-- dump date 20140620_084440 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 516950000001 SEQ_END SEQ_END NC_010582.1 2209198 2209198 DR NC_010582.1; contig end 2209198..2209198 Streptococcus pneumoniae CGSP14 YP_001834718.1 CDS dnaA NC_010582.1 197 1558 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 197..1558 Streptococcus pneumoniae CGSP14 6217988 YP_001834719.1 CDS dnaN NC_010582.1 1717 2853 D binds the polymerase to DNA and acts as a sliding clamp; DNA polymerase III subunit beta 1717..2853 Streptococcus pneumoniae CGSP14 6217096 YP_001834720.1 CDS SPCG_0003 NC_010582.1 2864 3112 D hypothetical protein 2864..3112 Streptococcus pneumoniae CGSP14 6218106 YP_001834721.1 CDS SPCG_0004 NC_010582.1 3187 4311 D translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 3187..4311 Streptococcus pneumoniae CGSP14 6217056 YP_001834722.1 CDS pth NC_010582.1 4382 4951 D Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 4382..4951 Streptococcus pneumoniae CGSP14 6216548 YP_001834723.1 CDS mfd NC_010582.1 4952 8461 D transcription-repair coupling factor 4952..8461 Streptococcus pneumoniae CGSP14 6217213 YP_001834724.1 CDS SPCG_0007 NC_010582.1 8519 8785 D S4 domain-containing protein 8519..8785 Streptococcus pneumoniae CGSP14 6217872 YP_001834725.1 CDS SPCG_0008 NC_010582.1 8778 9146 D hypothetical protein 8778..9146 Streptococcus pneumoniae CGSP14 6218256 YP_001834726.1 CDS SPCG_0009 NC_010582.1 9197 10534 D hypothetical protein 9197..10534 Streptococcus pneumoniae CGSP14 6217895 YP_001834727.1 CDS SPCG_0010 NC_010582.1 10531 11808 D mesJ/ycf62 family protein 10531..11808 Streptococcus pneumoniae CGSP14 6217938 YP_001834728.1 CDS hgt NC_010582.1 11812 12354 D hypoxanthine-guanine phosphoribosyltransferase 11812..12354 Streptococcus pneumoniae CGSP14 6218208 YP_001834729.1 CDS ftsH NC_010582.1 12370 14328 D cell division protein FtsH 12370..14328 Streptococcus pneumoniae CGSP14 6217470 YP_001834730.1 CDS comX1 NC_010582.1 14450 14929 D transcriptional regulator ComX1 14450..14929 Streptococcus pneumoniae CGSP14 6217343 YP_001834731.1 CDS SPCG_0014 NC_010582.1 20396 20743 D IS630-Spn1, transposase Orf1 20396..20743 Streptococcus pneumoniae CGSP14 6218358 YP_001834732.1 CDS SPCG_0015 NC_010582.1 21451 21588 D hypothetical protein 21451..21588 Streptococcus pneumoniae CGSP14 6217131 YP_001834733.1 CDS SPCG_0016 NC_010582.1 21494 21598 R hypothetical protein complement(21494..21598) Streptococcus pneumoniae CGSP14 6216806 YP_001834734.1 CDS SPCG_0017 NC_010582.1 21822 22028 R hypothetical protein complement(21822..22028) Streptococcus pneumoniae CGSP14 6216591 YP_001834735.1 CDS SPCG_0018 NC_010582.1 22338 22580 D hypothetical protein 22338..22580 Streptococcus pneumoniae CGSP14 6217393 YP_001834736.1 CDS purA NC_010582.1 22769 24097 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 22769..24097 Streptococcus pneumoniae CGSP14 6218204 YP_001834737.1 CDS SPCG_0020 NC_010582.1 24298 24765 D cytidine/deoxycytidylate deaminase family protein 24298..24765 Streptococcus pneumoniae CGSP14 6216687 YP_001834738.1 CDS dut NC_010582.1 24951 25394 D catalyzes the formation of dUMP from dUTP; deoxyuridine 5'-triphosphate nucleotidohydrolase 24951..25394 Streptococcus pneumoniae CGSP14 6216809 YP_001834739.1 CDS SPCG_0022 NC_010582.1 25354 25911 D hypothetical protein 25354..25911 Streptococcus pneumoniae CGSP14 6217586 YP_001834740.1 CDS radA NC_010582.1 26024 27286 D Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 26024..27286 Streptococcus pneumoniae CGSP14 6217224 YP_001834741.1 CDS SPCG_0024 NC_010582.1 27290 27856 D hypothetical protein 27290..27856 Streptococcus pneumoniae CGSP14 6216566 YP_001834742.1 CDS SPCG_0025 NC_010582.1 27877 28221 D hypothetical protein 27877..28221 Streptococcus pneumoniae CGSP14 6216463 YP_001834743.1 CDS SPCG_0026 NC_010582.1 28203 28754 D hypothetical protein 28203..28754 Streptococcus pneumoniae CGSP14 6217960 YP_001834744.1 CDS SPCG_0027 NC_010582.1 28730 29569 D IS3-Spn1, transposase 28730..29569 Streptococcus pneumoniae CGSP14 6216711 YP_001834745.1 CDS SPCG_0028 NC_010582.1 29575 30135 D repair protein 29575..30135 Streptococcus pneumoniae CGSP14 6217011 YP_001834746.1 CDS prsA NC_010582.1 30229 31248 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 30229..31248 Streptococcus pneumoniae CGSP14 6217204 YP_001834747.1 CDS SPCG_0030 NC_010582.1 31366 31719 D hypothetical protein 31366..31719 Streptococcus pneumoniae CGSP14 6217998 YP_001834748.1 CDS SPCG_0031 NC_010582.1 31938 32120 D competence-induced protein Ccs16 31938..32120 Streptococcus pneumoniae CGSP14 6216459 YP_001834749.1 CDS polA NC_010582.1 32865 35534 D has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 32865..35534 Streptococcus pneumoniae CGSP14 6218058 YP_001834750.1 CDS SPCG_0033 NC_010582.1 35619 36056 D hypothetical protein 35619..36056 Streptococcus pneumoniae CGSP14 6216513 YP_001834751.1 CDS SPCG_0034 NC_010582.1 35958 36563 R hypothetical protein complement(35958..36563) Streptococcus pneumoniae CGSP14 6216871 YP_001834752.1 CDS SPCG_0035 NC_010582.1 36511 37533 R membrane protein complement(36511..37533) Streptococcus pneumoniae CGSP14 6217805 YP_001834753.1 CDS SPCG_0036 NC_010582.1 37670 38839 D catalyzes the transamination of the aromatic amino acid forming a ketoacid; first step in aromatic amino acid degradation in lactococci; aromatic amino acid aminotransferase 37670..38839 Streptococcus pneumoniae CGSP14 6216531 YP_001834754.1 CDS SPCG_0037 NC_010582.1 38770 39486 R hypothetical protein complement(38770..39486) Streptococcus pneumoniae CGSP14 6216885 YP_001834755.1 CDS recO NC_010582.1 38836 39606 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 38836..39606 Streptococcus pneumoniae CGSP14 6216507 YP_001834756.1 CDS plsX NC_010582.1 39603 40595 D involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 39603..40595 Streptococcus pneumoniae CGSP14 6216645 YP_001834757.1 CDS acpP NC_010582.1 40601 40834 D acyl carrier protein 40601..40834 Streptococcus pneumoniae CGSP14 6217801 YP_001834758.1 CDS SPCG_0041 NC_010582.1 40877 40969 D degenerate transposase 40877..40969 Streptococcus pneumoniae CGSP14 6216829 YP_001834759.1 CDS SPCG_0042 NC_010582.1 41079 41171 D degenerate transposase 41079..41171 Streptococcus pneumoniae CGSP14 6218182 YP_001834760.1 CDS SPCG_0043 NC_010582.1 41373 41603 D bacteriocin BlpU 41373..41603 Streptococcus pneumoniae CGSP14 6216830 YP_001834761.1 CDS comA NC_010582.1 42291 44471 D competence factor transporting ATP-binding protein/permease ComA 42291..44471 Streptococcus pneumoniae CGSP14 6217909 YP_001834762.1 CDS comB NC_010582.1 44484 45833 D competence factor transport protein ComB 44484..45833 Streptococcus pneumoniae CGSP14 6217322 YP_001834763.1 CDS purC NC_010582.1 45961 46710 D catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase 45961..46710 Streptococcus pneumoniae CGSP14 6216461 YP_001834764.1 CDS purL NC_010582.1 46909 50637 D phosphoribosylformylglycinamidine synthase 46909..50637 Streptococcus pneumoniae CGSP14 6216689 YP_001834765.1 CDS purF NC_010582.1 50730 52172 D Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 50730..52172 Streptococcus pneumoniae CGSP14 6217300 YP_001834766.1 CDS purM NC_010582.1 52209 53231 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 52209..53231 Streptococcus pneumoniae CGSP14 6217762 YP_001834767.1 CDS purN NC_010582.1 53228 53773 D glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate; phosphoribosylglycinamide formyltransferase 53228..53773 Streptococcus pneumoniae CGSP14 6217005 YP_001834768.1 CDS vanZ NC_010582.1 53857 54366 D vanZ protein 53857..54366 Streptococcus pneumoniae CGSP14 6218179 YP_001834769.1 CDS purH NC_010582.1 54370 55938 D involved in de novo purine biosynthesis; bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 54370..55938 Streptococcus pneumoniae CGSP14 6217203 YP_001834770.1 CDS purD NC_010582.1 56060 57322 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 56060..57322 Streptococcus pneumoniae CGSP14 6217176 YP_001834771.1 CDS SPCG_0054 NC_010582.1 57579 57695 D hypothetical protein 57579..57695 Streptococcus pneumoniae CGSP14 6218509 YP_001834772.1 CDS purE NC_010582.1 57692 58213 D phosphoribosylaminoimidazole carboxylase catalytic subunit 57692..58213 Streptococcus pneumoniae CGSP14 6217140 YP_001834773.1 CDS purK NC_010582.1 58161 59291 D With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway; phosphoribosylaminoimidazole carboxylase ATPase subunit 58161..59291 Streptococcus pneumoniae CGSP14 6216646 YP_001834774.1 CDS SPCG_0057 NC_010582.1 59301 59528 D hypothetical protein 59301..59528 Streptococcus pneumoniae CGSP14 6216617 YP_001834775.1 CDS purB NC_010582.1 59591 60889 D Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 59591..60889 Streptococcus pneumoniae CGSP14 6216808 YP_001834776.1 CDS strH NC_010582.1 60944 64969 R beta-N-acetylhexosaminidase complement(60944..64969) Streptococcus pneumoniae CGSP14 6217476 YP_001834777.1 CDS SPCG_0060 NC_010582.1 65196 65954 R GntR family transcriptional regulator complement(65196..65954) Streptococcus pneumoniae CGSP14 6216564 YP_001834778.1 CDS bgaC NC_010582.1 66260 68047 D beta-galactosidase 66260..68047 Streptococcus pneumoniae CGSP14 6216780 YP_001834779.1 CDS SPCG_0062 NC_010582.1 68044 68520 D PTS system transporter subunit IIB 68044..68520 Streptococcus pneumoniae CGSP14 6217134 YP_001834780.1 CDS SPCG_0063 NC_010582.1 68548 69453 D PTS system transporter subunit IIC 68548..69453 Streptococcus pneumoniae CGSP14 6217406 YP_001834781.1 CDS SPCG_0064 NC_010582.1 69425 70255 D PTS system transporter subunit IID 69425..70255 Streptococcus pneumoniae CGSP14 6216661 YP_001834782.1 CDS SPCG_0065 NC_010582.1 70262 70666 D PTS system transporter subunit IIA 70262..70666 Streptococcus pneumoniae CGSP14 6218180 YP_001834783.1 CDS agaS NC_010582.1 70964 72124 D sugar isomerase 70964..72124 Streptococcus pneumoniae CGSP14 6217336 YP_001834784.1 CDS galM NC_010582.1 72246 73283 D aldose 1-epimerase 72246..73283 Streptococcus pneumoniae CGSP14 6218128 YP_001834785.1 CDS SPCG_0068 NC_010582.1 73490 74344 D hypothetical protein 73490..74344 Streptococcus pneumoniae CGSP14 6218333 YP_001834786.1 CDS SPCG_0069 NC_010582.1 74494 74751 D hypothetical protein 74494..74751 Streptococcus pneumoniae CGSP14 6217804 YP_001834787.1 CDS SPCG_0070 NC_010582.1 75209 75505 R rhodanese-like domain-containing protein complement(75209..75505) Streptococcus pneumoniae CGSP14 6216504 YP_001834788.1 CDS SPCG_0071 NC_010582.1 75495 75614 R hypothetical protein complement(75495..75614) Streptococcus pneumoniae CGSP14 6218221 YP_001834789.1 CDS SPCG_0072 NC_010582.1 75726 76490 D phosphorylase Pnp/Udp family protein 75726..76490 Streptococcus pneumoniae CGSP14 6216671 YP_001834790.1 CDS SPCG_0073 NC_010582.1 76746 76886 D hypothetical protein 76746..76886 Streptococcus pneumoniae CGSP14 6218389 YP_001834791.1 CDS trkH NC_010582.1 77055 78434 D Trk family potassium uptake protein 77055..78434 Streptococcus pneumoniae CGSP14 6218215 YP_001834792.1 CDS trkA NC_010582.1 78427 79113 D Trk family potassium uptake protein 78427..79113 Streptococcus pneumoniae CGSP14 6217363 YP_001834793.1 CDS SPCG_0076 NC_010582.1 79248 79451 D hypothetical protein 79248..79451 Streptococcus pneumoniae CGSP14 6216549 YP_001834794.1 CDS SPCG_0077 NC_010582.1 79513 80052 D hypothetical protein 79513..80052 Streptococcus pneumoniae CGSP14 6216763 YP_001834795.1 CDS SPCG_0079 NC_010582.1 79930 80499 R hypothetical protein complement(79930..80499) Streptococcus pneumoniae CGSP14 6217413 YP_001834796.1 CDS SPCG_0078 NC_010582.1 80119 80529 D hypothetical protein 80119..80529 Streptococcus pneumoniae CGSP14 6216586 YP_001834797.1 CDS SPCG_0080 NC_010582.1 80721 84131 D cell wall surface anchor family protein 80721..84131 Streptococcus pneumoniae CGSP14 6217051 YP_001834798.1 CDS SPCG_0081 NC_010582.1 84298 84996 D DNA-binding response regulator 84298..84996 Streptococcus pneumoniae CGSP14 6216361 YP_001834799.1 CDS SPCG_0082 NC_010582.1 84993 86045 D sensor histidine kinase 84993..86045 Streptococcus pneumoniae CGSP14 6217048 YP_001834800.1 CDS rpsD NC_010582.1 86240 86851 D primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination; 30S ribosomal protein S4 86240..86851 Streptococcus pneumoniae CGSP14 6216729 YP_001834801.1 CDS SPCG_0084 NC_010582.1 87072 87167 R hypothetical protein complement(87072..87167) Streptococcus pneumoniae CGSP14 6217248 YP_001834802.1 CDS SPCG_0085 NC_010582.1 87238 87507 D hypothetical protein 87238..87507 Streptococcus pneumoniae CGSP14 6217999 YP_001834803.1 CDS SPCG_0086 NC_010582.1 87587 87682 D hypothetical protein 87587..87682 Streptococcus pneumoniae CGSP14 6216981 YP_001834804.1 CDS SPCG_0087 NC_010582.1 87971 88930 D ABC transporter permease 87971..88930 Streptococcus pneumoniae CGSP14 6216842 YP_001834805.1 CDS SPCG_0088 NC_010582.1 88893 89867 D ABC transporter permease 88893..89867 Streptococcus pneumoniae CGSP14 6217903 YP_001834806.1 CDS SPCG_0089 NC_010582.1 89908 91446 D ABC transporter substrate-binding protein 89908..91446 Streptococcus pneumoniae CGSP14 6217165 YP_001834807.1 CDS SPCG_0090 NC_010582.1 91718 92704 D hypothetical protein 91718..92704 Streptococcus pneumoniae CGSP14 6217459 YP_001834808.1 CDS SPCG_0091 NC_010582.1 92886 93839 D hypothetical protein 92886..93839 Streptococcus pneumoniae CGSP14 6216832 YP_001834809.1 CDS SPCG_0092 NC_010582.1 93911 94975 R hypothetical protein complement(93911..94975) Streptococcus pneumoniae CGSP14 6217955 YP_001834810.1 CDS SPCG_0093 NC_010582.1 95038 96000 R hypothetical protein complement(95038..96000) Streptococcus pneumoniae CGSP14 6217187 YP_001834811.1 CDS SPCG_0094 NC_010582.1 95942 96535 R hypothetical protein complement(95942..96535) Streptococcus pneumoniae CGSP14 6217233 YP_001834812.1 CDS SPCG_0095 NC_010582.1 96522 96848 R hypothetical protein complement(96522..96848) Streptococcus pneumoniae CGSP14 6217599 YP_001834813.1 CDS SPCG_0096 NC_010582.1 96987 98153 R transporter complement(96987..98153) Streptococcus pneumoniae CGSP14 6217027 YP_001834814.1 CDS SPCG_0097 NC_010582.1 98211 99368 D glycosyl transferase family protein 98211..99368 Streptococcus pneumoniae CGSP14 6216970 YP_001834815.1 CDS SPCG_0098 NC_010582.1 99410 101260 D capsular polysaccharide biosynthesis protein 99410..101260 Streptococcus pneumoniae CGSP14 6216716 YP_001834816.1 CDS SPCG_0099 NC_010582.1 101346 101603 R hypothetical protein complement(101346..101603) Streptococcus pneumoniae CGSP14 6217206 YP_001834817.1 CDS SPCG_0100 NC_010582.1 101653 102285 R HAD superfamily hydrolase complement(101653..102285) Streptococcus pneumoniae CGSP14 6217230 YP_001834818.1 CDS SPCG_0101 NC_010582.1 102307 103179 R L-serine dehydratase, iron-sulfur-dependent subunit alpha complement(102307..103179) Streptococcus pneumoniae CGSP14 6217058 YP_001834819.1 CDS SPCG_0102 NC_010582.1 103188 103859 R L-serine dehydratase, iron-sulfur-dependent subunit beta complement(103188..103859) Streptococcus pneumoniae CGSP14 6217020 YP_001834820.1 CDS SPCG_0103 NC_010582.1 104101 104688 D lysM domain-containing protein 104101..104688 Streptococcus pneumoniae CGSP14 6216471 YP_001834821.1 CDS SPCG_0104 NC_010582.1 104740 105060 R hypothetical protein complement(104740..105060) Streptococcus pneumoniae CGSP14 6216590 YP_001834822.1 CDS SPCG_0105 NC_010582.1 105486 105773 D bacteriocin 105486..105773 Streptococcus pneumoniae CGSP14 6216990 YP_001834823.1 CDS SPCG_0106 NC_010582.1 105792 107933 D hypothetical protein 105792..107933 Streptococcus pneumoniae CGSP14 6217679 YP_001834824.1 CDS SPCG_0107 NC_010582.1 107930 108571 D amino acid ABC transporter ATP-binding protein 107930..108571 Streptococcus pneumoniae CGSP14 6216805 YP_001834825.1 CDS SPCG_0108 NC_010582.1 108676 109584 D amino acid ABC transporter periplasmic amino acid-binding protein 108676..109584 Streptococcus pneumoniae CGSP14 6218028 YP_001834826.1 CDS SPCG_0109 NC_010582.1 109550 110020 D argininosuccinate synthase, truncation 109550..110020 Streptococcus pneumoniae CGSP14 6216710 YP_001834827.1 CDS SPCG_0110 NC_010582.1 110309 111208 R hypothetical protein complement(110309..111208) Streptococcus pneumoniae CGSP14 6216848 YP_001834828.1 CDS SPCG_0111 NC_010582.1 111626 111976 D transporter truncation 111626..111976 Streptococcus pneumoniae CGSP14 6217397 YP_001834829.1 CDS SPCG_0112 NC_010582.1 111954 112325 D hypothetical protein 111954..112325 Streptococcus pneumoniae CGSP14 6217023 YP_001834830.1 CDS SPCG_0113 NC_010582.1 112919 113044 D hypothetical protein 112919..113044 Streptococcus pneumoniae CGSP14 6218027 YP_001834831.1 CDS SPCG_0114 NC_010582.1 113427 114485 D hypothetical protein 113427..114485 Streptococcus pneumoniae CGSP14 6216980 YP_001834832.1 CDS SPCG_0115 NC_010582.1 114800 115777 D hypothetical protein 114800..115777 Streptococcus pneumoniae CGSP14 6217607 YP_001834833.1 CDS SPCG_0116 NC_010582.1 116135 116509 D hypothetical protein 116135..116509 Streptococcus pneumoniae CGSP14 6217627 YP_001834834.1 CDS SPCG_0117 NC_010582.1 116717 117619 D hypothetical protein 116717..117619 Streptococcus pneumoniae CGSP14 6217369 YP_001834835.1 CDS SPCG_0118 NC_010582.1 117642 118007 D hypothetical protein 117642..118007 Streptococcus pneumoniae CGSP14 6217167 YP_001834836.1 CDS SPCG_0119 NC_010582.1 117974 118732 D hypothetical protein 117974..118732 Streptococcus pneumoniae CGSP14 6217249 YP_001834837.1 CDS pspA NC_010582.1 120255 122084 D surface protein A 120255..122084 Streptococcus pneumoniae CGSP14 6217682 YP_001834838.1 CDS mnmA NC_010582.1 122431 123606 D catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 122431..123606 Streptococcus pneumoniae CGSP14 6218108 YP_001834839.1 CDS SPCG_0122 NC_010582.1 123720 124202 D mutT/nudix family protein 123720..124202 Streptococcus pneumoniae CGSP14 6216519 YP_001834840.1 CDS gidA NC_010582.1 124212 126125 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 124212..126125 Streptococcus pneumoniae CGSP14 6217926 YP_001834841.1 CDS SPCG_0124 NC_010582.1 126478 128157 R metallo-beta-lactamase superfamily protein complement(126478..128157) Streptococcus pneumoniae CGSP14 6218372 YP_001834842.1 CDS SPCG_0125 NC_010582.1 128159 128392 R hypothetical protein complement(128159..128392) Streptococcus pneumoniae CGSP14 6216866 YP_001834843.1 CDS SPCG_0126 NC_010582.1 128672 128779 D hypothetical protein 128672..128779 Streptococcus pneumoniae CGSP14 6218232 YP_001834844.1 CDS SPCG_0127 NC_010582.1 128802 128963 R competence-induced protein Ccs1, truncated complement(128802..128963) Streptococcus pneumoniae CGSP14 6218092 YP_001834845.1 CDS SPCG_0128 NC_010582.1 129210 129362 R hypothetical protein complement(129210..129362) Streptococcus pneumoniae CGSP14 6217827 YP_001834846.1 CDS SPCG_0129 NC_010582.1 129364 129549 R hypothetical protein complement(129364..129549) Streptococcus pneumoniae CGSP14 6217645 YP_001834847.1 CDS SPCG_0130 NC_010582.1 129727 130410 D hypothetical protein 129727..130410 Streptococcus pneumoniae CGSP14 6216557 YP_001834848.1 CDS rimI NC_010582.1 130407 130844 D ribosomal-protein-alanine acetyltransferase 130407..130844 Streptococcus pneumoniae CGSP14 6217942 YP_001834849.1 CDS gcp NC_010582.1 130834 131844 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 130834..131844 Streptococcus pneumoniae CGSP14 6218065 YP_001834850.1 CDS SPCG_0133 NC_010582.1 131884 132270 R degenerate transposase complement(131884..132270) Streptococcus pneumoniae CGSP14 6216794 YP_001834851.1 CDS SPCG_0134 NC_010582.1 132477 133325 R degenerate transposase complement(132477..133325) Streptococcus pneumoniae CGSP14 6218161 YP_001834852.1 CDS SPCG_0135 NC_010582.1 134450 135013 D hypothetical protein 134450..135013 Streptococcus pneumoniae CGSP14 6216733 YP_001834853.1 CDS epsG NC_010582.1 135141 135602 D glycosyl transferase family protein 135141..135602 Streptococcus pneumoniae CGSP14 6216838 YP_001834854.1 CDS SPCG_0137 NC_010582.1 135626 136579 D glycosyl transferase family protein 135626..136579 Streptococcus pneumoniae CGSP14 6218211 YP_001834855.1 CDS SPCG_0138 NC_010582.1 136589 138205 D ABC transporter ATP-binding protein 136589..138205 Streptococcus pneumoniae CGSP14 6217010 YP_001834856.1 CDS SPCG_0139 NC_010582.1 138129 139070 D hypothetical protein 138129..139070 Streptococcus pneumoniae CGSP14 6218120 YP_001834857.1 CDS SPCG_0140 NC_010582.1 139099 140637 D hypothetical protein 139099..140637 Streptococcus pneumoniae CGSP14 6217670 YP_001834858.1 CDS SPCG_0141 NC_010582.1 140643 141398 D hypothetical protein 140643..141398 Streptococcus pneumoniae CGSP14 6217043 YP_001834859.1 CDS ugd NC_010582.1 141411 142583 D UDP-glucose dehydrogenase 141411..142583 Streptococcus pneumoniae CGSP14 6218369 YP_001834860.1 CDS mutR NC_010582.1 142954 143841 D transcriptional regulator 142954..143841 Streptococcus pneumoniae CGSP14 6217542 YP_001834861.1 CDS SPCG_0144 NC_010582.1 144111 144236 D bacteriocin 144111..144236 Streptococcus pneumoniae CGSP14 6217298 YP_001834862.1 CDS SPCG_0145 NC_010582.1 144296 147211 D lantibiotic biosynthesis protein 144296..147211 Streptococcus pneumoniae CGSP14 6218217 YP_001834863.1 CDS SPCG_0146 NC_010582.1 147195 148472 D lantibiotic biosynthesis protein 147195..148472 Streptococcus pneumoniae CGSP14 6218205 YP_001834864.1 CDS SPCG_0147 NC_010582.1 148501 149757 D lantibiotic efflux protein 148501..149757 Streptococcus pneumoniae CGSP14 6217420 YP_001834865.1 CDS SPCG_0148 NC_010582.1 149836 150513 D hypothetical protein 149836..150513 Streptococcus pneumoniae CGSP14 6218050 YP_001834866.1 CDS SPCG_0149 NC_010582.1 150525 151190 D hypothetical protein 150525..151190 Streptococcus pneumoniae CGSP14 6216971 YP_001834867.1 CDS SPCG_0150 NC_010582.1 151259 152488 D hypothetical protein 151259..152488 Streptococcus pneumoniae CGSP14 6216893 YP_001834868.1 CDS SPCG_0151 NC_010582.1 152943 153557 D hypothetical protein 152943..153557 Streptococcus pneumoniae CGSP14 6217407 YP_001834869.1 CDS SPCG_0152 NC_010582.1 153661 154491 D ABC transporter substrate-binding protein 153661..154491 Streptococcus pneumoniae CGSP14 6216483 YP_001834870.1 CDS SPCG_0153 NC_010582.1 154645 155499 D lipoprotein 154645..155499 Streptococcus pneumoniae CGSP14 6218225 YP_001834871.1 CDS SPCG_0154 NC_010582.1 155596 156969 D hypothetical protein 155596..156969 Streptococcus pneumoniae CGSP14 6218260 YP_001834872.1 CDS SPCG_0155 NC_010582.1 156962 158023 D ABC transporter ATP-binding protein 156962..158023 Streptococcus pneumoniae CGSP14 6216484 YP_001834873.1 CDS SPCG_0156 NC_010582.1 158025 158717 D ABC transporter permease 158025..158717 Streptococcus pneumoniae CGSP14 6217952 YP_001834874.1 CDS SPCG_0157 NC_010582.1 158833 159606 D transcriptional activator Rgg/GadR/MutR family protein 158833..159606 Streptococcus pneumoniae CGSP14 6216497 YP_001834875.1 CDS SPCG_0158 NC_010582.1 159788 159907 D hypothetical protein 159788..159907 Streptococcus pneumoniae CGSP14 6217254 YP_001834876.1 CDS SPCG_0159 NC_010582.1 159930 160244 D hypothetical protein 159930..160244 Streptococcus pneumoniae CGSP14 6216498 YP_001834877.1 CDS SPCG_0160 NC_010582.1 160260 160646 D hypothetical protein 160260..160646 Streptococcus pneumoniae CGSP14 6217223 YP_001834878.1 CDS SPCG_0161 NC_010582.1 160675 162060 D hypothetical protein 160675..162060 Streptococcus pneumoniae CGSP14 6217925 YP_001834879.1 CDS SPCG_0162 NC_010582.1 162238 163443 D Tn916, transcriptional regulator 162238..163443 Streptococcus pneumoniae CGSP14 6217565 YP_001834880.1 CDS SPCG_0163 NC_010582.1 163486 163707 D hypothetical protein 163486..163707 Streptococcus pneumoniae CGSP14 6217684 YP_001834881.1 CDS SPCG_0164 NC_010582.1 163824 164321 D hypothetical protein 163824..164321 Streptococcus pneumoniae CGSP14 6216474 YP_001834882.1 CDS SPCG_0165 NC_010582.1 164296 164802 D hypothetical protein 164296..164802 Streptococcus pneumoniae CGSP14 6216528 YP_001834883.1 CDS SPCG_0166 NC_010582.1 164735 167233 D hypothetical protein 164735..167233 Streptococcus pneumoniae CGSP14 6217931 YP_001834884.1 CDS SPCG_0167 NC_010582.1 167236 169413 D hypothetical protein 167236..169413 Streptococcus pneumoniae CGSP14 6216624 YP_001834885.1 CDS SPCG_0168 NC_010582.1 169410 170411 D hypothetical protein 169410..170411 Streptococcus pneumoniae CGSP14 6217606 YP_001834886.1 CDS SPCG_0169 NC_010582.1 170408 171343 D hypothetical protein 170408..171343 Streptococcus pneumoniae CGSP14 6216655 YP_001834887.1 CDS SPCG_0170 NC_010582.1 171618 171704 D regulates the transcription of tet(M) by attenuation; tetracycline resistance determinant leader peptide 171618..171704 Streptococcus pneumoniae CGSP14 6218265 YP_001834888.1 CDS SPCG_0171 NC_010582.1 171705 173639 D tetracycline resistance protein TetM 171705..173639 Streptococcus pneumoniae CGSP14 6216664 YP_001834889.1 CDS SPCG_0172 NC_010582.1 174564 175301 D rRNA methylase 174564..175301 Streptococcus pneumoniae CGSP14 6217896 YP_001834890.1 CDS SPCG_0173 NC_010582.1 175656 176210 D resolvase 175656..176210 Streptococcus pneumoniae CGSP14 6216916 YP_001834891.1 CDS SPCG_0174 NC_010582.1 176214 179132 D transposase 176214..179132 Streptococcus pneumoniae CGSP14 6218176 YP_001834892.1 CDS SPCG_0175 NC_010582.1 179188 179427 R hypothetical protein complement(179188..179427) Streptococcus pneumoniae CGSP14 6217621 YP_001834893.1 CDS SPCG_0176 NC_010582.1 179923 180354 D hypothetical protein 179923..180354 Streptococcus pneumoniae CGSP14 6217172 YP_001834894.1 CDS SPCG_0177 NC_010582.1 180351 180581 D hypothetical protein 180351..180581 Streptococcus pneumoniae CGSP14 6216701 YP_001834895.1 CDS SPCG_0178 NC_010582.1 181042 181245 D hypothetical protein 181042..181245 Streptococcus pneumoniae CGSP14 6218246 YP_001834896.1 CDS SPCG_0179 NC_010582.1 181327 182544 D hypothetical protein 181327..182544 Streptococcus pneumoniae CGSP14 6216887 YP_001834897.1 CDS SPCG_0180 NC_010582.1 182961 184277 D hypothetical protein 182961..184277 Streptococcus pneumoniae CGSP14 6218511 YP_001834898.1 CDS SPCG_0181 NC_010582.1 184315 184518 D hypothetical protein 184315..184518 Streptococcus pneumoniae CGSP14 6217698 YP_001834899.1 CDS SPCG_0182 NC_010582.1 184713 185375 R hypothetical protein complement(184713..185375) Streptococcus pneumoniae CGSP14 6216678 YP_001834900.1 CDS SPCG_0183 NC_010582.1 185632 186213 D hypothetical protein 185632..186213 Streptococcus pneumoniae CGSP14 6216973 YP_001834901.1 CDS SPCG_0184 NC_010582.1 186159 186761 D has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF; flavoprotein NrdI 186159..186761 Streptococcus pneumoniae CGSP14 6218326 YP_001834902.1 CDS SPCG_0185 NC_010582.1 187054 188361 R hypothetical protein complement(187054..188361) Streptococcus pneumoniae CGSP14 6216769 YP_001834903.1 CDS SPCG_0186 NC_010582.1 188626 189084 R hypothetical protein complement(188626..189084) Streptococcus pneumoniae CGSP14 6216978 YP_001834904.1 CDS SPCG_0187 NC_010582.1 189081 189602 R hypothetical protein complement(189081..189602) Streptococcus pneumoniae CGSP14 6216633 YP_001834905.1 CDS mutL NC_010582.1 189877 191826 D This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex; DNA mismatch repair protein 189877..191826 Streptococcus pneumoniae CGSP14 6218250 YP_001834906.1 CDS ribH NC_010582.1 192151 192618 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(192151..192618) Streptococcus pneumoniae CGSP14 6217429 YP_001834907.1 CDS ribA NC_010582.1 192619 193854 R 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(192619..193854) Streptococcus pneumoniae CGSP14 6217181 YP_001834908.1 CDS ribC NC_010582.1 193844 194479 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(193844..194479) Streptococcus pneumoniae CGSP14 6216914 YP_001834909.1 CDS ribD NC_010582.1 194464 195564 R riboflavin biosynthesis protein RibD complement(194464..195564) Streptococcus pneumoniae CGSP14 6217884 YP_001834910.1 CDS ruvA NC_010582.1 195970 196563 D plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 195970..196563 Streptococcus pneumoniae CGSP14 6216651 YP_001834911.1 CDS SPCG_0194 NC_010582.1 196219 196776 R hypothetical protein complement(196219..196776) Streptococcus pneumoniae CGSP14 6217953 YP_001834912.1 CDS tag NC_010582.1 196573 197136 D DNA-3-methyladenine glycosylase I 196573..197136 Streptococcus pneumoniae CGSP14 6218185 YP_001834913.1 CDS SPCG_0196 NC_010582.1 197133 197810 D hypothetical protein 197133..197810 Streptococcus pneumoniae CGSP14 6216995 YP_001834914.1 CDS SPCG_0197 NC_010582.1 197965 198996 R mccC family protein complement(197965..198996) Streptococcus pneumoniae CGSP14 6216767 YP_001834915.1 CDS SPCG_0198 NC_010582.1 199184 199279 R hypothetical protein complement(199184..199279) Streptococcus pneumoniae CGSP14 6218401 YP_001834916.1 CDS SPCG_0199 NC_010582.1 199251 199955 R hypothetical protein complement(199251..199955) Streptococcus pneumoniae CGSP14 6217849 YP_001834917.1 CDS SPCG_0200 NC_010582.1 199946 200890 R magnesium transporter CorA family protein complement(199946..200890) Streptococcus pneumoniae CGSP14 6217007 YP_001834918.1 CDS uvrA NC_010582.1 200989 203853 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate; excinuclease ABC subunit A 200989..203853 Streptococcus pneumoniae CGSP14 6218209 YP_001834919.1 CDS pepP NC_010582.1 203846 204907 D peptidase M24 family protein 203846..204907 Streptococcus pneumoniae CGSP14 6217045 YP_001834920.1 CDS spxA NC_010582.1 205039 205437 D the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx 205039..205437 Streptococcus pneumoniae CGSP14 6217294 YP_001834921.1 CDS SPCG_0204 NC_010582.1 205503 206072 D hypothetical protein 205503..206072 Streptococcus pneumoniae CGSP14 6217365 YP_001834922.1 CDS SPCG_0205 NC_010582.1 206159 206425 D hypothetical protein 206159..206425 Streptococcus pneumoniae CGSP14 6217026 YP_001834923.1 CDS SPCG_0206 NC_010582.1 206429 206848 D similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function; Holliday junction resolvase-like protein 206429..206848 Streptococcus pneumoniae CGSP14 6218464 YP_001834924.1 CDS SPCG_0207 NC_010582.1 206864 207169 D hypothetical protein 206864..207169 Streptococcus pneumoniae CGSP14 6218276 YP_001834925.1 CDS folC NC_010582.1 207471 208727 D dihydrofolate synthetase 207471..208727 Streptococcus pneumoniae CGSP14 6217331 YP_001834926.1 CDS SPCG_0209 NC_010582.1 208724 209269 D hypothetical protein 208724..209269 Streptococcus pneumoniae CGSP14 6217044 YP_001834927.1 CDS cls NC_010582.1 209415 210947 D cardiolipin synthetase 209415..210947 Streptococcus pneumoniae CGSP14 6217079 YP_001834928.1 CDS SPCG_0211 NC_010582.1 211187 212743 D competence-induced protein Ccs4 211187..212743 Streptococcus pneumoniae CGSP14 6218488 YP_001834929.1 CDS SPCG_0212 NC_010582.1 212857 215070 D Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; anaerobic ribonucleoside triphosphate reductase 212857..215070 Streptococcus pneumoniae CGSP14 6216881 YP_001834930.1 CDS SPCG_0213 NC_010582.1 215082 215222 D hypothetical protein 215082..215222 Streptococcus pneumoniae CGSP14 6217918 YP_001834931.1 CDS SPCG_0214 NC_010582.1 215266 215772 D acetyltransferase 215266..215772 Streptococcus pneumoniae CGSP14 6216520 YP_001834932.1 CDS nrdD NC_010582.1 215765 216355 D anaerobic ribonucleoside-triphosphate reductase activating protein 215765..216355 Streptococcus pneumoniae CGSP14 6216965 YP_001834933.1 CDS SPCG_0216 NC_010582.1 216352 216969 D hypothetical protein 216352..216969 Streptococcus pneumoniae CGSP14 6217324 YP_001834934.1 CDS rpsJ NC_010582.1 217236 217544 D NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 217236..217544 Streptococcus pneumoniae CGSP14 6217037 YP_001834935.1 CDS rplC NC_010582.1 217760 218386 D binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 217760..218386 Streptococcus pneumoniae CGSP14 6218580 YP_001834936.1 CDS rplD NC_010582.1 218411 219034 D L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 218411..219034 Streptococcus pneumoniae CGSP14 6216607 YP_001834937.1 CDS rplW NC_010582.1 219034 219330 D binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 219034..219330 Streptococcus pneumoniae CGSP14 6217095 YP_001834938.1 CDS rplB NC_010582.1 219348 220181 D one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 219348..220181 Streptococcus pneumoniae CGSP14 6217222 YP_001834939.1 CDS rpsS NC_010582.1 220273 220554 D protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 220273..220554 Streptococcus pneumoniae CGSP14 6217395 YP_001834940.1 CDS rplV NC_010582.1 220566 220910 D binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 220566..220910 Streptococcus pneumoniae CGSP14 6216643 YP_001834941.1 CDS rpsC NC_010582.1 220923 221576 D forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 220923..221576 Streptococcus pneumoniae CGSP14 6217648 YP_001834942.1 CDS rplP NC_010582.1 221580 221993 D located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 221580..221993 Streptococcus pneumoniae CGSP14 6217644 YP_001834943.1 CDS rpmC NC_010582.1 222003 222209 D one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 222003..222209 Streptococcus pneumoniae CGSP14 6217636 YP_001834944.1 CDS rpsQ NC_010582.1 222234 222494 D primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 222234..222494 Streptococcus pneumoniae CGSP14 6217629 YP_001834945.1 CDS rplN NC_010582.1 222520 222888 D binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 222520..222888 Streptococcus pneumoniae CGSP14 6217622 YP_001834946.1 CDS rplX NC_010582.1 222966 223271 D assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 222966..223271 Streptococcus pneumoniae CGSP14 6217611 YP_001834947.1 CDS rplE NC_010582.1 223295 223837 D part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 223295..223837 Streptococcus pneumoniae CGSP14 6217488 YP_001834948.1 CDS rpsN NC_010582.1 223855 224124 D located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif; 30S ribosomal protein S14 223855..224124 Streptococcus pneumoniae CGSP14 6218565 YP_001834949.1 CDS rpsH NC_010582.1 224338 224736 D binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 224338..224736 Streptococcus pneumoniae CGSP14 6217591 YP_001834950.1 CDS rplF NC_010582.1 224928 225464 D ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 224928..225464 Streptococcus pneumoniae CGSP14 6217575 YP_001834951.1 CDS rplR NC_010582.1 225509 225904 D binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 225509..225904 Streptococcus pneumoniae CGSP14 6217231 YP_001834952.1 CDS rpsE NC_010582.1 225922 226416 D located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 225922..226416 Streptococcus pneumoniae CGSP14 6216976 YP_001834953.1 CDS rpmD NC_010582.1 226388 226612 D L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7; 50S ribosomal protein L30 226388..226612 Streptococcus pneumoniae CGSP14 6217561 YP_001834954.1 CDS rplO NC_010582.1 226757 227197 D late assembly protein; 50S ribosomal protein L15 226757..227197 Streptococcus pneumoniae CGSP14 6217552 YP_001834955.1 CDS secY NC_010582.1 227210 228520 D forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 227210..228520 Streptococcus pneumoniae CGSP14 6217536 YP_001834956.1 CDS adk NC_010582.1 228671 229309 D essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP; adenylate kinase 228671..229309 Streptococcus pneumoniae CGSP14 6217518 YP_001834957.1 CDS infA NC_010582.1 229372 229644 D stimulates the activities of the other two initiation factors, IF-2 and IF-3; translation initiation factor IF-1 229372..229644 Streptococcus pneumoniae CGSP14 6217512 YP_001834958.1 CDS rpsM NC_010582.1 229803 230168 D located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 229803..230168 Streptococcus pneumoniae CGSP14 6217505 YP_001834959.1 CDS rpsK NC_010582.1 230186 230569 D located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 230186..230569 Streptococcus pneumoniae CGSP14 6217503 YP_001834960.1 CDS rpoA NC_010582.1 230612 231547 D catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 230612..231547 Streptococcus pneumoniae CGSP14 6217492 YP_001834961.1 CDS rplQ NC_010582.1 231559 231945 D is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 231559..231945 Streptococcus pneumoniae CGSP14 6217491 YP_001834962.1 CDS SPCG_0245 NC_010582.1 232117 232476 D ACT domain-containing protein; hypothetical protein 232117..232476 Streptococcus pneumoniae CGSP14 6217122 YP_001834963.1 CDS SPCG_0246 NC_010582.1 232523 233824 D hypothetical protein 232523..233824 Streptococcus pneumoniae CGSP14 6218519 YP_001834964.1 CDS gpmB NC_010582.1 234011 234760 D phosphoglycerate mutase family protein 234011..234760 Streptococcus pneumoniae CGSP14 6217347 YP_001834965.1 CDS SPCG_0248 NC_010582.1 234863 235897 R iron ABC transporter permease complement(234863..235897) Streptococcus pneumoniae CGSP14 6217463 YP_001834966.1 CDS SPCG_0250 NC_010582.1 235882 236418 R iron ABC transporter permease complement(235882..236418) Streptococcus pneumoniae CGSP14 6217442 YP_001834967.1 CDS SPCG_0249 NC_010582.1 236393 236485 R hypothetical protein complement(236393..236485) Streptococcus pneumoniae CGSP14 6217693 YP_001834968.1 CDS SPCG_0251 NC_010582.1 236462 236560 D hypothetical protein 236462..236560 Streptococcus pneumoniae CGSP14 6217419 YP_001834969.1 CDS SPCG_0252 NC_010582.1 236498 236902 R hypothetical protein complement(236498..236902) Streptococcus pneumoniae CGSP14 6217426 YP_001834970.1 CDS SPCG_0253 NC_010582.1 236930 237526 R hypothetical protein complement(236930..237526) Streptococcus pneumoniae CGSP14 6217414 YP_001834971.1 CDS SPCG_0254 NC_010582.1 237601 237969 R hypothetical protein complement(237601..237969) Streptococcus pneumoniae CGSP14 6217399 YP_001834972.1 CDS SPCG_0255 NC_010582.1 238114 238707 R hypothetical protein complement(238114..238707) Streptococcus pneumoniae CGSP14 6217390 YP_001834973.1 CDS pflE NC_010582.1 239211 239987 R pyruvate formate-lyase-activating enzyme complement(239211..239987) Streptococcus pneumoniae CGSP14 6217387 YP_001834974.1 CDS deoR NC_010582.1 240061 240855 D DeoR family transcriptional regulator 240061..240855 Streptococcus pneumoniae CGSP14 6217764 YP_001834975.1 CDS SPCG_0258 NC_010582.1 240868 241848 D transcriptional regulator 240868..241848 Streptococcus pneumoniae CGSP14 6217450 YP_001834976.1 CDS SPCG_0259 NC_010582.1 242043 242363 D PTS system transporter subunit IIA 242043..242363 Streptococcus pneumoniae CGSP14 6217216 YP_001834977.1 CDS SPCG_0260 NC_010582.1 242409 242717 D PTS system transporter subunit IIB 242409..242717 Streptococcus pneumoniae CGSP14 6217366 YP_001834978.1 CDS SPCG_0261 NC_010582.1 242710 244032 D PTS system transporter subunit IIC 242710..244032 Streptococcus pneumoniae CGSP14 6217362 YP_001834979.1 CDS pflF NC_010582.1 244174 246621 D formate acetyltransferase 244174..246621 Streptococcus pneumoniae CGSP14 6217358 YP_001834980.1 CDS talC NC_010582.1 246640 247308 D similar to transaldolase from Escherichia coli; many organisms have multiple copies; fructose-6-phosphate aldolase 246640..247308 Streptococcus pneumoniae CGSP14 6217354 YP_001834981.1 CDS gldA NC_010582.1 247326 248414 D forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone; glycerol dehydrogenase 247326..248414 Streptococcus pneumoniae CGSP14 6217349 YP_001834982.1 CDS leuS NC_010582.1 248869 251370 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 248869..251370 Streptococcus pneumoniae CGSP14 6217345 YP_001834983.1 CDS SPCG_0266 NC_010582.1 251565 252260 D acetyltransferase 251565..252260 Streptococcus pneumoniae CGSP14 6217344 YP_001834984.1 CDS SPCG_0267 NC_010582.1 252272 252688 D acetyltransferase 252272..252688 Streptococcus pneumoniae CGSP14 6217337 YP_001834985.1 CDS SPCG_0268 NC_010582.1 253503 253595 R hypothetical protein complement(253503..253595) Streptococcus pneumoniae CGSP14 6217332 YP_001834986.1 CDS ruvB NC_010582.1 253729 254727 D promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 253729..254727 Streptococcus pneumoniae CGSP14 6217780 YP_001834987.1 CDS SPCG_0270 NC_010582.1 254693 255280 D hypothetical protein 254693..255280 Streptococcus pneumoniae CGSP14 6217328 YP_001834988.1 CDS uppS NC_010582.1 255493 256269 D catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate; undecaprenyl pyrophosphate synthase 255493..256269 Streptococcus pneumoniae CGSP14 6217375 YP_001834989.1 CDS cdsA NC_010582.1 256278 257081 D phosphatidate cytidylyltransferase 256278..257081 Streptococcus pneumoniae CGSP14 6217752 YP_001834990.1 CDS eep NC_010582.1 257103 258362 D eep protein 257103..258362 Streptococcus pneumoniae CGSP14 6216798 YP_001834991.1 CDS proS NC_010582.1 258375 260228 D catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 258375..260228 Streptococcus pneumoniae CGSP14 6218199 YP_001834992.1 CDS SPCG_0275 NC_010582.1 260327 261706 D glycosyl hydrolase family protein 260327..261706 Streptococcus pneumoniae CGSP14 6217309 YP_001834993.1 CDS glmS NC_010582.1 261899 263707 D Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source; glucosamine--fructose-6-phosphate aminotransferase 261899..263707 Streptococcus pneumoniae CGSP14 6217306 YP_001834994.1 CDS SPCG_0277 NC_010582.1 263826 264875 D oxidoreductase 263826..264875 Streptococcus pneumoniae CGSP14 6217301 YP_001834995.1 CDS SPCG_0278 NC_010582.1 264975 268772 R alkaline amylopullulanase complement(264975..268772) Streptococcus pneumoniae CGSP14 6217283 YP_001834996.1 CDS SPCG_0279 NC_010582.1 268849 270405 D IS1380-Spn1 transposase 268849..270405 Streptococcus pneumoniae CGSP14 6217321 YP_001834997.1 CDS SPCG_0280 NC_010582.1 270667 270762 D hypothetical protein 270667..270762 Streptococcus pneumoniae CGSP14 6217268 YP_001834998.1 CDS SPCG_0281 NC_010582.1 270818 270910 D hypothetical protein 270818..270910 Streptococcus pneumoniae CGSP14 6217266 YP_001834999.1 CDS rpsL NC_010582.1 270897 271310 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 270897..271310 Streptococcus pneumoniae CGSP14 6217483 YP_001835000.1 CDS rpsG NC_010582.1 271330 271800 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 271330..271800 Streptococcus pneumoniae CGSP14 6216968 YP_001835001.1 CDS fusA NC_010582.1 272225 274306 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 272225..274306 Streptococcus pneumoniae CGSP14 6216961 YP_001835002.1 CDS polC NC_010582.1 274410 278801 D catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; required for leading strand synthesis; PolC exhibits 3' to 5' exonuclease activity; DNA polymerase III PolC 274410..278801 Streptococcus pneumoniae CGSP14 6217001 YP_001835003.1 CDS SPCG_0286 NC_010582.1 278903 279166 D hypothetical protein 278903..279166 Streptococcus pneumoniae CGSP14 6216953 YP_001835004.1 CDS SPCG_0287 NC_010582.1 279159 279437 D hypothetical protein 279159..279437 Streptococcus pneumoniae CGSP14 6216951 YP_001835005.1 CDS SPCG_0288 NC_010582.1 279458 279610 D hypothetical protein 279458..279610 Streptococcus pneumoniae CGSP14 6216937 YP_001835006.1 CDS pepS NC_010582.1 279632 280873 D aminopeptidase PepS 279632..280873 Streptococcus pneumoniae CGSP14 6217073 YP_001835007.1 CDS SPCG_0290 NC_010582.1 280883 281113 D hypothetical protein 280883..281113 Streptococcus pneumoniae CGSP14 6216927 YP_001835008.1 CDS rsuA NC_010582.1 281369 282091 D ribosomal small subunit pseudouridine synthase A 281369..282091 Streptococcus pneumoniae CGSP14 6217046 YP_001835009.1 CDS pepC NC_010582.1 282308 283642 D aminopeptidase C 282308..283642 Streptococcus pneumoniae CGSP14 6216913 YP_001835010.1 CDS manN NC_010582.1 283698 284609 R PTS system mannose-specific transporter subunit IID complement(283698..284609) Streptococcus pneumoniae CGSP14 6216378 YP_001835011.1 CDS manM NC_010582.1 284633 285436 R PTS system mannose-specific transporter subunit IIC complement(284633..285436) Streptococcus pneumoniae CGSP14 6216907 YP_001835012.1 CDS manL NC_010582.1 285464 286462 R PTS system mannose-specific transporter subunit IIAB complement(285464..286462) Streptococcus pneumoniae CGSP14 6216905 YP_001835013.1 CDS SPCG_0296 NC_010582.1 286862 288469 R IS1380-Spn1 transposase complement(286862..288469) Streptococcus pneumoniae CGSP14 6217135 YP_001835014.1 CDS adhP NC_010582.1 288396 289415 R similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs; alcohol dehydrogenase complement(288396..289415) Streptococcus pneumoniae CGSP14 6216867 YP_001835015.1 CDS SPCG_0298 NC_010582.1 289524 289670 R hypothetical protein complement(289524..289670) Streptococcus pneumoniae CGSP14 6216597 YP_001835016.1 CDS SPCG_0299 NC_010582.1 289754 290566 R Cof family protein complement(289754..290566) Streptococcus pneumoniae CGSP14 6217163 YP_001835017.1 CDS SPCG_0300 NC_010582.1 290702 292174 D xanthine/uracil permease family protein 290702..292174 Streptococcus pneumoniae CGSP14 6216457 YP_001835018.1 CDS SPCG_0301 NC_010582.1 292224 292934 D hypothetical protein 292224..292934 Streptococcus pneumoniae CGSP14 6217250 YP_001835019.1 CDS sulA NC_010582.1 293028 294008 D dihydropteroate synthase 293028..294008 Streptococcus pneumoniae CGSP14 6217034 YP_001835020.1 CDS sulB NC_010582.1 294010 295332 D dihydrofolate synthetase 294010..295332 Streptococcus pneumoniae CGSP14 6216889 YP_001835021.1 CDS folE NC_010582.1 295313 295867 D involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; GTP cyclohydrolase I 295313..295867 Streptococcus pneumoniae CGSP14 6217486 YP_001835022.1 CDS sulD NC_010582.1 295910 296722 D bifunctional folate synthesis protein 295910..296722 Streptococcus pneumoniae CGSP14 6216327 YP_001835023.1 CDS SPCG_0306 NC_010582.1 296767 297138 R hypothetical protein complement(296767..297138) Streptococcus pneumoniae CGSP14 6216811 YP_001835024.1 CDS SPCG_0307 NC_010582.1 297128 297232 R hypothetical protein complement(297128..297232) Streptococcus pneumoniae CGSP14 6217159 YP_001835025.1 CDS rplM NC_010582.1 297441 297887 D in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 297441..297887 Streptococcus pneumoniae CGSP14 6216807 YP_001835026.1 CDS rpsI NC_010582.1 297907 298299 D forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 297907..298299 Streptococcus pneumoniae CGSP14 6216801 YP_001835027.1 CDS SPCG_0310 NC_010582.1 298767 298937 D hypothetical protein 298767..298937 Streptococcus pneumoniae CGSP14 6217313 YP_001835028.1 CDS SPCG_0311 NC_010582.1 299013 299351 D hypothetical protein 299013..299351 Streptococcus pneumoniae CGSP14 6216788 YP_001835029.1 CDS celA NC_010582.1 299499 300977 D converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism; 6-phospho-beta-glucosidase 299499..300977 Streptococcus pneumoniae CGSP14 6216785 YP_001835030.1 CDS SPCG_0313 NC_010582.1 301029 301268 D hypothetical protein 301029..301268 Streptococcus pneumoniae CGSP14 6216783 YP_001835031.1 CDS celB NC_010582.1 301371 301712 D required for cellobiose uptake and metabolism; PTS system cellobiose transporter subunit IIB 301371..301712 Streptococcus pneumoniae CGSP14 6216781 YP_001835032.1 CDS SPCG_0315 NC_010582.1 301830 303809 D PTS system transporter subunit IIB 301830..303809 Streptococcus pneumoniae CGSP14 6216779 YP_001835033.1 CDS celC NC_010582.1 303819 304133 D required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIA component 303819..304133 Streptococcus pneumoniae CGSP14 6216777 YP_001835034.1 CDS SPCG_0317 NC_010582.1 304164 304670 D hypothetical protein 304164..304670 Streptococcus pneumoniae CGSP14 6216775 YP_001835035.1 CDS celD NC_010582.1 304750 306096 D required for cellobiose uptake and metabolism; cellobiose phosphotransferase system IIC component 304750..306096 Streptococcus pneumoniae CGSP14 6216764 YP_001835036.1 CDS SPCG_0319 NC_010582.1 306477 306653 D hypothetical protein 306477..306653 Streptococcus pneumoniae CGSP14 6216618 YP_001835037.1 CDS SPCG_0320 NC_010582.1 307055 309268 D glycosyl hydrolase family protein 307055..309268 Streptococcus pneumoniae CGSP14 6217198 YP_001835038.1 CDS basA NC_010582.1 309490 309966 R glutathione peroxidase complement(309490..309966) Streptococcus pneumoniae CGSP14 6217398 YP_001835039.1 CDS SPCG_0322 NC_010582.1 310156 313392 D hyaluronidase 310156..313392 Streptococcus pneumoniae CGSP14 6216762 YP_001835040.1 CDS kdgA NC_010582.1 314536 315165 R catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; keto-hydroxyglutarate-aldolase/keto-deoxy- phosphogluconate aldolase complement(314536..315165) Streptococcus pneumoniae CGSP14 6216753 YP_001835041.1 CDS SPCG_0324 NC_010582.1 315175 316176 R carbohydrate kinase complement(315175..316176) Streptococcus pneumoniae CGSP14 6216745 YP_001835042.1 CDS SPCG_0325 NC_010582.1 316207 316848 R hypothetical protein complement(316207..316848) Streptococcus pneumoniae CGSP14 6216739 YP_001835043.1 CDS gno NC_010582.1 316867 317682 R Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate; gluconate 5-dehydrogenase complement(316867..317682) Streptococcus pneumoniae CGSP14 6218019 YP_001835044.1 CDS SPCG_0327 NC_010582.1 317954 318388 D PTS system transporter subunit IIA 317954..318388 Streptococcus pneumoniae CGSP14 6216817 YP_001835045.1 CDS SPCG_0328 NC_010582.1 318400 319590 D glucuronyl hydrolase 318400..319590 Streptococcus pneumoniae CGSP14 6217199 YP_001835046.1 CDS SPCG_0329 NC_010582.1 319601 320092 D PTS system transporter subunit IIB 319601..320092 Streptococcus pneumoniae CGSP14 6217196 YP_001835047.1 CDS SPCG_0330 NC_010582.1 320107 320886 D PTS system transporter subunit IIC 320107..320886 Streptococcus pneumoniae CGSP14 6217041 YP_001835048.1 CDS SPCG_0331 NC_010582.1 320873 321691 D PTS system transporter subunit IID 320873..321691 Streptococcus pneumoniae CGSP14 6216727 YP_001835049.1 CDS SPCG_0332 NC_010582.1 321691 321984 D preprotein translocase subunit YajC 321691..321984 Streptococcus pneumoniae CGSP14 6216992 YP_001835050.1 CDS SPCG_0333 NC_010582.1 322006 323907 D hypothetical protein 322006..323907 Streptococcus pneumoniae CGSP14 6216909 YP_001835051.1 CDS regR NC_010582.1 323901 324968 D sugar binding transcriptional regulator RegR 323901..324968 Streptococcus pneumoniae CGSP14 6216376 YP_001835052.1 CDS SPCG_0335 NC_010582.1 325424 325666 R hypothetical protein complement(325424..325666) Streptococcus pneumoniae CGSP14 6216724 YP_001835053.1 CDS yorfE NC_010582.1 325682 325876 R transcriptional regulator complement(325682..325876) Streptococcus pneumoniae CGSP14 6216723 YP_001835054.1 CDS mraW NC_010582.1 326042 326992 D S-adenosyl-methyltransferase MraW 326042..326992 Streptococcus pneumoniae CGSP14 6216720 YP_001835055.1 CDS ftsL NC_010582.1 327004 327321 D cell division protein FtsL 327004..327321 Streptococcus pneumoniae CGSP14 6216717 YP_001835056.1 CDS pbp2X NC_010582.1 327325 329577 D penicillin-binding protein 2X 327325..329577 Streptococcus pneumoniae CGSP14 6216714 YP_001835057.1 CDS mraY NC_010582.1 329579 330559 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 329579..330559 Streptococcus pneumoniae CGSP14 6216713 YP_001835058.1 CDS SPCG_0341 NC_010582.1 330699 330887 D hypothetical protein 330699..330887 Streptococcus pneumoniae CGSP14 6216712 YP_001835059.1 CDS clpL NC_010582.1 331168 333273 D ATP-dependent Clp protease, ATP-binding subunit 331168..333273 Streptococcus pneumoniae CGSP14 6216699 YP_001835060.1 CDS luxS NC_010582.1 334126 334608 R catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2; S-ribosylhomocysteinase complement(334126..334608) Streptococcus pneumoniae CGSP14 6217141 YP_001835061.1 CDS SPCG_0344 NC_010582.1 334703 336187 R hypothetical protein complement(334703..336187) Streptococcus pneumoniae CGSP14 6216621 YP_001835062.1 CDS dexB NC_010582.1 336340 337947 D glucan 1,6-alpha-glucosidase 336340..337947 Streptococcus pneumoniae CGSP14 6216697 YP_001835063.1 CDS wzg NC_010582.1 339007 340461 D capsular polysaccharide biosynthesis protein Cps14A 339007..340461 Streptococcus pneumoniae CGSP14 6216691 YP_001835064.1 CDS wzh NC_010582.1 340463 341194 D capsular polysaccharide biosynthesis protein Cps14B 340463..341194 Streptococcus pneumoniae CGSP14 6216690 YP_001835065.1 CDS wzd NC_010582.1 341203 341895 D capsular polysaccharide biosynthesis protein Cps14C 341203..341895 Streptococcus pneumoniae CGSP14 6216642 YP_001835066.1 CDS wze NC_010582.1 341905 342588 D capsular polysaccharide biosynthesis protein Cps14D 341905..342588 Streptococcus pneumoniae CGSP14 6217227 YP_001835067.1 CDS wchA NC_010582.1 342604 343971 D glucosyl-1-phosphate transferase 342604..343971 Streptococcus pneumoniae CGSP14 6217768 YP_001835068.1 CDS wchJ NC_010582.1 343975 344424 D glycosyltransferase activity enhancer 343975..344424 Streptococcus pneumoniae CGSP14 6216682 YP_001835069.1 CDS wchK NC_010582.1 344424 344927 D ss-1,4-galactosyltransferase 344424..344927 Streptococcus pneumoniae CGSP14 6216681 YP_001835070.1 CDS wzy NC_010582.1 344917 346089 D polysaccharide polymerase 344917..346089 Streptococcus pneumoniae CGSP14 6216677 YP_001835071.1 CDS wchL NC_010582.1 346086 347105 D ss-1,3-N-acetylglucosaminyltransferase 346086..347105 Streptococcus pneumoniae CGSP14 6217171 YP_001835072.1 CDS wchM NC_010582.1 347075 348076 D ss-1,4-galactosyltransferase 347075..348076 Streptococcus pneumoniae CGSP14 6217132 YP_001835073.1 CDS wchN NC_010582.1 348144 349013 D capsular polysaccharide synthesis protein 348144..349013 Streptococcus pneumoniae CGSP14 6217352 YP_001835074.1 CDS wzx NC_010582.1 348997 350469 D transporter 348997..350469 Streptococcus pneumoniae CGSP14 6217097 YP_001835075.1 CDS SPCG_0358 NC_010582.1 350621 350713 D hypothetical protein 350621..350713 Streptococcus pneumoniae CGSP14 6217703 YP_001835076.1 CDS SPCG_0359 NC_010582.1 350730 351047 D hypothetical protein 350730..351047 Streptococcus pneumoniae CGSP14 6217229 YP_001835077.1 CDS lrp NC_010582.1 351407 353770 D surface anchored protein 351407..353770 Streptococcus pneumoniae CGSP14 6216940 YP_001835078.1 CDS SPCG_0361 NC_010582.1 353925 354452 R degenerate transposase complement(353925..354452) Streptococcus pneumoniae CGSP14 6216379 YP_001835079.1 CDS SPCG_0362 NC_010582.1 354733 355251 R degenerate transposase complement(354733..355251) Streptococcus pneumoniae CGSP14 6217863 YP_001835080.1 CDS aliA NC_010582.1 355487 357472 D oligopeptide ABC transporter oligopeptide-binding protein AliA 355487..357472 Streptococcus pneumoniae CGSP14 6216966 YP_001835081.1 CDS SPCG_0364 NC_010582.1 357773 363076 D cell wall surface anchor family protein 357773..363076 Streptococcus pneumoniae CGSP14 6217035 YP_001835082.1 CDS pbp1A NC_010582.1 363243 365402 R penicillin-binding protein 1A complement(363243..365402) Streptococcus pneumoniae CGSP14 6217308 YP_001835083.1 CDS recU NC_010582.1 365399 365995 R functions in homologous recombination, DNA repair, and chromosome segregation; binds preferentially to three- and four-stranded DNA intermediates; introduces specific nick sites in four-stranded DNA substrates; functions similarly to Escherichia coli RuvC; Holliday junction-specific endonuclease complement(365399..365995) Streptococcus pneumoniae CGSP14 6217825 YP_001835084.1 CDS SPCG_0367 NC_010582.1 365978 366589 D hypothetical protein 365978..366589 Streptococcus pneumoniae CGSP14 6217843 YP_001835085.1 CDS SPCG_0368 NC_010582.1 366647 367000 D hypothetical protein 366647..367000 Streptococcus pneumoniae CGSP14 6217109 YP_001835086.1 CDS SPCG_0369 NC_010582.1 367471 368643 D hypothetical protein 367471..368643 Streptococcus pneumoniae CGSP14 6217595 YP_001835087.1 CDS SPCG_0370 NC_010582.1 368656 370050 D hypothetical protein 368656..370050 Streptococcus pneumoniae CGSP14 6216693 YP_001835088.1 CDS gnd NC_010582.1 370105 371550 D catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate; 6-phosphogluconate dehydrogenase 370105..371550 Streptococcus pneumoniae CGSP14 6217714 YP_001835089.1 CDS csrR NC_010582.1 371562 372251 D DNA-binding response regulator 371562..372251 Streptococcus pneumoniae CGSP14 6216962 YP_001835090.1 CDS cbpJ NC_010582.1 372260 373348 D choline binding protein J 372260..373348 Streptococcus pneumoniae CGSP14 6217319 YP_001835091.1 CDS SPCG_0374 NC_010582.1 373466 374722 R hypothetical protein complement(373466..374722) Streptococcus pneumoniae CGSP14 6216760 YP_001835092.1 CDS SPCG_0375 NC_010582.1 374857 375327 R hypothetical protein complement(374857..375327) Streptococcus pneumoniae CGSP14 6217205 YP_001835093.1 CDS mvk NC_010582.1 376699 377577 D mevalonate kinase 376699..377577 Streptococcus pneumoniae CGSP14 6218251 YP_001835094.1 CDS mvd1 NC_010582.1 377559 378512 D diphosphomevalonate decarboxylase 377559..378512 Streptococcus pneumoniae CGSP14 6217412 YP_001835095.1 CDS mvaK2 NC_010582.1 378499 379506 D phosphomevalonate kinase 378499..379506 Streptococcus pneumoniae CGSP14 6218153 YP_001835096.1 CDS fni NC_010582.1 379490 380500 D catalyzes the isomerization of isopentenyl pyrophosphate to dimethylallyl diphosphate; isopentenyl pyrophosphate isomerase 379490..380500 Streptococcus pneumoniae CGSP14 6217477 YP_001835097.1 CDS SPCG_0380 NC_010582.1 380577 381275 D hypothetical protein 380577..381275 Streptococcus pneumoniae CGSP14 6218263 YP_001835098.1 CDS SPCG_0381 NC_010582.1 381272 382267 D sensor histidine kinase 381272..382267 Streptococcus pneumoniae CGSP14 6217705 YP_001835099.1 CDS SPCG_0382 NC_010582.1 382281 382913 D DNA-binding response regulator 382281..382913 Streptococcus pneumoniae CGSP14 6217108 YP_001835100.1 CDS SPCG_0383 NC_010582.1 382914 383156 D hypothetical protein 382914..383156 Streptococcus pneumoniae CGSP14 6217922 YP_001835101.1 CDS SPCG_0384 NC_010582.1 383138 383392 D DNA alkylation repair enzyme, truncation 383138..383392 Streptococcus pneumoniae CGSP14 6217638 YP_001835102.1 CDS SPCG_0385 NC_010582.1 383411 383683 D DNA alkylation repair enzyme, truncation 383411..383683 Streptococcus pneumoniae CGSP14 6218063 YP_001835103.1 CDS SPCG_0386 NC_010582.1 383833 384072 D hypothetical protein 383833..384072 Streptococcus pneumoniae CGSP14 6218296 YP_001835104.1 CDS cbpG NC_010582.1 384069 384974 D choline binding protein G 384069..384974 Streptococcus pneumoniae CGSP14 6217428 YP_001835105.1 CDS SPCG_0388 NC_010582.1 384993 385418 D hypothetical protein 384993..385418 Streptococcus pneumoniae CGSP14 6216467 YP_001835106.1 CDS SPCG_0389 NC_010582.1 385536 386015 D hypothetical protein 385536..386015 Streptococcus pneumoniae CGSP14 6218074 YP_001835107.1 CDS SPCG_0390 NC_010582.1 386143 386328 R degenerate transposase complement(386143..386328) Streptococcus pneumoniae CGSP14 6216684 YP_001835108.1 CDS SPCG_0391 NC_010582.1 386276 386506 R degenerate transposase complement(386276..386506) Streptococcus pneumoniae CGSP14 6216475 YP_001835109.1 CDS SPCG_0392 NC_010582.1 386568 386840 R degenerate transposase complement(386568..386840) Streptococcus pneumoniae CGSP14 6216446 YP_001835110.1 CDS SPCG_0393 NC_010582.1 387066 387341 R degenerate transposase complement(387066..387341) Streptococcus pneumoniae CGSP14 6217637 YP_001835111.1 CDS mtlA NC_010582.1 387487 389256 D PTS system mannitol-specific transporter subunit IIBC 387487..389256 Streptococcus pneumoniae CGSP14 6217017 YP_001835112.1 CDS SPCG_0395 NC_010582.1 389280 391235 D transcriptional regulator 389280..391235 Streptococcus pneumoniae CGSP14 6216606 YP_001835113.1 CDS mtlF NC_010582.1 391237 391674 D PTS system mannitol-specific transporter subunit IIA 391237..391674 Streptococcus pneumoniae CGSP14 6218241 YP_001835114.1 CDS mtlD NC_010582.1 391736 392872 D mannitol-1-phosphate 5-dehydrogenase 391736..392872 Streptococcus pneumoniae CGSP14 6217060 YP_001835115.1 CDS SPCG_0398 NC_010582.1 393088 393246 D hypothetical protein 393088..393246 Streptococcus pneumoniae CGSP14 6218146 YP_001835116.1 CDS tig NC_010582.1 393716 394999 D Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer; trigger factor 393716..394999 Streptococcus pneumoniae CGSP14 6216639 YP_001835117.1 CDS recD NC_010582.1 395047 397413 R helicase complement(395047..397413) Streptococcus pneumoniae CGSP14 6217954 YP_001835118.1 CDS spi NC_010582.1 397647 398261 R signal peptidase I complement(397647..398261) Streptococcus pneumoniae CGSP14 6216774 YP_001835119.1 CDS SPCG_0402 NC_010582.1 398273 399145 R An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids; ribonuclease HIII complement(398273..399145) Streptococcus pneumoniae CGSP14 6217850 YP_001835120.1 CDS SPCG_0403 NC_010582.1 399223 399534 D hypothetical protein 399223..399534 Streptococcus pneumoniae CGSP14 6218163 YP_001835121.1 CDS SPCG_0404 NC_010582.1 399531 400079 D hypothetical protein 399531..400079 Streptococcus pneumoniae CGSP14 6216654 YP_001835122.1 CDS mutS2 NC_010582.1 400183 402519 D mutS2 family protein 400183..402519 Streptococcus pneumoniae CGSP14 6216988 YP_001835123.1 CDS SPCG_0406 NC_010582.1 402640 402741 R hypothetical protein complement(402640..402741) Streptococcus pneumoniae CGSP14 6218174 YP_001835124.1 CDS dagA NC_010582.1 402862 404184 D sodium:alanine symporter family protein 402862..404184 Streptococcus pneumoniae CGSP14 6217689 YP_001835125.1 CDS mip NC_010582.1 404402 404950 D hypothetical protein 404402..404950 Streptococcus pneumoniae CGSP14 6216851 YP_001835126.1 CDS shetA NC_010582.1 405048 405959 D exfoliative toxin 405048..405959 Streptococcus pneumoniae CGSP14 6217631 YP_001835127.1 CDS serS NC_010582.1 405984 407342 R catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase complement(405984..407342) Streptococcus pneumoniae CGSP14 6217357 YP_001835128.1 CDS SPCG_0411 NC_010582.1 407472 407843 R hypothetical protein complement(407472..407843) Streptococcus pneumoniae CGSP14 6216936 YP_001835129.1 CDS lysC NC_010582.1 407846 409210 R catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; lysine and threonine sensitive; aspartate kinase complement(407846..409210) Streptococcus pneumoniae CGSP14 6216539 YP_001835130.1 CDS phaB NC_010582.1 409579 410349 D Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA; enoyl-CoA hydratase 409579..410349 Streptococcus pneumoniae CGSP14 6218155 YP_001835131.1 CDS SPCG_0414 NC_010582.1 410459 410893 D MarR family transcriptional regulator 410459..410893 Streptococcus pneumoniae CGSP14 6217367 YP_001835132.1 CDS fabH NC_010582.1 410893 411867 D FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; 3-oxoacyl-ACP synthase 410893..411867 Streptococcus pneumoniae CGSP14 6218096 YP_001835133.1 CDS acpP NC_010582.1 411927 412151 D carries the fatty acid chain in fatty acid biosynthesis; acyl carrier protein 411927..412151 Streptococcus pneumoniae CGSP14 6217180 YP_001835134.1 CDS fabK NC_010582.1 412270 413244 D enoyl-(acyl-carrier-protein) reductase 412270..413244 Streptococcus pneumoniae CGSP14 6217209 YP_001835135.1 CDS fabD NC_010582.1 413237 414157 D acyl-carrier-protein S-malonyltransferase 413237..414157 Streptococcus pneumoniae CGSP14 6217133 YP_001835136.1 CDS fabG NC_010582.1 414191 414922 D catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 414191..414922 Streptococcus pneumoniae CGSP14 6217269 YP_001835137.1 CDS fabF NC_010582.1 414935 416179 D FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; 3-oxoacyl-(acyl carrier protein) synthase II 414935..416179 Streptococcus pneumoniae CGSP14 6216943 YP_001835138.1 CDS accB NC_010582.1 416182 416667 D composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxyl carrier protein subunit 416182..416667 Streptococcus pneumoniae CGSP14 6217036 YP_001835139.1 CDS fabZ NC_010582.1 416664 417086 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 416664..417086 Streptococcus pneumoniae CGSP14 6216612 YP_001835140.1 CDS accC NC_010582.1 417098 418465 D an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism; acetyl-CoA carboxylase biotin carboxylase subunit 417098..418465 Streptococcus pneumoniae CGSP14 6218068 YP_001835141.1 CDS accD NC_010582.1 418502 419368 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits; acetyl-CoA carboxylase subunit beta 418502..419368 Streptococcus pneumoniae CGSP14 6218226 YP_001835142.1 CDS accA NC_010582.1 419365 420132 D catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein; these proteins present a shorter N-terminus; acetyl-CoA carboxylase subunit alpha 419365..420132 Streptococcus pneumoniae CGSP14 6218112 YP_001835143.1 CDS SPCG_0426 NC_010582.1 420329 420580 D hypothetical protein 420329..420580 Streptococcus pneumoniae CGSP14 6217617 YP_001835144.1 CDS nusB NC_010582.1 421370 421810 R Regulates rRNA biosynthesis by transcriptional antitermination; transcription antitermination protein NusB complement(421370..421810) Streptococcus pneumoniae CGSP14 6217317 YP_001835145.1 CDS SPCG_0428 NC_010582.1 421785 422174 R hypothetical protein complement(421785..422174) Streptococcus pneumoniae CGSP14 6218227 YP_001835146.1 CDS efp NC_010582.1 422196 422756 R Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA; elongation factor P complement(422196..422756) Streptococcus pneumoniae CGSP14 6216852 YP_001835147.1 CDS gatB NC_010582.1 422885 424327 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B complement(422885..424327) Streptococcus pneumoniae CGSP14 6217339 YP_001835148.1 CDS gatA NC_010582.1 424327 425793 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(424327..425793) Streptococcus pneumoniae CGSP14 6217087 YP_001835149.1 CDS gatC NC_010582.1 425793 426155 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma proteins contain an N-terminal fusion to an unknown domain; aspartyl/glutamyl-tRNA amidotransferase subunit C complement(425793..426155) Streptococcus pneumoniae CGSP14 6216571 YP_001835150.1 CDS prfC NC_010582.1 426308 427852 D stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein; peptide chain release factor 3 426308..427852 Streptococcus pneumoniae CGSP14 6217000 YP_001835151.1 CDS SPCG_0434 NC_010582.1 428107 428304 D hypothetical protein 428107..428304 Streptococcus pneumoniae CGSP14 6216929 YP_001835152.1 CDS SPCG_0435 NC_010582.1 428415 428591 D hypothetical protein 428415..428591 Streptococcus pneumoniae CGSP14 6217746 YP_001835153.1 CDS rpmB NC_010582.1 428707 428895 D required for 70S ribosome assembly; 50S ribosomal protein L28 428707..428895 Streptococcus pneumoniae CGSP14 6217066 YP_001835154.1 CDS asp23 NC_010582.1 429052 429417 D hypothetical protein 429052..429417 Streptococcus pneumoniae CGSP14 6216877 YP_001835155.1 CDS SPCG_0438 NC_010582.1 429420 431087 D hypothetical protein 429420..431087 Streptococcus pneumoniae CGSP14 6217432 YP_001835156.1 CDS ilvB NC_010582.1 431288 432988 D catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit; acetolactate synthase catalytic subunit 431288..432988 Streptococcus pneumoniae CGSP14 6217905 YP_001835157.1 CDS ilvH NC_010582.1 432957 433457 D with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit; acetolactate synthase 3 regulatory subunit 432957..433457 Streptococcus pneumoniae CGSP14 6218172 YP_001835158.1 CDS ilvC NC_010582.1 433523 434545 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 433523..434545 Streptococcus pneumoniae CGSP14 6218374 YP_001835159.1 CDS SPCG_0442 NC_010582.1 434622 434888 D hypothetical protein 434622..434888 Streptococcus pneumoniae CGSP14 6218248 YP_001835160.1 CDS SPCG_0443 NC_010582.1 435126 435482 D hypothetical protein 435126..435482 Streptococcus pneumoniae CGSP14 6216472 YP_001835161.1 CDS ilvA NC_010582.1 435532 436782 D catalyzes the formation of 2-oxobutanoate from L-threonine; biosynthetic; threonine dehydratase 435532..436782 Streptococcus pneumoniae CGSP14 6217042 YP_001835162.1 CDS SPCG_0445 NC_010582.1 436924 437112 D hypothetical protein 436924..437112 Streptococcus pneumoniae CGSP14 6216816 YP_001835163.1 CDS SPCG_0446 NC_010582.1 437666 437881 D hypothetical protein 437666..437881 Streptococcus pneumoniae CGSP14 6217178 YP_001835164.1 CDS glnQ NC_010582.1 437990 438730 R amino acid ABC transporter ATP-binding protein complement(437990..438730) Streptococcus pneumoniae CGSP14 6218304 YP_001835165.1 CDS glnH NC_010582.1 438730 440295 R amino acid ABC transporter amino acid-binding protein/permease complement(438730..440295) Streptococcus pneumoniae CGSP14 6216708 YP_001835166.1 CDS SPCG_0449 NC_010582.1 440430 442322 D hypothetical protein 440430..442322 Streptococcus pneumoniae CGSP14 6218060 YP_001835167.1 CDS SPCG_0450 NC_010582.1 442319 442489 R hypothetical protein complement(442319..442489) Streptococcus pneumoniae CGSP14 6216897 YP_001835168.1 CDS SPCG_0451 NC_010582.1 442701 443171 R degenerate transposase complement(442701..443171) Streptococcus pneumoniae CGSP14 6217297 YP_001835169.1 CDS SPCG_0452 NC_010582.1 443747 444592 D BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell; undecaprenyl pyrophosphate phosphatase 443747..444592 Streptococcus pneumoniae CGSP14 6216924 YP_001835170.1 CDS SPCG_0453 NC_010582.1 444631 445275 R degenerate transposase complement(444631..445275) Streptococcus pneumoniae CGSP14 6218302 YP_001835171.1 CDS SPCG_0454 NC_010582.1 445272 445922 R degenerate transposase complement(445272..445922) Streptococcus pneumoniae CGSP14 6216945 YP_001835172.1 CDS dinP NC_010582.1 446159 447286 R involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function; DNA polymerase IV complement(446159..447286) Streptococcus pneumoniae CGSP14 6217316 YP_001835173.1 CDS pfl NC_010582.1 447568 449892 D formate acetyltransferase 447568..449892 Streptococcus pneumoniae CGSP14 6217550 YP_001835174.1 CDS SPCG_0457 NC_010582.1 450260 450607 R hypothetical protein complement(450260..450607) Streptococcus pneumoniae CGSP14 6218049 YP_001835175.1 CDS SPCG_0458 NC_010582.1 450805 451089 R hypothetical protein complement(450805..451089) Streptococcus pneumoniae CGSP14 6217212 YP_001835176.1 CDS SPCG_0459 NC_010582.1 452664 452888 D PTS system lactose-specific transporter subunit IIBC truncated 452664..452888 Streptococcus pneumoniae CGSP14 6217881 YP_001835177.1 CDS trkH NC_010582.1 453013 454452 R Trk family potassium uptake protein complement(453013..454452) Streptococcus pneumoniae CGSP14 6216479 YP_001835178.1 CDS trkA NC_010582.1 454456 455805 R involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain; potassium transporter peripheral membrane protein complement(454456..455805) Streptococcus pneumoniae CGSP14 6216541 YP_001835179.1 CDS SPCG_0462 NC_010582.1 455966 456841 D hypothetical protein 455966..456841 Streptococcus pneumoniae CGSP14 6216385 YP_001835180.1 CDS SPCG_0463 NC_010582.1 456856 457404 D hypothetical protein 456856..457404 Streptococcus pneumoniae CGSP14 6216725 YP_001835181.1 CDS SPCG_0464 NC_010582.1 457411 457668 D hypothetical protein 457411..457668 Streptococcus pneumoniae CGSP14 6217465 YP_001835182.1 CDS SPCG_0465 NC_010582.1 457770 459452 D ABC transporter ATP-binding protein 457770..459452 Streptococcus pneumoniae CGSP14 6218344 YP_001835183.1 CDS SPCG_0466 NC_010582.1 459437 460267 D hypothetical protein 459437..460267 Streptococcus pneumoniae CGSP14 6217980 YP_001835184.1 CDS cspR NC_010582.1 460421 460963 D RNA methyltransferase 460421..460963 Streptococcus pneumoniae CGSP14 6216721 YP_001835185.1 CDS SPCG_0468 NC_010582.1 461401 461979 D hypothetical protein 461401..461979 Streptococcus pneumoniae CGSP14 6217033 YP_001835186.1 CDS SPCG_0469 NC_010582.1 461969 462619 D PAP2 family protein 461969..462619 Streptococcus pneumoniae CGSP14 6216609 YP_001835187.1 CDS SPCG_0470 NC_010582.1 462647 463036 D hypothetical protein 462647..463036 Streptococcus pneumoniae CGSP14 6217149 YP_001835188.1 CDS SPCG_0471 NC_010582.1 463041 463490 D hypothetical protein 463041..463490 Streptococcus pneumoniae CGSP14 6216821 YP_001835189.1 CDS rpoE NC_010582.1 463603 464205 D participates in both the initiation and recycling phases of transcription; in the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; DNA-directed RNA polymerase subunit delta 463603..464205 Streptococcus pneumoniae CGSP14 6216895 YP_001835190.1 CDS pyrG NC_010582.1 464595 466202 D CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 464595..466202 Streptococcus pneumoniae CGSP14 6218335 YP_001835191.1 CDS SPCG_0474 NC_010582.1 466761 468392 R Na/Pi cotransporter II-like protein complement(466761..468392) Streptococcus pneumoniae CGSP14 6217975 YP_001835192.1 CDS SPCG_0475 NC_010582.1 468594 468704 D hypothetical protein 468594..468704 Streptococcus pneumoniae CGSP14 6218189 YP_001835193.1 CDS SPCG_0476 NC_010582.1 468685 473664 D endo-beta-N-acetylglucosaminidase 468685..473664 Streptococcus pneumoniae CGSP14 6218196 YP_001835194.1 CDS pgk NC_010582.1 473754 474950 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 473754..474950 Streptococcus pneumoniae CGSP14 6217618 YP_001835195.1 CDS SPCG_0478 NC_010582.1 475086 475613 D hypothetical protein 475086..475613 Streptococcus pneumoniae CGSP14 6217712 YP_001835196.1 CDS glnR NC_010582.1 475690 476046 D MerR family transcriptional regulator 475690..476046 Streptococcus pneumoniae CGSP14 6218297 YP_001835197.1 CDS glnA NC_010582.1 476083 477429 D glutamine synthetase, type I 476083..477429 Streptococcus pneumoniae CGSP14 6218347 YP_001835198.1 CDS SPCG_0481 NC_010582.1 477902 478039 D hypothetical protein 477902..478039 Streptococcus pneumoniae CGSP14 6218201 YP_001835199.1 CDS hsdS NC_010582.1 478210 479502 D type I restriction-modification system subunit S 478210..479502 Streptococcus pneumoniae CGSP14 6216540 YP_001835200.1 CDS hsdS NC_010582.1 479450 481000 R type I restriction-modification system subunit S complement(479450..481000) Streptococcus pneumoniae CGSP14 6216546 YP_001835201.1 CDS hsdM NC_010582.1 481000 482463 R type I restriction-modification system, M subunit complement(481000..482463) Streptococcus pneumoniae CGSP14 6217525 YP_001835202.1 CDS hsdR NC_010582.1 482476 484809 R type I restriction-modification system, R subunit complement(482476..484809) Streptococcus pneumoniae CGSP14 6216912 YP_001835203.1 CDS SPCG_0486 NC_010582.1 485159 485287 R hypothetical protein complement(485159..485287) Streptococcus pneumoniae CGSP14 6218467 YP_001835204.1 CDS SPCG_0487 NC_010582.1 485488 485925 D hypothetical protein 485488..485925 Streptococcus pneumoniae CGSP14 6217519 YP_001835205.1 CDS hrcA NC_010582.1 486056 487123 D Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons; heat-inducible transcription repressor 486056..487123 Streptococcus pneumoniae CGSP14 6218184 YP_001835206.1 CDS grpE NC_010582.1 487126 487674 D with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor; heat shock protein GrpE 487126..487674 Streptococcus pneumoniae CGSP14 6216452 YP_001835207.1 CDS dnaK NC_010582.1 488154 489977 D heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 488154..489977 Streptococcus pneumoniae CGSP14 6216882 YP_001835208.1 CDS SPCG_0491 NC_010582.1 491122 492258 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 491122..492258 Streptococcus pneumoniae CGSP14 6217808 YP_001835209.1 CDS SPCG_0492 NC_010582.1 492948 493235 R hypothetical protein complement(492948..493235) Streptococcus pneumoniae CGSP14 6217706 YP_001835210.1 CDS SPCG_0493 NC_010582.1 493245 493655 R HIT family protein complement(493245..493655) Streptococcus pneumoniae CGSP14 6217218 YP_001835211.1 CDS SPCG_0494 NC_010582.1 493723 494454 D ABC transporter ATP-binding protein 493723..494454 Streptococcus pneumoniae CGSP14 6218590 YP_001835212.1 CDS SPCG_0495 NC_010582.1 494451 495500 D ABC transporter permease 494451..495500 Streptococcus pneumoniae CGSP14 6218329 YP_001835213.1 CDS blpT NC_010582.1 495668 495997 R blpT protein, fusion complement(495668..495997) Streptococcus pneumoniae CGSP14 6217897 YP_001835214.1 CDS blpS NC_010582.1 496274 496612 D blpS protein 496274..496612 Streptococcus pneumoniae CGSP14 6216891 YP_001835215.1 CDS SPCG_0498 NC_010582.1 496617 497354 D response regulator BlpR 496617..497354 Streptococcus pneumoniae CGSP14 6217810 YP_001835216.1 CDS SPCG_0499 NC_010582.1 497368 498708 D sensor histidine kinase BlpH 497368..498708 Streptococcus pneumoniae CGSP14 6216648 YP_001835217.1 CDS SPCG_0500 NC_010582.1 498965 500326 R blpC ABC transporter complement(498965..500326) Streptococcus pneumoniae CGSP14 6217916 YP_001835218.1 CDS SPCG_0501 NC_010582.1 500337 502496 R competence factor transporting ATP-binding protein/permease ComA complement(500337..502496) Streptococcus pneumoniae CGSP14 6217270 YP_001835219.1 CDS blpU NC_010582.1 502771 503001 D bacteriocin BlpU 502771..503001 Streptococcus pneumoniae CGSP14 6218508 YP_001835220.1 CDS blpL NC_010582.1 503581 503985 D immunity protein BlpL 503581..503985 Streptococcus pneumoniae CGSP14 6218466 YP_001835221.1 CDS SPCG_0504 NC_010582.1 504183 504371 D IS1381 transposase protein A, truncation 504183..504371 Streptococcus pneumoniae CGSP14 6218427 YP_001835222.1 CDS SPCG_0505 NC_010582.1 504599 504988 D IS1381 transposase protein B 504599..504988 Streptococcus pneumoniae CGSP14 6218354 YP_001835223.1 CDS blpM NC_010582.1 505190 505444 D bacteriocin BlpM 505190..505444 Streptococcus pneumoniae CGSP14 6218198 YP_001835224.1 CDS blpN NC_010582.1 505460 505663 D blpN protein 505460..505663 Streptococcus pneumoniae CGSP14 6218127 YP_001835225.1 CDS blpO NC_010582.1 505895 506056 D bacteriocin BlpO 505895..506056 Streptococcus pneumoniae CGSP14 6218002 YP_001835226.1 CDS blpX NC_010582.1 507050 507448 D immunity protein BlpX 507050..507448 Streptococcus pneumoniae CGSP14 6217974 YP_001835227.1 CDS blpY NC_010582.1 507500 508189 D immunity protein BlpY 507500..508189 Streptococcus pneumoniae CGSP14 6217935 YP_001835228.1 CDS blpZ NC_010582.1 508231 508464 D blpZ protein, fusion 508231..508464 Streptococcus pneumoniae CGSP14 6217917 YP_001835229.1 CDS SPCG_0512 NC_010582.1 508615 509226 D hypothetical protein 508615..509226 Streptococcus pneumoniae CGSP14 6217912 YP_001835230.1 CDS SPCG_0513 NC_010582.1 509387 510181 D hypothetical protein 509387..510181 Streptococcus pneumoniae CGSP14 6217818 YP_001835231.1 CDS trmB NC_010582.1 510178 510813 D tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine; tRNA (guanine-N(7)-)-methyltransferase 510178..510813 Streptococcus pneumoniae CGSP14 6217765 YP_001835232.1 CDS SPCG_0515 NC_010582.1 510868 511419 D in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins; hypothetical protein 510868..511419 Streptococcus pneumoniae CGSP14 6217750 YP_001835233.1 CDS nusA NC_010582.1 511463 512599 D modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 511463..512599 Streptococcus pneumoniae CGSP14 6217609 YP_001835234.1 CDS SPCG_0517 NC_010582.1 512621 512914 D hypothetical protein 512621..512914 Streptococcus pneumoniae CGSP14 6217604 YP_001835235.1 CDS SPCG_0518 NC_010582.1 512907 513206 D hypothetical protein 512907..513206 Streptococcus pneumoniae CGSP14 6217560 YP_001835236.1 CDS infB NC_010582.1 513223 516015 D Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 513223..516015 Streptococcus pneumoniae CGSP14 6217501 YP_001835237.1 CDS rbfA NC_010582.1 516239 516616 D associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock; ribosome-binding factor A 516239..516616 Streptococcus pneumoniae CGSP14 6217485 YP_001835238.1 CDS SPCG_0521 NC_010582.1 516859 517674 D hypothetical protein 516859..517674 Streptococcus pneumoniae CGSP14 6217444 YP_001835239.1 CDS SPCG_0522 NC_010582.1 518045 518278 R hypothetical protein complement(518045..518278) Streptococcus pneumoniae CGSP14 6217436 YP_001835240.1 CDS SPCG_0523 NC_010582.1 518297 518542 D hypothetical protein 518297..518542 Streptococcus pneumoniae CGSP14 6217418 YP_001835241.1 CDS SPCG_0524 NC_010582.1 518542 519876 D hypothetical protein 518542..519876 Streptococcus pneumoniae CGSP14 6217402 YP_001835242.1 CDS SPCG_0525 NC_010582.1 519886 520140 D hypothetical protein 519886..520140 Streptococcus pneumoniae CGSP14 6217310 YP_001835243.1 CDS SPCG_0526 NC_010582.1 520236 520631 D hypothetical protein 520236..520631 Streptococcus pneumoniae CGSP14 6217274 YP_001835244.1 CDS SPCG_0527 NC_010582.1 521004 521438 D hypothetical protein 521004..521438 Streptococcus pneumoniae CGSP14 6217262 YP_001835245.1 CDS SPCG_0528 NC_010582.1 521272 521841 D hypothetical protein 521272..521841 Streptococcus pneumoniae CGSP14 6217232 YP_001835246.1 CDS SPCG_0529 NC_010582.1 521478 522038 D acetyltransferase 521478..522038 Streptococcus pneumoniae CGSP14 6217195 YP_001835247.1 CDS SPCG_0530 NC_010582.1 522023 522616 D hypothetical protein 522023..522616 Streptococcus pneumoniae CGSP14 6217193 YP_001835248.1 CDS valS NC_010582.1 522609 525260 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 522609..525260 Streptococcus pneumoniae CGSP14 6217189 YP_001835249.1 CDS SPCG_0532 NC_010582.1 525341 525505 D type II DNA modification methyltransferase, truncation 525341..525505 Streptococcus pneumoniae CGSP14 6217168 YP_001835250.1 CDS SPCG_0533 NC_010582.1 525453 525548 R hypothetical protein complement(525453..525548) Streptococcus pneumoniae CGSP14 6217157 YP_001835251.1 CDS SPCG_0534 NC_010582.1 525556 527160 D hypothetical protein 525556..527160 Streptococcus pneumoniae CGSP14 6217123 YP_001835252.1 CDS SPCG_0535 NC_010582.1 527540 528343 D cell filamentation protein Fic-like protein 527540..528343 Streptococcus pneumoniae CGSP14 6217112 YP_001835253.1 CDS SPCG_0536 NC_010582.1 528459 529040 R IS3-Spn1 transposase, truncation complement(528459..529040) Streptococcus pneumoniae CGSP14 6217074 YP_001835254.1 CDS SPCG_0537 NC_010582.1 529517 529729 R degenerate transposase complement(529517..529729) Streptococcus pneumoniae CGSP14 6217069 YP_001835255.1 CDS SPCG_0538 NC_010582.1 530200 531348 D hypothetical protein 530200..531348 Streptococcus pneumoniae CGSP14 6217064 YP_001835256.1 CDS SPCG_0539 NC_010582.1 531444 531539 D hypothetical protein 531444..531539 Streptococcus pneumoniae CGSP14 6217049 YP_001835257.1 CDS SPCG_0540 NC_010582.1 531564 532106 D hypothetical protein 531564..532106 Streptococcus pneumoniae CGSP14 6217003 YP_001835258.1 CDS SPCG_0541 NC_010582.1 532130 532762 D hypothetical protein 532130..532762 Streptococcus pneumoniae CGSP14 6216999 YP_001835259.1 CDS licT NC_010582.1 533062 533901 D transcription antiterminator Lict 533062..533901 Streptococcus pneumoniae CGSP14 6216996 YP_001835260.1 CDS SPCG_0543 NC_010582.1 533919 535757 D PTS system beta-glucosides-specific transporter subunit IIABC 533919..535757 Streptococcus pneumoniae CGSP14 6216991 YP_001835261.1 CDS SPCG_0544 NC_010582.1 535770 537185 D 6-phospho-beta-glucosidase 535770..537185 Streptococcus pneumoniae CGSP14 6216986 YP_001835262.1 CDS pheS NC_010582.1 537695 538822 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 537695..538822 Streptococcus pneumoniae CGSP14 6216979 YP_001835263.1 CDS SPCG_0546 NC_010582.1 538822 539331 D acetyltransferase 538822..539331 Streptococcus pneumoniae CGSP14 6216930 YP_001835264.1 CDS pheT NC_010582.1 539408 541813 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 539408..541813 Streptococcus pneumoniae CGSP14 6216918 YP_001835265.1 CDS SPCG_0548 NC_010582.1 541881 542882 R hypothetical protein complement(541881..542882) Streptococcus pneumoniae CGSP14 6216917 YP_001835266.1 CDS SPCG_0549 NC_010582.1 543038 543532 D IS1239 transposase, truncation 543038..543532 Streptococcus pneumoniae CGSP14 6216880 YP_001835267.1 CDS SPCG_0550 NC_010582.1 543611 543877 D transcriptional regulator 543611..543877 Streptococcus pneumoniae CGSP14 6216868 YP_001835268.1 CDS metE NC_010582.1 543958 546387 D catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 543958..546387 Streptococcus pneumoniae CGSP14 6216859 YP_001835269.1 CDS metF NC_010582.1 546451 547317 D 5,10-methylenetetrahydrofolate reductase 546451..547317 Streptococcus pneumoniae CGSP14 6216853 YP_001835270.1 CDS pnpA NC_010582.1 547888 550215 D polynucleotide phosphorylase/polyadenylase 547888..550215 Streptococcus pneumoniae CGSP14 6216845 YP_001835271.1 CDS cysE NC_010582.1 550231 550848 D serine acetyltransferase 550231..550848 Streptococcus pneumoniae CGSP14 6216837 YP_001835272.1 CDS SPCG_0555 NC_010582.1 550860 551744 D acetyltransferase 550860..551744 Streptococcus pneumoniae CGSP14 6216797 YP_001835273.1 CDS cysS NC_010582.1 551831 553174 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 551831..553174 Streptococcus pneumoniae CGSP14 6216792 YP_001835274.1 CDS SPCG_0557 NC_010582.1 553167 553553 D hypothetical protein 553167..553553 Streptococcus pneumoniae CGSP14 6216790 YP_001835275.1 CDS SPCG_0558 NC_010582.1 553557 554441 D leucine-rich protein 553557..554441 Streptococcus pneumoniae CGSP14 6216789 YP_001835276.1 CDS SPCG_0559 NC_010582.1 554905 555282 D hypothetical protein 554905..555282 Streptococcus pneumoniae CGSP14 6216752 YP_001835277.1 CDS SPCG_0560 NC_010582.1 555953 557230 D transmembrane protein Vexp1 555953..557230 Streptococcus pneumoniae CGSP14 6216705 YP_001835278.1 CDS SPCG_0561 NC_010582.1 557243 557890 D ABC transporter ATP-binding protein 557243..557890 Streptococcus pneumoniae CGSP14 6216670 YP_001835279.1 CDS SPCG_0562 NC_010582.1 557942 559321 D transmembrane protein Vexp3 557942..559321 Streptococcus pneumoniae CGSP14 6216637 YP_001835280.1 CDS pep27 NC_010582.1 559492 559584 D pep27 protein 559492..559584 Streptococcus pneumoniae CGSP14 6216619 YP_001835281.1 CDS vncR NC_010582.1 559633 560289 D DNA-binding response regulator VncR 559633..560289 Streptococcus pneumoniae CGSP14 6216593 YP_001835282.1 CDS vncS NC_010582.1 560286 561614 D sensor histidine kinase VncS 560286..561614 Streptococcus pneumoniae CGSP14 6216585 YP_001835283.1 CDS fba NC_010582.1 561755 562636 D catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate; fructose-bisphosphate aldolase 561755..562636 Streptococcus pneumoniae CGSP14 6216580 YP_001835284.1 CDS SPCG_0567 NC_010582.1 562957 564159 R oxidoreductase complement(562957..564159) Streptococcus pneumoniae CGSP14 6216565 YP_001835285.1 CDS SPCG_0568 NC_010582.1 564442 565101 R amino acid ABC transporter permease complement(564442..565101) Streptococcus pneumoniae CGSP14 6216478 YP_001835286.1 CDS SPCG_0569 NC_010582.1 565111 565788 R amino acid ABC transporter permease complement(565111..565788) Streptococcus pneumoniae CGSP14 6216468 YP_001835287.1 CDS SPCG_0570 NC_010582.1 565801 566682 R amino acid ABC transporter amino acid-binding protein complement(565801..566682) Streptococcus pneumoniae CGSP14 6216453 YP_001835288.1 CDS SPCG_0571 NC_010582.1 566606 567376 R amino acid ABC transporter ATP-binding protein complement(566606..567376) Streptococcus pneumoniae CGSP14 6216451 YP_001835289.1 CDS recJ NC_010582.1 567629 569863 D single-stranded-DNA-specific exonuclease RecJ 567629..569863 Streptococcus pneumoniae CGSP14 6216445 YP_001835290.1 CDS SPCG_0573 NC_010582.1 570038 571699 D metallo-beta-lactamase superfamily protein 570038..571699 Streptococcus pneumoniae CGSP14 6216410 YP_001835291.1 CDS estA NC_010582.1 571768 572547 D tributyrin esterase 571768..572547 Streptococcus pneumoniae CGSP14 6218364 YP_001835292.1 CDS murM NC_010582.1 572660 573880 D beta-lactam resistance factor 572660..573880 Streptococcus pneumoniae CGSP14 6217104 YP_001835293.1 CDS murN NC_010582.1 573885 575117 D beta-lactam resistance factor 573885..575117 Streptococcus pneumoniae CGSP14 6217766 YP_001835294.1 CDS SPCG_0577 NC_010582.1 575175 575897 D hypothetical protein 575175..575897 Streptococcus pneumoniae CGSP14 6217148 YP_001835295.1 CDS uvrC NC_010582.1 575937 577784 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 575937..577784 Streptococcus pneumoniae CGSP14 6217024 YP_001835296.1 CDS SPCG_0579 NC_010582.1 577834 578271 D hypothetical protein 577834..578271 Streptococcus pneumoniae CGSP14 6216831 YP_001835297.1 CDS SPCG_0580 NC_010582.1 578272 578607 D hypothetical protein 578272..578607 Streptococcus pneumoniae CGSP14 6216879 YP_001835298.1 CDS SPCG_0581 NC_010582.1 578791 579606 R amino acid ABC transporter amino acid-binding protein complement(578791..579606) Streptococcus pneumoniae CGSP14 6217454 YP_001835299.1 CDS SPCG_0582 NC_010582.1 579665 579775 D hypothetical protein 579665..579775 Streptococcus pneumoniae CGSP14 6217493 YP_001835300.1 CDS nrd NC_010582.1 579762 580367 D nitroreductase family protein 579762..580367 Streptococcus pneumoniae CGSP14 6216985 YP_001835301.1 CDS pepV NC_010582.1 580380 581780 D divalent metal ion-dependent extracellular dipeptidase; able to hydrolyze a broad range of dipeptides but no tri-, tetra-, or larger oligopeptides; differences in the amino acid specificity of the cleavage site varies between species; similar to succinyl-diaminopimelate desuccinylases; dipeptidase PepV 580380..581780 Streptococcus pneumoniae CGSP14 6218124 YP_001835302.1 CDS SPCG_0585 NC_010582.1 581834 582412 D hypothetical protein 581834..582412 Streptococcus pneumoniae CGSP14 6217190 YP_001835303.1 CDS SPCG_0586 NC_010582.1 582536 582724 D hypothetical protein 582536..582724 Streptococcus pneumoniae CGSP14 6218592 YP_001835304.1 CDS brnQ NC_010582.1 583015 584355 D branched-chain amino acid transport system II carrier protein 583015..584355 Streptococcus pneumoniae CGSP14 6218230 YP_001835305.1 CDS SPCG_0588 NC_010582.1 584559 585596 D hypothetical protein 584559..585596 Streptococcus pneumoniae CGSP14 6217191 YP_001835306.1 CDS SPCG_0589 NC_010582.1 585565 586068 D HIT family protein 585565..586068 Streptococcus pneumoniae CGSP14 6217018 YP_001835307.1 CDS SPCG_0590 NC_010582.1 586071 586787 D hypothetical protein 586071..586787 Streptococcus pneumoniae CGSP14 6217057 YP_001835308.1 CDS rplK NC_010582.1 587096 587521 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 587096..587521 Streptococcus pneumoniae CGSP14 6217726 YP_001835309.1 CDS rplA NC_010582.1 587729 588418 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 587729..588418 Streptococcus pneumoniae CGSP14 6218350 YP_001835310.1 CDS SPCG_0593 NC_010582.1 589020 589532 D hypothetical protein 589020..589532 Streptococcus pneumoniae CGSP14 6217019 YP_001835311.1 CDS SPCG_0594 NC_010582.1 590577 591569 D ABC transporter ATP-binding protein 590577..591569 Streptococcus pneumoniae CGSP14 6218343 YP_001835312.1 CDS SPCG_0595 NC_010582.1 591529 592389 D membrane protein 591529..592389 Streptococcus pneumoniae CGSP14 6216709 YP_001835313.1 CDS SPCG_0596 NC_010582.1 592391 593176 D hypothetical protein 592391..593176 Streptococcus pneumoniae CGSP14 6216635 YP_001835314.1 CDS SPCG_0597 NC_010582.1 593274 593492 D hypothetical protein 593274..593492 Streptococcus pneumoniae CGSP14 6216572 YP_001835315.1 CDS SPCG_0598 NC_010582.1 593429 593638 D hypothetical protein 593429..593638 Streptococcus pneumoniae CGSP14 6216993 YP_001835316.1 CDS prtA NC_010582.1 594362 600796 D serine protease 594362..600796 Streptococcus pneumoniae CGSP14 6218240 YP_001835317.1 CDS SPCG_0600 NC_010582.1 601407 601904 D PTS system transporter subunit IIA 601407..601904 Streptococcus pneumoniae CGSP14 6216872 YP_001835318.1 CDS SPCG_0601 NC_010582.1 601942 602247 D PTS system transporter subunit IIB 601942..602247 Streptococcus pneumoniae CGSP14 6217219 YP_001835319.1 CDS SPCG_0602 NC_010582.1 602295 603770 D PTS system transporter subunit IIC 602295..603770 Streptococcus pneumoniae CGSP14 6216828 YP_001835320.1 CDS bgaA NC_010582.1 604120 610821 D beta-galactosidase 604120..610821 Streptococcus pneumoniae CGSP14 6216512 YP_001835321.1 CDS SPCG_0604 NC_010582.1 611131 611685 R degenerate transposase complement(611131..611685) Streptococcus pneumoniae CGSP14 6217911 YP_001835322.1 CDS SPCG_0605 NC_010582.1 611673 611918 R degenerate transposase complement(611673..611918) Streptococcus pneumoniae CGSP14 6216583 YP_001835323.1 CDS SPCG_0606 NC_010582.1 612129 612449 R hypothetical protein complement(612129..612449) Streptococcus pneumoniae CGSP14 6218231 YP_001835324.1 CDS SPCG_0607 NC_010582.1 612424 613089 D hypothetical protein 612424..613089 Streptococcus pneumoniae CGSP14 6218322 YP_001835325.1 CDS SPCG_0608 NC_010582.1 613090 613536 D Fe-S oxidoreductase 613090..613536 Streptococcus pneumoniae CGSP14 6216750 YP_001835326.1 CDS SPCG_0609 NC_010582.1 613514 614077 D hypothetical protein 613514..614077 Streptococcus pneumoniae CGSP14 6217340 YP_001835327.1 CDS SPCG_0610 NC_010582.1 614101 614325 D hypothetical protein 614101..614325 Streptococcus pneumoniae CGSP14 6217683 YP_001835328.1 CDS SPCG_0611 NC_010582.1 614300 614401 D hypothetical protein 614300..614401 Streptococcus pneumoniae CGSP14 6216530 YP_001835329.1 CDS SPCG_0612 NC_010582.1 614376 616391 D sodium/hydrogen exchanger family protein 614376..616391 Streptococcus pneumoniae CGSP14 6216415 YP_001835330.1 CDS SPCG_0613 NC_010582.1 616555 617430 D ribonuclease BN 616555..617430 Streptococcus pneumoniae CGSP14 6218306 YP_001835331.1 CDS ccdA NC_010582.1 617641 618351 D cytochrome c-type biogenesis protein CcdA 617641..618351 Streptococcus pneumoniae CGSP14 6217353 YP_001835332.1 CDS SPCG_0615 NC_010582.1 618344 618937 D thioredoxin 618344..618937 Streptococcus pneumoniae CGSP14 6217709 YP_001835333.1 CDS msrA NC_010582.1 618948 620060 D bifunctional methionine sulfoxide reductase A/B 618948..620060 Streptococcus pneumoniae CGSP14 6217930 YP_001835334.1 CDS SPCG_0617 NC_010582.1 620400 621155 D DNA-binding response regulator 620400..621155 Streptococcus pneumoniae CGSP14 6217175 YP_001835335.1 CDS SPCG_0618 NC_010582.1 621152 622843 D sensor histidine kinase 621152..622843 Streptococcus pneumoniae CGSP14 6217893 YP_001835336.1 CDS SPCG_0619 NC_010582.1 622938 623522 D hypothetical protein 622938..623522 Streptococcus pneumoniae CGSP14 6217145 YP_001835337.1 CDS zmpB NC_010582.1 623544 629486 D zinc metalloprotease ZmpB 623544..629486 Streptococcus pneumoniae CGSP14 6217389 YP_001835338.1 CDS SPCG_0621 NC_010582.1 629547 631268 D chorismate binding protein 629547..631268 Streptococcus pneumoniae CGSP14 6218188 YP_001835339.1 CDS SPCG_0622 NC_010582.1 631269 631877 D hypothetical protein 631269..631877 Streptococcus pneumoniae CGSP14 6217610 YP_001835340.1 CDS SPCG_0623 NC_010582.1 631936 632934 D surface protein 631936..632934 Streptococcus pneumoniae CGSP14 6216975 YP_001835341.1 CDS glcK NC_010582.1 633043 634020 D glucokinase 633043..634020 Streptococcus pneumoniae CGSP14 6217415 YP_001835342.1 CDS thyA NC_010582.1 634117 634956 D ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived; thymidylate synthase 634117..634956 Streptococcus pneumoniae CGSP14 6218455 YP_001835343.1 CDS SPCG_0626 NC_010582.1 635004 635174 R hypothetical protein complement(635004..635174) Streptococcus pneumoniae CGSP14 6216860 YP_001835344.1 CDS SPCG_0627 NC_010582.1 635050 635238 D hypothetical protein 635050..635238 Streptococcus pneumoniae CGSP14 6217072 YP_001835345.1 CDS miaA NC_010582.1 635244 636179 D IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity; tRNA delta(2)-isopentenylpyrophosphate transferase 635244..636179 Streptococcus pneumoniae CGSP14 6216560 YP_001835346.1 CDS SPCG_0629 NC_010582.1 636172 637410 D GTP-binding protein HflX 636172..637410 Streptococcus pneumoniae CGSP14 6217246 YP_001835347.1 CDS SPCG_0630 NC_010582.1 637403 638026 D hypothetical protein 637403..638026 Streptococcus pneumoniae CGSP14 6218533 YP_001835348.1 CDS SPCG_0631 NC_010582.1 638041 638970 D member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions; ribonuclease Z 638041..638970 Streptococcus pneumoniae CGSP14 6216630 YP_001835349.1 CDS SPCG_0632 NC_010582.1 638991 639746 D short chain dehydrogenase/reductase family oxidoreductase 638991..639746 Streptococcus pneumoniae CGSP14 6218093 YP_001835350.1 CDS SPCG_0633 NC_010582.1 639800 640798 R transcriptional regulator complement(639800..640798) Streptococcus pneumoniae CGSP14 6217809 YP_001835351.1 CDS SPCG_0634 NC_010582.1 640772 641041 D hypothetical protein 640772..641041 Streptococcus pneumoniae CGSP14 6217932 YP_001835352.1 CDS SPCG_0635 NC_010582.1 641041 641421 D hypothetical protein 641041..641421 Streptococcus pneumoniae CGSP14 6218210 YP_001835353.1 CDS SPCG_0636 NC_010582.1 641540 641737 D hypothetical protein 641540..641737 Streptococcus pneumoniae CGSP14 6216422 YP_001835354.1 CDS rsuA NC_010582.1 641777 642502 R ribosomal small subunit pseudouridine synthase A complement(641777..642502) Streptococcus pneumoniae CGSP14 6218162 YP_001835355.1 CDS SPCG_0638 NC_010582.1 642643 644505 D elongation factor Tu family protein 642643..644505 Streptococcus pneumoniae CGSP14 6216906 YP_001835356.1 CDS SPCG_0639 NC_010582.1 644525 644779 D hypothetical protein 644525..644779 Streptococcus pneumoniae CGSP14 6217966 YP_001835357.1 CDS SPCG_0640 NC_010582.1 645326 645442 D hypothetical protein 645326..645442 Streptococcus pneumoniae CGSP14 6218346 YP_001835358.1 CDS SPCG_0641 NC_010582.1 645513 647534 D hypothetical protein 645513..647534 Streptococcus pneumoniae CGSP14 6218542 YP_001835359.1 CDS SPCG_0642 NC_010582.1 647536 648177 D ABC transporter ATP-binding protein 647536..648177 Streptococcus pneumoniae CGSP14 6218097 YP_001835360.1 CDS murD NC_010582.1 648281 649633 D UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation; UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase 648281..649633 Streptococcus pneumoniae CGSP14 6216810 YP_001835361.1 CDS murG NC_010582.1 649635 650693 D UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis; undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase 649635..650693 Streptococcus pneumoniae CGSP14 6216884 YP_001835362.1 CDS divIB NC_010582.1 650703 651902 D cell division protein DivIB 650703..651902 Streptococcus pneumoniae CGSP14 6218173 YP_001835363.1 CDS SPCG_0646 NC_010582.1 652012 652158 D hypothetical protein 652012..652158 Streptococcus pneumoniae CGSP14 6217130 YP_001835364.1 CDS SPCG_0647 NC_010582.1 652170 652301 D hypothetical protein 652170..652301 Streptococcus pneumoniae CGSP14 6217277 YP_001835365.1 CDS SPCG_0648 NC_010582.1 652642 653490 D hypothetical protein 652642..653490 Streptococcus pneumoniae CGSP14 6217089 YP_001835366.1 CDS SPCG_0649 NC_010582.1 653820 654560 D HesA/MoeB/ThiF family protein 653820..654560 Streptococcus pneumoniae CGSP14 6216900 YP_001835367.1 CDS SPCG_0650 NC_010582.1 655000 655875 D ABC transporter ATP-binding protein 655000..655875 Streptococcus pneumoniae CGSP14 6217498 YP_001835368.1 CDS SPCG_0651 NC_010582.1 655868 656581 D hypothetical protein 655868..656581 Streptococcus pneumoniae CGSP14 6217715 YP_001835369.1 CDS SPCG_0652 NC_010582.1 656855 656998 R hypothetical protein complement(656855..656998) Streptococcus pneumoniae CGSP14 6218339 YP_001835370.1 CDS pyrF NC_010582.1 657316 658017 D type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase; orotidine 5'-phosphate decarboxylase 657316..658017 Streptococcus pneumoniae CGSP14 6217327 YP_001835371.1 CDS pyrE NC_010582.1 658051 658683 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 658051..658683 Streptococcus pneumoniae CGSP14 6217993 YP_001835372.1 CDS SPCG_0655 NC_010582.1 659362 660126 D hypothetical protein 659362..660126 Streptococcus pneumoniae CGSP14 6217128 YP_001835373.1 CDS SPCG_0656 NC_010582.1 660881 661585 D hypothetical protein 660881..661585 Streptococcus pneumoniae CGSP14 6216784 YP_001835374.1 CDS SPCG_0657 NC_010582.1 661582 662229 D ABC transporter ATP-binding protein 661582..662229 Streptococcus pneumoniae CGSP14 6218525 YP_001835375.1 CDS SPCG_0658 NC_010582.1 662309 663169 R amino acid (glutamine) ABC transporter substrate binding protein complement(662309..663169) Streptococcus pneumoniae CGSP14 6218336 YP_001835376.1 CDS SPCG_0659 NC_010582.1 663181 663939 R amino acid ABC transporter ATP-binding protein complement(663181..663939) Streptococcus pneumoniae CGSP14 6217697 YP_001835377.1 CDS SPCG_0660 NC_010582.1 663940 664857 R amino acid ABC transporter permease complement(663940..664857) Streptococcus pneumoniae CGSP14 6216465 YP_001835378.1 CDS SPCG_0661 NC_010582.1 664890 665036 D hypothetical protein 664890..665036 Streptococcus pneumoniae CGSP14 6218018 YP_001835379.1 CDS lysS NC_010582.1 665164 666654 D class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1; lysyl-tRNA synthetase 665164..666654 Streptococcus pneumoniae CGSP14 6218396 YP_001835380.1 CDS lctO NC_010582.1 667278 668414 D lactate oxidase 667278..668414 Streptococcus pneumoniae CGSP14 6218437 YP_001835381.1 CDS SPCG_0664 NC_010582.1 668971 669639 D transcriptional regulator 668971..669639 Streptococcus pneumoniae CGSP14 6216554 YP_001835382.1 CDS SPCG_0665 NC_010582.1 669636 669881 R hypothetical protein complement(669636..669881) Streptococcus pneumoniae CGSP14 6216657 YP_001835383.1 CDS thiM NC_010582.1 669944 670747 D catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP; hydroxyethylthiazole kinase 669944..670747 Streptococcus pneumoniae CGSP14 6217806 YP_001835384.1 CDS thiE NC_010582.1 670749 671378 D thiamine-phosphate pyrophosphorylase 670749..671378 Streptococcus pneumoniae CGSP14 6216545 YP_001835385.1 CDS SPCG_0668 NC_010582.1 671937 672497 D hypothetical protein 671937..672497 Streptococcus pneumoniae CGSP14 6217729 YP_001835386.1 CDS SPCG_0669 NC_010582.1 672498 673883 D ABC transporter ATP-binding protein 672498..673883 Streptococcus pneumoniae CGSP14 6217704 YP_001835387.1 CDS SPCG_0670 NC_010582.1 673885 674535 D hypothetical protein 673885..674535 Streptococcus pneumoniae CGSP14 6216925 YP_001835388.1 CDS tenA NC_010582.1 674546 675238 D transcriptional activator TenA 674546..675238 Streptococcus pneumoniae CGSP14 6217226 YP_001835389.1 CDS SPCG_0672 NC_010582.1 675243 675767 D hypothetical protein 675243..675767 Streptococcus pneumoniae CGSP14 6218139 YP_001835390.1 CDS thiM NC_010582.1 675764 676570 D hydroxyethylthiazole kinase 675764..676570 Streptococcus pneumoniae CGSP14 6217830 YP_001835391.1 CDS thiE NC_010582.1 676563 677195 D Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate to form thiamine monophosphate; thiamine-phosphate pyrophosphorylase 676563..677195 Streptococcus pneumoniae CGSP14 6217775 YP_001835392.1 CDS thiD NC_010582.1 677405 678196 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(677405..678196) Streptococcus pneumoniae CGSP14 6216672 YP_001835393.1 CDS copY NC_010582.1 678532 678957 D transcriptional repressor 678532..678957 Streptococcus pneumoniae CGSP14 6217169 YP_001835394.1 CDS SPCG_0677 NC_010582.1 678968 679339 D hypothetical protein 678968..679339 Streptococcus pneumoniae CGSP14 6218136 YP_001835395.1 CDS ctpA NC_010582.1 679340 681592 D cation transporter E1-E2 family ATPase 679340..681592 Streptococcus pneumoniae CGSP14 6217686 YP_001835396.1 CDS spxB NC_010582.1 681799 683574 D pyruvate oxidase 681799..683574 Streptococcus pneumoniae CGSP14 6216487 YP_001835397.1 CDS SPCG_0680 NC_010582.1 683685 684032 D hypothetical protein 683685..684032 Streptococcus pneumoniae CGSP14 6218591 YP_001835398.1 CDS SPCG_0681 NC_010582.1 684244 684660 R hypothetical protein complement(684244..684660) Streptococcus pneumoniae CGSP14 6217639 YP_001835399.1 CDS SPCG_0682 NC_010582.1 684689 684955 R hypothetical protein complement(684689..684955) Streptococcus pneumoniae CGSP14 6218151 YP_001835400.1 CDS SPCG_0683 NC_010582.1 685292 685387 R hypothetical protein complement(685292..685387) Streptococcus pneumoniae CGSP14 6216899 YP_001835401.1 CDS SPCG_0684 NC_010582.1 685452 685733 D 6-phospho-beta-glucosidase 685452..685733 Streptococcus pneumoniae CGSP14 6217238 YP_001835402.1 CDS SPCG_0685 NC_010582.1 685811 686809 D mannose-6-phosphate isomerase 685811..686809 Streptococcus pneumoniae CGSP14 6217724 YP_001835403.1 CDS SPCG_0686 NC_010582.1 686793 686996 D hypothetical protein 686793..686996 Streptococcus pneumoniae CGSP14 6218308 YP_001835404.1 CDS SPCG_0687 NC_010582.1 686830 688089 R sodium-dependent transporter complement(686830..688089) Streptococcus pneumoniae CGSP14 6218520 YP_001835405.1 CDS SPCG_0688 NC_010582.1 688086 688313 R hypothetical protein complement(688086..688313) Streptococcus pneumoniae CGSP14 6217107 YP_001835406.1 CDS SPCG_0689 NC_010582.1 688412 689152 D MerR family transcriptional regulator 688412..689152 Streptococcus pneumoniae CGSP14 6217326 YP_001835407.1 CDS SPCG_0690 NC_010582.1 689181 689636 R mutT/nudix family protein complement(689181..689636) Streptococcus pneumoniae CGSP14 6217359 YP_001835408.1 CDS SPCG_0691 NC_010582.1 689656 690849 R hypothetical protein complement(689656..690849) Streptococcus pneumoniae CGSP14 6217594 YP_001835409.1 CDS SPCG_0692 NC_010582.1 690890 691735 R hypothetical protein complement(690890..691735) Streptococcus pneumoniae CGSP14 6217164 YP_001835410.1 CDS SPCG_0693 NC_010582.1 691860 692417 D TetR family transcriptional regulator 691860..692417 Streptococcus pneumoniae CGSP14 6217173 YP_001835411.1 CDS SPCG_0694 NC_010582.1 692436 692903 D cytidine and deoxycytidylate deaminase family protein 692436..692903 Streptococcus pneumoniae CGSP14 6218355 YP_001835412.1 CDS upp NC_010582.1 692971 693621 D Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate; uracil phosphoribosyltransferase 692971..693621 Streptococcus pneumoniae CGSP14 6217848 YP_001835413.1 CDS clpP NC_010582.1 693794 694384 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 693794..694384 Streptococcus pneumoniae CGSP14 6218370 YP_001835414.1 CDS SPCG_0697 NC_010582.1 694381 694479 R hypothetical protein complement(694381..694479) Streptococcus pneumoniae CGSP14 6218031 YP_001835415.1 CDS SPCG_0698 NC_010582.1 694463 694711 D hypothetical protein 694463..694711 Streptococcus pneumoniae CGSP14 6216741 YP_001835416.1 CDS SPCG_0699 NC_010582.1 694813 695973 D branched-chain amino acid ABC transporter substrate-binding protein 694813..695973 Streptococcus pneumoniae CGSP14 6216802 YP_001835417.1 CDS SPCG_0700 NC_010582.1 696232 697110 D branched-chain amino acid ABC transporter permease 696232..697110 Streptococcus pneumoniae CGSP14 6217661 YP_001835418.1 CDS SPCG_0701 NC_010582.1 697114 698070 D branched-chain amino acid ABC transporter permease 697114..698070 Streptococcus pneumoniae CGSP14 6218361 YP_001835419.1 CDS SPCG_0702 NC_010582.1 698070 698834 D branched-chain amino acid ABC transporter ATP-binding protein 698070..698834 Streptococcus pneumoniae CGSP14 6218314 YP_001835420.1 CDS SPCG_0703 NC_010582.1 698834 699544 D branched-chain amino acid ABC transporter ATP-binding protein 698834..699544 Streptococcus pneumoniae CGSP14 6218365 YP_001835421.1 CDS SPCG_0704 NC_010582.1 699958 700614 D acetoin utilization protein AcuB 699958..700614 Streptococcus pneumoniae CGSP14 6216544 YP_001835422.1 CDS prfB NC_010582.1 700828 701817 D recognizes the termination signals UGA and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF2; in some organisms control of PrfB protein levels is maintained through a +1 ribosomal frameshifting mechanism; this protein is similar to release factor 1; peptide chain release factor 2 700828..701817 Streptococcus pneumoniae CGSP14 6216734 YP_001835423.1 CDS ftsE NC_010582.1 701835 702527 D cell division ABC transporter ATP-binding protein FtsE 701835..702527 Streptococcus pneumoniae CGSP14 6216668 YP_001835424.1 CDS ftsX NC_010582.1 702457 703446 D cell division ABC transporter permease FtsX 702457..703446 Streptococcus pneumoniae CGSP14 6216429 YP_001835425.1 CDS ptsG NC_010582.1 703732 705912 D PTS system transporter subunit IIABC 703732..705912 Streptococcus pneumoniae CGSP14 6217350 YP_001835426.1 CDS SPCG_0709 NC_010582.1 705918 706037 D hypothetical protein 705918..706037 Streptococcus pneumoniae CGSP14 6217855 YP_001835427.1 CDS SPCG_0710 NC_010582.1 706030 706779 D hypothetical protein 706030..706779 Streptococcus pneumoniae CGSP14 6218144 YP_001835428.1 CDS rheB NC_010582.1 706919 708262 D DEAD/DEAH box helicase 706919..708262 Streptococcus pneumoniae CGSP14 6218363 YP_001835429.1 CDS metK NC_010582.1 708477 709667 D catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 708477..709667 Streptococcus pneumoniae CGSP14 6218451 YP_001835430.1 CDS SPCG_0713 NC_010582.1 710220 711155 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; subclass 1A is a dimer formed by two identical PyrD subunits each containing an FMN group; dihydroorotate dehydrogenase 1A 710220..711155 Streptococcus pneumoniae CGSP14 6216486 YP_001835431.1 CDS holA NC_010582.1 711189 712226 D required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA; DNA polymerase III subunit delta 711189..712226 Streptococcus pneumoniae CGSP14 6218362 YP_001835432.1 CDS sodA NC_010582.1 712399 713004 D superoxide dismutase, manganese-dependent 712399..713004 Streptococcus pneumoniae CGSP14 6217646 YP_001835433.1 CDS SPCG_0716 NC_010582.1 713162 713692 D hypothetical protein 713162..713692 Streptococcus pneumoniae CGSP14 6217437 YP_001835434.1 CDS SPCG_0717 NC_010582.1 713713 714798 D 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance; ribosomal RNA large subunit methyltransferase N 713713..714798 Streptococcus pneumoniae CGSP14 6216443 YP_001835435.1 CDS SPCG_0718 NC_010582.1 714798 715280 D vanZF-related protein 714798..715280 Streptococcus pneumoniae CGSP14 6218547 YP_001835436.1 CDS SPCG_0719 NC_010582.1 715282 716823 D ABC transporter ATP-binding protein 715282..716823 Streptococcus pneumoniae CGSP14 6218373 YP_001835437.1 CDS ppiA NC_010582.1 716879 717682 R cyclophilin type peptidyl-prolyl cis-trans isomerase complement(716879..717682) Streptococcus pneumoniae CGSP14 6218317 YP_001835438.1 CDS SPCG_0721 NC_010582.1 717766 717978 R hypothetical protein complement(717766..717978) Streptococcus pneumoniae CGSP14 6218299 YP_001835439.1 CDS SPCG_0722 NC_010582.1 718457 718666 R hypothetical protein complement(718457..718666) Streptococcus pneumoniae CGSP14 6216849 YP_001835440.1 CDS rpsP NC_010582.1 718836 719123 D 30S ribosomal protein S16 718836..719123 Streptococcus pneumoniae CGSP14 6216876 YP_001835441.1 CDS SPCG_0724 NC_010582.1 719127 719366 D KH domain-containing protein 719127..719366 Streptococcus pneumoniae CGSP14 6218195 YP_001835442.1 CDS SPCG_0725 NC_010582.1 719931 720731 D hypothetical protein 719931..720731 Streptococcus pneumoniae CGSP14 6217273 YP_001835443.1 CDS rimM NC_010582.1 720762 721280 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 720762..721280 Streptococcus pneumoniae CGSP14 6218461 YP_001835444.1 CDS trmD NC_010582.1 721270 721989 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 721270..721989 Streptococcus pneumoniae CGSP14 6216647 YP_001835445.1 CDS SPCG_0728 NC_010582.1 722001 722339 D ATP cone domain-containing protein 722001..722339 Streptococcus pneumoniae CGSP14 6218020 YP_001835446.1 CDS SPCG_0729 NC_010582.1 722370 722690 R hypothetical protein complement(722370..722690) Streptococcus pneumoniae CGSP14 6216559 YP_001835447.1 CDS SPCG_0730 NC_010582.1 722764 723003 D hypothetical protein 722764..723003 Streptococcus pneumoniae CGSP14 6217307 YP_001835448.1 CDS SPCG_0731 NC_010582.1 723000 723128 R hypothetical protein complement(723000..723128) Streptococcus pneumoniae CGSP14 6217004 YP_001835449.1 CDS SPCG_0732 NC_010582.1 723255 723791 R hypothetical protein complement(723255..723791) Streptococcus pneumoniae CGSP14 6217288 YP_001835450.1 CDS gor NC_010582.1 723964 725334 R catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; glutathione reductase complement(723964..725334) Streptococcus pneumoniae CGSP14 6218036 YP_001835451.1 CDS SPCG_0734 NC_010582.1 725620 726819 D hypothetical protein 725620..726819 Streptococcus pneumoniae CGSP14 6218305 YP_001835452.1 CDS SPCG_0735 NC_010582.1 726803 727504 D ABC transporter ATP-binding protein 726803..727504 Streptococcus pneumoniae CGSP14 6218239 YP_001835453.1 CDS SPCG_0736 NC_010582.1 727506 728765 D hypothetical protein 727506..728765 Streptococcus pneumoniae CGSP14 6216348 YP_001835454.1 CDS metG NC_010582.1 728847 730886 D methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase 728847..730886 Streptococcus pneumoniae CGSP14 6218152 YP_001835455.1 CDS SPCG_0738 NC_010582.1 731259 731582 D hypothetical protein 731259..731582 Streptococcus pneumoniae CGSP14 6216715 YP_001835456.1 CDS SPCG_0739 NC_010582.1 731586 732401 D hypothetical protein 731586..732401 Streptococcus pneumoniae CGSP14 6218557 YP_001835457.1 CDS SPCG_0740 NC_010582.1 732473 733402 D aldo/keto reductase family oxidoreductase 732473..733402 Streptococcus pneumoniae CGSP14 6217484 YP_001835458.1 CDS SPCG_0741 NC_010582.1 733468 733734 D hypothetical protein 733468..733734 Streptococcus pneumoniae CGSP14 6217813 YP_001835459.1 CDS fabG NC_010582.1 733727 734425 D Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; 3-ketoacyl-ACP reductase 733727..734425 Streptococcus pneumoniae CGSP14 6218331 YP_001835460.1 CDS SPCG_0743 NC_010582.1 734436 734936 D mutT/nudix family protein 734436..734936 Streptococcus pneumoniae CGSP14 6218303 YP_001835461.1 CDS SPCG_0744 NC_010582.1 734911 735783 D PEP-utilizing enzyme family protein 734911..735783 Streptococcus pneumoniae CGSP14 6217013 YP_001835462.1 CDS SPCG_0745 NC_010582.1 735758 736198 D hypothetical protein 735758..736198 Streptococcus pneumoniae CGSP14 6218004 YP_001835463.1 CDS pepN NC_010582.1 736321 738867 D aminopeptidase N 736321..738867 Streptococcus pneumoniae CGSP14 6216490 YP_001835464.1 CDS ciaR NC_010582.1 738910 739650 D DNA-binding response regulator CiaR 738910..739650 Streptococcus pneumoniae CGSP14 6218247 YP_001835465.1 CDS ciaH NC_010582.1 739640 740974 D sensor histidine kinase CiaH 739640..740974 Streptococcus pneumoniae CGSP14 6218527 YP_001835466.1 CDS SPCG_0749 NC_010582.1 741008 741295 R hypothetical protein complement(741008..741295) Streptococcus pneumoniae CGSP14 6217006 YP_001835467.1 CDS SPCG_0750 NC_010582.1 741294 742364 D hypothetical protein 741294..742364 Streptococcus pneumoniae CGSP14 6216870 YP_001835468.1 CDS dinG NC_010582.1 742564 745014 D unwinds DNA; bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon 742564..745014 Streptococcus pneumoniae CGSP14 6216584 YP_001835469.1 CDS rodA NC_010582.1 745024 746274 D rod shape-determining protein RodA 745024..746274 Streptococcus pneumoniae CGSP14 6218420 YP_001835470.1 CDS thiJ NC_010582.1 746285 746839 D 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis protein 746285..746839 Streptococcus pneumoniae CGSP14 6216911 YP_001835471.1 CDS gph NC_010582.1 746915 747487 D HAD superfamily hydrolase 746915..747487 Streptococcus pneumoniae CGSP14 6217799 YP_001835472.1 CDS gyrB NC_010582.1 747502 749448 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit B 747502..749448 Streptococcus pneumoniae CGSP14 6216501 YP_001835473.1 CDS ezrA NC_010582.1 749503 751257 D acts to negatively regulates ftsZ ring formation by modulating the frequency and position of the ftsZ ring formation; septation ring formation regulator EzrA 749503..751257 Streptococcus pneumoniae CGSP14 6217584 YP_001835474.1 CDS SPCG_0757 NC_010582.1 751788 751883 D hypothetical protein 751788..751883 Streptococcus pneumoniae CGSP14 6216926 YP_001835475.1 CDS SPCG_0758 NC_010582.1 751981 752196 R IS66 family Orf2 complement(751981..752196) Streptococcus pneumoniae CGSP14 6216640 YP_001835476.1 CDS SPCG_0759 NC_010582.1 752564 752863 R hypothetical protein complement(752564..752863) Streptococcus pneumoniae CGSP14 6218423 YP_001835477.1 CDS SPCG_0760 NC_010582.1 753028 753492 R mutT/nudix family protein complement(753028..753492) Streptococcus pneumoniae CGSP14 6218584 YP_001835478.1 CDS SPCG_0761 NC_010582.1 753542 753958 D IS630-Spn1, transposase Orf1 753542..753958 Streptococcus pneumoniae CGSP14 6218294 YP_001835479.1 CDS clpE NC_010582.1 754612 756870 R ATP-dependent Clp protease, ATP-binding subunit ClpE complement(754612..756870) Streptococcus pneumoniae CGSP14 6217814 YP_001835480.1 CDS SPCG_0763 NC_010582.1 757099 757329 R hypothetical protein complement(757099..757329) Streptococcus pneumoniae CGSP14 6218237 YP_001835481.1 CDS SPCG_0764 NC_010582.1 757513 758202 D amino acid ABC transporter permease 757513..758202 Streptococcus pneumoniae CGSP14 6218145 YP_001835482.1 CDS SPCG_0765 NC_010582.1 758202 758936 D amino acid ABC transporter ATP-binding protein 758202..758936 Streptococcus pneumoniae CGSP14 6216922 YP_001835483.1 CDS SPCG_0766 NC_010582.1 759027 759947 D catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate; bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase 759027..759947 Streptococcus pneumoniae CGSP14 6217152 YP_001835484.1 CDS SPCG_0767 NC_010582.1 760085 760906 D hypothetical protein 760085..760906 Streptococcus pneumoniae CGSP14 6217945 YP_001835485.1 CDS SPCG_0768 NC_010582.1 760921 761793 D hypothetical protein 760921..761793 Streptococcus pneumoniae CGSP14 6217526 YP_001835486.1 CDS SPCG_0769 NC_010582.1 761790 761915 R hypothetical protein complement(761790..761915) Streptococcus pneumoniae CGSP14 6216738 YP_001835487.1 CDS rpiA NC_010582.1 762018 762758 D Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway; ribose-5-phosphate isomerase A 762018..762758 Streptococcus pneumoniae CGSP14 6217933 YP_001835488.1 CDS deoB NC_010582.1 762709 763983 D catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; phosphopentomutase 762709..763983 Streptococcus pneumoniae CGSP14 6216458 YP_001835489.1 CDS SPCG_0772 NC_010582.1 763985 764158 D hypothetical protein 763985..764158 Streptococcus pneumoniae CGSP14 6216589 YP_001835490.1 CDS SPCG_0773 NC_010582.1 764273 764542 D hypothetical protein 764273..764542 Streptococcus pneumoniae CGSP14 6216746 YP_001835491.1 CDS pnp NC_010582.1 764542 765351 D catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation; purine nucleoside phosphorylase 764542..765351 Streptococcus pneumoniae CGSP14 6217022 YP_001835492.1 CDS SPCG_0775 NC_010582.1 765815 766222 D hypothetical protein 765815..766222 Streptococcus pneumoniae CGSP14 6216700 YP_001835493.1 CDS SPCG_0776 NC_010582.1 766232 766807 D hypothetical protein 766232..766807 Streptococcus pneumoniae CGSP14 6217430 YP_001835494.1 CDS SPCG_0777 NC_010582.1 766832 767344 D hemolysin-like protein 766832..767344 Streptococcus pneumoniae CGSP14 6218330 YP_001835495.1 CDS deoD NC_010582.1 768002 768712 D catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate; purine nucleoside phosphorylase 768002..768712 Streptococcus pneumoniae CGSP14 6216751 YP_001835496.1 CDS flaR NC_010582.1 768735 769259 R topology modulation protein complement(768735..769259) Streptococcus pneumoniae CGSP14 6217973 YP_001835497.1 CDS rpsT NC_010582.1 769312 769563 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(769312..769563) Streptococcus pneumoniae CGSP14 6216796 YP_001835498.1 CDS coaA NC_010582.1 769616 770566 R catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis; pantothenate kinase complement(769616..770566) Streptococcus pneumoniae CGSP14 6217727 YP_001835499.1 CDS SPCG_0782 NC_010582.1 770726 771130 D hypothetical protein 770726..771130 Streptococcus pneumoniae CGSP14 6216587 YP_001835500.1 CDS SPCG_0783 NC_010582.1 771337 771927 D hypothetical protein 771337..771927 Streptococcus pneumoniae CGSP14 6218088 YP_001835501.1 CDS pdp NC_010582.1 771924 773201 D Catalyzes the reversible phosphorolysis of pyrimidines in the nucleotide synthesis salvage pathway; pyrimidine-nucleoside phosphorylase 771924..773201 Streptococcus pneumoniae CGSP14 6218084 YP_001835502.1 CDS deoC NC_010582.1 773219 773881 D catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate; deoxyribose-phosphate aldolase 773219..773881 Streptococcus pneumoniae CGSP14 6216427 YP_001835503.1 CDS cdd NC_010582.1 773868 774257 D Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; cytidine deaminase 773868..774257 Streptococcus pneumoniae CGSP14 6217976 YP_001835504.1 CDS SPCG_0787 NC_010582.1 774275 775399 D lipoprotein 774275..775399 Streptococcus pneumoniae CGSP14 6217774 YP_001835505.1 CDS SPCG_0788 NC_010582.1 775543 777078 D sugar ABC transporter ATP-binding protein 775543..777078 Streptococcus pneumoniae CGSP14 6217380 YP_001835506.1 CDS SPCG_0789 NC_010582.1 777044 778129 D sugar ABC transporter permease 777044..778129 Streptococcus pneumoniae CGSP14 6216533 YP_001835507.1 CDS SPCG_0790 NC_010582.1 778132 779088 D sugar ABC transporter permease 778132..779088 Streptococcus pneumoniae CGSP14 6217614 YP_001835508.1 CDS SPCG_0791 NC_010582.1 779173 779385 D degenerate transposase 779173..779385 Streptococcus pneumoniae CGSP14 6216873 YP_001835509.1 CDS SPCG_0792 NC_010582.1 779521 779688 D hypothetical protein 779521..779688 Streptococcus pneumoniae CGSP14 6217146 YP_001835510.1 CDS SPCG_0793 NC_010582.1 779688 779960 D degenerate transposase 779688..779960 Streptococcus pneumoniae CGSP14 6218345 YP_001835511.1 CDS SPCG_0794 NC_010582.1 780022 780510 D degenerate transposase 780022..780510 Streptococcus pneumoniae CGSP14 6216592 YP_001835512.1 CDS SPCG_0795 NC_010582.1 780553 781194 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX; glycerol-3-phosphate acyltransferase PlsY complement(780553..781194) Streptococcus pneumoniae CGSP14 6216890 YP_001835513.1 CDS parE NC_010582.1 781330 783273 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit B 781330..783273 Streptococcus pneumoniae CGSP14 6217743 YP_001835514.1 CDS SPCG_0797 NC_010582.1 783273 783380 D hypothetical protein 783273..783380 Streptococcus pneumoniae CGSP14 6218463 YP_001835515.1 CDS SPCG_0798 NC_010582.1 783394 783519 D hypothetical protein 783394..783519 Streptococcus pneumoniae CGSP14 6216352 YP_001835516.1 CDS parC NC_010582.1 783684 786164 D decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; DNA topoisomerase IV subunit A 783684..786164 Streptococcus pneumoniae CGSP14 6216634 YP_001835517.1 CDS ilvE NC_010582.1 786296 787318 D catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; branched-chain amino acid aminotransferase 786296..787318 Streptococcus pneumoniae CGSP14 6217796 YP_001835518.1 CDS SPCG_0801 NC_010582.1 787374 788078 D peptide ABC transporter periplasmic protein 787374..788078 Streptococcus pneumoniae CGSP14 6217323 YP_001835519.1 CDS SPCG_0802 NC_010582.1 788122 788832 D hypothetical protein 788122..788832 Streptococcus pneumoniae CGSP14 6216489 YP_001835520.1 CDS SPCG_0803 NC_010582.1 788829 789752 D membrane protein 788829..789752 Streptococcus pneumoniae CGSP14 6217151 YP_001835521.1 CDS pcp NC_010582.1 789767 790411 D catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase 789767..790411 Streptococcus pneumoniae CGSP14 6216696 YP_001835522.1 CDS SPCG_0805 NC_010582.1 790579 790809 D hypothetical protein 790579..790809 Streptococcus pneumoniae CGSP14 6218442 YP_001835523.1 CDS rpsA NC_010582.1 791182 792384 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 791182..792384 Streptococcus pneumoniae CGSP14 6216442 YP_001835524.1 CDS SPCG_0807 NC_010582.1 792469 792972 R degenerate transposase complement(792469..792972) Streptococcus pneumoniae CGSP14 6217287 YP_001835525.1 CDS SPCG_0808 NC_010582.1 793253 793624 R degenerate transposase complement(793253..793624) Streptococcus pneumoniae CGSP14 6217755 YP_001835526.1 CDS SPCG_0809 NC_010582.1 793964 794461 D hypothetical protein 793964..794461 Streptococcus pneumoniae CGSP14 6217103 YP_001835527.1 CDS dnaX NC_010582.1 794461 796116 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA; DNA polymerase III subunits gamma and tau 794461..796116 Streptococcus pneumoniae CGSP14 6217979 YP_001835528.1 CDS SPCG_0811 NC_010582.1 796144 796338 D hypothetical protein 796144..796338 Streptococcus pneumoniae CGSP14 6217620 YP_001835529.1 CDS SPCG_0812 NC_010582.1 796467 797258 D ABC transporter ATP-binding protein 796467..797258 Streptococcus pneumoniae CGSP14 6217663 YP_001835530.1 CDS SPCG_0813 NC_010582.1 797286 798548 D hypothetical protein 797286..798548 Streptococcus pneumoniae CGSP14 6218282 YP_001835531.1 CDS SPCG_0814 NC_010582.1 798514 799785 D class-V aminotransferase 798514..799785 Streptococcus pneumoniae CGSP14 6216536 YP_001835532.1 CDS nifU NC_010582.1 799742 800212 D nifU family protein 799742..800212 Streptococcus pneumoniae CGSP14 6216766 YP_001835533.1 CDS SPCG_0816 NC_010582.1 800266 801678 D FeS assembly protein SufB 800266..801678 Streptococcus pneumoniae CGSP14 6218313 YP_001835534.1 CDS dacA NC_010582.1 801909 803150 R D-alanyl-D-alanine carboxypeptidase complement(801909..803150) Streptococcus pneumoniae CGSP14 6218357 YP_001835535.1 CDS SPCG_0818 NC_010582.1 803253 804362 D membrane protein 803253..804362 Streptococcus pneumoniae CGSP14 6218334 YP_001835536.1 CDS SPCG_0819 NC_010582.1 805241 805348 R hypothetical protein complement(805241..805348) Streptococcus pneumoniae CGSP14 6218351 YP_001835537.1 CDS SPCG_0820 NC_010582.1 805487 806263 R hypothetical protein complement(805487..806263) Streptococcus pneumoniae CGSP14 6218133 YP_001835538.1 CDS SPCG_0821 NC_010582.1 806290 806760 R hypothetical protein complement(806290..806760) Streptococcus pneumoniae CGSP14 6217091 YP_001835539.1 CDS SPCG_0822 NC_010582.1 806815 807279 R hypothetical protein complement(806815..807279) Streptococcus pneumoniae CGSP14 6217084 YP_001835540.1 CDS SPCG_0823 NC_010582.1 807327 807434 D hypothetical protein 807327..807434 Streptococcus pneumoniae CGSP14 6218062 YP_001835541.1 CDS fruR NC_010582.1 807884 808624 D lactose phosphotransferase system repressor 807884..808624 Streptococcus pneumoniae CGSP14 6216732 YP_001835542.1 CDS fruB NC_010582.1 808621 809532 D 1-phosphofructokinase 808621..809532 Streptococcus pneumoniae CGSP14 6216550 YP_001835543.1 CDS fruA NC_010582.1 809529 811481 D PTS system fructose specific transporter subunit IIABC 809529..811481 Streptococcus pneumoniae CGSP14 6217632 YP_001835544.1 CDS ftsK NC_010582.1 811567 813870 D spoE family protein 811567..813870 Streptococcus pneumoniae CGSP14 6216770 YP_001835545.1 CDS SPCG_0828 NC_010582.1 813915 814448 R hypothetical protein complement(813915..814448) Streptococcus pneumoniae CGSP14 6216858 YP_001835546.1 CDS SPCG_0829 NC_010582.1 814421 815623 D class-V aminotransferase 814421..815623 Streptococcus pneumoniae CGSP14 6218109 YP_001835547.1 CDS thiI NC_010582.1 815632 816846 D Required for the synthesis of the thiazole moiety; thiamine biosynthesis protein ThiI 815632..816846 Streptococcus pneumoniae CGSP14 6218272 YP_001835548.1 CDS SPCG_0831 NC_010582.1 816957 817805 D hypothetical protein 816957..817805 Streptococcus pneumoniae CGSP14 6216623 YP_001835549.1 CDS SPCG_0832 NC_010582.1 817827 818162 D hypothetical protein 817827..818162 Streptococcus pneumoniae CGSP14 6217162 YP_001835550.1 CDS SPCG_0833 NC_010582.1 818159 818566 D hypothetical protein 818159..818566 Streptococcus pneumoniae CGSP14 6217378 YP_001835551.1 CDS SPCG_0834 NC_010582.1 818579 819745 D hypothetical protein 818579..819745 Streptococcus pneumoniae CGSP14 6218037 YP_001835552.1 CDS SPCG_0835 NC_010582.1 820253 821746 D type I restriction-modification system, M subunit 820253..821746 Streptococcus pneumoniae CGSP14 6216456 YP_001835553.1 CDS SPCG_0836 NC_010582.1 821759 822301 D type I restriction-modification system subunit S 821759..822301 Streptococcus pneumoniae CGSP14 6216388 YP_001835554.1 CDS SPCG_0837 NC_010582.1 822298 823416 D type I restriction-modification system subunit S 822298..823416 Streptococcus pneumoniae CGSP14 6217549 YP_001835555.1 CDS SPCG_0838 NC_010582.1 823476 823712 D hypothetical protein 823476..823712 Streptococcus pneumoniae CGSP14 6216614 YP_001835556.1 CDS SPCG_0839 NC_010582.1 823709 824122 D hypothetical protein 823709..824122 Streptococcus pneumoniae CGSP14 6216861 YP_001835557.1 CDS SPCG_0840 NC_010582.1 824240 825205 D phage integrase family integrase/recombinase 824240..825205 Streptococcus pneumoniae CGSP14 6217210 YP_001835558.1 CDS SPCG_0841 NC_010582.1 825150 825809 D type I restriction-modification system subunit S 825150..825809 Streptococcus pneumoniae CGSP14 6217053 YP_001835559.1 CDS SPCG_0842 NC_010582.1 825839 829189 D type I restriction-modification system, R subunit 825839..829189 Streptococcus pneumoniae CGSP14 6216644 YP_001835560.1 CDS SPCG_0843 NC_010582.1 829589 831169 R IS1380-Spn1 transposase complement(829589..831169) Streptococcus pneumoniae CGSP14 6216857 YP_001835561.1 CDS SPCG_0844 NC_010582.1 831169 831369 D hypothetical protein 831169..831369 Streptococcus pneumoniae CGSP14 6217080 YP_001835562.1 CDS SPCG_0845 NC_010582.1 831571 831846 R degenerate transposase complement(831571..831846) Streptococcus pneumoniae CGSP14 6217279 YP_001835563.1 CDS SPCG_0846 NC_010582.1 831902 832045 D hypothetical protein 831902..832045 Streptococcus pneumoniae CGSP14 6217150 YP_001835564.1 CDS SPCG_0847 NC_010582.1 832138 832725 D hypothetical protein 832138..832725 Streptococcus pneumoniae CGSP14 6218556 YP_001835565.1 CDS SPCG_0848 NC_010582.1 833123 833932 D phosphosugar-binding transcriptional regulator 833123..833932 Streptococcus pneumoniae CGSP14 6218366 YP_001835566.1 CDS SPCG_0849 NC_010582.1 833937 834638 D Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase 833937..834638 Streptococcus pneumoniae CGSP14 6217592 YP_001835567.1 CDS SPCG_0850 NC_010582.1 834663 835580 D N-acetylneuraminate lyase 834663..835580 Streptococcus pneumoniae CGSP14 6217271 YP_001835568.1 CDS SPCG_0851 NC_010582.1 835608 837149 D sodium:solute symporter family protein 835608..837149 Streptococcus pneumoniae CGSP14 6216650 YP_001835569.1 CDS SPCG_0852 NC_010582.1 837168 837626 D hypothetical protein 837168..837626 Streptococcus pneumoniae CGSP14 6216652 YP_001835570.1 CDS nanC NC_010582.1 837628 839850 D neuraminidase 837628..839850 Streptococcus pneumoniae CGSP14 6216534 YP_001835571.1 CDS SPCG_0854 NC_010582.1 839860 840999 D Gfo/Idh/MocA family oxidoreductase 839860..840999 Streptococcus pneumoniae CGSP14 6217504 YP_001835572.1 CDS SPCG_0855 NC_010582.1 841156 842046 D ROK family protein 841156..842046 Streptococcus pneumoniae CGSP14 6216931 YP_001835573.1 CDS SPCG_0856 NC_010582.1 842071 842394 D hypothetical protein 842071..842394 Streptococcus pneumoniae CGSP14 6217062 YP_001835574.1 CDS SPCG_0857 NC_010582.1 842384 844375 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit I is part of the membrane proton channel.; V-type ATP synthase subunit I 842384..844375 Streptococcus pneumoniae CGSP14 6218484 YP_001835575.1 CDS SPCG_0858 NC_010582.1 844391 844867 D produces ATP from ADP in the presence of a proton gradient across the membrane; the K subunit is a nonenzymatic component which binds the dimeric form by interacting with the G and E subunits; V-type ATP synthase subunit K 844391..844867 Streptococcus pneumoniae CGSP14 6217783 YP_001835576.1 CDS SPCG_0859 NC_010582.1 844901 845482 D v-type sodium ATP synthase subunit E 844901..845482 Streptococcus pneumoniae CGSP14 6217874 YP_001835577.1 CDS SPCG_0860 NC_010582.1 845547 846554 D v-type sodium ATP synthase subunit C 845547..846554 Streptococcus pneumoniae CGSP14 6216499 YP_001835578.1 CDS SPCG_0861 NC_010582.1 846544 846864 D produces ATP from ADP in the presence of a proton gradient across the membrane; the F subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit F 846544..846864 Streptococcus pneumoniae CGSP14 6217258 YP_001835579.1 CDS SPCG_0862 NC_010582.1 846903 848702 D produces ATP from ADP in the presence of a proton gradient across the membrane; the A subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit A 846903..848702 Streptococcus pneumoniae CGSP14 6218341 YP_001835580.1 CDS SPCG_0863 NC_010582.1 848703 850088 D produces ATP from ADP in the presence of a proton gradient across the membrane; the B subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit B 848703..850088 Streptococcus pneumoniae CGSP14 6217447 YP_001835581.1 CDS SPCG_0864 NC_010582.1 850111 850722 D produces ATP from ADP in the presence of a proton gradient across the membrane; the D subunit is part of the catalytic core of the ATP synthase complex; V-type ATP synthase subunit D 850111..850722 Streptococcus pneumoniae CGSP14 6217215 YP_001835582.1 CDS SPCG_0865 NC_010582.1 850832 851359 R degenerate transposase complement(850832..851359) Streptococcus pneumoniae CGSP14 6217244 YP_001835583.1 CDS SPCG_0866 NC_010582.1 851640 852158 R degenerate transposase complement(851640..852158) Streptococcus pneumoniae CGSP14 6218310 YP_001835584.1 CDS SPCG_0867 NC_010582.1 852291 852458 D hypothetical protein 852291..852458 Streptococcus pneumoniae CGSP14 6218388 YP_001835585.1 CDS SPCG_0868 NC_010582.1 852474 852734 D hypothetical protein 852474..852734 Streptococcus pneumoniae CGSP14 6217111 YP_001835586.1 CDS SPCG_0869 NC_010582.1 852838 853308 R transcriptional repressor complement(852838..853308) Streptococcus pneumoniae CGSP14 6218325 YP_001835587.1 CDS SPCG_0870 NC_010582.1 853325 855598 R catalyzes the removal of N-terminal dipeptides when proline is the penultimate residue; x-prolyl-dipeptidyl aminopeptidase complement(853325..855598) Streptococcus pneumoniae CGSP14 6217579 YP_001835588.1 CDS dnaE NC_010582.1 855918 859046 D Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. Proposed to be responsible for the synthesis of the lagging strand. In the low GC gram positive bacteria this enzyme is less processive and more error prone than its counterpart in other bacteria.; DNA polymerase III DnaE 855918..859046 Streptococcus pneumoniae CGSP14 6218323 YP_001835589.1 CDS pfkA NC_010582.1 859129 860136 D catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis; 6-phosphofructokinase 859129..860136 Streptococcus pneumoniae CGSP14 6218307 YP_001835590.1 CDS SPCG_0873 NC_010582.1 860195 861700 D catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate kinase 860195..861700 Streptococcus pneumoniae CGSP14 6218444 YP_001835591.1 CDS SPCG_0874 NC_010582.1 862864 863082 R hypothetical protein complement(862864..863082) Streptococcus pneumoniae CGSP14 6218324 YP_001835592.1 CDS SPCG_0875 NC_010582.1 863518 864390 D hypothetical protein 863518..864390 Streptococcus pneumoniae CGSP14 6218289 YP_001835593.1 CDS SPCG_0876 NC_010582.1 864403 864567 D hypothetical protein 864403..864567 Streptococcus pneumoniae CGSP14 6216726 YP_001835594.1 CDS SPCG_0877 NC_010582.1 864488 864580 D hypothetical protein 864488..864580 Streptococcus pneumoniae CGSP14 6218349 YP_001835595.1 CDS SPCG_0878 NC_010582.1 864497 864880 R IS1381 transposase protein A complement(864497..864880) Streptococcus pneumoniae CGSP14 6217070 YP_001835596.1 CDS SPCG_0879 NC_010582.1 865023 865334 D hypothetical protein 865023..865334 Streptococcus pneumoniae CGSP14 6217335 YP_001835597.1 CDS SPCG_0880 NC_010582.1 865338 866054 D hypothetical protein 865338..866054 Streptococcus pneumoniae CGSP14 6217114 YP_001835598.1 CDS SPCG_0881 NC_010582.1 866184 866999 R hypothetical protein complement(866184..866999) Streptococcus pneumoniae CGSP14 6216756 YP_001835599.1 CDS SPCG_0882 NC_010582.1 866996 867901 R hypothetical protein complement(866996..867901) Streptococcus pneumoniae CGSP14 6216908 YP_001835600.1 CDS SPCG_0883 NC_010582.1 867902 868033 R hypothetical protein complement(867902..868033) Streptococcus pneumoniae CGSP14 6217596 YP_001835601.1 CDS SPCG_0884 NC_010582.1 868243 869610 D capsular polysaccharide biosynthesis protein 868243..869610 Streptococcus pneumoniae CGSP14 6217379 YP_001835602.1 CDS SPCG_0885 NC_010582.1 869694 871841 D transcriptional regulator 869694..871841 Streptococcus pneumoniae CGSP14 6218091 YP_001835603.1 CDS SPCG_0886 NC_010582.1 871828 872277 D hypothetical protein 871828..872277 Streptococcus pneumoniae CGSP14 6216511 YP_001835604.1 CDS SPCG_0887 NC_010582.1 872335 872607 D hypothetical protein 872335..872607 Streptococcus pneumoniae CGSP14 6218103 YP_001835605.1 CDS SPCG_0888 NC_010582.1 872655 872819 R hypothetical protein complement(872655..872819) Streptococcus pneumoniae CGSP14 6217934 YP_001835606.1 CDS SPCG_0889 NC_010582.1 873523 874338 D ABC transporter ATP-binding protein 873523..874338 Streptococcus pneumoniae CGSP14 6218270 YP_001835607.1 CDS SPCG_0890 NC_010582.1 874340 876328 D ABC transporter permease 874340..876328 Streptococcus pneumoniae CGSP14 6216523 YP_001835608.1 CDS SPCG_0891 NC_010582.1 876370 876960 R membrane protein complement(876370..876960) Streptococcus pneumoniae CGSP14 6216524 YP_001835609.1 CDS SPCG_0892 NC_010582.1 877040 877960 R IS1239 transposase complement(877040..877960) Streptococcus pneumoniae CGSP14 6218368 YP_001835610.1 CDS cad NC_010582.1 878622 880097 D lysine decarboxylase 878622..880097 Streptococcus pneumoniae CGSP14 6218353 YP_001835611.1 CDS SPCG_0894 NC_010582.1 880063 880533 R pilin gene inverting-like protein,truncated complement(880063..880533) Streptococcus pneumoniae CGSP14 6218342 YP_001835612.1 CDS speE NC_010582.1 881034 881894 D catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine; spermidine synthase 881034..881894 Streptococcus pneumoniae CGSP14 6217110 YP_001835613.1 CDS SPCG_0896 NC_010582.1 881891 883150 D hypothetical protein 881891..883150 Streptococcus pneumoniae CGSP14 6218309 YP_001835614.1 CDS nspC NC_010582.1 883150 884277 D carboxynorspermidine decarboxylase 883150..884277 Streptococcus pneumoniae CGSP14 6218538 YP_001835615.1 CDS SPCG_0898 NC_010582.1 884274 885359 D catalyzes the formation of carbamoylputrescine from agmatine in the arginine decarboxylase pathway of putrescine biosynthesis; agmatine deiminase 884274..885359 Streptococcus pneumoniae CGSP14 6218316 YP_001835616.1 CDS SPCG_0899 NC_010582.1 885369 886244 D carbon-nitrogen hydrolase family protein 885369..886244 Streptococcus pneumoniae CGSP14 6218315 YP_001835617.1 CDS SPCG_0900 NC_010582.1 886425 887234 R Cof family protein complement(886425..887234) Streptococcus pneumoniae CGSP14 6217633 YP_001835618.1 CDS SPCG_0901 NC_010582.1 887781 888452 D hypothetical protein 887781..888452 Streptococcus pneumoniae CGSP14 6216526 YP_001835619.1 CDS cpsY NC_010582.1 888694 889602 D LysR family transcriptional regulator 888694..889602 Streptococcus pneumoniae CGSP14 6217400 YP_001835620.1 CDS lspA NC_010582.1 889599 890060 D lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 889599..890060 Streptococcus pneumoniae CGSP14 6218545 YP_001835621.1 CDS rluD NC_010582.1 890050 890937 D ribosomal large subunit pseudouridine synthase D 890050..890937 Streptococcus pneumoniae CGSP14 6216935 YP_001835622.1 CDS lytD NC_010582.1 890940 892823 D choline binding protein E 890940..892823 Streptococcus pneumoniae CGSP14 6217197 YP_001835623.1 CDS proB NC_010582.1 892903 894033 D catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis; gamma-glutamyl kinase 892903..894033 Streptococcus pneumoniae CGSP14 6218518 YP_001835624.1 CDS proA NC_010582.1 894043 895305 D Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway; gamma-glutamyl phosphate reductase 894043..895305 Streptococcus pneumoniae CGSP14 6216938 YP_001835625.1 CDS proC NC_010582.1 895309 896106 D pyrroline-5-carboxylate reductase 895309..896106 Streptococcus pneumoniae CGSP14 6218490 YP_001835626.1 CDS tmk NC_010582.1 896326 896964 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 896326..896964 Streptococcus pneumoniae CGSP14 6217554 YP_001835627.1 CDS holB NC_010582.1 896961 897851 D catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA.; DNA polymerase III subunit delta' 896961..897851 Streptococcus pneumoniae CGSP14 6216527 YP_001835628.1 CDS SPCG_0911 NC_010582.1 897864 898208 D in Bacillus subtilis this protein is involved in the negative regulation of DNA replication initiation; interacts with DnaN and DnaA; DNA replication intiation control protein YabA 897864..898208 Streptococcus pneumoniae CGSP14 6217342 YP_001835629.1 CDS SPCG_0912 NC_010582.1 898211 899080 D tetrapyrrole methylase family protein 898211..899080 Streptococcus pneumoniae CGSP14 6218269 YP_001835630.1 CDS SPCG_0913 NC_010582.1 899280 899825 D hypothetical protein 899280..899825 Streptococcus pneumoniae CGSP14 6217105 YP_001835631.1 CDS SPCG_0914 NC_010582.1 900078 900512 D hypothetical protein 900078..900512 Streptococcus pneumoniae CGSP14 6217355 YP_001835632.1 CDS SPCG_0915 NC_010582.1 900570 900959 R IS1381 transposase protein B complement(900570..900959) Streptococcus pneumoniae CGSP14 6217634 YP_001835633.1 CDS SPCG_0916 NC_010582.1 900976 901377 R IS1381 transposase protein A complement(900976..901377) Streptococcus pneumoniae CGSP14 6217702 YP_001835634.1 CDS gidA NC_010582.1 901748 903154 D TrmFO; Gid; glucose-inhibited division protein; similar to GidA; the gene from Bacillus subtilis encodes a tRNA-methyltransferase that utilizes folate as the carbon donor and bound flavin as reductant; modifies tRNA at position 54 (uridine) of the T-psi loop to form a C5-methyluridine; tRNA (uracil-5-)-methyltransferase Gid 901748..903154 Streptococcus pneumoniae CGSP14 6218045 YP_001835635.1 CDS pyrH NC_010582.1 903232 903975 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 903232..903975 Streptococcus pneumoniae CGSP14 6218181 YP_001835636.1 CDS frr NC_010582.1 903984 904541 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 903984..904541 Streptococcus pneumoniae CGSP14 6216543 YP_001835637.1 CDS SPCG_0920 NC_010582.1 904562 905455 D hypothetical protein 904562..905455 Streptococcus pneumoniae CGSP14 6218158 YP_001835638.1 CDS SPCG_0921 NC_010582.1 905464 905679 D hypothetical protein 905464..905679 Streptococcus pneumoniae CGSP14 6216765 YP_001835639.1 CDS phoL NC_010582.1 905765 906733 D phoH family protein 905765..906733 Streptococcus pneumoniae CGSP14 6216768 YP_001835640.1 CDS SPCG_0923 NC_010582.1 906736 907203 D hypothetical protein 906736..907203 Streptococcus pneumoniae CGSP14 6216598 YP_001835641.1 CDS SPCG_0924 NC_010582.1 907215 907592 D hypothetical protein 907215..907592 Streptococcus pneumoniae CGSP14 6217371 YP_001835642.1 CDS SPCG_0925 NC_010582.1 907775 908275 D acetyltransferase 907775..908275 Streptococcus pneumoniae CGSP14 6218449 YP_001835643.1 CDS SPCG_0926 NC_010582.1 908278 908505 D hypothetical protein 908278..908505 Streptococcus pneumoniae CGSP14 6217325 YP_001835644.1 CDS SPCG_0927 NC_010582.1 908909 909184 R alanine dehydrogenase complement(908909..909184) Streptococcus pneumoniae CGSP14 6217237 YP_001835645.1 CDS SPCG_0928 NC_010582.1 909181 910008 R alanine dehydrogenase complement(909181..910008) Streptococcus pneumoniae CGSP14 6216535 YP_001835646.1 CDS SPCG_0929 NC_010582.1 910185 910754 D acetyltransferase 910185..910754 Streptococcus pneumoniae CGSP14 6217158 YP_001835647.1 CDS celA NC_010582.1 910822 911472 D competence protein CelA 910822..911472 Streptococcus pneumoniae CGSP14 6217719 YP_001835648.1 CDS celB NC_010582.1 911456 913696 D competence protein CelB 911456..913696 Streptococcus pneumoniae CGSP14 6218428 YP_001835649.1 CDS SPCG_0932 NC_010582.1 913875 914063 D hypothetical protein 913875..914063 Streptococcus pneumoniae CGSP14 6217741 YP_001835650.1 CDS SPCG_0933 NC_010582.1 914096 914623 D ABC transporter ATP-binding protein 914096..914623 Streptococcus pneumoniae CGSP14 6218384 YP_001835651.1 CDS SPCG_0934 NC_010582.1 914679 915863 D hypothetical protein 914679..915863 Streptococcus pneumoniae CGSP14 6218409 YP_001835652.1 CDS infC NC_010582.1 916117 916704 D IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits; translation initiation factor IF-3 916117..916704 Streptococcus pneumoniae CGSP14 6218320 YP_001835653.1 CDS rpmI NC_010582.1 916737 916937 D 50S ribosomal protein L35 916737..916937 Streptococcus pneumoniae CGSP14 6217039 YP_001835654.1 CDS rplT NC_010582.1 916989 917348 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 916989..917348 Streptococcus pneumoniae CGSP14 6218214 YP_001835655.1 CDS lguL NC_010582.1 917355 917786 D lactoylglutathione lyase 917355..917786 Streptococcus pneumoniae CGSP14 6216892 YP_001835656.1 CDS pyrDII NC_010582.1 918036 918836 D responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+); dihydroorotate dehydrogenase electron transfer subunit 918036..918836 Streptococcus pneumoniae CGSP14 6217462 YP_001835657.1 CDS pyrD NC_010582.1 918793 919785 D catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway, using a flavin nucleotide as an essential cofactor; subclass 1B is a heterotetramer consisting of two PyrDB subunits, similar to the PyrDA subunits and two PyrK subunits; dihydroorotate dehydrogenase 1B 918793..919785 Streptococcus pneumoniae CGSP14 6216854 YP_001835658.1 CDS lytB NC_010582.1 919827 921860 D endo-beta-N-acetylglucosaminidase 919827..921860 Streptococcus pneumoniae CGSP14 6218274 YP_001835659.1 CDS flpA NC_010582.1 921921 923603 R adherence and virulence protein A complement(921921..923603) Streptococcus pneumoniae CGSP14 6218453 YP_001835660.1 CDS SPCG_0943 NC_010582.1 923681 924178 D metalloprotease 923681..924178 Streptococcus pneumoniae CGSP14 6218348 YP_001835661.1 CDS dgkA NC_010582.1 924159 924554 D diacylglycerol kinase 924159..924554 Streptococcus pneumoniae CGSP14 6218278 YP_001835662.1 CDS era NC_010582.1 924571 925470 D Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 924571..925470 Streptococcus pneumoniae CGSP14 6218123 YP_001835663.1 CDS mutM NC_010582.1 925519 926343 D Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases; formamidopyrimidine-DNA glycosylase 925519..926343 Streptococcus pneumoniae CGSP14 6218403 YP_001835664.1 CDS coaE NC_010582.1 926316 926948 D catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis; dephospho-CoA kinase 926316..926948 Streptococcus pneumoniae CGSP14 6218473 YP_001835665.1 CDS pmrA NC_010582.1 926935 928134 D multi-drug resistance efflux pump 926935..928134 Streptococcus pneumoniae CGSP14 6218585 YP_001835666.1 CDS secG NC_010582.1 928323 928556 D preprotein translocase subunit SecG 928323..928556 Streptococcus pneumoniae CGSP14 6218548 YP_001835667.1 CDS rnr NC_010582.1 928658 931012 D VacB/Rnb family exoribonuclease 928658..931012 Streptococcus pneumoniae CGSP14 6218561 YP_001835668.1 CDS smpB NC_010582.1 930975 931442 D binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 930975..931442 Streptococcus pneumoniae CGSP14 6218394 YP_001835669.1 CDS tehB NC_010582.1 931452 932318 D with TehA confers resistance to tellurite; tellurite resistance protein TehB 931452..932318 Streptococcus pneumoniae CGSP14 6218573 YP_001835670.1 CDS coiA NC_010582.1 932391 933344 D competence protein CoiA 932391..933344 Streptococcus pneumoniae CGSP14 6218259 YP_001835671.1 CDS SPCG_0954 NC_010582.1 933363 935165 D oligoendopeptidase F 933363..935165 Streptococcus pneumoniae CGSP14 6217348 YP_001835672.1 CDS SPCG_0955 NC_010582.1 935167 935880 D O-methyltransferase 935167..935880 Streptococcus pneumoniae CGSP14 6217098 YP_001835673.1 CDS prsA NC_010582.1 935947 936888 D cis/trans isomerase of peptidylprolyl; PPIase; membrane-bound lipoprotein; foldase protein PrsA 935947..936888 Streptococcus pneumoniae CGSP14 6217092 YP_001835674.1 CDS SPCG_0957 NC_010582.1 937007 937348 R IS3-Spn1, transposase, truncation complement(937007..937348) Streptococcus pneumoniae CGSP14 6218395 YP_001835675.1 CDS gpmB NC_010582.1 938109 938729 R phosphoglycerate mutase family protein complement(938109..938729) Streptococcus pneumoniae CGSP14 6218485 YP_001835676.1 CDS ebsC NC_010582.1 938729 939211 R regulatory protein complement(938729..939211) Streptococcus pneumoniae CGSP14 6218138 YP_001835677.1 CDS SPCG_0960 NC_010582.1 939211 940053 R hypothetical protein complement(939211..940053) Streptococcus pneumoniae CGSP14 6217787 YP_001835678.1 CDS SPCG_0961 NC_010582.1 940148 940948 R hypothetical protein complement(940148..940948) Streptococcus pneumoniae CGSP14 6217685 YP_001835679.1 CDS glmU NC_010582.1 941032 942471 D forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis; bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase 941032..942471 Streptococcus pneumoniae CGSP14 6218216 YP_001835680.1 CDS SPCG_0963 NC_010582.1 942481 943026 D mutT/nudix family protein 942481..943026 Streptococcus pneumoniae CGSP14 6217640 YP_001835681.1 CDS SPCG_0964 NC_010582.1 943005 943352 D hypothetical protein 943005..943352 Streptococcus pneumoniae CGSP14 6216839 YP_001835682.1 CDS pfs NC_010582.1 943369 944061 D enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine; 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 943369..944061 Streptococcus pneumoniae CGSP14 6216755 YP_001835683.1 CDS SPCG_0966 NC_010582.1 944138 944629 D hypothetical protein 944138..944629 Streptococcus pneumoniae CGSP14 6216989 YP_001835684.1 CDS dnaQ NC_010582.1 944691 945317 D 3'-5' exonuclease of DNA polymerase III; DNA polymerase III subunit epsilon 944691..945317 Streptococcus pneumoniae CGSP14 6217239 YP_001835685.1 CDS SPCG_0968 NC_010582.1 945320 947089 D hypothetical protein 945320..947089 Streptococcus pneumoniae CGSP14 6217015 YP_001835686.1 CDS SPCG_0969 NC_010582.1 947285 947632 D IS630-Spn1 transposase 947285..947632 Streptococcus pneumoniae CGSP14 6216627 YP_001835687.1 CDS SPCG_0970 NC_010582.1 947811 947951 D hypothetical protein 947811..947951 Streptococcus pneumoniae CGSP14 6218280 YP_001835688.1 CDS SPCG_0971 NC_010582.1 948112 948312 D hypothetical protein 948112..948312 Streptococcus pneumoniae CGSP14 6218279 YP_001835689.1 CDS SPCG_0972 NC_010582.1 948131 948763 R hypothetical protein complement(948131..948763) Streptococcus pneumoniae CGSP14 6218268 YP_001835690.1 CDS ccdA NC_010582.1 948989 949696 D cytochrome c-type biogenesis protein CcdA 948989..949696 Streptococcus pneumoniae CGSP14 6217305 YP_001835691.1 CDS SPCG_0974 NC_010582.1 949689 950264 D thioredoxin 949689..950264 Streptococcus pneumoniae CGSP14 6218558 YP_001835692.1 CDS yfnA NC_010582.1 950626 952029 D amino acid permease family protein 950626..952029 Streptococcus pneumoniae CGSP14 6216653 YP_001835693.1 CDS lmb NC_010582.1 952154 953089 D adhesion lipoprotein 952154..953089 Streptococcus pneumoniae CGSP14 6216674 YP_001835694.1 CDS SPCG_0977 NC_010582.1 953097 955601 D hypothetical protein 953097..955601 Streptococcus pneumoniae CGSP14 6218515 YP_001835695.1 CDS SPCG_0978 NC_010582.1 955811 958930 D hypothetical protein 955811..958930 Streptococcus pneumoniae CGSP14 6216834 YP_001835696.1 CDS SPCG_0979 NC_010582.1 959760 959900 D hypothetical protein 959760..959900 Streptococcus pneumoniae CGSP14 6217247 YP_001835697.1 CDS SPCG_0980 NC_010582.1 959934 960416 D histidine triad protein E , truncation 959934..960416 Streptococcus pneumoniae CGSP14 6217008 YP_001835698.1 CDS SPCG_0981 NC_010582.1 960525 960746 R hypothetical protein complement(960525..960746) Streptococcus pneumoniae CGSP14 6216874 YP_001835699.1 CDS SPCG_0982 NC_010582.1 960732 960968 D hypothetical protein 960732..960968 Streptococcus pneumoniae CGSP14 6216960 YP_001835700.1 CDS SPCG_0983 NC_010582.1 960997 961329 D hypothetical protein 960997..961329 Streptococcus pneumoniae CGSP14 6216666 YP_001835701.1 CDS pepT NC_010582.1 961365 962588 R catalyzes the release of the N-terminal amino acid from a tripeptide; peptidase T complement(961365..962588) Streptococcus pneumoniae CGSP14 6217920 YP_001835702.1 CDS hemH NC_010582.1 962743 963837 D ferrochelatase 962743..963837 Streptococcus pneumoniae CGSP14 6218249 YP_001835703.1 CDS SPCG_0986 NC_010582.1 963884 963976 R hypothetical protein complement(963884..963976) Streptococcus pneumoniae CGSP14 6216418 YP_001835704.1 CDS SPCG_0987 NC_010582.1 963992 964744 R degenerate transposase complement(963992..964744) Streptococcus pneumoniae CGSP14 6216440 YP_001835705.1 CDS SPCG_0988 NC_010582.1 964737 965282 R degenerate transposase complement(964737..965282) Streptococcus pneumoniae CGSP14 6218483 YP_001835706.1 CDS mscL NC_010582.1 965398 965775 R large conductance mechanosensitive channel protein MscL complement(965398..965775) Streptococcus pneumoniae CGSP14 6216326 YP_001835707.1 CDS SPCG_0990 NC_010582.1 965857 966288 R gtrA family protein complement(965857..966288) Streptococcus pneumoniae CGSP14 6217453 YP_001835708.1 CDS SPCG_0991 NC_010582.1 966339 966920 D hypothetical protein 966339..966920 Streptococcus pneumoniae CGSP14 6217929 YP_001835709.1 CDS SPCG_0992 NC_010582.1 967198 967452 D hypothetical protein 967198..967452 Streptococcus pneumoniae CGSP14 6218095 YP_001835710.1 CDS asd NC_010582.1 967678 968754 D catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde; aspartate-semialdehyde dehydrogenase 967678..968754 Streptococcus pneumoniae CGSP14 6218079 YP_001835711.1 CDS dapA NC_010582.1 968810 969745 D catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 968810..969745 Streptococcus pneumoniae CGSP14 6218321 YP_001835712.1 CDS trmE NC_010582.1 969792 971231 R in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE complement(969792..971231) Streptococcus pneumoniae CGSP14 6218380 YP_001835713.1 CDS xylH NC_010582.1 971302 971526 R 4-OT; member of subfamily 5; forms a dimer; the function in the Escherichia coli cell is unknown; 4-oxalocrotonate tautomerase complement(971302..971526) Streptococcus pneumoniae CGSP14 6218540 YP_001835714.1 CDS tdk NC_010582.1 971607 972197 D catalyzes the formation of thymidine 5'-phosphate from thymidine; thymidine kinase 971607..972197 Streptococcus pneumoniae CGSP14 6217129 YP_001835715.1 CDS prfA NC_010582.1 972194 973273 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 972194..973273 Streptococcus pneumoniae CGSP14 6217245 YP_001835716.1 CDS hemK NC_010582.1 973273 974112 D hemK protein 973273..974112 Streptococcus pneumoniae CGSP14 6218311 YP_001835717.1 CDS SPCG_1000 NC_010582.1 974069 974698 D Sua5/YciO/YrdC family protein 974069..974698 Streptococcus pneumoniae CGSP14 6218390 YP_001835718.1 CDS SPCG_1001 NC_010582.1 974661 975131 D acetyltransferase 974661..975131 Streptococcus pneumoniae CGSP14 6217779 YP_001835719.1 CDS glyA NC_010582.1 975193 976449 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 975193..976449 Streptococcus pneumoniae CGSP14 6217457 YP_001835720.1 CDS SPCG_1003 NC_010582.1 976424 977431 D hypothetical protein 976424..977431 Streptococcus pneumoniae CGSP14 6217200 YP_001835721.1 CDS SPCG_1004 NC_010582.1 977431 978045 D hypothetical protein 977431..978045 Streptococcus pneumoniae CGSP14 6217028 YP_001835722.1 CDS SPCG_1005 NC_010582.1 978119 979093 D hypothetical protein 978119..979093 Streptococcus pneumoniae CGSP14 6216987 YP_001835723.1 CDS SPCG_1006 NC_010582.1 979062 979154 D hypothetical protein 979062..979154 Streptococcus pneumoniae CGSP14 6216819 YP_001835724.1 CDS SPCG_1007 NC_010582.1 979167 980792 D RNA methyltransferase 979167..980792 Streptococcus pneumoniae CGSP14 6216782 YP_001835725.1 CDS SPCG_1008 NC_010582.1 981918 982019 D hypothetical protein 981918..982019 Streptococcus pneumoniae CGSP14 6216553 YP_001835726.1 CDS SPCG_1009 NC_010582.1 982140 983165 D iron-compound ABC transporter iron compound-binding protein 982140..983165 Streptococcus pneumoniae CGSP14 6216605 YP_001835727.1 CDS SPCG_1010 NC_010582.1 983136 983690 R hypothetical protein complement(983136..983690) Streptococcus pneumoniae CGSP14 6216875 YP_001835728.1 CDS SPCG_1011 NC_010582.1 983143 984162 D iron-compound ABC transporter permease 983143..984162 Streptococcus pneumoniae CGSP14 6218523 YP_001835729.1 CDS SPCG_1012 NC_010582.1 984162 985169 D iron-compound ABC transporter permease 984162..985169 Streptococcus pneumoniae CGSP14 6218200 YP_001835730.1 CDS SPCG_1013 NC_010582.1 985169 985963 D iron-compound ABC transporter ATP-binding protein 985169..985963 Streptococcus pneumoniae CGSP14 6218046 YP_001835731.1 CDS SPCG_1014 NC_010582.1 986832 987149 D hypothetical protein 986832..987149 Streptococcus pneumoniae CGSP14 6216659 YP_001835732.1 CDS SPCG_1015 NC_010582.1 987454 988167 D hypothetical protein 987454..988167 Streptococcus pneumoniae CGSP14 6217763 YP_001835733.1 CDS SPCG_1016 NC_010582.1 988185 989102 D hypothetical protein 988185..989102 Streptococcus pneumoniae CGSP14 6218318 YP_001835734.1 CDS SPCG_1017 NC_010582.1 989535 989939 D hypothetical protein 989535..989939 Streptococcus pneumoniae CGSP14 6218267 YP_001835735.1 CDS SPCG_1018 NC_010582.1 990113 990841 D phage-associated protein 990113..990841 Streptococcus pneumoniae CGSP14 6218206 YP_001835736.1 CDS SPCG_1019 NC_010582.1 991525 991686 D hypothetical protein 991525..991686 Streptococcus pneumoniae CGSP14 6217992 YP_001835737.1 CDS SPCG_1020 NC_010582.1 991778 993457 D resolvase family site-specific recombinase 991778..993457 Streptococcus pneumoniae CGSP14 6217811 YP_001835738.1 CDS SPCG_1021 NC_010582.1 993680 994291 D hypothetical protein 993680..994291 Streptococcus pneumoniae CGSP14 6218164 YP_001835739.1 CDS SPCG_1022 NC_010582.1 994604 994801 D hypothetical protein 994604..994801 Streptococcus pneumoniae CGSP14 6218113 YP_001835740.1 CDS SPCG_1023 NC_010582.1 994863 995621 D hypothetical protein 994863..995621 Streptococcus pneumoniae CGSP14 6217822 YP_001835741.1 CDS SPCG_1024 NC_010582.1 995679 996533 D hydrolase 995679..996533 Streptococcus pneumoniae CGSP14 6217844 YP_001835742.1 CDS SPCG_1025 NC_010582.1 996594 997529 D hypothetical protein 996594..997529 Streptococcus pneumoniae CGSP14 6216692 YP_001835743.1 CDS nplT NC_010582.1 997668 999431 D neopullulanase 997668..999431 Streptococcus pneumoniae CGSP14 6218118 YP_001835744.1 CDS SPCG_1027 NC_010582.1 999517 999834 D hypothetical protein 999517..999834 Streptococcus pneumoniae CGSP14 6216956 YP_001835745.1 CDS SPCG_1028 NC_010582.1 999880 1000161 D hypothetical protein 999880..1000161 Streptococcus pneumoniae CGSP14 6216958 YP_001835746.1 CDS SPCG_1029 NC_010582.1 1000549 1001082 D transcriptional regulator 1000549..1001082 Streptococcus pneumoniae CGSP14 6217113 YP_001835747.1 CDS SPCG_1030 NC_010582.1 1001082 1001843 D hypothetical protein 1001082..1001843 Streptococcus pneumoniae CGSP14 6217500 YP_001835748.1 CDS SPCG_1031 NC_010582.1 1001871 1002647 D phosphoesterase 1001871..1002647 Streptococcus pneumoniae CGSP14 6217845 YP_001835749.1 CDS SPCG_1032 NC_010582.1 1002650 1003027 D hypothetical protein 1002650..1003027 Streptococcus pneumoniae CGSP14 6217837 YP_001835750.1 CDS SPCG_1033 NC_010582.1 1003859 1004218 D Tn5252, ORF 10 protein 1003859..1004218 Streptococcus pneumoniae CGSP14 6218168 YP_001835751.1 CDS SPCG_1034 NC_010582.1 1004228 1004593 D Tn5252, ORF 9 protein 1004228..1004593 Streptococcus pneumoniae CGSP14 6217392 YP_001835752.1 CDS SPCG_1035 NC_010582.1 1004580 1006430 D Tn5252, relaxase 1004580..1006430 Streptococcus pneumoniae CGSP14 6217434 YP_001835753.1 CDS SPCG_1036 NC_010582.1 1006683 1007363 D degenerate transposase 1006683..1007363 Streptococcus pneumoniae CGSP14 6217716 YP_001835754.1 CDS SPCG_1037 NC_010582.1 1007381 1007650 D degenerate transposase 1007381..1007650 Streptococcus pneumoniae CGSP14 6217736 YP_001835755.1 CDS SPCG_1038 NC_010582.1 1008811 1009809 R IS1239 transposase complement(1008811..1009809) Streptococcus pneumoniae CGSP14 6218546 YP_001835756.1 CDS SPCG_1039 NC_010582.1 1010368 1011411 D hypothetical protein 1010368..1011411 Streptococcus pneumoniae CGSP14 6217452 YP_001835757.1 CDS topA NC_010582.1 1011560 1013665 D catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity; DNA topoisomerase I 1011560..1013665 Streptococcus pneumoniae CGSP14 6217713 YP_001835758.1 CDS SPCG_1041 NC_010582.1 1013886 1014245 D hypothetical protein 1013886..1014245 Streptococcus pneumoniae CGSP14 6216575 YP_001835759.1 CDS cutC NC_010582.1 1014338 1014970 D copper homeostasis protein CutC 1014338..1014970 Streptococcus pneumoniae CGSP14 6217242 YP_001835760.1 CDS SPCG_1043 NC_010582.1 1015014 1015670 D hypothetical protein 1015014..1015670 Streptococcus pneumoniae CGSP14 6217156 YP_001835761.1 CDS SPCG_1044 NC_010582.1 1015689 1016222 D hypothetical protein 1015689..1016222 Streptococcus pneumoniae CGSP14 6217573 YP_001835762.1 CDS SPCG_1045 NC_010582.1 1016338 1016772 D hypothetical protein 1016338..1016772 Streptococcus pneumoniae CGSP14 6216629 YP_001835763.1 CDS SPCG_1046 NC_010582.1 1016784 1017821 D catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis; 3-isopropylmalate dehydrogenase 1016784..1017821 Streptococcus pneumoniae CGSP14 6216740 YP_001835764.1 CDS SPCG_1047 NC_010582.1 1017818 1018087 D hypothetical protein 1017818..1018087 Streptococcus pneumoniae CGSP14 6217468 YP_001835765.1 CDS SPCG_1048 NC_010582.1 1018091 1018450 D hypothetical protein 1018091..1018450 Streptococcus pneumoniae CGSP14 6218549 YP_001835766.1 CDS SPCG_1049 NC_010582.1 1018669 1018812 D hypothetical protein 1018669..1018812 Streptococcus pneumoniae CGSP14 6217671 YP_001835767.1 CDS SPCG_1050 NC_010582.1 1018912 1019085 D hypothetical protein 1018912..1019085 Streptococcus pneumoniae CGSP14 6218572 YP_001835768.1 CDS SPCG_1051 NC_010582.1 1019066 1019236 D hypothetical protein 1019066..1019236 Streptococcus pneumoniae CGSP14 6217038 YP_001835769.1 CDS SPCG_1052 NC_010582.1 1019398 1021332 D endonuclease 1019398..1021332 Streptococcus pneumoniae CGSP14 6218016 YP_001835770.1 CDS SPCG_1053 NC_010582.1 1021292 1022635 D hypothetical protein 1021292..1022635 Streptococcus pneumoniae CGSP14 6217833 YP_001835771.1 CDS guaC NC_010582.1 1022810 1023796 D guanosine 5'-monophosphate oxidoreductase 1022810..1023796 Streptococcus pneumoniae CGSP14 6216688 YP_001835772.1 CDS rnc NC_010582.1 1024114 1024812 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 1024114..1024812 Streptococcus pneumoniae CGSP14 6217532 YP_001835773.1 CDS SPCG_1056 NC_010582.1 1024803 1028342 D hypothetical protein 1024803..1028342 Streptococcus pneumoniae CGSP14 6217737 YP_001835774.1 CDS SPCG_1057 NC_010582.1 1028339 1029133 D cof family protein 1028339..1029133 Streptococcus pneumoniae CGSP14 6217786 YP_001835775.1 CDS SPCG_1058 NC_010582.1 1029133 1029951 D cof family protein 1029133..1029951 Streptococcus pneumoniae CGSP14 6218157 YP_001835776.1 CDS ftsY NC_010582.1 1029955 1031244 D signal recognition particle-docking protein FtsY 1029955..1031244 Streptococcus pneumoniae CGSP14 6217826 YP_001835777.1 CDS zwf NC_010582.1 1031290 1032777 R catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate; glucose-6-phosphate 1-dehydrogenase complement(1031290..1032777) Streptococcus pneumoniae CGSP14 6217853 YP_001835778.1 CDS SPCG_1061 NC_010582.1 1032926 1033666 R amino acid ABC transporter ATP-binding protein complement(1032926..1033666) Streptococcus pneumoniae CGSP14 6217662 YP_001835779.1 CDS SPCG_1062 NC_010582.1 1033666 1035831 R amino acid ABC transporter amino acid-binding protein/permease complement(1033666..1035831) Streptococcus pneumoniae CGSP14 6218042 YP_001835780.1 CDS SPCG_1063 NC_010582.1 1036000 1036953 D hypothetical protein 1036000..1036953 Streptococcus pneumoniae CGSP14 6217278 YP_001835781.1 CDS uvrB NC_010582.1 1037030 1039018 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1037030..1039018 Streptococcus pneumoniae CGSP14 6217721 YP_001835782.1 CDS SPCG_1065 NC_010582.1 1039028 1039591 D acetyltransferase 1039028..1039591 Streptococcus pneumoniae CGSP14 6216371 YP_001835783.1 CDS SPCG_1066 NC_010582.1 1039557 1040045 D acetyltransferase 1039557..1040045 Streptococcus pneumoniae CGSP14 6217384 YP_001835784.1 CDS SPCG_1067 NC_010582.1 1040119 1040586 D mutT/nudix family protein 1040119..1040586 Streptococcus pneumoniae CGSP14 6217528 YP_001835785.1 CDS SPCG_1068 NC_010582.1 1040583 1041098 R biotin repressor family transcriptional regulator complement(1040583..1041098) Streptococcus pneumoniae CGSP14 6217376 YP_001835786.1 CDS SPCG_1069 NC_010582.1 1041110 1041691 R hypothetical protein complement(1041110..1041691) Streptococcus pneumoniae CGSP14 6218053 YP_001835787.1 CDS SPCG_1070 NC_010582.1 1041919 1042482 R membrane protein complement(1041919..1042482) Streptococcus pneumoniae CGSP14 6217910 YP_001835788.1 CDS SPCG_1071 NC_010582.1 1042466 1043017 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(1042466..1043017) Streptococcus pneumoniae CGSP14 6217915 YP_001835789.1 CDS SPCG_1072 NC_010582.1 1043029 1043733 R phosphopantothenate--cysteine ligase complement(1043029..1043733) Streptococcus pneumoniae CGSP14 6217753 YP_001835790.1 CDS fhs NC_010582.1 1043948 1045618 D catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate; formate--tetrahydrofolate ligase 1043948..1045618 Streptococcus pneumoniae CGSP14 6217567 YP_001835791.1 CDS mutY NC_010582.1 1045947 1047122 D A/G-specific adenine glycosylase 1045947..1047122 Streptococcus pneumoniae CGSP14 6217659 YP_001835792.1 CDS SPCG_1075 NC_010582.1 1047126 1047881 D DNA-binding response regulator 1047126..1047881 Streptococcus pneumoniae CGSP14 6216506 YP_001835793.1 CDS SPCG_1076 NC_010582.1 1047874 1049223 D sensory box sensor histidine kinase 1047874..1049223 Streptococcus pneumoniae CGSP14 6217121 YP_001835794.1 CDS vicX NC_010582.1 1049225 1050034 D vicX protein 1049225..1050034 Streptococcus pneumoniae CGSP14 6217487 YP_001835795.1 CDS SPCG_1078 NC_010582.1 1050065 1050367 D hypothetical protein 1050065..1050367 Streptococcus pneumoniae CGSP14 6217391 YP_001835796.1 CDS SPCG_1079 NC_010582.1 1050360 1050623 D hypothetical protein 1050360..1050623 Streptococcus pneumoniae CGSP14 6217968 YP_001835797.1 CDS SPCG_1080 NC_010582.1 1050598 1051254 D ion transporter 1050598..1051254 Streptococcus pneumoniae CGSP14 6217252 YP_001835798.1 CDS ldh NC_010582.1 1051582 1052580 R Converts (S)-lactate and NAD(+) to pyruvate and NADH; L-lactate dehydrogenase complement(1051582..1052580) Streptococcus pneumoniae CGSP14 6217533 YP_001835799.1 CDS SPCG_1082 NC_010582.1 1052705 1055230 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 1052705..1055230 Streptococcus pneumoniae CGSP14 6217838 YP_001835800.1 CDS SPCG_1083 NC_010582.1 1055230 1055973 D hypothetical protein 1055230..1055973 Streptococcus pneumoniae CGSP14 6218170 YP_001835801.1 CDS SPCG_1084 NC_010582.1 1056217 1057014 D FNT family protein 1056217..1057014 Streptococcus pneumoniae CGSP14 6217282 YP_001835802.1 CDS SPCG_1085 NC_010582.1 1057162 1057284 D O-acetylhomoserine sulfhydrylase, truncation 1057162..1057284 Streptococcus pneumoniae CGSP14 6218077 YP_001835803.1 CDS SPCG_1086 NC_010582.1 1057306 1058421 D O-acetylhomoserine sulfhydrylase, truncation 1057306..1058421 Streptococcus pneumoniae CGSP14 6217364 YP_001835804.1 CDS SPCG_1087 NC_010582.1 1058517 1059791 D hypothetical protein 1058517..1059791 Streptococcus pneumoniae CGSP14 6218413 YP_001835805.1 CDS SPCG_1088 NC_010582.1 1059803 1062988 D hypothetical protein 1059803..1062988 Streptococcus pneumoniae CGSP14 6217544 YP_001835806.1 CDS truB NC_010582.1 1063089 1063967 D catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs; tRNA pseudouridine synthase B 1063089..1063967 Streptococcus pneumoniae CGSP14 6216372 YP_001835807.1 CDS SPCG_1090 NC_010582.1 1064116 1064211 D hypothetical protein 1064116..1064211 Streptococcus pneumoniae CGSP14 6217744 YP_001835808.1 CDS SPCG_1091 NC_010582.1 1064208 1064510 D hypothetical protein 1064208..1064510 Streptococcus pneumoniae CGSP14 6216409 YP_001835809.1 CDS udK NC_010582.1 1064618 1065256 D functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor; uridine kinase 1064618..1065256 Streptococcus pneumoniae CGSP14 6217658 YP_001835810.1 CDS xseA NC_010582.1 1065378 1066724 D bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides; exodeoxyribonuclease VII large subunit 1065378..1066724 Streptococcus pneumoniae CGSP14 6217890 YP_001835811.1 CDS xseB NC_010582.1 1066702 1066914 D catalyzes the bidirectional exonucleolytic cleavage of DNA; exodeoxyribonuclease VII small subunit 1066702..1066914 Streptococcus pneumoniae CGSP14 6217531 YP_001835812.1 CDS SPCG_1095 NC_010582.1 1066911 1067786 D geranyltranstransferase 1066911..1067786 Streptococcus pneumoniae CGSP14 6217440 YP_001835813.1 CDS SPCG_1096 NC_010582.1 1067779 1068594 D hemolysin A 1067779..1068594 Streptococcus pneumoniae CGSP14 6217439 YP_001835814.1 CDS ahrC NC_010582.1 1068587 1069018 D transcriptional repressor 1068587..1069018 Streptococcus pneumoniae CGSP14 6217732 YP_001835815.1 CDS recN NC_010582.1 1069025 1070692 D DNA repair protein RecN 1069025..1070692 Streptococcus pneumoniae CGSP14 6218007 YP_001835816.1 CDS pphA NC_010582.1 1070694 1071422 D serine/threonine protein phosphatase 1070694..1071422 Streptococcus pneumoniae CGSP14 6217543 YP_001835817.1 CDS SPCG_1100 NC_010582.1 1071438 1073324 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 1071438..1073324 Streptococcus pneumoniae CGSP14 6218443 YP_001835818.1 CDS SPCG_1101 NC_010582.1 1073737 1074258 D PTS system transporter subunit IIA 1073737..1074258 Streptococcus pneumoniae CGSP14 6218586 YP_001835819.1 CDS SPCG_1102 NC_010582.1 1074296 1074598 D hypothetical protein 1074296..1074598 Streptococcus pneumoniae CGSP14 6218275 YP_001835820.1 CDS SPCG_1103 NC_010582.1 1075036 1075425 D IS1381 transposase protein B 1075036..1075425 Streptococcus pneumoniae CGSP14 6217937 YP_001835821.1 CDS SPCG_1104 NC_010582.1 1075594 1075938 D galactose mutarotase 1075594..1075938 Streptococcus pneumoniae CGSP14 6217127 YP_001835822.1 CDS lacA NC_010582.1 1076095 1076520 D catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; tagatose pathway for galactose utilization; galactose-6-phosphate isomerase subunit LacA 1076095..1076520 Streptococcus pneumoniae CGSP14 6217984 YP_001835823.1 CDS lacB NC_010582.1 1076551 1077066 D catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; galactose-6-phosphate isomerase subunit LacB 1076551..1077066 Streptococcus pneumoniae CGSP14 6217990 YP_001835824.1 CDS lacC NC_010582.1 1077077 1078006 D catalyzes the formation of tagatose 1,6-bisphosphate from tagatose 6-phosphate and ATP; tagatose-6-phosphate kinase 1077077..1078006 Streptococcus pneumoniae CGSP14 6217879 YP_001835825.1 CDS lacD NC_010582.1 1078008 1078988 D catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; tagatose 1,6-diphosphate aldolase 1078008..1078988 Streptococcus pneumoniae CGSP14 6217572 YP_001835826.1 CDS lacT NC_010582.1 1079222 1080058 D transcription antiterminator LacT 1079222..1080058 Streptococcus pneumoniae CGSP14 6217562 YP_001835827.1 CDS SPCG_1110 NC_010582.1 1080094 1080411 D PTS system lactose-specific transporter subunit IIA 1080094..1080411 Streptococcus pneumoniae CGSP14 6217738 YP_001835828.1 CDS SPCG_1111 NC_010582.1 1080383 1082107 D PTS system lactose-specific transporter subunit IIBC 1080383..1082107 Streptococcus pneumoniae CGSP14 6217555 YP_001835829.1 CDS lacG NC_010582.1 1082313 1083728 D catalyzes the formation of 6-phospho-galactose from a 6-phospho-beta-galactoside; 6-phospho-beta-galactosidase 1082313..1083728 Streptococcus pneumoniae CGSP14 6218043 YP_001835830.1 CDS SPCG_1113 NC_010582.1 1083771 1084028 D hypothetical protein 1083771..1084028 Streptococcus pneumoniae CGSP14 6217734 YP_001835831.1 CDS lacR NC_010582.1 1084307 1085068 R lactose phosphotransferase system repressor complement(1084307..1085068) Streptococcus pneumoniae CGSP14 6217601 YP_001835832.1 CDS SPCG_1115 NC_010582.1 1085378 1085896 D degenerate transposase 1085378..1085896 Streptococcus pneumoniae CGSP14 6217913 YP_001835833.1 CDS SPCG_1116 NC_010582.1 1086177 1086704 D degenerate transposase 1086177..1086704 Streptococcus pneumoniae CGSP14 6218554 YP_001835834.1 CDS nrdF NC_010582.1 1086742 1087704 R B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta complement(1086742..1087704) Streptococcus pneumoniae CGSP14 6217125 YP_001835835.1 CDS nrdE NC_010582.1 1087892 1090051 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(1087892..1090051) Streptococcus pneumoniae CGSP14 6218446 YP_001835836.1 CDS nrdH NC_010582.1 1090132 1090368 R nrdH-redoxin complement(1090132..1090368) Streptococcus pneumoniae CGSP14 6217602 YP_001835837.1 CDS SPCG_1120 NC_010582.1 1090701 1090964 D phosphocarrier protein HPr 1090701..1090964 Streptococcus pneumoniae CGSP14 6218429 YP_001835838.1 CDS SPCG_1121 NC_010582.1 1090970 1092703 D phosphoenolpyruvate-protein phosphotransferase 1090970..1092703 Streptococcus pneumoniae CGSP14 6217847 YP_001835839.1 CDS SPCG_1122 NC_010582.1 1092922 1095480 D hypothetical protein 1092922..1095480 Streptococcus pneumoniae CGSP14 6217757 YP_001835840.1 CDS SPCG_1123 NC_010582.1 1095622 1095996 D hypothetical protein 1095622..1095996 Streptococcus pneumoniae CGSP14 6217888 YP_001835841.1 CDS SPCG_1124 NC_010582.1 1096072 1096284 D degenerate transposase 1096072..1096284 Streptococcus pneumoniae CGSP14 6217846 YP_001835842.1 CDS SPCG_1125 NC_010582.1 1096449 1097387 D hypothetical protein 1096449..1097387 Streptococcus pneumoniae CGSP14 6218008 YP_001835843.1 CDS SPCG_1126 NC_010582.1 1097409 1098161 D HAD superfamily hydrolase 1097409..1098161 Streptococcus pneumoniae CGSP14 6217868 YP_001835844.1 CDS SPCG_1127 NC_010582.1 1098219 1098821 D hypothetical protein 1098219..1098821 Streptococcus pneumoniae CGSP14 6218528 YP_001835845.1 CDS ung NC_010582.1 1098942 1099610 D Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine; uracil-DNA glycosylase 1098942..1099610 Streptococcus pneumoniae CGSP14 6216469 YP_001835846.1 CDS mutX NC_010582.1 1099620 1100084 D mutator MutT protein 1099620..1100084 Streptococcus pneumoniae CGSP14 6218513 YP_001835847.1 CDS pyrC NC_010582.1 1100097 1101365 D catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis; dihydroorotase 1100097..1101365 Streptococcus pneumoniae CGSP14 6218589 YP_001835848.1 CDS SPCG_1131 NC_010582.1 1101650 1103011 D MATE efflux family protein 1101650..1103011 Streptococcus pneumoniae CGSP14 6216840 YP_001835849.1 CDS SPCG_1132 NC_010582.1 1103008 1103118 R hypothetical protein complement(1103008..1103118) Streptococcus pneumoniae CGSP14 6217311 YP_001835850.1 CDS acoA NC_010582.1 1103165 1104133 D acetoin dehydrogenase, E1 component subunit alpha 1103165..1104133 Streptococcus pneumoniae CGSP14 6218594 YP_001835851.1 CDS acoB NC_010582.1 1104149 1105141 D acetoin dehydrogenase, E1 component subunit beta 1104149..1105141 Streptococcus pneumoniae CGSP14 6216404 YP_001835852.1 CDS acoC NC_010582.1 1105275 1106402 D unlike PdhC proteins from other organisms, some Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma hyopneumonia the PdhD proteins contains the lipoyl domain; dihydrolipoamide acetyltransferase 1105275..1106402 Streptococcus pneumoniae CGSP14 6217448 YP_001835853.1 CDS acoL NC_010582.1 1106448 1108151 D acetoin dehydrogenase complex, E3 component, dihydrolipoamide dehydrogenase 1106448..1108151 Streptococcus pneumoniae CGSP14 6218078 YP_001835854.1 CDS SPCG_1137 NC_010582.1 1108215 1109204 D lipoate-protein ligase 1108215..1109204 Streptococcus pneumoniae CGSP14 6218003 YP_001835855.1 CDS xerS NC_010582.1 1109269 1110339 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerS; site-specific tyrosine recombinase XerS complement(1109269..1110339) Streptococcus pneumoniae CGSP14 6217460 YP_001835856.1 CDS SPCG_1139 NC_010582.1 1110923 1112488 R voltage-gated chloride channel family protein complement(1110923..1112488) Streptococcus pneumoniae CGSP14 6216815 YP_001835857.1 CDS rnhB NC_010582.1 1112489 1113268 R RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids; ribonuclease HII complement(1112489..1113268) Streptococcus pneumoniae CGSP14 6217669 YP_001835858.1 CDS rbgA NC_010582.1 1113255 1114106 R essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc); ribosomal biogenesis GTPase complement(1113255..1114106) Streptococcus pneumoniae CGSP14 6217967 YP_001835859.1 CDS zmpD NC_010582.1 1114351 1119834 R zinc metalloprotease ZmpD complement(1114351..1119834) Streptococcus pneumoniae CGSP14 6216430 YP_001835860.1 CDS iga NC_010582.1 1119878 1125604 R immunoglobulin A1 protease complement(1119878..1125604) Streptococcus pneumoniae CGSP14 6216375 YP_001835861.1 CDS SPCG_1144 NC_010582.1 1125813 1126991 R hypothetical protein complement(1125813..1126991) Streptococcus pneumoniae CGSP14 6216334 YP_001835862.1 CDS rexA NC_010582.1 1127161 1130811 R exonuclease RexA complement(1127161..1130811) Streptococcus pneumoniae CGSP14 6216435 YP_001835863.1 CDS rexB NC_010582.1 1130808 1134110 R exonuclease RexB complement(1130808..1134110) Streptococcus pneumoniae CGSP14 6217021 YP_001835864.1 CDS SPCG_1147 NC_010582.1 1134591 1134938 D IS630-Spn1, transposase Orf1 1134591..1134938 Streptococcus pneumoniae CGSP14 6218378 YP_001835865.1 CDS SPCG_1148 NC_010582.1 1135487 1136005 D degenerate transposase 1135487..1136005 Streptococcus pneumoniae CGSP14 6216330 YP_001835866.1 CDS SPCG_1149 NC_010582.1 1136286 1136813 D degenerate transposase 1136286..1136813 Streptococcus pneumoniae CGSP14 6218377 YP_001835867.1 CDS eno NC_010582.1 1136988 1138292 R enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase complement(1136988..1138292) Streptococcus pneumoniae CGSP14 6216438 YP_001835868.1 CDS SPCG_1151 NC_010582.1 1138456 1138902 D hypothetical protein 1138456..1138902 Streptococcus pneumoniae CGSP14 6217839 YP_001835869.1 CDS SPCG_1152 NC_010582.1 1138899 1139228 R hypothetical protein complement(1138899..1139228) Streptococcus pneumoniae CGSP14 6217725 YP_001835870.1 CDS SPCG_1153 NC_010582.1 1139197 1140027 R hypothetical protein complement(1139197..1140027) Streptococcus pneumoniae CGSP14 6217563 YP_001835871.1 CDS SPCG_1154 NC_010582.1 1140024 1140182 R phosphoserine phosphatase, truncation complement(1140024..1140182) Streptococcus pneumoniae CGSP14 6217522 YP_001835872.1 CDS SPCG_1155 NC_010582.1 1140297 1140668 R phosphoserine phosphatase complement(1140297..1140668) Streptococcus pneumoniae CGSP14 6218021 YP_001835873.1 CDS glgA NC_010582.1 1140727 1142160 R catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose; glycogen synthase complement(1140727..1142160) Streptococcus pneumoniae CGSP14 6217708 YP_001835874.1 CDS glgD NC_010582.1 1142157 1143296 R glycogen biosynthesis protein GlgD complement(1142157..1143296) Streptococcus pneumoniae CGSP14 6218564 YP_001835875.1 CDS glgC NC_010582.1 1143286 1144428 R catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate; glucose-1-phosphate adenylyltransferase complement(1143286..1144428) Streptococcus pneumoniae CGSP14 6216341 YP_001835876.1 CDS glgB NC_010582.1 1144418 1146346 R catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain; glycogen branching protein complement(1144418..1146346) Streptococcus pneumoniae CGSP14 6216383 YP_001835877.1 CDS gapN NC_010582.1 1146795 1148219 R glyceraldehyde-3-phosphate dehydrogenase complement(1146795..1148219) Streptococcus pneumoniae CGSP14 6218563 YP_001835878.1 CDS SPCG_1161 NC_010582.1 1148551 1148712 R hypothetical protein complement(1148551..1148712) Streptococcus pneumoniae CGSP14 6218402 YP_001835879.1 CDS pulI NC_010582.1 1148763 1151042 R pullulanase complement(1148763..1151042) Streptococcus pneumoniae CGSP14 6216432 YP_001835880.1 CDS ligA NC_010582.1 1151154 1153112 R this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB; NAD-dependent DNA ligase LigA complement(1151154..1153112) Streptococcus pneumoniae CGSP14 6216373 YP_001835881.1 CDS SPCG_1164 NC_010582.1 1153205 1154383 R transporter complement(1153205..1154383) Streptococcus pneumoniae CGSP14 6216364 YP_001835882.1 CDS SPCG_1165 NC_010582.1 1154463 1154555 R hypothetical protein complement(1154463..1154555) Streptococcus pneumoniae CGSP14 6217858 YP_001835883.1 CDS SPCG_1166 NC_010582.1 1154689 1155339 R hypothetical protein complement(1154689..1155339) Streptococcus pneumoniae CGSP14 6217524 YP_001835884.1 CDS SPCG_1167 NC_010582.1 1155312 1157213 R ABC transporter ATP-binding protein complement(1155312..1157213) Streptococcus pneumoniae CGSP14 6217642 YP_001835885.1 CDS hlpA NC_010582.1 1157643 1157918 R DNA-binding protein HU complement(1157643..1157918) Streptococcus pneumoniae CGSP14 6217382 YP_001835886.1 CDS SPCG_1169 NC_010582.1 1158025 1158864 R degV family protein complement(1158025..1158864) Streptococcus pneumoniae CGSP14 6217956 YP_001835887.1 CDS SPCG_1170 NC_010582.1 1159006 1159854 D hypothetical protein 1159006..1159854 Streptococcus pneumoniae CGSP14 6218553 YP_001835888.1 CDS mreA NC_010582.1 1159947 1160864 R catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities; bifunctional riboflavin kinase/FMN adenylyltransferase complement(1159947..1160864) Streptococcus pneumoniae CGSP14 6216394 YP_001835889.1 CDS SPCG_1172 NC_010582.1 1161202 1161330 D hypothetical protein 1161202..1161330 Streptococcus pneumoniae CGSP14 6216322 YP_001835890.1 CDS SPCG_1173 NC_010582.1 1161302 1161472 D hypothetical protein 1161302..1161472 Streptococcus pneumoniae CGSP14 6217289 YP_001835891.1 CDS rpmA NC_010582.1 1161818 1162111 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(1161818..1162111) Streptococcus pneumoniae CGSP14 6216820 YP_001835892.1 CDS SPCG_1175 NC_010582.1 1162128 1162472 R hypothetical protein complement(1162128..1162472) Streptococcus pneumoniae CGSP14 6218577 YP_001835893.1 CDS rplU NC_010582.1 1162488 1162877 R 50S ribosomal protein L21 complement(1162488..1162877) Streptococcus pneumoniae CGSP14 6216433 YP_001835894.1 CDS SPCG_1177 NC_010582.1 1162990 1163688 R hypothetical protein complement(1162990..1163688) Streptococcus pneumoniae CGSP14 6218559 YP_001835895.1 CDS SPCG_1178 NC_010582.1 1164090 1164389 D hypothetical protein 1164090..1164389 Streptococcus pneumoniae CGSP14 6216384 YP_001835896.1 CDS eutD NC_010582.1 1164730 1165704 R in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta; phosphotransacetylase complement(1164730..1165704) Streptococcus pneumoniae CGSP14 6216392 YP_001835897.1 CDS rluD NC_010582.1 1165748 1166644 R ribosomal large subunit pseudouridine synthase D complement(1165748..1166644) Streptococcus pneumoniae CGSP14 6218149 YP_001835898.1 CDS ppnK NC_010582.1 1166641 1167471 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(1166641..1167471) Streptococcus pneumoniae CGSP14 6217139 YP_001835899.1 CDS SPCG_1182 NC_010582.1 1167443 1168114 R hypothetical protein complement(1167443..1168114) Streptococcus pneumoniae CGSP14 6218055 YP_001835900.1 CDS SPCG_1183 NC_010582.1 1168242 1168811 D hypothetical protein 1168242..1168811 Streptococcus pneumoniae CGSP14 6218224 YP_001835901.1 CDS SPCG_1184 NC_010582.1 1168924 1169883 D catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; ribose-phosphate pyrophosphokinase 1168924..1169883 Streptococcus pneumoniae CGSP14 6217859 YP_001835902.1 CDS SPCG_1185 NC_010582.1 1169893 1171008 D class-V aminotransferase 1169893..1171008 Streptococcus pneumoniae CGSP14 6216419 YP_001835903.1 CDS SPCG_1186 NC_010582.1 1171013 1171360 D hypothetical protein 1171013..1171360 Streptococcus pneumoniae CGSP14 6218405 YP_001835904.1 CDS SPCG_1187 NC_010582.1 1171332 1171583 D hypothetical protein 1171332..1171583 Streptococcus pneumoniae CGSP14 6216350 YP_001835905.1 CDS SPCG_1188 NC_010582.1 1171666 1172307 D modulates transcription in response to the NADH/NAD(+) redox state; redox-sensing transcriptional repressor Rex 1171666..1172307 Streptococcus pneumoniae CGSP14 6218411 YP_001835906.1 CDS SPCG_1189 NC_010582.1 1172325 1173014 D glutamine amidotransferase 1172325..1173014 Streptococcus pneumoniae CGSP14 6216354 YP_001835907.1 CDS radC NC_010582.1 1173011 1173706 R Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase; DNA repair protein RadC complement(1173011..1173706) Streptococcus pneumoniae CGSP14 6216439 YP_001835908.1 CDS pcrA NC_010582.1 1173734 1176025 R ATP-dependent DNA helicase PcrA complement(1173734..1176025) Streptococcus pneumoniae CGSP14 6216368 YP_001835909.1 CDS SPCG_1192 NC_010582.1 1176216 1176605 R IS1381 transposase protein B complement(1176216..1176605) Streptococcus pneumoniae CGSP14 6216380 YP_001835910.1 CDS SPCG_1193 NC_010582.1 1176631 1176939 R IS1381 transposase protein A complement(1176631..1176939) Streptococcus pneumoniae CGSP14 6217657 YP_001835911.1 CDS map NC_010582.1 1177401 1178261 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; methionine aminopeptidase complement(1177401..1178261) Streptococcus pneumoniae CGSP14 6216367 YP_001835912.1 CDS SPCG_1195 NC_010582.1 1178277 1179554 R hypothetical protein complement(1178277..1179554) Streptococcus pneumoniae CGSP14 6217887 YP_001835913.1 CDS SPCG_1196 NC_010582.1 1179547 1180104 R acetyltransferase complement(1179547..1180104) Streptococcus pneumoniae CGSP14 6217445 YP_001835914.1 CDS murZ NC_010582.1 1180114 1181373 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1180114..1181373) Streptococcus pneumoniae CGSP14 6217143 YP_001835915.1 CDS SPCG_1198 NC_010582.1 1182575 1183093 D degenerate transposase 1182575..1183093 Streptococcus pneumoniae CGSP14 6218056 YP_001835916.1 CDS SPCG_1199 NC_010582.1 1183374 1183901 D degenerate transposase 1183374..1183901 Streptococcus pneumoniae CGSP14 6216344 YP_001835917.1 CDS SPCG_1200 NC_010582.1 1183952 1184110 R hypothetical protein complement(1183952..1184110) Streptococcus pneumoniae CGSP14 6216339 YP_001835918.1 CDS obgE NC_010582.1 1184120 1185430 R essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE complement(1184120..1185430) Streptococcus pneumoniae CGSP14 6217255 YP_001835919.1 CDS SPCG_1202 NC_010582.1 1185494 1185628 R hypothetical protein complement(1185494..1185628) Streptococcus pneumoniae CGSP14 6218266 YP_001835920.1 CDS SPCG_1203 NC_010582.1 1185687 1185863 R hypothetical protein complement(1185687..1185863) Streptococcus pneumoniae CGSP14 6216405 YP_001835921.1 CDS SPCG_1204 NC_010582.1 1185894 1187219 R group 1 glycosyl transferase complement(1185894..1187219) Streptococcus pneumoniae CGSP14 6218400 YP_001835922.1 CDS cpoA NC_010582.1 1187235 1188317 R glycosyl transferase CpoA complement(1187235..1188317) Streptococcus pneumoniae CGSP14 6216391 YP_001835923.1 CDS SPCG_1206 NC_010582.1 1188393 1188755 R hypothetical protein complement(1188393..1188755) Streptococcus pneumoniae CGSP14 6216358 YP_001835924.1 CDS rpoD NC_010582.1 1188736 1189845 R sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; primary sigma factor of bacterium; RNA polymerase sigma factor RpoD complement(1188736..1189845) Streptococcus pneumoniae CGSP14 6217292 YP_001835925.1 CDS dnaG NC_010582.1 1189848 1191623 R synthesizes RNA primers at the replication forks; DNA primase complement(1189848..1191623) Streptococcus pneumoniae CGSP14 6216577 YP_001835926.1 CDS SPCG_1209 NC_010582.1 1191698 1192456 R ABC transporter ATP-binding protein complement(1191698..1192456) Streptococcus pneumoniae CGSP14 6217731 YP_001835927.1 CDS SPCG_1210 NC_010582.1 1192453 1193319 R hypothetical protein complement(1192453..1193319) Streptococcus pneumoniae CGSP14 6217556 YP_001835928.1 CDS SPCG_1211 NC_010582.1 1193388 1194422 R hypothetical protein complement(1193388..1194422) Streptococcus pneumoniae CGSP14 6217971 YP_001835929.1 CDS ppc NC_010582.1 1194805 1197501 R catalyzes the formation of oxaloacetate from phosphoenolpyruvate; phosphoenolpyruvate carboxylase complement(1194805..1197501) Streptococcus pneumoniae CGSP14 6217481 YP_001835930.1 CDS ftsW NC_010582.1 1197521 1198750 R cell division protein FtsW complement(1197521..1198750) Streptococcus pneumoniae CGSP14 6217957 YP_001835931.1 CDS SPCG_1214 NC_010582.1 1199013 1199207 R IS1381 transposase protein A, truncation complement(1199013..1199207) Streptococcus pneumoniae CGSP14 6217100 YP_001835932.1 CDS SPCG_1215 NC_010582.1 1199312 1199644 R hypothetical protein complement(1199312..1199644) Streptococcus pneumoniae CGSP14 6218130 YP_001835933.1 CDS SPCG_1216 NC_010582.1 1199830 1200438 R hypothetical protein complement(1199830..1200438) Streptococcus pneumoniae CGSP14 6217548 YP_001835934.1 CDS SPCG_1217 NC_010582.1 1200522 1202315 R resolvase family site-specific recombinase complement(1200522..1202315) Streptococcus pneumoniae CGSP14 6217318 YP_001835935.1 CDS SPCG_1218 NC_010582.1 1202765 1202968 R hypothetical protein complement(1202765..1202968) Streptococcus pneumoniae CGSP14 6217061 YP_001835936.1 CDS SPCG_1219 NC_010582.1 1203392 1203607 D degenerate transposase 1203392..1203607 Streptococcus pneumoniae CGSP14 6217585 YP_001835937.1 CDS SPCG_1220 NC_010582.1 1203732 1204106 D degenerate transposase 1203732..1204106 Streptococcus pneumoniae CGSP14 6217711 YP_001835938.1 CDS SPCG_1221 NC_010582.1 1204091 1204411 D degenerate transposase 1204091..1204411 Streptococcus pneumoniae CGSP14 6217182 YP_001835939.1 CDS SPCG_1222 NC_010582.1 1205044 1205829 R hypothetical protein complement(1205044..1205829) Streptococcus pneumoniae CGSP14 6217718 YP_001835940.1 CDS SPCG_1223 NC_010582.1 1206088 1206699 R daunorubicin resistance transmembrane protein complement(1206088..1206699) Streptococcus pneumoniae CGSP14 6218122 YP_001835941.1 CDS SPCG_1224 NC_010582.1 1206650 1207234 R hypothetical protein complement(1206650..1207234) Streptococcus pneumoniae CGSP14 6218001 YP_001835942.1 CDS SPCG_1225 NC_010582.1 1207295 1207504 R hypothetical protein complement(1207295..1207504) Streptococcus pneumoniae CGSP14 6217690 YP_001835943.1 CDS SPCG_1226 NC_010582.1 1208658 1209449 R hypothetical protein complement(1208658..1209449) Streptococcus pneumoniae CGSP14 6218385 YP_001835944.1 CDS SPCG_1227 NC_010582.1 1209526 1211163 R methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; methionyl-tRNA synthetase complement(1209526..1211163) Streptococcus pneumoniae CGSP14 6217515 YP_001835945.1 CDS SPCG_1228 NC_010582.1 1211231 1211905 R chloramphenicol acetyltransferase complement(1211231..1211905) Streptococcus pneumoniae CGSP14 6218500 YP_001835946.1 CDS SPCG_1229 NC_010582.1 1212706 1213704 D IS1239 transposase 1212706..1213704 Streptococcus pneumoniae CGSP14 6218469 YP_001835947.1 CDS SPCG_1230 NC_010582.1 1214276 1215136 R DNA processing protein DprA complement(1214276..1215136) Streptococcus pneumoniae CGSP14 6216401 YP_001835948.1 CDS SPCG_1231 NC_010582.1 1215220 1215909 R licC protein complement(1215220..1215909) Streptococcus pneumoniae CGSP14 6218457 YP_001835949.1 CDS SPCG_1232 NC_010582.1 1215921 1216811 R licB protein complement(1215921..1216811) Streptococcus pneumoniae CGSP14 6217770 YP_001835950.1 CDS pck NC_010582.1 1216789 1217658 R choline kinase complement(1216789..1217658) Streptococcus pneumoniae CGSP14 6216351 YP_001835951.1 CDS SPCG_1234 NC_010582.1 1217675 1218715 R zinc-containing alcohol dehydrogenase complement(1217675..1218715) Streptococcus pneumoniae CGSP14 6217767 YP_001835952.1 CDS ispD NC_010582.1 1218702 1219409 R 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1218702..1219409) Streptococcus pneumoniae CGSP14 6218432 YP_001835953.1 CDS SPCG_1236 NC_010582.1 1219745 1221232 D polysaccharide biosynthesis protein 1219745..1221232 Streptococcus pneumoniae CGSP14 6217745 YP_001835954.1 CDS licD1 NC_010582.1 1221242 1222045 D licD1 protein 1221242..1222045 Streptococcus pneumoniae CGSP14 6217124 YP_001835955.1 CDS licD2 NC_010582.1 1222014 1222856 D licD2 protein 1222014..1222856 Streptococcus pneumoniae CGSP14 6218524 YP_001835956.1 CDS carB NC_010582.1 1223131 1226307 R four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit complement(1223131..1226307) Streptococcus pneumoniae CGSP14 6218082 YP_001835957.1 CDS carA NC_010582.1 1226620 1227699 R catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit complement(1226620..1227699) Streptococcus pneumoniae CGSP14 6218083 YP_001835958.1 CDS pyrB NC_010582.1 1227749 1228672 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(1227749..1228672) Streptococcus pneumoniae CGSP14 6217747 YP_001835959.1 CDS pyrR NC_010582.1 1228691 1229212 R regulates pyrimidine biosynthesis by binding to the mRNA of the pyr genes, also has been shown to have uracil phosphoribosyltransferase activity; bifunctional pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase complement(1228691..1229212) Streptococcus pneumoniae CGSP14 6218416 YP_001835960.1 CDS nth NC_010582.1 1229423 1230052 R endonuclease III complement(1229423..1230052) Streptococcus pneumoniae CGSP14 6216398 YP_001835961.1 CDS SPCG_1244 NC_010582.1 1230052 1230594 R hypothetical protein complement(1230052..1230594) Streptococcus pneumoniae CGSP14 6218431 YP_001835962.1 CDS SPCG_1245 NC_010582.1 1231320 1232879 D ABC transporter ATP-binding protein 1231320..1232879 Streptococcus pneumoniae CGSP14 6218438 YP_001835963.1 CDS htpX NC_010582.1 1233028 1233936 R metalloprotease; heat shock protein HtpX complement(1233028..1233936) Streptococcus pneumoniae CGSP14 6216338 YP_001835964.1 CDS lemA NC_010582.1 1233929 1234489 R hypothetical protein complement(1233929..1234489) Streptococcus pneumoniae CGSP14 6218376 YP_001835965.1 CDS gidB NC_010582.1 1234559 1235296 D glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA; 16S rRNA methyltransferase GidB 1234559..1235296 Streptococcus pneumoniae CGSP14 6218399 YP_001835966.1 CDS pyrP NC_010582.1 1235612 1236931 D uracil permease 1235612..1236931 Streptococcus pneumoniae CGSP14 6218436 YP_001835967.1 CDS ffh NC_010582.1 1237126 1238697 R signal recognition particle protein complement(1237126..1238697) Streptococcus pneumoniae CGSP14 6218510 YP_001835968.1 CDS SPCG_1251 NC_010582.1 1238709 1239041 R DNA-binding protein complement(1238709..1239041) Streptococcus pneumoniae CGSP14 6218516 YP_001835969.1 CDS SPCG_1252 NC_010582.1 1239132 1239509 R hypothetical protein complement(1239132..1239509) Streptococcus pneumoniae CGSP14 6218474 YP_001835970.1 CDS SPCG_1253 NC_010582.1 1239485 1240885 D hypothetical protein 1239485..1240885 Streptococcus pneumoniae CGSP14 6218587 YP_001835971.1 CDS SPCG_1254 NC_010582.1 1240898 1241704 D Cof family protein 1240898..1241704 Streptococcus pneumoniae CGSP14 6218440 YP_001835972.1 CDS SPCG_1255 NC_010582.1 1241915 1243690 R hypothetical protein complement(1241915..1243690) Streptococcus pneumoniae CGSP14 6218397 YP_001835973.1 CDS SPCG_1256 NC_010582.1 1244176 1245357 R choline binding protein PcpA complement(1244176..1245357) Streptococcus pneumoniae CGSP14 6216581 YP_001835974.1 CDS SPCG_1257 NC_010582.1 1245370 1246590 R surface protein A complement(1245370..1246590) Streptococcus pneumoniae CGSP14 6217494 YP_001835975.1 CDS SPCG_1258 NC_010582.1 1246618 1247538 D rgg protein 1246618..1247538 Streptococcus pneumoniae CGSP14 6216366 YP_001835976.1 CDS SPCG_1259 NC_010582.1 1247770 1247991 R hypothetical protein complement(1247770..1247991) Streptococcus pneumoniae CGSP14 6216349 YP_001835977.1 CDS rplS NC_010582.1 1248218 1248565 R this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 complement(1248218..1248565) Streptococcus pneumoniae CGSP14 6216568 YP_001835978.1 CDS crcB NC_010582.1 1248684 1249013 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1248684..1249013) Streptococcus pneumoniae CGSP14 6216355 YP_001835979.1 CDS crcB NC_010582.1 1249007 1249381 R may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling; camphor resistance protein CrcB complement(1249007..1249381) Streptococcus pneumoniae CGSP14 6217756 YP_001835980.1 CDS SPCG_1263 NC_010582.1 1249378 1249644 R hypothetical protein complement(1249378..1249644) Streptococcus pneumoniae CGSP14 6217577 YP_001835981.1 CDS flaV NC_010582.1 1249760 1250203 R An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; flavodoxin complement(1249760..1250203) Streptococcus pneumoniae CGSP14 6217870 YP_001835982.1 CDS SPCG_1265 NC_010582.1 1250295 1251242 D DHH subfamily 1 protein 1250295..1251242 Streptococcus pneumoniae CGSP14 6217587 YP_001835983.1 CDS rpmE NC_010582.1 1251296 1251580 D 50S ribosomal protein L31 1251296..1251580 Streptococcus pneumoniae CGSP14 6217381 YP_001835984.1 CDS SPCG_1267 NC_010582.1 1251637 1252242 R hypothetical protein complement(1251637..1252242) Streptococcus pneumoniae CGSP14 6216600 YP_001835985.1 CDS SPCG_1268 NC_010582.1 1252190 1253194 R hypothetical protein complement(1252190..1253194) Streptococcus pneumoniae CGSP14 6218452 YP_001835986.1 CDS SPCG_1269 NC_010582.1 1253246 1253368 R hypothetical protein complement(1253246..1253368) Streptococcus pneumoniae CGSP14 6217451 YP_001835987.1 CDS SPCG_1270 NC_010582.1 1253365 1253499 R hypothetical protein complement(1253365..1253499) Streptococcus pneumoniae CGSP14 6216417 YP_001835988.1 CDS SPCG_1271 NC_010582.1 1253749 1253844 R hypothetical protein complement(1253749..1253844) Streptococcus pneumoniae CGSP14 6216382 YP_001835989.1 CDS gdhA NC_010582.1 1254186 1255532 D converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; glutamate dehydrogenase 1254186..1255532 Streptococcus pneumoniae CGSP14 6218579 YP_001835990.1 CDS SPCG_1273 NC_010582.1 1255821 1259432 R glutamate dehydrogenase complement(1255821..1259432) Streptococcus pneumoniae CGSP14 6217612 YP_001835991.1 CDS SPCG_1274 NC_010582.1 1259712 1260899 R site-specific recombinase complement(1259712..1260899) Streptococcus pneumoniae CGSP14 6216340 YP_001835992.1 CDS SPCG_1275 NC_010582.1 1260871 1261179 R hypothetical protein complement(1260871..1261179) Streptococcus pneumoniae CGSP14 6218359 YP_001835993.1 CDS SPCG_1276 NC_010582.1 1261741 1263570 R Tn5252, relaxase complement(1261741..1263570) Streptococcus pneumoniae CGSP14 6216347 YP_001835994.1 CDS SPCG_1277 NC_010582.1 1263557 1263922 R Tn5252, ORF 9 protein complement(1263557..1263922) Streptococcus pneumoniae CGSP14 6218040 YP_001835995.1 CDS SPCG_1278 NC_010582.1 1263927 1264283 R Tn5252, ORF 10 protein complement(1263927..1264283) Streptococcus pneumoniae CGSP14 6217875 YP_001835996.1 CDS SPCG_1279 NC_010582.1 1264667 1264921 R hypothetical protein complement(1264667..1264921) Streptococcus pneumoniae CGSP14 6218450 YP_001835997.1 CDS SPCG_1280 NC_010582.1 1264987 1268991 R DNA-dependent ATPase I and helicase II complement(1264987..1268991) Streptococcus pneumoniae CGSP14 6216393 YP_001835998.1 CDS SPCG_1281 NC_010582.1 1269113 1269499 R hypothetical protein complement(1269113..1269499) Streptococcus pneumoniae CGSP14 6216402 YP_001835999.1 CDS SPCG_1282 NC_010582.1 1269571 1270521 R hypothetical protein complement(1269571..1270521) Streptococcus pneumoniae CGSP14 6217665 YP_001836000.1 CDS SPCG_1283 NC_010582.1 1270606 1271724 R hypothetical protein complement(1270606..1271724) Streptococcus pneumoniae CGSP14 6217666 YP_001836001.1 CDS SPCG_1284 NC_010582.1 1271986 1273821 R hypothetical protein complement(1271986..1273821) Streptococcus pneumoniae CGSP14 6216818 YP_001836002.1 CDS SPCG_1285 NC_010582.1 1274199 1274477 R hypothetical protein complement(1274199..1274477) Streptococcus pneumoniae CGSP14 6218360 YP_001836003.1 CDS SPCG_1286 NC_010582.1 1274452 1275156 R phosphoserine phosphatase complement(1274452..1275156) Streptococcus pneumoniae CGSP14 6216771 YP_001836004.1 CDS SPCG_1287 NC_010582.1 1275209 1275775 R hypothetical protein complement(1275209..1275775) Streptococcus pneumoniae CGSP14 6216362 YP_001836005.1 CDS SPCG_1288 NC_010582.1 1275868 1276092 R hypothetical protein complement(1275868..1276092) Streptococcus pneumoniae CGSP14 6216400 YP_001836006.1 CDS SPCG_1289 NC_010582.1 1276181 1276798 R hypothetical protein complement(1276181..1276798) Streptococcus pneumoniae CGSP14 6217106 YP_001836007.1 CDS SPCG_1290 NC_010582.1 1277120 1277842 R hypothetical protein complement(1277120..1277842) Streptococcus pneumoniae CGSP14 6217081 YP_001836008.1 CDS SPCG_1291 NC_010582.1 1278159 1279094 D replication initiation protein Rep(RC) 1278159..1279094 Streptococcus pneumoniae CGSP14 6216502 YP_001836009.1 CDS SPCG_1292 NC_010582.1 1279959 1280609 R chloramphenicol acetyltransferase complement(1279959..1280609) Streptococcus pneumoniae CGSP14 6217002 YP_001836010.1 CDS SPCG_1293 NC_010582.1 1280780 1281028 R hypothetical protein complement(1280780..1281028) Streptococcus pneumoniae CGSP14 6216742 YP_001836011.1 CDS SPCG_1294 NC_010582.1 1281267 1282055 R hypothetical protein complement(1281267..1282055) Streptococcus pneumoniae CGSP14 6217281 YP_001836012.1 CDS SPCG_1295 NC_010582.1 1282531 1283289 R hypothetical protein complement(1282531..1283289) Streptococcus pneumoniae CGSP14 6216983 YP_001836013.1 CDS SPCG_1296 NC_010582.1 1283289 1283765 R transcriptional regulator complement(1283289..1283765) Streptococcus pneumoniae CGSP14 6216667 YP_001836014.1 CDS SPCG_1297 NC_010582.1 1283835 1284107 R hypothetical protein complement(1283835..1284107) Streptococcus pneumoniae CGSP14 6217202 YP_001836015.1 CDS SPCG_1298 NC_010582.1 1284145 1284528 R hypothetical protein complement(1284145..1284528) Streptococcus pneumoniae CGSP14 6216984 YP_001836016.1 CDS SPCG_1299 NC_010582.1 1284525 1284758 R hypothetical protein complement(1284525..1284758) Streptococcus pneumoniae CGSP14 6216928 YP_001836017.1 CDS SPCG_1300 NC_010582.1 1284809 1285894 R hypothetical protein complement(1284809..1285894) Streptococcus pneumoniae CGSP14 6216588 YP_001836018.1 CDS SPCG_1301 NC_010582.1 1285904 1286545 R parvulin-like peptidyl-prolyl isomerase complement(1285904..1286545) Streptococcus pneumoniae CGSP14 6216957 YP_001836019.1 CDS SPCG_1302 NC_010582.1 1286705 1286902 D hypothetical protein 1286705..1286902 Streptococcus pneumoniae CGSP14 6217723 YP_001836020.1 CDS SPCG_1303 NC_010582.1 1286916 1287233 R hypothetical protein complement(1286916..1287233) Streptococcus pneumoniae CGSP14 6216569 YP_001836021.1 CDS SPCG_1304 NC_010582.1 1287226 1287510 R hypothetical protein complement(1287226..1287510) Streptococcus pneumoniae CGSP14 6216974 YP_001836022.1 CDS SPCG_1305 NC_010582.1 1287585 1293818 R SNF2 family protein complement(1287585..1293818) Streptococcus pneumoniae CGSP14 6216480 YP_001836023.1 CDS SPCG_1306 NC_010582.1 1293851 1294261 R hypothetical protein complement(1293851..1294261) Streptococcus pneumoniae CGSP14 6216491 YP_001836024.1 CDS SPCG_1307 NC_010582.1 1294413 1295108 R hypothetical protein complement(1294413..1295108) Streptococcus pneumoniae CGSP14 6217030 YP_001836025.1 CDS SPCG_1308 NC_010582.1 1295217 1298030 R hypothetical protein complement(1295217..1298030) Streptococcus pneumoniae CGSP14 6217029 YP_001836026.1 CDS SPCG_1309 NC_010582.1 1298042 1300357 R hypothetical protein complement(1298042..1300357) Streptococcus pneumoniae CGSP14 6216883 YP_001836027.1 CDS SPCG_1310 NC_010582.1 1300347 1300709 R hypothetical protein complement(1300347..1300709) Streptococcus pneumoniae CGSP14 6216921 YP_001836028.1 CDS SPCG_1311 NC_010582.1 1300763 1301617 R hypothetical protein complement(1300763..1301617) Streptococcus pneumoniae CGSP14 6216778 YP_001836029.1 CDS SPCG_1312 NC_010582.1 1301634 1301876 R hypothetical protein complement(1301634..1301876) Streptococcus pneumoniae CGSP14 6216920 YP_001836030.1 CDS SPCG_1313 NC_010582.1 1301897 1303777 R hypothetical protein complement(1301897..1303777) Streptococcus pneumoniae CGSP14 6216847 YP_001836031.1 CDS SPCG_1314 NC_010582.1 1303774 1304283 R hypothetical protein complement(1303774..1304283) Streptococcus pneumoniae CGSP14 6217016 YP_001836032.1 CDS SPCG_1315 NC_010582.1 1304252 1304551 R hypothetical protein complement(1304252..1304551) Streptococcus pneumoniae CGSP14 6216514 YP_001836033.1 CDS SPCG_1316 NC_010582.1 1304834 1305670 R hypothetical protein complement(1304834..1305670) Streptococcus pneumoniae CGSP14 6216959 YP_001836034.1 CDS SPCG_1317 NC_010582.1 1305670 1306314 R hypothetical protein complement(1305670..1306314) Streptococcus pneumoniae CGSP14 6216555 YP_001836035.1 CDS SPCG_1318 NC_010582.1 1306549 1306668 D hypothetical protein 1306549..1306668 Streptococcus pneumoniae CGSP14 6217263 YP_001836036.1 CDS SPCG_1319 NC_010582.1 1306691 1307005 D hypothetical protein 1306691..1307005 Streptococcus pneumoniae CGSP14 6216675 YP_001836037.1 CDS SPCG_1320 NC_010582.1 1307021 1307407 D hypothetical protein 1307021..1307407 Streptococcus pneumoniae CGSP14 6216529 YP_001836038.1 CDS SPCG_1321 NC_010582.1 1307436 1308821 D hypothetical protein 1307436..1308821 Streptococcus pneumoniae CGSP14 6216663 YP_001836039.1 CDS SPCG_1322 NC_010582.1 1308999 1310417 D hypothetical protein 1308999..1310417 Streptococcus pneumoniae CGSP14 6216441 YP_001836040.1 CDS SPCG_1323 NC_010582.1 1310674 1311459 D erythromycin ribosome methylase 1310674..1311459 Streptococcus pneumoniae CGSP14 6216510 YP_001836041.1 CDS SPCG_1324 NC_010582.1 1311797 1312339 D streptothricin acetyltransferase 1311797..1312339 Streptococcus pneumoniae CGSP14 6216454 YP_001836042.1 CDS SPCG_1325 NC_010582.1 1312432 1313226 D aminoglycoside phosphotransferase type III 1312432..1313226 Streptococcus pneumoniae CGSP14 6217078 YP_001836043.1 CDS SPCG_1326 NC_010582.1 1314404 1314643 D omega2 protein 1314404..1314643 Streptococcus pneumoniae CGSP14 6217077 YP_001836044.1 CDS SPCG_1327 NC_010582.1 1314900 1315637 D rRNA methylase 1314900..1315637 Streptococcus pneumoniae CGSP14 6217136 YP_001836045.1 CDS SPCG_1328 NC_010582.1 1315992 1316546 D resolvase 1315992..1316546 Streptococcus pneumoniae CGSP14 6217137 YP_001836046.1 CDS SPCG_1329 NC_010582.1 1316550 1319468 D transposase 1316550..1319468 Streptococcus pneumoniae CGSP14 6216505 YP_001836047.1 CDS SPCG_1330 NC_010582.1 1319524 1319763 R hypothetical protein complement(1319524..1319763) Streptococcus pneumoniae CGSP14 6218504 YP_001836048.1 CDS SPCG_1331 NC_010582.1 1320259 1320690 D hypothetical protein 1320259..1320690 Streptococcus pneumoniae CGSP14 6218531 YP_001836049.1 CDS SPCG_1332 NC_010582.1 1320687 1320917 D hypothetical protein 1320687..1320917 Streptococcus pneumoniae CGSP14 6218506 YP_001836050.1 CDS SPCG_1333 NC_010582.1 1321378 1321581 D hypothetical protein 1321378..1321581 Streptococcus pneumoniae CGSP14 6218526 YP_001836051.1 CDS SPCG_1334 NC_010582.1 1321663 1322625 D hypothetical protein 1321663..1322625 Streptococcus pneumoniae CGSP14 6216346 YP_001836052.1 CDS SPCG_1335 NC_010582.1 1322622 1322879 D hypothetical protein 1322622..1322879 Streptococcus pneumoniae CGSP14 6216336 YP_001836053.1 CDS SPCG_1336 NC_010582.1 1323094 1323681 R hypothetical protein complement(1323094..1323681) Streptococcus pneumoniae CGSP14 6216414 YP_001836054.1 CDS SPCG_1337 NC_010582.1 1323684 1323917 R hypothetical protein complement(1323684..1323917) Streptococcus pneumoniae CGSP14 6218536 YP_001836055.1 CDS SPCG_1338 NC_010582.1 1324303 1324752 R hypothetical protein complement(1324303..1324752) Streptococcus pneumoniae CGSP14 6218537 YP_001836056.1 CDS SPCG_1339 NC_010582.1 1324736 1326094 R type II DNA modification methyltransferase Spn5252IP complement(1324736..1326094) Streptococcus pneumoniae CGSP14 6218492 YP_001836057.1 CDS SPCG_1340 NC_010582.1 1326193 1326972 R replication initiator A, N-terminal complement(1326193..1326972) Streptococcus pneumoniae CGSP14 6218447 YP_001836058.1 CDS SPCG_1341 NC_010582.1 1326969 1327142 R hypothetical protein complement(1326969..1327142) Streptococcus pneumoniae CGSP14 6218424 YP_001836059.1 CDS SPCG_1342 NC_010582.1 1327118 1327264 D hypothetical protein 1327118..1327264 Streptococcus pneumoniae CGSP14 6216898 YP_001836060.1 CDS rplL NC_010582.1 1327330 1327731 D 50S ribosomal protein L7/L12 1327330..1327731 Streptococcus pneumoniae CGSP14 6218576 YP_001836061.1 CDS rplJ NC_010582.1 1327788 1328351 R binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 complement(1327788..1328351) Streptococcus pneumoniae CGSP14 6218422 YP_001836062.1 CDS trzA NC_010582.1 1328538 1330004 R chlorohydrolase complement(1328538..1330004) Streptococcus pneumoniae CGSP14 6216603 YP_001836063.1 CDS SPCG_1346 NC_010582.1 1330099 1331886 R ABC transporter ATP-binding protein/permease complement(1330099..1331886) Streptococcus pneumoniae CGSP14 6217777 YP_001836064.1 CDS SPCG_1347 NC_010582.1 1331849 1333573 R ABC transporter ATP-binding protein/permease complement(1331849..1333573) Streptococcus pneumoniae CGSP14 6218596 YP_001836065.1 CDS msrA NC_010582.1 1333631 1334569 R bifunctional methionine sulfoxide reductase A/B complement(1333631..1334569) Streptococcus pneumoniae CGSP14 6217516 YP_001836066.1 CDS thrB NC_010582.1 1334864 1335733 R catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate; homoserine kinase complement(1334864..1335733) Streptococcus pneumoniae CGSP14 6217276 YP_001836067.1 CDS hom NC_010582.1 1335735 1337054 R catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; homoserine dehydrogenase complement(1335735..1337054) Streptococcus pneumoniae CGSP14 6216328 YP_001836068.1 CDS mecA NC_010582.1 1337172 1337924 R enables recognition and targeting of proteins for proteolysis, involved in negative regulation of competence; adaptor protein complement(1337172..1337924) Streptococcus pneumoniae CGSP14 6216329 YP_001836069.1 CDS SPCG_1352 NC_010582.1 1338051 1339085 R hypothetical protein complement(1338051..1339085) Streptococcus pneumoniae CGSP14 6216604 YP_001836070.1 CDS SPCG_1353 NC_010582.1 1339114 1340547 R hypothetical protein complement(1339114..1340547) Streptococcus pneumoniae CGSP14 6217590 YP_001836071.1 CDS SPCG_1354 NC_010582.1 1340563 1341549 R glycosyl transferase family protein complement(1340563..1341549) Streptococcus pneumoniae CGSP14 6216476 YP_001836072.1 CDS SPCG_1355 NC_010582.1 1341551 1342654 R group 1 glycosyl transferase complement(1341551..1342654) Streptococcus pneumoniae CGSP14 6218340 YP_001836073.1 CDS licD3 NC_010582.1 1342644 1343489 R licD3 protein complement(1342644..1343489) Streptococcus pneumoniae CGSP14 6218475 YP_001836074.1 CDS SPCG_1357 NC_010582.1 1343540 1343650 R hypothetical protein complement(1343540..1343650) Streptococcus pneumoniae CGSP14 6218555 YP_001836075.1 CDS SPCG_1358 NC_010582.1 1343768 1345042 R psr protein complement(1343768..1345042) Streptococcus pneumoniae CGSP14 6218030 YP_001836076.1 CDS pheA NC_010582.1 1345039 1345887 R catalyzes the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis; prephenate dehydratase complement(1345039..1345887) Streptococcus pneumoniae CGSP14 6216952 YP_001836077.1 CDS aroK NC_010582.1 1345884 1346360 R shikimate kinase complement(1345884..1346360) Streptococcus pneumoniae CGSP14 6218287 YP_001836078.1 CDS aroA NC_010582.1 1346353 1347648 R catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis; 3-phosphoshikimate 1-carboxyvinyltransferase complement(1346353..1347648) Streptococcus pneumoniae CGSP14 6218312 YP_001836079.1 CDS SPCG_1362 NC_010582.1 1347728 1348066 R hypothetical protein complement(1347728..1348066) Streptococcus pneumoniae CGSP14 6216377 YP_001836080.1 CDS tyrA NC_010582.1 1348077 1349180 R catalyzes the formation of 4-hydroxyphenylpyruvate from prephenate; prephenate dehydrogenase complement(1348077..1349180) Streptococcus pneumoniae CGSP14 6216335 YP_001836081.1 CDS aroC NC_010582.1 1349190 1350356 R catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis; chorismate synthase complement(1349190..1350356) Streptococcus pneumoniae CGSP14 6216406 YP_001836082.1 CDS aroB NC_010582.1 1350366 1351433 R catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis; 3-dehydroquinate synthase complement(1350366..1351433) Streptococcus pneumoniae CGSP14 6216411 YP_001836083.1 CDS aroE NC_010582.1 1351452 1352306 R AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate; shikimate 5-dehydrogenase complement(1351452..1352306) Streptococcus pneumoniae CGSP14 6216396 YP_001836084.1 CDS aroD NC_010582.1 1352296 1352973 R catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis; 3-dehydroquinate dehydratase complement(1352296..1352973) Streptococcus pneumoniae CGSP14 6216425 YP_001836085.1 CDS SPCG_1368 NC_010582.1 1352970 1354142 R hypothetical protein complement(1352970..1354142) Streptococcus pneumoniae CGSP14 6218552 YP_001836086.1 CDS SPCG_1369 NC_010582.1 1354820 1356481 R hypothetical protein complement(1354820..1356481) Streptococcus pneumoniae CGSP14 6218539 YP_001836087.1 CDS SPCG_1370 NC_010582.1 1356435 1357250 R ABC transporter ATP-binding protein complement(1356435..1357250) Streptococcus pneumoniae CGSP14 6218574 YP_001836088.1 CDS amy NC_010582.1 1357363 1358817 D converts 1,4-alpha-D-glucans to maltodextrin; alpha-amylase 1357363..1358817 Streptococcus pneumoniae CGSP14 6218550 YP_001836089.1 CDS alaS NC_010582.1 1358907 1361525 R Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase complement(1358907..1361525) Streptococcus pneumoniae CGSP14 6218578 YP_001836090.1 CDS SPCG_1373 NC_010582.1 1361547 1362044 R hypothetical protein complement(1361547..1362044) Streptococcus pneumoniae CGSP14 6218011 YP_001836091.1 CDS SPCG_1374 NC_010582.1 1362698 1363768 R spermidine/putrescine ABC transporter spermidine/putrescine-binding protein complement(1362698..1363768) Streptococcus pneumoniae CGSP14 6218502 YP_001836092.1 CDS SPCG_1375 NC_010582.1 1363765 1364565 R spermidine/putrescine ABC transporter permease complement(1363765..1364565) Streptococcus pneumoniae CGSP14 6218494 YP_001836093.1 CDS SPCG_1376 NC_010582.1 1364535 1365362 R spermidine/putrescine ABC transporter permease complement(1364535..1365362) Streptococcus pneumoniae CGSP14 6218392 YP_001836094.1 CDS SPCG_1377 NC_010582.1 1365322 1366479 R spermidine/putrescine ABC transporter ATP-binding protein complement(1365322..1366479) Streptococcus pneumoniae CGSP14 6216360 YP_001836095.1 CDS murB NC_010582.1 1366639 1367544 R catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase complement(1366639..1367544) Streptococcus pneumoniae CGSP14 6217473 YP_001836096.1 CDS SPCG_1379 NC_010582.1 1367596 1367694 D hypothetical protein 1367596..1367694 Streptococcus pneumoniae CGSP14 6216470 YP_001836097.1 CDS SPCG_1380 NC_010582.1 1367658 1368410 R hypothetical protein complement(1367658..1368410) Streptococcus pneumoniae CGSP14 6216332 YP_001836098.1 CDS aldB NC_010582.1 1368420 1369151 R alpha-acetolactate decarboxylase complement(1368420..1369151) Streptococcus pneumoniae CGSP14 6218382 YP_001836099.1 CDS SPCG_1382 NC_010582.1 1369293 1370564 D hypothetical protein 1369293..1370564 Streptococcus pneumoniae CGSP14 6218430 YP_001836100.1 CDS SPCG_1383 NC_010582.1 1370584 1371399 R amino acid ABC transporter amino acid-binding protein complement(1370584..1371399) Streptococcus pneumoniae CGSP14 6218421 YP_001836101.1 CDS SPCG_1384 NC_010582.1 1371556 1372209 R phosphate transport system regulatory protein PhoU complement(1371556..1372209) Streptococcus pneumoniae CGSP14 6218495 YP_001836102.1 CDS SPCG_1385 NC_010582.1 1372221 1372979 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1372221..1372979) Streptococcus pneumoniae CGSP14 6218472 YP_001836103.1 CDS SPCG_1386 NC_010582.1 1372992 1373795 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein complement(1372992..1373795) Streptococcus pneumoniae CGSP14 6218478 YP_001836104.1 CDS SPCG_1387 NC_010582.1 1373806 1374690 R phosphate ABC transporter permease complement(1373806..1374690) Streptococcus pneumoniae CGSP14 6218477 YP_001836105.1 CDS SPCG_1388 NC_010582.1 1374680 1375597 R phosphate ABC transporter permease complement(1374680..1375597) Streptococcus pneumoniae CGSP14 6218499 YP_001836106.1 CDS SPCG_1389 NC_010582.1 1375597 1376475 R phosphate ABC transporter substrate-binding protein complement(1375597..1376475) Streptococcus pneumoniae CGSP14 6218273 YP_001836107.1 CDS SPCG_1390 NC_010582.1 1377049 1378353 R NOL1/NOP2/sun family protein complement(1377049..1378353) Streptococcus pneumoniae CGSP14 6216434 YP_001836108.1 CDS SPCG_1391 NC_010582.1 1378354 1379127 R inositol monophosphatase family protein complement(1378354..1379127) Streptococcus pneumoniae CGSP14 6216969 YP_001836109.1 CDS SPCG_1392 NC_010582.1 1379117 1379395 R hypothetical protein complement(1379117..1379395) Streptococcus pneumoniae CGSP14 6216325 YP_001836110.1 CDS spxA NC_010582.1 1379395 1379796 R the anti-alpha factor Spx interacts with RNA polymerase alpha subunit C-terminal domain in a region that interacts with the sigma 70 subunit and may interfere with activation of promoters; in Bacillus subtilis this protein is a substrate for ClpXP protease; blocks transcription of the competence regulatory gene encoded by the srf operon; regulates a number of genes involved in thiol homeostasis including trxA and trxB; monomeric member of ArsC family of proteins; does not bind DNA; contains a disulfide bond between C10 and C13 which may sense disulfide stress; transcriptional regulator Spx complement(1379395..1379796) Streptococcus pneumoniae CGSP14 6218582 YP_001836111.1 CDS SPCG_1394 NC_010582.1 1380006 1380656 R hypothetical protein complement(1380006..1380656) Streptococcus pneumoniae CGSP14 6217687 YP_001836112.1 CDS SPCG_1395 NC_010582.1 1380613 1381386 R HAD superfamily hydrolase complement(1380613..1381386) Streptococcus pneumoniae CGSP14 6216944 YP_001836113.1 CDS SPCG_1396 NC_010582.1 1381397 1382134 R acyl-ACP thioesterase complement(1381397..1382134) Streptococcus pneumoniae CGSP14 6218454 YP_001836114.1 CDS hemN NC_010582.1 1382139 1383269 R catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; coproporphyrinogen III oxidase complement(1382139..1383269) Streptococcus pneumoniae CGSP14 6218458 YP_001836115.1 CDS SPCG_1398 NC_010582.1 1383353 1383742 R hypothetical protein complement(1383353..1383742) Streptococcus pneumoniae CGSP14 6218456 YP_001836116.1 CDS SPCG_1399 NC_010582.1 1383758 1384141 R hypothetical protein complement(1383758..1384141) Streptococcus pneumoniae CGSP14 6218412 YP_001836117.1 CDS lgt NC_010582.1 1384142 1384942 R transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase complement(1384142..1384942) Streptococcus pneumoniae CGSP14 6218459 YP_001836118.1 CDS hprK NC_010582.1 1384923 1385873 R catalyzes the phosphorylation of the phosphocarrier protein HPr of the bacterial phosphotransferase system; HPr kinase/phosphorylase complement(1384923..1385873) Streptococcus pneumoniae CGSP14 6218462 YP_001836119.1 CDS rpsU NC_010582.1 1385988 1386188 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(1385988..1386188) Streptococcus pneumoniae CGSP14 6218100 YP_001836120.1 CDS nagB NC_010582.1 1386304 1387026 R glucosamine-6-phosphate isomerase complement(1386304..1387026) Streptococcus pneumoniae CGSP14 6218481 YP_001836121.1 CDS queA NC_010582.1 1387150 1388190 D Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step; S-adenosylmethionine--tRNA ribosyltransferase-isomerase 1387150..1388190 Streptococcus pneumoniae CGSP14 6217772 YP_001836122.1 CDS SPCG_1405 NC_010582.1 1388851 1389240 R choline binding protein complement(1388851..1389240) Streptococcus pneumoniae CGSP14 6217778 YP_001836123.1 CDS SPCG_1406 NC_010582.1 1390701 1391252 R acetyltransferase complement(1390701..1391252) Streptococcus pneumoniae CGSP14 6218338 YP_001836124.1 CDS nadE NC_010582.1 1391602 1392426 R catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers; NAD synthetase complement(1391602..1392426) Streptococcus pneumoniae CGSP14 6217773 YP_001836125.1 CDS SPCG_1408 NC_010582.1 1392423 1393883 R catalyzes the formation of 5-phospho-alpha-D-ribose 1-diphosphate and nicotinate from nicotinate D-ribonucleotide and diphosphate; nicotinate phosphoribosyltransferase complement(1392423..1393883) Streptococcus pneumoniae CGSP14 6218107 YP_001836126.1 CDS SPCG_1409 NC_010582.1 1393999 1394487 R hypothetical protein complement(1393999..1394487) Streptococcus pneumoniae CGSP14 6217776 YP_001836127.1 CDS SPCG_1410 NC_010582.1 1395150 1395551 R hypothetical protein complement(1395150..1395551) Streptococcus pneumoniae CGSP14 6218514 YP_001836128.1 CDS SPCG_1411 NC_010582.1 1395567 1395701 R hypothetical protein complement(1395567..1395701) Streptococcus pneumoniae CGSP14 6217559 YP_001836129.1 CDS SPCG_1412 NC_010582.1 1395711 1396031 R hypothetical protein complement(1395711..1396031) Streptococcus pneumoniae CGSP14 6217314 YP_001836130.1 CDS SPCG_1413 NC_010582.1 1396041 1396289 R hypothetical protein complement(1396041..1396289) Streptococcus pneumoniae CGSP14 6218426 YP_001836131.1 CDS SPCG_1414 NC_010582.1 1396792 1397517 R U32 family peptidase complement(1396792..1397517) Streptococcus pneumoniae CGSP14 6218419 YP_001836132.1 CDS SPCG_1415 NC_010582.1 1397670 1397837 D hypothetical protein 1397670..1397837 Streptococcus pneumoniae CGSP14 6218418 YP_001836133.1 CDS SPCG_1416 NC_010582.1 1398092 1399396 R U32 family peptidase complement(1398092..1399396) Streptococcus pneumoniae CGSP14 6218529 YP_001836134.1 CDS SPCG_1417 NC_010582.1 1400002 1400184 D hypothetical protein 1400002..1400184 Streptococcus pneumoniae CGSP14 6216370 YP_001836135.1 CDS SPCG_1418 NC_010582.1 1400368 1400556 D hypothetical protein 1400368..1400556 Streptococcus pneumoniae CGSP14 6217691 YP_001836136.1 CDS SPCG_1419 NC_010582.1 1400553 1401743 D type II DNA modification methyltransferase 1400553..1401743 Streptococcus pneumoniae CGSP14 6217482 YP_001836137.1 CDS SPCG_1420 NC_010582.1 1401990 1402136 D hypothetical protein 1401990..1402136 Streptococcus pneumoniae CGSP14 6216562 YP_001836138.1 CDS SPCG_1421 NC_010582.1 1402258 1403250 R AraC family transcriptional regulator complement(1402258..1403250) Streptococcus pneumoniae CGSP14 6216695 YP_001836139.1 CDS SPCG_1422 NC_010582.1 1403404 1405164 D ABC transporter ATP-binding protein/permease 1403404..1405164 Streptococcus pneumoniae CGSP14 6216791 YP_001836140.1 CDS SPCG_1423 NC_010582.1 1405124 1406869 D ABC transporter ATP-binding protein 1405124..1406869 Streptococcus pneumoniae CGSP14 6216994 YP_001836141.1 CDS SPCG_1424 NC_010582.1 1406880 1407509 D hypothetical protein 1406880..1407509 Streptococcus pneumoniae CGSP14 6216941 YP_001836142.1 CDS SPCG_1425 NC_010582.1 1407458 1407967 D hypothetical protein 1407458..1407967 Streptococcus pneumoniae CGSP14 6216636 YP_001836143.1 CDS SPCG_1426 NC_010582.1 1407955 1409319 D ABC transporter ATP-binding protein 1407955..1409319 Streptococcus pneumoniae CGSP14 6217068 YP_001836144.1 CDS SPCG_1427 NC_010582.1 1410250 1410546 R hypothetical protein complement(1410250..1410546) Streptococcus pneumoniae CGSP14 6216632 YP_001836145.1 CDS SPCG_1428 NC_010582.1 1410619 1410903 R hypothetical protein complement(1410619..1410903) Streptococcus pneumoniae CGSP14 6218111 YP_001836146.1 CDS SPCG_1429 NC_010582.1 1410950 1411156 R hypothetical protein complement(1410950..1411156) Streptococcus pneumoniae CGSP14 6216744 YP_001836147.1 CDS SPCG_1430 NC_010582.1 1411320 1411514 R hypothetical protein complement(1411320..1411514) Streptococcus pneumoniae CGSP14 6217435 YP_001836148.1 CDS SPCG_1431 NC_010582.1 1411833 1412069 R hypothetical protein complement(1411833..1412069) Streptococcus pneumoniae CGSP14 6218029 YP_001836149.1 CDS SPCG_1432 NC_010582.1 1412050 1412289 R IS66 family Orf1 complement(1412050..1412289) Streptococcus pneumoniae CGSP14 6216864 YP_001836150.1 CDS guaA NC_010582.1 1412539 1414101 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1412539..1414101) Streptococcus pneumoniae CGSP14 6217574 YP_001836151.1 CDS SPCG_1434 NC_010582.1 1414234 1414941 D GntR family transcriptional regulator 1414234..1414941 Streptococcus pneumoniae CGSP14 6216567 YP_001836152.1 CDS SPCG_1435 NC_010582.1 1414984 1415940 R membrane protein complement(1414984..1415940) Streptococcus pneumoniae CGSP14 6218187 YP_001836153.1 CDS SPCG_1436 NC_010582.1 1415889 1416824 R hypothetical protein complement(1415889..1416824) Streptococcus pneumoniae CGSP14 6218026 YP_001836154.1 CDS cppA NC_010582.1 1416821 1417561 R cppA protein complement(1416821..1417561) Streptococcus pneumoniae CGSP14 6217475 YP_001836155.1 CDS SPCG_1438 NC_010582.1 1417630 1418265 R platelet activating factor complement(1417630..1418265) Streptococcus pneumoniae CGSP14 6218236 YP_001836156.1 CDS SPCG_1439 NC_010582.1 1418267 1419094 R cof family protein complement(1418267..1419094) Streptococcus pneumoniae CGSP14 6217923 YP_001836157.1 CDS SPCG_1440 NC_010582.1 1419116 1419451 R hypothetical protein complement(1419116..1419451) Streptococcus pneumoniae CGSP14 6217368 YP_001836158.1 CDS SPCG_1441 NC_010582.1 1419452 1419964 R hypothetical protein complement(1419452..1419964) Streptococcus pneumoniae CGSP14 6217499 YP_001836159.1 CDS SPCG_1442 NC_010582.1 1420058 1420180 R hypothetical protein complement(1420058..1420180) Streptococcus pneumoniae CGSP14 6217907 YP_001836160.1 CDS def NC_010582.1 1420692 1421303 D cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase 1420692..1421303 Streptococcus pneumoniae CGSP14 6217864 YP_001836161.1 CDS trmH NC_010582.1 1421315 1422076 D spoU rRNA methylase family protein 1421315..1422076 Streptococcus pneumoniae CGSP14 6218013 YP_001836162.1 CDS trxB NC_010582.1 1422115 1423026 R thioredoxin reductase complement(1422115..1423026) Streptococcus pneumoniae CGSP14 6218129 YP_001836163.1 CDS SPCG_1446 NC_010582.1 1423092 1423328 R hypothetical protein complement(1423092..1423328) Streptococcus pneumoniae CGSP14 6217386 YP_001836164.1 CDS SPCG_1447 NC_010582.1 1423394 1424137 R amino acid ABC transporter ATP-binding protein complement(1423394..1424137) Streptococcus pneumoniae CGSP14 6217769 YP_001836165.1 CDS SPCG_1448 NC_010582.1 1424137 1424937 R amino acid ABC transporter permease complement(1424137..1424937) Streptococcus pneumoniae CGSP14 6217480 YP_001836166.1 CDS SPCG_1449 NC_010582.1 1425095 1425451 R hypothetical protein complement(1425095..1425451) Streptococcus pneumoniae CGSP14 6218105 YP_001836167.1 CDS ogt NC_010582.1 1425464 1425976 R methylated-DNA--protein-cysteine S-methyltransferase complement(1425464..1425976) Streptococcus pneumoniae CGSP14 6218482 YP_001836168.1 CDS SPCG_1451 NC_010582.1 1425976 1426470 R acetyltransferase complement(1425976..1426470) Streptococcus pneumoniae CGSP14 6217963 YP_001836169.1 CDS SPCG_1452 NC_010582.1 1426599 1427051 D hypothetical protein 1426599..1427051 Streptococcus pneumoniae CGSP14 6216532 YP_001836170.1 CDS SPCG_1453 NC_010582.1 1427048 1427695 D hemolysin 1427048..1427695 Streptococcus pneumoniae CGSP14 6217118 YP_001836171.1 CDS SPCG_1454 NC_010582.1 1428047 1429363 R hypothetical protein complement(1428047..1429363) Streptococcus pneumoniae CGSP14 6218202 YP_001836172.1 CDS SPCG_1455 NC_010582.1 1429381 1430181 R ABC transporter ATP-binding protein complement(1429381..1430181) Streptococcus pneumoniae CGSP14 6217558 YP_001836173.1 CDS SPCG_1456 NC_010582.1 1430669 1431253 R with PdxST is involved in the biosynthesis of pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of glutamine to glutamate and ammonia; PdxS utilizes the ammonia to synthesize pyridoxal 5'-phosphate; glutamine amidotransferase subunit PdxT complement(1430669..1431253) Streptococcus pneumoniae CGSP14 6217449 YP_001836174.1 CDS pdx1 NC_010582.1 1431254 1432147 R with PdxT forms pyridoxal 5'-phosphate from glutamine, either ribose 5-phosphate or ribulose 5-phosphate, and either glyceraldehyde 3-phosphate or dihydroxyacetone phosphate; pyridoxal biosynthesis lyase PdxS complement(1431254..1432147) Streptococcus pneumoniae CGSP14 6218295 YP_001836175.1 CDS nox NC_010582.1 1432281 1433660 R NADH oxidase complement(1432281..1433660) Streptococcus pneumoniae CGSP14 6216649 YP_001836176.1 CDS apbE NC_010582.1 1433954 1434877 D thiamine biosynthesis protein ApbE 1433954..1434877 Streptococcus pneumoniae CGSP14 6216455 YP_001836177.1 CDS SPCG_1460 NC_010582.1 1434937 1435542 D oxidoreductase 1434937..1435542 Streptococcus pneumoniae CGSP14 6218061 YP_001836178.1 CDS SPCG_1461 NC_010582.1 1435561 1436805 D oxidoreductase 1435561..1436805 Streptococcus pneumoniae CGSP14 6217628 YP_001836179.1 CDS SPCG_1462 NC_010582.1 1437028 1437285 R hypothetical protein complement(1437028..1437285) Streptococcus pneumoniae CGSP14 6217852 YP_001836180.1 CDS glyS NC_010582.1 1437327 1439363 R glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit beta complement(1437327..1439363) Streptococcus pneumoniae CGSP14 6217052 YP_001836181.1 CDS glyQ NC_010582.1 1439649 1440566 R glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha complement(1439649..1440566) Streptococcus pneumoniae CGSP14 6217272 YP_001836182.1 CDS SPCG_1465 NC_010582.1 1440758 1441537 R hypothetical protein complement(1440758..1441537) Streptococcus pneumoniae CGSP14 6217275 YP_001836183.1 CDS SPCG_1466 NC_010582.1 1441792 1442634 R aldo/keto reductase family oxidoreductase complement(1441792..1442634) Streptococcus pneumoniae CGSP14 6217751 YP_001836184.1 CDS pgdA NC_010582.1 1442748 1444190 R peptidoglycan N-acetylglucosamine deacetylase A complement(1442748..1444190) Streptococcus pneumoniae CGSP14 6217943 YP_001836185.1 CDS SPCG_1468 NC_010582.1 1444374 1444751 R hypothetical protein complement(1444374..1444751) Streptococcus pneumoniae CGSP14 6216787 YP_001836186.1 CDS mocA NC_010582.1 1444771 1445853 D Gfo/Idh/MocA family oxidoreductase 1444771..1445853 Streptococcus pneumoniae CGSP14 6217583 YP_001836187.1 CDS SPCG_1470 NC_010582.1 1445850 1446932 D DEAD/DEAH box helicase 1445850..1446932 Streptococcus pneumoniae CGSP14 6217939 YP_001836188.1 CDS SPCG_1471 NC_010582.1 1446996 1447262 R hypothetical protein complement(1446996..1447262) Streptococcus pneumoniae CGSP14 6217312 YP_001836189.1 CDS SPCG_1472 NC_010582.1 1447527 1447634 R hypothetical protein complement(1447527..1447634) Streptococcus pneumoniae CGSP14 6217660 YP_001836190.1 CDS SPCG_1473 NC_010582.1 1447886 1448017 R hypothetical protein complement(1447886..1448017) Streptococcus pneumoniae CGSP14 6217564 YP_001836191.1 CDS tuf NC_010582.1 1448401 1449615 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(1448401..1449615) Streptococcus pneumoniae CGSP14 6217654 YP_001836192.1 CDS glpF NC_010582.1 1450530 1451399 R glycerol uptake facilitator protein complement(1450530..1451399) Streptococcus pneumoniae CGSP14 6218257 YP_001836193.1 CDS SPCG_1476 NC_010582.1 1451622 1451783 R cell wall surface anchor family protein complement(1451622..1451783) Streptococcus pneumoniae CGSP14 6217674 YP_001836194.1 CDS SPCG_1477 NC_010582.1 1452100 1453212 R hypothetical protein complement(1452100..1453212) Streptococcus pneumoniae CGSP14 6216656 YP_001836195.1 CDS SPCG_1478 NC_010582.1 1453850 1453945 R hypothetical protein complement(1453850..1453945) Streptococcus pneumoniae CGSP14 6217739 YP_001836196.1 CDS SPCG_1479 NC_010582.1 1453911 1454210 R transposase, IS630-Spn1 related, Orf2 complement(1453911..1454210) Streptococcus pneumoniae CGSP14 6217025 YP_001836197.1 CDS SPCG_1480 NC_010582.1 1454430 1454645 R hypothetical protein complement(1454430..1454645) Streptococcus pneumoniae CGSP14 6217502 YP_001836198.1 CDS pgm NC_010582.1 1454989 1456707 D phosphoglucomutase 1454989..1456707 Streptococcus pneumoniae CGSP14 6217664 YP_001836199.1 CDS SPCG_1482 NC_010582.1 1456757 1457284 R degenerate transposase complement(1456757..1457284) Streptococcus pneumoniae CGSP14 6217243 YP_001836200.1 CDS SPCG_1483 NC_010582.1 1457565 1458083 R degenerate transposase complement(1457565..1458083) Streptococcus pneumoniae CGSP14 6216450 YP_001836201.1 CDS bta NC_010582.1 1458310 1458657 D bacterocin transport accessory protein 1458310..1458657 Streptococcus pneumoniae CGSP14 6216407 YP_001836202.1 CDS SPCG_1485 NC_010582.1 1458937 1459773 R amino acid ABC transporter amino acid-binding protein complement(1458937..1459773) Streptococcus pneumoniae CGSP14 6217613 YP_001836203.1 CDS SPCG_1486 NC_010582.1 1459786 1460415 R amino acid ABC transporter ATP-binding protein complement(1459786..1460415) Streptococcus pneumoniae CGSP14 6218010 YP_001836204.1 CDS SPCG_1487 NC_010582.1 1460425 1461123 R amino acid ABC transporter permease complement(1460425..1461123) Streptococcus pneumoniae CGSP14 6216685 YP_001836205.1 CDS SPCG_1488 NC_010582.1 1461212 1462456 R hypothetical protein complement(1461212..1462456) Streptococcus pneumoniae CGSP14 6217031 YP_001836206.1 CDS SPCG_1489 NC_010582.1 1462431 1463597 R membrane protein complement(1462431..1463597) Streptococcus pneumoniae CGSP14 6217240 YP_001836207.1 CDS SPCG_1490 NC_010582.1 1463741 1464754 D hypothetical protein 1463741..1464754 Streptococcus pneumoniae CGSP14 6216408 YP_001836208.1 CDS atpC NC_010582.1 1464799 1465218 R part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane; F0F1 ATP synthase subunit epsilon complement(1464799..1465218) Streptococcus pneumoniae CGSP14 6218386 YP_001836209.1 CDS atpD NC_010582.1 1465229 1466635 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit; F0F1 ATP synthase subunit beta complement(1465229..1466635) Streptococcus pneumoniae CGSP14 6217054 YP_001836210.1 CDS atpG NC_010582.1 1466721 1467599 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit; F0F1 ATP synthase subunit gamma complement(1466721..1467599) Streptococcus pneumoniae CGSP14 6216822 YP_001836211.1 CDS atpA NC_010582.1 1467615 1469120 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1467615..1469120) Streptococcus pneumoniae CGSP14 6217652 YP_001836212.1 CDS atpH NC_010582.1 1469135 1469671 R Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex; F0F1 ATP synthase subunit delta complement(1469135..1469671) Streptococcus pneumoniae CGSP14 6218076 YP_001836213.1 CDS atpF NC_010582.1 1469671 1470165 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel.; F0F1 ATP synthase subunit B complement(1469671..1470165) Streptococcus pneumoniae CGSP14 6218281 YP_001836214.1 CDS atpB NC_010582.1 1470179 1470895 R Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A complement(1470179..1470895) Streptococcus pneumoniae CGSP14 6217961 YP_001836215.1 CDS atpE NC_010582.1 1470930 1471130 R produces ATP from ADP in the presence of a proton gradient across the membrane; subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C complement(1470930..1471130) Streptococcus pneumoniae CGSP14 6216578 YP_001836216.1 CDS SPCG_1499 NC_010582.1 1471205 1472257 R IS1239 transposase complement(1471205..1472257) Streptococcus pneumoniae CGSP14 6218017 YP_001836217.1 CDS SPCG_1500 NC_010582.1 1472670 1473152 R acetyltransferase complement(1472670..1473152) Streptococcus pneumoniae CGSP14 6217236 YP_001836218.1 CDS SPCG_1501 NC_010582.1 1473186 1473728 R hypothetical protein complement(1473186..1473728) Streptococcus pneumoniae CGSP14 6217523 YP_001836219.1 CDS greA NC_010582.1 1473756 1474247 R necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus; transcription elongation factor GreA complement(1473756..1474247) Streptococcus pneumoniae CGSP14 6218054 YP_001836220.1 CDS SPCG_1503 NC_010582.1 1474309 1475964 R hypothetical protein complement(1474309..1475964) Streptococcus pneumoniae CGSP14 6217965 YP_001836221.1 CDS SPCG_1504 NC_010582.1 1476045 1476539 R acetyltransferase complement(1476045..1476539) Streptococcus pneumoniae CGSP14 6216525 YP_001836222.1 CDS SPCG_1505 NC_010582.1 1476536 1477000 R acetyltransferase complement(1476536..1477000) Streptococcus pneumoniae CGSP14 6217997 YP_001836223.1 CDS murC NC_010582.1 1477010 1478344 R Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis; UDP-N-acetylmuramate--L-alanine ligase complement(1477010..1478344) Streptococcus pneumoniae CGSP14 6217329 YP_001836224.1 CDS SPCG_1507 NC_010582.1 1478355 1478972 R hypothetical protein complement(1478355..1478972) Streptococcus pneumoniae CGSP14 6218075 YP_001836225.1 CDS snf NC_010582.1 1479020 1482118 R snf2 family protein complement(1479020..1482118) Streptococcus pneumoniae CGSP14 6217996 YP_001836226.1 CDS patB NC_010582.1 1482211 1483377 R class II aminotransferase complement(1482211..1483377) Streptococcus pneumoniae CGSP14 6217707 YP_001836227.1 CDS metB NC_010582.1 1483385 1484479 R catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; cystathionine gamma-synthase complement(1483385..1484479) Streptococcus pneumoniae CGSP14 6217578 YP_001836228.1 CDS SPCG_1511 NC_010582.1 1484636 1485229 R hypothetical protein complement(1484636..1485229) Streptococcus pneumoniae CGSP14 6217569 YP_001836229.1 CDS SPCG_1512 NC_010582.1 1485217 1485756 R hypothetical protein complement(1485217..1485756) Streptococcus pneumoniae CGSP14 6217461 YP_001836230.1 CDS SPCG_1513 NC_010582.1 1485765 1486310 R multidrug ABC transporter ATPase/permease complement(1485765..1486310) Streptococcus pneumoniae CGSP14 6218150 YP_001836231.1 CDS aliB NC_010582.1 1486482 1488440 R oligopeptide ABC transporter oligopeptide-binding protein AliB complement(1486482..1488440) Streptococcus pneumoniae CGSP14 6217989 YP_001836232.1 CDS SPCG_1515 NC_010582.1 1488427 1488522 R hypothetical protein complement(1488427..1488522) Streptococcus pneumoniae CGSP14 6217733 YP_001836233.1 CDS SPCG_1516 NC_010582.1 1488643 1490280 R polysaccharide biosynthesis protein complement(1488643..1490280) Streptococcus pneumoniae CGSP14 6216698 YP_001836234.1 CDS murE NC_010582.1 1490371 1491816 D involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine; UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine ligase 1490371..1491816 Streptococcus pneumoniae CGSP14 6218057 YP_001836235.1 CDS SPCG_1518 NC_010582.1 1492110 1492682 R hypothetical protein complement(1492110..1492682) Streptococcus pneumoniae CGSP14 6217964 YP_001836236.1 CDS SPCG_1519 NC_010582.1 1492719 1493231 R hypothetical protein complement(1492719..1493231) Streptococcus pneumoniae CGSP14 6218560 YP_001836237.1 CDS ppaC NC_010582.1 1493318 1494253 R catalyzes the hydrolysis of pyrophosphate to phosphate; manganese-dependent inorganic pyrophosphatase complement(1493318..1494253) Streptococcus pneumoniae CGSP14 6216754 YP_001836238.1 CDS SPCG_1521 NC_010582.1 1494324 1494623 R hypothetical protein complement(1494324..1494623) Streptococcus pneumoniae CGSP14 6216395 YP_001836239.1 CDS SPCG_1522 NC_010582.1 1494613 1495362 R hypothetical protein complement(1494613..1495362) Streptococcus pneumoniae CGSP14 6216357 YP_001836240.1 CDS SPCG_1523 NC_010582.1 1495416 1495802 R hypothetical protein complement(1495416..1495802) Streptococcus pneumoniae CGSP14 6216337 YP_001836241.1 CDS SPCG_1524 NC_010582.1 1495777 1497177 R cof family protein/peptidyl-prolyl cis-trans isomerase, cyclophilin type complement(1495777..1497177) Streptococcus pneumoniae CGSP14 6216365 YP_001836242.1 CDS rpsR NC_010582.1 1497472 1497711 R binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 complement(1497472..1497711) Streptococcus pneumoniae CGSP14 6217972 YP_001836243.1 CDS ssbA NC_010582.1 1497743 1498213 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1497743..1498213) Streptococcus pneumoniae CGSP14 6217063 YP_001836244.1 CDS rpsF NC_010582.1 1498225 1498515 R binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 complement(1498225..1498515) Streptococcus pneumoniae CGSP14 6218414 YP_001836245.1 CDS asnC NC_010582.1 1498669 1500012 R catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; asparaginyl-tRNA synthetase complement(1498669..1500012) Streptococcus pneumoniae CGSP14 6218391 YP_001836246.1 CDS SPCG_1529 NC_010582.1 1500031 1500402 R hypothetical protein complement(1500031..1500402) Streptococcus pneumoniae CGSP14 6218476 YP_001836247.1 CDS aspB NC_010582.1 1500389 1501576 R catalyzes the formation of oxalozcetate and L-glutamate from L-aspartate and 2-oxoglutarate; aspartate aminotransferase complement(1500389..1501576) Streptococcus pneumoniae CGSP14 6218489 YP_001836248.1 CDS SPCG_1531 NC_010582.1 1501573 1502061 R hypothetical protein complement(1501573..1502061) Streptococcus pneumoniae CGSP14 6218568 YP_001836249.1 CDS SPCG_1532 NC_010582.1 1502301 1502930 D hypothetical protein 1502301..1502930 Streptococcus pneumoniae CGSP14 6216955 YP_001836250.1 CDS SPCG_1533 NC_010582.1 1503208 1503936 R hypothetical protein complement(1503208..1503936) Streptococcus pneumoniae CGSP14 6218522 YP_001836251.1 CDS SPCG_1534 NC_010582.1 1504030 1504194 R hypothetical protein complement(1504030..1504194) Streptococcus pneumoniae CGSP14 6218460 YP_001836252.1 CDS SPCG_1535 NC_010582.1 1504347 1505942 R hypothetical protein complement(1504347..1505942) Streptococcus pneumoniae CGSP14 6218433 YP_001836253.1 CDS def NC_010582.1 1505954 1506364 R cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+); peptide deformylase complement(1505954..1506364) Streptococcus pneumoniae CGSP14 6218503 YP_001836254.1 CDS SPCG_1537 NC_010582.1 1506480 1507271 R YghU; B2989; one of eight glutathione transferase proteins from E. coli; glutathione S-transferase complement(1506480..1507271) Streptococcus pneumoniae CGSP14 6218521 YP_001836255.1 CDS pacL NC_010582.1 1507284 1510028 R cation transporter E1-E2 family ATPase complement(1507284..1510028) Streptococcus pneumoniae CGSP14 6216345 YP_001836256.1 CDS SPCG_1539 NC_010582.1 1510284 1511468 D cation efflux family protein 1510284..1511468 Streptococcus pneumoniae CGSP14 6216343 YP_001836257.1 CDS SPCG_1540 NC_010582.1 1511611 1513482 R ABC transporter ATP-binding protein complement(1511611..1513482) Streptococcus pneumoniae CGSP14 6217521 YP_001836258.1 CDS SPCG_1541 NC_010582.1 1513479 1514678 R catalyzes the addition and repair of the 3'-terminal CCA sequence in tRNA; these proteins belong to the CCA-adding enzyme subfamily 2 which does not have phosphohydrolase activity; tRNA CCA-pyrophosphorylase complement(1513479..1514678) Streptococcus pneumoniae CGSP14 6217438 YP_001836259.1 CDS dapB NC_010582.1 1514675 1515442 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(1514675..1515442) Streptococcus pneumoniae CGSP14 6216436 YP_001836260.1 CDS SPCG_1543 NC_010582.1 1515708 1516556 R degV family protein complement(1515708..1516556) Streptococcus pneumoniae CGSP14 6217710 YP_001836261.1 CDS SPCG_1544 NC_010582.1 1516558 1516944 R hypothetical protein complement(1516558..1516944) Streptococcus pneumoniae CGSP14 6217441 YP_001836262.1 CDS glmM NC_010582.1 1517006 1518358 R catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; phosphoglucosamine mutase complement(1517006..1518358) Streptococcus pneumoniae CGSP14 6216950 YP_001836263.1 CDS SPCG_1546 NC_010582.1 1518382 1519161 R hypothetical protein complement(1518382..1519161) Streptococcus pneumoniae CGSP14 6216706 YP_001836264.1 CDS SPCG_1547 NC_010582.1 1519148 1520026 R hypothetical protein complement(1519148..1520026) Streptococcus pneumoniae CGSP14 6218000 YP_001836265.1 CDS SPCG_1548 NC_010582.1 1520141 1521106 D pyridine nucleotide-disulfide oxidoreductase family protein 1520141..1521106 Streptococcus pneumoniae CGSP14 6217217 YP_001836266.1 CDS SPCG_1549 NC_010582.1 1521140 1522051 R hypothetical protein complement(1521140..1522051) Streptococcus pneumoniae CGSP14 6217597 YP_001836267.1 CDS SPCG_1550 NC_010582.1 1522048 1523025 R hypothetical protein complement(1522048..1523025) Streptococcus pneumoniae CGSP14 6217120 YP_001836268.1 CDS SPCG_1551 NC_010582.1 1523022 1523912 R hypothetical protein complement(1523022..1523912) Streptococcus pneumoniae CGSP14 6217571 YP_001836269.1 CDS SPCG_1552 NC_010582.1 1523964 1524344 R endoribonuclease L-PSP complement(1523964..1524344) Streptococcus pneumoniae CGSP14 6218487 YP_001836270.1 CDS engB NC_010582.1 1524355 1524948 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(1524355..1524948) Streptococcus pneumoniae CGSP14 6217936 YP_001836271.1 CDS clpX NC_010582.1 1524951 1526183 R binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX complement(1524951..1526183) Streptococcus pneumoniae CGSP14 6217969 YP_001836272.1 CDS SPCG_1555 NC_010582.1 1526215 1526385 R hypothetical protein complement(1526215..1526385) Streptococcus pneumoniae CGSP14 6217889 YP_001836273.1 CDS dfr NC_010582.1 1526385 1526891 R dihydrofolate reductase complement(1526385..1526891) Streptococcus pneumoniae CGSP14 6216793 YP_001836274.1 CDS SPCG_1557 NC_010582.1 1527021 1527539 R non-heme iron-containing ferritin complement(1527021..1527539) Streptococcus pneumoniae CGSP14 6216748 YP_001836275.1 CDS SPCG_1558 NC_010582.1 1527752 1527844 D hypothetical protein 1527752..1527844 Streptococcus pneumoniae CGSP14 6216665 YP_001836276.1 CDS lytC NC_010582.1 1528037 1529542 R lysozyme complement(1528037..1529542) Streptococcus pneumoniae CGSP14 6216707 YP_001836277.1 CDS tpiA NC_010582.1 1529580 1530359 R Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase complement(1529580..1530359) Streptococcus pneumoniae CGSP14 6217520 YP_001836278.1 CDS SPCG_1561 NC_010582.1 1530436 1531113 R hypothetical protein complement(1530436..1531113) Streptococcus pneumoniae CGSP14 6217264 YP_001836279.1 CDS metA NC_010582.1 1531122 1532066 R catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis; homoserine O-succinyltransferase complement(1531122..1532066) Streptococcus pneumoniae CGSP14 6216423 YP_001836280.1 CDS apt NC_010582.1 1532248 1532778 R catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis; adenine phosphoribosyltransferase complement(1532248..1532778) Streptococcus pneumoniae CGSP14 6217570 YP_001836281.1 CDS SPCG_1564 NC_010582.1 1532848 1533606 R methyltransferase complement(1532848..1533606) Streptococcus pneumoniae CGSP14 6218497 YP_001836282.1 CDS SPCG_1565 NC_010582.1 1534107 1535237 R sugar ABC transporter ATP-binding protein complement(1534107..1535237) Streptococcus pneumoniae CGSP14 6218593 YP_001836283.1 CDS entB NC_010582.1 1535687 1536262 R isochorismatase family protein complement(1535687..1536262) Streptococcus pneumoniae CGSP14 6216363 YP_001836284.1 CDS codY NC_010582.1 1536262 1537050 R CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase (By similarity). It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; transcriptional repressor CodY complement(1536262..1537050) Streptococcus pneumoniae CGSP14 6218441 YP_001836285.1 CDS SPCG_1568 NC_010582.1 1537315 1538889 R ATP-dependent RNA helicase complement(1537315..1538889) Streptococcus pneumoniae CGSP14 6216369 YP_001836286.1 CDS oxlT NC_010582.1 1539088 1540314 R oxalate:formate antiporter complement(1539088..1540314) Streptococcus pneumoniae CGSP14 6217374 YP_001836287.1 CDS merA NC_010582.1 1540507 1541823 D Involved in disulfide oxidoreductase activity and electron transport; pyridine nucleotide-disulfide oxidoreductase 1540507..1541823 Streptococcus pneumoniae CGSP14 6217834 YP_001836288.1 CDS SPCG_1571 NC_010582.1 1541922 1543265 D mur ligase family protein 1541922..1543265 Streptococcus pneumoniae CGSP14 6218022 YP_001836289.1 CDS SPCG_1572 NC_010582.1 1543265 1544047 D hypothetical protein 1543265..1544047 Streptococcus pneumoniae CGSP14 6217534 YP_001836290.1 CDS SPCG_1573 NC_010582.1 1544173 1545255 D proline dipeptidase 1544173..1545255 Streptococcus pneumoniae CGSP14 6217876 YP_001836291.1 CDS SPCG_1574 NC_010582.1 1545579 1546412 R IS3-Spn1, transposase complement(1545579..1546412) Streptococcus pneumoniae CGSP14 6216324 YP_001836292.1 CDS SPCG_1575 NC_010582.1 1546405 1546572 R degenerate transposase complement(1546405..1546572) Streptococcus pneumoniae CGSP14 6216359 YP_001836293.1 CDS SPCG_1576 NC_010582.1 1547147 1547608 R hypothetical protein complement(1547147..1547608) Streptococcus pneumoniae CGSP14 6216954 YP_001836294.1 CDS pdxK NC_010582.1 1547586 1548359 R catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine; phosphomethylpyrimidine kinase complement(1547586..1548359) Streptococcus pneumoniae CGSP14 6218562 YP_001836295.1 CDS truA NC_010582.1 1548349 1549098 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(1548349..1549098) Streptococcus pneumoniae CGSP14 6218517 YP_001836296.1 CDS SPCG_1579 NC_010582.1 1549278 1549439 D cytidylate kinase 1549278..1549439 Streptococcus pneumoniae CGSP14 6218471 YP_001836297.1 CDS SPCG_1580 NC_010582.1 1549411 1550562 R hypothetical protein complement(1549411..1550562) Streptococcus pneumoniae CGSP14 6218327 YP_001836298.1 CDS SPCG_1581 NC_010582.1 1550802 1551431 R hypothetical protein complement(1550802..1551431) Streptococcus pneumoniae CGSP14 6218505 YP_001836299.1 CDS phnA NC_010582.1 1551434 1551772 R phnA protein complement(1551434..1551772) Streptococcus pneumoniae CGSP14 6216389 YP_001836300.1 CDS cmk NC_010582.1 1551903 1552574 R Catalyzes the formation of (d)CDP from ATP and (d)CMP; cytidylate kinase complement(1551903..1552574) Streptococcus pneumoniae CGSP14 6218166 YP_001836301.1 CDS SPCG_1584 NC_010582.1 1552583 1553059 R hypothetical protein complement(1552583..1553059) Streptococcus pneumoniae CGSP14 6217797 YP_001836302.1 CDS SPCG_1585 NC_010582.1 1553111 1553317 D ferredoxin 1553111..1553317 Streptococcus pneumoniae CGSP14 6218445 YP_001836303.1 CDS SPCG_1586 NC_010582.1 1553507 1554151 R hypothetical protein complement(1553507..1554151) Streptococcus pneumoniae CGSP14 6218448 YP_001836304.1 CDS gtrB NC_010582.1 1554326 1555315 R glycosyl transferase family protein complement(1554326..1555315) Streptococcus pneumoniae CGSP14 6218379 YP_001836305.1 CDS galE NC_010582.1 1555263 1556282 R UDP-glucose 4-epimerase complement(1555263..1556282) Streptococcus pneumoniae CGSP14 6217784 YP_001836306.1 CDS SPCG_1589 NC_010582.1 1556261 1556410 R hypothetical protein complement(1556261..1556410) Streptococcus pneumoniae CGSP14 6216942 YP_001836307.1 CDS SPCG_1590 NC_010582.1 1556583 1557695 R oxidoreductase, DadA family protein complement(1556583..1557695) Streptococcus pneumoniae CGSP14 6218381 YP_001836308.1 CDS SPCG_1591 NC_010582.1 1557703 1558500 R hypothetical protein complement(1557703..1558500) Streptococcus pneumoniae CGSP14 6216323 YP_001836309.1 CDS SPCG_1592 NC_010582.1 1558487 1559164 R bcl-2 family protein complement(1558487..1559164) Streptococcus pneumoniae CGSP14 6218498 YP_001836310.1 CDS SPCG_1593 NC_010582.1 1559522 1559626 D hypothetical protein 1559522..1559626 Streptococcus pneumoniae CGSP14 6216424 YP_001836311.1 CDS SPCG_1594 NC_010582.1 1559713 1560663 D hypothetical protein 1559713..1560663 Streptococcus pneumoniae CGSP14 6216397 YP_001836312.1 CDS SPCG_1595 NC_010582.1 1560771 1562216 D hypothetical protein 1560771..1562216 Streptococcus pneumoniae CGSP14 6217854 YP_001836313.1 CDS SPCG_1596 NC_010582.1 1562218 1563456 D hypothetical protein 1562218..1563456 Streptococcus pneumoniae CGSP14 6217807 YP_001836314.1 CDS SPCG_1597 NC_010582.1 1563645 1566791 D snf2 family protein 1563645..1566791 Streptococcus pneumoniae CGSP14 6217102 YP_001836315.1 CDS ctpE NC_010582.1 1567228 1569564 R cation transporter E1-E2 family ATPase complement(1567228..1569564) Streptococcus pneumoniae CGSP14 6218434 YP_001836316.1 CDS SPCG_1599 NC_010582.1 1569652 1570446 D acyltransferase family protein 1569652..1570446 Streptococcus pneumoniae CGSP14 6218465 YP_001836317.1 CDS cadD NC_010582.1 1570738 1571352 R cadmium resistance transporter complement(1570738..1571352) Streptococcus pneumoniae CGSP14 6218415 YP_001836318.1 CDS rpsO NC_010582.1 1572168 1572437 R primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 complement(1572168..1572437) Streptococcus pneumoniae CGSP14 6216386 YP_001836319.1 CDS SPCG_1602 NC_010582.1 1572452 1572556 R hypothetical protein complement(1572452..1572556) Streptococcus pneumoniae CGSP14 6218404 YP_001836320.1 CDS SPCG_1603 NC_010582.1 1572578 1573207 R hypothetical protein complement(1572578..1573207) Streptococcus pneumoniae CGSP14 6216420 YP_001836321.1 CDS SPCG_1604 NC_010582.1 1573716 1573820 D hypothetical protein 1573716..1573820 Streptococcus pneumoniae CGSP14 6216437 YP_001836322.1 CDS SPCG_1605 NC_010582.1 1574011 1574400 D hypothetical protein 1574011..1574400 Streptococcus pneumoniae CGSP14 6217082 YP_001836323.1 CDS thrS NC_010582.1 1574419 1576401 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1574419..1576401 Streptococcus pneumoniae CGSP14 6218407 YP_001836324.1 CDS SPCG_1607 NC_010582.1 1576450 1577424 R sensor histidine kinase complement(1576450..1577424) Streptococcus pneumoniae CGSP14 6218496 YP_001836325.1 CDS SPCG_1608 NC_010582.1 1577417 1578184 R DNA-binding response regulator complement(1577417..1578184) Streptococcus pneumoniae CGSP14 6218190 YP_001836326.1 CDS SPCG_1609 NC_010582.1 1578250 1579323 D hypothetical protein 1578250..1579323 Streptococcus pneumoniae CGSP14 6218094 YP_001836327.1 CDS SPCG_1610 NC_010582.1 1579786 1580223 R rrf2 family protein complement(1579786..1580223) Streptococcus pneumoniae CGSP14 6218143 YP_001836328.1 CDS SPCG_1611 NC_010582.1 1580299 1581147 R hypothetical protein complement(1580299..1581147) Streptococcus pneumoniae CGSP14 6217866 YP_001836329.1 CDS SPCG_1612 NC_010582.1 1581253 1581903 D iron-dependent transcriptional regulator 1581253..1581903 Streptococcus pneumoniae CGSP14 6218126 YP_001836330.1 CDS SPCG_1613 NC_010582.1 1581975 1583231 R IS1167, transposase complement(1581975..1583231) Streptococcus pneumoniae CGSP14 6218116 YP_001836331.1 CDS SPCG_1614 NC_010582.1 1583502 1584149 D hypothetical protein 1583502..1584149 Streptococcus pneumoniae CGSP14 6217867 YP_001836332.1 CDS SPCG_1615 NC_010582.1 1584280 1584693 D hypothetical protein 1584280..1584693 Streptococcus pneumoniae CGSP14 6217892 YP_001836333.1 CDS SPCG_1616 NC_010582.1 1584712 1584897 D hypothetical protein 1584712..1584897 Streptococcus pneumoniae CGSP14 6218140 YP_001836334.1 CDS SPCG_1617 NC_010582.1 1585164 1585607 R hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine; D-tyrosyl-tRNA(Tyr) deacylase complement(1585164..1585607) Streptococcus pneumoniae CGSP14 6216448 YP_001836335.1 CDS relA NC_010582.1 1585637 1587859 R GTP pyrophosphokinase complement(1585637..1587859) Streptococcus pneumoniae CGSP14 6217296 YP_001836336.1 CDS SPCG_1619 NC_010582.1 1588767 1589447 D metallo-beta-lactamase superfamily protein 1588767..1589447 Streptococcus pneumoniae CGSP14 6216915 YP_001836337.1 CDS pepO NC_010582.1 1589570 1591522 R endopeptidase O complement(1589570..1591522) Streptococcus pneumoniae CGSP14 6216833 YP_001836338.1 CDS SPCG_1621 NC_010582.1 1591720 1592475 D manganese ABC transporter ATP-binding protein 1591720..1592475 Streptococcus pneumoniae CGSP14 6217085 YP_001836339.1 CDS SPCG_1622 NC_010582.1 1592472 1593320 D manganese ABC transporter permease 1592472..1593320 Streptococcus pneumoniae CGSP14 6216934 YP_001836340.1 CDS SPCG_1623 NC_010582.1 1593340 1594281 D manganese ABC transporter manganese-binding adhesion liprotein 1593340..1594281 Streptococcus pneumoniae CGSP14 6216878 YP_001836341.1 CDS tpx NC_010582.1 1594377 1594895 D antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein; thiol peroxidase 1594377..1594895 Streptococcus pneumoniae CGSP14 6217009 YP_001836342.1 CDS SPCG_1625 NC_010582.1 1594991 1597765 R hypothetical protein complement(1594991..1597765) Streptococcus pneumoniae CGSP14 6217749 YP_001836343.1 CDS SPCG_1626 NC_010582.1 1597701 1598411 R ABC transporter ATP-binding protein complement(1597701..1598411) Streptococcus pneumoniae CGSP14 6217928 YP_001836344.1 CDS SPCG_1627 NC_010582.1 1598652 1601063 R hypothetical protein complement(1598652..1601063) Streptococcus pneumoniae CGSP14 6216680 YP_001836345.1 CDS gpmA NC_010582.1 1601116 1601808 R 2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate; phosphoglyceromutase complement(1601116..1601808) Streptococcus pneumoniae CGSP14 6217497 YP_001836346.1 CDS SPCG_1629 NC_010582.1 1601859 1602149 R hypothetical protein complement(1601859..1602149) Streptococcus pneumoniae CGSP14 6217208 YP_001836347.1 CDS SPCG_1630 NC_010582.1 1602343 1602723 R integral membrane protein complement(1602343..1602723) Streptococcus pneumoniae CGSP14 6216799 YP_001836348.1 CDS ileS NC_010582.1 1603126 1605918 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme; isoleucyl-tRNA synthetase complement(1603126..1605918) Streptococcus pneumoniae CGSP14 6216800 YP_001836349.1 CDS SPCG_1632 NC_010582.1 1606171 1606287 R hypothetical protein complement(1606171..1606287) Streptococcus pneumoniae CGSP14 6218292 YP_001836350.1 CDS SPCG_1633 NC_010582.1 1606266 1607066 R cell division protein DivIVA complement(1606266..1607066) Streptococcus pneumoniae CGSP14 6218186 YP_001836351.1 CDS divIVA NC_010582.1 1607063 1607848 R ylmH protein complement(1607063..1607848) Streptococcus pneumoniae CGSP14 6217185 YP_001836352.1 CDS SPCG_1635 NC_010582.1 1607845 1608108 R ylmG protein complement(1607845..1608108) Streptococcus pneumoniae CGSP14 6217506 YP_001836353.1 CDS SPCG_1636 NC_010582.1 1608108 1608647 R ylmF protein complement(1608108..1608647) Streptococcus pneumoniae CGSP14 6218223 YP_001836354.1 CDS SPCG_1637 NC_010582.1 1608657 1609328 R ylmE protein complement(1608657..1609328) Streptococcus pneumoniae CGSP14 6217540 YP_001836355.1 CDS SPCG_1638 NC_010582.1 1609333 1610592 R GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ complement(1609333..1610592) Streptococcus pneumoniae CGSP14 6217225 YP_001836356.1 CDS ftsZ NC_010582.1 1610609 1611982 R cell division protein FtsA complement(1610609..1611982) Streptococcus pneumoniae CGSP14 6218435 YP_001836357.1 CDS ftsA NC_010582.1 1612201 1612905 R hypothetical protein complement(1612201..1612905) Streptococcus pneumoniae CGSP14 6218439 YP_001836358.1 CDS SPCG_1641 NC_010582.1 1612996 1613607 R mutT/nudix family protein complement(1612996..1613607) Streptococcus pneumoniae CGSP14 6217529 YP_001836359.1 CDS mutT NC_010582.1 1613594 1614967 R UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate--D-alanyl-D-alanine ligase complement(1613594..1614967) Streptococcus pneumoniae CGSP14 6217155 YP_001836360.1 CDS ddl NC_010582.1 1615051 1616094 R D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanyl-alanine synthetase A complement(1615051..1616094) Streptococcus pneumoniae CGSP14 6217625 YP_001836361.1 CDS recR NC_010582.1 1616270 1616866 R involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR complement(1616270..1616866) Streptococcus pneumoniae CGSP14 6217425 YP_001836362.1 CDS pbp2B NC_010582.1 1616877 1618934 R penicillin-binding protein 2B complement(1616877..1618934) Streptococcus pneumoniae CGSP14 6216620 YP_001836363.1 CDS SPCG_1646 NC_010582.1 1619128 1619979 D phosphosugar-binding transcriptional regulator 1619128..1619979 Streptococcus pneumoniae CGSP14 6216447 YP_001836364.1 CDS SPCG_1647 NC_010582.1 1619995 1620879 R ROK family protein complement(1619995..1620879) Streptococcus pneumoniae CGSP14 6217040 YP_001836365.1 CDS SPCG_1648 NC_010582.1 1620897 1621814 R N-acetylneuraminate lyase complement(1620897..1621814) Streptococcus pneumoniae CGSP14 6217880 YP_001836366.1 CDS SPCG_1649 NC_010582.1 1621983 1622627 R hypothetical protein complement(1621983..1622627) Streptococcus pneumoniae CGSP14 6216538 YP_001836367.1 CDS SPCG_1650 NC_010582.1 1622609 1622707 R hypothetical protein complement(1622609..1622707) Streptococcus pneumoniae CGSP14 6216749 YP_001836368.1 CDS SPCG_1651 NC_010582.1 1622904 1623248 R hypothetical protein complement(1622904..1623248) Streptococcus pneumoniae CGSP14 6218375 YP_001836369.1 CDS SPCG_1652 NC_010582.1 1623345 1623797 R hypothetical protein complement(1623345..1623797) Streptococcus pneumoniae CGSP14 6217650 YP_001836370.1 CDS SPCG_1653 NC_010582.1 1623821 1623973 R hypothetical protein complement(1623821..1623973) Streptococcus pneumoniae CGSP14 6217115 YP_001836371.1 CDS SPCG_1654 NC_010582.1 1624069 1624908 R sugar ABC transporter permease complement(1624069..1624908) Streptococcus pneumoniae CGSP14 6218169 YP_001836372.1 CDS SPCG_1655 NC_010582.1 1624924 1625820 R sugar ABC transporter permease complement(1624924..1625820) Streptococcus pneumoniae CGSP14 6217914 YP_001836373.1 CDS SPCG_1656 NC_010582.1 1626042 1627370 R sugar ABC transporter sugar-binding protein complement(1626042..1627370) Streptococcus pneumoniae CGSP14 6216997 YP_001836374.1 CDS SPCG_1657 NC_010582.1 1627495 1629027 R PTS system transporter subunit IIBC complement(1627495..1629027) Streptococcus pneumoniae CGSP14 6217959 YP_001836375.1 CDS nanE NC_010582.1 1629031 1629729 R Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate; N-acetylmannosamine-6-phosphate 2-epimerase complement(1629031..1629729) Streptococcus pneumoniae CGSP14 6217351 YP_001836376.1 CDS SPCG_1659 NC_010582.1 1629903 1631006 R Gfo/Idh/MocA family oxidoreductase complement(1629903..1631006) Streptococcus pneumoniae CGSP14 6216596 YP_001836377.1 CDS nanB NC_010582.1 1631018 1633111 R neuraminidase B complement(1631018..1633111) Streptococcus pneumoniae CGSP14 6217694 YP_001836378.1 CDS SPCG_1661 NC_010582.1 1633129 1633962 R ABC transporter permease complement(1633129..1633962) Streptococcus pneumoniae CGSP14 6216824 YP_001836379.1 CDS SPCG_1662 NC_010582.1 1633962 1634846 R ABC transporter permease complement(1633962..1634846) Streptococcus pneumoniae CGSP14 6216812 YP_001836380.1 CDS SPCG_1663 NC_010582.1 1634925 1636262 R ABC transporter substrate-binding protein complement(1634925..1636262) Streptococcus pneumoniae CGSP14 6217422 YP_001836381.1 CDS SPCG_1664 NC_010582.1 1636281 1636733 R hypothetical protein complement(1636281..1636733) Streptococcus pneumoniae CGSP14 6217812 YP_001836382.1 CDS nanA NC_010582.1 1637747 1640689 R sialidase A (neuraminidase A) complement(1637747..1640689) Streptococcus pneumoniae CGSP14 6217600 YP_001836383.1 CDS SPCG_1666 NC_010582.1 1640932 1641159 R hypothetical protein complement(1640932..1641159) Streptococcus pneumoniae CGSP14 6216599 YP_001836384.1 CDS SPCG_1667 NC_010582.1 1641433 1642095 R hypothetical protein complement(1641433..1642095) Streptococcus pneumoniae CGSP14 6217647 YP_001836385.1 CDS axe1 NC_010582.1 1642414 1643394 R acetyl xylan esterase complement(1642414..1643394) Streptococcus pneumoniae CGSP14 6217576 YP_001836386.1 CDS recG NC_010582.1 1643951 1645966 R catalyzes branch migration in Holliday junction intermediates; ATP-dependent DNA helicase RecG complement(1643951..1645966) Streptococcus pneumoniae CGSP14 6218073 YP_001836387.1 CDS alr NC_010582.1 1645985 1647109 R converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer; alanine racemase complement(1645985..1647109) Streptococcus pneumoniae CGSP14 6217624 YP_001836388.1 CDS acpS NC_010582.1 1647078 1647449 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(1647078..1647449) Streptococcus pneumoniae CGSP14 6217207 YP_001836389.1 CDS aroF NC_010582.1 1647485 1648516 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1647485..1648516) Streptococcus pneumoniae CGSP14 6218597 YP_001836390.1 CDS aroG NC_010582.1 1648518 1649549 R catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive; phospho-2-dehydro-3-deoxyheptonate aldolase complement(1648518..1649549) Streptococcus pneumoniae CGSP14 6217411 YP_001836391.1 CDS secA NC_010582.1 1649630 1652143 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA complement(1649630..1652143) Streptococcus pneumoniae CGSP14 6216823 YP_001836392.1 CDS SPCG_1675 NC_010582.1 1652289 1652576 R hypothetical protein complement(1652289..1652576) Streptococcus pneumoniae CGSP14 6216932 YP_001836393.1 CDS SPCG_1676 NC_010582.1 1652587 1653237 R ABC transporter ATP-binding protein complement(1652587..1653237) Streptococcus pneumoniae CGSP14 6217071 YP_001836394.1 CDS SPCG_1677 NC_010582.1 1653241 1653921 R hypothetical protein complement(1653241..1653921) Streptococcus pneumoniae CGSP14 6216731 YP_001836395.1 CDS SPCG_1678 NC_010582.1 1653875 1654705 R hypothetical protein complement(1653875..1654705) Streptococcus pneumoniae CGSP14 6217696 YP_001836396.1 CDS SPCG_1679 NC_010582.1 1654851 1655189 R hypothetical protein complement(1654851..1655189) Streptococcus pneumoniae CGSP14 6217623 YP_001836397.1 CDS SPCG_1680 NC_010582.1 1655327 1655674 R hypothetical protein complement(1655327..1655674) Streptococcus pneumoniae CGSP14 6218581 YP_001836398.1 CDS engA NC_010582.1 1655753 1657063 R EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA complement(1655753..1657063) Streptococcus pneumoniae CGSP14 6217334 YP_001836399.1 CDS SPCG_1682 NC_010582.1 1657077 1657790 R nitroreductase family protein complement(1657077..1657790) Streptococcus pneumoniae CGSP14 6218258 YP_001836400.1 CDS dnaI NC_010582.1 1657787 1658683 R Primosomal protein that may act to load helicase DnaC during DNA replication; primosomal protein DnaI complement(1657787..1658683) Streptococcus pneumoniae CGSP14 6217409 YP_001836401.1 CDS SPCG_1684 NC_010582.1 1658684 1659853 R hypothetical protein complement(1658684..1659853) Streptococcus pneumoniae CGSP14 6216522 YP_001836402.1 CDS nrdR NC_010582.1 1659854 1660387 R NrdR family transcriptional regulator complement(1659854..1660387) Streptococcus pneumoniae CGSP14 6216660 YP_001836403.1 CDS SPCG_1686 NC_010582.1 1660467 1660832 D GntR family transcriptional regulator 1660467..1660832 Streptococcus pneumoniae CGSP14 6217423 YP_001836404.1 CDS SPCG_1687 NC_010582.1 1660810 1661532 D ABC transporter ATP-binding protein 1660810..1661532 Streptococcus pneumoniae CGSP14 6218098 YP_001836405.1 CDS SPCG_1688 NC_010582.1 1661468 1662316 D ABC transporter ATP-binding protein 1661468..1662316 Streptococcus pneumoniae CGSP14 6218159 YP_001836406.1 CDS SPCG_1689 NC_010582.1 1662669 1663868 R hypothetical protein complement(1662669..1663868) Streptococcus pneumoniae CGSP14 6218080 YP_001836407.1 CDS SPCG_1690 NC_010582.1 1663865 1664758 R ABC transporter ATP-binding protein complement(1663865..1664758) Streptococcus pneumoniae CGSP14 6217055 YP_001836408.1 CDS SPCG_1691 NC_010582.1 1665149 1665250 R hypothetical protein complement(1665149..1665250) Streptococcus pneumoniae CGSP14 6218141 YP_001836409.1 CDS SPCG_1692 NC_010582.1 1666068 1666685 D hypothetical protein 1666068..1666685 Streptococcus pneumoniae CGSP14 6216865 YP_001836410.1 CDS scrK NC_010582.1 1666728 1667615 R fructokinase complement(1666728..1667615) Streptococcus pneumoniae CGSP14 6216426 YP_001836411.1 CDS scrA NC_010582.1 1667764 1669725 R PTS system IIABC components complement(1667764..1669725) Streptococcus pneumoniae CGSP14 6216894 YP_001836412.1 CDS SPCG_1695 NC_010582.1 1669827 1670024 R hypothetical protein complement(1669827..1670024) Streptococcus pneumoniae CGSP14 6217303 YP_001836413.1 CDS scrB NC_010582.1 1670077 1671531 D sucrose-6-phosphate hydrolase 1670077..1671531 Streptococcus pneumoniae CGSP14 6217545 YP_001836414.1 CDS scrR NC_010582.1 1671512 1672477 D sucrose operon repressor 1671512..1672477 Streptococcus pneumoniae CGSP14 6218284 YP_001836415.1 CDS mvaA NC_010582.1 1672512 1673786 R 3-hydroxy-3-methylglutaryl-CoA reductase complement(1672512..1673786) Streptococcus pneumoniae CGSP14 6218114 YP_001836416.1 CDS mvaS NC_010582.1 1673786 1674982 R hydroxymethylglutaryl-CoA synthase complement(1673786..1674982) Streptococcus pneumoniae CGSP14 6217717 YP_001836417.1 CDS SPCG_1700 NC_010582.1 1675089 1675376 R hypothetical protein complement(1675089..1675376) Streptococcus pneumoniae CGSP14 6218059 YP_001836418.1 CDS SPCG_1701 NC_010582.1 1675405 1675794 R IS1381 transposase protein B complement(1675405..1675794) Streptococcus pneumoniae CGSP14 6217396 YP_001836419.1 CDS SPCG_1702 NC_010582.1 1675828 1676028 R IS1381 transposase protein A, truncation complement(1675828..1676028) Streptococcus pneumoniae CGSP14 6217295 YP_001836420.1 CDS SPCG_1703 NC_010582.1 1676093 1676542 R hypothetical protein complement(1676093..1676542) Streptococcus pneumoniae CGSP14 6218286 YP_001836421.1 CDS SPCG_1704 NC_010582.1 1676544 1677302 R hypothetical protein complement(1676544..1677302) Streptococcus pneumoniae CGSP14 6218277 YP_001836422.1 CDS pkn2 NC_010582.1 1677417 1679396 R serine/threonine protein kinase complement(1677417..1679396) Streptococcus pneumoniae CGSP14 6216473 YP_001836423.1 CDS pppL NC_010582.1 1679393 1680133 R phosphatase complement(1679393..1680133) Streptococcus pneumoniae CGSP14 6217186 YP_001836424.1 CDS sunL NC_010582.1 1680148 1681464 R rRNA methyltransferase RsmB complement(1680148..1681464) Streptococcus pneumoniae CGSP14 6216843 YP_001836425.1 CDS fmt NC_010582.1 1681454 1682389 R modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth; methionyl-tRNA formyltransferase complement(1681454..1682389) Streptococcus pneumoniae CGSP14 6217758 YP_001836426.1 CDS SPCG_1709 NC_010582.1 1682402 1683376 R primosome assembly protein PriA complement(1682402..1683376) Streptococcus pneumoniae CGSP14 6218228 YP_001836427.1 CDS SPCG_1710 NC_010582.1 1683370 1684797 R primosome assembly protein PriA complement(1683370..1684797) Streptococcus pneumoniae CGSP14 6216421 YP_001836428.1 CDS SPCG_1711 NC_010582.1 1684863 1685177 R Promotes RNA polymerase assembly. Latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits; DNA-directed RNA polymerase subunit omega complement(1684863..1685177) Streptococcus pneumoniae CGSP14 6217878 YP_001836429.1 CDS gmk NC_010582.1 1685202 1685828 R Essential for recycling GMP and indirectly, cGMP; guanylate kinase complement(1685202..1685828) Streptococcus pneumoniae CGSP14 6217653 YP_001836430.1 CDS SPCG_1713 NC_010582.1 1685958 1687571 R hypothetical protein complement(1685958..1687571) Streptococcus pneumoniae CGSP14 6217557 YP_001836431.1 CDS SPCG_1714 NC_010582.1 1687762 1688016 R hypothetical protein complement(1687762..1688016) Streptococcus pneumoniae CGSP14 6218507 YP_001836432.1 CDS SPCG_1715 NC_010582.1 1688020 1688313 R hypothetical protein complement(1688020..1688313) Streptococcus pneumoniae CGSP14 6218417 YP_001836433.1 CDS SPCG_1716 NC_010582.1 1688512 1689609 R hypothetical protein complement(1688512..1689609) Streptococcus pneumoniae CGSP14 6218570 YP_001836434.1 CDS SPCG_1717 NC_010582.1 1689619 1690374 R hypothetical protein complement(1689619..1690374) Streptococcus pneumoniae CGSP14 6216641 YP_001836435.1 CDS SPCG_1718 NC_010582.1 1690679 1691032 R iojap-like protein complement(1690679..1691032) Streptococcus pneumoniae CGSP14 6216537 YP_001836436.1 CDS SPCG_1719 NC_010582.1 1691045 1691545 R isochorismatase family protein complement(1691045..1691545) Streptococcus pneumoniae CGSP14 6218104 YP_001836437.1 CDS SPCG_1720 NC_010582.1 1691546 1692139 R hypothetical protein complement(1691546..1692139) Streptococcus pneumoniae CGSP14 6218147 YP_001836438.1 CDS nadD NC_010582.1 1692139 1692768 R transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria; nicotinic acid mononucleotide adenylyltransferase complement(1692139..1692768) Streptococcus pneumoniae CGSP14 6217589 YP_001836439.1 CDS SPCG_1722 NC_010582.1 1692820 1693131 R hypothetical protein complement(1692820..1693131) Streptococcus pneumoniae CGSP14 6216718 YP_001836440.1 CDS SPCG_1723 NC_010582.1 1693331 1694437 R in Bacillus subtilis this enzyme appears to be involved in 30S ribosomal RNA subunit biogenesis; GTP-binding protein YqeH complement(1693331..1694437) Streptococcus pneumoniae CGSP14 6216403 YP_001836441.1 CDS SPCG_1724 NC_010582.1 1694440 1695030 R hypothetical protein complement(1694440..1695030) Streptococcus pneumoniae CGSP14 6217154 YP_001836442.1 CDS corA NC_010582.1 1694982 1695890 R CorA family protein complement(1694982..1695890) Streptococcus pneumoniae CGSP14 6217050 YP_001836443.1 CDS SPCG_1726 NC_010582.1 1695947 1696552 R mechanosensitive ion channel complement(1695947..1696552) Streptococcus pneumoniae CGSP14 6218544 YP_001836444.1 CDS dctA NC_010582.1 1696896 1697855 D involved in the import of serine and threonine coupled with the import of sodium; serine/threonine transporter SstT 1696896..1697855 Streptococcus pneumoniae CGSP14 6218356 YP_001836445.1 CDS SPCG_1728 NC_010582.1 1697923 1698876 D hypothetical protein 1697923..1698876 Streptococcus pneumoniae CGSP14 6218595 YP_001836446.1 CDS SPCG_1729 NC_010582.1 1698893 1699132 R hypothetical protein complement(1698893..1699132) Streptococcus pneumoniae CGSP14 6216786 YP_001836447.1 CDS SPCG_1730 NC_010582.1 1699243 1700535 D IS1167, transposase 1699243..1700535 Streptococcus pneumoniae CGSP14 6217551 YP_001836448.1 CDS SPCG_1731 NC_010582.1 1700578 1700802 R hypothetical protein complement(1700578..1700802) Streptococcus pneumoniae CGSP14 6217256 YP_001836449.1 CDS SPCG_1732 NC_010582.1 1700807 1700986 R hypothetical protein complement(1700807..1700986) Streptococcus pneumoniae CGSP14 6217188 YP_001836450.1 CDS SPCG_1733 NC_010582.1 1700988 1702325 R hypothetical protein complement(1700988..1702325) Streptococcus pneumoniae CGSP14 6217170 YP_001836451.1 CDS SPCG_1734 NC_010582.1 1702318 1703829 R group 1 glycosyl transferase complement(1702318..1703829) Streptococcus pneumoniae CGSP14 6217676 YP_001836452.1 CDS SPCG_1735 NC_010582.1 1703841 1706213 R functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; in some organisms, especially gram positive pathogens, have paralogs that have been found to be nonessential but do function in secretion of a subset of exported proteins; preprotein translocase subunit SecA complement(1703841..1706213) Streptococcus pneumoniae CGSP14 6216631 YP_001836453.1 CDS SPCG_1736 NC_010582.1 1706206 1706646 R hypothetical protein complement(1706206..1706646) Streptococcus pneumoniae CGSP14 6216886 YP_001836454.1 CDS SPCG_1737 NC_010582.1 1706643 1708178 R hypothetical protein complement(1706643..1708178) Streptococcus pneumoniae CGSP14 6217455 YP_001836455.1 CDS SPCG_1738 NC_010582.1 1708162 1709742 R hypothetical protein complement(1708162..1709742) Streptococcus pneumoniae CGSP14 6218532 YP_001836456.1 CDS secY NC_010582.1 1709752 1710969 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(1709752..1710969) Streptococcus pneumoniae CGSP14 6217214 YP_001836457.1 CDS SPCG_1740 NC_010582.1 1711026 1711703 R glycosyl transferase family protein complement(1711026..1711703) Streptococcus pneumoniae CGSP14 6216888 YP_001836458.1 CDS SPCG_1741 NC_010582.1 1711930 1713126 R glycosyl transferase family protein complement(1711930..1713126) Streptococcus pneumoniae CGSP14 6216482 YP_001836459.1 CDS SPCG_1742 NC_010582.1 1713135 1714355 R glycosyl transferase family protein complement(1713135..1714355) Streptococcus pneumoniae CGSP14 6216658 YP_001836460.1 CDS SPCG_1743 NC_010582.1 1714386 1716830 R glycosyl transferase family protein complement(1714386..1716830) Streptococcus pneumoniae CGSP14 6217836 YP_001836461.1 CDS SPCG_1744 NC_010582.1 1716840 1717850 R hypothetical protein complement(1716840..1717850) Streptococcus pneumoniae CGSP14 6218167 YP_001836462.1 CDS SPCG_1745 NC_010582.1 1717890 1719095 R glycosyl transferase family protein complement(1717890..1719095) Streptococcus pneumoniae CGSP14 6216728 YP_001836463.1 CDS SPCG_1746 NC_010582.1 1719104 1719979 R glycosyl transferase family protein complement(1719104..1719979) Streptococcus pneumoniae CGSP14 6216556 YP_001836464.1 CDS SPCG_1747 NC_010582.1 1720434 1721192 R hypothetical protein complement(1720434..1721192) Streptococcus pneumoniae CGSP14 6217469 YP_001836465.1 CDS SPCG_1748 NC_010582.1 1721202 1722080 R exopolysaccharide biosynthesis acetyltransferase complement(1721202..1722080) Streptococcus pneumoniae CGSP14 6217161 YP_001836466.1 CDS SPCG_1749 NC_010582.1 1722077 1724167 R glycosyl transferase family protein complement(1722077..1724167) Streptococcus pneumoniae CGSP14 6217748 YP_001836467.1 CDS SPCG_1750 NC_010582.1 1724222 1738309 R cell wall surface anchor family protein complement(1724222..1738309) Streptococcus pneumoniae CGSP14 6217791 YP_001836468.1 CDS SPCG_1751 NC_010582.1 1738670 1739131 R degenerate transposase complement(1738670..1739131) Streptococcus pneumoniae CGSP14 6217921 YP_001836469.1 CDS SPCG_1752 NC_010582.1 1739464 1739889 D transcriptional regulator 1739464..1739889 Streptococcus pneumoniae CGSP14 6217160 YP_001836470.1 CDS SPCG_1753 NC_010582.1 1739907 1740209 D hypothetical protein 1739907..1740209 Streptococcus pneumoniae CGSP14 6216673 YP_001836471.1 CDS trxA NC_010582.1 1740226 1740540 D thioredoxin 1740226..1740540 Streptococcus pneumoniae CGSP14 6218085 YP_001836472.1 CDS SPCG_1755 NC_010582.1 1740807 1741379 D NADPH-dependent; catalyzes the reduction of 7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in queuosine biosynthesis; 7-cyano-7-deazaguanine reductase 1740807..1741379 Streptococcus pneumoniae CGSP14 6217530 YP_001836473.1 CDS aqpZ NC_010582.1 1741634 1742302 R aquaporin complement(1741634..1742302) Streptococcus pneumoniae CGSP14 6217259 YP_001836474.1 CDS SPCG_1757 NC_010582.1 1742413 1743210 R hypothetical protein complement(1742413..1743210) Streptococcus pneumoniae CGSP14 6216910 YP_001836475.1 CDS pepF NC_010582.1 1743450 1745246 R oligoendopeptidase F complement(1743450..1745246) Streptococcus pneumoniae CGSP14 6216381 YP_001836476.1 CDS SPCG_1759 NC_010582.1 1745257 1746012 R in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE complement(1745257..1746012) Streptococcus pneumoniae CGSP14 6217862 YP_001836477.1 CDS prmA NC_010582.1 1746002 1746952 R methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype; 50S ribosomal protein L11 methyltransferase complement(1746002..1746952) Streptococcus pneumoniae CGSP14 6217377 YP_001836478.1 CDS SPCG_1761 NC_010582.1 1746965 1747984 R hypothetical protein complement(1746965..1747984) Streptococcus pneumoniae CGSP14 6217740 YP_001836479.1 CDS SPCG_1762 NC_010582.1 1748035 1750278 R subtilisin-like serine protease complement(1748035..1750278) Streptococcus pneumoniae CGSP14 6217615 YP_001836480.1 CDS SPCG_1763 NC_010582.1 1750280 1751314 R ATPase AAA complement(1750280..1751314) Streptococcus pneumoniae CGSP14 6217754 YP_001836481.1 CDS SPCG_1764 NC_010582.1 1751424 1751582 R mutT/nudix family protein complement(1751424..1751582) Streptococcus pneumoniae CGSP14 6218583 YP_001836482.1 CDS SPCG_1765 NC_010582.1 1751563 1752666 R hypothetical protein complement(1751563..1752666) Streptococcus pneumoniae CGSP14 6218319 YP_001836483.1 CDS SPCG_1766 NC_010582.1 1752670 1753140 R hypothetical protein complement(1752670..1753140) Streptococcus pneumoniae CGSP14 6217831 YP_001836484.1 CDS SPCG_1767 NC_010582.1 1753431 1753883 R hypothetical protein complement(1753431..1753883) Streptococcus pneumoniae CGSP14 6217535 YP_001836485.1 CDS SPCG_1768 NC_010582.1 1754236 1754415 R hypothetical protein complement(1754236..1754415) Streptococcus pneumoniae CGSP14 6218588 YP_001836486.1 CDS SPCG_1769 NC_010582.1 1754486 1754590 R hypothetical protein complement(1754486..1754590) Streptococcus pneumoniae CGSP14 6218337 YP_001836487.1 CDS SPCG_1770 NC_010582.1 1754580 1754822 R hypothetical protein complement(1754580..1754822) Streptococcus pneumoniae CGSP14 6216374 YP_001836488.1 CDS SPCG_1771 NC_010582.1 1755092 1756363 D recombination factor protein RarA 1755092..1756363 Streptococcus pneumoniae CGSP14 6217047 YP_001836489.1 CDS sacA NC_010582.1 1756908 1758233 R sucrose-6-phosphate hydrolase complement(1756908..1758233) Streptococcus pneumoniae CGSP14 6217373 YP_001836490.1 CDS SPCG_1773 NC_010582.1 1758237 1759949 R ABC transporter substrate-binding protein complement(1758237..1759949) Streptococcus pneumoniae CGSP14 6216616 YP_001836491.1 CDS SPCG_1774 NC_010582.1 1759882 1760799 R ABC transporter permease complement(1759882..1760799) Streptococcus pneumoniae CGSP14 6218005 YP_001836492.1 CDS SPCG_1775 NC_010582.1 1760783 1761727 R ABC transporter permease complement(1760783..1761727) Streptococcus pneumoniae CGSP14 6217995 YP_001836493.1 CDS SPCG_1776 NC_010582.1 1761850 1762869 R LacI family sugar-binding transcriptional regulator complement(1761850..1762869) Streptococcus pneumoniae CGSP14 6217117 YP_001836494.1 CDS SPCG_1777 NC_010582.1 1763212 1764750 R transcriptional activator complement(1763212..1764750) Streptococcus pneumoniae CGSP14 6218160 YP_001836495.1 CDS SPCG_1778 NC_010582.1 1765136 1765300 D hypothetical protein 1765136..1765300 Streptococcus pneumoniae CGSP14 6217720 YP_001836496.1 CDS SPCG_1779 NC_010582.1 1765378 1765950 D hypothetical protein 1765378..1765950 Streptococcus pneumoniae CGSP14 6217101 YP_001836497.1 CDS SPCG_1780 NC_010582.1 1765962 1766132 D hypothetical protein 1765962..1766132 Streptococcus pneumoniae CGSP14 6216679 YP_001836498.1 CDS SPCG_1781 NC_010582.1 1766171 1766779 D general stress protein 24 1766171..1766779 Streptococcus pneumoniae CGSP14 6218569 YP_001836499.1 CDS SPCG_1782 NC_010582.1 1766810 1767013 D hypothetical protein 1766810..1767013 Streptococcus pneumoniae CGSP14 6218575 YP_001836500.1 CDS SPCG_1783 NC_010582.1 1768163 1768933 R hypothetical protein complement(1768163..1768933) Streptococcus pneumoniae CGSP14 6218566 YP_001836501.1 CDS SPCG_1784 NC_010582.1 1768948 1769796 R hypothetical protein complement(1768948..1769796) Streptococcus pneumoniae CGSP14 6216413 YP_001836502.1 CDS SPCG_1785 NC_010582.1 1769793 1771268 R can hydrolyze p-nitrophenyl sulfate; contains a specific cysteine that is converted into C{alpha]-formylglycine upon activation with the anaerobic sulfatase-maturase; arylsulfatase complement(1769793..1771268) Streptococcus pneumoniae CGSP14 6218535 YP_001836503.1 CDS SPCG_1786 NC_010582.1 1771591 1772946 R PTS system cellobiose-specific transporter subunit IIC complement(1771591..1772946) Streptococcus pneumoniae CGSP14 6216399 YP_001836504.1 CDS SPCG_1787 NC_010582.1 1772956 1773273 R PTS system cellobiose-specific transporter subunit IIA complement(1772956..1773273) Streptococcus pneumoniae CGSP14 6218541 YP_001836505.1 CDS SPCG_1788 NC_010582.1 1773290 1773607 R PTS system transporter subunit IIB complement(1773290..1773607) Streptococcus pneumoniae CGSP14 6218491 YP_001836506.1 CDS SPCG_1789 NC_010582.1 1773622 1774524 R PEP phosphonomutase-like protein complement(1773622..1774524) Streptococcus pneumoniae CGSP14 6218486 YP_001836507.1 CDS SPCG_1790 NC_010582.1 1774521 1775783 R phosphotransferase system cellobiose-specific component IIC complement(1774521..1775783) Streptococcus pneumoniae CGSP14 6217785 YP_001836508.1 CDS SPCG_1791 NC_010582.1 1776063 1777241 D ROK family protein 1776063..1777241 Streptococcus pneumoniae CGSP14 6217421 YP_001836509.1 CDS SPCG_1792 NC_010582.1 1777469 1777915 R acetyltransferase complement(1777469..1777915) Streptococcus pneumoniae CGSP14 6217417 YP_001836510.1 CDS SPCG_1793 NC_010582.1 1777931 1778065 R hypothetical protein complement(1777931..1778065) Streptococcus pneumoniae CGSP14 6218567 YP_001836511.1 CDS pilD NC_010582.1 1778039 1778644 D type IV prepilin peptidase 1778039..1778644 Streptococcus pneumoniae CGSP14 6218367 YP_001836512.1 CDS trpA NC_010582.1 1778616 1779461 R catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis; tryptophan synthase subunit alpha complement(1778616..1779461) Streptococcus pneumoniae CGSP14 6217385 YP_001836513.1 CDS trpB NC_010582.1 1779385 1780608 R catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; tryptophan synthase subunit beta complement(1779385..1780608) Streptococcus pneumoniae CGSP14 6217257 YP_001836514.1 CDS trpF NC_010582.1 1780586 1781215 R catalyzes the formation of 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate from N-(5-phospho-beta-D-ribosyl)-anthranilate in tryptophan biosynthesis; N-(5'-phosphoribosyl)anthranilate isomerase complement(1780586..1781215) Streptococcus pneumoniae CGSP14 6217958 YP_001836515.1 CDS trpC NC_010582.1 1781172 1781939 R involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; indole-3-glycerol-phosphate synthase complement(1781172..1781939) Streptococcus pneumoniae CGSP14 6218293 YP_001836516.1 CDS trpD NC_010582.1 1781936 1782940 R Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate; anthranilate phosphoribosyltransferase complement(1781936..1782940) Streptococcus pneumoniae CGSP14 6218383 YP_001836517.1 CDS trpG NC_010582.1 1782951 1783517 R TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; anthranilate synthase component II complement(1782951..1783517) Streptococcus pneumoniae CGSP14 6218298 YP_001836518.1 CDS trpE NC_010582.1 1783514 1784977 R with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine; anthranilate synthase component I complement(1783514..1784977) Streptococcus pneumoniae CGSP14 6217673 YP_001836519.1 CDS SPCG_1802 NC_010582.1 1785169 1785261 R hypothetical protein complement(1785169..1785261) Streptococcus pneumoniae CGSP14 6217126 YP_001836520.1 CDS SPCG_1803 NC_010582.1 1785248 1785499 R hypothetical protein complement(1785248..1785499) Streptococcus pneumoniae CGSP14 6216722 YP_001836521.1 CDS SPCG_1804 NC_010582.1 1786107 1787108 R LacI family sugar-binding transcriptional regulator complement(1786107..1787108) Streptococcus pneumoniae CGSP14 6218470 YP_001836522.1 CDS SPCG_1805 NC_010582.1 1787679 1788389 R mgtC/SapB family protein complement(1787679..1788389) Streptococcus pneumoniae CGSP14 6218398 YP_001836523.1 CDS SPCG_1806 NC_010582.1 1788392 1789903 R ABC transporter permease complement(1788392..1789903) Streptococcus pneumoniae CGSP14 6216431 YP_001836524.1 CDS SPCG_1807 NC_010582.1 1790094 1791104 R ABC transporter ATP-binding protein complement(1790094..1791104) Streptococcus pneumoniae CGSP14 6218530 YP_001836525.1 CDS SPCG_1808 NC_010582.1 1791207 1792274 R ABC transporter substrate-binding protein complement(1791207..1792274) Streptococcus pneumoniae CGSP14 6218410 YP_001836526.1 CDS SPCG_1809 NC_010582.1 1792299 1792958 R hypothetical protein complement(1792299..1792958) Streptococcus pneumoniae CGSP14 6216412 YP_001836527.1 CDS SPCG_1810 NC_010582.1 1793687 1793983 R hypothetical protein complement(1793687..1793983) Streptococcus pneumoniae CGSP14 6217815 YP_001836528.1 CDS SPCG_1811 NC_010582.1 1793967 1796126 R cell wall surface anchor family protein complement(1793967..1796126) Streptococcus pneumoniae CGSP14 6217338 YP_001836529.1 CDS SPCG_1812 NC_010582.1 1797256 1798509 R capsular polysaccharide biosynthesis protein complement(1797256..1798509) Streptococcus pneumoniae CGSP14 6217285 YP_001836530.1 CDS SPCG_1813 NC_010582.1 1798525 1799256 R glycosyl transferase family protein complement(1798525..1799256) Streptococcus pneumoniae CGSP14 6218024 YP_001836531.1 CDS SPCG_1814 NC_010582.1 1799390 1801141 R ABC transporter ATP-binding protein/permease complement(1799390..1801141) Streptococcus pneumoniae CGSP14 6217290 YP_001836532.1 CDS SPCG_1815 NC_010582.1 1801131 1802915 R ABC transporter ATP-binding protein/permease complement(1801131..1802915) Streptococcus pneumoniae CGSP14 6217802 YP_001836533.1 CDS SPCG_1816 NC_010582.1 1803004 1803534 R hypothetical protein complement(1803004..1803534) Streptococcus pneumoniae CGSP14 6218480 YP_001836534.1 CDS SPCG_1817 NC_010582.1 1803531 1803800 R hypothetical protein complement(1803531..1803800) Streptococcus pneumoniae CGSP14 6217370 YP_001836535.1 CDS exoA NC_010582.1 1804120 1804947 D exodeoxyribonuclease 1804120..1804947 Streptococcus pneumoniae CGSP14 6216939 YP_001836536.1 CDS SPCG_1819 NC_010582.1 1805102 1805206 D hypothetical protein 1805102..1805206 Streptococcus pneumoniae CGSP14 6217882 YP_001836537.1 CDS SPCG_1820 NC_010582.1 1805210 1805341 D hypothetical protein 1805210..1805341 Streptococcus pneumoniae CGSP14 6216683 YP_001836538.1 CDS xpt NC_010582.1 1806219 1806800 D Catalyzes the transfer of the phosphoribosyl moiety from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the 6-oxo-guanine and -xanthine; xanthine phosphoribosyltransferase 1806219..1806800 Streptococcus pneumoniae CGSP14 6218023 YP_001836539.1 CDS SPCG_1822 NC_010582.1 1806800 1808062 D xanthine permease 1806800..1808062 Streptococcus pneumoniae CGSP14 6216594 YP_001836540.1 CDS dpnD NC_010582.1 1808113 1808574 R dpnD protein complement(1808113..1808574) Streptococcus pneumoniae CGSP14 6217320 YP_001836541.1 CDS dpnC NC_010582.1 1808571 1809335 R type II restriction endonuclease DpnI complement(1808571..1809335) Streptococcus pneumoniae CGSP14 6218551 YP_001836542.1 CDS SPCG_1825 NC_010582.1 1809577 1809957 R hypothetical protein complement(1809577..1809957) Streptococcus pneumoniae CGSP14 6217404 YP_001836543.1 CDS galT NC_010582.1 1810006 1811487 R catalyzes the formation of alpha-D-glucose 1-phosphate and UDP-galactose from UDP-glucose and alpha-D-galactose 1-phosphate in galactose metabolism; galactose-1-phosphate uridylyltransferase complement(1810006..1811487) Streptococcus pneumoniae CGSP14 6217075 YP_001836544.1 CDS galK NC_010582.1 1811506 1812684 R catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism; galactokinase complement(1811506..1812684) Streptococcus pneumoniae CGSP14 6217626 YP_001836545.1 CDS galR NC_010582.1 1812848 1813855 D galactose operon repressor 1812848..1813855 Streptococcus pneumoniae CGSP14 6216615 YP_001836546.1 CDS adhB NC_010582.1 1813901 1814938 R zinc-containing alcohol dehydrogenase complement(1813901..1814938) Streptococcus pneumoniae CGSP14 6217474 YP_001836547.1 CDS SPCG_1830 NC_010582.1 1814939 1815292 R MerR family transcriptional regulator complement(1814939..1815292) Streptococcus pneumoniae CGSP14 6216825 YP_001836548.1 CDS SPCG_1831 NC_010582.1 1815536 1816435 R cation efflux system protein complement(1815536..1816435) Streptococcus pneumoniae CGSP14 6217446 YP_001836549.1 CDS SPCG_1832 NC_010582.1 1816559 1817095 D TetR family transcriptional regulator 1816559..1817095 Streptococcus pneumoniae CGSP14 6218543 YP_001836550.1 CDS SPCG_1833 NC_010582.1 1817261 1818070 R transporter complement(1817261..1818070) Streptococcus pneumoniae CGSP14 6217869 YP_001836551.1 CDS SPCG_1834 NC_010582.1 1818411 1819946 R choline transporter complement(1818411..1819946) Streptococcus pneumoniae CGSP14 6217138 YP_001836552.1 CDS SPCG_1835 NC_010582.1 1819924 1820652 R choline transporter complement(1819924..1820652) Streptococcus pneumoniae CGSP14 6218328 YP_001836553.1 CDS SPCG_1836 NC_010582.1 1820667 1821431 R hypothetical protein complement(1820667..1821431) Streptococcus pneumoniae CGSP14 6217877 YP_001836554.1 CDS SPCG_1837 NC_010582.1 1821435 1821878 R MarR family transcriptional regulator complement(1821435..1821878) Streptococcus pneumoniae CGSP14 6218125 YP_001836555.1 CDS SPCG_1838 NC_010582.1 1822560 1822865 R hypothetical protein complement(1822560..1822865) Streptococcus pneumoniae CGSP14 6217735 YP_001836556.1 CDS pepA NC_010582.1 1822878 1823942 R glutamyl-aminopeptidase complement(1822878..1823942) Streptococcus pneumoniae CGSP14 6217871 YP_001836557.1 CDS SPCG_1840 NC_010582.1 1824343 1825044 D NAD-dependent epimerase/dehydratase family protein 1824343..1825044 Streptococcus pneumoniae CGSP14 6216972 YP_001836558.1 CDS SPCG_1841 NC_010582.1 1825060 1825170 D hypothetical protein 1825060..1825170 Streptococcus pneumoniae CGSP14 6217201 YP_001836559.1 CDS SPCG_1842 NC_010582.1 1825452 1826426 D iron-compound ABC transporter permease 1825452..1826426 Streptococcus pneumoniae CGSP14 6216493 YP_001836560.1 CDS SPCG_1843 NC_010582.1 1826416 1827372 D iron-compound ABC transporter permease 1826416..1827372 Streptococcus pneumoniae CGSP14 6216495 YP_001836561.1 CDS SPCG_1844 NC_010582.1 1827369 1828121 D iron-compound ABC transporter ATP-binding protein 1827369..1828121 Streptococcus pneumoniae CGSP14 6216896 YP_001836562.1 CDS SPCG_1845 NC_010582.1 1828217 1829182 D iron-compound ABC transporter iron-compound-binding protein 1828217..1829182 Streptococcus pneumoniae CGSP14 6217012 YP_001836563.1 CDS SPCG_1846 NC_010582.1 1829407 1829649 R hypothetical protein complement(1829407..1829649) Streptococcus pneumoniae CGSP14 6217692 YP_001836564.1 CDS rluB NC_010582.1 1829649 1830371 R ribosomal large subunit pseudouridine synthase B complement(1829649..1830371) Streptococcus pneumoniae CGSP14 6216481 YP_001836565.1 CDS scpB NC_010582.1 1830358 1830927 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpA; forms a homodimer; segregation and condensation protein B complement(1830358..1830927) Streptococcus pneumoniae CGSP14 6216628 YP_001836566.1 CDS scpA NC_010582.1 1830946 1831674 R functions during chromosome segregation; may form a condensin-like structure with SMC and ScpB; segregation and condensation protein A complement(1830946..1831674) Streptococcus pneumoniae CGSP14 6217341 YP_001836567.1 CDS xerD NC_010582.1 1831674 1832414 R site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; site-specific tyrosine recombinase XerD complement(1831674..1832414) Streptococcus pneumoniae CGSP14 6217094 YP_001836568.1 CDS SPCG_1851 NC_010582.1 1832405 1832866 R hypothetical protein complement(1832405..1832866) Streptococcus pneumoniae CGSP14 6217211 YP_001836569.1 CDS SPCG_1852 NC_010582.1 1832863 1833384 R hypothetical protein complement(1832863..1833384) Streptococcus pneumoniae CGSP14 6217424 YP_001836570.1 CDS SPCG_1853 NC_010582.1 1833360 1834370 R HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine; deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein complement(1833360..1834370) Streptococcus pneumoniae CGSP14 6216923 YP_001836571.1 CDS murI NC_010582.1 1834328 1835122 R converts L-glutamate to D-glutamate, a component of peptidoglycan; glutamate racemase complement(1834328..1835122) Streptococcus pneumoniae CGSP14 6217330 YP_001836572.1 CDS SPCG_1855 NC_010582.1 1835329 1835631 R hypothetical protein complement(1835329..1835631) Streptococcus pneumoniae CGSP14 6217771 YP_001836573.1 CDS dexS NC_010582.1 1835833 1837458 R dextran glucosidase DexS complement(1835833..1837458) Streptococcus pneumoniae CGSP14 6216967 YP_001836574.1 CDS treP NC_010582.1 1837636 1839753 R trehalose PTS system, IIABC components complement(1837636..1839753) Streptococcus pneumoniae CGSP14 6217099 YP_001836575.1 CDS treR NC_010582.1 1839788 1840498 D trehalose operon transcriptional repressor 1839788..1840498 Streptococcus pneumoniae CGSP14 6218406 YP_001836576.1 CDS SPCG_1859 NC_010582.1 1840653 1841171 D degenerate transposase 1840653..1841171 Streptococcus pneumoniae CGSP14 6217166 YP_001836577.1 CDS SPCG_1860 NC_010582.1 1841452 1841979 D degenerate transposase 1841452..1841979 Streptococcus pneumoniae CGSP14 6218283 YP_001836578.1 CDS amiF NC_010582.1 1842054 1843049 R oligopeptide ABC transporter ATP-binding protein AmiF complement(1842054..1843049) Streptococcus pneumoniae CGSP14 6216387 YP_001836579.1 CDS amiE NC_010582.1 1842991 1844058 R oligopeptide ABC transporter ATP-binding protein AmiE complement(1842991..1844058) Streptococcus pneumoniae CGSP14 6216416 YP_001836580.1 CDS amiD NC_010582.1 1844067 1844993 R oligopeptide ABC transporter permease AmiD complement(1844067..1844993) Streptococcus pneumoniae CGSP14 6216948 YP_001836581.1 CDS amiC NC_010582.1 1844993 1846489 R oligopeptide ABC transporter permease AmiC complement(1844993..1846489) Streptococcus pneumoniae CGSP14 6217816 YP_001836582.1 CDS amiA NC_010582.1 1846556 1848535 R oligopeptide ABC transporter oligopeptide-binding protein AmiA complement(1846556..1848535) Streptococcus pneumoniae CGSP14 6217593 YP_001836583.1 CDS SPCG_1866 NC_010582.1 1849221 1850414 R hypothetical protein complement(1849221..1850414) Streptococcus pneumoniae CGSP14 6216595 YP_001836584.1 CDS SPCG_1867 NC_010582.1 1850552 1852024 R sucrose phosphorylase complement(1850552..1852024) Streptococcus pneumoniae CGSP14 6218512 YP_001836585.1 CDS SPCG_1868 NC_010582.1 1852205 1852345 R hypothetical protein complement(1852205..1852345) Streptococcus pneumoniae CGSP14 6217795 YP_001836586.1 CDS SPCG_1869 NC_010582.1 1852352 1853209 R sugar ABC transporter permease complement(1852352..1853209) Streptococcus pneumoniae CGSP14 6218468 YP_001836587.1 CDS SPCG_1870 NC_010582.1 1853199 1854089 R sugar ABC transporter permease complement(1853199..1854089) Streptococcus pneumoniae CGSP14 6218501 YP_001836588.1 CDS SPCG_1871 NC_010582.1 1854079 1855338 R sugar ABC transporter sugar-binding protein complement(1854079..1855338) Streptococcus pneumoniae CGSP14 6218534 YP_001836589.1 CDS aga NC_010582.1 1855373 1857535 R alpha-galactosidase complement(1855373..1857535) Streptococcus pneumoniae CGSP14 6218387 YP_001836590.1 CDS msmR NC_010582.1 1857643 1858503 D msm operon regulatory protein 1857643..1858503 Streptococcus pneumoniae CGSP14 6218165 YP_001836591.1 CDS birA NC_010582.1 1858500 1859435 D catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon; biotin--protein ligase 1858500..1859435 Streptococcus pneumoniae CGSP14 6217950 YP_001836592.1 CDS SPCG_1875 NC_010582.1 1866338 1867693 R RNA methyltransferase complement(1866338..1867693) Streptococcus pneumoniae CGSP14 6217730 YP_001836593.1 CDS SPCG_1876 NC_010582.1 1867663 1868526 D aminoglycoside phosphotransferase 1867663..1868526 Streptococcus pneumoniae CGSP14 6218371 YP_001836594.1 CDS recX NC_010582.1 1868536 1869312 D binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities; recombination regulator RecX 1868536..1869312 Streptococcus pneumoniae CGSP14 6217857 YP_001836595.1 CDS SPCG_1878 NC_010582.1 1869401 1869934 D hypothetical protein 1869401..1869934 Streptococcus pneumoniae CGSP14 6216563 YP_001836596.1 CDS SPCG_1879 NC_010582.1 1870291 1870497 R hypothetical protein complement(1870291..1870497) Streptococcus pneumoniae CGSP14 6217641 YP_001836597.1 CDS SPCG_1880 NC_010582.1 1870657 1871886 D IS1167, transposase 1870657..1871886 Streptococcus pneumoniae CGSP14 6217059 YP_001836598.1 CDS groEL NC_010582.1 1871986 1873608 R 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL complement(1871986..1873608) Streptococcus pneumoniae CGSP14 6217433 YP_001836599.1 CDS groES NC_010582.1 1873624 1873908 R 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES complement(1873624..1873908) Streptococcus pneumoniae CGSP14 6217284 YP_001836600.1 CDS ssbB NC_010582.1 1874178 1874573 R binds to single stranded DNA and may facilitate the binding and interaction of other proteins to DNA; single-stranded DNA-binding protein complement(1874178..1874573) Streptococcus pneumoniae CGSP14 6216947 YP_001836601.1 CDS ydfG NC_010582.1 1874650 1875411 R short chain dehydrogenase/reductase family oxidoreductase complement(1874650..1875411) Streptococcus pneumoniae CGSP14 6217093 YP_001836602.1 CDS SPCG_1885 NC_010582.1 1875444 1876070 R hypothetical protein complement(1875444..1876070) Streptococcus pneumoniae CGSP14 6216743 YP_001836603.1 CDS SPCG_1886 NC_010582.1 1876086 1876403 R thioredoxin complement(1876086..1876403) Streptococcus pneumoniae CGSP14 6216492 YP_001836604.1 CDS SPCG_1887 NC_010582.1 1876400 1876699 R hypothetical protein complement(1876400..1876699) Streptococcus pneumoniae CGSP14 6217788 YP_001836605.1 CDS SPCG_1888 NC_010582.1 1877036 1877251 R hypothetical protein complement(1877036..1877251) Streptococcus pneumoniae CGSP14 6216694 YP_001836606.1 CDS SPCG_1889 NC_010582.1 1877388 1878062 R hypothetical protein complement(1877388..1878062) Streptococcus pneumoniae CGSP14 6217566 YP_001836607.1 CDS SPCG_1890 NC_010582.1 1878068 1878517 R hypothetical protein complement(1878068..1878517) Streptococcus pneumoniae CGSP14 6217722 YP_001836608.1 CDS SPCG_1891 NC_010582.1 1878628 1879131 R PAP2 family protein complement(1878628..1879131) Streptococcus pneumoniae CGSP14 6216390 YP_001836609.1 CDS SPCG_1892 NC_010582.1 1879128 1879490 R hypothetical protein complement(1879128..1879490) Streptococcus pneumoniae CGSP14 6217790 YP_001836610.1 CDS SPCG_1893 NC_010582.1 1879556 1880587 R ABC transporter ATP-binding protein complement(1879556..1880587) Streptococcus pneumoniae CGSP14 6218052 YP_001836611.1 CDS SPCG_1894 NC_010582.1 1880594 1881415 R ABC transporter permease complement(1880594..1881415) Streptococcus pneumoniae CGSP14 6217142 YP_001836612.1 CDS SPCG_1895 NC_010582.1 1881432 1881548 R hypothetical protein complement(1881432..1881548) Streptococcus pneumoniae CGSP14 6216477 YP_001836613.1 CDS SPCG_1896 NC_010582.1 1881557 1881901 R MarR family transcriptional regulator complement(1881557..1881901) Streptococcus pneumoniae CGSP14 6217388 YP_001836614.1 CDS SPCG_1897 NC_010582.1 1882025 1882741 R hypothetical protein complement(1882025..1882741) Streptococcus pneumoniae CGSP14 6217183 YP_001836615.1 CDS ply NC_010582.1 1883622 1885037 R pneumolysin complement(1883622..1885037) Streptococcus pneumoniae CGSP14 6217360 YP_001836616.1 CDS SPCG_1899 NC_010582.1 1885048 1885458 R hypothetical protein complement(1885048..1885458) Streptococcus pneumoniae CGSP14 6216542 YP_001836617.1 CDS SPCG_1900 NC_010582.1 1885451 1886059 R hypothetical protein complement(1885451..1886059) Streptococcus pneumoniae CGSP14 6217538 YP_001836618.1 CDS SPCG_1901 NC_010582.1 1886072 1886548 R hypothetical protein complement(1886072..1886548) Streptococcus pneumoniae CGSP14 6217759 YP_001836619.1 CDS SPCG_1902 NC_010582.1 1886655 1886786 D degenerate transposase 1886655..1886786 Streptococcus pneumoniae CGSP14 6218288 YP_001836620.1 CDS SPCG_1903 NC_010582.1 1886791 1887054 D degenerate transposase 1886791..1887054 Streptococcus pneumoniae CGSP14 6218171 YP_001836621.1 CDS SPCG_1904 NC_010582.1 1887819 1888079 R hypothetical protein complement(1887819..1888079) Streptococcus pneumoniae CGSP14 6218242 YP_001836622.1 CDS SPCG_1905 NC_010582.1 1888138 1888692 R hypothetical protein complement(1888138..1888692) Streptococcus pneumoniae CGSP14 6216515 YP_001836623.1 CDS SPCG_1906 NC_010582.1 1888679 1888777 R hypothetical protein complement(1888679..1888777) Streptococcus pneumoniae CGSP14 6217228 YP_001836624.1 CDS SPCG_1907 NC_010582.1 1888839 1888937 R hypothetical protein complement(1888839..1888937) Streptococcus pneumoniae CGSP14 6218034 YP_001836625.1 CDS SPCG_1908 NC_010582.1 1888880 1889464 R hypothetical protein complement(1888880..1889464) Streptococcus pneumoniae CGSP14 6216827 YP_001836626.1 CDS SPCG_1909 NC_010582.1 1889872 1890297 R hypothetical protein complement(1889872..1890297) Streptococcus pneumoniae CGSP14 6217677 YP_001836627.1 CDS SPCG_1910 NC_010582.1 1890426 1890785 R hypothetical protein complement(1890426..1890785) Streptococcus pneumoniae CGSP14 6216625 YP_001836628.1 CDS SPCG_1965 NC_010582.1 1891024 1891185 R type II restriction-modification system regulatory protein complement(1891024..1891185) Streptococcus pneumoniae CGSP14 6216949 YP_001836629.1 CDS lytA NC_010582.1 1891531 1892487 R autolysin complement(1891531..1892487) Streptococcus pneumoniae CGSP14 6217991 YP_001836630.1 CDS dinF NC_010582.1 1892863 1894233 R MATE efflux family protein DinF complement(1892863..1894233) Streptococcus pneumoniae CGSP14 6216772 YP_001836631.1 CDS recA NC_010582.1 1894540 1895706 R catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A complement(1894540..1895706) Streptococcus pneumoniae CGSP14 6216804 YP_001836632.1 CDS cinA NC_010582.1 1895761 1897017 R competence damage-inducible protein A complement(1895761..1897017) Streptococcus pneumoniae CGSP14 6217299 YP_001836633.1 CDS lytR NC_010582.1 1897102 1898118 R transcriptional regulator complement(1897102..1898118) Streptococcus pneumoniae CGSP14 6217394 YP_001836634.1 CDS SPCG_1916 NC_010582.1 1898126 1898644 R acetyltransferase complement(1898126..1898644) Streptococcus pneumoniae CGSP14 6217886 YP_001836635.1 CDS SPCG_1917 NC_010582.1 1898634 1899077 R hypothetical protein complement(1898634..1899077) Streptococcus pneumoniae CGSP14 6218115 YP_001836636.1 CDS SPCG_1918 NC_010582.1 1899163 1899804 R hypothetical protein complement(1899163..1899804) Streptococcus pneumoniae CGSP14 6216757 YP_001836637.1 CDS plcR NC_010582.1 1900165 1901028 R transcriptional regulator PlcR complement(1900165..1901028) Streptococcus pneumoniae CGSP14 6216844 YP_001836638.1 CDS SPCG_1920 NC_010582.1 1901217 1901387 D hypothetical protein 1901217..1901387 Streptococcus pneumoniae CGSP14 6218015 YP_001836639.1 CDS SPCG_1921 NC_010582.1 1901837 1903852 D hypothetical protein 1901837..1903852 Streptococcus pneumoniae CGSP14 6217970 YP_001836640.1 CDS SPCG_1922 NC_010582.1 1903854 1904486 D ABC transporter ATP-binding protein 1903854..1904486 Streptococcus pneumoniae CGSP14 6218148 YP_001836641.1 CDS ndk NC_010582.1 1905432 1905845 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1905432..1905845) Streptococcus pneumoniae CGSP14 6216863 YP_001836642.1 CDS rpoC NC_010582.1 1905956 1909633 R DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter; DNA-directed RNA polymerase subunit beta' complement(1905956..1909633) Streptococcus pneumoniae CGSP14 6218086 YP_001836643.1 CDS SPCG_1925 NC_010582.1 1909666 1912140 R hypothetical protein complement(1909666..1912140) Streptococcus pneumoniae CGSP14 6217608 YP_001836644.1 CDS SPCG_1926 NC_010582.1 1912182 1913315 R hypothetical protein complement(1912182..1913315) Streptococcus pneumoniae CGSP14 6216737 YP_001836645.1 CDS SPCG_1927 NC_010582.1 1913732 1913839 D hypothetical protein 1913732..1913839 Streptococcus pneumoniae CGSP14 6216579 YP_001836646.1 CDS SPCG_1928 NC_010582.1 1913960 1915291 R hypothetical protein complement(1913960..1915291) Streptococcus pneumoniae CGSP14 6218229 YP_001836647.1 CDS endA NC_010582.1 1915582 1916406 R DNA-entry nuclease complement(1915582..1916406) Streptococcus pneumoniae CGSP14 6217192 YP_001836648.1 CDS murA NC_010582.1 1916626 1917909 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(1916626..1917909) Streptococcus pneumoniae CGSP14 6217527 YP_001836649.1 CDS SPCG_1931 NC_010582.1 1918221 1919258 R hypothetical protein complement(1918221..1919258) Streptococcus pneumoniae CGSP14 6217401 YP_001836650.1 CDS coaD NC_010582.1 1919242 1919730 R Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase complement(1919242..1919730) Streptococcus pneumoniae CGSP14 6216503 YP_001836651.1 CDS SPCG_1933 NC_010582.1 1919720 1920259 R type II DNA modification methyltransferase complement(1919720..1920259) Streptococcus pneumoniae CGSP14 6217800 YP_001836652.1 CDS asnA NC_010582.1 1920324 1921316 R catalyzes the formation of asparagine from aspartate and ammonia; asparagine synthetase AsnA complement(1920324..1921316) Streptococcus pneumoniae CGSP14 6216841 YP_001836653.1 CDS SPCG_1935 NC_010582.1 1921290 1921454 D hypothetical protein 1921290..1921454 Streptococcus pneumoniae CGSP14 6217153 YP_001836654.1 CDS SPCG_1936 NC_010582.1 1921428 1922135 R membrane protein complement(1921428..1922135) Streptococcus pneumoniae CGSP14 6217372 YP_001836655.1 CDS SPCG_1937 NC_010582.1 1922167 1922925 R spoU rRNA methylase family protein complement(1922167..1922925) Streptococcus pneumoniae CGSP14 6217280 YP_001836656.1 CDS acyP NC_010582.1 1922941 1923219 D catalyzes the hydrolysis of acylphosphate; acylphosphatase 1922941..1923219 Streptococcus pneumoniae CGSP14 6216460 YP_001836657.1 CDS SPCG_1939 NC_010582.1 1923297 1924223 D involved in biogenesis of membrane proteins; Firmicutes specific proteins are shorter than other bacterial counterparts and have a signal peptide and lipid attachment site; OxaA-like protein precursor 1923297..1924223 Streptococcus pneumoniae CGSP14 6218064 YP_001836658.1 CDS pflC NC_010582.1 1924298 1925092 R pyruvate formate-lyase-activating enzyme complement(1924298..1925092) Streptococcus pneumoniae CGSP14 6217824 YP_001836659.1 CDS lysA NC_010582.1 1925218 1926468 R diaminopimelate decarboxylase complement(1925218..1926468) Streptococcus pneumoniae CGSP14 6217383 YP_001836660.1 CDS purR NC_010582.1 1926535 1927362 R pur operon repressor complement(1926535..1927362) Streptococcus pneumoniae CGSP14 6218571 YP_001836661.1 CDS cbf1 NC_010582.1 1927629 1928633 R cmp-binding-factor 1 complement(1927629..1928633) Streptococcus pneumoniae CGSP14 6216488 YP_001836662.1 CDS SPCG_1944 NC_010582.1 1928560 1929858 R competence-induced protein Ccs50 complement(1928560..1929858) Streptococcus pneumoniae CGSP14 6216462 YP_001836663.1 CDS SPCG_1945 NC_010582.1 1929818 1930501 R hypothetical protein complement(1929818..1930501) Streptococcus pneumoniae CGSP14 6216518 YP_001836664.1 CDS rpe NC_010582.1 1930443 1931162 R ribulose-phosphate 3-epimerase complement(1930443..1931162) Streptococcus pneumoniae CGSP14 6217356 YP_001836665.1 CDS SPCG_1947 NC_010582.1 1931110 1931988 R EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity; ribosome-associated GTPase complement(1931110..1931988) Streptococcus pneumoniae CGSP14 6216494 YP_001836666.1 CDS ksgA NC_010582.1 1931990 1932862 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(1931990..1932862) Streptococcus pneumoniae CGSP14 6216933 YP_001836667.1 CDS SPCG_1949 NC_010582.1 1932993 1933307 R hypothetical protein complement(1932993..1933307) Streptococcus pneumoniae CGSP14 6216342 YP_001836668.1 CDS SPCG_1950 NC_010582.1 1933294 1933935 R ABC transporter ATP-binding protein complement(1933294..1933935) Streptococcus pneumoniae CGSP14 6218233 YP_001836669.1 CDS SPCG_1951 NC_010582.1 1933937 1935979 R immunity protein complement(1933937..1935979) Streptococcus pneumoniae CGSP14 6216508 YP_001836670.1 CDS SPCG_1952 NC_010582.1 1936044 1936340 R hypothetical protein complement(1936044..1936340) Streptococcus pneumoniae CGSP14 6217179 YP_001836671.1 CDS plcR NC_010582.1 1936660 1937559 R transcriptional regulator PlcR complement(1936660..1937559) Streptococcus pneumoniae CGSP14 6216846 YP_001836672.1 CDS SPCG_1954 NC_010582.1 1937631 1938191 R primase-like protein complement(1937631..1938191) Streptococcus pneumoniae CGSP14 6217014 YP_001836673.1 CDS SPCG_1955 NC_010582.1 1938191 1938964 R hydrolase complement(1938191..1938964) Streptococcus pneumoniae CGSP14 6217177 YP_001836674.1 CDS SPCG_1956 NC_010582.1 1939161 1939253 D hypothetical protein 1939161..1939253 Streptococcus pneumoniae CGSP14 6216669 YP_001836675.1 CDS SPCG_1957 NC_010582.1 1939269 1940168 R cell wall surface anchor family protein complement(1939269..1940168) Streptococcus pneumoniae CGSP14 6218102 YP_001836676.1 CDS rpmH NC_010582.1 1940452 1940586 R in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 complement(1940452..1940586) Streptococcus pneumoniae CGSP14 6218285 YP_001836677.1 CDS aspC NC_010582.1 1940731 1941945 R broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor; aminotransferase AlaT complement(1940731..1941945) Streptococcus pneumoniae CGSP14 6217251 YP_001836678.1 CDS SPCG_1960 NC_010582.1 1942101 1942409 R hypothetical protein complement(1942101..1942409) Streptococcus pneumoniae CGSP14 6216576 YP_001836679.1 CDS SPCG_1961 NC_010582.1 1942493 1943008 D universal stress protein 1942493..1943008 Streptococcus pneumoniae CGSP14 6216977 YP_001836680.1 CDS SPCG_1962 NC_010582.1 1943043 1944461 R cof family protein complement(1943043..1944461) Streptococcus pneumoniae CGSP14 6216803 YP_001836681.1 CDS ansB NC_010582.1 1944497 1945459 D L-asparaginase 1944497..1945459 Streptococcus pneumoniae CGSP14 6217728 YP_001836682.1 CDS ccpA NC_010582.1 1945755 1946795 R catabolite control protein A complement(1945755..1946795) Streptococcus pneumoniae CGSP14 6216676 YP_001836683.1 CDS SPCG_1966 NC_010582.1 1947189 1947788 R DNA-binding response regulator complement(1947189..1947788) Streptococcus pneumoniae CGSP14 6218271 YP_001836684.1 CDS SPCG_1967 NC_010582.1 1947789 1948886 R sensor histidine kinase complement(1947789..1948886) Streptococcus pneumoniae CGSP14 6216611 YP_001836685.1 CDS SPCG_1968 NC_010582.1 1948886 1949689 R hypothetical protein complement(1948886..1949689) Streptococcus pneumoniae CGSP14 6216964 YP_001836686.1 CDS SPCG_1969 NC_010582.1 1949625 1950509 R ABC transporter ATP-binding protein complement(1949625..1950509) Streptococcus pneumoniae CGSP14 6216517 YP_001836687.1 CDS SPCG_1970 NC_010582.1 1950496 1950690 R hypothetical protein complement(1950496..1950690) Streptococcus pneumoniae CGSP14 6217924 YP_001836688.1 CDS SPCG_1971 NC_010582.1 1950777 1950893 R hypothetical protein complement(1950777..1950893) Streptococcus pneumoniae CGSP14 6217978 YP_001836689.1 CDS comX2 NC_010582.1 1957572 1958051 R competence-specific global transcription modulator complement(1957572..1958051) Streptococcus pneumoniae CGSP14 6217616 YP_001836690.1 CDS nusG NC_010582.1 1958173 1958724 R Modulates Rho-dependent transcription termination; transcription antitermination protein NusG complement(1958173..1958724) Streptococcus pneumoniae CGSP14 6218156 YP_001836691.1 CDS secE NC_010582.1 1958764 1958940 R forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE complement(1958764..1958940) Streptococcus pneumoniae CGSP14 6217293 YP_001836692.1 CDS SPCG_1975 NC_010582.1 1959245 1960516 D IS1202 transposase 1959245..1960516 Streptococcus pneumoniae CGSP14 6216626 YP_001836693.1 CDS pbp2A NC_010582.1 1960934 1963129 R penicillin-binding protein 2A complement(1960934..1963129) Streptococcus pneumoniae CGSP14 6218175 YP_001836694.1 CDS rluD NC_010582.1 1963216 1964091 D ribosomal large subunit pseudouridine synthase D 1963216..1964091 Streptococcus pneumoniae CGSP14 6218006 YP_001836695.1 CDS SPCG_1978 NC_010582.1 1964197 1965489 D IS1167, transposase 1964197..1965489 Streptococcus pneumoniae CGSP14 6217495 YP_001836696.1 CDS gapA NC_010582.1 1965579 1966658 R glyceraldehyde-3-phosphate dehydrogenase complement(1965579..1966658) Streptococcus pneumoniae CGSP14 6217456 YP_001836697.1 CDS SPCG_1980 NC_010582.1 1966806 1967765 R hypothetical protein complement(1966806..1967765) Streptococcus pneumoniae CGSP14 6217581 YP_001836698.1 CDS SPCG_1981 NC_010582.1 1967851 1968189 R IS630-Spn1, transposase Orf2 complement(1967851..1968189) Streptococcus pneumoniae CGSP14 6217655 YP_001836699.1 CDS SPCG_1982 NC_010582.1 1968347 1968715 R IS630-Spn1, transposase Orf1 complement(1968347..1968715) Streptococcus pneumoniae CGSP14 6217983 YP_001836700.1 CDS nadC NC_010582.1 1968828 1969727 R catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; nicotinate-nucleotide pyrophosphorylase complement(1968828..1969727) Streptococcus pneumoniae CGSP14 6217817 YP_001836701.1 CDS SPCG_1984 NC_010582.1 1969937 1971247 D membrane protein 1969937..1971247 Streptococcus pneumoniae CGSP14 6218099 YP_001836702.1 CDS SPCG_1985 NC_010582.1 1971629 1971823 R hypothetical protein complement(1971629..1971823) Streptococcus pneumoniae CGSP14 6217944 YP_001836703.1 CDS SPCG_1986 NC_010582.1 1972283 1973011 R GntR family transcriptional regulator complement(1972283..1973011) Streptococcus pneumoniae CGSP14 6216610 YP_001836704.1 CDS SPCG_1987 NC_010582.1 1973127 1974578 D glycosyl hydrolase family protein 1973127..1974578 Streptococcus pneumoniae CGSP14 6218254 YP_001836705.1 CDS SPCG_1988 NC_010582.1 1974596 1975891 D PTS system transporter subunit IIC 1974596..1975891 Streptococcus pneumoniae CGSP14 6217547 YP_001836706.1 CDS SPCG_1989 NC_010582.1 1975857 1976204 D PTS system transporter subunit IIB 1975857..1976204 Streptococcus pneumoniae CGSP14 6218262 YP_001836707.1 CDS SPCG_1990 NC_010582.1 1976183 1976509 D PTS system transporter subunit IIA 1976183..1976509 Streptococcus pneumoniae CGSP14 6216835 YP_001836708.1 CDS adhE NC_010582.1 1977495 1980167 R bifunctional acetaldehyde-CoA/alcohol dehydrogenase complement(1977495..1980167) Streptococcus pneumoniae CGSP14 6218220 YP_001836709.1 CDS SPCG_1992 NC_010582.1 1980446 1980856 R hypothetical protein complement(1980446..1980856) Streptococcus pneumoniae CGSP14 6217700 YP_001836710.1 CDS SPCG_1993 NC_010582.1 1980858 1981286 R phosphotyrosine protein phosphatase complement(1980858..1981286) Streptococcus pneumoniae CGSP14 6217267 YP_001836711.1 CDS yajC NC_010582.1 1981333 1981632 R member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex; preprotein translocase subunit YajC complement(1981333..1981632) Streptococcus pneumoniae CGSP14 6218203 YP_001836712.1 CDS tktA NC_010582.1 1981749 1983725 R catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase; transketolase complement(1981749..1983725) Streptococcus pneumoniae CGSP14 6217649 YP_001836713.1 CDS SPCG_1996 NC_010582.1 1983839 1984930 R L-ascorbate 6-phosphate lactonase complement(1983839..1984930) Streptococcus pneumoniae CGSP14 6217873 YP_001836714.1 CDS SPCG_1997 NC_010582.1 1985042 1986715 R BglG family transcriptional regulator complement(1985042..1986715) Streptococcus pneumoniae CGSP14 6218291 YP_001836715.1 CDS araD NC_010582.1 1986894 1987598 R catalyzes the formation of D-xylulose 5-phosphate from L-ribulose 5-phosphate in the L-arabinose and L-ascorbate degradation pathways; L-ribulose-5-phosphate 4-epimerase complement(1986894..1987598) Streptococcus pneumoniae CGSP14 6218178 YP_001836716.1 CDS SPCG_1999 NC_010582.1 1987600 1988061 R hexulose-6-phosphate isomerase complement(1987600..1988061) Streptococcus pneumoniae CGSP14 6217253 YP_001836717.1 CDS SPCG_2000 NC_010582.1 1988102 1988458 R hexulose-6-phosphate isomerase complement(1988102..1988458) Streptococcus pneumoniae CGSP14 6218154 YP_001836718.1 CDS ulaD NC_010582.1 1988462 1989127 R catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization; 3-keto-L-gulonate-6-phosphate decarboxylase complement(1988462..1989127) Streptococcus pneumoniae CGSP14 6217479 YP_001836719.1 CDS SPCG_2002 NC_010582.1 1989144 1989629 R PTS system transporter subunit IIA complement(1989144..1989629) Streptococcus pneumoniae CGSP14 6217346 YP_001836720.1 CDS SPCG_2003 NC_010582.1 1989706 1989987 R PTS system transporter subunit IIB complement(1989706..1989987) Streptococcus pneumoniae CGSP14 6218255 YP_001836721.1 CDS ulaA NC_010582.1 1990010 1991536 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(1990010..1991536) Streptococcus pneumoniae CGSP14 6217829 YP_001836722.1 CDS SPCG_2005 NC_010582.1 1991598 1992221 R hypothetical protein complement(1991598..1992221) Streptococcus pneumoniae CGSP14 6218038 YP_001836723.1 CDS SPCG_2006 NC_010582.1 1992272 1993258 R jag protein complement(1992272..1993258) Streptococcus pneumoniae CGSP14 6217507 YP_001836724.1 CDS SPCG_2007 NC_010582.1 1993277 1994107 R spoIIIJ family protein complement(1993277..1994107) Streptococcus pneumoniae CGSP14 6218177 YP_001836725.1 CDS rnpA NC_010582.1 1994076 1994447 R protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates; ribonuclease P complement(1994076..1994447) Streptococcus pneumoniae CGSP14 6217901 YP_001836726.1 CDS SPCG_2009 NC_010582.1 1994464 1994595 R hypothetical protein complement(1994464..1994595) Streptococcus pneumoniae CGSP14 6216703 YP_001836727.1 CDS SPCG_2010 NC_010582.1 1994596 1995816 R AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA; acetate kinase complement(1994596..1995816) Streptococcus pneumoniae CGSP14 6216608 YP_001836728.1 CDS SPCG_2011 NC_010582.1 1995837 1996790 R hypothetical protein complement(1995837..1996790) Streptococcus pneumoniae CGSP14 6217994 YP_001836729.1 CDS SPCG_2012 NC_010582.1 1996851 1997231 R hypothetical protein complement(1996851..1997231) Streptococcus pneumoniae CGSP14 6218243 YP_001836730.1 CDS SPCG_2013 NC_010582.1 1997263 1997445 R hypothetical protein complement(1997263..1997445) Streptococcus pneumoniae CGSP14 6216333 YP_001836731.1 CDS SPCG_2014 NC_010582.1 1997548 1997994 R hypothetical protein complement(1997548..1997994) Streptococcus pneumoniae CGSP14 6217241 YP_001836732.1 CDS SPCG_2015 NC_010582.1 1997972 1998379 R hypothetical protein complement(1997972..1998379) Streptococcus pneumoniae CGSP14 6217681 YP_001836733.1 CDS SPCG_2016 NC_010582.1 1998396 1998656 R hypothetical protein complement(1998396..1998656) Streptococcus pneumoniae CGSP14 6217598 YP_001836734.1 CDS cglD NC_010582.1 1998661 1999089 R competence protein CglD complement(1998661..1999089) Streptococcus pneumoniae CGSP14 6218222 YP_001836735.1 CDS cglC NC_010582.1 1999058 1999384 R competence protein CglC complement(1999058..1999384) Streptococcus pneumoniae CGSP14 6218121 YP_001836736.1 CDS cglB NC_010582.1 1999386 2000429 R competence protein CglB complement(1999386..2000429) Streptococcus pneumoniae CGSP14 6217904 YP_001836737.1 CDS cglA NC_010582.1 2000350 2001291 R competence protein CglA complement(2000350..2001291) Streptococcus pneumoniae CGSP14 6217902 YP_001836738.1 CDS SPCG_2021 NC_010582.1 2001367 2001738 R hypothetical protein complement(2001367..2001738) Streptococcus pneumoniae CGSP14 6217832 YP_001836739.1 CDS adh NC_010582.1 2001883 2002941 R zinc-containing alcohol dehydrogenase complement(2001883..2002941) Streptococcus pneumoniae CGSP14 6217891 YP_001836740.1 CDS nagA NC_010582.1 2003104 2004255 R N-acetylglucosamine-6-phosphate deacetylase complement(2003104..2004255) Streptococcus pneumoniae CGSP14 6217147 YP_001836741.1 CDS SPCG_2024 NC_010582.1 2004408 2006225 R hypothetical protein complement(2004408..2006225) Streptococcus pneumoniae CGSP14 6218301 YP_001836742.1 CDS tgt NC_010582.1 2006326 2007468 R Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr); queuine tRNA-ribosyltransferase complement(2006326..2007468) Streptococcus pneumoniae CGSP14 6217333 YP_001836743.1 CDS SPCG_2026 NC_010582.1 2007598 2008455 D hypothetical protein 2007598..2008455 Streptococcus pneumoniae CGSP14 6217860 YP_001836744.1 CDS SPCG_2027 NC_010582.1 2008483 2009127 R catalyzes the removal of 5-oxoproline from various penultimate amino acid residues except L-proline; pyrrolidone-carboxylate peptidase complement(2008483..2009127) Streptococcus pneumoniae CGSP14 6218261 YP_001836745.1 CDS SPCG_2028 NC_010582.1 2009234 2009593 R hypothetical protein complement(2009234..2009593) Streptococcus pneumoniae CGSP14 6217508 YP_001836746.1 CDS marR NC_010582.1 2009604 2010029 R MarR family transcriptional regulator complement(2009604..2010029) Streptococcus pneumoniae CGSP14 6217840 YP_001836747.1 CDS SPCG_2030 NC_010582.1 2010349 2011461 R lysM domain-containing protein complement(2010349..2011461) Streptococcus pneumoniae CGSP14 6217820 YP_001836748.1 CDS SPCG_2031 NC_010582.1 2011627 2012247 R HAD superfamily hydrolase complement(2011627..2012247) Streptococcus pneumoniae CGSP14 6217835 YP_001836749.1 CDS SPCG_2032 NC_010582.1 2012251 2013531 R MATE efflux family protein complement(2012251..2013531) Streptococcus pneumoniae CGSP14 6218071 YP_001836750.1 CDS thrC NC_010582.1 2013592 2015076 R catalyzes the formation of L-threonine from O-phospho-L-homoserine; threonine synthase complement(2013592..2015076) Streptococcus pneumoniae CGSP14 6218134 YP_001836751.1 CDS SPCG_2034 NC_010582.1 2015152 2016429 R hypothetical protein complement(2015152..2016429) Streptococcus pneumoniae CGSP14 6218212 YP_001836752.1 CDS SPCG_2035 NC_010582.1 2022891 2023325 R cytidine/deoxycytidylate deaminase family protein complement(2022891..2023325) Streptococcus pneumoniae CGSP14 6218067 YP_001836753.1 CDS gltX NC_010582.1 2023339 2024799 R Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase complement(2023339..2024799) Streptococcus pneumoniae CGSP14 6217819 YP_001836754.1 CDS pgi NC_010582.1 2024923 2026272 R functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; glucose-6-phosphate isomerase complement(2024923..2026272) Streptococcus pneumoniae CGSP14 6218183 YP_001836755.1 CDS SPCG_2038 NC_010582.1 2026259 2026438 R hypothetical protein complement(2026259..2026438) Streptococcus pneumoniae CGSP14 6217144 YP_001836756.1 CDS guaA NC_010582.1 2026442 2027179 R glutamine amidotransferase, class-I complement(2026442..2027179) Streptococcus pneumoniae CGSP14 6218044 YP_001836757.1 CDS SPCG_2040 NC_010582.1 2027270 2029081 R ABC transporter ATP-binding protein/permease complement(2027270..2029081) Streptococcus pneumoniae CGSP14 6218192 YP_001836758.1 CDS SPCG_2041 NC_010582.1 2029183 2029497 D degenerate transposase 2029183..2029497 Streptococcus pneumoniae CGSP14 6216869 YP_001836759.1 CDS SPCG_2042 NC_010582.1 2029828 2031522 R ABC transporter ATP-binding protein/permease complement(2029828..2031522) Streptococcus pneumoniae CGSP14 6217184 YP_001836760.1 CDS hexA NC_010582.1 2031669 2034242 R This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS complement(2031669..2034242) Streptococcus pneumoniae CGSP14 6217823 YP_001836761.1 CDS argR NC_010582.1 2034254 2034700 R transcriptional repressor complement(2034254..2034700) Streptococcus pneumoniae CGSP14 6218047 YP_001836762.1 CDS argS NC_010582.1 2034836 2036527 D catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 2034836..2036527 Streptococcus pneumoniae CGSP14 6217861 YP_001836763.1 CDS SPCG_2046 NC_010582.1 2036842 2037231 R IS1381 transposase protein B complement(2036842..2037231) Streptococcus pneumoniae CGSP14 6217985 YP_001836764.1 CDS SPCG_2047 NC_010582.1 2037362 2037871 D hypothetical protein 2037362..2037871 Streptococcus pneumoniae CGSP14 6218264 YP_001836765.1 CDS SPCG_2048 NC_010582.1 2037955 2038665 D response regulator 2037955..2038665 Streptococcus pneumoniae CGSP14 6216855 YP_001836766.1 CDS SPCG_2049 NC_010582.1 2038662 2039993 D sensor histidine kinase PnpS 2038662..2039993 Streptococcus pneumoniae CGSP14 6217588 YP_001836767.1 CDS SPCG_2050 NC_010582.1 2040097 2041035 D phosphate ABC transporter substrate-binding protein 2040097..2041035 Streptococcus pneumoniae CGSP14 6217900 YP_001836768.1 CDS SPCG_2051 NC_010582.1 2041153 2042016 D phosphate ABC transporter permease 2041153..2042016 Streptococcus pneumoniae CGSP14 6218132 YP_001836769.1 CDS SPCG_2052 NC_010582.1 2042009 2042824 D phosphate ABC transporter permease 2042009..2042824 Streptococcus pneumoniae CGSP14 6217856 YP_001836770.1 CDS SPCG_2053 NC_010582.1 2042826 2043578 D ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate transporter ATP-binding protein 2042826..2043578 Streptococcus pneumoniae CGSP14 6217541 YP_001836771.1 CDS phoU NC_010582.1 2043593 2044243 D phosphate transport system regulatory protein PhoU 2043593..2044243 Streptococcus pneumoniae CGSP14 6217656 YP_001836772.1 CDS SPCG_2055 NC_010582.1 2044311 2044736 D degenerate transposase 2044311..2044736 Streptococcus pneumoniae CGSP14 6217898 YP_001836773.1 CDS SPCG_2056 NC_010582.1 2044910 2045368 R transcriptional regulator complement(2044910..2045368) Streptococcus pneumoniae CGSP14 6217472 YP_001836774.1 CDS gpsA NC_010582.1 2045502 2046518 D catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate; NAD(P)H-dependent glycerol-3-phosphate dehydrogenase 2045502..2046518 Streptococcus pneumoniae CGSP14 6216735 YP_001836775.1 CDS galU NC_010582.1 2046540 2047439 D UTP-glucose-1-phosphate uridylyltransferase 2046540..2047439 Streptococcus pneumoniae CGSP14 6218025 YP_001836776.1 CDS SPCG_2059 NC_010582.1 2047506 2048186 R hypothetical protein complement(2047506..2048186) Streptococcus pneumoniae CGSP14 6216919 YP_001836777.1 CDS SPCG_2060 NC_010582.1 2048167 2048712 R 5-formyltetrahydrofolate cyclo-ligase complement(2048167..2048712) Streptococcus pneumoniae CGSP14 6217941 YP_001836778.1 CDS SPCG_2061 NC_010582.1 2048718 2049848 R M20/M25/M40 family peptidase complement(2048718..2049848) Streptococcus pneumoniae CGSP14 6218235 YP_001836779.1 CDS SPCG_2062 NC_010582.1 2049916 2050614 R 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase complement(2049916..2050614) Streptococcus pneumoniae CGSP14 6217467 YP_001836780.1 CDS SPCG_2063 NC_010582.1 2050844 2051929 R hypothetical protein complement(2050844..2051929) Streptococcus pneumoniae CGSP14 6217695 YP_001836781.1 CDS pbp1B NC_010582.1 2051820 2054297 R penicillin-binding protein 1B complement(2051820..2054297) Streptococcus pneumoniae CGSP14 6217798 YP_001836782.1 CDS tyrS NC_010582.1 2054427 2055683 D catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr); tyrosyl-tRNA synthetase 2054427..2055683 Streptococcus pneumoniae CGSP14 6217431 YP_001836783.1 CDS ctpC NC_010582.1 2055761 2057833 R cation transporter E1-E2 family ATPase complement(2055761..2057833) Streptococcus pneumoniae CGSP14 6217908 YP_001836784.1 CDS SPCG_2067 NC_010582.1 2057826 2058137 R hypothetical protein complement(2057826..2058137) Streptococcus pneumoniae CGSP14 6218110 YP_001836785.1 CDS rrmA NC_010582.1 2058256 2059104 D rRNA (guanine-N1-)-methyltransferase 2058256..2059104 Streptococcus pneumoniae CGSP14 6217116 YP_001836786.1 CDS SPCG_2069 NC_010582.1 2059727 2060299 D hypothetical protein 2059727..2060299 Streptococcus pneumoniae CGSP14 6217946 YP_001836787.1 CDS malP NC_010582.1 2061344 2063602 R glycogen phosphorylase family protein complement(2061344..2063602) Streptococcus pneumoniae CGSP14 6217471 YP_001836788.1 CDS malM NC_010582.1 2063628 2065145 R amylomaltase; acts to release glucose from maltodextrins; 4-alpha-glucanotransferase complement(2063628..2065145) Streptococcus pneumoniae CGSP14 6217466 YP_001836789.1 CDS SPCG_2072 NC_010582.1 2065614 2066966 D maltose/maltodextrin ABC transporter maltose/maltodextrin-binding protein 2065614..2066966 Streptococcus pneumoniae CGSP14 6217619 YP_001836790.1 CDS SPCG_2073 NC_010582.1 2067062 2068369 D maltodextrin ABC transporter permease 2067062..2068369 Streptococcus pneumoniae CGSP14 6217668 YP_001836791.1 CDS SPCG_2074 NC_010582.1 2068350 2069213 D maltodextrin ABC transporter permease 2068350..2069213 Streptococcus pneumoniae CGSP14 6218090 YP_001836792.1 CDS malA NC_010582.1 2069466 2070266 D malA protein 2069466..2070266 Streptococcus pneumoniae CGSP14 6217405 YP_001836793.1 CDS malR NC_010582.1 2070276 2071262 D maltose operon transcriptional repressor 2070276..2071262 Streptococcus pneumoniae CGSP14 6218142 YP_001836794.1 CDS SPCG_2077 NC_010582.1 2071311 2071646 D hypothetical protein 2071311..2071646 Streptococcus pneumoniae CGSP14 6218051 YP_001836795.1 CDS SPCG_2078 NC_010582.1 2071688 2072629 R hypothetical protein complement(2071688..2072629) Streptococcus pneumoniae CGSP14 6217828 YP_001836796.1 CDS aspS NC_010582.1 2072607 2074370 R catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes; aspartyl-tRNA synthetase complement(2072607..2074370) Streptococcus pneumoniae CGSP14 6217537 YP_001836797.1 CDS SPCG_2080 NC_010582.1 2074489 2074680 R hypothetical protein complement(2074489..2074680) Streptococcus pneumoniae CGSP14 6217672 YP_001836798.1 CDS SPCG_2081 NC_010582.1 2074722 2074952 R hypothetical protein complement(2074722..2074952) Streptococcus pneumoniae CGSP14 6218081 YP_001836799.1 CDS SPCG_2082 NC_010582.1 2074970 2075611 R hypothetical protein complement(2074970..2075611) Streptococcus pneumoniae CGSP14 6216521 YP_001836800.1 CDS SPCG_2083 NC_010582.1 2075623 2076351 R hypothetical protein complement(2075623..2076351) Streptococcus pneumoniae CGSP14 6217919 YP_001836801.1 CDS SPCG_2084 NC_010582.1 2076348 2076548 R hypothetical protein complement(2076348..2076548) Streptococcus pneumoniae CGSP14 6218072 YP_001836802.1 CDS SPCG_2085 NC_010582.1 2076545 2076760 R transcriptional regulator complement(2076545..2076760) Streptococcus pneumoniae CGSP14 6216836 YP_001836803.1 CDS SPCG_2086 NC_010582.1 2076761 2077228 R hypothetical protein complement(2076761..2077228) Streptococcus pneumoniae CGSP14 6217699 YP_001836804.1 CDS SPCG_2087 NC_010582.1 2077228 2077401 R hypothetical protein complement(2077228..2077401) Streptococcus pneumoniae CGSP14 6217865 YP_001836805.1 CDS hisS NC_010582.1 2077461 2078750 R catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase complement(2077461..2078750) Streptococcus pneumoniae CGSP14 6218101 YP_001836806.1 CDS SPCG_2089 NC_010582.1 2078828 2080075 R hypothetical protein complement(2078828..2080075) Streptococcus pneumoniae CGSP14 6217885 YP_001836807.1 CDS SPCG_2090 NC_010582.1 2080292 2081638 D IS1380-Spn1 transposase 2080292..2081638 Streptococcus pneumoniae CGSP14 6217948 YP_001836808.1 CDS SPCG_2091 NC_010582.1 2081974 2082825 R transcriptional regulator MutR complement(2081974..2082825) Streptococcus pneumoniae CGSP14 6218234 YP_001836809.1 CDS SPCG_2092 NC_010582.1 2082800 2082934 R hypothetical protein complement(2082800..2082934) Streptococcus pneumoniae CGSP14 6217962 YP_001836810.1 CDS SPCG_2093 NC_010582.1 2082949 2083290 D hypothetical protein 2082949..2083290 Streptococcus pneumoniae CGSP14 6217517 YP_001836811.1 CDS SPCG_2094 NC_010582.1 2083354 2083518 D histidyl-tRNA synthetase 2083354..2083518 Streptococcus pneumoniae CGSP14 6217949 YP_001836812.1 CDS ilvD NC_010582.1 2083544 2085247 R catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; dihydroxy-acid dehydratase complement(2083544..2085247) Streptococcus pneumoniae CGSP14 6217841 YP_001836813.1 CDS tktC NC_010582.1 2085480 2086412 R transketolase, C-terminal subunit complement(2085480..2086412) Streptococcus pneumoniae CGSP14 6217235 YP_001836814.1 CDS tktN NC_010582.1 2086409 2087266 R transketolase complement(2086409..2087266) Streptococcus pneumoniae CGSP14 6217603 YP_001836815.1 CDS ulaA NC_010582.1 2087270 2088616 R membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr; PTS system ascorbate-specific transporter subunit IIC complement(2087270..2088616) Streptococcus pneumoniae CGSP14 6217761 YP_001836816.1 CDS SPCG_2099 NC_010582.1 2088629 2088913 R PTS system transporter subunit IIB complement(2088629..2088913) Streptococcus pneumoniae CGSP14 6218207 YP_001836817.1 CDS SPCG_2100 NC_010582.1 2088917 2090947 R BglG family transcriptional regulator complement(2088917..2090947) Streptococcus pneumoniae CGSP14 6217496 YP_001836818.1 CDS SPCG_2101 NC_010582.1 2091138 2092145 D hypothetical protein 2091138..2092145 Streptococcus pneumoniae CGSP14 6218009 YP_001836819.1 CDS SPCG_2102 NC_010582.1 2092148 2092348 D hypothetical protein 2092148..2092348 Streptococcus pneumoniae CGSP14 6216496 YP_001836820.1 CDS rpmF NC_010582.1 2092500 2092682 D some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 2092500..2092682 Streptococcus pneumoniae CGSP14 6217514 YP_001836821.1 CDS rpmG NC_010582.1 2092698 2092847 D in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 2092698..2092847 Streptococcus pneumoniae CGSP14 6216850 YP_001836822.1 CDS pcpA NC_010582.1 2093339 2095324 R choline binding protein PcpA complement(2093339..2095324) Streptococcus pneumoniae CGSP14 6216902 YP_001836823.1 CDS SPCG_2106 NC_010582.1 2095659 2095841 D degenerate transposase 2095659..2095841 Streptococcus pneumoniae CGSP14 6217076 YP_001836824.1 CDS SPCG_2107 NC_010582.1 2095912 2096229 D degenerate transposase 2095912..2096229 Streptococcus pneumoniae CGSP14 6217265 YP_001836825.1 CDS SPCG_2108 NC_010582.1 2096234 2096497 D degenerate transposase 2096234..2096497 Streptococcus pneumoniae CGSP14 6216516 YP_001836826.1 CDS SPCG_2109 NC_010582.1 2096567 2096893 R hypothetical protein complement(2096567..2096893) Streptococcus pneumoniae CGSP14 6216903 YP_001836827.1 CDS SPCG_2110 NC_010582.1 2097128 2097223 D hypothetical protein 2097128..2097223 Streptococcus pneumoniae CGSP14 6216573 YP_001836828.1 CDS SPCG_2111 NC_010582.1 2097307 2099187 R glycosyl hydrolase-like protein complement(2097307..2099187) Streptococcus pneumoniae CGSP14 6218425 YP_001836829.1 CDS SPCG_2112 NC_010582.1 2099181 2100062 R ROK family protein complement(2099181..2100062) Streptococcus pneumoniae CGSP14 6216551 YP_001836830.1 CDS SPCG_2113 NC_010582.1 2100134 2102794 R hypothetical protein complement(2100134..2102794) Streptococcus pneumoniae CGSP14 6216444 YP_001836831.1 CDS SPCG_2114 NC_010582.1 2102870 2104174 R hypothetical protein complement(2102870..2104174) Streptococcus pneumoniae CGSP14 6216747 YP_001836832.1 CDS SPCG_2115 NC_010582.1 2104152 2104247 D hypothetical protein 2104152..2104247 Streptococcus pneumoniae CGSP14 6216582 YP_001836833.1 CDS SPCG_2116 NC_010582.1 2104321 2106405 D cell wall antigen 2104321..2106405 Streptococcus pneumoniae CGSP14 6217090 YP_001836834.1 CDS SPCG_2117 NC_010582.1 2106445 2108196 R hypothetical protein complement(2106445..2108196) Streptococcus pneumoniae CGSP14 6216813 YP_001836835.1 CDS SPCG_2118 NC_010582.1 2108880 2110109 D catalyzes the degradation of arginine to citruline and ammonia; arginine deiminase 2108880..2110109 Streptococcus pneumoniae CGSP14 6216736 YP_001836836.1 CDS arcB NC_010582.1 2110167 2111183 D catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; ornithine carbamoyltransferase 2110167..2111183 Streptococcus pneumoniae CGSP14 6216904 YP_001836837.1 CDS arcC NC_010582.1 2111348 2112295 D catalyzes the reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; carbamate kinase 2111348..2112295 Streptococcus pneumoniae CGSP14 6217899 YP_001836838.1 CDS SPCG_2121 NC_010582.1 2112506 2114017 D hypothetical protein 2112506..2114017 Streptococcus pneumoniae CGSP14 6216814 YP_001836839.1 CDS SPCG_2122 NC_010582.1 2114039 2115370 D hypothetical protein 2114039..2115370 Streptococcus pneumoniae CGSP14 6216547 YP_001836840.1 CDS SPCG_2123 NC_010582.1 2115978 2116244 R hypothetical protein complement(2115978..2116244) Streptococcus pneumoniae CGSP14 6216702 YP_001836841.1 CDS SPCG_2124 NC_010582.1 2116583 2117482 R hypothetical protein complement(2116583..2117482) Streptococcus pneumoniae CGSP14 6216558 YP_001836842.1 CDS adh2 NC_010582.1 2117612 2118763 R iron-containing alcohol dehydrogenase complement(2117612..2118763) Streptococcus pneumoniae CGSP14 6217174 YP_001836843.1 CDS fucI NC_010582.1 2118909 2120675 R catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose; L-fucose isomerase complement(2118909..2120675) Streptococcus pneumoniae CGSP14 6216773 YP_001836844.1 CDS fucA NC_010582.1 2120688 2121416 R L-fuculose phosphate aldolase complement(2120688..2121416) Streptococcus pneumoniae CGSP14 6216613 YP_001836845.1 CDS SPCG_2128 NC_010582.1 2121431 2124517 R hypothetical protein complement(2121431..2124517) Streptococcus pneumoniae CGSP14 6216570 YP_001836846.1 CDS SPCG_2129 NC_010582.1 2124459 2126675 R alpha-galactosidase complement(2124459..2126675) Streptococcus pneumoniae CGSP14 6216946 YP_001836847.1 CDS SPCG_2130 NC_010582.1 2126697 2128568 R hypothetical protein complement(2126697..2128568) Streptococcus pneumoniae CGSP14 6216759 YP_001836848.1 CDS SPCG_2131 NC_010582.1 2128574 2129893 R glycosyl hydrolase complement(2128574..2129893) Streptococcus pneumoniae CGSP14 6216758 YP_001836849.1 CDS SPCG_2132 NC_010582.1 2129890 2130735 R sugar ABC transporter permease complement(2129890..2130735) Streptococcus pneumoniae CGSP14 6216719 YP_001836850.1 CDS SPCG_2133 NC_010582.1 2130732 2131718 R sugar ABC transporter permease complement(2130732..2131718) Streptococcus pneumoniae CGSP14 6217510 YP_001836851.1 CDS SPCG_2134 NC_010582.1 2131748 2133040 R sugar ABC transporter substrate-binding protein complement(2131748..2133040) Streptococcus pneumoniae CGSP14 6218137 YP_001836852.1 CDS fucK NC_010582.1 2133069 2134517 R L-fuculose kinase fucK complement(2133069..2134517) Streptococcus pneumoniae CGSP14 6217443 YP_001836853.1 CDS fcsR NC_010582.1 2134648 2135421 D fucose operon repressor 2134648..2135421 Streptococcus pneumoniae CGSP14 6217194 YP_001836854.1 CDS SPCG_2137 NC_010582.1 2136592 2138097 R zinc ABC transporter zinc-binding lipoprotein complement(2136592..2138097) Streptococcus pneumoniae CGSP14 6217119 YP_001836855.1 CDS SPCG_2138 NC_010582.1 2138107 2138937 R zinc ABC transporter permease complement(2138107..2138937) Streptococcus pneumoniae CGSP14 6218238 YP_001836856.1 CDS SPCG_2139 NC_010582.1 2138906 2139610 R zinc ABC transporter ATP-binding protein complement(2138906..2139610) Streptococcus pneumoniae CGSP14 6217760 YP_001836857.1 CDS adcR NC_010582.1 2139610 2140110 R adc operon repressor AdcR complement(2139610..2140110) Streptococcus pneumoniae CGSP14 6218479 YP_001836858.1 CDS dltD NC_010582.1 2140205 2141488 R dltD protein complement(2140205..2141488) Streptococcus pneumoniae CGSP14 6218393 YP_001836859.1 CDS dltC NC_010582.1 2141466 2141705 R D-alanyl carrier protein subunit; involved in the incorporation of D-alanine into membrane-associated D-alanyl-lipoteichoic acid; D-alanyl carrier protein is the acceptor of activated D-alanine which it donates to a membrane acceptor(D-alanyl transferase) for incorporation into membrane lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 2 complement(2141466..2141705) Streptococcus pneumoniae CGSP14 6217361 YP_001836860.1 CDS dltB NC_010582.1 2141719 2142963 R dltB protein complement(2141719..2142963) Streptococcus pneumoniae CGSP14 6218408 YP_001836861.1 CDS dltA NC_010582.1 2142960 2144690 R transfers D-alanine to the D-alanyl carrier protein during the incorporation of D-alanine into lipoteichoic acid; D-alanine--poly(phosphoribitol) ligase subunit 1 complement(2142960..2144690) Streptococcus pneumoniae CGSP14 6217792 YP_001836862.1 CDS SPCG_2145 NC_010582.1 2144711 2144845 R hypothetical protein complement(2144711..2144845) Streptococcus pneumoniae CGSP14 6217688 YP_001836863.1 CDS SPCG_2146 NC_010582.1 2145156 2146334 R hypothetical protein complement(2145156..2146334) Streptococcus pneumoniae CGSP14 6217635 YP_001836864.1 CDS SPCG_2147 NC_010582.1 2146794 2147786 R hypothetical protein complement(2146794..2147786) Streptococcus pneumoniae CGSP14 6217315 YP_001836865.1 CDS SPCG_2148 NC_010582.1 2147790 2148071 R hypothetical protein complement(2147790..2148071) Streptococcus pneumoniae CGSP14 6218035 YP_001836866.1 CDS SPCG_2149 NC_010582.1 2149111 2149770 D hypothetical protein 2149111..2149770 Streptococcus pneumoniae CGSP14 6216601 YP_001836867.1 CDS SPCG_2150 NC_010582.1 2149857 2150060 R hypothetical protein complement(2149857..2150060) Streptococcus pneumoniae CGSP14 6216686 YP_001836868.1 CDS SPCG_2151 NC_010582.1 2150153 2150254 D hypothetical protein 2150153..2150254 Streptococcus pneumoniae CGSP14 6217675 YP_001836869.1 CDS glpF NC_010582.1 2150251 2151009 R glycerol uptake facilitator protein complement(2150251..2151009) Streptococcus pneumoniae CGSP14 6218218 YP_001836870.1 CDS SPCG_2153 NC_010582.1 2151025 2152851 R hypothetical protein complement(2151025..2152851) Streptococcus pneumoniae CGSP14 6216356 YP_001836871.1 CDS glpK NC_010582.1 2152893 2154401 R Converts glycerol and ADP to glycerol-3-phosphate and ADP; glycerol kinase complement(2152893..2154401) Streptococcus pneumoniae CGSP14 6217304 YP_001836872.1 CDS SPCG_2155 NC_010582.1 2154560 2155987 R hypothetical protein complement(2154560..2155987) Streptococcus pneumoniae CGSP14 6216963 YP_001836873.1 CDS hslO NC_010582.1 2156152 2157024 D becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers; Hsp33-like chaperonin 2156152..2157024 Streptococcus pneumoniae CGSP14 6218041 YP_001836874.1 CDS SPCG_2157 NC_010582.1 2156981 2157991 D NifR3 family TIM-barrel protein 2156981..2157991 Streptococcus pneumoniae CGSP14 6217539 YP_001836875.1 CDS pspC NC_010582.1 2158221 2160383 R choline binding protein A complement(2158221..2160383) Streptococcus pneumoniae CGSP14 6217403 YP_001836876.1 CDS SPCG_2159 NC_010582.1 2160462 2160989 R hypothetical protein complement(2160462..2160989) Streptococcus pneumoniae CGSP14 6216574 YP_001836877.1 CDS SPCG_2160 NC_010582.1 2161084 2162415 R sensor histidine kinase complement(2161084..2162415) Streptococcus pneumoniae CGSP14 6216704 YP_001836878.1 CDS SPCG_2161 NC_010582.1 2162412 2163065 R DNA-binding response regulator complement(2162412..2163065) Streptococcus pneumoniae CGSP14 6217291 YP_001836879.1 CDS SPCG_2162 NC_010582.1 2163707 2166139 R ATP-dependent Clp protease, ATP-binding subunit complement(2163707..2166139) Streptococcus pneumoniae CGSP14 6217220 YP_001836880.1 CDS ctsR NC_010582.1 2166141 2166662 R CtsR family transcriptional regulator complement(2166141..2166662) Streptococcus pneumoniae CGSP14 6216561 YP_001836881.1 CDS SPCG_2164 NC_010582.1 2166718 2167446 R ABC transporter ATP-binding protein complement(2166718..2167446) Streptococcus pneumoniae CGSP14 6216862 YP_001836882.1 CDS SPCG_2165 NC_010582.1 2167446 2168453 R ABC transporter substrate-binding protein complement(2167446..2168453) Streptococcus pneumoniae CGSP14 6216856 YP_001836883.1 CDS SPCG_2166 NC_010582.1 2168492 2169241 R ABC transporter permease complement(2168492..2169241) Streptococcus pneumoniae CGSP14 6217086 YP_001836884.1 CDS SPCG_2167 NC_010582.1 2169213 2169503 R hypothetical protein complement(2169213..2169503) Streptococcus pneumoniae CGSP14 6217906 YP_001836885.1 CDS cbpD NC_010582.1 2169759 2171105 R choline binding protein D complement(2169759..2171105) Streptococcus pneumoniae CGSP14 6217546 YP_001836886.1 CDS SPCG_2169 NC_010582.1 2171194 2171460 R hypothetical protein complement(2171194..2171460) Streptococcus pneumoniae CGSP14 6217678 YP_001836887.1 CDS dnaC NC_010582.1 2171462 2172814 R unwinds double stranded DNA; replicative DNA helicase complement(2171462..2172814) Streptococcus pneumoniae CGSP14 6216638 YP_001836888.1 CDS rplI NC_010582.1 2172858 2173310 R in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 complement(2172858..2173310) Streptococcus pneumoniae CGSP14 6217234 YP_001836889.1 CDS SPCG_2172 NC_010582.1 2173307 2175280 R DHH subfamily 1 protein complement(2173307..2175280) Streptococcus pneumoniae CGSP14 6217986 YP_001836890.1 CDS SPCG_2173 NC_010582.1 2175416 2175964 R ribosomal subunit interface protein complement(2175416..2175964) Streptococcus pneumoniae CGSP14 6217408 YP_001836891.1 CDS comFC NC_010582.1 2176044 2176706 R competence protein ComF complement(2176044..2176706) Streptococcus pneumoniae CGSP14 6218048 YP_001836892.1 CDS comFA NC_010582.1 2176703 2178001 R helicase complement(2176703..2178001) Streptococcus pneumoniae CGSP14 6217509 YP_001836893.1 CDS SPCG_2176 NC_010582.1 2178057 2178692 D hypothetical protein 2178057..2178692 Streptococcus pneumoniae CGSP14 6218213 YP_001836894.1 CDS cycK NC_010582.1 2178977 2179897 D cysteine synthase 2178977..2179897 Streptococcus pneumoniae CGSP14 6218245 YP_001836895.1 CDS SPCG_2178 NC_010582.1 2180094 2180492 R transposase complement(2180094..2180492) Streptococcus pneumoniae CGSP14 6217032 YP_001836896.1 CDS SPCG_2179 NC_010582.1 2180932 2181255 R IS66 family Orf2 complement(2180932..2181255) Streptococcus pneumoniae CGSP14 6217464 YP_001836897.1 CDS tsf NC_010582.1 2181501 2182541 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(2181501..2182541) Streptococcus pneumoniae CGSP14 6218252 YP_001836898.2 CDS rpsB NC_010582.1 2182620 2183399 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(2182620..2183399) Streptococcus pneumoniae CGSP14 6217821 YP_001836899.1 CDS SPCG_2182 NC_010582.1 2183622 2184800 R secreted 45 kd protein complement(2183622..2184800) Streptococcus pneumoniae CGSP14 6217667 YP_001836900.1 CDS mreD NC_010582.1 2184894 2185388 R rod shpae-determining protein MreD complement(2184894..2185388) Streptococcus pneumoniae CGSP14 6217605 YP_001836901.1 CDS mreC NC_010582.1 2185388 2186206 R in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC complement(2185388..2186206) Streptococcus pneumoniae CGSP14 6217977 YP_001836902.1 CDS SPCG_2185 NC_010582.1 2186265 2187059 R hypothetical protein complement(2186265..2187059) Streptococcus pneumoniae CGSP14 6217511 YP_001836903.1 CDS cbiO NC_010582.1 2187052 2187891 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2187052..2187891) Streptococcus pneumoniae CGSP14 6217261 YP_001836904.1 CDS cbiO NC_010582.1 2187876 2188703 R with CbiNQ forms the ABC transporter for cobalt import; Streptococcus has two adjacent copies of this gene; cobalt transporter ATP-binding subunit complement(2187876..2188703) Streptococcus pneumoniae CGSP14 6217302 YP_001836905.1 CDS SPCG_2188 NC_010582.1 2188700 2189245 R CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(2188700..2189245) Streptococcus pneumoniae CGSP14 6217458 YP_001836906.1 CDS SPCG_2189 NC_010582.1 2189256 2190086 R hypothetical protein complement(2189256..2190086) Streptococcus pneumoniae CGSP14 6217982 YP_001836907.1 CDS SPCG_2190 NC_010582.1 2190119 2191402 R M16 family peptidase complement(2190119..2191402) Streptococcus pneumoniae CGSP14 6217568 YP_001836908.1 CDS SPCG_2191 NC_010582.1 2191399 2192649 R hypothetical protein complement(2191399..2192649) Streptococcus pneumoniae CGSP14 6217582 YP_001836909.1 CDS SPCG_2192 NC_010582.1 2192808 2193176 D hypothetical protein 2192808..2193176 Streptococcus pneumoniae CGSP14 6217940 YP_001836910.1 CDS recF NC_010582.1 2193179 2194276 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 2193179..2194276 Streptococcus pneumoniae CGSP14 6217553 YP_001836911.1 CDS imdH NC_010582.1 2194327 2195805 R catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; inosine 5'-monophosphate dehydrogenase complement(2194327..2195805) Streptococcus pneumoniae CGSP14 6216353 YP_001836912.1 CDS trpS NC_010582.1 2195957 2196982 R catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; tryptophanyl-tRNA synthetase II complement(2195957..2196982) Streptococcus pneumoniae CGSP14 6218219 YP_001836913.1 CDS SPCG_2196 NC_010582.1 2197188 2198810 D ABC transporter ATP-binding protein 2197188..2198810 Streptococcus pneumoniae CGSP14 6217782 YP_001836914.1 CDS SPCG_2197 NC_010582.1 2198872 2201424 D ABC transporter permease 2198872..2201424 Streptococcus pneumoniae CGSP14 6218069 YP_001836915.1 CDS SPCG_2198 NC_010582.1 2201867 2202205 R hypothetical protein complement(2201867..2202205) Streptococcus pneumoniae CGSP14 6217083 YP_001836916.1 CDS SPCG_2199 NC_010582.1 2202290 2203057 R hypothetical protein complement(2202290..2203057) Streptococcus pneumoniae CGSP14 6217065 YP_001836917.1 CDS SPCG_2200 NC_010582.1 2203236 2203778 D TetR family transcriptional regulator 2203236..2203778 Streptococcus pneumoniae CGSP14 6217221 YP_001836918.1 CDS comE NC_010582.1 2204021 2204773 R response regulator ComE complement(2204021..2204773) Streptococcus pneumoniae CGSP14 6217951 YP_001836919.1 CDS comD NC_010582.1 2204770 2206095 R sensor histidine kinase ComD complement(2204770..2206095) Streptococcus pneumoniae CGSP14 6218300 YP_001836920.1 CDS comC NC_010582.1 2206116 2206241 R competence stimulating peptide 2 complement(2206116..2206241) Streptococcus pneumoniae CGSP14 6217427 YP_001836921.1 CDS SPCG_2204 NC_010582.1 2206523 2207002 R SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA; rRNA large subunit methyltransferase complement(2206523..2207002) Streptococcus pneumoniae CGSP14 6217067 YP_001836922.1 CDS sphtra NC_010582.1 2207173 2208366 D serine protease 2207173..2208366 Streptococcus pneumoniae CGSP14 6217643 YP_001836923.1 CDS spo0J NC_010582.1 2208424 2209182 D spoJ protein 2208424..2209182 Streptococcus pneumoniae CGSP14 6217478 SPCG_t01 tRNA SPCG_t01 NC_010582.1 15023 15094 D tRNA-Glu 15023..15094 Streptococcus pneumoniae CGSP14 6216795 SPCG_t02 tRNA SPCG_t02 NC_010582.1 16942 17014 D tRNA-Ala 16942..17014 Streptococcus pneumoniae CGSP14 6217580 SPCG_t03 tRNA SPCG_t03 NC_010582.1 20233 20306 D tRNA-Asn 20233..20306 Streptococcus pneumoniae CGSP14 6217651 SPCG_t04 tRNA SPCG_t04 NC_010582.1 790859 790939 D tRNA-Tyr 790859..790939 Streptococcus pneumoniae CGSP14 6216466 SPCG_t05 tRNA SPCG_t05 NC_010582.1 790949 791020 D tRNA-Gln 790949..791020 Streptococcus pneumoniae CGSP14 6216552 SPCG_t06 tRNA SPCG_t06 NC_010582.1 807635 807722 R tRNA-Ser complement(807635..807722) Streptococcus pneumoniae CGSP14 6217927 SPCG_t07 tRNA SPCG_t07 NC_010582.1 967020 967092 D tRNA-Thr 967020..967092 Streptococcus pneumoniae CGSP14 6218493 SPCG_t08 tRNA SPCG_t08 NC_010582.1 1023860 1023931 D tRNA-Arg 1023860..1023931 Streptococcus pneumoniae CGSP14 6217789 SPCG_t09 tRNA SPCG_t09 NC_010582.1 1248104 1248175 R tRNA-Arg complement(1248104..1248175) Streptococcus pneumoniae CGSP14 6216428 SPCG_t10 tRNA SPCG_t10 NC_010582.1 1535520 1535605 R tRNA-Leu complement(1535520..1535605) Streptococcus pneumoniae CGSP14 6217680 SPCG_t11 tRNA SPCG_t11 NC_010582.1 1756628 1756700 D tRNA-Lys 1756628..1756700 Streptococcus pneumoniae CGSP14 6218033 SPCG_t12 tRNA SPCG_t12 NC_010582.1 1859561 1859648 R tRNA-Ser complement(1859561..1859648) Streptococcus pneumoniae CGSP14 6216464 SPCG_t13 tRNA SPCG_t13 NC_010582.1 1859655 1859728 R tRNA-Ile complement(1859655..1859728) Streptococcus pneumoniae CGSP14 6218191 SPCG_t14 tRNA SPCG_t14 NC_010582.1 1859764 1859834 R tRNA-Gly complement(1859764..1859834) Streptococcus pneumoniae CGSP14 6218352 SPCG_t15 tRNA SPCG_t15 NC_010582.1 1859854 1859926 R tRNA-Phe complement(1859854..1859926) Streptococcus pneumoniae CGSP14 6217793 SPCG_t16 tRNA SPCG_t16 NC_010582.1 1859930 1860003 R tRNA-Met complement(1859930..1860003) Streptococcus pneumoniae CGSP14 6218014 SPCG_t17 tRNA SPCG_t17 NC_010582.1 1860014 1860103 R tRNA-Ser complement(1860014..1860103) Streptococcus pneumoniae CGSP14 6218032 SPCG_t18 tRNA SPCG_t18 NC_010582.1 1860114 1860187 R tRNA-Met complement(1860114..1860187) Streptococcus pneumoniae CGSP14 6216998 SPCG_t19 tRNA SPCG_t19 NC_010582.1 1860201 1860274 R tRNA-Met complement(1860201..1860274) Streptococcus pneumoniae CGSP14 6216776 SPCG_t20 tRNA SPCG_t20 NC_010582.1 1860280 1860353 R tRNA-Pro complement(1860280..1860353) Streptococcus pneumoniae CGSP14 6216982 SPCG_t21 tRNA SPCG_t21 NC_010582.1 1860369 1860442 R tRNA-Arg complement(1860369..1860442) Streptococcus pneumoniae CGSP14 6218117 SPCG_t22 tRNA SPCG_t22 NC_010582.1 1860452 1860537 R tRNA-Leu complement(1860452..1860537) Streptococcus pneumoniae CGSP14 6216485 SPCG_t23 tRNA SPCG_t23 NC_010582.1 1860545 1860616 R tRNA-Gly complement(1860545..1860616) Streptococcus pneumoniae CGSP14 6217894 SPCG_t24 tRNA SPCG_t24 NC_010582.1 1860639 1860711 R tRNA-Thr complement(1860639..1860711) Streptococcus pneumoniae CGSP14 6216730 SPCG_t25 tRNA SPCG_t25 NC_010582.1 1860730 1860811 R tRNA-Leu complement(1860730..1860811) Streptococcus pneumoniae CGSP14 6216509 SPCG_t26 tRNA SPCG_t26 NC_010582.1 1860817 1860889 R tRNA-Lys complement(1860817..1860889) Streptococcus pneumoniae CGSP14 6216500 SPCG_t27 tRNA SPCG_t27 NC_010582.1 1860914 1860986 R tRNA-Asp complement(1860914..1860986) Streptococcus pneumoniae CGSP14 6217513 SPCG_t28 tRNA SPCG_t28 NC_010582.1 1860989 1861061 R tRNA-Val complement(1860989..1861061) Streptococcus pneumoniae CGSP14 6216602 SPCG_t29 tRNA SPCG_t29 NC_010582.1 1864284 1864356 R tRNA-Ala complement(1864284..1864356) Streptococcus pneumoniae CGSP14 6217286 SPCG_t30 tRNA SPCG_t30 NC_010582.1 1866205 1866276 R tRNA-Glu complement(1866205..1866276) Streptococcus pneumoniae CGSP14 6216331 SPCG_t31 tRNA SPCG_t31 NC_010582.1 1913692 1913762 D tRNA-Cys 1913692..1913762 Streptococcus pneumoniae CGSP14 6218135 SPCG_t32 tRNA SPCG_t32 NC_010582.1 1951482 1951555 R tRNA-Pro complement(1951482..1951555) Streptococcus pneumoniae CGSP14 6218087 SPCG_t33 tRNA SPCG_t33 NC_010582.1 1951571 1951644 R tRNA-Arg complement(1951571..1951644) Streptococcus pneumoniae CGSP14 6217842 SPCG_t34 tRNA SPCG_t34 NC_010582.1 1951654 1951739 R tRNA-Leu complement(1951654..1951739) Streptococcus pneumoniae CGSP14 6217630 SPCG_t35 tRNA SPCG_t35 NC_010582.1 1951747 1951818 R tRNA-Gly complement(1951747..1951818) Streptococcus pneumoniae CGSP14 6218012 SPCG_t36 tRNA SPCG_t36 NC_010582.1 1951841 1951913 R tRNA-Thr complement(1951841..1951913) Streptococcus pneumoniae CGSP14 6217794 SPCG_t37 tRNA SPCG_t37 NC_010582.1 1951932 1952013 R tRNA-Leu complement(1951932..1952013) Streptococcus pneumoniae CGSP14 6218066 SPCG_t38 tRNA SPCG_t38 NC_010582.1 1952019 1952091 R tRNA-Lys complement(1952019..1952091) Streptococcus pneumoniae CGSP14 6217781 SPCG_t39 tRNA SPCG_t39 NC_010582.1 1952116 1952188 R tRNA-Asp complement(1952116..1952188) Streptococcus pneumoniae CGSP14 6216826 SPCG_t40 tRNA SPCG_t40 NC_010582.1 1952191 1952263 R tRNA-Val complement(1952191..1952263) Streptococcus pneumoniae CGSP14 6217803 SPCG_t41 tRNA SPCG_t41 NC_010582.1 1955487 1955559 R tRNA-Ala complement(1955487..1955559) Streptococcus pneumoniae CGSP14 6218253 SPCG_t42 tRNA SPCG_t42 NC_010582.1 1957407 1957478 R tRNA-Glu complement(1957407..1957478) Streptococcus pneumoniae CGSP14 6218194 SPCG_t43 tRNA SPCG_t43 NC_010582.1 2016536 2016619 R tRNA-Leu complement(2016536..2016619) Streptococcus pneumoniae CGSP14 6218332 SPCG_t44 tRNA SPCG_t44 NC_010582.1 2016629 2016700 R tRNA-Gln complement(2016629..2016700) Streptococcus pneumoniae CGSP14 6217410 SPCG_t45 tRNA SPCG_t45 NC_010582.1 2016712 2016783 R tRNA-His complement(2016712..2016783) Streptococcus pneumoniae CGSP14 6218119 SPCG_t46 tRNA SPCG_t46 NC_010582.1 2016798 2016868 R tRNA-Trp complement(2016798..2016868) Streptococcus pneumoniae CGSP14 6217701 SPCG_t47 tRNA SPCG_t47 NC_010582.1 2016873 2016953 R tRNA-Tyr complement(2016873..2016953) Streptococcus pneumoniae CGSP14 6218193 SPCG_t48 tRNA SPCG_t48 NC_010582.1 2016966 2017038 R tRNA-Phe complement(2016966..2017038) Streptococcus pneumoniae CGSP14 6217088 SPCG_t49 tRNA SPCG_t49 NC_010582.1 2017042 2017115 R tRNA-Met complement(2017042..2017115) Streptococcus pneumoniae CGSP14 6218197 SPCG_t50 tRNA SPCG_t50 NC_010582.1 2017126 2017215 R tRNA-Ser complement(2017126..2017215) Streptococcus pneumoniae CGSP14 6218089 SPCG_t51 tRNA SPCG_t51 NC_010582.1 2017298 2017371 R tRNA-Ile complement(2017298..2017371) Streptococcus pneumoniae CGSP14 6217851 SPCG_t52 tRNA SPCG_t52 NC_010582.1 2017406 2017476 R tRNA-Gly complement(2017406..2017476) Streptococcus pneumoniae CGSP14 6216901 SPCG_t53 tRNA SPCG_t53 NC_010582.1 2017482 2017554 R tRNA-Val complement(2017482..2017554) Streptococcus pneumoniae CGSP14 6218039 SPCG_t54 tRNA SPCG_t54 NC_010582.1 2020777 2020849 R tRNA-Ala complement(2020777..2020849) Streptococcus pneumoniae CGSP14 6217883 SPCG_t55 tRNA SPCG_t55 NC_010582.1 2022698 2022769 R tRNA-Glu complement(2022698..2022769) Streptococcus pneumoniae CGSP14 6218290 SPCG_t56 tRNA SPCG_t56 NC_010582.1 2203819 2203892 R tRNA-Asn complement(2203819..2203892) Streptococcus pneumoniae CGSP14 6216622 SPCG_t57 tRNA SPCG_t57 NC_010582.1 2203898 2203969 R tRNA-Glu complement(2203898..2203969) Streptococcus pneumoniae CGSP14 6216761 SPCG_t58 tRNA SPCG_t58 NC_010582.1 2206406 2206479 R tRNA-Arg complement(2206406..2206479) Streptococcus pneumoniae CGSP14 6217260 SPCG_s01 rRNA SPCG_s01 NC_010582.1 15392 16803 D 16S ribosomal RNA 15392..16803 Streptococcus pneumoniae CGSP14 6217416 SPCG_s02 rRNA SPCG_s02 NC_010582.1 17139 20035 D 23S ribosomal RNA 17139..20035 Streptococcus pneumoniae CGSP14 6217489 SPCG_s03 rRNA SPCG_s03 NC_010582.1 20105 20252 D 5S ribosomal RNA 20105..20252 Streptococcus pneumoniae CGSP14 6217490 SPCG_s04 rRNA SPCG_s04 NC_010582.1 1861062 1861188 R 5S ribosomal RNA complement(1861062..1861188) Streptococcus pneumoniae CGSP14 6216449 SPCG_s05 rRNA SPCG_s05 NC_010582.1 1861258 1864159 R 23S ribosomal RNA complement(1861258..1864159) Streptococcus pneumoniae CGSP14 6216662 SPCG_s06 rRNA SPCG_s06 NC_010582.1 1864495 1865907 R 16S ribosomal RNA complement(1864495..1865907) Streptococcus pneumoniae CGSP14 6217981 SPCG_s07 rRNA SPCG_s07 NC_010582.1 1952264 1952390 R 5S ribosomal RNA complement(1952264..1952390) Streptococcus pneumoniae CGSP14 6217742 SPCG_s08 rRNA SPCG_s08 NC_010582.1 1952460 1955362 R 23S ribosomal RNA complement(1952460..1955362) Streptococcus pneumoniae CGSP14 6218244 SPCG_s09 rRNA SPCG_s09 NC_010582.1 1955698 1957109 R 16S ribosomal RNA complement(1955698..1957109) Streptococcus pneumoniae CGSP14 6218070 SPCG_s10 rRNA SPCG_s10 NC_010582.1 2017555 2017681 R 5S ribosomal RNA complement(2017555..2017681) Streptococcus pneumoniae CGSP14 6218131 SPCG_s11 rRNA SPCG_s11 NC_010582.1 2017751 2020652 R 23S ribosomal RNA complement(2017751..2020652) Streptococcus pneumoniae CGSP14 6217947 SPCG_s12 rRNA SPCG_s12 NC_010582.1 2020988 2022400 R 16S ribosomal RNA complement(2020988..2022400) Streptococcus pneumoniae CGSP14 6217987