-binding protein YdiB 642130 ydiB 938047 ydiB Bacillus subtilis subsp. subtilis str. 168 UPF0079 ATP-binding protein YdiB NP_388472.1 641654 D 224308 CDS NP_388473.1 16077659 939874 642111..642800 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 17005971; Product type pf: factor; hypothetical protein 642800 ydiC 939874 ydiC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388473.1 642111 D 224308 CDS NP_388474.1 16077660 937997 642810..643265 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2828880; Product type e: enzyme; ribosomal-protein-alanine acetyltransferase 643265 rimI 937997 rimI Bacillus subtilis subsp. subtilis str. 168 ribosomal-protein-alanine acetyltransferase NP_388474.1 642810 D 224308 CDS NP_388475.1 16077661 938020 643258..644298 1 NC_000964.3 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; tRNA threonylcarbamoyladenosine biosynthesis protein Gcp 644298 gcp 938020 gcp Bacillus subtilis subsp. subtilis str. 168 tRNA threonylcarbamoyladenosine biosynthesis protein Gcp NP_388475.1 643258 D 224308 CDS NP_388476.2 255767153 938013 complement(644528..646456) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11916677; Product type pt : transporter; ABC transporter ATP-binding protein 646456 ydiF 938013 ydiF Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388476.2 644528 R 224308 CDS NP_388477.1 16077663 939875 646582..647094 1 NC_000964.3 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis; cyclic pyranopterin monophosphate synthase accessory protein 647094 moaC 939875 moaC Bacillus subtilis subsp. subtilis str. 168 cyclic pyranopterin monophosphate synthase accessory protein NP_388477.1 646582 D 224308 CDS NP_388478.1 16077664 939871 647091..647738 1 NC_000964.3 modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor rex 647738 ydiH 939871 ydiH Bacillus subtilis subsp. subtilis str. 168 redox-sensing transcriptional repressor rex NP_388478.1 647091 D 224308 CDS NP_388479.1 16077665 939878 647760..647933 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 19049517; Product type t: transporter; Sec-independent protein translocase protein TatAy 647933 tatAY 939878 tatAY Bacillus subtilis subsp. subtilis str. 168 Sec-independent protein translocase protein TatAy NP_388479.1 647760 D 224308 CDS NP_388480.1 16077666 938010 647940..648704 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775, 15187182, 15849754, 16850406, 19049517; Product type t : transporter; Sec-independent protein translocase protein TatCy 648704 tatCY 938010 tatCY Bacillus subtilis subsp. subtilis str. 168 Sec-independent protein translocase protein TatCy NP_388480.1 647940 D 224308 CDS NP_388481.1 16077667 939870 complement(648742..648933) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; lipoprotein 648933 ydiK 939870 ydiK Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388481.1 648742 R 224308 CDS NP_388482.1 16077668 938033 complement(648930..649664) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane peptidase YdiL 649664 ydiL 938033 ydiL Bacillus subtilis subsp. subtilis str. 168 membrane peptidase YdiL NP_388482.1 648930 R 224308 CDS NP_388483.2 50812190 938006 649903..650187 1 NC_000964.3 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; 10 kDa chaperonin 650187 groES 938006 groES Bacillus subtilis subsp. subtilis str. 168 10 kDa chaperonin NP_388483.2 649903 D 224308 CDS NP_388484.1 16077670 938045 650234..651868 1 NC_000964.3 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; 60 kDa chaperonin 651868 groEL 938045 groEL Bacillus subtilis subsp. subtilis str. 168 60 kDa chaperonin NP_388484.1 650234 D 224308 CDS NP_388485.1 16077671 939886 653432..653812 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 653812 ydiM 939886 ydiM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388485.1 653432 D 224308 CDS YP_003097688.1 255767154 8302904 654071..654343 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 654343 ydzU 8302904 ydzU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097688.1 654071 D 224308 CDS NP_388487.1 16077673 939892 655223..656506 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 12682299, 16014871, 16267290; Product type e: enzyme; BsuMI modification methylase subunit YdiO 656506 ydiO 939892 ydiO Bacillus subtilis subsp. subtilis str. 168 BsuMI modification methylase subunit YdiO NP_388487.1 655223 D 224308 CDS NP_388488.1 16077674 939876 656528..657697 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 16267290; Product type e: enzyme; BsuMI modification methylase subunit YdiP 657697 ydiP 939876 ydiP Bacillus subtilis subsp. subtilis str. 168 BsuMI modification methylase subunit YdiP NP_388488.1 656528 D 224308 CDS NP_388490.1 16077676 938002 659623..660564 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814, 15728999; Product type h: extrachromosomal origin; type-2 restriction enzyme BsuMI component YdiR 660564 ydiR 938002 ydiR Bacillus subtilis subsp. subtilis str. 168 type-2 restriction enzyme BsuMI component YdiR NP_388490.1 659623 D 224308 CDS NP_388491.1 16077677 938023 660596..661627 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme; type-2 restriction enzyme BsuMI component YdiS 661627 ydiS 938023 ydiS Bacillus subtilis subsp. subtilis str. 168 type-2 restriction enzyme BsuMI component YdiS NP_388491.1 660596 D 224308 CDS NP_388492.1 16077678 939884 661630..663027 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751814; Product type e: enzyme; type-2 restriction enzyme BsuMI component YdjA 663027 ydjA 939884 ydjA Bacillus subtilis subsp. subtilis str. 168 type-2 restriction enzyme BsuMI component YdjA NP_388492.1 661630 D 224308 CDS NP_388493.1 16077679 935917 663601..663936 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 663936 ydjB 935917 ydjB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388493.1 663601 D 224308 CDS NP_388494.1 16077680 936012 664319..664669 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 664669 ydjC 936012 ydjC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388494.1 664319 D 224308 CDS NP_388495.1 16077681 938026 complement(664775..667264) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11118449, 11390381, 12897001; Product type r: regulator; transcription activator GutR 667264 gutR 938026 gutR Bacillus subtilis subsp. subtilis str. 168 transcription activator GutR NP_388495.1 664775 R 224308 CDS NP_388496.1 16077682 939495 667466..668527 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897001; Product type e: enzyme; sorbitol dehydrogenase 668527 gutB 939495 gutB Bacillus subtilis subsp. subtilis str. 168 sorbitol dehydrogenase NP_388496.1 667466 D 224308 CDS NP_388497.1 16077683 936004 668601..669992 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12897001; Product type t: transporter; glucitol transport protein GutA 669992 gutP 936004 gutP Bacillus subtilis subsp. subtilis str. 168 glucitol transport protein GutA NP_388497.1 668601 D 224308 CDS NP_388498.1 16077684 939494 670087..671049 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; sugar kinase YdjE 671049 ydjE 939494 ydjE Bacillus subtilis subsp. subtilis str. 168 sugar kinase YdjE NP_388498.1 670087 D 224308 CDS NP_388499.1 16077685 936013 671245..671928 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11454200; Product type h: extrachromosomal origin; phage shock protein A homolog 671928 pspA 936013 pspA Bacillus subtilis subsp. subtilis str. 168 phage shock protein A homolog NP_388499.1 671245 D 224308 CDS NP_388500.1 16077686 939489 671994..673019 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 673019 ydjG 939489 ydjG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388500.1 671994 D 224308 CDS NP_388501.1 16077687 936015 673019..673783 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 673783 ydjH 936015 ydjH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388501.1 673019 D 224308 CDS NP_388502.1 16077688 939493 673814..674785 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 674785 ydjI 939493 ydjI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388502.1 673814 D 224308 CDS NP_388503.1 16077689 936027 complement(674832..675857) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; membrane protein 675857 ydjJ 936027 ydjJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388503.1 674832 R 224308 CDS NP_388504.1 16077690 936014 676442..677863 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter; major myo-inositol transporter IolT 677863 iolT 936014 iolT Bacillus subtilis subsp. subtilis str. 168 major myo-inositol transporter IolT NP_388504.1 676442 D 224308 CDS NP_388505.1 16077691 939490 complement(677911..678951) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 18820069; Product type e: enzyme; (r,r)-butanediol dehydrogenase 678951 bdhA 939490 bdhA Bacillus subtilis subsp. subtilis str. 168 (r,r)-butanediol dehydrogenase NP_388505.1 677911 R 224308 CDS NP_388506.1 16077692 936017 679390..679761 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 679761 ydjM 936017 ydjM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388506.1 679390 D 224308 CDS NP_388507.1 16077693 939488 679827..680873 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 680873 ydjN 939488 ydjN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388507.1 679827 D 224308 CDS YP_003097689.1 255767155 8303125 complement(680907..681065) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 681065 ydzJ 8303125 ydzJ Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097689.1 680907 R 224308 CDS NP_388508.1 16077694 936021 complement(681255..681464) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 681464 ydjO 936021 ydjO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388508.1 681255 R 224308 CDS NP_388509.1 16077695 936035 complement(681547..682362) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pe : enzyme; AB hydrolase superfamily protein YdjP 682362 ydjP 936035 ydjP Bacillus subtilis subsp. subtilis str. 168 AB hydrolase superfamily protein YdjP NP_388509.1 681547 R 224308 CDS NP_388510.1 16077696 936018 complement(682375..683364) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 683364 yeaA 936018 yeaA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388510.1 682375 R 224308 CDS NP_388511.1 16077697 936023 complement(683462..685003) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11514528, 12637519, 16391148, 17242517, 18031270; Product type e: enzyme; spore coat protein A 685003 cotA 936023 cotA Bacillus subtilis subsp. subtilis str. 168 spore coat protein A NP_388511.1 683462 R 224308 CDS NP_388512.2 255767156 939485 complement(685155..686564) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16547045, 16850406, 8951816, 9677314; Product type t: transporter; GABA permease 686564 gabP 939485 gabP Bacillus subtilis subsp. subtilis str. 168 GABA permease NP_388512.2 685155 R 224308 CDS YP_003097690.1 255767157 8303160 complement(686602..686889) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 686889 ydzX 8303160 ydzX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097690.1 686602 R 224308 CDS NP_388513.1 16077699 936032 686962..687834 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; transporter 687834 yeaB 936032 yeaB Bacillus subtilis subsp. subtilis str. 168 transporter NP_388513.1 686962 D 224308 CDS NP_388514.2 255767158 939484 688184..689146 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 689146 yeaC 939484 yeaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388514.2 688184 D 224308 CDS NP_388515.2 255767159 939486 689146..690342 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 690342 yeaD 939486 yeaD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388515.2 689146 D 224308 CDS NP_388516.2 255767160 936029 690364..692577 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 692577 yebA 936029 yebA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388516.2 690364 D 224308 CDS NP_388517.2 255767161 936028 692740..694281 1 NC_000964.3 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 694281 guaA 936028 guaA Bacillus subtilis subsp. subtilis str. 168 GMP synthase NP_388517.2 692740 D 224308 CDS NP_388518.1 16077704 936043 694662..695984 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 12923093, 15849754, 16850406, 3110131; Product type t : transporter; guanine/hypoxanthine permease PbuG 695984 pbuG 936043 pbuG Bacillus subtilis subsp. subtilis str. 168 guanine/hypoxanthine permease PbuG NP_388518.1 694662 D 224308 CDS NP_388519.2 50812191 939478 696195..696998 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 696998 yebC 939478 yebC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388519.2 696195 D 224308 CDS NP_388520.3 255767162 936033 697157..697324 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 697324 yebD 936033 yebD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388520.3 697157 D 224308 CDS NP_388521.2 50812193 939480 697538..698092 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 698092 yebE 939480 yebE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388521.2 697538 D 224308 CDS NP_388523.1 16077709 939351 698092..698289 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 698289 yebG 939351 yebG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388523.1 698092 D 224308 CDS NP_388524.1 16077710 939481 698612..699100 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12787499, 16138311, 9683488; Product type e : enzyme; N5-carboxyaminoimidazole ribonucleotide mutase 699100 purE 939481 purE Bacillus subtilis subsp. subtilis str. 168 N5-carboxyaminoimidazole ribonucleotide mutase NP_388524.1 698612 D 224308 CDS NP_388525.2 255767163 936039 699093..700235 1 NC_000964.3 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; N5-carboxyaminoimidazole ribonucleotide synthase 700235 purK 936039 purK Bacillus subtilis subsp. subtilis str. 168 N5-carboxyaminoimidazole ribonucleotide synthase NP_388525.2 699093 D 224308 CDS NP_388526.1 16077712 936048 700232..701527 1 NC_000964.3 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 701527 purB 936048 purB Bacillus subtilis subsp. subtilis str. 168 adenylosuccinate lyase NP_388526.1 700232 D 224308 CDS NP_388527.1 16077713 939389 701601..702326 1 NC_000964.3 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 702326 purC 939389 purC Bacillus subtilis subsp. subtilis str. 168 phosphoribosylaminoimidazole-succinocarboxamide synthase NP_388527.1 701601 D 224308 CDS NP_388528.1 16077714 936041 702319..702573 1 NC_000964.3 With PurL and PurQ catalyzes the conversion of formylglycinamide ribonucleotide, ATP, and glutamine to formylglycinamidine ribonucleotide, ADP, and glutamate in the fourth step of the purine biosynthetic pathway; hypothetical protein 702573 purS 936041 purS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388528.1 702319 D 224308 CDS NP_388529.1 16077715 938760 702570..703253 1 NC_000964.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 703253 purQ 938760 purQ Bacillus subtilis subsp. subtilis str. 168 phosphoribosylformylglycinamidine synthase NP_388529.1 702570 D 224308 CDS NP_388530.2 255767164 939233 703237..705465 1 NC_000964.3 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; phosphoribosylformylglycinamidine synthase 705465 purL 939233 purL Bacillus subtilis subsp. subtilis str. 168 phosphoribosylformylglycinamidine synthase NP_388530.2 703237 D 224308 CDS NP_388531.2 255767165 936046 705441..706871 1 NC_000964.3 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 706871 purF 936046 purF Bacillus subtilis subsp. subtilis str. 168 amidophosphoribosyltransferase NP_388531.2 705441 D 224308 CDS NP_388532.2 255767166 936044 706973..708013 1 NC_000964.3 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylformylglycinamidine cyclo-ligase 708013 purM 936044 purM Bacillus subtilis subsp. subtilis str. 168 phosphoribosylformylglycinamidine cyclo-ligase NP_388532.2 706973 D 224308 CDS NP_388533.2 255767167 936045 708010..708597 1 NC_000964.3 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 708597 purN 936045 purN Bacillus subtilis subsp. subtilis str. 168 phosphoribosylglycinamide formyltransferase NP_388533.2 708010 D 224308 CDS NP_388534.2 255767168 936053 708594..710132 1 NC_000964.3 involved in de novo purine biosynthesis; bifunctional purine biosynthesis protein PurH 710132 purH 936053 purH Bacillus subtilis subsp. subtilis str. 168 bifunctional purine biosynthesis protein PurH NP_388534.2 708594 D 224308 CDS NP_388535.1 16077721 938741 710148..711416 1 NC_000964.3 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 711416 purD 938741 purD Bacillus subtilis subsp. subtilis str. 168 phosphoribosylamine--glycine ligase NP_388535.1 710148 D 224308 CDS NP_388536.2 255767169 936047 complement(711456..711875) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AsnC family transcriptional regulator 711875 yezC 936047 yezC Bacillus subtilis subsp. subtilis str. 168 AsnC family transcriptional regulator NP_388536.2 711456 R 224308 CDS NP_388537.2 255767170 936051 712019..713293 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid permease 713293 yecA 936051 yecA Bacillus subtilis subsp. subtilis str. 168 amino acid permease NP_388537.2 712019 D 224308 CDS YP_003097691.1 255767171 8302929 complement(713308..713535) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 713535 yezF 8302929 yezF Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097691.1 713308 R 224308 CDS NP_388538.1 16077724 939337 713664..715406 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; adenine deaminase YerA 715406 yerA 939337 yerA Bacillus subtilis subsp. subtilis str. 168 adenine deaminase YerA NP_388538.1 713664 D 224308 CDS NP_388539.1 16077725 936050 715433..716428 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12073041; Product type lp : lipoprotein; lipoprotein 716428 yerB 936050 yerB Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388539.1 715433 D 224308 CDS NP_388540.1 16077726 936049 716431..716745 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 716745 yerC 936049 yerC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388540.1 716431 D 224308 CDS NP_388541.1 16077727 936058 complement(716780..718357) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glutamate synthase large subunit-like protein YerD 718357 yerD 936058 yerD Bacillus subtilis subsp. subtilis str. 168 glutamate synthase large subunit-like protein YerD NP_388541.1 716780 R 224308 CDS NP_388542.1 16077728 936052 718622..719308 1 NC_000964.3 PcrB-like protein; GGGP synthase; member of prenyltransferases that transfer isoprenoid groups to nonisoprenoid acceptors; functions in form GGGP from glycerol-1-phosphate (G-1-P) and geranylgeranyl pyrophosphate (GGPP); important in lipid metabolism and especially important as the ether linkages in archaea are different than those in bacteria; GGGP synthase lies at the branch point for membrane lipid biosynthesis; cytosolic; T acidophilum protein acts as a homodimer while M thermoautotrophicum protein has been reported to function as a pentamer; heptaprenylglyceryl phosphate synthase 719308 pcrB 936052 pcrB Bacillus subtilis subsp. subtilis str. 168 heptaprenylglyceryl phosphate synthase NP_388542.1 718622 D 224308 CDS NP_388543.1 16077729 938747 719370..721589 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 12682299, 14594837, 16267290; Product type e: enzyme; ATP-dependent DNA helicase PcrA 721589 pcrA 938747 pcrA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA helicase PcrA NP_388543.1 719370 D 224308 CDS NP_388544.1 16077730 936056 721613..723619 1 NC_000964.3 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; DNA ligase 723619 ligA 936056 ligA Bacillus subtilis subsp. subtilis str. 168 DNA ligase NP_388544.1 721613 D 224308 CDS NP_388545.1 16077731 938744 723635..724825 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type lp : lipoprotein; lipoprotein 724825 yerH 938744 yerH Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388545.1 723635 D 224308 CDS NP_388546.1 16077732 936055 724987..725997 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 725997 yerI 936055 yerI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388546.1 724987 D 224308 CDS NP_388547.1 16077733 936054 complement(726035..726733) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14708580, 410907, 9043134; Product type ph: phenotype; peptide ABC transporter permease SapB 726733 sapB 936054 sapB Bacillus subtilis subsp. subtilis str. 168 peptide ABC transporter permease SapB NP_388547.1 726035 R 224308 CDS NP_388548.1 16077734 939439 complement(726840..728318) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902719, 14996799, 15849754, 16850406, 17183215, 9701821; Product type t : transporter; osmoregulated proline transporter 728318 opuE 939439 opuE Bacillus subtilis subsp. subtilis str. 168 osmoregulated proline transporter NP_388548.1 726840 R 224308 CDS NP_388549.1 16077735 936063 728732..729022 1 NC_000964.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; glutamyl-tRNA(Gln) amidotransferase subunit C 729022 gatC 936063 gatC Bacillus subtilis subsp. subtilis str. 168 glutamyl-tRNA(Gln) amidotransferase subunit C NP_388549.1 728732 D 224308 CDS NP_388550.1 16077736 938748 729038..730495 1 NC_000964.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; glutamyl-tRNA(Gln) amidotransferase subunit A 730495 gatA 938748 gatA Bacillus subtilis subsp. subtilis str. 168 glutamyl-tRNA(Gln) amidotransferase subunit A NP_388550.1 729038 D 224308 CDS NP_388551.2 50812194 936057 730509..731939 1 NC_000964.3 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 731939 gatB 936057 gatB Bacillus subtilis subsp. subtilis str. 168 aspartyl/glutamyl-tRNA amidotransferase subunit B NP_388551.2 730509 D 224308 CDS NP_388552.1 16077738 939889 complement(731954..732823) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 732823 yerO 939889 yerO Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388552.1 731954 R 224308 CDS NP_388553.1 16077739 938055 732916..736113 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11709341, 15066026, 15941986; Product type t: transporter; surfactin self-resistance transporter 736113 swrC 938055 swrC Bacillus subtilis subsp. subtilis str. 168 surfactin self-resistance transporter NP_388553.1 732916 D 224308 CDS NP_388554.1 16077740 936061 736436..737347 1 NC_000964.3 similar to YegS from E. coli; diacylglycerol kinase 737347 yerQ 936061 yerQ Bacillus subtilis subsp. subtilis str. 168 diacylglycerol kinase NP_388554.1 736436 D 224308 CDS NP_388555.1 16077741 936060 737603..738982 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 23S rRNA (uracil-C(5))-methyltransferase RlmCD 738982 yefA 936060 yefA Bacillus subtilis subsp. subtilis str. 168 23S rRNA (uracil-C(5))-methyltransferase RlmCD NP_388555.1 737603 D 224308 CDS NP_388556.1 16077742 938745 complement(738995..739897) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 739897 yefB 938745 yefB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388556.1 738995 R 224308 CDS NP_388557.2 255767172 938743 739878..740213 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; resolvase homolog YefC 740213 yefC 938743 yefC Bacillus subtilis subsp. subtilis str. 168 resolvase homolog YefC NP_388557.2 739878 D 224308 CDS NP_388558.1 16077744 936059 740288..742927 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA methyltransferase YeeA 742927 yeeA 936059 yeeA Bacillus subtilis subsp. subtilis str. 168 DNA methyltransferase YeeA NP_388558.1 740288 D 224308 CDS NP_388559.2 255767173 936068 742939..744738 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YeeB 744738 yeeB 936068 yeeB Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase YeeB NP_388559.2 742939 D 224308 CDS NP_388560.2 255767174 936062 744851..745999 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin; hypothetical protein 745999 yeeC 936062 yeeC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388560.2 744851 D 224308 CDS NP_388561.1 16077747 938755 complement(746261..746566) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 746566 yeeD 938755 yeeD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388561.1 746261 R 224308 CDS NP_388562.1 16077748 938751 complement(746633..746839) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 746839 yezA 938751 yezA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388562.1 746633 R 224308 CDS YP_003097692.1 255767175 8303066 complement(747079..747534) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 747534 yezG 8303066 yezG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097692.1 747079 R 224308 CDS NP_388563.2 255767176 938753 complement(747554..749563) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 749563 yeeF 938753 yeeF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388563.2 747554 R 224308 CDS NP_388564.2 255767177 938041 749775..750797 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 750797 yeeG 938041 yeeG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388564.2 749775 D 224308 CDS NP_388565.2 255767178 936065 750959..752089 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878; Product type e: enzyme; response regulator aspartate phosphatase H 752089 rapH 936065 rapH Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase H NP_388565.2 750959 D 224308 CDS YP_003097693.1 255767179 8303115 752079..752252 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16553878; Product type pf : factor; inhibitor of regulatory cascade 752252 phrH 8303115 phrH Bacillus subtilis subsp. subtilis str. 168 inhibitor of regulatory cascade YP_003097693.1 752079 D 224308 CDS NP_388566.3 255767180 938749 752412..753131 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator 753131 yeeI 938749 yeeI Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388566.3 752412 D 224308 CDS NP_388567.2 50812196 936073 753265..753702 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 19060142; Product type cp: cell process; spore coat protein YeeK 753702 yeeK 936073 yeeK Bacillus subtilis subsp. subtilis str. 168 spore coat protein YeeK NP_388567.2 753265 D 224308 CDS YP_054572.1 50812197 2914263 753817..754401 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 754401 yezE 2914263 yezE Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator YP_054572.1 753817 D 224308 CDS NP_388568.1 16077754 936064 754480..754923 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 754923 yesE 936064 yesE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388568.1 754480 D 224308 CDS NP_388569.1 16077755 936067 754920..755780 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; oxidoreductase 755780 yesF 936067 yesF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388569.1 754920 D 224308 CDS NP_388570.1 16077756 938758 755907..756155 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat associated protein CotJA 756155 cotJA 938758 cotJA Bacillus subtilis subsp. subtilis str. 168 spore coat associated protein CotJA NP_388570.1 755907 D 224308 CDS NP_388571.2 255767181 936071 756139..756402 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat protein CotJB 756402 cotJB 936071 cotJB Bacillus subtilis subsp. subtilis str. 168 spore coat protein CotJB NP_388571.2 756139 D 224308 CDS NP_388572.1 16077758 938762 756417..756986 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9364920; Product type cp: cell process; spore coat peptide assembly protein CotJC 756986 cotJC 938762 cotJC Bacillus subtilis subsp. subtilis str. 168 spore coat peptide assembly protein CotJC NP_388572.1 756417 D 224308 CDS NP_388573.1 16077759 936070 757111..757653 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YesJ 757653 yesJ 936070 yesJ Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YesJ NP_388573.1 757111 D 224308 CDS NP_388574.2 255767182 936069 757676..757978 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 757978 yesK 936069 yesK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388574.2 757676 D 224308 CDS NP_388575.1 16077761 938754 758093..758722 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 758722 yesL 938754 yesL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388575.1 758093 D 224308 CDS NP_388576.1 16077762 936078 758719..760452 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 760452 yesM 936078 yesM Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388576.1 758719 D 224308 CDS NP_388577.1 16077763 938764 760452..761558 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; transcriptional regulator 761558 yesN 938764 yesN Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388577.1 760452 D 224308 CDS NP_388578.2 255767183 936072 761662..762945 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein; ABC transporter substrate-binding protein 762945 yesO 936072 yesO Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein NP_388578.2 761662 D 224308 CDS NP_388579.1 16077765 936076 762942..763871 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter; ABC transporter permease 763871 yesP 936076 yesP Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_388579.1 762942 D 224308 CDS NP_388580.1 16077766 938765 763875..764765 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17449691; Product type t: transporter; ABC transporter permease 764765 yesQ 938765 yesQ Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_388580.1 763875 D 224308 CDS NP_388581.1 16077767 938759 764781..765815 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonyl hydrolase 765815 yesR 938759 yesR Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonyl hydrolase NP_388581.1 764781 D 224308 CDS NP_388582.1 16077768 936075 765838..768123 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type r: regulator; AraC family transcriptional regulator 768123 yesS 936075 yesS Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388582.1 765838 D 224308 CDS NP_388583.1 16077769 936074 768137..768835 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691, 17957779; Product type e: enzyme; rhamnogalacturonan acetylesterase RhgT 768835 rhgT 936074 rhgT Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonan acetylesterase RhgT NP_388583.1 768137 D 224308 CDS NP_388584.1 16077770 936083 768828..769490 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16781735, 17449691; hypothetical protein 769490 yesU 936083 yesU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388584.1 768828 D 224308 CDS NP_388585.1 16077771 936077 769487..770113 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pm: membrane component; hypothetical protein 770113 yesV 936077 yesV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388585.1 769487 D 224308 CDS NP_388586.1 16077772 938769 770234..772096 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type lp: lipoprotein; rhamnogalacturonan endolyase YesW 772096 yesW 938769 yesW Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonan endolyase YesW NP_388586.1 770234 D 224308 CDS NP_388587.1 16077773 936081 772142..773980 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonan exolyase YesX 773980 yesX 936081 yesX Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonan exolyase YesX NP_388587.1 772142 D 224308 CDS NP_388588.1 16077774 938772 774138..774791 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17449691; Product type e: enzyme; rhamnogalacturonan acetylesterase YesY 774791 yesY 938772 yesY Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonan acetylesterase YesY NP_388588.1 774138 D 224308 CDS NP_388589.1 16077775 936080 774799..776790 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16781735, 17056685, 17449691, 17485082; Product type e: enzyme; beta-galactosidase YesZ 776790 yesZ 936080 yesZ Bacillus subtilis subsp. subtilis str. 168 beta-galactosidase YesZ NP_388589.1 774799 D 224308 CDS NP_388590.2 255767184 938776 776834..779407 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 779407 yetA 938776 yetA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388590.2 776834 D 224308 CDS NP_388591.1 16077777 936079 779529..781037 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921237; Product type lp: lipoprotein; lipoprotein 781037 lplA 936079 lplA Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388591.1 779529 D 224308 CDS NP_388592.1 16077778 936088 781092..782048 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter; ABC transporter permease LplB 782048 lplB 936088 lplB Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease LplB NP_388592.1 781092 D 224308 CDS NP_388593.1 16077779 938767 782062..782949 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10869078, 15849754, 16850406; Product type pt: transporter; ABC transporter permease LplC 782949 lplC 938767 lplC Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease LplC NP_388593.1 782062 D 224308 CDS NP_388594.1 16077780 938770 782958..784298 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; alpha-galacturonidase 784298 lplD 938770 lplD Bacillus subtilis subsp. subtilis str. 168 alpha-galacturonidase NP_388594.1 782958 D 224308 CDS NP_388595.1 16077781 936086 784381..785076 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 785076 yetF 936086 yetF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388595.1 784381 D 224308 CDS NP_388596.1 16077782 936085 complement(785113..785490) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; monooxygenase 785490 yetG 936085 yetG Bacillus subtilis subsp. subtilis str. 168 monooxygenase NP_388596.1 785113 R 224308 CDS NP_388597.1 16077783 938777 complement(785543..785905) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 785905 yetH 938777 yetH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388597.1 785543 R 224308 CDS NP_388600.1 16077786 938773 787715..787882 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 787882 yezD 938773 yezD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388600.1 787715 D 224308 CDS NP_388601.1 16077787 938782 787992..788636 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 788636 yetJ 938782 yetJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388601.1 787992 D 224308 CDS NP_388602.1 16077788 936091 788636..789628 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 789628 yetK 936091 yetK Bacillus subtilis subsp. subtilis str. 168 transporter NP_388602.1 788636 D 224308 CDS NP_388603.1 16077789 938778 complement(789652..790155) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 790155 yetL 938778 yetL Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388603.1 789652 R 224308 CDS NP_388604.1 16077790 936090 790318..791427 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 791427 yetM 936090 yetM Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388604.1 790318 D 224308 CDS NP_388605.1 16077791 936089 complement(791462..792532) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 792532 yetN 936089 yetN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388605.1 791462 R 224308 CDS NP_388606.1 16077792 938784 792682..795867 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11574077, 2544578; Product type pe: enzyme; bifunctional P-450/NADPH-P450 reductase 1 795867 yetO 938784 yetO Bacillus subtilis subsp. subtilis str. 168 bifunctional P-450/NADPH-P450 reductase 1 NP_388606.1 792682 D 224308 CDS NP_388607.2 50812198 936099 796314..798233 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11544192, 15187182, 17434969, 17483484; Product type e: enzyme; lipoteichoic acid synthase 798233 ltaSA 936099 ltaSA Bacillus subtilis subsp. subtilis str. 168 lipoteichoic acid synthase NP_388607.2 796314 D 224308 CDS NP_388608.1 16077794 938779 798469..799233 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glucose-1-phosphate cytidylyltransferase 799233 yfnH 938779 yfnH Bacillus subtilis subsp. subtilis str. 168 glucose-1-phosphate cytidylyltransferase NP_388608.1 798469 D 224308 CDS NP_388609.1 16077795 938783 799303..800208 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; CDP-sugar-dehydratase/epimerase 800208 yfnG 938783 yfnG Bacillus subtilis subsp. subtilis str. 168 CDP-sugar-dehydratase/epimerase NP_388609.1 799303 D 224308 CDS NP_388610.1 16077796 936097 800232..801143 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 801143 yfnF 936097 yfnF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388610.1 800232 D 224308 CDS NP_388611.1 16077797 938781 801172..802350 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YfnE 802350 yfnE 938781 yfnE Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YfnE NP_388611.1 801172 D 224308 CDS NP_388612.1 16077798 936096 802351..803286 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 803286 yfnD 936096 yfnD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388612.1 802351 D 224308 CDS NP_388613.1 16077799 936104 complement(803317..804546) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 804546 yfnC 936104 yfnC Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388613.1 803317 R 224308 CDS NP_388614.1 16077800 936095 complement(804657..805364) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; HAD-hydrolase YfnB 805364 yfnB 936095 yfnB Bacillus subtilis subsp. subtilis str. 168 HAD-hydrolase YfnB NP_388614.1 804657 R 224308 CDS NP_388615.1 16077801 936098 complement(805456..806841) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 2541919; Product type t: transporter; amino acid permease YfnA 806841 yfnA 936098 yfnA Bacillus subtilis subsp. subtilis str. 168 amino acid permease YfnA NP_388615.1 805456 R 224308 CDS NP_388616.1 16077802 938788 807091..808548 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pe : enzyme; aldehyde dehydrogenase YfmT 808548 yfmT 938788 yfmT Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase YfmT NP_388616.1 807091 D 224308 CDS NP_388617.1 16077803 936102 808562..809422 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pr : regulator; sensory transducer protein YfmS 809422 yfmS 936102 yfmS Bacillus subtilis subsp. subtilis str. 168 sensory transducer protein YfmS NP_388617.1 808562 D 224308 CDS NP_388618.1 16077804 936100 809557..811446 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10715006, 16109936; Product type pe: enzyme; ABC transporter ATP-binding protein 811446 yfmR 936100 yfmR Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388618.1 809557 D 224308 CDS NP_388619.1 16077805 938786 811569..812015 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 812015 yfmQ 938786 yfmQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388619.1 811569 D 224308 CDS NP_388620.1 16077806 936101 812140..812562 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator; MerR family transcriptional regulator 812562 yfmP 936101 yfmP Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_388620.1 812140 D 224308 CDS NP_388621.1 16077807 936111 812628..813818 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075, 15849754, 16850406; Product type t: transporter; MFS transporter 813818 yfmO 936111 yfmO Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388621.1 812628 D 224308 CDS NP_388622.1 16077808 938796 814109..814264 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 814264 yfmN 938796 yfmN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388622.1 814109 D 224308 CDS NP_388623.2 255767185 936103 complement(814384..815940) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12486040, 16109936; Product type pt: transporter; ABC transporter ATP-binding protein 815940 yfmM 936103 yfmM Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388623.2 814384 R 224308 CDS NP_388624.1 16077810 938792 816113..817243 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11976317; Product type pe : enzyme; ATP-dependent RNA helicase YfmL 817243 yfmL 938792 yfmL Bacillus subtilis subsp. subtilis str. 168 ATP-dependent RNA helicase YfmL NP_388624.1 816113 D 224308 CDS NP_388625.1 16077811 936108 817311..817757 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YfmK 817757 yfmK 936108 yfmK Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YfmK NP_388625.1 817311 D 224308 CDS NP_388626.1 16077812 936106 complement(817810..818829) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADP-dependent oxidoreductase YfmJ 818829 yfmJ 936106 yfmJ Bacillus subtilis subsp. subtilis str. 168 NADP-dependent oxidoreductase YfmJ NP_388626.1 817810 R 224308 CDS NP_388627.1 16077813 936105 complement(819311..820531) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 820531 yfmI 936105 yfmI Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388627.1 819311 R 224308 CDS NP_388629.1 16077815 938798 820867..822330 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 822330 yfmG 938798 yfmG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388629.1 820867 D 224308 CDS NP_388630.1 16077816 936117 complement(822903..823703) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672620; Product type t: transporter; Fe(3+)-citrate import ATP-binding protein YfmF 823703 yfmF 936117 yfmF Bacillus subtilis subsp. subtilis str. 168 Fe(3+)-citrate import ATP-binding protein YfmF NP_388630.1 822903 R 224308 CDS NP_388631.1 16077817 939692 complement(823716..824717) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16672620, 16850406; Product type t: transporter; Fe(3+)-citrate import system permease protein YfmE 824717 yfmE 939692 yfmE Bacillus subtilis subsp. subtilis str. 168 Fe(3+)-citrate import system permease protein YfmE NP_388631.1 823716 R 224308 CDS NP_388632.1 16077818 936110 complement(824714..825715) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; Fe(3+)-citrate import system permease protein YfmD 825715 yfmD 936110 yfmD Bacillus subtilis subsp. subtilis str. 168 Fe(3+)-citrate import system permease protein YfmD NP_388632.1 824714 R 224308 CDS NP_388633.1 16077819 936114 complement(825787..826734) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter; Fe(3+)-citrate-binding protein YfmC 826734 yfmC 936114 yfmC Bacillus subtilis subsp. subtilis str. 168 Fe(3+)-citrate-binding protein YfmC NP_388633.1 825787 R 224308 CDS NP_388634.1 16077820 938795 complement(826843..827211) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 827211 yfmB 938795 yfmB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388634.1 826843 R 224308 CDS NP_388635.1 16077821 938800 827252..827419 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 827419 yfmA 938800 yfmA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388635.1 827252 D 224308 CDS NP_388636.1 16077822 938794 827455..827802 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12089032; Product type f: factor; general stress protein 17M 827802 yflT 938794 yflT Bacillus subtilis subsp. subtilis str. 168 general stress protein 17M NP_388636.1 827455 D 224308 CDS NP_388637.1 16077823 936113 827993..829255 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12823818, 8262178; Product type e: enzyme; pectate lyase 829255 pel 936113 pel Bacillus subtilis subsp. subtilis str. 168 pectate lyase NP_388637.1 827993 D 224308 CDS NP_388638.1 16077824 936122 829382..830818 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12949159, 15849754, 16850406; Product type t: transporter; malate transporter YflS 830818 yflS 936122 yflS Bacillus subtilis subsp. subtilis str. 168 malate transporter YflS NP_388638.1 829382 D 224308 CDS NP_388639.1 16077825 939687 830945..832573 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type rc: receptor; sensor protein CitS 832573 citS 939687 citS Bacillus subtilis subsp. subtilis str. 168 sensor protein CitS NP_388639.1 830945 D 224308 CDS NP_388640.1 16077826 938806 832545..833225 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972810, 11717295, 12949159, 16842348; Product type r: regulator; transcriptional regulatory protein CitT 833225 citT 938806 citT Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein CitT NP_388640.1 832545 D 224308 CDS NP_388641.2 255767186 936116 833228..834187 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 834187 yflP 936116 yflP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388641.2 833228 D 224308 CDS NP_388642.1 16077828 938801 834383..835684 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12427932, 12533460, 12906362, 12949159, 15849754, 16842348, 16850406; Product type t: transporter; Mg(2+)/citrate complex secondary transporter 835684 citM 938801 citM Bacillus subtilis subsp. subtilis str. 168 Mg(2+)/citrate complex secondary transporter NP_388642.1 834383 D 224308 CDS NP_388643.1 16077829 936120 835740..836534 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10972810; Product type pe : enzyme; hypothetical protein 836534 yflN 936120 yflN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388643.1 835740 D 224308 CDS NP_388644.2 255767187 938802 836653..837744 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11856757, 12220171, 16172391; Product type e: enzyme; nitric oxide synthase oxygenase 837744 nosA 938802 nosA Bacillus subtilis subsp. subtilis str. 168 nitric oxide synthase oxygenase NP_388644.2 836653 D 224308 CDS NP_388645.1 16077831 939684 complement(837735..838010) 1 NC_000964.3 catalyzes the hydrolysis of acylphosphate; acylphosphatase 838010 yflL 939684 yflL Bacillus subtilis subsp. subtilis str. 168 acylphosphatase NP_388645.1 837735 R 224308 CDS NP_388646.1 16077832 936119 838077..838742 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886751; Product type pc : carrier; hypothetical protein 838742 yflK 936119 yflK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388646.1 838077 D 224308 CDS NP_388647.1 16077833 939685 complement(838783..838920) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 838920 yflJ 939685 yflJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388647.1 838783 R 224308 CDS NP_388648.1 16077834 936118 complement(839077..839232) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 839232 yflI 936118 yflI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388648.1 839077 R 224308 CDS NP_388649.1 16077835 936129 complement(839339..839653) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368; hypothetical protein 839653 yflH 936129 yflH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388649.1 839339 R 224308 CDS NP_388650.1 16077836 936121 complement(839735..840484) 1 NC_000964.3 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mnin Bacillus subtilis the protein in this cluster is considered non-essential; methionine aminopeptidase 2 840484 yflG 936121 yflG Bacillus subtilis subsp. subtilis str. 168 methionine aminopeptidase 2 NP_388650.1 839735 R 224308 CDS NP_388651.1 16077837 938807 840656..842014 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 8246840; Product type t: transporter; PTS system N-acetylglucosamine-specific EIICB component 842014 nagP 938807 nagP Bacillus subtilis subsp. subtilis str. 168 PTS system N-acetylglucosamine-specific EIICB component NP_388651.1 840656 D 224308 CDS NP_388652.1 16077838 939200 complement(842047..843996) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10658653; Product type pe : enzyme; lipoteichoic acid synthase 843996 yflE 939200 yflE Bacillus subtilis subsp. subtilis str. 168 lipoteichoic acid synthase NP_388652.1 842047 R 224308 CDS NP_388653.1 16077839 936125 844097..844234 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 844234 yflD 936125 yflD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388653.1 844097 D 224308 CDS NP_388655.2 255767188 936124 844253..844645 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 844645 yflB 936124 yflB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388655.2 844253 D 224308 CDS NP_388656.1 16077842 939686 844770..846185 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 846185 yflA 939686 yflA Bacillus subtilis subsp. subtilis str. 168 transporter NP_388656.1 844770 D 224308 CDS NP_388657.1 16077843 936135 complement(846182..847258) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component; spore germination protein YfkT 847258 yfkT 936135 yfkT Bacillus subtilis subsp. subtilis str. 168 spore germination protein YfkT NP_388657.1 846182 R 224308 CDS NP_388658.1 16077844 936123 complement(847282..847482) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 847482 yfkS 936123 yfkS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388658.1 847282 R 224308 CDS NP_388659.1 16077845 936126 complement(847498..848652) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; spore germination protein YfkR 848652 yfkR 936126 yfkR Bacillus subtilis subsp. subtilis str. 168 spore germination protein YfkR NP_388659.1 847498 R 224308 CDS NP_388660.1 16077846 939688 complement(848633..850174) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; membrane protein 850174 yfkQ 939688 yfkQ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388660.1 848633 R 224308 CDS NP_388661.1 16077847 939188 850367..851779 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8755887, 8917076, 8969503; Product type t: transporter; PTS system trehalose-specific EIIBC component 851779 treP 939188 treP Bacillus subtilis subsp. subtilis str. 168 PTS system trehalose-specific EIIBC component NP_388661.1 850367 D 224308 CDS NP_388662.1 16077848 939690 851850..853535 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7651129, 7751281, 8755887, 8917076, 9701821; Product type e: enzyme; trehalose-6-phosphate hydrolase 853535 treA 939690 treA Bacillus subtilis subsp. subtilis str. 168 trehalose-6-phosphate hydrolase NP_388662.1 851850 D 224308 CDS NP_388663.1 16077849 936133 853556..854272 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8755887, 9829827; Product type r: regulator; trehalose operon transcriptional repressor 854272 treR 936133 treR Bacillus subtilis subsp. subtilis str. 168 trehalose operon transcriptional repressor NP_388663.1 853556 D 224308 CDS NP_388664.1 16077850 939189 854412..855077 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme; NAD(P)H nitroreductase YfkO 855077 yfkO 939189 yfkO Bacillus subtilis subsp. subtilis str. 168 NAD(P)H nitroreductase YfkO NP_388664.1 854412 D 224308 CDS NP_388665.1 16077851 936131 complement(855114..859502) 1 NC_000964.3 in Escherichia coli this is a periplasmic enzyme while in gram positive organisms it may be anchored at the cell surface; this protein appears to consist of a dimer fusion; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate; nucleotide phosphoesterase 859502 yfkN 936131 yfkN Bacillus subtilis subsp. subtilis str. 168 nucleotide phosphoesterase NP_388665.1 855114 R 224308 CDS NP_388666.1 16077852 938808 859745..860263 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 12354229, 16181642, 17257049, 17933887; Product type f: factor; general stress protein 18 860263 yfkM 938808 yfkM Bacillus subtilis subsp. subtilis str. 168 general stress protein 18 NP_388666.1 859745 D 224308 CDS NP_388667.1 16077853 939689 complement(860303..861493) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16828913, 16850406; Product type t : transporter; MFS transporter 861493 yfkL 939689 yfkL Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388667.1 860303 R 224308 CDS NP_388668.1 16077854 936130 complement(861586..861801) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 861801 yfkK 936130 yfkK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388668.1 861586 R 224308 CDS NP_388669.1 16077855 939191 862004..862474 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme; low molecular weight protein-tyrosine-phosphatase YfkJ 862474 yfkJ 939191 yfkJ Bacillus subtilis subsp. subtilis str. 168 low molecular weight protein-tyrosine-phosphatase YfkJ NP_388669.1 862004 D 224308 CDS NP_388670.1 16077856 939691 862492..862812 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210; hypothetical protein 862812 yfkI 939691 yfkI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388670.1 862492 D 224308 CDS NP_388671.1 16077857 936134 862836..863663 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222749, 12794188, 15849754, 16850406; Product type pe: enzyme; ribonuclease-like protein YfkH 863663 yfkH 936134 yfkH Bacillus subtilis subsp. subtilis str. 168 ribonuclease-like protein YfkH NP_388671.1 862836 D 224308 CDS NP_388672.1 16077858 939190 complement(863862..865037) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 865037 yfkF 939190 yfkF Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388672.1 863862 R 224308 CDS NP_388673.1 16077859 939693 865205..866260 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; cation exchanger YfkE 866260 yfkE 939693 yfkE Bacillus subtilis subsp. subtilis str. 168 cation exchanger YfkE NP_388673.1 865205 D 224308 CDS NP_388674.1 16077860 936138 866331..867125 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 867125 yfkD 936138 yfkD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388674.1 866331 D 224308 CDS NP_388675.1 16077861 936137 complement(867164..868006) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; MscS family protein YfkC 868006 yfkC 936137 yfkC Bacillus subtilis subsp. subtilis str. 168 MscS family protein YfkC NP_388675.1 867164 R 224308 CDS NP_388677.2 255767189 938812 complement(868007..869128) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; radical SAM protein YfkA 869128 yfkA 938812 yfkA Bacillus subtilis subsp. subtilis str. 168 radical SAM protein YfkA NP_388677.2 868007 R 224308 CDS NP_388678.1 16077864 939694 869273..869458 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 869458 yfjT 939694 yfjT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388678.1 869273 D 224308 CDS NP_388679.1 16077865 936136 869559..870350 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15687192; Product type e: enzyme; polysaccharide deacetylase PdaA 870350 pdaA 936136 pdaA Bacillus subtilis subsp. subtilis str. 168 polysaccharide deacetylase PdaA NP_388679.1 869559 D 224308 CDS NP_388680.2 255767190 939198 complement(870388..871248) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 871248 yfjR 939198 yfjR Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388680.2 870388 R 224308 CDS NP_388681.1 16077867 936159 complement(871347..872306) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter; metal ion transporter YfjQ 872306 yfjQ 936159 yfjQ Bacillus subtilis subsp. subtilis str. 168 metal ion transporter YfjQ NP_388681.1 871347 R 224308 CDS NP_388682.1 16077868 939192 872425..873288 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA-3-methyladenine glycosylase YfjP 873288 yfjP 939192 yfjP Bacillus subtilis subsp. subtilis str. 168 DNA-3-methyladenine glycosylase YfjP NP_388682.1 872425 D 224308 CDS NP_388683.1 16077869 936146 873402..874802 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA methyltransferase YfjO 874802 yfjO 936146 yfjO Bacillus subtilis subsp. subtilis str. 168 RNA methyltransferase YfjO NP_388683.1 873402 D 224308 CDS YP_003097694.1 255767191 8302973 875428..875694 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 875694 yfzA 8302973 yfzA Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097694.1 875428 D 224308 CDS NP_388684.1 16077870 936154 876426..877403 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11983710; Product type e: enzyme; tRNA-dihydrouridine synthase 2 877403 dusC 936154 dusC Bacillus subtilis subsp. subtilis str. 168 tRNA-dihydrouridine synthase 2 NP_388684.1 876426 D 224308 CDS NP_388685.1 16077871 939698 877599..878051 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 878051 yfjM 939698 yfjM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388685.1 877599 D 224308 CDS NP_388686.1 16077872 939202 878081..878770 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 878770 yfjL 939202 yfjL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388686.1 878081 D 224308 CDS NP_388687.1 16077873 936152 879002..880003 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha 880003 acoA 936152 acoA Bacillus subtilis subsp. subtilis str. 168 acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit alpha NP_388687.1 879002 D 224308 CDS NP_388688.1 16077874 939697 880007..881035 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type e: enzyme; acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta 881035 acoB 939697 acoB Bacillus subtilis subsp. subtilis str. 168 acetoin:2,6-dichlorophenolindophenol oxidoreductase subunit beta NP_388688.1 880007 D 224308 CDS NP_388689.1 16077875 936147 881049..882245 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 11274109; Product type e: enzyme; dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system 882245 acoC 936147 acoC Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyllysine-residue acetyltransferase component of acetoin cleaving system NP_388689.1 881049 D 224308 CDS NP_388690.1 16077876 939702 882266..883642 1 NC_000964.3 E3 component of acetoin cleaving system; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase 883642 acoL 939702 acoL Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyl dehydrogenase NP_388690.1 882266 D 224308 CDS NP_388691.1 16077877 936148 883758..885575 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109; Product type r: regulator; acetoin dehydrogenase operon transcriptional activator AcoR 885575 acoR 936148 acoR Bacillus subtilis subsp. subtilis str. 168 acetoin dehydrogenase operon transcriptional activator AcoR NP_388691.1 883758 D 224308 CDS NP_388692.1 16077878 939208 885629..885808 1 NC_000964.3 SASP H; spore coat; expressed in forespore compartment; small acid-soluble spore protein H 885808 sspH 939208 sspH Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein H NP_388692.1 885629 D 224308 CDS NP_388693.1 16077879 939201 complement(885844..886173) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 886173 yfjF 939201 yfjF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388693.1 885844 R 224308 CDS NP_388694.1 16077880 939699 complement(886223..886681) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 886681 yfjE 939699 yfjE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388694.1 886223 R 224308 CDS NP_388695.1 16077881 936158 complement(886775..887332) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; lipoprotein 887332 yfjD 936158 yfjD Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388695.1 886775 R 224308 CDS NP_388696.1 16077882 939231 complement(887364..888131) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 888131 yfjC 939231 yfjC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388696.1 887364 R 224308 CDS NP_388697.1 16077883 939700 complement(888143..889366) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 889366 yfjB 939700 yfjB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388697.1 888143 R 224308 CDS NP_388698.1 16077884 936160 complement(889372..889686) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 889686 yfjA 936160 yfjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388698.1 889372 R 224308 CDS NP_388699.1 16077885 936161 890022..891371 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10329789, 11489864, 15341727, 15670594, 17676871, 9765262; Product type e : enzyme; maltose-6'-phosphate glucosidase 891371 malA 936161 malA Bacillus subtilis subsp. subtilis str. 168 maltose-6'-phosphate glucosidase NP_388699.1 890022 D 224308 CDS NP_388700.1 16077886 939205 891436..892200 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489864; Product type r: regulator; RpiR family transcriptional regulator 892200 malR 939205 malR Bacillus subtilis subsp. subtilis str. 168 RpiR family transcriptional regulator NP_388700.1 891436 D 224308 CDS NP_388701.1 16077887 939713 892215..893798 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; PTS maltose transporter subunit IIBC 893798 malP 939713 malP Bacillus subtilis subsp. subtilis str. 168 PTS maltose transporter subunit IIBC NP_388701.1 892215 D 224308 CDS NP_388702.1 16077888 936163 893904..895625 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter; ABC transporter ATP-binding protein 895625 malQ 936163 malQ Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388702.1 893904 D 224308 CDS NP_388703.1 16077889 936167 895619..897433 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 897433 yfiC 936167 yfiC Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388703.1 895619 D 224308 CDS NP_388704.1 16077890 939204 897588..897992 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17407181; Product type e: enzyme; oxidoreductase 897992 catD 939204 catD Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388704.1 897588 D 224308 CDS NP_388705.2 255767192 936164 898010..898867 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17407181; Product type e: enzyme; catechol-2,3-dioxygenase 898867 catE 936164 catE Bacillus subtilis subsp. subtilis str. 168 catechol-2,3-dioxygenase NP_388705.2 898010 D 224308 CDS NP_388706.1 16077892 939704 898961..899905 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 899905 yfiF 939704 yfiF Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388706.1 898961 D 224308 CDS NP_388707.1 16077893 939710 900080..901528 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transporter 901528 yfiG 939710 yfiG Bacillus subtilis subsp. subtilis str. 168 metabolite transporter NP_388707.1 900080 D 224308 CDS NP_388708.1 16077894 939706 901555..902496 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 902496 yfiH 939706 yfiH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388708.1 901555 D 224308 CDS NP_388709.1 16077895 936177 902506..903687 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 903687 yfiI 936177 yfiI Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388709.1 902506 D 224308 CDS NP_388710.1 16077896 936171 903811..905013 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type rc: receptor; sensor histidine kinase 905013 yfiJ 936171 yfiJ Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388710.1 903811 D 224308 CDS NP_388711.1 16077897 939209 905010..905672 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12618459; Product type r: regulator; transcriptional regulator 905672 yfiK 939209 yfiK Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388711.1 905010 D 224308 CDS NP_388712.2 255767193 936175 905816..906751 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 906751 yfiL 936175 yfiL Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388712.2 905816 D 224308 CDS NP_388713.1 16077899 939210 906764..907954 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YfiM 907954 yfiM 939210 yfiM Bacillus subtilis subsp. subtilis str. 168 transport permease YfiM NP_388713.1 906764 D 224308 CDS NP_388714.1 16077900 939705 907968..909125 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YfiN 909125 yfiN 939705 yfiN Bacillus subtilis subsp. subtilis str. 168 transport permease YfiN NP_388714.1 907968 D 224308 CDS NP_388715.1 16077901 936174 complement(909198..909746) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11073918, 17295427, 18326577; Product type r: regulator; negative transcription regulator PadR 909746 padR 936174 padR Bacillus subtilis subsp. subtilis str. 168 negative transcription regulator PadR NP_388715.1 909198 R 224308 CDS NP_388716.1 16077902 939715 910019..910651 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11029590, 10913700; Product type e: enzyme; extracellular esterase EstB 910651 estB 939715 estB Bacillus subtilis subsp. subtilis str. 168 extracellular esterase EstB NP_388716.1 910019 D 224308 CDS NP_388717.1 16077903 936185 910840..911928 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane-bound acyltransferase YfiQ 911928 yfiQ 936185 yfiQ Bacillus subtilis subsp. subtilis str. 168 membrane-bound acyltransferase YfiQ NP_388717.1 910840 D 224308 CDS NP_388718.1 16077904 936176 complement(911964..912581) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16862575; Product type r: regulator; TetR family transcriptional regulator 912581 yfiR 936176 yfiR Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388718.1 911964 R 224308 CDS NP_388719.1 16077905 939219 complement(912547..913800) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 16862575; Product type pt: transporter; MFS transporter 913800 yfiS 939219 yfiS Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388719.1 912547 R 224308 CDS NP_388720.1 16077906 939711 913924..914460 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15581359; Product type e: enzyme; metal-dependent hydrolase YfiT 914460 yfiT 939711 yfiT Bacillus subtilis subsp. subtilis str. 168 metal-dependent hydrolase YfiT NP_388720.1 913924 D 224308 CDS NP_388721.1 16077907 936182 complement(914457..916013) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 916013 yfiU 936182 yfiU Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388721.1 914457 R 224308 CDS NP_388722.1 16077908 939218 complement(916124..916606) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 916606 yfiV 939218 yfiV Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388722.1 916124 R 224308 CDS YP_003097695.1 255767194 8303094 916778..919348 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14702396, 15849754, 16299297, 16850406, 17042784, 2490162; Product type f: factor; phosphatidylglycerol lysyltransferase 919348 mprF 8303094 mprF Bacillus subtilis subsp. subtilis str. 168 phosphatidylglycerol lysyltransferase YP_003097695.1 916778 D 224308 CDS NP_388725.1 16077911 939206 complement(919366..920343) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; siderophore-binding lipoprotein YfiY 920343 yfiY 939206 yfiY Bacillus subtilis subsp. subtilis str. 168 siderophore-binding lipoprotein YfiY NP_388725.1 919366 R 224308 CDS NP_388726.1 16077912 936179 920474..921475 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; siderophore transport system permease protein YfiZ 921475 yfiZ 936179 yfiZ Bacillus subtilis subsp. subtilis str. 168 siderophore transport system permease protein YfiZ NP_388726.1 920474 D 224308 CDS NP_388727.1 16077913 939714 921472..922503 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406; Product type t: transporter; siderophore transport system permease protein YfhA 922503 yfhA 939714 yfhA Bacillus subtilis subsp. subtilis str. 168 siderophore transport system permease protein YfhA NP_388727.1 921472 D 224308 CDS NP_388728.1 16077914 936191 922618..923499 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isomerase 923499 yfhB 936191 yfhB Bacillus subtilis subsp. subtilis str. 168 isomerase NP_388728.1 922618 D 224308 CDS NP_388729.1 16077915 939221 923587..924171 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme; NAD(P)H nitroreductase YfhC 924171 yfhC 939221 yfhC Bacillus subtilis subsp. subtilis str. 168 NAD(P)H nitroreductase YfhC NP_388729.1 923587 D 224308 CDS NP_388730.1 16077916 939709 complement(924210..924401) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 924401 yfhD 939709 yfhD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388730.1 924210 R 224308 CDS NP_388731.1 16077917 936184 complement(924468..924578) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 924578 yfhE 936184 yfhE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388731.1 924468 R 224308 CDS NP_388732.1 16077918 939217 complement(924633..925544) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; epimerase family protein YfhF 925544 yfhF 939217 yfhF Bacillus subtilis subsp. subtilis str. 168 epimerase family protein YfhF NP_388732.1 924633 R 224308 CDS NP_388733.1 16077919 939727 925633..926427 1 NC_000964.3 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; regulatory protein RecX 926427 recX 939727 recX Bacillus subtilis subsp. subtilis str. 168 regulatory protein RecX NP_388733.1 925633 D 224308 CDS NP_388734.1 16077920 936189 926429..926743 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 926743 yfhH 936189 yfhH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388734.1 926429 D 224308 CDS NP_388735.1 16077921 939712 926886..928079 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 928079 yfhI 939712 yfhI Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388735.1 926886 D 224308 CDS YP_054573.1 50812199 2914224 complement(928112..928264) 1 NC_000964.3 SASP K; found in the forespore compartment; small acid-soluble spore protein K 928264 sspK 2914224 sspK Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein K YP_054573.1 928112 R 224308 CDS NP_388736.1 16077922 936188 928389..928658 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 928658 yfhJ 936188 yfhJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388736.1 928389 D 224308 CDS NP_388737.1 16077923 939215 928803..929321 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 929321 yfhK 939215 yfhK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388737.1 928803 D 224308 CDS NP_388738.1 16077924 939228 929406..929738 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16629676; Product type f: factor; hypothetical protein 929738 yfhL 939228 yfhL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388738.1 929406 D 224308 CDS NP_388739.1 16077925 936187 929725..930585 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YfhM 930585 yfhM 936187 yfhM Bacillus subtilis subsp. subtilis str. 168 AB hydrolase superfamily protein YfhM NP_388739.1 929725 D 224308 CDS NP_388740.1 16077926 939717 930818..931807 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8921856, 9636707; Product type pe: enzyme; glycosyltransferase CsbB 931807 csbB 939717 csbB Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase CsbB NP_388740.1 930818 D 224308 CDS NP_388741.2 255767195 936195 931879..934464 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 934464 yfhO 936195 yfhO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388741.2 931879 D 224308 CDS NP_388742.1 16077928 936190 complement(934457..935440) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10524235, 15849754, 16850406; Product type pe: enzyme; hypothetical protein 935440 yfhP 936190 yfhP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388742.1 934457 R 224308 CDS NP_388743.1 16077929 939222 935656..936765 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10463184; Product type e: enzyme; A/G-specific adenine glycosylase YfhQ 936765 yfhQ 939222 yfhQ Bacillus subtilis subsp. subtilis str. 168 A/G-specific adenine glycosylase YfhQ NP_388743.1 935656 D 224308 CDS NP_388744.1 16077930 936193 complement(936773..936997) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10463184; hypothetical protein 936997 yfhS 936193 yfhS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388744.1 936773 R 224308 CDS NP_388745.1 16077931 939223 937079..937831 1 NC_000964.3 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-[acyl-carrier-protein] reductase [NADPH] FabL 937831 fabL 939223 fabL Bacillus subtilis subsp. subtilis str. 168 enoyl-[acyl-carrier-protein] reductase [NADPH] FabL NP_388745.1 937079 D 224308 CDS NP_388746.1 16077932 939716 937900..938154 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1744043, 7592342, 9540829; Product type cp: cell process; small acid-soluble spore protein gamma-type 938154 sspE 939716 sspE Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein gamma-type NP_388746.1 937900 D 224308 CDS NP_388747.1 16077933 939220 938243..938587 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 938587 ygaB 939220 ygaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388747.1 938243 D 224308 CDS NP_388748.3 255767196 936192 938731..939261 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 939261 ygaC 936192 ygaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388748.3 938731 D 224308 CDS NP_388749.1 16077935 936200 939322..941091 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 941091 ygaD 936200 ygaD Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388749.1 939322 D 224308 CDS NP_388750.1 16077936 939721 complement(941168..942229) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 942229 ygaE 939721 ygaE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388750.1 941168 R 224308 CDS NP_388751.3 255767197 936194 complement(942449..943738) 1 NC_000964.3 converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; glutamate-1-semialdehyde 2,1-aminomutase 943738 gsaB 936194 gsaB Bacillus subtilis subsp. subtilis str. 168 glutamate-1-semialdehyde 2,1-aminomutase NP_388751.3 942449 R 224308 CDS YP_054574.1 50812202 2914207 943891..944364 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10644761, 11349039, 12950915; Product type pe: enzyme; peroxiredoxin YgaF 944364 ygaF 2914207 ygaF Bacillus subtilis subsp. subtilis str. 168 peroxiredoxin YgaF YP_054574.1 943891 D 224308 CDS NP_388753.1 16077938 939227 944487..944924 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1580225, 16541078, 16925555; Product type r: regulator; peroxide operon regulator 944924 perR 939227 perR Bacillus subtilis subsp. subtilis str. 168 peroxide operon regulator NP_388753.1 944487 D 224308 CDS YP_054575.1 50812203 2914245 complement(944959..945312) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 945312 ygzB 2914245 ygzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054575.1 944959 R 224308 CDS NP_388755.1 16077940 936198 945520..946404 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 946404 ygxA 936198 ygxA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388755.1 945520 D 224308 CDS NP_388756.2 255767198 939725 complement(953373..954149) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9795118; Product type r : regulator; sporulation-control protein spo0M 954149 spo0M 939725 spo0M Bacillus subtilis subsp. subtilis str. 168 sporulation-control protein spo0M NP_388756.2 953373 R 224308 CDS NP_388757.2 255767199 936205 954291..954494 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 954494 ygzA 936205 ygzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388757.2 954291 D 224308 CDS YP_003097696.1 255767200 8302962 complement(954579..954851) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; spore coat protein F 954851 ygzC 8302962 ygzC Bacillus subtilis subsp. subtilis str. 168 spore coat protein F YP_003097696.1 954579 R 224308 CDS NP_388758.2 255767201 939241 954893..955585 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YgaJ 955585 ygaJ 939241 ygaJ Bacillus subtilis subsp. subtilis str. 168 peptidase YgaJ NP_388758.2 954893 D 224308 CDS NP_388759.2 255767202 939745 955895..957667 1 NC_000964.3 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; phosphomethylpyrimidine synthase 957667 thiC 939745 thiC Bacillus subtilis subsp. subtilis str. 168 phosphomethylpyrimidine synthase NP_388759.2 955895 D 224308 CDS NP_388760.2 255767203 939245 complement(957705..959060) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8972604; Product type pe : enzyme; FAD-linked oxidoreductase YgaK 959060 ygaK 939245 ygaK Bacillus subtilis subsp. subtilis str. 168 FAD-linked oxidoreductase YgaK NP_388760.2 957705 R 224308 CDS NP_388761.1 16077946 936207 959290..959508 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1479343, 16321961, 8323536; Product type r: regulator; transcriptional regulator 959508 senS 936207 senS Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388761.1 959290 D 224308 CDS NP_388762.2 255767204 939240 complement(959535..960986) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12486061, 16535198; Product type e: enzyme; vegetative catalase 960986 katA 939240 katA Bacillus subtilis subsp. subtilis str. 168 vegetative catalase NP_388762.2 959535 R 224308 CDS NP_388763.3 255767205 939730 961394..962161 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type t: transporter; aliphatic sulfonates import ATP-binding protein SsuB 962161 ssuB 939730 ssuB Bacillus subtilis subsp. subtilis str. 168 aliphatic sulfonates import ATP-binding protein SsuB NP_388763.3 961394 D 224308 CDS NP_388764.1 16077949 936215 962179..963177 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11390694, 16513748, 16885442, 9782504; Product type f: factor; aliphatic sulfonates-binding protein 963177 ssuA 936215 ssuA Bacillus subtilis subsp. subtilis str. 168 aliphatic sulfonates-binding protein NP_388764.1 962179 D 224308 CDS NP_388765.1 16077950 936208 963174..964004 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 15849754, 16513748, 16850406, 16885442, 9782504; Product type t : transporter; aliphatic sulfonates transport permease protein SsuC 964004 ssuC 936208 ssuC Bacillus subtilis subsp. subtilis str. 168 aliphatic sulfonates transport permease protein SsuC NP_388765.1 963174 D 224308 CDS NP_388766.2 50812205 939733 964027..965157 1 NC_000964.3 catalyzes the release of sulfite from alkanesulfonates; alkanesulfonate monooxygenase 965157 ssuD 939733 ssuD Bacillus subtilis subsp. subtilis str. 168 alkanesulfonate monooxygenase NP_388766.2 964027 D 224308 CDS NP_388767.1 16077952 939249 965261..965797 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 965797 ygaN 939249 ygaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388767.1 965261 D 224308 CDS NP_388768.1 16077953 936213 965909..966178 1 NC_000964.3 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; alternate 30S ribosomal protein S14 966178 rpsN 936213 rpsN Bacillus subtilis subsp. subtilis str. 168 alternate 30S ribosomal protein S14 NP_388768.1 965909 D 224308 CDS NP_388769.1 16077954 939244 complement(966196..966669) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; lipoprotein 966669 ygaO 939244 ygaO Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388769.1 966196 R 224308 CDS YP_003097697.1 255767206 8303098 complement(966671..966871) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 966871 ygzD 8303098 ygzD Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator YP_003097697.1 966671 R 224308 CDS NP_388771.1 16077955 939736 complement(967229..967852) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 967852 yhzB 939736 yhzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388771.1 967229 R 224308 CDS NP_388772.2 255767207 939243 967935..969095 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; epoxyqueuosine reductase 969095 yhbA 939243 yhbA Bacillus subtilis subsp. subtilis str. 168 epoxyqueuosine reductase NP_388772.2 967935 D 224308 CDS NP_388773.1 16077957 936223 969162..970097 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 970097 yhbB 936223 yhbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388773.1 969162 D 224308 CDS NP_388774.2 255767208 939735 970135..970617 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299; Product type pe : enzyme; tRNA (cytidine(34)-2'-O)-methyltransferase 970617 cspR 939735 cspR Bacillus subtilis subsp. subtilis str. 168 tRNA (cytidine(34)-2'-O)-methyltransferase NP_388774.2 970135 D 224308 CDS NP_388775.1 16077959 936214 970667..971383 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 971383 yhbD 936214 yhbD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388775.1 970667 D 224308 CDS NP_388776.1 16077960 939252 971374..972087 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 972087 yhbE 939252 yhbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388776.1 971374 D 224308 CDS NP_388777.2 255767209 936219 972099..972806 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 972806 yhbF 936219 yhbF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388777.2 972099 D 224308 CDS NP_388778.1 16077962 939250 973156..975051 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922, 8626065; Product type e: enzyme; serine protein kinase PrkA 975051 prkA 939250 prkA Bacillus subtilis subsp. subtilis str. 168 serine protein kinase PrkA NP_388778.1 973156 D 224308 CDS NP_388779.1 16077963 936217 975231..976409 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11988534, 12662922, 14523133; Product type f: factor; stress response UPF0229 protein YhbH 976409 yhbH 936217 yhbH Bacillus subtilis subsp. subtilis str. 168 stress response UPF0229 protein YhbH NP_388779.1 975231 D 224308 CDS NP_388780.1 16077964 939247 976569..977033 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 977033 yhbI 939247 yhbI Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388780.1 976569 D 224308 CDS NP_388781.1 16077965 936216 977069..977734 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; efflux system component YhbJ 977734 yhbJ 936216 yhbJ Bacillus subtilis subsp. subtilis str. 168 efflux system component YhbJ NP_388781.1 977069 D 224308 CDS NP_388782.1 16077966 936235 977775..979373 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 979373 yhcA 936235 yhcA Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388782.1 977775 D 224308 CDS NP_388783.1 16077967 939734 979396..979926 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15754243; Product type pe : enzyme; hypothetical protein 979926 yhcB 939734 yhcB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388783.1 979396 D 224308 CDS NP_388784.1 16077968 936220 979939..980313 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 980313 yhcC 936220 yhcC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388784.1 979939 D 224308 CDS NP_388785.1 16077969 939260 980313..980468 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 980468 yhcD 939260 yhcD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388785.1 980313 D 224308 CDS NP_388786.1 16077970 939256 980473..981234 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 981234 yhcE 939256 yhcE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388786.1 980473 D 224308 CDS NP_388787.1 16077971 936231 981237..981602 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 981602 yhcF 936231 yhcF Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388787.1 981237 D 224308 CDS NP_388788.1 16077972 939738 981604..982302 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pt : transporter; spermidine/putrescine ABC transporter ATP-binding protein 982302 yhcG 939738 yhcG Bacillus subtilis subsp. subtilis str. 168 spermidine/putrescine ABC transporter ATP-binding protein NP_388788.1 981604 D 224308 CDS NP_388789.1 16077973 936229 982319..983236 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467, 7476193; Product type pt: transporter; ABC transporter ATP-binding protein 983236 yhcH 936229 yhcH Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388789.1 982319 D 224308 CDS NP_388790.1 16077974 939251 983229..984170 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 15870467, 16850406; Product type pt: transporter; hypothetical protein 984170 yhcI 939251 yhcI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388790.1 983229 D 224308 CDS NP_388791.1 16077975 936224 complement(984262..984465) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12493834, 16352840; Product type f: factor; cold shock protein CspB 984465 cspB 936224 cspB Bacillus subtilis subsp. subtilis str. 168 cold shock protein CspB NP_388791.1 984262 R 224308 CDS NP_388792.2 255767210 939261 984901..985731 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 985731 yhcJ 939261 yhcJ Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388792.2 984901 D 224308 CDS NP_388793.1 16077977 936246 complement(985734..986813) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; diguanylate cyclase 986813 dgcK 936246 dgcK Bacillus subtilis subsp. subtilis str. 168 diguanylate cyclase NP_388793.1 985734 R 224308 CDS NP_388794.1 16077978 939257 986986..988377 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15262924, 15849754, 16850406; Product type t: transporter; L-cystine uptake protein TcyP 988377 tcyP 939257 tcyP Bacillus subtilis subsp. subtilis str. 168 L-cystine uptake protein TcyP NP_388794.1 986986 D 224308 CDS NP_388795.1 16077979 939279 complement(988417..988872) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 988872 yhcM 939279 yhcM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388795.1 988417 R 224308 CDS NP_388796.2 255767211 939739 989022..989591 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9611260; Product type lp : lipoprotein; lipoprotein 989591 yhcN 939739 yhcN Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_388796.2 989022 D 224308 CDS NP_388797.2 255767212 936243 989712..990680 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 990680 yhcO 936243 yhcO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388797.2 989712 D 224308 CDS NP_388799.1 16077983 936236 complement(990612..991265) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; spore coat protein F 991265 yhcQ 936236 yhcQ Bacillus subtilis subsp. subtilis str. 168 spore coat protein F NP_388799.1 990612 R 224308 CDS NP_388800.1 16077984 936241 991348..995001 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15292138; Product type e: enzyme; endonuclease 995001 yhcR 936241 yhcR Bacillus subtilis subsp. subtilis str. 168 endonuclease NP_388800.1 991348 D 224308 CDS NP_388801.1 16077985 939748 994998..995594 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823805; Product type pe : enzyme; hypothetical protein 995594 yhcS 939748 yhcS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388801.1 994998 D 224308 CDS NP_388802.2 255767213 936253 complement(995624..996532) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9814761; Product type pe : enzyme; RNA pseudouridine synthase YhcT 996532 yhcT 936253 yhcT Bacillus subtilis subsp. subtilis str. 168 RNA pseudouridine synthase YhcT NP_388802.2 995624 R 224308 CDS NP_388803.2 255767214 936261 996643..997038 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 997038 yhcU 936261 yhcU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388803.2 996643 D 224308 CDS NP_388804.1 16077988 939740 997175..997597 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; CBS domain-containing protein YhcV 997597 yhcV 939740 yhcV Bacillus subtilis subsp. subtilis str. 168 CBS domain-containing protein YhcV NP_388804.1 997175 D 224308 CDS NP_388805.1 16077989 936244 997724..998386 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 998386 yhcW 936244 yhcW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388805.1 997724 D 224308 CDS NP_388806.2 255767215 939265 998402..999943 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase 999943 yhcX 939265 yhcX Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_388806.2 998402 D 224308 CDS NP_388807.2 255767216 939742 1000364..1001716 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11082195; Product type pe : enzyme; aminotransferase YhxA 1001716 yhxA 939742 yhxA Bacillus subtilis subsp. subtilis str. 168 aminotransferase YhxA NP_388807.2 1000364 D 224308 CDS NP_388808.1 16077992 936251 1001744..1002322 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549; Product type r: regulator; glycerol uptake operon antiterminator regulatory protein 1002322 glpP 936251 glpP Bacillus subtilis subsp. subtilis str. 168 glycerol uptake operon antiterminator regulatory protein NP_388808.1 1001744 D 224308 CDS NP_388809.1 16077993 939266 1002501..1003325 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11929549, 15849754, 16850406; Product type t: transporter; glycerol uptake facilitator protein 1003325 glpF 939266 glpF Bacillus subtilis subsp. subtilis str. 168 glycerol uptake facilitator protein NP_388809.1 1002501 D 224308 CDS NP_388810.2 255767217 939741 1003344..1004834 1 NC_000964.3 Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase 1004834 glpK 939741 glpK Bacillus subtilis subsp. subtilis str. 168 glycerol kinase NP_388810.2 1003344 D 224308 CDS NP_388811.2 255767218 936250 1004975..1006642 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10633102, 2127799, 8825777, 9595668; Product type e: enzyme; aerobic glycerol-3-phosphate dehydrogenase 1006642 glpD 936250 glpD Bacillus subtilis subsp. subtilis str. 168 aerobic glycerol-3-phosphate dehydrogenase NP_388811.2 1004975 D 224308 CDS NP_388812.2 255767219 936247 1006774..1008519 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15640167, 17662947; Product type e: enzyme; phosphoglucomutase 1008519 pgcA 936247 pgcA Bacillus subtilis subsp. subtilis str. 168 phosphoglucomutase NP_388812.2 1006774 D 224308 CDS NP_388813.1 16077997 939760 1008668..1009807 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type rc: receptor; sensor histidine kinase 1009807 yhcY 939760 yhcY Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_388813.1 1008668 D 224308 CDS NP_388814.1 16077998 939750 1009804..1010448 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16816187; Product type r: regulator; transcriptional regulator 1010448 yhcZ 939750 yhcZ Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_388814.1 1009804 D 224308 CDS NP_388815.1 16077999 936266 1010445..1010969 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15184374, 16816187; Product type e: enzyme; FMN-dependent NADPH-azoreductase 1010969 yhdA 936266 yhdA Bacillus subtilis subsp. subtilis str. 168 FMN-dependent NADPH-azoreductase NP_388815.1 1010445 D 224308 CDS NP_388816.1 16078000 939272 complement(1010984..1011226) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1011226 yhdB 939272 yhdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388816.1 1010984 R 224308 CDS NP_388817.1 16078001 936252 1011427..1011750 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1011750 yhdC 936252 yhdC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388817.1 1011427 D 224308 CDS NP_388818.2 255767220 939271 complement(1011792..1013258) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10206711, 14594841, 18761694, 18761696; Product type e: enzyme; peptidoglycan endopeptidase LytF 1013258 lytF 939271 lytF Bacillus subtilis subsp. subtilis str. 168 peptidoglycan endopeptidase LytF NP_388818.2 1011792 R 224308 CDS NP_388819.1 16078003 939744 complement(1013411..1013851) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16885456, 19006327; Product type r: regulator; Rrf2 family transcriptional regulator 1013851 nsrR 939744 nsrR Bacillus subtilis subsp. subtilis str. 168 Rrf2 family transcriptional regulator NP_388819.1 1013411 R 224308 CDS NP_388820.1 16078004 936263 complement(1013958..1015616) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1015616 ygxB 936263 ygxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388820.1 1013958 R 224308 CDS NP_388821.1 16078005 939747 1015647..1017053 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 8144469; Product type ph: phenotype; stage V sporulation protein R 1017053 spoVR 939747 spoVR Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein R NP_388821.1 1015647 D 224308 CDS NP_388822.2 255767221 936265 complement(1017083..1018468) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12897025, 8830275; Product type e: enzyme; alkaline phosphatase 1018468 phoA 936265 phoA Bacillus subtilis subsp. subtilis str. 168 alkaline phosphatase NP_388822.2 1017083 R 224308 CDS NP_388823.2 255767222 939269 1018998..1020002 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244, 16950129, 9457885; Product type e: enzyme; peptidoglycan endopeptidase LytE 1020002 lytE 939269 lytE Bacillus subtilis subsp. subtilis str. 168 peptidoglycan endopeptidase LytE NP_388823.2 1018998 D 224308 CDS NP_388824.2 255767223 939267 complement(1020073..1020948) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8045899; Product type r : regulator; LysR family transcriptional regulator 1020948 citR 939267 citR Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_388824.2 1020073 R 224308 CDS NP_388825.2 255767224 936270 1021057..1022157 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 4211224, 8045898, 8045899; Product type e: enzyme; citrate synthase 1022157 citA 936270 citA Bacillus subtilis subsp. subtilis str. 168 citrate synthase NP_388825.2 1021057 D 224308 CDS NP_388826.1 16078010 939749 1022231..1023100 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; oxidoreductase 1023100 yhdF 939749 yhdF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388826.1 1022231 D 224308 CDS NP_388827.1 16078011 939746 1023350..1024747 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16621821, 16850406; Product type t : transporter; amino acid permease 1024747 ctrA 939746 ctrA Bacillus subtilis subsp. subtilis str. 168 amino acid permease NP_388827.1 1023350 D 224308 CDS NP_388828.1 16078012 936264 1024865..1026220 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YhdH 1026220 yhdH 936264 yhdH Bacillus subtilis subsp. subtilis str. 168 sodium-dependent transporter YhdH NP_388828.1 1024865 D 224308 CDS NP_388829.1 16078013 939277 complement(1026255..1027664) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 1027664 yhdI 939277 yhdI Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388829.1 1026255 R 224308 CDS NP_388830.1 16078014 939275 1027774..1028202 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; N-acetyltransferase YhdJ 1028202 yhdJ 939275 yhdJ Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YhdJ NP_388830.1 1027774 D 224308 CDS NP_388831.1 16078015 936268 complement(1028233..1028523) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype; anti-sigma-M factor YhdK 1028523 yhdK 936268 yhdK Bacillus subtilis subsp. subtilis str. 168 anti-sigma-M factor YhdK NP_388831.1 1028233 R 224308 CDS NP_388832.1 16078016 939753 complement(1028511..1029587) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216858; Product type ph: phenotype; anti-sigma-M factor YhdL 1029587 yhdL 939753 yhdL Bacillus subtilis subsp. subtilis str. 168 anti-sigma-M factor YhdL NP_388832.1 1028511 R 224308 CDS NP_388833.1 16078017 936267 complement(1029577..1030068) 1 NC_000964.3 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis this protein is activated in response to cell wall antibiotics, ethanol, heat, acid, and superoxide stress; RNA polymerase sigma factor SigM 1030068 sigM 936267 sigM Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigM NP_388833.1 1029577 R 224308 CDS NP_388834.1 16078018 939270 1030265..1031260 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10220166, 15019785; Product type e: enzyme; general stress protein 69 1031260 yhdN 939270 yhdN Bacillus subtilis subsp. subtilis str. 168 general stress protein 69 NP_388834.1 1030265 D 224308 CDS NP_388835.1 16078019 936269 1031395..1031994 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 1557036, 17557823; Product type e: enzyme; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1031994 plsC 936269 plsC Bacillus subtilis subsp. subtilis str. 168 1-acyl-sn-glycerol-3-phosphate acyltransferase NP_388835.1 1031395 D 224308 CDS NP_388836.1 16078020 939280 complement(1032063..1033397) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pt : transporter; hypothetical protein 1033397 yhdP 939280 yhdP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388836.1 1032063 R 224308 CDS NP_388837.1 16078021 939283 complement(1033458..1033889) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14663075; Product type r: regulator; MerR family transcriptional regulator 1033889 cueR 939283 cueR Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_388837.1 1033458 R 224308 CDS NP_388838.1 16078022 939752 1034046..1035227 1 NC_000964.3 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 1035227 yhdR 939752 yhdR Bacillus subtilis subsp. subtilis str. 168 aspartate aminotransferase NP_388838.1 1034046 D 224308 CDS NP_388840.1 16078024 936275 1035554..1036939 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 1036939 yhdT 936275 yhdT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388840.1 1035554 D 224308 CDS NP_388841.1 16078025 939754 complement(1036953..1037309) 1 NC_000964.3 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; protein CrcB homolog 1 1037309 crcBA 939754 crcBA Bacillus subtilis subsp. subtilis str. 168 protein CrcB homolog 1 NP_388841.1 1036953 R 224308 CDS NP_388842.1 16078026 936272 complement(1037306..1037701) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12904550, 15849754, 16850406, 8844142; Product type f: factor; protein CrcB homolog 2 1037701 yhdV 936272 yhdV Bacillus subtilis subsp. subtilis str. 168 protein CrcB homolog 2 NP_388842.1 1037306 R 224308 CDS NP_388843.1 16078027 939751 complement(1037688..1038419) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8012593; Product type pe : enzyme; glycerophosphoryl diester phosphodiesterase 1038419 yhdW 939751 yhdW Bacillus subtilis subsp. subtilis str. 168 glycerophosphoryl diester phosphodiesterase NP_388843.1 1037688 R 224308 CDS NP_388844.1 16078028 939284 1038653..1038760 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1038760 yhdX 939284 yhdX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388844.1 1038653 D 224308 CDS NP_388845.1 16078029 939285 1038909..1040024 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12077558, 15849754, 16850406; Product type pm: membrane component; small mechanosensitive ion chanel protein MscS 1040024 yhdY 939285 yhdY Bacillus subtilis subsp. subtilis str. 168 small mechanosensitive ion chanel protein MscS NP_388845.1 1038909 D 224308 CDS NP_388846.1 16078030 936271 1040094..1040837 1 NC_000964.3 Modulates the activities of several enzymes which are inactive in their acetylated form; NAD-dependent protein deacetylase 1040837 yhdZ 936271 yhdZ Bacillus subtilis subsp. subtilis str. 168 NAD-dependent protein deacetylase NP_388846.1 1040094 D 224308 CDS NP_388847.1 16078031 936280 complement(1040861..1041709) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polysaccharide deacetylase 1041709 yheN 936280 yheN Bacillus subtilis subsp. subtilis str. 168 polysaccharide deacetylase NP_388847.1 1040861 R 224308 CDS NP_388848.1 16078032 939759 1041994..1042842 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17005988, 9003455; Product type e: enzyme; D-alanine aminotransferase 1042842 dat 939759 dat Bacillus subtilis subsp. subtilis str. 168 D-alanine aminotransferase NP_388848.1 1041994 D 224308 CDS NP_388849.1 16078033 936274 complement(1042885..1044246) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 11274110, 15849754, 16850406; Product type t: transporter; Na(+)/H(+) antiporter NhaC 1044246 nhaC 936274 nhaC Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter NhaC NP_388849.1 1042885 R 224308 CDS NP_388850.2 50812206 939286 complement(1044373..1044873) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 1198853, 16159758; Product type f : factor; stress response protein NhaX 1044873 nhaX 939286 nhaX Bacillus subtilis subsp. subtilis str. 168 stress response protein NhaX NP_388850.2 1044373 R 224308 CDS NP_388851.1 16078035 939757 1045037..1045198 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 1045198 yheJ 939757 yheJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388851.1 1045037 D 224308 CDS NP_388852.1 16078036 936278 1045318..1047075 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein YheI 1047075 yheI 936278 yheI Bacillus subtilis subsp. subtilis str. 168 multidrug resistance ABC transporter ATP-binding/permease protein YheI NP_388852.1 1045318 D 224308 CDS NP_388853.1 16078037 939287 1047072..1049093 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15855514, 16487324; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein YheH 1049093 yheH 939287 yheH Bacillus subtilis subsp. subtilis str. 168 multidrug resistance ABC transporter ATP-binding/permease protein YheH NP_388853.1 1047072 D 224308 CDS NP_388854.1 16078038 939755 complement(1049142..1049762) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1049762 yheG 939755 yheG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388854.1 1049142 R 224308 CDS NP_388855.1 16078039 936277 complement(1049801..1049926) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1049926 yheF 936277 yheF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388855.1 1049801 R 224308 CDS NP_388856.1 16078040 939281 complement(1050031..1050234) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 3009398, 9572981; Product type cp: cell process; small acid-soluble spore protein B 1050234 sspB 939281 sspB Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein B NP_388856.1 1050031 R 224308 CDS NP_388857.1 16078041 939756 complement(1050443..1050661) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1050661 yheE 939756 yheE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388857.1 1050443 R 224308 CDS NP_388858.2 255767225 936276 complement(1050811..1052172) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type f: factor; endospore coat-associated protein YheD 1052172 yheD 936276 yheD Bacillus subtilis subsp. subtilis str. 168 endospore coat-associated protein YheD NP_388858.2 1050811 R 224308 CDS NP_388859.1 16078043 939293 complement(1052162..1053253) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15231775; Product type f: factor; endospore coat-associated protein YheC 1053253 yheC 939293 yheC Bacillus subtilis subsp. subtilis str. 168 endospore coat-associated protein YheC NP_388859.1 1052162 R 224308 CDS NP_388860.1 16078044 939764 1053520..1054653 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16684363; hypothetical protein 1054653 yheB 939764 yheB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388860.1 1053520 D 224308 CDS NP_388861.1 16078045 936288 1054746..1055099 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1055099 yheA 936288 yheA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388861.1 1054746 D 224308 CDS NP_388862.1 16078046 939758 complement(1055143..1056216) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290; hypothetical protein 1056216 yhaZ 939758 yhaZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388862.1 1055143 R 224308 CDS NP_388864.2 50812207 939288 1056702..1057568 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pe : enzyme; hydrolase 1057568 yhaX 939288 yhaX Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_388864.2 1056702 D 224308 CDS NP_388865.1 16081159 937935 1057680..1059185 1 NC_000964.3 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; oxygen-independent coproporphyrinogen-III oxidase 1059185 hemZ 937935 hemZ Bacillus subtilis subsp. subtilis str. 168 oxygen-independent coproporphyrinogen-III oxidase NP_388865.1 1057680 D 224308 CDS NP_388866.2 255767226 939761 complement(1059203..1060420) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 14987767, 15849754, 15919996, 16850406; Product type t: transporter; K(+)/H(+) antiporter YhaU 1060420 yhaU 939761 yhaU Bacillus subtilis subsp. subtilis str. 168 K(+)/H(+) antiporter YhaU NP_388866.2 1059203 R 224308 CDS NP_388867.1 16078050 936284 complement(1060427..1060924) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type t: transporter; K(+)/H(+) antiporter subunit KhtT 1060924 khtT 936284 khtT Bacillus subtilis subsp. subtilis str. 168 K(+)/H(+) antiporter subunit KhtT NP_388867.1 1060427 R 224308 CDS NP_388868.1 16078051 939291 complement(1060988..1061326) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14987767, 17679694; Product type f: factor; hypothetical protein 1061326 khtS 939291 khtS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388868.1 1060988 R 224308 CDS NP_388869.3 255767227 939767 1061491..1062258 1 NC_000964.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase/isomerase YhaR 1062258 yhaR 939767 yhaR Bacillus subtilis subsp. subtilis str. 168 enoyl-CoA hydratase/isomerase YhaR NP_388869.3 1061491 D 224308 CDS YP_003097698.1 255767228 8303023 complement(1062279..1062464) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1062464 yhzD 8303023 yhzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097698.1 1062279 R 224308 CDS NP_388870.2 255767229 936283 1062591..1063487 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 9106203; Product type t: transporter; ABC transporter ATP-binding protein 1063487 natA 936283 natA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388870.2 1062591 D 224308 CDS NP_388871.2 255767230 939763 1063480..1064739 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10356997, 15849754, 16850406, 9106203; Product type t: transporter; hypothetical protein 1064739 natB 939763 natB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388871.2 1063480 D 224308 CDS NP_388872.1 16078055 936282 1064846..1066072 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; metallophosphoesterase 1066072 yhaO 936282 yhaO Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_388872.1 1064846 D 224308 CDS NP_388873.1 16078056 936294 1066077..1068968 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 1068968 yhaN 936294 yhaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388873.1 1066077 D 224308 CDS NP_388874.1 16078057 939762 1069042..1069986 1 NC_000964.3 catalyzes the exonucleic cleavage of mRNA yielding nucleioside 5'-phosphates; 3'-5' exoribonuclease YhaM 1069986 yhaM 939762 yhaM Bacillus subtilis subsp. subtilis str. 168 3'-5' exoribonuclease YhaM NP_388874.1 1069042 D 224308 CDS NP_388875.1 16078058 936285 1070111..1070323 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523133; Product type ph: phenotype; sporulation protein YhaL 1070323 yhaL 936285 yhaL Bacillus subtilis subsp. subtilis str. 168 sporulation protein YhaL NP_388875.1 1070111 D 224308 CDS NP_388876.1 16078059 939294 complement(1070364..1071242) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12634326, 12682299, 14976191, 16516208; Product type lp: lipoprotein; foldase protein PrsA 1071242 prsA 939294 prsA Bacillus subtilis subsp. subtilis str. 168 foldase protein PrsA NP_388876.1 1070364 R 224308 CDS YP_003097699.1 255767231 8303205 1071402..1071488 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1071488 yhzE 8303205 yhzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097699.1 1071402 D 224308 CDS NP_388878.2 255767232 936292 complement(1072042..1072560) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; membrane protein 1072560 yhaJ 936292 yhaJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388878.2 1072042 R 224308 CDS NP_388879.1 16078062 939295 1072768..1073109 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1073109 yhaI 939295 yhaI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388879.1 1072768 D 224308 CDS NP_388880.1 16078063 939765 complement(1073106..1073717) 1 NC_000964.3 hpr; ScoC; MarR family; protease production regulatory protein; MarR family transcriptional regulator 1073717 hpr 939765 hpr Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388880.1 1073106 R 224308 CDS NP_388881.1 16078064 936291 complement(1073895..1074251) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11429463; Product type pm : membrane component; membrane protein 1074251 yhaH 936291 yhaH Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388881.1 1073895 R 224308 CDS YP_003097700.1 255767233 8303073 1074381..1074572 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 1074572 yhzF 8303073 yhzF Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097700.1 1074381 D 224308 CDS NP_388882.2 255767234 936290 complement(1074646..1075164) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702295, 15849754, 16850406, 10735881; Product type t: transporter; tryptophan transport protein 1075164 trpP 936290 trpP Bacillus subtilis subsp. subtilis str. 168 tryptophan transport protein NP_388882.2 1074646 R 224308 CDS NP_388883.1 16078066 936304 complement(1075289..1076368) 1 NC_000964.3 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine; phosphoserine aminotransferase 1076368 serC 936304 serC Bacillus subtilis subsp. subtilis str. 168 phosphoserine aminotransferase NP_388883.1 1075289 R 224308 CDS NP_388884.1 16078067 939769 complement(1076515..1076952) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15703176, 16934294, 9579061; Product type e : enzyme; protein hit 1076952 hinT 939769 hinT Bacillus subtilis subsp. subtilis str. 168 protein hit NP_388884.1 1076515 R 224308 CDS NP_388885.1 16078068 936293 1077440..1078183 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 11807061, 8581172; Product type t: transporter; ABC transporter ATP-binding protein 1078183 ecsA 936293 ecsA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_388885.1 1077440 D 224308 CDS NP_388886.1 16078069 939298 1078176..1079402 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10027970, 15175311, 15849754, 16850406, 8581172; Product type t : transporter; ABC transporter permease EcsB 1079402 ecsB 939298 ecsB Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease EcsB NP_388886.1 1078176 D 224308 CDS NP_388887.1 16078070 939774 1079422..1080132 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10027970; Product type pe : enzyme; ABC transporter substrate-binding protein EcsC 1080132 ecsC 939774 ecsC Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein EcsC NP_388887.1 1079422 D 224308 CDS NP_388888.2 255767235 936299 complement(1080150..1081340) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amidohydrolase YhaA 1081340 yhaA 936299 yhaA Bacillus subtilis subsp. subtilis str. 168 amidohydrolase YhaA NP_388888.2 1080150 R 224308 CDS NP_388889.1 16078072 939301 complement(1081413..1082804) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 1082804 yhfA 939301 yhfA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388889.1 1081413 R 224308 CDS NP_388890.1 16078073 936298 complement(1082870..1083184) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1083184 yhgB 936298 yhgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388890.1 1082870 R 224308 CDS NP_388891.1 16078074 939297 complement(1083229..1083729) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1083729 yhgC 939297 yhgC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388891.1 1083229 R 224308 CDS NP_388892.2 255767236 939766 1083851..1085995 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11567005, 8335642; Product type e: enzyme; penicillin-binding protein 1F 1085995 pbpF 939766 pbpF Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 1F NP_388892.2 1083851 D 224308 CDS NP_388893.1 16078076 936296 1086117..1087178 1 NC_000964.3 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III; uroporphyrinogen decarboxylase 1087178 hemE 936296 hemE Bacillus subtilis subsp. subtilis str. 168 uroporphyrinogen decarboxylase NP_388893.1 1086117 D 224308 CDS NP_388894.1 16078077 939772 1087250..1088182 1 NC_000964.3 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 1088182 hemH 939772 hemH Bacillus subtilis subsp. subtilis str. 168 ferrochelatase NP_388894.1 1087250 D 224308 CDS NP_388895.1 16078078 936311 1088197..1089609 1 NC_000964.3 catalyzes the formation of protoporphyrin IX from protoporphyrinogen IX; protoporphyrinogen oxidase 1089609 hemY 936311 hemY Bacillus subtilis subsp. subtilis str. 168 protoporphyrinogen oxidase NP_388895.1 1088197 D 224308 CDS NP_388896.1 16078079 939305 1089755..1090330 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15944459; Product type pr : regulator; TetR family transcriptional regulator 1090330 yhgD 939305 yhgD Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_388896.1 1089755 D 224308 CDS NP_388897.1 16078080 936303 1090401..1092728 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor; hypothetical protein 1092728 yhgE 936303 yhgE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388897.1 1090401 D 224308 CDS NP_388898.1 16078081 939306 complement(1092770..1093747) 1 NC_000964.3 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis; 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 1093747 fabHB 939306 fabHB Bacillus subtilis subsp. subtilis str. 168 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 2 NP_388898.1 1092770 R 224308 CDS NP_388899.1 16078082 936308 1093874..1094650 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1094650 yhfC 936308 yhfC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388899.1 1093874 D 224308 CDS NP_388901.1 16078084 936306 1095063..1096103 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase YhfE 1096103 yhfE 936306 yhfE Bacillus subtilis subsp. subtilis str. 168 aminopeptidase YhfE NP_388901.1 1095063 D 224308 CDS NP_388902.1 16078085 939309 1096116..1096523 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1096523 yhfF 939309 yhfF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388902.1 1096116 D 224308 CDS NP_388903.1 16078086 939770 complement(1096560..1097849) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8634258; Product type t : transporter; proton/sodium-glutamate symport protein 1097849 gltT 939770 gltT Bacillus subtilis subsp. subtilis str. 168 proton/sodium-glutamate symport protein NP_388903.1 1096560 R 224308 CDS NP_388904.1 16078087 936305 complement(1098120..1098260) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 1098260 yhfH 936305 yhfH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388904.1 1098120 R 224308 CDS NP_388905.1 16078088 936318 1098412..1099146 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1099146 yhfI 936318 yhfI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388905.1 1098412 D 224308 CDS NP_388906.1 16078089 939310 1099159..1100154 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoate-protein ligase LplJ 1100154 yhfJ 939310 yhfJ Bacillus subtilis subsp. subtilis str. 168 lipoate-protein ligase LplJ NP_388906.1 1099159 D 224308 CDS NP_388907.1 16078090 936309 1100219..1100863 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11790741; Product type pe : enzyme; sugar epimerase YhfK 1100863 yhfK 936309 yhfK Bacillus subtilis subsp. subtilis str. 168 sugar epimerase YhfK NP_388907.1 1100219 D 224308 CDS NP_388908.2 255767237 939308 1100980..1102521 1 NC_000964.3 activates fatty acids by binding to coenzyme A; long-chain-fatty-acid--CoA ligase 1102521 yhfL 939308 yhfL Bacillus subtilis subsp. subtilis str. 168 long-chain-fatty-acid--CoA ligase NP_388908.2 1100980 D 224308 CDS NP_388909.1 16078092 936312 complement(1102560..1102955) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1102955 yhfM 936312 yhfM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388909.1 1102560 R 224308 CDS NP_388910.1 16078093 936314 1103104..1104384 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9015299; Product type pe : enzyme; metalloprotease YhfN 1104384 yhfN 936314 yhfN Bacillus subtilis subsp. subtilis str. 168 metalloprotease YhfN NP_388910.1 1103104 D 224308 CDS NP_388911.2 255767238 939313 complement(1104423..1105568) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 14688235, 15205417, 17666034, 3108260, 9811547; Product type e : enzyme; subtilisin E 1105568 aprE 939313 aprE Bacillus subtilis subsp. subtilis str. 168 subtilisin E NP_388911.2 1104423 R 224308 CDS NP_388912.1 16078095 939778 1106003..1106452 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YhfO 1106452 yhfO 939778 yhfO Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YhfO NP_388912.1 1106003 D 224308 CDS NP_388913.1 16078096 939312 1106524..1107516 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12057962, 9643546; Product type pe: enzyme; quinone oxidoreductase YhfP 1107516 yhfP 939312 yhfP Bacillus subtilis subsp. subtilis str. 168 quinone oxidoreductase YhfP NP_388913.1 1106524 D 224308 CDS NP_388914.2 255767239 936324 1107733..1108704 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pt : transporter; ABC transporter substrate-binding protein 1108704 yhfQ 936324 yhfQ Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein NP_388914.2 1107733 D 224308 CDS NP_388915.1 16078098 939773 complement(1108736..1109317) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10869096, 11827481, 17693564; Product type e: enzyme; phosphatase PhoE 1109317 phoE 939773 phoE Bacillus subtilis subsp. subtilis str. 168 phosphatase PhoE NP_388915.1 1108736 R 224308 CDS NP_388916.1 16078099 939311 complement(1109388..1110482) 1 NC_000964.3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 1110482 yhfS 939311 yhfS Bacillus subtilis subsp. subtilis str. 168 acetyl-CoA acetyltransferase NP_388916.1 1109388 R 224308 CDS NP_388917.1 16078100 936315 complement(1110479..1111918) 1 NC_000964.3 activates fatty acids by binding to coenzyme A; acyl--CoA ligase 1111918 yhfT 936315 yhfT Bacillus subtilis subsp. subtilis str. 168 acyl--CoA ligase NP_388917.1 1110479 R 224308 CDS NP_388918.1 16078101 939321 complement(1111925..1112485) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12368242, 15849754, 16850406; Product type t: transporter; biotin transporter BioY 1112485 bioY 939321 bioY Bacillus subtilis subsp. subtilis str. 168 biotin transporter BioY NP_388918.1 1111925 R 224308 CDS NP_388919.1 16078102 936320 complement(1112620..1113918) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11481493, 12657801, 12962628, 15033535, 16819829, 17003124; Product type rc : receptor; heme-based aerotactic transducer HemAT 1113918 hemAT 936320 hemAT Bacillus subtilis subsp. subtilis str. 168 heme-based aerotactic transducer HemAT NP_388919.1 1112620 R 224308 CDS NP_388920.1 16078103 936319 complement(1114057..1115586) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; rieske 2Fe-2S iron-sulfur protein YhfW 1115586 yhfW 936319 yhfW Bacillus subtilis subsp. subtilis str. 168 rieske 2Fe-2S iron-sulfur protein YhfW NP_388920.1 1114057 R 224308 CDS NP_388921.1 16078104 939316 1115698..1116555 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1116555 yhxC 939316 yhxC Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388921.1 1115698 D 224308 CDS NP_388922.1 16078105 939319 complement(1116583..1116816) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1116816 yhzC 939319 yhzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388922.1 1116583 R 224308 CDS NP_388923.1 16078106 936338 1117109..1117687 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619, 16554821, 16907804, 17468244; Product type r: regulator; competence transcription factor 1117687 comK 936338 comK Bacillus subtilis subsp. subtilis str. 168 competence transcription factor NP_388923.1 1117109 D 224308 CDS NP_388924.1 16078107 939776 complement(1117734..1118633) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1118633 yhxD 939776 yhxD Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388924.1 1117734 R 224308 CDS NP_388925.1 16078108 936321 1118850..1119119 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1119119 yhjA 936321 yhjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388925.1 1118850 D 224308 CDS NP_388926.1 16078109 939317 complement(1119162..1120631) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16267290, 16850406; Product type pt: transporter; symporter 1120631 yhjB 939317 yhjB Bacillus subtilis subsp. subtilis str. 168 symporter NP_388926.1 1119162 R 224308 CDS NP_388927.1 16078110 939777 complement(1120628..1120828) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pf : factor; membrane protein 1120828 yhjC 939777 yhjC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388927.1 1120628 R 224308 CDS NP_388928.1 16078111 936334 complement(1121036..1121398) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16267290; hypothetical protein 1121398 yhjD 936334 yhjD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388928.1 1121036 R 224308 CDS NP_388929.1 16078112 936333 1121550..1122173 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1122173 yhjE 936333 yhjE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_388929.1 1121550 D 224308 CDS NP_388930.1 16078113 939318 1122175..1122681 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11309398, 14568161, 9325333; Product type e: enzyme; signal peptidase I V 1122681 sipV 939318 sipV Bacillus subtilis subsp. subtilis str. 168 signal peptidase I V NP_388930.1 1122175 D 224308 CDS NP_388931.1 16078114 936325 1122862..1124361 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15121720, 7678243; Product type pe: enzyme; aromatic compound monooxygenase YhjG 1124361 yhjG 936325 yhjG Bacillus subtilis subsp. subtilis str. 168 aromatic compound monooxygenase YhjG NP_388931.1 1122862 D 224308 CDS NP_388932.1 16078115 939329 1124438..1124965 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 1124965 yhjH 939329 yhjH Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_388932.1 1124438 D 224308 CDS NP_388933.1 16078116 936346 complement(1125123..1126328) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17056753; Product type t: transporter; sugar transporter 1126328 glcP 936346 glcP Bacillus subtilis subsp. subtilis str. 168 sugar transporter NP_388933.1 1125123 R 224308 CDS NP_388934.2 255767240 936337 complement(1126400..1127452) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon putative oxidoreductase NtdC 1127452 ntdC 936337 ntdC Bacillus subtilis subsp. subtilis str. 168 NTD biosynthesis operon putative oxidoreductase NtdC NP_388934.2 1126400 R 224308 CDS NP_388935.2 255767241 939323 complement(1127466..1128314) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon putative hydrolase NtdB 1128314 ntdB 939323 ntdB Bacillus subtilis subsp. subtilis str. 168 NTD biosynthesis operon putative hydrolase NtdB NP_388935.2 1127466 R 224308 CDS NP_388936.1 16078119 939788 complement(1128286..1129611) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612444, 17056753; Product type e: enzyme; NTD biosynthesis operon protein NtdA 1129611 ntdA 939788 ntdA Bacillus subtilis subsp. subtilis str. 168 NTD biosynthesis operon protein NtdA NP_388936.1 1128286 R 224308 CDS NP_388937.1 16078120 936344 1129715..1130704 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056753; Product type r: regulator; NTD biosynthesis operon regulator NtdR 1130704 yhjM 936344 yhjM Bacillus subtilis subsp. subtilis str. 168 NTD biosynthesis operon regulator NtdR NP_388937.1 1129715 D 224308 CDS NP_388938.1 16078121 939324 complement(1130918..1132072) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1132072 yhjN 939324 yhjN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388938.1 1130918 R 224308 CDS NP_388939.1 16078122 939780 complement(1132179..1133384) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 1133384 yhjO 939780 yhjO Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388939.1 1132179 R 224308 CDS NP_388940.1 16078123 936342 1133498..1135225 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1135225 yhjP 936342 yhjP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388940.1 1133498 D 224308 CDS NP_388941.1 16078124 939779 complement(1135255..1135581) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier; cysteine-rich protein YhjQ 1135581 yhjQ 939779 yhjQ Bacillus subtilis subsp. subtilis str. 168 cysteine-rich protein YhjQ NP_388941.1 1135255 R 224308 CDS NP_388942.1 16078125 939352 complement(1135699..1136136) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pc: carrier; hypothetical protein 1136136 yhjR 939352 yhjR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388942.1 1135699 R 224308 CDS NP_388943.2 255767242 936341 1136320..1139820 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme; ATP-dependent helicase/deoxyribonuclease subunit B 1139820 addB 936341 addB Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase/deoxyribonuclease subunit B NP_388943.2 1136320 D 224308 CDS NP_388944.2 255767243 939793 1139807..1143505 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244, 16385024, 16780573, 7746142, 8387145, 8510642, 8752323; Product type e: enzyme; ATP-dependent helicase/nuclease subunit A 1143505 addA 939793 addA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase/nuclease subunit A NP_388944.2 1139807 D 224308 CDS NP_388945.3 255767244 936351 1143577..1144752 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573, 7968921, 8493111; Product type e: enzyme; nuclease SbcCD subunit D 1144752 sbcD 936351 sbcD Bacillus subtilis subsp. subtilis str. 168 nuclease SbcCD subunit D NP_388945.3 1143577 D 224308 CDS NP_388946.2 255767245 939784 1144749..1148141 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16780573; Product type e: enzyme; nuclease SbcCD subunit C 1148141 sbcC 939784 sbcC Bacillus subtilis subsp. subtilis str. 168 nuclease SbcCD subunit C NP_388946.2 1144749 D 224308 CDS NP_388947.1 16078130 936345 1148155..1148457 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16780573; Product type pe : enzyme; hypothetical protein 1148457 yisB 936345 yisB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388947.1 1148155 D 224308 CDS NP_388948.1 16078131 939326 complement(1148494..1148721) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein 1148721 gerPF 939326 gerPF Bacillus subtilis subsp. subtilis str. 168 spore germination protein NP_388948.1 1148494 R 224308 CDS NP_388949.1 16078132 939782 complement(1148744..1149145) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPE 1149145 gerPE 939782 gerPE Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerPE NP_388949.1 1148744 R 224308 CDS NP_388950.1 16078133 936349 complement(1149145..1149321) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPD 1149321 gerPD 936349 gerPD Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerPD NP_388950.1 1149145 R 224308 CDS NP_388951.1 16078134 939327 complement(1149318..1149935) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPC 1149935 gerPC 939327 gerPC Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerPC NP_388951.1 1149318 R 224308 CDS NP_388952.1 16078135 939781 complement(1149958..1150200) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein 1150200 gerPB 939781 gerPB Bacillus subtilis subsp. subtilis str. 168 spore germination protein NP_388952.1 1149958 R 224308 CDS NP_388953.1 16078136 936348 complement(1150206..1150427) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10715007; Product type cp: cell process; spore germination protein GerPA 1150427 gerPA 936348 gerPA Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerPA NP_388953.1 1150206 R 224308 CDS NP_388954.1 16078137 936347 complement(1150850..1151020) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme; aspartyl-phosphate phosphatase YisI 1151020 yisI 936347 yisI Bacillus subtilis subsp. subtilis str. 168 aspartyl-phosphate phosphatase YisI NP_388954.1 1150850 R 224308 CDS NP_388955.1 16078138 939786 complement(1151166..1152089) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process; inner spore coat protein H-like protein 1152089 yisJ 939786 yisJ Bacillus subtilis subsp. subtilis str. 168 inner spore coat protein H-like protein NP_388955.1 1151166 R 224308 CDS NP_388956.1 16078139 936356 1152244..1153149 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1153149 yisK 936356 yisK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388956.1 1152244 D 224308 CDS NP_388957.1 16078140 939333 1153265..1153621 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1153621 yisL 939333 yisL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388957.1 1153265 D 224308 CDS NP_388958.1 16078141 936350 1153789..1156473 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10336490, 15205417, 17269748, 9004506, 9675284; Product type e: enzyme; cell wall-associated protease 1156473 wprA 936350 wprA Bacillus subtilis subsp. subtilis str. 168 cell wall-associated protease NP_388958.1 1153789 D 224308 CDS NP_388959.1 16078142 936354 complement(1156504..1157091) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1157091 yisN 936354 yisN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388959.1 1156504 R 224308 CDS NP_388960.2 50812210 939783 1157237..1159081 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme; asparagine synthetase 3 1159081 asnO 939783 asnO Bacillus subtilis subsp. subtilis str. 168 asparagine synthetase 3 NP_388960.2 1157237 D 224308 CDS YP_054576.1 50812211 2914284 complement(1159211..1159690) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1159690 yizA 2914284 yizA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054576.1 1159211 R 224308 CDS NP_388961.1 16078144 936353 1159922..1160746 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; squalene/phytoene synthase 1160746 yisP 936353 yisP Bacillus subtilis subsp. subtilis str. 168 squalene/phytoene synthase NP_388961.1 1159922 D 224308 CDS NP_388962.1 16078145 939335 complement(1160776..1162143) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 1162143 yisQ 939335 yisQ Bacillus subtilis subsp. subtilis str. 168 transporter NP_388962.1 1160776 R 224308 CDS NP_388963.1 16078146 936352 1162267..1163130 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 1163130 yisR 936352 yisR Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_388963.1 1162267 D 224308 CDS NP_388964.1 16078147 936363 1163148..1164161 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8407808; Product type r : regulator; LacI family transcriptional regulator 1164161 degA 936363 degA Bacillus subtilis subsp. subtilis str. 168 LacI family transcriptional regulator NP_388964.1 1163148 D 224308 CDS NP_388965.1 16078148 939785 1164370..1165398 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pe : enzyme; oxidoreductase 1165398 yisS 939785 yisS Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_388965.1 1164370 D 224308 CDS NP_388966.2 50812212 936355 complement(1165449..1165958) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1165958 yisT 936355 yisT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388966.2 1165449 R 224308 CDS NP_388967.1 16078150 939338 complement(1166008..1166670) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid transporter YisU 1166670 yisU 939338 yisU Bacillus subtilis subsp. subtilis str. 168 amino acid transporter YisU NP_388967.1 1166008 R 224308 CDS NP_388968.2 50812213 936360 1166737..1168191 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15223311; Product type pr : regulator; GntR family transcriptional regulator 1168191 yisV 936360 yisV Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_388968.2 1166737 D 224308 CDS NP_388970.1 16078153 939343 complement(1168199..1168837) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1168837 yisX 939343 yisX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388970.1 1168199 R 224308 CDS NP_388971.1 16078154 939790 1169043..1169849 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YisY 1169849 yisY 939790 yisY Bacillus subtilis subsp. subtilis str. 168 AB hydrolase superfamily protein YisY NP_388971.1 1169043 D 224308 CDS NP_388972.1 16078155 936359 complement(1169877..1170476) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme; adenylyl-sulfate kinase 1170476 yisZ 936359 yisZ Bacillus subtilis subsp. subtilis str. 168 adenylyl-sulfate kinase NP_388972.1 1169877 R 224308 CDS NP_388973.2 50812214 939334 complement(1170473..1171642) 1 NC_000964.3 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; sulfate adenylyltransferase 1171642 sat 939334 sat Bacillus subtilis subsp. subtilis str. 168 sulfate adenylyltransferase NP_388973.2 1170473 R 224308 CDS NP_388974.2 50812215 939787 complement(1171755..1172465) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836; Product type pe : enzyme; phosphoadenosine phosphosulfate reductase 1172465 yitB 939787 yitB Bacillus subtilis subsp. subtilis str. 168 phosphoadenosine phosphosulfate reductase NP_388974.2 1171755 R 224308 CDS NP_388975.1 16078158 936357 1172650..1173336 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme; 2-phosphosulfolactate phosphatase 1173336 yitC 936357 yitC Bacillus subtilis subsp. subtilis str. 168 2-phosphosulfolactate phosphatase NP_388975.1 1172650 D 224308 CDS NP_388976.1 16078159 939794 1173333..1174091 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15383836; Product type e: enzyme; phosphosulfolactate synthase 1174091 yitD 939794 yitD Bacillus subtilis subsp. subtilis str. 168 phosphosulfolactate synthase NP_388976.1 1173333 D 224308 CDS NP_388977.1 16078160 936377 complement(1174136..1174765) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1174765 yitE 936377 yitE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388977.1 1174136 R 224308 CDS NP_388978.1 16078161 939345 complement(1174861..1175976) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 11747447; Product type pe: enzyme; isomerase 1175976 yitF 939345 yitF Bacillus subtilis subsp. subtilis str. 168 isomerase NP_388978.1 1174861 R 224308 CDS NP_388979.1 16078162 939791 complement(1175985..1177253) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15109717, 15849754, 16850406; Product type pt: transporter; MFS transporter 1177253 yitG 939791 yitG Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_388979.1 1175985 R 224308 CDS NP_388980.1 16078163 936361 complement(1177365..1178213) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YitH 1178213 yitH 936361 yitH Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YitH NP_388980.1 1177365 R 224308 CDS NP_388981.1 16078164 939344 complement(1178218..1178682) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase 1178682 yitI 939344 yitI Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase NP_388981.1 1178218 R 224308 CDS NP_388982.1 16078165 939796 complement(1178757..1180595) 1 NC_000964.3 catalyzes the formation of 5,10-methylenetetrahydrofolate from 5-methyltetrahydrofolate and S-adenosyl-L-homocysteine and methionine from S-adenosyl-L-methionine and L-homocysteine; expressed in B. subtilis under methionine starvation conditions; bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase 1180595 yitJ 939796 yitJ Bacillus subtilis subsp. subtilis str. 168 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase NP_388982.1 1178757 R 224308 CDS NP_388983.1 16078166 936375 complement(1180909..1181400) 1 NC_000964.3 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription; hypothetical protein 1181400 yitK 936375 yitK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388983.1 1180909 R 224308 CDS NP_388984.1 16078167 939792 1181499..1182395 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 1182395 yitL 939792 yitL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388984.1 1181499 D 224308 CDS NP_388985.1 16078168 936374 complement(1182448..1183032) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1183032 yitM 936374 yitM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388985.1 1182448 R 224308 CDS NP_388987.2 255767246 936373 complement(1183029..1183958) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1183958 yitO 936373 yitO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388987.2 1183029 R 224308 CDS NP_388988.1 16078171 939348 complement(1183943..1184479) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 6289325; hypothetical protein 1184479 yitP 939348 yitP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388988.1 1183943 R 224308 CDS YP_003097701.1 255767247 8302950 1184657..1185004 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein YizB 1185004 yizB 8302950 yizB Bacillus subtilis subsp. subtilis str. 168 DNA-binding protein YizB YP_003097701.1 1184657 D 224308 CDS NP_388989.2 255767248 939797 1185001..1185588 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1185588 yitQ 939797 yitQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388989.2 1185001 D 224308 CDS NP_388990.1 16078173 939798 1185608..1185901 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1185901 yitR 939798 yitR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388990.1 1185608 D 224308 CDS NP_388991.1 16078174 936384 1186037..1187653 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16672610, 1917867; Product type e: enzyme; neutral protease B 1187653 nprB 936384 nprB Bacillus subtilis subsp. subtilis str. 168 neutral protease B NP_388991.1 1186037 D 224308 CDS NP_388992.1 16078175 936376 complement(1187700..1188551) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; Degv domain-containing protein YitS 1188551 yitS 936376 yitS Bacillus subtilis subsp. subtilis str. 168 Degv domain-containing protein YitS NP_388992.1 1187700 R 224308 CDS NP_388993.1 16078176 939346 1188689..1189531 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1189531 yitT 939346 yitT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_388993.1 1188689 D 224308 CDS NP_388994.1 16078177 936380 1189646..1190005 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226659; Product type f : factor; intracellular proteinase inhibitor 1190005 ipi 936380 ipi Bacillus subtilis subsp. subtilis str. 168 intracellular proteinase inhibitor NP_388994.1 1189646 D 224308 CDS YP_003097702.1 255767249 8303093 complement(1190036..1190233) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1190233 yizC 8303093 yizC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097702.1 1190036 R 224308 CDS NP_388995.1 16078178 939795 complement(1190490..1191302) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YitU 1191302 yitU 939795 yitU Bacillus subtilis subsp. subtilis str. 168 phosphatase YitU NP_388995.1 1190490 R 224308 CDS NP_388996.1 16078179 939350 1191423..1192190 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; esterase YitV 1192190 yitV 939350 yitV Bacillus subtilis subsp. subtilis str. 168 esterase YitV NP_388996.1 1191423 D 224308 CDS NP_388997.1 16078180 936378 1192254..1192562 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; mip18 family protein YitW 1192562 yitW 936378 yitW Bacillus subtilis subsp. subtilis str. 168 mip18 family protein YitW NP_388997.1 1192254 D 224308 CDS NP_388999.3 255767250 939799 1192858..1194288 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16956367; Product type pe: enzyme; FAD-linked oxidoreductase YitY 1194288 yitY 939799 yitY Bacillus subtilis subsp. subtilis str. 168 FAD-linked oxidoreductase YitY NP_388999.3 1192858 D 224308 CDS NP_389000.1 16078183 939355 1194333..1194827 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; MFS transporter 1194827 yitZ 939355 yitZ Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_389000.1 1194333 D 224308 CDS NP_389001.2 255767251 936389 1195034..1196071 1 NC_000964.3 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate; N-acetyl-gamma-glutamyl-phosphate reductase 1196071 argC 936389 argC Bacillus subtilis subsp. subtilis str. 168 N-acetyl-gamma-glutamyl-phosphate reductase NP_389001.2 1195034 D 224308 CDS NP_389002.2 255767252 939800 1196091..1197311 1 NC_000964.3 bifunctional arginine biosynthesis protein ArgJ; functions at the 1st and 5th steps in arginine biosynthesis; involved in synthesis of acetylglutamate from glutamate and acetyl-CoA and ornithine by transacetylation between acetylornithine and glutmate; arginine biosynthesis bifunctional protein ArgJ 1197311 argJ 939800 argJ Bacillus subtilis subsp. subtilis str. 168 arginine biosynthesis bifunctional protein ArgJ NP_389002.2 1196091 D 224308 CDS NP_389003.1 16078186 936381 1197326..1198102 1 NC_000964.3 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 1198102 argB 936381 argB Bacillus subtilis subsp. subtilis str. 168 acetylglutamate kinase NP_389003.1 1197326 D 224308 CDS NP_389004.2 255767253 939357 1198099..1199256 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17012789; Product type e: enzyme; acetylornithine aminotransferase 1199256 argD 939357 argD Bacillus subtilis subsp. subtilis str. 168 acetylornithine aminotransferase NP_389004.2 1198099 D 224308 CDS NP_389005.2 255767254 936387 1199327..1200388 1 NC_000964.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl-phosphate synthase arginine-specific small chain 1200388 carA 936387 carA Bacillus subtilis subsp. subtilis str. 168 carbamoyl-phosphate synthase arginine-specific small chain NP_389005.2 1199327 D 224308 CDS NP_389006.3 255767255 939353 1200381..1203473 1 NC_000964.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl-phosphate synthase arginine-specific large chain 1203473 carB 939353 carB Bacillus subtilis subsp. subtilis str. 168 carbamoyl-phosphate synthase arginine-specific large chain NP_389006.3 1200381 D 224308 CDS NP_389007.1 16078190 936386 1203461..1204420 1 NC_000964.3 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; ornithine carbamoyltransferase 1204420 argF 936386 argF Bacillus subtilis subsp. subtilis str. 168 ornithine carbamoyltransferase NP_389007.1 1203461 D 224308 CDS NP_389008.1 16078191 936385 1204506..1204685 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1204685 yjzC 936385 yjzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389008.1 1204506 D 224308 CDS NP_389009.1 16078192 939364 complement(1204731..1204916) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1204916 yjzD 939364 yjzD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389009.1 1204731 R 224308 CDS NP_389010.1 16078193 936395 1205165..1205899 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1205899 yjaU 936395 yjaU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389010.1 1205165 D 224308 CDS NP_389011.2 255767256 939802 1205981..1206538 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523133; Product type pe : enzyme; hypothetical protein 1206538 yjaV 939802 yjaV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389011.2 1205981 D 224308 CDS NP_389012.2 50812218 936388 1206629..1207582 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1203607; Product type lp: lipoprotein; transcriptional activator protein med 1207582 med 936388 med Bacillus subtilis subsp. subtilis str. 168 transcriptional activator protein med NP_389012.2 1206629 D 224308 CDS NP_389013.1 16078196 939358 1207597..1207788 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10940045; Product type pf : factor; ComG operon repressor 1207788 comZ 939358 comZ Bacillus subtilis subsp. subtilis str. 168 ComG operon repressor NP_389013.1 1207597 D 224308 CDS NP_389014.1 16078197 939366 complement(1207818..1208057) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16391061; hypothetical protein 1208057 yjzB 939366 yjzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389014.1 1207818 R 224308 CDS NP_389015.1 16078198 936392 1208222..1209160 1 NC_000964.3 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1 1209160 fabHA 936392 fabHA Bacillus subtilis subsp. subtilis str. 168 3-oxoacyl-[acyl-carrier-protein] synthase 3 protein 1 NP_389015.1 1208222 D 224308 CDS NP_389016.1 16078199 939803 1209183..1210424 1 NC_000964.3 FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-[acyl-carrier-protein] synthase 2 1210424 fabF 939803 fabF Bacillus subtilis subsp. subtilis str. 168 3-oxoacyl-[acyl-carrier-protein] synthase 2 NP_389016.1 1209183 D 224308 CDS NP_389017.1 16078200 939806 1210500..1211285 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1211285 yjaZ 939806 yjaZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389017.1 1210500 D 224308 CDS NP_389018.1 16078201 936391 1211477..1212463 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter; oligopeptide transport ATP-binding protein AppD 1212463 appD 936391 appD Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport ATP-binding protein AppD NP_389018.1 1211477 D 224308 CDS NP_389019.2 255767257 936390 1212460..1213449 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7997159; Product type t : transporter; oligopeptide transport ATP-binding protein AppF 1213449 appF 936390 appF Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport ATP-binding protein AppF NP_389019.2 1212460 D 224308 CDS NP_389021.2 255767258 936400 1215243..1216193 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter; oligopeptide transport system permease protein AppB 1216193 appB 936400 appB Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport system permease protein AppB NP_389021.2 1215243 D 224308 CDS NP_389022.1 16078205 936394 1216210..1217121 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7997159; Product type t: transporter; oligopeptide transport system permease protein AppC 1217121 appC 936394 appC Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport system permease protein AppC NP_389022.1 1216210 D 224308 CDS NP_389023.1 16078206 939369 1217326..1218078 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1218078 yjbA 939369 yjbA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389023.1 1217326 D 224308 CDS NP_389024.1 16078207 939361 complement(1218113..1219105) 1 NC_000964.3 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophan--tRNA ligase 1219105 trpS 939361 trpS Bacillus subtilis subsp. subtilis str. 168 tryptophan--tRNA ligase NP_389024.1 1218113 R 224308 CDS NP_389025.1 16078208 936398 1219849..1221486 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11083832, 11401703, 12823818, 1901616; Product type lp: lipoprotein; oligopeptide ABC transporter binding lipoprotein 1221486 oppA 936398 oppA Bacillus subtilis subsp. subtilis str. 168 oligopeptide ABC transporter binding lipoprotein NP_389025.1 1219849 D 224308 CDS NP_389026.1 16078209 936397 1221594..1222529 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter; oligopeptide transport system permease protein OppB 1222529 oppB 936397 oppB Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport system permease protein OppB NP_389026.1 1221594 D 224308 CDS NP_389027.1 16078210 936396 1222533..1223450 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 15849754, 16850406, 1901616; Product type t: transporter; oligopeptide transport system permease protein OppC 1223450 oppC 936396 oppC Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport system permease protein OppC NP_389027.1 1222533 D 224308 CDS NP_389028.1 16078211 939814 1223455..1224531 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter; oligopeptide transport ATP-binding protein OppD 1224531 oppD 939814 oppD Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport ATP-binding protein OppD NP_389028.1 1223455 D 224308 CDS NP_389029.1 16078212 936410 1224533..1225450 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11401703, 1901616; Product type t: transporter; oligopeptide transport ATP-binding protein OppF 1225450 oppF 936410 oppF Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport ATP-binding protein OppF NP_389029.1 1224533 D 224308 CDS NP_389030.2 50812219 936399 1225557..1226774 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 1226774 yjbB 936399 yjbB Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_389030.2 1225557 D 224308 CDS NP_389031.2 255767259 939373 1226938..1227516 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17158660, 17158663; Product type pe: enzyme; acetyltransferase YjbC 1227516 yjbC 939373 yjbC Bacillus subtilis subsp. subtilis str. 168 acetyltransferase YjbC NP_389031.2 1226938 D 224308 CDS NP_389032.1 16078215 936407 1227697..1228092 1 NC_000964.3 the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; regulatory protein spx 1228092 spxA 936407 spxA Bacillus subtilis subsp. subtilis str. 168 regulatory protein spx NP_389032.1 1227697 D 224308 CDS NP_389033.1 16078216 939805 complement(1228135..1228791) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 1228791 yjbE 939805 yjbE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389033.1 1228135 R 224308 CDS NP_389034.1 16078217 936406 1229068..1229724 1 NC_000964.3 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adapter protein MecA 1 1229724 mecA 936406 mecA Bacillus subtilis subsp. subtilis str. 168 adapter protein MecA 1 NP_389034.1 1229068 D 224308 CDS NP_389035.1 16078218 939370 1229915..1231036 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17630974; Product type s: structure; competence protein CoiA 1231036 coiA 939370 coiA Bacillus subtilis subsp. subtilis str. 168 competence protein CoiA NP_389035.1 1229915 D 224308 CDS NP_389036.2 255767260 936404 1231083..1233095 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11741842; Product type e: enzyme; oligoendopeptidase F homolog 1233095 pepF 936404 pepF Bacillus subtilis subsp. subtilis str. 168 oligoendopeptidase F homolog NP_389036.2 1231083 D 224308 CDS YP_003097703.1 255767261 8303008 complement(1233133..1233300) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1233300 yizD 8303008 yizD Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097703.1 1233133 R 224308 CDS NP_389037.2 255767262 939365 complement(1233614..1234513) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17293416, 17908206; Product type pe: enzyme; hypothetical protein 1234513 yjbH 939365 yjbH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389037.2 1233614 R 224308 CDS NP_389038.1 16078221 936416 complement(1234510..1234908) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15866723, 17293416; Product type pe: enzyme; group 2 truncated hemoglobin YjbI 1234908 yjbI 936416 yjbI Bacillus subtilis subsp. subtilis str. 168 group 2 truncated hemoglobin YjbI NP_389038.1 1234510 R 224308 CDS NP_389039.1 16078222 939382 complement(1235163..1235708) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; murein lytic transglycosylase YjbJ 1235708 yjbJ 939382 yjbJ Bacillus subtilis subsp. subtilis str. 168 murein lytic transglycosylase YjbJ NP_389039.1 1235163 R 224308 CDS NP_389040.1 16078223 936408 complement(1235912..1236484) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456267, 16905149, 9642185; Product type pe: enzyme; hypothetical protein 1236484 yjbK 936408 yjbK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389040.1 1235912 R 224308 CDS NP_389041.1 16078224 939376 1236609..1236977 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1236977 yjbL 939376 yjbL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389041.1 1236609 D 224308 CDS NP_389042.1 16078225 939809 1237006..1237641 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18067544; Product type e: enzyme; GTP pyrophosphokinase YjbM 1237641 yjbM 939809 yjbM Bacillus subtilis subsp. subtilis str. 168 GTP pyrophosphokinase YjbM NP_389042.1 1237006 D 224308 CDS NP_389043.1 16078226 936414 1237660..1238460 1 NC_000964.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 1 1238460 ppnK 936414 ppnK Bacillus subtilis subsp. subtilis str. 168 inorganic polyphosphate/ATP-NAD kinase 1 NP_389043.1 1237660 D 224308 CDS NP_389044.1 16078227 939808 1238523..1239374 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; RNA pseudouridine synthase YjbO 1239374 yjbO 939808 yjbO Bacillus subtilis subsp. subtilis str. 168 RNA pseudouridine synthase YjbO NP_389044.1 1238523 D 224308 CDS NP_389045.1 16078228 936412 complement(1239387..1240121) 1 NC_000964.3 asymmetrical; catalyzes the formation of NTP and NMP from P(1),P(4)-bis(5'-nucleosyl) tetraphosphate; acts on bis(5'-guanosyl) tetraphosphate, bis(5'-xanthosyl)-tetraphosphate, on bis(5'-adenosyl)-tetraphosphate, and bis(5'-uridyl)-tetraphosphate; Bis(5'-nucleosyl)-tetraphosphatase PrpE 1240121 yjbP 936412 yjbP Bacillus subtilis subsp. subtilis str. 168 Bis(5'-nucleosyl)-tetraphosphatase PrpE NP_389045.1 1239387 R 224308 CDS NP_389046.1 16078229 939371 1240356..1242200 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; Na(+)/H(+) antiporter YjbQ 1242200 yjbQ 939371 yjbQ Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter YjbQ NP_389046.1 1240356 D 224308 CDS NP_389047.1 16078230 939807 1242449..1243159 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15709744, 15858269, 16356850, 17618314, 18054064; Product type e: enzyme; thiaminase 1243159 tenA 939807 tenA Bacillus subtilis subsp. subtilis str. 168 thiaminase NP_389047.1 1242449 D 224308 CDS NP_389048.1 16078231 936411 1243134..1243751 1 NC_000964.3 regulates the production of extracellular enzymes; regulatory protein TenI 1243751 tenI 936411 tenI Bacillus subtilis subsp. subtilis str. 168 regulatory protein TenI NP_389048.1 1243134 D 224308 CDS NP_389049.1 16078232 939377 1243735..1244844 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12627963, 15105420, 9827558; Product type e: enzyme; glycine oxidase 1244844 thiO 939377 thiO Bacillus subtilis subsp. subtilis str. 168 glycine oxidase NP_389049.1 1243735 D 224308 CDS NP_389050.1 16078233 939811 1244844..1245044 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 14567704, 14757766, 15489164; Product type c: carrier; sulfur carrier protein ThiS 1245044 thiS 939811 thiS Bacillus subtilis subsp. subtilis str. 168 sulfur carrier protein ThiS NP_389050.1 1244844 D 224308 CDS NP_389051.1 16078234 936422 1245041..1245811 1 NC_000964.3 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 1245811 thiG 936422 thiG Bacillus subtilis subsp. subtilis str. 168 thiazole synthase NP_389051.1 1245041 D 224308 CDS NP_389052.1 16078235 939816 1245808..1246818 1 NC_000964.3 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; sulfur carrier protein ThiS adenylyltransferase 1246818 thiF 939816 thiF Bacillus subtilis subsp. subtilis str. 168 sulfur carrier protein ThiS adenylyltransferase NP_389052.1 1245808 D 224308 CDS NP_389053.1 16078236 936415 1246837..1247652 1 NC_000964.3 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 1247652 yjbV 936415 yjbV Bacillus subtilis subsp. subtilis str. 168 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase NP_389053.1 1246837 D 224308 CDS NP_389054.2 50812220 939379 1247788..1248564 1 NC_000964.3 Catalyzes a key regulatory step in fatty acid biosynthesis; enoyl-ACP reductase 1248564 fabI 939379 fabI Bacillus subtilis subsp. subtilis str. 168 enoyl-ACP reductase NP_389054.2 1247788 D 224308 CDS NP_389055.1 16078238 939810 1248665..1249348 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process; spore coat protein O 1249348 cotO 939810 cotO Bacillus subtilis subsp. subtilis str. 168 spore coat protein O NP_389055.1 1248665 D 224308 CDS NP_389056.1 16078239 936418 complement(1249442..1249888) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process; spore coat protein Z 1249888 cotZ 936418 cotZ Bacillus subtilis subsp. subtilis str. 168 spore coat protein Z NP_389056.1 1249442 R 224308 CDS NP_389057.1 16078240 939383 complement(1250016..1250504) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766913, 7519271, 8509331; Product type cp: cell process; spore coat protein Y 1250504 cotY 939383 cotY Bacillus subtilis subsp. subtilis str. 168 spore coat protein Y NP_389057.1 1250016 R 224308 CDS NP_389058.1 16078241 936417 complement(1250656..1251174) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10400595, 10788508, 12031481, 7519271, 8509331; Product type cp: cell process; spore coat protein X 1251174 cotX 936417 cotX Bacillus subtilis subsp. subtilis str. 168 spore coat protein X NP_389058.1 1250656 R 224308 CDS NP_389059.1 16078242 939374 complement(1251273..1251590) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8509331; Product type cp: cell process; spore coat protein W 1251590 cotW 939374 cotW Bacillus subtilis subsp. subtilis str. 168 spore coat protein W NP_389059.1 1251273 R 224308 CDS NP_389060.1 16078243 939385 complement(1251631..1252017) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7519271, 8509331; Product type cp: cell process; spore coat protein V 1252017 cotV 939385 cotV Bacillus subtilis subsp. subtilis str. 168 spore coat protein V NP_389060.1 1251631 R 224308 CDS NP_389061.1 16078244 936428 1252177..1252533 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 15849754, 16850406; Product type cp: cell process; sporulation protein YjcA 1252533 yjcA 936428 yjcA Bacillus subtilis subsp. subtilis str. 168 sporulation protein YjcA NP_389061.1 1252177 D 224308 CDS YP_003097704.1 255767263 8303173 1252815..1253021 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1253021 yjzK 8303173 yjzK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097704.1 1252815 D 224308 CDS YP_003097705.1 255767264 8303203 1253103..1253252 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14523132; Product type h : extrachromosomal origin; hypothetical protein 1253252 yjcZ 8303203 yjcZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097705.1 1253103 D 224308 CDS NP_389063.2 255767265 939384 1253385..1253639 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14523132, 14702409; Product type cp: cell process; sporulation-specific transcription factor SpoVIF 1253639 spoVIF 939384 spoVIF Bacillus subtilis subsp. subtilis str. 168 sporulation-specific transcription factor SpoVIF NP_389063.2 1253385 D 224308 CDS NP_389064.2 255767266 939813 complement(1253713..1255866) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544244; Product type pe : enzyme; ATP-dependent DNA helicase 1255866 yjcD 939813 yjcD Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA helicase NP_389064.2 1253713 R 224308 CDS YP_003097706.1 255767267 8303175 1256109..1256363 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 11976315; hypothetical protein 1256363 yjzE 8303175 yjzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097706.1 1256109 D 224308 CDS NP_389066.1 16078249 939387 complement(1256436..1256858) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YjcF 1256858 yjcF 939387 yjcF Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YjcF NP_389066.1 1256436 R 224308 CDS NP_389067.1 16078250 939822 complement(1256862..1257377) 1 NC_000964.3 similar to 2'-5' RNA ligase; hypothetical protein 1257377 yjcG 939822 yjcG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389067.1 1256862 R 224308 CDS NP_389068.1 16078251 936425 complement(1257414..1258136) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1258136 yjcH 936425 yjcH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389068.1 1257414 R 224308 CDS NP_389069.1 16078252 939812 1258492..1259613 1 NC_000964.3 catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity; cystathionine gamma-synthase/O-acetylhomoserine 1259613 yjcI 939812 yjcI Bacillus subtilis subsp. subtilis str. 168 cystathionine gamma-synthase/O-acetylhomoserine NP_389069.1 1258492 D 224308 CDS NP_389070.1 16078253 936424 1259606..1260778 1 NC_000964.3 catalyzes the formation of L-homocysteine from cystathionine; cystathionine beta-lyase MetC 1260778 yjcJ 936424 yjcJ Bacillus subtilis subsp. subtilis str. 168 cystathionine beta-lyase MetC NP_389070.1 1259606 D 224308 CDS NP_389071.1 16078254 939406 complement(1260811..1261356) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2828880; Product type pe : enzyme; ribosomal-protein-alanine acetyltransferase 1261356 yjcK 939406 yjcK Bacillus subtilis subsp. subtilis str. 168 ribosomal-protein-alanine acetyltransferase NP_389071.1 1260811 R 224308 CDS NP_389072.1 16078255 936434 complement(1261426..1262616) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1262616 yjcL 936434 yjcL Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389072.1 1261426 R 224308 CDS NP_389073.1 16078256 939395 complement(1263702..1264931) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1264931 yjcM 939395 yjcM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389073.1 1263702 R 224308 CDS NP_389074.1 16078257 939817 1265057..1265377 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1265377 yjcN 939817 yjcN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389074.1 1265057 D 224308 CDS YP_003097707.1 255767268 8303198 1265530..1265661 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1265661 yjzF 8303198 yjzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097707.1 1265530 D 224308 CDS YP_003097708.1 255767269 8303177 1265677..1265850 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1265850 yjzG 8303177 yjzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097708.1 1265677 D 224308 CDS NP_389075.1 16078258 936430 1265887..1266348 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 1266348 yjcO 936430 yjcO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389075.1 1265887 D 224308 CDS NP_389076.1 16078259 936429 1266614..1267117 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1267117 yjcP 936429 yjcP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389076.1 1266614 D 224308 CDS NP_389077.1 16078260 939821 1267129..1267413 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1267413 yjcQ 939821 yjcQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389077.1 1267129 D 224308 CDS NP_389078.1 16078261 936443 1267574..1268101 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7489895, 7704261; Product type pe: enzyme; hypothetical protein 1268101 yjcR 936443 yjcR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389078.1 1267574 D 224308 CDS NP_389079.1 16078262 939400 1268275..1268592 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1268592 yjcS 939400 yjcS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389079.1 1268275 D 224308 CDS NP_389080.1 16078263 939818 1268829..1269584 1 NC_000964.3 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 1269584 yjdA 939818 yjdA Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389080.1 1268829 D 224308 CDS NP_389081.1 16078264 936431 complement(1269733..1270080) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1270080 yjdB 936431 yjdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389081.1 1269733 R 224308 CDS NP_389082.2 255767270 939394 1270631..1272577 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438772, 10960106; Product type r : regulator; transcriptional regulator ManR 1272577 manR 939394 manR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator ManR NP_389082.2 1270631 D 224308 CDS NP_389083.2 255767271 936437 1272725..1274677 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10627040, 10960106; Product type t: transporter; PTS system mannose-specific EIIBCA component 1274677 manP 936437 manP Bacillus subtilis subsp. subtilis str. 168 PTS system mannose-specific EIIBCA component NP_389083.2 1272725 D 224308 CDS NP_389084.1 16078267 939393 1274692..1275639 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 7934877; Product type e: enzyme; mannose-6-phosphate isomerase ManA 1275639 manA 939393 manA Bacillus subtilis subsp. subtilis str. 168 mannose-6-phosphate isomerase ManA NP_389084.1 1274692 D 224308 CDS NP_389085.1 16078268 939820 1275809..1276291 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1276291 yjdF 939820 yjdF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389085.1 1275809 D 224308 CDS NP_389086.1 16078269 936436 complement(1276337..1276843) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YjdG 1276843 yjdG 936436 yjdG Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YjdG NP_389086.1 1276337 R 224308 CDS NP_389087.2 255767272 939819 complement(1277062..1277457) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1277457 yjdH 939819 yjdH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389087.2 1277062 R 224308 CDS NP_389088.1 16078271 936435 1277686..1278165 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; Cys-tRNA 1278165 yjdI 936435 yjdI Bacillus subtilis subsp. subtilis str. 168 Cys-tRNA NP_389088.1 1277686 D 224308 CDS YP_003097709.1 255767273 8303219 complement(1278205..1278399) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1278399 yjzH 8303219 yjzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097709.1 1278205 R 224308 CDS NP_389089.1 16078272 936449 complement(1278565..1278894) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1278894 yjdJ 936449 yjdJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389089.1 1278565 R 224308 CDS NP_389090.2 255767274 939825 complement(1279514..1280503) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15491161, 15849754, 16850406; Product type e: enzyme; protoheme IX farnesyltransferase 1280503 ctaO 939825 ctaO Bacillus subtilis subsp. subtilis str. 168 protoheme IX farnesyltransferase NP_389090.2 1279514 R 224308 CDS NP_389091.1 16078274 939403 complement(1280626..1280949) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1391045, 1917883; Product type cp: cell process; spore coat protein 1280949 cotT 939403 cotT Bacillus subtilis subsp. subtilis str. 168 spore coat protein NP_389091.1 1280626 R 224308 CDS NP_389092.1 16078275 936440 1281128..1282531 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679227, 17878218; Product type e: enzyme; hypothetical protein 1282531 yjeA 936440 yjeA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389092.1 1281128 D 224308 CDS NP_389093.1 16078276 939830 complement(1282571..1283044) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1283044 yjfA 939830 yjfA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389093.1 1282571 R 224308 CDS NP_389094.1 16078277 936446 complement(1283169..1283336) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1283336 yjfB 936446 yjfB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389094.1 1283169 R 224308 CDS NP_389095.2 255767275 939398 1283463..1284362 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1284362 yjfC 939398 yjfC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389095.2 1283463 D 224308 CDS NP_389096.1 16078279 939397 complement(1284371..1284769) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406; membrane protein 1284769 yjgA 939397 yjgA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389096.1 1284371 R 224308 CDS NP_389097.1 16078280 936448 complement(1284870..1285445) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 1580552; hypothetical protein 1285445 yjgB 936448 yjgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389097.1 1284870 R 224308 CDS NP_389098.1 16078281 939396 1285591..1288548 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1288548 yjgC 939396 yjgC Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389098.1 1285591 D 224308 CDS NP_389099.1 16078282 939826 1288541..1289101 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1289101 yjgD 939826 yjgD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389099.1 1288541 D 224308 CDS NP_389100.1 16078283 936457 1289298..1289939 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 1289939 yjhA 936457 yjhA Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_389100.1 1289298 D 224308 CDS NP_389101.2 255767276 939419 1290018..1290644 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12483591, 16513759; Product type pe: enzyme; ADP-ribose pyrophosphatase YjhB 1290644 yjhB 939419 yjhB Bacillus subtilis subsp. subtilis str. 168 ADP-ribose pyrophosphatase YjhB NP_389101.2 1290018 D 224308 CDS NP_389102.1 16078285 939399 complement(1290675..1290953) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1290953 yjiA 939399 yjiA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389102.1 1290675 R 224308 CDS NP_389103.1 16078286 936452 1291344..1292534 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; cytochrome P450 YjiB 1292534 yjiB 936452 yjiB Bacillus subtilis subsp. subtilis str. 168 cytochrome P450 YjiB NP_389103.1 1291344 D 224308 CDS NP_389104.1 16078287 939402 1292557..1293735 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YjiC 1293735 yjiC 939402 yjiC Bacillus subtilis subsp. subtilis str. 168 UDP-glucosyltransferase YjiC NP_389104.1 1292557 D 224308 CDS YP_003097710.1 255767277 8302936 complement(1293776..1293964) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1293964 yjzI 8302936 yjzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097710.1 1293776 R 224308 CDS NP_389105.1 16078288 939823 1294138..1294950 1 NC_000964.3 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis; hypothetical protein 1294950 hemD 939823 hemD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389105.1 1294138 D 224308 CDS NP_389106.1 16078289 936453 complement(1294996..1295748) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 1295748 yjkA 936453 yjkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389106.1 1294996 R 224308 CDS NP_389107.1 16078290 939401 complement(1295748..1296500) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 1296500 yjkB 939401 yjkB Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389107.1 1295748 R 224308 CDS NP_389108.1 16078291 939404 complement(1296620..1297594) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 1297594 yjlA 939404 yjlA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389108.1 1296620 R 224308 CDS NP_389109.1 16078292 939411 1297726..1298223 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10704478; hypothetical protein 1298223 yjlB 939411 yjlB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389109.1 1297726 D 224308 CDS NP_389110.1 16078293 939407 1298612..1299034 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645; Product type r: regulator; hypothetical protein 1299034 rex 939407 rex Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389110.1 1298612 D 224308 CDS NP_389111.1 16078294 939832 1299074..1300252 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17015645, 6816592; Product type e: enzyme; NADH dehydrogenase-like protein YjlD 1300252 ndh 939832 ndh Bacillus subtilis subsp. subtilis str. 168 NADH dehydrogenase-like protein YjlD NP_389111.1 1299074 D 224308 CDS NP_389112.1 16078295 936461 1300450..1301871 1 NC_000964.3 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism; uronate isomerase 1301871 uxaC 936461 uxaC Bacillus subtilis subsp. subtilis str. 168 uronate isomerase NP_389112.1 1300450 D 224308 CDS NP_389113.1 16078296 939410 1301939..1303318 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9882655; Product type t: transporter; symporter 1303318 exuM 939410 exuM Bacillus subtilis subsp. subtilis str. 168 symporter NP_389113.1 1301939 D 224308 CDS NP_389114.1 16078297 939828 1303423..1304436 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16788182, 9579062, 9882655; Product type pe: enzyme; oxidoreductase 1304436 yjmC 939828 yjmC Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389114.1 1303423 D 224308 CDS NP_389115.1 16078298 936463 1304442..1305461 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9579062, 9882655; Product type pe: enzyme; zinc-type alcohol dehydrogenase 1305461 yjmD 936463 yjmD Bacillus subtilis subsp. subtilis str. 168 zinc-type alcohol dehydrogenase NP_389115.1 1304442 D 224308 CDS NP_389116.1 16078299 939409 1305486..1306565 1 NC_000964.3 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate; mannonate dehydratase 1306565 uxuA 939409 uxuA Bacillus subtilis subsp. subtilis str. 168 mannonate dehydratase NP_389116.1 1305486 D 224308 CDS NP_389117.1 16078300 939418 1306562..1307398 1 NC_000964.3 Converts D-mannonate to D-mannuronate; oxidoreductase 1307398 yjmF 939418 yjmF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389117.1 1306562 D 224308 CDS NP_389118.1 16078301 939405 1307446..1308714 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8320243, 9579062, 9882655; Product type t: transporter; hexuronate transporter 1308714 exuT 939405 exuT Bacillus subtilis subsp. subtilis str. 168 hexuronate transporter NP_389118.1 1307446 D 224308 CDS NP_389119.1 16078302 939834 1308802..1309803 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9579062, 9882655; Product type r: regulator; LacI family transcriptional regulator 1309803 exuR 939834 exuR Bacillus subtilis subsp. subtilis str. 168 LacI family transcriptional regulator NP_389119.1 1308802 D 224308 CDS NP_389120.1 16078303 936468 1309880..1311322 1 NC_000964.3 catalyzes the formation of D-tagaturonate from D-altronate; altronate oxidoreductase 1311322 uxaB 936468 uxaB Bacillus subtilis subsp. subtilis str. 168 altronate oxidoreductase NP_389120.1 1309880 D 224308 CDS NP_389121.2 255767278 939837 1311319..1312812 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9579062, 9882655; Product type e: enzyme; altronate dehydratase 1312812 uxaA 939837 uxaA Bacillus subtilis subsp. subtilis str. 168 altronate dehydratase NP_389121.2 1311319 D 224308 CDS NP_389122.1 16078305 939412 complement(1312851..1313615) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1313615 yjnA 939412 yjnA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389122.1 1312851 R 224308 CDS NP_389123.1 16078306 939416 complement(1313840..1314304) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1314304 yjoA 939416 yjoA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389123.1 1313840 R 224308 CDS NP_389124.1 16078307 936467 1314453..1315724 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14757246; Product type e: enzyme; ATPase YjoB 1315724 yjoB 936467 yjoB Bacillus subtilis subsp. subtilis str. 168 ATPase YjoB NP_389124.1 1314453 D 224308 CDS NP_389125.1 16078308 939417 1315869..1317005 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587784, 15805512, 15916600; Product type e: enzyme; response regulator aspartate phosphatase A 1317005 rapA 939417 rapA Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase A NP_389125.1 1315869 D 224308 CDS NP_389126.1 16078309 939413 1316995..1317129 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 11587784, 16816200; Product type f: factor; phosphatase RapA inhibitor 1317129 phrA 939413 phrA Bacillus subtilis subsp. subtilis str. 168 phosphatase RapA inhibitor NP_389126.1 1316995 D 224308 CDS NP_389127.2 255767279 939831 complement(1317157..1317414) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15779043; Product type pe : enzyme; hypothetical protein 1317414 yjpA 939831 yjpA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389127.2 1317157 R 224308 CDS NP_389128.1 16078311 936464 1317535..1318488 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915, 9555893; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase XlyB 1318488 xlyB 936464 xlyB Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase XlyB NP_389128.1 1317535 D 224308 CDS NP_389129.1 16078312 939415 complement(1318528..1318905) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; Product type h: extrachromosomal origin; hypothetical protein 1318905 yjqA 939415 yjqA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389129.1 1318528 R 224308 CDS NP_389130.1 16078313 939423 1319011..1319613 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin; hypothetical protein 1319613 yjqB 939423 yjqB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389130.1 1319011 D 224308 CDS NP_389131.2 255767280 939414 1319690..1320526 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466572, 8760915; Product type h: extrachromosomal origin; hypothetical protein 1320526 yjqC 939414 yjqC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389131.2 1319690 D 224308 CDS NP_389132.3 255767281 939838 complement(1320570..1321166) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267290, 8760915; Product type h: extrachromosomal origin; phage-like element PBSX protein XkdA 1321166 xkdA 939838 xkdA Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdA NP_389132.3 1320570 R 224308 CDS NP_389133.1 16078316 936473 complement(1321329..1321670) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8083175; Product type h : extrachromosomal origin; XRE family transcriptional regulator 1321670 xre 936473 xre Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389133.1 1321329 R 224308 CDS YP_003097711.1 255767282 8303027 1321848..1322027 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1322027 yjzJ 8303027 yjzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097711.1 1321848 D 224308 CDS NP_389134.2 255767283 939420 1322014..1322850 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdB 1322850 xkdB 939420 xkdB Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdB NP_389134.2 1322014 D 224308 CDS NP_389135.2 255767284 939841 1322750..1323550 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdC 1323550 xkdC 939841 xkdC Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdC NP_389135.2 1322750 D 224308 CDS YP_003097712.1 255767285 8303179 1323550..1323717 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1323717 ykzK 8303179 ykzK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097712.1 1323550 D 224308 CDS NP_389136.1 16078319 936466 1323802..1324152 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdD 1324152 xkdD 936466 xkdD Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdD NP_389136.1 1323802 D 224308 CDS NP_389137.1 16078320 939839 1324149..1324355 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8760915; Product type h : extrachromosomal origin; phage-like element PBSX protein XtrA 1324355 xtrA 939839 xtrA Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XtrA NP_389137.1 1324149 D 224308 CDS NP_389138.1 16078321 936474 1324471..1324980 1 NC_000964.3 Positive regulatory protein that acts at the late promoter PL; positive control factor 1324980 xpf 936474 xpf Bacillus subtilis subsp. subtilis str. 168 positive control factor NP_389138.1 1324471 D 224308 CDS NP_389139.1 16078322 939835 1325096..1325893 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8083174; Product type e: enzyme; PBSX phage terminase small subunit 1325893 xtmA 939835 xtmA Bacillus subtilis subsp. subtilis str. 168 PBSX phage terminase small subunit NP_389139.1 1325096 D 224308 CDS NP_389140.1 16078323 939426 1325890..1327191 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; PBSX phage terminase large subunit 1327191 xtmB 939426 xtmB Bacillus subtilis subsp. subtilis str. 168 PBSX phage terminase large subunit NP_389140.1 1325890 D 224308 CDS NP_389141.2 255767286 936471 1327195..1328682 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; phage-like element PBSX protein XkdE 1328682 xkdE 936471 xkdE Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdE NP_389141.2 1327195 D 224308 CDS NP_389142.2 255767287 939833 1328702..1329529 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdF 1329529 xkdF 939833 xkdF Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdF NP_389142.2 1328702 D 224308 CDS NP_389143.1 16078326 939845 1329555..1330490 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; phage-like element PBSX protein XkdG 1330490 xkdG 939845 xkdG Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdG NP_389143.1 1329555 D 224308 CDS YP_003097713.1 255767288 8302945 1330512..1330895 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1330895 ykzL 8302945 ykzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097713.1 1330512 D 224308 CDS NP_389144.1 16078327 936470 1330892..1331248 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdH 1331248 xkdH 936470 xkdH Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdH NP_389144.1 1330892 D 224308 CDS NP_389145.1 16078328 939425 1331245..1331730 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdI 1331730 xkdI 939425 xkdI Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdI NP_389145.1 1331245 D 224308 CDS NP_389146.1 16078329 936496 1331743..1332183 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdJ 1332183 xkdJ 936496 xkdJ Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdJ NP_389146.1 1331743 D 224308 CDS YP_003097714.1 255767289 8303162 1332187..1332405 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1332405 ykzM 8303162 ykzM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097714.1 1332187 D 224308 CDS NP_389147.2 255767290 939943 1332402..1333802 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdK 1333802 xkdK 939943 xkdK Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdK NP_389147.2 1332402 D 224308 CDS NP_389148.1 16078331 938181 1333804..1334247 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdM 1334247 xkdM 938181 xkdM Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdM NP_389148.1 1333804 D 224308 CDS NP_389149.2 255767291 939842 1334339..1334785 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdN 1334785 xkdN 939842 xkdN Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdN NP_389149.2 1334339 D 224308 CDS YP_003097715.1 255767292 8303192 1334815..1334964 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1334964 xkzB 8303192 xkzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097715.1 1334815 D 224308 CDS NP_389150.2 255767293 936500 1334966..1338964 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdO 1338964 xkdO 936500 xkdO Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdO NP_389150.2 1334966 D 224308 CDS NP_389151.2 255767294 939946 1338957..1339616 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; phage-like element PBSX protein XkdP 1339616 xkdP 939946 xkdP Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdP NP_389151.2 1338957 D 224308 CDS NP_389152.1 16078335 938173 1339632..1340609 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdQ 1340609 xkdQ 938173 xkdQ Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdQ NP_389152.1 1339632 D 224308 CDS NP_389153.1 16078336 939427 1340609..1340875 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdR 1340875 xkdR 939427 xkdR Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdR NP_389153.1 1340609 D 224308 CDS NP_389154.1 16078337 939840 1340932..1341357 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdS 1341357 xkdS 939840 xkdS Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdS NP_389154.1 1340932 D 224308 CDS NP_389155.1 16078338 936475 1341350..1342396 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; phage-like element PBSX protein XkdT 1342396 xkdT 936475 xkdT Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdT NP_389155.1 1341350 D 224308 CDS NP_389156.1 16078339 936476 1342380..1342958 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdU 1342958 xkdU 936476 xkdU Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdU NP_389156.1 1342380 D 224308 CDS YP_003097716.1 255767295 8303196 1342955..1343227 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1343227 xkzA 8303196 xkzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097716.1 1342955 D 224308 CDS NP_389158.1 16078340 939421 1343230..1345293 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdV 1345293 xkdV 939421 xkdV Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdV NP_389158.1 1343230 D 224308 CDS NP_389159.1 16078341 936237 1345305..1345634 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdW 1345634 xkdW 936237 xkdW Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdW NP_389159.1 1345305 D 224308 CDS NP_389160.1 16078342 939941 1345631..1345795 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; phage-like element PBSX protein XkdX 1345795 xkdX 939941 xkdX Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XkdX NP_389160.1 1345631 D 224308 CDS NP_389161.2 255767296 938161 1345839..1346678 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; phage-like element PBSX protein XepA 1346678 xepA 938161 xepA Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XepA NP_389161.2 1345839 D 224308 CDS NP_389162.1 16078344 936210 1346731..1347000 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; phage-like element PBSX protein XhlA 1347000 xhlA 936210 xhlA Bacillus subtilis subsp. subtilis str. 168 phage-like element PBSX protein XhlA NP_389162.1 1346731 D 224308 CDS NP_389163.1 16078345 939732 1347013..1347276 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2110147, 9555893; Product type h: extrachromosomal origin; holin 1347276 xhlB 939732 xhlB Bacillus subtilis subsp. subtilis str. 168 holin NP_389163.1 1347013 D 224308 CDS NP_389164.1 16078346 939869 1347289..1348182 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921239, 9555893; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase XlyA 1348182 xlyA 939869 xlyA Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase XlyA NP_389164.1 1347289 D 224308 CDS NP_389165.1 16078347 938005 complement(1348442..1348612) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520; Product type f: factor; stage II sporulation protein SB 1348612 spoIISB 938005 spoIISB Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein SB NP_389165.1 1348442 R 224308 CDS NP_389166.1 16078348 938174 complement(1348612..1349358) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11371520, 18096016; Product type f: factor; stage II sporulation protein SA 1349358 spoIISA 938174 spoIISA Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein SA NP_389166.1 1348612 R 224308 CDS NP_389167.2 255767297 936281 complement(1349468..1350469) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter; low-affinity inorganic phosphate transporter 1350469 pit 936281 pit Bacillus subtilis subsp. subtilis str. 168 low-affinity inorganic phosphate transporter NP_389167.2 1349468 R 224308 CDS NP_389168.1 16078350 939843 complement(1350482..1351099) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696772; Product type pf : factor; hypothetical protein 1351099 ykaA 939843 ykaA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389168.1 1350482 R 224308 CDS NP_389169.1 16078351 936518 complement(1351375..1352691) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; serine/threonine exchanger SteT 1352691 ykbA 936518 ykbA Bacillus subtilis subsp. subtilis str. 168 serine/threonine exchanger SteT NP_389169.1 1351375 R 224308 CDS NP_389170.1 16078352 936149 1353080..1354030 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqA 1354030 mhqA 936149 mhqA Bacillus subtilis subsp. subtilis str. 168 ring-cleaving dioxygenase MhqA NP_389170.1 1353080 D 224308 CDS NP_389171.2 255767298 939775 1354285..1356435 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; mannosyltransferase YkcB 1356435 ykcB 939775 ykcB Bacillus subtilis subsp. subtilis str. 168 mannosyltransferase YkcB NP_389171.2 1354285 D 224308 CDS NP_389172.2 255767299 936326 1356447..1357418 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YkcC 1357418 ykcC 936326 ykcC Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YkcC NP_389172.2 1356447 D 224308 CDS NP_389173.2 255767300 939849 complement(1357936..1359285) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10692364, 11133960, 11555295, 12823817; Product type e: enzyme; serine protease Do-like HtrA 1359285 htrA 939849 htrA Bacillus subtilis subsp. subtilis str. 168 serine protease Do-like HtrA NP_389173.2 1357936 R 224308 CDS NP_389174.1 16078356 936776 1359454..1360272 1 NC_000964.3 catalyzes the formation of L-proline from pyrroline-5-carboxylate; pyrroline-5-carboxylate reductase 3 1360272 proG 936776 proG Bacillus subtilis subsp. subtilis str. 168 pyrroline-5-carboxylate reductase 3 NP_389174.1 1359454 D 224308 CDS NP_389175.2 255767301 936727 1360401..1361225 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069674, 11473256; Product type e: enzyme; D-aminopeptidase 1361225 dppA 936727 dppA Bacillus subtilis subsp. subtilis str. 168 D-aminopeptidase NP_389175.2 1360401 D 224308 CDS NP_389176.1 16078358 939881 1361242..1362168 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter; dipeptide transport system permease protein DppB 1362168 dppB 939881 dppB Bacillus subtilis subsp. subtilis str. 168 dipeptide transport system permease protein DppB NP_389176.1 1361242 D 224308 CDS NP_389177.1 16078359 938038 1362174..1363136 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1766370, 7536291; Product type t: transporter; dipeptide transport system permease protein DppC 1363136 dppC 938038 dppC Bacillus subtilis subsp. subtilis str. 168 dipeptide transport system permease protein DppC NP_389177.1 1362174 D 224308 CDS NP_389178.1 16078360 938628 1363141..1364148 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7536291; Product type t : transporter; dipeptide transport ATP-binding protein DppD 1364148 dppD 938628 dppD Bacillus subtilis subsp. subtilis str. 168 dipeptide transport ATP-binding protein DppD NP_389178.1 1363141 D 224308 CDS NP_389179.2 255767302 938099 1364151..1365800 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 7783641, 8793880; Product type lp: lipoprotein; dipeptide ABC transporter substrate-binding protein 1365800 dppE 938099 dppE Bacillus subtilis subsp. subtilis str. 168 dipeptide ABC transporter substrate-binding protein NP_389179.2 1364151 D 224308 CDS NP_389180.2 255767303 938175 1365888..1366847 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10428950, 15101989; Product type pe: enzyme; murein peptide carboxypeptidase 1366847 ykfA 938175 ykfA Bacillus subtilis subsp. subtilis str. 168 murein peptide carboxypeptidase NP_389180.2 1365888 D 224308 CDS NP_389181.1 16078363 939862 1366844..1367944 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11747447, 15101989; Product type e: enzyme; L-Ala-D/L-Glu epimerase 1367944 ykfB 939862 ykfB Bacillus subtilis subsp. subtilis str. 168 L-Ala-D/L-Glu epimerase NP_389181.1 1366844 D 224308 CDS NP_389182.2 255767304 937979 1367941..1368831 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type e: enzyme; gamma-D-glutamyl-l-lysine endopeptidase 1368831 ykfC 937979 ykfC Bacillus subtilis subsp. subtilis str. 168 gamma-D-glutamyl-l-lysine endopeptidase NP_389182.2 1367941 D 224308 CDS NP_389183.2 255767305 939863 1368844..1369833 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989; Product type pt : transporter; oligopeptide transport ATP-binding protein YkfD 1369833 ykfD 939863 ykfD Bacillus subtilis subsp. subtilis str. 168 oligopeptide transport ATP-binding protein YkfD NP_389183.2 1368844 D 224308 CDS NP_389184.1 16078366 937980 complement(1369876..1370925) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 6-phosphogluconolactonase 1370925 ykgB 937980 ykgB Bacillus subtilis subsp. subtilis str. 168 6-phosphogluconolactonase NP_389184.1 1369876 R 224308 CDS NP_389185.2 255767306 939864 complement(1371015..1371875) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1371875 ykgA 939864 ykgA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389185.2 1371015 R 224308 CDS NP_389186.2 50812222 937988 1372035..1372553 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl-CoA thioester hydrolase YkhA 1372553 ykhA 937988 ykhA Bacillus subtilis subsp. subtilis str. 168 acyl-CoA thioester hydrolase YkhA NP_389186.2 1372035 D 224308 CDS NP_389187.1 16078369 939891 1372792..1373991 1 NC_000964.3 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine; flavohemoprotein 1373991 hmp 939891 hmp Bacillus subtilis subsp. subtilis str. 168 flavohemoprotein NP_389187.1 1372792 D 224308 CDS NP_389188.1 16078370 937994 complement(1374068..1374292) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1374292 ykzH 937994 ykzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389188.1 1374068 R 224308 CDS NP_389189.1 16078371 939857 1374437..1375168 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1375168 ykjA 939857 ykjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389189.1 1374437 D 224308 CDS NP_389190.1 16078372 937079 1375260..1375787 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1375787 ykkA 937079 ykkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389190.1 1375260 D 224308 CDS NP_389191.1 16078373 939859 1375777..1376295 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; hypothetical protein 1376295 ykkB 939859 ykkB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389191.1 1375777 D 224308 CDS NP_389192.1 16078374 936835 1376517..1376855 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter; multidrug resistance protein 1376855 ykkC 936835 ykkC Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_389192.1 1376517 D 224308 CDS NP_389193.1 16078375 938109 1376855..1377172 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624; Product type t: transporter; multidrug resistance protein 1377172 ykkD 938109 ykkD Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_389193.1 1376855 D 224308 CDS NP_389194.2 255767307 939854 1377243..1378145 1 NC_000964.3 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine; formyltetrahydrofolate deformylase 1378145 purU 939854 purU Bacillus subtilis subsp. subtilis str. 168 formyltetrahydrofolate deformylase NP_389194.2 1377243 D 224308 CDS NP_389195.2 255767308 936790 1378496..1379593 1 NC_000964.3 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; glutamate 5-kinase 1 1379593 proB 936790 proB Bacillus subtilis subsp. subtilis str. 168 glutamate 5-kinase 1 NP_389195.2 1378496 D 224308 CDS NP_389196.2 255767309 936166 1379605..1380852 1 NC_000964.3 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 1380852 proA 936166 proA Bacillus subtilis subsp. subtilis str. 168 gamma-glutamyl phosphate reductase NP_389196.2 1379605 D 224308 CDS NP_389197.1 16078379 939848 1380978..1381403 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418552, 17502599; Product type e: enzyme; organic hydroperoxide resistance protein OhrA 1381403 ohrA 939848 ohrA Bacillus subtilis subsp. subtilis str. 168 organic hydroperoxide resistance protein OhrA NP_389197.1 1380978 D 224308 CDS NP_389198.1 16078380 939850 complement(1381434..1381877) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11983871, 17502599, 18363800; Product type r: regulator; organic hydroperoxide resistance transcriptional regulator 1381877 ohrR 939850 ohrR Bacillus subtilis subsp. subtilis str. 168 organic hydroperoxide resistance transcriptional regulator NP_389198.1 1381434 R 224308 CDS NP_389199.1 16078381 936734 1382020..1382430 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11418552, 18084074, 9696771; Product type e : enzyme; organic hydroperoxide resistance protein OhrB 1382430 ohrB 936734 ohrB Bacillus subtilis subsp. subtilis str. 168 organic hydroperoxide resistance protein OhrB NP_389199.1 1382020 D 224308 CDS YP_003097717.1 255767310 8302905 1382457..1382627 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1382627 ykzN 8302905 ykzN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097717.1 1382457 D 224308 CDS NP_389200.1 16078382 936695 complement(1382677..1383147) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11101664, 15180998; Product type e: enzyme; guanine deaminase 1383147 guaD 936695 guaD Bacillus subtilis subsp. subtilis str. 168 guanine deaminase NP_389200.1 1382677 R 224308 CDS NP_389201.2 255767311 936480 complement(1383320..1385608) 1 NC_000964.3 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1385608 metE 936480 metE Bacillus subtilis subsp. subtilis str. 168 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase NP_389201.2 1383320 R 224308 CDS NP_389202.1 16078384 939934 complement(1386024..1386983) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680823, 3087947; Product type e: enzyme; major intracellular serine protease 1386983 ispA 939934 ispA Bacillus subtilis subsp. subtilis str. 168 major intracellular serine protease NP_389202.1 1386024 R 224308 CDS NP_389203.1 16078385 938160 1387206..1388039 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor; RsbT co-antagonist protein RsbRB 1388039 rsbRB 938160 rsbRB Bacillus subtilis subsp. subtilis str. 168 RsbT co-antagonist protein RsbRB NP_389203.1 1387206 D 224308 CDS NP_389204.1 16078386 939836 complement(1388070..1388834) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; HMP/thiamine permease protein YkoC 1388834 thiX 939836 thiX Bacillus subtilis subsp. subtilis str. 168 HMP/thiamine permease protein YkoC NP_389204.1 1388070 R 224308 CDS NP_389205.2 255767312 936472 complement(1388809..1390452) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16291685, 16356850; Product type t: transporter; HMP/thiamine import ATP-binding protein YkoD 1390452 thiW 936472 thiW Bacillus subtilis subsp. subtilis str. 168 HMP/thiamine import ATP-binding protein YkoD NP_389205.2 1388809 R 224308 CDS NP_389206.2 255767313 939829 complement(1390439..1391038) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; HMP/thiamine permease protein YkoE 1391038 thiV 939829 thiV Bacillus subtilis subsp. subtilis str. 168 HMP/thiamine permease protein YkoE NP_389206.2 1390439 R 224308 CDS NP_389207.1 16078389 936465 complement(1391040..1391642) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15451668, 16291685, 16356850; Product type f: factor; HMP/thiamine-binding protein YkoF 1391642 thiU 936465 thiU Bacillus subtilis subsp. subtilis str. 168 HMP/thiamine-binding protein YkoF NP_389207.1 1391040 R 224308 CDS NP_389208.1 16078390 936451 1391953..1392639 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 1392639 ykoG 936451 ykoG Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_389208.1 1391953 D 224308 CDS NP_389209.1 16078391 936458 1392643..1394007 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 1394007 ykoH 936458 ykoH Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_389209.1 1392643 D 224308 CDS NP_389210.1 16078392 939827 1394004..1394684 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1394684 ykoI 939827 ykoI Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389210.1 1394004 D 224308 CDS NP_389211.1 16078393 936459 1394776..1395288 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17209068; Product type ph : phenotype; hypothetical protein 1395288 ykoJ 936459 ykoJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389211.1 1394776 D 224308 CDS NP_389212.1 16078394 936450 1395371..1395508 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1395508 ykzD 936450 ykzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389212.1 1395371 D 224308 CDS NP_389213.1 16078395 936439 1396013..1397368 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15096624; Product type t: transporter; magnesium transporter MgtE 1397368 mgtE 936439 mgtE Bacillus subtilis subsp. subtilis str. 168 magnesium transporter MgtE NP_389213.1 1396013 D 224308 CDS NP_389214.1 16078396 936445 complement(1397411..1397743) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10231480, 12823818, 15916606, 16547045, 17085574, 17183219; Product type r : regulator; MerR family transcriptional regulator 1397743 tnrA 936445 tnrA Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_389214.1 1397411 R 224308 CDS NP_389215.1 16078397 939392 1397938..1398093 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441; hypothetical protein 1398093 ykzB 939392 ykzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389215.1 1397938 D 224308 CDS NP_389216.1 16078398 939391 1398181..1398363 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 10671441; stress response protein YkoL 1398363 ykoL 939391 ykoL Bacillus subtilis subsp. subtilis str. 168 stress response protein YkoL NP_389216.1 1398181 D 224308 CDS NP_389217.1 16078399 939824 1398496..1398960 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 1398960 ykoM 939824 ykoM Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_389217.1 1398496 D 224308 CDS NP_389218.2 255767314 939390 complement(1398975..1400096) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase 1400096 ykoN 939390 ykoN Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase NP_389218.2 1398975 R 224308 CDS NP_389219.2 255767315 936444 1400188..1400739 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1400739 ykoP 936444 ykoP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389219.2 1400188 D 224308 CDS NP_389220.1 16078402 939388 complement(1400767..1401579) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase 1401579 ykoQ 939388 ykoQ Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_389220.1 1400767 R 224308 CDS NP_389221.1 16078403 939380 1401772..1403466 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1403466 ykoS 939380 ykoS Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389221.1 1401772 D 224308 CDS NP_389222.1 16078404 939378 1403479..1404492 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YkoT 1404492 ykoT 939378 ykoT Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YkoT NP_389222.1 1403479 D 224308 CDS NP_389223.1 16078405 939372 complement(1404518..1406353) 1 NC_000964.3 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; ATP-dependent DNA ligase YkoU 1406353 ligD 939372 ligD Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA ligase YkoU NP_389223.1 1404518 R 224308 CDS NP_389224.1 16078406 939375 complement(1406357..1407292) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11095673, 12215643, 16497325, 16780573; Product type e: enzyme; DNA repair protein YkoV 1407292 ykoV 939375 ykoV Bacillus subtilis subsp. subtilis str. 168 DNA repair protein YkoV NP_389224.1 1406357 R 224308 CDS YP_054577.1 50812223 2914252 complement(1407329..1409578) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11728710; Product type prc : receptor; diguanylate cyclase 1409578 dgcW 2914252 dgcW Bacillus subtilis subsp. subtilis str. 168 diguanylate cyclase YP_054577.1 1407329 R 224308 CDS NP_389226.1 16078407 939381 1409912..1410577 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1410577 ykoX 939381 ykoX Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389226.1 1409912 D 224308 CDS NP_389227.1 16078408 939368 1410654..1411628 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624, 15849754, 16850406; Product type pt: transporter; membrane protein 1411628 ykoY 939368 ykoY Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389227.1 1410654 D 224308 CDS NP_389228.1 16078409 939363 1411892..1412647 1 NC_000964.3 Heat shock-induced; RNA polymerase sigma factor SigI 1412647 sigI 939363 sigI Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigI NP_389228.1 1411892 D 224308 CDS NP_389229.1 16078410 939360 1412644..1413789 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17185538; Product type f: factor; anti-sigma-I factor RsgI 1413789 rsgI 939360 rsgI Bacillus subtilis subsp. subtilis str. 168 anti-sigma-I factor RsgI NP_389229.1 1412644 D 224308 CDS NP_389230.1 16078411 939362 complement(1413800..1413994) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3009397, 3112127, 3121585, 9852018; Product type f: factor; small acid-soluble spore protein D 1413994 sspD 939362 sspD Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein D NP_389230.1 1413800 R 224308 CDS NP_389231.1 16078412 939367 complement(1414125..1414826) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1414826 ykrK 939367 ykrK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389231.1 1414125 R 224308 CDS NP_389232.1 16078413 939359 1414997..1415893 1 NC_000964.3 metalloprotease; protease HtpX homolog 1415893 ykrL 939359 ykrL Bacillus subtilis subsp. subtilis str. 168 protease HtpX homolog NP_389232.1 1414997 D 224308 CDS NP_389233.1 16078414 939342 1416067..1417416 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406; Product type t: transporter; ktr system potassium uptake protein D 1417416 ktrD 939342 ktrD Bacillus subtilis subsp. subtilis str. 168 ktr system potassium uptake protein D NP_389233.1 1416067 D 224308 CDS YP_003097718.1 255767316 8303057 1417561..1417716 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1417716 ykzP 8303057 ykzP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097718.1 1417561 D 224308 CDS NP_389234.1 16078415 939354 1417719..1417895 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1417895 ykzE 939354 ykzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389234.1 1417719 D 224308 CDS NP_389235.1 16078416 939356 complement(1417938..1418960) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; membrane-bound acyltransferase YkrP 1418960 ykrP 939356 ykrP Bacillus subtilis subsp. subtilis str. 168 membrane-bound acyltransferase YkrP NP_389235.1 1417938 R 224308 CDS NP_389236.1 16078417 939349 1419213..1421429 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 12169614, 16166384; Product type rc: receptor; sporulation kinase E 1421429 kinE 939349 kinE Bacillus subtilis subsp. subtilis str. 168 sporulation kinase E NP_389236.1 1419213 D 224308 CDS NP_389237.1 16078418 939332 1421426..1421923 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2308822, 2359121; Product type e: enzyme; methylated-dna--protein-cysteine methyltransferase 1421923 ogt 939332 ogt Bacillus subtilis subsp. subtilis str. 168 methylated-dna--protein-cysteine methyltransferase NP_389237.1 1421426 D 224308 CDS NP_389238.1 16078419 939341 complement(1422172..1423233) 1 NC_000964.3 isomerizes methylthioribose-1-phosphate into methylthioribulose-1-phosphate; involved in methionine salvage pathway; methylthioribose-1-phosphate isomerase 1423233 mtnA 939341 mtnA Bacillus subtilis subsp. subtilis str. 168 methylthioribose-1-phosphate isomerase NP_389238.1 1422172 R 224308 CDS NP_389239.1 16078420 939336 complement(1423241..1424440) 1 NC_000964.3 phosphorylates methylthioribose to form methylthioribose-1-phosphate; involved in methionine salvage pathway; methylthioribose kinase 1424440 mtnK 939336 mtnK Bacillus subtilis subsp. subtilis str. 168 methylthioribose kinase NP_389239.1 1423241 R 224308 CDS NP_389240.1 16078421 939328 complement(1424767..1425546) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12022921; Product type pe : enzyme; hydrolase 1425546 mtnU 939328 mtnU Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_389240.1 1424767 R 224308 CDS NP_389241.1 16078422 939330 1425641..1426837 1 NC_000964.3 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; transaminase MtnE 1426837 ykrV 939330 ykrV Bacillus subtilis subsp. subtilis str. 168 transaminase MtnE NP_389241.1 1425641 D 224308 CDS NP_389242.1 16078423 939339 1427034..1428278 1 NC_000964.3 converts 2,3-diketo-5-methylthiopentyl-1-phosphate into 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate; involved in methionine salvage; 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 1428278 mtnW 939339 mtnW Bacillus subtilis subsp. subtilis str. 168 2,3-diketo-5-methylthiopentyl-1-phosphate enolase NP_389242.1 1427034 D 224308 CDS NP_389243.1 16078424 939331 1428275..1428982 1 NC_000964.3 converts 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate to 1,2-dihydroxy-3-keto-5-methylthiopentene; involved in methionine salvage; 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase 1428982 mtnX 939331 mtnX Bacillus subtilis subsp. subtilis str. 168 2-hydroxy-3-keto-5-methylthiopentenyl-1- phosphate phosphatase NP_389243.1 1428275 D 224308 CDS NP_389244.1 16078425 939320 1428940..1429569 1 NC_000964.3 converts methylthioribulose-1-phosphate into 2,3-diketo-5-methylthiopentyl-1-phosphate; involved in methionine salvage; methylthioribulose-1-phosphate dehydratase 1429569 mtnB 939320 mtnB Bacillus subtilis subsp. subtilis str. 168 methylthioribulose-1-phosphate dehydratase NP_389244.1 1428940 D 224308 CDS NP_389245.1 16078426 939322 1429584..1430120 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10704478, 11371200, 12022880, 12402029, 15102328; Product type e: enzyme; acireductone dioxygenase 1430120 mtnD 939322 mtnD Bacillus subtilis subsp. subtilis str. 168 acireductone dioxygenase NP_389245.1 1429584 D 224308 CDS NP_389246.1 16078427 939314 complement(1430161..1430481) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1430481 ykvA 939314 ykvA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389246.1 1430161 R 224308 CDS NP_389247.1 16078428 939315 1430684..1430941 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15057450, 15916600; Product type e: enzyme; aspartyl-phosphate phosphatase Spo0E 1430941 spo0E 939315 spo0E Bacillus subtilis subsp. subtilis str. 168 aspartyl-phosphate phosphatase Spo0E NP_389247.1 1430684 D 224308 CDS NP_389248.1 16078429 939325 1431027..1431458 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1431458 eag 939325 eag Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389248.1 1431027 D 224308 CDS NP_389249.1 16078430 939300 complement(1431486..1433006) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 16166384, 10411754; Product type e: enzyme; sporulation kinase D 1433006 kinD 939300 kinD Bacillus subtilis subsp. subtilis str. 168 sporulation kinase D NP_389249.1 1431486 R 224308 CDS NP_389250.1 16078431 939303 1433199..1433636 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17725564; Product type r: regulator; MarR family transcriptional regulator 1433636 mhqR 939303 mhqR Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_389250.1 1433199 D 224308 CDS NP_389251.1 16078432 939304 complement(1433676..1434461) 1 NC_000964.3 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; motility protein B 1434461 motB 939304 motB Bacillus subtilis subsp. subtilis str. 168 motility protein B NP_389251.1 1433676 R 224308 CDS NP_389252.1 16078433 939302 complement(1434433..1435245) 1 NC_000964.3 With Mot B forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; motility protein A 1435245 motA 939302 motA Bacillus subtilis subsp. subtilis str. 168 motility protein A NP_389252.1 1434433 R 224308 CDS NP_389253.1 16078434 939289 complement(1435628..1437727) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788169, 16899079, 11069659, 9987115, 10320580; Product type e: enzyme; ATP-dependent Clp protease ATP-binding subunit ClpE 1437727 clpE 939289 clpE Bacillus subtilis subsp. subtilis str. 168 ATP-dependent Clp protease ATP-binding subunit ClpE NP_389253.1 1435628 R 224308 CDS NP_389254.1 16078435 939307 1438092..1439135 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15383836, 15849754, 16850406; Product type pt: transporter; membrane protein 1439135 ykvI 939307 ykvI Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389254.1 1438092 D 224308 CDS NP_389255.1 16078436 939292 1439448..1440107 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14660578, 16199558, 17384645, 18491386; Product type e: enzyme; 7-cyano-7-deazaguanine synthase 1440107 queC 939292 queC Bacillus subtilis subsp. subtilis str. 168 7-cyano-7-deazaguanine synthase NP_389255.1 1439448 D 224308 CDS NP_389256.1 16078437 939282 1440100..1440549 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558, 18259064; Product type e: enzyme; 6-pyruvoyl tetrahydrobiopterin synthase 1440549 queD 939282 queD Bacillus subtilis subsp. subtilis str. 168 6-pyruvoyl tetrahydrobiopterin synthase NP_389256.1 1440100 D 224308 CDS NP_389257.1 16078438 939290 1440542..1441273 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12123838, 14660578, 16199558; Product type e : enzyme; 7-carboxy-7-deazaguanine synthase 1441273 queE 939290 queE Bacillus subtilis subsp. subtilis str. 168 7-carboxy-7-deazaguanine synthase NP_389257.1 1440542 D 224308 CDS NP_389258.1 16078439 939296 1441291..1441788 1 NC_000964.3 NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; NADPH-dependent 7-cyano-7-deazaguanine reductase 1441788 ykvM 939296 ykvM Bacillus subtilis subsp. subtilis str. 168 NADPH-dependent 7-cyano-7-deazaguanine reductase NP_389258.1 1441291 D 224308 CDS NP_389259.1 16078440 939274 complement(1442347..1442703) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pr : regulator; HxlR family transcriptional regulator 1442703 ykvN 939274 ykvN Bacillus subtilis subsp. subtilis str. 168 HxlR family transcriptional regulator NP_389259.1 1442347 R 224308 CDS NP_389260.1 16078441 939276 1442872..1443618 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; oxidoreductase 1443618 ykvO 939276 ykvO Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389260.1 1442872 D 224308 CDS NP_389261.1 16078442 939278 1444099..1445298 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148, 16683018; Product type f: factor; spore protein YkvP 1445298 ykvP 939278 ykvP Bacillus subtilis subsp. subtilis str. 168 spore protein YkvP NP_389261.1 1444099 D 224308 CDS YP_003097719.1 255767317 8303133 1445314..1445541 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1445541 ykzQ 8303133 ykzQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097719.1 1445314 D 224308 CDS NP_389262.1 16078443 939273 1445638..1446336 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; glycosylase YkvQ 1446336 ykvQ 939273 ykvQ Bacillus subtilis subsp. subtilis str. 168 glycosylase YkvQ NP_389262.1 1445638 D 224308 CDS YP_003097720.1 255767318 8303134 1446317..1446568 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16683018; Product type pe : enzyme; spore-specific glycosyl hydrolase 1446568 ykzR 8303134 ykzR Bacillus subtilis subsp. subtilis str. 168 spore-specific glycosyl hydrolase YP_003097720.1 1446317 D 224308 CDS NP_389263.1 16078444 939743 1447251..1447541 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1447541 ykvR 939743 ykvR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389263.1 1447251 D 224308 CDS NP_389264.2 255767319 939299 complement(1447662..1447847) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1447847 ykvS 939299 ykvS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389264.2 1447662 R 224308 CDS YP_003097721.1 255767320 8302968 1448013..1448207 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1448207 ykzS 8302968 ykzS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097721.1 1448013 D 224308 CDS NP_389265.1 16078446 939264 1448506..1449132 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12177332, 12950927; Product type e : enzyme; hypothetical protein 1449132 ykvT 939264 ykvT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389265.1 1448506 D 224308 CDS NP_389266.1 16078447 939262 1449250..1450587 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15686839, 15849754, 16850406; Product type m: membrane component; sporulation protein YkvU 1450587 ykvU 939262 ykvU Bacillus subtilis subsp. subtilis str. 168 sporulation protein YkvU NP_389266.1 1449250 D 224308 CDS NP_389267.1 16078448 936262 1450638..1451135 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15322369, 15342593; Product type e: enzyme; sporulation thiol-disulfide oxidoreductase A 1451135 stoA 936262 stoA Bacillus subtilis subsp. subtilis str. 168 sporulation thiol-disulfide oxidoreductase A NP_389267.1 1450638 D 224308 CDS NP_389268.1 16078449 939268 1451371..1453284 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12180919, 15802251; Product type t: transporter; zinc-transporting ATPase 1453284 zosA 939268 zosA Bacillus subtilis subsp. subtilis str. 168 zinc-transporting ATPase NP_389268.1 1451371 D 224308 CDS NP_389269.1 16078450 939258 1453691..1454782 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7770058; Product type pe : enzyme; dipeptidase YkvY 1454782 ykvY 939258 ykvY Bacillus subtilis subsp. subtilis str. 168 dipeptidase YkvY NP_389269.1 1453691 D 224308 CDS NP_389270.1 16078451 936232 1455064..1456029 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LacI family transcriptional regulator 1456029 ykvZ 936232 ykvZ Bacillus subtilis subsp. subtilis str. 168 LacI family transcriptional regulator NP_389270.1 1455064 D 224308 CDS NP_389271.2 255767321 939254 1456092..1456958 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974121, 15155854, 17074746; Product type r: regulator; BglG family transcription antiterminator 1456958 glcT 939254 glcT Bacillus subtilis subsp. subtilis str. 168 BglG family transcription antiterminator NP_389271.2 1456092 D 224308 CDS NP_389272.1 16078453 939255 1457187..1459286 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1447219, 14527945, 15849754, 16850406, 8418852, 8432747, 9593197; Product type t: transporter; PTS system glucose-specific EIICBA component 1459286 ptsG 939255 ptsG Bacillus subtilis subsp. subtilis str. 168 PTS system glucose-specific EIICBA component NP_389272.1 1457187 D 224308 CDS NP_389273.1 16078454 939259 1459384..1459650 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217795, 12411438, 14527945, 15126459, 16267306, 17085448, 17142398; Product type f: factor; phosphocarrier protein HPr 1459650 ptsH 939259 ptsH Bacillus subtilis subsp. subtilis str. 168 phosphocarrier protein HPr NP_389273.1 1459384 D 224308 CDS NP_389274.2 50812224 939253 1459650..1461362 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11902727, 15155854, 15670601, 3106335; Product type e: enzyme; phosphoenolpyruvate-protein phosphotransferase 1461362 ptsI 939253 ptsI Bacillus subtilis subsp. subtilis str. 168 phosphoenolpyruvate-protein phosphotransferase NP_389274.2 1459650 D 224308 CDS NP_389275.1 16078456 939728 1461453..1461692 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 9009064, 9323362; Product type r: regulator; transcriptional regulator SplA 1461692 splA 939728 splA Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator SplA NP_389275.1 1461453 D 224308 CDS NP_389276.1 16078457 939248 1461770..1462798 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629212, 11053385, 11470912, 17293412, 9733691; Product type e: enzyme; spore photoproduct lyase 1462798 splB 939248 splB Bacillus subtilis subsp. subtilis str. 168 spore photoproduct lyase NP_389276.1 1461770 D 224308 CDS NP_389277.2 255767322 939246 complement(1462813..1463493) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YkwB 1463493 ykwB 939246 ykwB Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YkwB NP_389277.2 1462813 R 224308 CDS NP_389278.2 255767323 936206 1463628..1465595 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11722727, 12603740, 15317802, 9721285; Product type rc: receptor; methyl-accepting chemotaxis protein McpC 1465595 mcpC 936206 mcpC Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein McpC NP_389278.2 1463628 D 224308 CDS NP_389279.1 16078460 939723 1465733..1466599 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 1466599 ykwC 939723 ykwC Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389279.1 1465733 D 224308 CDS NP_389280.2 255767324 939237 complement(1466638..1467411) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1467411 ykwD 939237 ykwD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389280.2 1466638 R 224308 CDS NP_389281.1 16078462 936204 1467805..1469862 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990; Product type e: enzyme; penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall 1469862 pbpH 936204 pbpH Bacillus subtilis subsp. subtilis str. 168 penicillin-binding enzyme for formation of rod-shaped peptidoglycan cell wall NP_389281.1 1467805 D 224308 CDS NP_389282.1 16078463 939230 1470026..1471846 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11734624, 14629015, 17350039; Product type cp: cell process; sporulation kinase A 1471846 kinA 939230 kinA Bacillus subtilis subsp. subtilis str. 168 sporulation kinase A NP_389282.1 1470026 D 224308 CDS NP_389283.2 255767325 939235 complement(1471857..1473038) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12670965; Product type e: enzyme; N-acetyl-LL-diaminopimelate aminotransferase 1473038 patA 939235 patA Bacillus subtilis subsp. subtilis str. 168 N-acetyl-LL-diaminopimelate aminotransferase NP_389283.2 1471857 R 224308 CDS YP_003097722.1 255767326 8303007 complement(1473240..1473401) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 1473401 ykzT 8303007 ykzT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097722.1 1473240 R 224308 CDS NP_389284.1 16078465 939239 1473605..1474516 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11553614, 12864845, 14731274, 14993307; Product type r: regulator; chemotaxis protein CheV 1474516 cheV 939239 cheV Bacillus subtilis subsp. subtilis str. 168 chemotaxis protein CheV NP_389284.1 1473605 D 224308 CDS NP_389285.1 16078466 939225 complement(1474560..1475024) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1475024 ykyB 939225 ykyB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389285.1 1474560 R 224308 CDS NP_389286.2 255767327 939224 complement(1475150..1476442) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 1476442 ykuC 939224 ykuC Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_389286.2 1475150 R 224308 CDS NP_389287.1 16078468 939216 complement(1476518..1477012) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11011148; Product type cp: cell process; L,D-transpeptidase YkuD 1477012 ykuD 939216 ykuD Bacillus subtilis subsp. subtilis str. 168 L,D-transpeptidase YkuD NP_389287.1 1476518 R 224308 CDS NP_389288.2 255767328 939214 complement(1477069..1477929) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase 1477929 ykuE 939214 ykuE Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_389288.2 1477069 R 224308 CDS NP_389289.1 16078470 939226 1478072..1478836 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; 2,4-dienoyl-CoA reductase 1478836 ykuF 939226 ykuF Bacillus subtilis subsp. subtilis str. 168 2,4-dienoyl-CoA reductase NP_389289.1 1478072 D 224308 CDS YP_003097723.1 255767329 8303034 1479137..1480867 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250; hypothetical protein 1480867 fadG 8303034 fadG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097723.1 1479137 D 224308 CDS YP_003097724.1 255767330 8303033 1480933..1481451 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1481451 ykzU 8303033 ykzU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097724.1 1480933 D 224308 CDS NP_389291.1 16078472 939211 1481547..1482095 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1482095 ykuH 939211 ykuH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389291.1 1481547 D 224308 CDS NP_389292.1 16078473 939207 1482248..1483471 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; EAL-domain containing protein YkuI 1483471 ykuI 939207 ykuI Bacillus subtilis subsp. subtilis str. 168 EAL-domain containing protein YkuI NP_389292.1 1482248 D 224308 CDS NP_389293.1 16078474 936162 1484117..1484356 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1484356 ykuJ 936162 ykuJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389293.1 1484117 D 224308 CDS NP_389294.1 16078475 939213 1484466..1484984 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16165328; Product type pe : enzyme; hypothetical protein 1484984 ykuK 939213 ykuK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389294.1 1484466 D 224308 CDS NP_389295.1 16078476 939703 1485118..1485315 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1485315 ykzF 939703 ykzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389295.1 1485118 D 224308 CDS NP_389296.1 16078477 939199 1485453..1485896 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11985717; CBS domain-containing protein YkuL 1485896 ykuL 939199 ykuL Bacillus subtilis subsp. subtilis str. 168 CBS domain-containing protein YkuL NP_389296.1 1485453 D 224308 CDS NP_389297.1 16078478 939197 1486045..1486926 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636591, 16352834, 16395550; Product type r: regulator; LysR family transcriptional regulator 1486926 ccpC 939197 ccpC Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_389297.1 1486045 D 224308 CDS NP_389298.1 16078479 939194 1487038..1487514 1 NC_000964.3 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin 1487514 ykuN 939194 ykuN Bacillus subtilis subsp. subtilis str. 168 flavodoxin NP_389298.1 1487038 D 224308 CDS NP_389299.1 16078480 939196 1487504..1488397 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12354229; hypothetical protein 1488397 ykuO 939196 ykuO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389299.1 1487504 D 224308 CDS NP_389300.2 255767331 938811 1488413..1488868 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15449930, 17127770; Product type e: enzyme; flavodoxin-2 1488868 ykuP 938811 ykuP Bacillus subtilis subsp. subtilis str. 168 flavodoxin-2 NP_389300.2 1488413 D 224308 CDS NP_389301.2 255767332 939193 1488973..1489683 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368155, 11910040, 12682299, 14627808; Product type e: enzyme; 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 1489683 dapH 939193 dapH Bacillus subtilis subsp. subtilis str. 168 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase NP_389301.2 1488973 D 224308 CDS NP_389302.1 16078483 938805 1489753..1490877 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14627808, 17093042; Product type e : enzyme; N-acetyldiaminopimelate deacetylase 1490877 dapL 938805 dapL Bacillus subtilis subsp. subtilis str. 168 N-acetyldiaminopimelate deacetylase NP_389302.1 1489753 D 224308 CDS NP_389303.1 16078484 938799 1490939..1491184 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1491184 ykuS 938799 ykuS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389303.1 1490939 D 224308 CDS NP_389304.2 255767333 938809 complement(1491221..1492024) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12626684; Product type pt : transporter; MscS family protein YkuT 1492024 ykuT 938809 ykuT Bacillus subtilis subsp. subtilis str. 168 MscS family protein YkuT NP_389304.2 1491221 R 224308 CDS NP_389305.1 16078486 938810 1492261..1492803 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; thioredoxin 1492803 ykuU 938810 ykuU Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_389305.1 1492261 D 224308 CDS NP_389306.2 255767334 938804 1492875..1493321 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16418167; Product type e: enzyme; thiol-disulfide oxidoreductase 1493321 ykuV 938804 ykuV Bacillus subtilis subsp. subtilis str. 168 thiol-disulfide oxidoreductase NP_389306.2 1492875 D 224308 CDS NP_389307.1 16078488 938793 1493787..1494362 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15819619; Product type r: regulator; repressor rok 1494362 rok 938793 rok Bacillus subtilis subsp. subtilis str. 168 repressor rok NP_389307.1 1493787 D 224308 CDS NP_389308.1 16078489 938787 complement(1494403..1495368) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949; sporulation protein cse15 1495368 yknT 938787 yknT Bacillus subtilis subsp. subtilis str. 168 sporulation protein cse15 NP_389308.1 1494403 R 224308 CDS NP_389309.1 16078490 938791 1495505..1496104 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 10978347; Product type e: enzyme; molybdenum cofactor guanylyltransferase 1496104 mobA 938791 mobA Bacillus subtilis subsp. subtilis str. 168 molybdenum cofactor guanylyltransferase NP_389309.1 1495505 D 224308 CDS NP_389310.1 16078491 938780 1496155..1497174 1 NC_000964.3 catalyzes the formation of a high-energy acyladenylate intermediate and subsequently to the formation of a thiocarboxylate at the C termini of MoaD or ThiS in the molybdopterin or thiamin pyrophosphate biosynthesis pathways; molybdopterin-synthase adenylyltransferase 1497174 moeB 938780 moeB Bacillus subtilis subsp. subtilis str. 168 molybdopterin-synthase adenylyltransferase NP_389310.1 1496155 D 224308 CDS NP_389311.1 16078492 938797 1497192..1498484 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11428898, 12006571; Product type e : enzyme; molybdopterin molybdenumtransferase 1498484 moeA 938797 moeA Bacillus subtilis subsp. subtilis str. 168 molybdopterin molybdenumtransferase NP_389311.1 1497192 D 224308 CDS NP_389312.1 16078493 938790 1498445..1498966 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12719427, 9219527; Product type c : carrier; molybdopterin-guanine dinucleotide biosynthesis adapter protein 1498966 mobB 938790 mobB Bacillus subtilis subsp. subtilis str. 168 molybdopterin-guanine dinucleotide biosynthesis adapter protein NP_389312.1 1498445 D 224308 CDS NP_389313.1 16078494 936092 1498966..1499439 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669; Product type e: enzyme; molybdopterin synthase catalytic subunit 1499439 moaE 936092 moaE Bacillus subtilis subsp. subtilis str. 168 molybdopterin synthase catalytic subunit NP_389313.1 1498966 D 224308 CDS NP_389314.1 16078495 938785 1499432..1499665 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11135669, 17223713; Product type e : enzyme; molybdopterin synthase sulfur carrier subunit 1499665 moaD 938785 moaD Bacillus subtilis subsp. subtilis str. 168 molybdopterin synthase sulfur carrier subunit NP_389314.1 1499432 D 224308 CDS NP_389315.1 16078496 938775 1499889..1501646 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 1501646 yknU 938775 yknU Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389315.1 1499889 D 224308 CDS NP_389316.1 16078497 936087 1501658..1503472 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 1503472 yknV 936087 yknV Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389316.1 1501658 D 224308 CDS NP_389317.1 16078498 938771 1503582..1504277 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 1504277 yknW 938771 yknW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389317.1 1503582 D 224308 CDS NP_389318.1 16078499 938774 1504282..1505415 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter; efflux system component YknX 1505415 yknX 938774 yknX Bacillus subtilis subsp. subtilis str. 168 efflux system component YknX NP_389318.1 1504282 D 224308 CDS NP_389319.1 16078500 938766 1505416..1506108 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter; ABC transporter ATP-binding protein 1506108 yknY 938766 yknY Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389319.1 1505416 D 224308 CDS NP_389320.1 16078501 938803 1506105..1507298 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9987136; Product type pt : transporter; ABC transporter permease 1507298 yknZ 938803 yknZ Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_389320.1 1506105 D 224308 CDS NP_389321.1 16078502 936082 1507578..1508333 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858; Product type r: regulator; DeoR family transcriptional regulator 1508333 fruR 936082 fruR Bacillus subtilis subsp. subtilis str. 168 DeoR family transcriptional regulator NP_389321.1 1507578 D 224308 CDS NP_389322.1 16078503 938761 1508330..1509241 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14563858, 168069; Product type e: enzyme; phosphofructokinase 1509241 fruK 938761 fruK Bacillus subtilis subsp. subtilis str. 168 phosphofructokinase NP_389322.1 1508330 D 224308 CDS NP_389323.1 16078504 938757 1509256..1511163 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 118007, 200418; Product type t: transporter; PTS system fructose-specific EIIABC component 1511163 fruA 938757 fruA Bacillus subtilis subsp. subtilis str. 168 PTS system fructose-specific EIIABC component NP_389323.1 1509256 D 224308 CDS NP_389324.1 16078505 938763 1511308..1511889 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10198007, 11283286, 12897006, 9325333; Product type e: enzyme; signal peptidase I T 1511889 sipT 938763 sipT Bacillus subtilis subsp. subtilis str. 168 signal peptidase I T NP_389324.1 1511308 D 224308 CDS NP_389325.1 16078506 938768 complement(1511923..1512192) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1512192 ykoA 938768 ykoA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389325.1 1511923 R 224308 CDS NP_389326.1 16078507 936066 1512373..1513995 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10816464; Product type t: transporter; ABC transporter ATP-binding protein 1513995 ykpA 936066 ykpA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389326.1 1512373 D 224308 CDS NP_389327.1 16078508 938752 1514052..1514963 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15966718, 17229734; Product type e: enzyme; oxidoreductase 1514963 ykpB 938752 ykpB Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389327.1 1514052 D 224308 CDS NP_389328.1 16078509 938756 complement(1514997..1516229) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16088219, 9362117; Product type e: enzyme; aminopeptidase AmpS 1516229 ampS 938756 ampS Bacillus subtilis subsp. subtilis str. 168 aminopeptidase AmpS NP_389328.1 1514997 R 224308 CDS NP_389329.1 16078510 938750 complement(1516339..1516473) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1516473 ykpC 938750 ykpC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389329.1 1516339 R 224308 CDS NP_389330.1 16078511 938746 complement(1516574..1517581) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16950129; Product type f: factor; rod-share determining protein MreBH 1517581 mreBH 938746 mreBH Bacillus subtilis subsp. subtilis str. 168 rod-share determining protein MreBH NP_389330.1 1516574 R 224308 CDS NP_389331.1 16078512 938738 1517865..1518143 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159768, 17720793; Product type r: regulator; transition state regulator Abh 1518143 abh 938738 abh Bacillus subtilis subsp. subtilis str. 168 transition state regulator Abh NP_389331.1 1517865 D 224308 CDS NP_389332.1 16078513 938742 1518333..1519619 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11069677, 11673427, 7836330; Product type e: enzyme; sporulation kinase C 1519619 kinC 938742 kinC Bacillus subtilis subsp. subtilis str. 168 sporulation kinase C NP_389332.1 1518333 D 224308 CDS NP_389333.1 16078514 939408 1519635..1520468 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; gamma-glutamylcyclotransferase YkqA 1520468 ykqA 939408 ykqA Bacillus subtilis subsp. subtilis str. 168 gamma-glutamylcyclotransferase YkqA NP_389333.1 1519635 D 224308 CDS NP_389334.1 16078515 939429 1520531..1521196 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter; ktr system potassium uptake protein C 1521196 ktrC 939429 ktrC Bacillus subtilis subsp. subtilis str. 168 ktr system potassium uptake protein C NP_389334.1 1520531 D 224308 CDS NP_389335.2 255767335 939477 1521351..1523084 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8550522; Product type e : enzyme; adenine deaminase 1523084 adeC 939477 adeC Bacillus subtilis subsp. subtilis str. 168 adenine deaminase NP_389335.2 1521351 D 224308 CDS NP_389336.1 16078517 939483 complement(1523118..1524785) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15831787, 17005971, 17229210, 17512403, 18713320; Product type e : enzyme; ribonuclease J 1 1524785 rnjA 939483 rnjA Bacillus subtilis subsp. subtilis str. 168 ribonuclease J 1 NP_389336.1 1523118 R 224308 CDS NP_389337.1 16078518 939482 complement(1524791..1525000) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1525000 ykzG 939482 ykzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389337.1 1524791 R 224308 CDS NP_389338.1 16078519 939479 1525386..1526159 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YkrA 1526159 ykrA 939479 ykrA Bacillus subtilis subsp. subtilis str. 168 phosphatase YkrA NP_389338.1 1525386 D 224308 CDS NP_389339.1 16078520 939491 complement(1526195..1526749) 1 NC_000964.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1526749 def 939491 def Bacillus subtilis subsp. subtilis str. 168 peptide deformylase NP_389339.1 1526195 R 224308 CDS YP_003097725.1 255767336 8303091 complement(1526859..1527017) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1527017 ykzV 8303091 ykzV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097725.1 1526859 R 224308 CDS NP_389340.2 255767337 939487 1527231..1527902 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16684363; Product type pf : factor; lipoprotein 1527902 ykyA 939487 ykyA Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_389340.2 1527231 D 224308 CDS NP_389341.1 16078522 936005 1528326..1529441 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12469342, 1784816, 9352926, 9588797; Product type e: enzyme; pyruvate dehydrogenase E1 component subunit alpha 1529441 pdhA 936005 pdhA Bacillus subtilis subsp. subtilis str. 168 pyruvate dehydrogenase E1 component subunit alpha NP_389341.1 1528326 D 224308 CDS NP_389342.1 16078523 939496 1529445..1530422 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme; pyruvate dehydrogenase E1 component subunit beta 1530422 pdhB 939496 pdhB Bacillus subtilis subsp. subtilis str. 168 pyruvate dehydrogenase E1 component subunit beta NP_389342.1 1529445 D 224308 CDS NP_389343.1 16078524 936010 1530537..1531865 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11976308, 1784816, 9352926, 9588797; Product type e: enzyme; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex 1531865 pdhC 936010 pdhC Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex NP_389343.1 1530537 D 224308 CDS NP_389344.1 16078525 939492 1531870..1533282 1 NC_000964.3 E3 component of pyruvate complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase 1533282 pdhD 939492 pdhD Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyl dehydrogenase NP_389344.1 1531870 D 224308 CDS NP_389345.1 16078526 935991 complement(1533327..1533701) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1936936; Product type s : structure; Pal-related lipoprotein 1533701 slp 935991 slp Bacillus subtilis subsp. subtilis str. 168 Pal-related lipoprotein NP_389345.1 1533327 R 224308 CDS YP_003097726.1 255767338 8302953 1534120..1534239 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1534239 ykzW 8302953 ykzW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097726.1 1534120 D 224308 CDS NP_389346.1 16078527 936002 complement(1534279..1535751) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9723923; Product type e : enzyme; arginine decarboxylase 1535751 speA 936002 speA Bacillus subtilis subsp. subtilis str. 168 arginine decarboxylase NP_389346.1 1534279 R 224308 CDS NP_389347.1 16078528 935989 1535936..1536202 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1536202 yktA 935989 yktA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389347.1 1535936 D 224308 CDS NP_389348.1 16078529 935987 complement(1536235..1536873) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1536873 yktB 935987 yktB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389348.1 1536235 R 224308 CDS NP_389349.1 16078530 935992 1537113..1537301 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1537301 ykzI 935992 ykzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389349.1 1537113 D 224308 CDS NP_389350.1 16078531 935986 1537441..1538238 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11914086, 16682444; Product type e: enzyme; inositol-1-monophosphatase 1538238 suhB 935986 suhB Bacillus subtilis subsp. subtilis str. 168 inositol-1-monophosphatase NP_389350.1 1537441 D 224308 CDS NP_389351.1 16078532 935976 1538264..1538692 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1538692 ykzC 935976 ykzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389351.1 1538264 D 224308 CDS NP_389352.1 16078533 935978 complement(1538770..1539684) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; S-adenosyl-L-methionine-dependent methyltransferase YktD 1539684 yktD 935978 yktD Bacillus subtilis subsp. subtilis str. 168 S-adenosyl-L-methionine-dependent methyltransferase YktD NP_389352.1 1538770 R 224308 CDS NP_389353.1 16078534 935981 complement(1540036..1541601) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 2128597, 6090407, 8436952; Product type e: enzyme; bacillolysin 1541601 nprE 935981 nprE Bacillus subtilis subsp. subtilis str. 168 bacillolysin NP_389353.1 1540036 R 224308 CDS NP_389354.1 16078535 935984 1541886..1543826 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307; hypothetical protein 1543826 ylaA 935984 ylaA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389354.1 1541886 D 224308 CDS NP_389355.1 16078536 935962 1543816..1544085 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 16501307; hypothetical protein 1544085 ylaB 935962 ylaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389355.1 1543816 D 224308 CDS NP_389356.1 16078537 935973 1544085..1544606 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator; RNA polymerase sigma factor YlaC 1544606 ylaC 935973 ylaC Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor YlaC NP_389356.1 1544085 D 224308 CDS NP_389357.1 16078538 935961 1544603..1544896 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16501307, 16728958; Product type r: regulator; anti-sigma-YlaC factor YlaD 1544896 ylaD 935961 ylaD Bacillus subtilis subsp. subtilis str. 168 anti-sigma-YlaC factor YlaD NP_389357.1 1544603 D 224308 CDS NP_389358.1 16078539 935955 complement(1544936..1545547) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1545547 ylaE 935955 ylaE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389358.1 1544936 R 224308 CDS NP_389359.1 16078540 935954 complement(1545820..1546008) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1546008 ylaF 935954 ylaF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389359.1 1545820 R 224308 CDS NP_389360.1 16078541 935966 1546121..1547959 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11683274, 12399512, 9642082; Product type e : enzyme; GTP-binding protein TypA/BipA homolog 1547959 bipA 935966 bipA Bacillus subtilis subsp. subtilis str. 168 GTP-binding protein TypA/BipA homolog NP_389360.1 1546121 D 224308 CDS NP_389361.1 16078542 935937 1548016..1548333 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1548333 ylaH 935937 ylaH Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389361.1 1548016 D 224308 CDS NP_389362.1 16078543 935943 complement(1548389..1548598) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1548598 ylaI 935943 ylaI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389362.1 1548389 R 224308 CDS NP_389363.1 16078544 935926 complement(1548681..1549310) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 1549310 ylaJ 935926 ylaJ Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_389363.1 1548681 R 224308 CDS NP_389364.1 16078545 935933 1549465..1550793 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12762842; Product type pf : factor; hypothetical protein 1550793 ylaK 935933 ylaK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389364.1 1549465 D 224308 CDS NP_389365.1 16078546 935944 complement(1550797..1551282) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1551282 ylaL 935944 ylaL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389365.1 1550797 R 224308 CDS NP_389366.1 16078547 939852 1551385..1552314 1 NC_000964.3 catalyzes the formation of glutamate from glutamine; glutaminase 1552314 ylaM 939852 ylaM Bacillus subtilis subsp. subtilis str. 168 glutaminase NP_389366.1 1551385 D 224308 CDS NP_389367.1 16078548 936566 1552412..1552693 1 NC_000964.3 depletion of this protein in Bacillus subtilis results in defects in cell morphology; crystal structure of Staphylococcus protein shows homodimer; ligand binding protein; hypothetical protein 1552693 ylaN 936566 ylaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389367.1 1552412 D 224308 CDS NP_389368.1 16078549 935918 1552899..1554110 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12626683, 15849754, 16850406, 9622350; Product type t: transporter; lipid II flippase FtsW 1554110 ftsW 935918 ftsW Bacillus subtilis subsp. subtilis str. 168 lipid II flippase FtsW NP_389368.1 1552899 D 224308 CDS NP_389369.1 16078550 935920 1554185..1557631 1 NC_000964.3 biotin-containing enzyme that catalyzes a two step carboxylation of pyruvate to oxaloacetate; pyruvate carboxylase 1557631 pycA 935920 pycA Bacillus subtilis subsp. subtilis str. 168 pyruvate carboxylase NP_389369.1 1554185 D 224308 CDS NP_389370.1 16078551 937030 complement(1558034..1558954) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12206660, 15491161, 15849754, 16321940, 16850406; Product type e: enzyme; heme A synthase 1558954 ctaA 937030 ctaA Bacillus subtilis subsp. subtilis str. 168 heme A synthase NP_389370.1 1558034 R 224308 CDS NP_389371.1 16078552 935922 1559309..1560226 1 NC_000964.3 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 2 1560226 ctaB 935922 ctaB Bacillus subtilis subsp. subtilis str. 168 protoheme IX farnesyltransferase 2 NP_389371.1 1559309 D 224308 CDS NP_389372.1 16078553 936789 1560466..1561536 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1685007, 1847686, 9829923, 9882689; Product type e: enzyme; cytochrome c oxidase subunit 2 1561536 ctaC 936789 ctaC Bacillus subtilis subsp. subtilis str. 168 cytochrome c oxidase subunit 2 NP_389372.1 1560466 D 224308 CDS NP_389373.2 255767339 936898 1561569..1563437 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10675592, 15849754, 1685007, 16850406, 1847686; Product type e: enzyme; cytochrome c oxidase subunit 1 1563437 ctaD 936898 ctaD Bacillus subtilis subsp. subtilis str. 168 cytochrome c oxidase subunit 1 NP_389373.2 1561569 D 224308 CDS NP_389374.1 16078555 935993 1563437..1564060 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 1847686; Product type e: enzyme; cytochrome c oxidase subunit 3 1564060 ctaE 935993 ctaE Bacillus subtilis subsp. subtilis str. 168 cytochrome c oxidase subunit 3 NP_389374.1 1563437 D 224308 CDS NP_389375.1 16078556 936259 1564063..1564395 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1847686; Product type e : enzyme; cytochrome c oxidase subunit 4B 1564395 ctaF 936259 ctaF Bacillus subtilis subsp. subtilis str. 168 cytochrome c oxidase subunit 4B NP_389375.1 1564063 D 224308 CDS NP_389376.1 16078557 939909 1564422..1565315 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766920, 15849754, 16305244, 16850406; Product type f: factor; cytochrome c oxidase assembly factor CtaG 1565315 ctaG 939909 ctaG Bacillus subtilis subsp. subtilis str. 168 cytochrome c oxidase assembly factor CtaG NP_389376.1 1564422 D 224308 CDS NP_389377.1 16078558 939858 complement(1565347..1565709) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1565709 ylbA 939858 ylbA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389377.1 1565347 R 224308 CDS NP_389378.2 255767340 938107 1565849..1566295 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1566295 ylbB 938107 ylbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389378.2 1565849 D 224308 CDS NP_389379.1 16078560 937363 1566379..1567419 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1567419 ylbC 937363 ylbC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389379.1 1566379 D 224308 CDS NP_389380.1 16078561 936929 1567651..1568049 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1568049 ylbD 936929 ylbD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389380.1 1567651 D 224308 CDS NP_389381.1 16078562 938216 1568065..1568304 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1568304 ylbE 938216 ylbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389381.1 1568065 D 224308 CDS NP_389382.1 16078563 939945 1568420..1568869 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10712692, 15175311, 15661000; Product type pr: regulator; regulatory protein YlbF 1568869 ylbF 939945 ylbF Bacillus subtilis subsp. subtilis str. 168 regulatory protein YlbF NP_389382.1 1568420 D 224308 CDS NP_389383.1 16078564 939846 1568924..1569196 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1569196 ylbG 939846 ylbG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389383.1 1568924 D 224308 CDS NP_389384.2 255767341 936402 1569519..1570073 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; rRNA methyltransferase YlbH 1570073 ylbH 936402 ylbH Bacillus subtilis subsp. subtilis str. 168 rRNA methyltransferase YlbH NP_389384.2 1569519 D 224308 CDS NP_389385.1 16078566 936889 1570078..1570563 1 NC_000964.3 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 1570563 coaD 936889 coaD Bacillus subtilis subsp. subtilis str. 168 phosphopantetheine adenylyltransferase NP_389385.1 1570078 D 224308 CDS NP_389386.1 16078567 936629 complement(1570574..1571800) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type cp: cell process; sporulation integral membrane protein YlbJ 1571800 ylbJ 936629 ylbJ Bacillus subtilis subsp. subtilis str. 168 sporulation integral membrane protein YlbJ NP_389386.1 1570574 R 224308 CDS NP_389387.1 16078568 936382 1571981..1572763 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NTE family protein YlbK 1572763 ylbK 936382 ylbK Bacillus subtilis subsp. subtilis str. 168 NTE family protein YlbK NP_389387.1 1571981 D 224308 CDS NP_389388.2 255767342 936755 1572765..1573790 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1573790 ylbL 936755 ylbL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389388.2 1572765 D 224308 CDS NP_389389.1 16078570 936548 complement(1573807..1575054) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1575054 ylbM 936548 ylbM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389389.1 1573807 R 224308 CDS YP_003097727.1 255767343 8303049 complement(1575051..1575236) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1575236 ylzH 8303049 ylzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097727.1 1575051 R 224308 CDS NP_389390.1 16078571 936788 1575264..1575782 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11700356; hypothetical protein 1575782 ylbN 936788 ylbN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389390.1 1575264 D 224308 CDS NP_389391.1 16078572 939855 1575804..1575983 1 NC_000964.3 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 1575983 rpmF 939855 rpmF Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L32 NP_389391.1 1575804 D 224308 CDS NP_389392.1 16078573 935998 1576129..1576710 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15621419; Product type cp: cell process; hypothetical protein 1576710 ylbO 935998 ylbO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389392.1 1576129 D 224308 CDS NP_389393.2 255767344 939853 complement(1576767..1577249) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YlbP 1577249 ylbP 939853 ylbP Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YlbP NP_389393.2 1576767 R 224308 CDS NP_389394.1 16078575 936782 1577409..1578305 1 NC_000964.3 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis; 2-dehydropantoate 2-reductase 1578305 ylbQ 936782 ylbQ Bacillus subtilis subsp. subtilis str. 168 2-dehydropantoate 2-reductase NP_389394.1 1577409 D 224308 CDS NP_389395.2 255767345 939844 1578376..1579995 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16169927; Product type pf : factor; hypothetical protein 1579995 yllA 939844 yllA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389395.2 1578376 D 224308 CDS NP_389396.1 16078577 935932 1580121..1580552 1 NC_000964.3 MraZ; UPF0040; crystal structure shows similarity to AbrB; protein MraZ 1580552 yllB 935932 yllB Bacillus subtilis subsp. subtilis str. 168 protein MraZ NP_389396.1 1580121 D 224308 CDS NP_389397.1 16078578 936555 1580622..1581557 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10572301, 16849811; Product type e: enzyme; ribosomal RNA small subunit methyltransferase H 1581557 mraW 936555 mraW Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase H NP_389397.1 1580622 D 224308 CDS NP_389398.1 16078579 939860 1581597..1581950 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10792716, 10844672, 11994149, 16549676, 16936019, 17020588; Product type cp : cell process; cell division protein FtsL 1581950 ftsL 939860 ftsL Bacillus subtilis subsp. subtilis str. 168 cell division protein FtsL NP_389398.1 1581597 D 224308 CDS NP_389399.2 255767346 939847 1581947..1584097 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14731276, 8636036; Product type cp: cell process; penicillin-binding protein 2B 1584097 pbpB 939847 pbpB Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 2B NP_389399.2 1581947 D 224308 CDS NP_389400.2 255767347 936661 1584214..1586154 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8244929, 8289242, 9006059; Product type cp: cell process; stage V sporulation protein D 1586154 spoVD 936661 spoVD Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein D NP_389400.2 1584214 D 224308 CDS NP_389401.1 16078582 937567 1586330..1587814 1 NC_000964.3 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase 1587814 murE 937567 murE Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase NP_389401.1 1586330 D 224308 CDS NP_389402.2 255767348 939856 1587926..1588900 1 NC_000964.3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-n-acetylmuramoyl-pentapeptide- transferase 1588900 mraY 939856 mraY Bacillus subtilis subsp. subtilis str. 168 phospho-n-acetylmuramoyl-pentapeptide- transferase NP_389402.2 1587926 D 224308 CDS NP_389403.1 16078584 935950 1588901..1590256 1 NC_000964.3 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoylalanine--D-glutamate ligase 1590256 murD 935950 murD Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylmuramoylalanine--D-glutamate ligase NP_389403.1 1588901 D 224308 CDS NP_389404.1 16078585 936953 1590317..1591417 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16484183, 16850406, 2509435, 9622350; Product type cp: cell process; stage V sporulation protein E 1591417 spoVE 936953 spoVE Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein E NP_389404.1 1590317 D 224308 CDS NP_389405.2 255767349 935929 1591540..1592631 1 NC_000964.3 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1592631 murG 935929 murG Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase NP_389405.2 1591540 D 224308 CDS NP_389406.1 16078587 939804 1592663..1593574 1 NC_000964.3 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 1593574 murB 939804 murB Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylenolpyruvoylglucosamine reductase NP_389406.1 1592663 D 224308 CDS NP_389407.1 16078588 939701 1593704..1594495 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10852898, 12682299, 15659156, 16618922, 16936019, 16936026; Product type cp : cell process; cell division protein DivIB 1594495 divIB 939701 divIB Bacillus subtilis subsp. subtilis str. 168 cell division protein DivIB NP_389407.1 1593704 D 224308 CDS NP_389408.2 255767350 936403 1594492..1595187 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16484183; hypothetical protein 1595187 ylxW 936403 ylxW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389408.2 1594492 D 224308 CDS NP_389409.2 255767351 936107 1595210..1595917 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1595917 ylxX 936107 ylxX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389409.2 1595210 D 224308 CDS NP_389410.1 16078591 936141 1595935..1596300 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1569582, 15849754, 16850406; Product type pm: membrane component; small basic protein 1596300 sbp 936141 sbp Bacillus subtilis subsp. subtilis str. 168 small basic protein NP_389410.1 1595935 D 224308 CDS NP_389411.2 255767352 936145 1596474..1597796 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15153768, 16159787, 16796675, 17015652; Product type cp: cell process; cell division protein FtsA 1597796 ftsA 936145 ftsA Bacillus subtilis subsp. subtilis str. 168 cell division protein FtsA NP_389411.2 1596474 D 224308 CDS NP_389412.2 255767353 935971 1597832..1598980 1 NC_000964.3 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1598980 ftsZ 935971 ftsZ Bacillus subtilis subsp. subtilis str. 168 cell division protein FtsZ NP_389412.2 1597832 D 224308 CDS NP_389413.1 16078594 939695 1599283..1603584 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1368833, 15205417, 15375126, 1938892, 2106512; Product type e: enzyme; bacillopeptidase F 1603584 bpr 939695 bpr Bacillus subtilis subsp. subtilis str. 168 bacillopeptidase F NP_389413.1 1599283 D 224308 CDS NP_389414.1 16078595 939984 1603779..1604708 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498732, 15849754, 16850406, 7585939, 7729420, 9573195, 9663680; Product type e: enzyme; sporulation sigma-E factor-processing peptidase 1604708 spoIIGA 939984 spoIIGA Bacillus subtilis subsp. subtilis str. 168 sporulation sigma-E factor-processing peptidase NP_389414.1 1603779 D 224308 CDS NP_389415.2 255767354 939683 1604771..1605490 1 NC_000964.3 sigma-29; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the mother cell at the onset of sporulation; RNA polymerase sigma-E factor 1605490 sigE 939683 sigE Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-E factor NP_389415.2 1604771 D 224308 CDS NP_389416.1 16078597 939953 1605630..1606412 1 NC_000964.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed after engulfment; this factor is involved in the transcription of small acid-soluble proteins involved in protecting the forespore chromatin; RNA polymerase sigma-G factor 1606412 sigG 939953 sigG Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-G factor NP_389416.1 1605630 D 224308 CDS NP_389417.2 255767355 940012 1606560..1607354 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pt : transporter; ABC transporter ATP-binding protein 1607354 ylmA 940012 ylmA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_389417.2 1606560 D 224308 CDS NP_389418.2 255767356 940116 1607556..1608836 1 NC_000964.3 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; N-formyl-4-amino-5-aminomethyl-2- methylpyrimidine deformylase 1608836 ylmB 940116 ylmB Bacillus subtilis subsp. subtilis str. 168 N-formyl-4-amino-5-aminomethyl-2- methylpyrimidine deformylase NP_389418.2 1607556 D 224308 CDS NP_389419.1 16078600 939682 1608919..1609164 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060; hypothetical protein 1609164 ylmC 939682 ylmC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389419.1 1608919 D 224308 CDS NP_389420.1 16078601 939954 1609327..1610163 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; laccase domain protein YlmD 1610163 ylmD 939954 ylmD Bacillus subtilis subsp. subtilis str. 168 laccase domain protein YlmD NP_389420.1 1609327 D 224308 CDS NP_389421.1 16078602 940117 1610170..1610862 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14526035; hypothetical protein 1610862 ylmE 940117 ylmE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389421.1 1610170 D 224308 CDS NP_389422.2 255767357 939952 1610865..1611314 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526035, 16420366, 16796675, 18782755; Product type cp: cell process; cell division machinery factor 1611314 sepF 939952 sepF Bacillus subtilis subsp. subtilis str. 168 cell division machinery factor NP_389422.2 1610865 D 224308 CDS NP_389423.1 16078604 940008 1611321..1611593 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14526035; Product type f: factor; membrane protein 1611593 ylmG 940008 ylmG Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389423.1 1611321 D 224308 CDS NP_389424.1 16078605 940118 1611654..1612427 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10093218, 14526035; Product type f: factor; RNA-binding protein YlmH 1612427 ylmH 940118 ylmH Bacillus subtilis subsp. subtilis str. 168 RNA-binding protein YlmH NP_389424.1 1611654 D 224308 CDS NP_389425.1 16078606 939972 1612521..1613015 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950914, 14526035, 15165232, 15554965, 16885474; Product type f: factor; septum site-determining protein DivIVA 1613015 divIVA 939972 divIVA Bacillus subtilis subsp. subtilis str. 168 septum site-determining protein DivIVA NP_389425.1 1612521 D 224308 CDS NP_389426.2 255767358 940119 1613357..1616122 1 NC_000964.3 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase; some organisms carry two different copies of this enzyme; isoleucine--tRNA ligase 1616122 ileS 940119 ileS Bacillus subtilis subsp. subtilis str. 168 isoleucine--tRNA ligase NP_389426.2 1613357 D 224308 CDS NP_389427.2 255767359 938068 1616267..1616641 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987; hypothetical protein 1616641 ylyA 938068 ylyA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389427.2 1616267 D 224308 CDS NP_389428.1 16078609 938172 1616744..1617208 1 NC_000964.3 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 1617208 lspA 938172 lspA Bacillus subtilis subsp. subtilis str. 168 lipoprotein signal peptidase NP_389428.1 1616744 D 224308 CDS NP_389429.3 255767360 939987 1617210..1618121 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15078091, 15928344, 17188032; Product type e: enzyme; RNA pseudouridine synthase YlyB 1618121 rluD 939987 rluD Bacillus subtilis subsp. subtilis str. 168 RNA pseudouridine synthase YlyB NP_389429.3 1617210 D 224308 CDS NP_389430.1 16078611 938030 1618304..1618849 1 NC_000964.3 regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional protein PyrR 1618849 pyrR 938030 pyrR Bacillus subtilis subsp. subtilis str. 168 bifunctional protein PyrR NP_389430.1 1618304 D 224308 CDS NP_389431.2 255767361 936604 1619023..1620330 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8206848; Product type t : transporter; uracil permease 1620330 pyrP 936604 pyrP Bacillus subtilis subsp. subtilis str. 168 uracil permease NP_389431.2 1619023 D 224308 CDS NP_389432.2 255767362 937734 1620476..1621390 1 NC_000964.3 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase 1621390 pyrB 937734 pyrB Bacillus subtilis subsp. subtilis str. 168 aspartate carbamoyltransferase NP_389432.2 1620476 D 224308 CDS NP_389433.2 255767363 937095 1621374..1622660 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16522191, 7516791; Product type e: enzyme; dihydroorotase 1622660 pyrC 937095 pyrC Bacillus subtilis subsp. subtilis str. 168 dihydroorotase NP_389433.2 1621374 D 224308 CDS NP_389434.1 16078615 937368 1622657..1623751 1 NC_000964.3 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl-phosphate synthase pyrimidine-specific small chain 1623751 pyrAA 937368 pyrAA Bacillus subtilis subsp. subtilis str. 168 carbamoyl-phosphate synthase pyrimidine-specific small chain NP_389434.1 1622657 D 224308 CDS NP_389435.1 16078616 936608 1623736..1626951 1 NC_000964.3 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl-phosphate synthase pyrimidine-specific large chain 1626951 carB 936608 carB Bacillus subtilis subsp. subtilis str. 168 carbamoyl-phosphate synthase pyrimidine-specific large chain NP_389435.1 1623736 D 224308 CDS NP_389436.1 16078617 936854 1626948..1627718 1 NC_000964.3 responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase B 1627718 pyrK 936854 pyrK Bacillus subtilis subsp. subtilis str. 168 dihydroorotate dehydrogenase B NP_389436.1 1626948 D 224308 CDS NP_389437.1 16078618 938008 1627718..1628653 1 NC_000964.3 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase B 1628653 pyrD 938008 pyrD Bacillus subtilis subsp. subtilis str. 168 dihydroorotate dehydrogenase B NP_389437.1 1627718 D 224308 CDS NP_389438.1 16078619 935960 1628622..1629341 1 NC_000964.3 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 1629341 pyrF 935960 pyrF Bacillus subtilis subsp. subtilis str. 168 orotidine 5'-phosphate decarboxylase NP_389438.1 1628622 D 224308 CDS NP_389439.1 16078620 936714 1629320..1629970 1 NC_000964.3 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 1629970 pyrE 936714 pyrE Bacillus subtilis subsp. subtilis str. 168 orotate phosphoribosyltransferase NP_389439.1 1629320 D 224308 CDS NP_389440.1 16078621 938645 1630382..1631083 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12072441, 16267287, 11004190, 10094622; Product type e: enzyme; phosphoadenosine phosphosulfate reductase 1631083 cysH 938645 cysH Bacillus subtilis subsp. subtilis str. 168 phosphoadenosine phosphosulfate reductase NP_389440.1 1630382 D 224308 CDS NP_389441.1 16078622 935990 1631095..1632159 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10784039, 15849754, 16850406, 11004190, 10094622; Product type t : transporter; sulfate permease CysP 1632159 cysP 935990 cysP Bacillus subtilis subsp. subtilis str. 168 sulfate permease CysP NP_389441.1 1631095 D 224308 CDS NP_389442.1 16078623 936726 1632208..1633356 1 NC_000964.3 ATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; sulfate adenylyltransferase 1633356 sat 936726 sat Bacillus subtilis subsp. subtilis str. 168 sulfate adenylyltransferase NP_389442.1 1632208 D 224308 CDS NP_389443.1 16078624 937102 1633369..1633962 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1332767, 11004190, 10094622; Product type e : enzyme; adenylyl-sulfate kinase 1633962 cysC 937102 cysC Bacillus subtilis subsp. subtilis str. 168 adenylyl-sulfate kinase NP_389443.1 1633369 D 224308 CDS NP_389444.1 16078625 936712 1634061..1634834 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1906874, 11004190, 10094622; Product type e : enzyme; uroporphyrinogen-iii C-methyltransferase 1634834 sumT 936712 sumT Bacillus subtilis subsp. subtilis str. 168 uroporphyrinogen-iii C-methyltransferase NP_389444.1 1634061 D 224308 CDS NP_389445.1 16078626 936218 1634837..1635622 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme; sirohydrochlorin ferrochelatase 1635622 sirB 936218 sirB Bacillus subtilis subsp. subtilis str. 168 sirohydrochlorin ferrochelatase NP_389445.1 1634837 D 224308 CDS NP_389446.1 16078627 938048 1635603..1636091 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12408752, 11004190, 10094622; Product type e : enzyme; precorrin-2 dehydrogenase 1636091 sirC 938048 sirC Bacillus subtilis subsp. subtilis str. 168 precorrin-2 dehydrogenase NP_389446.1 1635603 D 224308 CDS NP_389447.1 16078628 936878 complement(1636131..1637849) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11238985, 17586671; Product type pf: factor; hypothetical protein 1637849 yloA 936878 yloA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389447.1 1636131 R 224308 CDS NP_389448.1 16078629 936954 1637965..1640637 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12161109; Product type t: transporter; calcium-transporting ATPase 1640637 yloB 936954 yloB Bacillus subtilis subsp. subtilis str. 168 calcium-transporting ATPase NP_389448.1 1637965 D 224308 CDS NP_389449.1 16078630 936454 1640720..1641595 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1641595 yloC 936454 yloC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389449.1 1640720 D 224308 CDS NP_570902.1 18677778 937956 1641672..1641941 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1641941 ylzA 937956 ylzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_570902.1 1641672 D 224308 CDS NP_389450.2 50812226 938821 1641949..1642563 1 NC_000964.3 Essential for recycling GMP and indirectly, cGMP; guanylate kinase 1642563 gmk 938821 gmk Bacillus subtilis subsp. subtilis str. 168 guanylate kinase NP_389450.2 1641949 D 224308 CDS NP_389451.1 16078632 936419 1642567..1642770 1 NC_000964.3 Promotes RNA polymerase assembly; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega 1642770 rpoZ 936419 rpoZ Bacillus subtilis subsp. subtilis str. 168 DNA-directed RNA polymerase subunit omega NP_389451.1 1642567 D 224308 CDS NP_389452.1 16078633 938487 1642851..1644071 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11278255, 11358972, 12140293, 14686929, 15530362; Product type e: enzyme; coenzyme A biosynthesis bifunctional protein CoaBC 1644071 coaBC 938487 coaBC Bacillus subtilis subsp. subtilis str. 168 coenzyme A biosynthesis bifunctional protein CoaBC NP_389452.1 1642851 D 224308 CDS NP_389453.1 16078634 938122 1644068..1646485 1 NC_000964.3 binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity; primosomal protein N' 1646485 priA 938122 priA Bacillus subtilis subsp. subtilis str. 168 primosomal protein N' NP_389453.1 1644068 D 224308 CDS NP_389454.1 16078635 938819 1646512..1646994 1 NC_000964.3 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1646994 def 938819 def Bacillus subtilis subsp. subtilis str. 168 peptide deformylase NP_389454.1 1646512 D 224308 CDS NP_389455.1 16078636 936571 1646999..1647952 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10858337, 9843487; Product type e: enzyme; methionyl-tRNA formyltransferase 1647952 fmt 936571 fmt Bacillus subtilis subsp. subtilis str. 168 methionyl-tRNA formyltransferase NP_389455.1 1646999 D 224308 CDS NP_389456.1 16078637 938106 1647939..1649282 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14656444; Product type e: enzyme; ribosomal RNA small subunit methyltransferase B 1649282 rsmB 938106 rsmB Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase B NP_389456.1 1647939 D 224308 CDS NP_389457.1 16078638 936310 1649286..1650377 1 NC_000964.3 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; dual-specificity RNA methyltransferase RlmN 1650377 yloN 936310 yloN Bacillus subtilis subsp. subtilis str. 168 dual-specificity RNA methyltransferase RlmN NP_389457.1 1649286 D 224308 CDS NP_389458.1 16078639 935931 1650384..1651148 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 10986276; Product type e: enzyme; protein phosphatase PrpC 1651148 prpC 935931 prpC Bacillus subtilis subsp. subtilis str. 168 protein phosphatase PrpC NP_389458.1 1650384 D 224308 CDS NP_389459.1 16078640 936132 1651142..1653088 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399479, 18984160, 10986276; Product type e: enzyme; serine/threonine protein kinase 1653088 prkC 936132 prkC Bacillus subtilis subsp. subtilis str. 168 serine/threonine protein kinase NP_389459.1 1651142 D 224308 CDS NP_389460.1 16078641 938451 1653103..1653999 1 NC_000964.3 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome biogenesis GTPase RsgA 1653999 yloQ 938451 yloQ Bacillus subtilis subsp. subtilis str. 168 ribosome biogenesis GTPase RsgA NP_389460.1 1653103 D 224308 CDS NP_389461.1 16078642 936393 1654004..1654657 1 NC_000964.3 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate; ribulose-phosphate 3-epimerase 1654657 rpe 936393 rpe Bacillus subtilis subsp. subtilis str. 168 ribulose-phosphate 3-epimerase NP_389461.1 1654004 D 224308 CDS NP_389462.1 16078643 937714 1654730..1655374 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15150256, 16291685; Product type e: enzyme; thiamine pyrophosphokinase 1655374 thiN 937714 thiN Bacillus subtilis subsp. subtilis str. 168 thiamine pyrophosphokinase NP_389462.1 1654730 D 224308 CDS NP_389463.1 16078644 937168 1655446..1655526 1 NC_000964.3 involved in the production of the spore cortex and coat; stage V sporulation protein M 1655526 spoVM 937168 spoVM Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein M NP_389463.1 1655446 D 224308 CDS NP_389464.1 16078645 938067 complement(1655599..1655787) 1 NC_000964.3 required for 70S ribosome assembly; 50S ribosomal protein L28 1655787 rpmB 938067 rpmB Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L28 NP_389464.1 1655599 R 224308 CDS NP_389465.1 16078646 937855 1656064..1656426 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1656426 yloU 937855 yloU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389465.1 1656064 D 224308 CDS NP_389466.1 16078647 937917 1656442..1658103 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16647083; Product type pe : enzyme; hypothetical protein 1658103 yloV 937917 yloV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389466.1 1656442 D 224308 CDS NP_389467.1 16078648 935964 1658242..1658904 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 8385012, 9244285; Product type e : enzyme; L-serine dehydratase, beta chain 1658904 sdaAB 935964 sdaAB Bacillus subtilis subsp. subtilis str. 168 L-serine dehydratase, beta chain NP_389467.1 1658242 D 224308 CDS NP_389468.1 16078649 937109 1658930..1659832 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 2504697; Product type e: enzyme; L-serine dehydratase, alpha chain 1659832 sdaAA 937109 sdaAA Bacillus subtilis subsp. subtilis str. 168 L-serine dehydratase, alpha chain NP_389468.1 1658930 D 224308 CDS NP_389469.1 16078650 936730 1659810..1661858 1 NC_000964.3 catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG 1661858 recG 936730 recG Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA helicase RecG NP_389469.1 1659810 D 224308 CDS NP_389470.1 16078651 936595 1661967..1662533 1 NC_000964.3 negative regulator of genes involved in fatty acid and phospholipid biosynthesis for gram positive bacteria; transcription factor FapR 1662533 ylpC 936595 ylpC Bacillus subtilis subsp. subtilis str. 168 transcription factor FapR NP_389470.1 1661967 D 224308 CDS NP_389471.1 16078652 938066 1662547..1663548 1 NC_000964.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; phosphate acyltransferase 1663548 plsX 938066 plsX Bacillus subtilis subsp. subtilis str. 168 phosphate acyltransferase NP_389471.1 1662547 D 224308 CDS NP_389472.1 16078653 938488 1663567..1664520 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14586097; Product type e: enzyme; malonyl CoA-acyl carrier protein transacylase 1664520 fabD 938488 fabD Bacillus subtilis subsp. subtilis str. 168 malonyl CoA-acyl carrier protein transacylase NP_389472.1 1663567 D 224308 CDS NP_389473.1 16078654 938113 1664513..1665253 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12655455, 12682299, 8759840; Product type e: enzyme; 3-oxoacyl-[acyl-carrier-protein] reductase FabG 1665253 fabG 938113 fabG Bacillus subtilis subsp. subtilis str. 168 3-oxoacyl-[acyl-carrier-protein] reductase FabG NP_389473.1 1664513 D 224308 CDS NP_389474.1 16078655 938486 1665337..1665570 1 NC_000964.3 carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 1665570 acpP 938486 acpP Bacillus subtilis subsp. subtilis str. 168 acyl carrier protein NP_389474.1 1665337 D 224308 CDS NP_389475.1 16078656 936169 1665710..1666459 1 NC_000964.3 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease 3 1666459 rnc 936169 rnc Bacillus subtilis subsp. subtilis str. 168 ribonuclease 3 NP_389475.1 1665710 D 224308 CDS NP_389476.2 255767364 938085 1666560..1670120 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137, 15987505, 16272394, 9701812; Product type e : enzyme; chromosome partition protein Smc 1670120 smc 938085 smc Bacillus subtilis subsp. subtilis str. 168 chromosome partition protein Smc NP_389476.2 1666560 D 224308 CDS NP_389477.1 16078658 936921 1670140..1671129 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15995216, 16705751, 11021934, 11123669, 11166993; Product type rc : receptor; signal recognition particle receptor FtsY 1671129 ftsY 936921 ftsY Bacillus subtilis subsp. subtilis str. 168 signal recognition particle receptor FtsY NP_389477.1 1670140 D 224308 CDS NP_389478.1 16078659 938179 complement(1671166..1671651) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 1671651 ylqB 938179 ylqB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389478.1 1671166 R 224308 CDS NP_389479.1 16078660 937995 1671828..1672160 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11274114; hypothetical protein 1672160 ylxM 937995 ylxM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389479.1 1671828 D 224308 CDS NP_389480.1 16078661 937104 1672174..1673514 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 10658653, 11123669, 7511896, 8662730, 10222262, 10224127; Product type cp: cell process; signal recognition particle protein 1673514 ffh 937104 ffh Bacillus subtilis subsp. subtilis str. 168 signal recognition particle protein NP_389480.1 1672174 D 224308 CDS NP_389481.1 16078662 938059 1673620..1673892 1 NC_000964.3 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 1673892 rpsP 938059 rpsP Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S16 NP_389481.1 1673620 D 224308 CDS NP_389482.1 16078663 936821 1673892..1674137 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1674137 ylqC 936821 ylqC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389482.1 1673892 D 224308 CDS NP_389483.1 16078664 937226 1674259..1674645 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1674645 ylqD 937226 ylqD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389483.1 1674259 D 224308 CDS NP_389484.1 16078665 935999 1674650..1675174 1 NC_000964.3 Essential for efficient processing of 16S rRNA; ribosome maturation factor RimM 1675174 rimM 935999 rimM Bacillus subtilis subsp. subtilis str. 168 ribosome maturation factor RimM NP_389484.1 1674650 D 224308 CDS NP_389485.1 16078666 936650 1675171..1675902 1 NC_000964.3 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1675902 trmD 936650 trmD Bacillus subtilis subsp. subtilis str. 168 tRNA (guanine-N(1)-)-methyltransferase NP_389485.1 1675171 D 224308 CDS NP_389486.1 16078667 937598 1676033..1676389 1 NC_000964.3 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1676389 rplS 937598 rplS Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L19 NP_389486.1 1676033 D 224308 CDS NP_389487.1 16078668 940134 1676532..1677380 1 NC_000964.3 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosome biogenesis GTPase A 1677380 rbgA 940134 rbgA Bacillus subtilis subsp. subtilis str. 168 ribosome biogenesis GTPase A NP_389487.1 1676532 D 224308 CDS NP_389488.1 16078669 940133 1677451..1678218 1 NC_000964.3 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII 1678218 rnhB 940133 rnhB Bacillus subtilis subsp. subtilis str. 168 ribonuclease HII NP_389488.1 1677451 D 224308 CDS NP_389489.1 16078670 936698 1678250..1679980 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1679980 ylqG 936698 ylqG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389489.1 1678250 D 224308 CDS NP_389490.1 16078671 938163 1679977..1680258 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 1680258 ylqH 938163 ylqH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389490.1 1679977 D 224308 CDS NP_389491.1 16078672 938521 1680431..1681588 1 NC_000964.3 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA ligase [ADP-forming] subunit beta 1681588 sucC 938521 sucC Bacillus subtilis subsp. subtilis str. 168 succinyl-CoA ligase [ADP-forming] subunit beta NP_389491.1 1680431 D 224308 CDS NP_389492.1 16078673 937797 1681617..1682519 1 NC_000964.3 Catalyzes the only substrate-level phosphorylation in the TCA cycle; succinyl-CoA ligase [ADP-forming] subunit alpha 1682519 sucD 937797 sucD Bacillus subtilis subsp. subtilis str. 168 succinyl-CoA ligase [ADP-forming] subunit alpha NP_389492.1 1681617 D 224308 CDS NP_389493.1 16078674 940135 1682580..1683473 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 16014871, 16978360, 17803906, 18045469, 7768823; Product type f: factor; protein smf 1683473 dprA 940135 dprA Bacillus subtilis subsp. subtilis str. 168 protein smf NP_389493.1 1682580 D 224308 CDS NP_389494.1 16078675 937982 1683661..1685736 1 NC_000964.3 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase 1 1685736 topA 937982 topA Bacillus subtilis subsp. subtilis str. 168 DNA topoisomerase 1 NP_389494.1 1683661 D 224308 CDS NP_389495.1 16078676 938816 1685812..1687119 1 NC_000964.3 TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO 1687119 gid 938816 gid Bacillus subtilis subsp. subtilis str. 168 methylenetetrahydrofolate--tRNA-(uracil-5-)- methyltransferase TrmFO NP_389495.1 1685812 D 224308 CDS NP_389496.1 16078677 938003 1687187..1688101 1 NC_000964.3 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; tyrosine recombinase XerC 1688101 xerC 938003 xerC Bacillus subtilis subsp. subtilis str. 168 tyrosine recombinase XerC NP_389496.1 1687187 D 224308 CDS NP_389497.1 16078678 938111 1688114..1688659 1 NC_000964.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease subunit ClpQ 1688659 clpQ 938111 clpQ Bacillus subtilis subsp. subtilis str. 168 ATP-dependent protease subunit ClpQ NP_389497.1 1688114 D 224308 CDS NP_389498.1 16078679 936301 1688676..1690079 1 NC_000964.3 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATPase subunit ClpY 1690079 hslU 936301 hslU Bacillus subtilis subsp. subtilis str. 168 ATP-dependent protease ATPase subunit ClpY NP_389498.1 1688676 D 224308 CDS NP_389499.1 16078680 936491 1690119..1690898 1 NC_000964.3 CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; GTP-sensing transcriptional pleiotropic repressor CodY 1690898 codY 936491 codY Bacillus subtilis subsp. subtilis str. 168 GTP-sensing transcriptional pleiotropic repressor CodY NP_389499.1 1690119 D 224308 CDS NP_389500.1 16078681 938149 1691278..1691667 1 NC_000964.3 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella; flagellar basal body rod protein FlgB 1691667 flgB 938149 flgB Bacillus subtilis subsp. subtilis str. 168 flagellar basal body rod protein FlgB NP_389500.1 1691278 D 224308 CDS NP_389501.1 16078682 938646 1691667..1692119 1 NC_000964.3 with FlgF and B makes up the proximal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgC 1692119 flgC 938646 flgC Bacillus subtilis subsp. subtilis str. 168 flagellar basal-body rod protein FlgC NP_389501.1 1691667 D 224308 CDS NP_389502.1 16078683 939470 1692130..1692450 1 NC_000964.3 forms a junction between the M-ring and FlgB during flagella biosynthesis; flagellar hook-basal body complex protein FliE 1692450 fliE 939470 fliE Bacillus subtilis subsp. subtilis str. 168 flagellar hook-basal body complex protein FliE NP_389502.1 1692130 D 224308 CDS NP_389503.1 16078684 936677 1692496..1694106 1 NC_000964.3 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod; flagellar M-ring protein 1694106 fliF 936677 fliF Bacillus subtilis subsp. subtilis str. 168 flagellar M-ring protein NP_389503.1 1692496 D 224308 CDS NP_389504.1 16078685 937577 1694119..1695135 1 NC_000964.3 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch protein FliG 1695135 fliG 937577 fliG Bacillus subtilis subsp. subtilis str. 168 flagellar motor switch protein FliG NP_389504.1 1694119 D 224308 CDS NP_389505.2 255767365 938124 1695254..1695880 1 NC_000964.3 binds to and inhibits the function of flagella specific ATPase FliI; flagellar assembly protein FliH 1695880 fliH 938124 fliH Bacillus subtilis subsp. subtilis str. 168 flagellar assembly protein FliH NP_389505.2 1695254 D 224308 CDS NP_389506.2 255767366 940136 1695877..1697193 1 NC_000964.3 involved in type III protein export during flagellum assembly; flagellum-specific ATP synthase 1697193 fliI 940136 fliI Bacillus subtilis subsp. subtilis str. 168 flagellum-specific ATP synthase NP_389506.2 1695877 D 224308 CDS NP_389507.1 16078688 940137 1697196..1697639 1 NC_000964.3 rod/hook and filament chaperone; flagellar FliJ protein 1697639 fliJ 940137 fliJ Bacillus subtilis subsp. subtilis str. 168 flagellar FliJ protein NP_389507.1 1697196 D 224308 CDS NP_389508.2 255767367 940140 1697651..1698265 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; FlaA locus 22.9 kDa protein 1698265 ylxF 940140 ylxF Bacillus subtilis subsp. subtilis str. 168 FlaA locus 22.9 kDa protein NP_389508.2 1697651 D 224308 CDS NP_389509.2 255767368 937494 1698278..1699741 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16630628, 16949608; Product type f: factor; flagellar hook-length control protein 1699741 fliK 937494 fliK Bacillus subtilis subsp. subtilis str. 168 flagellar hook-length control protein NP_389509.2 1698278 D 224308 CDS NP_389510.1 16078691 936501 1699738..1700160 1 NC_000964.3 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; FlaA locus hypothetical protein YlxG 1700160 flgD 936501 flgD Bacillus subtilis subsp. subtilis str. 168 FlaA locus hypothetical protein YlxG NP_389510.1 1699738 D 224308 CDS NP_389511.2 255767369 936497 1700182..1700976 1 NC_000964.3 makes up the distal portion of the flagellar basal body rod; flagellar basal-body rod protein FlgG 1700976 flgG 936497 flgG Bacillus subtilis subsp. subtilis str. 168 flagellar basal-body rod protein FlgG NP_389511.2 1700182 D 224308 CDS YP_003097728.1 255767370 8303013 1701016..1701231 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 1701231 ylzI 8303013 ylzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097728.1 1701016 D 224308 CDS NP_389512.1 16078693 937103 1701228..1701650 1 NC_000964.3 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring; flagellar protein FliL 1701650 fliL 937103 fliL Bacillus subtilis subsp. subtilis str. 168 flagellar protein FliL NP_389512.1 1701228 D 224308 CDS NP_389513.1 16078694 939518 1701684..1702682 1 NC_000964.3 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation; flagellar motor switch protein FliM 1702682 fliM 939518 fliM Bacillus subtilis subsp. subtilis str. 168 flagellar motor switch protein FliM NP_389513.1 1701684 D 224308 CDS NP_389514.1 16078695 936421 1702672..1703808 1 NC_000964.3 One of three proteins involved in switching the direction of the flagellar rotation; flagellar motor switch phosphatase FliY 1703808 fliY 936421 fliY Bacillus subtilis subsp. subtilis str. 168 flagellar motor switch phosphatase FliY NP_389514.1 1702672 D 224308 CDS NP_389515.1 16078696 940120 1703834..1704196 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 12864845, 12920116, 14749334; Product type r: regulator; chemotaxis protein CheY 1704196 cheY 940120 cheY Bacillus subtilis subsp. subtilis str. 168 chemotaxis protein CheY NP_389515.1 1703834 D 224308 CDS NP_389516.1 16078697 936796 1704211..1704870 1 NC_000964.3 possible structural component of the flagellum that anchors the rod to the membrane; flagellar biosynthetic protein FliZ 1704870 fliZ 936796 fliZ Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthetic protein FliZ NP_389516.1 1704211 D 224308 CDS NP_389517.1 16078698 940095 1704863..1705528 1 NC_000964.3 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliP 1705528 fliP 940095 fliP Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthetic protein FliP NP_389517.1 1704863 D 224308 CDS NP_389518.1 16078699 939623 1705543..1705812 1 NC_000964.3 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliQ 1705812 fliQ 939623 fliQ Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthetic protein FliQ NP_389518.1 1705543 D 224308 CDS NP_389519.2 255767371 940130 1705820..1706599 1 NC_000964.3 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus; flagellar biosynthetic protein FliR 1706599 fliR 940130 fliR Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthetic protein FliR NP_389519.2 1705820 D 224308 CDS NP_389520.1 16078701 940128 1706599..1707681 1 NC_000964.3 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export; flagellar biosynthetic protein FlhB 1707681 flhB 940128 flhB Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthetic protein FlhB NP_389520.1 1706599 D 224308 CDS NP_389521.2 255767372 940029 1707714..1709747 1 NC_000964.3 membrane protein involved in the flagellar export apparatus; flagellar biosynthesis protein FlhA 1709747 flhA 940029 flhA Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthesis protein FlhA NP_389521.2 1707714 D 224308 CDS NP_389522.1 16078703 940021 1709747..1710847 1 NC_000964.3 positive regulator of class III flagellar genes; flagellar biosynthesis protein FlhF 1710847 flhF 940021 flhF Bacillus subtilis subsp. subtilis str. 168 flagellar biosynthesis protein FlhF NP_389522.1 1709747 D 224308 CDS NP_389523.1 16078704 940123 1710838..1711734 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15361076; Product type f: factor; flagellum site-determining protein YlxH 1711734 ylxH 940123 ylxH Bacillus subtilis subsp. subtilis str. 168 flagellum site-determining protein YlxH NP_389523.1 1710838 D 224308 CDS NP_389524.2 255767373 940124 1711736..1712809 1 NC_000964.3 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins; chemotaxis response regulator protein-glutamate methylesterase 1712809 cheB 940124 cheB Bacillus subtilis subsp. subtilis str. 168 chemotaxis response regulator protein-glutamate methylesterase NP_389524.2 1711736 D 224308 CDS NP_389525.2 255767374 939600 1712815..1714833 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12094812, 12864845, 12920116, 15451661, 16045621; Product type rc: receptor; chemotaxis protein CheA 1714833 cheA 939600 cheA Bacillus subtilis subsp. subtilis str. 168 chemotaxis protein CheA NP_389525.2 1712815 D 224308 CDS NP_389526.1 16078707 939957 1714855..1715325 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12864845, 15451661, 1624415, 8169223, 8169224; Product type r: regulator; chemotaxis protein CheW 1715325 cheW 939957 cheW Bacillus subtilis subsp. subtilis str. 168 chemotaxis protein CheW NP_389526.1 1714855 D 224308 CDS NP_389527.1 16078708 939621 1715344..1715973 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12920116, 14749334, 14993307, 15546616, 16469702; Product type cp: cell process; Chey-P phosphatase CheC 1715973 cheC 939621 cheC Bacillus subtilis subsp. subtilis str. 168 Chey-P phosphatase CheC NP_389527.1 1715344 D 224308 CDS NP_389528.1 16078709 939959 1715970..1716470 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15546616, 16469702; Product type cp: cell process; chemoreceptor glutamine deamidase CheD 1716470 cheD 939959 cheD Bacillus subtilis subsp. subtilis str. 168 chemoreceptor glutamine deamidase CheD NP_389528.1 1715970 D 224308 CDS NP_389529.1 16078710 938482 1716493..1717257 1 NC_000964.3 expressed in late exponential phase; controls the expression of genes coding cell surface proteins involved in chemotaxis, flagellar assembly, and autolysis; RNA polymerase sigma-D factor 1717257 sigD 938482 sigD Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-D factor NP_389529.1 1716493 D 224308 CDS NP_389530.1 16078711 939618 1717286..1717789 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15066026, 15175317; Product type r: regulator; swarming motility protein SwrB 1717789 ylxL 939618 ylxL Bacillus subtilis subsp. subtilis str. 168 swarming motility protein SwrB NP_389530.1 1717286 D 224308 CDS NP_389531.1 16078712 939599 1717933..1718673 1 NC_000964.3 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 1718673 rpsB 939599 rpsB Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S2 NP_389531.1 1717933 D 224308 CDS NP_389532.1 16078713 939601 1718775..1719656 1 NC_000964.3 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 1719656 tsf 939601 tsf Bacillus subtilis subsp. subtilis str. 168 elongation factor Ts NP_389532.1 1718775 D 224308 CDS NP_389533.2 50812227 939602 1719802..1720524 1 NC_000964.3 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 1720524 pyrH 939602 pyrH Bacillus subtilis subsp. subtilis str. 168 uridylate kinase NP_389533.2 1719802 D 224308 CDS NP_389534.1 16078715 939605 1720526..1721083 1 NC_000964.3 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome-recycling factor 1721083 frr 939605 frr Bacillus subtilis subsp. subtilis str. 168 ribosome-recycling factor NP_389534.1 1720526 D 224308 CDS NP_389535.1 16078716 939640 1721214..1721996 1 NC_000964.3 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 1721996 uppS 939640 uppS Bacillus subtilis subsp. subtilis str. 168 undecaprenyl pyrophosphate synthase NP_389535.1 1721214 D 224308 CDS NP_389536.1 16078717 939607 1722000..1722809 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406; Product type e : enzyme; phosphatidate cytidylyltransferase 1722809 cdsA 939607 cdsA Bacillus subtilis subsp. subtilis str. 168 phosphatidate cytidylyltransferase NP_389536.1 1722000 D 224308 CDS NP_389537.2 255767375 939636 1722871..1724022 1 NC_000964.3 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1724022 dxr 939636 dxr Bacillus subtilis subsp. subtilis str. 168 1-deoxy-D-xylulose 5-phosphate reductoisomerase NP_389537.2 1722871 D 224308 CDS NP_389538.1 16078719 939612 1724029..1725297 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15130127, 15496982, 15520285, 16014871, 16899079; Product type e: enzyme; zinc metalloprotease RasP 1725297 rseP 939612 rseP Bacillus subtilis subsp. subtilis str. 168 zinc metalloprotease RasP NP_389538.1 1724029 D 224308 CDS NP_389539.1 16078720 939617 1725330..1727024 1 NC_000964.3 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); proline--tRNA ligase 1727024 proS 939617 proS Bacillus subtilis subsp. subtilis str. 168 proline--tRNA ligase NP_389539.1 1725330 D 224308 CDS NP_389540.1 16078721 939620 1727133..1731446 1 NC_000964.3 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC-type 1731446 polC 939620 polC Bacillus subtilis subsp. subtilis str. 168 DNA polymerase III PolC-type NP_389540.1 1727133 D 224308 CDS NP_389541.1 16078722 939625 1731776..1732246 1 NC_000964.3 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; ribosome maturation factor RimP 1732246 ylxS 939625 ylxS Bacillus subtilis subsp. subtilis str. 168 ribosome maturation factor RimP NP_389541.1 1731776 D 224308 CDS NP_389542.1 16078723 939628 1732281..1733396 1 NC_000964.3 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription termination/antitermination protein NusA 1733396 nusA 939628 nusA Bacillus subtilis subsp. subtilis str. 168 transcription termination/antitermination protein NusA NP_389542.1 1732281 D 224308 CDS NP_389543.1 16078724 939653 1733410..1733685 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11679764, 12682299; Product type pf: factor; hypothetical protein 1733685 ylxR 939653 ylxR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389543.1 1733410 D 224308 CDS NP_389544.1 16078725 939626 1733687..1733989 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15130481, 15361074; Product type f : factor; ribosomal protein YlxQ 1733989 ylxQ 939626 ylxQ Bacillus subtilis subsp. subtilis str. 168 ribosomal protein YlxQ NP_389544.1 1733687 D 224308 CDS NP_389545.1 16078726 939630 1734009..1736159 1 NC_000964.3 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 1736159 infB 939630 infB Bacillus subtilis subsp. subtilis str. 168 translation initiation factor IF-2 NP_389545.1 1734009 D 224308 CDS NP_389546.1 16078727 939641 1736156..1736434 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1736434 ylxP 939641 ylxP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389546.1 1736156 D 224308 CDS NP_389547.1 16078728 939635 1736451..1736804 1 NC_000964.3 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 1736804 rbfA 939635 rbfA Bacillus subtilis subsp. subtilis str. 168 ribosome-binding factor A NP_389547.1 1736451 D 224308 CDS NP_389548.1 16078729 939638 1736886..1737815 1 NC_000964.3 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1737815 truB 939638 truB Bacillus subtilis subsp. subtilis str. 168 tRNA pseudouridine synthase B NP_389548.1 1736886 D 224308 CDS NP_389549.1 16078730 938110 1737834..1738784 1 NC_000964.3 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; riboflavin biosynthesis protein RibC 1738784 ribC 938110 ribC Bacillus subtilis subsp. subtilis str. 168 riboflavin biosynthesis protein RibC NP_389549.1 1737834 D 224308 CDS NP_389550.1 16078731 938814 1738941..1739210 1 NC_000964.3 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 1739210 rpsO 938814 rpsO Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S15 NP_389550.1 1738941 D 224308 CDS NP_389551.1 16078732 939646 1739383..1741500 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572137, 15805522, 8636041, 8825779, 9179491; Product type e: enzyme; polyribonucleotide nucleotidyltransferase 1741500 pnpA 939646 pnpA Bacillus subtilis subsp. subtilis str. 168 polyribonucleotide nucleotidyltransferase NP_389551.1 1739383 D 224308 CDS NP_389552.1 16078733 939649 1741618..1742577 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14679227; Product type pe : enzyme; hypothetical protein 1742577 ylxY 939649 ylxY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389552.1 1741618 D 224308 CDS NP_389553.2 255767376 938456 1742617..1743846 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10666719, 10974125; Product type e: enzyme; zinc protease YmxG 1743846 mlpA 938456 mlpA Bacillus subtilis subsp. subtilis str. 168 zinc protease YmxG NP_389553.2 1742617 D 224308 CDS NP_389554.1 16078735 939648 1743924..1744181 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1744181 ymxH 939648 ymxH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389554.1 1743924 D 224308 CDS NP_389555.1 16078736 939652 1744367..1745260 1 NC_000964.3 catalyzes the synthesis of dipicolinic acid from dihydroxydipicolinic acid; plays a role in spore heat resistance; dipicolinate synthase subunit A 1745260 spoVFA 939652 spoVFA Bacillus subtilis subsp. subtilis str. 168 dipicolinate synthase subunit A NP_389555.1 1744367 D 224308 CDS NP_389556.1 16078737 939660 1745263..1745865 1 NC_000964.3 involved in production of dipicolinic acid (pyridine-2,6-dicarboxylic acid, DPA) which is synthesized late in sporulation in the mother cell and accumulates in the spore; mutations in this gene result in a lack of DPA synthesis; presumably functions with SpoVFA to form the synthase enzyme; dipicolinate synthase subunit B 1745865 spoVFB 939660 spoVFB Bacillus subtilis subsp. subtilis str. 168 dipicolinate synthase subunit B NP_389556.1 1745263 D 224308 CDS NP_389557.1 16078738 939654 1745991..1747031 1 NC_000964.3 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 1747031 asd 939654 asd Bacillus subtilis subsp. subtilis str. 168 aspartate-semialdehyde dehydrogenase NP_389557.1 1745991 D 224308 CDS NP_389558.2 255767377 936710 1747123..1748337 1 NC_000964.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; diaminopimelate sensitive; aspartokinase 1 1748337 dapG 936710 dapG Bacillus subtilis subsp. subtilis str. 168 aspartokinase 1 NP_389558.2 1747123 D 224308 CDS NP_389559.1 16078740 939657 1748368..1749240 1 NC_000964.3 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; 4-hydroxy-tetrahydrodipicolinate synthase 1749240 dapA 939657 dapA Bacillus subtilis subsp. subtilis str. 168 4-hydroxy-tetrahydrodipicolinate synthase NP_389559.1 1748368 D 224308 CDS NP_389560.2 255767378 938463 1749418..1751085 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15831787, 18713320; Product type e: enzyme; ribonuclease J 2 1751085 rnjB 938463 rnjB Bacillus subtilis subsp. subtilis str. 168 ribonuclease J 2 NP_389560.2 1749418 D 224308 CDS NP_389561.3 255767379 936370 1751201..1751938 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 15189290; Product type f: factor; translocation-enhancing protein TepA 1751938 tepA 936370 tepA Bacillus subtilis subsp. subtilis str. 168 translocation-enhancing protein TepA NP_389561.3 1751201 D 224308 CDS YP_003097729.1 255767380 8303181 1751935..1752147 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1752147 ylzJ 8303181 ylzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097729.1 1751935 D 224308 CDS NP_389562.2 255767381 936503 1752272..1754641 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11062134, 11778051, 12618465, 16430687, 17139259, 17322320, 18160039; Product type cp: cell process; spore DNA translocase 1754641 spoIIIE 936503 spoIIIE Bacillus subtilis subsp. subtilis str. 168 spore DNA translocase NP_389562.2 1752272 D 224308 CDS NP_389563.1 16078744 940138 1754785..1755510 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; GntR family transcriptional regulator 1755510 ymfC 940138 ymfC Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_389563.1 1754785 D 224308 CDS NP_389564.2 255767382 939662 1755649..1756857 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; bacillibactin exporter 1756857 ymfD 939662 ymfD Bacillus subtilis subsp. subtilis str. 168 bacillibactin exporter NP_389564.2 1755649 D 224308 CDS NP_389566.2 255767383 940141 1757037..1758317 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; inactive metalloprotease YmfF 1758317 ymfF 940141 ymfF Bacillus subtilis subsp. subtilis str. 168 inactive metalloprotease YmfF NP_389566.2 1757037 D 224308 CDS NP_389568.2 255767384 939665 1758314..1759600 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; zinc protease YmfH 1759600 ymfH 939665 ymfH Bacillus subtilis subsp. subtilis str. 168 zinc protease YmfH NP_389568.2 1758314 D 224308 CDS NP_389569.2 255767385 939588 1759655..1760383 1 NC_000964.3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 1760383 fabG 939588 fabG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389569.2 1759655 D 224308 CDS NP_389570.1 16078751 939670 1760464..1760721 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1760721 ymfJ 939670 ymfJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389570.1 1760464 D 224308 CDS NP_389573.3 255767386 939591 1761707..1762573 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12682299; membrane protein 1762573 ymfM 939591 ymfM Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389573.3 1761707 D 224308 CDS NP_389574.2 255767387 939675 1762623..1763204 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15743965, 15849754, 16514141, 16850406; Product type e: enzyme; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1763204 pgsA 939675 pgsA Bacillus subtilis subsp. subtilis str. 168 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase NP_389574.2 1762623 D 224308 CDS NP_389575.2 255767388 939464 1763222..1764472 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10438773, 11703670; Product type r : regulator; competence-damage inducible protein 1764472 cinA 939464 cinA Bacillus subtilis subsp. subtilis str. 168 competence-damage inducible protein NP_389575.2 1763222 D 224308 CDS NP_389576.2 255767389 939497 1764645..1765691 1 NC_000964.3 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase RecA 1765691 recA 939497 recA Bacillus subtilis subsp. subtilis str. 168 recombinase RecA NP_389576.2 1764645 D 224308 CDS NP_389577.1 16078758 939677 1765859..1767034 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762009, 15758244; Product type e: enzyme; penicillin-binding protein PbpX 1767034 pbpX 939677 pbpX Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein PbpX NP_389577.1 1765859 D 224308 CDS NP_389578.1 16078759 939680 1767310..1768872 1 NC_000964.3 protein from Staphylococcus aureus has phosphodiesterase activity against 2'-3'-cAMP and 2'-3'-cGMP; ribonuclease Y 1768872 ymdA 939680 ymdA Bacillus subtilis subsp. subtilis str. 168 ribonuclease Y NP_389578.1 1767310 D 224308 CDS NP_389579.2 255767390 939441 1768941..1769735 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1769735 ymdB 939441 ymdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389579.2 1768941 D 224308 CDS NP_389580.1 16078761 939460 1769935..1770195 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16428420, 7559352; Product type r: regulator; stage V sporulation protein S 1770195 spoVS 939460 spoVS Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein S NP_389580.1 1769935 D 224308 CDS NP_389581.1 16078762 939462 1770461..1771504 1 NC_000964.3 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism; L-threonine 3-dehydrogenase 1771504 tdh 939462 tdh Bacillus subtilis subsp. subtilis str. 168 L-threonine 3-dehydrogenase NP_389581.1 1770461 D 224308 CDS NP_389582.1 16078763 939651 1771517..1772695 1 NC_000964.3 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine; 2-amino-3-ketobutyrate CoA ligase 1772695 kbl 939651 kbl Bacillus subtilis subsp. subtilis str. 168 2-amino-3-ketobutyrate CoA ligase NP_389582.1 1771517 D 224308 CDS NP_389583.1 16078764 939451 1772843..1774372 1 NC_000964.3 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A); (dimethylallyl)adenosine tRNA methylthiotransferase MiaB 1774372 ymcB 939451 ymcB Bacillus subtilis subsp. subtilis str. 168 (dimethylallyl)adenosine tRNA methylthiotransferase MiaB NP_389583.1 1772843 D 224308 CDS NP_389584.1 16078765 939581 1774374..1774805 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000; Product type r: regulator; hypothetical protein 1774805 ymcA 939581 ymcA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389584.1 1774374 D 224308 CDS NP_389585.1 16078766 939508 1775067..1775612 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14563859, 14973022, 17172339; Product type cp: cell process; spore coat protein E 1775612 cotE 939508 cotE Bacillus subtilis subsp. subtilis str. 168 spore coat protein E NP_389585.1 1775067 D 224308 CDS NP_389586.2 255767391 939501 1775745..1778321 1 NC_000964.3 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 1778321 mutS 939501 mutS Bacillus subtilis subsp. subtilis str. 168 DNA mismatch repair protein MutS NP_389586.2 1775745 D 224308 CDS NP_389587.1 16078768 939455 1778337..1780220 1 NC_000964.3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein MutL 1780220 mutL 939455 mutL Bacillus subtilis subsp. subtilis str. 168 DNA mismatch repair protein MutL NP_389587.1 1778337 D 224308 CDS YP_054578.1 50812231 2914256 complement(1780618..1781073) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1781073 ymzD 2914256 ymzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054578.1 1780618 R 224308 CDS NP_389588.1 16078769 939511 complement(1781228..1781785) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1781785 ymcC 939511 ymcC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389588.1 1781228 R 224308 CDS NP_389589.1 16078770 939593 1781906..1782523 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 1782523 pksA 939593 pksA Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_389589.1 1781906 D 224308 CDS NP_389590.1 16078771 939445 1782713..1783390 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polyketide biosynthesis zinc-dependent hydrolase 1783390 pksB 939445 pksB Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis zinc-dependent hydrolase NP_389590.1 1782713 D 224308 CDS NP_389591.1 16078772 939504 1783763..1784629 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme; polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC 1784629 pksC 939504 pksC Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis malonyl CoA-acyl carrier protein transacylase PksC NP_389591.1 1783763 D 224308 CDS NP_389592.2 255767392 939463 1785133..1786107 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme; polyketide biosynthesis acyltransferase homolog PksD 1786107 pksD 939463 pksD Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis acyltransferase homolog PksD NP_389592.2 1785133 D 224308 CDS NP_389593.3 255767393 939997 1786104..1788407 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16707694; Product type e: enzyme; polyketide biosynthesis protein PksE 1788407 pksE 939997 pksE Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis protein PksE NP_389593.3 1786104 D 224308 CDS NP_570904.1 18677776 937952 1788469..1788717 1 NC_000964.3 Acyl carrier proteins are involved in the biosynthetic pathways of fatty acids, phospholipids, lipopolysaccharides, and oligosaccharides; this ACP may be involved in the biosynthesis of lipopeptide antibiotics; polyketide biosynthesis acyl-carrier-protein AcpK 1788717 acpK 937952 acpK Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis acyl-carrier-protein AcpK NP_570904.1 1788469 D 224308 CDS NP_389594.2 255767394 939500 1788695..1789942 1 NC_000964.3 involved in polyketide production; polyketide biosynthesis malonyl-ACP decarboxylase PksF 1789942 pksF 939500 pksF Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis malonyl-ACP decarboxylase PksF NP_389594.2 1788695 D 224308 CDS NP_389595.2 50812233 940121 1789943..1791205 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561; Product type e: enzyme; polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG 1791205 pksG 940121 pksG Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG NP_389595.2 1789943 D 224308 CDS NP_389596.1 16078777 940033 1791193..1791972 1 NC_000964.3 involved in polyketide synthesis; polyketide biosynthesis enoyl-CoA hydratase PksH 1791972 pksH 940033 pksH Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis enoyl-CoA hydratase PksH NP_389596.1 1791193 D 224308 CDS NP_389597.2 255767395 940096 1792012..1792761 1 NC_000964.3 involved in polyketide production; polyketide biosynthesis enoyl-CoA isomerase PksI 1792761 pksI 940096 pksI Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis enoyl-CoA isomerase PksI NP_389597.2 1792012 D 224308 CDS NP_389598.3 255767396 940043 1792806..1807937 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16460000, 16707694; Product type e: enzyme; polyketide synthase PksJ 1807937 pksJ 940043 pksJ Bacillus subtilis subsp. subtilis str. 168 polyketide synthase PksJ NP_389598.3 1792806 D 224308 CDS NP_389600.3 255767397 940032 1807921..1821537 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16757561, 17042494; Product type e: enzyme; polyketide synthase PksL 1821537 pksL 940032 pksL Bacillus subtilis subsp. subtilis str. 168 polyketide synthase PksL NP_389600.3 1807921 D 224308 CDS NP_389601.3 255767398 940026 1821553..1834341 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15480790; Product type e: enzyme; polyketide synthase PksM 1834341 pksM 940026 pksM Bacillus subtilis subsp. subtilis str. 168 polyketide synthase PksM NP_389601.3 1821553 D 224308 CDS NP_389602.3 255767399 940054 1834409..1850875 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16460000; Product type e: enzyme; polyketide synthase PksN 1850875 pksN 940054 pksN Bacillus subtilis subsp. subtilis str. 168 polyketide synthase PksN NP_389602.3 1834409 D 224308 CDS NP_389604.2 255767400 940036 1850890..1858521 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960106, 15480790; Product type e: enzyme; polyketide synthase PksR 1858521 pksR 940036 pksR Bacillus subtilis subsp. subtilis str. 168 polyketide synthase PksR NP_389604.2 1850890 D 224308 CDS NP_389605.2 255767401 940046 complement(1858566..1859783) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17482575; Product type e: enzyme; polyketide biosynthesis cytochrome P450 PksS 1859783 pksS 940046 pksS Bacillus subtilis subsp. subtilis str. 168 polyketide biosynthesis cytochrome P450 PksS NP_389605.2 1858566 R 224308 CDS NP_389606.3 255767402 940041 complement(1860014..1860370) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1860370 ymzB 940041 ymzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389606.3 1860014 R 224308 CDS NP_389607.2 255767403 940045 complement(1860449..1861273) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1861273 ymaE 940045 ymaE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389607.2 1860449 R 224308 CDS NP_389608.1 16078789 940056 complement(1861384..1862712) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589719, 16267290, 17884659; Product type e: enzyme; serine protease AprX 1862712 aprX 940056 aprX Bacillus subtilis subsp. subtilis str. 168 serine protease AprX NP_389608.1 1861384 R 224308 CDS NP_389609.1 16078790 940071 1863448..1864155 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type h : extrachromosomal origin; hypothetical protein 1864155 ymaC 940071 ymaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389609.1 1863448 D 224308 CDS NP_389610.1 16078791 940058 1864225..1864677 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 1864677 ymaD 940058 ymaD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389610.1 1864225 D 224308 CDS NP_389611.1 16078792 940051 complement(1864691..1865044) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 15849754, 16750162, 16850406; Product type t: transporter; multidrug resistance protein EbrB 1865044 ebrB 940051 ebrB Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein EbrB NP_389611.1 1864691 R 224308 CDS NP_389612.1 16078793 940059 complement(1865058..1865375) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735876, 11104814, 17516673; Product type t: transporter; multidrug resistance protein EbrA 1865375 ebrA 940059 ebrA Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein EbrA NP_389612.1 1865058 R 224308 CDS NP_389613.2 255767404 940062 complement(1865512..1865787) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1865787 ymaG 940062 ymaG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389613.2 1865512 R 224308 CDS NP_389614.2 255767405 940060 1865876..1866289 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1866289 ymaF 940060 ymaF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389614.2 1865876 D 224308 CDS NP_389615.2 255767406 940067 1866389..1867333 1 NC_000964.3 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA dimethylallyltransferase 1867333 miaA 940067 miaA Bacillus subtilis subsp. subtilis str. 168 tRNA dimethylallyltransferase NP_389615.2 1866389 D 224308 CDS NP_389616.1 16078797 940073 1867373..1867594 1 NC_000964.3 Stimulates the elongation of poly(A) tails; RNA-binding protein Hfq 1867594 hfq 940073 hfq Bacillus subtilis subsp. subtilis str. 168 RNA-binding protein Hfq NP_389616.1 1867373 D 224308 CDS NP_389617.1 16078798 940085 1867790..1868062 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1868062 ymzC 940085 ymzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389617.1 1867790 D 224308 CDS NP_389618.1 16078799 940080 1868144..1868374 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1868374 ymzA 940080 ymzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389618.1 1868144 D 224308 CDS NP_389619.1 16078800 940075 1868617..1869009 1 NC_000964.3 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein NrdI 1869009 nrdI 940075 nrdI Bacillus subtilis subsp. subtilis str. 168 ribonucleotide reductase stimulatory protein NrdI NP_389619.1 1868617 D 224308 CDS NP_389620.1 16078801 940091 1868969..1871071 1 NC_000964.3 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleoside-diphosphate reductase subunit alpha 1871071 nrdE 940091 nrdE Bacillus subtilis subsp. subtilis str. 168 ribonucleoside-diphosphate reductase subunit alpha NP_389620.1 1868969 D 224308 CDS NP_389621.1 16078802 940076 1871089..1872078 1 NC_000964.3 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleoside-diphosphate reductase subunit beta 1872078 nrdF 940076 nrdF Bacillus subtilis subsp. subtilis str. 168 ribonucleoside-diphosphate reductase subunit beta NP_389621.1 1871089 D 224308 CDS NP_389622.1 16078803 939453 1872128..1872748 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885274; Product type pe : enzyme; hypothetical protein 1872748 ymaB 939453 ymaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389622.1 1872128 D 224308 CDS NP_389623.2 255767407 940088 complement(1872812..1873579) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10945275, 10974124, 11375403, 16042392; Product type e: enzyme; sporulation-specific N-acetylmuramoyl-L-alanine amidase 1873579 cwlC 940088 cwlC Bacillus subtilis subsp. subtilis str. 168 sporulation-specific N-acetylmuramoyl-L-alanine amidase NP_389623.2 1872812 R 224308 CDS NP_389624.2 255767408 940089 1874203..1875171 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8464402; Product type cp: cell process; stage V sporulation protein K 1875171 spoVK 940089 spoVK Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein K NP_389624.2 1874203 D 224308 CDS NP_389625.2 255767409 938169 1875304..1876566 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; GTPase HflX 1876566 ynbA 938169 ynbA Bacillus subtilis subsp. subtilis str. 168 GTPase HflX NP_389625.2 1875304 D 224308 CDS NP_389626.2 255767410 940047 1876584..1877849 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1877849 ynbB 940047 ynbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389626.2 1876584 D 224308 CDS NP_389627.1 16078808 940070 1877959..1878366 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12374841, 16547045, 16885465, 9287005; Product type r: regulator; MerR family transcriptional regulator 1878366 glnR 940070 glnR Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_389627.1 1877959 D 224308 CDS NP_389628.1 16078809 940020 1878425..1879759 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11719184, 12142436, 13737, 16055443, 16885465; Product type e: enzyme; glutamine synthetase 1879759 glnA 940020 glnA Bacillus subtilis subsp. subtilis str. 168 glutamine synthetase NP_389628.1 1878425 D 224308 CDS NP_389629.1 16078810 939610 1880087..1880377 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 1880377 ynxB 939610 ynxB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389629.1 1880087 D 224308 CDS NP_389630.1 16078811 939642 1880623..1880967 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1880967 ynzF 939642 ynzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389630.1 1880623 D 224308 CDS NP_389631.1 16078812 938126 1881098..1881349 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1881349 ynzG 938126 ynzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389631.1 1881098 D 224308 CDS NP_389632.2 255767411 940017 1881536..1881970 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1881970 ynaB 940017 ynaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389632.2 1881536 D 224308 CDS NP_389633.1 16078814 936647 1882040..1882831 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1882831 ynaC 936647 ynaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389633.1 1882040 D 224308 CDS NP_389634.1 16078815 936242 1883166..1883678 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YnaD 1883678 ynaD 936242 ynaD Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YnaD NP_389634.1 1883166 D 224308 CDS NP_389635.1 16078816 936948 1884238..1884879 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1884879 ynaE 936948 ynaE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389635.1 1884238 D 224308 CDS NP_389636.1 16078817 938101 1884968..1885321 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1885321 ynaF 938101 ynaF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389636.1 1884968 D 224308 CDS NP_389637.1 16078818 940014 1885365..1885640 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1885640 ynaG 940014 ynaG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389637.1 1885365 D 224308 CDS YP_003097730.1 255767412 8303140 1885753..1885917 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1885917 ynzI 8303140 ynzI Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097730.1 1885753 D 224308 CDS NP_389638.3 255767413 940011 1886057..1886527 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1886527 ynaI 940011 ynaI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389638.3 1886057 D 224308 CDS NP_389639.2 255767414 939533 1887352..1888743 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16684115, 16850406, 17183216; Product type pt: transporter; symporter 1888743 xynP 939533 xynP Bacillus subtilis subsp. subtilis str. 168 symporter NP_389639.2 1887352 D 224308 CDS NP_389640.2 255767415 939472 1888774..1890375 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16684115, 2440680, 6413490, 7816035, 9286998, 9973552; Product type e : enzyme; beta-xylosidase 1890375 xynB 939472 xynB Bacillus subtilis subsp. subtilis str. 168 beta-xylosidase NP_389640.2 1888774 D 224308 CDS NP_389641.2 255767416 939531 complement(1890512..1891564) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1588910, 1719948, 2544559, 7559331; Product type r: regulator; transcriptional regulator 1891564 xylR 939531 xylR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_389641.2 1890512 R 224308 CDS NP_389642.2 255767417 939558 1891908..1893245 1 NC_000964.3 catalyzes the interconversion of D-xylose to D-xylulose; xylose isomerase 1893245 xylA 939558 xylA Bacillus subtilis subsp. subtilis str. 168 xylose isomerase NP_389642.2 1891908 D 224308 CDS NP_389643.1 16078824 939560 1893396..1894895 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1660563, 8866023; Product type e: enzyme; xylulose kinase 1894895 xylB 939560 xylB Bacillus subtilis subsp. subtilis str. 168 xylulose kinase NP_389643.1 1893396 D 224308 CDS NP_389644.1 16078825 939569 complement(1895378..1896013) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type e: enzyme; endonuclease 1896013 yncB 939569 yncB Bacillus subtilis subsp. subtilis str. 168 endonuclease NP_389644.1 1895378 R 224308 CDS NP_389645.2 255767418 939540 1896424..1897839 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transport protein YncC 1897839 yncC 939540 yncC Bacillus subtilis subsp. subtilis str. 168 metabolite transport protein YncC NP_389645.2 1896424 D 224308 CDS NP_389646.1 16078827 939550 complement(1897941..1899125) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10348844, 18399999; Product type e: enzyme; alanine racemase 2 1899125 alrB 939550 alrB Bacillus subtilis subsp. subtilis str. 168 alanine racemase 2 NP_389646.1 1897941 R 224308 CDS NP_389648.2 255767419 939573 1899589..1900050 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1900050 yncE 939573 yncE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389648.2 1899589 D 224308 CDS NP_389649.1 16078829 939541 1900080..1900514 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15939294, 16908222, 17169987; Product type h: extrachromosomal origin; deoxyuridine 5'-triphosphate nucleotidohydrolase YncF 1900514 yncF 939541 yncF Bacillus subtilis subsp. subtilis str. 168 deoxyuridine 5'-triphosphate nucleotidohydrolase YncF NP_389649.1 1900080 D 224308 CDS NP_389650.1 16078830 939580 complement(1901117..1901377) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816, 18065538; Product type f: factor; hypothetical protein 1901377 cotU 939580 cotU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389650.1 1901117 R 224308 CDS NP_389651.1 16078831 939555 1902219..1903058 1 NC_000964.3 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 1903058 thyA 939555 thyA Bacillus subtilis subsp. subtilis str. 168 thymidylate synthase NP_389651.1 1902219 D 224308 CDS NP_389652.1 16078832 939576 complement(1903511..1904263) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1904263 yncM 939576 yncM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389652.1 1903511 R 224308 CDS YP_003097731.1 255767420 8303021 complement(1904393..1904749) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 1904749 ynzK 8303021 ynzK Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097731.1 1904393 R 224308 CDS NP_389653.2 255767421 939543 complement(1904995..1905195) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10788508, 11741866, 14762008, 18065538, 2821284; Product type s: structure; spore coat protein C 1905195 cotC 939543 cotC Bacillus subtilis subsp. subtilis str. 168 spore coat protein C NP_389653.2 1904995 R 224308 CDS NP_389654.1 16078834 939527 complement(1905370..1905558) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11007775; Product type t: transporter; Sec-independent protein translocase protein TatAc 1905558 tatAC 939527 tatAC Bacillus subtilis subsp. subtilis str. 168 Sec-independent protein translocase protein TatAc NP_389654.1 1905370 R 224308 CDS NP_389655.1 16078835 939521 1905809..1906207 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1906207 yndA 939521 yndA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389655.1 1905809 D 224308 CDS NP_389656.1 16078836 939524 complement(1906272..1906706) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1906706 yndB 939524 yndB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389656.1 1906272 R 224308 CDS NP_389657.2 255767422 939516 1907013..1907201 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 1907201 ynzB 939516 ynzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389657.2 1907013 D 224308 CDS NP_389658.1 16078838 939529 1907494..1909056 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type pf : factor; membrane protein 1909056 yndD 939529 yndD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389658.1 1907494 D 224308 CDS NP_389659.1 16078839 936538 1909086..1910177 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253, 15849754, 16850406; Product type pm: membrane component; spore germination protein YndE 1910177 yndE 936538 yndE Bacillus subtilis subsp. subtilis str. 168 spore germination protein YndE NP_389659.1 1909086 D 224308 CDS NP_389660.1 16078840 939547 1910167..1911381 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10762253; Product type lp : lipoprotein; spore germination protein YndF 1911381 yndF 939547 yndF Bacillus subtilis subsp. subtilis str. 168 spore germination protein YndF NP_389660.1 1910167 D 224308 CDS NP_389661.1 16078841 939565 1911528..1912334 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 1912334 yndG 939565 yndG Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389661.1 1911528 D 224308 CDS NP_389662.1 16078842 939537 1912339..1912956 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1912956 yndH 939537 yndH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389662.1 1912339 D 224308 CDS NP_389663.1 16078843 939575 1912953..1914593 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1914593 yndJ 939575 yndJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389663.1 1912953 D 224308 CDS NP_389664.1 16078844 936932 1914630..1914995 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 1914995 yndK 936932 yndK Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389664.1 1914630 D 224308 CDS NP_389665.1 16078845 939553 1915221..1915979 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 1915979 yndL 939553 yndL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389665.1 1915221 D 224308 CDS NP_389666.1 16078846 938236 complement(1916006..1916545) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1916545 yndM 938236 yndM Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389666.1 1916006 R 224308 CDS NP_389667.1 16078847 938817 1916663..1917097 1 NC_000964.3 catalyzes resistance to fosfomycin by the addition of a thiol cofactor; metallothiol transferase FosB 1917097 yndN 938817 yndN Bacillus subtilis subsp. subtilis str. 168 metallothiol transferase FosB NP_389667.1 1916663 D 224308 CDS NP_389668.1 16078848 939564 complement(1917639..1918256) 1 NC_000964.3 Represses a number of genes involved in the response to DNA damage; lexa repressor 1918256 lexA 939564 lexA Bacillus subtilis subsp. subtilis str. 168 lexa repressor NP_389668.1 1917639 R 224308 CDS NP_389669.1 16078849 936112 1918406..1918723 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12581363, 16267290, 16549676; Product type cp: cell process; cell division suppressor protein YneA 1918723 yneA 936112 yneA Bacillus subtilis subsp. subtilis str. 168 cell division suppressor protein YneA NP_389669.1 1918406 D 224308 CDS NP_389670.1 16078850 939557 1918742..1919395 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12581363, 16267290, 17020588; Product type cp: cell process; resolvase homolog YneB 1919395 yneB 939557 yneB Bacillus subtilis subsp. subtilis str. 168 resolvase homolog YneB NP_389670.1 1918742 D 224308 CDS NP_389671.1 16078851 939578 1919459..1919692 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12581363, 16267290, 18431750; hypothetical protein 1919692 ynzC 939578 ynzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389671.1 1919459 D 224308 CDS NP_389672.1 16078852 937377 1919861..1921864 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 12882400; Product type e: enzyme; transketolase 1921864 tkt 937377 tkt Bacillus subtilis subsp. subtilis str. 168 transketolase NP_389672.1 1919861 D 224308 CDS NP_389673.1 16078853 936340 1922017..1922463 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; sporulation inhibitor of replication protein SirA 1922463 yneE 936340 yneE Bacillus subtilis subsp. subtilis str. 168 sporulation inhibitor of replication protein SirA NP_389673.1 1922017 D 224308 CDS NP_389674.1 16078854 939469 1922549..1922767 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1922767 yneF 939469 yneF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389674.1 1922549 D 224308 CDS NP_389675.1 16078855 938818 complement(1922841..1923014) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11679073; Product type e: enzyme; aspartyl-phosphate phosphatase YnzD 1923014 ynzD 938818 ynzD Bacillus subtilis subsp. subtilis str. 168 aspartyl-phosphate phosphatase YnzD NP_389675.1 1922841 R 224308 CDS NP_389676.1 16078856 937140 1923234..1923941 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16771673, 16850406; Product type e: enzyme; cytochrome c-type biogenesis protein CcdA 1923941 ccdA 937140 ccdA Bacillus subtilis subsp. subtilis str. 168 cytochrome c-type biogenesis protein CcdA NP_389676.1 1923234 D 224308 CDS NP_389677.1 16078857 939468 1924030..1924392 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554; Product type pr : regulator; plasmid maintenance protein CcdB 1924392 yneI 939468 yneI Bacillus subtilis subsp. subtilis str. 168 plasmid maintenance protein CcdB NP_389677.1 1924030 D 224308 CDS NP_389678.1 16078858 938604 1924471..1924962 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10781554, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1924962 yneJ 938604 yneJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389678.1 1924471 D 224308 CDS NP_389679.1 16078859 938820 complement(1924993..1925421) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1925421 yneK 938820 yneK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389679.1 1924993 R 224308 CDS NP_389680.1 16078860 938815 complement(1925655..1926047) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11150673, 9068633; Product type m: membrane component; spore coat protein M 1926047 cotM 938815 cotM Bacillus subtilis subsp. subtilis str. 168 spore coat protein M NP_389680.1 1925655 R 224308 CDS NP_389681.1 16078861 938192 complement(1926128..1926274) 1 NC_000964.3 SASP P; found in forespore compartment; small acid-soluble spore protein P 1926274 sspP 938192 sspP Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein P NP_389681.1 1926128 R 224308 CDS NP_389682.1 16078862 938222 complement(1926306..1926452) 1 NC_000964.3 SASP O; found in forespore compartment; small acid-soluble spore protein O 1926452 sspO 938222 sspO Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein O NP_389682.1 1926306 R 224308 CDS NP_389683.1 16078863 938140 1926680..1929409 1 NC_000964.3 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 1929409 citB 938140 citB Bacillus subtilis subsp. subtilis str. 168 aconitate hydratase NP_389683.1 1926680 D 224308 CDS NP_389684.1 16078864 938193 1929481..1929993 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15342593; Product type pe : enzyme; thioredoxin 1929993 yneN 938193 yneN Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_389684.1 1929481 D 224308 CDS YP_003097732.1 255767423 8302958 1930074..1930199 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1930199 ynzL 8302958 ynzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097732.1 1930074 D 224308 CDS YP_054579.2 255767424 2914184 1930264..1930410 1 NC_000964.3 SASP N; found in forespore compartment; small acid-soluble spore protein N 1930410 sspN 2914184 sspN Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein N YP_054579.2 1930264 D 224308 CDS NP_389685.1 16078865 938091 1930447..1930698 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type f: factor; small acid-soluble spore protein Tlp 1930698 tlp 938091 tlp Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein Tlp NP_389685.1 1930447 D 224308 CDS YP_054580.1 50812241 2914242 1930834..1931199 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl-CoA thioesterase 1931199 yneP 2914242 yneP Bacillus subtilis subsp. subtilis str. 168 acyl-CoA thioesterase YP_054580.1 1930834 D 224308 CDS NP_389687.1 16078866 937998 1931215..1931514 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1931514 yneQ 937998 yneQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389687.1 1931215 D 224308 CDS NP_389688.1 16078867 938132 complement(1931545..1931832) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1931832 yneR 938132 yneR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389688.1 1931545 R 224308 CDS NP_389689.1 16078868 938037 complement(1931920..1932501) 1 NC_000964.3 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase 1932501 yneS 938037 yneS Bacillus subtilis subsp. subtilis str. 168 glycerol-3-phosphate acyltransferase NP_389689.1 1931920 R 224308 CDS NP_389690.1 16078869 938220 1932671..1933078 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 1933078 yneT 938220 yneT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389690.1 1932671 D 224308 CDS NP_389691.2 50812242 936151 1933477..1935444 1 NC_000964.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase 4 subunit B 1935444 parE 936151 parE Bacillus subtilis subsp. subtilis str. 168 DNA topoisomerase 4 subunit B NP_389691.2 1933477 D 224308 CDS NP_389692.2 255767425 937107 1935448..1937868 1 NC_000964.3 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase 4 subunit A 1937868 parC 937107 parC Bacillus subtilis subsp. subtilis str. 168 DNA topoisomerase 4 subunit A NP_389692.2 1935448 D 224308 CDS NP_389693.1 16078872 937092 complement(1938066..1938476) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1938476 ynfC 937092 ynfC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389693.1 1938066 R 224308 CDS NP_389694.1 16078873 938191 1938925..1940322 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12823818, 15849754, 16850406, 8969507; Product type t: transporter; amino acid carrier protein AlsT 1940322 alsT 938191 alsT Bacillus subtilis subsp. subtilis str. 168 amino acid carrier protein AlsT NP_389694.1 1938925 D 224308 CDS NP_389695.2 50812243 938607 1940625..1942124 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15139916, 3024130, 7710279; Product type e: enzyme; endoglucanase 1942124 eglS 938607 eglS Bacillus subtilis subsp. subtilis str. 168 endoglucanase NP_389695.2 1940625 D 224308 CDS NP_389696.1 16078875 936469 1942192..1942455 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1942455 ynfE 936469 ynfE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389696.1 1942192 D 224308 CDS NP_389697.1 16078876 937052 complement(1942714..1943982) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17028274; Product type e: enzyme; glucuronoxylanase XynC 1943982 xynC 937052 xynC Bacillus subtilis subsp. subtilis str. 168 glucuronoxylanase XynC NP_389697.1 1942714 R 224308 CDS NP_389698.1 16078877 936433 complement(1944113..1945654) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1938968; Product type e : enzyme; arabinoxylan arabinofuranohydrolase 1945654 xynD 936433 xynD Bacillus subtilis subsp. subtilis str. 168 arabinoxylan arabinofuranohydrolase NP_389698.1 1944113 R 224308 CDS NP_389699.1 16078878 936300 1946249..1946695 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1946695 yngA 936300 yngA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389699.1 1946249 D 224308 CDS NP_389700.1 16078879 936791 1946702..1947595 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8320212; Product type pe : enzyme; UTP--glucose-1-phosphate uridylyltransferase YngB 1947595 yngB 936791 yngB Bacillus subtilis subsp. subtilis str. 168 UTP--glucose-1-phosphate uridylyltransferase YngB NP_389700.1 1946702 D 224308 CDS NP_389701.1 16078880 939567 1947668..1948264 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 1948264 yngC 939567 yngC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389701.1 1947668 D 224308 CDS NP_389702.1 16078881 936020 complement(1948313..1949512) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oligoribonuclease NrnB 1949512 yngD 936020 yngD Bacillus subtilis subsp. subtilis str. 168 oligoribonuclease NrnB NP_389702.1 1948313 R 224308 CDS NP_389703.2 255767426 939528 complement(1949682..1951217) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carboxylase YngE 1951217 yngE 939528 yngE Bacillus subtilis subsp. subtilis str. 168 carboxylase YngE NP_389703.2 1949682 R 224308 CDS NP_389704.1 16078883 939467 complement(1951228..1952010) 1 NC_000964.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase/isomerase YngF 1952010 yngF 939467 yngF Bacillus subtilis subsp. subtilis str. 168 enoyl-CoA hydratase/isomerase YngF NP_389704.1 1951228 R 224308 CDS NP_389705.1 16078884 939515 complement(1952031..1952930) 1 NC_000964.3 catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA; hydroxymethylglutaryl-CoA lyase YngG 1952930 yngG 939515 yngG Bacillus subtilis subsp. subtilis str. 168 hydroxymethylglutaryl-CoA lyase YngG NP_389705.1 1952031 R 224308 CDS YP_003097733.1 255767427 8303012 complement(1952945..1953166) 1 NC_000964.3 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin/lipoyl attachment protein 1953166 yngHB 8303012 yngHB Bacillus subtilis subsp. subtilis str. 168 biotin/lipoyl attachment protein YP_003097733.1 1952945 R 224308 CDS NP_389706.1 16078885 939474 complement(1953181..1954515) 1 NC_000964.3 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 2 1954515 yngH 939474 yngH Bacillus subtilis subsp. subtilis str. 168 biotin carboxylase 2 NP_389706.1 1953181 R 224308 CDS NP_389707.1 16078886 939571 complement(1954525..1956174) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12535077, 15213221; Product type e: enzyme; acyl-CoA synthetase YngI 1956174 yngI 939571 yngI Bacillus subtilis subsp. subtilis str. 168 acyl-CoA synthetase YngI NP_389707.1 1954525 R 224308 CDS NP_389708.1 16078887 939996 complement(1956218..1957360) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8655474; Product type e: enzyme; acyl-CoA dehydrogenase YngJ 1957360 yngJ 939996 yngJ Bacillus subtilis subsp. subtilis str. 168 acyl-CoA dehydrogenase YngJ NP_389708.1 1956218 R 224308 CDS NP_389709.1 16078888 939980 complement(1957451..1957756) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 1957756 ynzE 939980 ynzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389709.1 1957451 R 224308 CDS NP_389710.1 16078889 939977 complement(1958027..1959559) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type ps : structure; hypothetical protein 1959559 yngK 939977 yngK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389710.1 1958027 R 224308 CDS NP_389711.1 16078890 939955 complement(1959695..1960087) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 1960087 yngL 939955 yngL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389711.1 1959695 R 224308 CDS NP_389712.1 16078891 939956 complement(1960198..1964037) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486459, 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit E 1964037 ppsE 939956 ppsE Bacillus subtilis subsp. subtilis str. 168 plipastatin synthase subunit E NP_389712.1 1960198 R 224308 CDS NP_389713.2 255767428 940013 complement(1964045..1974856) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit D 1974856 ppsD 940013 ppsD Bacillus subtilis subsp. subtilis str. 168 plipastatin synthase subunit D NP_389713.2 1964045 R 224308 CDS NP_389714.1 16078893 940102 complement(1974881..1982548) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit C 1982548 ppsC 940102 ppsC Bacillus subtilis subsp. subtilis str. 168 plipastatin synthase subunit C NP_389714.1 1974881 R 224308 CDS NP_389715.1 16078894 939993 complement(1982565..1990247) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit B 1990247 ppsB 939993 ppsB Bacillus subtilis subsp. subtilis str. 168 plipastatin synthase subunit B NP_389715.1 1982565 R 224308 CDS NP_389716.2 255767429 939983 complement(1990272..1997957) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9889147, 10471562; Product type e: enzyme; plipastatin synthase subunit A 1997957 ppsA 939983 ppsA Bacillus subtilis subsp. subtilis str. 168 plipastatin synthase subunit A NP_389716.2 1990272 R 224308 CDS NP_389717.1 16078896 939990 complement(1998340..1999815) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160090, 14731276, 9733705, 9864321; Product type e: enzyme; D-alanyl-D-alanine carboxypeptidase DacC 1999815 dacC 939990 dacC Bacillus subtilis subsp. subtilis str. 168 D-alanyl-D-alanine carboxypeptidase DacC NP_389717.1 1998340 R 224308 CDS NP_389718.1 16078897 938046 complement(1999849..2000826) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9733705; Product type pe : enzyme; aldose 1-epimerase 2000826 yoxA 938046 yoxA Bacillus subtilis subsp. subtilis str. 168 aldose 1-epimerase NP_389718.1 1999849 R 224308 CDS NP_389719.2 255767430 939596 complement(2000960..2002351) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; multidrug resistance protein 2002351 yoeA 939596 yoeA Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_389719.2 2000960 R 224308 CDS NP_389720.2 255767431 939964 2002637..2003182 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483219, 17581128, 18761694; Product type f: factor; hypothetical protein 2003182 iseA 939964 iseA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389720.2 2002637 D 224308 CDS NP_389721.2 255767432 939595 complement(2003401..2003946) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; integrase/recombinase YoeC 2003946 yoeC 939595 yoeC Bacillus subtilis subsp. subtilis str. 168 integrase/recombinase YoeC NP_389721.2 2003401 R 224308 CDS NP_389722.1 16078901 939991 complement(2004262..2004492) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16880568; Product type pe : enzyme; hypothetical protein 2004492 yoeD 939991 yoeD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389722.1 2004262 R 224308 CDS NP_389723.1 16078902 940001 2004677..2006440 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8763966; Product type e : enzyme; gamma-glutamyltranspeptidase 2006440 ggt 940001 ggt Bacillus subtilis subsp. subtilis str. 168 gamma-glutamyltranspeptidase NP_389723.1 2004677 D 224308 CDS NP_389724.1 16078903 940018 complement(2006541..2007398) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17526699; Product type r: regulator; LysR family transcriptional regulator 2007398 ftsR 940018 ftsR Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_389724.1 2006541 R 224308 CDS NP_389725.1 16078904 940019 2007526..2008515 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106; Product type pe : enzyme; zinc-type alcohol dehydrogenase 2008515 yogA 940019 yogA Bacillus subtilis subsp. subtilis str. 168 zinc-type alcohol dehydrogenase NP_389725.1 2007526 D 224308 CDS NP_389726.2 255767433 940053 complement(2008572..2010053) 1 NC_000964.3 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; glutamate synthase [NADPH] small chain 2010053 gltD 940053 gltD Bacillus subtilis subsp. subtilis str. 168 glutamate synthase [NADPH] small chain NP_389726.2 2008572 R 224308 CDS NP_389727.2 255767434 940024 complement(2010070..2014632) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14570271, 39113, 6769440, 6774712, 7559359; Product type e: enzyme; glutamate synthase [NADPH] large chain 2014632 gltA 940024 gltA Bacillus subtilis subsp. subtilis str. 168 glutamate synthase [NADPH] large chain NP_389727.2 2010070 R 224308 CDS NP_389728.2 255767435 940104 2014779..2015681 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15150225, 17134717, 2548995; Product type r: regulator; LysR family transcriptional regulator 2015681 gltC 940104 gltC Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_389728.2 2014779 D 224308 CDS NP_389729.1 16078908 940098 complement(2015733..2016848) 1 NC_000964.3 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; glutamate 5-kinase 2016848 proJ 940098 proJ Bacillus subtilis subsp. subtilis str. 168 glutamate 5-kinase NP_389729.1 2015733 R 224308 CDS NP_389730.2 50812244 940035 complement(2016845..2017738) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme; pyrroline-5-carboxylate reductase 1 2017738 proH 940035 proH Bacillus subtilis subsp. subtilis str. 168 pyrroline-5-carboxylate reductase 1 NP_389730.2 2016845 R 224308 CDS NP_389731.1 16078910 940068 complement(2017886..2018254) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11313334, 15657033, 16822523, 17376071, 17521668; Product type f: factor; replication termination protein 2018254 rtp 940068 rtp Bacillus subtilis subsp. subtilis str. 168 replication termination protein NP_389731.1 2017886 R 224308 CDS NP_389732.1 16078911 940090 complement(2018554..2019270) 1 NC_000964.3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 2019270 fabG 940090 fabG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389732.1 2018554 R 224308 CDS NP_389733.1 16078912 940083 2019421..2019726 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2019726 yoxC 940083 yoxC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389733.1 2019421 D 224308 CDS NP_389734.1 16078913 940087 2019797..2020567 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2020567 yoxB 940087 yoxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389734.1 2019797 D 224308 CDS NP_389735.2 255767436 940097 2020611..2021144 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; N-acetyltransferase YoaA 2021144 yoaA 940097 yoaA Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YoaA NP_389735.2 2020611 D 224308 CDS NP_389736.1 16078915 940099 complement(2021223..2022467) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 15849754, 16513748, 16850406; Product type t: transporter; transporter 2022467 yoaB 940099 yoaB Bacillus subtilis subsp. subtilis str. 168 transporter NP_389736.1 2021223 R 224308 CDS NP_389737.1 16078916 940100 complement(2022561..2024024) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12193636, 1660563, 10094622; Product type e: enzyme; sugar kinase YoaC 2024024 yoaC 940100 yoaC Bacillus subtilis subsp. subtilis str. 168 sugar kinase YoaC NP_389737.1 2022561 R 224308 CDS NP_389738.1 16078917 940109 complement(2024042..2025076) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 12193636, 10094622; Product type pe: enzyme; 2-hydroxyacid dehydrogenase YoaD 2025076 yoaD 940109 yoaD Bacillus subtilis subsp. subtilis str. 168 2-hydroxyacid dehydrogenase YoaD NP_389738.1 2024042 R 224308 CDS NP_389739.2 255767437 940113 2025400..2027442 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 17114254, 2170332; Product type e : enzyme; oxidoreductase 2027442 yoaE 940113 yoaE Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_389739.2 2025400 D 224308 CDS NP_389740.1 16078919 940103 2027509..2027802 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2027802 yoaF 940103 yoaF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389740.1 2027509 D 224308 CDS NP_389741.1 16078920 940105 complement(2028175..2028579) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2028579 yoaG 940105 yoaG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389741.1 2028175 R 224308 CDS YP_054581.1 50812245 2914173 2029020..2029313 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2029313 yozQ 2914173 yozQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054581.1 2029020 D 224308 CDS NP_389742.2 255767438 940110 complement(2029429..2031114) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type pf : factor; methyl-accepting chemotaxis protein YoaH 2031114 yoaH 940110 yoaH Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein YoaH NP_389742.2 2029429 R 224308 CDS NP_389743.2 255767439 940107 2031439..2032890 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 4-hydroxyphenylacetate 3-monooxygenase 2032890 yoaI 940107 yoaI Bacillus subtilis subsp. subtilis str. 168 4-hydroxyphenylacetate 3-monooxygenase NP_389743.2 2031439 D 224308 CDS NP_389744.1 16078923 940108 complement(2032927..2033625) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 18971341; Product type e: enzyme; expansin-YoaJ 2033625 exlX 940108 exlX Bacillus subtilis subsp. subtilis str. 168 expansin-YoaJ NP_389744.1 2032927 R 224308 CDS NP_389745.1 16078924 940007 complement(2033895..2034572) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2034572 yoaK 940007 yoaK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389745.1 2033895 R 224308 CDS NP_389746.1 16078925 940111 2034745..2035782 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1731776, 2018526, 2185758, 7764549; Product type e: enzyme; pectin lyase 2035782 pelB 940111 pelB Bacillus subtilis subsp. subtilis str. 168 pectin lyase NP_389746.1 2034745 D 224308 CDS NP_389747.1 16078926 940112 2036039..2036722 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2036722 yoaM 940112 yoaM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389747.1 2036039 D 224308 CDS YP_003097734.1 255767440 8302957 complement(2037063..2037368) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 2037368 yozS 8302957 yozS Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097734.1 2037063 R 224308 CDS NP_389748.1 16078927 940006 complement(2037601..2038779) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11546787, 14697267, 15628860; Product type e: enzyme; oxalate decarboxylase OxdD 2038779 yoaN 940006 yoaN Bacillus subtilis subsp. subtilis str. 168 oxalate decarboxylase OxdD NP_389748.1 2037601 R 224308 CDS NP_389749.1 16078928 940005 complement(2038902..2039390) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2039390 yoaO 940005 yoaO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389749.1 2038902 R 224308 CDS NP_389750.1 16078929 939512 complement(2039610..2040365) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; N-acetyltransferase YoaP 2040365 yoaP 939512 yoaP Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YoaP NP_389750.1 2039610 R 224308 CDS NP_389751.1 16078930 940010 2040673..2041029 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2041029 yoaQ 940010 yoaQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389751.1 2040673 D 224308 CDS YP_003097735.1 255767441 8303003 complement(2040988..2041227) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2041227 yozT 8303003 yozT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097735.1 2040988 R 224308 CDS NP_389752.2 255767442 939598 complement(2041330..2041827) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 2041827 yozF 939598 yozF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389752.2 2041330 R 224308 CDS NP_389753.1 16078932 939962 complement(2041928..2042839) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8631706; Product type pf : factor; hypothetical protein 2042839 yoaR 939962 yoaR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389753.1 2041928 R 224308 CDS NP_389754.1 16078933 939982 2043186..2043668 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 16850406; membrane protein 2043668 yoaS 939982 yoaS Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389754.1 2043186 D 224308 CDS NP_389755.1 16078934 940003 2043678..2043932 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2043932 yozG 940003 yozG Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389755.1 2043678 D 224308 CDS NP_389756.1 16078935 940132 2044038..2044832 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2044832 yoaT 940132 yoaT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389756.1 2044038 D 224308 CDS NP_389757.1 16078936 940127 complement(2044956..2045828) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator 2045828 yoaU 940127 yoaU Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_389757.1 2044956 R 224308 CDS NP_389758.1 16078937 940126 2045929..2046807 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter; transporter 2046807 cyeA 940126 cyeA Bacillus subtilis subsp. subtilis str. 168 transporter NP_389758.1 2045929 D 224308 CDS NP_389759.1 16078938 940131 complement(2046980..2047411) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989; Product type ph: phenotype; hypothetical protein 2047411 yoaW 940131 yoaW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389759.1 2046980 R 224308 CDS NP_389760.1 16078939 940031 complement(2047675..2048307) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16181642; Product type pf : factor; protease YoaZ 2048307 yoaZ 940031 yoaZ Bacillus subtilis subsp. subtilis str. 168 protease YoaZ NP_389760.1 2047675 R 224308 CDS NP_389761.1 16078940 940129 2048533..2049453 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16944130, 7789815; Product type e: enzyme; beta-lactamase 2049453 penP 940129 penP Bacillus subtilis subsp. subtilis str. 168 beta-lactamase NP_389761.1 2048533 D 224308 CDS NP_389762.1 16078941 940122 complement(2049950..2050312) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2050312 yobA 940122 yobA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389762.1 2049950 R 224308 CDS NP_389763.1 16078942 940049 2050689..2050952 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein 2050952 yobB 940049 yobB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389763.1 2050689 D 224308 CDS NP_389764.1 16078943 939985 complement(2051329..2053929) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphoenolpyruvate synthase 2053929 pps 939985 pps Bacillus subtilis subsp. subtilis str. 168 phosphoenolpyruvate synthase NP_389764.1 2051329 R 224308 CDS NP_389765.1 16078944 939861 complement(2054599..2055240) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16517552, 8628241; Product type e: enzyme; endo-1,4-beta-xylanase A 2055240 xynA 939861 xynA Bacillus subtilis subsp. subtilis str. 168 endo-1,4-beta-xylanase A NP_389765.1 2054599 R 224308 CDS YP_003097736.1 255767443 8303004 complement(2055868..2056107) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 2056107 yozV 8303004 yozV Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097736.1 2055868 R 224308 CDS NP_389766.1 16078945 939975 2056278..2056616 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; XRE family transcriptional regulator 2056616 yobD 939975 yobD Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389766.1 2056278 D 224308 CDS NP_389767.2 255767444 939603 complement(2056650..2057006) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2057006 yozH 939603 yozH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389767.2 2056650 R 224308 CDS NP_389768.1 16078947 939961 2057214..2057579 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2057579 yozI 939961 yozI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389768.1 2057214 D 224308 CDS NP_389769.1 16078948 939611 2057801..2058460 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2058460 yobE 939611 yobE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389769.1 2057801 D 224308 CDS NP_389770.1 16078949 939609 complement(2058715..2059638) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2059638 yobF 939609 yobF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389770.1 2058715 R 224308 CDS YP_003097737.1 255767445 8303072 complement(2059691..2059864) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2059864 yozW 8303072 yozW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097737.1 2059691 R 224308 CDS YP_003097738.1 255767446 8303068 2060009..2060233 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; protein YozX 2060233 yozX 8303068 yozX Bacillus subtilis subsp. subtilis str. 168 protein YozX YP_003097738.1 2060009 D 224308 CDS NP_389771.1 16078950 939606 complement(2060237..2060692) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2060692 yozJ 939606 yozJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389771.1 2060237 R 224308 CDS YP_003097739.1 255767447 8303063 2060817..2061077 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2061077 yozY 8303063 yozY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097739.1 2060817 D 224308 CDS NP_389772.1 16078951 939604 2062150..2063265 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16816200; Product type e: enzyme; response regulator aspartate phosphatase K 2063265 rapK 939604 rapK Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase K NP_389772.1 2062150 D 224308 CDS NP_389773.1 16078952 939608 2063262..2063384 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11587781, 16816200; Product type r: regulator; phosphatase RapK inhibitor 2063384 phrK 939608 phrK Bacillus subtilis subsp. subtilis str. 168 phosphatase RapK inhibitor NP_389773.1 2063262 D 224308 CDS NP_389774.2 255767448 939613 complement(2063510..2064163) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA repair protein 2064163 yobH 939613 yobH Bacillus subtilis subsp. subtilis str. 168 DNA repair protein NP_389774.2 2063510 R 224308 CDS NP_389775.1 16078954 939614 complement(2064200..2064547) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12137951; Product type h : extrachromosomal origin; DNA repair protein UvrX 2064547 yozK 939614 yozK Bacillus subtilis subsp. subtilis str. 168 DNA repair protein UvrX NP_389775.1 2064200 R 224308 CDS NP_389776.1 16078955 939619 complement(2064540..2064833) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951; hypothetical protein 2064833 yozL 939619 yozL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389776.1 2064540 R 224308 CDS NP_389777.1 16078956 939622 2065042..2065377 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; prophage-derived-like protein YozM 2065377 yozM 939622 yozM Bacillus subtilis subsp. subtilis str. 168 prophage-derived-like protein YozM NP_389777.1 2065042 D 224308 CDS NP_389778.1 16078957 939615 complement(2065424..2069029) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15128444; Product type pe : enzyme; membrane protein 2069029 yobI 939615 yobI Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389778.1 2065424 R 224308 CDS NP_389779.1 16078958 939633 complement(2070244..2071086) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2071086 yobJ 939633 yobJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389779.1 2070244 R 224308 CDS NP_389780.1 16078959 939629 complement(2071286..2071744) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2071744 yobK 939629 yobK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389780.1 2071286 R 224308 CDS NP_389781.1 16078960 939624 complement(2071754..2073556) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2073556 yobL 939624 yobL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389781.1 2071754 R 224308 CDS NP_389782.2 255767449 939634 complement(2073658..2074221) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2074221 yobM 939634 yobM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389782.2 2073658 R 224308 CDS NP_389783.1 16078962 939632 2074439..2075779 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amine oxidase 2075779 yobN 939632 yobN Bacillus subtilis subsp. subtilis str. 168 amine oxidase NP_389783.1 2074439 D 224308 CDS NP_389784.1 16078963 939627 2076206..2078626 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; phage-related protein YobO 2078626 yobO 939627 yobO Bacillus subtilis subsp. subtilis str. 168 phage-related protein YobO NP_389784.1 2076206 D 224308 CDS NP_389785.1 16078964 939631 complement(2079214..2079546) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658654, 10816431, 13129613, 15856219, 17372352; Product type f: factor; protein CsaA 2079546 csaA 939631 csaA Bacillus subtilis subsp. subtilis str. 168 protein CsaA NP_389785.1 2079214 R 224308 CDS NP_389786.1 16078965 939637 complement(2079611..2080336) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pr : regulator; AraC family transcriptional regulator 2080336 yobQ 939637 yobQ Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_389786.1 2079611 R 224308 CDS NP_389787.1 16078966 939650 complement(2080351..2081094) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; acetyltransferase 2081094 yobR 939650 yobR Bacillus subtilis subsp. subtilis str. 168 acetyltransferase NP_389787.1 2080351 R 224308 CDS NP_389788.1 16078967 939639 complement(2081172..2081747) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; TetR family transcriptional regulator 2081747 yobS 939639 yobS Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_389788.1 2081172 R 224308 CDS NP_389789.1 16078968 939645 complement(2081753..2082454) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2082454 yobT 939645 yobT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389789.1 2081753 R 224308 CDS NP_389790.1 16078969 939647 complement(2082531..2083013) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; transcriptional regulator 2083013 yobU 939647 yobU Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_389790.1 2082531 R 224308 CDS NP_389791.1 16078970 939644 complement(2083067..2084008) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; DeoR family transcriptional regulator 2084008 yobV 939644 yobV Bacillus subtilis subsp. subtilis str. 168 DeoR family transcriptional regulator NP_389791.1 2083067 R 224308 CDS NP_389792.1 16078971 939656 2084214..2084759 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 8990290; Product type f: factor; mother cell-specific membrane sporulation protein 2084759 yobW 939656 yobW Bacillus subtilis subsp. subtilis str. 168 mother cell-specific membrane sporulation protein NP_389792.1 2084214 D 224308 CDS NP_389793.1 16078972 939658 complement(2084786..2085109) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16430705; Product type r: regulator; ArsR family transcriptional regulator 2085109 czrA 939658 czrA Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_389793.1 2084786 R 224308 CDS NP_389794.1 16078973 939661 2085303..2085980 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; membrane protein 2085980 yocA 939661 yocA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389794.1 2085303 D 224308 CDS NP_389795.1 16078974 939655 complement(2086070..2086606) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2086606 yozB 939655 yozB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389795.1 2086070 R 224308 CDS NP_389796.1 16078975 939442 complement(2086743..2087525) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2087525 yocB 939442 yocB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389796.1 2086743 R 224308 CDS NP_389797.1 16078976 939666 2087696..2088193 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2088193 yocC 939666 yocC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389797.1 2087696 D 224308 CDS NP_389798.1 16078977 939659 2088257..2089234 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; carboxypeptidase YocD 2089234 yocD 939659 yocD Bacillus subtilis subsp. subtilis str. 168 carboxypeptidase YocD NP_389798.1 2088257 D 224308 CDS NP_389799.1 16078978 939668 2089396..2090454 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12207704, 15247225, 15711796, 16105701; Product type e: enzyme; fatty acid desaturase 2090454 des 939668 des Bacillus subtilis subsp. subtilis str. 168 fatty acid desaturase NP_389799.1 2089396 D 224308 CDS NP_389800.1 16078979 939678 2090574..2091686 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type rc : receptor; sensor histidine kinase 2091686 desK 939678 desK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_389800.1 2090574 D 224308 CDS NP_389801.1 16078980 939664 2091705..2092304 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11285232, 11717295, 12207704, 14734164, 15090506, 15711796; Product type r : regulator; transcriptional regulatory protein DesR 2092304 desR 939664 desR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein DesR NP_389801.1 2091705 D 224308 CDS NP_389802.1 16078981 939673 complement(2092899..2093762) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17307850; Product type pf : factor; cell wall-binding protein YocH 2093762 yocH 939673 yocH Bacillus subtilis subsp. subtilis str. 168 cell wall-binding protein YocH NP_389802.1 2092899 R 224308 CDS NP_389803.1 16078982 939671 complement(2094010..2095785) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11886746; Product type pe : enzyme; ATP-dependent DNA helicase RecQ 2095785 yocI 939671 yocI Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA helicase RecQ NP_389803.1 2094010 R 224308 CDS NP_389804.1 16078983 939669 complement(2096350..2096976) 1 NC_000964.3 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; FMN-dependent NADH-azoreductase 1 2096976 yocJ 939669 yocJ Bacillus subtilis subsp. subtilis str. 168 FMN-dependent NADH-azoreductase 1 NP_389804.1 2096350 R 224308 CDS NP_389805.2 255767450 939676 complement(2097126..2097617) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166; Product type pf : factor; general stress protein 16O 2097617 yocK 939676 yocK Bacillus subtilis subsp. subtilis str. 168 general stress protein 16O NP_389805.2 2097126 R 224308 CDS NP_389806.1 16078985 939586 complement(2097692..2098024) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2098024 yocL 939586 yocL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389806.1 2097692 R 224308 CDS YP_003097740.1 255767451 8303149 2098102..2098329 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2098329 yoyB 8303149 yoyB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097740.1 2098102 D 224308 CDS NP_389808.1 16078986 939587 complement(2098316..2098792) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11150673; Product type ps : structure; hypothetical protein 2098792 yocM 939587 yocM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389808.1 2098316 R 224308 CDS NP_389809.1 16078987 939679 2098859..2099122 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2099122 yozN 939679 yozN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389809.1 2098859 D 224308 CDS NP_389810.1 16078988 939594 2099127..2099360 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2099360 yocN 939594 yocN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389810.1 2099127 D 224308 CDS NP_389811.1 16078989 939681 complement(2099446..2099790) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2099790 yozO 939681 yozO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389811.1 2099446 R 224308 CDS NP_389812.1 16078990 939998 complement(2100147..2100350) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2100350 yozC 939998 yozC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389812.1 2100147 R 224308 CDS NP_389813.1 16078991 939963 2100580..2102067 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase DhaS 2102067 dhaS 939963 dhaS Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase DhaS NP_389813.1 2100580 D 224308 CDS NP_389814.2 50812246 939443 2102168..2104066 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2253626; Product type e: enzyme; sporulenol synthase 2104066 sqhC 939443 sqhC Bacillus subtilis subsp. subtilis str. 168 sporulenol synthase NP_389814.2 2102168 D 224308 CDS NP_389815.1 16078993 939503 2104056..2104901 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; superoxide dismutase 2104901 sodF 939503 sodF Bacillus subtilis subsp. subtilis str. 168 superoxide dismutase NP_389815.1 2104056 D 224308 CDS NP_389816.1 16078994 939450 complement(2104934..2106271) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YocR 2106271 yocR 939450 yocR Bacillus subtilis subsp. subtilis str. 168 sodium-dependent transporter YocR NP_389816.1 2104934 R 224308 CDS NP_389817.1 16078995 939452 2106490..2107455 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sodium-dependent transporter YocS 2107455 yocS 939452 yocS Bacillus subtilis subsp. subtilis str. 168 sodium-dependent transporter YocS NP_389817.1 2106490 D 224308 CDS NP_389818.2 255767452 939505 complement(2107505..2108758) 1 NC_000964.3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA; dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex 2108758 odhB 939505 odhB Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex NP_389818.2 2107505 R 224308 CDS NP_389819.3 255767453 939507 complement(2108774..2111608) 1 NC_000964.3 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 2111608 sucA 939507 sucA Bacillus subtilis subsp. subtilis str. 168 2-oxoglutarate dehydrogenase E1 component NP_389819.3 2108774 R 224308 CDS NP_389820.2 255767454 939499 complement(2111837..2113753) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2113753 yojO 939499 yojO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389820.2 2111837 R 224308 CDS NP_389821.1 16078999 939458 complement(2113764..2114678) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15491156; Product type pe : enzyme; hypothetical protein 2114678 yojN 939458 yojN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389821.1 2113764 R 224308 CDS NP_389822.1 16079000 939502 complement(2114742..2115332) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15897454; Product type lp: lipoprotein; superoxide dismutase-like protein YojM 2115332 sodC 939502 sodC Bacillus subtilis subsp. subtilis str. 168 superoxide dismutase-like protein YojM NP_389822.1 2114742 R 224308 CDS NP_389823.1 16079001 939459 complement(2115425..2116669) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16855244; Product type e: enzyme; D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS 2116669 cwlS 939459 cwlS Bacillus subtilis subsp. subtilis str. 168 D-gamma-glutamyl-meso-diaminopimelic acid endopeptidase CwlS NP_389823.1 2115425 R 224308 CDS NP_389824.2 50812248 939457 complement(2117051..2118268) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucosyltransferase YojK 2118268 yojK 939457 yojK Bacillus subtilis subsp. subtilis str. 168 UDP-glucosyltransferase YojK NP_389824.2 2117051 R 224308 CDS NP_389825.3 255767455 939589 complement(2118504..2119127) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2119127 yojJ 939589 yojJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389825.3 2118504 R 224308 CDS NP_389826.1 16079004 939592 2119393..2120751 1 NC_000964.3 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones; multidrug resistance protein NorM 2120751 yojI 939592 yojI Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NorM NP_389826.1 2119393 D 224308 CDS NP_389827.1 16079005 940093 2120767..2121615 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 17158665; Product type f: factor; RsbT co-antagonist protein RsbRC 2121615 rsbRC 940093 rsbRC Bacillus subtilis subsp. subtilis str. 168 RsbT co-antagonist protein RsbRC NP_389827.1 2120767 D 224308 CDS YP_054582.2 255767456 2914250 complement(2121641..2122306) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15136574; Product type pe : enzyme; deacetylase YojG 2122306 yojG 2914250 yojG Bacillus subtilis subsp. subtilis str. 168 deacetylase YojG YP_054582.2 2121641 R 224308 CDS NP_389829.1 16079006 939590 complement(2122325..2122675) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2122675 yojF 939590 yojF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389829.1 2122325 R 224308 CDS YP_003097741.1 255767457 8303009 complement(2122672..2122950) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2122950 yoyC 8303009 yoyC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097741.1 2122672 R 224308 CDS NP_389830.2 50812251 939447 complement(2123026..2123922) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; transporter 2123922 yojE 939447 yojE Bacillus subtilis subsp. subtilis str. 168 transporter NP_389830.2 2123026 R 224308 CDS YP_054583.1 50812252 2914248 2124021..2124494 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17720779; Product type s: structure; spore germination protein GerT 2124494 gerT 2914248 gerT Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerT YP_054583.1 2124021 D 224308 CDS NP_389832.1 16079009 939446 complement(2124529..2124765) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2124765 yojB 939446 yojB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389832.1 2124529 R 224308 CDS NP_389833.1 16079010 939510 complement(2124850..2126184) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 3020045; Product type pt: transporter; permease YojA 2126184 yojA 939510 yojA Bacillus subtilis subsp. subtilis str. 168 permease YojA NP_389833.1 2124850 R 224308 CDS NP_389834.1 16079011 939461 2126549..2126938 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YolI 2126938 yodA 939461 yodA Bacillus subtilis subsp. subtilis str. 168 tautomerase YolI NP_389834.1 2126549 D 224308 CDS NP_389835.1 16079012 939449 complement(2127345..2127683) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17158660, 18208493; Product type r: regulator; ArsR family transcriptional regulator 2127683 yodB 939449 yodB Bacillus subtilis subsp. subtilis str. 168 ArsR family transcriptional regulator NP_389835.1 2127345 R 224308 CDS NP_389836.1 16079013 939506 2127813..2128421 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H nitroreductase 2128421 yodC 939506 yodC Bacillus subtilis subsp. subtilis str. 168 NAD(P)H nitroreductase NP_389836.1 2127813 D 224308 CDS NP_389837.1 16079014 940106 complement(2128464..2129066) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; hydrolase MhqD 2129066 yodD 940106 yodD Bacillus subtilis subsp. subtilis str. 168 hydrolase MhqD NP_389837.1 2128464 R 224308 CDS NP_389838.1 16079015 940022 complement(2129082..2129993) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17407181; Product type pe : enzyme; ring-cleaving dioxygenase MhqE 2129993 yodE 940022 yodE Bacillus subtilis subsp. subtilis str. 168 ring-cleaving dioxygenase MhqE NP_389838.1 2129082 R 224308 CDS YP_003097742.1 255767458 8303187 2130177..2130377 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; membrane protein 2130377 yoyD 8303187 yoyD Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097742.1 2130177 D 224308 CDS NP_389839.1 16079016 940028 2130377..2131867 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12823818, 15849754, 16850406; Product type pt: transporter; symporter 2131867 yodF 940028 yodF Bacillus subtilis subsp. subtilis str. 168 symporter NP_389839.1 2130377 D 224308 CDS NP_389840.1 16079017 940115 complement(2131902..2133302) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10974125, 14526016, 8996100; Product type e : enzyme; carboxy-terminal processing protease CtpA 2133302 ctpA 940115 ctpA Bacillus subtilis subsp. subtilis str. 168 carboxy-terminal processing protease CtpA NP_389840.1 2131902 R 224308 CDS NP_389841.1 16079018 940101 2133455..2134156 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; methyltransferase 2134156 yodH 940101 yodH Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_389841.1 2133455 D 224308 CDS NP_389842.1 16079019 940039 2134244..2134495 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2134495 yodI 940039 yodI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389842.1 2134244 D 224308 CDS NP_389843.1 16079020 940023 complement(2134566..2135387) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15187182, 8631706; Product type e: enzyme; carboxypeptidase YodJ 2135387 yodJ 940023 yodJ Bacillus subtilis subsp. subtilis str. 168 carboxypeptidase YodJ NP_389843.1 2134566 R 224308 CDS NP_389844.1 16079021 940038 complement(2135470..2136171) 1 NC_000964.3 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase DeoD-type 2136171 deoD 940038 deoD Bacillus subtilis subsp. subtilis str. 168 purine nucleoside phosphorylase DeoD-type NP_389844.1 2135470 R 224308 CDS YP_003097743.1 255767459 8303105 2136373..2136498 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2136498 yoyE 8303105 yoyE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097743.1 2136373 D 224308 CDS NP_389845.2 255767460 940030 complement(2136538..2136852) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2136852 yodL 940030 yodL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389845.2 2136538 R 224308 CDS NP_389846.1 16079023 940034 complement(2136913..2137524) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; lipid phosphate phosphatase YodM 2137524 yodM 940034 yodM Bacillus subtilis subsp. subtilis str. 168 lipid phosphate phosphatase YodM NP_389846.1 2136913 R 224308 CDS NP_389847.1 16079024 940042 complement(2137602..2137778) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2137778 yozD 940042 yozD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389847.1 2137602 R 224308 CDS YP_003097744.1 255767461 8303015 2137897..2138040 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 2138040 yoyF 8303015 yoyF Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097744.1 2137897 D 224308 CDS NP_389848.1 16079025 940037 complement(2138037..2138717) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2138717 yodN 940037 yodN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389848.1 2138037 R 224308 CDS NP_389849.1 16079026 940055 complement(2138868..2139092) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2139092 yozE 940055 yozE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389849.1 2138868 R 224308 CDS YP_003097745.1 255767462 8303010 complement(2139179..2139457) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2139457 yokU 8303010 yokU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097745.1 2139179 R 224308 CDS NP_389850.1 16079027 940040 complement(2139454..2140869) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629195, 10839984, 11148055, 18307109; Product type e: enzyme; L-lysine 2,3-aminomutase 2140869 kamA 940040 kamA Bacillus subtilis subsp. subtilis str. 168 L-lysine 2,3-aminomutase NP_389850.1 2139454 R 224308 CDS NP_389851.1 16079028 940057 complement(2140898..2141725) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YodP 2141725 yodP 940057 yodP Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YodP NP_389851.1 2140898 R 224308 CDS NP_389852.1 16079029 940044 complement(2141703..2143013) 1 NC_000964.3 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine; metallohydrolase YodQ 2143013 yodQ 940044 yodQ Bacillus subtilis subsp. subtilis str. 168 metallohydrolase YodQ NP_389852.1 2141703 R 224308 CDS NP_389853.1 16079030 940048 complement(2143022..2143675) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; coenzyme A transferase subunit beta 2143675 yodR 940048 yodR Bacillus subtilis subsp. subtilis str. 168 coenzyme A transferase subunit beta NP_389853.1 2143022 R 224308 CDS NP_389854.1 16079031 940052 complement(2143660..2144349) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; coenzyme A transferase subunit alpha 2144349 yodS 940052 yodS Bacillus subtilis subsp. subtilis str. 168 coenzyme A transferase subunit alpha NP_389854.1 2143660 R 224308 CDS NP_389855.1 16079032 940050 complement(2144356..2145690) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminotransferase YodT 2145690 yodT 940050 yodT Bacillus subtilis subsp. subtilis str. 168 aminotransferase YodT NP_389855.1 2144356 R 224308 CDS YP_003097746.1 255767463 8302971 complement(2145820..2145933) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2145933 yoyG 8302971 yoyG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097746.1 2145820 R 224308 CDS NP_389856.1 16079033 940064 complement(2146013..2146792) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; N-acetyltransferase CgeE 2146792 cgeE 940064 cgeE Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase CgeE NP_389856.1 2146013 R 224308 CDS NP_389857.1 16079034 940063 complement(2146821..2148101) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeD 2148101 cgeD 940063 cgeD Bacillus subtilis subsp. subtilis str. 168 spore maturation protein CgeD NP_389857.1 2146821 R 224308 CDS NP_389858.1 16079035 940074 complement(2148166..2148471) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeC 2148471 cgeC 940074 cgeC Bacillus subtilis subsp. subtilis str. 168 spore maturation protein CgeC NP_389858.1 2148166 R 224308 CDS NP_389859.1 16079036 940066 2148676..2149077 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14702409, 15621419, 759239; Product type cp: cell process; spore maturation protein CgeA 2149077 cgeA 940066 cgeA Bacillus subtilis subsp. subtilis str. 168 spore maturation protein CgeA NP_389859.1 2148676 D 224308 CDS NP_389860.2 255767464 940061 2149084..2150037 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10066829, 1729246; Product type cp: cell process; spore maturation protein CgeB 2150037 cgeB 940061 cgeB Bacillus subtilis subsp. subtilis str. 168 spore maturation protein CgeB NP_389860.2 2149084 D 224308 CDS NP_389861.1 16079038 940065 complement(2150108..2151256) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10679209, 12111145, 12556126; Product type e: enzyme; 3-phytase 2151256 phy 940065 phy Bacillus subtilis subsp. subtilis str. 168 3-phytase NP_389861.1 2150108 R 224308 CDS NP_389863.1 16079040 940072 complement(2152086..2152262) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein 2152262 yotN 940072 yotN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389863.1 2152086 R 224308 CDS NP_389864.1 16079041 940081 complement(2152265..2152852) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; Product type h : extrachromosomal origin; hypothetical protein 2152852 yotM 940081 yotM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389864.1 2152265 R 224308 CDS NP_389865.1 16079042 940077 2152927..2153169 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; XRE family transcriptional regulator 2153169 yotL 940077 yotL Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389865.1 2152927 D 224308 CDS NP_389866.1 16079043 939549 complement(2153171..2153356) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2153356 yotK 939549 yotK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389866.1 2153171 R 224308 CDS NP_389867.1 16079044 940079 complement(2153440..2153652) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2153652 yotJ 940079 yotJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389867.1 2153440 R 224308 CDS NP_389868.1 16079045 940078 complement(2153718..2154080) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2154080 yotI 940078 yotI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389868.1 2153718 R 224308 CDS NP_389869.1 16079046 940084 complement(2154077..2154250) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 2154250 yotH 940084 yotH Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389869.1 2154077 R 224308 CDS NP_389870.1 16079047 940082 complement(2154266..2154583) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2154583 yotG 940082 yotG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389870.1 2154266 R 224308 CDS NP_389871.1 16079048 940086 complement(2154596..2154673) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2154673 yotF 940086 yotF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389871.1 2154596 R 224308 CDS NP_389872.1 16079049 939566 complement(2154705..2154851) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2154851 yotE 939566 yotE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389872.1 2154705 R 224308 CDS NP_389873.1 16079050 940092 complement(2154887..2155018) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2155018 yotD 940092 yotD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389873.1 2154887 R 224308 CDS NP_389874.1 16079051 940094 complement(2155058..2155249) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2155249 yotC 940094 yotC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389874.1 2155058 R 224308 CDS NP_389875.1 16079052 940114 complement(2155293..2156120) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2156120 yotB 940114 yotB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389875.1 2155293 R 224308 CDS NP_389876.1 16079053 939473 2156239..2156457 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 12234173, 14526021, 15150240; Product type s: structure; small acid-soluble spore protein C 2156457 sspC 939473 sspC Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein C NP_389876.1 2156239 D 224308 CDS NP_389878.1 16079055 939517 complement(2156757..2157110) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2157110 yosX 939517 yosX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389878.1 2156757 R 224308 CDS NP_389879.1 16079056 938813 complement(2157341..2157682) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2157682 yosW 938813 yosW Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389879.1 2157341 R 224308 CDS NP_389880.1 16079057 939523 complement(2157829..2158119) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2158119 yosV 939523 yosV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389880.1 2157829 R 224308 CDS YP_003097747.1 255767465 8302977 complement(2158120..2158287) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2158287 yojW 8302977 yojW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097747.1 2158120 R 224308 CDS NP_389881.1 16079058 939552 2158439..2158684 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2158684 yosU 939552 yosU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389881.1 2158439 D 224308 CDS NP_389882.1 16079059 939471 complement(2158724..2159173) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator YosT 2159173 yosT 939471 yosT Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator YosT NP_389882.1 2158724 R 224308 CDS NP_389883.1 16079060 939536 complement(2159268..2159696) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11375514, 15939294; Product type h: extrachromosomal origin; deoxyuridine 5'-triphosphate nucleotidohydrolase YosS 2159696 yosS 939536 yosS Bacillus subtilis subsp. subtilis str. 168 deoxyuridine 5'-triphosphate nucleotidohydrolase YosS NP_389883.1 2159268 R 224308 CDS NP_389884.1 16079061 939513 complement(2159742..2159984) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15937154, 16885274, 17395719; Product type h: extrachromosomal origin; thioredoxin 2159984 yosR 939513 yosR Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_389884.1 2159742 R 224308 CDS NP_389886.2 50812253 939476 complement(join(2159981..2160388,2161197..2161778)) 1 NC_000964.3 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleoside-diphosphate reductase subunit beta 2161778 nrdF 939476 nrdF Bacillus subtilis subsp. subtilis str. 168 ribonucleoside-diphosphate reductase subunit beta NP_389886.2 2159981 R 224308 CDS NP_389885.1 16079062 939514 complement(2160565..2161086) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type h: extrachromosomal origin; HNH homing endonuclease YosQ 2161086 yosQ 939514 yosQ Bacillus subtilis subsp. subtilis str. 168 HNH homing endonuclease YosQ NP_389885.1 2160565 R 224308 CDS NP_389888.2 50812254 939475 complement(join(2162108..2164642,2164895..2165614)) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11470879, 16621400, 17395719, 9465078; Product type e: enzyme; ribonucleoside-diphosphate reductase NrdEB subunit alpha 2165614 nrdEB 939475 nrdEB Bacillus subtilis subsp. subtilis str. 168 ribonucleoside-diphosphate reductase NrdEB subunit alpha NP_389888.2 2162108 R 224308 CDS NP_389889.1 16079066 939562 complement(2165577..2165966) 1 NC_000964.3 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; ribonucleotide reductase stimulatory protein NrdI 2165966 nrdI 939562 nrdI Bacillus subtilis subsp. subtilis str. 168 ribonucleotide reductase stimulatory protein NrdI NP_389889.1 2165577 R 224308 CDS NP_389890.1 16079067 939559 complement(2165972..2166325) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2166325 yosL 939559 yosL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389890.1 2165972 R 224308 CDS NP_389891.1 16079068 939546 complement(2166413..2166613) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2166613 yosK 939546 yosK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389891.1 2166413 R 224308 CDS NP_389892.1 16079069 939556 complement(2166658..2166852) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2166852 yosJ 939556 yosJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389892.1 2166658 R 224308 CDS NP_389893.1 16079070 939563 complement(2166873..2167007) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2167007 yosI 939563 yosI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389893.1 2166873 R 224308 CDS NP_389894.1 16079071 939551 complement(2167039..2167509) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2167509 yosH 939551 yosH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389894.1 2167039 R 224308 CDS NP_389895.1 16079072 939570 complement(2167570..2167932) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2167932 yosG 939570 yosG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389895.1 2167570 R 224308 CDS NP_389896.1 16079073 939526 complement(2167975..2168100) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2168100 yosF 939526 yosF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389896.1 2167975 R 224308 CDS NP_389897.1 16079074 939572 complement(2168114..2168461) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 2168461 yosE 939572 yosE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_389897.1 2168114 R 224308 CDS NP_389898.1 16079075 939554 complement(2168476..2168871) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2168871 yosD 939554 yosD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389898.1 2168476 R 224308 CDS NP_389899.1 16079076 939561 complement(2168910..2169452) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2169452 yosC 939561 yosC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389899.1 2168910 R 224308 CDS NP_389900.1 16079077 939568 complement(2169497..2169676) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2169676 yosB 939568 yosB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389900.1 2169497 R 224308 CDS NP_389901.1 16079078 939574 2169807..2169926 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; Product type h: extrachromosomal origin; hypothetical protein 2169926 yosA 939574 yosA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389901.1 2169807 D 224308 CDS NP_389902.1 16079079 939577 complement(2170030..2170242) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2170242 yorZ 939577 yorZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389902.1 2170030 R 224308 CDS NP_389903.1 16079080 939519 complement(2170309..2170491) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2170491 yorY 939519 yorY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389903.1 2170309 R 224308 CDS NP_389904.1 16079081 939737 complement(2170504..2170731) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2170731 yorX 939737 yorX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389904.1 2170504 R 224308 CDS NP_389905.1 16079082 939522 complement(2170771..2171136) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2171136 yorW 939522 yorW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389905.1 2170771 R 224308 CDS NP_389906.1 16079083 939579 complement(2171139..2171357) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 2171357 yorV 939579 yorV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389906.1 2171139 R 224308 CDS NP_389907.1 16079084 939532 complement(2171401..2172732) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type h: extrachromosomal origin; Phi-3T prophage-derived modification methylase Phi3TI 2172732 mtbP 939532 mtbP Bacillus subtilis subsp. subtilis str. 168 Phi-3T prophage-derived modification methylase Phi3TI NP_389907.1 2171401 R 224308 CDS NP_389908.1 16079085 939525 complement(2172781..2172900) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 2172900 yorT 939525 yorT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389908.1 2172781 R 224308 CDS NP_389909.1 16079086 939520 complement(2172932..2173450) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; 5'(3')-deoxyribonucleotidase 2173450 yorS 939520 yorS Bacillus subtilis subsp. subtilis str. 168 5'(3')-deoxyribonucleotidase NP_389909.1 2172932 R 224308 CDS NP_389910.1 16079087 939530 complement(2173459..2173956) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2173956 yorR 939530 yorR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389910.1 2173459 R 224308 CDS NP_389911.1 16079088 939534 complement(2173956..2174111) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2174111 yorQ 939534 yorQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389911.1 2173956 R 224308 CDS NP_389912.1 16079089 939535 complement(2174104..2174319) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2174319 yorP 939535 yorP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389912.1 2174104 R 224308 CDS NP_389913.1 16079090 939542 complement(2174352..2174549) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2174549 yorO 939542 yorO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389913.1 2174352 R 224308 CDS NP_389914.1 16079091 939538 complement(2174585..2174734) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2174734 yorN 939538 yorN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389914.1 2174585 R 224308 CDS NP_389915.1 16079092 939539 complement(2174852..2175568) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2175568 yorM 939539 yorM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389915.1 2174852 R 224308 CDS NP_389916.1 16079093 939437 complement(2175596..2179513) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; DNA polymerase YorL 2179513 yorL 939437 yorL Bacillus subtilis subsp. subtilis str. 168 DNA polymerase YorL NP_389916.1 2175596 R 224308 CDS NP_389917.1 16079094 939545 complement(2179526..2181256) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; single-strand DNA-specific exonuclease YorK 2181256 yorK 939545 yorK Bacillus subtilis subsp. subtilis str. 168 single-strand DNA-specific exonuclease YorK NP_389917.1 2179526 R 224308 CDS NP_389918.1 16079095 939584 complement(2181256..2182392) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2182392 yorJ 939584 yorJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389918.1 2181256 R 224308 CDS NP_389919.1 16079096 939707 complement(2182408..2183922) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2183922 yorI 939707 yorI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389919.1 2182408 R 224308 CDS NP_389920.1 16079097 939851 complement(2183937..2184407) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2184407 yorH 939851 yorH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389920.1 2183937 R 224308 CDS NP_389921.1 16079098 939865 complement(2184450..2185421) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2185421 yorG 939865 yorG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389921.1 2184450 R 224308 CDS NP_389922.1 16079099 940146 complement(2185504..2186418) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2186418 yorF 940146 yorF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389922.1 2185504 R 224308 CDS NP_389923.1 16079100 940144 complement(2186440..2186811) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2186811 yorE 940144 yorE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389923.1 2186440 R 224308 CDS NP_389924.1 16079101 940145 complement(2186985..2187299) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; stress response protein SCP1 2187299 yorD 940145 yorD Bacillus subtilis subsp. subtilis str. 168 stress response protein SCP1 NP_389924.1 2186985 R 224308 CDS NP_389925.1 16079102 936462 complement(2187376..2187756) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2187756 yorC 936462 yorC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389925.1 2187376 R 224308 CDS NP_389926.1 16079103 939951 complement(2187819..2188115) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2188115 yorB 939951 yorB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389926.1 2187819 R 224308 CDS NP_389927.1 16079104 940009 complement(2188204..2189964) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2189964 yorA 940009 yorA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389927.1 2188204 R 224308 CDS NP_389928.1 16079105 939582 complement(2189961..2190785) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2190785 yoqZ 939582 yoqZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389928.1 2189961 R 224308 CDS NP_389929.1 16079106 939509 complement(2190884..2191279) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2191279 yoqY 939509 yoqY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389929.1 2190884 R 224308 CDS NP_389930.1 16079107 939597 complement(2191334..2191555) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2191555 yoqX 939597 yoqX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389930.1 2191334 R 224308 CDS NP_389931.1 16079108 939979 2191626..2192300 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2192300 yoqW 939979 yoqW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389931.1 2191626 D 224308 CDS NP_389932.1 16079109 939992 2192370..2193182 1 NC_000964.3 catalyzes the ATP-dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; DNA ligase-like protein LigB 2193182 ligB 939992 ligB Bacillus subtilis subsp. subtilis str. 168 DNA ligase-like protein LigB NP_389932.1 2192370 D 224308 CDS NP_389933.1 16079110 940143 complement(2193248..2193661) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2193661 yoqU 940143 yoqU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389933.1 2193248 R 224308 CDS NP_389934.1 16079111 939616 2193827..2193976 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2193976 yoqT 939616 yoqT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389934.1 2193827 D 224308 CDS NP_389935.1 16079112 939995 complement(2194053..2194400) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2194400 yoqS 939995 yoqS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389935.1 2194053 R 224308 CDS NP_389936.1 16079113 939440 complement(2194402..2194758) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2194758 yoqR 939440 yoqR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389936.1 2194402 R 224308 CDS NP_389937.1 16079114 939583 complement(2194718..2195059) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2195059 yoqP 939583 yoqP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389937.1 2194718 R 224308 CDS NP_389938.1 16079115 936492 2195173..2195547 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2195547 yoqO 936492 yoqO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389938.1 2195173 D 224308 CDS NP_389939.1 16079116 936507 complement(2195564..2195782) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2195782 yoqN 936507 yoqN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389939.1 2195564 R 224308 CDS NP_389940.1 16079117 939973 2195986..2196264 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 2196264 yoqM 939973 yoqM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389940.1 2195986 D 224308 CDS NP_389941.1 16079118 939974 complement(2196389..2197081) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; HNH endonuclease YoqL 2197081 yoqL 939974 yoqL Bacillus subtilis subsp. subtilis str. 168 HNH endonuclease YoqL NP_389941.1 2196389 R 224308 CDS NP_389942.1 16079119 940015 complement(2197121..2197324) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2197324 yoqK 940015 yoqK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389942.1 2197121 R 224308 CDS NP_389943.1 16079120 939585 complement(2197344..2197859) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2197859 yoqJ 939585 yoqJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389943.1 2197344 R 224308 CDS NP_389944.1 16079121 939965 complement(2198070..2198264) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2198264 yoqI 939965 yoqI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389944.1 2198070 R 224308 CDS NP_389945.1 16079122 939438 complement(2198313..2198765) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2198765 yoqH 939438 yoqH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389945.1 2198313 R 224308 CDS NP_389946.1 16079123 936494 complement(2198848..2199105) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2199105 yoqG 936494 yoqG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389946.1 2198848 R 224308 CDS NP_389947.1 16079124 936493 complement(2199150..2199353) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2199353 yoqF 936493 yoqF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389947.1 2199150 R 224308 CDS NP_389948.1 16079125 939433 complement(2199362..2199526) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2199526 yoqE 939433 yoqE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389948.1 2199362 R 224308 CDS NP_389949.1 16079126 939436 complement(2199580..2200335) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 2661831; Product type pr : regulator; antirepressor protein YoqD 2200335 yoqD 939436 yoqD Bacillus subtilis subsp. subtilis str. 168 antirepressor protein YoqD NP_389949.1 2199580 R 224308 CDS NP_389950.1 16079127 936489 complement(2200376..2200783) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 2200783 yoqC 936489 yoqC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389950.1 2200376 R 224308 CDS NP_389951.1 16079128 939431 complement(2200790..2201128) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2201128 yoqB 939431 yoqB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389951.1 2200790 R 224308 CDS NP_389952.1 16079129 939434 complement(2201125..2201475) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2201475 yoqA 939434 yoqA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389952.1 2201125 R 224308 CDS NP_389953.1 16079130 936487 complement(2201488..2201691) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2201691 yopZ 936487 yopZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389953.1 2201488 R 224308 CDS NP_389954.1 16079131 936488 complement(2201705..2201983) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2201983 yopY 936488 yopY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389954.1 2201705 R 224308 CDS NP_389955.1 16079132 939430 complement(2201980..2202384) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2202384 yopX 939430 yopX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389955.1 2201980 R 224308 CDS NP_389956.1 16079133 936484 complement(2202381..2202716) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2202716 yopW 936484 yopW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389956.1 2202381 R 224308 CDS NP_389957.1 16079134 939432 complement(2202805..2202999) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2202999 yopV 939432 yopV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389957.1 2202805 R 224308 CDS NP_389958.1 16079135 936485 complement(2203111..2203308) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2203308 yopU 936485 yopU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389958.1 2203111 R 224308 CDS NP_389959.1 16079136 939424 complement(2203378..2203596) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2203596 yopT 939424 yopT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389959.1 2203378 R 224308 CDS NP_389960.1 16079137 939428 2203779..2204003 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2204003 yopS 939428 yopS Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389960.1 2203779 D 224308 CDS NP_389961.2 255767466 936483 complement(2204192..2205169) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2205169 yopR 936483 yopR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389961.2 2204192 R 224308 CDS NP_389962.1 16079139 936481 complement(2205193..2206575) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2206575 yopQ 936481 yopQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389962.1 2205193 R 224308 CDS NP_389963.1 16079140 936482 complement(2206682..2207758) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11208805; Product type pe : enzyme; integrase/recombinase YopP 2207758 yopP 936482 yopP Bacillus subtilis subsp. subtilis str. 168 integrase/recombinase YopP NP_389963.1 2206682 R 224308 CDS NP_389964.1 16079141 939435 complement(2207748..2207960) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2207960 yopO 939435 yopO Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389964.1 2207748 R 224308 CDS NP_389965.1 16079142 935916 complement(2208008..2208325) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2208325 yopN 935916 yopN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389965.1 2208008 R 224308 CDS NP_389966.1 16079143 939186 complement(2208328..2208528) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2208528 yopM 939186 yopM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389966.1 2208328 R 224308 CDS NP_389967.1 16079144 939422 complement(2208855..2208980) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2208980 yopL 939422 yopL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389967.1 2208855 R 224308 CDS NP_389968.1 16079145 939187 complement(2208994..2210154) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2210154 yopK 939187 yopK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389968.1 2208994 R 224308 CDS NP_389969.1 16079146 939184 complement(2210331..2210747) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 2210747 yopJ 939184 yopJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389969.1 2210331 R 224308 CDS NP_389970.1 16079147 939182 complement(2210749..2211282) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2211282 yopI 939182 yopI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389970.1 2210749 R 224308 CDS NP_389971.1 16079148 939185 complement(2211309..2211845) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2211845 yopH 939185 yopH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389971.1 2211309 R 224308 CDS NP_389972.1 16079149 939181 complement(2211884..2212015) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2212015 yopG 939181 yopG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389972.1 2211884 R 224308 CDS NP_389973.1 16079150 939179 complement(2212026..2212241) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2212241 yopF 939179 yopF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389973.1 2212026 R 224308 CDS NP_389974.1 16079151 939183 complement(2212245..2212496) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2212496 yopE 939183 yopE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389974.1 2212245 R 224308 CDS YP_003097748.1 255767467 8303201 2212567..2212746 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2212746 yoyH 8303201 yoyH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097748.1 2212567 D 224308 CDS YP_003097749.1 255767468 8302920 2212848..2213078 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2213078 yoyI 8302920 yoyI Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097749.1 2212848 D 224308 CDS NP_389976.1 16079152 939180 complement(2213083..2213478) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2213478 yopD 939180 yopD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389976.1 2213083 R 224308 CDS NP_389977.1 16079153 939177 complement(2213536..2214864) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2214864 yopC 939177 yopC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389977.1 2213536 R 224308 CDS NP_389978.1 16079154 939178 complement(2214972..2215199) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2215199 yopB 939178 yopB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389978.1 2214972 R 224308 CDS NP_389979.1 16079155 939175 complement(2215460..2216776) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2216776 yopA 939175 yopA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389979.1 2215460 R 224308 CDS NP_389980.1 16079156 939173 complement(2217133..2217639) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2217639 yonX 939173 yonX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389980.1 2217133 R 224308 CDS NP_389981.1 16079157 939174 complement(2217967..2219199) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2219199 yonV 939174 yonV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389981.1 2217967 R 224308 CDS NP_389982.1 16079158 939176 complement(2219281..2219469) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2219469 yonU 939176 yonU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389982.1 2219281 R 224308 CDS YP_003097750.1 255767469 8303210 complement(2219514..2219765) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 2219765 yoyJ 8303210 yoyJ Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097750.1 2219514 R 224308 CDS NP_389983.1 16079159 939172 complement(2219784..2219960) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2219960 yonT 939172 yonT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389983.1 2219784 R 224308 CDS NP_389984.1 16079160 939171 complement(2220335..2220946) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoprotein 2220946 yonS 939171 yonS Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_389984.1 2220335 R 224308 CDS NP_389985.1 16079161 939169 complement(2221061..2221387) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2221387 yonR 939169 yonR Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_389985.1 2221061 R 224308 CDS NP_389986.1 16079162 939168 2222340..2222534 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2222534 yonP 939168 yonP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389986.1 2222340 D 224308 CDS NP_389987.1 16079163 939167 2222574..2225093 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2225093 yonO 939167 yonO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389987.1 2222574 D 224308 CDS NP_389988.1 16079164 939170 2225337..2225615 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein HU 2 2225615 yonN 939170 yonN Bacillus subtilis subsp. subtilis str. 168 DNA-binding protein HU 2 NP_389988.1 2225337 D 224308 CDS NP_389989.1 16079165 939166 2227297..2227488 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2227488 yonK 939166 yonK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389989.1 2227297 D 224308 CDS NP_389990.2 255767470 939163 2227505..2228722 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2228722 yonJ 939163 yonJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389990.2 2227505 D 224308 CDS NP_389991.1 16079167 939164 complement(2228756..2229166) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2229166 yonI 939164 yonI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389991.1 2228756 R 224308 CDS NP_389992.1 16079168 939160 2229385..2229885 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2229885 yonH 939160 yonH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389992.1 2229385 D 224308 CDS NP_389993.1 16079169 939165 2229988..2230908 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2230908 yonG 939165 yonG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389993.1 2229988 D 224308 CDS NP_389994.1 16079170 939161 2230895..2232664 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774886; Product type pe : enzyme; hypothetical protein 2232664 yonF 939161 yonF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389994.1 2230895 D 224308 CDS NP_389995.1 16079171 939162 2232682..2234202 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2234202 yonE 939162 yonE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389995.1 2232682 D 224308 CDS NP_389996.1 16079172 939159 2234233..2235669 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2235669 yonD 939159 yonD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389996.1 2234233 D 224308 CDS NP_389997.1 16079173 939157 2235694..2236230 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2236230 yonC 939157 yonC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389997.1 2235694 D 224308 CDS NP_389998.1 16079174 939155 2236269..2237285 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2237285 yonB 939155 yonB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389998.1 2236269 D 224308 CDS NP_389999.1 16079175 939158 2237321..2237791 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2237791 yonA 939158 yonA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_389999.1 2237321 D 224308 CDS NP_390000.1 16079176 939156 2237806..2238201 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2238201 yomZ 939156 yomZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390000.1 2237806 D 224308 CDS NP_390001.1 16079177 939154 2238198..2238452 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2238452 yomY 939154 yomY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390001.1 2238198 D 224308 CDS NP_390002.1 16079178 939153 2238436..2239086 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2239086 yomX 939153 yomX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390002.1 2238436 D 224308 CDS NP_390003.1 16079179 939150 2239083..2239589 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2239589 yomW 939150 yomW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390003.1 2239083 D 224308 CDS NP_390004.1 16079180 939149 2239586..2240296 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2240296 yomV 939149 yomV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390004.1 2239586 D 224308 CDS NP_390005.1 16079181 939146 2240339..2241136 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2241136 yomU 939146 yomU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390005.1 2240339 D 224308 CDS YP_003097751.1 255767471 8302922 2241154..2241765 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2241765 youA 8302922 youA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097751.1 2241154 D 224308 CDS NP_390006.1 16079182 939151 2241765..2241992 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2241992 yomT 939151 yomT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390006.1 2241765 D 224308 CDS NP_390007.1 16079183 939152 2242056..2242412 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2242412 yomS 939152 yomS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390007.1 2242056 D 224308 CDS NP_390008.1 16079184 939147 2242414..2243631 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2243631 yomR 939147 yomR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390008.1 2242414 D 224308 CDS NP_390009.1 16079185 939142 2243642..2243992 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2243992 yomQ 939142 yomQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390009.1 2243642 D 224308 CDS NP_390010.1 16079186 939148 2243989..2244180 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2244180 yomP 939148 yomP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390010.1 2243989 D 224308 CDS NP_390011.1 16079187 939140 2244230..2244730 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2244730 yomO 939140 yomO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390011.1 2244230 D 224308 CDS NP_390012.1 16079188 939144 2244714..2245133 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2245133 yomN 939144 yomN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390012.1 2244714 D 224308 CDS NP_390013.1 16079189 939145 2245147..2246148 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; recombinase-like protein YomM 2246148 yomM 939145 yomM Bacillus subtilis subsp. subtilis str. 168 recombinase-like protein YomM NP_390013.1 2245147 D 224308 CDS NP_390014.1 16079190 939141 complement(2246151..2246480) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2246480 yozP 939141 yozP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390014.1 2246151 R 224308 CDS NP_390015.1 16079191 939143 complement(2246656..2247342) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2247342 yomL 939143 yomL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390015.1 2246656 R 224308 CDS YP_003097752.1 255767472 8303116 complement(2247367..2247543) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276; hypothetical protein 2247543 youB 8303116 youB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097752.1 2247367 R 224308 CDS NP_390016.1 16079192 939137 2247889..2248335 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2248335 yomK 939137 yomK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390016.1 2247889 D 224308 CDS NP_390017.1 16079193 939133 2248417..2249100 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; membrane protein 2249100 yomJ 939133 yomJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390017.1 2248417 D 224308 CDS NP_390018.2 255767473 939138 2249154..2256011 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931330; Product type h: extrachromosomal origin; transglycosylase YomI 2256011 yomI 939138 yomI Bacillus subtilis subsp. subtilis str. 168 transglycosylase YomI NP_390018.2 2249154 D 224308 CDS NP_390019.1 16079195 939139 2256062..2256820 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2256820 yomH 939139 yomH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390019.1 2256062 D 224308 CDS NP_390020.1 16079196 939135 2256832..2259459 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; hypothetical protein 2259459 yomG 939135 yomG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390020.1 2256832 D 224308 CDS NP_390021.1 16079197 939134 2259475..2260296 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2260296 yomF 939134 yomF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390021.1 2259475 D 224308 CDS NP_390022.1 16079198 939136 2260333..2262267 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2262267 yomE 939136 yomE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390022.1 2260333 D 224308 CDS NP_390023.1 16079199 939131 2262437..2263261 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2263261 yomD 939131 yomD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390023.1 2262437 D 224308 CDS NP_390024.1 16079200 939130 2263489..2264592 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; N-acetylmuramoyl-L-alanine amidase BlyA 2264592 blyA 939130 blyA Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase BlyA NP_390024.1 2263489 D 224308 CDS NP_390025.1 16079201 939132 2264680..2264892 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type h: extrachromosomal origin; holin BhlA 2264892 bhlA 939132 bhlA Bacillus subtilis subsp. subtilis str. 168 holin BhlA NP_390025.1 2264680 D 224308 CDS NP_390026.1 16079202 939127 2264903..2265169 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 17322187; Product type h: extrachromosomal origin; holin-like bacteriophage SPbeta protein BhlB 2265169 bhlB 939127 bhlB Bacillus subtilis subsp. subtilis str. 168 holin-like bacteriophage SPbeta protein BhlB NP_390026.1 2264903 D 224308 CDS NP_390027.1 16079203 939128 complement(2265225..2265671) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16850406; Product type h: extrachromosomal origin; disulfide bond formation protein B 2265671 bdbB 939128 bdbB Bacillus subtilis subsp. subtilis str. 168 disulfide bond formation protein B NP_390027.1 2265225 R 224308 CDS NP_390028.1 16079204 939123 complement(2265668..2266936) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pe : enzyme; glycosyltransferase SunS 2266936 yolJ 939123 yolJ Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase SunS NP_390028.1 2265668 R 224308 CDS NP_390029.1 16079205 939129 complement(2266936..2267349) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949; Product type h: extrachromosomal origin; disulfide bond formation protein A 2267349 bdbA 939129 bdbA Bacillus subtilis subsp. subtilis str. 168 disulfide bond formation protein A NP_390029.1 2266936 R 224308 CDS NP_390030.1 16079206 939124 complement(2267346..2269463) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type t: transporter; sublancin-168-processing and transport ATP-binding protein SunT 2269463 sunT 939124 sunT Bacillus subtilis subsp. subtilis str. 168 sublancin-168-processing and transport ATP-binding protein SunT NP_390030.1 2267346 R 224308 CDS NP_390031.1 16079207 939121 complement(2269521..2269691) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 9722542; Product type h: extrachromosomal origin; bacteriocin sublancin-168 2269691 sunA 939121 sunA Bacillus subtilis subsp. subtilis str. 168 bacteriocin sublancin-168 NP_390031.1 2269521 R 224308 CDS NP_390032.1 16079208 939125 complement(2269988..2270305) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821, 19047653; Product type cp: cell process; hypothetical protein 2270305 sunI 939125 sunI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390032.1 2269988 R 224308 CDS NP_390033.2 255767474 939122 complement(2270407..2271657) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12137951, 12644484; Product type e : enzyme; UV-damage repair protein UvrX 2271657 uvrX 939122 uvrX Bacillus subtilis subsp. subtilis str. 168 UV-damage repair protein UvrX NP_390033.2 2270407 R 224308 CDS NP_390034.1 16079210 939126 complement(2271650..2271982) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951; hypothetical protein 2271982 yolD 939126 yolD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390034.1 2271650 R 224308 CDS NP_390035.1 16079211 939120 2272156..2272491 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376821; Product type h: extrachromosomal origin; hypothetical protein 2272491 yolC 939120 yolC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390035.1 2272156 D 224308 CDS NP_390036.1 16079212 939119 complement(2272534..2272890) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2272890 yolB 939119 yolB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390036.1 2272534 R 224308 CDS NP_390037.1 16079213 939117 complement(2272896..2273363) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; hypothetical protein 2273363 yolA 939117 yolA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390037.1 2272896 R 224308 CDS NP_390038.1 16079214 939118 complement(2273989..2274522) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YokL 2274522 yokL 939118 yokL Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YokL NP_390038.1 2273989 R 224308 CDS NP_390039.1 16079215 939116 complement(2274558..2275136) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2275136 yokK 939116 yokK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390039.1 2274558 R 224308 CDS NP_390040.1 16079216 939114 complement(2275200..2275697) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2275697 yokJ 939114 yokJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390040.1 2275200 R 224308 CDS NP_390041.2 255767475 939115 complement(2275706..2277421) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2277421 yokI 939115 yokI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390041.2 2275706 R 224308 CDS NP_390042.1 16079218 939111 complement(2277521..2278078) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2278078 yokH 939111 yokH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390042.1 2277521 R 224308 CDS NP_390043.1 16079219 939112 complement(2278602..2279675) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; pesticidal crystal protein-like YokG 2279675 yokG 939112 yokG Bacillus subtilis subsp. subtilis str. 168 pesticidal crystal protein-like YokG NP_390043.1 2278602 R 224308 CDS NP_390044.1 16079220 939113 2279977..2280867 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11584000; Product type h: extrachromosomal origin; endonuclease 2280867 yokF 939113 yokF Bacillus subtilis subsp. subtilis str. 168 endonuclease NP_390044.1 2279977 D 224308 CDS NP_390045.1 16079221 939108 2280881..2281363 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2281363 yokE 939108 yokE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390045.1 2280881 D 224308 CDS NP_390046.1 16079222 939106 2281667..2282485 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; aminoglycoside N(3')-acetyltransferase-like protein YokD 2282485 yokD 939106 yokD Bacillus subtilis subsp. subtilis str. 168 aminoglycoside N(3')-acetyltransferase-like protein YokD NP_390046.1 2281667 D 224308 CDS NP_390047.1 16079223 939109 complement(2283136..2283651) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10376821; hypothetical protein 2283651 yokC 939109 yokC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390047.1 2283136 R 224308 CDS NP_390048.1 16079224 939110 complement(2283858..2284568) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 10376821; lipoprotein 2284568 yokB 939110 yokB Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_390048.1 2283858 R 224308 CDS NP_390049.1 16079225 939105 2284771..2286408 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376821, 401505; Product type pe: enzyme; resolvase homolog YokA 2286408 yokA 939105 yokA Bacillus subtilis subsp. subtilis str. 168 resolvase homolog YokA NP_390049.1 2284771 D 224308 CDS NP_390051.1 16079227 939102 complement(2287097..2287528) 1 NC_000964.3 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress; peptide methionine sulfoxide reductase MsrB 2287528 yppQ 939102 yppQ Bacillus subtilis subsp. subtilis str. 168 peptide methionine sulfoxide reductase MsrB NP_390051.1 2287097 R 224308 CDS NP_390052.1 16079228 939099 complement(2287529..2288062) 1 NC_000964.3 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress; peptide methionine sulfoxide reductase MsrA 2288062 msrA 939099 msrA Bacillus subtilis subsp. subtilis str. 168 peptide methionine sulfoxide reductase MsrA NP_390052.1 2287529 R 224308 CDS NP_390053.1 16079229 939103 2288194..2288619 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809700, 9571784; Product type pr: regulator; MarR family transcriptional regulator 2288619 ypoP 939103 ypoP Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_390053.1 2288194 D 224308 CDS NP_390054.1 16079230 939104 complement(2288669..2290006) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11583854, 15849754, 16850406; Product type t : transporter; multidrug resistance protein 2290006 dinF 939104 dinF Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_390054.1 2288669 R 224308 CDS NP_390055.1 16079231 939101 complement(2290078..2290272) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2290272 ypmT 939101 ypmT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390055.1 2290078 R 224308 CDS NP_390056.1 16079232 939100 complement(2290285..2290848) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2290848 ypmS 939100 ypmS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390056.1 2290285 R 224308 CDS NP_390057.1 16079233 939097 complement(2290858..2291625) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2291625 ypmR 939097 ypmR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390057.1 2290858 R 224308 CDS NP_390058.2 255767476 939098 complement(2291703..2292284) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14680962, 14766920, 16305244, 19027886, 10837475; Product type f: factor; SCO1 protein homolog 2292284 scuA 939098 scuA Bacillus subtilis subsp. subtilis str. 168 SCO1 protein homolog NP_390058.2 2291703 R 224308 CDS NP_390059.1 16079235 939096 complement(2292432..2292683) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15060025; hypothetical protein 2292683 ypmP 939096 ypmP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390059.1 2292432 R 224308 CDS NP_390060.1 16079236 939093 complement(2292769..2294037) 1 NC_000964.3 catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 2294037 ilvA 939093 ilvA Bacillus subtilis subsp. subtilis str. 168 threonine dehydratase NP_390060.1 2292769 R 224308 CDS NP_390061.1 16079237 939094 2294286..2295281 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399512, 16585774; Product type r: regulator; sigma L-dependent transcriptional regulator YplP 2295281 yplP 939094 yplP Bacillus subtilis subsp. subtilis str. 168 sigma L-dependent transcriptional regulator YplP NP_390061.1 2294286 D 224308 CDS NP_390062.1 16079238 939095 2295302..2295943 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16585774, 16850406; Product type pe: enzyme; hemolysin-3 homolog 2295943 yplQ 939095 yplQ Bacillus subtilis subsp. subtilis str. 168 hemolysin-3 homolog NP_390062.1 2295302 D 224308 CDS NP_390063.2 255767477 939090 complement(2295982..2296602) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2296602 ypkP 939090 ypkP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390063.2 2295982 R 224308 CDS NP_390064.1 16079240 939091 complement(2296603..2297109) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10574451, 12682299, 2840350, 3918568; Product type e: enzyme; dihydrofolate reductase 2297109 dfrA 939091 dfrA Bacillus subtilis subsp. subtilis str. 168 dihydrofolate reductase NP_390064.1 2296603 R 224308 CDS NP_390065.1 16079241 939092 complement(2297106..2297900) 1 NC_000964.3 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 2297900 thyA 939092 thyA Bacillus subtilis subsp. subtilis str. 168 thymidylate synthase NP_390065.1 2297106 R 224308 CDS NP_390066.1 16079242 939087 complement(2297984..2298517) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8534098; Product type pe : enzyme; hypothetical protein 2298517 ypjQ 939087 ypjQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390066.1 2297984 R 224308 CDS NP_390067.1 16079243 939089 complement(2298535..2299146) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2299146 ypjP 939089 ypjP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390067.1 2298535 R 224308 CDS NP_390068.2 255767478 939088 complement(2299406..2300179) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2300179 ypiP 939088 ypiP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390068.2 2299406 R 224308 CDS NP_390069.1 16079245 939085 complement(2300221..2300655) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2300655 yphP 939085 yphP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390069.1 2300221 R 224308 CDS NP_390070.2 255767479 939084 complement(2300762..2302438) 1 NC_000964.3 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase 2302438 ilvD 939084 ilvD Bacillus subtilis subsp. subtilis str. 168 dihydroxy-acid dehydratase NP_390070.2 2300762 R 224308 CDS NP_390071.1 16079247 939082 complement(2302727..2303860) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2303860 ypgR 939082 ypgR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390071.1 2302727 R 224308 CDS NP_390072.1 16079248 939080 complement(2303920..2304537) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2304537 ypgQ 939080 ypgQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390072.1 2303920 R 224308 CDS NP_390073.1 16079249 939086 complement(2304553..2305035) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871, 14617062; Product type pe: enzyme; glutathione peroxidase homolog BsaA 2305035 bsaA 939086 bsaA Bacillus subtilis subsp. subtilis str. 168 glutathione peroxidase homolog BsaA NP_390073.1 2304553 R 224308 CDS NP_390074.2 255767480 939083 2305378..2306283 1 NC_000964.3 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase 2306283 metA 939083 metA Bacillus subtilis subsp. subtilis str. 168 homoserine O-succinyltransferase NP_390074.2 2305378 D 224308 CDS NP_390075.1 16079251 939081 2306514..2307662 1 NC_000964.3 processive; catalyzes the formation of mono-, di- and tri-glucosyldiacylglycerol by the progressive transfer of glucosyl residues to diacylglycerol; involved in the formation of membrane glycolipids; processive diacylglycerol glucosyltransferase 2307662 ugtP 939081 ugtP Bacillus subtilis subsp. subtilis str. 168 processive diacylglycerol glucosyltransferase NP_390075.1 2306514 D 224308 CDS NP_390076.1 16079252 939079 2307905..2308105 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16352840, 9920884; Product type f: factor; cold shock protein CspD 2308105 cspD 939079 cspD Bacillus subtilis subsp. subtilis str. 168 cold shock protein CspD NP_390076.1 2307905 D 224308 CDS NP_390077.1 16079253 939076 complement(2308157..2308339) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16625836; Product type f: factor; regulatory protein DegR 2308339 degR 939076 degR Bacillus subtilis subsp. subtilis str. 168 regulatory protein DegR NP_390077.1 2308157 R 224308 CDS NP_390078.1 16079254 939078 2308495..2308764 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2308764 ypzA 939078 ypzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390078.1 2308495 D 224308 CDS NP_390079.1 16079255 939077 complement(2308792..2308974) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2308974 ypeQ 939077 ypeQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390079.1 2308792 R 224308 CDS NP_390080.2 161511070 939073 complement(2308967..2309647) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2309647 ypeP 939073 ypeP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390080.2 2308967 R 224308 CDS NP_390081.1 16079257 939075 2309730..2310419 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2310419 ypdP 939075 ypdP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390081.1 2309730 D 224308 CDS NP_390082.1 16079258 939074 2310419..2310817 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9888800; 14.7 kDa ribonuclease H-like protein 2310817 ypdQ 939074 ypdQ Bacillus subtilis subsp. subtilis str. 168 14.7 kDa ribonuclease H-like protein NP_390082.1 2310419 D 224308 CDS YP_054584.1 50812255 2914255 2310859..2310987 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10333516; Product type cp: cell process; small acid-soluble spore protein L 2310987 sspL 2914255 sspL Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein L YP_054584.1 2310859 D 224308 CDS NP_390083.1 16079259 939070 complement(2310995..2311885) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16045613, 17038322, 17905985; Product type e: enzyme; 5'-3' exonuclease 2311885 exoA 939070 exoA Bacillus subtilis subsp. subtilis str. 168 5'-3' exonuclease NP_390083.1 2310995 R 224308 CDS YP_003097753.1 255767481 8302979 complement(2311986..2312132) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2312132 ypzF 8302979 ypzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097753.1 2311986 R 224308 CDS NP_390084.1 16079260 939067 complement(2312207..2312464) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2312464 ypbS 939067 ypbS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390084.1 2312207 R 224308 CDS NP_390085.1 16079261 939071 complement(2312529..2316110) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2316110 ypbR 939071 ypbR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390085.1 2312529 R 224308 CDS NP_390086.1 16079262 939072 complement(2316446..2316952) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229, 15849754, 16850406, 7726551, 8396117; Product type pe: enzyme; hypothetical protein 2316952 ypbQ 939072 ypbQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390086.1 2316446 R 224308 CDS NP_390087.1 16079263 939069 complement(2316956..2318053) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; chalcone synthase 2318053 bcsA 939069 bcsA Bacillus subtilis subsp. subtilis str. 168 chalcone synthase NP_390087.1 2316956 R 224308 CDS NP_390088.1 16079264 939068 complement(2318127..2319443) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923093, 15549109, 15849754, 16850406; Product type t: transporter; xanthine permease 2319443 pbuX 939068 pbuX Bacillus subtilis subsp. subtilis str. 168 xanthine permease NP_390088.1 2318127 R 224308 CDS NP_390089.1 16079265 939064 complement(2319440..2320024) 1 NC_000964.3 Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 2320024 xpt 939064 xpt Bacillus subtilis subsp. subtilis str. 168 xanthine phosphoribosyltransferase NP_390089.1 2319440 R 224308 CDS NP_390090.1 16079266 939061 complement(2320355..2321860) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7765282; Product type e: enzyme; metalloprotease YpwA 2321860 ypwA 939061 ypwA Bacillus subtilis subsp. subtilis str. 168 metalloprotease YpwA NP_390090.1 2320355 R 224308 CDS NP_390091.1 16079267 939065 complement(2321972..2322964) 1 NC_000964.3 transports degraded pectin products into the bacterial cell; 2-keto-3-deoxygluconate permease 2322964 kdgT 939065 kdgT Bacillus subtilis subsp. subtilis str. 168 2-keto-3-deoxygluconate permease NP_390091.1 2321972 R 224308 CDS NP_390092.1 16079268 939066 complement(2323009..2323599) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 9846747; Product type e: enzyme; KHG/KDPG aldolase 2323599 kdgA 939066 kdgA Bacillus subtilis subsp. subtilis str. 168 KHG/KDPG aldolase NP_390092.1 2323009 R 224308 CDS NP_390093.1 16079269 939058 complement(2323601..2324575) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10368143, 15039578, 9846747; Product type e : enzyme; 2-dehydro-3-deoxygluconokinase 2324575 kdgK 939058 kdgK Bacillus subtilis subsp. subtilis str. 168 2-dehydro-3-deoxygluconokinase NP_390093.1 2323601 R 224308 CDS NP_390094.1 16079270 939063 complement(2324613..2325632) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15223311, 17322190, 9846747; Product type r: regulator; LacI family transcriptional regulator 2325632 kdgR 939063 kdgR Bacillus subtilis subsp. subtilis str. 168 LacI family transcriptional regulator NP_390094.1 2324613 R 224308 CDS NP_390095.1 16079271 939062 2325854..2326681 1 NC_000964.3 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate; 4-deoxy-l-threo-5-hexosulose-uronate ketol-isomerase 2326681 kduI 939062 kduI Bacillus subtilis subsp. subtilis str. 168 4-deoxy-l-threo-5-hexosulose-uronate ketol-isomerase NP_390095.1 2325854 D 224308 CDS NP_390096.1 16079272 939059 2326683..2327447 1 NC_000964.3 Involved in the metabolism of 2-deoxyglucose; 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase 2327447 kduD 939059 kduD Bacillus subtilis subsp. subtilis str. 168 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase NP_390096.1 2326683 D 224308 CDS NP_390097.1 16079273 939060 complement(2327488..2329413) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8385320; Product type pe : enzyme; ATP-dependent helicase YpvA 2329413 ypvA 939060 ypvA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase YpvA NP_390097.1 2327488 R 224308 CDS NP_390098.1 16079274 939055 complement(2329515..2329706) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2329706 yptA 939055 yptA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390098.1 2329515 R 224308 CDS YP_003097754.1 255767482 8303061 2329870..2330022 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2330022 ypzG 8303061 ypzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097754.1 2329870 D 224308 CDS NP_390099.1 16079275 939057 complement(2330075..2331232) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA methyltransferase YpsC 2331232 ypsC 939057 ypsC Bacillus subtilis subsp. subtilis str. 168 RNA methyltransferase YpsC NP_390099.1 2330075 R 224308 CDS NP_390100.1 16079276 939054 complement(2331779..2332075) 1 NC_000964.3 GpsB; guiding PBP1 shuttling; similar to DivIVA; cell cycle protein GpsB 2332075 ypsB 939054 ypsB Bacillus subtilis subsp. subtilis str. 168 cell cycle protein GpsB NP_390100.1 2331779 R 224308 CDS NP_390101.2 255767483 939056 complement(2332153..2332782) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2332782 ypsA 939056 ypsA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390101.2 2332153 R 224308 CDS NP_390102.1 16079278 939051 complement(2332784..2333011) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10075739, 10400595, 1518043, 1691789, 2821284; Product type cp: cell process; spore coat protein D 2333011 cotD 939051 cotD Bacillus subtilis subsp. subtilis str. 168 spore coat protein D NP_390102.1 2332784 R 224308 CDS NP_390103.1 16079279 939050 complement(2333324..2334565) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2334565 yprB 939050 yprB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390103.1 2333324 R 224308 CDS NP_390104.1 16079280 939052 complement(2334581..2336830) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YprA 2336830 yprA 939052 yprA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase YprA NP_390104.1 2334581 R 224308 CDS NP_390105.1 16079281 939046 complement(2336933..2337439) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10627040; Product type pe : enzyme; PTS system transporter subunit IIA YpqE 2337439 ypqE 939046 ypqE Bacillus subtilis subsp. subtilis str. 168 PTS system transporter subunit IIA YpqE NP_390105.1 2336933 R 224308 CDS NP_390106.1 16079282 939048 2337577..2337996 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2337996 ypqA 939048 ypqA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390106.1 2337577 D 224308 CDS NP_390107.1 16079283 939049 complement(2338017..2338394) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2338394 yppG 939049 yppG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390107.1 2338017 R 224308 CDS NP_390108.1 16079284 939045 2338582..2338770 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 2338770 yppF 939045 yppF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390108.1 2338582 D 224308 CDS NP_390109.1 16079285 939047 complement(2338809..2339180) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2339180 yppE 939047 yppE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390109.1 2338809 R 224308 CDS NP_390110.1 16079286 939042 complement(2339226..2339471) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15687200; hypothetical protein 2339471 yppD 939042 yppD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390110.1 2339226 R 224308 CDS YP_054585.1 50812256 2914288 2339670..2339774 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362; Product type cp: cell process; small acid-soluble spore protein M 2339774 sspM 2914288 sspM Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein M YP_054585.1 2339670 D 224308 CDS NP_390111.1 16079287 939043 complement(2339799..2340761) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2340761 yppC 939043 yppC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390111.1 2339799 R 224308 CDS NP_390112.1 16079288 939039 2340802..2341422 1 NC_000964.3 functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; holliday junction resolvase RecU 2341422 recU 939039 recU Bacillus subtilis subsp. subtilis str. 168 holliday junction resolvase RecU NP_390112.1 2340802 D 224308 CDS NP_390113.1 16079289 939044 2341444..2344188 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10322023, 10692371, 12562814, 15262952; Product type e: enzyme; penicillin-binding protein 1A/1B 2344188 ponA 939044 ponA Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 1A/1B NP_390113.1 2341444 D 224308 CDS NP_390114.1 16079290 939041 complement(2344264..2344758) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2344758 ypoC 939041 ypoC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390114.1 2344264 R 224308 CDS NP_390115.1 16079291 939036 complement(2344755..2345414) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11160880, 12682299, 9808040; Product type e : enzyme; endonuclease III 2345414 nth 939036 nth Bacillus subtilis subsp. subtilis str. 168 endonuclease III NP_390115.1 2344755 R 224308 CDS NP_390116.1 16079292 939040 complement(2345433..2346131) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15556628, 15686560, 16002087, 16677303, 16855238, 17277452, 18206906; Product type f : factor; DNA replication protein DnaD 2346131 dnaD 939040 dnaD Bacillus subtilis subsp. subtilis str. 168 DNA replication protein DnaD NP_390116.1 2345433 R 224308 CDS NP_390117.1 16079293 939038 complement(2346224..2347516) 1 NC_000964.3 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparagine--tRNA ligase 2347516 asnC 939038 asnC Bacillus subtilis subsp. subtilis str. 168 asparagine--tRNA ligase NP_390117.1 2346224 R 224308 CDS NP_390118.1 16079294 939037 complement(2347660..2348841) 1 NC_000964.3 catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase 2348841 aspB 939037 aspB Bacillus subtilis subsp. subtilis str. 168 aspartate aminotransferase NP_390118.1 2347660 R 224308 CDS NP_390119.1 16079295 939035 complement(2348864..2349349) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2349349 ypmB 939035 ypmB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390119.1 2348864 R 224308 CDS NP_390120.1 16079296 939034 complement(2349358..2349528) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2349528 ypmA 939034 ypmA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390120.1 2349358 R 224308 CDS NP_390121.1 16079297 939031 complement(2349671..2352466) 1 NC_000964.3 unwinds DNA; ATP-dependent helicase DinG homolog 2352466 dinG 939031 dinG Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase DinG homolog NP_390121.1 2349671 R 224308 CDS NP_390122.1 16079298 939033 complement(2352592..2352975) 1 NC_000964.3 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5); aspartate 1-decarboxylase 2352975 panD 939033 panD Bacillus subtilis subsp. subtilis str. 168 aspartate 1-decarboxylase NP_390122.1 2352592 R 224308 CDS NP_390123.1 16079299 939030 complement(2352977..2353837) 1 NC_000964.3 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine; pantothenate synthetase 2353837 panC 939030 panC Bacillus subtilis subsp. subtilis str. 168 pantothenate synthetase NP_390123.1 2352977 R 224308 CDS NP_390124.1 16079300 939032 complement(2353839..2354672) 1 NC_000964.3 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 2354672 panB 939032 panB Bacillus subtilis subsp. subtilis str. 168 3-methyl-2-oxobutanoate hydroxymethyltransferase NP_390124.1 2353839 R 224308 CDS NP_390125.1 16079301 939028 complement(2354918..2355895) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12368242, 15459338; Product type e: enzyme; bifunctional protein BirA 2355895 birA 939028 birA Bacillus subtilis subsp. subtilis str. 168 bifunctional protein BirA NP_390125.1 2354918 R 224308 CDS NP_390126.1 16079302 939025 complement(2355880..2357073) 1 NC_000964.3 catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; CCA-adding enzyme 2357073 cca 939025 cca Bacillus subtilis subsp. subtilis str. 168 CCA-adding enzyme NP_390126.1 2355880 R 224308 CDS NP_390127.1 16079303 939029 complement(2357078..2358211) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751541; Product type pe : enzyme; glycosyltransferase YpjH 2358211 ypjH 939029 ypjH Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YpjH NP_390127.1 2357078 R 224308 CDS NP_390128.2 255767484 939026 complement(2358208..2358918) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11004195; deacetylase YpjG 2358918 ypjG 939026 ypjG Bacillus subtilis subsp. subtilis str. 168 deacetylase YpjG NP_390128.2 2358208 R 224308 CDS NP_390129.1 16079305 939027 complement(2358911..2359324) 1 NC_000964.3 catalyzes the formation of methylglyoxal from glycerone phosphate; methylglyoxal synthase 2359324 mgsA 939027 mgsA Bacillus subtilis subsp. subtilis str. 168 methylglyoxal synthase NP_390129.1 2358911 R 224308 CDS NP_390130.1 16079306 939024 complement(2359340..2360143) 1 NC_000964.3 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; 4-hydroxy-tetrahydrodipicolinate reductase 2360143 dapB 939024 dapB Bacillus subtilis subsp. subtilis str. 168 4-hydroxy-tetrahydrodipicolinate reductase NP_390130.1 2359340 R 224308 CDS NP_390131.1 16079307 939022 complement(2360155..2360490) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16390452; Product type e: enzyme; hypothetical protein 2360490 ypjD 939022 ypjD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390131.1 2360155 R 224308 CDS NP_390132.2 255767485 939023 2360630..2361502 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2361502 ypjC 939023 ypjC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390132.2 2360630 D 224308 CDS NP_390133.1 16079309 939020 complement(2361544..2362338) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12662922; Product type m: membrane component; hypothetical protein 2362338 ypjB 939020 ypjB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390133.1 2361544 R 224308 CDS NP_390134.1 16079310 939018 complement(2362407..2362964) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2362964 ypjA 939018 ypjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390134.1 2362407 R 224308 CDS NP_390135.1 16079311 939021 complement(2363111..2363878) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme; menaquinol-cytochrome c reductase cytochrome b/c subunit 2363878 qcrC 939021 qcrC Bacillus subtilis subsp. subtilis str. 168 menaquinol-cytochrome c reductase cytochrome b/c subunit NP_390135.1 2363111 R 224308 CDS NP_390136.1 16079312 939019 complement(2363913..2364587) 1 NC_000964.3 electron transport protein; menaquinol-cytochrome c reductase cytochrome b subunit 2364587 qcrB 939019 qcrB Bacillus subtilis subsp. subtilis str. 168 menaquinol-cytochrome c reductase cytochrome b subunit NP_390136.1 2363913 R 224308 CDS NP_390137.1 16079313 939017 complement(2364589..2365092) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12446663, 12615356, 7592464, 8647852; Product type e: enzyme; menaquinol-cytochrome c reductase iron-sulfur subunit 2365092 qcrA 939017 qcrA Bacillus subtilis subsp. subtilis str. 168 menaquinol-cytochrome c reductase iron-sulfur subunit NP_390137.1 2364589 R 224308 CDS NP_390138.1 16079314 939015 complement(2365235..2365681) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2365681 ypiF 939015 ypiF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390138.1 2365235 R 224308 CDS NP_390139.1 16079315 939016 complement(2365736..2366275) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16847875; hypothetical protein 2366275 ypiB 939016 ypiB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390139.1 2365736 R 224308 CDS NP_390140.1 16079316 939012 complement(2366347..2367618) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; TPR repeat-containing protein YpiA 2367618 ypiA 939012 ypiA Bacillus subtilis subsp. subtilis str. 168 TPR repeat-containing protein YpiA NP_390140.1 2366347 R 224308 CDS NP_390141.1 16079317 939014 complement(2367954..2369240) 1 NC_000964.3 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase 2369240 aroE 939014 aroE Bacillus subtilis subsp. subtilis str. 168 3-phosphoshikimate 1-carboxyvinyltransferase NP_390141.1 2367954 R 224308 CDS NP_390142.1 16079318 939013 complement(2369251..2370366) 1 NC_000964.3 catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase 2370366 tyrA 939013 tyrA Bacillus subtilis subsp. subtilis str. 168 prephenate dehydrogenase NP_390142.1 2369251 R 224308 CDS NP_390143.2 255767486 939009 complement(2370415..2371497) 1 NC_000964.3 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; histidinol-phosphate aminotransferase 2371497 hisC 939009 hisC Bacillus subtilis subsp. subtilis str. 168 histidinol-phosphate aminotransferase NP_390143.2 2370415 R 224308 CDS NP_390144.1 16079320 939011 complement(2371508..2372311) 1 NC_000964.3 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase alpha chain 2372311 trpA 939011 trpA Bacillus subtilis subsp. subtilis str. 168 tryptophan synthase alpha chain NP_390144.1 2371508 R 224308 CDS NP_390145.2 50812257 939010 complement(2372304..2373506) 1 NC_000964.3 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase beta chain 2373506 trpB 939010 trpB Bacillus subtilis subsp. subtilis str. 168 tryptophan synthase beta chain NP_390145.2 2372304 R 224308 CDS NP_390146.3 255767487 939006 complement(2373487..2374134) 1 NC_000964.3 catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase 2374134 trpF 939006 trpF Bacillus subtilis subsp. subtilis str. 168 N-(5'-phosphoribosyl)anthranilate isomerase NP_390146.3 2373487 R 224308 CDS NP_390147.3 255767488 939004 complement(2374139..2374888) 1 NC_000964.3 involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol phosphate synthase 2374888 trpC 939004 trpC Bacillus subtilis subsp. subtilis str. 168 indole-3-glycerol phosphate synthase NP_390147.3 2374139 R 224308 CDS NP_390148.2 50812260 939007 complement(2374881..2375897) 1 NC_000964.3 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase 2375897 trpD 939007 trpD Bacillus subtilis subsp. subtilis str. 168 anthranilate phosphoribosyltransferase NP_390148.2 2374881 R 224308 CDS NP_390149.1 16079325 939008 complement(2375869..2377416) 1 NC_000964.3 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component 1 2377416 trpE 939008 trpE Bacillus subtilis subsp. subtilis str. 168 anthranilate synthase component 1 NP_390149.1 2375869 R 224308 CDS NP_390150.1 16079326 939005 complement(2377632..2378015) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10818343, 15865424, 16060652, 2105742, 8378335, 9384560; Product type e : enzyme; chorismate mutase AroH 2378015 aroH 939005 aroH Bacillus subtilis subsp. subtilis str. 168 chorismate mutase AroH NP_390150.1 2377632 R 224308 CDS NP_390151.1 16079327 939001 complement(2378012..2379100) 1 NC_000964.3 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase 2379100 aroB 939001 aroB Bacillus subtilis subsp. subtilis str. 168 3-dehydroquinate synthase NP_390151.1 2378012 R 224308 CDS NP_390152.3 255767489 939000 complement(2379100..2380272) 1 NC_000964.3 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase 2380272 aroF 939000 aroF Bacillus subtilis subsp. subtilis str. 168 chorismate synthase NP_390152.3 2379100 R 224308 CDS NP_390153.2 50812262 939003 complement(2380347..2381117) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10196193, 15544802, 7635819, 7893679, 8244966; Product type e: enzyme; chemotaxis protein methyltransferase 2381117 cheR 939003 cheR Bacillus subtilis subsp. subtilis str. 168 chemotaxis protein methyltransferase NP_390153.2 2380347 R 224308 CDS NP_390154.1 16079330 938997 complement(2381354..2381803) 1 NC_000964.3 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 2381803 ndk 938997 ndk Bacillus subtilis subsp. subtilis str. 168 nucleoside diphosphate kinase NP_390154.1 2381354 R 224308 CDS NP_390155.1 16079331 939002 complement(2381919..2382965) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme; heptaprenyl diphosphate synthase component 2 2382965 hepT 939002 hepT Bacillus subtilis subsp. subtilis str. 168 heptaprenyl diphosphate synthase component 2 NP_390155.1 2381919 R 224308 CDS NP_390156.1 16079332 938999 complement(2382907..2383608) 1 NC_000964.3 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone; demethylmenaquinone methyltransferase 2383608 ubiE 938999 ubiE Bacillus subtilis subsp. subtilis str. 168 demethylmenaquinone methyltransferase NP_390156.1 2382907 R 224308 CDS NP_390157.1 16079333 938998 complement(2383615..2384370) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10545188, 9139683, 9720033, 9756625; Product type e: enzyme; heptaprenyl diphosphate synthase component 1 2384370 hepS 938998 hepS Bacillus subtilis subsp. subtilis str. 168 heptaprenyl diphosphate synthase component 1 NP_390157.1 2383615 R 224308 CDS NP_390158.1 16079334 938996 complement(2384534..2384761) 1 NC_000964.3 tryptophan RNA-binding attenuator protein; binds leader Trp transcript causing transcription termination; transcription attenuation protein MtrB 2384761 mtrB 938996 mtrB Bacillus subtilis subsp. subtilis str. 168 transcription attenuation protein MtrB NP_390158.1 2384534 R 224308 CDS NP_390159.1 16079335 938994 complement(2384783..2385355) 1 NC_000964.3 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase 1 2385355 folE 938994 folE Bacillus subtilis subsp. subtilis str. 168 GTP cyclohydrolase 1 NP_390159.1 2384783 R 224308 CDS NP_390160.1 16079336 938995 complement(2385543..2385821) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10224127, 10231583, 10715001, 11931565, 1382620, 9106208; Product type f : factor; DNA-binding protein HU 1 2385821 hbs 938995 hbs Bacillus subtilis subsp. subtilis str. 168 DNA-binding protein HU 1 NP_390160.1 2385543 R 224308 CDS NP_390161.1 16079337 938991 complement(2386195..2387673) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160095, 17114257, 17427285; Product type cp: cell process; stage IV sporulation protein A 2387673 spoIVA 938991 spoIVA Bacillus subtilis subsp. subtilis str. 168 stage IV sporulation protein A NP_390161.1 2386195 R 224308 CDS NP_390162.1 16079338 938992 complement(2387854..2388588) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 2388588 yphF 938992 yphF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390162.1 2387854 R 224308 CDS NP_390163.1 16079339 938993 complement(2388610..2388813) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2388813 yphE 938993 yphE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390163.1 2388610 R 224308 CDS NP_390164.1 16079340 938989 complement(2389151..2390188) 1 NC_000964.3 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; glycerol-3-phosphate dehydrogenase 2390188 gpsA 938989 gpsA Bacillus subtilis subsp. subtilis str. 168 glycerol-3-phosphate dehydrogenase NP_390164.1 2389151 R 224308 CDS NP_390165.1 16079341 938988 complement(2390206..2391516) 1 NC_000964.3 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTPase Der 2391516 engA 938988 engA Bacillus subtilis subsp. subtilis str. 168 GTPase Der NP_390165.1 2390206 R 224308 CDS YP_003097755.1 255767490 8303000 complement(2391670..2391864) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2391864 ypzH 8303000 ypzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097755.1 2391670 R 224308 CDS NP_390166.1 16079342 938990 complement(2391861..2392754) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2392754 seaA 938990 seaA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390166.1 2391861 R 224308 CDS NP_390167.1 16079343 938987 complement(2392751..2393350) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2393350 yphA 938987 yphA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390167.1 2392751 R 224308 CDS YP_003097756.1 255767491 8303059 2393422..2393559 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2393559 ypzI 8303059 ypzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097756.1 2393422 D 224308 CDS NP_390168.3 255767492 938985 complement(2393602..2394651) 1 NC_000964.3 catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl-diphosphate delta-isomerase 2394651 fni 938985 fni Bacillus subtilis subsp. subtilis str. 168 isopentenyl-diphosphate delta-isomerase NP_390168.3 2393602 R 224308 CDS NP_390169.1 16079345 938986 complement(2394664..2395812) 1 NC_000964.3 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 homolog 2395812 rpsA 938986 rpsA Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S1 homolog NP_390169.1 2394664 R 224308 CDS NP_390170.1 16079346 938982 complement(2396045..2396719) 1 NC_000964.3 Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase 2396719 cmk 938982 cmk Bacillus subtilis subsp. subtilis str. 168 cytidylate kinase NP_390170.1 2396045 R 224308 CDS NP_390171.1 16079347 938983 complement(2396798..2396974) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2396974 ypfB 938983 ypfB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390171.1 2396798 R 224308 CDS NP_390172.1 16079348 938984 complement(2397019..2397672) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16249258; Product type pr : regulator; c-di-GMP receptor protein 2397672 dgrA 938984 dgrA Bacillus subtilis subsp. subtilis str. 168 c-di-GMP receptor protein NP_390172.1 2397019 R 224308 CDS NP_390173.1 16079349 938981 complement(2397765..2399117) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332; Product type cp: cell process; sporulation protein YpeB 2399117 ypeB 938981 ypeB Bacillus subtilis subsp. subtilis str. 168 sporulation protein YpeB NP_390173.1 2397765 R 224308 CDS NP_390174.1 16079350 938979 complement(2399152..2400069) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658652, 12177332, 16905870, 16907803; Product type cp: cell process; spore cortex-lytic enzyme 2400069 sleB 938979 sleB Bacillus subtilis subsp. subtilis str. 168 spore cortex-lytic enzyme NP_390174.1 2399152 R 224308 CDS NP_390175.1 16079351 938978 complement(2400208..2400864) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16816000, 16850406, 17020587; Product type e: enzyme; protease PrsW 2400864 prsW 938978 prsW Bacillus subtilis subsp. subtilis str. 168 protease PrsW NP_390175.1 2400208 R 224308 CDS NP_390176.2 255767493 938977 complement(2400984..2401958) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2401958 ypdA 938977 ypdA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390176.2 2400984 R 224308 CDS NP_390177.2 255767494 938975 complement(2402067..2403350) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18326565, 9829940; Product type e: enzyme; cryptic catabolic NAD-specific glutamate dehydrogenase GudB 2403350 gudB 938975 gudB Bacillus subtilis subsp. subtilis str. 168 cryptic catabolic NAD-specific glutamate dehydrogenase GudB NP_390177.2 2402067 R 224308 CDS NP_390178.1 16079354 938980 complement(2403506..2404090) 1 NC_000964.3 enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adapter protein MecA 2 2404090 ypbH 938980 ypbH Bacillus subtilis subsp. subtilis str. 168 adapter protein MecA 2 NP_390178.1 2403506 R 224308 CDS NP_390179.1 16079355 938974 complement(2404249..2405028) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme; hypothetical protein 2405028 ypbG 938974 ypbG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390179.1 2404249 R 224308 CDS NP_390180.1 16079356 938976 complement(2405114..2405557) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2405557 ypbF 938976 ypbF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390180.1 2405114 R 224308 CDS NP_390181.1 16079357 938971 complement(2405620..2406342) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855244; hypothetical protein 2406342 ypbE 938971 ypbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390181.1 2405620 R 224308 CDS NP_390182.1 16079358 938972 complement(2406293..2406862) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; hypothetical protein 2406862 ypbD 938972 ypbD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390182.1 2406293 R 224308 CDS NP_390183.1 16079359 938969 complement(2406922..2408412) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16385024; Product type e: enzyme; ATP-dependent DNA helicase RecS 2408412 recQ 938969 recQ Bacillus subtilis subsp. subtilis str. 168 ATP-dependent DNA helicase RecS NP_390183.1 2406922 R 224308 CDS NP_390184.1 16079360 938973 complement(2408405..2409463) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2409463 ypbB 938973 ypbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390184.1 2408405 R 224308 CDS NP_390185.1 16079361 938968 2409729..2409977 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12538057; Product type c: carrier; ferredoxin 2409977 fer 938968 fer Bacillus subtilis subsp. subtilis str. 168 ferredoxin NP_390185.1 2409729 D 224308 CDS NP_390186.1 16079362 938970 complement(2410017..2410589) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 15849754, 16850406, 17693491; Product type t: transporter; riboflavin transporter FmnP 2410589 fmnP 938970 fmnP Bacillus subtilis subsp. subtilis str. 168 riboflavin transporter FmnP NP_390186.1 2410017 R 224308 CDS NP_390187.1 16079363 938967 complement(2410695..2410859) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2410859 ypzE 938967 ypzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390187.1 2410695 R 224308 CDS NP_390188.2 255767495 938964 2411086..2412663 1 NC_000964.3 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; D-3-phosphoglycerate dehydrogenase 2412663 serA 938964 serA Bacillus subtilis subsp. subtilis str. 168 D-3-phosphoglycerate dehydrogenase NP_390188.2 2411086 D 224308 CDS NP_390189.1 16079365 938963 complement(2412706..2413473) 1 NC_000964.3 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase 2413473 aroD 938963 aroD Bacillus subtilis subsp. subtilis str. 168 3-dehydroquinate dehydratase NP_390189.1 2412706 R 224308 CDS NP_390190.2 255767496 938959 complement(2413585..2414691) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10712692, 14762009, 9393439; Product type r: regulator; sigma-X negative effector 2414691 rsiX 938959 rsiX Bacillus subtilis subsp. subtilis str. 168 sigma-X negative effector NP_390190.2 2413585 R 224308 CDS NP_390191.2 255767497 938966 complement(2414627..2415211) 1 NC_000964.3 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; in B. subtilis has been shown to regulate cell envelope modification and may effect antibiotic resistance; RNA polymerase sigma factor SigX 2415211 sigX 938966 sigX Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigX NP_390191.2 2414627 R 224308 CDS NP_390192.1 16079368 938965 complement(2415415..2417184) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11222591, 14996800, 16825793, 16885456, 17189364, 17322317; Product type rc : receptor; sensor histidine kinase 2417184 resE 938965 resE Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_390192.1 2415415 R 224308 CDS NP_390193.2 255767498 938960 complement(2417181..2417903) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972836, 15028686, 15375128, 16825793, 16885456, 17322317; Product type r : regulator; transcriptional regulatory protein ResD 2417903 resD 938960 resD Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein ResD NP_390193.2 2417181 R 224308 CDS NP_390194.2 255767499 938962 complement(2417984..2419159) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 15849754, 16850406; Product type f: factor; cytochrome c biogenesis protein ResC 2419159 resC 938962 resC Bacillus subtilis subsp. subtilis str. 168 cytochrome c biogenesis protein ResC NP_390194.2 2417984 R 224308 CDS NP_390195.1 16079371 938961 complement(2419179..2420807) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10844653, 12682299, 16825793, 9395519; Product type f: factor; cytochrome c biogenesis protein ResB 2420807 resB 938961 resB Bacillus subtilis subsp. subtilis str. 168 cytochrome c biogenesis protein ResB NP_390195.1 2419179 R 224308 CDS NP_390196.2 255767500 938958 complement(2420804..2421343) 1 NC_000964.3 catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c; thiol-disulfide oxidoreductase ResA 2421343 resA 938958 resA Bacillus subtilis subsp. subtilis str. 168 thiol-disulfide oxidoreductase ResA NP_390196.2 2420804 R 224308 CDS NP_390197.2 255767501 938955 complement(2421438..2422172) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9888802; Product type e : enzyme; ribosomal large subunit pseudouridine synthase B 2422172 rluB 938955 rluB Bacillus subtilis subsp. subtilis str. 168 ribosomal large subunit pseudouridine synthase B NP_390197.2 2421438 R 224308 CDS NP_390198.2 255767502 938957 complement(2422264..2422800) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process; spore maturation protein B 2422800 spmB 938957 spmB Bacillus subtilis subsp. subtilis str. 168 spore maturation protein B NP_390198.2 2422264 R 224308 CDS NP_390199.1 16079375 938954 complement(2422805..2423395) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7642500; Product type cp: cell process; spore maturation protein A 2423395 spmA 938954 spmA Bacillus subtilis subsp. subtilis str. 168 spore maturation protein A NP_390199.1 2422805 R 224308 CDS NP_390200.1 16079376 938953 complement(2423383..2424531) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498740, 7642500, 8892816, 9864321; Product type cp: cell process; D-alanyl-D-alanine carboxypeptidase DacB 2424531 dacB 938953 dacB Bacillus subtilis subsp. subtilis str. 168 D-alanyl-D-alanine carboxypeptidase DacB NP_390200.1 2423383 R 224308 CDS NP_390201.1 16079377 938956 complement(2424654..2425193) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12065423; hypothetical protein 2425193 ypuI 938956 ypuI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390201.1 2424654 R 224308 CDS NP_390202.1 16079378 938951 complement(2425248..2425841) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12100548, 12682299, 12897137; Product type f: factor; segregation and condensation protein B 2425841 spcB 938951 spcB Bacillus subtilis subsp. subtilis str. 168 segregation and condensation protein B NP_390202.1 2425248 R 224308 CDS NP_390203.1 16079379 938950 complement(2425831..2426586) 1 NC_000964.3 functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A 2426586 scpA 938950 scpA Bacillus subtilis subsp. subtilis str. 168 segregation and condensation protein A NP_390203.1 2425831 R 224308 CDS NP_390204.1 16079380 938952 2426867..2427391 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2427391 ypuF 938952 ypuF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390204.1 2426867 D 224308 CDS NP_390205.1 16079381 938948 complement(2427405..2427779) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15466513; Product type pe : enzyme; riboflavin biosynthesis protein RibT 2427779 ypzK 938948 ypzK Bacillus subtilis subsp. subtilis str. 168 riboflavin biosynthesis protein RibT NP_390205.1 2427405 R 224308 CDS NP_390206.1 16079382 938949 complement(2427892..2428356) 1 NC_000964.3 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 2428356 ribH 938949 ribH Bacillus subtilis subsp. subtilis str. 168 6,7-dimethyl-8-ribityllumazine synthase NP_390206.1 2427892 R 224308 CDS NP_390207.1 16079383 938946 complement(2428389..2429585) 1 NC_000964.3 bifunctional enzyme DHBP synthase/GTP cyclohydrolase II; functions in riboflavin synthesis; converts GTP to 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine; converts ribulose 5-phopshate to 3,4-dihydroxy-2-butanone 4-phosphate; riboflavin biosynthesis protein RibBA 2429585 ribA 938946 ribA Bacillus subtilis subsp. subtilis str. 168 riboflavin biosynthesis protein RibBA NP_390207.1 2428389 R 224308 CDS NP_390208.1 16079384 938947 complement(2429600..2430247) 1 NC_000964.3 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase 2430247 ribE 938947 ribE Bacillus subtilis subsp. subtilis str. 168 riboflavin synthase NP_390208.1 2429600 R 224308 CDS NP_390209.1 16079385 938945 complement(2430258..2431343) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12456892, 18986985, 9068650; Product type e: enzyme; riboflavin biosynthesis protein RibD 2431343 ribD 938945 ribD Bacillus subtilis subsp. subtilis str. 168 riboflavin biosynthesis protein RibD NP_390209.1 2430258 R 224308 CDS NP_390211.1 16079387 938943 complement(2431737..2432081) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2432081 ypuD 938943 ypuD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390211.1 2431737 R 224308 CDS NP_390212.1 16079388 938944 complement(2432316..2432870) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15502345, 11004175, 10982814, 9694797, 9823656, 10198007, 10336490; Product type e: enzyme; signal peptidase I S 2432870 sipS 938944 sipS Bacillus subtilis subsp. subtilis str. 168 signal peptidase I S NP_390212.1 2432316 R 224308 CDS NP_390213.1 16079389 938940 2433137..2433373 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2433373 ypzC 938940 ypzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390213.1 2433137 D 224308 CDS YP_003097757.1 255767503 8302956 complement(2433316..2433522) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2433522 ypzJ 8302956 ypzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097757.1 2433316 R 224308 CDS NP_390215.1 16079391 938942 complement(2434143..2434346) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2434346 ypuB 938942 ypuB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390215.1 2434143 R 224308 CDS NP_390216.1 16079392 938937 2435012..2435224 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; spore germination protein-like protein YpzD 2435224 ypzD 938937 ypzD Bacillus subtilis subsp. subtilis str. 168 spore germination protein-like protein YpzD NP_390216.1 2435012 D 224308 CDS NP_390217.1 16079393 938934 complement(2435360..2435791) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8639516, 9063446, 9748346; Product type e: enzyme; peptidyl-prolyl cis-trans isomerase 2435791 ppiB 938934 ppiB Bacillus subtilis subsp. subtilis str. 168 peptidyl-prolyl cis-trans isomerase NP_390217.1 2435360 R 224308 CDS NP_390218.1 16079394 938939 2436045..2436917 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17434969; Product type pf : factor; hypothetical protein 2436917 ypuA 938939 ypuA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390218.1 2436045 D 224308 CDS NP_390219.1 16079395 938931 complement(2436947..2438266) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14627808, 9044297; Product type e: enzyme; diaminopimelate decarboxylase 2438266 lysA 938931 lysA Bacillus subtilis subsp. subtilis str. 168 diaminopimelate decarboxylase NP_390219.1 2436947 R 224308 CDS NP_390220.2 255767504 938936 complement(2438372..2439853) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process; stage V sporulation protein AF 2439853 spoVAF 938936 spoVAF Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AF NP_390220.2 2438372 R 224308 CDS YP_003097758.1 255767505 8303022 complement(2439804..2440415) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113, 17573930; Product type cp: cell process; stage V sporulation protein AE 2440415 spoVAEA 8303022 spoVAEA Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AE YP_003097758.1 2439804 R 224308 CDS YP_003097759.1 255767506 8303020 complement(2440423..2440773) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17573930; Product type cp: cell process; stage V sporulation protein AEB 2440773 spoVAEB 8303020 spoVAEB Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AEB YP_003097759.1 2440423 R 224308 CDS NP_390222.1 16079398 938932 complement(2440775..2441791) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16077113; Product type cp: cell process; stage V sporulation protein AD 2441791 spoVAD 938932 spoVAD Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AD NP_390222.1 2440775 R 224308 CDS NP_390223.1 16079399 938733 complement(2441804..2442256) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process; stage V sporulation protein AC 2442256 spoVAC 938733 spoVAC Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AC NP_390223.1 2441804 R 224308 CDS NP_390224.1 16079400 938933 complement(2442269..2442694) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16077113, 16850406; Product type cp: cell process; stage V sporulation protein AB 2442694 spoVAB 938933 spoVAB Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AB NP_390224.1 2442269 R 224308 CDS NP_390225.2 255767507 938734 complement(2442684..2443304) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 3114420; Product type cp: cell process; stage V sporulation protein AA 2443304 spoVAA 938734 spoVAA Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein AA NP_390225.2 2442684 R 224308 CDS NP_390226.1 16079402 938729 complement(2443429..2444196) 1 NC_000964.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor is responsible for the expression of sporulation specific genes and is expressed in the prespore at the onset of sporulation. Interaction with spoIIAB inhibits sigma F activity throughout the cell before the formation of the asymmetric septum; after septation the interaction is confined to the mother cell, and sigma F activity is released in the prespore.; RNA polymerase sigma-F factor 2444196 sigF 938729 sigF Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-F factor NP_390226.1 2443429 R 224308 CDS NP_390227.1 16079403 938930 complement(2444208..2444648) 1 NC_000964.3 binds to sigma F preventing its association with RNA polymerase during sporulation; anti-sigma F factor 2444648 spoIIAB 938930 spoIIAB Bacillus subtilis subsp. subtilis str. 168 anti-sigma F factor NP_390227.1 2444208 R 224308 CDS NP_390228.1 16079404 938730 complement(2444645..2444998) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11173484, 15819616, 16824103; Product type cp: cell process; anti-sigma F factor antagonist 2444998 spoIIAA 938730 spoIIAA Bacillus subtilis subsp. subtilis str. 168 anti-sigma F factor antagonist NP_390228.1 2444645 R 224308 CDS NP_390229.1 16079405 938732 complement(2445094..2446263) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8021191, 8936302, 9864321; Product type cp: cell process; D-alanyl-D-alanine carboxypeptidase DacF 2446263 dacF 938732 dacF Bacillus subtilis subsp. subtilis str. 168 D-alanyl-D-alanine carboxypeptidase DacF NP_390229.1 2445094 R 224308 CDS NP_390230.1 16079406 938731 complement(2446418..2447233) 1 NC_000964.3 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 1 2447233 pupG 938731 pupG Bacillus subtilis subsp. subtilis str. 168 purine nucleoside phosphorylase 1 NP_390230.1 2446418 R 224308 CDS NP_390231.2 255767508 938728 complement(2447246..2448430) 1 NC_000964.3 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 2448430 drm 938728 drm Bacillus subtilis subsp. subtilis str. 168 phosphopentomutase NP_390231.2 2447246 R 224308 CDS NP_390232.2 255767509 938726 complement(2448591..2449481) 1 NC_000964.3 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; tyrosine recombinase XerD 2449481 xerD 938726 xerD Bacillus subtilis subsp. subtilis str. 168 tyrosine recombinase XerD NP_390232.2 2448591 R 224308 CDS YP_003097760.1 255767510 8302907 complement(2449489..2449716) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2449716 yqzK 8302907 yqzK Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097760.1 2449489 R 224308 CDS NP_390233.2 255767511 938727 complement(2449841..2450290) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 12374814, 14563870, 15802251, 16672620; Product type r: regulator; ferric uptake regulation protein 2450290 fur 938727 fur Bacillus subtilis subsp. subtilis str. 168 ferric uptake regulation protein NP_390233.2 2449841 R 224308 CDS NP_390234.1 16079410 938723 complement(2450403..2451047) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17376078; Product type cp: cell process; stage II sporulation protein M 2451047 spoIIM 938723 spoIIM Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein M NP_390234.1 2450403 R 224308 CDS NP_390235.1 16079411 938724 complement(2451148..2451363) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2451363 yqkK 938724 yqkK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390235.1 2451148 R 224308 CDS NP_390236.1 16079412 938725 complement(2451463..2452782) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme; NAD-dependent malic enzyme 1 2452782 mleA 938725 mleA Bacillus subtilis subsp. subtilis str. 168 NAD-dependent malic enzyme 1 NP_390236.1 2451463 R 224308 CDS NP_390237.1 16079413 938720 complement(2452800..2454206) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10903309, 15849754, 16850406; Product type t: transporter; malate-2H(+)/Na(+)-lactate antiporter 2454206 mleN 938720 mleN Bacillus subtilis subsp. subtilis str. 168 malate-2H(+)/Na(+)-lactate antiporter NP_390237.1 2452800 R 224308 CDS NP_390238.2 255767512 938721 complement(2454347..2455774) 1 NC_000964.3 catalyzes the formation of fumarate from aspartate; aspartate ammonia-lyase 2455774 aspA 938721 aspA Bacillus subtilis subsp. subtilis str. 168 aspartate ammonia-lyase NP_390238.2 2454347 R 224308 CDS NP_390239.1 16079415 938722 complement(2455819..2456808) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346, 1711029; Product type e: enzyme; L-asparaginase 1 2456808 ansA 938722 ansA Bacillus subtilis subsp. subtilis str. 168 L-asparaginase 1 NP_390239.1 2455819 R 224308 CDS NP_390240.1 16079416 938717 2456990..2457340 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11914346; Product type r: regulator; XRE family transcriptional regulator 2457340 ansR 938717 ansR Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_390240.1 2456990 D 224308 CDS NP_390241.2 255767513 938718 complement(2457349..2458512) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2458512 yqxK 938718 yqxK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390241.2 2457349 R 224308 CDS NP_390242.1 16079418 938719 complement(2458509..2459066) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10542272, 17693564; Product type e: enzyme; adp-ribose pyrophosphatase 2459066 nudF 938719 nudF Bacillus subtilis subsp. subtilis str. 168 adp-ribose pyrophosphatase NP_390242.1 2458509 R 224308 CDS NP_390243.1 16079419 938714 2459326..2460246 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15317791, 16242712, 9643546; Product type e: enzyme; oxidoreductase 2460246 yqkF 938714 yqkF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390243.1 2459326 D 224308 CDS NP_390244.1 16079420 938715 complement(2460278..2460502) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2460502 yqkE 938715 yqkE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390244.1 2460278 R 224308 CDS NP_390245.1 16079421 938716 2460664..2461581 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2461581 yqkD 938716 yqkD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390245.1 2460664 D 224308 CDS NP_390246.1 16079422 938711 complement(2461621..2461860) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2461860 yqkC 938711 yqkC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390246.1 2461621 R 224308 CDS NP_390247.1 16079423 938713 complement(2461873..2462196) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2462196 yqkB 938713 yqkB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390247.1 2461873 R 224308 CDS NP_390248.1 16079424 938712 complement(2462193..2463224) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2463224 yqkA 938712 yqkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390248.1 2462193 R 224308 CDS NP_390249.1 16079425 938708 complement(2463217..2463561) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 2463561 yqjZ 938708 yqjZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390249.1 2463217 R 224308 CDS NP_390250.1 16079426 938709 complement(2463571..2464041) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16267290; Product type pe : enzyme; hypothetical protein 2464041 yqjY 938709 yqjY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390250.1 2463571 R 224308 CDS NP_390251.1 16079427 938710 complement(2464227..2464565) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12137951, 16267290; hypothetical protein 2464565 yqjX 938710 yqjX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390251.1 2464227 R 224308 CDS NP_390252.1 16079428 938705 complement(2464562..2465800) 1 NC_000964.3 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 2 2465800 yqjW 938705 yqjW Bacillus subtilis subsp. subtilis str. 168 DNA polymerase IV 2 NP_390252.1 2464562 R 224308 CDS NP_390253.1 16079429 938707 2465966..2466172 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2466172 yqzH 938707 yqzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390253.1 2465966 D 224308 CDS NP_390254.2 255767514 938706 2466721..2467953 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527, 15849754, 16850406; Product type pt: transporter; MFS transporter 2467953 yqjV 938706 yqjV Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_390254.2 2466721 D 224308 CDS NP_390255.1 16079431 938702 2467971..2468162 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2468162 yqjU 938702 yqjU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390255.1 2467971 D 224308 CDS NP_390256.1 16079432 938703 complement(2468159..2468545) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2468545 yqjT 938703 yqjT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390256.1 2468159 R 224308 CDS NP_390257.2 50812263 938704 complement(2468549..2469508) 1 NC_000964.3 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase 2469508 coaA 938704 coaA Bacillus subtilis subsp. subtilis str. 168 pantothenate kinase NP_390257.2 2468549 R 224308 CDS NP_390258.2 255767515 938700 complement(2469580..2470926) 1 NC_000964.3 catalyzes the formation of pyruvate from serine; D-serine dehydratase 2470926 dsdA 938700 dsdA Bacillus subtilis subsp. subtilis str. 168 D-serine dehydratase NP_390258.2 2469580 R 224308 CDS NP_390259.1 16079435 938699 complement(2471002..2471781) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2471781 yqjQ 938699 yqjQ Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390259.1 2471002 R 224308 CDS NP_390260.1 16079436 938701 complement(2471787..2472746) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2472746 yqjP 938701 yqjP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390260.1 2471787 R 224308 CDS NP_390261.1 16079437 938697 2473151..2473987 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418582; Product type e: enzyme; pyrroline-5-carboxylate reductase 2 2473987 proI 938697 proI Bacillus subtilis subsp. subtilis str. 168 pyrroline-5-carboxylate reductase 2 NP_390261.1 2473151 D 224308 CDS NP_390262.2 255767516 938696 complement(2474028..2475671) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2475671 yqjN 938696 yqjN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390262.2 2474028 R 224308 CDS NP_390263.1 16079439 938698 2475843..2476859 1 NC_000964.3 catalyzes the reduction of alpha, beta-unsaturated aldehydes and ketones; reduces the nitro group nitroester and nitroaromatic compounds; NADPH dehydrogenase 2476859 yqjM 938698 yqjM Bacillus subtilis subsp. subtilis str. 168 NADPH dehydrogenase NP_390263.1 2475843 D 224308 CDS NP_390264.1 16079440 938693 2476969..2477730 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15838020; Product type pe : enzyme; hypothetical protein 2477730 yqjL 938693 yqjL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390264.1 2476969 D 224308 CDS NP_390265.1 16079441 938694 complement(2478006..2478929) 1 NC_000964.3 member of metallo-beta-lactamase; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 2478929 yqjK 938694 yqjK Bacillus subtilis subsp. subtilis str. 168 ribonuclease Z NP_390265.1 2478006 R 224308 CDS NP_390266.2 255767517 938690 2479156..2480625 1 NC_000964.3 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase 2480625 zwf 938690 zwf Bacillus subtilis subsp. subtilis str. 168 glucose-6-phosphate 1-dehydrogenase NP_390266.2 2479156 D 224308 CDS NP_390267.2 50812264 938695 complement(2480750..2482159) 1 NC_000964.3 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 2482159 yqjI 938695 yqjI Bacillus subtilis subsp. subtilis str. 168 6-phosphogluconate dehydrogenase NP_390267.2 2480750 R 224308 CDS NP_390268.2 255767518 938691 complement(2482269..2483513) 1 NC_000964.3 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV 1 2483513 yqjH 938691 yqjH Bacillus subtilis subsp. subtilis str. 168 DNA polymerase IV 1 NP_390268.2 2482269 R 224308 CDS YP_054586.1 50812265 2914225 2483586..2483873 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2483873 yqzJ 2914225 yqzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054586.1 2483586 D 224308 CDS NP_390269.1 16079445 938692 2483904..2484731 1 NC_000964.3 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; membrane protein insertase MisCB 2484731 yqjG 938692 yqjG Bacillus subtilis subsp. subtilis str. 168 membrane protein insertase MisCB NP_390269.1 2483904 D 224308 CDS NP_390270.3 255767519 938688 2484911..2485639 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2485639 yqjF 938688 yqjF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390270.3 2484911 D 224308 CDS NP_390271.2 255767520 938687 complement(2485680..2486795) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2486795 yqjE 938687 yqjE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390271.2 2485680 R 224308 CDS NP_390272.2 255767521 938685 complement(2486813..2488336) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; propionyl-CoA carboxylase beta chain 2488336 yqjD 938685 yqjD Bacillus subtilis subsp. subtilis str. 168 propionyl-CoA carboxylase beta chain NP_390272.2 2486813 R 224308 CDS NP_390273.2 255767522 938689 complement(2488329..2488751) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2488751 yqjC 938689 yqjC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390273.2 2488329 R 224308 CDS NP_390274.1 16079450 938684 complement(2488953..2489483) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; L,D-transpeptidase YqjB 2489483 yqjB 938684 yqjB Bacillus subtilis subsp. subtilis str. 168 L,D-transpeptidase YqjB NP_390274.1 2488953 R 224308 CDS NP_390275.2 255767523 938681 complement(2489535..2490503) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2490503 yqjA 938681 yqjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390275.2 2489535 R 224308 CDS NP_390276.1 16079452 938686 complement(2490574..2491296) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter; arginine transport ATP-binding protein ArtM 2491296 artR 938686 artR Bacillus subtilis subsp. subtilis str. 168 arginine transport ATP-binding protein ArtM NP_390276.1 2490574 R 224308 CDS NP_390277.1 16079453 938678 complement(2491289..2491948) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15849754, 16850406; Product type t: transporter; arginine transport system permease protein ArtQ 2491948 artQ 938678 artQ Bacillus subtilis subsp. subtilis str. 168 arginine transport system permease protein ArtQ NP_390277.1 2491289 R 224308 CDS NP_390278.1 16079454 938682 complement(2492029..2492796) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008; Product type t: transporter; arginine-binding extracellular protein ArtP 2492796 artP 938682 artP Bacillus subtilis subsp. subtilis str. 168 arginine-binding extracellular protein ArtP NP_390278.1 2492029 R 224308 CDS NP_390279.1 16079455 938683 complement(2493064..2493501) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2493501 yqiW 938683 yqiW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390279.1 2493064 R 224308 CDS NP_390280.2 255767524 938679 2493662..2494555 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10220166, 7961792, 8098708; Product type pe: enzyme; lipid kinase BmrU 2494555 bmrU 938679 bmrU Bacillus subtilis subsp. subtilis str. 168 lipid kinase BmrU NP_390280.2 2493662 D 224308 CDS NP_390281.2 255767525 938680 2494656..2495825 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10961951, 11321573, 15849754, 16850406; Product type t : transporter; multidrug resistance protein 2495825 bmr 938680 bmr Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein NP_390281.2 2494656 D 224308 CDS NP_390282.2 50812267 938676 2495898..2496734 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11201751, 11839496, 12682015, 14985361; Product type r: regulator; MerR family transcriptional regulator 2496734 bmrR 938676 bmrR Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_390282.2 2495898 D 224308 CDS NP_390283.1 16079459 938677 complement(2496796..2498070) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex 2498070 bkdB 938677 bkdB Bacillus subtilis subsp. subtilis str. 168 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex NP_390283.1 2496796 R 224308 CDS NP_390284.1 16079460 938672 complement(2498093..2499076) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; 2-oxoisovalerate dehydrogenase subunit beta 2499076 bkdAB 938672 bkdAB Bacillus subtilis subsp. subtilis str. 168 2-oxoisovalerate dehydrogenase subunit beta NP_390284.1 2498093 R 224308 CDS NP_390285.1 16079461 938674 complement(2499090..2500082) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; 2-oxoisovalerate dehydrogenase subunit alpha 2500082 bkdAA 938674 bkdAA Bacillus subtilis subsp. subtilis str. 168 2-oxoisovalerate dehydrogenase subunit alpha NP_390285.1 2499090 R 224308 CDS NP_390286.2 255767526 938669 complement(2500104..2501528) 1 NC_000964.3 E3 component of the branched-chain alpha-keto acid dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; dihydrolipoyl dehydrogenase 2501528 lpdV 938669 lpdV Bacillus subtilis subsp. subtilis str. 168 dihydrolipoyl dehydrogenase NP_390286.2 2500104 R 224308 CDS NP_390287.2 255767527 938675 complement(2501549..2502640) 1 NC_000964.3 catalyzes the phosphorylation of 2-butanoate to butanoyl phosphate; butyrate kinase 2502640 buk 938675 buk Bacillus subtilis subsp. subtilis str. 168 butyrate kinase NP_390287.2 2501549 R 224308 CDS NP_390288.1 16079464 938670 complement(2502659..2503753) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682; Product type e: enzyme; leucine dehydrogenase 2503753 bcd 938670 bcd Bacillus subtilis subsp. subtilis str. 168 leucine dehydrogenase NP_390288.1 2502659 R 224308 CDS NP_390289.2 255767528 938671 complement(2503765..2504664) 1 NC_000964.3 catalyzes the synthesis of butanoylphosphate from butanoyl-CoA and inorganic phosphate; phosphate butyryltransferase 2504664 ptb 938671 ptb Bacillus subtilis subsp. subtilis str. 168 phosphate butyryltransferase NP_390289.2 2503765 R 224308 CDS NP_390290.1 16079466 938666 complement(2504789..2506867) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10094682, 12427936, 15241682, 16585774; Product type r: regulator; sigma L-dependent transcriptional regulator YqiR 2506867 bkdR 938666 bkdR Bacillus subtilis subsp. subtilis str. 168 sigma L-dependent transcriptional regulator YqiR NP_390290.1 2504789 R 224308 CDS NP_390291.1 16079467 938667 2507020..2507256 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2507256 yqzF 938667 yqzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390291.1 2507020 D 224308 CDS NP_390292.1 16079468 938668 complement(2507298..2508203) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12706720; Product type e: enzyme; methylisocitrate lyase 2508203 prpB 938668 prpB Bacillus subtilis subsp. subtilis str. 168 methylisocitrate lyase NP_390292.1 2507298 R 224308 CDS NP_390293.2 255767529 938663 complement(2508221..2509639) 1 NC_000964.3 functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C; 2-methylcitrate dehydratase 2509639 prpD 938663 prpD Bacillus subtilis subsp. subtilis str. 168 2-methylcitrate dehydratase NP_390293.2 2508221 R 224308 CDS NP_390294.1 16079470 938665 complement(2509654..2510772) 1 NC_000964.3 forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle, glyoxylate cycle and respiration; 2-methylcitrate synthase 2510772 mmgD 938665 mmgD Bacillus subtilis subsp. subtilis str. 168 2-methylcitrate synthase NP_390294.1 2509654 R 224308 CDS NP_390295.2 255767530 938664 complement(2510806..2511945) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; acyl-CoA dehydrogenase 2511945 mmgC 938664 mmgC Bacillus subtilis subsp. subtilis str. 168 acyl-CoA dehydrogenase NP_390295.2 2510806 R 224308 CDS NP_390296.2 255767531 938660 complement(2511973..2512836) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8759838; Product type e: enzyme; 3-hydroxybutyryl-CoA dehydrogenase 2512836 mmgB 938660 mmgB Bacillus subtilis subsp. subtilis str. 168 3-hydroxybutyryl-CoA dehydrogenase NP_390296.2 2511973 R 224308 CDS NP_390297.1 16079473 938662 complement(2512861..2514042) 1 NC_000964.3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; acetyl-CoA acetyltransferase 2514042 mmgA 938662 mmgA Bacillus subtilis subsp. subtilis str. 168 acetyl-CoA acetyltransferase NP_390297.1 2512861 R 224308 CDS NP_390298.2 255767532 938661 complement(2514169..2514900) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2514900 yqiK 938661 yqiK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390298.2 2514169 R 224308 CDS NP_390299.2 255767533 938657 complement(2514979..2515599) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2515599 yqiI 938657 yqiI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390299.2 2514979 R 224308 CDS NP_390300.2 255767534 938658 complement(2515614..2515907) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 2515907 yqiH 938658 yqiH Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_390300.2 2515614 R 224308 CDS NP_390301.1 16079477 938659 2516440..2517558 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADH-dependent flavin oxidoreductase YqiG 2517558 yqiG 938659 yqiG Bacillus subtilis subsp. subtilis str. 168 NADH-dependent flavin oxidoreductase YqiG NP_390301.1 2516440 D 224308 CDS NP_390302.1 16079478 938655 complement(2518023..2518826) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12406209, 15556029, 15808745, 8504245; Product type r: regulator; stage 0 sporulation protein A 2518826 spo0A 938655 spo0A Bacillus subtilis subsp. subtilis str. 168 stage 0 sporulation protein A NP_390302.1 2518023 R 224308 CDS NP_390303.2 255767535 938654 complement(2519102..2520382) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12218026, 15292188, 16164552, 16238631, 16818230; Product type cp: cell process; peptidase S55 2520382 spoIVB 938654 spoIVB Bacillus subtilis subsp. subtilis str. 168 peptidase S55 NP_390303.2 2519102 R 224308 CDS NP_390304.2 255767536 938656 complement(2520557..2522287) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15186413, 15849320, 16061691, 16385024; Product type f: factor; DNA repair protein RecN 2522287 recN 938656 recN Bacillus subtilis subsp. subtilis str. 168 DNA repair protein RecN NP_390304.2 2520557 R 224308 CDS NP_390305.1 16079481 938653 complement(2522324..2522773) 1 NC_000964.3 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes; arginine repressor 2522773 ahrC 938653 ahrC Bacillus subtilis subsp. subtilis str. 168 arginine repressor NP_390305.1 2522324 R 224308 CDS NP_390306.2 255767537 938651 complement(2522871..2523716) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; rRNA methyltransferase YqxC 2523716 yqxC 938651 yqxC Bacillus subtilis subsp. subtilis str. 168 rRNA methyltransferase YqxC NP_390306.2 2522871 R 224308 CDS NP_390307.1 16079483 938609 complement(2523713..2525614) 1 NC_000964.3 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate; 1-deoxy-D-xylulose-5-phosphate synthase 2525614 dxs 938609 dxs Bacillus subtilis subsp. subtilis str. 168 1-deoxy-D-xylulose-5-phosphate synthase NP_390307.1 2523713 R 224308 CDS NP_390308.2 255767538 938652 complement(2525789..2526679) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17147392, 8755734; Product type e : enzyme; farnesyl diphosphate synthase 2526679 ispA 938652 ispA Bacillus subtilis subsp. subtilis str. 168 farnesyl diphosphate synthase NP_390308.2 2525789 R 224308 CDS NP_390309.2 255767539 938649 complement(2526669..2526923) 1 NC_000964.3 catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease 7 small subunit 2526923 xseB 938649 xseB Bacillus subtilis subsp. subtilis str. 168 exodeoxyribonuclease 7 small subunit NP_390309.2 2526669 R 224308 CDS NP_390310.2 255767540 938650 complement(2526920..2528266) 1 NC_000964.3 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease 7 large subunit 2528266 xseA 938650 xseA Bacillus subtilis subsp. subtilis str. 168 exodeoxyribonuclease 7 large subunit NP_390310.2 2526920 R 224308 CDS NP_390311.1 16079487 938602 complement(2528404..2529255) 1 NC_000964.3 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional protein FolD 2529255 folD 938602 folD Bacillus subtilis subsp. subtilis str. 168 bifunctional protein FolD NP_390311.1 2528404 R 224308 CDS NP_390312.2 255767541 938606 complement(2529267..2529662) 1 NC_000964.3 Regulates rRNA biosynthesis by transcriptional antitermination; N utilization substance protein B homolog 2529662 nusB 938606 nusB Bacillus subtilis subsp. subtilis str. 168 N utilization substance protein B homolog NP_390312.2 2529267 R 224308 CDS NP_390313.2 255767542 938598 complement(2529926..2530333) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16014871, 17114254; hypothetical protein 2530333 yqhY 938598 yqhY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390313.2 2529926 R 224308 CDS NP_390314.2 255767543 938588 complement(2530354..2531706) 1 NC_000964.3 an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxylase 1 2531706 accC 938588 accC Bacillus subtilis subsp. subtilis str. 168 biotin carboxylase 1 NP_390314.2 2530354 R 224308 CDS NP_390315.1 16079491 938587 complement(2531718..2532197) 1 NC_000964.3 composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; biotin carboxyl carrier protein of acetyl-CoA carboxylase 2532197 accB 938587 accB Bacillus subtilis subsp. subtilis str. 168 biotin carboxyl carrier protein of acetyl-CoA carboxylase NP_390315.1 2531718 R 224308 CDS NP_390316.2 255767544 938600 complement(2532353..2533009) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15752199, 16959571, 1766372; Product type cp: cell process; stage III sporulation protein AH 2533009 spoIIIAH 938600 spoIIIAH Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AH NP_390316.2 2532353 R 224308 CDS NP_390317.2 255767545 938595 complement(2533010..2533699) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AG 2533699 spoIIIAG 938595 spoIIIAG Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AG NP_390317.2 2533010 R 224308 CDS NP_390318.1 16079494 938576 complement(2533692..2534312) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AF 2534312 spoIIIAF 938576 spoIIIAF Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AF NP_390318.1 2533692 R 224308 CDS NP_390319.2 255767546 938569 complement(2534326..2535525) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process; stage III sporulation protein AE 2535525 spoIIIAE 938569 spoIIIAE Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AE NP_390319.2 2534326 R 224308 CDS NP_390320.1 16079496 938577 complement(2535544..2535945) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 15849754, 16850406, 1766372; Product type cp: cell process; stage III sporulation protein AD 2535945 spoIIIAD 938577 spoIIIAD Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AD NP_390320.1 2535544 R 224308 CDS NP_390321.1 16079497 938562 complement(2535952..2536158) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AC 2536158 spoIIIAC 938562 spoIIIAC Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AC NP_390321.1 2535952 R 224308 CDS NP_390322.1 16079498 938561 complement(2536181..2536696) 1 NC_000964.3 necessary for complete engulfment of forespore; stage III sporulation protein AB 2536696 spoIIIAB 938561 spoIIIAB Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AB NP_390322.1 2536181 R 224308 CDS NP_390323.1 16079499 938563 complement(2536690..2537613) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15028710, 1766372; Product type cp: cell process; stage III sporulation protein AA 2537613 spoIIIAA 938563 spoIIIAA Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein AA NP_390323.1 2536690 R 224308 CDS NP_390324.1 16079500 938559 complement(2537689..2537970) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2537970 yqhV 938559 yqhV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390324.1 2537689 R 224308 CDS NP_390325.2 255767547 938558 complement(2538115..2538672) 1 NC_000964.3 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P 2538672 efp 938558 efp Bacillus subtilis subsp. subtilis str. 168 elongation factor P NP_390325.2 2538115 R 224308 CDS NP_390326.1 16079502 938560 complement(2538697..2539758) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YqhT 2539758 yqhT 938560 yqhT Bacillus subtilis subsp. subtilis str. 168 peptidase YqhT NP_390326.1 2538697 R 224308 CDS NP_390327.1 16079503 938557 complement(2539755..2540201) 1 NC_000964.3 catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis; 3-dehydroquinate dehydratase 2540201 yqhS 938557 yqhS Bacillus subtilis subsp. subtilis str. 168 3-dehydroquinate dehydratase NP_390327.1 2539755 R 224308 CDS NP_390328.1 16079504 938555 complement(2540288..2540824) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2540824 yqhR 938555 yqhR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390328.1 2540288 R 224308 CDS NP_390329.2 255767548 938556 2541051..2542007 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2542007 yqhQ 938556 yqhQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390329.2 2541051 D 224308 CDS NP_390330.1 16079506 938552 2542047..2542442 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2542442 yqhP 938552 yqhP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390330.1 2542047 D 224308 CDS NP_390331.1 16079507 938553 complement(2542439..2543314) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2543314 yqhO 938553 yqhO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390331.1 2542439 R 224308 CDS NP_390332.2 255767549 938554 complement(2543440..2543868) 1 NC_000964.3 involved in manganese homeostasis; activates the transcription of the mntABCD operon; transcriptional regulator MntR 2543868 mntR 938554 mntR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator MntR NP_390332.2 2543440 R 224308 CDS NP_390333.1 16079509 938551 complement(2543968..2544804) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; octanoyltransferase LipM 2544804 yqhM 938551 yqhM Bacillus subtilis subsp. subtilis str. 168 octanoyltransferase LipM NP_390333.1 2543968 R 224308 CDS NP_390334.2 255767550 938550 2544995..2545375 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11092948; Product type pe : enzyme; hypothetical protein 2545375 yqhL 938550 yqhL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390334.2 2544995 D 224308 CDS NP_390335.1 16079511 938549 complement(2545410..2546876) 1 NC_000964.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 1 to form the P protein; glycine dehydrogenase subunit 2 2546876 gcvPB 938549 gcvPB Bacillus subtilis subsp. subtilis str. 168 glycine dehydrogenase subunit 2 NP_390335.1 2545410 R 224308 CDS NP_390336.2 255767551 938546 complement(2546869..2548215) 1 NC_000964.3 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine; forms a heterodimer with subunit 2 to form the P protein; glycine dehydrogenase subunit 1 2548215 gcvPA 938546 gcvPA Bacillus subtilis subsp. subtilis str. 168 glycine dehydrogenase subunit 1 NP_390336.2 2546869 R 224308 CDS NP_390337.2 255767552 938547 complement(2548245..2549333) 1 NC_000964.3 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; aminomethyltransferase 2549333 gcvT 938547 gcvT Bacillus subtilis subsp. subtilis str. 168 aminomethyltransferase NP_390337.2 2548245 R 224308 CDS NP_390338.1 16079514 938548 2549775..2551448 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATP-dependent helicase YqhH 2551448 yqhH 938548 yqhH Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase YqhH NP_390338.1 2549775 D 224308 CDS NP_390339.1 16079515 938541 2551469..2552263 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2552263 yqhG 938541 yqhG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390339.1 2551469 D 224308 CDS NP_390340.1 16079516 938543 2552446..2552619 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10547280, 11751836, 15661000, 15805512, 8549812; Product type r: regulator; SinR antagonist SinI 2552619 sinI 938543 sinI Bacillus subtilis subsp. subtilis str. 168 SinR antagonist SinI NP_390340.1 2552446 D 224308 CDS NP_390341.1 16079517 938544 2552653..2552988 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15805512, 16585769, 16740951, 16923912; Product type r: regulator; XRE family transcriptional regulator 2552988 sinR 938544 sinR Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_390341.1 2552653 D 224308 CDS NP_390342.1 16079518 938545 complement(2553081..2553866) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10827084, 16430695, 16430696, 18047568; Product type cp: cell process; spore coat protein N 2553866 tasA 938545 tasA Bacillus subtilis subsp. subtilis str. 168 spore coat protein N NP_390342.1 2553081 R 224308 CDS NP_390343.1 16079519 938542 complement(2553930..2554502) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 10827084, 15101989, 16430695; Product type e: enzyme; signal peptidase I W 2554502 sipW 938542 sipW Bacillus subtilis subsp. subtilis str. 168 signal peptidase I W NP_390343.1 2553930 R 224308 CDS NP_390344.1 16079520 938532 complement(2554486..2555247) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10464223, 10559173, 14707086, 16430695, 17554552; Product type lp : lipoprotein; hypothetical protein 2555247 yqxM 938532 yqxM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390344.1 2554486 R 224308 CDS NP_390345.1 16079521 938529 2555519..2555845 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 2555845 yqzG 938529 yqzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390345.1 2555519 D 224308 CDS NP_390346.2 255767553 938540 complement(2555887..2556066) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2556066 yqzE 938540 yqzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390346.2 2555887 R 224308 CDS NP_390347.1 16079523 938538 complement(2556137..2556511) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 7 2556511 comGG 938538 comGG Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 7 NP_390347.1 2556137 R 224308 CDS NP_390348.1 16079524 938530 complement(2556512..2556895) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 6 2556895 comGF 938530 comGF Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 6 NP_390348.1 2556512 R 224308 CDS NP_390349.1 16079525 938518 complement(2556921..2557268) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 7783624, 9224890, 9422590, 9723928; Product type cp: cell process; ComG operon protein 5 2557268 comGE 938518 comGE Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 5 NP_390349.1 2556921 R 224308 CDS NP_390350.1 16079526 938531 complement(2557252..2557683) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195, 9224890, 9422590, 9723928; Product type cp: cell process; ComG operon protein 4 2557683 comGD 938531 comGD Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 4 NP_390350.1 2557252 R 224308 CDS NP_390351.1 16079527 938526 complement(2557673..2557969) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 16751195, 7783624, 9723928; Product type cp: cell process; ComG operon protein 3 2557969 comGC 938526 comGC Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 3 NP_390351.1 2557673 R 224308 CDS NP_390352.1 16079528 938527 complement(2557983..2558954) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9150204, 9723928; Product type cp: cell process; ComG operon protein 2 2558954 comGB 938527 comGB Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 2 NP_390352.1 2557983 R 224308 CDS NP_390353.1 16079529 938516 complement(2559007..2560077) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11298275, 15528548, 16009134, 9723928; Product type cp: cell process; ComG operon protein 1 2560077 comGA 938516 comGA Bacillus subtilis subsp. subtilis str. 168 ComG operon protein 1 NP_390353.1 2559007 R 224308 CDS NP_390354.1 16079530 938517 complement(2560489..2561442) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15856219; Product type pt : transporter; magnesium transport protein CorA 2561442 yqxL 938517 yqxL Bacillus subtilis subsp. subtilis str. 168 magnesium transport protein CorA NP_390354.1 2560489 R 224308 CDS NP_390355.1 16079531 938492 2561585..2562913 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 2562913 yqhB 938492 yqhB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390355.1 2561585 D 224308 CDS NP_390356.2 255767554 938513 complement(2562966..2563802) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15312768, 15583165, 16963570, 17158665, 11157946; Product type f: factor; RsbT co-antagonist protein RsbRD 2563802 rsbRD 938513 rsbRD Bacillus subtilis subsp. subtilis str. 168 RsbT co-antagonist protein RsbRD NP_390356.2 2562966 R 224308 CDS NP_390357.2 255767555 938484 complement(2564026..2564406) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18643936; Product type r: regulator; regulatory protein MgsR 2564406 mgsR 938484 mgsR Bacillus subtilis subsp. subtilis str. 168 regulatory protein MgsR NP_390357.2 2564026 R 224308 CDS NP_390358.1 16079534 938215 2564638..2564883 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2564883 yqgY 938215 yqgY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390358.1 2564638 D 224308 CDS NP_390359.1 16079535 938218 complement(2564923..2565558) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2565558 yqgX 938218 yqgX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390359.1 2564923 R 224308 CDS NP_390360.1 16079536 938217 2565715..2565888 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2565888 yqgW 938217 yqgW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390360.1 2565715 D 224308 CDS NP_390361.2 255767556 938212 complement(2565920..2566234) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2566234 yqgV 938212 yqgV Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390361.2 2565920 R 224308 CDS NP_390362.2 255767557 938213 complement(2566237..2567298) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 2567298 yqgU 938213 yqgU Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_390362.2 2566237 R 224308 CDS NP_390363.1 16079539 938214 complement(2567360..2568490) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12765833; Product type pe : enzyme; hypothetical protein 2568490 yqgT 938214 yqgT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390363.1 2567360 R 224308 CDS NP_390364.2 255767558 938209 complement(2568573..2570489) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; lipoteichoic acid synthase 2570489 yqgS 938209 yqgS Bacillus subtilis subsp. subtilis str. 168 lipoteichoic acid synthase NP_390364.2 2568573 R 224308 CDS NP_390365.2 255767559 938206 complement(2570606..2571571) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15018644, 15050034, 9620975; Product type e: enzyme; glucokinase 2571571 glcK 938206 glcK Bacillus subtilis subsp. subtilis str. 168 glucokinase NP_390365.2 2570606 R 224308 CDS NP_390366.1 16079542 938210 complement(2571582..2571797) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15050034; hypothetical protein 2571797 yqgQ 938210 yqgQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390366.1 2571582 R 224308 CDS NP_390367.2 255767560 938211 complement(2571907..2573430) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15050034, 16355228; Product type e: enzyme; rhomboid protease GluP 2573430 glpG 938211 glpG Bacillus subtilis subsp. subtilis str. 168 rhomboid protease GluP NP_390367.2 2571907 R 224308 CDS NP_390368.1 16079544 938204 complement(2573520..2573693) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2573693 yqgO 938204 yqgO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390368.1 2573520 R 224308 CDS NP_390369.1 16079545 938208 complement(2573760..2574323) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17329806; Product type e: enzyme; hypothetical protein 2574323 yqgN 938208 yqgN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390369.1 2573760 R 224308 CDS NP_570908.2 255767561 937959 complement(2574408..2574557) 1 NC_000964.3 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 1 2574557 rpmG 937959 rpmG Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L33 1 NP_570908.2 2574408 R 224308 CDS NP_390370.2 255767562 938207 complement(2574641..2575720) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YqgM 2575720 yqgM 938207 yqgM Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YqgM NP_390370.2 2574641 R 224308 CDS NP_390371.1 16079547 938201 complement(2575717..2576187) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2576187 yqgL 938201 yqgL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390371.1 2575717 R 224308 CDS NP_390372.1 16079548 938203 2576367..2576720 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2576720 yqzD 938203 yqzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390372.1 2576367 D 224308 CDS NP_390373.2 255767563 938202 2576717..2577181 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2577181 yqzC 938202 yqzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390373.2 2576717 D 224308 CDS NP_390374.1 16079550 938205 complement(2577210..2577992) 1 NC_000964.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate import ATP-binding protein PstB 1 2577992 pstBB 938205 pstBB Bacillus subtilis subsp. subtilis str. 168 phosphate import ATP-binding protein PstB 1 NP_390374.1 2577210 R 224308 CDS NP_390375.1 16079551 938198 complement(2578003..2578812) 1 NC_000964.3 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate import ATP-binding protein PstB 2 2578812 pstBA 938198 pstBA Bacillus subtilis subsp. subtilis str. 168 phosphate import ATP-binding protein PstB 2 NP_390375.1 2578003 R 224308 CDS NP_390376.2 255767564 938200 complement(2578833..2579717) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter; ABC transporter permease 2579717 pstA 938200 pstA Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390376.2 2578833 R 224308 CDS NP_390377.2 255767565 938184 complement(2579717..2580646) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897025, 15289558, 15849754, 16850406, 9098050; Product type t : transporter; ABC transporter permease 2580646 pstC 938184 pstC Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390377.2 2579717 R 224308 CDS NP_390378.1 16079554 938197 complement(2580715..2581617) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 15289558, 9098050, 9593301; Product type t: transporter; phosphate-binding protein PstS 2581617 pstS 938197 pstS Bacillus subtilis subsp. subtilis str. 168 phosphate-binding protein PstS NP_390378.1 2580715 R 224308 CDS NP_390379.1 16079555 938199 complement(2581771..2583921) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12896990, 9139922, 9851991; Product type e: enzyme; hypothetical protein 2583921 pbpA 938199 pbpA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390379.1 2581771 R 224308 CDS NP_390380.2 255767566 938196 complement(2584035..2585327) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pt: transporter; hypothetical protein 2585327 yqgE 938196 yqgE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390380.2 2584035 R 224308 CDS NP_390381.3 255767567 938052 complement(2585434..2586042) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074093, 15897454, 18084079, 9393707, 9573176, 9658017; Product type e : enzyme; superoxide dismutase 2586042 sodA 938052 sodA Bacillus subtilis subsp. subtilis str. 168 superoxide dismutase NP_390381.3 2585434 R 224308 CDS NP_390382.1 16079558 938138 complement(2586221..2586703) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2586703 yqgC 938138 yqgC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390382.1 2586221 R 224308 CDS NP_390383.2 255767568 937983 2586813..2587580 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype; hypothetical protein 2587580 yqgB 937983 yqgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390383.2 2586813 D 224308 CDS NP_390384.2 255767569 937963 complement(2587996..2588424) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; cell wall-binding protein YqgA 2588424 yqgA 937963 yqgA Bacillus subtilis subsp. subtilis str. 168 cell wall-binding protein YqgA NP_390384.2 2587996 R 224308 CDS NP_390385.1 16079561 938027 2588701..2589000 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15294815; Product type ph: phenotype; hypothetical protein 2589000 yqfZ 938027 yqfZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390385.1 2588701 D 224308 CDS NP_390386.1 16079562 937984 2589123..2590256 1 NC_000964.3 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2590256 ispG 937984 ispG Bacillus subtilis subsp. subtilis str. 168 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase NP_390386.1 2589123 D 224308 CDS NP_390387.1 16079563 937973 complement(2590282..2590671) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2590671 yqfX 937973 yqfX Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390387.1 2590282 R 224308 CDS NP_390388.1 16079564 937915 2590804..2591385 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; nucleotidase YqfW 2591385 yqfW 937915 yqfW Bacillus subtilis subsp. subtilis str. 168 nucleotidase YqfW NP_390388.1 2590804 D 224308 CDS NP_390389.2 255767570 937968 complement(2591428..2591865) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12180919, 12426338, 12904577, 17216355; Product type r: regulator; zinc-specific metallo-regulatory protein 2591865 zur 937968 zur Bacillus subtilis subsp. subtilis str. 168 zinc-specific metallo-regulatory protein NP_390389.2 2591428 R 224308 CDS NP_390390.2 255767571 937944 complement(2592003..2592884) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2592884 yqfU 937944 yqfU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390390.2 2592003 R 224308 CDS NP_390391.1 16079567 937909 2593000..2593254 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2593254 yqfT 937909 yqfT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390391.1 2593000 D 224308 CDS NP_390392.1 16079568 937922 complement(2593281..2594174) 1 NC_000964.3 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues; endonuclease IV 2594174 yqfS 937922 yqfS Bacillus subtilis subsp. subtilis str. 168 endonuclease IV NP_390392.1 2593281 R 224308 CDS NP_390393.1 16079569 937908 complement(2594184..2595500) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16014871, 16352840, 18203828; Product type e: enzyme; DEAD/DEAH box helicase 2595500 cshB 937908 cshB Bacillus subtilis subsp. subtilis str. 168 DEAD/DEAH box helicase NP_390393.1 2594184 R 224308 CDS NP_390394.1 16079570 937910 2595669..2596412 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2596412 yqfQ 937910 yqfQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390394.1 2595669 D 224308 CDS NP_390395.2 255767572 937900 2596535..2597479 1 NC_000964.3 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 2597479 ispH 937900 ispH Bacillus subtilis subsp. subtilis str. 168 4-hydroxy-3-methylbut-2-enyl diphosphate reductase NP_390395.2 2596535 D 224308 CDS NP_390396.1 16079572 937901 complement(2597502..2598623) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2598623 yqfO 937901 yqfO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390396.1 2597502 R 224308 CDS NP_390397.1 16079573 937898 complement(2598616..2599266) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18420655; Product type e: enzyme; tRNA: m1A22 methyltransferase 2599266 trmK 937898 trmK Bacillus subtilis subsp. subtilis str. 168 tRNA: m1A22 methyltransferase NP_390397.1 2598616 R 224308 CDS NP_390398.1 16079574 937902 complement(2599523..2599885) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10024472, 10473570, 11361075, 15995641; Product type c: carrier; cytochrome c-550 2599885 cccA 937902 cccA Bacillus subtilis subsp. subtilis str. 168 cytochrome c-550 NP_390398.1 2599523 R 224308 CDS NP_390399.2 255767573 937897 complement(2600214..2601329) 1 NC_000964.3 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD 2601329 sigA 937897 sigA Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor RpoD NP_390399.2 2600214 R 224308 CDS NP_390400.2 255767574 937899 complement(2601528..2603339) 1 NC_000964.3 synthesizes RNA primers at the replication forks; DNA primase 2603339 dnaG 937899 dnaG Bacillus subtilis subsp. subtilis str. 168 DNA primase NP_390400.2 2601528 R 224308 CDS YP_054587.1 50812269 2914189 2602979..2603275 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 9864351; protein AntE 2603275 antE 2914189 antE Bacillus subtilis subsp. subtilis str. 168 protein AntE YP_054587.1 2602979 D 224308 CDS NP_390401.2 255767575 937896 complement(2603373..2603867) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 9387153; hypothetical protein 2603867 yqxD 937896 yqxD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390401.2 2603373 R 224308 CDS NP_390402.1 16079578 937889 complement(2604121..2604933) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator; hypothetical protein 2604933 yqfL 937889 yqfL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390402.1 2604121 R 224308 CDS NP_390403.1 16079579 937886 complement(2604959..2605597) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15720552; Product type r: regulator; transcriptional repressor CcpN 2605597 ccpN 937886 ccpN Bacillus subtilis subsp. subtilis str. 168 transcriptional repressor CcpN NP_390403.1 2604959 R 224308 CDS NP_390404.2 255767576 937887 complement(2605730..2607769) 1 NC_000964.3 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycine--tRNA ligase beta subunit 2607769 glyS 937887 glyS Bacillus subtilis subsp. subtilis str. 168 glycine--tRNA ligase beta subunit NP_390404.2 2605730 R 224308 CDS NP_390405.1 16079581 937888 complement(2607762..2608649) 1 NC_000964.3 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycine--tRNA ligase alpha subunit 2608649 glyQ 937888 glyQ Bacillus subtilis subsp. subtilis str. 168 glycine--tRNA ligase alpha subunit NP_390405.1 2607762 R 224308 CDS NP_390406.2 255767577 937881 complement(2608946..2609713) 1 NC_000964.3 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 2609713 recO 937881 recO Bacillus subtilis subsp. subtilis str. 168 DNA repair protein RecO NP_390406.2 2608946 R 224308 CDS YP_003097761.1 255767578 8303204 complement(2609750..2609893) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2609893 yqzL 8303204 yqzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097761.1 2609750 R 224308 CDS NP_390407.1 16079583 937871 complement(2610041..2610946) 1 NC_000964.3 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTPase Era 2610946 era 937871 era Bacillus subtilis subsp. subtilis str. 168 GTPase Era NP_390407.1 2610041 R 224308 CDS NP_390408.1 16079584 937885 complement(2610927..2611337) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10217788, 2526291, 8157589; Product type e: enzyme; cytidine deaminase 2611337 cdd 937885 cdd Bacillus subtilis subsp. subtilis str. 168 cytidine deaminase NP_390408.1 2610927 R 224308 CDS NP_390409.2 255767579 937873 complement(2611456..2611827) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12923107, 17535816; Product type e: enzyme; undecaprenol kinase 2611827 dgkA 937873 dgkA Bacillus subtilis subsp. subtilis str. 168 undecaprenol kinase NP_390409.2 2611456 R 224308 CDS NP_390410.2 255767580 937869 complement(2611808..2612281) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metalloprotease 2612281 yqfG 937869 yqfG Bacillus subtilis subsp. subtilis str. 168 metalloprotease NP_390410.2 2611808 R 224308 CDS NP_390411.1 16079587 937877 complement(2612282..2614417) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16751502; Product type pe : enzyme; hypothetical protein 2614417 yqfF 937877 yqfF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390411.1 2612282 R 224308 CDS NP_390412.2 255767581 937868 complement(2614496..2615455) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12762842; Product type ph: phenotype; PhoH-like protein 2615455 phoH 937868 phoH Bacillus subtilis subsp. subtilis str. 168 PhoH-like protein NP_390412.2 2614496 R 224308 CDS NP_390413.2 255767582 937867 complement(2615452..2616648) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14523133; Product type cp: cell process; hypothetical protein 2616648 yqfD 937867 yqfD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390413.2 2615452 R 224308 CDS NP_390414.1 16079590 937870 complement(2616667..2616948) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922; hypothetical protein 2616948 yqfC 937870 yqfC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390414.1 2616667 R 224308 CDS NP_390415.2 255767583 937864 complement(2617005..2617424) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2617424 yqfB 937864 yqfB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390415.2 2617005 R 224308 CDS NP_390416.1 16079592 937865 complement(2617449..2618444) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12501411; Product type cp : cell process; hypothetical protein 2618444 yqfA 937865 yqfA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390416.1 2617449 R 224308 CDS NP_390417.1 16079593 937859 complement(2618466..2619779) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2619779 yqeZ 937859 yqeZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390417.1 2618466 R 224308 CDS NP_390418.1 16079594 937860 complement(2619910..2620356) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2620356 yqeY 937860 yqeY Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390418.1 2619910 R 224308 CDS NP_390419.1 16079595 937861 complement(2620371..2620544) 1 NC_000964.3 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 2620544 rpsU 937861 rpsU Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S21 NP_390419.1 2620371 R 224308 CDS NP_390420.2 255767584 937858 2620717..2621640 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 2621640 yqeW 937858 yqeW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390420.2 2620717 D 224308 CDS NP_390421.1 16079597 937857 complement(2621677..2623032) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10572129, 15339930, 18252828, 8844851; Product type e: enzyme; threonylcarbamoyladenosine tRNA methylthiotransferase MtaB 2623032 rimO 937857 rimO Bacillus subtilis subsp. subtilis str. 168 threonylcarbamoyladenosine tRNA methylthiotransferase MtaB NP_390421.1 2621677 R 224308 CDS NP_390422.1 16079598 937856 complement(2623032..2623802) 1 NC_000964.3 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; ribosomal RNA small subunit methyltransferase E 2623802 yqeU 937856 yqeU Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase E NP_390422.1 2623032 R 224308 CDS NP_390423.2 255767585 937847 complement(2623825..2624760) 1 NC_000964.3 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; ribosomal protein L11 methyltransferase 2624760 prmA 937847 prmA Bacillus subtilis subsp. subtilis str. 168 ribosomal protein L11 methyltransferase NP_390423.2 2623825 R 224308 CDS NP_390424.2 255767586 937848 complement(2624785..2625912) 1 NC_000964.3 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 2625912 dnaJ 937848 dnaJ Bacillus subtilis subsp. subtilis str. 168 chaperone protein DnaJ NP_390424.2 2624785 R 224308 CDS NP_390425.1 16079601 937849 complement(2626112..2627947) 1 NC_000964.3 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; chaperone protein DnaK 2627947 dnaK 937849 dnaK Bacillus subtilis subsp. subtilis str. 168 chaperone protein DnaK NP_390425.1 2626112 R 224308 CDS NP_390426.1 16079602 937846 complement(2627971..2628534) 1 NC_000964.3 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 2628534 grpE 937846 grpE Bacillus subtilis subsp. subtilis str. 168 heat shock protein GrpE NP_390426.1 2627971 R 224308 CDS NP_390427.1 16079603 937843 complement(2628606..2629637) 1 NC_000964.3 Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor HrcA 2629637 hrcA 937843 hrcA Bacillus subtilis subsp. subtilis str. 168 heat-inducible transcription repressor HrcA NP_390427.1 2628606 R 224308 CDS NP_390428.2 255767587 937845 complement(2629718..2630857) 1 NC_000964.3 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; oxygen-independent coproporphyrinogen-III oxidase 1 2630857 hemN 937845 hemN Bacillus subtilis subsp. subtilis str. 168 oxygen-independent coproporphyrinogen-III oxidase 1 NP_390428.2 2629718 R 224308 CDS NP_390429.1 16079605 937840 complement(2630910..2632748) 1 NC_000964.3 binds to the ribosome on the universally-conserved alpha-sarcin loop; elongation factor 4 2632748 lepA 937840 lepA Bacillus subtilis subsp. subtilis str. 168 elongation factor 4 NP_390429.1 2630910 R 224308 CDS NP_390430.1 16079606 937841 complement(2632882..2633220) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2633220 yqxA 937841 yqxA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390430.1 2632882 R 224308 CDS NP_390431.1 16079607 937842 complement(2633237..2634442) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17376078; Product type cp: cell process; stage II sporulation protein P 2634442 spoIIP 937842 spoIIP Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein P NP_390431.1 2633237 R 224308 CDS NP_390432.1 16079608 937838 complement(2634505..2635611) 1 NC_000964.3 Initiates the rapid degradation of small acid-soluble proteins during spore germination; germination protease 2635611 gpr 937838 gpr Bacillus subtilis subsp. subtilis str. 168 germination protease NP_390432.1 2634505 R 224308 CDS NP_390433.2 255767588 937837 2635815..2636081 1 NC_000964.3 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 2636081 rpsT 937837 rpsT Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S20 NP_390433.2 2635815 D 224308 CDS NP_390434.1 16079610 937833 complement(2636096..2637139) 1 NC_000964.3 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; hypothetical protein 2637139 holA 937833 holA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390434.1 2636096 R 224308 CDS YP_003097762.1 255767589 8303117 2637369..2637503 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2637503 yqzM 8303117 yqzM Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097762.1 2637369 D 224308 CDS NP_390435.1 16079611 937839 complement(2637543..2639873) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12123453, 15661011, 16751195; Product type cp: cell process; ComE operon protein 3 2639873 comEC 937839 comEC Bacillus subtilis subsp. subtilis str. 168 ComE operon protein 3 NP_390435.1 2637543 R 224308 CDS NP_390436.1 16079612 937832 complement(2639877..2640446) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7768800; Product type cp : cell process; ComE operon protein 2 2640446 comEB 937832 comEB Bacillus subtilis subsp. subtilis str. 168 ComE operon protein 2 NP_390436.1 2639877 R 224308 CDS NP_390437.1 16079613 937827 complement(2640513..2641130) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16751195; Product type cp: cell process; ComE operon protein 1 2641130 comEA 937827 comEA Bacillus subtilis subsp. subtilis str. 168 ComE operon protein 1 NP_390437.1 2640513 R 224308 CDS NP_390438.1 16079614 937834 2641214..2642035 1 NC_000964.3 may be involved in regulation of competence genes; ComE operon protein 4 2642035 comER 937834 comER Bacillus subtilis subsp. subtilis str. 168 ComE operon protein 4 NP_390438.1 2641214 D 224308 CDS NP_390439.1 16079615 937826 complement(2642101..2642844) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; methyltransferase 2642844 yqeM 937826 yqeM Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_390439.1 2642101 R 224308 CDS NP_390440.1 16079616 937819 complement(2642841..2643197) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2643197 yqeL 937819 yqeL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390440.1 2642841 R 224308 CDS NP_390441.1 16079617 937831 complement(2643215..2643775) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311; Product type pe : enzyme; hypothetical protein 2643775 yqeK 937831 yqeK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390441.1 2643215 R 224308 CDS NP_390442.1 16079618 937818 complement(2643765..2644334) 1 NC_000964.3 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinate-nucleotide adenylyltransferase 2644334 nadD 937818 nadD Bacillus subtilis subsp. subtilis str. 168 nicotinate-nucleotide adenylyltransferase NP_390442.1 2643765 R 224308 CDS NP_390443.1 16079619 937813 complement(2644346..2644636) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 17005971, 17105995; Product type pf: factor; RNA-binding protein YqeI 2644636 yqeI 937813 yqeI Bacillus subtilis subsp. subtilis str. 168 RNA-binding protein YqeI NP_390443.1 2644346 R 224308 CDS NP_390444.2 255767590 937820 complement(2644630..2645472) 1 NC_000964.3 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate dehydrogenase 2645472 aroE 937820 aroE Bacillus subtilis subsp. subtilis str. 168 shikimate dehydrogenase NP_390444.2 2644630 R 224308 CDS NP_390445.1 16079621 937822 complement(2645490..2646590) 1 NC_000964.3 in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; hypothetical protein 2646590 yqeH 937822 yqeH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390445.1 2645490 R 224308 CDS NP_390446.1 16079622 937815 complement(2646594..2647112) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2647112 yqeG 937815 yqeG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390446.1 2646594 R 224308 CDS YP_054588.1 50812270 2914223 2647456..2647614 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15023339, 16796683, 19040634; Product type f: factor; sporulation inhibitor sda 2647614 sda 2914223 sda Bacillus subtilis subsp. subtilis str. 168 sporulation inhibitor sda YP_054588.1 2647456 D 224308 CDS NP_390447.1 16079623 937814 complement(2647920..2648651) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipoprotein 2648651 yqeF 937814 yqeF Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_390447.1 2647920 R 224308 CDS NP_390448.1 16079624 937808 complement(2648903..2649655) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10515909, 10974124, 15687192; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase CwlH 2649655 cwlH 937808 cwlH Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase CwlH NP_390448.1 2648903 R 224308 CDS NP_390449.1 16079625 937812 2649842..2650468 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15849754, 15855514, 16850406; hypothetical protein 2650468 yqeD 937812 yqeD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390449.1 2649842 D 224308 CDS NP_390450.1 16079626 937809 complement(2650487..2651380) 1 NC_000964.3 similar to full-length Gnd, these proteins seems to have a truncated C-terminal 6PGD domainin; in Methylobacillus flagellatus this gene is essential for NAD+-dependent oxidation of 6-phosphogluconate; 6-phosphogluconate dehydrogenase YqeC 2651380 yqeC 937809 yqeC Bacillus subtilis subsp. subtilis str. 168 6-phosphogluconate dehydrogenase YqeC NP_390450.1 2650487 R 224308 CDS NP_390451.2 255767591 937802 2651632..2652354 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2652354 yqeB 937802 yqeB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390451.2 2651632 D 224308 CDS NP_390452.1 16079628 937804 complement(2652387..2652797) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17209033, 7746143; Product type e: enzyme; sporulation-specific extracellular nuclease 2652797 nucB 937804 nucB Bacillus subtilis subsp. subtilis str. 168 sporulation-specific extracellular nuclease NP_390452.1 2652387 R 224308 CDS NP_390454.2 255767592 937799 complement(2653371..2654873) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1631085, 2163341, 7704261, 8300549, 8969508; Product type e: enzyme; DNA recombinase 2654873 spoIVCA 937799 spoIVCA Bacillus subtilis subsp. subtilis str. 168 DNA recombinase NP_390454.2 2653371 R 224308 CDS NP_390455.1 16079631 937801 complement(2655322..2655741) 1 NC_000964.3 catalyzes the reduction of arsenate to arsenite; also can dephosphorylate tyrosine phosphorylated proteins, aryl phosphates, and acyl phosphates; arsenate reductase ArsC 2655741 arsC 937801 arsC Bacillus subtilis subsp. subtilis str. 168 arsenate reductase ArsC NP_390455.1 2655322 R 224308 CDS NP_390456.2 255767593 937800 complement(2655753..2656793) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 16905151, 9537360; Product type t: transporter; arsenite resistance protein ArsB 2656793 arsB 937800 arsB Bacillus subtilis subsp. subtilis str. 168 arsenite resistance protein ArsB NP_390456.2 2655753 R 224308 CDS NP_390457.2 255767594 937794 complement(2656816..2657256) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16905151, 8760915, 8969508, 9537360; Product type pe: enzyme; hypothetical protein 2657256 yqcK 937794 yqcK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390457.2 2656816 R 224308 CDS NP_390458.1 16079634 937789 complement(2657317..2657634) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537360; Product type r : regulator; arsenical resistance operon repressor 2657634 arsR 937789 arsR Bacillus subtilis subsp. subtilis str. 168 arsenical resistance operon repressor NP_390458.1 2657317 R 224308 CDS NP_390459.2 255767595 937795 complement(2658006..2658770) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8760915, 8969508; Product type h : extrachromosomal origin; hypothetical protein 2658770 yqcI 937795 yqcI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390459.2 2658006 R 224308 CDS NP_390460.2 255767596 937796 2659213..2660340 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10629174, 11679073, 12897006, 8760915, 8969508; Product type r: regulator; response regulator aspartate phosphatase E 2660340 rapE 937796 rapE Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase E NP_390460.2 2659213 D 224308 CDS NP_390461.1 16079637 937784 2660330..2660464 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174; Product type r: regulator; phosphatase RapE inhibitor 2660464 phrE 937784 phrE Bacillus subtilis subsp. subtilis str. 168 phosphatase RapE inhibitor NP_390461.1 2660330 D 224308 CDS NP_390462.1 16079638 937791 2660574..2660732 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2660732 yqzI 937791 yqzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390462.1 2660574 D 224308 CDS NP_390463.1 16079639 937792 2661102..2662697 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2662697 yqcG 937792 yqcG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390463.1 2661102 D 224308 CDS NP_390464.1 16079640 937785 2662712..2663290 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2663290 yqcF 937785 yqcF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390464.1 2662712 D 224308 CDS NP_390465.1 16079641 937786 complement(2663551..2663913) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2663913 yqxJ 937786 yqxJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390465.1 2663551 R 224308 CDS NP_390466.1 16079642 937775 complement(2663929..2664408) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2664408 yqxI 937775 yqxI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390466.1 2663929 R 224308 CDS NP_390467.1 16079643 937772 complement(2664573..2665391) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1683402, 2127796; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase CwlA 2665391 cwlA 937772 cwlA Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase CwlA NP_390467.1 2664573 R 224308 CDS NP_390468.1 16079644 937782 complement(2665436..2665858) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2665858 yqxH 937782 yqxH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390468.1 2665436 R 224308 CDS NP_390469.1 16079645 937783 complement(2665903..2666796) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2666796 yqxG 937783 yqxG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390469.1 2665903 R 224308 CDS NP_390470.1 16079646 937759 complement(2666884..2667048) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2667048 yqcE 937759 yqcE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390470.1 2666884 R 224308 CDS NP_390471.1 16079647 937768 complement(2667045..2667380) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2667380 yqcD 937768 yqcD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390471.1 2667045 R 224308 CDS NP_390472.2 255767597 937773 complement(2667390..2668490) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein 2668490 yqcC 937773 yqcC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390472.2 2667390 R 224308 CDS NP_390473.1 16079649 937762 complement(2668493..2668765) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2668765 yqcB 937762 yqcB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390473.1 2668493 R 224308 CDS NP_390474.2 255767598 937763 complement(2668762..2669340) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein 2669340 yqcA 937763 yqcA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390474.2 2668762 R 224308 CDS NP_390475.1 16079651 937758 complement(2669324..2670370) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2670370 yqbT 937758 yqbT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390475.1 2669324 R 224308 CDS NP_390476.1 16079652 937757 complement(2670363..2670788) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2670788 yqbS 937757 yqbS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390476.1 2670363 R 224308 CDS NP_390477.1 16079653 937750 complement(2670801..2671064) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2671064 yqbR 937750 yqbR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390477.1 2670801 R 224308 CDS NP_390478.1 16079654 937751 complement(2671061..2672041) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2672041 yqbQ 937751 yqbQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390478.1 2671061 R 224308 CDS NP_390479.1 16079655 937756 complement(2672054..2672713) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2672713 yqbP 937756 yqbP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390479.1 2672054 R 224308 CDS NP_390480.2 255767599 937747 complement(2672706..2677463) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8760915, 8969508; Product type pe: enzyme; hypothetical protein 2677463 yqbO 937747 yqbO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390480.2 2672706 R 224308 CDS NP_390482.1 16079658 8303122 2678240..2678419 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2678419 yqdB 8303122 yqdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390482.1 2678240 D 224308 CDS NP_390483.2 255767600 937740 complement(2679142..2679585) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8760915, 8969508; hypothetical protein 2679585 yqbM 937740 yqbM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390483.2 2679142 R 224308 CDS NP_390485.2 255767601 937738 complement(2679588..2680988) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2680988 yqbK 937738 yqbK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390485.2 2679588 R 224308 CDS YP_003097763.1 255767602 8303132 complement(2680989..2681180) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2681180 yqzN 8303132 yqzN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097763.1 2680989 R 224308 CDS NP_390486.2 255767603 937746 complement(2681177..2681614) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2681614 yqbJ 937746 yqbJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390486.2 2681177 R 224308 CDS NP_390487.1 16079663 937737 complement(2681627..2682130) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2682130 yqbI 937737 yqbI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390487.1 2681627 R 224308 CDS NP_390488.1 16079664 937727 complement(2682127..2682489) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2682489 yqbH 937727 yqbH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390488.1 2682127 R 224308 CDS NP_390489.2 255767604 937739 complement(2682486..2682881) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2682881 yqbG 937739 yqbG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390489.2 2682486 R 224308 CDS NP_390490.1 16079666 937735 complement(2682885..2683196) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2683196 yqbF 937735 yqbF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390490.1 2682885 R 224308 CDS NP_390491.2 255767605 937722 complement(2683207..2684142) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2684142 yqbE 937722 yqbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390491.2 2683207 R 224308 CDS NP_390492.2 255767606 937736 complement(2684161..2685129) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2685129 yqbD 937736 yqbD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390492.2 2684161 R 224308 CDS NP_390493.1 16079669 937712 complement(2685162..2685815) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2685815 yqbC 937712 yqbC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390493.1 2685162 R 224308 CDS NP_390494.1 16079670 937723 complement(2685856..2686773) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2686773 yqbB 937723 yqbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390494.1 2685856 R 224308 CDS NP_390495.1 16079671 937707 complement(2686770..2688302) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2688302 yqbA 937707 yqbA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390495.1 2686770 R 224308 CDS NP_390496.1 16079672 937721 complement(2688306..2689601) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2689601 yqaT 937721 yqaT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390496.1 2688306 R 224308 CDS NP_390497.1 16079673 937704 complement(2689594..2690313) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2690313 yqaS 937704 yqaS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390497.1 2689594 R 224308 CDS NP_390498.1 16079674 937703 complement(2690381..2690845) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2690845 yqaR 937703 yqaR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390498.1 2690381 R 224308 CDS NP_390499.1 16079675 937693 complement(2690989..2691444) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2691444 yqaQ 937693 yqaQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390499.1 2690989 R 224308 CDS NP_390500.1 16079676 937705 2691642..2692571 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2692571 yqaP 937705 yqaP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390500.1 2691642 D 224308 CDS NP_390501.1 16079677 937706 complement(2692645..2692851) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2692851 yqaO 937706 yqaO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390501.1 2692645 R 224308 CDS NP_390502.1 16079678 937694 complement(2692933..2693361) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2693361 yqaN 937694 yqaN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390502.1 2692933 R 224308 CDS YP_003097764.1 255767607 8302984 complement(2693457..2693606) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2693606 yqzO 8302984 yqzO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097764.1 2693457 R 224308 CDS NP_390503.2 255767608 937685 complement(2693597..2694457) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2694457 yqaM 937685 yqaM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390503.2 2693597 R 224308 CDS NP_390504.2 255767609 937695 complement(2694420..2695097) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; DNA-binding protein 2695097 yqaL 937695 yqaL Bacillus subtilis subsp. subtilis str. 168 DNA-binding protein NP_390504.2 2694420 R 224308 CDS NP_390505.1 16079681 937691 complement(2695173..2696027) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2696027 yqaK 937691 yqaK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390505.1 2695173 R 224308 CDS NP_390506.1 16079682 937681 complement(2696030..2696989) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2696989 yqaJ 937681 yqaJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390506.1 2696030 R 224308 CDS NP_390507.1 16079683 937680 complement(2697095..2697289) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2697289 yqaI 937680 yqaI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390507.1 2697095 R 224308 CDS NP_390508.1 16079684 937692 complement(2697419..2697676) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2697676 yqaH 937692 yqaH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390508.1 2697419 R 224308 CDS NP_390509.1 16079685 937671 complement(2697673..2698242) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator 2698242 yqaG 937671 yqaG Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_390509.1 2697673 R 224308 CDS NP_390510.1 16079686 937682 complement(2698316..2698456) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2698456 yqdA 937682 yqdA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390510.1 2698316 R 224308 CDS NP_390511.1 16079687 937684 complement(2698486..2698716) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2698716 yqaF 937684 yqaF Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_390511.1 2698486 R 224308 CDS NP_390512.1 16079688 937672 2698893..2699243 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; XRE family transcriptional regulator 2699243 yqaE 937672 yqaE Bacillus subtilis subsp. subtilis str. 168 XRE family transcriptional regulator NP_390512.1 2698893 D 224308 CDS NP_390513.1 16079689 937674 complement(2699510..2699677) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2699677 yqaD 937674 yqaD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390513.1 2699510 R 224308 CDS NP_390514.1 16079690 937669 complement(2700033..2700569) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2700569 yqaC 937669 yqaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390514.1 2700033 R 224308 CDS NP_390515.1 16079691 937668 2700838..2701356 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2701356 yqaB 937668 yqaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390515.1 2700838 D 224308 CDS NP_390517.1 16079693 937670 complement(2701979..2702143) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2702143 yrkS 937670 yrkS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390517.1 2701979 R 224308 CDS NP_390518.2 255767610 937665 complement(2702688..2703104) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12897016, 15849754, 16850406; Product type m : membrane component; phosphate-starvation-inducible protein PsiE 2703104 yrkR 937665 yrkR Bacillus subtilis subsp. subtilis str. 168 phosphate-starvation-inducible protein PsiE NP_390518.2 2702688 R 224308 CDS NP_390519.1 16079695 937662 complement(2703150..2704448) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 2704448 yrkQ 937662 yrkQ Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_390519.1 2703150 R 224308 CDS NP_390520.1 16079696 937663 complement(2704435..2705130) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 18175906; Product type r: regulator; transcriptional regulator 2705130 yrkP 937663 yrkP Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_390520.1 2704435 R 224308 CDS NP_390521.1 16079697 937667 2705398..2706615 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2706615 yrkO 937667 yrkO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390521.1 2705398 D 224308 CDS NP_390522.1 16079698 937664 2707127..2707684 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2707684 yrkN 937664 yrkN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390522.1 2707127 D 224308 CDS NP_390524.2 255767611 937658 complement(2708175..2708699) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053405; Product type pe : enzyme; NAD(P)H oxidoreductase YrkL 2708699 yrkL 937658 yrkL Bacillus subtilis subsp. subtilis str. 168 NAD(P)H oxidoreductase YrkL NP_390524.2 2708175 R 224308 CDS NP_390525.2 255767612 937659 complement(2708943..2709419) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2709419 yrkK 937659 yrkK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390525.2 2708943 R 224308 CDS NP_390526.1 16079702 937654 complement(2710002..2710787) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2710787 yrkJ 937654 yrkJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390526.1 2710002 R 224308 CDS NP_390527.1 16079703 937657 complement(2710848..2711075) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2711075 yrkI 937657 yrkI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390527.1 2710848 R 224308 CDS NP_390528.2 255767613 937656 complement(2711109..2712242) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2712242 yrkH 937656 yrkH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390528.2 2711109 R 224308 CDS NP_390530.1 16079706 937647 complement(2712577..2713134) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2713134 yrkF 937647 yrkF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390530.1 2712577 R 224308 CDS NP_390531.1 16079707 937651 complement(2713320..2713802) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2713802 yrkE 937651 yrkE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390531.1 2713320 R 224308 CDS NP_390532.1 16079708 937650 complement(2713949..2714140) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2714140 yrkD 937650 yrkD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390532.1 2713949 R 224308 CDS NP_390533.1 16079709 937645 complement(2714933..2715493) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478; Product type pe : enzyme; hypothetical protein 2715493 yrkC 937645 yrkC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390533.1 2714933 R 224308 CDS NP_390534.1 16079710 937648 complement(2715719..2715865) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2715865 yrkB 937648 yrkB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390534.1 2715719 R 224308 CDS NP_390535.1 16079711 937644 complement(2716035..2716856) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 7608059, 9083003; Product type r: regulator; multidrug-efflux transporter 2 regulator 2716856 bltR 937644 bltR Bacillus subtilis subsp. subtilis str. 168 multidrug-efflux transporter 2 regulator NP_390535.1 2716035 R 224308 CDS NP_390536.1 16079712 937646 2716973..2718175 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 15849754, 16850406, 9083003; Product type t : transporter; multidrug resistance protein 2 2718175 blt 937646 blt Bacillus subtilis subsp. subtilis str. 168 multidrug resistance protein 2 NP_390536.1 2716973 D 224308 CDS NP_390537.1 16079713 937632 2718344..2718802 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 10359661, 12793527, 9083003; Product type e: enzyme; spermine/spermidine acetyltransferase 2718802 bltD 937632 bltD Bacillus subtilis subsp. subtilis str. 168 spermine/spermidine acetyltransferase NP_390537.1 2718344 D 224308 CDS NP_390538.1 16079714 937634 complement(2718959..2720263) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 2720263 yrkA 937634 yrkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390538.1 2718959 R 224308 CDS YP_003097765.1 255767614 8303041 complement(2720526..2720669) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2720669 yrzO 8303041 yrzO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097765.1 2720526 R 224308 CDS NP_390539.1 16079715 937629 complement(2720687..2721652) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 2721652 yrdR 937629 yrdR Bacillus subtilis subsp. subtilis str. 168 transporter NP_390539.1 2720687 R 224308 CDS NP_390540.1 16079716 937628 2721778..2722644 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator 2722644 yrdQ 937628 yrdQ Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_390540.1 2721778 D 224308 CDS NP_390541.1 16079717 937340 complement(2722767..2723804) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12100555, 12527699, 9099864; Product type pe: enzyme; oxidoreductase 2723804 yrdP 937340 yrdP Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390541.1 2722767 R 224308 CDS NP_390542.1 16079718 937630 complement(2723892..2724827) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735849, 12100555, 15849754, 15948947, 16850406; Product type t : transporter; cadmium, cobalt and zinc/H 2724827 czcD 937630 czcD Bacillus subtilis subsp. subtilis str. 168 cadmium, cobalt and zinc/H NP_390542.1 2723892 R 224308 CDS NP_390543.1 16079719 937627 complement(2725114..2725503) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YrdN 2725503 yrdN 937627 yrdN Bacillus subtilis subsp. subtilis str. 168 tautomerase YrdN NP_390543.1 2725114 R 224308 CDS NP_390544.2 255767615 938189 2725837..2726727 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9023181; Product type r : regulator; LysR family transcriptional regulator 2726727 gltR 938189 gltR Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_390544.2 2725837 D 224308 CDS NP_390545.2 255767616 938740 complement(2726885..2727163) 1 NC_000964.3 Evidence 6: Doubtful CDS; hypothetical protein 2727163 yrdK 938740 yrdK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390545.2 2726885 R 224308 CDS NP_390546.1 16079722 936930 complement(2727160..2728482) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 8544834, 9287000, 9531631; Product type t: transporter; branched-chain amino acid transport system carrier protein BrnQ 2728482 brnQ 936930 brnQ Bacillus subtilis subsp. subtilis str. 168 branched-chain amino acid transport system carrier protein BrnQ NP_390546.1 2727160 R 224308 CDS NP_390547.1 16079723 937624 complement(2728647..2728979) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type pt: transporter; branched-chain amino acid transport protein AzlD 2728979 azlD 937624 azlD Bacillus subtilis subsp. subtilis str. 168 branched-chain amino acid transport protein AzlD NP_390547.1 2728647 R 224308 CDS NP_390548.1 16079724 936606 complement(2728976..2729740) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 9287000; Product type t: transporter; branched-chain amino acid transport protein AzlC 2729740 azlC 936606 azlC Bacillus subtilis subsp. subtilis str. 168 branched-chain amino acid transport protein AzlC NP_390548.1 2728976 R 224308 CDS NP_390549.1 16079725 937625 complement(2729753..2730226) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9287000; Product type r : regulator; transcriptional regulator AzlB 2730226 azlB 937625 azlB Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator AzlB NP_390549.1 2729753 R 224308 CDS NP_390550.1 16079726 936691 complement(2730560..2730835) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; ribonuclease inhibitor YrdF 2730835 yrdF 936691 yrdF Bacillus subtilis subsp. subtilis str. 168 ribonuclease inhibitor YrdF NP_390550.1 2730560 R 224308 CDS NP_390551.1 16079727 937623 complement(2731107..2732339) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 9778370; Product type e: enzyme; cytochrome P450 2732339 cypA 937623 cypA Bacillus subtilis subsp. subtilis str. 168 cytochrome P450 NP_390551.1 2731107 R 224308 CDS NP_390553.1 16079729 937618 complement(2732980..2733543) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase 2733543 yrdC 937618 yrdC Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_390553.1 2732980 R 224308 CDS NP_390554.1 16079730 936140 complement(2733772..2734143) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2734143 yrdB 936140 yrdB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390554.1 2733772 R 224308 CDS NP_390555.1 16079731 937620 complement(2734953..2735456) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2735456 yrdA 937620 yrdA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390555.1 2734953 R 224308 CDS NP_390556.1 16079732 938061 complement(2735682..2736536) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8293959; Product type e : enzyme; aminoglycoside 6-adenylyltransferase 2736536 aadK 938061 aadK Bacillus subtilis subsp. subtilis str. 168 aminoglycoside 6-adenylyltransferase NP_390556.1 2735682 R 224308 CDS NP_390557.1 16079733 936455 2736915..2737958 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9501443; Product type pe : enzyme; nitronate monooxygenase 2737958 yrpB 936455 yrpB Bacillus subtilis subsp. subtilis str. 168 nitronate monooxygenase NP_390557.1 2736915 D 224308 CDS NP_390558.1 16079734 937619 2738308..2739105 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15347750; Product type e: enzyme; glutamate racemase 2739105 yrpC 937619 yrpC Bacillus subtilis subsp. subtilis str. 168 glutamate racemase NP_390558.1 2738308 D 224308 CDS NP_390559.1 16079735 937397 2739486..2740193 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 2740193 yrpD 937397 yrpD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390559.1 2739486 D 224308 CDS NP_390560.1 16079736 936254 complement(2741357..2742112) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; zinc-binding protein 2742112 yrpE 936254 yrpE Bacillus subtilis subsp. subtilis str. 168 zinc-binding protein NP_390560.1 2741357 R 224308 CDS NP_390561.1 16079737 937617 complement(2742244..2742774) 1 NC_000964.3 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigZ 2742774 sigZ 937617 sigZ Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigZ NP_390561.1 2742244 R 224308 CDS NP_390562.2 255767617 937611 2742909..2743889 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2743889 yrpG 937611 yrpG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390562.2 2742909 D 224308 CDS NP_390563.1 16079739 937610 complement(2744163..2745479) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11053381, 15849754, 16850406; Product type pt: transporter; transporter 2745479 yraO 937610 yraO Bacillus subtilis subsp. subtilis str. 168 transporter NP_390563.1 2744163 R 224308 CDS NP_390564.1 16079740 937614 complement(2745594..2746463) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; LysR family transcriptional regulator 2746463 yraN 937614 yraN Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_390564.1 2745594 R 224308 CDS NP_390565.2 255767618 936343 2746608..2747711 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; isomerase 2747711 yraM 936343 yraM Bacillus subtilis subsp. subtilis str. 168 isomerase NP_390565.2 2746608 D 224308 CDS NP_390566.1 16079742 936802 complement(2747984..2748817) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065371, 11320136, 1664582; Product type e: enzyme; chitosanase 2748817 csn 936802 csn Bacillus subtilis subsp. subtilis str. 168 chitosanase NP_390566.1 2747984 R 224308 CDS NP_390567.1 16079743 937608 2749260..2749523 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2749523 yraL 937608 yraL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390567.1 2749260 D 224308 CDS NP_390568.2 255767619 936746 2749660..2750475 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YraK 2750475 yraK 936746 yraK Bacillus subtilis subsp. subtilis str. 168 hydrolase YraK NP_390568.2 2749660 D 224308 CDS NP_390569.2 255767620 937609 complement(2750883..2751239) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2751239 yraJ 937609 yraJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390569.2 2750883 R 224308 CDS NP_390570.1 16079746 936030 complement(2751292..2751726) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2751726 yraI 936030 yraI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390570.1 2751292 R 224308 CDS NP_390571.1 16079747 937607 complement(2752167..2752553) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 2752553 yraH 937607 yraH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390571.1 2752167 R 224308 CDS NP_390572.1 16079748 936783 2752802..2753047 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2753047 yraG 936783 yraG Bacillus subtilis subsp. subtilis str. 168 spore coat protein F NP_390572.1 2752802 D 224308 CDS NP_390573.1 16079749 937606 2753065..2753433 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2753433 yraF 937606 yraF Bacillus subtilis subsp. subtilis str. 168 spore coat protein F NP_390573.1 2753065 D 224308 CDS NP_390574.2 255767621 937604 2753452..2754588 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 7926692; Product type pe : enzyme; zinc-type alcohol dehydrogenase 2754588 adhB 937604 adhB Bacillus subtilis subsp. subtilis str. 168 zinc-type alcohol dehydrogenase NP_390574.2 2753452 D 224308 CDS NP_390575.1 16079751 938108 2754607..2754804 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2754804 yraE 938108 yraE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390575.1 2754607 D 224308 CDS NP_390576.1 16079752 935919 2754820..2755119 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10066829; Product type cp : cell process; spore coat protein F 2755119 yraD 935919 yraD Bacillus subtilis subsp. subtilis str. 168 spore coat protein F NP_390576.1 2754820 D 224308 CDS NP_390578.2 255767622 937605 complement(2755382..2755804) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator; MerR family transcriptional regulator 2755804 yraB 937605 yraB Bacillus subtilis subsp. subtilis str. 168 MerR family transcriptional regulator NP_390578.2 2755382 R 224308 CDS NP_390579.2 255767623 938739 2756312..2757361 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; formaldehyde dehydrogenase AdhA 2757361 adhA 938739 adhA Bacillus subtilis subsp. subtilis str. 168 formaldehyde dehydrogenase AdhA NP_390579.2 2756312 D 224308 CDS NP_390580.2 50812271 937603 2757492..2758001 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12775685, 17257049, 17933887; Product type f: factor; cysteine protease YraA 2758001 yraA 937603 yraA Bacillus subtilis subsp. subtilis str. 168 cysteine protease YraA NP_390580.2 2757492 D 224308 CDS NP_390581.1 16079757 938092 complement(2758043..2760076) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7646030, 8057358; Product type e: enzyme; levanase 2760076 sacC 938092 sacC Bacillus subtilis subsp. subtilis str. 168 levanase NP_390581.1 2758043 R 224308 CDS NP_390582.1 16079758 937595 complement(2760233..2761060) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IID 2761060 levG 937595 levG Bacillus subtilis subsp. subtilis str. 168 PTS system fructose transporter subunit IID NP_390582.1 2760233 R 224308 CDS NP_390583.1 16079759 937602 complement(2761081..2761890) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IIC 2761890 levF 937602 levF Bacillus subtilis subsp. subtilis str. 168 PTS system fructose transporter subunit IIC NP_390583.1 2761081 R 224308 CDS NP_390584.1 16079760 937078 complement(2761907..2762395) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10589728, 9033408, 9622354; Product type t: transporter; PTS system fructose-specific transporter subunit IIB 2762395 levE 937078 levE Bacillus subtilis subsp. subtilis str. 168 PTS system fructose-specific transporter subunit IIB NP_390584.1 2761907 R 224308 CDS NP_390585.1 16079761 936536 complement(2762395..2762835) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 2117666, 9033408; Product type t: transporter; PTS system fructose transporter subunit IIA 2762835 levD 936536 levD Bacillus subtilis subsp. subtilis str. 168 PTS system fructose transporter subunit IIA NP_390585.1 2762395 R 224308 CDS NP_390586.2 255767624 937594 complement(2763025..2765832) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1619665, 1900939, 7592487, 8057358, 9622354; Product type r: regulator; transcriptional regulatory protein LevR 2765832 levR 937594 levR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein LevR NP_390586.2 2763025 R 224308 CDS NP_390587.2 255767625 937231 2766558..2767946 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406; Product type t : transporter; amino acid permease AapA 2767946 aapA 937231 aapA Bacillus subtilis subsp. subtilis str. 168 amino acid permease AapA NP_390587.2 2766558 D 224308 CDS NP_390588.1 16079764 937592 complement(2768042..2768674) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; membrane protein 2768674 yrhP 937592 yrhP Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390588.1 2768042 R 224308 CDS NP_390589.1 16079765 937224 2768827..2769654 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2769654 yrhO 937224 yrhO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390589.1 2768827 D 224308 CDS NP_390590.1 16079766 937591 2769850..2770350 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator; RNA polymerase sigma factor SigV 2770350 sigV 937591 sigV Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigV NP_390590.1 2769850 D 224308 CDS NP_390591.1 16079767 937593 2770350..2771207 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16274938; Product type r: regulator; anti-sigma-V factor RsiV 2771207 rsiV 937593 rsiV Bacillus subtilis subsp. subtilis str. 168 anti-sigma-V factor RsiV NP_390591.1 2770350 D 224308 CDS NP_390592.1 16079768 936583 2771318..2773222 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15661003; Product type e: enzyme; peptidoglycan O-acetyltransferase YrhL 2773222 oatA 936583 oatA Bacillus subtilis subsp. subtilis str. 168 peptidoglycan O-acetyltransferase YrhL NP_390592.1 2771318 D 224308 CDS NP_390593.1 16079769 937587 2773356..2773646 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2773646 yrhK 937587 yrhK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390593.1 2773356 D 224308 CDS NP_390594.1 16079770 937585 complement(2773890..2777054) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type e: enzyme; bifunctional P-450/NADPH-P450 reductase 2 2777054 cypB 937585 cypB Bacillus subtilis subsp. subtilis str. 168 bifunctional P-450/NADPH-P450 reductase 2 NP_390594.1 2773890 R 224308 CDS NP_390595.1 16079771 938491 complement(2777070..2777654) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11574077; Product type r: regulator; TetR family transcriptional regulator 2777654 bscR 938491 bscR Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_390595.1 2777070 R 224308 CDS NP_390596.1 16079772 938507 complement(2777877..2778419) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15870467; Product type pe : enzyme; methyltransferase 2778419 yrhH 938507 yrhH Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_390596.1 2777877 R 224308 CDS NP_390597.1 16079773 937584 complement(2778923..2779072) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2779072 yrzI 937584 yrzI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390597.1 2778923 R 224308 CDS NP_390598.1 16079774 937992 complement(2779462..2780262) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 2780262 yrhG 937992 yrhG Bacillus subtilis subsp. subtilis str. 168 transporter NP_390598.1 2779462 R 224308 CDS NP_390599.1 16079775 936371 complement(2780525..2780893) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2780893 yrhF 936371 yrhF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390599.1 2780525 R 224308 CDS NP_390600.1 16079776 937569 2781209..2784151 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913079; Product type pe : enzyme; formate dehydrogenase YrhE 2784151 yrhE 937569 yrhE Bacillus subtilis subsp. subtilis str. 168 formate dehydrogenase YrhE NP_390600.1 2781209 D 224308 CDS NP_390601.1 16079777 937583 2784170..2784652 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10913079; hypothetical protein 2784652 yrhD 937583 yrhD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390601.1 2784170 D 224308 CDS NP_390602.1 16079778 936495 complement(2784688..2784918) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751; hypothetical protein 2784918 yrhC 936495 yrhC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390602.1 2784688 R 224308 CDS NP_390603.1 16079779 936947 complement(2785001..2786140) 1 NC_000964.3 catalyzes the formation of L-homocysteine from cystathionine; cystathionine gamma-lyase 2786140 yrhB 936947 yrhB Bacillus subtilis subsp. subtilis str. 168 cystathionine gamma-lyase NP_390603.1 2785001 R 224308 CDS NP_390604.1 16079780 937576 complement(2786142..2787065) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 17056751; Product type e: enzyme; O-acetylserine dependent cystathionine beta-synthase 2787065 mccA 937576 mccA Bacillus subtilis subsp. subtilis str. 168 O-acetylserine dependent cystathionine beta-synthase NP_390604.1 2786142 R 224308 CDS NP_390605.1 16079781 938153 complement(2787130..2787825) 1 NC_000964.3 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase 2787825 mtn 938153 mtn Bacillus subtilis subsp. subtilis str. 168 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase NP_390605.1 2787130 R 224308 CDS NP_390606.1 16079782 937566 complement(2787846..2788487) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 17056751; Product type pe: enzyme; methyltransferase 2788487 yrrT 937566 yrrT Bacillus subtilis subsp. subtilis str. 168 methyltransferase NP_390606.1 2787846 R 224308 CDS NP_390607.1 16079783 937564 2788680..2788883 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2788883 yrzA 937564 yrzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390607.1 2788680 D 224308 CDS NP_390608.1 16079784 936614 complement(2788920..2789621) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14679248; membrane protein 2789621 yrrS 936614 yrrS Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390608.1 2788920 R 224308 CDS NP_390609.1 16079785 936016 complement(2789686..2791440) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14679248; Product type e: enzyme; penicillin-binding protein 4B 2791440 pbpI 936016 pbpI Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 4B NP_390609.1 2789686 R 224308 CDS NP_390610.1 16079786 937565 complement(2791494..2791967) 1 NC_000964.3 necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA 2791967 greA 937565 greA Bacillus subtilis subsp. subtilis str. 168 transcription elongation factor GreA NP_390610.1 2791494 R 224308 CDS NP_390611.1 16079787 937560 complement(2792218..2792853) 1 NC_000964.3 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 2792853 udk 937560 udk Bacillus subtilis subsp. subtilis str. 168 uridine kinase NP_390611.1 2792218 R 224308 CDS NP_390612.1 16079788 937561 complement(2792860..2794128) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YrrO 2794128 yrrO 937561 yrrO Bacillus subtilis subsp. subtilis str. 168 protease YrrO NP_390612.1 2792860 R 224308 CDS NP_390613.1 16079789 937559 complement(2794147..2795076) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; protease YrrN 2795076 yrrN 937559 yrrN Bacillus subtilis subsp. subtilis str. 168 protease YrrN NP_390613.1 2794147 R 224308 CDS NP_390614.1 16079790 937719 complement(2795082..2795735) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; O-methyltransferase YrrM 2795735 yrrM 937719 yrrM Bacillus subtilis subsp. subtilis str. 168 O-methyltransferase YrrM NP_390614.1 2795082 R 224308 CDS NP_390615.1 16079791 936260 complement(2795887..2796969) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2796969 yrrL 936260 yrrL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390615.1 2795887 R 224308 CDS NP_390616.1 16079792 938000 complement(2797100..2797381) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2797381 yrzB 938000 yrzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390616.1 2797100 R 224308 CDS NP_390617.1 16079793 937357 complement(2797399..2797815) 1 NC_000964.3 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase 2797815 yrrK 937357 yrrK Bacillus subtilis subsp. subtilis str. 168 Holliday junction resolvase NP_390617.1 2797399 R 224308 CDS YP_054589.1 50812272 2914283 complement(2797823..2798089) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2798089 yrzL 2914283 yrzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_054589.1 2797823 R 224308 CDS NP_390618.1 16079794 939643 complement(2798174..2800810) 1 NC_000964.3 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanine--tRNA ligase 2800810 alaS 939643 alaS Bacillus subtilis subsp. subtilis str. 168 alanine--tRNA ligase NP_390618.1 2798174 R 224308 CDS NP_390619.1 16079795 937557 complement(2801141..2802202) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 2802202 yrrI 937557 yrrI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390619.1 2801141 R 224308 CDS NP_390620.1 16079796 937558 2802358..2803086 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type t: transporter; glutamine transport ATP-binding protein GlnQ 2803086 glnQ 937558 glnQ Bacillus subtilis subsp. subtilis str. 168 glutamine transport ATP-binding protein GlnQ NP_390620.1 2802358 D 224308 CDS NP_390621.1 16079797 938139 2803108..2803929 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1856180; Product type lp: lipoprotein; ABC transporter glutamine-binding protein GlnH 2803929 glnH 938139 glnH Bacillus subtilis subsp. subtilis str. 168 ABC transporter glutamine-binding protein GlnH NP_390621.1 2803108 D 224308 CDS NP_390622.1 16079798 935975 2803990..2804640 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter; glutamine ABC transporter permease protein GlnM 2804640 glnM 935975 glnM Bacillus subtilis subsp. subtilis str. 168 glutamine ABC transporter permease protein GlnM NP_390622.1 2803990 D 224308 CDS NP_390623.1 16079799 937556 2804657..2805313 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1856180; Product type t : transporter; glutamine ABC transporter permease protein GlnP 2805313 glnP 937556 glnP Bacillus subtilis subsp. subtilis str. 168 glutamine ABC transporter permease protein GlnP NP_390623.1 2804657 D 224308 CDS YP_003097766.1 255767626 8302994 complement(2805348..2805479) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2805479 yrzQ 8302994 yrzQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097766.1 2805348 R 224308 CDS YP_003097767.1 255767627 8302944 complement(2805501..2805692) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2805692 yrzR 8302944 yrzR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097767.1 2805501 R 224308 CDS NP_390624.1 16079800 937552 complement(2805704..2806228) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2806228 yrrD 937552 yrrD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390624.1 2805704 R 224308 CDS NP_390625.1 16079801 937553 complement(2806286..2808682) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11557815, 3537961; Product type pe: enzyme; hypothetical protein 2808682 yrrC 937553 yrrC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390625.1 2806286 R 224308 CDS NP_390626.1 16079802 938093 complement(2808707..2809327) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11777911, 12594026; Product type pf: factor; TPR repeat-containing protein YrrB 2809327 yrrB 938093 yrrB Bacillus subtilis subsp. subtilis str. 168 TPR repeat-containing protein YrrB NP_390626.1 2808707 R 224308 CDS NP_390627.3 255767628 938049 complement(2809413..2810528) 1 NC_000964.3 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 2810528 mnmA 938049 mnmA Bacillus subtilis subsp. subtilis str. 168 tRNA-specific 2-thiouridylase MnmA NP_390627.3 2809413 R 224308 CDS NP_390629.2 50812274 937550 complement(2810559..2811698) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 10930739, 12682299, 17064282, 7496536; Product type e: enzyme; cysteine desulfurase IscS 1 2811698 iscS 937550 iscS Bacillus subtilis subsp. subtilis str. 168 cysteine desulfurase IscS 1 NP_390629.2 2810559 R 224308 CDS NP_390630.2 255767629 936456 complement(2811717..2812133) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668000, 16109943, 16513748, 17056751, 18974048; Product type r: regulator; Rrf2 family transcriptional regulator 2812133 cymR 936456 cymR Bacillus subtilis subsp. subtilis str. 168 Rrf2 family transcriptional regulator NP_390630.2 2811717 R 224308 CDS NP_390631.1 16079807 937545 2812336..2813601 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ATPase 2813601 yrvN 937545 yrvN Bacillus subtilis subsp. subtilis str. 168 ATPase NP_390631.1 2812336 D 224308 CDS NP_390632.3 255767630 938590 complement(2813643..2814407) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177353; Product type pe : enzyme; hypothetical protein 2814407 yrvM 938590 yrvM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390632.3 2813643 R 224308 CDS NP_390633.1 16079809 937549 complement(2814743..2816521) 1 NC_000964.3 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartate--tRNA ligase 2816521 aspS 937549 aspS Bacillus subtilis subsp. subtilis str. 168 aspartate--tRNA ligase NP_390633.1 2814743 R 224308 CDS NP_390634.1 16079810 938617 complement(2816535..2817809) 1 NC_000964.3 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidine--tRNA ligase 2817809 hisS 938617 hisS Bacillus subtilis subsp. subtilis str. 168 histidine--tRNA ligase NP_390634.1 2816535 R 224308 CDS NP_390635.1 16079811 936478 complement(2818191..2818361) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2818361 yrzK 936478 yrzK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390635.1 2818191 R 224308 CDS NP_390636.1 16079812 937544 2818494..2820050 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetylmuramoyl-L-alanine amidase YrvJ 2820050 yrvJ 937544 yrvJ Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase YrvJ NP_390636.1 2818494 D 224308 CDS NP_390637.2 50812276 936530 complement(2820077..2820475) 1 NC_000964.3 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase 2820475 yrvI 936530 yrvI Bacillus subtilis subsp. subtilis str. 168 D-tyrosyl-tRNA(Tyr) deacylase NP_390637.2 2820077 R 224308 CDS NP_390638.2 255767631 936753 complement(2820529..2822733) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11545276, 12081964, 13129942, 15066282, 6248722; Product type e: enzyme; GTP pyrophosphokinase 2822733 relA 936753 relA Bacillus subtilis subsp. subtilis str. 168 GTP pyrophosphokinase NP_390638.2 2820529 R 224308 CDS NP_390639.1 16079815 938063 complement(2822901..2823413) 1 NC_000964.3 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase 2823413 apt 938063 apt Bacillus subtilis subsp. subtilis str. 168 adenine phosphoribosyltransferase NP_390639.1 2822901 R 224308 CDS NP_390640.1 16079816 937538 complement(2823419..2825779) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; single-stranded-dna-specific exonuclease RecJ 2825779 recJ 937538 recJ Bacillus subtilis subsp. subtilis str. 168 single-stranded-dna-specific exonuclease RecJ NP_390640.1 2823419 R 224308 CDS NP_390641.1 16079817 937537 complement(2825846..2826169) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2826169 yrvD 937537 yrvD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390641.1 2825846 R 224308 CDS NP_390642.1 16079818 937539 complement(2826245..2826742) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14563871; Product type pt : transporter; hypothetical protein 2826742 yrvC 937539 yrvC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390642.1 2826245 R 224308 CDS NP_390643.1 16081162 937938 complement(2826900..2829113) 1 NC_000964.3 part of the preprotein secretory system; forms a complex with protein YajC; SecDFyajC stimulates the proton motive force-driven protein translocation, seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; protein translocase subunit SecDF 2829113 secDF 937938 secDF Bacillus subtilis subsp. subtilis str. 168 protein translocase subunit SecDF NP_390643.1 2826900 R 224308 CDS NP_390644.1 16079819 937536 complement(2829152..2829448) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 19028902; Product type r: regulator; post-transcriptional regulator 2829448 comN 937536 comN Bacillus subtilis subsp. subtilis str. 168 post-transcriptional regulator NP_390644.1 2829152 R 224308 CDS NP_390645.1 16079820 938022 2829564..2831120 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15292147, 15849754, 16850406, 1744050; Product type pt: transporter; stage V sporulation protein B 2831120 spoVB 938022 spoVB Bacillus subtilis subsp. subtilis str. 168 stage V sporulation protein B NP_390645.1 2829564 D 224308 CDS NP_390646.1 16079821 937535 complement(2831124..2831780) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2831780 yrbG 937535 yrbG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390646.1 2831124 R 224308 CDS NP_390647.1 16079822 938165 2831915..2832367 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2832367 yrzE 938165 yrzE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390647.1 2831915 D 224308 CDS NP_390648.2 255767632 936257 complement(2832424..2832690) 1 NC_000964.3 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC 2832690 yajC 936257 yajC Bacillus subtilis subsp. subtilis str. 168 preprotein translocase subunit YajC NP_390648.2 2832424 R 224308 CDS NP_390649.1 16079824 937528 complement(2832727..2833872) 1 NC_000964.3 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase 2833872 tgt 937528 tgt Bacillus subtilis subsp. subtilis str. 168 queuine tRNA-ribosyltransferase NP_390649.1 2832727 R 224308 CDS NP_390650.1 16079825 937975 complement(2833899..2834927) 1 NC_000964.3 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine:tRNA ribosyltransferase-isomerase 2834927 queA 937975 queA Bacillus subtilis subsp. subtilis str. 168 S-adenosylmethionine:tRNA ribosyltransferase-isomerase NP_390650.1 2833899 R 224308 CDS YP_003097768.1 255767633 8303137 complement(2834957..2835157) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2835157 yrzS 8303137 yrzS Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097768.1 2834957 R 224308 CDS YP_054590.1 50812277 2914219 complement(2835150..2836154) 1 NC_000964.3 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; holliday junction ATP-dependent DNA helicase RuvB 2836154 ruvB 2914219 ruvB Bacillus subtilis subsp. subtilis str. 168 holliday junction ATP-dependent DNA helicase RuvB YP_054590.1 2835150 R 224308 CDS NP_390652.1 16079826 937829 complement(2836165..2836770) 1 NC_000964.3 plays an essential role in ATP-dependent branch migration of the Holliday junction; holliday junction ATP-dependent DNA helicase RuvA 2836770 ruvA 937829 ruvA Bacillus subtilis subsp. subtilis str. 168 holliday junction ATP-dependent DNA helicase RuvA NP_390652.1 2836165 R 224308 CDS NP_390653.1 16079827 937526 complement(2836909..2837421) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931291, 16049010; Product type f: factor; general stress protein BofC 2837421 bofC 937526 bofC Bacillus subtilis subsp. subtilis str. 168 general stress protein BofC NP_390653.1 2836909 R 224308 CDS NP_390654.2 255767634 937527 complement(2837469..2838776) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9099855; Product type pt: transporter; alpha-ketoglutarate permease 2838776 csbX 937527 csbX Bacillus subtilis subsp. subtilis str. 168 alpha-ketoglutarate permease NP_390654.2 2837469 R 224308 CDS NP_390655.1 16079829 936523 complement(2838847..2839872) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2839872 yrbE 936523 yrbE Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390655.1 2838847 R 224308 CDS NP_390656.2 255767635 936570 2840110..2840757 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; serine/threonine protein kinase 2840757 yrzF 936570 yrzF Bacillus subtilis subsp. subtilis str. 168 serine/threonine protein kinase NP_390656.2 2840110 D 224308 CDS NP_390658.1 16079832 936007 2841169..2841300 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2841300 yrzH 936007 yrzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390658.1 2841169 D 224308 CDS YP_003097769.1 255767636 8303183 2841307..2841447 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 2841447 yrzT 8303183 yrzT Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097769.1 2841307 D 224308 CDS NP_390659.2 255767637 937941 2841611..2843065 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1400476, 15849754, 16850406; Product type t : transporter; sodium/proton-dependent alanine carrier protein YrbD 2843065 yrbD 937941 yrbD Bacillus subtilis subsp. subtilis str. 168 sodium/proton-dependent alanine carrier protein YrbD NP_390659.2 2841611 D 224308 CDS NP_390660.1 16079834 937517 complement(2843106..2843828) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; transcriptional regulator 2843828 yrbC 937517 yrbC Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_390660.1 2843106 R 224308 CDS NP_390661.2 255767638 937516 complement(2843931..2844527) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 9770294; Product type f: factor; sporulation cortex protein CoxA 2844527 coxA 937516 coxA Bacillus subtilis subsp. subtilis str. 168 sporulation cortex protein CoxA NP_390661.2 2843931 R 224308 CDS NP_390662.1 16079836 937514 complement(2844675..2845838) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438771, 10714986, 11040425, 15901704; Product type f: factor; spoivd-associated factor A 2845838 safA 937514 safA Bacillus subtilis subsp. subtilis str. 168 spoivd-associated factor A NP_390662.1 2844675 R 224308 CDS NP_390663.1 16079837 937522 complement(2845955..2847061) 1 NC_000964.3 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthase A 2847061 nadA 937522 nadA Bacillus subtilis subsp. subtilis str. 168 quinolinate synthase A NP_390663.1 2845955 R 224308 CDS NP_390664.1 16079838 936245 complement(2847048..2847917) 1 NC_000964.3 catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase 2847917 nadC 936245 nadC Bacillus subtilis subsp. subtilis str. 168 nicotinate-nucleotide pyrophosphorylase NP_390664.1 2847048 R 224308 CDS NP_390665.1 16079839 938051 complement(2847871..2849466) 1 NC_000964.3 catalyzes the formation of oxaloacetate from L-aspartate; L-aspartate oxidase 2849466 nadB 938051 nadB Bacillus subtilis subsp. subtilis str. 168 L-aspartate oxidase NP_390665.1 2847871 R 224308 CDS NP_390666.1 16079840 936637 2849569..2850756 1 NC_000964.3 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase NifS 2850756 nifS 936637 nifS Bacillus subtilis subsp. subtilis str. 168 cysteine desulfurase NifS NP_390666.1 2849569 D 224308 CDS NP_390667.2 255767639 937515 2850716..2851258 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16199587, 18276644; Product type r: regulator; transcription repressor NadR 2851258 nadR 937515 nadR Bacillus subtilis subsp. subtilis str. 168 transcription repressor NadR NP_390667.2 2850716 D 224308 CDS NP_390668.1 16079842 937513 complement(2851283..2852140) 1 NC_000964.3 catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase 2852140 pheA 937513 pheA Bacillus subtilis subsp. subtilis str. 168 prephenate dehydratase NP_390668.1 2851283 R 224308 CDS NP_390669.1 16079843 938171 complement(2852157..2852600) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 2537815; hypothetical protein 2852600 pheB 938171 pheB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390669.1 2852157 R 224308 CDS NP_390670.1 16079844 937502 complement(2852661..2853947) 1 NC_000964.3 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 2853947 obgE 937502 obgE Bacillus subtilis subsp. subtilis str. 168 GTPase ObgE NP_390670.1 2852661 R 224308 CDS NP_390671.1 16079845 935956 complement(2853981..2854559) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10997904, 9443976, 9477965, 9726997, 9809070; Product type e: enzyme; sporulation initiation phosphotransferase B 2854559 spo0B 935956 spo0B Bacillus subtilis subsp. subtilis str. 168 sporulation initiation phosphotransferase B NP_390671.1 2853981 R 224308 CDS NP_390672.1 16079846 937511 complement(2854880..2855164) 1 NC_000964.3 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 2855164 rpmA 937511 rpmA Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L27 NP_390672.1 2854880 R 224308 CDS NP_390673.2 255767640 937961 complement(2855177..2855515) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11567142; hypothetical protein 2855515 ysxB 937961 ysxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390673.2 2855177 R 224308 CDS NP_390674.1 16079848 936368 complement(2855518..2855826) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299; Product type f: factor; 50S ribosomal protein L21 2855826 rplU 936368 rplU Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L21 NP_390674.1 2855518 R 224308 CDS NP_390675.1 16079849 937505 complement(2855973..2856839) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type cp : cell process; stage IV sporulation protein FB 2856839 spoIVFB 937505 spoIVFB Bacillus subtilis subsp. subtilis str. 168 stage IV sporulation protein FB NP_390675.1 2855973 R 224308 CDS NP_390676.1 16079850 937501 complement(2856832..2857626) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809718, 11959848, 15087499, 16731018, 16816000, 16818230; Product type r : regulator; stage IV sporulation protein FA 2857626 spoIVFA 937501 spoIVFA Bacillus subtilis subsp. subtilis str. 168 stage IV sporulation protein FA NP_390676.1 2856832 R 224308 CDS NP_390677.1 16079851 937499 complement(2857776..2858582) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11886553, 12426398, 12492852, 12492861, 16322744, 16885474, 17513368; Product type cp: cell process; septum site-determining protein MinD 2858582 minD 937499 minD Bacillus subtilis subsp. subtilis str. 168 septum site-determining protein MinD NP_390677.1 2857776 R 224308 CDS NP_390678.1 16079852 937500 complement(2858584..2859264) 1 NC_000964.3 blocks the formation of polar Z-ring septums; septum site-determining protein MinC 2859264 minC 937500 minC Bacillus subtilis subsp. subtilis str. 168 septum site-determining protein MinC NP_390678.1 2858584 R 224308 CDS NP_390679.1 16079853 936183 complement(2859317..2859835) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16101995, 16850406; Product type s: structure; rod shape-determining protein MreD 2859835 mreD 936183 mreD Bacillus subtilis subsp. subtilis str. 168 rod shape-determining protein MreD NP_390679.1 2859317 R 224308 CDS NP_390680.2 255767641 937498 complement(2859832..2860704) 1 NC_000964.3 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; cell shape-determining protein MreC 2860704 mreC 937498 mreC Bacillus subtilis subsp. subtilis str. 168 cell shape-determining protein MreC NP_390680.2 2859832 R 224308 CDS NP_390681.2 255767642 936759 complement(2860735..2861748) 1 NC_000964.3 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 2861748 mreB 936759 mreB Bacillus subtilis subsp. subtilis str. 168 rod shape-determining protein MreB NP_390681.2 2860735 R 224308 CDS NP_390682.1 16079856 936544 complement(2861840..2862535) 1 NC_000964.3 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; hypothetical protein 2862535 radC 936544 radC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390682.1 2861840 R 224308 CDS NP_390683.1 16079857 936605 complement(2862572..2863141) 1 NC_000964.3 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; septum formation protein Maf 2863141 maf 936605 maf Bacillus subtilis subsp. subtilis str. 168 septum formation protein Maf NP_390683.1 2862572 R 224308 CDS NP_390684.1 16079858 937497 complement(2863294..2864292) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16959571, 17376078; Product type cp: cell process; stage II sporulation protein B 2864292 spoIIB 937497 spoIIB Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein B NP_390684.1 2863294 R 224308 CDS NP_390685.2 255767643 936586 complement(2864426..2865172) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16751195, 16850406, 2553669, 9723928; Product type cp: cell process; type 4 prepilin-like proteins leader peptide-processing enzyme 2865172 comC 936586 comC Bacillus subtilis subsp. subtilis str. 168 type 4 prepilin-like proteins leader peptide-processing enzyme NP_390685.2 2864426 R 224308 CDS NP_390686.1 16079860 936327 complement(2865312..2866604) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 2105929, 2985605, 3040739, 6994831, 9098041; Product type e: enzyme; folylpolyglutamate synthase 2866604 folC 936327 folC Bacillus subtilis subsp. subtilis str. 168 folylpolyglutamate synthase NP_390686.1 2865312 R 224308 CDS NP_390687.2 255767644 937491 complement(2866664..2869306) 1 NC_000964.3 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valine--tRNA ligase 2869306 valS 937491 valS Bacillus subtilis subsp. subtilis str. 168 valine--tRNA ligase NP_390687.2 2866664 R 224308 CDS YP_003097770.1 255767645 8302989 2869754..2869945 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2869945 yszA 8302989 yszA Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097770.1 2869754 D 224308 CDS NP_390688.1 16079862 937496 complement(2869964..2870989) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16371471, 16390444; Product type cp: cell process; hypothetical protein 2870989 ysxE 937496 ysxE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390688.1 2869964 R 224308 CDS NP_390689.1 16079863 936772 complement(2871022..2872749) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11325931, 16371471, 16950916; Product type cp: cell process; stage VI sporulation protein D 2872749 spoVID 936772 spoVID Bacillus subtilis subsp. subtilis str. 168 stage VI sporulation protein D NP_390689.1 2871022 R 224308 CDS NP_390690.1 16079864 937490 complement(2872880..2874172) 1 NC_000964.3 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; glutamate-1-semialdehyde 2,1-aminomutase 2874172 hemL 937490 hemL Bacillus subtilis subsp. subtilis str. 168 glutamate-1-semialdehyde 2,1-aminomutase NP_390690.1 2872880 R 224308 CDS NP_390691.1 16079865 936972 complement(2874202..2875176) 1 NC_000964.3 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 2875176 hemB 936972 hemB Bacillus subtilis subsp. subtilis str. 168 delta-aminolevulinic acid dehydratase NP_390691.1 2874202 R 224308 CDS NP_390692.1 16079866 937287 complement(2875173..2875961) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 15802251, 2110138; Product type e: enzyme; uroporphyrinogen-iii synthase 2875961 hemD 937287 hemD Bacillus subtilis subsp. subtilis str. 168 uroporphyrinogen-iii synthase NP_390692.1 2875173 R 224308 CDS NP_390693.1 16079867 937488 complement(2875951..2876895) 1 NC_000964.3 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 2876895 hemC 937488 hemC Bacillus subtilis subsp. subtilis str. 168 porphobilinogen deaminase NP_390693.1 2875951 R 224308 CDS NP_390694.2 255767646 937489 complement(2876928..2877758) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12029044, 15802251, 15849754, 16850406, 8012594; Product type f: factor; protein HemX 2877758 hemX 937489 hemX Bacillus subtilis subsp. subtilis str. 168 protein HemX NP_390694.2 2876928 R 224308 CDS NP_390695.1 16079869 937443 complement(2877766..2879133) 1 NC_000964.3 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins; glutamyl-tRNA reductase 2879133 hemA 937443 hemA Bacillus subtilis subsp. subtilis str. 168 glutamyl-tRNA reductase NP_390695.1 2877766 R 224308 CDS NP_390696.2 255767647 937352 2879363..2879860 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2879860 ysxD 937352 ysxD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390696.2 2879363 D 224308 CDS NP_390697.1 16079871 938009 complement(2879882..2880469) 1 NC_000964.3 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; GTP-binding protein EngB 2880469 engB 938009 engB Bacillus subtilis subsp. subtilis str. 168 GTP-binding protein EngB NP_390697.1 2879882 R 224308 CDS NP_390698.1 16079872 937486 complement(2880466..2882790) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926, 15987505; Product type e: enzyme; Lon protease 1 2882790 lonA 937486 lonA Bacillus subtilis subsp. subtilis str. 168 Lon protease 1 NP_390698.1 2880466 R 224308 CDS NP_390699.1 16079873 937484 complement(2882971..2884629) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10411757, 11325926; Product type e: enzyme; Lon protease 2 2884629 lonB 937484 lonB Bacillus subtilis subsp. subtilis str. 168 Lon protease 2 NP_390699.1 2882971 R 224308 CDS NP_390700.2 255767648 937482 complement(2884781..2886043) 1 NC_000964.3 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent Clp protease ATP-binding subunit ClpX 2886043 clpX 937482 clpX Bacillus subtilis subsp. subtilis str. 168 ATP-dependent Clp protease ATP-binding subunit ClpX NP_390700.2 2884781 R 224308 CDS NP_390701.1 16079875 936610 complement(2886315..2887589) 1 NC_000964.3 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 2887589 tig 936610 tig Bacillus subtilis subsp. subtilis str. 168 trigger factor NP_390701.1 2886315 R 224308 CDS NP_390702.2 255767649 937479 complement(2887817..2888821) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; TPR repeat-containing protein YsoA 2888821 ysoA 937479 ysoA Bacillus subtilis subsp. subtilis str. 168 TPR repeat-containing protein YsoA NP_390702.2 2887817 R 224308 CDS NP_390703.1 16079877 937683 complement(2888940..2889539) 1 NC_000964.3 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D; 3-isopropylmalate dehydratase small subunit 2889539 leuD 937683 leuD Bacillus subtilis subsp. subtilis str. 168 3-isopropylmalate dehydratase small subunit NP_390703.1 2888940 R 224308 CDS NP_390704.1 16079878 937478 complement(2889552..2890970) 1 NC_000964.3 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; 3-isopropylmalate dehydratase large subunit 2890970 leuC 937478 leuC Bacillus subtilis subsp. subtilis str. 168 3-isopropylmalate dehydratase large subunit NP_390704.1 2889552 R 224308 CDS NP_390705.2 255767650 936221 complement(2891020..2892117) 1 NC_000964.3 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 2892117 leuB 936221 leuB Bacillus subtilis subsp. subtilis str. 168 3-isopropylmalate dehydrogenase NP_390705.2 2891020 R 224308 CDS NP_390706.1 16079880 936316 complement(2892138..2893694) 1 NC_000964.3 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis; 2-isopropylmalate synthase 2893694 leuA 936316 leuA Bacillus subtilis subsp. subtilis str. 168 2-isopropylmalate synthase NP_390706.1 2892138 R 224308 CDS NP_390707.1 16079881 937475 complement(2893681..2894709) 1 NC_000964.3 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 2894709 ilvC 937475 ilvC Bacillus subtilis subsp. subtilis str. 168 ketol-acid reductoisomerase NP_390707.1 2893681 R 224308 CDS NP_390708.2 255767651 937477 complement(2894733..2895251) 1 NC_000964.3 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase small subunit 2895251 ilvH 937477 ilvH Bacillus subtilis subsp. subtilis str. 168 acetolactate synthase small subunit NP_390708.2 2894733 R 224308 CDS NP_390709.1 16079883 936792 complement(2895248..2896972) 1 NC_000964.3 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase large subunit 2896972 ilvB 936792 ilvB Bacillus subtilis subsp. subtilis str. 168 acetolactate synthase large subunit NP_390709.1 2895248 R 224308 CDS NP_390710.1 16079884 937466 2897788..2898123 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2898123 ysnD 937466 ysnD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390710.1 2897788 D 224308 CDS NP_390711.1 16079885 937464 2898292..2898747 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YsnE 2898747 ysnE 937464 ysnE Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YsnE NP_390711.1 2898292 D 224308 CDS NP_390712.3 255767652 936228 2898931..2899752 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type ph : phenotype; stress response protein YsnF 2899752 ysnF 936228 ysnF Bacillus subtilis subsp. subtilis str. 168 stress response protein YsnF NP_390712.3 2898931 D 224308 CDS NP_390713.2 255767653 938021 complement(2900020..2900529) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; Product type e: enzyme; metallophosphoesterase 2900529 ysnB 938021 ysnB Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_390713.2 2900020 R 224308 CDS NP_390714.1 16079888 937465 complement(2900545..2901141) 1 NC_000964.3 hydrolyzes non-standard nucleotides such as xanthine and inosine; non-canonical purine NTP pyrophosphatase 2901141 ysnA 937465 ysnA Bacillus subtilis subsp. subtilis str. 168 non-canonical purine NTP pyrophosphatase NP_390714.1 2900545 R 224308 CDS NP_390715.1 16079889 937463 complement(2901154..2901891) 1 NC_000964.3 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs; ribonuclease PH 2901891 rph 937463 rph Bacillus subtilis subsp. subtilis str. 168 ribonuclease PH NP_390715.1 2901154 R 224308 CDS NP_390716.1 16079890 936490 complement(2902002..2903102) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14662349; Product type cp: cell process; spore germination protein GerM 2903102 gerM 936490 gerM Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerM NP_390716.1 2902002 R 224308 CDS NP_390717.2 255767654 935934 complement(2903217..2904035) 1 NC_000964.3 converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase 2904035 racE 935934 racE Bacillus subtilis subsp. subtilis str. 168 glutamate racemase NP_390717.2 2903217 R 224308 CDS NP_390718.1 16079892 937461 complement(2904043..2904483) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; MarR family transcriptional regulator 2904483 ysmB 937461 ysmB Bacillus subtilis subsp. subtilis str. 168 MarR family transcriptional regulator NP_390718.1 2904043 R 224308 CDS NP_390719.2 255767655 937462 complement(2904727..2904951) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11243786, 11418558, 11741866, 14702409, 17172339; Product type cp: cell process; spore germination protein GerE 2904951 gerE 937462 gerE Bacillus subtilis subsp. subtilis str. 168 spore germination protein GerE NP_390719.2 2904727 R 224308 CDS NP_390720.1 16079894 937652 complement(2905067..2905510) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2905510 ysmA 937652 ysmA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390720.1 2905067 R 224308 CDS NP_390721.1 16079895 937460 complement(2905571..2906332) 1 NC_000964.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 2906332 sdhB 937460 sdhB Bacillus subtilis subsp. subtilis str. 168 succinate dehydrogenase iron-sulfur subunit NP_390721.1 2905571 R 224308 CDS NP_390722.2 255767656 937600 complement(2906335..2908095) 1 NC_000964.3 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 2908095 sdhA 937600 sdhA Bacillus subtilis subsp. subtilis str. 168 succinate dehydrogenase flavoprotein subunit NP_390722.2 2906335 R 224308 CDS NP_390723.1 16079897 937458 complement(2908129..2908737) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11803018, 15849754, 16850406, 1707123; Product type e: enzyme; succinate dehydrogenase cytochrome b558 subunit 2908737 sdhC 937458 sdhC Bacillus subtilis subsp. subtilis str. 168 succinate dehydrogenase cytochrome b558 subunit NP_390723.1 2908129 R 224308 CDS NP_390724.1 16079898 936806 2909030..2909476 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2909476 yslB 936806 yslB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390724.1 2909030 D 224308 CDS NP_390725.1 16079899 937451 complement(2909520..2910746) 1 NC_000964.3 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartokinase 2 2910746 lysC 937451 lysC Bacillus subtilis subsp. subtilis str. 168 aspartokinase 2 NP_390725.1 2909520 R 224308 CDS NP_390727.2 255767657 937729 complement(2911116..2912888) 1 NC_000964.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; UvrABC system protein C 2912888 uvrC 937729 uvrC Bacillus subtilis subsp. subtilis str. 168 UvrABC system protein C NP_390727.2 2911116 R 224308 CDS NP_390728.1 16079902 938187 complement(2913024..2913338) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15937154; Product type c: carrier; thioredoxin 2913338 trxA 938187 trxA Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_390728.1 2913024 R 224308 CDS NP_390729.2 255767658 937449 complement(2913661..2915148) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 14973026; Product type e: enzyme; alpha-L-arabinofuranosidase 2915148 xsa 937449 xsa Bacillus subtilis subsp. subtilis str. 168 alpha-L-arabinofuranosidase NP_390729.2 2913661 R 224308 CDS NP_390730.1 16079904 936520 complement(2915365..2916342) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; electron transfer flavoprotein subunit alpha 2916342 etfA 936520 etfA Bacillus subtilis subsp. subtilis str. 168 electron transfer flavoprotein subunit alpha NP_390730.1 2915365 R 224308 CDS NP_390731.1 16079905 937962 complement(2916378..2917151) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10026281, 17189250; Product type e: enzyme; electron transfer flavoprotein subunit beta 2917151 etfB 937962 etfB Bacillus subtilis subsp. subtilis str. 168 electron transfer flavoprotein subunit beta NP_390731.1 2916378 R 224308 CDS NP_390732.1 16079906 937448 complement(2917166..2917942) 1 NC_000964.3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 2917942 ysiB 937448 ysiB Bacillus subtilis subsp. subtilis str. 168 enoyl-CoA hydratase NP_390732.1 2917166 R 224308 CDS NP_390733.1 16079907 938105 complement(2917957..2918541) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type r: regulator; fatty acid metabolism regulator protein 2918541 fadR 938105 fadR Bacillus subtilis subsp. subtilis str. 168 fatty acid metabolism regulator protein NP_390733.1 2917957 R 224308 CDS NP_390734.1 16079908 936505 complement(2918646..2920328) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; long-chain-fatty-acid--CoA ligase 2920328 lcfA 936505 lcfA Bacillus subtilis subsp. subtilis str. 168 long-chain-fatty-acid--CoA ligase NP_390734.1 2918646 R 224308 CDS NP_390735.1 16079909 937969 complement(2920517..2920921) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2920921 yshE 937969 yshE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390735.1 2920517 R 224308 CDS NP_390736.1 16079910 937447 complement(2920936..2923293) 1 NC_000964.3 MutS2; MutS-II; involved in blocking homologous and homeologous recombination; has ATPase activity stimulated by recombination intermediates; inhibits DNA strand exchange; methyl-directed mismatch repair protein MutS 2923293 mutSB 937447 mutSB Bacillus subtilis subsp. subtilis str. 168 methyl-directed mismatch repair protein MutS NP_390736.1 2920936 R 224308 CDS NP_390737.1 16079911 937426 complement(2923314..2925026) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18938175; Product type e: enzyme; DNA polymerase/3'-5' exonuclease PolX 2925026 yshC 937426 yshC Bacillus subtilis subsp. subtilis str. 168 DNA polymerase/3'-5' exonuclease PolX NP_390737.1 2923314 R 224308 CDS NP_390738.1 16079912 937446 complement(2925100..2925633) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; transmembrane protein YshB 2925633 yshB 937446 yshB Bacillus subtilis subsp. subtilis str. 168 transmembrane protein YshB NP_390738.1 2925100 R 224308 CDS NP_390739.1 16079913 937442 complement(2925640..2925897) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; cell division protein ZapA 2925897 yshA 937442 yshA Bacillus subtilis subsp. subtilis str. 168 cell division protein ZapA NP_390739.1 2925640 R 224308 CDS NP_390740.1 16079914 937436 2926031..2926972 1 NC_000964.3 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII 2926972 rnhC 937436 rnhC Bacillus subtilis subsp. subtilis str. 168 ribonuclease HIII NP_390740.1 2926031 D 224308 CDS NP_390741.1 16079915 937445 complement(2927008..2929422) 1 NC_000964.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanine--tRNA ligase beta subunit 2929422 pheT 937445 pheT Bacillus subtilis subsp. subtilis str. 168 phenylalanine--tRNA ligase beta subunit NP_390741.1 2927008 R 224308 CDS NP_390742.1 16079916 937987 complement(2929438..2930472) 1 NC_000964.3 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanine--tRNA ligase alpha subunit 2930472 pheS 937987 pheS Bacillus subtilis subsp. subtilis str. 168 phenylalanine--tRNA ligase alpha subunit NP_390742.1 2929438 R 224308 CDS NP_390743.1 16079917 937444 complement(2930827..2931573) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tRNA/rRNA methyltransferase YsgA 2931573 ysgA 937444 ysgA Bacillus subtilis subsp. subtilis str. 168 tRNA/rRNA methyltransferase YsgA NP_390743.1 2930827 R 224308 CDS NP_390744.1 16079918 937579 2931692..2931907 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10806362, 8171126; Product type f: factor; small acid-soluble spore protein I 2931907 sspI 937579 sspI Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein I NP_390744.1 2931692 D 224308 CDS NP_390745.2 255767659 937437 2931976..2933082 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 2933082 ysfB 937437 ysfB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390745.2 2931976 D 224308 CDS NP_390746.1 16079920 937770 2933185..2934597 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8606183; Product type e: enzyme; glycolate oxidase subunit GlcD 2934597 glcD 937770 glcD Bacillus subtilis subsp. subtilis str. 168 glycolate oxidase subunit GlcD NP_390746.1 2933185 D 224308 CDS NP_390747.1 16079921 937435 2934594..2935928 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; glycolate oxidase iron-sulfur subunit 2935928 glcF 937435 glcF Bacillus subtilis subsp. subtilis str. 168 glycolate oxidase iron-sulfur subunit NP_390747.1 2934594 D 224308 CDS NP_390748.1 16079922 937588 complement(2935967..2936209) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 2936209 ysfE 937588 ysfE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390748.1 2935967 R 224308 CDS NP_390749.2 255767660 937970 complement(2936382..2938178) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16850406, 1848300; Product type ph : phenotype; carbon starvation protein A homolog 2938178 cstA 937970 cstA Bacillus subtilis subsp. subtilis str. 168 carbon starvation protein A homolog NP_390749.2 2936382 R 224308 CDS NP_390750.2 255767661 937509 complement(2938330..2939832) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 12777810, 14973026, 16233670; Product type e: enzyme; alpha-L-arabinofuranosidase 2939832 abfA 937509 abfA Bacillus subtilis subsp. subtilis str. 168 alpha-L-arabinofuranosidase NP_390750.2 2938330 R 224308 CDS NP_390751.2 255767662 937434 complement(2939851..2940696) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter; L-arabinose transport system permease protein AraQ 2940696 araQ 937434 araQ Bacillus subtilis subsp. subtilis str. 168 L-arabinose transport system permease protein AraQ NP_390751.2 2939851 R 224308 CDS NP_390752.1 16079926 937432 complement(2940697..2941638) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026, 15849754, 16850406; Product type t: transporter; L-arabinose transport system permease protein AraP 2941638 araP 937432 araP Bacillus subtilis subsp. subtilis str. 168 L-arabinose transport system permease protein AraP NP_390752.1 2940697 R 224308 CDS NP_390753.2 255767663 937433 complement(2941674..2942975) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10417639, 11418559, 14973026; Product type lp : lipoprotein; arabinose-binding protein 2942975 araN 937433 araN Bacillus subtilis subsp. subtilis str. 168 arabinose-binding protein NP_390753.2 2941674 R 224308 CDS NP_390754.1 16079928 938011 complement(2943006..2944190) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme; glycerol-1-phosphate dehydrogenase 2944190 araM 938011 araM Bacillus subtilis subsp. subtilis str. 168 glycerol-1-phosphate dehydrogenase NP_390754.1 2943006 R 224308 CDS NP_390755.1 16079929 937431 complement(2944187..2945005) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10417639, 11418559, 14973026; Product type pe: enzyme; arabinose operon protein AraL 2945005 araL 937431 araL Bacillus subtilis subsp. subtilis str. 168 arabinose operon protein AraL NP_390755.1 2944187 R 224308 CDS NP_390756.1 16079930 937894 complement(2944983..2945672) 1 NC_000964.3 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source; L-ribulose-5-phosphate 4-epimerase 2945672 araD 937894 araD Bacillus subtilis subsp. subtilis str. 168 L-ribulose-5-phosphate 4-epimerase NP_390756.1 2944983 R 224308 CDS NP_390757.1 16079931 936019 complement(2945689..2947371) 1 NC_000964.3 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate; ribulokinase 2947371 araB 936019 araB Bacillus subtilis subsp. subtilis str. 168 ribulokinase NP_390757.1 2945689 R 224308 CDS NP_390758.2 255767664 936764 complement(2947385..2948875) 1 NC_000964.3 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism; L-arabinose isomerase 2948875 araA 936764 araA Bacillus subtilis subsp. subtilis str. 168 L-arabinose isomerase NP_390758.2 2947385 R 224308 CDS NP_390759.2 255767665 937430 complement(2949053..2950024) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14973026; Product type e: enzyme; arabinan-endo 1,5-alpha-L-arabinase 2950024 abnA 937430 abnA Bacillus subtilis subsp. subtilis str. 168 arabinan-endo 1,5-alpha-L-arabinase NP_390759.2 2949053 R 224308 CDS NP_390760.1 16079934 936750 complement(2950221..2951306) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aminopeptidase 2951306 ysdC 936750 ysdC Bacillus subtilis subsp. subtilis str. 168 aminopeptidase NP_390760.1 2950221 R 224308 CDS NP_390761.1 16079935 937429 2951490..2951882 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10960106; sigma-W pathway protein YsdB 2951882 ysdB 937429 ysdB Bacillus subtilis subsp. subtilis str. 168 sigma-W pathway protein YsdB NP_390761.1 2951490 D 224308 CDS NP_390762.1 16079936 937419 complement(2951898..2952167) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 2952167 ysdA 937419 ysdA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390762.1 2951898 R 224308 CDS NP_390763.1 16079937 936645 complement(2952224..2952583) 1 NC_000964.3 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 2952583 rplT 936645 rplT Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L20 NP_390763.1 2952224 R 224308 CDS NP_390764.1 16079938 937421 complement(2952615..2952815) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17289755, 8722036; Product type s : structure; 50S ribosomal protein L35 2952815 rpmI 937421 rpmI Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L35 NP_390764.1 2952615 R 224308 CDS NP_390765.1 16079939 937835 complement(2952828..2953349) 1 NC_000964.3 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 2953349 infC 937835 infC Bacillus subtilis subsp. subtilis str. 168 translation initiation factor IF-3 NP_390765.1 2952828 R 224308 CDS NP_390767.2 255767666 936599 2953795..2954460 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15033535; Product type lp : lipoprotein; hypothetical protein 2954460 yscB 936599 yscB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390767.2 2953795 D 224308 CDS NP_390768.1 16079942 937418 complement(2954492..2955187) 1 NC_000964.3 in conjunction with LrgA this protein inhibits the expression or activity of extracellular murein hydrolases; antiholin-like protein LrgB 2955187 ysbB 937418 ysbB Bacillus subtilis subsp. subtilis str. 168 antiholin-like protein LrgB NP_390768.1 2954492 R 224308 CDS NP_390769.1 16079943 937417 complement(2955209..2955649) 1 NC_000964.3 negatively regulates murein hydrolase activity; antiholin-like protein LrgA 2955649 ysbA 937417 ysbA Bacillus subtilis subsp. subtilis str. 168 antiholin-like protein LrgA NP_390769.1 2955209 R 224308 CDS NP_390770.1 16079944 936931 complement(2955783..2956508) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12034833, 12914674; Product type r: regulator; sensory transduction protein LytT 2956508 lytT 936931 lytT Bacillus subtilis subsp. subtilis str. 168 sensory transduction protein LytT NP_390770.1 2955783 R 224308 CDS NP_390771.1 16079945 937404 complement(2956486..2958267) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10940023, 11717295, 12914674; Product type rc : receptor; sensor protein LytS 2958267 lytS 937404 lytS Bacillus subtilis subsp. subtilis str. 168 sensor protein LytS NP_390771.1 2956486 R 224308 CDS NP_390772.2 255767667 936546 2958434..2959216 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YsaA 2959216 ysaA 936546 ysaA Bacillus subtilis subsp. subtilis str. 168 hydrolase YsaA NP_390772.2 2958434 D 224308 CDS NP_390773.1 16079947 937410 complement(2959257..2961188) 1 NC_000964.3 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonine--tRNA ligase 1 2961188 thrS 937410 thrS Bacillus subtilis subsp. subtilis str. 168 threonine--tRNA ligase 1 NP_390773.1 2959257 R 224308 CDS NP_390774.2 255767668 937401 complement(2961586..2962431) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2962431 ytxC 937401 ytxC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390774.2 2961586 R 224308 CDS NP_390775.1 16079949 937403 complement(2962510..2963151) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; tvp38/tmem64 family membrane protein YtxB 2963151 ytxB 937403 ytxB Bacillus subtilis subsp. subtilis str. 168 tvp38/tmem64 family membrane protein YtxB NP_390775.1 2962510 R 224308 CDS NP_390776.1 16079950 936873 complement(2963185..2964120) 1 NC_000964.3 Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI 2964120 dnaI 936873 dnaI Bacillus subtilis subsp. subtilis str. 168 primosomal protein DnaI NP_390776.1 2963185 R 224308 CDS NP_390777.1 16079951 937396 complement(2964148..2965566) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 15186423, 16002087, 17289076; Product type f: factor; replication initiation and membrane attachment protein 2965566 dnaB 937396 dnaB Bacillus subtilis subsp. subtilis str. 168 replication initiation and membrane attachment protein NP_390777.1 2964148 R 224308 CDS NP_390778.1 16079952 937402 complement(2965681..2966139) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16950922; Product type r: regulator; transcriptional repressor NrdR 2966139 nrdR 937402 nrdR Bacillus subtilis subsp. subtilis str. 168 transcriptional repressor NrdR NP_390778.1 2965681 R 224308 CDS NP_390779.2 255767669 936773 complement(2966413..2966793) 1 NC_000964.3 Decarboxylation of S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine; S-adenosylmethionine decarboxylase proenzyme 2966793 speD 936773 speD Bacillus subtilis subsp. subtilis str. 168 S-adenosylmethionine decarboxylase proenzyme NP_390779.2 2966413 R 224308 CDS NP_390780.1 16079954 937393 complement(2967032..2968054) 1 NC_000964.3 NADP-dependent; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; active during gluconeogenesis; glyceraldehyde-3-phosphate dehydrogenase 2 2968054 gapB 937393 gapB Bacillus subtilis subsp. subtilis str. 168 glyceraldehyde-3-phosphate dehydrogenase 2 NP_390780.1 2967032 R 224308 CDS NP_390781.1 16079955 936607 complement(2968260..2968640) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HxlR family transcriptional regulator 2968640 ytcD 936607 ytcD Bacillus subtilis subsp. subtilis str. 168 HxlR family transcriptional regulator NP_390781.1 2968260 R 224308 CDS NP_390782.1 16079956 936655 2968824..2970014 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 2970014 ytbD 936655 ytbD Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_390782.1 2968824 D 224308 CDS NP_390783.1 16079957 937384 2970038..2970880 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 2970880 ytbE 937384 ytbE Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390783.1 2970038 D 224308 CDS NP_390784.1 16079958 937388 complement(2970922..2971515) 1 NC_000964.3 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 2971515 coaE 937388 coaE Bacillus subtilis subsp. subtilis str. 168 dephospho-CoA kinase NP_390784.1 2970922 R 224308 CDS NP_390785.2 255767670 937389 complement(2971531..2972163) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 2972163 ytaF 937389 ytaF Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390785.2 2971531 R 224308 CDS NP_390786.2 255767671 936741 complement(2972329..2973159) 1 NC_000964.3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 2973159 mutM 936741 mutM Bacillus subtilis subsp. subtilis str. 168 formamidopyrimidine-DNA glycosylase NP_390786.2 2972329 R 224308 CDS NP_390787.1 16079961 936617 complement(2973182..2975824) 1 NC_000964.3 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 2975824 polA 936617 polA Bacillus subtilis subsp. subtilis str. 168 DNA polymerase I NP_390787.1 2973182 R 224308 CDS NP_390788.1 16079962 937387 complement(2976068..2977807) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10433720, 12486063, 14762014, 15205429, 16452408, 17085571; Product type rc : receptor; alkaline phosphatase synthesis sensor protein PhoR 2977807 phoR 937387 phoR Bacillus subtilis subsp. subtilis str. 168 alkaline phosphatase synthesis sensor protein PhoR NP_390788.1 2976068 R 224308 CDS NP_390789.2 255767672 936644 complement(2977800..2978522) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762014, 14973033, 15205429, 16030210, 16452408, 16816204; Product type r: regulator; alkaline phosphatase synthesis transcriptional regulatory protein PhoP 2978522 phoP 936644 phoP Bacillus subtilis subsp. subtilis str. 168 alkaline phosphatase synthesis transcriptional regulatory protein PhoP NP_390789.2 2977800 R 224308 CDS NP_390790.1 16079964 937385 complement(2978734..2979672) 1 NC_000964.3 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 2979672 mdh 937385 mdh Bacillus subtilis subsp. subtilis str. 168 malate dehydrogenase NP_390790.1 2978734 R 224308 CDS NP_390791.1 16079965 938183 complement(2979716..2980987) 1 NC_000964.3 Converts isocitrate to alpha ketoglutarate; isocitrate dehydrogenase 2980987 icd 938183 icd Bacillus subtilis subsp. subtilis str. 168 isocitrate dehydrogenase NP_390791.1 2979716 R 224308 CDS NP_390792.1 16079966 937381 complement(2981151..2982269) 1 NC_000964.3 catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; citrate synthase 2 2982269 citZ 937381 citZ Bacillus subtilis subsp. subtilis str. 168 citrate synthase 2 NP_390792.1 2981151 R 224308 CDS NP_390793.1 16079967 935947 complement(2982603..2983067) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 2983067 ytwI 935947 ytwI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390793.1 2982603 R 224308 CDS NP_390794.1 16079968 937380 2983164..2984279 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922, 15849754, 16850406; Product type pt: transporter; hypothetical protein 2984279 ytvI 937380 ytvI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390794.1 2983164 D 224308 CDS NP_390795.1 16079969 937382 complement(2984312..2984695) 1 NC_000964.3 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein; hypothetical protein 2984695 fxsA 937382 fxsA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390795.1 2984312 R 224308 CDS NP_390796.1 16079970 936596 complement(2984788..2986545) 1 NC_000964.3 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 2986545 pyk 936596 pyk Bacillus subtilis subsp. subtilis str. 168 pyruvate kinase NP_390796.1 2984788 R 224308 CDS NP_390797.1 16079971 937376 complement(2986588..2987547) 1 NC_000964.3 catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 2987547 pfkA 937376 pfkA Bacillus subtilis subsp. subtilis str. 168 6-phosphofructokinase NP_390797.1 2986588 R 224308 CDS NP_390798.1 16079972 936367 complement(2987731..2988708) 1 NC_000964.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha 2988708 accA 936367 accA Bacillus subtilis subsp. subtilis str. 168 acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha NP_390798.1 2987731 R 224308 CDS NP_390799.2 255767673 936186 complement(2988693..2989565) 1 NC_000964.3 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 2989565 accD 936186 accD Bacillus subtilis subsp. subtilis str. 168 acetyl-coenzyme A carboxylase carboxyl transferase subunit beta NP_390799.2 2988693 R 224308 CDS NP_390800.1 16079974 937378 complement(2989900..2991132) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16788182; Product type e: enzyme; NAD-dependent malic enzyme 4 2991132 ytsJ 937378 ytsJ Bacillus subtilis subsp. subtilis str. 168 NAD-dependent malic enzyme 4 NP_390800.1 2989900 R 224308 CDS NP_390801.1 16079975 936593 complement(2991269..2994616) 1 NC_000964.3 catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III subunit alpha 2994616 dnaE 936593 dnaE Bacillus subtilis subsp. subtilis str. 168 DNA polymerase III subunit alpha NP_390801.1 2991269 R 224308 CDS YP_003097771.1 255767674 8303067 2994756..2995097 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype; sporulation membrane protein YtrH 2995097 ytrH 8303067 ytrH Bacillus subtilis subsp. subtilis str. 168 sporulation membrane protein YtrH YP_003097771.1 2994756 D 224308 CDS NP_390802.2 255767675 937371 2995067..2995597 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12662922, 15547282; Product type ph : phenotype; sporulation protein 2995597 ytrI 937371 ytrI Bacillus subtilis subsp. subtilis str. 168 sporulation protein NP_390802.2 2995067 D 224308 CDS YP_003097772.1 255767676 8303031 2995699..2995890 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2995890 ytzJ 8303031 ytzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097772.1 2995699 D 224308 CDS NP_390803.1 16079977 935963 complement(2995908..2996849) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17586819; Product type e: enzyme; bifunctional oligoribonuclease and PAP phosphatase NrnA 2996849 nrnA 935963 nrnA Bacillus subtilis subsp. subtilis str. 168 bifunctional oligoribonuclease and PAP phosphatase NrnA NP_390803.1 2995908 R 224308 CDS NP_390804.1 16079978 937370 2996980..2997282 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 2997282 ytpI 937370 ytpI Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390804.1 2996980 D 224308 CDS NP_390805.1 16079979 935941 complement(2997301..2998620) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 2998620 ytoI 935941 ytoI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390805.1 2997301 R 224308 CDS NP_390806.1 16079980 937366 complement(2998796..2999698) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 2999698 ytnM 937366 ytnM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390806.1 2998796 R 224308 CDS NP_390807.1 16079981 936157 complement(2999717..3000967) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10588044, 10939241, 11423008, 16109943; Product type pe: enzyme; hydrolase YtnL 3000967 ytnL 936157 ytnL Bacillus subtilis subsp. subtilis str. 168 hydrolase YtnL NP_390807.1 2999717 R 224308 CDS NP_390808.1 16079982 937367 complement(3000985..3001677) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15668000, 16109943, 17590224; Product type e: enzyme; RNA-binding riboflavin kinase RibR 3001677 rbfK 937367 rbfK Bacillus subtilis subsp. subtilis str. 168 RNA-binding riboflavin kinase RibR NP_390808.1 3000985 R 224308 CDS NP_390809.1 16079983 937365 complement(3001724..3003052) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; monooxygenase MoxC 3003052 ytnJ 937365 ytnJ Bacillus subtilis subsp. subtilis str. 168 monooxygenase MoxC NP_390809.1 3001724 R 224308 CDS NP_390810.1 16079984 936632 complement(3003049..3003330) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; glutaredoxin YtnI 3003330 ytnI 936632 ytnI Bacillus subtilis subsp. subtilis str. 168 glutaredoxin YtnI NP_390810.1 3003049 R 224308 CDS NP_390811.1 16079985 936618 complement(3003345..3004349) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241, 11423008, 16109943; Product type pe: enzyme; hypothetical protein 3004349 ytmO 936618 ytmO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390811.1 3003345 R 224308 CDS NP_390812.1 16079986 937364 complement(3004346..3005125) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine import ATP-binding protein TcyN 3005125 tcyN 937364 tcyN Bacillus subtilis subsp. subtilis str. 168 L-cystine import ATP-binding protein TcyN NP_390812.1 3004346 R 224308 CDS NP_390813.1 16079987 935938 complement(3005122..3005829) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter; L-cystine transport system permease protein TcyM 3005829 tcyM 935938 tcyM Bacillus subtilis subsp. subtilis str. 168 L-cystine transport system permease protein TcyM NP_390813.1 3005122 R 224308 CDS NP_390814.1 16079988 936115 complement(3005859..3006578) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924, 15849754, 16850406; Product type t : transporter; L-cystine transport system permease protein TcyL 3006578 tcyL 936115 tcyL Bacillus subtilis subsp. subtilis str. 168 L-cystine transport system permease protein TcyL NP_390814.1 3005859 R 224308 CDS NP_390815.1 16079989 937359 complement(3006600..3007412) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine-binding protein TcyK 3007412 tcyK 937359 tcyK Bacillus subtilis subsp. subtilis str. 168 L-cystine-binding protein TcyK NP_390815.1 3006600 R 224308 CDS NP_390816.1 16079990 937354 complement(3007426..3008235) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 11423008, 15262924; Product type t: transporter; L-cystine-binding protein TcyJ 3008235 tcyJ 937354 tcyJ Bacillus subtilis subsp. subtilis str. 168 L-cystine-binding protein TcyJ NP_390816.1 3007426 R 224308 CDS NP_390817.1 16079991 937353 complement(3008249..3008785) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11390694, 11423008, 16109943; Product type pe: enzyme; N-acetyltransferase YtmI 3008785 ytmI 937353 ytmI Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YtmI NP_390817.1 3008249 R 224308 CDS NP_390818.1 16079992 938452 3008938..3009864 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11390694, 11423008, 16109943, 16513748; Product type r: regulator; LysR family transcriptional regulator 3009864 ytlI 938452 ytlI Bacillus subtilis subsp. subtilis str. 168 LysR family transcriptional regulator NP_390818.1 3008938 D 224308 CDS NP_390819.2 50812279 936598 complement(3009915..3010598) 1 NC_000964.3 catalyzes the opening and hydrolysis of the beta-lactam ring of beta-lactam antibiotics such as penicillins and cephalosporins; metal-dependent hydrolase 3010598 ytkL 936598 ytkL Bacillus subtilis subsp. subtilis str. 168 metal-dependent hydrolase NP_390819.2 3009915 R 224308 CDS NP_390820.1 16079994 937351 complement(3010661..3011428) 1 NC_000964.3 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; oxidoreductase 3011428 fabG 937351 fabG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390820.1 3010661 R 224308 CDS NP_390821.2 255767677 936667 complement(3011555..3011689) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 11423008; hypothetical protein 3011689 ytzD 936667 ytzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390821.2 3011555 R 224308 CDS NP_390822.1 16079996 937966 complement(3011751..3013136) 1 NC_000964.3 catalyzes the formation of arginine from (N-L-arginino)succinate; argininosuccinate lyase 3013136 argH 937966 argH Bacillus subtilis subsp. subtilis str. 168 argininosuccinate lyase NP_390822.1 3011751 R 224308 CDS NP_390823.1 16079997 937348 complement(3013133..3014344) 1 NC_000964.3 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; argininosuccinate synthase 3014344 argG 937348 argG Bacillus subtilis subsp. subtilis str. 168 argininosuccinate synthase NP_390823.1 3013133 R 224308 CDS NP_390824.1 16079998 937349 complement(3014514..3015026) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15269205; Product type f: factor; molybdenum cofactor biosynthesis protein B 3015026 moaB 937349 moaB Bacillus subtilis subsp. subtilis str. 168 molybdenum cofactor biosynthesis protein B NP_390824.1 3014514 R 224308 CDS NP_390825.1 16079999 937347 complement(3015111..3016298) 1 NC_000964.3 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase 3016298 ackA 937347 ackA Bacillus subtilis subsp. subtilis str. 168 acetate kinase NP_390825.1 3015111 R 224308 CDS NP_390826.1 16080000 938186 complement(3016646..3017635) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3017635 ytxK 938186 ytxK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390826.1 3016646 R 224308 CDS NP_390827.1 16080001 937688 complement(3017696..3018199) 1 NC_000964.3 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 3018199 tpx 937688 tpx Bacillus subtilis subsp. subtilis str. 168 thiol peroxidase NP_390827.1 3017696 R 224308 CDS NP_390828.1 16080002 937346 complement(3018309..3018764) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; spore protein YtfJ 3018764 ytfJ 937346 ytfJ Bacillus subtilis subsp. subtilis str. 168 spore protein YtfJ NP_390828.1 3018309 R 224308 CDS NP_390829.1 16080003 937342 complement(3018778..3019458) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3019458 ytfI 937342 ytfI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390829.1 3018778 R 224308 CDS NP_390830.1 16080004 937343 complement(3019533..3020027) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3020027 yteJ 937343 yteJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390830.1 3019533 R 224308 CDS NP_390831.1 16080005 937679 complement(3020040..3021047) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455123, 16484219, 9987136; Product type e: enzyme; signal peptide peptidase SppA 3021047 sppA 937679 sppA Bacillus subtilis subsp. subtilis str. 168 signal peptide peptidase SppA NP_390831.1 3020040 R 224308 CDS NP_390832.1 16080006 936767 3021233..3022036 1 NC_000964.3 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 2 3022036 ppnK 936767 ppnK Bacillus subtilis subsp. subtilis str. 168 inorganic polyphosphate/ATP-NAD kinase 2 NP_390832.1 3021233 D 224308 CDS NP_390833.1 16080007 936723 complement(3022068..3023657) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; amidohydrolase YtcJ 3023657 ytcJ 936723 ytcJ Bacillus subtilis subsp. subtilis str. 168 amidohydrolase YtcJ NP_390833.1 3022068 R 224308 CDS NP_390834.2 255767678 937336 complement(3023677..3025266) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acyl--CoA ligase 3025266 ytcI 937336 ytcI Bacillus subtilis subsp. subtilis str. 168 acyl--CoA ligase NP_390834.2 3023677 R 224308 CDS NP_390835.1 16080009 937338 complement(3025445..3025654) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707666, 2456528, 2468649, 3009398; Product type cp: cell process; small acid-soluble spore protein A 3025654 sspA 937338 sspA Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein A NP_390835.1 3025445 R 224308 CDS NP_390836.2 255767679 937471 complement(3025748..3026953) 1 NC_000964.3 Required for the synthesis of the thiazole moiety; tRNA sulfurtransferase 3026953 ytbJ 937471 ytbJ Bacillus subtilis subsp. subtilis str. 168 tRNA sulfurtransferase NP_390836.2 3025748 R 224308 CDS NP_390837.1 16080011 937701 complement(3026957..3028102) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10939241, 11443125, 13129955, 14757766, 16388576, 17237162; Product type e: enzyme; cysteine desulfurase IscS 2 3028102 iscS 937701 iscS Bacillus subtilis subsp. subtilis str. 168 cysteine desulfurase IscS 2 NP_390837.1 3026957 R 224308 CDS NP_390838.1 16080012 937334 3028297..3029634 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11528000, 15849754, 16850406; Product type t : transporter; branched-chain amino acid transport system carrier protein BraB 3029634 braB 937334 braB Bacillus subtilis subsp. subtilis str. 168 branched-chain amino acid transport system carrier protein BraB NP_390838.1 3028297 D 224308 CDS NP_390839.1 16080013 937337 complement(3029729..3031417) 1 NC_000964.3 acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 3031417 ezrA 937337 ezrA Bacillus subtilis subsp. subtilis str. 168 septation ring formation regulator EzrA NP_390839.1 3029729 R 224308 CDS NP_390840.1 16080014 937924 3031614..3032420 1 NC_000964.3 catalyzes the formation of L-histidinol from L-histidinol phosphate; histidinol-phosphatase 3032420 hisJ 937924 hisJ Bacillus subtilis subsp. subtilis str. 168 histidinol-phosphatase NP_390840.1 3031614 D 224308 CDS NP_390841.1 16080015 937327 complement(3032417..3033040) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534; Product type pr : regulator; TetR family transcriptional regulator 3033040 yttP 937327 yttP Bacillus subtilis subsp. subtilis str. 168 TetR family transcriptional regulator NP_390841.1 3032417 R 224308 CDS NP_390842.2 255767680 936758 3033167..3033658 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3033658 ytsP 936758 ytsP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390842.2 3033167 D 224308 CDS NP_390843.1 16080017 936255 complement(3033696..3035435) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; diguanylate cyclase 3035435 dgcP 936255 dgcP Bacillus subtilis subsp. subtilis str. 168 diguanylate cyclase NP_390843.1 3033696 R 224308 CDS NP_390844.1 16080018 937319 3035730..3036332 1 NC_000964.3 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 3036332 rpsD 937319 rpsD Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S4 NP_390844.1 3035730 D 224308 CDS NP_390845.1 16080019 938185 complement(3036603..3037871) 1 NC_000964.3 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosine--tRNA ligase 1 3037871 tyrS 938185 tyrS Bacillus subtilis subsp. subtilis str. 168 tyrosine--tRNA ligase 1 NP_390845.1 3036603 R 224308 CDS YP_003097773.1 255767681 8303078 complement(3038060..3038203) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3038203 ytzK 8303078 ytzK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097773.1 3038060 R 224308 CDS NP_390846.1 16080020 937324 complement(3038213..3039931) 1 NC_000964.3 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA; acetyl-coenzyme A synthetase 3039931 acsA 937324 acsA Bacillus subtilis subsp. subtilis str. 168 acetyl-coenzyme A synthetase NP_390846.1 3038213 R 224308 CDS NP_390847.1 16080021 937633 3040092..3040724 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 18487328, 7934817; Product type e : enzyme; acetoin utilization protein AcuA 3040724 acuA 937633 acuA Bacillus subtilis subsp. subtilis str. 168 acetoin utilization protein AcuA NP_390847.1 3040092 D 224308 CDS NP_390848.1 16080022 937318 3040751..3041395 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type f: factor; acetoin utilization protein AcuB 3041395 acuB 937318 acuB Bacillus subtilis subsp. subtilis str. 168 acetoin utilization protein AcuB NP_390848.1 3040751 D 224308 CDS NP_390849.1 16080023 936834 3041392..3042555 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10368162, 10809684, 11274109, 16855235, 7934817; Product type e: enzyme; acetoin utilization protein AcuC 3042555 acuC 936834 acuC Bacillus subtilis subsp. subtilis str. 168 acetoin utilization protein AcuC NP_390849.1 3041392 D 224308 CDS NP_390850.1 16080024 937315 complement(3042566..3043294) 1 NC_000964.3 Homolog of MotB, appears to be involved in motility on surfaces or under specific ionic conditions. With MotP (a Mot A homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; hypothetical protein 3043294 ytxE 937315 ytxE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390850.1 3042566 R 224308 CDS NP_390851.1 16080025 937317 complement(3043284..3044102) 1 NC_000964.3 Homolog of MotA, appears to be involved in motility on surfaces and under different ionic conditions. With MotS (a MotB homolog) forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine.; hypothetical protein 3044102 ytxD 937317 ytxD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390851.1 3043284 R 224308 CDS NP_390852.1 16080026 935942 complement(3044165..3045169) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11931564, 14665673, 16316990, 17085448; Product type r: regulator; catabolite control protein A 3045169 ccpA 935942 ccpA Bacillus subtilis subsp. subtilis str. 168 catabolite control protein A NP_390852.1 3044165 R 224308 CDS NP_390853.1 16080027 937853 complement(3045445..3046521) 1 NC_000964.3 catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; 5-enolpyruvylshikimate-3-phosphate synthetase AroA 3046521 aroA 937853 aroA Bacillus subtilis subsp. subtilis str. 168 5-enolpyruvylshikimate-3-phosphate synthetase AroA NP_390853.1 3045445 R 224308 CDS NP_390854.1 16080028 937308 complement(3046757..3047083) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232; hypothetical protein 3047083 ytxJ 937308 ytxJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390854.1 3046757 R 224308 CDS NP_390855.2 255767682 937312 complement(3047107..3047562) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16291680, 8733232; hypothetical protein 3047562 ytxH 937312 ytxH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390855.2 3047107 R 224308 CDS NP_390856.2 255767683 937386 complement(3047593..3048015) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8733232; hypothetical protein 3048015 ytxG 937386 ytxG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390856.2 3047593 R 224308 CDS NP_390857.1 16080031 937311 complement(3048177..3049475) 1 NC_000964.3 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase 3049475 murC 937311 murC Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylmuramate--L-alanine ligase NP_390857.1 3048177 R 224308 CDS NP_390859.2 255767684 938522 complement(3049725..3052583) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11134515, 11208805, 3129532; Product type pe: enzyme; DNA translocase SftA 3052583 ytpS 938522 ytpS Bacillus subtilis subsp. subtilis str. 168 DNA translocase SftA NP_390859.2 3049725 R 224308 CDS NP_390860.1 16080034 937964 complement(3052743..3053348) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; tRNA-binding protein YtpR 3053348 ytpR 937964 ytpR Bacillus subtilis subsp. subtilis str. 168 tRNA-binding protein YtpR NP_390860.1 3052743 R 224308 CDS NP_390861.1 16080035 937506 complement(3053364..3054173) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520; hypothetical protein 3054173 ytpQ 937506 ytpQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390861.1 3053364 R 224308 CDS NP_390862.1 16080036 936697 complement(3054188..3054511) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12719520, 15937154; Product type pe: enzyme; thioredoxin 3054511 ytpP 936697 ytpP Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_390862.1 3054188 R 224308 CDS NP_390863.1 16080037 937302 3054746..3055192 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3055192 ytoQ 937302 ytoQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390863.1 3054746 D 224308 CDS NP_390864.1 16080038 937301 complement(3055247..3056320) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8535515; Product type e: enzyme; aminopeptidase YtoP 3056320 ytoP 937301 ytoP Bacillus subtilis subsp. subtilis str. 168 aminopeptidase YtoP NP_390864.1 3055247 R 224308 CDS NP_390865.1 16080039 937300 3056479..3056796 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3056796 ytzB 937300 ytzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390865.1 3056479 D 224308 CDS NP_390866.1 16080040 938071 complement(3056849..3058549) 1 NC_000964.3 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; NAD-dependent malic enzyme 3 3058549 malS 938071 malS Bacillus subtilis subsp. subtilis str. 168 NAD-dependent malic enzyme 3 NP_390866.1 3056849 R 224308 CDS NP_390867.1 16080041 937981 complement(3058631..3059401) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3059401 ytnP 937981 ytnP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390867.1 3058631 R 224308 CDS NP_390868.1 16080042 936447 complement(3059547..3060188) 1 NC_000964.3 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 3060188 trmB 936447 trmB Bacillus subtilis subsp. subtilis str. 168 tRNA (guanine-N(7)-)-methyltransferase NP_390868.1 3059547 R 224308 CDS NP_390869.1 16080043 937298 3060395..3060673 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3060673 ytzH 937298 ytzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390869.1 3060395 D 224308 CDS NP_390870.2 255767685 936622 complement(3060674..3061288) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11545674, 9026440; Product type pe: enzyme; phosphotransferase YtmP 3061288 ytmP 936622 ytmP Bacillus subtilis subsp. subtilis str. 168 phosphotransferase YtmP NP_390870.2 3060674 R 224308 CDS NP_390871.2 255767686 937292 complement(3061651..3063807) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16582490, 9453151; Product type e: enzyme; pullulanase 3063807 amyX 937292 amyX Bacillus subtilis subsp. subtilis str. 168 pullulanase NP_390871.2 3061651 R 224308 CDS NP_390872.1 16080046 937289 complement(3063833..3064762) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lipid kinase YtlR 3064762 ytlR 937289 ytlR Bacillus subtilis subsp. subtilis str. 168 lipid kinase YtlR NP_390872.1 3063833 R 224308 CDS NP_390873.1 16080047 938075 complement(3064811..3065725) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3065725 ytlQ 938075 ytlQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390873.1 3064811 R 224308 CDS NP_390874.1 16080048 937293 complement(3065751..3066302) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17012785; Product type s: structure; hypothetical protein 3066302 ytlP 937293 ytlP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390874.1 3065751 R 224308 CDS NP_390875.1 16080049 936733 3066451..3067386 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16267287; Product type pe: enzyme; cysteine synthase 3067386 ytkP 936733 ytkP Bacillus subtilis subsp. subtilis str. 168 cysteine synthase NP_390875.1 3066451 D 224308 CDS NP_390876.1 16080050 937290 complement(3067420..3068811) 1 NC_000964.3 divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase YtjP 3068811 ytjP 937290 ytjP Bacillus subtilis subsp. subtilis str. 168 dipeptidase YtjP NP_390876.1 3067420 R 224308 CDS NP_390877.1 16080051 938070 3068908..3070206 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591660, 15849754, 16850406; Product type t: transporter; guanine/hypoxanthine permease PbuO 3070206 pbuO 938070 pbuO Bacillus subtilis subsp. subtilis str. 168 guanine/hypoxanthine permease PbuO NP_390877.1 3068908 D 224308 CDS NP_390878.1 16080052 937288 complement(3070246..3071403) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3071403 ythQ 937288 ythQ Bacillus subtilis subsp. subtilis str. 168 transporter NP_390878.1 3070246 R 224308 CDS NP_390879.1 16080053 937282 complement(3071400..3072110) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3072110 ythP 937282 ythP Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_390879.1 3071400 R 224308 CDS NP_390880.1 16080054 937281 3072401..3072622 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618461; Product type pr : regulator; DeoR family transcriptional regulator 3072622 ytzE 937281 ytzE Bacillus subtilis subsp. subtilis str. 168 DeoR family transcriptional regulator NP_390880.1 3072401 D 224308 CDS NP_390882.2 255767687 936165 complement(3072743..3073462) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; RNA pseudouridine synthase 3073462 ytzG 936165 ytzG Bacillus subtilis subsp. subtilis str. 168 RNA pseudouridine synthase NP_390882.2 3072743 R 224308 CDS NP_390883.1 16080057 937937 complement(3073531..3075165) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11254558, 15044829, 15849754, 16850406; Product type pe: enzyme; cell division protein YtgP 3075165 ytgP 937937 ytgP Bacillus subtilis subsp. subtilis str. 168 cell division protein YtgP NP_390883.1 3073531 R 224308 CDS NP_390884.2 255767688 937280 3075367..3076629 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3076629 ytfP 937280 ytfP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390884.2 3075367 D 224308 CDS NP_390885.1 16080059 937986 3076818..3078356 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14996799, 15849754, 16850406, 8752321, 9925583; Product type t: transporter; glycine betaine transporter OpuD 3078356 opuD 937986 opuD Bacillus subtilis subsp. subtilis str. 168 glycine betaine transporter OpuD NP_390885.1 3076818 D 224308 CDS NP_390886.1 16080060 937278 complement(3078393..3078575) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 8990290; sporulation protein cse60 3078575 yteV 937278 yteV Bacillus subtilis subsp. subtilis str. 168 sporulation protein cse60 NP_390886.1 3078393 R 224308 CDS NP_390887.1 16080061 936405 complement(3078643..3079311) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17449691; Product type pe: enzyme; hypothetical protein 3079311 yteU 936405 yteU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390887.1 3078643 R 224308 CDS NP_390888.1 16080062 937274 complement(3079333..3080619) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type pe : enzyme; oxidoreductase 3080619 yteT 937274 yteT Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390888.1 3079333 R 224308 CDS NP_390889.2 255767689 937272 complement(3080631..3081134) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17449691; Product type lp : lipoprotein; lipoprotein 3081134 yteS 937272 yteS Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_390889.2 3080631 R 224308 CDS NP_390890.2 255767690 937273 complement(3081131..3082243) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15148314, 15906318, 16781735, 16870154, 17449691; Product type e: enzyme; rhamnogalacturonyl hydrolase 3082243 yteR 937273 yteR Bacillus subtilis subsp. subtilis str. 168 rhamnogalacturonyl hydrolase NP_390890.2 3081131 R 224308 CDS NP_390892.2 255767691 937271 complement(3082260..3083225) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; multiple-sugar transport system permease YteP 3083225 yteP 937271 yteP Bacillus subtilis subsp. subtilis str. 168 multiple-sugar transport system permease YteP NP_390892.2 3082260 R 224308 CDS NP_390893.1 16080067 936234 3083441..3085759 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AraC family transcriptional regulator 3085759 ytdP 936234 ytdP Bacillus subtilis subsp. subtilis str. 168 AraC family transcriptional regulator NP_390893.1 3083441 D 224308 CDS NP_390894.3 255767692 938090 complement(3085800..3087296) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; peptide ABC transporter substrate-binding protein 3087296 ytcQ 938090 ytcQ Bacillus subtilis subsp. subtilis str. 168 peptide ABC transporter substrate-binding protein NP_390894.3 3085800 R 224308 CDS NP_390895.1 16080069 938095 complement(3087321..3088181) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3088181 ytcP 938095 ytcP Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390895.1 3087321 R 224308 CDS NP_390896.2 255767693 937270 complement(3088388..3089149) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3089149 ytbQ 937270 ytbQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390896.2 3088388 R 224308 CDS NP_390897.1 16080071 935928 complement(3089226..3090413) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11368323; Product type e: enzyme; biotin biosynthesis cytochrome P450 3090413 bioI 935928 bioI Bacillus subtilis subsp. subtilis str. 168 biotin biosynthesis cytochrome P450 NP_390897.1 3089226 R 224308 CDS NP_390898.1 16080072 938180 complement(3090482..3091489) 1 NC_000964.3 catalyzes the formation of biotin from dethiobiotin and sulfur 2 S-adenosyl-L-methionine; biotin synthase 3091489 bioB 938180 bioB Bacillus subtilis subsp. subtilis str. 168 biotin synthase NP_390898.1 3090482 R 224308 CDS NP_390899.1 16080073 937264 complement(3091492..3092187) 1 NC_000964.3 DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium; ATP-dependent dethiobiotin synthetase BioD 3092187 bioD 937264 bioD Bacillus subtilis subsp. subtilis str. 168 ATP-dependent dethiobiotin synthetase BioD NP_390899.1 3091492 R 224308 CDS NP_390900.1 16080074 937268 complement(3092184..3093353) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717296, 12368242, 8763940; Product type e: enzyme; 8-amino-7-oxononanoate synthase 3093353 bioF 937268 bioF Bacillus subtilis subsp. subtilis str. 168 8-amino-7-oxononanoate synthase NP_390900.1 3092184 R 224308 CDS NP_390901.1 16080075 936286 complement(3093343..3094689) 1 NC_000964.3 catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate; L-lysine-8-amino-7-oxononanoate aminotransferase 3094689 bioA 936286 bioA Bacillus subtilis subsp. subtilis str. 168 L-lysine-8-amino-7-oxononanoate aminotransferase NP_390901.1 3093343 R 224308 CDS NP_390902.3 255767694 938017 complement(3094679..3095455) 1 NC_000964.3 catalyzes the formation of pimeloyl-CoA from pimelate and coenzyme A; 6-carboxyhexanoate--CoA ligase 3095455 bioW 938017 bioW Bacillus subtilis subsp. subtilis str. 168 6-carboxyhexanoate--CoA ligase NP_390902.3 3094679 R 224308 CDS NP_390903.1 16080077 937263 complement(3095665..3096564) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase YtaP 3096564 ytaP 937263 ytaP Bacillus subtilis subsp. subtilis str. 168 hydrolase YtaP NP_390903.1 3095665 R 224308 CDS NP_390904.1 16080078 937257 3096782..3097816 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288; Product type r: regulator; LacI family transcriptional regulator 3097816 msmR 937257 msmR Bacillus subtilis subsp. subtilis str. 168 LacI family transcriptional regulator NP_390904.1 3096782 D 224308 CDS NP_390905.1 16080079 936693 3097850..3099130 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 16707683; Product type lp : lipoprotein; sugar ABC transporter substrate-binding protein 3099130 msmE 936693 msmE Bacillus subtilis subsp. subtilis str. 168 sugar ABC transporter substrate-binding protein NP_390905.1 3097850 D 224308 CDS NP_390906.1 16080080 937258 3099123..3100034 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12847288, 1537846, 15849754, 16707683, 16850406; Product type t: transporter; ABC transporter permease 3100034 amyD 937258 amyD Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390906.1 3099123 D 224308 CDS NP_390907.1 16080081 935927 3100031..3100861 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1537846, 15849754, 16707683, 16850406; Product type t: transporter; ABC transporter permease 3100861 amyC 935927 amyC Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390907.1 3100031 D 224308 CDS NP_390908.1 16080082 937255 3100881..3102179 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12847288; Product type e: enzyme; alpha-galactosidase 3102179 melA 937255 melA Bacillus subtilis subsp. subtilis str. 168 alpha-galactosidase NP_390908.1 3100881 D 224308 CDS NP_390909.2 255767695 936589 complement(3102201..3102512) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10939241; Product type pe : enzyme; hypothetical protein 3102512 ytwF 936589 ytwF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390909.2 3102201 R 224308 CDS NP_390910.1 16080084 938102 complement(3102629..3105043) 1 NC_000964.3 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucine--tRNA ligase 3105043 leuS 938102 leuS Bacillus subtilis subsp. subtilis str. 168 leucine--tRNA ligase NP_390910.1 3102629 R 224308 CDS NP_390911.2 255767696 937249 complement(3105470..3105799) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16923906; Product type pm : membrane component; hypothetical protein 3105799 ytvB 937249 ytvB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390911.2 3105470 R 224308 CDS NP_390912.1 16080086 937254 3106210..3106995 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11964249, 16923906, 16923909, 17200735, 17443319, 17575448; Product type rc : receptor; blue-light photoreceptor 3106995 ytvA 937254 ytvA Bacillus subtilis subsp. subtilis str. 168 blue-light photoreceptor NP_390912.1 3106210 D 224308 CDS NP_390913.1 16080087 936526 complement(3107232..3108425) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11988534, 15849754, 16850406; Product type pt: transporter; MFS transporter 3108425 yttB 936526 yttB Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_390913.1 3107232 R 224308 CDS NP_390914.2 255767697 937248 3108614..3109360 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818; membrane protein 3109360 yttA 937248 yttA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390914.2 3108614 D 224308 CDS NP_390915.1 16080089 938178 complement(3109397..3111337) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 15849754, 16850406, 17905982; Product type t: transporter; bacitracin export permease protein BceB 3111337 bceB 938178 bceB Bacillus subtilis subsp. subtilis str. 168 bacitracin export permease protein BceB NP_390915.1 3109397 R 224308 CDS NP_390916.1 16080090 937246 complement(3111327..3112088) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14612242, 17905982; Product type t: transporter; bacitracin export ATP-binding protein BceA 3112088 bceA 937246 bceA Bacillus subtilis subsp. subtilis str. 168 bacitracin export ATP-binding protein BceA NP_390916.1 3111327 R 224308 CDS NP_390917.1 16080091 936816 complement(3112190..3113194) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type rc: receptor; sensor protein BceS 3113194 bceS 936816 bceS Bacillus subtilis subsp. subtilis str. 168 sensor protein BceS NP_390917.1 3112190 R 224308 CDS NP_390918.1 16080092 936307 complement(3113187..3113882) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 17905982; Product type r: regulator; sensory transduction protein BceR 3113882 bceR 936307 bceR Bacillus subtilis subsp. subtilis str. 168 sensory transduction protein BceR NP_390918.1 3113187 R 224308 CDS NP_390919.1 16080093 937247 complement(3113979..3115289) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease 3115289 ytrF 937247 ytrF Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390919.1 3113979 R 224308 CDS NP_390920.1 16080094 937245 complement(3115279..3115974) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter; ABC transporter ATP-binding protein 3115974 ytrE 937245 ytrE Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_390920.1 3115279 R 224308 CDS NP_390921.1 16080095 936438 complement(3115989..3116966) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease 3116966 ytrD 936438 ytrD Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390921.1 3115989 R 224308 CDS NP_390922.1 16080096 937243 complement(3116996..3117982) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 15849754, 16850406; Product type t: transporter; ABC transporter permease 3117982 ytrC 937243 ytrC Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390922.1 3116996 R 224308 CDS NP_390923.1 16080097 936641 complement(3117976..3118854) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249; Product type t: transporter; ABC transporter ATP-binding protein 3118854 ytrB 936641 ytrB Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_390923.1 3117976 R 224308 CDS NP_390924.1 16080098 937244 complement(3118847..3119239) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10986249, 11756427, 17194626; Product type r: regulator; GntR family transcriptional regulator 3119239 ytrA 937244 ytrA Bacillus subtilis subsp. subtilis str. 168 GntR family transcriptional regulator NP_390924.1 3118847 R 224308 CDS NP_390925.1 16080099 936521 complement(3119565..3119837) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3119837 ytzC 936521 ytzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390925.1 3119565 R 224308 CDS NP_390926.1 16080100 937240 3119999..3120967 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; radical SAM protein YtqA 3120967 ytqA 937240 ytqA Bacillus subtilis subsp. subtilis str. 168 radical SAM protein YtqA NP_390926.1 3119999 D 224308 CDS NP_390927.1 16080101 938058 3120964..3121548 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16014871; Product type pe : enzyme; rRNA methylase YtqB 3121548 ytqB 938058 ytqB Bacillus subtilis subsp. subtilis str. 168 rRNA methylase YtqB NP_390927.1 3120964 D 224308 CDS NP_390928.1 16080102 936222 complement(3121538..3122641) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; tetraprenyl-beta-curcumene synthase 3122641 ytpB 936222 ytpB Bacillus subtilis subsp. subtilis str. 168 tetraprenyl-beta-curcumene synthase NP_390928.1 3121538 R 224308 CDS NP_390929.1 16080103 937237 complement(3122662..3123441) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11796336; Product type e: enzyme; phospholipase YtpA 3123441 ytpA 937237 ytpA Bacillus subtilis subsp. subtilis str. 168 phospholipase YtpA NP_390929.1 3122662 R 224308 CDS NP_390930.1 16080104 937238 3123490..3124005 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; transferase YtoA 3124005 ytoA 937238 ytoA Bacillus subtilis subsp. subtilis str. 168 transferase YtoA NP_390930.1 3123490 D 224308 CDS NP_390931.1 16080105 938118 complement(3124250..3125641) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10498721, 15849754, 16850406; Product type pt: transporter; amino acid permease YtnA 3125641 ytnA 938118 ytnA Bacillus subtilis subsp. subtilis str. 168 amino acid permease YtnA NP_390931.1 3124250 R 224308 CDS NP_390932.1 16080106 937236 complement(3125777..3127675) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721; Product type e: enzyme; asparagine synthetase 1 3127675 asnB 937236 asnB Bacillus subtilis subsp. subtilis str. 168 asparagine synthetase 1 NP_390932.1 3125777 R 224308 CDS NP_390933.1 16080107 937090 complement(3127825..3129027) 1 NC_000964.3 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthase 3129027 metK 937090 metK Bacillus subtilis subsp. subtilis str. 168 S-adenosylmethionine synthase NP_390933.1 3127825 R 224308 CDS NP_390934.2 255767698 937235 3129530..3131113 1 NC_000964.3 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP; phosphoenolpyruvate carboxykinase 3131113 pckA 937235 pckA Bacillus subtilis subsp. subtilis str. 168 phosphoenolpyruvate carboxykinase NP_390934.2 3129530 D 224308 CDS NP_390935.1 16080109 937228 complement(3131152..3131394) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3131394 ytmB 937228 ytmB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390935.1 3131152 R 224308 CDS NP_390936.1 16080110 936383 complement(3131446..3132219) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; peptidase YtmA 3132219 ytmA 936383 ytmA Bacillus subtilis subsp. subtilis str. 168 peptidase YtmA NP_390936.1 3131446 R 224308 CDS NP_390937.2 255767699 935959 3132370..3133374 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; binding protein YtlA 3133374 ytlA 935959 ytlA Bacillus subtilis subsp. subtilis str. 168 binding protein YtlA NP_390937.2 3132370 D 224308 CDS NP_390939.1 16080113 937218 3133387..3134169 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3134169 ytlC 937218 ytlC Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_390939.1 3133387 D 224308 CDS NP_390940.1 16080114 937097 3134144..3134956 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3134956 ytlD 937097 ytlD Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_390940.1 3134144 D 224308 CDS NP_390941.1 16080115 937072 complement(3134983..3135459) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576788, 16513759; Product type e: enzyme; 8-oxo-dGTP diphosphatase YtkD 3135459 ytkD 937072 ytkD Bacillus subtilis subsp. subtilis str. 168 8-oxo-dGTP diphosphatase YtkD NP_390941.1 3134983 R 224308 CDS NP_390942.1 16080116 937209 complement(3135668..3136072) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type h: extrachromosomal origin; hypothetical protein 3136072 ytkC 937209 ytkC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390942.1 3135668 R 224308 CDS NP_390943.1 16080117 937211 complement(3136238..3136675) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12767829, 16091047, 16861227, 16935006; Product type e: enzyme; general stress protein 20U 3136675 dps 937211 dps Bacillus subtilis subsp. subtilis str. 168 general stress protein 20U NP_390943.1 3136238 R 224308 CDS YP_003097774.1 255767700 8302972 3136768..3136944 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 3136944 ytzI 8302972 ytzI Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097774.1 3136768 D 224308 CDS NP_390944.1 16080118 937181 complement(3136938..3137375) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 3137375 ytkA 937181 ytkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390944.1 3136938 R 224308 CDS NP_390945.1 16080119 937106 complement(3137495..3137968) 1 NC_000964.3 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteine lyase 3137968 luxS 937106 luxS Bacillus subtilis subsp. subtilis str. 168 S-ribosylhomocysteine lyase NP_390945.1 3137495 R 224308 CDS NP_390946.1 16080120 937207 3138097..3138324 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein insertion efficiency factor 3138324 ytjA 937207 ytjA Bacillus subtilis subsp. subtilis str. 168 membrane protein insertion efficiency factor NP_390946.1 3138097 D 224308 CDS NP_390947.1 16080121 938087 complement(3138321..3138884) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12193617; Product type e: enzyme; carbonic anhydrase YtiB 3138884 ytiB 938087 ytiB Bacillus subtilis subsp. subtilis str. 168 carbonic anhydrase YtiB NP_390947.1 3138321 R 224308 CDS NP_390948.1 16080122 937208 complement(3138978..3139226) 1 NC_000964.3 RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 type B 3139226 rpmE2 937208 rpmE2 Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L31 type B NP_390948.1 3138978 R 224308 CDS NP_390949.2 255767701 937142 3139431..3140762 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 17114254, 9852001; Product type pe: enzyme; cytochrome bd menaquinol oxidase subunit I 3140762 ythA 937142 ythA Bacillus subtilis subsp. subtilis str. 168 cytochrome bd menaquinol oxidase subunit I NP_390949.2 3139431 D 224308 CDS NP_390950.1 16080124 937206 3140806..3141846 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11073895, 15576792, 15849754, 16850406; Product type pe: enzyme; cytochrome bd menaquinol oxidase subunit II 3141846 ythB 937206 ythB Bacillus subtilis subsp. subtilis str. 168 cytochrome bd menaquinol oxidase subunit II NP_390950.1 3140806 D 224308 CDS YP_003097775.1 255767702 8303158 3141900..3142058 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3142058 ytzL 8303158 ytzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097775.1 3141900 D 224308 CDS NP_390952.1 16080126 937149 complement(3142077..3142964) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16566604, 16704341, 16850406; Product type t : transporter; manganese transport system membrane protein MntD 3142964 mntD 937149 mntD Bacillus subtilis subsp. subtilis str. 168 manganese transport system membrane protein MntD NP_390952.1 3142077 R 224308 CDS NP_390953.1 16080127 937203 complement(3142954..3144261) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 15948947, 16704341, 16850406; Product type t: transporter; manganese transport system membrane protein MntC 3144261 mntC 937203 mntC Bacillus subtilis subsp. subtilis str. 168 manganese transport system membrane protein MntC NP_390953.1 3142954 R 224308 CDS NP_390954.1 16080128 937196 complement(3144267..3145019) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type t: transporter; manganese transport system ATP-binding protein MntB 3145019 mntB 937196 mntB Bacillus subtilis subsp. subtilis str. 168 manganese transport system ATP-binding protein MntB NP_390954.1 3144267 R 224308 CDS NP_390955.1 16080129 937219 complement(3145038..3145958) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15948947, 16566604, 16704341; Product type lp: lipoprotein; manganese-binding lipoprotein MntA 3145958 mntA 937219 mntA Bacillus subtilis subsp. subtilis str. 168 manganese-binding lipoprotein MntA NP_390955.1 3145038 R 224308 CDS NP_390956.1 16080130 937201 complement(3146238..3147353) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 6780514, 8566759, 9139683; Product type e: enzyme; o-succinylbenzoate synthase 3147353 menC 937201 menC Bacillus subtilis subsp. subtilis str. 168 o-succinylbenzoate synthase NP_390956.1 3146238 R 224308 CDS NP_390957.1 16080131 937132 complement(3147350..3148810) 1 NC_000964.3 converts O-succinylbenzoate to O-succinylbenzoyl-CoA; 2-succinylbenzoate--CoA ligase 3148810 menE 937132 menE Bacillus subtilis subsp. subtilis str. 168 2-succinylbenzoate--CoA ligase NP_390957.1 3147350 R 224308 CDS NP_390958.1 16080132 937195 complement(3148901..3149716) 1 NC_000964.3 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA; 1,4-dihydroxy-2-naphthoyl-CoA synthase 3149716 menB 937195 menB Bacillus subtilis subsp. subtilis str. 168 1,4-dihydroxy-2-naphthoyl-CoA synthase NP_390958.1 3148901 R 224308 CDS NP_390959.1 16080133 937115 complement(3149751..3150575) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12454479; Product type pe : enzyme; esterase 3150575 ytxM 937115 ytxM Bacillus subtilis subsp. subtilis str. 168 esterase NP_390959.1 3149751 R 224308 CDS NP_390960.1 16080134 937198 complement(3150563..3152305) 1 NC_000964.3 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis; 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase 3152305 menD 937198 menD Bacillus subtilis subsp. subtilis str. 168 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase NP_390960.1 3150563 R 224308 CDS NP_390961.1 16080135 937190 complement(3152302..3153717) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 6780514, 8169214, 8566759; Product type e: enzyme; menaquinone-specific isochorismate synthase 3153717 menF 937190 menF Bacillus subtilis subsp. subtilis str. 168 menaquinone-specific isochorismate synthase NP_390961.1 3152302 R 224308 CDS NP_390962.2 50812282 937192 3154007..3154726 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15496987; hypothetical protein 3154726 yteA 937192 yteA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390962.2 3154007 D 224308 CDS NP_390963.1 16080137 937119 complement(3154735..3155553) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UTP--glucose-1-phosphate uridylyltransferase 3155553 ytdA 937119 ytdA Bacillus subtilis subsp. subtilis str. 168 UTP--glucose-1-phosphate uridylyltransferase NP_390963.1 3154735 R 224308 CDS NP_390964.1 16080138 936155 3155725..3157011 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucose 6-dehydrogenase YtcA 3157011 ytcA 936155 ytcA Bacillus subtilis subsp. subtilis str. 168 UDP-glucose 6-dehydrogenase YtcA NP_390964.1 3155725 D 224308 CDS NP_390965.1 16080139 938900 3157008..3157958 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UDP-glucose epimerase YtcB 3157958 ytcB 938900 ytcB Bacillus subtilis subsp. subtilis str. 168 UDP-glucose epimerase YtcB NP_390965.1 3157008 D 224308 CDS NP_390966.1 16080140 939212 3157961..3159184 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YtcC 3159184 ytcC 939212 ytcC Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YtcC NP_390966.1 3157961 D 224308 CDS NP_390967.1 16080141 936317 complement(3159258..3159689) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3159689 ytxO 936317 ytxO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390967.1 3159258 R 224308 CDS NP_390968.1 16080142 936628 complement(3159691..3160746) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 7545510, 9603889; Product type cp: cell process; spore coat protein S 3160746 cotS 936628 cotS Bacillus subtilis subsp. subtilis str. 168 spore coat protein S NP_390968.1 3159691 R 224308 CDS NP_390969.1 16080143 936379 complement(3160761..3161894) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10234840, 11737650, 9603889; Product type cp: cell process; spore coat protein SA 3161894 cotSA 936379 cotSA Bacillus subtilis subsp. subtilis str. 168 spore coat protein SA NP_390969.1 3160761 R 224308 CDS NP_390970.1 16080144 936682 3162084..3163157 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor; spore coat protein I 3163157 cotI 936682 cotI Bacillus subtilis subsp. subtilis str. 168 spore coat protein I NP_390970.1 3162084 D 224308 CDS NP_390971.1 16080145 938164 3163237..3163704 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type prc: receptor; membrane protein 3163704 ytaB 938164 ytaB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390971.1 3163237 D 224308 CDS NP_390972.1 16080146 936630 complement(3163735..3166131) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15272305, 8145641; Product type e: enzyme; glycogen phosphorylase 3166131 glgP 936630 glgP Bacillus subtilis subsp. subtilis str. 168 glycogen phosphorylase NP_390972.1 3163735 R 224308 CDS NP_390973.1 16080147 936781 complement(3166118..3167572) 1 NC_000964.3 catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase 3167572 glgA 936781 glgA Bacillus subtilis subsp. subtilis str. 168 glycogen synthase NP_390973.1 3166118 R 224308 CDS NP_390974.1 16080148 936778 complement(3167569..3168600) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8145641, 9244254; Product type e: enzyme; glycogen biosynthesis protein GlgD 3168600 glgD 936778 glgD Bacillus subtilis subsp. subtilis str. 168 glycogen biosynthesis protein GlgD NP_390974.1 3167569 R 224308 CDS NP_390975.1 16080149 937990 complement(3168624..3169766) 1 NC_000964.3 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase 3169766 glgC 937990 glgC Bacillus subtilis subsp. subtilis str. 168 glucose-1-phosphate adenylyltransferase NP_390975.1 3168624 R 224308 CDS NP_390976.1 16080150 937993 complement(3169763..3171646) 1 NC_000964.3 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; 1,4-alpha-glucan branching enzyme GlgB 3171646 glgB 937993 glgB Bacillus subtilis subsp. subtilis str. 168 1,4-alpha-glucan branching enzyme GlgB NP_390976.1 3169763 R 224308 CDS NP_390977.1 16080151 937137 3179306..3179884 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16291685, 16356850, 16850406; Product type t: transporter; thiamine transporter ThiT 3179884 thiT 937137 thiT Bacillus subtilis subsp. subtilis str. 168 thiamine transporter ThiT NP_390977.1 3179306 D 224308 CDS NP_390978.1 16080152 938830 complement(3179926..3180447) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YuaI 3180447 yuaI 938830 yuaI Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YuaI NP_390978.1 3179926 R 224308 CDS NP_390979.1 16080153 937138 complement(3180465..3181994) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 17482313, 9153235, 9987136; Product type pf: factor; hypothetical protein 3181994 yuaG 937138 yuaG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390979.1 3180465 R 224308 CDS NP_390980.1 16080154 937144 complement(3182015..3182539) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12533473, 15849754, 16850406, 18696230; Product type pm: membrane component; membrane protein 3182539 yuaF 937144 yuaF Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390980.1 3182015 R 224308 CDS NP_390981.1 16080155 937143 3182707..3183195 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3183195 yuaE 937143 yuaE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390981.1 3182707 D 224308 CDS NP_390982.1 16080156 937141 complement(3183201..3183779) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11886751; metal-sulfur cluster biosynthesis proteins YuaD 3183779 yuaD 937141 yuaD Bacillus subtilis subsp. subtilis str. 168 metal-sulfur cluster biosynthesis proteins YuaD NP_390982.1 3183201 R 224308 CDS NP_390983.2 255767703 938832 complement(3183867..3185075) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8752328; Product type e: enzyme; alcohol dehydrogenase 3185075 gbsB 938832 gbsB Bacillus subtilis subsp. subtilis str. 168 alcohol dehydrogenase NP_390983.2 3183867 R 224308 CDS NP_390984.1 16080158 938829 complement(3185092..3186564) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8752328, 9297465; Product type e: enzyme; betaine aldehyde dehydrogenase 3186564 gbsA 938829 gbsA Bacillus subtilis subsp. subtilis str. 168 betaine aldehyde dehydrogenase NP_390984.1 3185092 R 224308 CDS NP_390985.1 16080159 938843 3186763..3187305 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8752328; Product type pr : regulator; hypothetical protein 3187305 yuaC 938843 yuaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390985.1 3186763 D 224308 CDS NP_390986.1 16080160 938831 3187503..3188048 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3188048 yuaB 938831 yuaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390986.1 3187503 D 224308 CDS NP_390987.1 16080161 937145 3188414..3189082 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624; Product type t: transporter; ktr system potassium uptake protein A 3189082 ktrA 937145 ktrA Bacillus subtilis subsp. subtilis str. 168 ktr system potassium uptake protein A NP_390987.1 3188414 D 224308 CDS NP_390988.1 16080162 938835 3189089..3190426 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562800, 15096624, 15849754, 16850406, 17932047; Product type t : transporter; ktr system potassium uptake protein B 3190426 ktrB 938835 ktrB Bacillus subtilis subsp. subtilis str. 168 ktr system potassium uptake protein B NP_390988.1 3189089 D 224308 CDS NP_390989.1 16080163 937150 complement(3190462..3190725) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3190725 yubF 937150 yubF Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_390989.1 3190462 R 224308 CDS NP_390990.1 16080164 937146 complement(3190834..3191682) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12525152, 16855244; Product type e: enzyme; exo-glucosaminidase LytG 3191682 lytG 937146 lytG Bacillus subtilis subsp. subtilis str. 168 exo-glucosaminidase LytG NP_390990.1 3190834 R 224308 CDS NP_390991.1 16080165 938834 complement(3191843..3193378) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3193378 yubD 938834 yubD Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_390991.1 3191843 R 224308 CDS NP_390992.1 16080166 938837 3193863..3194348 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10939241, 15699190, 16855246; Product type e: enzyme; cysteine dioxygenase 3194348 cdoA 938837 cdoA Bacillus subtilis subsp. subtilis str. 168 cysteine dioxygenase NP_390992.1 3193863 D 224308 CDS NP_390993.1 16080167 937148 complement(3194635..3195465) 1 NC_000964.3 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl-diphosphatase 3195465 yubB 937148 yubB Bacillus subtilis subsp. subtilis str. 168 undecaprenyl-diphosphatase NP_390993.1 3194635 R 224308 CDS NP_390994.1 16080168 938833 complement(3195558..3196724) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3196724 yubA 938833 yubA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_390994.1 3195558 R 224308 CDS NP_390995.1 16080169 937153 3196906..3197892 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12450853; Product type ph: phenotype; oxidoreductase 3197892 yulF 937153 yulF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_390995.1 3196906 D 224308 CDS NP_390996.1 16080170 938836 complement(3197933..3199207) 1 NC_000964.3 catalyzes the formation of L-rhamnulose from L-rhamnose; L-rhamnose isomerase 3199207 yulE 938836 yulE Bacillus subtilis subsp. subtilis str. 168 L-rhamnose isomerase NP_390996.1 3197933 R 224308 CDS NP_390997.1 16080171 937151 complement(3199233..3199547) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15876375; Product type e: enzyme; L-rhamnose mutarotase 3199547 yulD 937151 yulD Bacillus subtilis subsp. subtilis str. 168 L-rhamnose mutarotase NP_390997.1 3199233 R 224308 CDS NP_390998.1 16080172 938839 complement(3199565..3201022) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16674975; Product type e: enzyme; rhamnulokinase 3201022 yulC 938839 yulC Bacillus subtilis subsp. subtilis str. 168 rhamnulokinase NP_390998.1 3199565 R 224308 CDS NP_390999.1 16080173 938838 complement(3201027..3201803) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11496004; Product type pr : regulator; DeoR family transcriptional regulator 3201803 yulB 938838 yulB Bacillus subtilis subsp. subtilis str. 168 DeoR family transcriptional regulator NP_390999.1 3201027 R 224308 CDS NP_391000.1 16080174 938841 complement(3201860..3203929) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 3203929 yuxG 938841 yuxG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391000.1 3201860 R 224308 CDS NP_391001.1 16080175 937152 complement(3204067..3206055) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor; methyl-accepting chemotaxis protein TlpB 3206055 tlpB 937152 tlpB Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein TlpB NP_391001.1 3204067 R 224308 CDS NP_391002.2 255767704 937154 complement(3206169..3208154) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 8188684, 9721285; Product type rc : receptor; methyl-accepting chemotaxis protein McpA 3208154 mcpA 937154 mcpA Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein McpA NP_391002.2 3206169 R 224308 CDS NP_391003.1 16080177 938840 complement(3208280..3210268) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825179, 14563871, 8188684; Product type rc: receptor; methyl-accepting chemotaxis protein TlpA 3210268 tlpA 938840 tlpA Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein TlpA NP_391003.1 3208280 R 224308 CDS NP_391004.2 255767705 937155 complement(3210445..3212433) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12011078, 14731274, 15317802, 15544802; Product type rc: receptor; methyl-accepting chemotaxis protein McpB 3212433 mcpB 937155 mcpB Bacillus subtilis subsp. subtilis str. 168 methyl-accepting chemotaxis protein McpB NP_391004.2 3210445 R 224308 CDS NP_391005.1 16080179 937158 3212591..3213328 1 NC_000964.3 involved in assembly of spore coat proteins such as GerQ by catalyzing epsilon-(gamma-glutamyl)lysine cross links; protein-glutamine gamma-glutamyltransferase 3213328 tgl 937158 tgl Bacillus subtilis subsp. subtilis str. 168 protein-glutamine gamma-glutamyltransferase NP_391005.1 3212591 D 224308 CDS YP_003097776.1 255767706 8303174 complement(3213342..3213596) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3213596 yuzH 8303174 yuzH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097776.1 3213342 R 224308 CDS NP_391006.2 255767707 937156 complement(3213854..3214252) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3214252 yugU 937156 yugU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391006.2 3213854 R 224308 CDS NP_391007.2 255767708 938857 complement(3214372..3216036) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1761534; Product type pe : enzyme; oligo-1,6-glucosidase 3 3216036 yugT 938857 yugT Bacillus subtilis subsp. subtilis str. 168 oligo-1,6-glucosidase 3 NP_391007.2 3214372 R 224308 CDS NP_391008.2 255767709 937160 complement(3216163..3217452) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; hypothetical protein 3217452 yugS 937160 yugS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391008.2 3216163 R 224308 CDS NP_391009.1 16080183 938850 complement(3217496..3218173) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16704729, 16850406; Product type pe: enzyme; membrane protease YugP 3218173 yugP 938850 yugP Bacillus subtilis subsp. subtilis str. 168 membrane protease YugP NP_391009.1 3217496 R 224308 CDS YP_003097777.1 255767710 8303062 complement(3218215..3218478) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16704729; Product type f : factor; membrane protein 3218478 yuzI 8303062 yuzI Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097777.1 3218215 R 224308 CDS YP_003097778.1 255767711 8303011 3218525..3218857 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15731457; Product type m: membrane component; protein mistic 3218857 mstX 8303011 mstX Bacillus subtilis subsp. subtilis str. 168 protein mistic YP_003097778.1 3218525 D 224308 CDS NP_391010.3 255767712 938842 3218854..3219840 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16704729; Product type pt : transporter; potassium channel protein YugO 3219840 yugO 938842 yugO Bacillus subtilis subsp. subtilis str. 168 potassium channel protein YugO NP_391010.3 3218854 D 224308 CDS NP_391011.1 16080185 938845 complement(3219837..3220241) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3220241 yugN 938845 yugN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391011.1 3219837 R 224308 CDS NP_391012.1 16080186 937159 complement(3220301..3220672) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 3220672 yugM 937159 yugM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391012.1 3220301 R 224308 CDS NP_391013.2 255767713 937165 complement(3220731..3222083) 1 NC_000964.3 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase 3222083 pgi 937165 pgi Bacillus subtilis subsp. subtilis str. 168 glucose-6-phosphate isomerase NP_391013.2 3220731 R 224308 CDS NP_391014.1 16080188 938844 complement(3222195..3223367) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NADH-dependent butanol dehydrogenase 2 3223367 yugK 938844 yugK Bacillus subtilis subsp. subtilis str. 168 NADH-dependent butanol dehydrogenase 2 NP_391014.1 3222195 R 224308 CDS NP_391015.1 16080189 937164 complement(3223471..3224634) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317791, 9643546; Product type pe: enzyme; NADH-dependent butanol dehydrogenase 1 3224634 yugJ 937164 yugJ Bacillus subtilis subsp. subtilis str. 168 NADH-dependent butanol dehydrogenase 1 NP_391015.1 3223471 R 224308 CDS NP_391016.1 16080190 937163 3224864..3225100 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3225100 yuzA 937163 yuzA Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391016.1 3224864 D 224308 CDS NP_391017.1 16080191 938849 complement(3225178..3225570) 1 NC_000964.3 induced by heat shock, salt stress, oxidative stress, glucose limitation and oxygen limitation; general stress protein 13 3225570 yugI 938849 yugI Bacillus subtilis subsp. subtilis str. 168 general stress protein 13 NP_391017.1 3225178 R 224308 CDS NP_391018.2 50812284 938846 complement(3225772..3226932) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12670965; Product type pe : enzyme; aminotransferase YugH 3226932 alaT 938846 alaT Bacillus subtilis subsp. subtilis str. 168 aminotransferase YugH NP_391018.2 3225772 R 224308 CDS NP_391019.1 16080193 937166 complement(3226933..3227433) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; AsnC family transcriptional regulator 3227433 yugG 937166 yugG Bacillus subtilis subsp. subtilis str. 168 AsnC family transcriptional regulator NP_391019.1 3226933 R 224308 CDS NP_391020.1 16080194 937169 3227581..3228402 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hydrolase 3228402 yugF 937169 yugF Bacillus subtilis subsp. subtilis str. 168 hydrolase NP_391020.1 3227581 D 224308 CDS NP_391021.2 255767714 938847 complement(3228431..3228691) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3228691 yugE 938847 yugE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391021.2 3228431 R 224308 CDS NP_391022.1 16080196 937170 3228778..3229941 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15760717; Product type e: enzyme; cystathionine beta-lyase 3229941 patB 937170 patB Bacillus subtilis subsp. subtilis str. 168 cystathionine beta-lyase NP_391022.1 3228778 D 224308 CDS NP_391023.2 255767715 937167 3230067..3231353 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 11069677, 15849754, 16850406, 9426145; Product type e: enzyme; sporulation kinase B 3231353 kinB 937167 kinB Bacillus subtilis subsp. subtilis str. 168 sporulation kinase B NP_391023.2 3230067 D 224308 CDS NP_391024.1 16080198 938848 3231399..3231785 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9426145; Product type f : factor; kinase-associated lipoprotein B 3231785 kapB 938848 kapB Bacillus subtilis subsp. subtilis str. 168 kinase-associated lipoprotein B NP_391024.1 3231399 D 224308 CDS NP_391025.1 16080199 937171 complement(3231812..3232429) 1 NC_000964.3 inhibitor of the KinA pathway of sporulation; 3'-5' exonuclease KapD 3232429 kapD 937171 kapD Bacillus subtilis subsp. subtilis str. 168 3'-5' exonuclease KapD NP_391025.1 3231812 R 224308 CDS NP_391026.2 50812285 938852 3232640..3233818 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3233818 yuxJ 938852 yuxJ Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391026.2 3232640 D 224308 CDS NP_391027.2 255767716 938851 3233911..3235785 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 7961491, 9274030; Product type e: enzyme; penicillin-binding protein 4 3235785 pbpD 938851 pbpD Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 4 NP_391027.2 3233911 D 224308 CDS NP_391028.1 16080202 938854 3235806..3236219 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3236219 yuxK 938854 yuxK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391028.1 3235806 D 224308 CDS NP_391029.2 255767717 938853 complement(3236422..3236979) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3236979 yufK 938853 yufK Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391029.2 3236422 R 224308 CDS NP_391030.1 16080204 937173 3237157..3238758 1 NC_000964.3 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration; sensor histidine kinase 3238758 yufL 937173 yufL Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391030.1 3237157 D 224308 CDS NP_391031.1 16080205 937174 3238751..3239458 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12949159; Product type r: regulator; transcriptional regulatory protein MalR 3239458 yufM 937174 yufM Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein MalR NP_391031.1 3238751 D 224308 CDS NP_391032.2 255767718 938870 3239930..3241009 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3241009 yufN 938870 yufN Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_391032.2 3239930 D 224308 CDS NP_391033.1 16080207 937172 3241085..3242617 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3242617 yufO 937172 yufO Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391033.1 3241085 D 224308 CDS NP_391034.1 16080208 937175 3242610..3243656 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3243656 yufP 937175 yufP Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391034.1 3242610 D 224308 CDS NP_391035.1 16080209 937176 3243657..3244616 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3244616 yufQ 937176 yufQ Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391035.1 3243657 D 224308 CDS NP_391036.1 16080210 938855 3244770..3246116 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11004162, 12949159, 15849754, 16850406; Product type t: transporter; Na(+)-malate symporter 3246116 maeN 938855 maeN Bacillus subtilis subsp. subtilis str. 168 Na(+)-malate symporter NP_391036.1 3244770 D 224308 CDS NP_391037.1 16080211 938856 complement(3246152..3246367) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; hypothetical protein 3246367 yufS 938856 yufS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391037.1 3246152 R 224308 CDS NP_391038.2 161511068 938828 3246598..3249003 1 NC_000964.3 subunit A of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit A 3249003 mrpA 938828 mrpA Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit A NP_391038.2 3246598 D 224308 CDS NP_391039.1 16080213 937177 3248996..3249427 1 NC_000964.3 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in the case of S. meliloti it was proved to be involved specifically with K+ transport; Na(+)/H(+) antiporter subunit B 3249427 mrpB 937177 mrpB Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit B NP_391039.1 3248996 D 224308 CDS NP_391040.2 255767719 937139 3249427..3249768 1 NC_000964.3 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit C 3249768 mrpC 937139 mrpC Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit C NP_391040.2 3249427 D 224308 CDS NP_391041.3 255767720 938858 3249761..3251242 1 NC_000964.3 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; Na(+)/H(+) antiporter subunit D 3251242 mrpD 938858 mrpD Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit D NP_391041.3 3249761 D 224308 CDS YP_054591.2 255767721 2914191 3251248..3251724 1 NC_000964.3 subunit E of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit E 3251724 mrpE 2914191 mrpE Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit E YP_054591.2 3251248 D 224308 CDS NP_391043.2 255767722 938862 3251724..3252008 1 NC_000964.3 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; Na(+)/H(+) antiporter subunit F 3252008 mrpF 938862 mrpF Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit F NP_391043.2 3251724 D 224308 CDS NP_391044.1 16080217 938864 3251992..3252366 1 NC_000964.3 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; in S. meliloti it is known to be involved specifically with K+ transport; Na(+)/H(+) antiporter subunit G 3252366 mrpG 938864 mrpG Bacillus subtilis subsp. subtilis str. 168 Na(+)/H(+) antiporter subunit G NP_391044.1 3251992 D 224308 CDS NP_391045.2 255767723 937178 complement(3252405..3252785) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; esterase ComA2 3252785 yuxO 937178 yuxO Bacillus subtilis subsp. subtilis str. 168 esterase ComA2 NP_391045.2 3252405 R 224308 CDS NP_391046.1 16080219 937179 complement(3252804..3253448) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972833, 11179649, 11717295, 12950917, 16816200; Product type r: regulator; transcriptional regulatory protein ComA 3253448 comA 937179 comA Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein ComA NP_391046.1 3252804 R 224308 CDS NP_391047.2 255767724 938866 complement(3253529..3255838) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10419951, 14679219, 15066026, 16091050, 16787201, 7698645, 7855425; Product type rc: receptor; sensor histidine kinase 3255838 comP 938866 comP Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391047.2 3253529 R 224308 CDS NP_391048.1 16080221 938875 complement(3255853..3256020) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141, 18323630; Product type f : factor; competence pheromone 3256020 comX 938875 comX Bacillus subtilis subsp. subtilis str. 168 competence pheromone NP_391048.1 3255853 R 224308 CDS NP_391049.2 255767725 937180 complement(3256008..3256907) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11751817, 12067344, 14679219, 16407988, 17240141; Product type e: enzyme; competence regulatory protein ComQ 3256907 comQ 937180 comQ Bacillus subtilis subsp. subtilis str. 168 competence regulatory protein ComQ NP_391049.2 3256008 R 224308 CDS NP_391050.1 16080223 936547 complement(3257092..3257232) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16251307, 16942812, 1901055; Product type r: regulator; degradation enzyme regulation protein DegQ 3257232 degQ 936547 degQ Bacillus subtilis subsp. subtilis str. 168 degradation enzyme regulation protein DegQ NP_391050.1 3257092 R 224308 CDS NP_391051.2 255767726 938859 3257693..3258061 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 16321932; Product type cp: cell process; hypothetical protein 3258061 yuzC 938859 yuzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391051.2 3257693 D 224308 CDS NP_391052.1 16080225 937185 complement(3258037..3259266) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17153922; Product type pe : enzyme; phosphodiesterase 3259266 pdeH 937185 pdeH Bacillus subtilis subsp. subtilis str. 168 phosphodiesterase NP_391052.1 3258037 R 224308 CDS NP_391053.1 16080226 937186 complement(3259403..3260875) 1 NC_000964.3 catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase 3260875 yueK 937186 yueK Bacillus subtilis subsp. subtilis str. 168 nicotinate phosphoribosyltransferase NP_391053.1 3259403 R 224308 CDS NP_391054.1 16080227 938863 complement(3260891..3261442) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15135535, 17382284; Product type e: enzyme; isochorismatase 3261442 pncA 938863 pncA Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_391054.1 3260891 R 224308 CDS NP_391055.1 16080228 938125 complement(3261539..3261937) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3261937 yueI 938125 yueI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391055.1 3261539 R 224308 CDS NP_391056.1 16080229 936537 complement(3262009..3262257) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3262257 yueH 936537 yueH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391056.1 3262009 R 224308 CDS NP_391057.1 16080230 936561 complement(3262330..3262551) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; spore germination protein-like protein YueG 3262551 yueG 936561 yueG Bacillus subtilis subsp. subtilis str. 168 spore germination protein-like protein YueG NP_391057.1 3262330 R 224308 CDS NP_391058.1 16080231 936534 complement(3262611..3263720) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10960106, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3263720 yueF 936534 yueF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391058.1 3262611 R 224308 CDS NP_391059.1 16080232 937187 3263835..3264224 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3264224 yuzE 937187 yuzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391059.1 3263835 D 224308 CDS NP_391060.1 16080233 936562 complement(3264265..3264501) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3264501 yuzF 936562 yuzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391060.1 3264265 R 224308 CDS NP_391061.1 16080234 936545 complement(3264678..3265208) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphohydrolase YueE 3265208 yueE 936545 yueE Bacillus subtilis subsp. subtilis str. 168 phosphohydrolase YueE NP_391061.1 3264678 R 224308 CDS NP_391062.1 16080235 936558 complement(3265406..3266137) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11745140; Product type pe : enzyme; benzil reductase 3266137 yueD 936558 yueD Bacillus subtilis subsp. subtilis str. 168 benzil reductase NP_391062.1 3265406 R 224308 CDS NP_391063.1 16080236 936550 complement(3266200..3266655) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 15576783; hypothetical protein 3266655 yueC 936550 yueC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391063.1 3266200 R 224308 CDS NP_391064.1 16080237 936567 complement(3266687..3269917) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15576783; Product type ph: phenotype; bacteriophage SPP1 adsorption protein YueB 3269917 yueB 936567 yueB Bacillus subtilis subsp. subtilis str. 168 bacteriophage SPP1 adsorption protein YueB NP_391064.1 3266687 R 224308 CDS NP_391066.2 255767727 936565 complement(3269914..3274401) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783; Product type pf : factor; Ftsk domain-containing protein YukB 3274401 yukB 936565 yukB Bacillus subtilis subsp. subtilis str. 168 Ftsk domain-containing protein YukB NP_391066.2 3269914 R 224308 CDS NP_391067.1 16080240 936572 complement(3274462..3275817) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pe: enzyme; hypothetical protein 3275817 yukC 936572 yukC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391067.1 3274462 R 224308 CDS NP_391068.1 16080241 936543 complement(3275832..3276071) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15576783, 16845009; Product type pf: factor; ubiquitin-like protein YukD 3276071 yukD 936543 yukD Bacillus subtilis subsp. subtilis str. 168 ubiquitin-like protein YukD NP_391068.1 3275832 R 224308 CDS NP_391069.2 255767728 936578 complement(3276141..3276434) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783; hypothetical protein 3276434 yukE 936578 yukE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391069.2 3276141 R 224308 CDS NP_391070.2 255767729 938860 3276955..3278223 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator 3278223 yukF 938860 yukF Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391070.2 3276955 D 224308 CDS NP_391071.1 16080244 936557 3278325..3279461 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 8226620; Product type e : enzyme; alanine dehydrogenase 3279461 ald 936557 ald Bacillus subtilis subsp. subtilis str. 168 alanine dehydrogenase NP_391071.1 3278325 D 224308 CDS NP_391073.2 255767730 937111 3279573..3280250 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3280250 yukJ 937111 yukJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391073.2 3279573 D 224308 CDS YP_003097779.1 255767731 8303138 complement(3280294..3280503) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11112781; hypothetical protein 3280503 ybdZ 8303138 ybdZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097779.1 3280294 R 224308 CDS NP_391076.3 255767732 936569 complement(3280519..3287655) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11112781, 12354229, 16672620; Product type e: enzyme; dimodular nonribosomal peptide synthase 3287655 dhbF 936569 dhbF Bacillus subtilis subsp. subtilis str. 168 dimodular nonribosomal peptide synthase NP_391076.3 3280519 R 224308 CDS NP_391077.1 16080250 936582 complement(3287675..3288613) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme; isochorismatase 3288613 dhbB 936582 dhbB Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_391077.1 3287675 R 224308 CDS NP_391078.1 16080251 936509 complement(3288641..3290260) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16672620, 9214294; Product type e : enzyme; 2,3-dihydroxybenzoate-AMP ligase 3290260 dhbE 936509 dhbE Bacillus subtilis subsp. subtilis str. 168 2,3-dihydroxybenzoate-AMP ligase NP_391078.1 3288641 R 224308 CDS NP_391079.2 255767733 937162 complement(3290289..3291485) 1 NC_000964.3 synthesizes isochorismate from chorismate as part of the biosynthesis of the siderophore 2,3-dihydroxybenzoate; can also be used in menaquinone synthesis; isochorismate synthase DhbC 3291485 dhbC 937162 dhbC Bacillus subtilis subsp. subtilis str. 168 isochorismate synthase DhbC NP_391079.2 3290289 R 224308 CDS NP_391080.2 255767734 936579 complement(3291511..3292296) 1 NC_000964.3 catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin; 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 3292296 dhbA 936579 dhbA Bacillus subtilis subsp. subtilis str. 168 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase NP_391080.2 3291511 R 224308 CDS NP_391081.2 255767735 936592 complement(3292490..3293359) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16889643; Product type e: enzyme; ferri-bacillibactin esterase BesA 3293359 besA 936592 besA Bacillus subtilis subsp. subtilis str. 168 ferri-bacillibactin esterase BesA NP_391081.2 3292490 R 224308 CDS NP_391082.1 16080255 937188 complement(3293573..3294169) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11598126, 16341843; Product type pe: enzyme; oxidoreductase 3294169 yuiH 937188 yuiH Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391082.1 3293573 R 224308 CDS NP_391083.1 16080256 936511 3294270..3294872 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11717296, 15849754, 16850406; Product type pt: transporter; biotin transporter BioYB 3294872 bioYB 936511 bioYB Bacillus subtilis subsp. subtilis str. 168 biotin transporter BioYB NP_391083.1 3294270 D 224308 CDS NP_391084.1 16080257 937212 complement(3294942..3296270) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15135544, 15849754, 16850406; Product type t: transporter; amino acid transporter YuiF 3296270 yuiF 937212 yuiF Bacillus subtilis subsp. subtilis str. 168 amino acid transporter YuiF NP_391084.1 3294942 R 224308 CDS NP_391085.1 16080258 936587 complement(3296417..3297919) 1 NC_000964.3 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; cytosol aminopeptidase 3297919 yuiE 936587 yuiE Bacillus subtilis subsp. subtilis str. 168 cytosol aminopeptidase NP_391085.1 3296417 R 224308 CDS NP_391086.1 16080259 936516 3298077..3298553 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3298553 yuiD 936516 yuiD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391086.1 3298077 D 224308 CDS NP_391087.1 16080260 936601 complement(3298584..3299240) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3299240 yuiC 936601 yuiC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391087.1 3298584 R 224308 CDS NP_391088.1 16080261 938035 complement(3299344..3299664) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3299664 yuiB 938035 yuiB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391088.1 3299344 R 224308 CDS NP_391089.1 16080262 938869 complement(3299718..3299861) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3299861 yuiA 938869 yuiA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391089.1 3299718 R 224308 CDS NP_391090.1 16080263 937062 complement(3300034..3301254) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154, 17015645; Product type pe: enzyme; NADH dehydrogenase-like protein YumB 3301254 yumB 937062 yumB Bacillus subtilis subsp. subtilis str. 168 NADH dehydrogenase-like protein YumB NP_391090.1 3300034 R 224308 CDS NP_391091.2 255767736 936577 3301586..3302584 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15252706; Product type e: enzyme; ferredoxin--NADP reductase 2 3302584 yumC 936577 yumC Bacillus subtilis subsp. subtilis str. 168 ferredoxin--NADP reductase 2 NP_391091.2 3301586 D 224308 CDS NP_391092.1 16080265 936597 complement(3302623..3302763) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3302763 yuzG 936597 yuzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391092.1 3302623 R 224308 CDS NP_391093.2 255767737 937189 3303042..3304022 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11591660, 6408059; Product type e: enzyme; GMP reductase 3304022 guaC 937189 guaC Bacillus subtilis subsp. subtilis str. 168 GMP reductase NP_391093.2 3303042 D 224308 CDS NP_391094.2 255767738 936588 complement(3304096..3304719) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16210326; Product type pe : enzyme; protease synthase and sporulation protein PAI 2 3304719 paiB 936588 paiB Bacillus subtilis subsp. subtilis str. 168 protease synthase and sporulation protein PAI 2 NP_391094.2 3304096 R 224308 CDS NP_391095.1 16080268 937204 complement(3304743..3305261) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16210326, 17588214; Product type e: enzyme; protease synthase and sporulation negative regulatory protein PAI 1 3305261 paiA 937204 paiA Bacillus subtilis subsp. subtilis str. 168 protease synthase and sporulation negative regulatory protein PAI 1 NP_391095.1 3304743 R 224308 CDS NP_391096.1 16080269 936627 complement(3305599..3305961) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3305961 yutM 936627 yutM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391096.1 3305599 R 224308 CDS NP_391097.1 16080270 937110 complement(3306040..3306894) 1 NC_000964.3 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate; diaminopimelate epimerase 3306894 dapF 937110 dapF Bacillus subtilis subsp. subtilis str. 168 diaminopimelate epimerase NP_391097.1 3306040 R 224308 CDS NP_391098.1 16080271 936517 complement(3307017..3308231) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3308231 yutK 936517 yutK Bacillus subtilis subsp. subtilis str. 168 transporter NP_391098.1 3307017 R 224308 CDS NP_391099.1 16080272 936585 complement(3308368..3308604) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3308604 yuzB 936585 yuzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391099.1 3308368 R 224308 CDS NP_391100.2 255767739 936600 3308867..3309934 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17015645; Product type pe : enzyme; NADH dehydrogenase-like protein YutJ 3309934 yutJ 936600 yutJ Bacillus subtilis subsp. subtilis str. 168 NADH dehydrogenase-like protein YutJ NP_391100.2 3308867 D 224308 CDS NP_391101.1 16080274 937202 complement(3309960..3310286) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11551182; Product type pe : enzyme; disulfide oxidoreductase YuzD 3310286 yuzD 937202 yuzD Bacillus subtilis subsp. subtilis str. 168 disulfide oxidoreductase YuzD NP_391101.1 3309960 R 224308 CDS NP_391102.1 16080275 936658 3310386..3310721 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17237162; Product type pf : factor; nitrogen fixation protein YutI 3310721 yutI 936658 yutI Bacillus subtilis subsp. subtilis str. 168 nitrogen fixation protein YutI NP_391102.1 3310386 D 224308 CDS NP_391103.2 255767740 936648 complement(3310763..3312736) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8576092; Product type pe : enzyme; peptidase YuxL 3312736 yuxL 936648 yuxL Bacillus subtilis subsp. subtilis str. 168 peptidase YuxL NP_391103.2 3310763 R 224308 CDS NP_391104.1 16080277 936665 complement(3312844..3313773) 1 NC_000964.3 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase 3313773 thrB 936665 thrB Bacillus subtilis subsp. subtilis str. 168 homoserine kinase NP_391104.1 3312844 R 224308 CDS NP_391105.1 16080278 936660 complement(3313770..3314828) 1 NC_000964.3 catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase 3314828 thrC 936660 thrC Bacillus subtilis subsp. subtilis str. 168 threonine synthase NP_391105.1 3313770 R 224308 CDS NP_391106.1 16080279 936654 complement(3314828..3316129) 1 NC_000964.3 catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase 3316129 hom 936654 hom Bacillus subtilis subsp. subtilis str. 168 homoserine dehydrogenase NP_391106.1 3314828 R 224308 CDS NP_391107.1 16080280 936635 complement(3316330..3317349) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231775; Product type cp: cell process; endospore coat-associated protein YutH 3317349 yutH 936635 yutH Bacillus subtilis subsp. subtilis str. 168 endospore coat-associated protein YutH NP_391107.1 3316330 R 224308 CDS NP_391108.1 16080281 936659 3317502..3318002 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3318002 yutG 936659 yutG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391108.1 3317502 D 224308 CDS NP_391109.1 16080282 936508 complement(3318029..3318799) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15664928, 16766528; Product type pe: enzyme; hydrolase YutF 3318799 yutF 936508 yutF Bacillus subtilis subsp. subtilis str. 168 hydrolase YutF NP_391109.1 3318029 R 224308 CDS NP_391110.1 16080283 938483 complement(3318828..3319262) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3319262 yutE 938483 yutE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391110.1 3318828 R 224308 CDS NP_391111.2 255767741 937182 complement(3319286..3319561) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717; hypothetical protein 3319561 yutD 937182 yutD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391111.2 3319286 R 224308 CDS NP_391112.1 16080285 936674 3319676..3320308 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3320308 yutC 936674 yutC Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_391112.1 3319676 D 224308 CDS NP_391113.2 50812289 938861 complement(3320324..3321220) 1 NC_000964.3 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 3321220 lipA 938861 lipA Bacillus subtilis subsp. subtilis str. 168 lipoyl synthase NP_391113.2 3320324 R 224308 CDS NP_391114.2 255767742 936510 3321455..3322435 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12813075; Product type cp: cell process; L-Ala--D-Glu endopeptidase 3322435 lytH 936510 lytH Bacillus subtilis subsp. subtilis str. 168 L-Ala--D-Glu endopeptidase NP_391114.2 3321455 D 224308 CDS NP_391115.1 16080288 936670 complement(3322463..3323227) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12662922; Product type cp : cell process; sporulation protein YunB 3323227 yunB 936670 yunB Bacillus subtilis subsp. subtilis str. 168 sporulation protein YunB NP_391115.1 3322463 R 224308 CDS NP_391116.1 16080289 936679 complement(3323300..3323605) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3323605 yunC 936679 yunC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391116.1 3323300 R 224308 CDS NP_391117.1 16080290 936666 complement(3323670..3325058) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase 3325058 yunD 936666 yunD Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_391117.1 3323670 R 224308 CDS NP_391118.1 16080291 936506 complement(3325078..3325899) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3325899 yunE 936506 yunE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391118.1 3325078 R 224308 CDS NP_391119.2 255767743 937089 complement(3325917..3326765) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3326765 yunF 937089 yunF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391119.2 3325917 R 224308 CDS NP_391120.1 16080293 936684 complement(3326803..3327150) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3327150 yunG 936684 yunG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391120.1 3326803 R 224308 CDS NP_391121.1 16080294 936662 complement(3327247..3328587) 1 NC_000964.3 Plays a crucial role on both purine and pyrimidine metabolism; allantoinase 3328587 pucH 936662 pucH Bacillus subtilis subsp. subtilis str. 168 allantoinase NP_391121.1 3327247 R 224308 CDS NP_391122.1 16080295 937221 3328762..3330357 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 12374841; Product type r: regulator; purine catabolism regulatory protein 3330357 pucR 937221 pucR Bacillus subtilis subsp. subtilis str. 168 purine catabolism regulatory protein NP_391122.1 3328762 D 224308 CDS NP_391123.1 16080296 937096 3330502..3331851 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter; uric acid permease PucJ 3331851 pucJ 937096 pucJ Bacillus subtilis subsp. subtilis str. 168 uric acid permease PucJ NP_391123.1 3330502 D 224308 CDS NP_391124.1 16080297 937191 3331857..3333149 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 15849754, 16850406; Product type t: transporter; uric acid permease PucK 3333149 pucK 937191 pucK Bacillus subtilis subsp. subtilis str. 168 uric acid permease PucK NP_391124.1 3331857 D 224308 CDS NP_391125.1 16080298 936669 3333162..3334646 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; urate oxidase with peroxide reductase N-terminal domain 3334646 pucL 936669 pucL Bacillus subtilis subsp. subtilis str. 168 urate oxidase with peroxide reductase N-terminal domain NP_391125.1 3333162 D 224308 CDS NP_391126.2 255767744 937977 3334646..3334990 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11344136; Product type s: structure; 5-hydroxyisourate hydrolase 3334990 pucM 937977 pucM Bacillus subtilis subsp. subtilis str. 168 5-hydroxyisourate hydrolase NP_391126.2 3334646 D 224308 CDS YP_003097780.1 255767745 8303056 3335414..3335545 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3335545 yuzJ 8303056 yuzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097780.1 3335414 D 224308 CDS NP_391127.1 16080300 936680 complement(3335751..3336272) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit E 3336272 pucE 936680 pucE Bacillus subtilis subsp. subtilis str. 168 xanthine dehydrogenase subunit E NP_391127.1 3335751 R 224308 CDS NP_391128.1 16080301 936686 complement(3336263..3338500) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit D 3338500 pucD 936686 pucD Bacillus subtilis subsp. subtilis str. 168 xanthine dehydrogenase subunit D NP_391128.1 3336263 R 224308 CDS NP_391129.1 16080302 936685 complement(3338501..3339334) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; xanthine dehydrogenase subunit C 3339334 pucC 936685 pucC Bacillus subtilis subsp. subtilis str. 168 xanthine dehydrogenase subunit C NP_391129.1 3338501 R 224308 CDS NP_391130.2 255767746 936486 complement(3339331..3339948) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type e: enzyme; purine catabolism protein PucB 3339948 pucB 936486 pucB Bacillus subtilis subsp. subtilis str. 168 purine catabolism protein PucB NP_391130.2 3339331 R 224308 CDS NP_391131.1 16080304 938865 complement(3339945..3340937) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136; Product type c: carrier; xanthine dehydrogenase subunit A 3340937 pucA 938865 pucA Bacillus subtilis subsp. subtilis str. 168 xanthine dehydrogenase subunit A NP_391131.1 3339945 R 224308 CDS NP_391132.1 16080305 936676 complement(3341166..3342416) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11344136; Product type pe : enzyme; purine catabolism protein PucG 3342416 pucG 936676 pucG Bacillus subtilis subsp. subtilis str. 168 purine catabolism protein PucG NP_391132.1 3341166 R 224308 CDS NP_391133.1 16080306 936699 complement(3342433..3343671) 1 NC_000964.3 allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide; allantoate amidohydrolase 3343671 yurH 936699 yurH Bacillus subtilis subsp. subtilis str. 168 allantoate amidohydrolase NP_391133.1 3342433 R 224308 CDS NP_391134.1 16080307 936687 3344113..3344979 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12490701, 16291680; Product type e: enzyme; extracellular ribonuclease 3344979 bsn 936687 bsn Bacillus subtilis subsp. subtilis str. 168 extracellular ribonuclease NP_391134.1 3344113 D 224308 CDS NP_391135.1 16080308 937070 complement(3345013..3346116) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3346116 yurJ 937070 yurJ Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391135.1 3345013 R 224308 CDS NP_391136.2 161511067 936688 3346238..3347026 1 NC_000964.3 may act as a transcriptional regulator of a fructoselysine-induced operon containing the yhfM, yhfN, yhfO, yhfP, yhfQ, and yhfR genes; DNA-binding transcriptional regulator FrlR 3347026 frlR 936688 frlR Bacillus subtilis subsp. subtilis str. 168 DNA-binding transcriptional regulator FrlR NP_391136.2 3346238 D 224308 CDS NP_391137.1 16080310 936704 complement(3347051..3347905) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14641112, 16153181; Product type e: enzyme; fructosamine kinase FrlD 3347905 frlD 936704 frlD Bacillus subtilis subsp. subtilis str. 168 fructosamine kinase FrlD NP_391137.1 3347051 R 224308 CDS NP_391138.1 16080311 936696 complement(3347919..3348821) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3348821 frlM 936696 frlM Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391138.1 3347919 R 224308 CDS NP_391139.1 16080312 936689 complement(3348825..3349703) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3349703 frlN 936689 frlN Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391139.1 3348825 R 224308 CDS NP_391140.1 16080313 937094 complement(3349761..3351029) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12618455; Product type pt : transporter; ABC transporter extracellular-binding protein YurO 3351029 frlO 937094 frlO Bacillus subtilis subsp. subtilis str. 168 ABC transporter extracellular-binding protein YurO NP_391140.1 3349761 R 224308 CDS NP_391141.1 16080314 936701 complement(3351110..3352096) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12618455, 16153181; Product type e: enzyme; fructosamine deglycase FrlB 3352096 frlB 936701 frlB Bacillus subtilis subsp. subtilis str. 168 fructosamine deglycase FrlB NP_391141.1 3351110 R 224308 CDS NP_391142.1 16080315 936694 complement(3352312..3352686) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3352686 yurQ 936694 yurQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391142.1 3352312 R 224308 CDS NP_391143.1 16080316 937069 complement(3352789..3353907) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 3353907 yurR 937069 yurR Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391143.1 3352789 R 224308 CDS YP_054592.1 50812290 2914218 3354066..3354212 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type f : factor; small acid-soluble spore protein G 3354212 sspG 2914218 sspG Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein G YP_054592.1 3354066 D 224308 CDS NP_391144.1 16080317 936705 3354212..3354487 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 9852018; hypothetical protein 3354487 yurS 936705 yurS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391144.1 3354212 D 224308 CDS NP_391145.1 16080318 937193 complement(3354551..3354934) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10882093; Product type pe : enzyme; hypothetical protein 3354934 yurT 937193 yurT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391145.1 3354551 R 224308 CDS YP_003097781.1 255767747 8303129 complement(3355045..3355323) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YuzN 3355323 yuzN 8303129 yuzN Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YuzN YP_003097781.1 3355045 R 224308 CDS NP_391146.1 16080319 936706 complement(3355593..3356990) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor; FeS cluster assembly protein SufB 3356990 sufB 936706 sufB Bacillus subtilis subsp. subtilis str. 168 FeS cluster assembly protein SufB NP_391146.1 3355593 R 224308 CDS NP_391147.1 16080320 936702 complement(3357011..3357454) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16877383; Product type f : factor; NifU-like protein 3357454 iscU 936702 iscU Bacillus subtilis subsp. subtilis str. 168 NifU-like protein NP_391147.1 3357011 R 224308 CDS NP_391148.1 16080321 937108 complement(3357444..3358664) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 12876288, 14644425, 15901727; Product type e: enzyme; cysteine desulfurase 3358664 sufS 937108 sufS Bacillus subtilis subsp. subtilis str. 168 cysteine desulfurase NP_391148.1 3357444 R 224308 CDS NP_391149.1 16080322 938871 complement(3358664..3359977) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16109955, 16431905, 16621837; Product type f: factor; FeS cluster assembly protein SufD 3359977 sufD 938871 sufD Bacillus subtilis subsp. subtilis str. 168 FeS cluster assembly protein SufD NP_391149.1 3358664 R 224308 CDS NP_391150.1 16080323 937073 complement(3359995..3360780) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12682299, 16431905; Product type e : enzyme; vegetative protein 296 3360780 sufC 937073 sufC Bacillus subtilis subsp. subtilis str. 168 vegetative protein 296 NP_391150.1 3359995 R 224308 CDS YP_003097782.1 255767748 8303161 complement(3360974..3361111) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3361111 yuzK 8303161 yuzK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097782.1 3360974 R 224308 CDS NP_391151.1 16080324 937080 complement(3361305..3361682) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3361682 yurZ 937080 yurZ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391151.1 3361305 R 224308 CDS NP_391152.1 16080325 936716 complement(3361767..3362591) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter; methionine-binding lipoprotein MetQ 3362591 metN 936716 metN Bacillus subtilis subsp. subtilis str. 168 methionine-binding lipoprotein MetQ NP_391152.1 3361767 R 224308 CDS NP_391153.1 16080326 936709 complement(3362605..3363273) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 15849754, 16850406, 17038623, 10094622; Product type t : transporter; methionine import system permease protein MetP 3363273 metP 936709 metP Bacillus subtilis subsp. subtilis str. 168 methionine import system permease protein MetP NP_391153.1 3362605 R 224308 CDS NP_391154.1 16080327 936700 complement(3363266..3364291) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12910260, 14990259, 17038623, 10094622; Product type t: transporter; methionine import ATP-binding protein MetN 3364291 metQ 936700 metQ Bacillus subtilis subsp. subtilis str. 168 methionine import ATP-binding protein MetN NP_391154.1 3363266 R 224308 CDS NP_391155.1 16080328 936713 complement(3364618..3364962) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3364962 yusD 936713 yusD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391155.1 3364618 R 224308 CDS NP_391156.1 16080329 937184 complement(3365069..3365389) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; thioredoxin 3365389 yusE 937184 yusE Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_391156.1 3365069 R 224308 CDS NP_391157.1 16080330 936707 complement(3365391..3365831) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12794188; Product type pe : enzyme; hypothetical protein 3365831 yusF 936707 yusF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391157.1 3365391 R 224308 CDS NP_391158.1 16080331 936719 complement(3365831..3366067) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3366067 yusG 936719 yusG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391158.1 3365831 R 224308 CDS NP_391159.1 16080332 936724 complement(3366123..3366506) 1 NC_000964.3 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor; glycine cleavage system H protein 3366506 yusH 936724 yusH Bacillus subtilis subsp. subtilis str. 168 glycine cleavage system H protein NP_391159.1 3366123 R 224308 CDS NP_391160.1 16080333 936722 complement(3366573..3366929) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3366929 yusI 936722 yusI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391160.1 3366573 R 224308 CDS NP_391161.1 16080334 936717 complement(3367040..3368824) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; acyl-CoA dehydrogenase 3368824 fadE 936717 fadE Bacillus subtilis subsp. subtilis str. 168 acyl-CoA dehydrogenase NP_391161.1 3367040 R 224308 CDS NP_391162.1 16080335 936729 complement(3368839..3370014) 1 NC_000964.3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; 3-ketoacyl-CoA thiolase 3370014 yusK 936729 yusK Bacillus subtilis subsp. subtilis str. 168 3-ketoacyl-CoA thiolase NP_391162.1 3368839 R 224308 CDS NP_391163.1 16080336 937125 complement(3370025..3372472) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; enoyl-CoA hydratase 3372472 fadN 937125 fadN Bacillus subtilis subsp. subtilis str. 168 enoyl-CoA hydratase NP_391163.1 3370025 R 224308 CDS YP_003097783.1 255767749 8302982 3372569..3372715 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17189250; hypothetical protein 3372715 yuzL 8302982 yuzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097783.1 3372569 D 224308 CDS NP_391164.1 16080337 937064 complement(3372740..3373648) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; proline dehydrogenase 1 3373648 fadM 937064 fadM Bacillus subtilis subsp. subtilis str. 168 proline dehydrogenase 1 NP_391164.1 3372740 R 224308 CDS YP_003097784.1 255767750 8302981 3373743..3373988 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3373988 yuzM 8302981 yuzM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097784.1 3373743 D 224308 CDS NP_391165.1 16080338 937194 3374001..3374333 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3374333 yusN 937194 yusN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391165.1 3374001 D 224308 CDS NP_391166.1 16080339 935923 3374492..3374959 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12923086; Product type pr : regulator; HTH-type transcriptional regulator YusO 3374959 yusO 935923 yusO Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YusO NP_391166.1 3374492 D 224308 CDS NP_391167.1 16080340 937088 3374956..3376581 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3376581 yusP 937088 yusP Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391167.1 3374956 D 224308 CDS NP_391168.1 16080341 938468 complement(3376617..3377000) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; tautomerase YusQ 3377000 yusQ 938468 yusQ Bacillus subtilis subsp. subtilis str. 168 tautomerase YusQ NP_391168.1 3376617 R 224308 CDS NP_391169.1 16080342 937076 complement(3377019..3377408) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 3-oxoacyl-ACP reductase 3377408 yusR 937076 yusR Bacillus subtilis subsp. subtilis str. 168 3-oxoacyl-ACP reductase NP_391169.1 3377019 R 224308 CDS NP_391170.1 16080343 935924 complement(3377430..3377759) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; short-chain dehydrogenase/reductase homolog YusS 3377759 yusS 935924 yusS Bacillus subtilis subsp. subtilis str. 168 short-chain dehydrogenase/reductase homolog YusS NP_391170.1 3377430 R 224308 CDS NP_391171.1 16080344 938601 3377893..3378780 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YusT 3378780 yusT 938601 yusT Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YusT NP_391171.1 3377893 D 224308 CDS NP_391172.1 16080345 935925 complement(3378800..3379087) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3379087 yusU 935925 yusU Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391172.1 3378800 R 224308 CDS NP_391173.1 16080346 935921 complement(3379112..3379939) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620; Product type t: transporter; siderophore transport system ATP-binding protein YusV 3379939 yusV 935921 yusV Bacillus subtilis subsp. subtilis str. 168 siderophore transport system ATP-binding protein YusV NP_391173.1 3379112 R 224308 CDS NP_391174.1 16080347 938599 complement(3380157..3380594) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 3380594 yusW 938599 yusW Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391174.1 3380157 R 224308 CDS NP_391177.1 16080350 938596 3382633..3383475 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 3383475 yusZ 938596 yusZ Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391177.1 3382633 D 224308 CDS NP_391178.1 16080351 938592 3383565..3384026 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12029044, 8709848; Product type f: factor; metalloregulation DNA-binding stress protein 3384026 mrgA 938592 mrgA Bacillus subtilis subsp. subtilis str. 168 metalloregulation DNA-binding stress protein NP_391178.1 3383565 D 224308 CDS NP_391180.2 50812291 935935 complement(3384070..3385446) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11133960, 11717295, 16033468, 16911528; Product type e: enzyme; serine protease Do-like HtrB 3385446 htrB 935935 htrB Bacillus subtilis subsp. subtilis str. 168 serine protease Do-like HtrB NP_391180.2 3384070 R 224308 CDS NP_391181.1 16080354 938594 3385724..3386401 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type r: regulator; transcriptional regulatory protein CssR 3386401 cssR 938594 cssR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein CssR NP_391181.1 3385724 D 224308 CDS NP_391182.2 255767751 935936 3386398..3387753 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11555295, 11717295, 12270824, 15856219, 16911528; Product type rc: receptor; sensor histidine kinase 3387753 cssS 935936 cssS Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391182.2 3386398 D 224308 CDS YP_003097785.1 255767752 8303202 complement(3387781..3387945) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3387945 yuzO 8303202 yuzO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097785.1 3387781 R 224308 CDS NP_391183.1 16080356 935945 3388113..3388988 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YuxN 3388988 yuxN 935945 yuxN Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YuxN NP_391183.1 3388113 D 224308 CDS NP_391184.1 16080357 938591 complement(3389024..3390412) 1 NC_000964.3 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase class II 3390412 fumC 938591 fumC Bacillus subtilis subsp. subtilis str. 168 fumarate hydratase class II NP_391184.1 3389024 R 224308 CDS YP_003097786.1 255767753 8303152 complement(3390479..3390664) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3390664 yvzF 8303152 yvzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097786.1 3390479 R 224308 CDS NP_391185.2 255767754 935953 3390782..3392230 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process; spore germination protein A1 3392230 gerAA 935953 gerAA Bacillus subtilis subsp. subtilis str. 168 spore germination protein A1 NP_391185.2 3390782 D 224308 CDS NP_391186.1 16080359 935948 3392199..3393296 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16740944, 16850406; Product type cp: cell process; spore germination protein A2 3393296 gerAB 935948 gerAB Bacillus subtilis subsp. subtilis str. 168 spore germination protein A2 NP_391186.1 3392199 D 224308 CDS NP_391187.1 16080360 935951 3393293..3394414 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11418573, 15774895, 16740944; Product type cp: cell process; spore germination protein A3 3394414 gerAC 935951 gerAC Bacillus subtilis subsp. subtilis str. 168 spore germination protein A3 NP_391187.1 3393293 D 224308 CDS NP_391188.1 16080361 935957 complement(3394422..3395057) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type r: regulator; transcriptional regulatory protein LiaR 3395057 liaR 935957 liaR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein LiaR NP_391188.1 3394422 R 224308 CDS NP_391189.1 16080362 935967 complement(3395035..3396117) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15273097, 16816187; Product type rc: receptor; sensor histidine kinase 3396117 liaS 935967 liaS Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391189.1 3395035 R 224308 CDS NP_391190.1 16080363 938469 complement(3396114..3396839) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406, 17660417; Product type m: membrane component; LiaR negative effector LiaF 3396839 liaF 938469 liaF Bacillus subtilis subsp. subtilis str. 168 LiaR negative effector LiaF NP_391190.1 3396114 R 224308 CDS NP_391191.2 255767755 938471 complement(3396873..3397745) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15273097, 16816187; protein LiaG 3397745 liaG 938471 liaG Bacillus subtilis subsp. subtilis str. 168 protein LiaG NP_391191.2 3396873 R 224308 CDS NP_391192.1 16080365 938585 complement(3397846..3398523) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 16816187; Product type f: factor; lia operon expression modulator LiaH 3398523 liaH 938585 liaH Bacillus subtilis subsp. subtilis str. 168 lia operon expression modulator LiaH NP_391192.1 3397846 R 224308 CDS NP_391193.1 16080366 935958 complement(3398550..3398930) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15273097, 15849754, 16816187, 16850406; Product type t: transporter; protein LiaI 3398930 liaI 935958 liaI Bacillus subtilis subsp. subtilis str. 168 protein LiaI NP_391193.1 3398550 R 224308 CDS NP_391194.1 16080367 935970 complement(3399092..3400360) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3400360 yvqJ 935970 yvqJ Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391194.1 3399092 R 224308 CDS NP_391195.2 255767756 935972 complement(3400537..3401118) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 14704351, 17588214; Product type e : enzyme; Cob(i)yrinic acid a,c-diamide adenosyltransferase 3401118 yvqK 935972 yvqK Bacillus subtilis subsp. subtilis str. 168 Cob(i)yrinic acid a,c-diamide adenosyltransferase NP_391195.2 3400537 R 224308 CDS NP_391196.1 16080369 935968 complement(3401141..3402469) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type pt : transporter; ABC transporter ATP-binding protein 3402469 yvrA 935968 yvrA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391196.1 3401141 R 224308 CDS NP_391197.1 16080370 938583 complement(3402469..3403530) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351, 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3403530 yvrB 938583 yvrB Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391197.1 3402469 R 224308 CDS NP_391198.1 16080371 935980 complement(3403493..3404437) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14704351; Product type t : transporter; ABC transporter substrate-binding protein 3404437 yvrC 935980 yvrC Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein NP_391198.1 3403493 R 224308 CDS NP_391199.1 16080372 938584 3404835..3405626 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9922248; Product type pe : enzyme; oxidoreductase 3405626 yvrD 938584 yvrD Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391199.1 3404835 D 224308 CDS NP_391200.1 16080373 935979 complement(3405664..3406542) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; sugar lactone lactonase YvrE 3406542 yvrE 935979 yvrE Bacillus subtilis subsp. subtilis str. 168 sugar lactone lactonase YvrE NP_391200.1 3405664 R 224308 CDS NP_391201.2 255767757 935985 complement(3406614..3408356) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11717295, 16306698; Product type rc : receptor; sensor histidine kinase 3408356 yvrG 935985 yvrG Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391201.2 3406614 R 224308 CDS NP_391202.2 255767758 935974 complement(3408353..3409066) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 16306698; Product type r: regulator; transcriptional regulator 3409066 yvrH 935974 yvrH Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391202.2 3408353 R 224308 CDS YP_003097787.1 255767759 8302938 complement(3409219..3409458) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18573182, 19047353; Product type r: regulator; sigma-O factor regulatory protein RsoA 3409458 rsoA 8302938 rsoA Bacillus subtilis subsp. subtilis str. 168 sigma-O factor regulatory protein RsoA YP_003097787.1 3409219 R 224308 CDS NP_391203.2 255767760 935983 complement(3409462..3409992) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 18573182, 19047353; Product type r: regulator; RNA polymerase sigma factor SigO 3409992 sigO 935983 sigO Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigO NP_391203.2 3409462 R 224308 CDS YP_003097788.1 255767761 8303113 3410007..3410345 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 18573182, 19047353; hypothetical protein 3410345 yvrJ 8303113 yvrJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097788.1 3410007 D 224308 CDS NP_391204.1 16080377 938620 3410466..3411623 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10960116, 14697267, 14871895, 17459326, 18573182, 19047353; Product type e : enzyme; oxalate decarboxylase OxdC 3411623 oxdC 938620 oxdC Bacillus subtilis subsp. subtilis str. 168 oxalate decarboxylase OxdC NP_391204.1 3410466 D 224308 CDS NP_391205.1 16080378 935982 3411684..3412094 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane-bound negative regulator YvrL 3412094 yvrL 935982 yvrL Bacillus subtilis subsp. subtilis str. 168 membrane-bound negative regulator YvrL NP_391205.1 3411684 D 224308 CDS NP_391207.3 255767762 937213 complement(3412128..3413357) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter permease 3413357 yvrN 937213 yvrN Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391207.3 3412128 R 224308 CDS NP_391208.2 50812293 938472 complement(3413350..3414039) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11544226; Product type pt : transporter; ABC transporter ATP-binding protein 3414039 yvrO 938472 yvrO Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391208.2 3413350 R 224308 CDS NP_391209.1 16080382 938618 complement(3414023..3415216) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; efflux system protein YvrP 3415216 yvrP 938618 yvrP Bacillus subtilis subsp. subtilis str. 168 efflux system protein YvrP NP_391209.1 3414023 R 224308 CDS NP_391210.1 16080383 935994 complement(3415387..3416196) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 8388528, 8596459; Product type t : transporter; iron(3+)-hydroxamate import ATP-binding protein FhuC 3416196 fhuC 935994 fhuC Bacillus subtilis subsp. subtilis str. 168 iron(3+)-hydroxamate import ATP-binding protein FhuC NP_391210.1 3415387 R 224308 CDS NP_391211.1 16080384 938619 complement(3416212..3417222) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15802251, 15849754, 16850406, 8388528, 8596459; Product type t: transporter; iron(3+)-hydroxamate import system permease protein FhuG 3417222 fhuG 938619 fhuG Bacillus subtilis subsp. subtilis str. 168 iron(3+)-hydroxamate import system permease protein FhuG NP_391211.1 3416212 R 224308 CDS NP_391212.1 16080385 937085 complement(3417222..3418376) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16850406, 8388528; Product type t: transporter; iron(3+)-hydroxamate import system permease protein FhuB 3418376 fhuB 937085 fhuB Bacillus subtilis subsp. subtilis str. 168 iron(3+)-hydroxamate import system permease protein FhuB NP_391212.1 3417222 R 224308 CDS NP_391213.1 16080386 935996 3418474..3419421 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 8388528; Product type t: transporter; iron(3+)-hydroxamate-binding protein FhuD 3419421 fhuD 935996 fhuD Bacillus subtilis subsp. subtilis str. 168 iron(3+)-hydroxamate-binding protein FhuD NP_391213.1 3418474 D 224308 CDS NP_391214.1 16080387 936000 complement(3419656..3421065) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 14627808, 15849754, 16850406; Product type t: transporter; arginine/ornithine antiporter 3421065 lysP 936000 lysP Bacillus subtilis subsp. subtilis str. 168 arginine/ornithine antiporter NP_391214.1 3419656 R 224308 CDS YP_054593.1 50812294 2914269 complement(3421465..3421605) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9852018; Product type cp: cell process; small acid-soluble spore protein J 3421605 sspJ 2914269 sspJ Bacillus subtilis subsp. subtilis str. 168 small acid-soluble spore protein J YP_054593.1 3421465 R 224308 CDS NP_391215.1 16080388 935995 3421772..3422254 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; hypothetical protein 3422254 yvsG 935995 yvsG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391215.1 3421772 D 224308 CDS NP_391216.1 16080389 936006 3422354..3424207 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; lipoteichoic acid synthase 3424207 yvgJ 936006 yvgJ Bacillus subtilis subsp. subtilis str. 168 lipoteichoic acid synthase NP_391216.1 3422354 D 224308 CDS NP_391217.1 16080390 936008 complement(3424235..3425161) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; hypothetical protein 3425161 yvgK 936008 yvgK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391217.1 3424235 R 224308 CDS NP_391218.1 16080391 936003 3425272..3426054 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; ABC transporter substrate-binding protein 3426054 yvgL 936003 yvgL Bacillus subtilis subsp. subtilis str. 168 ABC transporter substrate-binding protein NP_391218.1 3425272 D 224308 CDS NP_391219.2 255767763 936009 3426035..3426718 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; molybdenum transport system permease protein YvgM 3426718 yvgM 936009 yvgM Bacillus subtilis subsp. subtilis str. 168 molybdenum transport system permease protein YvgM NP_391219.2 3426035 D 224308 CDS NP_391220.1 16080393 936001 complement(3426749..3427579) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16232966; Product type e: enzyme; glyoxal reductase 3427579 yvgN 936001 yvgN Bacillus subtilis subsp. subtilis str. 168 glyoxal reductase NP_391220.1 3426749 R 224308 CDS NP_391221.1 16080394 936024 3427802..3428287 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11988534; stress response protein YvgO 3428287 yvgO 936024 yvgO Bacillus subtilis subsp. subtilis str. 168 stress response protein YvgO NP_391221.1 3427802 D 224308 CDS NP_391222.1 16080395 936025 complement(3428331..3430343) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16021482, 16850406; Product type t: transporter; sodium, potassium, lithium and rubidium/H(+) antiporter 3430343 nhaK 936025 nhaK Bacillus subtilis subsp. subtilis str. 168 sodium, potassium, lithium and rubidium/H(+) antiporter NP_391222.1 3428331 R 224308 CDS NP_391223.1 16080396 938605 complement(3430598..3432313) 1 NC_000964.3 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide; sulfite reductase [NADPH] hemoprotein beta-component 3432313 yvgQ 938605 yvgQ Bacillus subtilis subsp. subtilis str. 168 sulfite reductase [NADPH] hemoprotein beta-component NP_391223.1 3430598 R 224308 CDS NP_391224.1 16080397 936022 complement(3432339..3434156) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11445163, 12169591; Product type e: enzyme; sulfite reductase [NADPH] flavoprotein alpha-component 3434156 cysJ 936022 cysJ Bacillus subtilis subsp. subtilis str. 168 sulfite reductase [NADPH] flavoprotein alpha-component NP_391224.1 3432339 R 224308 CDS NP_391225.1 16080398 936037 complement(3434327..3436651) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11544244; Product type e: enzyme; helicase IV 3436651 helD 936037 helD Bacillus subtilis subsp. subtilis str. 168 helicase IV NP_391225.1 3434327 R 224308 CDS NP_391226.1 16080399 936011 complement(3436849..3437457) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3437457 yvgT 936011 yvgT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391226.1 3436849 R 224308 CDS NP_391227.1 16080400 936042 complement(3437644..3438060) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10455116, 11872755, 15661011, 15849754, 16751195, 16850406, 17088376; Product type e: enzyme; disulfide bond formation protein C 3438060 bdbC 936042 bdbC Bacillus subtilis subsp. subtilis str. 168 disulfide bond formation protein C NP_391227.1 3437644 R 224308 CDS NP_391228.1 16080401 936031 complement(3438065..3438733) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11744713, 11872755, 12637552, 15661011, 17501922; Product type e: enzyme; disulfide bond formation protein D 3438733 bdbD 936031 bdbD Bacillus subtilis subsp. subtilis str. 168 disulfide bond formation protein D NP_391228.1 3438065 R 224308 CDS NP_391229.2 255767764 936034 complement(3438853..3440952) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 8037745, 7721839, 14663075, 12644235, 11934502, 11922674; Product type t: transporter; copper(I)-transporting ATPase 3440952 copB 936034 copB Bacillus subtilis subsp. subtilis str. 168 copper(I)-transporting ATPase NP_391229.2 3438853 R 224308 CDS NP_391230.2 255767765 937985 complement(3441121..3443529) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11922674, 11934502, 12644235, 14663075, 18215122; Product type t: transporter; copper-exporting P-type ATPase A 3443529 copA 937985 copA Bacillus subtilis subsp. subtilis str. 168 copper-exporting P-type ATPase A NP_391230.2 3441121 R 224308 CDS NP_391231.1 16080404 937974 complement(3443613..3443822) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934502, 12238948, 12590580, 14621987, 14663075, 15212800, 18419582; Product type f: factor; copper chaperone CopZ 3443822 copZ 937974 copZ Bacillus subtilis subsp. subtilis str. 168 copper chaperone CopZ NP_391231.1 3443613 R 224308 CDS NP_391232.1 16080405 936038 complement(3443896..3444201) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17143269, 18048925; Product type r: regulator; copper-sensing transcriptional repressor CsoR 3444201 csoR 936038 csoR Bacillus subtilis subsp. subtilis str. 168 copper-sensing transcriptional repressor CsoR NP_391232.1 3443896 R 224308 CDS NP_391233.1 16080406 936109 3444329..3445405 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937154; Product type pe : enzyme; oxidoreductase 3445405 yvaA 936109 yvaA Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391233.1 3444329 D 224308 CDS NP_391234.1 16080407 936142 complement(3445442..3446077) 1 NC_000964.3 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds; FMN-dependent NADH-azoreductase 2 3446077 yvaB 936142 yvaB Bacillus subtilis subsp. subtilis str. 168 FMN-dependent NADH-azoreductase 2 NP_391234.1 3445442 R 224308 CDS NP_391235.1 16080408 936143 complement(3446237..3448132) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3448132 yvaC 936143 yvaC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391235.1 3446237 R 224308 CDS NP_391236.1 16080409 936144 complement(3448295..3448696) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3448696 yvaD 936144 yvaD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391236.1 3448295 R 224308 CDS NP_391237.1 16080410 936156 complement(3448693..3449052) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11948170, 15849754, 16850406; Product type pt: transporter; membrane protein 3449052 yvaE 936156 yvaE Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391237.1 3448693 R 224308 CDS NP_391238.1 16080411 936128 complement(3449049..3449621) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaF 3449621 yvaF 936128 yvaF Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvaF NP_391238.1 3449049 R 224308 CDS NP_391239.1 16080412 936172 complement(3449732..3450526) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 3450526 yvaG 936172 yvaG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391239.1 3449732 R 224308 CDS NP_391240.1 16080413 936170 complement(3451248..3451718) 1 NC_000964.3 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 3451718 smpB 936170 smpB Bacillus subtilis subsp. subtilis str. 168 SsrA-binding protein NP_391240.1 3451248 R 224308 CDS NP_391241.1 16080414 938644 complement(3451863..3454202) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12399495, 15805522, 15983136; Product type e: enzyme; ribonuclease R 3454202 rnr 938644 rnr Bacillus subtilis subsp. subtilis str. 168 ribonuclease R NP_391241.1 3451863 R 224308 CDS NP_391242.1 16080415 938643 complement(3454221..3454967) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 1369099; Product type e: enzyme; carboxylesterase 3454967 yvaK 938643 yvaK Bacillus subtilis subsp. subtilis str. 168 carboxylesterase NP_391242.1 3454221 R 224308 CDS NP_391243.1 16080416 938477 complement(3455093..3455323) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074070, 10644701, 16243836; Product type f: factor; protein-export membrane protein SecG 3455323 secG 938477 secG Bacillus subtilis subsp. subtilis str. 168 protein-export membrane protein SecG NP_391243.1 3455093 R 224308 CDS NP_391244.1 16080417 938476 3455472..3456242 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; AB hydrolase superfamily protein YvaM 3456242 yvaM 938476 yvaM Bacillus subtilis subsp. subtilis str. 168 AB hydrolase superfamily protein YvaM NP_391244.1 3455472 D 224308 CDS NP_391245.1 16080418 936178 complement(3456282..3456515) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvzC 3456515 yvzC 936178 yvzC Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvzC NP_391245.1 3456282 R 224308 CDS NP_391246.1 16080419 936180 3456667..3457074 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553878, 17227471; Product type r: regulator; HTH-type transcriptional repressor RghR 3457074 rghRA 936180 rghRA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional repressor RghR NP_391246.1 3456667 D 224308 CDS NP_391247.1 16080420 938539 3457104..3457523 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator RghRB 3457523 rghRB 938539 rghRB Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator RghRB NP_391247.1 3457104 D 224308 CDS NP_391248.2 255767766 938478 3457615..3457941 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaP 3457941 yvaP 938478 yvaP Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvaP NP_391248.2 3457615 D 224308 CDS NP_391249.1 16080422 938479 3458066..3459766 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11872722, 8188684; Product type pr: regulator; sensory transducer protein YvaQ 3459766 yvaQ 938479 yvaQ Bacillus subtilis subsp. subtilis str. 168 sensory transducer protein YvaQ NP_391249.1 3458066 D 224308 CDS NP_391250.1 16080423 936226 complement(3459806..3460486) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; choline transport system permease protein OpuBD 3460486 opuBD 936226 opuBD Bacillus subtilis subsp. subtilis str. 168 choline transport system permease protein OpuBD NP_391250.1 3459806 R 224308 CDS NP_391251.1 16080424 938475 complement(3460503..3461423) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; choline-binding protein 3461423 opuBC 938475 opuBC Bacillus subtilis subsp. subtilis str. 168 choline-binding protein NP_391251.1 3460503 R 224308 CDS NP_391252.1 16080425 936225 complement(3461435..3462088) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; choline transport system permease protein OpuBB 3462088 opuBB 936225 opuBB Bacillus subtilis subsp. subtilis str. 168 choline transport system permease protein OpuBB NP_391252.1 3461435 R 224308 CDS NP_391253.1 16080426 936230 complement(3462105..3463250) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; choline transport ATP-binding protein OpuBA 3463250 opuBA 936230 opuBA Bacillus subtilis subsp. subtilis str. 168 choline transport ATP-binding protein OpuBA NP_391253.1 3462105 R 224308 CDS NP_391254.2 255767767 936233 3463534..3464067 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvaV 3464067 yvaV 936233 yvaV Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvaV NP_391254.2 3463534 D 224308 CDS NP_391255.1 16080428 938629 3464289..3464765 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16469701, 17069462; Product type f: factor; sporulation-delaying protein SdpA 3464765 sdpA 938629 sdpA Bacillus subtilis subsp. subtilis str. 168 sporulation-delaying protein SdpA NP_391255.1 3464289 D 224308 CDS NP_391256.1 16080429 936240 3464762..3465733 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 15849754, 16469701, 16850406, 17069462; Product type t : transporter; sporulation-delaying protein SdpB 3465733 sdpB 936240 sdpB Bacillus subtilis subsp. subtilis str. 168 sporulation-delaying protein SdpB NP_391256.1 3464762 D 224308 CDS NP_391257.1 16080430 936227 3465776..3466387 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 16469701, 17069462; Product type f: factor; killing factor SdpC 3466387 spbC 936227 spbC Bacillus subtilis subsp. subtilis str. 168 killing factor SdpC NP_391257.1 3465776 D 224308 CDS NP_391258.1 16080431 936238 complement(3466434..3467057) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 15849754, 16850406; Product type r: regulator; immunity protein SdpI 3467057 sdpI 936238 sdpI Bacillus subtilis subsp. subtilis str. 168 immunity protein SdpI NP_391258.1 3466434 R 224308 CDS NP_391259.1 16080432 936249 complement(3467054..3467326) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12817086, 17069462; Product type r: regulator; transcriptional repressor SdpR 3467326 sdpR 936249 sdpR Bacillus subtilis subsp. subtilis str. 168 transcriptional repressor SdpR NP_391259.1 3467054 R 224308 CDS NP_391260.1 16080433 937199 complement(3467546..3468235) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport system permease protein OpuCD 3468235 opuCD 937199 opuCD Bacillus subtilis subsp. subtilis str. 168 glycine betaine/carnitine/choline transport system permease protein OpuCD NP_391260.1 3467546 R 224308 CDS NP_391261.1 16080434 936248 complement(3468253..3469164) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; glycine betaine/carnitine/choline-binding protein OpuCC 3469164 opuCC 936248 opuCC Bacillus subtilis subsp. subtilis str. 168 glycine betaine/carnitine/choline-binding protein OpuCC NP_391261.1 3468253 R 224308 CDS NP_391262.1 16080435 937105 complement(3469184..3469837) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 15849754, 16850406, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport system permease protein OpuCB 3469837 opuCB 937105 opuCB Bacillus subtilis subsp. subtilis str. 168 glycine betaine/carnitine/choline transport system permease protein OpuCB NP_391262.1 3469184 R 224308 CDS NP_391263.1 16080436 937136 complement(3469860..3471002) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10216873, 9925583; Product type t: transporter; glycine betaine/carnitine/choline transport ATP-binding protein OpuCA 3471002 opuCA 937136 opuCA Bacillus subtilis subsp. subtilis str. 168 glycine betaine/carnitine/choline transport ATP-binding protein OpuCA NP_391263.1 3469860 R 224308 CDS NP_391264.1 16080437 936258 3471266..3471823 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvbF 3471823 yvbF 936258 yvbF Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvbF NP_391264.1 3471266 D 224308 CDS NP_391265.1 16080438 938636 complement(3471841..3472476) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3472476 yvbG 938636 yvbG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391265.1 3471841 R 224308 CDS NP_391266.1 16080439 938639 3472626..3473240 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3473240 yvbH 938639 yvbH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391266.1 3472626 D 224308 CDS NP_391267.1 16080440 938638 3473372..3474070 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; hypothetical protein 3474070 yvbI 938638 yvbI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391267.1 3473372 D 224308 CDS NP_391268.1 16080441 938637 complement(3474106..3475923) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15155184; membrane protein 3475923 yvbJ 938637 yvbJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391268.1 3474106 R 224308 CDS NP_391269.1 16080442 938642 3476043..3476510 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; N-acetyltransferase YvbK 3476510 yvbK 938642 yvbK Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YvbK NP_391269.1 3476043 D 224308 CDS NP_391270.1 16080443 938641 complement(3476555..3477847) 1 NC_000964.3 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; enolase 3477847 eno 938641 eno Bacillus subtilis subsp. subtilis str. 168 enolase NP_391270.1 3476555 R 224308 CDS NP_391271.1 16080444 938574 complement(3477877..3479412) 1 NC_000964.3 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 3479412 pgm 938574 pgm Bacillus subtilis subsp. subtilis str. 168 2,3-bisphosphoglycerate-independent phosphoglycerate mutase NP_391271.1 3477877 R 224308 CDS NP_391272.1 16080445 938626 complement(3479405..3480166) 1 NC_000964.3 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 3480166 tpiA 938626 tpiA Bacillus subtilis subsp. subtilis str. 168 triosephosphate isomerase NP_391272.1 3479405 R 224308 CDS NP_391273.1 16080446 938572 complement(3480197..3481381) 1 NC_000964.3 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 3481381 pgk 938572 pgk Bacillus subtilis subsp. subtilis str. 168 phosphoglycerate kinase NP_391273.1 3480197 R 224308 CDS NP_391274.1 16080447 938627 complement(3481698..3482705) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10799476, 12123463, 12634343, 17142398, 9588797; Product type e: enzyme; glyceraldehyde-3-phosphate dehydrogenase 1 3482705 gapA 938627 gapA Bacillus subtilis subsp. subtilis str. 168 glyceraldehyde-3-phosphate dehydrogenase 1 NP_391274.1 3481698 R 224308 CDS NP_391275.1 16080448 938570 complement(3482752..3483774) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11489127, 12622823, 17142398, 17293407, 18052209; Product type r: regulator; central glycolytic genes regulator 3483774 cggR 938570 cggR Bacillus subtilis subsp. subtilis str. 168 central glycolytic genes regulator NP_391275.1 3482752 R 224308 CDS NP_391276.1 16080449 938567 complement(3484072..3485466) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 9620981; Product type t: transporter; arabinose-proton symporter 3485466 araE 938567 araE Bacillus subtilis subsp. subtilis str. 168 arabinose-proton symporter NP_391276.1 3484072 R 224308 CDS NP_391277.1 16080450 938635 3485604..3486758 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10417639, 11418559, 12949161, 14973026, 16585763; Product type r: regulator; transcriptional repressor 3486758 araR 938635 araR Bacillus subtilis subsp. subtilis str. 168 transcriptional repressor NP_391277.1 3485604 D 224308 CDS NP_391278.1 16080451 938634 complement(3486807..3487817) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9836433; Product type pe : enzyme; hypothetical protein 3487817 yvbT 938634 yvbT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391278.1 3486807 R 224308 CDS NP_391279.1 16080452 937711 complement(3487974..3488852) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvbU 3488852 yvbU 937711 yvbU Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvbU NP_391279.1 3487974 R 224308 CDS NP_391280.1 16080453 936287 3488952..3489869 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10844694, 15849754, 16850406; Product type t : transporter; transporter 3489869 cyeB 936287 cyeB Bacillus subtilis subsp. subtilis str. 168 transporter NP_391280.1 3488952 D 224308 CDS NP_391281.1 16080454 936289 complement(3489910..3491253) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; amino acid permease YvbW 3491253 yvbW 936289 yvbW Bacillus subtilis subsp. subtilis str. 168 amino acid permease YvbW NP_391281.1 3489910 R 224308 CDS NP_391282.1 16080455 937709 complement(3491655..3492689) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12177332; Product type pe : enzyme; glycosylase YvbX 3492689 yvbX 937709 yvbX Bacillus subtilis subsp. subtilis str. 168 glycosylase YvbX NP_391282.1 3491655 R 224308 CDS NP_391283.1 16080456 937742 complement(3492797..3493519) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lactate utilization protein C 3493519 yvbY 937742 yvbY Bacillus subtilis subsp. subtilis str. 168 lactate utilization protein C NP_391283.1 3492797 R 224308 CDS NP_391284.1 16080457 938159 complement(3493519..3494958) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; lactate utilization protein B 3494958 yvfW 938159 yvfW Bacillus subtilis subsp. subtilis str. 168 lactate utilization protein B NP_391284.1 3493519 R 224308 CDS NP_391285.1 16080458 936297 complement(3494985..3495701) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16513748; Product type pe : enzyme; lactate utilization protein A 3495701 yvfV 936297 yvfV Bacillus subtilis subsp. subtilis str. 168 lactate utilization protein A NP_391285.1 3494985 R 224308 CDS NP_391286.1 16080459 938523 complement(3495876..3496478) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 3496478 yvfU 938523 yvfU Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391286.1 3495876 R 224308 CDS NP_391287.1 16080460 937702 complement(3496495..3497481) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; two-component sensor histidine kinase YvfU 3497481 yvfT 937702 yvfT Bacillus subtilis subsp. subtilis str. 168 two-component sensor histidine kinase YvfU NP_391287.1 3496495 R 224308 CDS NP_391288.1 16080461 936302 complement(3497614..3498351) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transport permease YvfS 3498351 yvfS 936302 yvfS Bacillus subtilis subsp. subtilis str. 168 transport permease YvfS NP_391288.1 3497614 R 224308 CDS NP_391289.1 16080462 936748 complement(3498352..3499257) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; ABC transporter ATP-binding protein 3499257 yvfR 936748 yvfR Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391289.1 3498352 R 224308 CDS NP_391290.1 16080463 935930 3499541..3500350 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11591687, 12620626, 15632289; Product type r: regulator; sigma factor SigB regulation protein RsbQ 3500350 rsbQ 935930 rsbQ Bacillus subtilis subsp. subtilis str. 168 sigma factor SigB regulation protein RsbQ NP_391290.1 3499541 D 224308 CDS NP_391291.1 16080464 936673 3500386..3501597 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10632888, 11591687, 15342585, 15632289, 16267279; Product type e: enzyme; phosphoserine phosphatase RsbP 3501597 rsbP 936673 rsbP Bacillus subtilis subsp. subtilis str. 168 phosphoserine phosphatase RsbP NP_391291.1 3500386 D 224308 CDS NP_391292.2 50812295 937086 complement(3501651..3502940) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178, 17056685; Product type e: enzyme; arabinogalactan endo-1,4-beta-galactosidase 3502940 ganB 937086 ganB Bacillus subtilis subsp. subtilis str. 168 arabinogalactan endo-1,4-beta-galactosidase NP_391292.2 3501651 R 224308 CDS NP_391293.1 16080466 936313 complement(3503020..3505083) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17056685, 9287030; Product type e: enzyme; arabinogalactan type I oligomer exo-hydrolase 3505083 ganA 936313 ganA Bacillus subtilis subsp. subtilis str. 168 arabinogalactan type I oligomer exo-hydrolase NP_391293.1 3503020 R 224308 CDS NP_391294.1 16080467 937991 complement(3505102..3505953) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 17056685; Product type t: transporter; arabinogalactan oligomer transport system permease protein GanQ 3505953 ganQ 937991 ganQ Bacillus subtilis subsp. subtilis str. 168 arabinogalactan oligomer transport system permease protein GanQ NP_391294.1 3505102 R 224308 CDS NP_391295.1 16080468 936323 complement(3505957..3507213) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11160890, 15849754, 16850406, 17056685; Product type t: transporter; arabinogalactan oligomer transport system permease protein GanP 3507213 ganP 936323 ganP Bacillus subtilis subsp. subtilis str. 168 arabinogalactan oligomer transport system permease protein GanP NP_391295.1 3505957 R 224308 CDS NP_391296.1 16080469 936329 complement(3507253..3508518) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11682178; Product type t: transporter; cyclodextrin-binding protein 3508518 cycB 936329 cycB Bacillus subtilis subsp. subtilis str. 168 cyclodextrin-binding protein NP_391296.1 3507253 R 224308 CDS NP_391297.1 16080470 936331 complement(3508659..3509651) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10486575, 17056685, 2104611, 9287030; Product type r: regulator; HTH-type transcriptional regulator GanR 3509651 ganR 936331 ganR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator GanR NP_391297.1 3508659 R 224308 CDS NP_391298.2 255767768 936332 complement(3509831..3510490) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18604637; Product type pr : regulator; HTH-type transcriptional regulator LutR 3510490 yvfI 936332 yvfI Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator LutR NP_391298.2 3509831 R 224308 CDS NP_391299.1 16080472 936322 3510780..3512471 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; L-lactate permease 3512471 yvfH 936322 yvfH Bacillus subtilis subsp. subtilis str. 168 L-lactate permease NP_391299.1 3510780 D 224308 CDS NP_391300.1 16080473 936362 complement(3512498..3513808) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274109, 12533460, 12634342, 16166551, 16585774; Product type r: regulator; RNA polymerase sigma-54 factor 3513808 sigL 936362 sigL Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma-54 factor NP_391300.1 3512498 R 224308 CDS NP_391301.1 16080474 936336 3513887..3514105 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3514105 yvfG 936336 yvfG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391301.1 3513887 D 224308 CDS NP_391302.1 16080475 936339 complement(3514115..3515083) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; pyruvyl transferase EpsO 3515083 epsO 936339 epsO Bacillus subtilis subsp. subtilis str. 168 pyruvyl transferase EpsO NP_391302.1 3514115 R 224308 CDS NP_391303.2 50812296 936364 complement(3515062..3516228) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; pyridoxal phosphate-dependent aminotransferase EpsN 3516228 epsN 936364 epsN Bacillus subtilis subsp. subtilis str. 168 pyridoxal phosphate-dependent aminotransferase EpsN NP_391303.2 3515062 R 224308 CDS NP_391304.1 16080477 936372 complement(3516233..3516883) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; acetyltransferase EpsM 3516883 epsM 936372 epsM Bacillus subtilis subsp. subtilis str. 168 acetyltransferase EpsM NP_391304.1 3516233 R 224308 CDS NP_391305.1 16080478 936365 complement(3516880..3517488) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; sugar transferase EpsL 3517488 epsL 936365 epsL Bacillus subtilis subsp. subtilis str. 168 sugar transferase EpsL NP_391305.1 3516880 R 224308 CDS YP_003097789.1 255767769 8302980 complement(3517485..3519002) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pt: transporter; membrane protein EpsK 3519002 epsK 8302980 epsK Bacillus subtilis subsp. subtilis str. 168 membrane protein EpsK YP_003097789.1 3517485 R 224308 CDS NP_391308.1 16080481 937131 complement(3518999..3520033) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; glycosyltransferase EpsJ 3520033 epsJ 937131 epsJ Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase EpsJ NP_391308.1 3518999 R 224308 CDS NP_391309.1 16080482 937256 complement(3520030..3521106) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15173185, 15661000; Product type pe: enzyme; pyruvyl transferase EpsI 3521106 epsI 937256 epsI Bacillus subtilis subsp. subtilis str. 168 pyruvyl transferase EpsI NP_391309.1 3520030 R 224308 CDS NP_391310.1 16080483 938630 complement(3521111..3522145) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15083514, 15661000; Product type pe: enzyme; glycosyltransferase EpsH 3522145 epsH 938630 epsH Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase EpsH NP_391310.1 3521111 R 224308 CDS NP_391311.1 16080484 937071 complement(3522170..3523273) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15175311, 15661000, 15849754, 16850406; Product type pe: enzyme; transmembrane protein EpsG 3523273 epsG 937071 epsG Bacillus subtilis subsp. subtilis str. 168 transmembrane protein EpsG NP_391311.1 3522170 R 224308 CDS NP_391312.1 16080485 938631 complement(3523270..3524424) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsF 3524424 epsF 938631 epsF Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase EpsF NP_391312.1 3523270 R 224308 CDS NP_391313.2 255767770 938633 complement(3524417..3525253) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsE 3525253 epsE 938633 epsE Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase EpsE NP_391313.2 3524417 R 224308 CDS NP_391314.1 16080487 938611 complement(3525250..3526395) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15175311, 15661000; Product type pe: enzyme; glycosyltransferase EpsD 3526395 epsD 938611 epsD Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase EpsD NP_391314.1 3525250 R 224308 CDS NP_391315.1 16080488 938571 complement(3526407..3528203) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15661000; Product type pe : enzyme; polysaccharide biosynthesis protein EpsC 3528203 epsC 938571 epsC Bacillus subtilis subsp. subtilis str. 168 polysaccharide biosynthesis protein EpsC NP_391315.1 3526407 R 224308 CDS NP_391316.1 16080489 938640 complement(3528462..3529145) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15661000, 15741737; Product type e : enzyme; tyrosine-protein kinase YveL 3529145 epsB 938640 epsB Bacillus subtilis subsp. subtilis str. 168 tyrosine-protein kinase YveL NP_391316.1 3528462 R 224308 CDS NP_391317.1 16080490 938582 complement(3529151..3529855) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12970183, 15661000; Product type r : regulator; hypothetical protein 3529855 epsA 938582 epsA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391317.1 3529151 R 224308 CDS NP_391318.1 16080491 938581 3530101..3530559 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18430133, 18647168; Product type r: regulator; HTH-type transcriptional regulator SlrR 3530559 slrR 938581 slrR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator SlrR NP_391318.1 3530101 D 224308 CDS NP_391319.1 16080492 938580 3530635..3532104 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7828905; Product type e : enzyme; para-nitrobenzyl esterase 3532104 pnbA 938580 pnbA Bacillus subtilis subsp. subtilis str. 168 para-nitrobenzyl esterase NP_391319.1 3530635 D 224308 CDS NP_391320.1 16080493 938579 complement(3532325..3532810) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12903944, 17295427, 18326577; Product type e: enzyme; phenolic acid decarboxylase PadC 3532810 padC 938579 padC Bacillus subtilis subsp. subtilis str. 168 phenolic acid decarboxylase PadC NP_391320.1 3532325 R 224308 CDS NP_391321.1 16080494 938578 complement(3532833..3533120) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3533120 yveG 938578 yveG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391321.1 3532833 R 224308 CDS NP_391322.1 16080495 938614 complement(3533196..3533288) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3533288 yveF 938614 yveF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391322.1 3533196 R 224308 CDS NP_391323.1 16080496 938575 complement(3533419..3534102) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 2054383, 9987136; Product type e : enzyme; amino acid racemase 3534102 racX 938575 racX Bacillus subtilis subsp. subtilis str. 168 amino acid racemase NP_391323.1 3533419 R 224308 CDS NP_391324.1 16080497 938615 complement(3534118..3535473) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533473, 14679248, 19063962, 7592498, 9987136; Product type e: enzyme; penicillin-binding protein 4* 3535473 pbpE 938615 pbpE Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 4* NP_391324.1 3534118 R 224308 CDS NP_391325.1 16080498 936413 3536012..3537433 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11320136, 11739774, 1400159, 15528654; Product type e: enzyme; levansucrase 3537433 sacB 936413 sacB Bacillus subtilis subsp. subtilis str. 168 levansucrase NP_391325.1 3536012 D 224308 CDS NP_391326.1 16080499 938616 3537507..3539057 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11739774, 15528654; Product type e: enzyme; levanbiose-producing levanase 3539057 levB 938616 levB Bacillus subtilis subsp. subtilis str. 168 levanbiose-producing levanase NP_391326.1 3537507 D 224308 CDS NP_391327.1 16080500 938612 3539165..3540727 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12730183, 15528654, 15849754, 16850406; Product type t: transporter; aspartate-proton symporter 3540727 yveA 938612 yveA Bacillus subtilis subsp. subtilis str. 168 aspartate-proton symporter NP_391327.1 3539165 D 224308 CDS NP_391328.1 16080501 936423 3540822..3541406 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvdT 3541406 yvdT 936423 yvdT Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvdT NP_391328.1 3540822 D 224308 CDS NP_391329.1 16080502 936401 3541488..3541823 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; membrane protein 3541823 yvdS 936401 yvdS Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391329.1 3541488 D 224308 CDS NP_391330.1 16080503 938613 3541823..3542143 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pm : membrane component; membrane protein 3542143 yvdR 938613 yvdR Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391330.1 3541823 D 224308 CDS NP_391331.1 16080504 936432 complement(3542179..3542691) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3542691 yvdQ 936432 yvdQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391331.1 3542179 R 224308 CDS NP_391332.1 16080505 936442 complement(3542943..3544286) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12562816; Product type f: factor; FAD-linked oxidoreductase YvdP 3544286 yvdP 936442 yvdP Bacillus subtilis subsp. subtilis str. 168 FAD-linked oxidoreductase YvdP NP_391332.1 3542943 R 224308 CDS NP_391333.1 16080506 936427 3544642..3545604 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650; Product type f: factor; sporulation hydrolase CotR 3545604 cotR 936427 cotR Bacillus subtilis subsp. subtilis str. 168 sporulation hydrolase CotR NP_391333.1 3544642 D 224308 CDS NP_391334.1 16080507 938625 3546234..3546827 1 NC_000964.3 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 3546827 clpP 938625 clpP Bacillus subtilis subsp. subtilis str. 168 ATP-dependent Clp protease proteolytic subunit NP_391334.1 3546234 D 224308 CDS NP_391335.1 16080508 938624 complement(3546873..3547553) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11081794; Product type e: enzyme; beta-phosphoglucomutase 3547553 pgcM 938624 pgcM Bacillus subtilis subsp. subtilis str. 168 beta-phosphoglucomutase NP_391335.1 3546873 R 224308 CDS NP_391336.1 16080509 938623 complement(3547550..3549235) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10229946, 16707683, 9573215; Product type e: enzyme; oligo-1,6-glucosidase 1 3549235 malL 938623 malL Bacillus subtilis subsp. subtilis str. 168 oligo-1,6-glucosidase 1 NP_391336.1 3547550 R 224308 CDS NP_391337.1 16080510 938621 complement(3549228..3551501) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type e: enzyme; maltose phosphorylase 3551501 yvdK 938621 yvdK Bacillus subtilis subsp. subtilis str. 168 maltose phosphorylase NP_391337.1 3549228 R 224308 CDS NP_391338.1 16080511 936479 complement(3551479..3552363) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16707683, 16850406; Product type pt: transporter; maltodextrin utilization protein YvdJ 3552363 yvdJ 936479 yvdJ Bacillus subtilis subsp. subtilis str. 168 maltodextrin utilization protein YvdJ NP_391338.1 3551479 R 224308 CDS NP_391339.1 16080512 936499 complement(3552369..3553205) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; maltodextrin transport system permease protein MdxG 3553205 mdxG 936499 mdxG Bacillus subtilis subsp. subtilis str. 168 maltodextrin transport system permease protein MdxG NP_391339.1 3552369 R 224308 CDS NP_391340.1 16080513 937063 complement(3553206..3554513) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16707683, 16850406; Product type t: transporter; maltodextrin transport system permease protein MdxF 3554513 mdxF 937063 mdxF Bacillus subtilis subsp. subtilis str. 168 maltodextrin transport system permease protein MdxF NP_391340.1 3553206 R 224308 CDS NP_391341.1 16080514 936522 complement(3554553..3555806) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type lp: lipoprotein; maltodextrin-binding protein MdxE 3555806 mdxE 936522 mdxE Bacillus subtilis subsp. subtilis str. 168 maltodextrin-binding protein MdxE NP_391341.1 3554553 R 224308 CDS NP_391342.1 16080515 936514 complement(3555902..3557671) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10825545, 16707683; Product type e: enzyme; glucan 1,4-alpha-maltohexaosidase 3557671 mdxD 936514 mdxD Bacillus subtilis subsp. subtilis str. 168 glucan 1,4-alpha-maltohexaosidase NP_391342.1 3555902 R 224308 CDS NP_391343.1 16080516 936460 complement(3557784..3558734) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16707683; Product type pr : regulator; HTH-type transcriptional regulator YvdE 3558734 mdxR 936460 mdxR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvdE NP_391343.1 3557784 R 224308 CDS NP_391344.1 16080517 936504 complement(3558940..3559515) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; LOG family protein YvdD 3559515 yvdD 936504 yvdD Bacillus subtilis subsp. subtilis str. 168 LOG family protein YvdD NP_391344.1 3558940 R 224308 CDS NP_391345.1 16080518 936515 3559632..3559952 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3559952 yvdC 936515 yvdC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391345.1 3559632 D 224308 CDS NP_391346.1 16080519 937217 complement(3559979..3561571) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; sulfate transporter YvdB 3561571 yvdB 937217 yvdB Bacillus subtilis subsp. subtilis str. 168 sulfate transporter YvdB NP_391346.1 3559979 R 224308 CDS NP_391347.1 16080520 937999 complement(3561590..3562183) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10611359; Product type pe : enzyme; carbonic anhydrase YvdA 3562183 yvdA 937999 yvdA Bacillus subtilis subsp. subtilis str. 168 carbonic anhydrase YvdA NP_391347.1 3561590 R 224308 CDS NP_391348.1 16080521 936519 3562566..3563543 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 2-ketogluconate reductase 3563543 yvcT 936519 yvcT Bacillus subtilis subsp. subtilis str. 168 2-ketogluconate reductase NP_391348.1 3562566 D 224308 CDS NP_391349.1 16080522 938473 complement(3563581..3565521) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; ABC transporter permease 3565521 yvcS 938473 yvcS Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391349.1 3563581 R 224308 CDS NP_391350.1 16080523 936524 complement(3565496..3566275) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12432961; Product type pt : transporter; ABC transporter ATP-binding protein 3566275 yvcR 936524 yvcR Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391350.1 3565496 R 224308 CDS NP_391351.1 16080524 938024 complement(3566358..3567428) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type rc: receptor; sensor histidine kinase 3567428 yvcQ 938024 yvcQ Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391351.1 3566358 R 224308 CDS NP_391352.1 16080525 936531 complement(3567422..3568135) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12432961, 14651641; Product type r: regulator; transcriptional regulator 3568135 yvcP 936531 yvcP Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391352.1 3567422 R 224308 CDS YP_003097790.1 255767771 8303070 3568282..3568491 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; lipoprotein 3568491 yvzJ 8303070 yvzJ Bacillus subtilis subsp. subtilis str. 168 lipoprotein YP_003097790.1 3568282 D 224308 CDS NP_391353.1 16080526 936525 complement(3568527..3569291) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acetyltransferase YvcN 3569291 yvcN 936525 yvcN Bacillus subtilis subsp. subtilis str. 168 acetyltransferase YvcN NP_391353.1 3568527 R 224308 CDS NP_391354.1 16080527 938474 complement(3569292..3569549) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559153, 10589728, 1136107, 12972249, 15126459, 16411239, 17142398; Product type r: regulator; HPr-like protein Crh 3569549 crh 938474 crh Bacillus subtilis subsp. subtilis str. 168 HPr-like protein Crh NP_391354.1 3569292 R 224308 CDS NP_391355.1 16080528 936540 complement(3569573..3570523) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10986251, 17603302; Product type pr: regulator; sporulation transcription regulator WhiA 3570523 whiA 936540 whiA Bacillus subtilis subsp. subtilis str. 168 sporulation transcription regulator WhiA NP_391355.1 3569573 R 224308 CDS NP_391356.2 50812297 936527 complement(3570546..3571499) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11888293, 16272399; Product type f: factor; hypothetical protein 3571499 yvcK 936527 yvcK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391356.2 3570546 R 224308 CDS NP_391357.1 16080530 936532 complement(3571501..3572388) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; UPF0042 nucleotide-binding protein YvcJ 3572388 yvcJ 936532 yvcJ Bacillus subtilis subsp. subtilis str. 168 UPF0042 nucleotide-binding protein YvcJ NP_391357.1 3571501 R 224308 CDS NP_391358.1 16080531 936528 complement(3572413..3572889) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; Nudix hydrolase YvcI 3572889 yvcI 936528 yvcI Bacillus subtilis subsp. subtilis str. 168 Nudix hydrolase YvcI NP_391358.1 3572413 R 224308 CDS NP_391359.1 16080532 936549 complement(3573207..3574157) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 14597697, 15659166; Product type e: enzyme; thioredoxin 3574157 trxB 936549 trxB Bacillus subtilis subsp. subtilis str. 168 thioredoxin NP_391359.1 3573207 R 224308 CDS NP_391360.1 16080533 936533 complement(3574363..3575784) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182, 16233686; Product type e: enzyme; peptidoglycan DL-endopeptidase CwlO 3575784 cwlO 936533 cwlO Bacillus subtilis subsp. subtilis str. 168 peptidoglycan DL-endopeptidase CwlO NP_391360.1 3574363 R 224308 CDS NP_391361.1 16080534 936542 complement(3576165..3577619) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; TPR repeat-containing protein YvcD 3577619 yvcD 936542 yvcD Bacillus subtilis subsp. subtilis str. 168 TPR repeat-containing protein YvcD NP_391361.1 3576165 R 224308 CDS NP_391362.1 16080535 936559 complement(3577745..3579514) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16405427, 18215075; Product type t: transporter; multidrug resistance ABC transporter ATP-binding/permease protein BmrA 3579514 bmrA 936559 bmrA Bacillus subtilis subsp. subtilis str. 168 multidrug resistance ABC transporter ATP-binding/permease protein BmrA NP_391362.1 3577745 R 224308 CDS NP_391363.1 16080536 936541 complement(3579679..3580038) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3580038 yvzA 936541 yvzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391363.1 3579679 R 224308 CDS NP_391364.1 16080537 936563 complement(3580053..3581963) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3581963 yvcB 936563 yvcB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391364.1 3580053 R 224308 CDS NP_391365.1 16080538 936576 complement(3581965..3582690) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17590234; Product type lp : lipoprotein; lipoprotein 3582690 yvcA 936576 yvcA Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_391365.1 3581965 R 224308 CDS NP_391366.1 16080539 936552 complement(3582936..3583565) 1 NC_000964.3 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis; histidine biosynthesis bifunctional protein HisIE 3583565 hisI 936552 hisI Bacillus subtilis subsp. subtilis str. 168 histidine biosynthesis bifunctional protein HisIE NP_391366.1 3582936 R 224308 CDS NP_391367.1 16080540 936554 complement(3583562..3584320) 1 NC_000964.3 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase; imidazole glycerol phosphate synthase subunit HisF 3584320 hisF 936554 hisF Bacillus subtilis subsp. subtilis str. 168 imidazole glycerol phosphate synthase subunit HisF NP_391367.1 3583562 R 224308 CDS NP_391368.1 16080541 936580 complement(3584317..3585054) 1 NC_000964.3 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide; 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 3585054 hisA 936580 hisA Bacillus subtilis subsp. subtilis str. 168 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase NP_391368.1 3584317 R 224308 CDS NP_391369.1 16080542 936590 complement(3585051..3585689) 1 NC_000964.3 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide; imidazole glycerol phosphate synthase subunit HisH 3585689 hisH 936590 hisH Bacillus subtilis subsp. subtilis str. 168 imidazole glycerol phosphate synthase subunit HisH NP_391369.1 3585051 R 224308 CDS NP_391370.1 16080543 936560 complement(3585690..3586274) 1 NC_000964.3 catalyzes the dehydration of D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate to 3-(imidazol-4-yl)-2-oxopropyl phosphate in histidine biosynthesis; imidazoleglycerol-phosphate dehydratase 3586274 hisB 936560 hisB Bacillus subtilis subsp. subtilis str. 168 imidazoleglycerol-phosphate dehydratase NP_391370.1 3585690 R 224308 CDS NP_391371.1 16080544 936584 complement(3586271..3587554) 1 NC_000964.3 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer; histidinol dehydrogenase 3587554 hisD 936584 hisD Bacillus subtilis subsp. subtilis str. 168 histidinol dehydrogenase NP_391371.1 3586271 R 224308 CDS NP_391372.1 16080545 936568 complement(3587551..3588192) 1 NC_000964.3 short form of enzyme; requires HisZ for function; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms heteromultimer of HisG and HisZ; ATP phosphoribosyltransferase 3588192 hisG 936568 hisG Bacillus subtilis subsp. subtilis str. 168 ATP phosphoribosyltransferase NP_391372.1 3587551 R 224308 CDS NP_391373.1 16080546 936602 complement(3588185..3589360) 1 NC_000964.3 May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine; ATP phosphoribosyltransferase regulatory subunit 3589360 hisZ 936602 hisZ Bacillus subtilis subsp. subtilis str. 168 ATP phosphoribosyltransferase regulatory subunit NP_391373.1 3588185 R 224308 CDS NP_391374.1 16080547 936591 3589611..3590363 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3590363 yvpB 936591 yvpB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391374.1 3589611 D 224308 CDS NP_391375.1 16080548 936594 3590603..3591268 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658655, 16514142; Product type e: enzyme; pectate lyase C 3591268 pelC 936594 pelC Bacillus subtilis subsp. subtilis str. 168 pectate lyase C NP_391375.1 3590603 D 224308 CDS NP_391376.1 16080549 936620 complement(3591288..3591806) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; acetyltransferase YvoF 3591806 yvoF 936620 yvoF Bacillus subtilis subsp. subtilis str. 168 acetyltransferase YvoF NP_391376.1 3591288 R 224308 CDS NP_391377.1 16080550 936613 complement(3591810..3592460) 1 NC_000964.3 hydrolyzes pyrophosphate formed during serine-46-phosphorylated HPr dephosphorylation; pyrophosphatase PpaX 3592460 hprP 936613 hprP Bacillus subtilis subsp. subtilis str. 168 pyrophosphatase PpaX NP_391377.1 3591810 R 224308 CDS NP_391378.1 16080551 936603 complement(3592457..3593395) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3593395 yvoD 936603 yvoD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391378.1 3592457 R 224308 CDS NP_391379.1 16080552 936609 complement(3593419..3594228) 1 NC_000964.3 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 3594228 lgt 936609 lgt Bacillus subtilis subsp. subtilis str. 168 prolipoprotein diacylglyceryl transferase NP_391379.1 3593419 R 224308 CDS NP_391380.1 16080553 936615 complement(3594242..3595174) 1 NC_000964.3 catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase 3595174 hprK 936615 hprK Bacillus subtilis subsp. subtilis str. 168 HPr kinase/phosphorylase NP_391380.1 3594242 R 224308 CDS NP_391381.1 16080554 936621 3595356..3596546 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14557261; Product type e: enzyme; N-acetylglucosamine-6-phosphate deacetylase 3596546 nagA 936621 nagA Bacillus subtilis subsp. subtilis str. 168 N-acetylglucosamine-6-phosphate deacetylase NP_391381.1 3595356 D 224308 CDS NP_391382.1 16080555 936619 3596543..3597271 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15755726; Product type e: enzyme; glucosamine-6-phosphate deaminase 1 3597271 nagBA 936619 nagBA Bacillus subtilis subsp. subtilis str. 168 glucosamine-6-phosphate deaminase 1 NP_391382.1 3596543 D 224308 CDS NP_391383.1 16080556 936626 3597289..3598020 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16207374; Product type r: regulator; HTH-type transcriptional repressor YvoA 3598020 yvoA 936626 yvoA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional repressor YvoA NP_391383.1 3597289 D 224308 CDS NP_391384.1 16080557 936623 complement(3598040..3601909) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3601909 yvnB 936623 yvnB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391384.1 3598040 R 224308 CDS NP_391385.1 16080558 936639 3602074..3602547 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvnA 3602547 yvnA 936639 yvnA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvnA NP_391385.1 3602074 D 224308 CDS NP_391386.1 16080559 936624 complement(3602588..3603805) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; cytochrome P450 CypX 3603805 cypX 936624 cypX Bacillus subtilis subsp. subtilis str. 168 cytochrome P450 CypX NP_391386.1 3602588 R 224308 CDS NP_391387.1 16080560 936633 complement(3603821..3604567) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3604567 yvmC 936633 yvmC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391387.1 3603821 R 224308 CDS NP_391388.1 16080561 936625 3604993..3605502 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvmB 3605502 yvmB 936625 yvmB Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvmB NP_391388.1 3604993 D 224308 CDS NP_391389.1 16080562 936643 3605523..3606734 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3606734 yvmA 936643 yvmA Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391389.1 3605523 D 224308 CDS NP_391390.1 16080563 936638 complement(3606762..3607121) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3607121 yvlD 936638 yvlD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391390.1 3606762 R 224308 CDS NP_391391.1 16080564 936642 complement(3607123..3607320) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; membrane protein 3607320 yvlC 936642 yvlC Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391391.1 3607123 R 224308 CDS NP_391392.1 16080565 936656 complement(3607325..3608422) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3608422 yvlB 936656 yvlB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391392.1 3607325 R 224308 CDS NP_391393.1 16080566 936640 complement(3608447..3608773) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3608773 yvlA 936640 yvlA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391393.1 3608447 R 224308 CDS NP_391394.1 16080567 936649 3608991..3609221 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3609221 yvkN 936649 yvkN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391394.1 3608991 D 224308 CDS NP_391395.1 16080568 936664 complement(3609420..3609902) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16936039; Product type ps : structure; flagellin 3609902 yvzB 936664 yvzB Bacillus subtilis subsp. subtilis str. 168 flagellin NP_391395.1 3609420 R 224308 CDS NP_391396.1 16080569 936646 complement(3610064..3612937) 1 NC_000964.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; UvrABC system protein A 3612937 uvrA 936646 uvrA Bacillus subtilis subsp. subtilis str. 168 UvrABC system protein A NP_391396.1 3610064 R 224308 CDS NP_391397.1 16080570 936663 complement(3612945..3614930) 1 NC_000964.3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; UvrABC system protein B 3614930 uvrB 936663 uvrB Bacillus subtilis subsp. subtilis str. 168 UvrABC system protein B NP_391397.1 3612945 R 224308 CDS NP_391398.1 16080571 936675 complement(3615116..3615346) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1744042; Product type pm : membrane component; general stress protein CsbA 3615346 csbA 936675 csbA Bacillus subtilis subsp. subtilis str. 168 general stress protein CsbA NP_391398.1 3615116 R 224308 CDS NP_391399.1 16080572 936657 3615793..3618288 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphotransferase YvkC 3618288 yvkC 936657 yvkC Bacillus subtilis subsp. subtilis str. 168 phosphotransferase YvkC NP_391399.1 3615793 D 224308 CDS NP_391400.1 16080573 936683 3618364..3618933 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YvkB 3618933 yvkB 936683 yvkB Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YvkB NP_391400.1 3618364 D 224308 CDS NP_391401.1 16080574 938566 3618964..3620298 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3620298 yvkA 938566 yvkA Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391401.1 3618964 D 224308 CDS NP_391402.1 16080575 936668 complement(3620346..3621539) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16030230, 16850406, 18976281, 19019154; Product type cp: cell process; cell division topological determinant MinJ 3621539 minJ 936668 minJ Bacillus subtilis subsp. subtilis str. 168 cell division topological determinant MinJ NP_391402.1 3620346 R 224308 CDS NP_391404.1 16080577 936678 complement(3622356..3623798) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14526016, 17557826; Product type e: enzyme; carboxy-terminal processing protease CtpB 3623798 ctpB 936678 ctpB Bacillus subtilis subsp. subtilis str. 168 carboxy-terminal processing protease CtpB NP_391404.1 3622356 R 224308 CDS NP_391405.1 16080578 936708 complement(3623938..3624828) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process; cell division protein FtsX 3624828 ftsX 936708 ftsX Bacillus subtilis subsp. subtilis str. 168 cell division protein FtsX NP_391405.1 3623938 R 224308 CDS NP_391406.1 16080579 936681 complement(3624821..3625507) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16352817, 17071757, 17307852, 18573177; Product type cp: cell process; cell division ATP-binding protein FtsE 3625507 ftsE 936681 ftsE Bacillus subtilis subsp. subtilis str. 168 cell division ATP-binding protein FtsE NP_391406.1 3624821 R 224308 CDS NP_391407.1 16080580 936703 complement(3625741..3626079) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10473570; Product type f: factor; cytochrome c-551 3626079 cccB 936703 cccB Bacillus subtilis subsp. subtilis str. 168 cytochrome c-551 NP_391407.1 3625741 R 224308 CDS NP_391408.1 16080581 938534 complement(3626128..3626973) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10473570, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3626973 yvjA 938534 yvjA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391408.1 3626128 R 224308 CDS NP_391409.1 16080582 936692 complement(join(3627139..3628167,3628169..3628240)) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1408743, 9696765; Product type f: factor; peptide chain release factor 2 3628240 prfB 936692 prfB Bacillus subtilis subsp. subtilis str. 168 peptide chain release factor 2 NP_391409.1 3627139 R 224308 CDS NP_391410.1 16080583 936711 complement(3628310..3630835) 1 NC_000964.3 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; protein translocase subunit SecA 3630835 secA 936711 secA Bacillus subtilis subsp. subtilis str. 168 protein translocase subunit SecA NP_391410.1 3628310 R 224308 CDS NP_391411.1 16080584 936715 complement(3631003..3631572) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11948165, 16324148, 17274076, 17277072; Product type f: factor; sigma-54 modulation protein 3631572 yvyD 936715 yvyD Bacillus subtilis subsp. subtilis str. 168 sigma-54 modulation protein NP_391411.1 3631003 R 224308 CDS YP_003097791.1 255767772 8303029 complement(3631763..3632140) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3632140 yvzG 8303029 yvzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097791.1 3631763 R 224308 CDS NP_391412.1 16080585 936718 complement(3632150..3632491) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12354229, 16952964; Product type s : structure; flagellar protein FliT 3632491 fliT 936718 fliT Bacillus subtilis subsp. subtilis str. 168 flagellar protein FliT NP_391412.1 3632150 R 224308 CDS NP_391413.1 16080586 936720 complement(3632488..3632889) 1 NC_000964.3 flagellin specific chaperone; flagellar protein FliS 3632889 fliS 936720 fliS Bacillus subtilis subsp. subtilis str. 168 flagellar protein FliS NP_391413.1 3632488 R 224308 CDS NP_391414.1 16080587 936728 complement(3632911..3634407) 1 NC_000964.3 involved in flagellin assembly; flagellar hook-associated protein 2 3634407 fliD 936728 fliD Bacillus subtilis subsp. subtilis str. 168 flagellar hook-associated protein 2 NP_391414.1 3632911 R 224308 CDS NP_391415.1 16080588 936737 complement(3634425..3634754) 1 NC_000964.3 possibly involved in flagella export; hypothetical protein 3634754 yvyC 936737 yvyC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391415.1 3634425 R 224308 CDS NP_391416.1 16080589 936742 complement(3634987..3635901) 1 NC_000964.3 structural flagella protein; flagellin 3635901 hag 936742 hag Bacillus subtilis subsp. subtilis str. 168 flagellin NP_391416.1 3634987 R 224308 CDS NP_391417.1 16080590 936731 complement(3636046..3636270) 1 NC_000964.3 affects carbohydrate metabolism; has regulatory role in many processes; carbon storage regulator homolog 3636270 csrA 936731 csrA Bacillus subtilis subsp. subtilis str. 168 carbon storage regulator homolog NP_391417.1 3636046 R 224308 CDS NP_391418.1 16080591 936732 complement(3636264..3636695) 1 NC_000964.3 binds to flagellin and appears to stabilize flagellin during flagella assembly; flagellar assembly factor FliW 3636695 yviF 936732 yviF Bacillus subtilis subsp. subtilis str. 168 flagellar assembly factor FliW NP_391418.1 3636264 R 224308 CDS NP_391419.1 16080592 936735 complement(3636716..3637291) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15033535; hypothetical protein 3637291 yviE 936735 yviE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391419.1 3636716 R 224308 CDS NP_391420.1 16080593 936738 complement(3637338..3638234) 1 NC_000964.3 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein 3 3638234 flgL 936738 flgL Bacillus subtilis subsp. subtilis str. 168 flagellar hook-associated protein 3 NP_391420.1 3637338 R 224308 CDS NP_391421.1 16080594 936736 complement(3638245..3639768) 1 NC_000964.3 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; flagellar hook-associated protein 1 3639768 flgK 936736 flgK Bacillus subtilis subsp. subtilis str. 168 flagellar hook-associated protein 1 NP_391421.1 3638245 R 224308 CDS NP_391422.1 16080595 936745 complement(3639787..3640269) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; hypothetical protein 3640269 yvyG 936745 yvyG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391422.1 3639787 R 224308 CDS NP_391423.1 16080596 936739 complement(3640285..3640551) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10207036, 10322161, 14762011, 16673084; Product type r: regulator; negative regulator of flagellin synthesis 3640551 flgM 936739 flgM Bacillus subtilis subsp. subtilis str. 168 negative regulator of flagellin synthesis NP_391423.1 3640285 R 224308 CDS NP_391424.1 16080597 936743 complement(3640632..3641051) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9696775; Product type pr : regulator; hypothetical protein 3641051 yvyF 936743 yvyF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391424.1 3640632 R 224308 CDS NP_391425.1 16080598 936747 complement(3641125..3641814) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16009133, 8045879, 8412657; Product type pt: transporter; ComF operon protein 3 3641814 comFC 936747 comFC Bacillus subtilis subsp. subtilis str. 168 ComF operon protein 3 NP_391425.1 3641125 R 224308 CDS NP_391426.1 16080599 936749 complement(3641811..3642107) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16009133, 8045879, 8412657; ComF operon protein 2 3642107 comFB 936749 comFB Bacillus subtilis subsp. subtilis str. 168 ComF operon protein 2 NP_391426.1 3641811 R 224308 CDS NP_391427.1 16080600 938537 complement(3642167..3643558) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11359569, 12123453, 16009133, 8045895; Product type e: enzyme; ComF operon protein 1 3643558 comFA 938537 comFA Bacillus subtilis subsp. subtilis str. 168 ComF operon protein 1 NP_391427.1 3642167 R 224308 CDS NP_391428.1 16080601 936763 complement(3643664..3644509) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17114254, 3926750; protein DegV 3644509 yviA 936763 yviA Bacillus subtilis subsp. subtilis str. 168 protein DegV NP_391428.1 3643664 R 224308 CDS NP_391429.1 16080602 936751 complement(3644607..3645296) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10908654, 11557812, 12471443, 12950930, 14563871, 15342569, 15598897; Product type r: regulator; transcriptional regulatory protein DegU 3645296 degU 936751 degU Bacillus subtilis subsp. subtilis str. 168 transcriptional regulatory protein DegU NP_391429.1 3644607 R 224308 CDS NP_391430.1 16080603 936752 complement(3645379..3646536) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 12183369, 12471443, 12950930, 14563871; Product type rc: receptor; signal transduction histidine-protein kinase/phosphatase DegS 3646536 degS 936752 degS Bacillus subtilis subsp. subtilis str. 168 signal transduction histidine-protein kinase/phosphatase DegS NP_391430.1 3645379 R 224308 CDS NP_391431.1 16080604 936754 3646753..3647406 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11116084; IMPACT family member YvyE 3647406 yvyE 936754 yvyE Bacillus subtilis subsp. subtilis str. 168 IMPACT family member YvyE NP_391431.1 3646753 D 224308 CDS NP_391432.1 16080605 936761 3647406..3648581 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator YvhJ 3648581 yvhJ 936761 yvhJ Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator YvhJ NP_391432.1 3647406 D 224308 CDS NP_391433.1 16080606 936757 complement(3648654..3649730) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12101296, 12682299, 15849754, 16850406, 17012386, 18156271; Product type e: enzyme; undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase 3649730 tagO 936757 tagO Bacillus subtilis subsp. subtilis str. 168 undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase NP_391433.1 3648654 R 224308 CDS NP_391434.1 16080607 938535 complement(3649875..3651068) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaH 3651068 tuaH 938535 tuaH Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis glycosyltransferase TuaH NP_391434.1 3649875 R 224308 CDS NP_391435.1 16080608 937965 complement(3651097..3651855) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaG 3651855 tuaG 937965 tuaG Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis glycosyltransferase TuaG NP_391435.1 3651097 R 224308 CDS NP_391436.1 16080609 936768 complement(3651879..3652559) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis protein TuaF 3652559 tuaF 936768 tuaF Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis protein TuaF NP_391436.1 3651879 R 224308 CDS NP_391437.1 16080610 936765 complement(3652588..3654054) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis protein TuaE 3654054 tuaE 936765 tuaE Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis protein TuaE NP_391437.1 3652588 R 224308 CDS NP_391438.1 16080611 936766 complement(3654139..3655524) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376820, 10913081, 12970183, 16000785; Product type e: enzyme; UDP-glucose 6-dehydrogenase TuaD 3655524 tuaD 936766 tuaD Bacillus subtilis subsp. subtilis str. 168 UDP-glucose 6-dehydrogenase TuaD NP_391438.1 3654139 R 224308 CDS NP_391439.1 16080612 936771 complement(3655586..3656755) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 4975313; Product type pe: enzyme; teichuronic acid biosynthesis glycosyltransferase TuaC 3656755 tuaC 936771 tuaC Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis glycosyltransferase TuaC NP_391439.1 3655586 R 224308 CDS NP_391440.1 16080613 936770 complement(3656752..3658203) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10048024, 11994144, 15849754, 16850406; Product type pt: transporter; teichuronic acid biosynthesis protein TuaB 3658203 tuaB 936770 tuaB Bacillus subtilis subsp. subtilis str. 168 teichuronic acid biosynthesis protein TuaB NP_391440.1 3656752 R 224308 CDS NP_391442.1 16080615 936777 complement(3659119..3660609) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079, 14594841, 17298895, 9537764; Product type e: enzyme; N-acetylmuramoyl-L-alanine amidase LytC 3660609 lytC 936777 lytC Bacillus subtilis subsp. subtilis str. 168 N-acetylmuramoyl-L-alanine amidase LytC NP_391442.1 3659119 R 224308 CDS NP_391443.1 16080616 936795 complement(3660648..3662765) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1357079; Product type r : regulator; amidase enhancer 3662765 lytB 936795 lytB Bacillus subtilis subsp. subtilis str. 168 amidase enhancer NP_391443.1 3660648 R 224308 CDS NP_391444.1 16080617 936784 complement(3662789..3663097) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10974124, 1357079; Product type lp: lipoprotein; membrane-bound protein LytA 3663097 lytA 936784 lytA Bacillus subtilis subsp. subtilis str. 168 membrane-bound protein LytA NP_391444.1 3662789 R 224308 CDS NP_391445.1 16080618 936787 3663281..3664201 1 NC_000964.3 attenuator function for control of operon expression; transcriptional regulator LytR 3664201 lytR 936787 lytR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator LytR NP_391445.1 3663281 D 224308 CDS NP_391446.1 16080619 936209 complement(3664241..3665383) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12107153; Product type e: enzyme; UDP-N-acetylglucosamine 2-epimerase 3665383 mnaA 936209 mnaA Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylglucosamine 2-epimerase NP_391446.1 3664241 R 224308 CDS NP_391447.1 16080620 936797 3665629..3666507 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17662947, 2846750, 8126437, 8320212, 9658024; Product type e: enzyme; UTP--glucose-1-phosphate uridylyltransferase 3666507 gtaB 936797 gtaB Bacillus subtilis subsp. subtilis str. 168 UTP--glucose-1-phosphate uridylyltransferase NP_391447.1 3665629 D 224308 CDS NP_391448.1 16080621 936775 complement(3667209..3669911) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16735734; Product type e: enzyme; minor teichoic acid biosynthesis protein GgaB 3669911 ggaB 936775 ggaB Bacillus subtilis subsp. subtilis str. 168 minor teichoic acid biosynthesis protein GgaB NP_391448.1 3667209 R 224308 CDS NP_391449.1 16080622 936798 complement(3670035..3671375) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16735734, 7704262; Product type e: enzyme; minor teichoic acid biosynthesis protein GgaA 3671375 ggaA 936798 ggaA Bacillus subtilis subsp. subtilis str. 168 minor teichoic acid biosynthesis protein GgaA NP_391449.1 3670035 R 224308 CDS NP_391451.1 16080623 936513 complement(3673564..3675147) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 17012386, 18156271, 7565096; Product type t: transporter; teichoic acids export ATP-binding protein TagH 3675147 tagH 936513 tagH Bacillus subtilis subsp. subtilis str. 168 teichoic acids export ATP-binding protein TagH NP_391451.1 3673564 R 224308 CDS NP_391452.1 16080624 936794 complement(3675167..3675994) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 15849754, 16850406, 17012386, 18156271, 7565096; Product type t: transporter; teichoic acid translocation permease protein TagG 3675994 tagG 936794 tagG Bacillus subtilis subsp. subtilis str. 168 teichoic acid translocation permease protein TagG NP_391452.1 3675167 R 224308 CDS NP_391453.1 16080625 936803 complement(3676159..3678399) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386; Product type e: enzyme; CDP-glycerol:poly 3678399 tagF 936803 tagF Bacillus subtilis subsp. subtilis str. 168 CDP-glycerol:poly NP_391453.1 3676159 R 224308 CDS NP_391454.1 16080626 936804 complement(3678399..3680420) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 17012386, 2507871, 9457886; Product type e : enzyme; poly(glycerol-phosphate) alpha-glucosyltransferase 3680420 tagE 936804 tagE Bacillus subtilis subsp. subtilis str. 168 poly(glycerol-phosphate) alpha-glucosyltransferase NP_391454.1 3678399 R 224308 CDS NP_391455.1 16080627 936809 complement(3680581..3680970) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11673441, 12637027, 12637499, 12682299, 16141206, 16689786, 17012386; Product type e: enzyme; glycerol-3-phosphate cytidylyltransferase 3680970 tagD 936809 tagD Bacillus subtilis subsp. subtilis str. 168 glycerol-3-phosphate cytidylyltransferase NP_391455.1 3680581 R 224308 CDS NP_391456.1 16080628 936810 3681370..3682140 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12682299, 16141206, 16689786, 16953575, 17012386; Product type e: enzyme; N-acetylmannosaminyltransferase 3682140 tagA 936810 tagA Bacillus subtilis subsp. subtilis str. 168 N-acetylmannosaminyltransferase NP_391456.1 3681370 D 224308 CDS NP_391457.1 16080629 936813 3682173..3683318 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 16141206, 16150696, 16689786, 17012386, 18156271; Product type e: enzyme; CDP-glycerol:glycerophosphate glycerophosphotransferase 3683318 tagB 936813 tagB Bacillus subtilis subsp. subtilis str. 168 CDP-glycerol:glycerophosphate glycerophosphotransferase NP_391457.1 3682173 D 224308 CDS NP_391458.1 16080630 936812 3683438..3684766 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16269821, 7952180; Product type pe: enzyme; major teichoic acid biosynthesis protein C 3684766 tagC 936812 tagC Bacillus subtilis subsp. subtilis str. 168 major teichoic acid biosynthesis protein C NP_391458.1 3683438 D 224308 CDS NP_391459.1 16080631 936822 complement(3684826..3687468) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9537764, 10206711; Product type e: enzyme; beta-N-acetylglucosaminidase 3687468 lytD 936822 lytD Bacillus subtilis subsp. subtilis str. 168 beta-N-acetylglucosaminidase NP_391459.1 3684826 R 224308 CDS NP_391460.1 16080632 936815 complement(3687597..3688547) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10704478, 7581999; Product type e: enzyme; mannose-6-phosphate isomerase YvyI 3688547 yvyI 936815 yvyI Bacillus subtilis subsp. subtilis str. 168 mannose-6-phosphate isomerase YvyI NP_391460.1 3687597 R 224308 CDS NP_391461.2 255767773 936814 3688812..3690263 1 NC_000964.3 Evidence 1c: Function experimentally demonstrated in the studied genus; PubMedId: 10411756, 15774895, 3110007, 8012571; Product type rc: receptor; spore germination protein B1 3690263 gerBA 936814 gerBA Bacillus subtilis subsp. subtilis str. 168 spore germination protein B1 NP_391461.2 3688812 D 224308 CDS NP_391462.2 255767774 936827 3690269..3691375 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 15849754, 16352818, 16850406; Product type rc: receptor; spore germination protein B2 3691375 gerBB 936827 gerBB Bacillus subtilis subsp. subtilis str. 168 spore germination protein B2 NP_391462.2 3690269 D 224308 CDS NP_391463.1 16080635 936819 3691372..3692496 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15774895, 16352818; Product type lp: lipoprotein; spore germination protein B3 3692496 gerBC 936819 gerBC Bacillus subtilis subsp. subtilis str. 168 spore germination protein B3 NP_391463.1 3691372 D 224308 CDS NP_391464.2 255767775 936832 complement(3692533..3693906) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; metabolite transport protein YwtG 3693906 ywtG 936832 ywtG Bacillus subtilis subsp. subtilis str. 168 metabolite transport protein YwtG NP_391464.2 3692533 R 224308 CDS NP_391465.2 255767776 936823 3694239..3695207 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; transcriptional regulator YwtF 3695207 ywtF 936823 ywtF Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator YwtF NP_391465.2 3694239 D 224308 CDS NP_391466.1 16080638 936824 3695363..3696223 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3696223 ywtE 936824 ywtE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391466.1 3695363 D 224308 CDS NP_391467.1 16080639 936837 complement(3696257..3697498) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073126, 12644511; Product type e: enzyme; gamma-dl-glutamyl hydrolase 3697498 pgdS 936837 pgdS Bacillus subtilis subsp. subtilis str. 168 gamma-dl-glutamyl hydrolase NP_391467.1 3696257 R 224308 CDS NP_391468.1 16080640 936828 complement(3697639..3697806) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16267300; Product type f: factor; hypothetical protein 3697806 pgsE 936828 pgsE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391468.1 3697639 R 224308 CDS NP_391469.1 16080641 936830 complement(3697821..3698963) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 12644511; Product type e: enzyme; PGA biosynthesis protein CapA 3698963 pgsA 936830 pgsA Bacillus subtilis subsp. subtilis str. 168 PGA biosynthesis protein CapA NP_391469.1 3697821 R 224308 CDS NP_391470.1 16080642 936840 complement(3698982..3699431) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11606194, 11751809, 15849754, 16689787, 16850406; Product type e: enzyme; PGA biosynthesis protein CapC 3699431 pgsC 936840 pgsC Bacillus subtilis subsp. subtilis str. 168 PGA biosynthesis protein CapC NP_391470.1 3698982 R 224308 CDS NP_391471.2 255767777 936833 complement(3699446..3700627) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11606194, 11751809, 12644511; Product type e : enzyme; PGA synthase CapB 3700627 pgsB 936833 pgsB Bacillus subtilis subsp. subtilis str. 168 PGA synthase CapB NP_391471.2 3699446 R 224308 CDS NP_391472.1 16080644 936836 3701411..3702391 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16519689; Product type r: regulator; ribose operon repressor 3702391 rbsR 936836 rbsR Bacillus subtilis subsp. subtilis str. 168 ribose operon repressor NP_391472.1 3701411 D 224308 CDS NP_391473.1 16080645 936844 3702393..3703274 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16978644, 7921236; Product type e: enzyme; ribokinase 3703274 rbsK 936844 rbsK Bacillus subtilis subsp. subtilis str. 168 ribokinase NP_391473.1 3702393 D 224308 CDS NP_391474.1 16080646 936846 3703271..3703666 1 NC_000964.3 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source; D-ribose pyranase 3703666 rbsD 936846 rbsD Bacillus subtilis subsp. subtilis str. 168 D-ribose pyranase NP_391474.1 3703271 D 224308 CDS NP_391475.1 16080647 936839 3703682..3705163 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter; ribose import ATP-binding protein RbsA 3705163 rbsA 936839 rbsA Bacillus subtilis subsp. subtilis str. 168 ribose import ATP-binding protein RbsA NP_391475.1 3703682 D 224308 CDS NP_391476.1 16080648 936841 3705165..3706133 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7921236; Product type t: transporter; ribose transport system permease RbsC 3706133 rbsC 936841 rbsC Bacillus subtilis subsp. subtilis str. 168 ribose transport system permease RbsC NP_391476.1 3705165 D 224308 CDS NP_391477.1 16080649 936848 3706145..3707062 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7921236; Product type t : transporter; D-ribose-binding protein 3707062 rbsB 936848 rbsB Bacillus subtilis subsp. subtilis str. 168 D-ribose-binding protein NP_391477.1 3706145 D 224308 CDS NP_391478.1 16080650 936850 3707144..3707680 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15187182; cell wall-binding protein YwsB 3707680 ywsB 936850 ywsB Bacillus subtilis subsp. subtilis str. 168 cell wall-binding protein YwsB NP_391478.1 3707144 D 224308 CDS NP_391479.1 16080651 936847 3707836..3708132 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 11782522; hypothetical protein 3708132 ywsA 936847 ywsA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391479.1 3707836 D 224308 CDS NP_391480.1 16080652 936853 complement(3708172..3708699) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11782522; Product type e: enzyme; general stress protein 14 3708699 ywrO 936853 ywrO Bacillus subtilis subsp. subtilis str. 168 general stress protein 14 NP_391480.1 3708172 R 224308 CDS NP_391481.1 16080653 936857 complement(3708799..3709566) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10972805, 12363365, 17183216, 7685336; Product type e: enzyme; alpha-acetolactate decarboxylase 3709566 alsD 936857 alsD Bacillus subtilis subsp. subtilis str. 168 alpha-acetolactate decarboxylase NP_391481.1 3708799 R 224308 CDS NP_391482.2 255767778 936852 complement(3709628..3711340) 1 NC_000964.3 catalyzes the formation of 2-acetolactate from pyruvate in stationary phase; acetolactate synthase 3711340 alsS 936852 alsS Bacillus subtilis subsp. subtilis str. 168 acetolactate synthase NP_391482.2 3709628 R 224308 CDS NP_391483.1 16080655 936860 3711498..3712406 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 10972805, 12363365, 15978075, 17183216, 7685336; Product type r : regulator; HTH-type transcriptional regulator AlsR 3712406 alsR 936860 alsR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator AlsR NP_391483.1 3711498 D 224308 CDS NP_391484.1 16080656 936864 3712617..3713945 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; arsenical pump membrane protein 3713945 ywrK 936864 ywrK Bacillus subtilis subsp. subtilis str. 168 arsenical pump membrane protein NP_391484.1 3712617 D 224308 CDS NP_391485.1 16080657 936867 complement(3714002..3714679) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14762006; hypothetical protein 3714679 ywrJ 936867 ywrJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391485.1 3714002 R 224308 CDS NP_391486.1 16080658 936870 complement(3714739..3715881) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10559171, 11737650, 14762006, 8755863; Product type f: factor; spore coat protein B 3715881 cotB 936870 cotB Bacillus subtilis subsp. subtilis str. 168 spore coat protein B NP_391486.1 3714739 R 224308 CDS NP_391487.1 16080659 936858 complement(3716009..3717097) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14762006; Product type f: factor; inner spore coat protein H 3717097 cotH 936858 cotH Bacillus subtilis subsp. subtilis str. 168 inner spore coat protein H NP_391487.1 3716009 R 224308 CDS NP_391488.1 16080660 936865 3717238..3717825 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11737650, 14762006, 15621419; Product type cp: cell process; spore coat protein G 3717825 cotG 936865 cotG Bacillus subtilis subsp. subtilis str. 168 spore coat protein G NP_391488.1 3717238 D 224308 CDS NP_391489.1 16080661 936871 3717999..3718616 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3718616 ywrF 936871 ywrF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391489.1 3717999 D 224308 CDS NP_391490.1 16080662 936874 3718794..3719129 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3719129 ywrE 936874 ywrE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391490.1 3718794 D 224308 CDS NP_391491.1 16080663 936884 complement(3719134..3720711) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762019; Product type pe : enzyme; gamma-glutamyltransferase YwrD 3720711 ywrD 936884 ywrD Bacillus subtilis subsp. subtilis str. 168 gamma-glutamyltransferase YwrD NP_391491.1 3719134 R 224308 CDS NP_391492.1 16080664 936886 3720925..3721401 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwrC 3721401 ywrC 936886 ywrC Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwrC NP_391492.1 3720925 D 224308 CDS NP_391493.1 16080665 936876 3721415..3722008 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3722008 ywrB 936876 ywrB Bacillus subtilis subsp. subtilis str. 168 transporter NP_391493.1 3721415 D 224308 CDS NP_391494.1 16080666 936879 3722005..3722541 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3722541 ywrA 936879 ywrA Bacillus subtilis subsp. subtilis str. 168 transporter NP_391494.1 3722005 D 224308 CDS NP_391495.1 16080667 936881 complement(3722568..3722789) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3722789 ywqO 936881 ywqO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391495.1 3722568 R 224308 CDS NP_391496.1 16080668 936882 complement(3722786..3723331) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; NAD(P)H-dependent FMN-containing oxidoreductase YwqN 3723331 ywqN 936882 ywqN Bacillus subtilis subsp. subtilis str. 168 NAD(P)H-dependent FMN-containing oxidoreductase YwqN NP_391496.1 3722786 R 224308 CDS NP_391497.1 16080669 936887 3723454..3724335 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwqM 3724335 ywqM 936887 ywqM Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwqM NP_391497.1 3723454 D 224308 CDS NP_391498.2 255767779 936894 complement(3724420..3725136) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1692969; Product type pe : enzyme; endonuclease V 3725136 ywqL 936894 ywqL Bacillus subtilis subsp. subtilis str. 168 endonuclease V NP_391498.2 3724420 R 224308 CDS NP_391499.1 16080671 936888 complement(3725146..3725610) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3725610 ywqK 936888 ywqK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391499.1 3725146 R 224308 CDS NP_391500.1 16080672 936885 complement(3725600..3727408) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 3727408 ywqJ 936885 ywqJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391500.1 3725600 R 224308 CDS NP_391501.1 16080673 937912 complement(3727427..3727687) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3727687 ywqI 937912 ywqI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391501.1 3727427 R 224308 CDS NP_391502.1 16080674 937905 complement(3727697..3728119) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15101989; hypothetical protein 3728119 ywqH 937905 ywqH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391502.1 3727697 R 224308 CDS NP_391503.1 16080675 937891 complement(3728511..3729296) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3729296 ywqG 937891 ywqG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391503.1 3728511 R 224308 CDS NP_391504.1 16080676 936890 complement(3729488..3730810) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15741737, 15866923, 16415592; Product type e: enzyme; UDP-glucose 6-dehydrogenase YwqF 3730810 ywqF 936890 ywqF Bacillus subtilis subsp. subtilis str. 168 UDP-glucose 6-dehydrogenase YwqF NP_391504.1 3729488 R 224308 CDS NP_391505.1 16080677 936893 complement(3731005..3731769) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15866923, 16415592, 16549871; Product type e: enzyme; tyrosine-protein phosphatase YwqE 3731769 ywqE 936893 ywqE Bacillus subtilis subsp. subtilis str. 168 tyrosine-protein phosphatase YwqE NP_391505.1 3731005 R 224308 CDS NP_391506.1 16080678 936896 complement(3731822..3732535) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183, 15741737, 16415592, 16549871, 17367396; Product type e: enzyme; tyrosine-protein kinase YwqD 3732535 ptkA 936896 ptkA Bacillus subtilis subsp. subtilis str. 168 tyrosine-protein kinase YwqD NP_391506.1 3731822 R 224308 CDS NP_391507.1 16080679 936897 complement(3732525..3733271) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12970183; Product type f: factor; capsular polysaccharide biosynthesis protein YwqC 3733271 ywqC 936897 ywqC Bacillus subtilis subsp. subtilis str. 168 capsular polysaccharide biosynthesis protein YwqC NP_391507.1 3732525 R 224308 CDS YP_003097792.1 255767780 8303126 complement(3733505..3733648) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3733648 ywzD 8303126 ywzD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097792.1 3733505 R 224308 CDS NP_391508.2 255767781 936903 3733852..3735462 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3735462 ywqB 936903 ywqB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391508.2 3733852 D 224308 CDS NP_391509.1 16080681 936906 3735449..3738217 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; ATP-dependent helicase YwqA 3738217 ywqA 936906 ywqA Bacillus subtilis subsp. subtilis str. 168 ATP-dependent helicase YwqA NP_391509.1 3735449 D 224308 CDS NP_391510.1 16080682 936907 complement(3738343..3739200) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; phosphatase YwpJ 3739200 ywpJ 936907 ywpJ Bacillus subtilis subsp. subtilis str. 168 phosphatase YwpJ NP_391510.1 3738343 R 224308 CDS NP_391511.1 16080683 936908 complement(3739206..3739982) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11491085; Product type r: regulator; HTH-type transcriptional repressor GlcR 3739982 glcR 936908 glcR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional repressor GlcR NP_391511.1 3739206 R 224308 CDS NP_391512.2 255767782 936910 complement(3740206..3740547) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 14762004, 16009133, 16549871; Product type f : factor; single-stranded DNA-binding protein SsbB 3740547 ssbB 936910 ssbB Bacillus subtilis subsp. subtilis str. 168 single-stranded DNA-binding protein SsbB NP_391512.2 3740206 R 224308 CDS NP_391513.1 16080685 936912 complement(3740624..3741007) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3741007 ywpG 936912 ywpG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391513.1 3740624 R 224308 CDS NP_391514.1 16080686 936915 3741182..3741592 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3741592 ywpF 936915 ywpF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391514.1 3741182 D 224308 CDS NP_391515.1 16080687 936904 complement(3741732..3742040) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15187182; Product type pe : enzyme; sortase 3742040 ywpE 936904 ywpE Bacillus subtilis subsp. subtilis str. 168 sortase NP_391515.1 3741732 R 224308 CDS NP_391516.1 16080688 936914 3742384..3743220 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16740923; Product type prc : receptor; hypothetical protein 3743220 ywpD 936914 ywpD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391516.1 3742384 D 224308 CDS NP_391517.1 16080689 936909 complement(3743267..3743659) 1 NC_000964.3 homopentamer; channel that opens in response to pressure or hypoosmotic shock; large-conductance mechanosensitive channel 3743659 mscL 936909 mscL Bacillus subtilis subsp. subtilis str. 168 large-conductance mechanosensitive channel NP_391517.1 3743267 R 224308 CDS NP_391518.2 255767783 936918 complement(3743732..3744157) 1 NC_000964.3 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ 3744157 fabZ 936918 fabZ Bacillus subtilis subsp. subtilis str. 168 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ NP_391518.2 3743732 R 224308 CDS NP_391519.1 16080691 936919 3744349..3745413 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17227471; Product type r: regulator; response regulator aspartate phosphatase D 3745413 rapD 936919 rapD Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase D NP_391519.1 3744349 D 224308 CDS NP_391520.2 255767784 936913 complement(3745436..3746245) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: structure; flagellar hook-basal body complex protein FlhP 3746245 flhP 936913 flhP Bacillus subtilis subsp. subtilis str. 168 flagellar hook-basal body complex protein FlhP NP_391520.2 3745436 R 224308 CDS NP_391521.1 16080693 936927 complement(3746279..3747091) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16621824, 1905667; Product type ps: structure; flagellar hook-basal body complex protein FlhO 3747091 flhO 936927 flhO Bacillus subtilis subsp. subtilis str. 168 flagellar hook-basal body complex protein FlhO NP_391521.1 3746279 R 224308 CDS NP_391522.2 50812298 936916 complement(3747254..3748255) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11290328, 12530960, 14588250, 15745453, 17064365; Product type f: factor; MreB-like protein 3748255 mbl 936916 mbl Bacillus subtilis subsp. subtilis str. 168 MreB-like protein NP_391522.2 3747254 R 224308 CDS NP_391523.1 16080695 936917 complement(3748421..3748702) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15598884, 9023218, 9324264; Product type r: regulator; stage III sporulation protein D 3748702 spoIIID 936917 spoIIID Bacillus subtilis subsp. subtilis str. 168 stage III sporulation protein D NP_391523.1 3748421 R 224308 CDS NP_391524.1 16080696 938188 complement(3748717..3748827) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 9023218; Product type ph : phenotype; protein usd 3748827 usd 938188 usd Bacillus subtilis subsp. subtilis str. 168 protein usd NP_391524.1 3748717 R 224308 CDS NP_391525.1 16080697 936923 3749052..3749465 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwoH 3749465 ywoH 936923 ywoH Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwoH NP_391525.1 3749052 D 224308 CDS NP_391526.1 16080698 936928 3749487..3750677 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3750677 ywoG 936928 ywoG Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391526.1 3749487 D 224308 CDS NP_391527.1 16080699 936925 complement(3750768..3752174) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15266115; Product type pe : enzyme; hypothetical protein 3752174 ywoF 936925 ywoF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391527.1 3750768 R 224308 CDS NP_391528.1 16080700 936935 complement(3752280..3753752) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11344136, 12029039, 15849754, 16850406; Product type t: transporter; allantoin permease 3753752 pucI 936935 pucI Bacillus subtilis subsp. subtilis str. 168 allantoin permease NP_391528.1 3752280 R 224308 CDS NP_391529.1 16080701 938533 complement(3753933..3755291) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3755291 ywoD 938533 ywoD Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391529.1 3753933 R 224308 CDS NP_391530.2 255767785 936934 complement(3755291..3755860) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; isochorismatase 3755860 ywoC 936934 ywoC Bacillus subtilis subsp. subtilis str. 168 isochorismatase NP_391530.2 3755291 R 224308 CDS NP_391531.1 16080703 936938 complement(3756044..3756508) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3756508 ywoB 936938 ywoB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391531.1 3756044 R 224308 CDS NP_391532.1 16080704 936933 3756790..3758004 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 15849754, 16850406, 17001076; Product type t: transporter; ammonium transporter NrgA 3758004 amtB 936933 amtB Bacillus subtilis subsp. subtilis str. 168 ammonium transporter NrgA NP_391532.1 3756790 D 224308 CDS NP_391533.1 16080705 936937 3758016..3758366 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14600241, 17001076; Product type r: regulator; nitrogen regulatory PII-like protein 3758366 glnK 936937 glnK Bacillus subtilis subsp. subtilis str. 168 nitrogen regulatory PII-like protein NP_391533.1 3758016 D 224308 CDS NP_391534.1 16080706 936946 3758547..3759128 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12486040, 14612242, 15838020, 15849754, 15946938, 16850406; Product type e : enzyme; undecaprenyl-diphosphatase BcrC 3759128 bcrC 936946 bcrC Bacillus subtilis subsp. subtilis str. 168 undecaprenyl-diphosphatase BcrC NP_391534.1 3758547 D 224308 CDS NP_391535.1 16080707 936936 complement(3759169..3759591) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14762009, 15849754, 16850406; Product type pm: membrane component; membrane protein 3759591 ywnJ 936936 ywnJ Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391535.1 3759169 R 224308 CDS NP_391536.1 16080708 936951 complement(3759702..3760553) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16164552, 16959571, 17121846, 18077456; Product type f: factor; stage II sporulation protein Q 3760553 spoIIQ 936951 spoIIQ Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein Q NP_391536.1 3759702 R 224308 CDS NP_391537.1 16080709 936956 3760694..3761185 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12793527; Product type pe : enzyme; phosphinothricin acetyltransferase YwnH 3761185 ywnH 936956 ywnH Bacillus subtilis subsp. subtilis str. 168 phosphinothricin acetyltransferase YwnH NP_391537.1 3760694 D 224308 CDS NP_391538.1 16080710 936941 3761182..3761700 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3761700 ywnG 936941 ywnG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391538.1 3761182 D 224308 CDS NP_391539.1 16080711 936942 complement(3761987..3762421) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3762421 ywnF 936942 ywnF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391539.1 3761987 R 224308 CDS NP_391540.1 16080712 936957 3762664..3764112 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme; cardiolipin synthase 3764112 clsA 936957 clsA Bacillus subtilis subsp. subtilis str. 168 cardiolipin synthase NP_391540.1 3762664 D 224308 CDS NP_391541.1 16080713 936962 complement(3764133..3764906) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10200972, 11581256; Product type r: regulator; HTH-type transcriptional activator mta 3764906 mta 936962 mta Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional activator mta NP_391541.1 3764133 R 224308 CDS NP_391542.1 16080714 936950 3765051..3765434 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3765434 ywnC 936950 ywnC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391542.1 3765051 D 224308 CDS NP_391543.1 16080715 936961 complement(3765469..3766110) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3766110 ywnB 936961 ywnB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391543.1 3765469 R 224308 CDS NP_391544.1 16080716 936952 complement(3766178..3766579) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; HTH-type transcriptional regulator YwnA 3766579 ywnA 936952 ywnA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwnA NP_391544.1 3766178 R 224308 CDS NP_391545.1 16080717 936958 complement(3766714..3768423) 1 NC_000964.3 ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; urease subunit alpha 3768423 ureC 936958 ureC Bacillus subtilis subsp. subtilis str. 168 urease subunit alpha NP_391545.1 3766714 R 224308 CDS NP_391546.1 16080718 936967 complement(3768420..3768794) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12401490, 16199586, 9287005; Product type e: enzyme; urease subunit beta 3768794 ureB 936967 ureB Bacillus subtilis subsp. subtilis str. 168 urease subunit beta NP_391546.1 3768420 R 224308 CDS NP_391547.1 16080719 936968 complement(3768791..3769108) 1 NC_000964.3 UreA, with UreB and UreC catalyzes the hydrolysis of urea into ammonia and carbon dioxide; nickel metalloenzyme; accessory proteins UreD, UreE, UreF, and UreG are necessary for assembly of the metallocenter; urease subunit gamma 3769108 ureA 936968 ureA Bacillus subtilis subsp. subtilis str. 168 urease subunit gamma NP_391547.1 3768791 R 224308 CDS NP_391548.1 16080720 936969 complement(3770104..3770292) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10376822, 11988534; Product type f: factor; stress response protein CsbD 3770292 csbD 936969 csbD Bacillus subtilis subsp. subtilis str. 168 stress response protein CsbD NP_391548.1 3770104 R 224308 CDS NP_391549.2 255767786 936974 complement(3770365..3770865) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3770865 ywmF 936974 ywmF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391549.2 3770365 R 224308 CDS NP_391550.1 16080722 936963 complement(3771000..3772133) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629174, 12875849, 9843420; Product type e: enzyme; response regulator aspartate phosphatase B 3772133 rapB 936963 rapB Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase B NP_391550.1 3771000 R 224308 CDS NP_391551.1 16080723 936982 complement(3772325..3773350) 1 NC_000964.3 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z; cyclic pyranopterin monophosphate synthase 3773350 moaA 936982 moaA Bacillus subtilis subsp. subtilis str. 168 cyclic pyranopterin monophosphate synthase NP_391551.1 3772325 R 224308 CDS NP_391552.1 16080724 936976 complement(3773366..3774154) 1 NC_000964.3 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth; protein FdhD homolog 3774154 fdhD 936976 fdhD Bacillus subtilis subsp. subtilis str. 168 protein FdhD homolog NP_391552.1 3773366 R 224308 CDS NP_391553.1 16080725 936977 complement(3774400..3774561) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3774561 ywmE 936977 ywmE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391553.1 3774400 R 224308 CDS NP_391554.1 16080726 936987 complement(3774655..3775329) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3775329 ywmD 936987 ywmD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391554.1 3774655 R 224308 CDS NP_391555.1 16080727 936990 complement(3775653..3776336) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3776336 ywmC 936990 ywmC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391555.1 3775653 R 224308 CDS NP_391556.1 16080728 936979 complement(3776722..3777753) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15752199, 16959571, 17376078; Product type cp: cell process; stage II sporulation protein D 3777753 spoIID 936979 spoIID Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein D NP_391556.1 3776722 R 224308 CDS NP_391557.1 16080729 936980 complement(3777949..3779259) 1 NC_000964.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 3779259 murAA 936980 murAA Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 NP_391557.1 3777949 R 224308 CDS NP_391558.1 16080730 936983 complement(3779293..3780033) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3780033 ywmB 936983 ywmB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391558.1 3779293 R 224308 CDS NP_391559.1 16080731 936986 complement(3780162..3780392) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3780392 ywzB 936986 ywzB Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391559.1 3780162 R 224308 CDS NP_391560.1 16080732 936991 3780562..3781035 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3781035 ywmA 936991 ywmA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391560.1 3780562 D 224308 CDS NP_391561.1 16080733 936994 complement(3781069..3781467) 1 NC_000964.3 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; ATP synthase epsilon chain 3781467 atpC 936994 atpC Bacillus subtilis subsp. subtilis str. 168 ATP synthase epsilon chain NP_391561.1 3781069 R 224308 CDS NP_391562.1 16080734 936992 complement(3781491..3782912) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; ATP synthase subunit beta 3782912 atpD 936992 atpD Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit beta NP_391562.1 3781491 R 224308 CDS NP_391563.1 16080735 936989 complement(3782938..3783801) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; ATP synthase gamma chain 3783801 atpG 936989 atpG Bacillus subtilis subsp. subtilis str. 168 ATP synthase gamma chain NP_391563.1 3782938 R 224308 CDS NP_391564.1 16080736 936995 complement(3783878..3785386) 1 NC_000964.3 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; ATP synthase subunit alpha 3785386 atpA 936995 atpA Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit alpha NP_391564.1 3783878 R 224308 CDS NP_391565.1 16080737 936997 complement(3785403..3785948) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; ATP synthase subunit delta 3785948 atpH 936997 atpH Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit delta NP_391565.1 3785403 R 224308 CDS NP_391566.1 16080738 936998 complement(3785945..3786457) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; ATP synthase subunit b 3786457 atpF 936998 atpF Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit b NP_391566.1 3785945 R 224308 CDS NP_391567.1 16080739 936999 complement(3786620..3786832) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; ATP synthase subunit c 3786832 atpE 936999 atpE Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit c NP_391567.1 3786620 R 224308 CDS NP_391568.1 16080740 937004 complement(3786878..3787612) 1 NC_000964.3 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; ATP synthase subunit a 3787612 atpB 937004 atpB Bacillus subtilis subsp. subtilis str. 168 ATP synthase subunit a NP_391568.1 3786878 R 224308 CDS NP_391569.1 16080741 937003 complement(3787620..3788003) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12917488, 15849754, 16850406; Product type t: transporter; ATP synthase protein I 3788003 atpI 937003 atpI Bacillus subtilis subsp. subtilis str. 168 ATP synthase protein I NP_391569.1 3787620 R 224308 CDS NP_391570.1 16080742 937006 complement(3788426..3789055) 1 NC_000964.3 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 3789055 upp 937006 upp Bacillus subtilis subsp. subtilis str. 168 uracil phosphoribosyltransferase NP_391570.1 3788426 R 224308 CDS NP_391571.1 16080743 937015 complement(3789190..3790437) 1 NC_000964.3 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 3790437 glyA 937015 glyA Bacillus subtilis subsp. subtilis str. 168 serine hydroxymethyltransferase NP_391571.1 3789190 R 224308 CDS NP_391572.1 16080744 937007 complement(3790644..3791186) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15995210; hypothetical protein 3791186 ywlG 937007 ywlG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391572.1 3790644 R 224308 CDS NP_391573.1 16080745 937014 complement(3791199..3791648) 1 NC_000964.3 catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; sugar phosphate isomerase YwlF 3791648 ywlF 937014 ywlF Bacillus subtilis subsp. subtilis str. 168 sugar phosphate isomerase YwlF NP_391573.1 3791199 R 224308 CDS NP_391574.1 16080746 937021 complement(3791805..3792257) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15995210; Product type e: enzyme; low molecular weight protein-tyrosine-phosphatase YwlE 3792257 ywlE 937021 ywlE Bacillus subtilis subsp. subtilis str. 168 low molecular weight protein-tyrosine-phosphatase YwlE NP_391574.1 3791805 R 224308 CDS NP_391575.1 16080747 937022 complement(3792333..3792890) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3792890 ywlD 937022 ywlD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391575.1 3792333 R 224308 CDS NP_391576.1 16080748 937023 complement(3792969..3794009) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12682299, 16014871, 16890019, 17005971; Product type pf: factor; tRNA threonylcarbamoyladenosine biosynthesis protein YwlC 3794009 ywlC 937023 ywlC Bacillus subtilis subsp. subtilis str. 168 tRNA threonylcarbamoyladenosine biosynthesis protein YwlC NP_391576.1 3792969 R 224308 CDS NP_391577.1 16080749 937028 complement(3794166..3794609) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3794609 ywlB 937028 ywlB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391577.1 3794166 R 224308 CDS NP_391578.1 16080750 937017 complement(3794676..3795350) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15044948, 16824103; Product type e: enzyme; stage II sporulation protein R 3795350 spoIIR 937017 spoIIR Bacillus subtilis subsp. subtilis str. 168 stage II sporulation protein R NP_391578.1 3794676 R 224308 CDS NP_391579.1 16080751 938509 3795491..3795853 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3795853 ywlA 938509 ywlA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391579.1 3795491 D 224308 CDS NP_391580.1 16080752 938510 complement(3795870..3796157) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3796157 ywkF 938510 ywkF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391580.1 3795870 R 224308 CDS NP_391581.1 16080753 938511 complement(3796217..3797083) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 16014871, 16364916; Product type e: enzyme; release factor glutamine methyltransferase 3797083 prmC 938511 prmC Bacillus subtilis subsp. subtilis str. 168 release factor glutamine methyltransferase NP_391581.1 3796217 R 224308 CDS NP_391582.1 16080754 937031 complement(3797085..3798155) 1 NC_000964.3 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 3798155 prfA 937031 prfA Bacillus subtilis subsp. subtilis str. 168 peptide chain release factor 1 NP_391582.1 3797085 R 224308 CDS NP_391583.1 16080755 937039 3798281..3798667 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3798667 ywkD 937039 ywkD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391583.1 3798281 D 224308 CDS NP_391584.1 16080756 937043 3798789..3799343 1 NC_000964.3 remodeling and anchoring of the chromosome protein; in Bacillus subtilis this protein functions in polar chromosome segregation during sporulation; binds inverted sequence motifs called ram along the chromosome; condenses DNA via RacA-RacA interactions; chromosome-anchoring protein RacA 3799343 racA 937043 racA Bacillus subtilis subsp. subtilis str. 168 chromosome-anchoring protein RacA NP_391584.1 3798789 D 224308 CDS NP_391585.1 16080757 936875 complement(3799377..3800336) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12949160, 15849754, 16850406; Product type pt: transporter; transporter 3800336 ywkB 936875 ywkB Bacillus subtilis subsp. subtilis str. 168 transporter NP_391585.1 3799377 R 224308 CDS NP_391586.1 16080758 937045 complement(3800418..3802166) 1 NC_000964.3 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate; NAD-dependent malic enzyme 2 3802166 ywkA 937045 ywkA Bacillus subtilis subsp. subtilis str. 168 NAD-dependent malic enzyme 2 NP_391586.1 3800418 R 224308 CDS NP_391587.1 16080759 937033 complement(3802405..3802992) 1 NC_000964.3 catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 3802992 tdk 937033 tdk Bacillus subtilis subsp. subtilis str. 168 thymidine kinase NP_391587.1 3802405 R 224308 CDS NP_391588.1 16080760 937034 complement(3803081..3803281) 1 NC_000964.3 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 3803281 rpmE 937034 rpmE Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L31 NP_391588.1 3803081 R 224308 CDS NP_391589.2 255767787 937042 complement(3803400..3804683) 1 NC_000964.3 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 3804683 rho 937042 rho Bacillus subtilis subsp. subtilis str. 168 transcription termination factor Rho NP_391589.2 3803400 R 224308 CDS NP_391590.1 16080762 937035 complement(3805090..3806055) 1 NC_000964.3 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose-1,6-bisphosphatase class 2 3806055 glpX 937035 glpX Bacillus subtilis subsp. subtilis str. 168 fructose-1,6-bisphosphatase class 2 NP_391590.1 3805090 R 224308 CDS NP_391591.2 255767788 937038 complement(3806086..3807375) 1 NC_000964.3 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 3807375 murAB 937038 murAB Bacillus subtilis subsp. subtilis str. 168 UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 NP_391591.2 3806086 R 224308 CDS NP_391592.3 255767789 938462 complement(3807754..3808392) 1 NC_000964.3 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; transaldolase 3808392 ywjH 938462 ywjH Bacillus subtilis subsp. subtilis str. 168 transaldolase NP_391592.3 3807754 R 224308 CDS NP_391593.1 16080765 937040 complement(3808512..3809369) 1 NC_000964.3 catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; induced by anaerobic conditions in Bacillus subtilis; fructose-bisphosphate aldolase 3809369 fbaA 937040 fbaA Bacillus subtilis subsp. subtilis str. 168 fructose-bisphosphate aldolase NP_391593.1 3808512 R 224308 CDS NP_391594.1 16080766 937041 complement(3809550..3809924) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11934609, 16788205, 8257105; Product type r: regulator; sporulation initiation phosphotransferase F 3809924 spo0F 937041 spo0F Bacillus subtilis subsp. subtilis str. 168 sporulation initiation phosphotransferase F NP_391594.1 3809550 R 224308 CDS NP_391595.1 16080767 938459 3810090..3810611 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3810611 ywjG 938459 ywjG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391595.1 3810090 D 224308 CDS NP_391596.1 16080768 937044 complement(3810693..3812300) 1 NC_000964.3 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthase 3812300 pyrG 937044 pyrG Bacillus subtilis subsp. subtilis str. 168 CTP synthase NP_391596.1 3810693 R 224308 CDS NP_391597.1 16080769 937046 complement(3812542..3813063) 1 NC_000964.3 participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 3813063 rpoE 937046 rpoE Bacillus subtilis subsp. subtilis str. 168 DNA-directed RNA polymerase subunit delta NP_391597.1 3812542 R 224308 CDS NP_391598.1 16080770 938457 complement(3813246..3814385) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17189250; Product type e: enzyme; acyl-CoA dehydrogenase 3814385 acdA 938457 acdA Bacillus subtilis subsp. subtilis str. 168 acyl-CoA dehydrogenase NP_391598.1 3813246 R 224308 CDS NP_391599.1 16080771 938461 complement(3814382..3816499) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17189250; Product type pe : enzyme; hypothetical protein 3816499 fadF 938461 fadF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391599.1 3814382 R 224308 CDS NP_391600.1 16080772 938460 3816654..3817850 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 18820022; Product type e: enzyme; cardiolipin synthetase 3817850 clsB 938460 clsB Bacillus subtilis subsp. subtilis str. 168 cardiolipin synthetase NP_391600.1 3816654 D 224308 CDS NP_391601.1 16080773 938195 3817863..3818825 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8614629; Product type pe : enzyme; UV DNA damage endonuclease 3818825 uvsE 938195 uvsE Bacillus subtilis subsp. subtilis str. 168 UV DNA damage endonuclease NP_391601.1 3817863 D 224308 CDS NP_391602.1 16080774 938458 3818906..3819178 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3819178 ywjC 938458 ywjC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391602.1 3818906 D 224308 CDS NP_391603.1 16080775 938455 complement(3819220..3819744) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12354229; Product type pe : enzyme; hypothetical protein 3819744 ywjB 938455 ywjB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391603.1 3819220 R 224308 CDS NP_391604.1 16080776 937049 complement(3819754..3821481) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12119303, 12354229; Product type pt: transporter; ABC transporter ATP-binding protein 3821481 ywjA 937049 ywjA Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391604.1 3819754 R 224308 CDS NP_391605.1 16080777 938453 complement(3821570..3823072) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973018, 15743965; Product type e: enzyme; cardiolipin synthase YwiE 3823072 ywiE 938453 ywiE Bacillus subtilis subsp. subtilis str. 168 cardiolipin synthase YwiE NP_391605.1 3821570 R 224308 CDS NP_391606.1 16080778 938454 complement(3823558..3824229) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 15849754, 16850406, 7557333, 7860592, 8846791; Product type e : enzyme; nitrate reductase gamma chain 3824229 narI 938454 narI Bacillus subtilis subsp. subtilis str. 168 nitrate reductase gamma chain NP_391606.1 3823558 R 224308 CDS NP_391607.1 16080779 937051 complement(3824226..3824780) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase molybdenum cofactor assembly chaperone NarJ 3824780 narJ 937051 narJ Bacillus subtilis subsp. subtilis str. 168 nitrate reductase molybdenum cofactor assembly chaperone NarJ NP_391607.1 3824226 R 224308 CDS NP_391608.1 16080780 937047 complement(3824806..3826269) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase beta chain 3826269 narH 937047 narH Bacillus subtilis subsp. subtilis str. 168 nitrate reductase beta chain NP_391608.1 3824806 R 224308 CDS NP_391609.2 255767790 938358 complement(3826259..3829945) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 11289299, 7557333, 7860592, 8846791; Product type e: enzyme; nitrate reductase alpha chain 3829945 narG 938358 narG Bacillus subtilis subsp. subtilis str. 168 nitrate reductase alpha chain NP_391609.2 3826259 R 224308 CDS NP_391610.1 16080782 937058 complement(3830141..3830617) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10809684, 11698370, 16428414; Product type r: regulator; transcription regulator ArfM 3830617 arfM 937058 arfM Bacillus subtilis subsp. subtilis str. 168 transcription regulator ArfM NP_391610.1 3830141 R 224308 CDS NP_391611.1 16080783 937048 3830761..3831480 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16428414, 16850406; Product type pm: membrane component; hypothetical protein 3831480 ywiC 937048 ywiC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391611.1 3830761 D 224308 CDS NP_391612.1 16080784 937050 complement(3831512..3832228) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16796679, 8682783, 8846791; Product type r: regulator; anaerobic regulatory protein 3832228 fnr 937050 fnr Bacillus subtilis subsp. subtilis str. 168 anaerobic regulatory protein NP_391612.1 3831512 R 224308 CDS NP_391613.2 255767791 937055 complement(3832327..3833514) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16796679, 16850406, 8682783, 8846791; Product type t: transporter; nitrite extrusion protein 3833514 narK 937055 narK Bacillus subtilis subsp. subtilis str. 168 nitrite extrusion protein NP_391613.2 3832327 R 224308 CDS NP_391614.1 16080786 937054 complement(3833650..3835320) 1 NC_000964.3 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginine--tRNA ligase 3835320 argS 937054 argS Bacillus subtilis subsp. subtilis str. 168 arginine--tRNA ligase NP_391614.1 3833650 R 224308 CDS NP_391615.1 16080787 937056 complement(3835317..3835745) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; beta-barrel protein YwiB 3835745 ywiB 937056 ywiB Bacillus subtilis subsp. subtilis str. 168 beta-barrel protein YwiB NP_391615.1 3835317 R 224308 CDS NP_391616.1 16080788 938512 3836058..3836189 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12696888, 15743949, 16095584, 17213266; Product type f: factor; subtilosin-A 3836189 sboA 938512 sboA Bacillus subtilis subsp. subtilis str. 168 subtilosin-A NP_391616.1 3836058 D 224308 CDS YP_054594.1 50812300 2914193 3836146..3836298 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949; Product type pf : factor; bacteriocin-like protein SboX 3836298 sboX 2914193 sboX Bacillus subtilis subsp. subtilis str. 168 bacteriocin-like protein SboX YP_054594.1 3836146 D 224308 CDS NP_391617.1 16080789 937059 3836323..3837669 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15066831, 15743949; Product type pe: enzyme; antilisterial bacteriocin subtilosin biosynthesis protein AlbA 3837669 albA 937059 albA Bacillus subtilis subsp. subtilis str. 168 antilisterial bacteriocin subtilosin biosynthesis protein AlbA NP_391617.1 3836323 D 224308 CDS NP_391618.1 16080790 937057 3837682..3837843 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15743949; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbB 3837843 albB 937057 albB Bacillus subtilis subsp. subtilis str. 168 antilisterial bacteriocin subtilosin biosynthesis protein AlbB NP_391618.1 3837682 D 224308 CDS NP_391619.1 16080791 937068 3837840..3838559 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pt: transporter; ABC transporter ATP-binding protein 3838559 albC 937068 albC Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391619.1 3837840 D 224308 CDS NP_391620.1 16080792 937053 3838552..3839862 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949, 15849754, 16850406; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbD 3839862 albD 937053 albD Bacillus subtilis subsp. subtilis str. 168 antilisterial bacteriocin subtilosin biosynthesis protein AlbD NP_391620.1 3838552 D 224308 CDS NP_391621.1 16080793 938514 3839852..3841012 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme; antilisterial bacteriocin subtilosin biosynthesis protein AlbE 3841012 albE 938514 albE Bacillus subtilis subsp. subtilis str. 168 antilisterial bacteriocin subtilosin biosynthesis protein AlbE NP_391621.1 3839852 D 224308 CDS NP_391622.1 16080794 938515 3841017..3842297 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15743949; Product type pe: enzyme; zinc protease AlbF 3842297 albF 938515 albF Bacillus subtilis subsp. subtilis str. 168 zinc protease AlbF NP_391622.1 3841017 D 224308 CDS NP_391623.1 16080795 937060 3842294..3842995 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10809709, 15066831, 15849754, 16850406; Product type pm: membrane component; antilisterial bacteriocin subtilosin biosynthesis protein AlbG 3842995 albG 937060 albG Bacillus subtilis subsp. subtilis str. 168 antilisterial bacteriocin subtilosin biosynthesis protein AlbG NP_391623.1 3842294 D 224308 CDS NP_391624.1 16080796 937067 complement(3843001..3844377) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3844377 ywhL 937067 ywhL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391624.1 3843001 R 224308 CDS NP_391625.1 16080797 937087 complement(3844416..3845771) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12073041; Product type f: factor; hypothetical protein 3845771 ywhK 937087 ywhK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391625.1 3844416 R 224308 CDS NP_391626.1 16080798 936725 3846001..3847146 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type e: enzyme; response regulator aspartate phosphatase F 3847146 rapF 936725 rapF Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase F NP_391626.1 3846001 D 224308 CDS NP_391627.1 16080799 936721 3847130..3847249 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15968044, 16816200; Product type f: factor; phosphatase RapF inhibitor 3847249 phrF 936721 phrF Bacillus subtilis subsp. subtilis str. 168 phosphatase RapF inhibitor NP_391627.1 3847130 D 224308 CDS NP_391628.1 16080800 937183 3847348..3847821 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 3847821 ywhH 937183 ywhH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391628.1 3847348 D 224308 CDS NP_391629.1 16080801 937205 complement(3847853..3848725) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10931887, 9723923; Product type e: enzyme; agmatinase 3848725 speB 937205 speB Bacillus subtilis subsp. subtilis str. 168 agmatinase NP_391629.1 3847853 R 224308 CDS NP_391630.1 16080802 937075 complement(3848786..3849616) 1 NC_000964.3 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 3849616 speE 937075 speE Bacillus subtilis subsp. subtilis str. 168 spermidine synthase NP_391630.1 3848786 R 224308 CDS NP_391631.2 255767792 937200 3849818..3851893 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10767540, 11567005; Product type cp: cell process; penicillin-binding protein 2D 3851893 pbpG 937200 pbpG Bacillus subtilis subsp. subtilis str. 168 penicillin-binding protein 2D NP_391631.2 3849818 D 224308 CDS NP_391632.1 16080804 937100 complement(3852186..3852704) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3852704 ywhD 937100 ywhD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391632.1 3852186 R 224308 CDS NP_391633.1 16080805 937099 complement(3852718..3853377) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; zinc metalloprotease YwhC 3853377 ywhC 937099 ywhC Bacillus subtilis subsp. subtilis str. 168 zinc metalloprotease YwhC NP_391633.1 3852718 R 224308 CDS NP_391634.1 16080806 937098 3853486..3853674 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14624569, 14730980, 15301547, 17902707; Product type e: enzyme; 4-oxalocrotonate tautomerase 3853674 ywhB 937098 ywhB Bacillus subtilis subsp. subtilis str. 168 4-oxalocrotonate tautomerase NP_391634.1 3853486 D 224308 CDS NP_391635.1 16080807 937081 complement(3853717..3854136) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwhA 3854136 ywhA 937081 ywhA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwhA NP_391635.1 3853717 R 224308 CDS NP_391636.2 255767793 937135 complement(3854256..3856172) 1 NC_000964.3 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); Bacillus have two copies of the threonyl-tRNA synthetase, threonine starvation induces both proteins; threonine--tRNA ligase 2 3856172 thrZ 937135 thrZ Bacillus subtilis subsp. subtilis str. 168 threonine--tRNA ligase 2 NP_391636.2 3854256 R 224308 CDS NP_391637.1 16080809 937101 complement(3857017..3858417) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11104814, 15849754, 16850406; Product type t: transporter; methylenomycin A resistance protein 3858417 mmr 937101 mmr Bacillus subtilis subsp. subtilis str. 168 methylenomycin A resistance protein NP_391637.1 3857017 R 224308 CDS NP_391638.1 16080810 937074 complement(3858417..3858887) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16885456; Product type pr : regulator; HTH-type transcriptional regulator YwgB 3858887 ywgB 937074 ywgB Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwgB NP_391638.1 3858417 R 224308 CDS NP_391639.1 16080811 937077 complement(3858999..3859499) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250; hypothetical protein 3859499 ywgA 937077 ywgA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391639.1 3858999 R 224308 CDS NP_391640.1 16080812 937082 complement(3859535..3860836) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16855250; Product type pe : enzyme; hypothetical protein 3860836 ywfO 937082 ywfO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391640.1 3859535 R 224308 CDS NP_391641.1 16080813 937093 complement(3860998..3861222) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250; hypothetical protein 3861222 ywzC 937093 ywzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391641.1 3860998 R 224308 CDS NP_391642.1 16080814 937126 3861437..3862213 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10629188, 16497325; Product type cp: cell process; prespore-specific transcriptional regulator RsfA 3862213 rsfA 937126 rsfA Bacillus subtilis subsp. subtilis str. 168 prespore-specific transcriptional regulator RsfA NP_391642.1 3861437 D 224308 CDS NP_391643.1 16080815 937972 complement(3862357..3863247) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3863247 ywfM 937972 ywfM Bacillus subtilis subsp. subtilis str. 168 transporter NP_391643.1 3862357 R 224308 CDS NP_391644.1 16080816 937083 complement(3863415..3864260) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; octanoyl-[GcvH]:protein N-octanoyltransferase 3864260 ywfL 937083 ywfL Bacillus subtilis subsp. subtilis str. 168 octanoyl-[GcvH]:protein N-octanoyltransferase NP_391644.1 3863415 R 224308 CDS NP_391645.1 16080817 936502 complement(3864309..3865208) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12169591; Product type r: regulator; HTH-type transcriptional regulator CysL 3865208 cysL 936502 cysL Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator CysL NP_391645.1 3864309 R 224308 CDS NP_391646.1 16080818 936581 complement(3865355..3866326) 1 NC_000964.3 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphate acetyltransferase 3866326 eutD 936581 eutD Bacillus subtilis subsp. subtilis str. 168 phosphate acetyltransferase NP_391646.1 3865355 R 224308 CDS NP_391647.2 161511066 936512 3866611..3867360 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317589, 16403788; Product type pe: enzyme; heme peroxidase 3867360 ywfI 936512 ywfI Bacillus subtilis subsp. subtilis str. 168 heme peroxidase NP_391647.2 3866611 D 224308 CDS NP_391648.1 16080820 937215 3867493..3868272 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825; Product type e: enzyme; bacilysin biosynthesis oxidoreductase YwfH 3868272 ywfH 937215 ywfH Bacillus subtilis subsp. subtilis str. 168 bacilysin biosynthesis oxidoreductase YwfH NP_391648.1 3867493 D 224308 CDS NP_391649.1 16080821 937157 complement(3868287..3869486) 1 NC_000964.3 produces methionine from 2-keto-4-methylthiobutyrate and glutamine in vitro; mutations do not affect methionine salvage in vivo however; aspartate aminotransferase 3869486 ywfG 937157 ywfG Bacillus subtilis subsp. subtilis str. 168 aspartate aminotransferase NP_391649.1 3868287 R 224308 CDS NP_391650.1 16080822 937161 complement(3869487..3870671) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023, 15849754, 16850406; Product type t: transporter; bacilysin exporter BacE 3870671 bacE 937161 bacE Bacillus subtilis subsp. subtilis str. 168 bacilysin exporter BacE NP_391650.1 3869487 R 224308 CDS NP_391651.1 16080823 937214 complement(3870668..3872086) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15609023, 16030213; Product type e: enzyme; alanine-anticapsin ligase BacD 3872086 bacD 937214 bacD Bacillus subtilis subsp. subtilis str. 168 alanine-anticapsin ligase BacD NP_391651.1 3870668 R 224308 CDS NP_391652.1 16080824 937065 complement(3872105..3872872) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme; bacilysin biosynthesis oxidoreductase 3872872 bacC 937065 bacC Bacillus subtilis subsp. subtilis str. 168 bacilysin biosynthesis oxidoreductase NP_391652.1 3872105 R 224308 CDS NP_391653.1 16080825 937084 complement(3872869..3873576) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 14697267, 15609023, 15628860; Product type e: enzyme; bacilysin biosynthesis protein BacB 3873576 bacB 937084 bacB Bacillus subtilis subsp. subtilis str. 168 bacilysin biosynthesis protein BacB NP_391653.1 3872869 R 224308 CDS NP_391654.1 16080826 937216 complement(3873566..3874180) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12372825, 15609023; Product type e: enzyme; bacilysin biosynthesis protein BacA 3874180 bacA 937216 bacA Bacillus subtilis subsp. subtilis str. 168 bacilysin biosynthesis protein BacA NP_391654.1 3873566 R 224308 CDS NP_391655.1 16080827 937061 complement(3874332..3875570) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15609023, 15849754, 16850406; Product type pt: transporter; MFS transporter 3875570 ywfA 937061 ywfA Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391655.1 3874332 R 224308 CDS NP_391656.1 16080828 938495 complement(3875780..3877192) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 7540694, 8113162; Product type t: transporter; amino acid permease RocC 3877192 rocC 938495 rocC Bacillus subtilis subsp. subtilis str. 168 amino acid permease RocC NP_391656.1 3875780 R 224308 CDS NP_391657.1 16080829 937220 complement(3877192..3878892) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 8113162; Product type pe : enzyme; arginine utilization protein RocB 3878892 rocB 937220 rocB Bacillus subtilis subsp. subtilis str. 168 arginine utilization protein RocB NP_391657.1 3877192 R 224308 CDS NP_391658.1 16080830 937222 complement(3878966..3880513) 1 NC_000964.3 catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate; 1-pyrroline-5-carboxylate dehydrogenase 3880513 rocA 937222 rocA Bacillus subtilis subsp. subtilis str. 168 1-pyrroline-5-carboxylate dehydrogenase NP_391658.1 3878966 R 224308 CDS NP_391659.2 255767794 937066 complement(3880740..3882014) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10468601, 12634342, 15150224, 17183217, 17608797, 18326565; Product type e : enzyme; catabolic NAD-specific glutamate dehydrogenase RocG 3882014 rocG 937066 rocG Bacillus subtilis subsp. subtilis str. 168 catabolic NAD-specific glutamate dehydrogenase RocG NP_391659.2 3880740 R 224308 CDS NP_391660.1 16080832 937223 complement(3882191..3882655) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15187182; Product type ph: phenotype; hypothetical protein 3882655 yweA 937223 yweA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391660.1 3882191 R 224308 CDS YP_054595.1 50812301 2914201 complement(3882979..3883434) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; spore coat polysaccharide biosynthesis protein SpsL 3883434 spsL 2914201 spsL Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsL YP_054595.1 3882979 R 224308 CDS NP_391661.3 255767795 937225 complement(3883427..3884278) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process; spore coat polysaccharide biosynthesis protein SpsK 3884278 spsK 937225 spsK Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsK NP_391661.3 3883427 R 224308 CDS NP_391662.1 16080834 937227 complement(3884292..3885239) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; dTDP-glucose 4,6-dehydratase 3885239 spsJ 937227 spsJ Bacillus subtilis subsp. subtilis str. 168 dTDP-glucose 4,6-dehydratase NP_391662.1 3884292 R 224308 CDS NP_391663.1 16080835 937229 complement(3885239..3885979) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; dTDP-glucose pyrophosphorylase 3885979 spsI 937229 spsI Bacillus subtilis subsp. subtilis str. 168 dTDP-glucose pyrophosphorylase NP_391663.1 3885239 R 224308 CDS NP_391664.1 16080836 937230 complement(3886004..3887023) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsG 3887023 spsG 937230 spsG Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsG NP_391664.1 3886004 R 224308 CDS NP_391665.2 255767796 937232 complement(3887026..3887748) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsF 3887748 spsF 937232 spsF Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsF NP_391665.2 3887026 R 224308 CDS NP_391666.1 16080838 937233 complement(3887741..3888862) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15774001; Product type pe : enzyme; spore coat polysaccharide biosynthesis protein SpsE 3888862 spsE 937233 spsE Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsE NP_391666.1 3887741 R 224308 CDS NP_391667.1 16080839 937250 complement(3888862..3889731) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsD 3889731 spsD 937250 spsD Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsD NP_391667.1 3888862 R 224308 CDS NP_391668.1 16080840 937234 complement(3889732..3890901) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14602648; Product type pe : enzyme; spore coat polysaccharide biosynthesis protein SpsC 3890901 spsC 937234 spsC Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsC NP_391668.1 3889732 R 224308 CDS NP_391669.2 255767797 937239 complement(3890922..3892346) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; spore coat polysaccharide biosynthesis protein SpsB 3892346 spsB 937239 spsB Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsB NP_391669.2 3890922 R 224308 CDS NP_391670.1 16080842 937253 complement(3892351..3893121) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10350455, 11042447, 11733986; Product type e: enzyme; spore coat polysaccharide biosynthesis protein SpsA 3893121 spsA 937253 spsA Bacillus subtilis subsp. subtilis str. 168 spore coat polysaccharide biosynthesis protein SpsA NP_391670.1 3892351 R 224308 CDS NP_391671.1 16080843 937241 3893441..3893986 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12644503; Product type cp: cell process; spore coat protein GerQ 3893986 ywdL 937241 ywdL Bacillus subtilis subsp. subtilis str. 168 spore coat protein GerQ NP_391671.1 3893441 D 224308 CDS NP_391672.2 255767798 937242 complement(3894030..3894401) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3894401 ywdK 937242 ywdK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391672.2 3894030 R 224308 CDS NP_391673.2 255767799 937261 complement(3894463..3895785) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; purine permease YwdJ 3895785 ywdJ 937261 ywdJ Bacillus subtilis subsp. subtilis str. 168 purine permease YwdJ NP_391673.2 3894463 R 224308 CDS NP_391674.2 255767800 937251 complement(3895805..3896161) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3896161 ywdI 937251 ywdI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391674.2 3895805 R 224308 CDS NP_391675.2 255767801 937252 3896290..3897660 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase YwdH 3897660 ywdH 937252 ywdH Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase YwdH NP_391675.2 3896290 D 224308 CDS NP_391676.1 16080848 937265 complement(3897685..3898362) 1 NC_000964.3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 3898362 ung 937265 ung Bacillus subtilis subsp. subtilis str. 168 uracil-DNA glycosylase NP_391676.1 3897685 R 224308 CDS NP_391677.1 16080849 937259 complement(3898376..3899182) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; glycosyltransferase YwdF 3899182 ywdF 937259 ywdF Bacillus subtilis subsp. subtilis str. 168 glycosyltransferase YwdF NP_391677.1 3898376 R 224308 CDS NP_391678.1 16080850 937260 complement(3899272..3899805) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3899805 ywdE 937260 ywdE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391678.1 3899272 R 224308 CDS NP_391679.2 255767802 937267 complement(3899853..3900488) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3900488 ywdD 937267 ywdD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391679.2 3899853 R 224308 CDS YP_003097793.1 255767803 8303176 complement(3900481..3900819) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; DNA-binding protein YwzG 3900819 ywzG 8303176 ywzG Bacillus subtilis subsp. subtilis str. 168 DNA-binding protein YwzG YP_003097793.1 3900481 R 224308 CDS NP_391681.1 16080853 937262 3900963..3901778 1 NC_000964.3 catalyzes the phosphorylation of three vitamin B6 precursors, pyridoxal, pyridoxine and pyridoxamine; pyridoxine kinase 3901778 thiD 937262 thiD Bacillus subtilis subsp. subtilis str. 168 pyridoxine kinase NP_391681.1 3900963 D 224308 CDS NP_391682.1 16080854 937276 complement(3901868..3902116) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3902116 ywdA 937276 ywdA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391682.1 3901868 R 224308 CDS NP_391683.2 255767804 937277 complement(3902210..3903649) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 3100393; Product type e: enzyme; sucrose-6-phosphate hydrolase 3903649 sacA 937277 sacA Bacillus subtilis subsp. subtilis str. 168 sucrose-6-phosphate hydrolase NP_391683.2 3902210 R 224308 CDS NP_391684.3 255767805 937266 complement(3903646..3905031) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 15849754, 16850406, 3122206; Product type t: transporter; PTS system sucrose-specific EIIBC component 3905031 sacP 937266 sacP Bacillus subtilis subsp. subtilis str. 168 PTS system sucrose-specific EIIBC component NP_391684.3 3903646 R 224308 CDS NP_391685.1 16080857 937283 3905333..3906103 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15849754, 16207915, 16428414, 16850406; Product type t: transporter; transporter 3906103 ywcJ 937283 ywcJ Bacillus subtilis subsp. subtilis str. 168 transporter NP_391685.1 3905333 D 224308 CDS NP_391686.1 16080858 937284 complement(3906142..3906972) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1577686, 2163394, 8535520, 8702561; Product type r: regulator; SacPA operon antiterminator 3906972 sacT 937284 sacT Bacillus subtilis subsp. subtilis str. 168 SacPA operon antiterminator NP_391686.1 3906142 R 224308 CDS NP_391687.2 255767806 937275 complement(3907012..3907314) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3907314 ywcI 937275 ywcI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391687.2 3907012 R 224308 CDS NP_391688.1 16080860 937291 3907844..3910264 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15205417, 15596354, 16946274, 17666034; Product type e: enzyme; minor extracellular protease vpr 3910264 vpr 937291 vpr Bacillus subtilis subsp. subtilis str. 168 minor extracellular protease vpr NP_391688.1 3907844 D 224308 CDS NP_391689.1 16080861 937286 complement(3910302..3911303) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10913069, 15774866; Product type pe: enzyme; hypothetical protein 3911303 ywcH 937286 ywcH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391689.1 3910302 R 224308 CDS NP_391690.1 16080862 937279 complement(3911477..3912226) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913069, 15774866, 9535080; Product type e: enzyme; FMN reductase 3912226 nfrA 937279 nfrA Bacillus subtilis subsp. subtilis str. 168 FMN reductase NP_391690.1 3911477 R 224308 CDS NP_391691.1 16080863 937294 complement(3912332..3913513) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15612918, 15849754, 16850406, 9622350; Product type f: factor; rod shape-determining protein RodA 3913513 rodA 937294 rodA Bacillus subtilis subsp. subtilis str. 168 rod shape-determining protein RodA NP_391691.1 3912332 R 224308 CDS NP_391692.1 16080864 937296 3914009..3914272 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16159778; Product type f: factor; spore morphogenesis and germination protein YwcE 3914272 ywcE 937296 ywcE Bacillus subtilis subsp. subtilis str. 168 spore morphogenesis and germination protein YwcE NP_391692.1 3914009 D 224308 CDS NP_391693.1 16080865 937285 complement(3914315..3914689) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme; quinol oxidase subunit 4 3914689 qoxD 937285 qoxD Bacillus subtilis subsp. subtilis str. 168 quinol oxidase subunit 4 NP_391693.1 3914315 R 224308 CDS NP_391694.1 16080866 937299 complement(3914691..3915305) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098, 7640280; Product type e: enzyme; quinol oxidase subunit 3 3915305 qoxC 937299 qoxC Bacillus subtilis subsp. subtilis str. 168 quinol oxidase subunit 3 NP_391694.1 3914691 R 224308 CDS NP_391695.1 16080867 937303 complement(3915319..3917268) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 15849754, 16850406, 7495838, 7575098; Product type e : enzyme; quinol oxidase subunit 1 3917268 qoxB 937303 qoxB Bacillus subtilis subsp. subtilis str. 168 quinol oxidase subunit 1 NP_391695.1 3915319 R 224308 CDS NP_391696.2 255767807 937295 complement(3917296..3918261) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10551842, 1316894, 7495838, 7575098; Product type e: enzyme; quinol oxidase subunit 2 3918261 qoxA 937295 qoxA Bacillus subtilis subsp. subtilis str. 168 quinol oxidase subunit 2 NP_391696.2 3917296 R 224308 CDS NP_391697.2 255767808 937305 3918777..3919022 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3919022 ywzA 937305 ywzA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391697.2 3918777 D 224308 CDS NP_391698.2 255767809 937307 complement(3919093..3920634) 1 NC_000964.3 catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase 3920634 galT 937307 galT Bacillus subtilis subsp. subtilis str. 168 galactose-1-phosphate uridylyltransferase NP_391698.2 3919093 R 224308 CDS NP_391699.1 16080871 937297 complement(3920638..3921810) 1 NC_000964.3 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase 3921810 galK 937297 galK Bacillus subtilis subsp. subtilis str. 168 galactokinase NP_391699.1 3920638 R 224308 CDS NP_391700.1 16080872 937313 complement(3921891..3922274) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; membrane protein 3922274 ywcD 937313 ywcD Bacillus subtilis subsp. subtilis str. 168 membrane protein NP_391700.1 3921891 R 224308 CDS NP_391701.2 255767810 937314 complement(3922292..3922963) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwcC 3922963 ywcC 937314 ywcC Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwcC NP_391701.2 3922292 R 224308 CDS YP_003097794.1 255767811 8303165 3923319..3923477 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 18647168; Product type r: regulator; transcriptional regulator SlrA 3923477 slrA 8303165 slrA Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator SlrA YP_003097794.1 3923319 D 224308 CDS NP_391702.1 16080874 937304 3923920..3924228 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 3924228 ywcB 937304 ywcB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391702.1 3923920 D 224308 CDS NP_391703.2 255767812 937320 3924225..3925766 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; symporter 3925766 ywcA 937320 ywcA Bacillus subtilis subsp. subtilis str. 168 symporter NP_391703.2 3924225 D 224308 CDS NP_391704.1 16080876 937309 complement(3925797..3926399) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3926399 ywbO 937309 ywbO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391704.1 3925797 R 224308 CDS NP_391705.1 16080877 937310 complement(3926682..3927932) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15554971, 16672620, 16987175, 18931290; Product type e: enzyme; deferrochelatase/peroxidase EfeN 3927932 efeN 937310 efeN Bacillus subtilis subsp. subtilis str. 168 deferrochelatase/peroxidase EfeN NP_391705.1 3926682 R 224308 CDS NP_391706.1 16080878 937322 complement(3927951..3929108) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 16987175; Product type t: transporter; iron uptake system component EfeM 3929108 efeM 937322 efeM Bacillus subtilis subsp. subtilis str. 168 iron uptake system component EfeM NP_391706.1 3927951 R 224308 CDS NP_391707.2 255767813 938520 complement(3929105..3930550) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 15849754, 16672620, 16850406, 16987175; Product type t : transporter; ferrous iron permease EfeU 3930550 efeU 938520 efeU Bacillus subtilis subsp. subtilis str. 168 ferrous iron permease EfeU NP_391707.2 3929105 R 224308 CDS NP_391708.1 16080880 937316 complement(3930707..3931375) 1 NC_000964.3 Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate synthase 3931375 thiE 937316 thiE Bacillus subtilis subsp. subtilis str. 168 thiamine-phosphate synthase NP_391708.1 3930707 R 224308 CDS NP_391709.1 16080881 938519 complement(3931372..3932190) 1 NC_000964.3 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 3932190 thiM 938519 thiM Bacillus subtilis subsp. subtilis str. 168 hydroxyethylthiazole kinase NP_391709.1 3931372 R 224308 CDS NP_391710.1 16080882 937626 complement(3932198..3933103) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwbI 3933103 ywbI 937626 ywbI Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwbI NP_391710.1 3932198 R 224308 CDS NP_391711.1 16080883 937321 3933209..3933595 1 NC_000964.3 increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation; inhibited by the antiholin-like proteins lrgAB; holin-like protein CidA 3933595 ywbH 937321 ywbH Bacillus subtilis subsp. subtilis str. 168 holin-like protein CidA NP_391711.1 3933209 D 224308 CDS NP_391712.2 255767814 937323 3933577..3934254 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15659658, 15849754, 16850406; Product type r : regulator; hypothetical protein 3934254 lrgB 937323 lrgB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391712.2 3933577 D 224308 CDS NP_391713.1 16080885 937325 3934358..3935557 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 3935557 ywbF 937325 ywbF Bacillus subtilis subsp. subtilis str. 168 transporter NP_391713.1 3934358 D 224308 CDS NP_391714.1 16080886 937326 3935591..3935788 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3935788 ywbE 937326 ywbE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391714.1 3935591 D 224308 CDS NP_391715.1 16080887 937328 complement(3935824..3937014) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; ribosomal RNA large subunit methyltransferase YwbD 3937014 ywbD 937328 ywbD Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA large subunit methyltransferase YwbD NP_391715.1 3935824 R 224308 CDS NP_391716.1 16080888 937329 3937135..3937515 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 3937515 ywbC 937329 ywbC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391716.1 3937135 D 224308 CDS NP_391717.1 16080889 937330 complement(3937553..3938230) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3938230 ywbB 937330 ywbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391717.1 3937553 R 224308 CDS NP_391718.1 16080890 937331 complement(3938307..3939641) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 8990303; Product type pt: transporter; permease IIC component YwbA 3939641 ywbA 937331 ywbA Bacillus subtilis subsp. subtilis str. 168 permease IIC component YwbA NP_391718.1 3938307 R 224308 CDS NP_391719.1 16080891 937332 3939869..3941806 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16553828, 17666034, 1938892, 2116590; Product type e: enzyme; minor extracellular protease epr 3941806 epr 937332 epr Bacillus subtilis subsp. subtilis str. 168 minor extracellular protease epr NP_391719.1 3939869 D 224308 CDS NP_391720.1 16080892 937333 3942234..3943613 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 1400159, 15849754, 16850406, 8535520; Product type r: regulator; negative regulator of SacY activity 3943613 sacX 937333 sacX Bacillus subtilis subsp. subtilis str. 168 negative regulator of SacY activity NP_391720.1 3942234 D 224308 CDS NP_391721.1 16080893 937335 3943667..3944509 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11580842, 12079345, 15528654, 9305644, 9457872; Product type r: regulator; levansucrase and sucrase synthesis operon antiterminator 3944509 sacY 937335 sacY Bacillus subtilis subsp. subtilis str. 168 levansucrase and sucrase synthesis operon antiterminator NP_391721.1 3943667 D 224308 CDS NP_391722.1 16080894 937339 complement(3944560..3945420) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11377871; Product type pe : enzyme; general stress protein A 3945420 gspA 937339 gspA Bacillus subtilis subsp. subtilis str. 168 general stress protein A NP_391722.1 3944560 R 224308 CDS NP_391723.1 16080895 937341 complement(3945530..3946243) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3946243 ywaF 937341 ywaF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391723.1 3945530 R 224308 CDS NP_391724.1 16080896 937344 3946394..3946909 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YwaE 3946909 ywaE 937344 ywaE Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YwaE NP_391724.1 3946394 D 224308 CDS NP_391725.1 16080897 937345 3947158..3948399 1 NC_000964.3 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosine--tRNA ligase 2 3948399 tyrZ 937345 tyrZ Bacillus subtilis subsp. subtilis str. 168 tyrosine--tRNA ligase 2 NP_391725.1 3947158 D 224308 CDS NP_391726.1 16080898 937350 3948555..3949922 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15668014; Product type e: enzyme; aminopeptidase YwaD 3949922 ywaD 937350 ywaD Bacillus subtilis subsp. subtilis str. 168 aminopeptidase YwaD NP_391726.1 3948555 D 224308 CDS NP_391727.1 16080899 937355 complement(3949952..3950584) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17114254, 18067544; Product type e: enzyme; GTP pyrophosphokinase YwaC 3950584 ywaC 937355 ywaC Bacillus subtilis subsp. subtilis str. 168 GTP pyrophosphokinase YwaC NP_391727.1 3949952 R 224308 CDS NP_391728.1 16080900 937356 complement(3950726..3951661) 1 NC_000964.3 catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate; 1,4-dihydroxy-2-naphthoate octaprenyltransferase 3951661 menA 937356 menA Bacillus subtilis subsp. subtilis str. 168 1,4-dihydroxy-2-naphthoate octaprenyltransferase NP_391728.1 3950726 R 224308 CDS YP_003097795.1 255767815 8303014 3952108..3952257 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; membrane protein 3952257 ywzH 8303014 ywzH Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097795.1 3952108 D 224308 CDS NP_391729.1 16080901 937358 3952275..3953786 1 NC_000964.3 transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 3953786 dltA 937358 dltA Bacillus subtilis subsp. subtilis str. 168 D-alanine--poly(phosphoribitol) ligase subunit 1 NP_391729.1 3952275 D 224308 CDS NP_391730.1 16080902 937360 3953783..3954970 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 15849754, 16850406, 17263852; Product type e : enzyme; protein DltB 3954970 dltB 937360 dltB Bacillus subtilis subsp. subtilis str. 168 protein DltB NP_391730.1 3953783 D 224308 CDS NP_391731.1 16080903 937361 3954987..3955223 1 NC_000964.3 D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 3955223 dltC 937361 dltC Bacillus subtilis subsp. subtilis str. 168 D-alanine--poly(phosphoribitol) ligase subunit 2 NP_391731.1 3954987 D 224308 CDS NP_391732.1 16080904 937362 3955223..3956401 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11222605, 12028417, 14665680, 17263852; Product type pe: enzyme; poly D-alanine transfer protein DltD 3956401 dltD 937362 dltD Bacillus subtilis subsp. subtilis str. 168 poly D-alanine transfer protein DltD NP_391732.1 3955223 D 224308 CDS NP_391733.2 255767816 937369 3956492..3957250 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14665680, 7797557; Product type pe: enzyme; oxidoreductase 3957250 dltE 937369 dltE Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391733.2 3956492 D 224308 CDS NP_391734.2 255767817 937372 3957391..3958482 1 NC_000964.3 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain-amino acid aminotransferase 2 3958482 ywaA 937372 ywaA Bacillus subtilis subsp. subtilis str. 168 branched-chain-amino acid aminotransferase 2 NP_391734.2 3957391 D 224308 CDS NP_391735.1 16080907 937373 complement(3958516..3959844) 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 8990303; Product type e: enzyme; 6-phospho-beta-glucosidase 3959844 licH 937373 licH Bacillus subtilis subsp. subtilis str. 168 6-phospho-beta-glucosidase NP_391735.1 3958516 R 224308 CDS NP_391736.1 16080908 937374 complement(3959841..3960173) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303; Product type t: transporter; PTS system lichenan transporter subunit IIA 3960173 licA 937374 licA Bacillus subtilis subsp. subtilis str. 168 PTS system lichenan transporter subunit IIA NP_391736.1 3959841 R 224308 CDS NP_391737.1 16080909 937375 complement(3960192..3961550) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 15849754, 16850406; Product type t: transporter; PTS system lichenan transporter subunit IIC 3961550 licC 937375 licC Bacillus subtilis subsp. subtilis str. 168 PTS system lichenan transporter subunit IIC NP_391737.1 3960192 R 224308 CDS NP_391738.1 16080910 937379 complement(3961566..3961874) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772; Product type t: transporter; PTS system lichenan transporter subunit IIB 3961874 licB 937379 licB Bacillus subtilis subsp. subtilis str. 168 PTS system lichenan transporter subunit IIB NP_391738.1 3961566 R 224308 CDS NP_391739.1 16080911 937383 complement(3962003..3963928) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10438772, 8990303, 9353933; Product type r: regulator; licABCH operon regulator 3963928 licR 937383 licR Bacillus subtilis subsp. subtilis str. 168 licABCH operon regulator NP_391739.1 3962003 R 224308 CDS NP_391740.1 16080912 937390 complement(3964091..3964249) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3964249 yxzF 937390 yxzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391740.1 3964091 R 224308 CDS NP_391741.1 16080913 937391 complement(3964278..3964868) 1 NC_000964.3 responsible for recognizing base lesions in the genome and initiating base excision DNA repair; 3-methyladenine DNA glycosylase 3964868 yxlJ 937391 yxlJ Bacillus subtilis subsp. subtilis str. 168 3-methyladenine DNA glycosylase NP_391741.1 3964278 R 224308 CDS NP_391742.1 16080914 937399 3964997..3966640 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10503549, 9393707, 9555886; Product type e: enzyme; catalase X 3966640 katX 937399 katX Bacillus subtilis subsp. subtilis str. 168 catalase X NP_391742.1 3964997 D 224308 CDS NP_391743.1 16080915 937392 3966745..3967947 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; MFS transporter 3967947 yxlH 937392 yxlH Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391743.1 3966745 D 224308 CDS NP_391744.2 255767818 937394 complement(3967944..3968720) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14769884, 15849754, 16850406; Product type pt: transporter; transmembrane protein YxlG 3968720 yxlG 937394 yxlG Bacillus subtilis subsp. subtilis str. 168 transmembrane protein YxlG NP_391744.2 3967944 R 224308 CDS NP_391745.1 16080917 938137 complement(3968717..3969604) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pt: transporter; ABC transporter ATP-binding protein 3969604 yxlF 938137 yxlF Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391745.1 3968717 R 224308 CDS NP_391746.1 16080918 937395 complement(3969611..3969799) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator; negative regulatory protein YxlE 3969799 yxlE 937395 yxlE Bacillus subtilis subsp. subtilis str. 168 negative regulatory protein YxlE NP_391746.1 3969611 R 224308 CDS NP_391747.1 16080919 937398 complement(3969796..3970002) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12897008, 14769884, 14993308; Product type pr: regulator; negative regulatory protein YxlD 3970002 yxlD 937398 yxlD Bacillus subtilis subsp. subtilis str. 168 negative regulatory protein YxlD NP_391747.1 3969796 R 224308 CDS NP_391748.1 16080920 938082 complement(3969999..3970319) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12897008, 14769884, 14993308; Product type r: regulator; hypothetical protein 3970319 yxlC 938082 yxlC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391748.1 3969999 R 224308 CDS NP_391749.1 16080921 937400 complement(3970312..3970848) 1 NC_000964.3 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; RNA polymerase sigma factor SigY 3970848 sigY 937400 sigY Bacillus subtilis subsp. subtilis str. 168 RNA polymerase sigma factor SigY NP_391749.1 3970312 R 224308 CDS NP_391750.1 16080922 937405 3971060..3972433 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 2191181; Product type pt: transporter; purine-cytosine permease YxlA 3972433 yxlA 937405 yxlA Bacillus subtilis subsp. subtilis str. 168 purine-cytosine permease YxlA NP_391750.1 3971060 D 224308 CDS NP_391751.1 16080923 937408 complement(3972448..3973278) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12457846; Product type pe : enzyme; adp-dependent (S)-NAD(P)H-hydrate dehydratase 3973278 yxkO 937408 yxkO Bacillus subtilis subsp. subtilis str. 168 adp-dependent (S)-NAD(P)H-hydrate dehydratase NP_391751.1 3972448 R 224308 CDS NP_391752.1 16080924 936330 complement(3973364..3975091) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter; ATP-binding/permease protein CydD 3975091 cydD 936330 cydD Bacillus subtilis subsp. subtilis str. 168 ATP-binding/permease protein CydD NP_391752.1 3973364 R 224308 CDS NP_391753.1 16080925 936498 complement(3975088..3976791) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15231791, 16040611, 9852001; Product type t : transporter; ATP-binding/permease protein CydC 3976791 cydC 936498 cydC Bacillus subtilis subsp. subtilis str. 168 ATP-binding/permease protein CydC NP_391753.1 3975088 R 224308 CDS NP_391754.1 16080926 937412 complement(3976791..3977807) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme; cytochrome d ubiquinol oxidase subunit 2 3977807 cydB 937412 cydB Bacillus subtilis subsp. subtilis str. 168 cytochrome d ubiquinol oxidase subunit 2 NP_391754.1 3976791 R 224308 CDS NP_391755.1 16080927 937406 complement(3977791..3979197) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15231791, 15849754, 16850406, 9852001; Product type e: enzyme; cytochrome d ubiquinol oxidase subunit 1 3979197 cydA 937406 cydA Bacillus subtilis subsp. subtilis str. 168 cytochrome d ubiquinol oxidase subunit 1 NP_391755.1 3977791 R 224308 CDS NP_391756.1 16080928 937407 3979753..3981105 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566984, 15849754, 16850406; Product type t: transporter; citrate/malate transporter 3981105 cimH 937407 cimH Bacillus subtilis subsp. subtilis str. 168 citrate/malate transporter NP_391756.1 3979753 D 224308 CDS NP_391757.1 16080929 937415 3981227..3982915 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pe : enzyme; membrane metalloprotease YxkI 3982915 yxkI 937415 yxkI Bacillus subtilis subsp. subtilis str. 168 membrane metalloprotease YxkI NP_391757.1 3981227 D 224308 CDS NP_391758.1 16080930 937409 3982973..3983173 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16845009; Product type pf : factor; hypothetical protein 3983173 yxzE 937409 yxzE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391758.1 3982973 D 224308 CDS NP_391759.1 16080931 937411 complement(3983187..3984026) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; polysaccharide deacetylase 3984026 yxkH 937411 yxkH Bacillus subtilis subsp. subtilis str. 168 polysaccharide deacetylase NP_391759.1 3983187 R 224308 CDS NP_391760.1 16080932 937422 complement(3984133..3985230) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16707683; Product type t: transporter; maltodextrin import ATP-binding protein MsmX 3985230 msmX 937422 msmX Bacillus subtilis subsp. subtilis str. 168 maltodextrin import ATP-binding protein MsmX NP_391760.1 3984133 R 224308 CDS NP_391761.1 16080933 937413 complement(3985351..3986244) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pr : regulator; hypothetical protein 3986244 yxkF 937413 yxkF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391761.1 3985351 R 224308 CDS NP_391762.1 16080934 937414 3986428..3987885 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10482513; Product type pe : enzyme; aldehyde dehydrogenase AldY 3987885 aldY 937414 aldY Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase AldY NP_391762.1 3986428 D 224308 CDS NP_391763.1 16080935 937425 complement(3987927..3988763) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10735877, 10931887, 15096624, 15849754, 16850406; Product type t : transporter; hypothetical protein 3988763 yxkD 937425 yxkD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391763.1 3987927 R 224308 CDS NP_391764.1 16080936 937416 3989232..3989873 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12823818, 15033535; hypothetical protein 3989873 yxkC 937416 yxkC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391764.1 3989232 D 224308 CDS NP_391765.1 16080937 937420 complement(3989948..3990967) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14597172, 9555917; Product type e: enzyme; UDP-glucose 4-epimerase 3990967 galE 937420 galE Bacillus subtilis subsp. subtilis str. 168 UDP-glucose 4-epimerase NP_391765.1 3989948 R 224308 CDS NP_391766.1 16080938 937438 complement(3991082..3991588) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 3991588 yxkA 937438 yxkA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391766.1 3991082 R 224308 CDS NP_391767.1 16080939 937423 3991718..3992593 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12169591; Product type pr : regulator; HTH-type transcriptional regulator YxjO 3992593 yxjO 937423 yxjO Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YxjO NP_391767.1 3991718 D 224308 CDS NP_391768.1 16080940 937424 3992671..3993144 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 3993144 yxjN 937424 yxjN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391768.1 3992671 D 224308 CDS NP_391769.1 16080941 937441 3993162..3994382 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type rc: receptor; sensor histidine kinase 3994382 yxjM 937441 yxjM Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391769.1 3993162 D 224308 CDS NP_391770.1 16080942 937427 3994369..3995025 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295; Product type r: regulator; transcriptional regulator 3995025 yxjL 937427 yxjL Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391770.1 3994369 D 224308 CDS NP_391771.1 16080943 937428 3995075..3996307 1 NC_000964.3 catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T 3996307 pepT 937428 pepT Bacillus subtilis subsp. subtilis str. 168 peptidase T NP_391771.1 3995075 D 224308 CDS NP_391772.1 16080944 937454 3996829..3997092 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 3997092 yxjJ 937454 yxjJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391772.1 3996829 D 224308 CDS NP_391773.1 16080945 937439 3997221..3997709 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 3997709 yxjI 937439 yxjI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391773.1 3997221 D 224308 CDS NP_391774.2 255767819 937440 3997964..3999097 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320, 17098890; Product type pe: enzyme; hypothetical protein 3999097 yxjH 937440 yxjH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391774.2 3997964 D 224308 CDS NP_391775.3 255767820 937457 3999350..4000486 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12456320; Product type pe : enzyme; hypothetical protein 4000486 yxjG 937457 yxjG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391775.3 3999350 D 224308 CDS NP_391776.2 255767821 937450 complement(4000539..4001312) 1 NC_000964.3 catalyzes the formation of acetoacetate from 3-hydroxybutyrate; oxidoreductase 4001312 yxjF 937450 yxjF Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391776.2 4000539 R 224308 CDS NP_391777.1 16080949 937453 complement(4001329..4001979) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme; succinyl-CoA:3-ketoacid coenzyme A transferase subunit B 4001979 scoB 937453 scoB Bacillus subtilis subsp. subtilis str. 168 succinyl-CoA:3-ketoacid coenzyme A transferase subunit B NP_391777.1 4001329 R 224308 CDS NP_391778.1 16080950 937468 complement(4001976..4002692) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17363272; Product type e: enzyme; succinyl-CoA:3-ketoacid coenzyme A transferase subunit A 4002692 scoA 937468 scoA Bacillus subtilis subsp. subtilis str. 168 succinyl-CoA:3-ketoacid coenzyme A transferase subunit A NP_391778.1 4001976 R 224308 CDS NP_391779.3 255767822 937455 complement(4002716..4004134) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4004134 yxjC 937455 yxjC Bacillus subtilis subsp. subtilis str. 168 transporter NP_391779.3 4002716 R 224308 CDS NP_391780.1 16080952 937456 complement(4004288..4005136) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; 23S rRNA (guanine-N(1)-)-methyltransferase YxjB 4005136 yxjB 937456 yxjB Bacillus subtilis subsp. subtilis str. 168 23S rRNA (guanine-N(1)-)-methyltransferase YxjB NP_391780.1 4004288 R 224308 CDS NP_391781.2 255767823 937472 4005752..4006945 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 12787499, 15849754, 16850406; Product type t: transporter; purine nucleoside transport protein NupG 4006945 yxjA 937472 yxjA Bacillus subtilis subsp. subtilis str. 168 purine nucleoside transport protein NupG NP_391781.2 4005752 D 224308 CDS NP_391783.2 255767824 937467 complement(4007803..4008093) 1 NC_000964.3 Evidence 7: Gene remnant; hypothetical protein 4008093 yxiS 937467 yxiS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391783.2 4007803 R 224308 CDS NP_391784.2 255767825 937481 complement(4008143..4010203) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16151211, 7559348, 8931328; Product type e: enzyme; catalase-2 4010203 katE 937481 katE Bacillus subtilis subsp. subtilis str. 168 catalase-2 NP_391784.2 4008143 R 224308 CDS NP_391785.2 255767826 937469 4010404..4011684 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11053381, 15849754, 16850406, 8892821; Product type t: transporter; citrate transporter 4011684 citH 937469 citH Bacillus subtilis subsp. subtilis str. 168 citrate transporter NP_391785.2 4010404 D 224308 CDS NP_391786.1 16080958 937470 complement(4011842..4012570) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1369198, 3106158, 7704256; Product type e: enzyme; beta-glucanase 4012570 bglS 937470 bglS Bacillus subtilis subsp. subtilis str. 168 beta-glucanase NP_391786.1 4011842 R 224308 CDS NP_391787.2 255767827 937503 complement(4012866..4013699) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11447120, 11580842, 11733988, 12169607, 15699035; Product type r: regulator; transcription antiterminator LicT 4013699 licT 937503 licT Bacillus subtilis subsp. subtilis str. 168 transcription antiterminator LicT NP_391787.2 4012866 R 224308 CDS NP_391788.1 16080960 937473 complement(4013795..4014475) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein; hypothetical protein 4014475 yxiP 937473 yxiP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391788.1 4013795 R 224308 CDS NP_391789.1 16080961 937480 4014682..4015968 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12583894, 15849754, 16850406; Product type pt: transporter; MFS transporter 4015968 yxiO 937480 yxiO Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391789.1 4014682 D 224308 CDS NP_391790.2 255767828 937492 complement(4015987..4017426) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10481020, 16118224, 16611943, 17142894, 17229151, 17951299; Product type e : enzyme; ATP-dependent RNA helicase DbpA 4017426 deaD 937492 deaD Bacillus subtilis subsp. subtilis str. 168 ATP-dependent RNA helicase DbpA NP_391790.2 4015987 R 224308 CDS NP_391791.2 255767829 937485 complement(4017508..4018656) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760; Product type pe : enzyme; esterase YxiM 4018656 yxiM 937485 yxiM Bacillus subtilis subsp. subtilis str. 168 esterase YxiM NP_391791.2 4017508 R 224308 CDS YP_003097796.1 255767830 8303069 complement(4019005..4019136) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4019136 yxzJ 8303069 yxzJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097796.1 4019005 R 224308 CDS NP_391793.1 16080965 937483 complement(4019148..4019609) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 4019609 yxiK 937483 yxiK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391793.1 4019148 R 224308 CDS NP_391794.1 16080966 937504 complement(4019625..4019921) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4019921 yxiJ 937504 yxiJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391794.1 4019625 R 224308 CDS NP_391795.1 16080967 937495 complement(4019949..4020437) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4020437 yxiI 937495 yxiI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391795.1 4019949 R 224308 CDS NP_391796.1 16080968 937507 complement(4020455..4020907) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 4020907 yxzG 937507 yxzG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391796.1 4020455 R 224308 CDS NP_391797.1 16080969 937476 complement(4020977..4021306) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4021306 yxiH 937476 yxiH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391797.1 4020977 R 224308 CDS NP_391798.1 16080970 937774 complement(4021429..4021845) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4021845 yxiG 937774 yxiG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391798.1 4021429 R 224308 CDS NP_391799.1 16080971 937967 complement(4021896..4022264) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: factor; hypothetical protein 4022264 yxzC 937967 yxzC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391799.1 4021896 R 224308 CDS NP_391800.1 16080972 937519 complement(4022258..4022728) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4022728 yxiF 937519 yxiF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391800.1 4022258 R 224308 CDS NP_391801.1 16080973 937508 complement(4023054..4023482) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 1529529, 16306698; hypothetical protein 4023482 yxxG 937508 yxxG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391801.1 4023054 R 224308 CDS NP_391802.2 255767831 937525 complement(4023544..4030548) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16306698, 16849803, 9537385; Product type f: factor; wall-associated protein 4030548 wapA 937525 wapA Bacillus subtilis subsp. subtilis str. 168 wall-associated protein NP_391802.2 4023544 R 224308 CDS NP_391803.1 16080975 937510 complement(4030710..4031645) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4031645 yxxF 937510 yxxF Bacillus subtilis subsp. subtilis str. 168 transporter NP_391803.1 4030710 R 224308 CDS NP_391804.1 16080976 937971 complement(4031797..4032243) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10913081, 12644671, 17210127; Product type f: factor; universal stress protein YxiE 4032243 yxiE 937971 yxiE Bacillus subtilis subsp. subtilis str. 168 universal stress protein YxiE NP_391804.1 4031797 R 224308 CDS NP_391805.2 50812306 937512 complement(4032346..4033755) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglH 4033755 bglH 937512 bglH Bacillus subtilis subsp. subtilis str. 168 aryl-phospho-beta-d-glucosidase BglH NP_391805.2 4032346 R 224308 CDS NP_391806.2 255767832 937518 complement(4033778..4035607) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 16850406, 17074746, 8626332; Product type t: transporter; PTS system beta-glucoside-specific EIIBCA component 4035607 bglP 937518 bglP Bacillus subtilis subsp. subtilis str. 168 PTS system beta-glucoside-specific EIIBCA component NP_391806.2 4033778 R 224308 CDS NP_391807.1 16080979 937520 complement(4035990..4036298) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4036298 yxxE 937520 yxxE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391807.1 4035990 R 224308 CDS NP_391808.1 16080980 937530 complement(4036344..4036787) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4036787 yxxD 937530 yxxD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391808.1 4036344 R 224308 CDS NP_391809.2 255767833 937523 complement(4036784..4038493) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 4038493 yxiD 937523 yxiD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391809.2 4036784 R 224308 CDS NP_391810.1 16080982 937521 complement(4038513..4038782) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4038782 yxiC 937521 yxiC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391810.1 4038513 R 224308 CDS NP_391811.1 16080983 937532 complement(4038794..4039159) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4039159 yxiB 937532 yxiB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391811.1 4038794 R 224308 CDS NP_391812.2 255767834 937533 complement(4039466..4040875) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14973026, 18408032; Product type e: enzyme; arabinan endo-1,5-alpha-L-arabinosidase 4040875 abnB 937533 abnB Bacillus subtilis subsp. subtilis str. 168 arabinan endo-1,5-alpha-L-arabinosidase NP_391812.2 4039466 R 224308 CDS YP_003097797.1 255767835 8302942 complement(4041009..4041173) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4041173 yxzL 8302942 yxzL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097797.1 4041009 R 224308 CDS NP_391813.1 16080985 937529 4041483..4041938 1 NC_000964.3 regulates expression of hut operon by antitermination mechanism; forms a homohexamer; binds both magnesium and L-histidine and then binds RNA sequences within the terminator region and destabilizes the terminator structure; anti-terminator HutP 4041938 hutP 937529 hutP Bacillus subtilis subsp. subtilis str. 168 anti-terminator HutP NP_391813.1 4041483 D 224308 CDS NP_391814.1 16080986 937541 4042051..4043577 1 NC_000964.3 catalyzes the degradation of histidine to urocanate and ammmonia; histidine ammonia-lyase 4043577 hutH 937541 hutH Bacillus subtilis subsp. subtilis str. 168 histidine ammonia-lyase NP_391814.1 4042051 D 224308 CDS NP_391815.1 16080987 937542 4043574..4045232 1 NC_000964.3 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism; urocanate hydratase 4045232 hutU 937542 hutU Bacillus subtilis subsp. subtilis str. 168 urocanate hydratase NP_391815.1 4043574 D 224308 CDS NP_391816.1 16080988 937531 4045245..4046510 1 NC_000964.3 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway; imidazolonepropionase 4046510 hutI 937531 hutI Bacillus subtilis subsp. subtilis str. 168 imidazolonepropionase NP_391816.1 4045245 D 224308 CDS NP_391817.1 16080989 937546 4046503..4047462 1 NC_000964.3 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate; formimidoylglutamase 4047462 hutG 937546 hutG Bacillus subtilis subsp. subtilis str. 168 formimidoylglutamase NP_391817.1 4046503 D 224308 CDS NP_391818.2 255767836 938565 4047538..4048965 1 NC_000964.3 Evidence 2b: Function of strongly homologous gene; PubMedId: 15849754, 16850406, 7704263; Product type t: transporter; histidine permease 4048965 hutM 938565 hutM Bacillus subtilis subsp. subtilis str. 168 histidine permease NP_391818.2 4047538 D 224308 CDS NP_391819.2 50812307 937540 complement(4049009..4050310) 1 NC_000964.3 Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 4050310 pdp 937540 pdp Bacillus subtilis subsp. subtilis str. 168 pyrimidine-nucleoside phosphorylase NP_391819.2 4049009 R 224308 CDS NP_391820.2 255767837 937534 complement(4050340..4051521) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11065368, 15849754, 16850406, 8550462; Product type t: transporter; pyrimidine nucleoside transport protein 4051521 nupC 937534 nupC Bacillus subtilis subsp. subtilis str. 168 pyrimidine nucleoside transport protein NP_391820.2 4050340 R 224308 CDS NP_391821.2 255767838 938608 complement(4051602..4052273) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 11065368, 8550462; Product type e: enzyme; deoxyribose-phosphate aldolase 4052273 deoC 938608 deoC Bacillus subtilis subsp. subtilis str. 168 deoxyribose-phosphate aldolase NP_391821.2 4051602 R 224308 CDS NP_391822.1 16080994 937543 complement(4052379..4053320) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10074062, 10714997, 8550462; Product type r: regulator; deoxyribonucleoside regulator 4053320 deoR 937543 deoR Bacillus subtilis subsp. subtilis str. 168 deoxyribonucleoside regulator NP_391822.1 4052379 R 224308 CDS NP_391823.2 255767839 937547 complement(4053454..4054281) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4054281 yxxB 937547 yxxB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391823.2 4053454 R 224308 CDS NP_391824.1 16080996 937551 complement(4054354..4055466) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10746760, 15849754, 16850406; Product type pt: transporter; hypothetical protein 4055466 yxeR 937551 yxeR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391824.1 4054354 R 224308 CDS NP_391825.2 255767840 938528 complement(4055536..4056873) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; hypothetical protein 4056873 yxeQ 938528 yxeQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391825.2 4055536 R 224308 CDS NP_391826.2 255767841 937572 complement(4056870..4058012) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; hydrolase YxeP 4058012 yxeP 937572 yxeP Bacillus subtilis subsp. subtilis str. 168 hydrolase YxeP NP_391826.2 4056870 R 224308 CDS NP_391827.1 16080999 937555 complement(4058029..4058778) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pt: transporter; amino acid import ATP-binding protein YxeO 4058778 yxeO 937555 yxeO Bacillus subtilis subsp. subtilis str. 168 amino acid import ATP-binding protein YxeO NP_391827.1 4058029 R 224308 CDS NP_391828.1 16081000 937554 complement(4058791..4059465) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 15849754, 16513748, 16850406, 16885442; Product type pt: transporter; amino acid permease protein YxeN 4059465 yxeN 937554 yxeN Bacillus subtilis subsp. subtilis str. 168 amino acid permease protein YxeN NP_391828.1 4058791 R 224308 CDS NP_391829.1 16081001 937568 complement(4059488..4060282) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type lp: lipoprotein; amino acid-binding protein YxeM 4060282 yxeM 937568 yxeM Bacillus subtilis subsp. subtilis str. 168 amino acid-binding protein YxeM NP_391829.1 4059488 R 224308 CDS NP_391830.2 255767842 937563 complement(4060307..4060804) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; N-acetyltransferase YxeL 4060804 yxeL 937563 yxeL Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YxeL NP_391830.2 4060307 R 224308 CDS NP_391831.1 16081003 937570 complement(4060818..4062143) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12193636, 16513748, 16885442; Product type pe: enzyme; monooxygenase YxeK 4062143 yxeK 937570 yxeK Bacillus subtilis subsp. subtilis str. 168 monooxygenase YxeK NP_391831.1 4060818 R 224308 CDS NP_391832.2 255767843 937574 complement(4062329..4062556) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4062556 yxeJ 937574 yxeJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391832.2 4062329 R 224308 CDS NP_391833.2 255767844 937573 complement(4062543..4063529) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15937167; Product type pe : enzyme; hypothetical protein 4063529 yxeI 937573 yxeI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391833.2 4062543 R 224308 CDS NP_391834.1 16081006 937571 complement(4063684..4064496) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4064496 yxeH 937571 yxeH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391834.1 4063684 R 224308 CDS NP_391835.1 16081007 937586 complement(4064536..4065093) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4065093 yxeG 937586 yxeG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391835.1 4064536 R 224308 CDS NP_391836.1 16081008 937562 complement(4065074..4065508) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; PubMedId: 11160890; hypothetical protein 4065508 yxeF 937562 yxeF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391836.1 4065074 R 224308 CDS NP_391837.1 16081009 936477 4065597..4065962 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10714992, 17905812; Product type s: structure; hypothetical protein 4065962 yxeE 936477 yxeE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391837.1 4065597 D 224308 CDS NP_391838.2 255767845 937597 4066210..4066563 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4066563 yxeD 937597 yxeD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391838.2 4066210 D 224308 CDS NP_391839.2 255767846 937578 complement(4066607..4067005) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4067005 yxeC 937578 yxeC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391839.2 4066607 R 224308 CDS NP_391840.2 255767847 937581 4067183..4068148 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12354229, 16672620, 8388528; Product type t: transporter; iron(3+)-hydroxamate-binding protein YxeB 4068148 yxeB 937581 yxeB Bacillus subtilis subsp. subtilis str. 168 iron(3+)-hydroxamate-binding protein YxeB NP_391840.2 4067183 D 224308 CDS NP_391841.1 16081013 937612 complement(4068189..4068536) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4068536 yxeA 937612 yxeA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391841.1 4068189 R 224308 CDS NP_391842.2 255767848 937589 complement(4068550..4070418) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15849754, 15870467, 16850406; Product type t: transporter; ABC transporter permease 4070418 yxdM 937589 yxdM Bacillus subtilis subsp. subtilis str. 168 ABC transporter permease NP_391842.2 4068550 R 224308 CDS NP_391843.2 255767849 937596 complement(4070393..4071166) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15289557, 15870467; Product type t: transporter; ABC transporter ATP-binding protein 4071166 yxdL 937596 yxdL Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391843.2 4070393 R 224308 CDS NP_391844.1 16081016 937487 complement(4071310..4072287) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type e: enzyme; sensor histidine kinase 4072287 yxdK 937487 yxdK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391844.1 4071310 R 224308 CDS NP_391845.1 16081017 937599 complement(4072284..4072973) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11717295, 15289557, 15870467; Product type r: regulator; transcriptional regulator 4072973 yxdJ 937599 yxdJ Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391845.1 4072284 R 224308 CDS NP_391846.1 16081018 937601 complement(4073081..4073953) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10658656, 11325924, 18310071, 9226270; Product type e: enzyme; 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase 4073953 iolJ 937601 iolJ Bacillus subtilis subsp. subtilis str. 168 6-phospho-5-dehydro-2-deoxy-D-gluconate aldolase NP_391846.1 4073081 R 224308 CDS NP_391847.1 16081019 937582 complement(4073974..4074810) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 17619021, 9887260; Product type pe: enzyme; inosose isomerase 4074810 iolI 937582 iolI Bacillus subtilis subsp. subtilis str. 168 inosose isomerase NP_391847.1 4073974 R 224308 CDS NP_391848.1 16081020 937613 complement(4074896..4075765) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11566986, 12112707, 9887260; Product type pe: enzyme; myo-inositol catabolism protein IolH 4075765 iolH 937613 iolH Bacillus subtilis subsp. subtilis str. 168 myo-inositol catabolism protein IolH NP_391848.1 4074896 R 224308 CDS NP_391849.2 255767850 937615 complement(4075785..4076819) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11274120, 15678175, 9226270; Product type e: enzyme; inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase 4076819 iolG 937615 iolG Bacillus subtilis subsp. subtilis str. 168 inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase NP_391849.2 4075785 R 224308 CDS NP_391850.2 255767851 937616 complement(4076842..4078158) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807058, 15849754, 16850406; Product type t: transporter; minor myo-inositol transporter IolF 4078158 iolF 937616 iolF Bacillus subtilis subsp. subtilis str. 168 minor myo-inositol transporter IolF NP_391850.2 4076842 R 224308 CDS NP_391851.1 16081023 936212 complement(4078173..4079066) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14993306, 9226270; Product type e: enzyme; inosose dehydratase 4079066 iolE 936212 iolE Bacillus subtilis subsp. subtilis str. 168 inosose dehydratase NP_391851.1 4078173 R 224308 CDS NP_391852.2 255767852 937590 complement(4079083..4080996) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase 4080996 iolD 937590 iolD Bacillus subtilis subsp. subtilis str. 168 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase NP_391852.2 4079083 R 224308 CDS NP_391853.1 16081025 937622 complement(4081029..4082006) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 5-dehydro-2-deoxygluconokinase 4082006 iolC 937622 iolC Bacillus subtilis subsp. subtilis str. 168 5-dehydro-2-deoxygluconokinase NP_391853.1 4081029 R 224308 CDS NP_391854.2 255767853 937580 complement(4082030..4082845) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 12112707, 18310071, 9887260; Product type e: enzyme; 5-deoxy-glucuronate isomerase 4082845 iolB 937580 iolB Bacillus subtilis subsp. subtilis str. 168 5-deoxy-glucuronate isomerase NP_391854.2 4082030 R 224308 CDS NP_391855.1 16081027 937575 complement(4082920..4084383) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10658656, 11566986, 16332250; Product type e: enzyme; methylmalonate semialdehyde dehydrogenase 4084383 mmsA 937575 mmsA Bacillus subtilis subsp. subtilis str. 168 methylmalonate semialdehyde dehydrogenase NP_391855.1 4082920 R 224308 CDS NP_391856.1 16081028 937635 4084799..4085554 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11566986, 11807058, 9887260; Product type r: regulator; HTH-type transcriptional regulator IolR 4085554 iolR 937635 iolR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator IolR NP_391856.1 4084799 D 224308 CDS NP_391857.1 16081029 937636 4085608..4086540 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15019785, 9226270; Product type e: enzyme; aldo/keto reductase family protein IolS 4086540 iolS 937636 iolS Bacillus subtilis subsp. subtilis str. 168 aldo/keto reductase family protein IolS NP_391857.1 4085608 D 224308 CDS NP_391858.1 16081030 937621 4086802..4087452 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4087452 yxcE 937621 yxcE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391858.1 4086802 D 224308 CDS NP_391859.1 16081031 937638 4087456..4087764 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4087764 yxcD 937638 yxcD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391859.1 4087456 D 224308 CDS NP_391860.1 16081032 937639 4088002..4089387 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10376822, 15849754, 16850406; Product type pt: transporter; metabolite transport protein CsbC 4089387 csbC 937639 csbC Bacillus subtilis subsp. subtilis str. 168 metabolite transport protein CsbC NP_391860.1 4088002 D 224308 CDS NP_391861.1 16081033 937631 complement(4089429..4091309) 1 NC_000964.3 molecular chaperone; chaperone protein HtpG 4091309 htpG 937631 htpG Bacillus subtilis subsp. subtilis str. 168 chaperone protein HtpG NP_391861.1 4089429 R 224308 CDS NP_391862.1 16081034 937641 complement(4091477..4091728) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4091728 yxcA 937641 yxcA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391862.1 4091477 R 224308 CDS NP_391863.2 50812308 937642 4091845..4092666 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 4092666 yxbG 937642 yxbG Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391863.2 4091845 D 224308 CDS NP_391864.1 16081036 937637 complement(4092695..4093837) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 11160890; Product type pr : regulator; HTH-type transcriptional regulator YxbF 4093837 yxbF 937637 yxbF Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YxbF NP_391864.1 4092695 R 224308 CDS NP_391865.2 255767854 937653 4093980..4095317 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; aldehyde dehydrogenase AldX 4095317 aldX 937653 aldX Bacillus subtilis subsp. subtilis str. 168 aldehyde dehydrogenase AldX NP_391865.2 4093980 D 224308 CDS NP_391866.2 255767855 937655 complement(4095356..4095835) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4095835 yxbD 937655 yxbD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391866.2 4095356 R 224308 CDS NP_391867.1 16081039 937640 complement(4095915..4096907) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4096907 yxbC 937640 yxbC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391867.1 4095915 R 224308 CDS NP_391868.1 16081040 937673 4097416..4098150 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15941984; Product type pe : enzyme; hypothetical protein 4098150 yxbB 937673 yxbB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391868.1 4097416 D 224308 CDS NP_391869.1 16081041 937675 4098150..4098419 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 17083466; Product type e: enzyme; hypothetical protein 4098419 aslA 937675 aslA Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391869.1 4098150 D 224308 CDS NP_391870.1 16081042 937643 4098423..4098905 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4098905 yxnB 937643 yxnB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391870.1 4098423 D 224308 CDS NP_391871.2 255767856 937677 4098926..4101169 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10498721, 17083466; Product type e: enzyme; asparagine synthetase 2 4101169 asnH 937677 asnH Bacillus subtilis subsp. subtilis str. 168 asparagine synthetase 2 NP_391871.2 4098926 D 224308 CDS NP_391872.2 255767857 937678 4101166..4102365 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15101989, 15849754, 16850406; Product type pt: transporter; MFS transporter 4102365 yxaM 937678 yxaM Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391872.2 4101166 D 224308 CDS NP_391873.2 50812309 937661 complement(4102429..4103661) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12073041, 15743949; Product type e: enzyme; hypothetical protein 4103661 yxaL 937661 yxaL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391873.2 4102429 R 224308 CDS NP_391875.2 255767858 937687 complement(4103762..4104187) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4104187 yxaJ 937687 yxaJ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391875.2 4103762 R 224308 CDS NP_391876.1 16081048 937676 4104444..4104899 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4104899 yxaI 937676 yxaI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391876.1 4104444 D 224308 CDS NP_391877.2 255767859 937697 complement(4104929..4106137) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15317768, 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4106137 yxaH 937697 yxaH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391877.2 4104929 R 224308 CDS NP_391878.2 255767860 937689 complement(4106245..4107258) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14697267, 15317768, 15628860, 17483215; Product type e: enzyme; quercetin 2,3-dioxygenase 4107258 qodI 937689 qodI Bacillus subtilis subsp. subtilis str. 168 quercetin 2,3-dioxygenase NP_391878.2 4106245 R 224308 CDS NP_391879.2 255767861 937690 complement(4107352..4107927) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 17483215; Product type r: regulator; HTH-type transcriptional regulator YxaF 4107927 yxaF 937690 yxaF Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YxaF NP_391879.2 4107352 R 224308 CDS NP_391880.2 50812310 937698 4108058..4109128 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; oxidoreductase 4109128 yxnA 937698 yxnA Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391880.2 4108058 D 224308 CDS NP_391881.1 16081053 937699 complement(4109185..4109616) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YxaD 4109616 yxaD 937699 yxaD Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YxaD NP_391881.1 4109185 R 224308 CDS YP_003097798.1 255767862 8303163 4109843..4110247 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: transporter; integral membrane protein YxzK 4110247 yxzK 8303163 yxzK Bacillus subtilis subsp. subtilis str. 168 integral membrane protein YxzK YP_003097798.1 4109843 D 224308 CDS NP_391882.3 255767863 937696 4110217..4110909 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4110909 yxaC 937696 yxaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391882.3 4110217 D 224308 CDS NP_391883.3 255767864 937700 complement(4110949..4111980) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 18326573, 9298659; Product type pe: enzyme; general stress protein 30 4111980 yxaB 937700 yxaB Bacillus subtilis subsp. subtilis str. 168 general stress protein 30 NP_391883.3 4110949 R 224308 CDS NP_391884.2 255767865 937708 complement(4112073..4113221) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 15771780; Product type e: enzyme; glycerate kinase 4113221 glxK 937708 glxK Bacillus subtilis subsp. subtilis str. 168 glycerate kinase NP_391884.2 4112073 R 224308 CDS NP_391885.1 16081057 937710 4113417..4114148 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7476858, 7642511, 8655507; Product type r: regulator; gluconate operon transcriptional repressor 4114148 gntR 937710 gntR Bacillus subtilis subsp. subtilis str. 168 gluconate operon transcriptional repressor NP_391885.1 4113417 D 224308 CDS NP_391886.1 16081058 937713 4114141..4115682 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11468405, 1659648, 3020045; Product type e: enzyme; gluconokinase 4115682 gntK 937713 gntK Bacillus subtilis subsp. subtilis str. 168 gluconokinase NP_391886.1 4114141 D 224308 CDS NP_391887.1 16081059 937715 4115711..4117057 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15849754, 1659648, 16850406, 3020045; Product type t: transporter; gluconate permease 4117057 gntP 937715 gntP Bacillus subtilis subsp. subtilis str. 168 gluconate permease NP_391887.1 4115711 D 224308 CDS NP_391888.1 16081060 937716 4117080..4118486 1 NC_000964.3 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 4118486 gntZ 937716 gntZ Bacillus subtilis subsp. subtilis str. 168 6-phosphogluconate dehydrogenase NP_391888.1 4117080 D 224308 CDS NP_391889.1 16081061 938147 4118950..4119513 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 8932315; Product type e: enzyme; alkyl hydroperoxide reductase subunit C 4119513 ahpC 938147 ahpC Bacillus subtilis subsp. subtilis str. 168 alkyl hydroperoxide reductase subunit C NP_391889.1 4118950 D 224308 CDS NP_391890.1 16081062 937717 4119527..4121056 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14766928, 16232966, 8932314; Product type e: enzyme; NADH dehydrogenase 4121056 ahpF 937717 ahpF Bacillus subtilis subsp. subtilis str. 168 NADH dehydrogenase NP_391890.1 4119527 D 224308 CDS NP_391891.1 16081063 937718 complement(4121166..4122605) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14652714; Product type e: enzyme; aryl-phospho-beta-d-glucosidase BglA 4122605 bglA 937718 bglA Bacillus subtilis subsp. subtilis str. 168 aryl-phospho-beta-d-glucosidase BglA NP_391891.1 4121166 R 224308 CDS NP_391892.1 16081064 937724 complement(4122619..4122849) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 12867744; Product type pt : transporter; PTS system transporter subunit IIA YyzE 4122849 yyzE 937724 yyzE Bacillus subtilis subsp. subtilis str. 168 PTS system transporter subunit IIA YyzE NP_391892.1 4122619 R 224308 CDS NP_391893.1 16081065 937726 4123193..4123903 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YydK 4123903 yydK 937726 yydK Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YydK NP_391893.1 4123193 D 224308 CDS YP_003097799.1 255767866 8302916 4123931..4124089 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 4124089 yyzN 8302916 yyzN Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097799.1 4123931 D 224308 CDS NP_391894.1 16081066 937730 complement(4124220..4124942) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type t: transporter; peptide export permease protein YydJ 4124942 yydJ 937730 yydJ Bacillus subtilis subsp. subtilis str. 168 peptide export permease protein YydJ NP_391894.1 4124220 R 224308 CDS NP_391895.1 16081067 937743 complement(4124963..4125592) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15743949, 17921301; Product type t: transporter; peptide export ATP-binding protein YydI 4125592 yydI 937743 yydI Bacillus subtilis subsp. subtilis str. 168 peptide export ATP-binding protein YydI NP_391895.1 4124963 R 224308 CDS NP_391896.2 255767867 937745 complement(4125742..4126500) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15743949, 15849754, 16850406, 17921301; Product type pt: transporter; peptide zinc metalloprotease protein YydH 4126500 yydH 937745 yydH Bacillus subtilis subsp. subtilis str. 168 peptide zinc metalloprotease protein YydH NP_391896.2 4125742 R 224308 CDS NP_391897.1 16081069 937720 complement(4126481..4127440) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17921301, 18307109; Product type pe: enzyme; peptide biosynthesis protein YydG 4127440 yydG 937720 yydG Bacillus subtilis subsp. subtilis str. 168 peptide biosynthesis protein YydG NP_391897.1 4126481 R 224308 CDS NP_391898.1 16081070 937753 complement(4127498..4127647) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 15101989, 17921301; Product type f: factor; hypothetical protein 4127647 yydF 937753 yydF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391898.1 4127498 R 224308 CDS NP_391899.1 16081071 937744 4128029..4130044 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 9696785; Product type e : enzyme; fructose-1,6-bisphosphatase 4130044 fbp 937744 fbp Bacillus subtilis subsp. subtilis str. 168 fructose-1,6-bisphosphatase NP_391899.1 4128029 D 224308 CDS NP_391900.1 16081072 937732 complement(4130578..4132338) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4132338 yydD 937732 yydD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391900.1 4130578 R 224308 CDS NP_391901.1 16081073 937731 complement(4132338..4132736) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4132736 yydC 937731 yydC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391901.1 4132338 R 224308 CDS NP_391902.1 16081074 937728 complement(4132729..4134174) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; metallophosphoesterase 4134174 yydB 937728 yydB Bacillus subtilis subsp. subtilis str. 168 metallophosphoesterase NP_391902.1 4132729 R 224308 CDS NP_391903.1 16081075 937752 complement(4134436..4134915) 1 NC_000964.3 SPOUT methyltransferase; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; ribosomal RNA large subunit methyltransferase H 4134915 yydA 937752 yydA Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA large subunit methyltransferase H NP_391903.1 4134436 R 224308 CDS YP_003097800.1 255767868 8303139 complement(4134996..4135166) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4135166 yyzF 8303139 yyzF Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097800.1 4134996 R 224308 CDS NP_391904.1 16081076 938490 4135351..4135764 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin; hypothetical protein 4135764 yycS 938490 yycS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391904.1 4135351 D 224308 CDS NP_391905.1 16081077 937754 complement(4135798..4137024) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; zinc-type alcohol dehydrogenase 4137024 yycR 937754 yycR Bacillus subtilis subsp. subtilis str. 168 zinc-type alcohol dehydrogenase NP_391905.1 4135798 R 224308 CDS YP_003097801.1 255767869 8303112 complement(4137087..4137257) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 4137257 yyzG 8303112 yyzG Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097801.1 4137087 R 224308 CDS NP_391906.1 16081078 937733 complement(4137362..4137610) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: membrane component; hypothetical protein 4137610 yycQ 937733 yycQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391906.1 4137362 R 224308 CDS NP_391907.2 255767870 937764 complement(4137626..4138789) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11557812, 16291680; hypothetical protein 4138789 yycP 937764 yycP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391907.2 4137626 R 224308 CDS NP_391908.1 16081080 937766 complement(4138800..4139537) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4139537 yycO 937766 yycO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391908.1 4138800 R 224308 CDS NP_391909.1 16081081 937725 complement(4139679..4140149) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14635137; Product type pe : enzyme; N-acetyltransferase YycN 4140149 yycN 937725 yycN Bacillus subtilis subsp. subtilis str. 168 N-acetyltransferase YycN NP_391909.1 4139679 R 224308 CDS NP_391910.1 16081082 937771 4140260..4141357 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878; Product type e: enzyme; response regulator aspartate phosphatase G 4141357 rapG 937771 rapG Bacillus subtilis subsp. subtilis str. 168 response regulator aspartate phosphatase G NP_391910.1 4140260 D 224308 CDS NP_391911.1 16081083 937767 4141358..4141474 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12950930, 16553878, 16816200; Product type r: regulator; phosphatase RapG inhibitor 4141474 phrG 937767 phrG Bacillus subtilis subsp. subtilis str. 168 phosphatase RapG inhibitor NP_391911.1 4141358 D 224308 CDS NP_391912.1 16081084 937760 complement(4141711..4142601) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 10931887, 7540694; Product type e: enzyme; arginase 4142601 argI 937760 argI Bacillus subtilis subsp. subtilis str. 168 arginase NP_391912.1 4141711 R 224308 CDS NP_391913.1 16081085 937761 complement(4142675..4144078) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10648515, 15849754, 16850406, 7540694; Product type t: transporter; amino acid permease RocE 4144078 rocE 937761 rocE Bacillus subtilis subsp. subtilis str. 168 amino acid permease RocE NP_391913.1 4142675 R 224308 CDS NP_391914.1 16081086 937755 complement(4144301..4145506) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 7540694, 9383188; Product type e: enzyme; ornithine aminotransferase 4145506 rocD 937755 rocD Bacillus subtilis subsp. subtilis str. 168 ornithine aminotransferase NP_391914.1 4144301 R 224308 CDS NP_391915.1 16081087 937769 4145747..4147132 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12533460, 12634342, 9194709; Product type r: regulator; arginine utilization regulatory protein RocR 4147132 rocR 937769 rocR Bacillus subtilis subsp. subtilis str. 168 arginine utilization regulatory protein RocR NP_391915.1 4145747 D 224308 CDS NP_391916.1 16081088 937779 complement(4147567..4148769) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 10692364, 11133960, 16030236; Product type pe: enzyme; serine protease YyxA 4148769 htrC 937779 htrC Bacillus subtilis subsp. subtilis str. 168 serine protease YyxA NP_391916.1 4147567 R 224308 CDS NP_391917.2 255767871 937778 complement(4148851..4149645) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16030236; Product type pe : enzyme; metallo-hydrolase YycJ 4149645 yycJ 937778 yycJ Bacillus subtilis subsp. subtilis str. 168 metallo-hydrolase YycJ NP_391917.2 4148851 R 224308 CDS NP_391918.1 16081090 937765 complement(4149667..4150509) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 17307848, 17307850; Product type r: regulator; two-component system YycFG regulatory protein 4150509 yycI 937765 yycI Bacillus subtilis subsp. subtilis str. 168 two-component system YycFG regulatory protein NP_391918.1 4149667 R 224308 CDS NP_391919.1 16081091 937790 complement(4150496..4151863) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16030236, 16600972, 17307850; Product type r: regulator; two-component system YycF/YycG regulatory protein YycH 4151863 walH 937790 walH Bacillus subtilis subsp. subtilis str. 168 two-component system YycF/YycG regulatory protein YycH NP_391919.1 4150496 R 224308 CDS NP_391920.1 16081092 937793 complement(4151853..4153688) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 19019149; Product type rc: receptor; sensor histidine kinase 4153688 walK 937793 walK Bacillus subtilis subsp. subtilis str. 168 sensor histidine kinase NP_391920.1 4151853 R 224308 CDS NP_391921.1 16081093 937776 complement(4153696..4154403) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10878122, 12682299, 15015732, 15153768, 17307850, 17370266, 18789936, 19019149; Product type r: regulator; transcriptional regulator 4154403 walR 937776 walR Bacillus subtilis subsp. subtilis str. 168 transcriptional regulator NP_391921.1 4153696 R 224308 CDS NP_391922.1 16081094 937805 complement(4155433..4156725) 1 NC_000964.3 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 4156725 purA 937805 purA Bacillus subtilis subsp. subtilis str. 168 adenylosuccinate synthetase NP_391922.1 4155433 R 224308 CDS NP_391923.1 16081095 937806 complement(4156931..4157350) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4157350 yycE 937806 yycE Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391923.1 4156931 R 224308 CDS NP_391924.2 255767872 937810 complement(4157471..4158835) 1 NC_000964.3 unwinds double stranded DNA; replicative DNA helicase 4158835 dnaC 937810 dnaC Bacillus subtilis subsp. subtilis str. 168 replicative DNA helicase NP_391924.2 4157471 R 224308 CDS NP_391925.1 16081097 937781 4159005..4159205 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4159205 yycD 937781 yycD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391925.1 4159005 D 224308 CDS NP_391926.1 16081098 937821 complement(4159253..4159456) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; hypothetical protein 4159456 yyzB 937821 yyzB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391926.1 4159253 R 224308 CDS NP_391927.1 16081099 937823 4159577..4159717 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4159717 yycC 937823 yycC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391927.1 4159577 D 224308 CDS NP_391928.1 16081100 937777 4159790..4160998 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4160998 yycB 937777 yycB Bacillus subtilis subsp. subtilis str. 168 transporter NP_391928.1 4159790 D 224308 CDS NP_391929.2 255767873 937828 4161103..4163160 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pe: enzyme; mannosyltransferase YycA 4163160 yycA 937828 yycA Bacillus subtilis subsp. subtilis str. 168 mannosyltransferase YycA NP_391929.2 4161103 D 224308 CDS NP_391930.1 16081102 937830 complement(4163197..4163646) 1 NC_000964.3 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 4163646 rplI 937830 rplI Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L9 NP_391930.1 4163197 R 224308 CDS NP_391931.1 16081103 937816 complement(4163643..4165622) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4165622 yybT 937816 yybT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391931.1 4163643 R 224308 CDS NP_391932.1 16081104 937844 complement(4165659..4166588) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4166588 yybS 937844 yybS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391932.1 4165659 R 224308 CDS YP_003097802.1 255767874 8302993 complement(4166815..4166964) 1 NC_000964.3 Evidence 5: No homology to any previously reported sequences; membrane protein 4166964 yyzH 8302993 yyzH Bacillus subtilis subsp. subtilis str. 168 membrane protein YP_003097802.1 4166815 R 224308 CDS NP_391933.1 16081105 936671 4167110..4167592 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 1708381; Product type f : factor; spore coat protein F 4167592 cotF 936671 cotF Bacillus subtilis subsp. subtilis str. 168 spore coat protein F NP_391933.1 4167110 D 224308 CDS NP_391934.1 16081106 937825 complement(4167622..4167999) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybR 4167999 yybR 937825 yybR Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YybR NP_391934.1 4167622 R 224308 CDS NP_391935.1 16081107 937817 4168204..4169133 1 NC_000964.3 catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase 4169133 ppaC 937817 ppaC Bacillus subtilis subsp. subtilis str. 168 manganese-dependent inorganic pyrophosphatase NP_391935.1 4168204 D 224308 CDS NP_391936.1 16081108 937851 complement(4169166..4169612) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15096624; Product type pt : transporter; lipoprotein 4169612 yybP 937851 yybP Bacillus subtilis subsp. subtilis str. 168 lipoprotein NP_391936.1 4169166 R 224308 CDS NP_391937.1 16081109 937836 4170045..4171352 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4171352 yybO 937836 yybO Bacillus subtilis subsp. subtilis str. 168 transporter NP_391937.1 4170045 D 224308 CDS NP_391938.1 16081110 937850 4173114..4173551 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4173551 yybN 937850 yybN Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391938.1 4173114 D 224308 CDS NP_391939.1 16081111 937824 4173665..4174420 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4174420 yybM 937824 yybM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391939.1 4173665 D 224308 CDS NP_391940.1 16081112 936529 4174410..4175120 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4175120 yybL 936529 yybL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391940.1 4174410 D 224308 CDS NP_391941.1 16081113 938116 4175117..4175872 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4175872 yybK 938116 yybK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391941.1 4175117 D 224308 CDS NP_391942.1 16081114 937807 4175869..4176525 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 1938973; Product type pe : enzyme; ABC transporter ATP-binding protein 4176525 yybJ 937807 yybJ Bacillus subtilis subsp. subtilis str. 168 ABC transporter ATP-binding protein NP_391942.1 4175869 D 224308 CDS NP_391943.1 16081115 937811 complement(4176900..4177688) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16321932; Product type cp: cell process; hypothetical protein 4177688 yybI 937811 yybI Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391943.1 4176900 R 224308 CDS NP_391944.1 16081116 937866 complement(4177756..4178145) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4178145 yybH 937866 yybH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391944.1 4177756 R 224308 CDS NP_391945.1 16081117 937852 4178291..4179130 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 11709313; hypothetical protein 4179130 yybG 937852 yybG Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391945.1 4178291 D 224308 CDS NP_391946.1 16081118 937854 complement(4179163..4180377) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9811656; Product type pt: transporter; MFS transporter 4180377 yybF 937854 yybF Bacillus subtilis subsp. subtilis str. 168 MFS transporter NP_391946.1 4179163 R 224308 CDS NP_391947.2 255767875 937875 4180564..4181442 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybE 4181442 yybE 937875 yybE Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YybE NP_391947.2 4180564 D 224308 CDS NP_391948.1 16081120 938072 4181456..4181899 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4181899 yybD 938072 yybD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391948.1 4181456 D 224308 CDS NP_391949.1 16081121 937862 4181982..4182461 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4182461 yybC 937862 yybC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391949.1 4181982 D 224308 CDS NP_391950.1 16081122 937880 complement(4182636..4183298) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4183298 yybB 937880 yybB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391950.1 4182636 R 224308 CDS NP_391951.1 16081123 937872 complement(4183445..4183897) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: regulator; HTH-type transcriptional regulator YybA 4183897 yybA 937872 yybA Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YybA NP_391951.1 4183445 R 224308 CDS NP_391952.1 16081124 937874 4184017..4184463 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4184463 yyaT 937874 yyaT Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391952.1 4184017 D 224308 CDS NP_391953.1 16081125 937921 4184460..4185065 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4185065 yyaS 937921 yyaS Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391953.1 4184460 D 224308 CDS NP_391954.1 16081126 937878 complement(4185160..4185681) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 16579456; Product type pe : enzyme; hypothetical protein 4185681 yyaR 937878 yyaR Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391954.1 4185160 R 224308 CDS NP_391955.1 16081127 937883 4186092..4186448 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4186448 yyaQ 937883 yyaQ Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391955.1 4186092 D 224308 CDS NP_391956.1 16081128 937903 4186608..4187174 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4187174 yyaP 937903 yyaP Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391956.1 4186608 D 224308 CDS NP_391957.1 16081129 937890 complement(4187681..4189057) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 14636065, 15849754, 16850406, 17015648, 7961647; Product type t : transporter; tetracycline resistance protein 4189057 tetB 937890 tetB Bacillus subtilis subsp. subtilis str. 168 tetracycline resistance protein NP_391957.1 4187681 R 224308 CDS NP_391959.1 16081131 937882 4189406..4189645 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4189645 yyaO 937882 yyaO Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391959.1 4189406 D 224308 CDS NP_391960.1 16081132 937892 4189796..4190212 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 14663075; Product type pr : regulator; HTH-type transcriptional regulator YyaN 4190212 yyaN 937892 yyaN Bacillus subtilis subsp. subtilis str. 168 HTH-type transcriptional regulator YyaN NP_391960.1 4189796 D 224308 CDS NP_391961.1 16081133 937895 4190209..4191126 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pt: transporter; transporter 4191126 yyaM 937895 yyaM Bacillus subtilis subsp. subtilis str. 168 transporter NP_391961.1 4190209 D 224308 CDS NP_391962.1 16081134 937904 4191198..4193267 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4193267 yyaL 937904 yyaL Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391962.1 4191198 D 224308 CDS NP_391963.1 16081135 937893 complement(4193264..4194163) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4194163 yyaK 937893 yyaK Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391963.1 4193264 R 224308 CDS NP_391964.2 255767876 937884 4194389..4195744 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406, 9529885; Product type pt: transporter; metabolite transport protein YyaJ 4195744 yyaJ 937884 yyaJ Bacillus subtilis subsp. subtilis str. 168 metabolite transport protein YyaJ NP_391964.2 4194389 D 224308 CDS NP_391965.1 16081137 937913 complement(4195778..4196332) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12731863, 12793527; Product type e: enzyme; maltose O-acetyltransferase 4196332 maa 937913 maa Bacillus subtilis subsp. subtilis str. 168 maltose O-acetyltransferase NP_391965.1 4195778 R 224308 CDS NP_391966.1 16081138 937879 complement(4196350..4196730) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: enzyme; hypothetical protein 4196730 yyaH 937879 yyaH Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391966.1 4196350 R 224308 CDS NP_391967.1 16081139 937876 complement(4196786..4197721) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 16267306, 9457849, 9642180; Product type r: regulator; catabolite control protein B 4197721 ccpB 937876 ccpB Bacillus subtilis subsp. subtilis str. 168 catabolite control protein B NP_391967.1 4196786 R 224308 CDS NP_391968.1 16081140 937918 complement(4197780..4198538) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 10540738, 16237020, 18203828; Product type e: enzyme; exodeoxyribonuclease 4198538 exoAA 937918 exoAA Bacillus subtilis subsp. subtilis str. 168 exodeoxyribonuclease NP_391968.1 4197780 R 224308 CDS NP_391969.2 50812313 937906 complement(4198603..4198842) 1 NC_000964.3 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 4198842 rpsR 937906 rpsR Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S18 NP_391969.2 4198603 R 224308 CDS NP_391970.1 16081142 937911 complement(4198886..4199404) 1 NC_000964.3 Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; PubMedId: 12682299, 14762004, 16549871, 10072765; Product type f: factor; single-stranded DNA-binding protein 4199404 ssbA 937911 ssbA Bacillus subtilis subsp. subtilis str. 168 single-stranded DNA-binding protein NP_391970.1 4198886 R 224308 CDS NP_391971.1 16081143 937919 complement(4199445..4199732) 1 NC_000964.3 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 4199732 rpsF 937919 rpsF Bacillus subtilis subsp. subtilis str. 168 30S ribosomal protein S6 NP_391971.1 4199445 R 224308 CDS NP_391972.1 16081144 937916 complement(4199843..4200943) 1 NC_000964.3 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 4200943 yyaF 937916 yyaF Bacillus subtilis subsp. subtilis str. 168 GTP-dependent nucleic acid-binding protein EngD NP_391972.1 4199843 R 224308 CDS NP_391973.1 16081145 937914 complement(4201070..4203073) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 17114254; Product type pe : enzyme; oxidoreductase 4203073 yyaE 937914 yyaE Bacillus subtilis subsp. subtilis str. 168 oxidoreductase NP_391973.1 4201070 R 224308 CDS YP_003097803.1 255767877 8302952 complement(4203124..4203330) 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4203330 yyzM 8302952 yyzM Bacillus subtilis subsp. subtilis str. 168 hypothetical protein YP_003097803.1 4203124 R 224308 CDS NP_391974.1 16081146 937923 complement(4203424..4204440) 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16847258, 16850406; Product type pt: transporter; hypothetical protein 4204440 yyaD 937923 yyaD Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391974.1 4203424 R 224308 CDS NP_391975.1 16081147 937925 4204900..4205517 1 NC_000964.3 Evidence 4: Homologs of previously reported genes of unknown function; hypothetical protein 4205517 yyaC 937925 yyaC Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391975.1 4204900 D 224308 CDS NP_391976.1 16081148 937907 complement(4205556..4206404) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298; Product type f : factor; stage 0 sporulation protein J 4206404 parB 937907 parB Bacillus subtilis subsp. subtilis str. 168 stage 0 sporulation protein J NP_391976.1 4205556 R 224308 CDS NP_391977.1 16081149 937928 complement(4206397..4207158) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11532141, 12950914, 15659156, 15774898, 15998739, 16677298, 18077387; Product type f: factor; sporulation initiation inhibitor protein Soj 4207158 parA 937928 parA Bacillus subtilis subsp. subtilis str. 168 sporulation initiation inhibitor protein Soj NP_391977.1 4206397 R 224308 CDS NP_391978.2 255767878 937929 4207406..4207846 1 NC_000964.3 Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId: 15849754, 16850406; Product type pm: membrane component; hypothetical protein 4207846 yyaB 937929 yyaB Bacillus subtilis subsp. subtilis str. 168 hypothetical protein NP_391978.2 4207406 D 224308 CDS NP_391979.1 16081151 937920 complement(4207897..4208748) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 11807071, 15210112, 16549676; Product type f: factor; nucleoid occlusion protein 4208748 noc 937920 noc Bacillus subtilis subsp. subtilis str. 168 nucleoid occlusion protein NP_391979.1 4207897 R 224308 CDS NP_391980.1 16081152 937931 complement(4208870..4209589) 1 NC_000964.3 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; ribosomal RNA small subunit methyltransferase G 4209589 gidB 937931 gidB Bacillus subtilis subsp. subtilis str. 168 ribosomal RNA small subunit methyltransferase G NP_391980.1 4208870 R 224308 CDS NP_391981.1 16081153 937932 complement(4209603..4211489) 1 NC_000964.3 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG 4211489 gidA 937932 gidA Bacillus subtilis subsp. subtilis str. 168 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG NP_391981.1 4209603 R 224308 CDS NP_391982.1 16081154 937927 complement(4211510..4212889) 1 NC_000964.3 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase MnmE 4212889 trmE 937927 trmE Bacillus subtilis subsp. subtilis str. 168 tRNA modification GTPase MnmE NP_391982.1 4211510 R 224308 CDS NP_391983.1 16081155 937933 complement(4213200..4213826) 1 NC_000964.3 Evidence 1a: Function experimentally demonstrated in the studied strain; PubMedId: 12813085, 1487728; Product type f: factor; protein jag 4213826 jag 937933 jag Bacillus subtilis subsp. subtilis str. 168 protein jag NP_391983.1 4213200 R 224308 CDS NP_391984.1 16081156 937934 complement(4213823..4214608) 1 NC_000964.3 involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; necessary for sporulation; membrane protein insertase MisCA 4214608 spoIIIJ 937934 spoIIIJ Bacillus subtilis subsp. subtilis str. 168 membrane protein insertase MisCA NP_391984.1 4213823 R 224308 CDS NP_391985.1 16081157 937930 complement(4214753..4215103) 1 NC_000964.3 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P protein component 4215103 rnpA 937930 rnpA Bacillus subtilis subsp. subtilis str. 168 ribonuclease P protein component NP_391985.1 4214753 R 224308 CDS NP_391986.1 16081158 937942 complement(4215255..4215389) 1 NC_000964.3 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 4215389 rpmH 937942 rpmH Bacillus subtilis subsp. subtilis str. 168 50S ribosomal protein L34 NP_391986.1 4215255 R 224308 CDS