-- dump date 20140620_084344 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 574093000001 SEQ_END SEQ_END NC_014494.1 2130580 2130580 DR NC_014494.1; contig end 2130580..2130580 Streptococcus pneumoniae AP200 YP_003875603.1 CDS SPAP_0001 NC_014494.1 197 1558 D Operon 1 Gene 1 COG0593 ATPase involved in DNA replication initiation; DNA replication initiation ATPase 197..1558 Streptococcus pneumoniae AP200 9728302 YP_003875604.1 CDS SPAP_0002 NC_014494.1 1717 2853 D Operon 1 Gene 2 COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase sliding clamp subunit 1717..2853 Streptococcus pneumoniae AP200 9726019 YP_003875605.1 CDS SPAP_0003 NC_014494.1 2918 3112 D Operon 2 Gene 1 COG4481 Uncharacterized protein conserved in bacteria; hypothetical protein 2918..3112 Streptococcus pneumoniae AP200 9726020 YP_003875606.1 CDS SPAP_0004 NC_014494.1 3196 4311 D Operon 3 Gene 1 COG0012 Predicted GTPase, probable translation factor; putative GTPase, probable translation factor 3196..4311 Streptococcus pneumoniae AP200 9726021 YP_003875607.1 CDS SPAP_0005 NC_014494.1 4382 4951 D Operon 3 Gene 2 COG0193 Peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 4382..4951 Streptococcus pneumoniae AP200 9726022 YP_003875608.1 CDS SPAP_0006 NC_014494.1 4952 8461 D Operon 3 Gene 3 COG1197 Transcription-repair coupling factor (superfamily II helicase); transcription-repair coupling factor 4952..8461 Streptococcus pneumoniae AP200 9726023 YP_003875609.1 CDS SPAP_0007 NC_014494.1 8519 8785 D Operon 3 Gene 4 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog); ribosome-associated heat shock protein 8519..8785 Streptococcus pneumoniae AP200 9726024 YP_003875610.1 CDS SPAP_0008 NC_014494.1 8778 9146 D Operon 3 Gene 5 COG2919 Septum formation initiator; septum formation initiator 8778..9146 Streptococcus pneumoniae AP200 9726025 YP_003875611.1 CDS SPAP_0009 NC_014494.1 9151 9273 D Operon 3 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 9151..9273 Streptococcus pneumoniae AP200 9726026 YP_003875612.1 CDS SPAP_0010 NC_014494.1 9266 10534 D Operon 3 Gene 7 COG2367 Beta-lactamase class A; beta-lactamase class A 9266..10534 Streptococcus pneumoniae AP200 9726027 YP_003875613.1 CDS SPAP_0011 NC_014494.1 10531 11808 D Operon 3 Gene 8 COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; putative ATPase 10531..11808 Streptococcus pneumoniae AP200 9726028 YP_003875614.1 CDS SPAP_0012 NC_014494.1 11812 12354 D Operon 3 Gene 9 COG0634 Hypoxanthine-guanine phosphoribosyltransferase; hypoxanthine-guanine phosphoribosyltransferase 11812..12354 Streptococcus pneumoniae AP200 9726029 YP_003875615.1 CDS SPAP_0013 NC_014494.1 12370 14328 D Operon 3 Gene 10 COG0465 ATP-dependent Zn proteases; ATP-dependent Zn protease 12370..14328 Streptococcus pneumoniae AP200 9726030 YP_003875616.1 CDS SPAP_0014 NC_014494.1 14450 14713 D Operon 4 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 14450..14713 Streptococcus pneumoniae AP200 9726031 YP_003875617.1 CDS SPAP_0021 NC_014494.1 20410 20727 R Operon 5 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein complement(20410..20727) Streptococcus pneumoniae AP200 9726038 YP_003875618.1 CDS SPAP_0022 NC_014494.1 20951 21157 R Operon 6 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein complement(20951..21157) Streptococcus pneumoniae AP200 9726039 YP_003875619.1 CDS SPAP_0023 NC_014494.1 21473 21709 D Operon 7 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 21473..21709 Streptococcus pneumoniae AP200 9726040 YP_003875620.1 CDS SPAP_0024 NC_014494.1 21898 23226 D Operon 7 Gene 2 COG0104 Adenylosuccinate synthase; adenylosuccinate synthase 21898..23226 Streptococcus pneumoniae AP200 9726041 YP_003875621.1 CDS SPAP_0025 NC_014494.1 23468 24616 R Operon 8 Gene 1 COG0582 Integrase; integrase complement(23468..24616) Streptococcus pneumoniae AP200 9726042 YP_003875622.1 CDS SPAP_0026 NC_014494.1 24787 25587 R Operon 9 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(24787..25587) Streptococcus pneumoniae AP200 9726043 YP_003875623.1 CDS SPAP_0027 NC_014494.1 25714 26469 R Operon 9 Gene 2 COG2932 Predicted transcriptional regulator; putative transcriptional regulator complement(25714..26469) Streptococcus pneumoniae AP200 9726044 YP_003875624.1 CDS SPAP_0028 NC_014494.1 26643 26849 D Operon 10 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 26643..26849 Streptococcus pneumoniae AP200 9726045 YP_003875625.1 CDS SPAP_0029 NC_014494.1 26871 27032 D hypothetical protein 26871..27032 Streptococcus pneumoniae AP200 9726046 YP_003875626.1 CDS SPAP_0030 NC_014494.1 27066 27194 D Operon 11 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 27066..27194 Streptococcus pneumoniae AP200 9726047 YP_003875627.1 CDS SPAP_0031 NC_014494.1 27157 27834 R Operon 12 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(27157..27834) Streptococcus pneumoniae AP200 9726048 YP_003875628.1 CDS SPAP_0032 NC_014494.1 27889 28602 D Operon 13 Gene 1 COG3617 Prophage antirepressor; prophage antirepressor 27889..28602 Streptococcus pneumoniae AP200 9726049 YP_003875629.1 CDS SPAP_0033 NC_014494.1 28615 28872 D Operon 13 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 28615..28872 Streptococcus pneumoniae AP200 9726050 YP_003875630.1 CDS SPAP_0034 NC_014494.1 28958 29278 D Operon 14 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 28958..29278 Streptococcus pneumoniae AP200 9726051 YP_003875631.1 CDS SPAP_0035 NC_014494.1 29294 29587 D Operon 14 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 29294..29587 Streptococcus pneumoniae AP200 9726052 YP_003875632.1 CDS SPAP_0036 NC_014494.1 29571 30407 D similar to gp19 of Streptococcus mitis phage SM1; hypothetical protein 29571..30407 Streptococcus pneumoniae AP200 9726053 YP_003875633.1 CDS SPAP_0037 NC_014494.1 30395 30553 D Operon 14 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 30395..30553 Streptococcus pneumoniae AP200 9726054 YP_003875634.1 CDS SPAP_0038 NC_014494.1 30547 31317 D Operon 14 Gene 5 COG1484 DNA replication protein; DNA replication protein 30547..31317 Streptococcus pneumoniae AP200 9726055 YP_003875635.1 CDS SPAP_0039 NC_014494.1 31332 31526 D Operon 14 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 31332..31526 Streptococcus pneumoniae AP200 9726056 YP_003875636.1 CDS SPAP_0040 NC_014494.1 31526 31753 D Operon 14 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 31526..31753 Streptococcus pneumoniae AP200 9726057 YP_003875637.1 CDS SPAP_0041 NC_014494.1 31746 31850 D Operon 14 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 31746..31850 Streptococcus pneumoniae AP200 9726058 YP_003875638.1 CDS SPAP_0042 NC_014494.1 31938 32147 D Operon 14 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 31938..32147 Streptococcus pneumoniae AP200 9726059 YP_003875639.1 CDS SPAP_0043 NC_014494.1 32119 32436 D Operon 14 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 32119..32436 Streptococcus pneumoniae AP200 9726060 YP_003875640.1 CDS SPAP_0044 NC_014494.1 32438 33133 D Operon 14 Gene 11 Putative gene predicted by FgenesB; hypothetical protein 32438..33133 Streptococcus pneumoniae AP200 9726061 YP_003875641.1 CDS SPAP_0045 NC_014494.1 33371 33724 D Operon 15 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 33371..33724 Streptococcus pneumoniae AP200 9726062 YP_003875642.1 CDS SPAP_0046 NC_014494.1 33706 34170 D Operon 15 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 33706..34170 Streptococcus pneumoniae AP200 9726063 YP_003875643.1 CDS SPAP_0047 NC_014494.1 34279 34821 D Operon 16 Gene 1 COG0582 Integrase; integrase 34279..34821 Streptococcus pneumoniae AP200 9726064 YP_003875644.1 CDS SPAP_0048 NC_014494.1 35027 35254 D hypothetical protein 35027..35254 Streptococcus pneumoniae AP200 9726065 YP_003875645.1 CDS SPAP_0049 NC_014494.1 35251 35568 D similar to SAG1857 prophage LambdaSa2; HNH endonuclease family protein 35251..35568 Streptococcus pneumoniae AP200 9726066 YP_003875646.1 CDS SPAP_0050 NC_014494.1 35705 36190 D Operon 18 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 35705..36190 Streptococcus pneumoniae AP200 9726067 YP_003875647.1 CDS SPAP_0051 NC_014494.1 36183 37895 D Operon 18 Gene 2 COG4626 Phage terminase-like protein, large subunit; phage terminase-like protein large subunit 36183..37895 Streptococcus pneumoniae AP200 9726068 YP_003875648.1 CDS SPAP_0052 NC_014494.1 37904 39046 D similar to SAG1854 prophage LambdaSa2; hypothetical protein 37904..39046 Streptococcus pneumoniae AP200 9726069 YP_003875649.1 CDS SPAP_0053 NC_014494.1 39093 39635 D Operon 19 Gene 2 COG3740 Phage head maturation protease; phage head maturation protease 39093..39635 Streptococcus pneumoniae AP200 9726070 YP_003875650.1 CDS SPAP_0054 NC_014494.1 39650 40903 D Operon 19 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 39650..40903 Streptococcus pneumoniae AP200 9726071 YP_003875651.1 CDS SPAP_0055 NC_014494.1 40929 41264 D Operon 19 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 40929..41264 Streptococcus pneumoniae AP200 9726072 YP_003875652.1 CDS SPAP_0056 NC_014494.1 41261 41566 D Operon 19 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 41261..41566 Streptococcus pneumoniae AP200 9726073 YP_003875653.1 CDS SPAP_0057 NC_014494.1 41566 41913 D Operon 19 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 41566..41913 Streptococcus pneumoniae AP200 9726074 YP_003875654.1 CDS SPAP_0058 NC_014494.1 41900 42244 D Operon 19 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 41900..42244 Streptococcus pneumoniae AP200 9726075 YP_003875655.1 CDS SPAP_0059 NC_014494.1 42258 42926 D Operon 19 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 42258..42926 Streptococcus pneumoniae AP200 9726076 YP_003875656.1 CDS SPAP_0060 NC_014494.1 42928 43404 D Operon 19 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 42928..43404 Streptococcus pneumoniae AP200 9726077 YP_003875657.1 CDS SPAP_0061 NC_014494.1 43443 43571 D Operon 19 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 43443..43571 Streptococcus pneumoniae AP200 9726078 YP_003875658.1 CDS SPAP_0062 NC_014494.1 43591 46329 D Operon 19 Gene 11 COG5280 Phage-related minor tail protein; phage-related minor tail protein 43591..46329 Streptococcus pneumoniae AP200 9726079 YP_003875659.1 CDS SPAP_0063 NC_014494.1 46326 47048 D Operon 19 Gene 12 Putative gene predicted by FgenesB; hypothetical protein 46326..47048 Streptococcus pneumoniae AP200 9726080 YP_003875660.1 CDS SPAP_0064 NC_014494.1 47049 56156 D Operon 19 Gene 13 COG4926 Phage-related protein; PblB, putative 47049..56156 Streptococcus pneumoniae AP200 9726081 YP_003875661.1 CDS SPAP_0065 NC_014494.1 56250 56453 D Operon 19 Gene 15 Putative gene predicted by FgenesB; hypothetical protein 56250..56453 Streptococcus pneumoniae AP200 9726082 YP_003875662.1 CDS SPAP_0066 NC_014494.1 56456 56806 D Operon 19 Gene 16 Putative gene predicted by FgenesB; hypothetical protein 56456..56806 Streptococcus pneumoniae AP200 9726083 YP_003875663.1 CDS SPAP_0067 NC_014494.1 56816 57232 D Operon 19 Gene 17 Putative gene predicted by FgenesB; hypothetical protein 56816..57232 Streptococcus pneumoniae AP200 9726084 YP_003875664.1 CDS SPAP_0068 NC_014494.1 57236 57568 D Operon 19 Gene 18 Putative gene predicted by FgenesB; hypothetical protein 57236..57568 Streptococcus pneumoniae AP200 9726085 YP_003875665.1 CDS SPAP_0069 NC_014494.1 57572 58528 D Operon 19 Gene 19 COG5263 FOG: autolysin; autolysin 57572..58528 Streptococcus pneumoniae AP200 9726086 YP_003875666.1 CDS SPAP_0070 NC_014494.1 58666 58845 R Operon 20 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(58666..58845) Streptococcus pneumoniae AP200 9726087 YP_003875667.1 CDS SPAP_0071 NC_014494.1 58987 59142 R hypothetical protein complement(58987..59142) Streptococcus pneumoniae AP200 9726088 YP_003875668.1 CDS SPAP_0072 NC_014494.1 59416 59883 D Operon 21 Gene 1 COG0590 Cytosine/adenosine deaminases; cytosine/adenosine deaminase 59416..59883 Streptococcus pneumoniae AP200 9726089 YP_003875669.1 CDS SPAP_0073 NC_014494.1 60069 60512 D Operon 22 Gene 1 COG0756 dUTPase; dUTPase 60069..60512 Streptococcus pneumoniae AP200 9726090 YP_003875670.1 CDS SPAP_0074 NC_014494.1 60514 61029 D Operon 22 Gene 2 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 60514..61029 Streptococcus pneumoniae AP200 9726091 YP_003875671.1 CDS SPAP_0075 NC_014494.1 61142 62404 D Operon 23 Gene 1 COG1066 Predicted ATP-dependent serine protease; putative ATP-dependent serine protease 61142..62404 Streptococcus pneumoniae AP200 9726092 YP_003875672.1 CDS SPAP_0076 NC_014494.1 62408 62974 D Operon 23 Gene 2 COG0288 Carbonic anhydrase; carbonic anhydrase 62408..62974 Streptococcus pneumoniae AP200 9726093 YP_003875673.1 CDS SPAP_0077 NC_014494.1 62999 63208 D Operon 23 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 62999..63208 Streptococcus pneumoniae AP200 9726094 YP_003875674.1 CDS SPAP_0078 NC_014494.1 63229 63813 D Operon 23 Gene 4 COG2339 Predicted membrane protein; hypothetical protein 63229..63813 Streptococcus pneumoniae AP200 9726095 YP_003875675.1 CDS SPAP_0079 NC_014494.1 63958 64926 D Operon 24 Gene 1 COG0462 Phosphoribosylpyrophosphate synthetase; phosphoribosylpyrophosphate synthetase 63958..64926 Streptococcus pneumoniae AP200 9726096 YP_003875676.1 CDS SPAP_0080 NC_014494.1 64862 65341 R Operon 25 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein complement(64862..65341) Streptococcus pneumoniae AP200 9726097 YP_003875677.1 CDS SPAP_0081 NC_014494.1 65467 65700 R Operon 26 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(65467..65700) Streptococcus pneumoniae AP200 9726098 YP_003875678.1 CDS SPAP_0082 NC_014494.1 66129 66338 R Operon 26 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(66129..66338) Streptococcus pneumoniae AP200 9726099 YP_003875679.1 CDS SPAP_0083 NC_014494.1 66594 69263 D Operon 27 Gene 1 COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; DNA polymerase I - 3'-5' exonuclease and polymerase domains 66594..69263 Streptococcus pneumoniae AP200 9726100 YP_003875680.1 CDS SPAP_0084 NC_014494.1 69348 69785 D Operon 27 Gene 2 COG1832 Predicted CoA-binding protein; putative CoA-binding protein 69348..69785 Streptococcus pneumoniae AP200 9726101 YP_003875681.1 CDS SPAP_0085 NC_014494.1 69968 70978 R Operon 28 Gene 1 COG2855 Predicted membrane protein; hypothetical protein complement(69968..70978) Streptococcus pneumoniae AP200 9726102 YP_003875682.1 CDS SPAP_0086 NC_014494.1 71127 72296 D Operon 29 Gene 1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase 71127..72296 Streptococcus pneumoniae AP200 9726103 YP_003875683.1 CDS SPAP_0087 NC_014494.1 72293 73063 D Operon 29 Gene 2 COG1381 Recombinational DNA repair protein (RecF pathway); recombinational DNA repair ATPase 72293..73063 Streptococcus pneumoniae AP200 9726104 YP_003875684.1 CDS SPAP_0088 NC_014494.1 73060 74052 D Operon 29 Gene 3 COG0416 Fatty acid/phospholipid biosynthesis enzyme; fatty acid/phospholipid biosynthesis enzyme 73060..74052 Streptococcus pneumoniae AP200 9726105 YP_003875685.1 CDS SPAP_0089 NC_014494.1 74058 74291 D Operon 29 Gene 4 COG0236 Acyl carrier protein; acyl carrier protein 74058..74291 Streptococcus pneumoniae AP200 9726106 YP_003875686.1 CDS SPAP_0090 NC_014494.1 75065 75184 D Operon 30 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 75065..75184 Streptococcus pneumoniae AP200 9726107 YP_003875687.1 CDS SPAP_0091 NC_014494.1 75778 77931 D Operon 31 Gene 1 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter 75778..77931 Streptococcus pneumoniae AP200 9726108 YP_003875688.1 CDS SPAP_0092 NC_014494.1 77944 79293 D Operon 31 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 77944..79293 Streptococcus pneumoniae AP200 9726109 YP_003875689.1 CDS SPAP_0093 NC_014494.1 79463 80170 D Operon 32 Gene 1 COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase 79463..80170 Streptococcus pneumoniae AP200 9726110 YP_003875690.1 CDS SPAP_0094 NC_014494.1 80227 83952 D Operon 32 Gene 2 COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain protein 80227..83952 Streptococcus pneumoniae AP200 9726111 YP_003875691.1 CDS SPAP_0095 NC_014494.1 84045 85487 D Operon 32 Gene 3 COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine phosphoribosylpyrophosphate amidotransferase 84045..85487 Streptococcus pneumoniae AP200 9726112 YP_003875692.1 CDS SPAP_0096 NC_014494.1 85524 86546 D Operon 32 Gene 4 protein supported gi|169632702|ref|YP_001706438.1| phosphoribosylaminoimidazole synthetase; hypothetical protein 85524..86546 Streptococcus pneumoniae AP200 9726113 YP_003875693.1 CDS SPAP_0097 NC_014494.1 86543 87088 D Operon 32 Gene 5 COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; folate-dependent phosphoribosylglycinamide formyltransferase PurN 86543..87088 Streptococcus pneumoniae AP200 9726114 YP_003875694.1 CDS SPAP_0098 NC_014494.1 87172 87681 D Operon 33 Gene 1 COG4767 Glycopeptide antibiotics resistance protein; glycopeptide antibiotics resistance protein 87172..87681 Streptococcus pneumoniae AP200 9726115 YP_003875695.1 CDS SPAP_0099 NC_014494.1 87706 89253 D Operon 33 Gene 2 COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); AICAR transformylase/IMP cyclohydrolase PurH 87706..89253 Streptococcus pneumoniae AP200 9726116 YP_003875696.1 CDS SPAP_0100 NC_014494.1 89375 90637 D Operon 33 Gene 3 COG0151 Phosphoribosylamine-glycine ligase; phosphoribosylamine-glycine ligase 89375..90637 Streptococcus pneumoniae AP200 9726117 YP_003875697.1 CDS SPAP_0101 NC_014494.1 90601 90801 R Operon 34 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(90601..90801) Streptococcus pneumoniae AP200 9726118 YP_003875698.1 CDS SPAP_0102 NC_014494.1 91040 91528 D Operon 35 Gene 1 COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; phosphoribosylcarboxyaminoimidazole mutase 91040..91528 Streptococcus pneumoniae AP200 9726119 YP_003875699.1 CDS SPAP_0103 NC_014494.1 91515 92606 D Operon 35 Gene 2 COG0026 Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase 91515..92606 Streptococcus pneumoniae AP200 9726120 YP_003875700.1 CDS SPAP_0104 NC_014494.1 92616 92843 D Operon 35 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 92616..92843 Streptococcus pneumoniae AP200 9726121 YP_003875701.1 CDS SPAP_0105 NC_014494.1 92906 94204 D Operon 35 Gene 4 COG0015 Adenylosuccinate lyase; adenylosuccinate lyase 92906..94204 Streptococcus pneumoniae AP200 9726122 YP_003875702.1 CDS SPAP_0106 NC_014494.1 94259 98218 R Operon 36 Gene 1 protein supported gi|149001861|ref|ZP_01826834.1| 30S ribosomal protein S4; hypothetical protein complement(94259..98218) Streptococcus pneumoniae AP200 9726123 YP_003875703.1 CDS SPAP_0107 NC_014494.1 98512 99255 R Operon 37 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator complement(98512..99255) Streptococcus pneumoniae AP200 9726124 YP_003875704.1 CDS SPAP_0108 NC_014494.1 99576 101363 D Operon 38 Gene 1 COG1874 Beta-galactosidase; beta-galactosidase 99576..101363 Streptococcus pneumoniae AP200 9726125 YP_003875705.1 CDS SPAP_0109 NC_014494.1 101360 101836 D Operon 38 Gene 2 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 101360..101836 Streptococcus pneumoniae AP200 9726126 YP_003875706.1 CDS SPAP_0110 NC_014494.1 101864 102769 D Operon 38 Gene 3 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 101864..102769 Streptococcus pneumoniae AP200 9726127 YP_003875707.1 CDS SPAP_0111 NC_014494.1 102756 103571 D Operon 38 Gene 4 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 102756..103571 Streptococcus pneumoniae AP200 9726128 YP_003875708.1 CDS SPAP_0112 NC_014494.1 103578 103982 D Operon 38 Gene 5 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA 103578..103982 Streptococcus pneumoniae AP200 9726129 YP_003875709.1 CDS SPAP_0113 NC_014494.1 104281 105447 D Operon 39 Gene 1 COG2222 Predicted phosphosugar isomerases; putative phosphosugar isomerase 104281..105447 Streptococcus pneumoniae AP200 9726130 YP_003875710.1 CDS SPAP_0114 NC_014494.1 105563 106600 D Operon 40 Gene 1 protein supported gi|15900011|ref|NP_344615.1| aldose 1-epimerase; hypothetical protein 105563..106600 Streptococcus pneumoniae AP200 9726131 YP_003875711.1 CDS SPAP_0115 NC_014494.1 106762 107274 D Operon 41 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 106762..107274 Streptococcus pneumoniae AP200 9726132 YP_003875712.1 CDS SPAP_0116 NC_014494.1 107295 107930 D Operon 41 Gene 2 COG5263 FOG: Choline binding protein I; choline binding protein I 107295..107930 Streptococcus pneumoniae AP200 9726133 YP_003875713.1 CDS SPAP_0117 NC_014494.1 108382 113952 D zinc metalloprotease ZmpC; hypothetical protein 108382..113952 Streptococcus pneumoniae AP200 9726134 YP_003875714.1 CDS SPAP_0118 NC_014494.1 114308 115162 D Operon 43 Gene 1 COG2514 Predicted ring-cleavage extradiol dioxygenase; putative ring-cleavage extradiol dioxygenase 114308..115162 Streptococcus pneumoniae AP200 9726135 YP_003875715.1 CDS SPAP_0119 NC_014494.1 115268 115825 D Operon 44 Gene 1 COG0110 Acetyltransferase (isoleucine patch superfamily); acetyltransferase 115268..115825 Streptococcus pneumoniae AP200 9726136 YP_003875716.1 CDS SPAP_0120 NC_014494.1 116042 116806 D Operon 45 Gene 1 COG2820 Uridine phosphorylase; Uridine phosphorylase 116042..116806 Streptococcus pneumoniae AP200 9726137 YP_003875717.1 CDS SPAP_0121 NC_014494.1 117419 118798 D Operon 46 Gene 1 COG0168 Trk-type K+ transport systems, membrane components; Trk-type K+ transport systems membrane protein 117419..118798 Streptococcus pneumoniae AP200 9726138 YP_003875718.1 CDS SPAP_0122 NC_014494.1 118812 119477 D Operon 46 Gene 2 COG0569 K+ transport systems, NAD-binding component; K+ transport systems NAD-binding component 118812..119477 Streptococcus pneumoniae AP200 9726139 YP_003875719.1 CDS SPAP_0123 NC_014494.1 119612 119815 D Operon 47 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 119612..119815 Streptococcus pneumoniae AP200 9726140 YP_003875720.1 CDS SPAP_0124 NC_014494.1 119877 120050 D Operon 47 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 119877..120050 Streptococcus pneumoniae AP200 9726141 YP_003875721.1 CDS SPAP_0125 NC_014494.1 120117 120527 D Operon 47 Gene 3 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 120117..120527 Streptococcus pneumoniae AP200 9726142 YP_003875722.1 CDS SPAP_0126 NC_014494.1 120643 122304 D cell wall surface anchor family protein; hypothetical protein 120643..122304 Streptococcus pneumoniae AP200 9726143 YP_003875723.1 CDS SPAP_0127 NC_014494.1 122471 123169 D Operon 49 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 122471..123169 Streptococcus pneumoniae AP200 9726144 YP_003875724.1 CDS SPAP_0128 NC_014494.1 123166 124218 D Operon 49 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 123166..124218 Streptococcus pneumoniae AP200 9726145 YP_003875725.1 CDS SPAP_0129 NC_014494.1 124413 125024 D Operon 50 Gene 1 protein supported gi|15900029|ref|NP_344633.1| 30S ribosomal protein S4; hypothetical protein 124413..125024 Streptococcus pneumoniae AP200 9726146 YP_003875726.1 CDS SPAP_0130 NC_014494.1 125209 125367 D transposase-like protein, IS630 125209..125367 Streptococcus pneumoniae AP200 9726147 YP_003875727.1 CDS SPAP_0131 NC_014494.1 125465 125605 R transposase-like protein, ISSpn2 complement(125465..125605) Streptococcus pneumoniae AP200 9726148 YP_003875728.1 CDS SPAP_0132 NC_014494.1 125685 125945 D Operon 53 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 125685..125945 Streptococcus pneumoniae AP200 9726149 YP_003875729.1 CDS SPAP_0133 NC_014494.1 125860 126120 D Operon 53 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 125860..126120 Streptococcus pneumoniae AP200 9726150 YP_003875730.1 CDS SPAP_0134 NC_014494.1 126439 127368 D Operon 54 Gene 1 COG4209 ABC-type polysaccharide transport system, permease component; polysaccharide ABC transporter permease 126439..127368 Streptococcus pneumoniae AP200 9726151 YP_003875731.1 CDS SPAP_0135 NC_014494.1 127382 128305 D Operon 54 Gene 2 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease 127382..128305 Streptococcus pneumoniae AP200 9726152 YP_003875732.1 CDS SPAP_0136 NC_014494.1 128409 129884 D Operon 54 Gene 3 protein supported gi|15900035|ref|NP_344639.1| ABC transporter, substrate-binding protein; hypothetical protein 128409..129884 Streptococcus pneumoniae AP200 9726153 YP_003875733.1 CDS SPAP_0137 NC_014494.1 130156 131142 D Operon 55 Gene 1 COG1054 Predicted sulfurtransferase; putative sulfurtransferase 130156..131142 Streptococcus pneumoniae AP200 9726154 YP_003875734.1 CDS SPAP_0138 NC_014494.1 131264 132115 D Operon 55 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 131264..132115 Streptococcus pneumoniae AP200 9726155 YP_003875735.1 CDS SPAP_0139 NC_014494.1 132196 133260 R Operon 56 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(132196..133260) Streptococcus pneumoniae AP200 9726156 YP_003875736.1 CDS SPAP_0140 NC_014494.1 133323 134234 R Operon 56 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(133323..134234) Streptococcus pneumoniae AP200 9726157 YP_003875737.1 CDS SPAP_0141 NC_014494.1 134227 134820 R Operon 56 Gene 3 COG4709 Predicted membrane protein; hypothetical protein complement(134227..134820) Streptococcus pneumoniae AP200 9726158 YP_003875738.1 CDS SPAP_0142 NC_014494.1 134807 135133 R Operon 56 Gene 4 COG1695 Predicted transcriptional regulators; putative transcriptional regulator complement(134807..135133) Streptococcus pneumoniae AP200 9726159 YP_003875739.1 CDS SPAP_0143 NC_014494.1 135272 136438 R Operon 57 Gene 1 COG2807 Cyanate permease; cyanate permease complement(135272..136438) Streptococcus pneumoniae AP200 9726160 YP_003875740.1 CDS SPAP_0144 NC_014494.1 136496 137656 D Operon 58 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 136496..137656 Streptococcus pneumoniae AP200 9726161 YP_003875741.1 CDS SPAP_0145 NC_014494.1 137695 139545 D Operon 58 Gene 2 COG1086 Predicted nucleoside-diphosphate sugar epimerases; putative nucleoside-diphosphate sugar epimerase 137695..139545 Streptococcus pneumoniae AP200 9726162 YP_003875742.1 CDS SPAP_0146 NC_014494.1 139805 140437 R Operon 59 Gene 1 COG0546 Predicted phosphatases; putative phosphatase complement(139805..140437) Streptococcus pneumoniae AP200 9726163 YP_003875743.1 CDS SPAP_0147 NC_014494.1 140459 141331 R Operon 59 Gene 2 COG1760 L-serine deaminase; L-serine deaminase complement(140459..141331) Streptococcus pneumoniae AP200 9726164 YP_003875744.1 CDS SPAP_0148 NC_014494.1 141340 142011 R Operon 59 Gene 3 COG1760 L-serine deaminase; L-serine deaminase complement(141340..142011) Streptococcus pneumoniae AP200 9726165 YP_003875745.1 CDS SPAP_0149 NC_014494.1 142253 142840 D Operon 60 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 142253..142840 Streptococcus pneumoniae AP200 9726166 YP_003875746.1 CDS SPAP_0150 NC_014494.1 142892 143212 R Operon 61 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(142892..143212) Streptococcus pneumoniae AP200 9726167 YP_003875747.1 CDS SPAP_0151 NC_014494.1 143420 143644 R Operon 62 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(143420..143644) Streptococcus pneumoniae AP200 9726168 YP_003875748.1 CDS SPAP_0152 NC_014494.1 143643 143930 D Operon 63 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 143643..143930 Streptococcus pneumoniae AP200 9726169 YP_003875749.1 CDS SPAP_0153 NC_014494.1 143982 146090 D Operon 63 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 143982..146090 Streptococcus pneumoniae AP200 9726170 YP_003875750.1 CDS SPAP_0154 NC_014494.1 146087 146728 D Operon 63 Gene 3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 146087..146728 Streptococcus pneumoniae AP200 9726171 YP_003875751.1 CDS SPAP_0155 NC_014494.1 146935 147741 D Operon 64 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 146935..147741 Streptococcus pneumoniae AP200 9726172 YP_003875752.1 CDS SPAP_0156 NC_014494.1 147758 148954 D Operon 64 Gene 2 COG0137 Argininosuccinate synthase; argininosuccinate synthase 147758..148954 Streptococcus pneumoniae AP200 9726173 YP_003875753.1 CDS SPAP_0157 NC_014494.1 148983 150374 D Operon 64 Gene 3 COG0165 Argininosuccinate lyase; argininosuccinate lyase 148983..150374 Streptococcus pneumoniae AP200 9726174 YP_003875754.1 CDS SPAP_0158 NC_014494.1 150561 151424 R Operon 65 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(150561..151424) Streptococcus pneumoniae AP200 9726175 YP_003875755.1 CDS SPAP_0159 NC_014494.1 151992 152228 D Operon 66 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 151992..152228 Streptococcus pneumoniae AP200 9726176 YP_003875756.1 CDS SPAP_0160 NC_014494.1 152206 152700 D Operon 66 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 152206..152700 Streptococcus pneumoniae AP200 9726177 YP_003875757.1 CDS SPAP_0161 NC_014494.1 152854 153066 D Operon 67 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 152854..153066 Streptococcus pneumoniae AP200 9726178 YP_003875758.1 CDS SPAP_0162 NC_014494.1 153440 153565 D Operon 68 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 153440..153565 Streptococcus pneumoniae AP200 9726179 YP_003875759.1 CDS SPAP_0163 NC_014494.1 153546 153791 D Operon 68 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 153546..153791 Streptococcus pneumoniae AP200 9726180 YP_003875760.1 CDS SPAP_0164 NC_014494.1 153948 155006 D Operon 69 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 153948..155006 Streptococcus pneumoniae AP200 9726181 YP_003875761.1 CDS SPAP_0165 NC_014494.1 155321 156298 D Operon 70 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 155321..156298 Streptococcus pneumoniae AP200 9726182 YP_003875762.1 CDS SPAP_0166 NC_014494.1 156675 157049 D Operon 71 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 156675..157049 Streptococcus pneumoniae AP200 9726183 YP_003875763.1 CDS SPAP_0167 NC_014494.1 157287 158159 D Operon 72 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 157287..158159 Streptococcus pneumoniae AP200 9726184 YP_003875764.1 CDS SPAP_0168 NC_014494.1 158215 158454 D Operon 72 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 158215..158454 Streptococcus pneumoniae AP200 9726185 YP_003875765.1 CDS SPAP_0169 NC_014494.1 158655 159179 D Operon 73 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 158655..159179 Streptococcus pneumoniae AP200 9726186 YP_003875766.1 CDS SPAP_0170 NC_014494.1 159658 159855 D Operon 74 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 159658..159855 Streptococcus pneumoniae AP200 9726187 YP_003875767.1 CDS SPAP_0171 NC_014494.1 160312 160551 D Operon 75 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 160312..160551 Streptococcus pneumoniae AP200 9726188 YP_003875768.1 CDS SPAP_0172 NC_014494.1 160536 160814 D Operon 75 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 160536..160814 Streptococcus pneumoniae AP200 9726189 YP_003875769.1 CDS SPAP_0173 NC_014494.1 161100 163379 D Operon 76 Gene 1 COG5263 FOG: surface protein pspA precursor; surface protein pspA precursor 161100..163379 Streptococcus pneumoniae AP200 9726190 YP_003875770.1 CDS SPAP_0174 NC_014494.1 163780 164901 D Operon 77 Gene 1 COG0482 Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain; putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase 163780..164901 Streptococcus pneumoniae AP200 9726191 YP_003875771.1 CDS SPAP_0175 NC_014494.1 165042 165497 D Operon 78 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 165042..165497 Streptococcus pneumoniae AP200 9726192 YP_003875772.1 CDS SPAP_0176 NC_014494.1 165507 167420 D Operon 78 Gene 2 COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; NAD/FAD-utilizing enzyme apparently involved in cell division 165507..167420 Streptococcus pneumoniae AP200 9726193 YP_003875773.1 CDS SPAP_0177 NC_014494.1 167615 169294 R Operon 79 Gene 1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; putative metallo-beta-lactamase superfamily hydrolase complement(167615..169294) Streptococcus pneumoniae AP200 9726194 YP_003875774.1 CDS SPAP_0178 NC_014494.1 169296 169529 R Operon 79 Gene 2 COG5503 Uncharacterized conserved small protein; hypothetical protein complement(169296..169529) Streptococcus pneumoniae AP200 9726195 YP_003875775.1 CDS SPAP_0179 NC_014494.1 169809 170132 D Operon 80 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 169809..170132 Streptococcus pneumoniae AP200 9726196 YP_003875776.1 CDS SPAP_0180 NC_014494.1 170154 170351 R Operon 81 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(170154..170351) Streptococcus pneumoniae AP200 9726197 YP_003875777.1 CDS SPAP_0181 NC_014494.1 170345 170497 R Operon 81 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(170345..170497) Streptococcus pneumoniae AP200 9726198 YP_003875778.1 CDS SPAP_0182 NC_014494.1 170499 170684 R Operon 81 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(170499..170684) Streptococcus pneumoniae AP200 9726199 YP_003875779.1 CDS SPAP_0183 NC_014494.1 170862 171545 D Operon 82 Gene 1 COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone; inactive metal-dependent protease-like protein 170862..171545 Streptococcus pneumoniae AP200 9726200 YP_003875780.1 CDS SPAP_0184 NC_014494.1 171542 171979 D Operon 82 Gene 2 protein supported gi|15902174|ref|NP_357724.1| ribosomal protein alanine acetyltransferase; hypothetical protein 171542..171979 Streptococcus pneumoniae AP200 9726201 YP_003875781.1 CDS SPAP_0185 NC_014494.1 171969 172979 D Operon 82 Gene 3 protein supported gi|229232313|ref|ZP_04356740.1| (SSU ribosomal protein S18P)-alanine acetyltransferase; hypothetical protein 171969..172979 Streptococcus pneumoniae AP200 9726202 YP_003875782.1 CDS SPAP_0186 NC_014494.1 173019 173405 R Operon 83 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(173019..173405) Streptococcus pneumoniae AP200 9726203 YP_003875783.1 CDS SPAP_0187 NC_014494.1 173396 174013 R Operon 83 Gene 2 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(173396..174013) Streptococcus pneumoniae AP200 9726204 YP_003875784.1 CDS SPAP_0188 NC_014494.1 175031 175234 R Operon 84 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(175031..175234) Streptococcus pneumoniae AP200 9726205 YP_003875785.1 CDS SPAP_0190 NC_014494.1 175756 176331 D Operon 85 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 175756..176331 Streptococcus pneumoniae AP200 9726206 YP_003875786.1 CDS SPAP_0191 NC_014494.1 176514 176798 D Operon 86 Gene 1 COG0438 Glycosyltransferase; glycosyltransferase 176514..176798 Streptococcus pneumoniae AP200 9726207 YP_003875787.1 CDS SPAP_0192 NC_014494.1 176791 177744 D Operon 86 Gene 2 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase 176791..177744 Streptococcus pneumoniae AP200 9726208 YP_003875788.1 CDS SPAP_0193 NC_014494.1 177754 179370 D Operon 86 Gene 3 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 177754..179370 Streptococcus pneumoniae AP200 9726209 YP_003875789.1 CDS SPAP_0194 NC_014494.1 179390 179977 D Operon 86 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 179390..179977 Streptococcus pneumoniae AP200 9726210 YP_003875790.1 CDS SPAP_0195 NC_014494.1 180007 180144 D Operon 86 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 180007..180144 Streptococcus pneumoniae AP200 9726211 YP_003875791.1 CDS SPAP_0196 NC_014494.1 180173 180499 D Operon 86 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 180173..180499 Streptococcus pneumoniae AP200 9726212 YP_003875792.1 CDS SPAP_0197 NC_014494.1 180519 180635 D Operon 86 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 180519..180635 Streptococcus pneumoniae AP200 9726213 YP_003875793.1 CDS SPAP_0198 NC_014494.1 180738 180965 D Operon 87 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 180738..180965 Streptococcus pneumoniae AP200 9726214 YP_003875794.1 CDS SPAP_0199 NC_014494.1 180962 181339 R Operon 88 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 complement(180962..181339) Streptococcus pneumoniae AP200 9726215 YP_003875795.1 CDS SPAP_0200 NC_014494.1 181351 181776 R transposase-like protein, IS1515 complement(181351..181776) Streptococcus pneumoniae AP200 9726216 YP_003875796.1 CDS SPAP_0201 NC_014494.1 182157 182585 D Operon 89 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 182157..182585 Streptococcus pneumoniae AP200 9726217 YP_003875797.1 CDS SPAP_0202 NC_014494.1 182597 183346 D Operon 89 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 182597..183346 Streptococcus pneumoniae AP200 9726218 YP_003875798.1 CDS SPAP_0203 NC_014494.1 183359 183496 D Operon 89 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 183359..183496 Streptococcus pneumoniae AP200 9726219 YP_003875799.1 CDS SPAP_0204 NC_014494.1 183510 184532 D Operon 89 Gene 4 COG1004 Predicted UDP-glucose 6-dehydrogenase; putative UDP-glucose 6-dehydrogenase 183510..184532 Streptococcus pneumoniae AP200 9726220 YP_003875800.1 CDS SPAP_0205 NC_014494.1 184927 185790 D Operon 90 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 184927..185790 Streptococcus pneumoniae AP200 9726221 YP_003875801.1 CDS SPAP_0206 NC_014494.1 186076 186309 D Operon 91 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 186076..186309 Streptococcus pneumoniae AP200 9726222 YP_003875802.1 CDS SPAP_0207 NC_014494.1 186331 187008 D Operon 91 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 186331..187008 Streptococcus pneumoniae AP200 9726223 YP_003875803.1 CDS SPAP_0208 NC_014494.1 187020 187685 D Operon 91 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 187020..187685 Streptococcus pneumoniae AP200 9726224 YP_003875804.1 CDS SPAP_0209 NC_014494.1 187757 188983 D Operon 91 Gene 4 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 187757..188983 Streptococcus pneumoniae AP200 9726225 YP_003875805.1 CDS SPAP_0210 NC_014494.1 189218 189412 R Operon 92 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(189218..189412) Streptococcus pneumoniae AP200 9726226 YP_003875806.1 CDS SPAP_0211 NC_014494.1 189483 190139 D Operon 93 Gene 1 COG1296 Predicted branched-chain amino acid permease (azaleucine resistance); putative branched-chain amino acid permease 189483..190139 Streptococcus pneumoniae AP200 9726227 YP_003875807.1 CDS SPAP_0212 NC_014494.1 190129 190452 D Operon 93 Gene 2 COG4392 Predicted membrane protein; hypothetical protein 190129..190452 Streptococcus pneumoniae AP200 9726228 YP_003875808.1 CDS SPAP_0213 NC_014494.1 190555 191385 D Operon 94 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 190555..191385 Streptococcus pneumoniae AP200 9726229 YP_003875809.1 CDS SPAP_0214 NC_014494.1 191539 192393 D Operon 95 Gene 1 COG1464 ABC-type metal ion transport system, periplasmic component/surface antigen; metal ion ABC transporter periplasmic protein/surface antigen 191539..192393 Streptococcus pneumoniae AP200 9726230 YP_003875810.1 CDS SPAP_0215 NC_014494.1 192493 193866 D Operon 95 Gene 2 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 192493..193866 Streptococcus pneumoniae AP200 9726231 YP_003875811.1 CDS SPAP_0216 NC_014494.1 193859 194920 D Operon 95 Gene 3 COG1135 ABC-type metal ion transport system, ATPase component; metal ion ABC transporter ATPase 193859..194920 Streptococcus pneumoniae AP200 9726232 YP_003875812.1 CDS SPAP_0217 NC_014494.1 194922 195614 D Operon 95 Gene 4 COG2011 ABC-type metal ion transport system, permease component; metal ion ABC transporter permease 194922..195614 Streptococcus pneumoniae AP200 9726233 YP_003875813.1 CDS SPAP_0218 NC_014494.1 195644 196213 R Operon 96 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(195644..196213) Streptococcus pneumoniae AP200 9726234 YP_003875814.1 CDS SPAP_0219 NC_014494.1 196348 196962 D Operon 97 Gene 1 COG5578 Predicted integral membrane protein; putative integral membrane protein 196348..196962 Streptococcus pneumoniae AP200 9726235 YP_003875815.1 CDS SPAP_0220 NC_014494.1 197012 198610 D Operon 97 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 197012..198610 Streptococcus pneumoniae AP200 9726236 YP_003875816.1 CDS SPAP_0221 NC_014494.1 198622 199908 D Operon 97 Gene 3 COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; CheY-like receiver/AraC DNA-binding domain-containing response regulator 198622..199908 Streptococcus pneumoniae AP200 9726237 YP_003875817.1 CDS SPAP_0222 NC_014494.1 199960 200493 D Operon 97 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 199960..200493 Streptococcus pneumoniae AP200 9726238 YP_003875818.1 CDS SPAP_0223 NC_014494.1 200559 201041 D Operon 98 Gene 1 COG1780 Protein involved in ribonucleotide reduction; ribonucleotide reduction protein 200559..201041 Streptococcus pneumoniae AP200 9726239 YP_003875819.1 CDS SPAP_0224 NC_014494.1 201334 202596 R Operon 99 Gene 1 COG1914 Mn2+ and Fe2+ transporters of the NRAMP family; Mn2+ and Fe2+ transporters of the NRAMP family complement(201334..202596) Streptococcus pneumoniae AP200 9726240 YP_003875820.1 CDS SPAP_0225 NC_014494.1 202906 203364 R Operon 100 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(202906..203364) Streptococcus pneumoniae AP200 9726241 YP_003875821.1 CDS SPAP_0226 NC_014494.1 203361 203801 R Operon 100 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator complement(203361..203801) Streptococcus pneumoniae AP200 9726242 YP_003875822.1 CDS SPAP_0227 NC_014494.1 204157 206106 D Operon 101 Gene 1 COG0323 DNA mismatch repair enzyme (predicted ATPase); DNA mismatch repair protein 204157..206106 Streptococcus pneumoniae AP200 9726243 YP_003875823.1 CDS SPAP_0228 NC_014494.1 206431 206898 R Operon 102 Gene 1 COG0054 Riboflavin synthase beta-chain; riboflavin synthase beta-chain complement(206431..206898) Streptococcus pneumoniae AP200 9726244 YP_003875824.1 CDS SPAP_0229 NC_014494.1 206899 208104 R Operon 102 Gene 2 COG0108 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(206899..208104) Streptococcus pneumoniae AP200 9726245 YP_003875825.1 CDS SPAP_0230 NC_014494.1 208124 208759 R Operon 102 Gene 3 COG0307 Riboflavin synthase alpha chain; riboflavin synthase alpha chain complement(208124..208759) Streptococcus pneumoniae AP200 9726246 YP_003875826.1 CDS SPAP_0231 NC_014494.1 208744 209844 R Operon 102 Gene 4 COG1985 Pyrimidine reductase, riboflavin biosynthesis; pyrimidine reductase, riboflavin biosynthesis complement(208744..209844) Streptococcus pneumoniae AP200 9726247 YP_003875827.1 CDS SPAP_0232 NC_014494.1 209935 210144 D Operon 103 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 209935..210144 Streptococcus pneumoniae AP200 9726248 YP_003875828.1 CDS SPAP_0233 NC_014494.1 210250 210843 D Operon 104 Gene 1 COG0632 Holliday junction resolvasome, DNA-binding subunit; Holliday junction resolvasome DNA-binding subunit 210250..210843 Streptococcus pneumoniae AP200 9726249 YP_003875829.1 CDS SPAP_0234 NC_014494.1 210853 211416 D Operon 104 Gene 2 COG2818 3-methyladenine DNA glycosylase; 3-methyladenine DNA glycosylase 210853..211416 Streptococcus pneumoniae AP200 9726250 YP_003875830.1 CDS SPAP_0235 NC_014494.1 211416 212090 D Operon 104 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 211416..212090 Streptococcus pneumoniae AP200 9726251 YP_003875831.1 CDS SPAP_0236 NC_014494.1 212245 213276 R Operon 105 Gene 1 COG1619 Uncharacterized proteins, homologs of microcin C7 resistance protein MccF; hypothetical protein complement(212245..213276) Streptococcus pneumoniae AP200 9726252 YP_003875832.1 CDS SPAP_0237 NC_014494.1 213531 214214 R Operon 106 Gene 1 COG4858 Uncharacterized membrane-bound protein conserved in bacteria; hypothetical protein complement(213531..214214) Streptococcus pneumoniae AP200 9726253 YP_003875833.1 CDS SPAP_0238 NC_014494.1 214226 215170 R Operon 106 Gene 2 COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter complement(214226..215170) Streptococcus pneumoniae AP200 9726254 YP_003875834.1 CDS SPAP_0239 NC_014494.1 215302 218133 D Operon 107 Gene 1 COG0178 Excinuclease ATPase subunit; excinuclease ATPase subunit 215302..218133 Streptococcus pneumoniae AP200 9726255 YP_003875835.1 CDS SPAP_0240 NC_014494.1 218126 219187 D Operon 107 Gene 2 COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 218126..219187 Streptococcus pneumoniae AP200 9726256 YP_003875836.1 CDS SPAP_0241 NC_014494.1 219319 219717 D Operon 108 Gene 1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein 219319..219717 Streptococcus pneumoniae AP200 9726257 YP_003875837.1 CDS SPAP_0242 NC_014494.1 219783 220352 D Operon 108 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 219783..220352 Streptococcus pneumoniae AP200 9726258 YP_003875838.1 CDS SPAP_0243 NC_014494.1 220439 220705 D Operon 109 Gene 1 COG4472 Uncharacterized protein conserved in bacteria; hypothetical protein 220439..220705 Streptococcus pneumoniae AP200 9726259 YP_003875839.1 CDS SPAP_0244 NC_014494.1 220709 221128 D Operon 109 Gene 2 COG0816 Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); putative endonuclease 220709..221128 Streptococcus pneumoniae AP200 9726260 YP_003875840.1 CDS SPAP_0245 NC_014494.1 221144 221449 D Operon 109 Gene 3 COG3906 Uncharacterized protein conserved in bacteria; hypothetical protein 221144..221449 Streptococcus pneumoniae AP200 9726261 YP_003875841.1 CDS SPAP_0246 NC_014494.1 221707 222957 D Operon 110 Gene 1 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 221707..222957 Streptococcus pneumoniae AP200 9726262 YP_003875842.1 CDS SPAP_0247 NC_014494.1 223041 223499 D Operon 110 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 223041..223499 Streptococcus pneumoniae AP200 9726263 YP_003875843.1 CDS SPAP_0248 NC_014494.1 223672 225177 D Operon 111 Gene 1 COG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes; phosphatidylserine/ phosphatidylglycerophosphate/cardioli pin synthases-like enzyme 223672..225177 Streptococcus pneumoniae AP200 9726264 YP_003875844.1 CDS SPAP_0249 NC_014494.1 225255 225398 D Operon 111 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 225255..225398 Streptococcus pneumoniae AP200 9726265 YP_003875845.1 CDS SPAP_0250 NC_014494.1 225435 226973 D Operon 111 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 225435..226973 Streptococcus pneumoniae AP200 9726266 YP_003875846.1 CDS SPAP_0251 NC_014494.1 227093 229300 D Operon 112 Gene 1 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; oxygen-sensitive ribonucleoside-triphosphate reductase 227093..229300 Streptococcus pneumoniae AP200 9726267 YP_003875847.1 CDS SPAP_0252 NC_014494.1 229312 229452 D Operon 112 Gene 2 protein supported gi|15900139|ref|NP_344743.1| hypothetical protein SP_0203; hypothetical protein 229312..229452 Streptococcus pneumoniae AP200 9726268 YP_003875848.1 CDS SPAP_0253 NC_014494.1 229496 230002 D Operon 112 Gene 3 COG3981 Predicted acetyltransferase; putative acetyltransferase 229496..230002 Streptococcus pneumoniae AP200 9726269 YP_003875849.1 CDS SPAP_0254 NC_014494.1 229995 230585 D Operon 112 Gene 4 COG0602 Organic radical activating enzymes; organic radical activating enzyme 229995..230585 Streptococcus pneumoniae AP200 9726270 YP_003875850.1 CDS SPAP_0255 NC_014494.1 230582 231166 D Operon 112 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 230582..231166 Streptococcus pneumoniae AP200 9726271 YP_003875851.1 CDS SPAP_0256 NC_014494.1 231466 231774 D Operon 113 Gene 1 protein supported gi|15900144|ref|NP_344748.1| 30S ribosomal protein S10; hypothetical protein 231466..231774 Streptococcus pneumoniae AP200 9726272 YP_003875852.1 CDS SPAP_0257 NC_014494.1 231991 232617 D Operon 113 Gene 2 protein supported gi|15900145|ref|NP_344749.1| 50S ribosomal protein L3; 50S ribosomal protein L3 231991..232617 Streptococcus pneumoniae AP200 9726273 YP_003875853.1 CDS SPAP_0258 NC_014494.1 232642 233265 D Operon 113 Gene 3 protein supported gi|15900146|ref|NP_344750.1| 50S ribosomal protein L4; hypothetical protein 232642..233265 Streptococcus pneumoniae AP200 9726274 YP_003875854.1 CDS SPAP_0259 NC_014494.1 233265 233561 D Operon 113 Gene 4 protein supported gi|15900147|ref|NP_344751.1| 50S ribosomal protein L23; hypothetical protein 233265..233561 Streptococcus pneumoniae AP200 9726275 YP_003875855.1 CDS SPAP_0260 NC_014494.1 233579 234412 D Operon 113 Gene 5 protein supported gi|15900148|ref|NP_344752.1| 50S ribosomal protein L2; hypothetical protein 233579..234412 Streptococcus pneumoniae AP200 9726276 YP_003875856.1 CDS SPAP_0261 NC_014494.1 234516 234797 D Operon 113 Gene 6 protein supported gi|15900149|ref|NP_344753.1| 30S ribosomal protein S19; hypothetical protein 234516..234797 Streptococcus pneumoniae AP200 9726277 YP_003875857.1 CDS SPAP_0262 NC_014494.1 234658 235113 R Operon 114 Gene 1 protein supported gi|15902237|ref|NP_357787.1| hypothetical protein spr0193; hypothetical protein complement(234658..235113) Streptococcus pneumoniae AP200 9726278 YP_003875858.1 CDS SPAP_0263 NC_014494.1 234809 235153 D Operon 115 Gene 1 COG0091 Ribosomal protein L22; 50S ribosomal protein L22 234809..235153 Streptococcus pneumoniae AP200 9726279 YP_003875859.1 CDS SPAP_0264 NC_014494.1 235166 235819 D Operon 115 Gene 2 protein supported gi|15900151|ref|NP_344755.1| 30S ribosomal protein S3; 30S ribosomal protein S3 235166..235819 Streptococcus pneumoniae AP200 9726280 YP_003875860.1 CDS SPAP_0265 NC_014494.1 235823 236236 D Operon 115 Gene 3 protein supported gi|15900152|ref|NP_344756.1| 50S ribosomal protein L16; 50S ribosomal protein L16 235823..236236 Streptococcus pneumoniae AP200 9726281 YP_003875861.1 CDS SPAP_0266 NC_014494.1 236246 236452 D Operon 115 Gene 4 protein supported gi|15900153|ref|NP_344757.1| 50S ribosomal protein L29; hypothetical protein 236246..236452 Streptococcus pneumoniae AP200 9726282 YP_003875862.1 CDS SPAP_0267 NC_014494.1 236477 236737 D Operon 115 Gene 5 protein supported gi|15900154|ref|NP_344758.1| 30S ribosomal protein S17; 30S ribosomal protein S17 236477..236737 Streptococcus pneumoniae AP200 9726283 YP_003875863.1 CDS SPAP_0268 NC_014494.1 236763 237131 D Operon 115 Gene 6 protein supported gi|15900155|ref|NP_344759.1| 50S ribosomal protein L14; 50S ribosomal protein L14 236763..237131 Streptococcus pneumoniae AP200 9726284 YP_003875864.1 CDS SPAP_0269 NC_014494.1 237209 237514 D Operon 115 Gene 7 protein supported gi|15900156|ref|NP_344760.1| 50S ribosomal protein L24; hypothetical protein 237209..237514 Streptococcus pneumoniae AP200 9726285 YP_003875865.1 CDS SPAP_0270 NC_014494.1 237538 238080 D Operon 115 Gene 8 protein supported gi|15900157|ref|NP_344761.1| 50S ribosomal protein L5; 50S ribosomal protein L5 237538..238080 Streptococcus pneumoniae AP200 9726286 YP_003875866.1 CDS SPAP_0271 NC_014494.1 238098 238367 D Operon 115 Gene 9 protein supported gi|15900158|ref|NP_344762.1| 30S ribosomal protein S14; hypothetical protein 238098..238367 Streptococcus pneumoniae AP200 9726287 YP_003875867.1 CDS SPAP_0272 NC_014494.1 238653 239051 D Operon 115 Gene 10 protein supported gi|15900160|ref|NP_344764.1| 30S ribosomal protein S8; 30S ribosomal protein S8 238653..239051 Streptococcus pneumoniae AP200 9726288 YP_003875868.1 CDS SPAP_0273 NC_014494.1 239243 239779 D Operon 115 Gene 11 protein supported gi|148996647|ref|ZP_01824365.1| 50S ribosomal protein L6; 50S ribosomal protein L6 239243..239779 Streptococcus pneumoniae AP200 9726289 YP_003875869.1 CDS SPAP_0274 NC_014494.1 239824 240219 D Operon 115 Gene 12 protein supported gi|182683204|ref|YP_001834951.1| 50S ribosomal protein L18; 50S ribosomal protein L18 239824..240219 Streptococcus pneumoniae AP200 9726290 YP_003875870.1 CDS SPAP_0275 NC_014494.1 240237 240731 D Operon 115 Gene 13 protein supported gi|15900163|ref|NP_344767.1| 30S ribosomal protein S5; 30S ribosomal protein S5 240237..240731 Streptococcus pneumoniae AP200 9726291 YP_003875871.1 CDS SPAP_0276 NC_014494.1 240703 240927 D Operon 115 Gene 14 protein supported gi|182683206|ref|YP_001834953.1| 50S ribosomal protein L30; hypothetical protein 240703..240927 Streptococcus pneumoniae AP200 9726292 YP_003875872.1 CDS SPAP_0277 NC_014494.1 241072 241512 D Operon 115 Gene 15 protein supported gi|15900165|ref|NP_344769.1| 50S ribosomal protein L15; 50S ribosomal protein L15 241072..241512 Streptococcus pneumoniae AP200 9726293 YP_003875873.1 CDS SPAP_0278 NC_014494.1 241525 242835 D Operon 115 Gene 16 COG0201 Preprotein translocase subunit SecY; preprotein translocase subunit SecY 241525..242835 Streptococcus pneumoniae AP200 9726294 YP_003875874.1 CDS SPAP_0279 NC_014494.1 242986 243624 D Operon 115 Gene 17 COG0563 Adenylate kinase and related kinases; adenylate kinase-like kinase 242986..243624 Streptococcus pneumoniae AP200 9726295 YP_003875875.1 CDS SPAP_0280 NC_014494.1 243741 243959 D Operon 116 Gene 1 protein supported gi|15900168|ref|NP_344772.1| translation initiation factor IF-1; hypothetical protein 243741..243959 Streptococcus pneumoniae AP200 9726296 YP_003875876.1 CDS SPAP_0281 NC_014494.1 243984 244100 D Operon 116 Gene 2 COG0257 Ribosomal protein L36; ribosomal protein L36 243984..244100 Streptococcus pneumoniae AP200 9726297 YP_003875877.1 CDS SPAP_0282 NC_014494.1 244118 244483 D Operon 116 Gene 3 protein supported gi|15900170|ref|NP_344774.1| 30S ribosomal protein S13; 30S ribosomal protein S13 244118..244483 Streptococcus pneumoniae AP200 9726298 YP_003875878.1 CDS SPAP_0283 NC_014494.1 244501 244884 D Operon 116 Gene 4 protein supported gi|15900171|ref|NP_344775.1| 30S ribosomal protein S11; 30S ribosomal protein S11 244501..244884 Streptococcus pneumoniae AP200 9726299 YP_003875879.1 CDS SPAP_0284 NC_014494.1 244927 245862 D Operon 116 Gene 5 COG0202 DNA-directed RNA polymerase, alpha subunit/40 kD subunit; DNA-directed RNA polymerase subunit alpha/40 kD subunit 244927..245862 Streptococcus pneumoniae AP200 9726300 YP_003875880.1 CDS SPAP_0285 NC_014494.1 245874 246260 D Operon 116 Gene 6 protein supported gi|15902260|ref|NP_357810.1| 50S ribosomal protein L17; hypothetical protein 245874..246260 Streptococcus pneumoniae AP200 9726301 YP_003875881.1 CDS SPAP_0286 NC_014494.1 246525 246791 D Operon 117 Gene 1 COG3830 ACT domain-containing protein; ACT domain-containing protein 246525..246791 Streptococcus pneumoniae AP200 9726302 YP_003875882.1 CDS SPAP_0287 NC_014494.1 246801 248138 D Operon 117 Gene 2 COG2848 Uncharacterized conserved protein; hypothetical protein 246801..248138 Streptococcus pneumoniae AP200 9726303 YP_003875883.1 CDS SPAP_0288 NC_014494.1 248382 249074 D Operon 118 Gene 1 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase 248382..249074 Streptococcus pneumoniae AP200 9726304 YP_003875884.1 CDS SPAP_0289 NC_014494.1 249177 250199 R Operon 119 Gene 1 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease complement(249177..250199) Streptococcus pneumoniae AP200 9726305 YP_003875885.1 CDS SPAP_0290 NC_014494.1 250196 250564 R Operon 119 Gene 2 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease complement(250196..250564) Streptococcus pneumoniae AP200 9726306 YP_003875886.1 CDS SPAP_0291 NC_014494.1 250812 251762 R Operon 119 Gene 3 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase complement(250812..251762) Streptococcus pneumoniae AP200 9726307 YP_003875887.1 CDS SPAP_0292 NC_014494.1 251915 252931 R Operon 119 Gene 4 COG1840 ABC-type Fe3+ transport system, periplasmic component; Fe3+ ABC transporter periplasmic protein complement(251915..252931) Streptococcus pneumoniae AP200 9726308 YP_003875888.1 CDS SPAP_0293 NC_014494.1 253148 253345 R Operon 120 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(253148..253345) Streptococcus pneumoniae AP200 9726309 YP_003875889.1 CDS SPAP_0294 NC_014494.1 253420 254196 R Operon 120 Gene 2 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate-formate lyase-activating enzyme complement(253420..254196) Streptococcus pneumoniae AP200 9726310 YP_003875890.1 CDS SPAP_0295 NC_014494.1 254318 255064 D Operon 121 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 254318..255064 Streptococcus pneumoniae AP200 9726311 YP_003875891.1 CDS SPAP_0296 NC_014494.1 255077 256057 D Operon 121 Gene 2 COG2390 Transcriptional regulator, contains sigma factor-related N-terminal domain; transcriptional regulator 255077..256057 Streptococcus pneumoniae AP200 9726312 YP_003875892.1 CDS SPAP_0297 NC_014494.1 256252 256572 D Operon 122 Gene 1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 256252..256572 Streptococcus pneumoniae AP200 9726313 YP_003875893.1 CDS SPAP_0298 NC_014494.1 256618 256926 D Operon 122 Gene 2 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 256618..256926 Streptococcus pneumoniae AP200 9726314 YP_003875894.1 CDS SPAP_0299 NC_014494.1 256943 258241 D Operon 122 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 256943..258241 Streptococcus pneumoniae AP200 9726315 YP_003875895.1 CDS SPAP_0300 NC_014494.1 258392 260830 D Operon 123 Gene 1 COG1882 Pyruvate-formate lyase; pyruvate-formate lyase 258392..260830 Streptococcus pneumoniae AP200 9726316 YP_003875896.1 CDS SPAP_0301 NC_014494.1 260849 261517 D Operon 123 Gene 2 COG0176 Transaldolase; transaldolase 260849..261517 Streptococcus pneumoniae AP200 9726317 YP_003875897.1 CDS SPAP_0302 NC_014494.1 261535 262623 D Operon 123 Gene 3 COG0371 Glycerol dehydrogenase and related enzymes; glycerol dehydrogenase 261535..262623 Streptococcus pneumoniae AP200 9726318 YP_003875898.1 CDS SPAP_0303 NC_014494.1 263078 265579 D Operon 124 Gene 1 COG0495 Leucyl-tRNA synthetase; leucyl-tRNA synthetase 263078..265579 Streptococcus pneumoniae AP200 9726319 YP_003875899.1 CDS SPAP_0304 NC_014494.1 265773 266468 D Operon 125 Gene 1 protein supported gi|116627318|ref|YP_819937.1| acetyltransferase; hypothetical protein 265773..266468 Streptococcus pneumoniae AP200 9726320 YP_003875900.1 CDS SPAP_0305 NC_014494.1 266480 266896 D Operon 125 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 266480..266896 Streptococcus pneumoniae AP200 9726321 YP_003875901.1 CDS SPAP_0306 NC_014494.1 267711 267803 R Operon 126 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(267711..267803) Streptococcus pneumoniae AP200 9726322 YP_003875902.1 CDS SPAP_0307 NC_014494.1 267937 268935 D Operon 127 Gene 1 COG2255 Holliday junction resolvasome, helicase subunit; Holliday junction resolvasome helicase subunit 267937..268935 Streptococcus pneumoniae AP200 9726323 YP_003875903.1 CDS SPAP_0308 NC_014494.1 268916 269023 D Operon 127 Gene 2 COG3575 Uncharacterized protein conserved in bacteria; hypothetical protein 268916..269023 Streptococcus pneumoniae AP200 9726324 YP_003875904.1 CDS SPAP_0309 NC_014494.1 269024 269488 D Operon 127 Gene 3 COG3575 Uncharacterized protein conserved in bacteria; hypothetical protein 269024..269488 Streptococcus pneumoniae AP200 9726325 YP_003875905.1 CDS SPAP_0310 NC_014494.1 269719 270477 D Operon 128 Gene 1 COG0020 Undecaprenyl pyrophosphate synthase; Undecaprenyl pyrophosphate synthase 269719..270477 Streptococcus pneumoniae AP200 9726326 YP_003875906.1 CDS SPAP_0311 NC_014494.1 270486 271289 D Operon 128 Gene 2 COG0575 CDP-diglyceride synthetase; CDP-diglyceride synthetase 270486..271289 Streptococcus pneumoniae AP200 9726327 YP_003875907.1 CDS SPAP_0312 NC_014494.1 271311 272570 D Operon 128 Gene 3 COG0750 Predicted membrane-associated Zn-dependent proteases 1; hypothetical protein 271311..272570 Streptococcus pneumoniae AP200 9726328 YP_003875908.1 CDS SPAP_0313 NC_014494.1 272583 274436 D Operon 128 Gene 4 COG0442 Prolyl-tRNA synthetase; prolyl-tRNA synthetase 272583..274436 Streptococcus pneumoniae AP200 9726329 YP_003875909.1 CDS SPAP_0314 NC_014494.1 274536 275915 D Operon 129 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 274536..275915 Streptococcus pneumoniae AP200 9726330 YP_003875910.1 CDS SPAP_0315 NC_014494.1 276107 277915 D Operon 130 Gene 1 COG0449 Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains; glucosamine 6-phosphate synthetase 276107..277915 Streptococcus pneumoniae AP200 9726331 YP_003875911.1 CDS SPAP_0316 NC_014494.1 278186 279235 D Operon 131 Gene 1 protein supported gi|15900201|ref|NP_344805.1| hypothetical protein SP_0267; hypothetical protein 278186..279235 Streptococcus pneumoniae AP200 9726332 YP_003875912.1 CDS SPAP_0317 NC_014494.1 279335 283177 R Operon 132 Gene 1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; type II secretory pathway pullulanase PulA-like glycosidase complement(279335..283177) Streptococcus pneumoniae AP200 9726333 YP_003875913.1 CDS SPAP_0318 NC_014494.1 283594 284007 D Operon 133 Gene 1 protein supported gi|15900205|ref|NP_344809.1| 30S ribosomal protein S12; 30S ribosomal protein S12 283594..284007 Streptococcus pneumoniae AP200 9726334 YP_003875914.1 CDS SPAP_0319 NC_014494.1 284027 284497 D Operon 133 Gene 2 protein supported gi|15902293|ref|NP_357843.1| 30S ribosomal protein S7; 30S ribosomal protein S7 284027..284497 Streptococcus pneumoniae AP200 9726335 YP_003875915.1 CDS SPAP_0320 NC_014494.1 284922 287003 D Operon 133 Gene 3 COG0480 Translation elongation factors (GTPases); translation elongation factor 284922..287003 Streptococcus pneumoniae AP200 9726336 YP_003875916.1 CDS SPAP_0321 NC_014494.1 287107 291498 D Operon 134 Gene 1 COG2176 DNA polymerase III, alpha subunit (gram-positive type); DNA polymerase III subunit alpha 287107..291498 Streptococcus pneumoniae AP200 9726337 YP_003875917.1 CDS SPAP_0322 NC_014494.1 291600 291863 D Operon 135 Gene 1 COG3077 DNA-damage-inducible protein J; DNA-damage-inducible protein J 291600..291863 Streptococcus pneumoniae AP200 9726338 YP_003875918.1 CDS SPAP_0323 NC_014494.1 291856 292134 D Operon 135 Gene 2 COG3041 Uncharacterized protein conserved in bacteria; hypothetical protein 291856..292134 Streptococcus pneumoniae AP200 9726339 YP_003875919.1 CDS SPAP_0324 NC_014494.1 292155 292307 D Operon 135 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 292155..292307 Streptococcus pneumoniae AP200 9726340 YP_003875920.1 CDS SPAP_0325 NC_014494.1 292329 293570 D Operon 135 Gene 4 COG2309 Leucyl aminopeptidase (aminopeptidase T); leucyl aminopeptidase 292329..293570 Streptococcus pneumoniae AP200 9726341 YP_003875921.1 CDS SPAP_0326 NC_014494.1 293580 293810 D Operon 135 Gene 5 COG2261 Predicted membrane protein; hypothetical protein 293580..293810 Streptococcus pneumoniae AP200 9726342 YP_003875922.1 CDS SPAP_0327 NC_014494.1 294078 294800 D Operon 136 Gene 1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase 294078..294800 Streptococcus pneumoniae AP200 9726343 YP_003875923.1 CDS SPAP_0328 NC_014494.1 295017 296351 D Operon 137 Gene 1 COG3579 Aminopeptidase C; aminopeptidase C 295017..296351 Streptococcus pneumoniae AP200 9726344 YP_003875924.1 CDS SPAP_0329 NC_014494.1 296407 297318 R Operon 138 Gene 1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID complement(296407..297318) Streptococcus pneumoniae AP200 9726345 YP_003875925.1 CDS SPAP_0330 NC_014494.1 297342 298145 R Operon 138 Gene 2 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC complement(297342..298145) Streptococcus pneumoniae AP200 9726346 YP_003875926.1 CDS SPAP_0331 NC_014494.1 298173 299162 R Operon 138 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB complement(298173..299162) Streptococcus pneumoniae AP200 9726347 YP_003875927.1 CDS SPAP_0332 NC_014494.1 299394 300413 R Operon 139 Gene 1 COG1064 Zn-dependent alcohol dehydrogenases; Zn-dependent alcohol dehydrogenase complement(299394..300413) Streptococcus pneumoniae AP200 9726348 YP_003875928.1 CDS SPAP_0333 NC_014494.1 300752 301564 R Operon 140 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(300752..301564) Streptococcus pneumoniae AP200 9726349 YP_003875929.1 CDS SPAP_0334 NC_014494.1 301754 303172 D Operon 141 Gene 1 COG2252 Permeases; permease 301754..303172 Streptococcus pneumoniae AP200 9726350 YP_003875930.1 CDS SPAP_0335 NC_014494.1 303225 303932 D Operon 141 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 303225..303932 Streptococcus pneumoniae AP200 9726351 YP_003875931.1 CDS SPAP_0336 NC_014494.1 304030 305001 D Operon 142 Gene 1 COG0294 Dihydropteroate synthase and related enzymes; dihydropteroate synthase-like enzyme 304030..305001 Streptococcus pneumoniae AP200 9726352 YP_003875932.1 CDS SPAP_0337 NC_014494.1 305003 306325 D Operon 142 Gene 2 COG0285 Folylpolyglutamate synthase; folylpolyglutamate synthase 305003..306325 Streptococcus pneumoniae AP200 9726353 YP_003875933.1 CDS SPAP_0338 NC_014494.1 306306 306860 D Operon 142 Gene 3 COG0302 GTP cyclohydrolase I; GTP cyclohydrolase I 306306..306860 Streptococcus pneumoniae AP200 9726354 YP_003875934.1 CDS SPAP_0339 NC_014494.1 306903 307715 D Operon 142 Gene 4 protein supported gi|148994682|ref|ZP_01823786.1| 50S ribosomal protein L13; hypothetical protein 306903..307715 Streptococcus pneumoniae AP200 9726355 YP_003875935.1 CDS SPAP_0340 NC_014494.1 307865 308182 R Operon 143 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(307865..308182) Streptococcus pneumoniae AP200 9726356 YP_003875936.1 CDS SPAP_0341 NC_014494.1 308539 308985 D Operon 144 Gene 1 protein supported gi|15900228|ref|NP_344832.1| 50S ribosomal protein L13; hypothetical protein 308539..308985 Streptococcus pneumoniae AP200 9726357 YP_003875937.1 CDS SPAP_0342 NC_014494.1 309004 309396 D Operon 144 Gene 2 protein supported gi|15902316|ref|NP_357866.1| 30S ribosomal protein S9; 30S ribosomal protein S9 309004..309396 Streptococcus pneumoniae AP200 9726358 YP_003875938.1 CDS SPAP_0343 NC_014494.1 309657 310079 R Operon 145 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(309657..310079) Streptococcus pneumoniae AP200 9726359 YP_003875939.1 CDS SPAP_0344 NC_014494.1 310226 310402 D Operon 146 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 310226..310402 Streptococcus pneumoniae AP200 9726360 YP_003875940.1 CDS SPAP_0345 NC_014494.1 310803 313016 D Operon 147 Gene 1 COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases; alpha-glucosidase 310803..313016 Streptococcus pneumoniae AP200 9726361 YP_003875941.1 CDS SPAP_0346 NC_014494.1 313238 313714 R Operon 148 Gene 1 COG0386 Glutathione peroxidase; glutathione peroxidase complement(313238..313714) Streptococcus pneumoniae AP200 9726362 YP_003875942.1 CDS SPAP_0347 NC_014494.1 313937 317140 D hyaluronidase; hypothetical protein 313937..317140 Streptococcus pneumoniae AP200 9726363 YP_003875943.1 CDS SPAP_0348 NC_014494.1 317679 317912 D Operon 150 Gene 1 protein supported gi|148996730|ref|ZP_01824448.1| 30S ribosomal protein S9; hypothetical protein 317679..317912 Streptococcus pneumoniae AP200 9726364 YP_003875944.1 CDS SPAP_0349 NC_014494.1 318288 318917 R Operon 151 Gene 1 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; 2-keto-3-deoxy-6-phosphogluconate aldolase complement(318288..318917) Streptococcus pneumoniae AP200 9726365 YP_003875945.1 CDS SPAP_0350 NC_014494.1 318927 319928 R Operon 151 Gene 2 COG0524 Sugar kinases, ribokinase family; sugar kinase complement(318927..319928) Streptococcus pneumoniae AP200 9726366 YP_003875946.1 CDS SPAP_0351 NC_014494.1 319959 320600 R Operon 151 Gene 3 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB complement(319959..320600) Streptococcus pneumoniae AP200 9726367 YP_003875947.1 CDS SPAP_0352 NC_014494.1 320619 321434 R Operon 151 Gene 4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase complement(320619..321434) Streptococcus pneumoniae AP200 9726368 YP_003875948.1 CDS SPAP_0353 NC_014494.1 321706 322140 D Operon 152 Gene 1 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA 321706..322140 Streptococcus pneumoniae AP200 9726369 YP_003875949.1 CDS SPAP_0354 NC_014494.1 322152 323342 D Operon 152 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 322152..323342 Streptococcus pneumoniae AP200 9726370 YP_003875950.1 CDS SPAP_0355 NC_014494.1 323353 323844 D Operon 152 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB 323353..323844 Streptococcus pneumoniae AP200 9726371 YP_003875951.1 CDS SPAP_0356 NC_014494.1 323859 324638 D Operon 152 Gene 4 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC 323859..324638 Streptococcus pneumoniae AP200 9726372 YP_003875952.1 CDS SPAP_0357 NC_014494.1 324625 325443 D Operon 152 Gene 5 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID 324625..325443 Streptococcus pneumoniae AP200 9726373 YP_003875953.1 CDS SPAP_0358 NC_014494.1 325455 325736 D Operon 152 Gene 6 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC 325455..325736 Streptococcus pneumoniae AP200 9726374 YP_003875954.1 CDS SPAP_0359 NC_014494.1 325758 327659 D Operon 152 Gene 7 Putative gene predicted by FgenesB; hypothetical protein 325758..327659 Streptococcus pneumoniae AP200 9726375 YP_003875955.1 CDS SPAP_0360 NC_014494.1 327719 328720 D Operon 152 Gene 8 COG1609 Transcriptional regulators; transcriptional regulator 327719..328720 Streptococcus pneumoniae AP200 9726376 YP_003875956.1 CDS SPAP_0361 NC_014494.1 328830 329165 R Operon 153 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(328830..329165) Streptococcus pneumoniae AP200 9726377 YP_003875957.1 CDS SPAP_0362 NC_014494.1 329176 329418 R Operon 153 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(329176..329418) Streptococcus pneumoniae AP200 9726378 YP_003875958.1 CDS SPAP_0363 NC_014494.1 329677 329970 R Operon 154 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(329677..329970) Streptococcus pneumoniae AP200 9726379 YP_003875959.1 CDS SPAP_0364 NC_014494.1 329986 330180 R Operon 154 Gene 2 COG1476 Predicted transcriptional regulators; putative transcriptional regulator complement(329986..330180) Streptococcus pneumoniae AP200 9726380 YP_003875960.1 CDS SPAP_0365 NC_014494.1 330346 331296 D Operon 155 Gene 1 COG0275 Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; putative S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis 330346..331296 Streptococcus pneumoniae AP200 9726381 YP_003875961.1 CDS SPAP_0366 NC_014494.1 331308 331625 D Operon 155 Gene 2 COG4839 Protein required for the initiation of cell division; cell division initiation protein 331308..331625 Streptococcus pneumoniae AP200 9726382 YP_003875962.1 CDS SPAP_0367 NC_014494.1 331629 333881 D Operon 155 Gene 3 COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein FtsI 331629..333881 Streptococcus pneumoniae AP200 9726383 YP_003875963.1 CDS SPAP_0368 NC_014494.1 333883 334863 D Operon 155 Gene 4 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase 333883..334863 Streptococcus pneumoniae AP200 9726384 YP_003875964.1 CDS SPAP_0369 NC_014494.1 335427 337532 D Operon 156 Gene 1 protein supported gi|163764771|ref|ZP_02171825.1| ribosomal protein S8; hypothetical protein 335427..337532 Streptococcus pneumoniae AP200 9726385 YP_003875965.1 CDS SPAP_0370 NC_014494.1 337828 338310 R Operon 157 Gene 1 COG1854 LuxS protein involved in autoinducer AI2 synthesis; LuxS protein involved in autoinducer AI2 synthesis complement(337828..338310) Streptococcus pneumoniae AP200 9726386 YP_003875966.1 CDS SPAP_0371 NC_014494.1 338405 339889 R Operon 157 Gene 2 COG4868 Uncharacterized protein conserved in bacteria; hypothetical protein complement(338405..339889) Streptococcus pneumoniae AP200 9726387 YP_003875967.1 CDS SPAP_0372 NC_014494.1 340042 341652 D Operon 158 Gene 1 COG0366 Glycosidases; glucan 1,6-alpha-glucosidase 340042..341652 Streptococcus pneumoniae AP200 9726388 YP_003875968.1 CDS SPAP_0373 NC_014494.1 341783 343192 R transposase-like protein, IS1202 complement(341783..343192) Streptococcus pneumoniae AP200 9726389 YP_003875969.1 CDS wzg NC_014494.1 343368 344813 D Operon 160 Gene 1 COG1316 Transcriptional regulator; integral membrane regulatory protein Wzg 343368..344813 Streptococcus pneumoniae AP200 9726390 YP_003875970.1 CDS wzh NC_014494.1 344815 345546 D Operon 160 Gene 2 COG4464 Capsular polysaccharide biosynthesis protein; protein-tyrosine phosphatase Wzh 344815..345546 Streptococcus pneumoniae AP200 9726391 YP_003875971.1 CDS wzd NC_014494.1 345555 346247 D Operon 160 Gene 3 COG3944 Capsular polysaccharide biosynthesis protein; capsular polysaccharide biosynthesis protein Wzd 345555..346247 Streptococcus pneumoniae AP200 9726392 YP_003875972.1 CDS wze NC_014494.1 346257 346946 D Operon 160 Gene 4 COG0489 ATPases involved in chromosome partitioning; tyrosine-protein kinase Wze 346257..346946 Streptococcus pneumoniae AP200 9726393 YP_003875973.1 CDS wchA NC_014494.1 346961 348322 D Operon 160 Gene 5 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; undecaprenylphosphate glucosephosphotransferase WchA (initial sugar transferase) 346961..348322 Streptococcus pneumoniae AP200 9726394 YP_003875974.1 CDS wchJ NC_014494.1 348326 348775 D Operon 160 Gene 6 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; putative glycosyl transferase enhancer 348326..348775 Streptococcus pneumoniae AP200 9726395 YP_003875975.1 CDS wchK NC_014494.1 348775 349254 D Operon 160 Gene 7 COG5017 Uncharacterized conserved protein; putative glycosyl transferase 348775..349254 Streptococcus pneumoniae AP200 9726396 YP_003875976.1 CDS wcyK NC_014494.1 349496 350593 D Operon 161 Gene 1 COG0438 Glycosyltransferase; putative glycosyl transferase 349496..350593 Streptococcus pneumoniae AP200 9726397 YP_003875977.1 CDS wcwC NC_014494.1 350615 351274 D Operon 161 Gene 2 COG3955 Exopolysaccharide biosynthesis protein; putative acetyl transferase 350615..351274 Streptococcus pneumoniae AP200 9726398 YP_003875978.1 CDS wcrL NC_014494.1 351271 351993 D Operon 161 Gene 3 COG3774 Mannosyltransferase OCH1 and related enzymes; putative glycosyl transferase 351271..351993 Streptococcus pneumoniae AP200 9726399 YP_003875979.1 CDS wzy NC_014494.1 351990 353162 D oligosaccharide repeat unit polymerase Wzy 351990..353162 Streptococcus pneumoniae AP200 9726400 YP_003875980.1 CDS wcwT NC_014494.1 353152 353652 D Operon 161 Gene 5 COG0110 Acetyltransferase (isoleucine patch superfamily); putative acetyl transferase 353152..353652 Streptococcus pneumoniae AP200 9726401 YP_003875981.1 CDS wcwU NC_014494.1 353662 354849 D Operon 161 Gene 6 COG1887 Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC; putative glycerol phosphotransferase 353662..354849 Streptococcus pneumoniae AP200 9726402 YP_003875982.1 CDS wzx NC_014494.1 354806 356269 D Operon 161 Gene 7 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; flippase Wzx 354806..356269 Streptococcus pneumoniae AP200 9726403 YP_003875983.1 CDS gct NC_014494.1 356383 356775 D Operon 162 Gene 1 COG0615 Cytidylyltransferase; CDP-glycerol-1-phosphate biosynthetic protein Gct 356383..356775 Streptococcus pneumoniae AP200 9726404 YP_003875984.1 CDS wcjE NC_014494.1 357137 358165 D putative acetyl transferase 357137..358165 Streptococcus pneumoniae AP200 9726405 YP_003875985.1 CDS SPAP_0390 NC_014494.1 358343 360325 D Operon 164 Gene 1 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic protein 358343..360325 Streptococcus pneumoniae AP200 9726406 YP_003875986.1 CDS SPAP_0391 NC_014494.1 360329 360520 D Operon 164 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 360329..360520 Streptococcus pneumoniae AP200 9726407 YP_003875987.1 CDS SPAP_0392 NC_014494.1 360626 365929 D cell wall surface anchor family protein; hypothetical protein 360626..365929 Streptococcus pneumoniae AP200 9726408 YP_003875988.1 CDS SPAP_0393 NC_014494.1 366096 368255 R Operon 166 Gene 1 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase complement(366096..368255) Streptococcus pneumoniae AP200 9726409 YP_003875989.1 CDS SPAP_0394 NC_014494.1 368252 368848 R Operon 166 Gene 2 COG3331 Penicillin-binding protein-related factor A, putative recombinase; penicillin-binding protein-related factor A, putative recombinase complement(368252..368848) Streptococcus pneumoniae AP200 9726410 YP_003875990.1 CDS SPAP_0395 NC_014494.1 368914 369441 D Operon 167 Gene 1 COG4474 Uncharacterized protein conserved in bacteria; hypothetical protein 368914..369441 Streptococcus pneumoniae AP200 9726411 YP_003875991.1 CDS SPAP_0396 NC_014494.1 369499 369840 D Operon 167 Gene 2 COG3599 Cell division initiation protein; cell division initiation protein 369499..369840 Streptococcus pneumoniae AP200 9726412 YP_003875992.1 CDS SPAP_0397 NC_014494.1 369829 370038 R Operon 168 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(369829..370038) Streptococcus pneumoniae AP200 9726413 YP_003875993.1 CDS SPAP_0398 NC_014494.1 370326 371483 D Operon 169 Gene 1 COG0116 Predicted N6-adenine-specific DNA methylase; putative N6-adenine-specific DNA methylase 370326..371483 Streptococcus pneumoniae AP200 9726414 YP_003875994.1 CDS SPAP_0399 NC_014494.1 371496 372890 D Operon 169 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 371496..372890 Streptococcus pneumoniae AP200 9726415 YP_003875995.1 CDS SPAP_0400 NC_014494.1 372966 374390 D Operon 169 Gene 3 COG0362 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase 372966..374390 Streptococcus pneumoniae AP200 9726416 YP_003875996.1 CDS SPAP_0401 NC_014494.1 374402 375091 D Operon 169 Gene 4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 374402..375091 Streptococcus pneumoniae AP200 9726417 YP_003875997.1 CDS SPAP_0402 NC_014494.1 375189 376208 D Operon 169 Gene 5 COG5263 FOG: Choline binding protein F; choline binding protein F 375189..376208 Streptococcus pneumoniae AP200 9726418 YP_003875998.1 CDS SPAP_0403 NC_014494.1 376326 377582 R Operon 170 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(376326..377582) Streptococcus pneumoniae AP200 9726419 YP_003875999.1 CDS SPAP_0404 NC_014494.1 377717 378187 R Operon 171 Gene 1 COG4403 Lantibiotic modifying enzyme; lantibiotic modifying enzyme complement(377717..378187) Streptococcus pneumoniae AP200 9726420 YP_003876000.1 CDS SPAP_0405 NC_014494.1 378087 378476 R Operon 171 Gene 2 COG4403 Lantibiotic modifying enzyme; lantibiotic modifying enzyme complement(378087..378476) Streptococcus pneumoniae AP200 9726421 YP_003876001.1 CDS SPAP_0406 NC_014494.1 378436 378630 D Operon 172 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 378436..378630 Streptococcus pneumoniae AP200 9726422 YP_003876002.1 CDS SPAP_0407 NC_014494.1 379088 379417 D Operon 173 Gene 1 COG5263 FOG: Choline binding protein C; choline binding protein C 379088..379417 Streptococcus pneumoniae AP200 9726423 YP_003876003.1 CDS SPAP_0408 NC_014494.1 379539 380417 D Operon 174 Gene 1 COG1577 Mevalonate kinase; mevalonate kinase 379539..380417 Streptococcus pneumoniae AP200 9726424 YP_003876004.1 CDS SPAP_0409 NC_014494.1 380399 381352 D Operon 174 Gene 2 COG3407 Mevalonate pyrophosphate decarboxylase; mevalonate pyrophosphate decarboxylase 380399..381352 Streptococcus pneumoniae AP200 9726425 YP_003876005.1 CDS SPAP_0410 NC_014494.1 381339 382346 D Operon 174 Gene 3 COG1577 Mevalonate kinase; mevalonate kinase 381339..382346 Streptococcus pneumoniae AP200 9726426 YP_003876006.1 CDS SPAP_0411 NC_014494.1 382330 383340 D Operon 174 Gene 4 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 382330..383340 Streptococcus pneumoniae AP200 9726427 YP_003876007.1 CDS SPAP_0412 NC_014494.1 383417 384115 D Operon 174 Gene 5 COG4758 Predicted membrane protein; hypothetical protein 383417..384115 Streptococcus pneumoniae AP200 9726428 YP_003876008.1 CDS SPAP_0413 NC_014494.1 384112 385107 D Operon 174 Gene 6 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase 384112..385107 Streptococcus pneumoniae AP200 9726429 YP_003876009.1 CDS SPAP_0414 NC_014494.1 385121 385753 D Operon 174 Gene 7 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; CheY-like receiver/HTH DNA-binding domain-containing response regulator 385121..385753 Streptococcus pneumoniae AP200 9726430 YP_003876010.1 CDS SPAP_0415 NC_014494.1 385754 385963 D Operon 174 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 385754..385963 Streptococcus pneumoniae AP200 9726431 YP_003876011.1 CDS SPAP_0416 NC_014494.1 386346 386522 D Operon 175 Gene 1 COG4912 Predicted DNA alkylation repair enzyme; putative DNA alkylation repair enzyme 386346..386522 Streptococcus pneumoniae AP200 9726432 YP_003876012.1 CDS SPAP_0417 NC_014494.1 386672 387586 D Operon 176 Gene 1 COG3591 V8-like Glu-specific endopeptidase; V8-like Glu-specific endopeptidase 386672..387586 Streptococcus pneumoniae AP200 9726433 YP_003876013.1 CDS SPAP_0418 NC_014494.1 388014 388244 D Operon 177 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 388014..388244 Streptococcus pneumoniae AP200 9726434 YP_003876014.1 CDS SPAP_0419 NC_014494.1 388438 389721 D Operon 178 Gene 1 COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); FKBP-type peptidyl-prolyl cis-trans isomerase 388438..389721 Streptococcus pneumoniae AP200 9726435 YP_003876015.1 CDS SPAP_0420 NC_014494.1 389769 390446 R Operon 179 Gene 1 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha complement(389769..390446) Streptococcus pneumoniae AP200 9726436 YP_003876016.1 CDS SPAP_0421 NC_014494.1 390500 392134 R Operon 179 Gene 2 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha complement(390500..392134) Streptococcus pneumoniae AP200 9726437 YP_003876017.1 CDS SPAP_0422 NC_014494.1 392413 392913 R Operon 180 Gene 1 COG0681 Signal peptidase I; signal peptidase I complement(392413..392913) Streptococcus pneumoniae AP200 9726438 YP_003876018.1 CDS SPAP_0423 NC_014494.1 393031 393912 R Operon 181 Gene 1 COG1039 Ribonuclease HIII; ribonuclease HIII complement(393031..393912) Streptococcus pneumoniae AP200 9726439 YP_003876019.1 CDS SPAP_0424 NC_014494.1 393999 394301 D Operon 182 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 393999..394301 Streptococcus pneumoniae AP200 9726440 YP_003876020.1 CDS SPAP_0425 NC_014494.1 394298 394846 D Operon 182 Gene 2 COG1286 Uncharacterized membrane protein, required for colicin V production; hypothetical protein 394298..394846 Streptococcus pneumoniae AP200 9726441 YP_003876021.1 CDS SPAP_0426 NC_014494.1 394950 397286 D Operon 183 Gene 1 COG1193 Mismatch repair ATPase (MutS family); mismatch repair ATPase 394950..397286 Streptococcus pneumoniae AP200 9726442 YP_003876022.1 CDS SPAP_0427 NC_014494.1 397629 398951 D Operon 184 Gene 1 COG1115 Na+/alanine symporter; Na+/alanine symporter 397629..398951 Streptococcus pneumoniae AP200 9726443 YP_003876023.1 CDS SPAP_0428 NC_014494.1 399169 399717 D Operon 185 Gene 1 COG2128 Uncharacterized conserved protein; hypothetical protein 399169..399717 Streptococcus pneumoniae AP200 9726444 YP_003876024.1 CDS SPAP_0429 NC_014494.1 399827 400726 D Operon 186 Gene 1 COG1275 Tellurite resistance protein and related permeases; tellurite resistance protein-like permease 399827..400726 Streptococcus pneumoniae AP200 9726445 YP_003876025.1 CDS SPAP_0430 NC_014494.1 400751 402025 R Operon 187 Gene 1 COG0172 Seryl-tRNA synthetase; seryl-tRNA synthetase complement(400751..402025) Streptococcus pneumoniae AP200 9726446 YP_003876026.1 CDS SPAP_0431 NC_014494.1 402239 402610 R Operon 188 Gene 1 COG4687 Uncharacterized protein conserved in bacteria; hypothetical protein complement(402239..402610) Streptococcus pneumoniae AP200 9726447 YP_003876027.1 CDS SPAP_0432 NC_014494.1 402613 403977 R Operon 188 Gene 2 COG0527 Aspartokinases; aspartokinase complement(402613..403977) Streptococcus pneumoniae AP200 9726448 YP_003876028.1 CDS SPAP_0433 NC_014494.1 404302 405087 D Operon 189 Gene 1 COG1024 Enoyl-CoA hydratase/carnithine racemase; enoyl-CoA hydratase/carnithine racemase 404302..405087 Streptococcus pneumoniae AP200 9726449 YP_003876029.1 CDS SPAP_0434 NC_014494.1 405181 405615 D Operon 189 Gene 2 COG1846 Transcriptional regulators; transcriptional regulator 405181..405615 Streptococcus pneumoniae AP200 9726450 YP_003876030.1 CDS SPAP_0435 NC_014494.1 405615 406589 D Operon 189 Gene 3 COG0332 3-oxoacyl-[acyl-carrier-protein] synthase III; 3-oxoacyl-ACP synthase 405615..406589 Streptococcus pneumoniae AP200 9726451 YP_003876031.1 CDS SPAP_0436 NC_014494.1 406649 406873 D Operon 189 Gene 4 COG0236 Acyl carrier protein; acyl carrier protein 406649..406873 Streptococcus pneumoniae AP200 9726452 YP_003876032.1 CDS SPAP_0437 NC_014494.1 406992 407966 D Operon 190 Gene 1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase; dioxygenase 406992..407966 Streptococcus pneumoniae AP200 9726453 YP_003876033.1 CDS SPAP_0438 NC_014494.1 407959 408879 D Operon 190 Gene 2 COG0331 (acyl-carrier-protein) S-malonyltransferase; (acyl-carrier-protein) S-malonyltransferase 407959..408879 Streptococcus pneumoniae AP200 9726454 YP_003876034.1 CDS SPAP_0439 NC_014494.1 408913 409644 D Operon 190 Gene 3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); dehydrogenase 408913..409644 Streptococcus pneumoniae AP200 9726455 YP_003876035.1 CDS SPAP_0440 NC_014494.1 409666 410901 D Operon 190 Gene 4 COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; 3-oxoacyl-ACP synthase 409666..410901 Streptococcus pneumoniae AP200 9726456 YP_003876036.1 CDS SPAP_0441 NC_014494.1 410904 411389 D Operon 190 Gene 5 COG0511 Biotin carboxyl carrier protein; biotin carboxyl carrier protein 410904..411389 Streptococcus pneumoniae AP200 9726457 YP_003876037.1 CDS SPAP_0442 NC_014494.1 411386 411808 D Operon 190 Gene 6 COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases; (3R)-hydroxymyristoyl-ACP dehydratase 411386..411808 Streptococcus pneumoniae AP200 9726458 YP_003876038.1 CDS SPAP_0443 NC_014494.1 411820 413187 D Operon 190 Gene 7 COG0439 Biotin carboxylase; biotin carboxylase 411820..413187 Streptococcus pneumoniae AP200 9726459 YP_003876039.1 CDS SPAP_0444 NC_014494.1 413224 414090 D Operon 190 Gene 8 COG0777 Acetyl-CoA carboxylase beta subunit; acetyl-Coa carboxylase subunit beta 413224..414090 Streptococcus pneumoniae AP200 9726460 YP_003876040.1 CDS SPAP_0445 NC_014494.1 414087 414854 D Operon 190 Gene 9 COG0825 Acetyl-CoA carboxylase alpha subunit; acetyl-Coa carboxylase subunit alpha 414087..414854 Streptococcus pneumoniae AP200 9726461 YP_003876041.1 CDS SPAP_0446 NC_014494.1 415013 415198 D Operon 191 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 415013..415198 Streptococcus pneumoniae AP200 9726462 YP_003876042.1 CDS SPAP_0447 NC_014494.1 415216 415689 D Operon 191 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 415216..415689 Streptococcus pneumoniae AP200 9726463 YP_003876043.1 CDS SPAP_0448 NC_014494.1 415988 416410 R Operon 192 Gene 1 COG0781 Transcription termination factor; transcription termination factor complement(415988..416410) Streptococcus pneumoniae AP200 9726464 YP_003876044.1 CDS SPAP_0449 NC_014494.1 416403 416792 R Operon 192 Gene 2 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein complement(416403..416792) Streptococcus pneumoniae AP200 9726465 YP_003876045.1 CDS SPAP_0450 NC_014494.1 416814 417374 R EF-P/eIF-5A; Operon 192 Gene 3 COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); translation elongation factor P / translation initiation factor 5A complement(416814..417374) Streptococcus pneumoniae AP200 9726466 YP_003876046.1 CDS SPAP_0451 NC_014494.1 417503 418945 R Operon 193 Gene 1 COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit B complement(417503..418945) Streptococcus pneumoniae AP200 9726467 YP_003876047.1 CDS SPAP_0452 NC_014494.1 418945 420411 R Operon 193 Gene 2 COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases; Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit A-like amidase complement(418945..420411) Streptococcus pneumoniae AP200 9726468 YP_003876048.1 CDS SPAP_0453 NC_014494.1 420411 420713 R Operon 193 Gene 3 COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; Asp-tRNAAsn/Glu-tRNAGln amidotransferase subunit C complement(420411..420713) Streptococcus pneumoniae AP200 9726469 YP_003876049.1 CDS SPAP_0454 NC_014494.1 420926 422470 D Operon 194 Gene 1 COG4108 Peptide chain release factor RF-3; peptide chain release factor RF-3 420926..422470 Streptococcus pneumoniae AP200 9726470 YP_003876050.1 CDS SPAP_0455 NC_014494.1 422898 423095 D Operon 195 Gene 1 COG1442 Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases; lipopolysaccharide biosynthesis protein 422898..423095 Streptococcus pneumoniae AP200 9726471 YP_003876051.1 CDS SPAP_0456 NC_014494.1 423498 423686 D Operon 196 Gene 1 protein supported gi|15900358|ref|NP_344962.1| 50S ribosomal protein L28; hypothetical protein 423498..423686 Streptococcus pneumoniae AP200 9726472 YP_003876052.1 CDS SPAP_0457 NC_014494.1 423843 424208 D Operon 197 Gene 1 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein 423843..424208 Streptococcus pneumoniae AP200 9726473 YP_003876053.1 CDS SPAP_0458 NC_014494.1 424211 425878 D Operon 197 Gene 2 COG1461 Predicted kinase related to dihydroxyacetone kinase; putative kinase 424211..425878 Streptococcus pneumoniae AP200 9726474 YP_003876054.1 CDS SPAP_0459 NC_014494.1 426078 427778 D acetolactate synthase; pyruvate dehydrogenase (cytochrome); glyoxylate carboligase; l phosphonopyruvate decarboxylase; Operon 198 Gene 1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; thiamine pyrophosphate-requiring enzyme 426078..427778 Streptococcus pneumoniae AP200 9726475 YP_003876055.1 CDS SPAP_0460 NC_014494.1 427771 428247 D Operon 198 Gene 2 COG0440 Acetolactate synthase, small (regulatory) subunit; acetolactate synthase small subunit 427771..428247 Streptococcus pneumoniae AP200 9726476 YP_003876056.1 CDS SPAP_0461 NC_014494.1 428313 429335 D Operon 198 Gene 3 COG0059 Ketol-acid reductoisomerase; ketol-acid reductoisomerase 428313..429335 Streptococcus pneumoniae AP200 9726477 YP_003876057.1 CDS SPAP_0462 NC_014494.1 429538 429678 D Operon 199 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 429538..429678 Streptococcus pneumoniae AP200 9726478 YP_003876058.1 CDS SPAP_0463 NC_014494.1 429916 430272 D Operon 200 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 429916..430272 Streptococcus pneumoniae AP200 9726479 YP_003876059.1 CDS SPAP_0464 NC_014494.1 430322 431572 D Operon 200 Gene 2 COG1171 Threonine dehydratase; threonine dehydratase 430322..431572 Streptococcus pneumoniae AP200 9726480 YP_003876060.1 CDS SPAP_0465 NC_014494.1 432443 432658 D Operon 201 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 432443..432658 Streptococcus pneumoniae AP200 9726481 YP_003876061.1 CDS SPAP_0466 NC_014494.1 432767 433507 R Operon 202 Gene 1 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase complement(432767..433507) Streptococcus pneumoniae AP200 9726482 YP_003876062.1 CDS SPAP_0467 NC_014494.1 433507 435072 R Operon 202 Gene 2 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(433507..435072) Streptococcus pneumoniae AP200 9726483 YP_003876063.1 CDS SPAP_0468 NC_014494.1 435210 437099 D Operon 203 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 435210..437099 Streptococcus pneumoniae AP200 9726484 YP_003876064.1 CDS SPAP_0469 NC_014494.1 437590 438210 R Operon 204 Gene 1 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 complement(437590..438210) Streptococcus pneumoniae AP200 9726485 YP_003876065.1 CDS SPAP_0470 NC_014494.1 438128 438421 R Operon 204 Gene 2 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 complement(438128..438421) Streptococcus pneumoniae AP200 9726486 YP_003876066.1 CDS SPAP_0471 NC_014494.1 438676 439521 D Operon 205 Gene 1 COG1968 Uncharacterized bacitracin resistance protein; hypothetical protein 438676..439521 Streptococcus pneumoniae AP200 9726487 YP_003876067.1 CDS SPAP_0472 NC_014494.1 439668 440729 R Operon 206 Gene 1 COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; nucleotidyltransferase/DnA polymerase involved in DnA repair complement(439668..440729) Streptococcus pneumoniae AP200 9726488 YP_003876068.1 CDS SPAP_0473 NC_014494.1 441077 443401 D Operon 207 Gene 1 COG1882 Pyruvate-formate lyase; pyruvate-formate lyase 441077..443401 Streptococcus pneumoniae AP200 9726489 YP_003876069.1 CDS SPAP_0474 NC_014494.1 443768 443983 R Operon 208 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(443768..443983) Streptococcus pneumoniae AP200 9726490 YP_003876070.1 CDS SPAP_0475 NC_014494.1 444313 444597 R Operon 209 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(444313..444597) Streptococcus pneumoniae AP200 9726491 YP_003876071.1 CDS SPAP_0476 NC_014494.1 445209 445379 R Operon 210 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(445209..445379) Streptococcus pneumoniae AP200 9726492 YP_003876072.1 CDS SPAP_0477 NC_014494.1 446029 447252 R Operon 211 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase complement(446029..447252) Streptococcus pneumoniae AP200 9726493 YP_003876073.1 CDS SPAP_0478 NC_014494.1 447420 448742 D Operon 212 Gene 1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 447420..448742 Streptococcus pneumoniae AP200 9726494 YP_003876074.1 CDS SPAP_0479 NC_014494.1 448744 449217 D Operon 212 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 448744..449217 Streptococcus pneumoniae AP200 9726495 YP_003876075.1 CDS SPAP_0480 NC_014494.1 449235 450632 D Operon 212 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 449235..450632 Streptococcus pneumoniae AP200 9726496 YP_003876076.1 CDS SPAP_0481 NC_014494.1 450800 451144 D Operon 213 Gene 1 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 450800..451144 Streptococcus pneumoniae AP200 9726497 YP_003876077.1 CDS SPAP_0482 NC_014494.1 451154 452566 D Operon 213 Gene 2 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 451154..452566 Streptococcus pneumoniae AP200 9726498 YP_003876078.1 CDS SPAP_0483 NC_014494.1 452636 454312 D Operon 213 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 452636..454312 Streptococcus pneumoniae AP200 9726499 YP_003876079.1 CDS SPAP_0484 NC_014494.1 454438 455865 R Operon 214 Gene 1 COG0168 Trk-type K+ transport systems, membrane components; Trk-type K+ transport systems membrane protein complement(454438..455865) Streptococcus pneumoniae AP200 9726500 YP_003876080.1 CDS SPAP_0485 NC_014494.1 455881 457230 R Operon 214 Gene 2 COG0569 K+ transport systems, NAD-binding component; K+ transport systems NAD-binding component complement(455881..457230) Streptococcus pneumoniae AP200 9726501 YP_003876081.1 CDS SPAP_0486 NC_014494.1 457419 458267 D Operon 215 Gene 1 COG1912 Uncharacterized conserved protein; hypothetical protein 457419..458267 Streptococcus pneumoniae AP200 9726502 YP_003876082.1 CDS SPAP_0487 NC_014494.1 458282 458830 D Operon 215 Gene 2 COG4720 Predicted membrane protein; hypothetical protein 458282..458830 Streptococcus pneumoniae AP200 9726503 YP_003876083.1 CDS SPAP_0488 NC_014494.1 458837 459049 D Operon 215 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 458837..459049 Streptococcus pneumoniae AP200 9726504 YP_003876084.1 CDS SPAP_0489 NC_014494.1 459151 460833 D Operon 216 Gene 1 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 459151..460833 Streptococcus pneumoniae AP200 9726505 YP_003876085.1 CDS SPAP_0490 NC_014494.1 460818 461648 D Operon 216 Gene 2 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter 460818..461648 Streptococcus pneumoniae AP200 9726506 YP_003876086.1 CDS SPAP_0491 NC_014494.1 461841 462344 D Operon 217 Gene 1 COG0219 Predicted rRNA methylase (SpoU class); putative rRNA methylase 461841..462344 Streptococcus pneumoniae AP200 9726507 YP_003876087.1 CDS SPAP_0492 NC_014494.1 462797 463360 D Operon 218 Gene 1 COG3601 Predicted membrane protein; hypothetical protein 462797..463360 Streptococcus pneumoniae AP200 9726508 YP_003876088.1 CDS SPAP_0493 NC_014494.1 463374 464000 D Operon 218 Gene 2 COG0671 Membrane-associated phospholipid phosphatase; membrane-associated phospholipid phosphatase 463374..464000 Streptococcus pneumoniae AP200 9726509 YP_003876089.1 CDS SPAP_0494 NC_014494.1 464028 464417 D Operon 218 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 464028..464417 Streptococcus pneumoniae AP200 9726510 YP_003876090.1 CDS SPAP_0495 NC_014494.1 464422 464871 D Operon 218 Gene 4 COG1247 Sortase and related acyltransferases; sortase-like acyltransferase 464422..464871 Streptococcus pneumoniae AP200 9726511 YP_003876091.1 CDS SPAP_0496 NC_014494.1 464999 465586 D Operon 219 Gene 1 COG3343 DNA-directed RNA polymerase, delta subunit; DNA-directed RNA polymerase subunit delta 464999..465586 Streptococcus pneumoniae AP200 9726512 YP_003876092.1 CDS SPAP_0497 NC_014494.1 465976 467583 D Operon 220 Gene 1 COG0504 CTP synthase (UTP-ammonia lyase); CTP synthase 465976..467583 Streptococcus pneumoniae AP200 9726513 YP_003876093.1 CDS SPAP_0498 NC_014494.1 468142 469773 R Operon 221 Gene 1 COG1283 Na+/phosphate symporter; Na+/phosphate symporter complement(468142..469773) Streptococcus pneumoniae AP200 9726514 YP_003876094.1 CDS SPAP_0499 NC_014494.1 469975 470085 D Operon 222 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 469975..470085 Streptococcus pneumoniae AP200 9726515 YP_003876095.1 CDS SPAP_0500 NC_014494.1 470066 475006 D Operon 222 Gene 2 COG4724 Endo-beta-N-acetylglucosaminidase D; endo-beta-N-acetylglucosaminidase D 470066..475006 Streptococcus pneumoniae AP200 9726516 YP_003876096.1 CDS SPAP_0501 NC_014494.1 475096 476292 D Operon 222 Gene 3 COG0126 3-phosphoglycerate kinase; 3-phosphoglycerate kinase 475096..476292 Streptococcus pneumoniae AP200 9726517 YP_003876097.1 CDS SPAP_0502 NC_014494.1 476428 476955 D Operon 223 Gene 1 COG4129 Predicted membrane protein; hypothetical protein 476428..476955 Streptococcus pneumoniae AP200 9726518 YP_003876098.1 CDS SPAP_0503 NC_014494.1 477032 477388 D Operon 223 Gene 2 COG0789 Predicted transcriptional regulators; putative transcriptional regulator 477032..477388 Streptococcus pneumoniae AP200 9726519 YP_003876099.1 CDS SPAP_0504 NC_014494.1 477425 478771 D Operon 223 Gene 3 COG0174 Glutamine synthetase; glutamine synthetase 477425..478771 Streptococcus pneumoniae AP200 9726520 YP_003876100.1 CDS SPAP_0505 NC_014494.1 478951 479100 D Operon 224 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 478951..479100 Streptococcus pneumoniae AP200 9726521 YP_003876101.1 CDS SPAP_0506 NC_014494.1 479800 480693 D Operon 225 Gene 1 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 479800..480693 Streptococcus pneumoniae AP200 9726522 YP_003876102.1 CDS SPAP_0507 NC_014494.1 480789 481295 R Operon 226 Gene 1 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit complement(480789..481295) Streptococcus pneumoniae AP200 9726523 YP_003876103.1 CDS SPAP_0508 NC_014494.1 481405 482202 R Operon 227 Gene 1 COG0582 Integrase; integrase complement(481405..482202) Streptococcus pneumoniae AP200 9726524 YP_003876104.1 CDS SPAP_0509 NC_014494.1 482259 482981 R Operon 227 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit complement(482259..482981) Streptococcus pneumoniae AP200 9726525 YP_003876105.1 CDS SPAP_0510 NC_014494.1 483077 483826 R Operon 227 Gene 3 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit complement(483077..483826) Streptococcus pneumoniae AP200 9726526 YP_003876106.1 CDS SPAP_0511 NC_014494.1 483826 485289 R Operon 227 Gene 4 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit complement(483826..485289) Streptococcus pneumoniae AP200 9726527 YP_003876107.1 CDS SPAP_0512 NC_014494.1 485302 487635 R Operon 227 Gene 5 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I site-specific restriction-modification system protein R complement(485302..487635) Streptococcus pneumoniae AP200 9726528 YP_003876108.1 CDS SPAP_0513 NC_014494.1 488242 488751 D Operon 228 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 488242..488751 Streptococcus pneumoniae AP200 9726529 YP_003876109.1 CDS SPAP_0514 NC_014494.1 488915 489949 D Operon 229 Gene 1 COG1420 Transcriptional regulator of heat shock gene; heat shock proteins transcriptional regulator 488915..489949 Streptococcus pneumoniae AP200 9726530 YP_003876110.1 CDS SPAP_0515 NC_014494.1 489976 490500 D Operon 229 Gene 2 COG0576 Molecular chaperone GrpE (heat shock protein); molecular chaperone GrpE 489976..490500 Streptococcus pneumoniae AP200 9726531 YP_003876111.1 CDS SPAP_0516 NC_014494.1 490980 492803 D Operon 229 Gene 3 COG0443 Molecular chaperone; molecular chaperone 490980..492803 Streptococcus pneumoniae AP200 9726532 YP_003876112.1 CDS SPAP_0517 NC_014494.1 493562 494698 D Operon 230 Gene 1 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; DnaJ-class molecular chaperone with C-terminal Zn finger domain 493562..494698 Streptococcus pneumoniae AP200 9726533 YP_003876113.1 CDS SPAP_0518 NC_014494.1 494727 494903 R Operon 231 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(494727..494903) Streptococcus pneumoniae AP200 9726534 YP_003876114.1 CDS SPAP_0519 NC_014494.1 495065 495352 R Operon 232 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(495065..495352) Streptococcus pneumoniae AP200 9726535 YP_003876115.1 CDS SPAP_0520 NC_014494.1 495362 495772 R Operon 232 Gene 2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase complement(495362..495772) Streptococcus pneumoniae AP200 9726536 YP_003876116.1 CDS SPAP_0521 NC_014494.1 495840 496571 D Operon 233 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 495840..496571 Streptococcus pneumoniae AP200 9726537 YP_003876117.1 CDS SPAP_0522 NC_014494.1 496568 497617 D Operon 233 Gene 2 COG4473 Predicted ABC-type exoprotein transport system, permease component; putative exoprotein ABC transporter permease 496568..497617 Streptococcus pneumoniae AP200 9726538 YP_003876118.1 CDS SPAP_0523 NC_014494.1 497785 498114 R Operon 234 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(497785..498114) Streptococcus pneumoniae AP200 9726539 YP_003876119.1 CDS SPAP_0524 NC_014494.1 498391 498729 D Operon 235 Gene 1 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 498391..498729 Streptococcus pneumoniae AP200 9726540 YP_003876120.1 CDS SPAP_0525 NC_014494.1 498734 499471 D Operon 235 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator 498734..499471 Streptococcus pneumoniae AP200 9726541 YP_003876121.1 CDS SPAP_0526 NC_014494.1 499485 500825 D Operon 235 Gene 3 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 499485..500825 Streptococcus pneumoniae AP200 9726542 YP_003876122.1 CDS SPAP_0527 NC_014494.1 500869 501024 R Operon 236 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(500869..501024) Streptococcus pneumoniae AP200 9726543 YP_003876123.1 CDS SPAP_0528 NC_014494.1 501081 502442 R Operon 236 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(501081..502442) Streptococcus pneumoniae AP200 9726544 YP_003876124.1 CDS SPAP_0529 NC_014494.1 502453 504606 R Operon 236 Gene 3 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter complement(502453..504606) Streptococcus pneumoniae AP200 9726545 YP_003876125.1 CDS SPAP_0530 NC_014494.1 504888 505142 D Operon 237 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 504888..505142 Streptococcus pneumoniae AP200 9726546 YP_003876126.1 CDS SPAP_0531 NC_014494.1 505158 505361 D Operon 237 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 505158..505361 Streptococcus pneumoniae AP200 9726547 YP_003876127.1 CDS SPAP_0532 NC_014494.1 505380 505589 D Operon 237 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 505380..505589 Streptococcus pneumoniae AP200 9726548 YP_003876128.1 CDS SPAP_0533 NC_014494.1 505605 505754 D Operon 237 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 505605..505754 Streptococcus pneumoniae AP200 9726549 YP_003876129.1 CDS SPAP_0534 NC_014494.1 506274 506435 D Operon 238 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 506274..506435 Streptococcus pneumoniae AP200 9726550 YP_003876130.1 CDS SPAP_0535 NC_014494.1 506445 506816 D Operon 238 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 506445..506816 Streptococcus pneumoniae AP200 9726551 YP_003876131.1 CDS SPAP_0536 NC_014494.1 506939 507142 R Operon 239 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(506939..507142) Streptococcus pneumoniae AP200 9726552 YP_003876132.1 CDS SPAP_0537 NC_014494.1 507178 507345 D Operon 240 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 507178..507345 Streptococcus pneumoniae AP200 9726553 YP_003876133.1 CDS SPAP_0538 NC_014494.1 507445 507828 D Operon 240 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 507445..507828 Streptococcus pneumoniae AP200 9726554 YP_003876134.1 CDS SPAP_0539 NC_014494.1 507880 508569 D Operon 240 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 507880..508569 Streptococcus pneumoniae AP200 9726555 YP_003876135.1 CDS SPAP_0540 NC_014494.1 508611 508859 D Operon 240 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 508611..508859 Streptococcus pneumoniae AP200 9726556 YP_003876136.1 CDS SPAP_0541 NC_014494.1 508889 509500 D Operon 240 Gene 5 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 508889..509500 Streptococcus pneumoniae AP200 9726557 YP_003876137.1 CDS SPAP_0542 NC_014494.1 509662 510456 D Operon 241 Gene 1 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative choline kinase 509662..510456 Streptococcus pneumoniae AP200 9726558 YP_003876138.1 CDS SPAP_0543 NC_014494.1 510453 511088 D Operon 241 Gene 2 COG0220 Predicted S-adenosylmethionine-dependent methyltransferase; putative S-adenosylmethionine-dependent methyltransferase 510453..511088 Streptococcus pneumoniae AP200 9726559 YP_003876139.1 CDS SPAP_0544 NC_014494.1 511289 511693 D Operon 242 Gene 1 COG0779 Uncharacterized protein conserved in bacteria; hypothetical protein 511289..511693 Streptococcus pneumoniae AP200 9726560 YP_003876140.1 CDS SPAP_0545 NC_014494.1 511749 512873 D Operon 242 Gene 2 COG0195 Transcription elongation factor; transcription elongation factor 511749..512873 Streptococcus pneumoniae AP200 9726561 YP_003876141.1 CDS SPAP_0546 NC_014494.1 512895 513188 D Operon 242 Gene 3 COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination; putative nucleic-acid-binding protein implicated in transcription termination 512895..513188 Streptococcus pneumoniae AP200 9726562 YP_003876142.1 CDS SPAP_0547 NC_014494.1 513181 513480 D Operon 242 Gene 4 protein supported gi|15900467|ref|NP_345071.1| hypothetical protein SP_0555; hypothetical protein 513181..513480 Streptococcus pneumoniae AP200 9726563 YP_003876143.1 CDS SPAP_0548 NC_014494.1 513497 516289 D Operon 242 Gene 5 COG0532 Translation initiation factor 2 (IF-2; GTPase); translation initiation factor 2 513497..516289 Streptococcus pneumoniae AP200 9726564 YP_003876144.1 CDS SPAP_0549 NC_014494.1 516540 516890 D Operon 242 Gene 6 COG0858 Ribosome-binding factor A; ribosome-binding factor A 516540..516890 Streptococcus pneumoniae AP200 9726565 YP_003876145.1 CDS SPAP_0550 NC_014494.1 517169 517948 D Operon 243 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 517169..517948 Streptococcus pneumoniae AP200 9726566 YP_003876146.1 CDS SPAP_0551 NC_014494.1 517950 518132 D Operon 243 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 517950..518132 Streptococcus pneumoniae AP200 9726567 YP_003876147.1 CDS SPAP_0552 NC_014494.1 518637 518870 D Operon 244 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 518637..518870 Streptococcus pneumoniae AP200 9726568 YP_003876148.1 CDS SPAP_0553 NC_014494.1 518870 520204 D Operon 244 Gene 2 COG2461 Uncharacterized conserved protein; hypothetical protein 518870..520204 Streptococcus pneumoniae AP200 9726569 YP_003876149.1 CDS SPAP_0554 NC_014494.1 520214 520468 D Operon 244 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 520214..520468 Streptococcus pneumoniae AP200 9726570 YP_003876150.1 CDS SPAP_0555 NC_014494.1 520564 520959 D Operon 244 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 520564..520959 Streptococcus pneumoniae AP200 9726571 YP_003876151.1 CDS SPAP_0556 NC_014494.1 521371 521820 D Operon 245 Gene 1 COG1853 Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family; hypothetical protein 521371..521820 Streptococcus pneumoniae AP200 9726572 YP_003876152.1 CDS SPAP_0557 NC_014494.1 521807 522367 D Operon 245 Gene 2 protein supported gi|125718620|ref|YP_001035753.1| ribosomal protein N-acetylase; hypothetical protein 521807..522367 Streptococcus pneumoniae AP200 9726573 YP_003876153.1 CDS SPAP_0558 NC_014494.1 522367 522945 D Operon 245 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 522367..522945 Streptococcus pneumoniae AP200 9726574 YP_003876154.1 CDS SPAP_0559 NC_014494.1 522938 525589 D Operon 245 Gene 4 COG0525 Valyl-tRNA synthetase; Valyl-tRNA synthetase 522938..525589 Streptococcus pneumoniae AP200 9726575 YP_003876155.1 CDS SPAP_0560 NC_014494.1 525660 526415 D Operon 245 Gene 5 COG5048 FOG: Zn-finger; Zn-finger 525660..526415 Streptococcus pneumoniae AP200 9726576 YP_003876156.1 CDS SPAP_0561 NC_014494.1 526700 526801 D Operon 246 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 526700..526801 Streptococcus pneumoniae AP200 9726577 YP_003876157.1 CDS SPAP_0562 NC_014494.1 526925 527794 D Operon 247 Gene 1 COG4951 Uncharacterized protein conserved in bacteria; hypothetical protein 526925..527794 Streptococcus pneumoniae AP200 9726578 YP_003876158.1 CDS SPAP_0563 NC_014494.1 527808 528185 R Operon 248 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 complement(527808..528185) Streptococcus pneumoniae AP200 9726579 YP_003876159.1 CDS SPAP_0564 NC_014494.1 528198 528623 R transposase-like protein, IS1515 complement(528198..528623) Streptococcus pneumoniae AP200 9726580 YP_003876160.1 CDS SPAP_0565 NC_014494.1 528798 528944 D Operon 249 Gene 1 COG1061 DNA or RNA helicases of superfamily II; DNA or RNA helicases of superfamily II 528798..528944 Streptococcus pneumoniae AP200 9726581 YP_003876161.1 CDS SPAP_0566 NC_014494.1 529040 530356 D Operon 249 Gene 2 COG1061 DNA or RNA helicases of superfamily II; DNA or RNA helicases of superfamily II 529040..530356 Streptococcus pneumoniae AP200 9726582 YP_003876162.1 CDS SPAP_0567 NC_014494.1 530656 531495 D Operon 250 Gene 1 COG3711 Transcriptional antiterminator; transcriptional antiterminator 530656..531495 Streptococcus pneumoniae AP200 9726583 YP_003876163.1 CDS SPAP_0568 NC_014494.1 531513 533351 D Operon 250 Gene 2 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 531513..533351 Streptococcus pneumoniae AP200 9726584 YP_003876164.1 CDS SPAP_0569 NC_014494.1 533364 534779 D Operon 250 Gene 3 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 533364..534779 Streptococcus pneumoniae AP200 9726585 YP_003876165.1 CDS SPAP_0570 NC_014494.1 535325 536413 D Operon 251 Gene 1 COG0016 Phenylalanyl-tRNA synthetase alpha subunit; phenylalanyl-tRNA synthetase subunit alpha 535325..536413 Streptococcus pneumoniae AP200 9726586 YP_003876166.1 CDS SPAP_0571 NC_014494.1 536413 536922 D Operon 251 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 536413..536922 Streptococcus pneumoniae AP200 9726587 YP_003876167.1 CDS SPAP_0572 NC_014494.1 536999 539404 D Operon 251 Gene 3 COG0072 Phenylalanyl-tRNA synthetase beta subunit; phenylalanyl-tRNA synthetase subunit beta 536999..539404 Streptococcus pneumoniae AP200 9726588 YP_003876168.1 CDS SPAP_0573 NC_014494.1 539472 540473 R Operon 252 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(539472..540473) Streptococcus pneumoniae AP200 9726589 YP_003876169.1 CDS SPAP_0574 NC_014494.1 540629 540853 D transposase-like protein, IS1239 540629..540853 Streptococcus pneumoniae AP200 9726590 YP_003876170.1 CDS SPAP_0575 NC_014494.1 540907 541035 D Operon 253 Gene 2 COG2826 Transposase and inactivated derivatives, IS30 family; transposase-like protein, IS30 family 540907..541035 Streptococcus pneumoniae AP200 9726591 YP_003876171.1 CDS SPAP_0576 NC_014494.1 541227 541424 D Operon 254 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 541227..541424 Streptococcus pneumoniae AP200 9726592 YP_003876172.1 CDS SPAP_0577 NC_014494.1 541685 543934 D Operon 255 Gene 1 COG0620 Methionine synthase II (cobalamin-independent); methionine synthase II 541685..543934 Streptococcus pneumoniae AP200 9726593 YP_003876173.1 CDS SPAP_0578 NC_014494.1 543998 544864 D Operon 255 Gene 2 COG0685 5,10-methylenetetrahydrofolate reductase; 5,10-methylenetetrahydrofolate reductase 543998..544864 Streptococcus pneumoniae AP200 9726594 YP_003876174.1 CDS SPAP_0579 NC_014494.1 545549 547762 D Operon 256 Gene 1 protein supported gi|62291006|ref|YP_222799.1| polynucleotide phosphorylase/polyadenylase; hypothetical protein 545549..547762 Streptococcus pneumoniae AP200 9726595 YP_003876175.1 CDS SPAP_0580 NC_014494.1 547778 548395 D Operon 256 Gene 2 COG1045 Serine acetyltransferase; serine acetyltransferase 547778..548395 Streptococcus pneumoniae AP200 9726596 YP_003876176.1 CDS SPAP_0581 NC_014494.1 548407 549291 D Operon 256 Gene 3 COG0456 Acetyltransferases; acetyltransferase 548407..549291 Streptococcus pneumoniae AP200 9726597 YP_003876177.1 CDS SPAP_0582 NC_014494.1 549394 550716 D Operon 257 Gene 1 COG0215 Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 549394..550716 Streptococcus pneumoniae AP200 9726598 YP_003876178.1 CDS SPAP_0583 NC_014494.1 550709 551095 D Operon 257 Gene 2 protein supported gi|163764762|ref|ZP_02171816.1| ribosomal protein S13; hypothetical protein 550709..551095 Streptococcus pneumoniae AP200 9726599 YP_003876179.1 CDS SPAP_0584 NC_014494.1 551099 551983 D Operon 257 Gene 3 COG2508 Regulator of polyketide synthase expression; Regulator of polyketide synthase expression 551099..551983 Streptococcus pneumoniae AP200 9726600 YP_003876180.1 CDS SPAP_0585 NC_014494.1 552225 552824 D Operon 258 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 552225..552824 Streptococcus pneumoniae AP200 9726601 YP_003876181.1 CDS SPAP_0586 NC_014494.1 552970 553143 D Operon 259 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 552970..553143 Streptococcus pneumoniae AP200 9726602 YP_003876182.1 CDS SPAP_0587 NC_014494.1 553494 554771 D Operon 260 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 553494..554771 Streptococcus pneumoniae AP200 9726603 YP_003876183.1 CDS SPAP_0588 NC_014494.1 554784 555431 D Operon 260 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 554784..555431 Streptococcus pneumoniae AP200 9726604 YP_003876184.1 CDS SPAP_0589 NC_014494.1 555483 556862 D Operon 260 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 555483..556862 Streptococcus pneumoniae AP200 9726605 YP_003876185.1 CDS SPAP_0590 NC_014494.1 557174 557830 D Operon 261 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 557174..557830 Streptococcus pneumoniae AP200 9726606 YP_003876186.1 CDS SPAP_0591 NC_014494.1 557827 559155 D Operon 261 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 557827..559155 Streptococcus pneumoniae AP200 9726607 YP_003876187.1 CDS SPAP_0592 NC_014494.1 559296 560177 D Operon 262 Gene 1 COG0191 Fructose/tagatose bisphosphate aldolase; fructose/tagatose bisphosphate aldolase 559296..560177 Streptococcus pneumoniae AP200 9726608 YP_003876188.1 CDS SPAP_0593 NC_014494.1 560498 561688 R Operon 263 Gene 1 COG4097 Predicted ferric reductase; putative ferric reductase complement(560498..561688) Streptococcus pneumoniae AP200 9726609 YP_003876189.1 CDS SPAP_0594 NC_014494.1 561946 562605 R Operon 264 Gene 1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(561946..562605) Streptococcus pneumoniae AP200 9726610 YP_003876190.1 CDS SPAP_0595 NC_014494.1 562615 563292 R Operon 264 Gene 2 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(562615..563292) Streptococcus pneumoniae AP200 9726611 YP_003876191.1 CDS SPAP_0596 NC_014494.1 563305 564099 R Operon 264 Gene 3 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(563305..564099) Streptococcus pneumoniae AP200 9726612 YP_003876192.1 CDS SPAP_0597 NC_014494.1 564110 564868 R Operon 264 Gene 4 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase complement(564110..564868) Streptococcus pneumoniae AP200 9726613 YP_003876193.1 CDS SPAP_0598 NC_014494.1 565133 567367 D Operon 265 Gene 1 COG0608 Single-stranded DNA-specific exonuclease; single-stranded DNA-specific exonuclease 565133..567367 Streptococcus pneumoniae AP200 9726614 YP_003876194.1 CDS SPAP_0599 NC_014494.1 567542 569203 D Operon 266 Gene 1 COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; putative metallo-beta-lactamase superfamily hydrolase 567542..569203 Streptococcus pneumoniae AP200 9726615 YP_003876195.1 CDS SPAP_0600 NC_014494.1 569272 570051 D Operon 266 Gene 2 COG0627 Predicted esterase; putative esterase 569272..570051 Streptococcus pneumoniae AP200 9726616 YP_003876196.1 CDS SPAP_0601 NC_014494.1 570163 571383 D Operon 267 Gene 1 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 570163..571383 Streptococcus pneumoniae AP200 9726617 YP_003876197.1 CDS SPAP_0602 NC_014494.1 571388 572620 D Operon 267 Gene 2 COG2348 Uncharacterized protein involved in methicillin resistance; hypothetical protein 571388..572620 Streptococcus pneumoniae AP200 9726618 YP_003876198.1 CDS SPAP_0603 NC_014494.1 572699 573400 D Operon 267 Gene 3 COG5549 Predicted Zn-dependent protease; putative Zn-dependent protease 572699..573400 Streptococcus pneumoniae AP200 9726619 YP_003876199.1 CDS SPAP_0604 NC_014494.1 573439 575286 D Operon 267 Gene 4 COG0322 Nuclease subunit of the excinuclease complex; nuclease subunit of the excinuclease complex 573439..575286 Streptococcus pneumoniae AP200 9726620 YP_003876200.1 CDS SPAP_0605 NC_014494.1 575276 576109 D Operon 267 Gene 5 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase 575276..576109 Streptococcus pneumoniae AP200 9726621 YP_003876201.1 CDS SPAP_0606 NC_014494.1 576291 577091 R Operon 268 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(576291..577091) Streptococcus pneumoniae AP200 9726622 YP_003876202.1 CDS SPAP_0607 NC_014494.1 577165 577275 D Operon 269 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 577165..577275 Streptococcus pneumoniae AP200 9726623 YP_003876203.1 CDS SPAP_0608 NC_014494.1 577262 577867 D Operon 269 Gene 2 COG0778 Nitroreductase; nitroreductase 577262..577867 Streptococcus pneumoniae AP200 9726624 YP_003876204.1 CDS SPAP_0609 NC_014494.1 577880 579280 D Operon 269 Gene 3 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 577880..579280 Streptococcus pneumoniae AP200 9726625 YP_003876205.1 CDS SPAP_0610 NC_014494.1 579334 579912 D Operon 269 Gene 4 protein supported gi|148988990|ref|ZP_01820390.1| hypothetical protein CGSSp6BS73_02415; hypothetical protein 579334..579912 Streptococcus pneumoniae AP200 9726626 YP_003876206.1 CDS SPAP_0611 NC_014494.1 580072 580224 D Operon 270 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 580072..580224 Streptococcus pneumoniae AP200 9726627 YP_003876207.1 CDS SPAP_0612 NC_014494.1 580530 581855 D Operon 271 Gene 1 COG1114 Branched-chain amino acid permeases; branched-chain amino acid permease 580530..581855 Streptococcus pneumoniae AP200 9726628 YP_003876208.1 CDS SPAP_0613 NC_014494.1 581953 582990 D Operon 272 Gene 1 COG1363 Cellulase M and related proteins; cellulase M-like proteins 581953..582990 Streptococcus pneumoniae AP200 9726629 YP_003876209.1 CDS SPAP_0614 NC_014494.1 582992 583453 D Operon 272 Gene 2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases; diadenosine tetraphosphate (Ap4A) hydrolase-like HIT family hydrolase 582992..583453 Streptococcus pneumoniae AP200 9726630 YP_003876210.1 CDS SPAP_0615 NC_014494.1 583479 584195 D Operon 272 Gene 3 COG1876 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase 583479..584195 Streptococcus pneumoniae AP200 9726631 YP_003876211.1 CDS SPAP_0616 NC_014494.1 584504 584929 D Operon 273 Gene 1 protein supported gi|15900537|ref|NP_345141.1| 50S ribosomal protein L11; 50S ribosomal protein L11 584504..584929 Streptococcus pneumoniae AP200 9726632 YP_003876212.1 CDS SPAP_0617 NC_014494.1 585137 585826 D Operon 273 Gene 2 protein supported gi|15900538|ref|NP_345142.1| 50S ribosomal protein L1; hypothetical protein 585137..585826 Streptococcus pneumoniae AP200 9726633 YP_003876213.1 CDS SPAP_0618 NC_014494.1 585915 586301 R Operon 274 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(585915..586301) Streptococcus pneumoniae AP200 9726634 YP_003876214.1 CDS SPAP_0619 NC_014494.1 586438 587220 R Operon 275 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(586438..587220) Streptococcus pneumoniae AP200 9726635 YP_003876215.1 CDS SPAP_0620 NC_014494.1 587944 588306 D Operon 276 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 587944..588306 Streptococcus pneumoniae AP200 9726636 YP_003876216.1 CDS SPAP_0621 NC_014494.1 588705 588950 D Operon 277 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 588705..588950 Streptococcus pneumoniae AP200 9726637 YP_003876217.1 CDS SPAP_0622 NC_014494.1 588878 589036 R Operon 278 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(588878..589036) Streptococcus pneumoniae AP200 9726638 YP_003876218.1 CDS SPAP_0623 NC_014494.1 589351 590343 D Operon 279 Gene 1 COG4586 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase 589351..590343 Streptococcus pneumoniae AP200 9726639 YP_003876219.1 CDS SPAP_0624 NC_014494.1 590345 591163 D Operon 279 Gene 2 COG4587 ABC-type uncharacterized transport system, permease component; ABC transporter permease 590345..591163 Streptococcus pneumoniae AP200 9726640 YP_003876220.1 CDS SPAP_0625 NC_014494.1 591165 591950 D Operon 279 Gene 3 COG3694 ABC-type uncharacterized transport system, permease component; ABC transporter permease 591165..591950 Streptococcus pneumoniae AP200 9726641 YP_003876221.1 CDS SPAP_0626 NC_014494.1 591989 592093 D Operon 279 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 591989..592093 Streptococcus pneumoniae AP200 9726642 YP_003876222.1 CDS SPAP_0627 NC_014494.1 592252 592449 D Operon 280 Gene 1 COG0456 Acetyltransferases; acetyltransferase 592252..592449 Streptococcus pneumoniae AP200 9726643 YP_003876223.1 CDS SPAP_0628 NC_014494.1 592725 592949 R Operon 281 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(592725..592949) Streptococcus pneumoniae AP200 9726644 YP_003876224.1 CDS SPAP_0629 NC_014494.1 593182 593457 D Operon 282 Gene 1 protein supported gi|148984022|ref|ZP_01817341.1| 50S ribosomal protein L1; hypothetical protein 593182..593457 Streptococcus pneumoniae AP200 9726645 YP_003876225.1 CDS SPAP_0630 NC_014494.1 593771 599614 D Operon 282 Gene 2 protein supported gi|148984022|ref|ZP_01817341.1| 50S ribosomal protein L1; hypothetical protein 593771..599614 Streptococcus pneumoniae AP200 9726646 YP_003876226.1 CDS SPAP_0631 NC_014494.1 600241 600717 D Operon 283 Gene 1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein 600241..600717 Streptococcus pneumoniae AP200 9726647 YP_003876227.1 CDS SPAP_0632 NC_014494.1 600755 601003 D Operon 283 Gene 2 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB 600755..601003 Streptococcus pneumoniae AP200 9726648 YP_003876228.1 CDS SPAP_0633 NC_014494.1 601107 602582 D Operon 283 Gene 3 COG3775 Phosphotransferase system, galactitol-specific IIC component; PTS system galactitol-specific transporter subunit IIC 601107..602582 Streptococcus pneumoniae AP200 9726649 YP_003876229.1 CDS SPAP_0634 NC_014494.1 602608 602799 D Operon 283 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 602608..602799 Streptococcus pneumoniae AP200 9726650 YP_003876230.1 CDS SPAP_0635 NC_014494.1 602887 609588 D Operon 283 Gene 5 COG3250 Beta-galactosidase/beta-glucuronidase; beta-galactosidase/beta-glucuronidase 602887..609588 Streptococcus pneumoniae AP200 9726651 YP_003876231.1 CDS SPAP_0636 NC_014494.1 609898 610452 R Operon 284 Gene 1 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_2 complement(609898..610452) Streptococcus pneumoniae AP200 9726652 YP_003876232.1 CDS SPAP_0637 NC_014494.1 610440 610685 R Operon 284 Gene 2 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_2 complement(610440..610685) Streptococcus pneumoniae AP200 9726653 YP_003876233.1 CDS SPAP_0638 NC_014494.1 610643 610846 R Operon 284 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(610643..610846) Streptococcus pneumoniae AP200 9726654 YP_003876234.1 CDS SPAP_0639 NC_014494.1 611024 612367 R transposase-like protein, IS1380 ISSpn5 complement(611024..612367) Streptococcus pneumoniae AP200 9726655 YP_003876235.1 CDS SPAP_0640 NC_014494.1 612602 612946 R Operon 286 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(612602..612946) Streptococcus pneumoniae AP200 9726656 YP_003876236.1 CDS SPAP_0641 NC_014494.1 613062 613562 D Operon 287 Gene 1 COG1242 Predicted Fe-S oxidoreductase; putative Fe-S oxidoreductase 613062..613562 Streptococcus pneumoniae AP200 9726657 YP_003876237.1 CDS SPAP_0642 NC_014494.1 613563 614009 D Operon 287 Gene 2 COG1242 Predicted Fe-S oxidoreductase; putative Fe-S oxidoreductase 613563..614009 Streptococcus pneumoniae AP200 9726658 YP_003876238.1 CDS SPAP_0643 NC_014494.1 613993 614550 D Operon 287 Gene 3 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 613993..614550 Streptococcus pneumoniae AP200 9726659 YP_003876239.1 CDS SPAP_0644 NC_014494.1 614543 614797 D Operon 287 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 614543..614797 Streptococcus pneumoniae AP200 9726660 YP_003876240.1 CDS SPAP_0645 NC_014494.1 614809 616863 D Operon 287 Gene 5 COG0025 NhaP-type Na+/H+ and K+/H+ antiporters; NhaP-type Na+/H+ and K+/H+ antiporter 614809..616863 Streptococcus pneumoniae AP200 9726661 YP_003876241.1 CDS SPAP_0646 NC_014494.1 617047 617907 D Operon 288 Gene 1 COG1295 Predicted membrane protein; hypothetical protein 617047..617907 Streptococcus pneumoniae AP200 9726662 YP_003876242.1 CDS SPAP_0647 NC_014494.1 618118 618828 D Operon 289 Gene 1 COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 618118..618828 Streptococcus pneumoniae AP200 9726663 YP_003876243.1 CDS SPAP_0648 NC_014494.1 618848 619414 D Operon 289 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 618848..619414 Streptococcus pneumoniae AP200 9726664 YP_003876244.1 CDS SPAP_0649 NC_014494.1 619425 620537 D Operon 289 Gene 3 COG0225 Peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase 619425..620537 Streptococcus pneumoniae AP200 9726665 YP_003876245.1 CDS SPAP_0650 NC_014494.1 620805 621542 D Operon 290 Gene 1 COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; CheY-like receiver/AraC DNA-binding domain-containing response regulator 620805..621542 Streptococcus pneumoniae AP200 9726666 YP_003876246.1 CDS SPAP_0651 NC_014494.1 621539 623230 D Operon 290 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein 621539..623230 Streptococcus pneumoniae AP200 9726667 YP_003876247.1 CDS SPAP_0652 NC_014494.1 623346 623909 D Operon 291 Gene 1 COG4475 Uncharacterized protein conserved in bacteria; hypothetical protein 623346..623909 Streptococcus pneumoniae AP200 9726668 YP_003876248.1 CDS SPAP_0653 NC_014494.1 623931 629594 D zinc metalloprotease ZmpB; hypothetical protein 623931..629594 Streptococcus pneumoniae AP200 9726669 YP_003876249.1 CDS SPAP_0654 NC_014494.1 629663 631384 D Operon 292 Gene 1 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate/para-aminobenzoate synthases component I 629663..631384 Streptococcus pneumoniae AP200 9726670 YP_003876250.1 CDS SPAP_0655 NC_014494.1 631385 632002 D Operon 292 Gene 2 COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily); putative alpha/beta superfamily hydrolase 631385..632002 Streptococcus pneumoniae AP200 9726671 YP_003876251.1 CDS SPAP_0656 NC_014494.1 632052 633050 D Operon 292 Gene 3 COG5263 FOG: Choline binding protein; choline binding protein 632052..633050 Streptococcus pneumoniae AP200 9726672 YP_003876252.1 CDS SPAP_0657 NC_014494.1 633177 634136 D Operon 293 Gene 1 protein supported gi|116517028|ref|YP_816079.1| glucokinase; hypothetical protein 633177..634136 Streptococcus pneumoniae AP200 9726673 YP_003876253.1 CDS SPAP_0658 NC_014494.1 634233 635072 D Operon 293 Gene 2 COG0207 Thymidylate synthase; thymidylate synthase 634233..635072 Streptococcus pneumoniae AP200 9726674 YP_003876254.1 CDS SPAP_0659 NC_014494.1 635120 635290 R Operon 294 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(635120..635290) Streptococcus pneumoniae AP200 9726675 YP_003876255.1 CDS SPAP_0660 NC_014494.1 635387 636295 D Operon 295 Gene 1 COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA delta(2)-isopentenylpyrophosphate transferase 635387..636295 Streptococcus pneumoniae AP200 9726676 YP_003876256.1 CDS SPAP_0661 NC_014494.1 636288 637526 D Operon 295 Gene 2 COG2262 GTPases; GTPase 636288..637526 Streptococcus pneumoniae AP200 9726677 YP_003876257.1 CDS SPAP_0662 NC_014494.1 637519 638142 D Operon 295 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 637519..638142 Streptococcus pneumoniae AP200 9726678 YP_003876258.1 CDS SPAP_0663 NC_014494.1 638157 639086 D Operon 295 Gene 4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; metal-dependent hydrolases of the beta-lactamase superfamily III 638157..639086 Streptococcus pneumoniae AP200 9726679 YP_003876259.1 CDS SPAP_0664 NC_014494.1 639107 639862 D Operon 295 Gene 5 COG0300 Short-chain dehydrogenases of various substrate specificities; short-chain dehydrogenase of various substrate specificities 639107..639862 Streptococcus pneumoniae AP200 9726680 YP_003876260.1 CDS SPAP_0665 NC_014494.1 639916 640884 R Operon 296 Gene 1 COG0583 Transcriptional regulator; transcriptional regulator complement(639916..640884) Streptococcus pneumoniae AP200 9726681 YP_003876261.1 CDS SPAP_0666 NC_014494.1 640888 641157 D Operon 297 Gene 1 COG4483 Uncharacterized protein conserved in bacteria; hypothetical protein 640888..641157 Streptococcus pneumoniae AP200 9726682 YP_003876262.1 CDS SPAP_0667 NC_014494.1 641157 641537 D Operon 297 Gene 2 COG0607 Rhodanese-related sulfurtransferase; rhodanese-related sulfurtransferase 641157..641537 Streptococcus pneumoniae AP200 9726683 YP_003876263.1 CDS SPAP_0668 NC_014494.1 641626 641853 D Operon 297 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 641626..641853 Streptococcus pneumoniae AP200 9726684 YP_003876264.1 CDS SPAP_0669 NC_014494.1 641893 642618 R Operon 298 Gene 1 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase complement(641893..642618) Streptococcus pneumoniae AP200 9726685 YP_003876265.1 CDS SPAP_0670 NC_014494.1 642780 644621 D Operon 299 Gene 1 COG1217 Predicted membrane GTPase involved in stress response; putative membrane GTPase involved in stress response 642780..644621 Streptococcus pneumoniae AP200 9726686 YP_003876266.1 CDS SPAP_0671 NC_014494.1 644641 644895 D Operon 299 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 644641..644895 Streptococcus pneumoniae AP200 9726687 YP_003876267.1 CDS SPAP_0672 NC_014494.1 645629 646669 D Operon 300 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 645629..646669 Streptococcus pneumoniae AP200 9726688 YP_003876268.1 CDS SPAP_0673 NC_014494.1 646844 647650 D Operon 301 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 646844..647650 Streptococcus pneumoniae AP200 9726689 YP_003876269.1 CDS SPAP_0674 NC_014494.1 647652 648293 D Operon 301 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 647652..648293 Streptococcus pneumoniae AP200 9726690 YP_003876270.1 CDS SPAP_0675 NC_014494.1 648397 649749 D Operon 302 Gene 1 COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoylalanine-D-glutamate ligase 648397..649749 Streptococcus pneumoniae AP200 9726691 YP_003876271.1 CDS SPAP_0676 NC_014494.1 649753 650811 D Operon 302 Gene 2 COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase 649753..650811 Streptococcus pneumoniae AP200 9726692 YP_003876272.1 CDS SPAP_0677 NC_014494.1 650821 652050 D Operon 302 Gene 3 COG1589 Cell division septal protein; cell division septal protein 650821..652050 Streptococcus pneumoniae AP200 9726693 YP_003876273.1 CDS SPAP_0678 NC_014494.1 652283 652984 D Operon 303 Gene 1 COG0284 Orotidine-5'-phosphate decarboxylase; orotidine-5'-phosphate decarboxylase 652283..652984 Streptococcus pneumoniae AP200 9726694 YP_003876274.1 CDS SPAP_0679 NC_014494.1 653018 653650 D Operon 303 Gene 2 COG0461 Orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 653018..653650 Streptococcus pneumoniae AP200 9726695 YP_003876275.1 CDS SPAP_0680 NC_014494.1 653883 654233 D Operon 304 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 653883..654233 Streptococcus pneumoniae AP200 9726696 YP_003876276.1 CDS SPAP_0681 NC_014494.1 654330 655094 D Operon 304 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 654330..655094 Streptococcus pneumoniae AP200 9726697 YP_003876277.1 CDS SPAP_0682 NC_014494.1 656207 656554 D Operon 305 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 656207..656554 Streptococcus pneumoniae AP200 9726698 YP_003876278.1 CDS SPAP_0683 NC_014494.1 656551 657198 D Operon 305 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 656551..657198 Streptococcus pneumoniae AP200 9726699 YP_003876279.1 CDS SPAP_0684 NC_014494.1 657285 658151 R Operon 306 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(657285..658151) Streptococcus pneumoniae AP200 9726700 YP_003876280.1 CDS SPAP_0685 NC_014494.1 658163 658669 R Operon 306 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein complement(658163..658669) Streptococcus pneumoniae AP200 9726701 YP_003876281.1 CDS SPAP_0686 NC_014494.1 658810 658920 R Operon 306 Gene 3 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase complement(658810..658920) Streptococcus pneumoniae AP200 9726702 YP_003876282.1 CDS SPAP_0687 NC_014494.1 658921 659598 R Operon 306 Gene 4 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(658921..659598) Streptococcus pneumoniae AP200 9726703 YP_003876283.1 CDS SPAP_0688 NC_014494.1 659558 660238 R Operon 306 Gene 5 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(659558..660238) Streptococcus pneumoniae AP200 9726704 YP_003876284.1 CDS SPAP_0689 NC_014494.1 660453 660599 D Operon 307 Gene 1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 660453..660599 Streptococcus pneumoniae AP200 9726705 YP_003876285.1 CDS SPAP_0690 NC_014494.1 660727 662217 D Operon 308 Gene 1 COG1190 Lysyl-tRNA synthetase (class II); Lysyl-tRNA synthetase (class II) 660727..662217 Streptococcus pneumoniae AP200 9726706 YP_003876286.1 CDS SPAP_0691 NC_014494.1 662841 663977 D Operon 309 Gene 1 COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; L-lactate dehydrogenase (FMN-dependent)-like alpha-hydroxy acid dehydrogenase 662841..663977 Streptococcus pneumoniae AP200 9726707 YP_003876287.1 CDS SPAP_0692 NC_014494.1 664532 665200 D Operon 310 Gene 1 COG0819 Putative transcription activator; putative transcriptional activator 664532..665200 Streptococcus pneumoniae AP200 9726708 YP_003876288.1 CDS SPAP_0693 NC_014494.1 665562 666308 D Operon 311 Gene 1 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 665562..666308 Streptococcus pneumoniae AP200 9726709 YP_003876289.1 CDS SPAP_0694 NC_014494.1 666310 666939 D Operon 311 Gene 2 COG0352 Thiamine monophosphate synthase; thiamine monophosphate synthase 666310..666939 Streptococcus pneumoniae AP200 9726710 YP_003876290.1 CDS SPAP_0695 NC_014494.1 667498 668058 D Operon 312 Gene 1 COG4721 Predicted membrane protein; hypothetical protein 667498..668058 Streptococcus pneumoniae AP200 9726711 YP_003876291.1 CDS SPAP_0696 NC_014494.1 668059 669444 D Operon 312 Gene 2 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 668059..669444 Streptococcus pneumoniae AP200 9726712 YP_003876292.1 CDS SPAP_0697 NC_014494.1 669446 670096 D Operon 312 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 669446..670096 Streptococcus pneumoniae AP200 9726713 YP_003876293.1 CDS SPAP_0698 NC_014494.1 670107 670799 D Operon 312 Gene 4 COG0819 Putative transcription activator; putative transcriptional activator 670107..670799 Streptococcus pneumoniae AP200 9726714 YP_003876294.1 CDS SPAP_0699 NC_014494.1 670804 671328 D Operon 312 Gene 5 COG4732 Predicted membrane protein; hypothetical protein 670804..671328 Streptococcus pneumoniae AP200 9726715 YP_003876295.1 CDS SPAP_0700 NC_014494.1 671328 672131 D Operon 312 Gene 6 COG2145 Hydroxyethylthiazole kinase, sugar kinase family; hydroxyethylthiazole kinase 671328..672131 Streptococcus pneumoniae AP200 9726716 YP_003876296.1 CDS SPAP_0701 NC_014494.1 672124 672756 D Operon 312 Gene 7 COG0352 Thiamine monophosphate synthase; thiamine monophosphate synthase 672124..672756 Streptococcus pneumoniae AP200 9726717 YP_003876297.1 CDS SPAP_0702 NC_014494.1 672966 673757 R Operon 313 Gene 1 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase complement(672966..673757) Streptococcus pneumoniae AP200 9726718 YP_003876298.1 CDS SPAP_0703 NC_014494.1 674123 674518 D Operon 314 Gene 1 COG3682 Predicted transcriptional regulator; putative transcriptional regulator 674123..674518 Streptococcus pneumoniae AP200 9726719 YP_003876299.1 CDS SPAP_0704 NC_014494.1 674529 674900 D Operon 314 Gene 2 COG4633 Uncharacterized protein conserved in bacteria; hypothetical protein 674529..674900 Streptococcus pneumoniae AP200 9726720 YP_003876300.1 CDS SPAP_0705 NC_014494.1 674910 677153 D Operon 314 Gene 3 COG2217 Cation transport ATPase; cation transport ATPase 674910..677153 Streptococcus pneumoniae AP200 9726721 YP_003876301.1 CDS SPAP_0706 NC_014494.1 677360 679135 D acetolactate synthase; pyruvate dehydrogenase (cytochrome); glyoxylate carboligase; phosphonopyruvate decarboxylase; Operon 315 Gene 1 COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; thiamine pyrophosphate-requiring enzyme 677360..679135 Streptococcus pneumoniae AP200 9726722 YP_003876302.1 CDS SPAP_0707 NC_014494.1 679246 679593 D Operon 316 Gene 1 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase 679246..679593 Streptococcus pneumoniae AP200 9726723 YP_003876303.1 CDS SPAP_0708 NC_014494.1 679805 680218 R Operon 317 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 complement(679805..680218) Streptococcus pneumoniae AP200 9726724 YP_003876304.1 CDS SPAP_0709 NC_014494.1 680250 680516 R transposase-like protein, ISSpn2 complement(680250..680516) Streptococcus pneumoniae AP200 9726725 YP_003876305.1 CDS SPAP_0710 NC_014494.1 680872 680967 R transposase-like protein, ISSpn2 complement(680872..680967) Streptococcus pneumoniae AP200 9726726 YP_003876306.1 CDS SPAP_0711 NC_014494.1 681032 681313 D Operon 319 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 681032..681313 Streptococcus pneumoniae AP200 9726727 YP_003876307.1 CDS SPAP_0712 NC_014494.1 681445 682389 D Operon 320 Gene 1 COG1482 Phosphomannose isomerase; phosphomannose isomerase 681445..682389 Streptococcus pneumoniae AP200 9726728 YP_003876308.1 CDS SPAP_0713 NC_014494.1 682410 683888 R Operon 321 Gene 1 COG0733 Na+-dependent transporters of the SNF family; Na+-dependent transporters of the SNF family complement(682410..683888) Streptococcus pneumoniae AP200 9726729 YP_003876309.1 CDS SPAP_0714 NC_014494.1 684054 684725 D Operon 322 Gene 1 COG0789 Predicted transcriptional regulators; putative transcriptional regulator 684054..684725 Streptococcus pneumoniae AP200 9726730 YP_003876310.1 CDS SPAP_0715 NC_014494.1 684745 685200 R Operon 323 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes complement(684745..685200) Streptococcus pneumoniae AP200 9726731 YP_003876311.1 CDS SPAP_0716 NC_014494.1 685220 686395 R Operon 323 Gene 2 COG2081 Predicted flavoproteins; putative flavoprotein complement(685220..686395) Streptococcus pneumoniae AP200 9726732 YP_003876312.1 CDS SPAP_0717 NC_014494.1 686454 687299 R Operon 323 Gene 3 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein complement(686454..687299) Streptococcus pneumoniae AP200 9726733 YP_003876313.1 CDS SPAP_0718 NC_014494.1 687424 687981 D Operon 324 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 687424..687981 Streptococcus pneumoniae AP200 9726734 YP_003876314.1 CDS SPAP_0719 NC_014494.1 688000 688467 D Operon 324 Gene 2 COG2131 Deoxycytidylate deaminase; deoxycytidylate deaminase 688000..688467 Streptococcus pneumoniae AP200 9726735 YP_003876315.1 CDS SPAP_0720 NC_014494.1 688556 689185 D Operon 324 Gene 3 COG0035 Uracil phosphoribosyltransferase; uracil phosphoribosyltransferase 688556..689185 Streptococcus pneumoniae AP200 9726736 YP_003876316.1 CDS SPAP_0721 NC_014494.1 689359 689949 D Operon 325 Gene 1 COG0740 Protease subunit of ATP-dependent Clp proteases; ATp-dependent Clp protease 689359..689949 Streptococcus pneumoniae AP200 9726737 YP_003876317.1 CDS SPAP_0722 NC_014494.1 690028 690276 D Operon 325 Gene 2 COG4471 Uncharacterized protein conserved in bacteria; hypothetical protein 690028..690276 Streptococcus pneumoniae AP200 9726738 YP_003876318.1 CDS SPAP_0723 NC_014494.1 690377 691537 D Operon 326 Gene 1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component; branched-chain amino acid ABC transporter periplasmic protein 690377..691537 Streptococcus pneumoniae AP200 9726739 YP_003876319.1 CDS SPAP_0724 NC_014494.1 691805 692674 D Operon 326 Gene 2 COG0559 Branched-chain amino acid ABC-type transport system, permease components; branched-chain amino acid ABC transporter permease 691805..692674 Streptococcus pneumoniae AP200 9726740 YP_003876320.1 CDS SPAP_0725 NC_014494.1 692678 693634 D Operon 326 Gene 3 COG4177 ABC-type branched-chain amino acid transport system, permease component; branched-chain amino acid ABC transporter permease 692678..693634 Streptococcus pneumoniae AP200 9726741 YP_003876321.1 CDS SPAP_0726 NC_014494.1 693634 694398 D Operon 326 Gene 4 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 693634..694398 Streptococcus pneumoniae AP200 9726742 YP_003876322.1 CDS SPAP_0727 NC_014494.1 694398 695108 D Operon 326 Gene 5 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component; branched-chain amino acid ABC transporter ATPase 694398..695108 Streptococcus pneumoniae AP200 9726743 YP_003876323.1 CDS SPAP_0728 NC_014494.1 695416 696072 D Operon 327 Gene 1 COG0517 FOG: CBS domain; hypothetical protein 695416..696072 Streptococcus pneumoniae AP200 9726744 YP_003876324.1 CDS SPAP_0729 NC_014494.1 696286 697275 D Operon 328 Gene 1 COG1186 Protein chain release factor B; protein chain release factor B 696286..697275 Streptococcus pneumoniae AP200 9726745 YP_003876325.1 CDS SPAP_0730 NC_014494.1 697293 697985 D Operon 328 Gene 2 COG2884 Predicted ATPase involved in cell division; putative ATPase 697293..697985 Streptococcus pneumoniae AP200 9726746 YP_003876326.1 CDS SPAP_0731 NC_014494.1 697978 698904 D Operon 328 Gene 3 COG2177 Cell division protein; cell division protein 697978..698904 Streptococcus pneumoniae AP200 9726747 YP_003876327.1 CDS SPAP_0732 NC_014494.1 698973 699068 D Operon 329 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 698973..699068 Streptococcus pneumoniae AP200 9726748 YP_003876328.1 CDS SPAP_0733 NC_014494.1 699190 701370 D Operon 330 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC 699190..701370 Streptococcus pneumoniae AP200 9726749 YP_003876329.1 CDS SPAP_0734 NC_014494.1 701422 702237 D Operon 330 Gene 2 COG3568 Metal-dependent hydrolase; metal-dependent hydrolase 701422..702237 Streptococcus pneumoniae AP200 9726750 YP_003876330.1 CDS SPAP_0735 NC_014494.1 702377 703720 D Operon 331 Gene 1 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase 702377..703720 Streptococcus pneumoniae AP200 9726751 YP_003876331.1 CDS SPAP_0736 NC_014494.1 703935 705125 D Operon 332 Gene 1 COG0192 S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 703935..705125 Streptococcus pneumoniae AP200 9726752 YP_003876332.1 CDS SPAP_0737 NC_014494.1 705678 706613 D Operon 333 Gene 1 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 705678..706613 Streptococcus pneumoniae AP200 9726753 YP_003876333.1 CDS SPAP_0738 NC_014494.1 706647 707684 D Operon 333 Gene 2 COG1466 DNA polymerase III, delta subunit; DNA polymerase III subunit delta 706647..707684 Streptococcus pneumoniae AP200 9726754 YP_003876334.1 CDS SPAP_0739 NC_014494.1 707857 708462 D Operon 334 Gene 1 protein supported gi|15900660|ref|NP_345264.1| superoxide dismutase, manganese-dependent; hypothetical protein 707857..708462 Streptococcus pneumoniae AP200 9726755 YP_003876335.1 CDS SPAP_0740 NC_014494.1 708619 709149 D Operon 335 Gene 1 COG4470 Uncharacterized protein conserved in bacteria; hypothetical protein 708619..709149 Streptococcus pneumoniae AP200 9726756 YP_003876336.1 CDS SPAP_0741 NC_014494.1 709170 710255 D Operon 335 Gene 2 COG0820 Predicted Fe-S-cluster redox enzyme; putative Fe-S-cluster redox enzyme 709170..710255 Streptococcus pneumoniae AP200 9726757 YP_003876337.1 CDS SPAP_0742 NC_014494.1 710255 710737 D Operon 335 Gene 3 COG4767 Glycopeptide antibiotics resistance protein; glycopeptide antibiotics resistance protein 710255..710737 Streptococcus pneumoniae AP200 9726758 YP_003876338.1 CDS SPAP_0743 NC_014494.1 710739 712280 D Operon 335 Gene 4 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 710739..712280 Streptococcus pneumoniae AP200 9726759 YP_003876339.1 CDS SPAP_0744 NC_014494.1 712446 713474 D transposase-like protein, IS1380 ISSpn5 712446..713474 Streptococcus pneumoniae AP200 9726760 YP_003876340.1 CDS SPAP_0745 NC_014494.1 713344 713790 D transposase-like protein, IS1380 ISSpn5 713344..713790 Streptococcus pneumoniae AP200 9726761 YP_003876341.1 CDS SPAP_0746 NC_014494.1 714042 714845 R Operon 337 Gene 1 COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family complement(714042..714845) Streptococcus pneumoniae AP200 9726762 YP_003876342.1 CDS SPAP_0747 NC_014494.1 714959 715150 R Operon 338 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(714959..715150) Streptococcus pneumoniae AP200 9726763 YP_003876343.1 CDS SPAP_0748 NC_014494.1 715629 715838 R Operon 339 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(715629..715838) Streptococcus pneumoniae AP200 9726764 YP_003876344.1 CDS SPAP_0749 NC_014494.1 716008 716280 D Operon 340 Gene 1 protein supported gi|148997148|ref|ZP_01824802.1| ribosomal protein S16; hypothetical protein 716008..716280 Streptococcus pneumoniae AP200 9726765 YP_003876345.1 CDS SPAP_0750 NC_014494.1 716300 716539 D Operon 340 Gene 2 COG1837 Predicted RNA-binding protein (contains KH domain); putative RNA-binding protein 716300..716539 Streptococcus pneumoniae AP200 9726766 YP_003876346.1 CDS SPAP_0751 NC_014494.1 717116 717904 D Operon 341 Gene 1 protein supported gi|149007659|ref|ZP_01831276.1| 30S ribosomal protein S16; hypothetical protein 717116..717904 Streptococcus pneumoniae AP200 9726767 YP_003876347.1 CDS SPAP_0752 NC_014494.1 717935 718060 D Operon 341 Gene 2 COG0806 RimM protein, required for 16S rRNA processing; RimM protein, required for 16S rRNA processing 717935..718060 Streptococcus pneumoniae AP200 9726768 YP_003876348.1 CDS SPAP_0753 NC_014494.1 718053 718454 D Operon 341 Gene 3 COG0806 RimM protein, required for 16S rRNA processing; RimM protein, required for 16S rRNA processing 718053..718454 Streptococcus pneumoniae AP200 9726769 YP_003876349.1 CDS SPAP_0754 NC_014494.1 718444 719163 D Operon 341 Gene 4 COG0336 tRNA-(guanine-N1)-methyltransferase; tRNA-(guanine-N1)-methyltransferase 718444..719163 Streptococcus pneumoniae AP200 9726770 YP_003876350.1 CDS SPAP_0755 NC_014494.1 719175 719513 D Operon 341 Gene 5 COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; oxygen-sensitive ribonucleoside-triphosphate reductase 719175..719513 Streptococcus pneumoniae AP200 9726771 YP_003876351.1 CDS SPAP_0756 NC_014494.1 719543 719863 R Operon 342 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(719543..719863) Streptococcus pneumoniae AP200 9726772 YP_003876352.1 CDS SPAP_0757 NC_014494.1 719961 720176 D Operon 343 Gene 1 COG4443 Uncharacterized protein conserved in bacteria; hypothetical protein 719961..720176 Streptococcus pneumoniae AP200 9726773 YP_003876353.1 CDS SPAP_0758 NC_014494.1 720380 720916 R Operon 344 Gene 1 COG1268 Uncharacterized conserved protein; hypothetical protein complement(720380..720916) Streptococcus pneumoniae AP200 9726774 YP_003876354.1 CDS SPAP_0759 NC_014494.1 721112 722458 R Operon 345 Gene 1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein complement(721112..722458) Streptococcus pneumoniae AP200 9726775 YP_003876355.1 CDS SPAP_0760 NC_014494.1 722744 723943 D Operon 346 Gene 1 COG0845 Membrane-fusion protein; membrane-fusion protein 722744..723943 Streptococcus pneumoniae AP200 9726776 YP_003876356.1 CDS SPAP_0761 NC_014494.1 723927 724628 D Operon 346 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 723927..724628 Streptococcus pneumoniae AP200 9726777 YP_003876357.1 CDS SPAP_0762 NC_014494.1 724630 725889 D Operon 346 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 724630..725889 Streptococcus pneumoniae AP200 9726778 YP_003876358.1 CDS SPAP_0763 NC_014494.1 726013 728010 D Operon 347 Gene 1 COG0143 Methionyl-tRNA synthetase; methionyl-tRNA synthetase 726013..728010 Streptococcus pneumoniae AP200 9726779 YP_003876359.1 CDS SPAP_0764 NC_014494.1 728060 728341 D Operon 347 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 728060..728341 Streptococcus pneumoniae AP200 9726780 YP_003876360.1 CDS SPAP_0765 NC_014494.1 728431 728751 D Operon 347 Gene 3 COG1695 Predicted transcriptional regulators; putative transcriptional regulator 728431..728751 Streptococcus pneumoniae AP200 9726781 YP_003876361.1 CDS SPAP_0766 NC_014494.1 728755 729570 D Operon 347 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 728755..729570 Streptococcus pneumoniae AP200 9726782 YP_003876362.1 CDS SPAP_0767 NC_014494.1 729645 730571 D Operon 347 Gene 5 COG4989 Predicted oxidoreductase; putative oxidoreductase 729645..730571 Streptococcus pneumoniae AP200 9726783 YP_003876363.1 CDS SPAP_0768 NC_014494.1 730671 730907 D Operon 348 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 730671..730907 Streptococcus pneumoniae AP200 9726784 YP_003876364.1 CDS SPAP_0769 NC_014494.1 730900 731598 D Operon 348 Gene 2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); fehydrogenase 730900..731598 Streptococcus pneumoniae AP200 9726785 YP_003876365.1 CDS SPAP_0770 NC_014494.1 731609 732109 D Operon 348 Gene 3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 731609..732109 Streptococcus pneumoniae AP200 9726786 YP_003876366.1 CDS SPAP_0771 NC_014494.1 732087 732956 D Operon 348 Gene 4 COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; phosphoenolpyruvate synthase 732087..732956 Streptococcus pneumoniae AP200 9726787 YP_003876367.1 CDS SPAP_0772 NC_014494.1 732931 733371 D Operon 348 Gene 5 COG4405 Uncharacterized protein conserved in bacteria; hypothetical protein 732931..733371 Streptococcus pneumoniae AP200 9726788 YP_003876368.1 CDS SPAP_0773 NC_014494.1 733494 736040 D Operon 349 Gene 1 COG0308 Aminopeptidase N; aminopeptidase N 733494..736040 Streptococcus pneumoniae AP200 9726789 YP_003876369.1 CDS SPAP_0774 NC_014494.1 736148 736822 D Operon 350 Gene 1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 736148..736822 Streptococcus pneumoniae AP200 9726790 YP_003876370.1 CDS SPAP_0775 NC_014494.1 736812 738146 D Operon 350 Gene 2 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 736812..738146 Streptococcus pneumoniae AP200 9726791 YP_003876371.1 CDS SPAP_0776 NC_014494.1 738180 738467 R Operon 351 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(738180..738467) Streptococcus pneumoniae AP200 9726792 YP_003876372.1 CDS SPAP_0777 NC_014494.1 738607 739536 D Operon 352 Gene 1 COG0826 Collagenase and related proteases; collagenase-like protease 738607..739536 Streptococcus pneumoniae AP200 9726793 YP_003876373.1 CDS SPAP_0778 NC_014494.1 739736 742186 D Operon 353 Gene 1 COG1199 Rad3-related DNA helicases; Rad3-related DNA helicase 739736..742186 Streptococcus pneumoniae AP200 9726794 YP_003876374.1 CDS SPAP_0779 NC_014494.1 742223 743446 D Operon 353 Gene 2 COG0772 Bacterial cell division membrane protein; cell division membrane protein 742223..743446 Streptococcus pneumoniae AP200 9726795 YP_003876375.1 CDS SPAP_0780 NC_014494.1 743457 744011 D Operon 353 Gene 3 COG0693 Putative intracellular protease/amidase; putative intracellular protease/amidase 743457..744011 Streptococcus pneumoniae AP200 9726796 YP_003876376.1 CDS SPAP_0781 NC_014494.1 744087 744659 D Operon 353 Gene 4 COG0546 Predicted phosphatases; putative phosphatase 744087..744659 Streptococcus pneumoniae AP200 9726797 YP_003876377.1 CDS SPAP_0782 NC_014494.1 744674 746620 D Operon 353 Gene 5 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; type IIA topoisomerase subunit B 744674..746620 Streptococcus pneumoniae AP200 9726798 YP_003876378.1 CDS SPAP_0783 NC_014494.1 746702 748429 D Operon 353 Gene 6 COG4477 Negative regulator of septation ring formation; Negative regulator of septation ring formation 746702..748429 Streptococcus pneumoniae AP200 9726799 YP_003876379.1 CDS SPAP_0784 NC_014494.1 749159 749482 R transposase-like protein, ISSpn_AP200_7 complement(749159..749482) Streptococcus pneumoniae AP200 9726800 YP_003876380.1 CDS SPAP_0785 NC_014494.1 749743 750042 R Operon 355 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(749743..750042) Streptococcus pneumoniae AP200 9726801 YP_003876381.1 CDS SPAP_0786 NC_014494.1 750207 750470 R Operon 356 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes complement(750207..750470) Streptococcus pneumoniae AP200 9726802 YP_003876382.1 CDS SPAP_0787 NC_014494.1 750722 751090 D transposase-like protein, IS630 750722..751090 Streptococcus pneumoniae AP200 9726803 YP_003876383.1 CDS SPAP_0788 NC_014494.1 751109 751369 R Operon 358 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(751109..751369) Streptococcus pneumoniae AP200 9726804 YP_003876384.1 CDS SPAP_0789 NC_014494.1 751510 751692 D Operon 359 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 751510..751692 Streptococcus pneumoniae AP200 9726805 YP_003876385.1 CDS SPAP_0790 NC_014494.1 751899 754157 R Operon 360 Gene 1 protein supported gi|163764771|ref|ZP_02171825.1| ribosomal protein S8; hypothetical protein complement(751899..754157) Streptococcus pneumoniae AP200 9726806 YP_003876386.1 CDS SPAP_0791 NC_014494.1 754386 754616 R Operon 361 Gene 1 COG4703 Uncharacterized protein conserved in bacteria; hypothetical protein complement(754386..754616) Streptococcus pneumoniae AP200 9726807 YP_003876387.1 CDS SPAP_0792 NC_014494.1 754806 755489 D Operon 362 Gene 1 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease 754806..755489 Streptococcus pneumoniae AP200 9726808 YP_003876388.1 CDS SPAP_0793 NC_014494.1 755489 756223 D Operon 362 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 755489..756223 Streptococcus pneumoniae AP200 9726809 YP_003876389.1 CDS SPAP_0794 NC_014494.1 756377 757234 D Operon 363 Gene 1 COG0190 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase 756377..757234 Streptococcus pneumoniae AP200 9726810 YP_003876390.1 CDS SPAP_0795 NC_014494.1 757376 758248 D Operon 364 Gene 1 COG0063 Predicted sugar kinase; putative sugar kinase 757376..758248 Streptococcus pneumoniae AP200 9726811 YP_003876391.1 CDS SPAP_0796 NC_014494.1 758530 759213 D Operon 365 Gene 1 COG0120 Ribose 5-phosphate isomerase; ribose 5-phosphate isomerase 758530..759213 Streptococcus pneumoniae AP200 9726812 YP_003876392.1 CDS SPAP_0797 NC_014494.1 759227 760438 D Operon 365 Gene 2 COG1015 Phosphopentomutase; phosphopentomutase 759227..760438 Streptococcus pneumoniae AP200 9726813 YP_003876393.1 CDS SPAP_0798 NC_014494.1 760440 760982 D Operon 365 Gene 3 COG3797 Uncharacterized protein conserved in bacteria; hypothetical protein 760440..760982 Streptococcus pneumoniae AP200 9726814 YP_003876394.1 CDS SPAP_0799 NC_014494.1 760998 761807 D Operon 365 Gene 4 COG0005 Purine nucleoside phosphorylase; purine nucleoside phosphorylase 760998..761807 Streptococcus pneumoniae AP200 9726815 YP_003876395.1 CDS SPAP_0800 NC_014494.1 762283 762678 D Operon 366 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 762283..762678 Streptococcus pneumoniae AP200 9726816 YP_003876396.1 CDS SPAP_0801 NC_014494.1 762733 763263 D Operon 366 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 762733..763263 Streptococcus pneumoniae AP200 9726817 YP_003876397.1 CDS SPAP_0802 NC_014494.1 763288 763800 D Operon 366 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 763288..763800 Streptococcus pneumoniae AP200 9726818 YP_003876398.1 CDS SPAP_0803 NC_014494.1 764454 765164 D Operon 367 Gene 1 COG0813 Purine-nucleoside phosphorylase; purine-nucleoside phosphorylase 764454..765164 Streptococcus pneumoniae AP200 9726819 YP_003876399.1 CDS SPAP_0804 NC_014494.1 765187 765711 R Operon 368 Gene 1 COG0563 Adenylate kinase and related kinases; adenylate kinase-like kinase complement(765187..765711) Streptococcus pneumoniae AP200 9726820 YP_003876400.1 CDS SPAP_0805 NC_014494.1 765764 766015 R Operon 369 Gene 1 protein supported gi|242245117|ref|ZP_04799554.1| 30S ribosomal protein S20; hypothetical protein complement(765764..766015) Streptococcus pneumoniae AP200 9726821 YP_003876401.1 CDS SPAP_0806 NC_014494.1 766068 766988 R Operon 369 Gene 2 COG1072 Panthothenate kinase; panthothenate kinase complement(766068..766988) Streptococcus pneumoniae AP200 9726822 YP_003876402.1 CDS SPAP_0807 NC_014494.1 767178 767414 D Operon 370 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 767178..767414 Streptococcus pneumoniae AP200 9726823 YP_003876403.1 CDS SPAP_0808 NC_014494.1 767788 768378 D Operon 371 Gene 1 COG2813 16S RNA G1207 methylase RsmC; 16S RNA G1207 methylase RsmC 767788..768378 Streptococcus pneumoniae AP200 9726824 YP_003876404.1 CDS SPAP_0809 NC_014494.1 768375 769652 D Operon 371 Gene 2 COG0213 Thymidine phosphorylase; thymidine phosphorylase 768375..769652 Streptococcus pneumoniae AP200 9726825 YP_003876405.1 CDS SPAP_0810 NC_014494.1 769670 770332 D Operon 371 Gene 3 COG0274 Deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 769670..770332 Streptococcus pneumoniae AP200 9726826 YP_003876406.1 CDS SPAP_0811 NC_014494.1 770319 770708 D Operon 371 Gene 4 COG0295 Cytidine deaminase; cytidine deaminase 770319..770708 Streptococcus pneumoniae AP200 9726827 YP_003876407.1 CDS SPAP_0812 NC_014494.1 770799 771851 D Operon 371 Gene 5 COG1744 Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein; ABC transporter periplasmic protein/surface lipoprotein 770799..771851 Streptococcus pneumoniae AP200 9726828 YP_003876408.1 CDS SPAP_0813 NC_014494.1 771995 773530 D Operon 371 Gene 6 COG3845 ABC-type uncharacterized transport systems, ATPase components; ABC transporter ATPase 771995..773530 Streptococcus pneumoniae AP200 9726829 YP_003876409.1 CDS SPAP_0814 NC_014494.1 773523 774581 D Operon 371 Gene 7 COG4603 ABC-type uncharacterized transport system, permease component; ABC transporter permease 773523..774581 Streptococcus pneumoniae AP200 9726830 YP_003876410.1 CDS SPAP_0815 NC_014494.1 774584 775540 D Operon 371 Gene 8 COG1079 Uncharacterized ABC-type transport system, permease component; ABC transporter permease 774584..775540 Streptococcus pneumoniae AP200 9726831 YP_003876411.1 CDS SPAP_0816 NC_014494.1 775625 775837 D Operon 371 Gene 9 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 775625..775837 Streptococcus pneumoniae AP200 9726832 YP_003876412.1 CDS SPAP_0817 NC_014494.1 775974 776141 D Operon 372 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 775974..776141 Streptococcus pneumoniae AP200 9726833 YP_003876413.1 CDS SPAP_0818 NC_014494.1 776141 776974 D Operon 372 Gene 2 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 776141..776974 Streptococcus pneumoniae AP200 9726834 YP_003876414.1 CDS SPAP_0819 NC_014494.1 777017 777658 R Operon 373 Gene 1 COG0344 Predicted membrane protein; hypothetical protein complement(777017..777658) Streptococcus pneumoniae AP200 9726835 YP_003876415.1 CDS SPAP_0820 NC_014494.1 777794 779737 D Operon 374 Gene 1 COG0187 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit; type IIA topoisomerase subunit B 777794..779737 Streptococcus pneumoniae AP200 9726836 YP_003876416.1 CDS SPAP_0821 NC_014494.1 779752 779844 D Operon 374 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 779752..779844 Streptococcus pneumoniae AP200 9726837 YP_003876417.1 CDS SPAP_0822 NC_014494.1 779858 779983 D Operon 374 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 779858..779983 Streptococcus pneumoniae AP200 9726838 YP_003876418.1 CDS SPAP_0823 NC_014494.1 780193 782628 D Operon 375 Gene 1 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; type IIA topoisomerase subunit A 780193..782628 Streptococcus pneumoniae AP200 9726839 YP_003876419.1 CDS SPAP_0824 NC_014494.1 782760 783782 D Operon 376 Gene 1 COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase 782760..783782 Streptococcus pneumoniae AP200 9726840 YP_003876420.1 CDS SPAP_0825 NC_014494.1 783838 784542 D Operon 376 Gene 2 protein supported gi|148997067|ref|ZP_01824721.1| 30S ribosomal protein S1; hypothetical protein 783838..784542 Streptococcus pneumoniae AP200 9726841 YP_003876421.1 CDS SPAP_0826 NC_014494.1 784607 785296 D Operon 376 Gene 3 COG3819 Predicted membrane protein; hypothetical protein 784607..785296 Streptococcus pneumoniae AP200 9726842 YP_003876422.1 CDS SPAP_0827 NC_014494.1 785293 786216 D Operon 376 Gene 4 COG3817 Predicted membrane protein; hypothetical protein 785293..786216 Streptococcus pneumoniae AP200 9726843 YP_003876423.1 CDS SPAP_0828 NC_014494.1 786231 786875 D Operon 376 Gene 5 COG2039; N-terminal pyroglutamyl peptidase; pyrrolidone-carboxylate peptidase 786231..786875 Streptococcus pneumoniae AP200 9726844 YP_003876424.1 CDS SPAP_0829 NC_014494.1 787043 787273 D Operon 376 Gene 6 Putative gene predicted by FgenesB; hypothetical protein 787043..787273 Streptococcus pneumoniae AP200 9726845 YP_003876425.1 CDS SPAP_0832 NC_014494.1 787646 788848 D Operon 377 Gene 1 protein supported gi|15902808|ref|NP_358358.1| 30S ribosomal protein S1; hypothetical protein 787646..788848 Streptococcus pneumoniae AP200 9726848 YP_003876426.1 CDS SPAP_0833 NC_014494.1 788933 789472 R Operon 378 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(788933..789472) Streptococcus pneumoniae AP200 9726849 YP_003876427.1 CDS SPAP_0834 NC_014494.1 789732 790250 R Operon 379 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 complement(789732..790250) Streptococcus pneumoniae AP200 9726850 YP_003876428.1 CDS SPAP_0835 NC_014494.1 790444 790941 D Operon 380 Gene 1 protein supported gi|15900747|ref|NP_345351.1| hypothetical protein SP_0864; hypothetical protein 790444..790941 Streptococcus pneumoniae AP200 9726851 YP_003876429.1 CDS SPAP_0836 NC_014494.1 790941 792596 D Operon 380 Gene 2 COG2812 DNA polymerase III, gamma/tau subunits; DNA polymerase III subunits gamma/tau 790941..792596 Streptococcus pneumoniae AP200 9726852 YP_003876430.1 CDS SPAP_0837 NC_014494.1 792624 792818 D Operon 380 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 792624..792818 Streptococcus pneumoniae AP200 9726853 YP_003876431.1 CDS SPAP_0838 NC_014494.1 792968 793738 D Operon 381 Gene 1 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Fe-S cluster assemble ABC transporter ATPase 792968..793738 Streptococcus pneumoniae AP200 9726854 YP_003876432.1 CDS SPAP_0839 NC_014494.1 793766 795028 D Operon 381 Gene 2 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Fe-S cluster assemble ABC transporter permease 793766..795028 Streptococcus pneumoniae AP200 9726855 YP_003876433.1 CDS SPAP_0840 NC_014494.1 795039 796265 D Operon 381 Gene 3 COG0520 Selenocysteine lyase; selenocysteine lyase 795039..796265 Streptococcus pneumoniae AP200 9726856 YP_003876434.1 CDS SPAP_0841 NC_014494.1 796252 796692 D Operon 381 Gene 4 COG0822 NifU homolog involved in Fe-S cluster formation; NifU-like protein 796252..796692 Streptococcus pneumoniae AP200 9726857 YP_003876435.1 CDS SPAP_0842 NC_014494.1 796746 798158 D Operon 381 Gene 5 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component; Fe-S cluster assemble ABC transporter permease 796746..798158 Streptococcus pneumoniae AP200 9726858 YP_003876436.1 CDS SPAP_0843 NC_014494.1 798389 799630 R Operon 382 Gene 1 COG1686 D-alanyl-D-alanine carboxypeptidase; D-alanyl-D-alanine carboxypeptidase complement(798389..799630) Streptococcus pneumoniae AP200 9726859 YP_003876437.1 CDS SPAP_0844 NC_014494.1 799733 800842 D Operon 383 Gene 1 COG0628 Predicted permease; putative permease 799733..800842 Streptococcus pneumoniae AP200 9726860 YP_003876438.1 CDS SPAP_0845 NC_014494.1 801772 801987 D Operon 384 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 801772..801987 Streptococcus pneumoniae AP200 9726861 YP_003876439.1 CDS SPAP_0848 NC_014494.1 802254 802994 D Operon 384 Gene 3 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 802254..802994 Streptococcus pneumoniae AP200 9726863 YP_003876440.1 CDS SPAP_0849 NC_014494.1 802991 803902 D Operon 384 Gene 4 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB 802991..803902 Streptococcus pneumoniae AP200 9726864 YP_003876441.1 CDS SPAP_0850 NC_014494.1 803899 805851 D Operon 384 Gene 5 COG1299 Phosphotransferase system, fructose-specific IIC component; PTS system fructose-specific transporter subunit IIC 803899..805851 Streptococcus pneumoniae AP200 9726865 YP_003876442.1 CDS SPAP_0851 NC_014494.1 805937 808240 D Operon 384 Gene 6 COG1674 DNA segregation ATPase FtsK/SpoIIIE and related proteins; DNA segregation ATPase FtsK/SpoIIIE-like protein 805937..808240 Streptococcus pneumoniae AP200 9726866 YP_003876443.1 CDS SPAP_0852 NC_014494.1 808284 808718 R Operon 385 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(808284..808718) Streptococcus pneumoniae AP200 9726867 YP_003876444.1 CDS SPAP_0853 NC_014494.1 808881 809621 D Operon 386 Gene 1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; transposase-like protein, IS1515 808881..809621 Streptococcus pneumoniae AP200 9726868 YP_003876445.1 CDS SPAP_0854 NC_014494.1 809633 810010 D Operon 386 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 809633..810010 Streptococcus pneumoniae AP200 9726869 YP_003876446.1 CDS SPAP_0855 NC_014494.1 810036 811838 D Operon 386 Gene 3 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 810036..811838 Streptococcus pneumoniae AP200 9726870 YP_003876447.1 CDS SPAP_0856 NC_014494.1 811848 812225 D Operon 386 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 811848..812225 Streptococcus pneumoniae AP200 9726871 YP_003876448.1 CDS SPAP_0857 NC_014494.1 812385 813527 D Operon 387 Gene 1 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine sulfinate desulfinase/cysteine desulfurase-like protein 812385..813527 Streptococcus pneumoniae AP200 9726872 YP_003876449.1 CDS SPAP_0858 NC_014494.1 813536 814750 D Operon 387 Gene 2 COG0301 Thiamine biosynthesis ATP pyrophosphatase; thiamine biosynthesis ATP pyrophosphatase 813536..814750 Streptococcus pneumoniae AP200 9726873 YP_003876450.1 CDS SPAP_0859 NC_014494.1 814885 815457 D Operon 388 Gene 1 COG2819 Predicted hydrolase of the alpha/beta superfamily; putative alpha/beta superfamily hydrolase 814885..815457 Streptococcus pneumoniae AP200 9726874 YP_003876451.1 CDS SPAP_0860 NC_014494.1 815720 816055 D Operon 389 Gene 1 COG4947 Uncharacterized protein conserved in bacteria; hypothetical protein 815720..816055 Streptococcus pneumoniae AP200 9726875 YP_003876452.1 CDS SPAP_0861 NC_014494.1 816052 816459 D Operon 389 Gene 2 COG4947 Uncharacterized protein conserved in bacteria; hypothetical protein 816052..816459 Streptococcus pneumoniae AP200 9726876 YP_003876453.1 CDS SPAP_0862 NC_014494.1 816472 817638 D Operon 389 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 816472..817638 Streptococcus pneumoniae AP200 9726877 YP_003876454.1 CDS SPAP_0863 NC_014494.1 818146 818859 D Operon 390 Gene 1 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit 818146..818859 Streptococcus pneumoniae AP200 9726878 YP_003876455.1 CDS SPAP_0864 NC_014494.1 818937 819182 D Operon 390 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 818937..819182 Streptococcus pneumoniae AP200 9726879 YP_003876456.1 CDS SPAP_0865 NC_014494.1 819264 820037 D Operon 391 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 819264..820037 Streptococcus pneumoniae AP200 9726880 YP_003876457.1 CDS SPAP_0866 NC_014494.1 820034 820861 D Operon 391 Gene 2 COG1484 DNA replication protein; DNA replication protein 820034..820861 Streptococcus pneumoniae AP200 9726881 YP_003876458.1 CDS SPAP_0867 NC_014494.1 820854 821339 D Operon 391 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 820854..821339 Streptococcus pneumoniae AP200 9726882 YP_003876459.1 CDS SPAP_0868 NC_014494.1 821336 822070 D Operon 391 Gene 4 COG3645 Uncharacterized phage-encoded protein; hypothetical protein 821336..822070 Streptococcus pneumoniae AP200 9726883 YP_003876460.1 CDS SPAP_0869 NC_014494.1 822048 823859 D similar to MGAS10750_Spy1683; TraG/TraD family member; type IV secretory pathway protein VirD4 822048..823859 Streptococcus pneumoniae AP200 9726884 YP_003876461.1 CDS SPAP_0870 NC_014494.1 823942 824412 D Operon 391 Gene 6 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 823942..824412 Streptococcus pneumoniae AP200 9726885 YP_003876462.1 CDS SPAP_0871 NC_014494.1 824681 824875 D Operon 392 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 824681..824875 Streptococcus pneumoniae AP200 9726886 YP_003876463.1 CDS SPAP_0872 NC_014494.1 824939 825457 D Operon 392 Gene 2 COG4283 Uncharacterized conserved protein; hypothetical protein 824939..825457 Streptococcus pneumoniae AP200 9726887 YP_003876464.1 CDS SPAP_0873 NC_014494.1 825495 825917 D Operon 392 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 825495..825917 Streptococcus pneumoniae AP200 9726888 YP_003876465.1 CDS SPAP_0874 NC_014494.1 825985 826602 D Operon 392 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 825985..826602 Streptococcus pneumoniae AP200 9726889 YP_003876466.1 CDS SPAP_0875 NC_014494.1 826824 827135 D Operon 393 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 826824..827135 Streptococcus pneumoniae AP200 9726890 YP_003876467.1 CDS SPAP_0876 NC_014494.1 827137 827352 D Operon 393 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 827137..827352 Streptococcus pneumoniae AP200 9726891 YP_003876468.1 CDS SPAP_0877 NC_014494.1 827363 828226 D Operon 393 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 827363..828226 Streptococcus pneumoniae AP200 9726892 YP_003876469.1 CDS SPAP_0878 NC_014494.1 828236 828526 D Operon 393 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 828236..828526 Streptococcus pneumoniae AP200 9726893 YP_003876470.1 CDS SPAP_0879 NC_014494.1 828528 828938 D Operon 393 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 828528..828938 Streptococcus pneumoniae AP200 9726894 YP_003876471.1 CDS SPAP_0880 NC_014494.1 828829 831252 D Operon 393 Gene 6 COG3451 Type IV secretory pathway, VirB4 components; type IV secretory pathway, VirB4 component 828829..831252 Streptococcus pneumoniae AP200 9726895 YP_003876472.1 CDS SPAP_0881 NC_014494.1 831260 833839 D Operon 393 Gene 7 COG0791 Cell wall-associated hydrolases (invasion-associated proteins); cell wall-associated hydrolase 831260..833839 Streptococcus pneumoniae AP200 9726896 YP_003876473.1 CDS SPAP_0882 NC_014494.1 833854 834093 D Operon 393 Gene 8 Putative gene predicted by FgenesB; hypothetical protein 833854..834093 Streptococcus pneumoniae AP200 9726897 YP_003876474.1 CDS SPAP_0883 NC_014494.1 834080 835663 D Operon 393 Gene 9 Putative gene predicted by FgenesB; hypothetical protein 834080..835663 Streptococcus pneumoniae AP200 9726898 YP_003876475.1 CDS SPAP_0884 NC_014494.1 835678 836544 D Operon 393 Gene 10 Putative gene predicted by FgenesB; hypothetical protein 835678..836544 Streptococcus pneumoniae AP200 9726899 YP_003876476.1 CDS SPAP_0885 NC_014494.1 836656 837231 D Operon 394 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 836656..837231 Streptococcus pneumoniae AP200 9726900 YP_003876477.1 CDS SPAP_0886 NC_014494.1 837224 838207 D Operon 394 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 837224..838207 Streptococcus pneumoniae AP200 9726901 YP_003876478.1 CDS SPAP_0887 NC_014494.1 838300 840021 D Operon 395 Gene 1 COG0550 Topoisomerase IA; topoisomerase IA 838300..840021 Streptococcus pneumoniae AP200 9726902 YP_003876479.1 CDS SPAP_0888 NC_014494.1 840014 840979 D Operon 395 Gene 2 COG0270 Site-specific DNA methylase; site-specific DNA methylase 840014..840979 Streptococcus pneumoniae AP200 9726903 YP_003876480.1 CDS SPAP_0889 NC_014494.1 840966 847262 D Operon 395 Gene 3 COG4646 DNA methylase; DNA methylase 840966..847262 Streptococcus pneumoniae AP200 9726904 YP_003876481.1 CDS SPAP_0890 NC_014494.1 847818 849353 D Operon 396 Gene 1 COG3344 Retron-type reverse transcriptase; retron-type reverse transcriptase 847818..849353 Streptococcus pneumoniae AP200 9726905 YP_003876482.1 CDS SPAP_0891 NC_014494.1 850994 851650 D Operon 397 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 850994..851650 Streptococcus pneumoniae AP200 9726906 YP_003876483.1 CDS SPAP_0892 NC_014494.1 852209 852835 D Operon 398 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 852209..852835 Streptococcus pneumoniae AP200 9726907 YP_003876484.1 CDS SPAP_0893 NC_014494.1 852920 853801 D Operon 398 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 852920..853801 Streptococcus pneumoniae AP200 9726908 YP_003876485.1 CDS SPAP_0894 NC_014494.1 853734 855440 D similar to MGAS10750_Spy170; tetronasin resistance transmembrane protein 853734..855440 Streptococcus pneumoniae AP200 9726909 YP_003876486.1 CDS SPAP_0895 NC_014494.1 856021 856227 R Operon 399 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(856021..856227) Streptococcus pneumoniae AP200 9726910 YP_003876487.1 CDS erm(TR) NC_014494.1 856174 856905 D Operon 400 Gene 1 COG0030 Dimethyladenosine transferase (rRNA methylation); dimethyladenosine transferase 856174..856905 Streptococcus pneumoniae AP200 9726911 YP_003876488.1 CDS SPAP_0897 NC_014494.1 857122 857646 D Operon 401 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 857122..857646 Streptococcus pneumoniae AP200 9726912 YP_003876489.1 CDS SPAP_0898 NC_014494.1 858667 859092 D Operon 402 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 858667..859092 Streptococcus pneumoniae AP200 9726913 YP_003876490.1 CDS SPAP_0899 NC_014494.1 859297 859650 D Operon 403 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 859297..859650 Streptococcus pneumoniae AP200 9726914 YP_003876491.1 CDS SPAP_0900 NC_014494.1 860132 861472 R Operon 404 Gene 1 COG3843 Type IV secretory pathway, VirD2 components (relaxase); type IV secretory pathway, VirD2 components (relaxase) complement(860132..861472) Streptococcus pneumoniae AP200 9726915 YP_003876492.1 CDS SPAP_0901 NC_014494.1 861465 861821 R Operon 404 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(861465..861821) Streptococcus pneumoniae AP200 9726916 YP_003876493.1 CDS SPAP_0902 NC_014494.1 862000 862335 R Operon 405 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(862000..862335) Streptococcus pneumoniae AP200 9726917 YP_003876494.1 CDS SPAP_0903 NC_014494.1 862328 862561 R Operon 405 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(862328..862561) Streptococcus pneumoniae AP200 9726918 YP_003876495.1 CDS SPAP_0904 NC_014494.1 862668 863150 R Operon 406 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(862668..863150) Streptococcus pneumoniae AP200 9726919 YP_003876496.1 CDS SPAP_0905 NC_014494.1 863159 863707 R Operon 406 Gene 2 COG2856 Predicted Zn peptidase; putative Zn peptidase complement(863159..863707) Streptococcus pneumoniae AP200 9726920 YP_003876497.1 CDS SPAP_0906 NC_014494.1 863716 864117 R Operon 406 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(863716..864117) Streptococcus pneumoniae AP200 9726921 YP_003876498.1 CDS SPAP_0907 NC_014494.1 864267 864827 D similar to MGAS10750_Spy1715; hypothetical protein 864267..864827 Streptococcus pneumoniae AP200 9726922 YP_003876499.1 CDS SPAP_0908 NC_014494.1 865097 865507 D Operon 407 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 865097..865507 Streptococcus pneumoniae AP200 9726923 YP_003876500.1 CDS SPAP_0909 NC_014494.1 865984 866205 D similar to HP Uuresero_01771 Ureaplasma urealyticum serovar 9; hypothetical protein 865984..866205 Streptococcus pneumoniae AP200 9726924 YP_003876501.1 CDS SPAP_0910 NC_014494.1 866306 867976 D Operon 409 Gene 1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase 866306..867976 Streptococcus pneumoniae AP200 9726925 YP_003876502.1 CDS SPAP_0911 NC_014494.1 867976 869646 D similar to MGAS10750_Spy1718; site-specific recombinase 867976..869646 Streptococcus pneumoniae AP200 9726926 YP_003876503.1 CDS SPAP_0912 NC_014494.1 869639 871132 D Operon 410 Gene 2 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase 869639..871132 Streptococcus pneumoniae AP200 9726927 YP_003876504.1 CDS SPAP_0913 NC_014494.1 871308 872099 D Operon 411 Gene 1 COG0286 Type I restriction-modification system methyltransferase subunit; type I restriction-modification system methyltransferase subunit 871308..872099 Streptococcus pneumoniae AP200 9726928 YP_003876505.1 CDS SPAP_0914 NC_014494.1 872112 872654 D Operon 411 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 872112..872654 Streptococcus pneumoniae AP200 9726929 YP_003876506.1 CDS SPAP_0915 NC_014494.1 872651 873238 D Operon 411 Gene 3 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 872651..873238 Streptococcus pneumoniae AP200 9726930 YP_003876507.1 CDS SPAP_0916 NC_014494.1 873298 873534 D Operon 411 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 873298..873534 Streptococcus pneumoniae AP200 9726931 YP_003876508.1 CDS SPAP_0917 NC_014494.1 873531 873944 D Operon 411 Gene 5 COG3654 Prophage maintenance system killer protein; prophage maintenance system killer protein 873531..873944 Streptococcus pneumoniae AP200 9726932 YP_003876509.1 CDS SPAP_0918 NC_014494.1 874062 875027 D Operon 412 Gene 1 COG0582 Integrase; integrase 874062..875027 Streptococcus pneumoniae AP200 9726933 YP_003876510.1 CDS SPAP_0919 NC_014494.1 875050 875631 D Operon 412 Gene 2 COG0732 Restriction endonuclease S subunits; restriction endonuclease S subunit 875050..875631 Streptococcus pneumoniae AP200 9726934 YP_003876511.1 CDS SPAP_0920 NC_014494.1 875661 879011 D Operon 412 Gene 3 COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases; type I site-specific restriction-modification system protein R 875661..879011 Streptococcus pneumoniae AP200 9726935 YP_003876512.1 CDS SPAP_0921 NC_014494.1 879307 879552 D Operon 413 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 879307..879552 Streptococcus pneumoniae AP200 9726936 YP_003876513.1 CDS SPAP_0922 NC_014494.1 879646 880116 R Operon 414 Gene 1 COG1438 Arginine repressor; arginine repressor complement(879646..880116) Streptococcus pneumoniae AP200 9726937 YP_003876514.1 CDS SPAP_0923 NC_014494.1 880133 882406 R Operon 414 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(880133..882406) Streptococcus pneumoniae AP200 9726938 YP_003876515.1 CDS SPAP_0924 NC_014494.1 882753 885854 D Operon 415 Gene 1 COG0587 DNA polymerase III, alpha subunit; DNA polymerase III subunit alpha 882753..885854 Streptococcus pneumoniae AP200 9726939 YP_003876516.1 CDS SPAP_0925 NC_014494.1 885937 886944 D Operon 415 Gene 2 COG0205 6-phosphofructokinase; 6-phosphofructokinase 885937..886944 Streptococcus pneumoniae AP200 9726940 YP_003876517.1 CDS SPAP_0926 NC_014494.1 887003 888508 D Operon 415 Gene 3 COG0469 Pyruvate kinase; pyruvate kinase 887003..888508 Streptococcus pneumoniae AP200 9726941 YP_003876518.1 CDS SPAP_0927 NC_014494.1 888686 888928 R Operon 416 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(888686..888928) Streptococcus pneumoniae AP200 9726942 YP_003876519.1 CDS SPAP_0928 NC_014494.1 889582 889728 R Operon 417 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(889582..889728) Streptococcus pneumoniae AP200 9726943 YP_003876520.1 CDS SPAP_0929 NC_014494.1 890272 891144 D Operon 418 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 890272..891144 Streptococcus pneumoniae AP200 9726944 YP_003876521.1 CDS SPAP_0930 NC_014494.1 891251 891634 R transposase-like protein, IS1381 ISSpn7 complement(891251..891634) Streptococcus pneumoniae AP200 9726945 YP_003876522.1 CDS SPAP_0931 NC_014494.1 891777 892088 D Operon 420 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 891777..892088 Streptococcus pneumoniae AP200 9726946 YP_003876523.1 CDS SPAP_0932 NC_014494.1 892092 892808 D Operon 420 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 892092..892808 Streptococcus pneumoniae AP200 9726947 YP_003876524.1 CDS SPAP_0933 NC_014494.1 892937 893752 R Operon 421 Gene 1 COG3689 Predicted membrane protein; hypothetical protein complement(892937..893752) Streptococcus pneumoniae AP200 9726948 YP_003876525.1 CDS SPAP_0934 NC_014494.1 893749 894654 R Operon 421 Gene 2 COG0701 Predicted permeases; putative permease complement(893749..894654) Streptococcus pneumoniae AP200 9726949 YP_003876526.1 CDS SPAP_0935 NC_014494.1 894655 894786 R Operon 421 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(894655..894786) Streptococcus pneumoniae AP200 9726950 YP_003876527.1 CDS SPAP_0936 NC_014494.1 894674 894805 D Operon 422 Gene 1 protein supported gi|148998378|ref|ZP_01825820.1| 50S ribosomal protein L21; hypothetical protein 894674..894805 Streptococcus pneumoniae AP200 9726951 YP_003876528.1 CDS SPAP_0937 NC_014494.1 895066 897195 D Operon 423 Gene 1 COG2183 Transcriptional accessory protein; transcriptional accessory protein 895066..897195 Streptococcus pneumoniae AP200 9726952 YP_003876529.1 CDS SPAP_0938 NC_014494.1 897182 897631 D Operon 423 Gene 2 COG3091 Uncharacterized protein conserved in bacteria; hypothetical protein 897182..897631 Streptococcus pneumoniae AP200 9726953 YP_003876530.1 CDS SPAP_0939 NC_014494.1 897690 897962 D Operon 423 Gene 3 COG1983 Putative stress-responsive transcriptional regulator; putative stress-responsive transcriptional regulator 897690..897962 Streptococcus pneumoniae AP200 9726954 YP_003876531.1 CDS SPAP_0940 NC_014494.1 898317 898508 R Operon 424 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(898317..898508) Streptococcus pneumoniae AP200 9726955 YP_003876532.1 CDS SPAP_0941 NC_014494.1 898811 898921 D Operon 425 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 898811..898921 Streptococcus pneumoniae AP200 9726956 YP_003876533.1 CDS SPAP_0942 NC_014494.1 898936 899694 D Operon 425 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 898936..899694 Streptococcus pneumoniae AP200 9726957 YP_003876534.1 CDS SPAP_0943 NC_014494.1 899696 901684 D Operon 425 Gene 3 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease 899696..901684 Streptococcus pneumoniae AP200 9726958 YP_003876535.1 CDS SPAP_0944 NC_014494.1 901726 902316 R Operon 426 Gene 1 COG1814 Uncharacterized membrane protein; hypothetical protein complement(901726..902316) Streptococcus pneumoniae AP200 9726959 YP_003876536.1 CDS SPAP_0945 NC_014494.1 902342 902869 R transposase-like protein, IS1239 complement(902342..902869) Streptococcus pneumoniae AP200 9726960 YP_003876537.1 CDS SPAP_0946 NC_014494.1 902856 903440 R transposase-like protein, IS1239 complement(902856..903440) Streptococcus pneumoniae AP200 9726961 YP_003876538.1 CDS SPAP_0947 NC_014494.1 904055 905530 D Operon 427 Gene 1 COG1982 Arginine/lysine/ornithine decarboxylases; arginine/lysine/ornithine decarboxylase 904055..905530 Streptococcus pneumoniae AP200 9726962 YP_003876539.1 CDS SPAP_0948 NC_014494.1 905874 906527 R Operon 428 Gene 1 COG3547 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_1 complement(905874..906527) Streptococcus pneumoniae AP200 9726963 YP_003876540.1 CDS SPAP_0949 NC_014494.1 906644 906766 R transposase-like protein, ISSpn_AP200_1 complement(906644..906766) Streptococcus pneumoniae AP200 9726964 YP_003876541.1 CDS SPAP_0950 NC_014494.1 907022 907882 D Operon 430 Gene 1 COG0421 Spermidine synthase; spermidine synthase 907022..907882 Streptococcus pneumoniae AP200 9726965 YP_003876542.1 CDS SPAP_0951 NC_014494.1 907879 909138 D Operon 430 Gene 2 COG1748 Saccharopine dehydrogenase and related proteins; Saccharopine dehydrogenase-like protein 907879..909138 Streptococcus pneumoniae AP200 9726966 YP_003876543.1 CDS SPAP_0952 NC_014494.1 909138 910265 D Operon 430 Gene 3 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase 909138..910265 Streptococcus pneumoniae AP200 9726967 YP_003876544.1 CDS SPAP_0953 NC_014494.1 910262 911347 D Operon 430 Gene 4 COG2957 Peptidylarginine deiminase and related enzymes; peptidylarginine deiminase-like enzyme 910262..911347 Streptococcus pneumoniae AP200 9726968 YP_003876545.1 CDS SPAP_0954 NC_014494.1 911357 912232 D Operon 430 Gene 5 COG0388 Predicted amidohydrolase; putative amidohydrolase 911357..912232 Streptococcus pneumoniae AP200 9726969 YP_003876546.1 CDS SPAP_0955 NC_014494.1 912413 913222 R Operon 431 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(912413..913222) Streptococcus pneumoniae AP200 9726970 YP_003876547.1 CDS SPAP_0956 NC_014494.1 913494 913715 D Operon 432 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 913494..913715 Streptococcus pneumoniae AP200 9726971 YP_003876548.1 CDS SPAP_0957 NC_014494.1 913769 914440 D Operon 432 Gene 2 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease 913769..914440 Streptococcus pneumoniae AP200 9726972 YP_003876549.1 CDS SPAP_0958 NC_014494.1 914491 914688 R Operon 433 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein complement(914491..914688) Streptococcus pneumoniae AP200 9726973 YP_003876550.1 CDS SPAP_0959 NC_014494.1 914681 915589 D Operon 434 Gene 1 COG0583 Transcriptional regulator; transcriptional regulator 914681..915589 Streptococcus pneumoniae AP200 9726974 YP_003876551.1 CDS SPAP_0960 NC_014494.1 915586 916047 D Operon 434 Gene 2 COG0597 Lipoprotein signal peptidase; lipoprotein signal peptidase 915586..916047 Streptococcus pneumoniae AP200 9726975 YP_003876552.1 CDS SPAP_0961 NC_014494.1 916037 916924 D Operon 434 Gene 3 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 916037..916924 Streptococcus pneumoniae AP200 9726976 YP_003876553.1 CDS SPAP_0962 NC_014494.1 916927 918822 D Operon 434 Gene 4 COG5263 FOG: Choline binding protein E CbpE; choline binding protein E CbpE 916927..918822 Streptococcus pneumoniae AP200 9726977 YP_003876554.1 CDS SPAP_0963 NC_014494.1 918923 920032 D Operon 435 Gene 1 COG0263 Glutamate 5-kinase; glutamate 5-kinase 918923..920032 Streptococcus pneumoniae AP200 9726978 YP_003876555.1 CDS SPAP_0964 NC_014494.1 920042 921304 D Operon 435 Gene 2 COG0014 Gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase 920042..921304 Streptococcus pneumoniae AP200 9726979 YP_003876556.1 CDS SPAP_0965 NC_014494.1 921308 922105 D Operon 435 Gene 3 COG0345 Pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 921308..922105 Streptococcus pneumoniae AP200 9726980 YP_003876557.1 CDS SPAP_0966 NC_014494.1 922325 922963 D Operon 436 Gene 1 COG0125 Thymidylate kinase; thymidylate kinase 922325..922963 Streptococcus pneumoniae AP200 9726981 YP_003876558.1 CDS SPAP_0967 NC_014494.1 922960 923850 D Operon 436 Gene 2 COG0470 ATPase involved in DNA replication; DNA replication ATPase 922960..923850 Streptococcus pneumoniae AP200 9726982 YP_003876559.1 CDS SPAP_0968 NC_014494.1 923890 924207 D Operon 436 Gene 3 COG4467 Uncharacterized protein conserved in bacteria; hypothetical protein 923890..924207 Streptococcus pneumoniae AP200 9726983 YP_003876560.1 CDS SPAP_0969 NC_014494.1 924210 925079 D Operon 436 Gene 4 COG0313 Predicted methyltransferases; putative methyltransferase 924210..925079 Streptococcus pneumoniae AP200 9726984 YP_003876561.1 CDS SPAP_0970 NC_014494.1 925306 925824 D Operon 437 Gene 1 COG4283 Uncharacterized conserved protein; hypothetical protein 925306..925824 Streptococcus pneumoniae AP200 9726985 YP_003876562.1 CDS SPAP_0971 NC_014494.1 925933 926070 D Operon 438 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 925933..926070 Streptococcus pneumoniae AP200 9726986 YP_003876563.1 CDS SPAP_0972 NC_014494.1 926077 926577 D Operon 438 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 926077..926577 Streptococcus pneumoniae AP200 9726987 YP_003876564.1 CDS SPAP_0973 NC_014494.1 926574 926963 R transposase-like protein, IS1381 ISSpn7 complement(926574..926963) Streptococcus pneumoniae AP200 9726988 YP_003876565.1 CDS SPAP_0974 NC_014494.1 927048 927383 R transposase-like protein, IS1381 ISSpn7 complement(927048..927383) Streptococcus pneumoniae AP200 9726989 YP_003876566.1 CDS SPAP_0975 NC_014494.1 927877 929211 D Operon 440 Gene 1 COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; NAD(FAD)-utilizing enzyme possibly involved in translation 927877..929211 Streptococcus pneumoniae AP200 9726990 YP_003876567.1 CDS SPAP_0976 NC_014494.1 929295 930032 D Operon 440 Gene 2 COG0528 Uridylate kinase; Uridylate kinase 929295..930032 Streptococcus pneumoniae AP200 9726991 YP_003876568.1 CDS SPAP_0977 NC_014494.1 930041 930598 D Operon 440 Gene 3 COG0233 Ribosome recycling factor; ribosome recycling factor 930041..930598 Streptococcus pneumoniae AP200 9726992 YP_003876569.1 CDS SPAP_0978 NC_014494.1 930619 931512 D Operon 440 Gene 4 COG2996 Uncharacterized protein conserved in bacteria; hypothetical protein 930619..931512 Streptococcus pneumoniae AP200 9726993 YP_003876570.1 CDS SPAP_0979 NC_014494.1 931548 931736 D Operon 440 Gene 5 COG4479 Uncharacterized protein conserved in bacteria; hypothetical protein 931548..931736 Streptococcus pneumoniae AP200 9726994 YP_003876571.1 CDS SPAP_0980 NC_014494.1 931822 932790 D Operon 441 Gene 1 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase; phosphate starvation-inducible protein PhoH 931822..932790 Streptococcus pneumoniae AP200 9726995 YP_003876572.1 CDS SPAP_0981 NC_014494.1 932983 933483 D Operon 442 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 932983..933483 Streptococcus pneumoniae AP200 9726996 YP_003876573.1 CDS SPAP_0982 NC_014494.1 933486 933713 D Operon 442 Gene 2 COG3070 Regulator of competence-specific genes; regulator of competence-specific genes 933486..933713 Streptococcus pneumoniae AP200 9726997 YP_003876574.1 CDS SPAP_0983 NC_014494.1 934113 934388 R Operon 443 Gene 1 COG0686 Alanine dehydrogenase; alanine dehydrogenase complement(934113..934388) Streptococcus pneumoniae AP200 9726998 YP_003876575.1 CDS SPAP_0984 NC_014494.1 934385 934573 R Operon 443 Gene 2 COG0686 Alanine dehydrogenase; alanine dehydrogenase complement(934385..934573) Streptococcus pneumoniae AP200 9726999 YP_003876576.1 CDS SPAP_0985 NC_014494.1 934799 935224 R Operon 444 Gene 1 COG0686 Alanine dehydrogenase; alanine dehydrogenase complement(934799..935224) Streptococcus pneumoniae AP200 9727000 YP_003876577.1 CDS SPAP_0986 NC_014494.1 935401 935970 D Operon 445 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase 935401..935970 Streptococcus pneumoniae AP200 9727001 YP_003876578.1 CDS SPAP_0987 NC_014494.1 936038 936688 D Operon 445 Gene 2 COG1555 DNA uptake protein and related DNA-binding proteins; DNA uptake protein-like DNA-binding protein 936038..936688 Streptococcus pneumoniae AP200 9727002 YP_003876579.1 CDS SPAP_0988 NC_014494.1 936672 938912 D Operon 445 Gene 3 COG0658 Predicted membrane metal-binding protein; putative membrane metal-binding protein 936672..938912 Streptococcus pneumoniae AP200 9727003 YP_003876580.1 CDS SPAP_0989 NC_014494.1 939311 939898 D Operon 446 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 939311..939898 Streptococcus pneumoniae AP200 9727004 YP_003876581.1 CDS SPAP_0990 NC_014494.1 939902 941083 D Operon 446 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 939902..941083 Streptococcus pneumoniae AP200 9727005 YP_003876582.1 CDS SPAP_0991 NC_014494.1 941390 941920 D Operon 447 Gene 1 protein supported gi|163801060|ref|ZP_02194960.1| 50S ribosomal protein L35; hypothetical protein 941390..941920 Streptococcus pneumoniae AP200 9727006 YP_003876583.1 CDS SPAP_0992 NC_014494.1 941953 942153 D Operon 447 Gene 2 protein supported gi|15900837|ref|NP_345441.1| 50S ribosomal protein L35; hypothetical protein 941953..942153 Streptococcus pneumoniae AP200 9727007 YP_003876584.1 CDS SPAP_0993 NC_014494.1 942205 942564 D Operon 447 Gene 3 protein supported gi|15900838|ref|NP_345442.1| 50S ribosomal protein L20; hypothetical protein 942205..942564 Streptococcus pneumoniae AP200 9727008 YP_003876585.1 CDS SPAP_0994 NC_014494.1 942622 943002 D Operon 447 Gene 4 protein supported gi|15900839|ref|NP_345443.1| lactoylglutathione lyase; hypothetical protein 942622..943002 Streptococcus pneumoniae AP200 9727009 YP_003876586.1 CDS SPAP_0995 NC_014494.1 943252 944052 D Operon 448 Gene 1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases; 2-polyprenylphenol 6-hydroxylase 943252..944052 Streptococcus pneumoniae AP200 9727010 YP_003876587.1 CDS SPAP_0996 NC_014494.1 944063 945001 D Operon 448 Gene 2 COG0167 Dihydroorotate dehydrogenase; dihydroorotate dehydrogenase 944063..945001 Streptococcus pneumoniae AP200 9727011 YP_003876588.1 CDS SPAP_0997 NC_014494.1 945100 946944 D Operon 448 Gene 3 COG5263 FOG: endo-beta-N-acetylglucosaminidase LytB; endo-beta-N-acetylglucosaminidase LytB 945100..946944 Streptococcus pneumoniae AP200 9727012 YP_003876589.1 CDS SPAP_0998 NC_014494.1 947005 948660 R Operon 449 Gene 1 COG1293 Predicted RNA-binding protein homologous to eukaryotic snRNP; putative RNA-binding protein complement(947005..948660) Streptococcus pneumoniae AP200 9727013 YP_003876590.1 CDS SPAP_0999 NC_014494.1 948765 949262 D Operon 450 Gene 1 COG0319 Predicted metal-dependent hydrolase; putative metal-dependent hydrolase 948765..949262 Streptococcus pneumoniae AP200 9727014 YP_003876591.1 CDS SPAP_1000 NC_014494.1 949243 949638 D Operon 450 Gene 2 COG0818 Diacylglycerol kinase; diacylglycerol kinase 949243..949638 Streptococcus pneumoniae AP200 9727015 YP_003876592.1 CDS SPAP_1001 NC_014494.1 949655 950554 D Operon 450 Gene 3 COG1159 GTPase; GTPase 949655..950554 Streptococcus pneumoniae AP200 9727016 YP_003876593.1 CDS SPAP_1002 NC_014494.1 950603 951427 D Operon 450 Gene 4 COG0266 Formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase 950603..951427 Streptococcus pneumoniae AP200 9727017 YP_003876594.1 CDS SPAP_1003 NC_014494.1 951427 952032 D Operon 450 Gene 5 COG0237 Dephospho-CoA kinase; dephospho-CoA kinase 951427..952032 Streptococcus pneumoniae AP200 9727018 YP_003876595.1 CDS SPAP_1004 NC_014494.1 951916 952116 R Operon 451 Gene 1 protein supported gi|15902918|ref|NP_358468.1| hypothetical protein spr0874; hypothetical protein complement(951916..952116) Streptococcus pneumoniae AP200 9727019 YP_003876596.1 CDS SPAP_1005 NC_014494.1 952019 953218 D Operon 452 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease 952019..953218 Streptococcus pneumoniae AP200 9727020 YP_003876597.1 CDS SPAP_1006 NC_014494.1 953218 953367 D Operon 452 Gene 2 protein supported gi|15902920|ref|NP_358470.1| 50S ribosomal protein L33; hypothetical protein 953218..953367 Streptococcus pneumoniae AP200 9727021 YP_003876598.1 CDS SPAP_1007 NC_014494.1 953407 953640 D Operon 452 Gene 3 COG1314 Preprotein translocase subunit SecG; preprotein translocase subunit SecG 953407..953640 Streptococcus pneumoniae AP200 9727022 YP_003876599.1 CDS SPAP_1008 NC_014494.1 953742 956096 D Operon 453 Gene 1 COG0557 Exoribonuclease R; exoribonuclease R 953742..956096 Streptococcus pneumoniae AP200 9727023 YP_003876600.1 CDS SPAP_1009 NC_014494.1 956059 956526 D Operon 453 Gene 2 COG0691 tmRNA-binding protein; tmRNA-binding protein 956059..956526 Streptococcus pneumoniae AP200 9727024 YP_003876601.1 CDS SPAP_1010 NC_014494.1 956542 957402 D Operon 453 Gene 3 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 956542..957402 Streptococcus pneumoniae AP200 9727025 YP_003876602.1 CDS SPAP_1011 NC_014494.1 957475 958428 D Operon 454 Gene 1 COG4469 Competence protein; competence protein 957475..958428 Streptococcus pneumoniae AP200 9727026 YP_003876603.1 CDS SPAP_1012 NC_014494.1 958447 960249 D Operon 454 Gene 2 COG1164 Oligoendopeptidase F; oligoendopeptidase F 958447..960249 Streptococcus pneumoniae AP200 9727027 YP_003876604.1 CDS SPAP_1013 NC_014494.1 960251 960964 D Operon 454 Gene 3 COG4122 Predicted O-methyltransferase; putative O-methyltransferase 960251..960964 Streptococcus pneumoniae AP200 9727028 YP_003876605.1 CDS SPAP_1014 NC_014494.1 961031 961348 D Operon 454 Gene 4 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961031..961348 Streptococcus pneumoniae AP200 9727029 YP_003876606.1 CDS SPAP_1015 NC_014494.1 961239 961619 D Operon 454 Gene 5 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961239..961619 Streptococcus pneumoniae AP200 9727030 YP_003876607.1 CDS SPAP_1016 NC_014494.1 961675 961974 D Operon 454 Gene 6 COG0760 Parvulin-like peptidyl-prolyl isomerase; parvulin-like peptidyl-prolyl isomerase 961675..961974 Streptococcus pneumoniae AP200 9727031 YP_003876608.1 CDS SPAP_1017 NC_014494.1 962093 962434 R Operon 455 Gene 1 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 complement(962093..962434) Streptococcus pneumoniae AP200 9727032 YP_003876609.1 CDS SPAP_1018 NC_014494.1 962434 962625 R Operon 455 Gene 2 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 complement(962434..962625) Streptococcus pneumoniae AP200 9727033 YP_003876610.1 CDS SPAP_1019 NC_014494.1 962714 962944 R Operon 456 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(962714..962944) Streptococcus pneumoniae AP200 9727034 YP_003876611.1 CDS SPAP_1020 NC_014494.1 963196 963816 R Operon 457 Gene 1 COG0406 Fructose-2,6-bisphosphatase; fructose-2,6-bisphosphatase complement(963196..963816) Streptococcus pneumoniae AP200 9727035 YP_003876612.1 CDS SPAP_1021 NC_014494.1 963816 964298 R Operon 457 Gene 2 COG2606 Uncharacterized conserved protein; hypothetical protein complement(963816..964298) Streptococcus pneumoniae AP200 9727036 YP_003876613.1 CDS SPAP_1022 NC_014494.1 964298 965140 R Operon 457 Gene 3 COG2035 Predicted membrane protein; hypothetical protein complement(964298..965140) Streptococcus pneumoniae AP200 9727037 YP_003876614.1 CDS SPAP_1023 NC_014494.1 965235 966035 R Operon 457 Gene 4 COG3757 Lyzozyme M1 (1,4-beta-N-acetylmuramidase); lyzozyme M1 (1,4-beta-N-acetylmuramidase) complement(965235..966035) Streptococcus pneumoniae AP200 9727038 YP_003876615.1 CDS SPAP_1024 NC_014494.1 966179 967558 D Operon 458 Gene 1 COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); N-acetylglucosamine-1-phosphate uridyltransferase 966179..967558 Streptococcus pneumoniae AP200 9727039 YP_003876616.1 CDS SPAP_1025 NC_014494.1 967568 968113 D Operon 458 Gene 2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 967568..968113 Streptococcus pneumoniae AP200 9727040 YP_003876617.1 CDS SPAP_1026 NC_014494.1 968125 968439 D Operon 458 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 968125..968439 Streptococcus pneumoniae AP200 9727041 YP_003876618.1 CDS SPAP_1027 NC_014494.1 968456 969148 D Operon 458 Gene 4 COG0775 Nucleoside phosphorylase; nucleoside phosphorylase 968456..969148 Streptococcus pneumoniae AP200 9727042 YP_003876619.1 CDS SPAP_1028 NC_014494.1 969225 969716 D Operon 458 Gene 5 Putative gene predicted by FgenesB; hypothetical protein 969225..969716 Streptococcus pneumoniae AP200 9727043 YP_003876620.1 CDS SPAP_1029 NC_014494.1 969814 970404 D Operon 459 Gene 1 COG0847 DNA polymerase III, epsilon subunit and related 3'-5' exonucleases; DNA polymerase III subunit epsilon-like 3'-5' exonuclease 969814..970404 Streptococcus pneumoniae AP200 9727044 YP_003876621.1 CDS SPAP_1030 NC_014494.1 970413 972176 D Operon 459 Gene 2 COG4781 Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase; glycerophosphoryl diester phosphodiesterase 970413..972176 Streptococcus pneumoniae AP200 9727045 YP_003876622.1 CDS SPAP_1031 NC_014494.1 972372 972755 D transposase-like protein, IS630 972372..972755 Streptococcus pneumoniae AP200 9727046 YP_003876623.1 CDS SPAP_1032 NC_014494.1 972761 973021 R Operon 461 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(972761..973021) Streptococcus pneumoniae AP200 9727047 YP_003876624.1 CDS SPAP_1033 NC_014494.1 973202 973402 D Operon 462 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 973202..973402 Streptococcus pneumoniae AP200 9727048 YP_003876625.1 CDS SPAP_1034 NC_014494.1 973439 973843 D Operon 462 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 973439..973843 Streptococcus pneumoniae AP200 9727049 YP_003876626.1 CDS SPAP_1035 NC_014494.1 974208 974780 D Operon 463 Gene 1 COG0785 Cytochrome c biogenesis protein; cytochrome c biogenesis protein 974208..974780 Streptococcus pneumoniae AP200 9727050 YP_003876627.1 CDS SPAP_1036 NC_014494.1 974791 975348 D Operon 463 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 974791..975348 Streptococcus pneumoniae AP200 9727051 YP_003876628.1 CDS SPAP_1037 NC_014494.1 975722 977113 D Operon 464 Gene 1 COG0531 Amino acid transporters; amino acid transporter 975722..977113 Streptococcus pneumoniae AP200 9727052 YP_003876629.1 CDS SPAP_1038 NC_014494.1 977256 978173 D Operon 465 Gene 1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin 977256..978173 Streptococcus pneumoniae AP200 9727053 YP_003876630.1 CDS SPAP_1039 NC_014494.1 978181 979050 D Operon 465 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 978181..979050 Streptococcus pneumoniae AP200 9727054 YP_003876631.1 CDS SPAP_1040 NC_014494.1 979017 979736 D Operon 465 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 979017..979736 Streptococcus pneumoniae AP200 9727055 YP_003876632.1 CDS SPAP_1041 NC_014494.1 979724 980659 D Operon 465 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 979724..980659 Streptococcus pneumoniae AP200 9727056 YP_003876633.1 CDS SPAP_1042 NC_014494.1 981081 981461 D Operon 466 Gene 1 COG3412 Uncharacterized protein conserved in bacteria; hypothetical protein 981081..981461 Streptococcus pneumoniae AP200 9727057 YP_003876634.1 CDS SPAP_1043 NC_014494.1 981920 982633 D Operon 467 Gene 1 COG1011 Predicted hydrolase (HAD superfamily); putative HD superfamily hydrolase 981920..982633 Streptococcus pneumoniae AP200 9727058 YP_003876635.1 CDS SPAP_1044 NC_014494.1 982691 983293 D Operon 467 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 982691..983293 Streptococcus pneumoniae AP200 9727059 YP_003876636.1 CDS SPAP_1045 NC_014494.1 983429 984082 D Operon 468 Gene 1 COG0692 Uracil DNA glycosylase; Uracil DNA glycosylase 983429..984082 Streptococcus pneumoniae AP200 9727060 YP_003876637.1 CDS SPAP_1046 NC_014494.1 984092 984556 D Operon 468 Gene 2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes 984092..984556 Streptococcus pneumoniae AP200 9727061 YP_003876638.1 CDS SPAP_1047 NC_014494.1 984569 985837 D Operon 468 Gene 3 COG0044 Dihydroorotase and related cyclic amidohydrolases; dihydroorotase-like cyclic amidohydrolase 984569..985837 Streptococcus pneumoniae AP200 9727062 YP_003876639.1 CDS SPAP_1048 NC_014494.1 985851 986111 D Operon 468 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 985851..986111 Streptococcus pneumoniae AP200 9727063 YP_003876640.1 CDS SPAP_1049 NC_014494.1 986122 987483 D Operon 468 Gene 5 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump 986122..987483 Streptococcus pneumoniae AP200 9727064 YP_003876641.1 CDS SPAP_1050 NC_014494.1 987637 988605 D Operon 469 Gene 1 COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit; pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit alpha 987637..988605 Streptococcus pneumoniae AP200 9727065 YP_003876642.1 CDS SPAP_1051 NC_014494.1 988636 989613 D Operon 469 Gene 2 COG0022 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit; pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component subunit beta 988636..989613 Streptococcus pneumoniae AP200 9727066 YP_003876643.1 CDS SPAP_1052 NC_014494.1 989831 990874 D Operon 470 Gene 1 COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component-like protein 989831..990874 Streptococcus pneumoniae AP200 9727067 YP_003876644.1 CDS SPAP_1053 NC_014494.1 990920 992623 D Operon 470 Gene 2 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein 990920..992623 Streptococcus pneumoniae AP200 9727068 YP_003876645.1 CDS SPAP_1054 NC_014494.1 992687 993676 D Operon 470 Gene 3 COG0095 Lipoate-protein ligase A; lipoate-protein ligase A 992687..993676 Streptococcus pneumoniae AP200 9727069 YP_003876646.1 CDS SPAP_1055 NC_014494.1 993749 994819 R Operon 471 Gene 1 COG0582 Integrase; integrase complement(993749..994819) Streptococcus pneumoniae AP200 9727070 YP_003876647.1 CDS SPAP_1056 NC_014494.1 995403 996953 R Operon 472 Gene 1 COG0038 Chloride channel protein EriC; chloride channel protein EriC complement(995403..996953) Streptococcus pneumoniae AP200 9727071 YP_003876648.1 CDS SPAP_1057 NC_014494.1 996969 997748 R Operon 472 Gene 2 COG0164 Ribonuclease HII; ribonuclease HII complement(996969..997748) Streptococcus pneumoniae AP200 9727072 YP_003876649.1 CDS SPAP_1058 NC_014494.1 997735 998586 R Operon 472 Gene 3 COG1161 Predicted GTPases; putative GTPase complement(997735..998586) Streptococcus pneumoniae AP200 9727073 YP_003876650.1 CDS SPAP_1059 NC_014494.1 999021 1004648 R immunoglobulin A1 protease; hypothetical protein complement(999021..1004648) Streptococcus pneumoniae AP200 9727074 YP_003876651.1 CDS SPAP_1060 NC_014494.1 1004857 1006035 R Operon 474 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1004857..1006035) Streptococcus pneumoniae AP200 9727075 YP_003876652.1 CDS SPAP_1061 NC_014494.1 1006430 1010080 R Operon 475 Gene 1 COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit; contains helicase and exonuclease domains; ATP-dependent exoDNAse (exonuclease V) subunit beta complement(1006430..1010080) Streptococcus pneumoniae AP200 9727076 YP_003876653.1 CDS SPAP_1062 NC_014494.1 1010077 1013376 R Operon 475 Gene 2 COG3857 ATP-dependent nuclease, subunit B; ATP-dependent nuclease subunit B complement(1010077..1013376) Streptococcus pneumoniae AP200 9727077 YP_003876654.1 CDS SPAP_1063 NC_014494.1 1013860 1014207 D transposase-like protein, IS630 1013860..1014207 Streptococcus pneumoniae AP200 9727078 YP_003876655.1 CDS SPAP_1064 NC_014494.1 1014542 1014724 D Operon 477 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 1014542..1014724 Streptococcus pneumoniae AP200 9727079 YP_003876656.1 CDS SPAP_1065 NC_014494.1 1015208 1016512 R Operon 478 Gene 1 COG0148 Enolase; enolase complement(1015208..1016512) Streptococcus pneumoniae AP200 9727080 YP_003876657.1 CDS SPAP_1066 NC_014494.1 1016676 1017122 D Operon 479 Gene 1 COG5506 Uncharacterized conserved protein; hypothetical protein 1016676..1017122 Streptococcus pneumoniae AP200 9727081 YP_003876658.1 CDS SPAP_1067 NC_014494.1 1017119 1018234 R Operon 480 Gene 1 COG1929 Glycerate kinase; glycerate kinase complement(1017119..1018234) Streptococcus pneumoniae AP200 9727082 YP_003876659.1 CDS SPAP_1068 NC_014494.1 1018243 1018572 R Operon 480 Gene 2 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase complement(1018243..1018572) Streptococcus pneumoniae AP200 9727083 YP_003876660.1 CDS SPAP_1069 NC_014494.1 1018517 1018888 R Operon 480 Gene 3 COG0560 Phosphoserine phosphatase; phosphoserine phosphatase complement(1018517..1018888) Streptococcus pneumoniae AP200 9727084 YP_003876661.1 CDS SPAP_1070 NC_014494.1 1018947 1020380 R Operon 481 Gene 1 COG0297 Glycogen synthase; glycogen synthase complement(1018947..1020380) Streptococcus pneumoniae AP200 9727085 YP_003876662.1 CDS SPAP_1071 NC_014494.1 1020377 1021516 R Operon 481 Gene 2 COG0448 ADP-glucose pyrophosphorylase; ADP-glucose pyrophosphorylase complement(1020377..1021516) Streptococcus pneumoniae AP200 9727086 YP_003876663.1 CDS SPAP_1072 NC_014494.1 1021506 1022648 R Operon 481 Gene 3 COG0448 ADP-glucose pyrophosphorylase; ADP-glucose pyrophosphorylase complement(1021506..1022648) Streptococcus pneumoniae AP200 9727087 YP_003876664.1 CDS SPAP_1073 NC_014494.1 1022638 1024566 R Operon 481 Gene 4 COG0296 1,4-alpha-glucan branching enzyme; 1,4-alpha-glucan branching enzyme complement(1022638..1024566) Streptococcus pneumoniae AP200 9727088 YP_003876665.1 CDS SPAP_1074 NC_014494.1 1024942 1026366 R Operon 482 Gene 1 COG1012 NAD-dependent aldehyde dehydrogenases; NAD-dependent aldehyde dehydrogenase complement(1024942..1026366) Streptococcus pneumoniae AP200 9727089 YP_003876666.1 CDS SPAP_1075 NC_014494.1 1026911 1029190 R Operon 483 Gene 1 COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; type II secretory pathway pullulanase PulA-like glycosidase complement(1026911..1029190) Streptococcus pneumoniae AP200 9727090 YP_003876667.1 CDS SPAP_1076 NC_014494.1 1029302 1031248 R Operon 483 Gene 2 COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); NAD-dependent DNA ligase (contains BRCT domain type II) complement(1029302..1031248) Streptococcus pneumoniae AP200 9727091 YP_003876668.1 CDS SPAP_1077 NC_014494.1 1031353 1032531 R Operon 484 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(1031353..1032531) Streptococcus pneumoniae AP200 9727092 YP_003876669.1 CDS SPAP_1078 NC_014494.1 1032611 1033474 R Operon 484 Gene 2 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1032611..1033474) Streptococcus pneumoniae AP200 9727093 YP_003876670.1 CDS SPAP_1079 NC_014494.1 1033477 1035378 R Operon 484 Gene 3 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase complement(1033477..1035378) Streptococcus pneumoniae AP200 9727094 YP_003876671.1 CDS SPAP_1080 NC_014494.1 1035803 1036078 R Operon 485 Gene 1 COG0776 Bacterial nucleoid DNA-binding protein; nucleoid DNA-binding protein complement(1035803..1036078) Streptococcus pneumoniae AP200 9727095 YP_003876672.1 CDS SPAP_1081 NC_014494.1 1036184 1037023 R Operon 485 Gene 2 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1036184..1037023) Streptococcus pneumoniae AP200 9727096 YP_003876673.1 CDS SPAP_1082 NC_014494.1 1037165 1038013 D Operon 486 Gene 1 COG1284 Uncharacterized conserved protein; hypothetical protein 1037165..1038013 Streptococcus pneumoniae AP200 9727097 YP_003876674.1 CDS SPAP_1083 NC_014494.1 1038106 1039023 R Operon 487 Gene 1 COG0196 FAD synthase; FAD synthase complement(1038106..1039023) Streptococcus pneumoniae AP200 9727098 YP_003876675.1 CDS SPAP_1084 NC_014494.1 1039312 1039482 R Operon 488 Gene 1 protein supported gi|148998378|ref|ZP_01825820.1| 50S ribosomal protein L21; hypothetical protein complement(1039312..1039482) Streptococcus pneumoniae AP200 9727099 YP_003876676.1 CDS SPAP_1085 NC_014494.1 1039458 1039664 D Operon 489 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1039458..1039664 Streptococcus pneumoniae AP200 9727100 YP_003876677.1 CDS SPAP_1086 NC_014494.1 1039975 1040268 R Operon 490 Gene 1 protein supported gi|111658016|ref|ZP_01408720.1| hypothetical protein SpneT_02000813; hypothetical protein complement(1039975..1040268) Streptococcus pneumoniae AP200 9727101 YP_003876678.1 CDS SPAP_1087 NC_014494.1 1040285 1040629 R Operon 490 Gene 2 protein supported gi|15900973|ref|NP_345577.1| hypothetical protein SP_1106; hypothetical protein complement(1040285..1040629) Streptococcus pneumoniae AP200 9727102 YP_003876679.1 CDS SPAP_1088 NC_014494.1 1040645 1040959 R Operon 490 Gene 3 protein supported gi|148985076|ref|ZP_01818319.1| ribosomal protein L21; hypothetical protein complement(1040645..1040959) Streptococcus pneumoniae AP200 9727103 YP_003876680.1 CDS SPAP_1089 NC_014494.1 1041178 1041846 R Operon 491 Gene 1 COG3619 Predicted membrane protein; hypothetical protein complement(1041178..1041846) Streptococcus pneumoniae AP200 9727104 YP_003876681.1 CDS SPAP_1090 NC_014494.1 1042248 1042547 D Operon 492 Gene 1 COG0718 Uncharacterized protein conserved in bacteria; hypothetical protein 1042248..1042547 Streptococcus pneumoniae AP200 9727105 YP_003876682.1 CDS SPAP_1091 NC_014494.1 1042729 1043247 D Operon 493 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 1042729..1043247 Streptococcus pneumoniae AP200 9727106 YP_003876683.1 CDS SPAP_1092 NC_014494.1 1043528 1044055 D Operon 494 Gene 1 COG3464 Transposase and inactivated derivatives; transposase-like protein, IS1167 1043528..1044055 Streptococcus pneumoniae AP200 9727107 YP_003876684.1 CDS SPAP_1093 NC_014494.1 1044316 1045290 R Operon 495 Gene 1 COG0280 Phosphotransacetylase; phosphotransacetylase complement(1044316..1045290) Streptococcus pneumoniae AP200 9727108 YP_003876685.1 CDS SPAP_1094 NC_014494.1 1045334 1046230 R Operon 495 Gene 2 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase complement(1045334..1046230) Streptococcus pneumoniae AP200 9727109 YP_003876686.1 CDS SPAP_1095 NC_014494.1 1046227 1047057 R Operon 495 Gene 3 COG0061 Predicted sugar kinase; putative sugar kinase complement(1046227..1047057) Streptococcus pneumoniae AP200 9727110 YP_003876687.1 CDS SPAP_1096 NC_014494.1 1047029 1047700 R Operon 495 Gene 4 COG2357 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1047029..1047700) Streptococcus pneumoniae AP200 9727111 YP_003876688.1 CDS SPAP_1097 NC_014494.1 1047828 1048397 D Operon 496 Gene 1 COG4116 Uncharacterized protein conserved in bacteria; hypothetical protein 1047828..1048397 Streptococcus pneumoniae AP200 9727112 YP_003876689.1 CDS SPAP_1098 NC_014494.1 1048510 1049469 D Operon 497 Gene 1 COG0462 Phosphoribosylpyrophosphate synthetase; phosphoribosylpyrophosphate synthetase 1048510..1049469 Streptococcus pneumoniae AP200 9727113 YP_003876690.1 CDS SPAP_1099 NC_014494.1 1049479 1050594 D Operon 497 Gene 2 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes; cysteine sulfinate desulfinase/cysteine desulfurase-like protein 1049479..1050594 Streptococcus pneumoniae AP200 9727114 YP_003876691.1 CDS SPAP_1100 NC_014494.1 1050599 1050946 D Operon 497 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1050599..1050946 Streptococcus pneumoniae AP200 9727115 YP_003876692.1 CDS SPAP_1101 NC_014494.1 1050954 1051169 D Operon 497 Gene 4 Putative gene predicted by FgenesB; hypothetical protein 1050954..1051169 Streptococcus pneumoniae AP200 9727116 YP_003876693.1 CDS SPAP_1102 NC_014494.1 1051252 1051893 D Operon 498 Gene 1 COG2344 AT-rich DNA-binding protein; AT-rich DNA-binding protein 1051252..1051893 Streptococcus pneumoniae AP200 9727117 YP_003876694.1 CDS SPAP_1103 NC_014494.1 1051911 1052600 D Operon 498 Gene 2 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase 1051911..1052600 Streptococcus pneumoniae AP200 9727118 YP_003876695.1 CDS SPAP_1104 NC_014494.1 1052597 1053277 R Operon 499 Gene 1 COG2003 DNA repair proteins; DNA repair protein complement(1052597..1053277) Streptococcus pneumoniae AP200 9727119 YP_003876696.1 CDS SPAP_1105 NC_014494.1 1053320 1055611 R Operon 499 Gene 2 COG0210 Superfamily I DNA and RNA helicases; superfamily I DNA and RNA helicase complement(1053320..1055611) Streptococcus pneumoniae AP200 9727120 YP_003876697.1 CDS SPAP_1106 NC_014494.1 1055783 1056268 R transposase-like protein, IS1381 ISSpn7 complement(1055783..1056268) Streptococcus pneumoniae AP200 9727121 YP_003876698.1 CDS SPAP_1107 NC_014494.1 1056210 1056764 R transposase-like protein, IS1381 ISSpn7 complement(1056210..1056764) Streptococcus pneumoniae AP200 9727122 YP_003876699.1 CDS SPAP_1108 NC_014494.1 1056989 1057849 R Operon 501 Gene 1 COG0024 Methionine aminopeptidase; methionine aminopeptidase complement(1056989..1057849) Streptococcus pneumoniae AP200 9727123 YP_003876700.1 CDS SPAP_1109 NC_014494.1 1057865 1059142 R Operon 501 Gene 2 COG4109 Predicted transcriptional regulator containing CBS domains; putative transcriptional regulator complement(1057865..1059142) Streptococcus pneumoniae AP200 9727124 YP_003876701.1 CDS SPAP_1110 NC_014494.1 1059135 1059686 R Operon 501 Gene 3 protein supported gi|116628248|ref|YP_820867.1| GNAT family acetyltransferase; hypothetical protein complement(1059135..1059686) Streptococcus pneumoniae AP200 9727125 YP_003876702.1 CDS SPAP_1111 NC_014494.1 1059702 1060961 R Operon 501 Gene 4 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine enolpyruvyl transferase complement(1059702..1060961) Streptococcus pneumoniae AP200 9727126 YP_003876703.1 CDS SPAP_1112 NC_014494.1 1061104 1061229 D Operon 502 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1061104..1061229 Streptococcus pneumoniae AP200 9727127 YP_003876704.1 CDS SPAP_1113 NC_014494.1 1062104 1062262 R Operon 503 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1062104..1062262) Streptococcus pneumoniae AP200 9727128 YP_003876705.1 CDS SPAP_1114 NC_014494.1 1062272 1063582 R Operon 503 Gene 2 COG0536 Predicted GTPase; putative GTPase complement(1062272..1063582) Streptococcus pneumoniae AP200 9727129 YP_003876706.1 CDS SPAP_1115 NC_014494.1 1063646 1063780 R Operon 503 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1063646..1063780) Streptococcus pneumoniae AP200 9727130 YP_003876707.1 CDS SPAP_1116 NC_014494.1 1063839 1064015 R Operon 503 Gene 4 COG1983 Putative stress-responsive transcriptional regulator; putative stress-responsive transcriptional regulator complement(1063839..1064015) Streptococcus pneumoniae AP200 9727131 YP_003876708.1 CDS SPAP_1117 NC_014494.1 1064046 1065371 R Operon 503 Gene 5 COG0438 Glycosyltransferase; glycosyltransferase complement(1064046..1065371) Streptococcus pneumoniae AP200 9727132 YP_003876709.1 CDS SPAP_1118 NC_014494.1 1065387 1066430 R Operon 503 Gene 6 COG0438 Glycosyltransferase; glycosyltransferase complement(1065387..1066430) Streptococcus pneumoniae AP200 9727133 YP_003876710.1 CDS SPAP_1119 NC_014494.1 1066545 1066874 R Operon 504 Gene 1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; putative metal-sulfur cluster biosynthetic enzyme complement(1066545..1066874) Streptococcus pneumoniae AP200 9727134 YP_003876711.1 CDS SPAP_1120 NC_014494.1 1066888 1067997 R Operon 504 Gene 2 COG0568 DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32); DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) complement(1066888..1067997) Streptococcus pneumoniae AP200 9727135 YP_003876712.1 CDS SPAP_1121 NC_014494.1 1068000 1069760 R Operon 504 Gene 3 COG0358 DNA primase (bacterial type); DNA primase complement(1068000..1069760) Streptococcus pneumoniae AP200 9727136 YP_003876713.1 CDS SPAP_1122 NC_014494.1 1069869 1070501 R transposase-like protein, IS1239 complement(1069869..1070501) Streptococcus pneumoniae AP200 9727137 YP_003876714.1 CDS SPAP_1123 NC_014494.1 1070651 1070821 R transposase-like protein, IS1239 complement(1070651..1070821) Streptococcus pneumoniae AP200 9727138 YP_003876715.1 CDS SPAP_1124 NC_014494.1 1071093 1071851 R Operon 506 Gene 1 COG1101 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase complement(1071093..1071851) Streptococcus pneumoniae AP200 9727139 YP_003876716.1 CDS SPAP_1125 NC_014494.1 1071848 1072714 R Operon 506 Gene 2 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease complement(1071848..1072714) Streptococcus pneumoniae AP200 9727140 YP_003876717.1 CDS SPAP_1126 NC_014494.1 1072783 1073787 R Operon 506 Gene 3 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic complement(1072783..1073787) Streptococcus pneumoniae AP200 9727141 YP_003876718.1 CDS SPAP_1127 NC_014494.1 1074200 1076896 R Operon 507 Gene 1 COG2352 Phosphoenolpyruvate carboxylase; phosphoenolpyruvate carboxylase complement(1074200..1076896) Streptococcus pneumoniae AP200 9727142 YP_003876719.1 CDS SPAP_1128 NC_014494.1 1076916 1078145 R Operon 507 Gene 2 COG0772 Bacterial cell division membrane protein; cell division membrane protein complement(1076916..1078145) Streptococcus pneumoniae AP200 9727143 YP_003876720.1 CDS SPAP_1129 NC_014494.1 1078409 1078603 R transposase-like protein, IS1381 ISSpn7 complement(1078409..1078603) Streptococcus pneumoniae AP200 9727144 YP_003876721.1 CDS SPAP_1130 NC_014494.1 1078702 1078965 D Operon 509 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1078702..1078965 Streptococcus pneumoniae AP200 9727145 YP_003876722.1 CDS SPAP_1131 NC_014494.1 1079052 1079273 R Operon 510 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1079052..1079273) Streptococcus pneumoniae AP200 9727146 YP_003876723.1 CDS SPAP_1132 NC_014494.1 1079953 1080705 R Operon 511 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(1079953..1080705) Streptococcus pneumoniae AP200 9727147 YP_003876724.1 CDS SPAP_1133 NC_014494.1 1080757 1081164 R Operon 511 Gene 2 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(1080757..1081164) Streptococcus pneumoniae AP200 9727148 YP_003876725.1 CDS SPAP_1134 NC_014494.1 1081166 1082110 R Operon 511 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1081166..1082110) Streptococcus pneumoniae AP200 9727149 YP_003876726.1 CDS SPAP_1135 NC_014494.1 1082251 1082616 R Operon 512 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 complement(1082251..1082616) Streptococcus pneumoniae AP200 9727150 YP_003876727.1 CDS SPAP_1136 NC_014494.1 1082628 1083053 R transposase-like protein, IS1515 complement(1082628..1083053) Streptococcus pneumoniae AP200 9727151 YP_003876728.1 CDS SPAP_1137 NC_014494.1 1083079 1083282 R Operon 512 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1083079..1083282) Streptococcus pneumoniae AP200 9727152 YP_003876729.1 CDS SPAP_1138 NC_014494.1 1083306 1084334 R Operon 512 Gene 4 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(1083306..1084334) Streptococcus pneumoniae AP200 9727153 YP_003876730.1 CDS SPAP_1139 NC_014494.1 1084336 1085007 R Operon 512 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(1084336..1085007) Streptococcus pneumoniae AP200 9727154 YP_003876731.1 CDS SPAP_1140 NC_014494.1 1085010 1086104 R Operon 512 Gene 6 Putative gene predicted by FgenesB; hypothetical protein complement(1085010..1086104) Streptococcus pneumoniae AP200 9727155 YP_003876732.1 CDS SPAP_1141 NC_014494.1 1086108 1086284 R Operon 512 Gene 7 Putative gene predicted by FgenesB; hypothetical protein complement(1086108..1086284) Streptococcus pneumoniae AP200 9727156 YP_003876733.1 CDS SPAP_1142 NC_014494.1 1086636 1087358 R Operon 513 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1086636..1087358) Streptococcus pneumoniae AP200 9727157 YP_003876734.1 CDS SPAP_1143 NC_014494.1 1087345 1087764 R Operon 513 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1087345..1087764) Streptococcus pneumoniae AP200 9727158 YP_003876735.1 CDS SPAP_1144 NC_014494.1 1088471 1089322 D Operon 514 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator 1088471..1089322 Streptococcus pneumoniae AP200 9727159 YP_003876736.1 CDS SPAP_1145 NC_014494.1 1089363 1089950 R Operon 515 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1089363..1089950) Streptococcus pneumoniae AP200 9727160 YP_003876737.1 CDS SPAP_1146 NC_014494.1 1090089 1090289 R Operon 516 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1090089..1090289) Streptococcus pneumoniae AP200 9727161 YP_003876738.1 CDS SPAP_1147 NC_014494.1 1090325 1090519 R Operon 516 Gene 2 COG3843 Type IV secretory pathway, VirD2 components (relaxase); type IV secretory pathway, VirD2 components (relaxase) complement(1090325..1090519) Streptococcus pneumoniae AP200 9727162 YP_003876739.1 CDS SPAP_1148 NC_014494.1 1090648 1091775 R Operon 517 Gene 1 COG0366 Glycosidases; glycosidase complement(1090648..1091775) Streptococcus pneumoniae AP200 9727163 YP_003876740.1 CDS SPAP_1149 NC_014494.1 1091938 1092822 R Operon 518 Gene 1 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase; sphingosine kinase complement(1091938..1092822) Streptococcus pneumoniae AP200 9727164 YP_003876741.1 CDS SPAP_1150 NC_014494.1 1092934 1093788 R Operon 519 Gene 1 COG1397 ADP-ribosylglycohydrolase; ADP-ribosylglycohydrolase complement(1092934..1093788) Streptococcus pneumoniae AP200 9727165 YP_003876742.1 CDS SPAP_1151 NC_014494.1 1093846 1094604 R Operon 519 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1093846..1094604) Streptococcus pneumoniae AP200 9727166 YP_003876743.1 CDS SPAP_1152 NC_014494.1 1094666 1094860 R Operon 519 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1094666..1094860) Streptococcus pneumoniae AP200 9727167 YP_003876744.1 CDS SPAP_1153 NC_014494.1 1095042 1095203 D Operon 520 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1095042..1095203 Streptococcus pneumoniae AP200 9727168 YP_003876745.1 CDS SPAP_1154 NC_014494.1 1095175 1095741 R Operon 521 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1095175..1095741) Streptococcus pneumoniae AP200 9727169 YP_003876746.1 CDS SPAP_1155 NC_014494.1 1096009 1097688 R Operon 522 Gene 1 COG1961 Site-specific recombinases, DNA invertase Pin homologs; site-specific recombinase complement(1096009..1097688) Streptococcus pneumoniae AP200 9727170 YP_003876747.1 CDS SPAP_1156 NC_014494.1 1097779 1097940 R Operon 522 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1097779..1097940) Streptococcus pneumoniae AP200 9727171 YP_003876748.1 CDS SPAP_1157 NC_014494.1 1098624 1099352 R Operon 523 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1098624..1099352) Streptococcus pneumoniae AP200 9727172 YP_003876749.1 CDS SPAP_1158 NC_014494.1 1099479 1100006 R Operon 523 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1099479..1100006) Streptococcus pneumoniae AP200 9727173 YP_003876750.1 CDS SPAP_1159 NC_014494.1 1100192 1100365 R Operon 524 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1100192..1100365) Streptococcus pneumoniae AP200 9727174 YP_003876751.1 CDS SPAP_1160 NC_014494.1 1100439 1102079 R Operon 524 Gene 2 COG0507 ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member; ATP-dependent exoDNAse (exonuclease V) subunit alpha complement(1100439..1102079) Streptococcus pneumoniae AP200 9727175 YP_003876752.1 CDS SPAP_1161 NC_014494.1 1102389 1102703 R Operon 525 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1102389..1102703) Streptococcus pneumoniae AP200 9727176 YP_003876753.1 CDS SPAP_1162 NC_014494.1 1102762 1103007 R Operon 525 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1102762..1103007) Streptococcus pneumoniae AP200 9727177 YP_003876754.1 CDS SPAP_1163 NC_014494.1 1102953 1103066 D Operon 526 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1102953..1103066 Streptococcus pneumoniae AP200 9727178 YP_003876755.1 CDS SPAP_1164 NC_014494.1 1103575 1104369 R Operon 527 Gene 1 COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components; cobalamin/Fe3+-siderophores ABC transporter ATPase complement(1103575..1104369) Streptococcus pneumoniae AP200 9727179 YP_003876756.1 CDS SPAP_1165 NC_014494.1 1104369 1105376 R Operon 527 Gene 2 COG0609 ABC-type Fe3+-siderophore transport system, permease component; Fe3+-siderophore ABC transporter permease complement(1104369..1105376) Streptococcus pneumoniae AP200 9727180 YP_003876757.1 CDS SPAP_1166 NC_014494.1 1105376 1105720 R Operon 527 Gene 3 COG0609 ABC-type Fe3+-siderophore transport system, permease component; Fe3+-siderophore ABC transporter permease complement(1105376..1105720) Streptococcus pneumoniae AP200 9727181 YP_003876758.1 CDS SPAP_1167 NC_014494.1 1106373 1107398 R Operon 527 Gene 4 COG0614 ABC-type Fe3+-hydroxamate transport system, periplasmic component; Fe3+-hydroxamate ABC transporter periplasmic protein complement(1106373..1107398) Streptococcus pneumoniae AP200 9727182 YP_003876759.1 CDS SPAP_1168 NC_014494.1 1107519 1107788 R Operon 528 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1107519..1107788) Streptococcus pneumoniae AP200 9727183 YP_003876760.1 CDS SPAP_1169 NC_014494.1 1107792 1108010 R Operon 528 Gene 2 COG3655 Predicted transcriptional regulator; putative transcriptional regulator complement(1107792..1108010) Streptococcus pneumoniae AP200 9727184 YP_003876761.1 CDS SPAP_1170 NC_014494.1 1108748 1110379 R Operon 529 Gene 1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; SAM-dependent methyltransferase complement(1108748..1110379) Streptococcus pneumoniae AP200 9727185 YP_003876762.1 CDS SPAP_1171 NC_014494.1 1110453 1111427 R Operon 530 Gene 1 COG4086 Predicted secreted protein; hypothetical protein complement(1110453..1111427) Streptococcus pneumoniae AP200 9727186 YP_003876763.1 CDS SPAP_1172 NC_014494.1 1111501 1112115 R Operon 530 Gene 2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains); soluble lytic murein transglycosylase-like regulatory protein complement(1111501..1112115) Streptococcus pneumoniae AP200 9727187 YP_003876764.1 CDS SPAP_1173 NC_014494.1 1112115 1113089 R Operon 530 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1112115..1113089) Streptococcus pneumoniae AP200 9727188 YP_003876765.1 CDS SPAP_1174 NC_014494.1 1113097 1114353 R Operon 530 Gene 4 COG0112 Glycine/serine hydroxymethyltransferase; glycine/serine hydroxymethyltransferase complement(1113097..1114353) Streptococcus pneumoniae AP200 9727189 YP_003876766.1 CDS SPAP_1175 NC_014494.1 1114415 1114846 R Operon 530 Gene 5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1114415..1114846) Streptococcus pneumoniae AP200 9727190 YP_003876767.1 CDS SPAP_1176 NC_014494.1 1114848 1115450 R Operon 530 Gene 6 COG0009 Putative translation factor (SUA5); putative translation factor complement(1114848..1115450) Streptococcus pneumoniae AP200 9727191 YP_003876768.1 CDS SPAP_1177 NC_014494.1 1115434 1116273 R Operon 530 Gene 7 COG2890 Methylase of polypeptide chain release factors; methylase of polypeptide chain release factors complement(1115434..1116273) Streptococcus pneumoniae AP200 9727192 YP_003876769.1 CDS SPAP_1178 NC_014494.1 1116273 1117352 R Operon 530 Gene 8 COG0216 Protein chain release factor A; protein chain release factor A complement(1116273..1117352) Streptococcus pneumoniae AP200 9727193 YP_003876770.1 CDS SPAP_1179 NC_014494.1 1117362 1117841 R Operon 530 Gene 9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1117362..1117841) Streptococcus pneumoniae AP200 9727194 YP_003876771.1 CDS SPAP_1180 NC_014494.1 1117831 1118430 R Operon 530 Gene 10 COG1435 Thymidine kinase; thymidine kinase complement(1117831..1118430) Streptococcus pneumoniae AP200 9727195 YP_003876772.1 CDS SPAP_1181 NC_014494.1 1118553 1118735 D Operon 531 Gene 1 COG1942 Uncharacterized protein, 4-oxalocrotonate tautomerase homolog; hypothetical protein 1118553..1118735 Streptococcus pneumoniae AP200 9727196 YP_003876773.1 CDS SPAP_1182 NC_014494.1 1118872 1120245 D Operon 532 Gene 1 COG0486 Predicted GTPase; putative GTPase 1118872..1120245 Streptococcus pneumoniae AP200 9727197 YP_003876774.1 CDS SPAP_1183 NC_014494.1 1120292 1121227 R Operon 533 Gene 1 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase complement(1120292..1121227) Streptococcus pneumoniae AP200 9727198 YP_003876775.1 CDS SPAP_1184 NC_014494.1 1121283 1122359 R Operon 533 Gene 2 COG0136 Aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase complement(1121283..1122359) Streptococcus pneumoniae AP200 9727199 YP_003876776.1 CDS SPAP_1186 NC_014494.1 1123117 1123626 R Operon 534 Gene 1 COG4708 Predicted membrane protein; hypothetical protein complement(1123117..1123626) Streptococcus pneumoniae AP200 9727201 YP_003876777.1 CDS SPAP_1187 NC_014494.1 1123749 1124180 D Operon 535 Gene 1 COG2246 Predicted membrane protein; hypothetical protein 1123749..1124180 Streptococcus pneumoniae AP200 9727202 YP_003876778.1 CDS SPAP_1188 NC_014494.1 1124262 1124639 D Operon 535 Gene 2 COG1970 Large-conductance mechanosensitive channel; large-conductance mechanosensitive channel 1124262..1124639 Streptococcus pneumoniae AP200 9727203 YP_003876779.1 CDS SPAP_1189 NC_014494.1 1124681 1125775 R Operon 536 Gene 1 COG0276 Protoheme ferro-lyase (ferrochelatase); protoheme ferro-lyase complement(1124681..1125775) Streptococcus pneumoniae AP200 9727204 YP_003876780.1 CDS SPAP_1190 NC_014494.1 1125853 1126032 R Operon 536 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1125853..1126032) Streptococcus pneumoniae AP200 9727205 YP_003876781.1 CDS srtG2 NC_014494.1 1126077 1126685 R Operon 536 Gene 3 COG4509 Uncharacterized protein conserved in bacteria; sortase SrtG2 complement(1126077..1126685) Streptococcus pneumoniae AP200 9727206 YP_003876782.1 CDS srtG1 NC_014494.1 1126763 1127761 R Operon 537 Gene 1 COG4509 Uncharacterized protein conserved in bacteria; sortase SrtG1 complement(1126763..1127761) Streptococcus pneumoniae AP200 9727207 YP_003876783.1 CDS pitB NC_014494.1 1127779 1128975 R LPXTG containing cell wall anchored protein; pilus backbone; PitB complement(1127779..1128975) Streptococcus pneumoniae AP200 9727208 YP_003876784.1 CDS sipA NC_014494.1 1129020 1129571 R Operon 537 Gene 3 COG0681 Signal peptidase I; signal peptidase-like protein sipA complement(1129020..1129571) Streptococcus pneumoniae AP200 9727209 YP_003876785.1 CDS SPAP_1195 NC_014494.1 1129571 1131397 R Operon 537 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1129571..1131397) Streptococcus pneumoniae AP200 9727210 YP_003876786.1 CDS SPAP_1196 NC_014494.1 1131653 1132156 R Operon 538 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1131653..1132156) Streptococcus pneumoniae AP200 9727211 YP_003876787.1 CDS SPAP_1197 NC_014494.1 1132515 1133738 D Operon 539 Gene 1 COG2195 Di- and tripeptidases; di- and tripeptidase 1132515..1133738 Streptococcus pneumoniae AP200 9727212 YP_003876788.1 CDS SPAP_1198 NC_014494.1 1133774 1134403 R Operon 540 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1133774..1134403) Streptococcus pneumoniae AP200 9727213 YP_003876789.1 CDS SPAP_1199 NC_014494.1 1134698 1134937 R Operon 541 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1134698..1134937) Streptococcus pneumoniae AP200 9727214 YP_003876790.1 CDS SPAP_1200 NC_014494.1 1134927 1135235 R Operon 541 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1134927..1135235) Streptococcus pneumoniae AP200 9727215 YP_003876791.1 CDS SPAP_1201 NC_014494.1 1136099 1139218 R Operon 542 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1136099..1139218) Streptococcus pneumoniae AP200 9727216 YP_003876792.1 CDS SPAP_1202 NC_014494.1 1139428 1140462 R Operon 543 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1139428..1140462) Streptococcus pneumoniae AP200 9727217 YP_003876793.1 CDS SPAP_1203 NC_014494.1 1140521 1141255 R Operon 543 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1140521..1141255) Streptococcus pneumoniae AP200 9727218 YP_003876794.1 CDS SPAP_1204 NC_014494.1 1141277 1141945 R Operon 543 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1141277..1141945) Streptococcus pneumoniae AP200 9727219 YP_003876795.1 CDS SPAP_1205 NC_014494.1 1142103 1144553 R Operon 544 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1142103..1144553) Streptococcus pneumoniae AP200 9727220 YP_003876796.1 CDS SPAP_1206 NC_014494.1 1144806 1146530 R Operon 545 Gene 1 COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); PTS system phosphoenolpyruvate-protein kinase complement(1144806..1146530) Streptococcus pneumoniae AP200 9727221 YP_003876797.1 CDS SPAP_1207 NC_014494.1 1146545 1146808 R Operon 545 Gene 2 COG1925 Phosphotransferase system, HPr-related proteins; PTS system HPr-related protein complement(1146545..1146808) Streptococcus pneumoniae AP200 9727222 YP_003876798.1 CDS SPAP_1208 NC_014494.1 1147159 1147377 D Operon 546 Gene 1 COG0695 Glutaredoxin and related proteins; glutaredoxin-like protein 1147159..1147377 Streptococcus pneumoniae AP200 9727223 YP_003876799.1 CDS SPAP_1209 NC_014494.1 1147458 1149617 D Operon 546 Gene 2 COG0209 Ribonucleotide reductase, alpha subunit; ribonucleotide reductase subunit alpha 1147458..1149617 Streptococcus pneumoniae AP200 9727224 YP_003876800.1 CDS SPAP_1210 NC_014494.1 1149805 1150767 D Operon 546 Gene 3 COG0208 Ribonucleotide reductase, beta subunit; ribonucleotide reductase subunit beta 1149805..1150767 Streptococcus pneumoniae AP200 9727225 YP_003876801.1 CDS SPAP_1211 NC_014494.1 1150949 1151710 D Operon 547 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 1150949..1151710 Streptococcus pneumoniae AP200 9727226 YP_003876802.1 CDS SPAP_1212 NC_014494.1 1151995 1152246 R Operon 548 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1151995..1152246) Streptococcus pneumoniae AP200 9727227 YP_003876803.1 CDS SPAP_1213 NC_014494.1 1152289 1153695 R Operon 548 Gene 2 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase complement(1152289..1153695) Streptococcus pneumoniae AP200 9727228 YP_003876804.1 CDS SPAP_1214 NC_014494.1 1153910 1155604 R Operon 548 Gene 3 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC complement(1153910..1155604) Streptococcus pneumoniae AP200 9727229 YP_003876805.1 CDS SPAP_1215 NC_014494.1 1155606 1155923 R Operon 548 Gene 4 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA complement(1155606..1155923) Streptococcus pneumoniae AP200 9727230 YP_003876806.1 CDS SPAP_1216 NC_014494.1 1155959 1156795 R Operon 548 Gene 5 COG3711 Transcriptional antiterminator; transcriptional antiterminator complement(1155959..1156795) Streptococcus pneumoniae AP200 9727231 YP_003876807.1 CDS SPAP_1217 NC_014494.1 1157029 1158009 R Operon 549 Gene 1 COG3684 Tagatose-1,6-bisphosphate aldolase; tagatose-1,6-bisphosphate aldolase complement(1157029..1158009) Streptococcus pneumoniae AP200 9727232 YP_003876808.1 CDS SPAP_1218 NC_014494.1 1158011 1158940 R Operon 549 Gene 2 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); fructose-1-phosphate kinase-like fructose-6-phosphate kinase PfkB complement(1158011..1158940) Streptococcus pneumoniae AP200 9727233 YP_003876809.1 CDS SPAP_1219 NC_014494.1 1158951 1159466 R Operon 549 Gene 3 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB complement(1158951..1159466) Streptococcus pneumoniae AP200 9727234 YP_003876810.1 CDS SPAP_1220 NC_014494.1 1159497 1159922 R Operon 549 Gene 4 COG0698 Ribose 5-phosphate isomerase RpiB; ribose 5-phosphate isomerase RpiB complement(1159497..1159922) Streptococcus pneumoniae AP200 9727235 YP_003876811.1 CDS SPAP_1221 NC_014494.1 1160079 1160555 R Operon 550 Gene 1 COG2017 Galactose mutarotase and related enzymes; galactose mutarotase-like enzyme complement(1160079..1160555) Streptococcus pneumoniae AP200 9727236 YP_003876812.1 CDS SPAP_1222 NC_014494.1 1160592 1161056 R transposase-like protein, IS1381 ISSpn7 complement(1160592..1161056) Streptococcus pneumoniae AP200 9727237 YP_003876813.1 CDS SPAP_1223 NC_014494.1 1161215 1161397 R transposase-like protein, IS1381 ISSpn7 complement(1161215..1161397) Streptococcus pneumoniae AP200 9727238 YP_003876814.1 CDS SPAP_1224 NC_014494.1 1161752 1162228 R Operon 552 Gene 1 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein complement(1161752..1162228) Streptococcus pneumoniae AP200 9727239 YP_003876815.1 CDS SPAP_1225 NC_014494.1 1162408 1162695 D Operon 553 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1162408..1162695 Streptococcus pneumoniae AP200 9727240 YP_003876816.1 CDS SPAP_1226 NC_014494.1 1162776 1164599 R Operon 554 Gene 1 COG0481 Membrane GTPase LepA; membrane GTPase LepA complement(1162776..1164599) Streptococcus pneumoniae AP200 9727241 YP_003876817.1 CDS SPAP_1227 NC_014494.1 1164678 1165406 R Operon 554 Gene 2 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase complement(1164678..1165406) Streptococcus pneumoniae AP200 9727242 YP_003876818.1 CDS SPAP_1228 NC_014494.1 1165408 1167075 R Operon 554 Gene 3 COG0497 ATPase involved in DNA repair; DNA repair ATPase complement(1165408..1167075) Streptococcus pneumoniae AP200 9727243 YP_003876819.1 CDS SPAP_1229 NC_014494.1 1167082 1167513 R Operon 554 Gene 4 COG1438 Arginine repressor; arginine repressor complement(1167082..1167513) Streptococcus pneumoniae AP200 9727244 YP_003876820.1 CDS SPAP_1230 NC_014494.1 1167506 1168321 R Operon 554 Gene 5 COG1189 Predicted rRNA methylase; putative rRNA methylase complement(1167506..1168321) Streptococcus pneumoniae AP200 9727245 YP_003876821.1 CDS SPAP_1231 NC_014494.1 1168314 1169189 R Operon 554 Gene 6 COG0142 Geranylgeranyl pyrophosphate synthase; geranylgeranyl pyrophosphate synthase complement(1168314..1169189) Streptococcus pneumoniae AP200 9727246 YP_003876822.1 CDS SPAP_1232 NC_014494.1 1169186 1169398 R Operon 554 Gene 7 COG1722 Exonuclease VII small subunit; exonuclease VII small subunit complement(1169186..1169398) Streptococcus pneumoniae AP200 9727247 YP_003876823.1 CDS SPAP_1233 NC_014494.1 1169376 1170716 R Operon 554 Gene 8 COG1570 Exonuclease VII, large subunit; exonuclease VII large subunit complement(1169376..1170716) Streptococcus pneumoniae AP200 9727248 YP_003876824.1 CDS SPAP_1234 NC_014494.1 1170844 1171482 R Operon 555 Gene 1 COG0572 Uridine kinase; Uridine kinase complement(1170844..1171482) Streptococcus pneumoniae AP200 9727249 YP_003876825.1 CDS SPAP_1235 NC_014494.1 1171590 1171889 R Operon 556 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1171590..1171889) Streptococcus pneumoniae AP200 9727250 YP_003876826.1 CDS SPAP_1236 NC_014494.1 1171889 1171984 R Operon 556 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1171889..1171984) Streptococcus pneumoniae AP200 9727251 YP_003876827.1 CDS SPAP_1237 NC_014494.1 1172133 1173011 R Operon 557 Gene 1 COG0130 Pseudouridine synthase; pseudouridine synthase complement(1172133..1173011) Streptococcus pneumoniae AP200 9727252 YP_003876828.1 CDS SPAP_1238 NC_014494.1 1173112 1176042 R Operon 558 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1173112..1176042) Streptococcus pneumoniae AP200 9727253 YP_003876829.1 CDS SPAP_1239 NC_014494.1 1176030 1176227 R Operon 558 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1176030..1176227) Streptococcus pneumoniae AP200 9727254 YP_003876830.1 CDS SPAP_1240 NC_014494.1 1176239 1177513 R Operon 558 Gene 3 COG4487 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1176239..1177513) Streptococcus pneumoniae AP200 9727255 YP_003876831.1 CDS SPAP_1241 NC_014494.1 1177609 1178724 R Operon 559 Gene 1 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase complement(1177609..1178724) Streptococcus pneumoniae AP200 9727256 YP_003876832.1 CDS SPAP_1242 NC_014494.1 1178746 1178868 R Operon 559 Gene 2 COG2873 O-acetylhomoserine sulfhydrylase; O-acetylhomoserine sulfhydrylase complement(1178746..1178868) Streptococcus pneumoniae AP200 9727257 YP_003876833.1 CDS SPAP_1243 NC_014494.1 1179016 1179813 R Operon 560 Gene 1 COG2116 Formate/nitrite family of transporters; formate/nitrite family transporter complement(1179016..1179813) Streptococcus pneumoniae AP200 9727258 YP_003876834.1 CDS SPAP_1244 NC_014494.1 1180058 1180801 R Operon 561 Gene 1 COG3764 Sortase (surface protein transpeptidase); sortase complement(1180058..1180801) Streptococcus pneumoniae AP200 9727259 YP_003876835.1 CDS SPAP_1245 NC_014494.1 1180801 1183269 R Operon 561 Gene 2 COG0188 Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit; type IIA topoisomerase subunit A complement(1180801..1183269) Streptococcus pneumoniae AP200 9727260 YP_003876836.1 CDS SPAP_1246 NC_014494.1 1183463 1184449 D Operon 562 Gene 1 COG0039 Malate/lactate dehydrogenases; malate/lactate dehydrogenase 1183463..1184449 Streptococcus pneumoniae AP200 9727261 YP_003876837.1 CDS SPAP_1247 NC_014494.1 1184798 1185493 R Operon 563 Gene 1 COG1226 Kef-type K+ transport systems, predicted NAD-binding component; K+ transport systems NAD-binding component complement(1184798..1185493) Streptococcus pneumoniae AP200 9727262 YP_003876838.1 CDS SPAP_1248 NC_014494.1 1185540 1185803 R Operon 563 Gene 2 COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; cytotoxic translational repressor of toxin-antitoxin stability system complement(1185540..1185803) Streptococcus pneumoniae AP200 9727263 YP_003876839.1 CDS SPAP_1249 NC_014494.1 1185796 1186038 R Operon 563 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1185796..1186038) Streptococcus pneumoniae AP200 9727264 YP_003876840.1 CDS SPAP_1250 NC_014494.1 1186129 1186938 R Operon 564 Gene 1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I; metal-dependent hydrolases of the beta-lactamase superfamily I complement(1186129..1186938) Streptococcus pneumoniae AP200 9727265 YP_003876841.1 CDS SPAP_1251 NC_014494.1 1186940 1188289 R Operon 564 Gene 2 COG5002 Signal transduction histidine kinase; signal transduction histidine kinase complement(1186940..1188289) Streptococcus pneumoniae AP200 9727266 YP_003876842.1 CDS SPAP_1252 NC_014494.1 1188282 1188986 R Operon 564 Gene 3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator complement(1188282..1188986) Streptococcus pneumoniae AP200 9727267 YP_003876843.1 CDS SPAP_1253 NC_014494.1 1189041 1190216 R Operon 564 Gene 4 COG1194 A/G-specific DNA glycosylase; A/G-specific DNA glycosylase complement(1189041..1190216) Streptococcus pneumoniae AP200 9727268 YP_003876844.1 CDS SPAP_1254 NC_014494.1 1190544 1192214 R Operon 565 Gene 1 COG2759 Formyltetrahydrofolate synthetase; formyltetrahydrofolate synthetase complement(1190544..1192214) Streptococcus pneumoniae AP200 9727269 YP_003876845.1 CDS SPAP_1255 NC_014494.1 1192444 1193133 D Operon 566 Gene 1 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; phosphopantothenoylcysteine synthetase/decarboxylase 1192444..1193133 Streptococcus pneumoniae AP200 9727270 YP_003876846.1 CDS SPAP_1256 NC_014494.1 1193145 1193696 D Operon 566 Gene 2 COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; phosphopantothenoylcysteine synthetase/decarboxylase 1193145..1193696 Streptococcus pneumoniae AP200 9727271 YP_003876847.1 CDS SPAP_1257 NC_014494.1 1193680 1194243 D Operon 566 Gene 3 COG4684 Predicted membrane protein; hypothetical protein 1193680..1194243 Streptococcus pneumoniae AP200 9727272 YP_003876848.1 CDS SPAP_1258 NC_014494.1 1194552 1195052 D Operon 567 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1194552..1195052 Streptococcus pneumoniae AP200 9727273 YP_003876849.1 CDS SPAP_1259 NC_014494.1 1195064 1195579 D Operon 567 Gene 2 COG1827 Predicted small molecule binding protein (contains 3H domain); putative small molecule binding protein 1195064..1195579 Streptococcus pneumoniae AP200 9727274 YP_003876850.1 CDS SPAP_1260 NC_014494.1 1195576 1196043 R Operon 568 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes complement(1195576..1196043) Streptococcus pneumoniae AP200 9727275 YP_003876851.1 CDS SPAP_1261 NC_014494.1 1196116 1196604 R Operon 568 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1196116..1196604) Streptococcus pneumoniae AP200 9727276 YP_003876852.1 CDS SPAP_1262 NC_014494.1 1196570 1197133 R Operon 568 Gene 3 protein supported gi|116629704|ref|YP_814876.1| acetyltransferase; hypothetical protein complement(1196570..1197133) Streptococcus pneumoniae AP200 9727277 YP_003876853.1 CDS SPAP_1263 NC_014494.1 1197143 1199131 R Operon 568 Gene 4 COG0556 Helicase subunit of the DNA excision repair complex; DNA excision repair complex helicase complement(1197143..1199131) Streptococcus pneumoniae AP200 9727278 YP_003876854.1 CDS SPAP_1264 NC_014494.1 1199208 1200161 R Operon 568 Gene 5 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease complement(1199208..1200161) Streptococcus pneumoniae AP200 9727279 YP_003876855.1 CDS SPAP_1265 NC_014494.1 1200331 1202496 D Operon 569 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein 1200331..1202496 Streptococcus pneumoniae AP200 9727280 YP_003876856.1 CDS SPAP_1266 NC_014494.1 1202496 1203236 D Operon 569 Gene 2 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein 1202496..1203236 Streptococcus pneumoniae AP200 9727281 YP_003876857.1 CDS SPAP_1267 NC_014494.1 1203385 1204872 D Operon 570 Gene 1 COG0364 Glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 1203385..1204872 Streptococcus pneumoniae AP200 9727282 YP_003876858.1 CDS SPAP_1268 NC_014494.1 1204918 1206195 R Operon 571 Gene 1 protein supported gi|163762490|ref|ZP_02169555.1| ribosomal protein L28; hypothetical protein complement(1204918..1206195) Streptococcus pneumoniae AP200 9727283 YP_003876859.1 CDS SPAP_1269 NC_014494.1 1206199 1207017 R Operon 571 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(1206199..1207017) Streptococcus pneumoniae AP200 9727284 YP_003876860.1 CDS SPAP_1270 NC_014494.1 1207017 1207811 R Operon 571 Gene 3 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(1207017..1207811) Streptococcus pneumoniae AP200 9727285 YP_003876861.1 CDS SPAP_1271 NC_014494.1 1207808 1211347 R Operon 571 Gene 4 COG1196 Chromosome segregation ATPases; chromosome segregation ATPase complement(1207808..1211347) Streptococcus pneumoniae AP200 9727286 YP_003876862.1 CDS SPAP_1272 NC_014494.1 1211338 1212036 R Operon 571 Gene 5 COG0571 dsRNA-specific ribonuclease; dsRNA-specific ribonuclease complement(1211338..1212036) Streptococcus pneumoniae AP200 9727287 YP_003876863.1 CDS SPAP_1274 NC_014494.1 1212354 1213340 R Operon 572 Gene 1 COG0516 IMP dehydrogenase/GMP reductase; IMP dehydrogenase/GMP reductase complement(1212354..1213340) Streptococcus pneumoniae AP200 9727289 YP_003876864.1 CDS SPAP_1275 NC_014494.1 1213515 1214834 R Operon 573 Gene 1 COG4268 McrBC 5-methylcytosine restriction system component; McrBC 5-methylcytosine restriction system component complement(1213515..1214834) Streptococcus pneumoniae AP200 9727290 YP_003876865.1 CDS SPAP_1276 NC_014494.1 1214818 1216749 R Operon 573 Gene 2 COG1401 GTPase subunit of restriction endonuclease; restriction endonuclease GTPase subunit complement(1214818..1216749) Streptococcus pneumoniae AP200 9727291 YP_003876866.1 CDS SPAP_1277 NC_014494.1 1216913 1217074 R Operon 574 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1216913..1217074) Streptococcus pneumoniae AP200 9727292 YP_003876867.1 CDS SPAP_1278 NC_014494.1 1217335 1217478 R Operon 575 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1217335..1217478) Streptococcus pneumoniae AP200 9727293 YP_003876868.1 CDS SPAP_1279 NC_014494.1 1217697 1218056 R Operon 576 Gene 1 COG0066 3-isopropylmalate dehydratase small subunit; 3-isopropylmalate dehydratase small subunit complement(1217697..1218056) Streptococcus pneumoniae AP200 9727294 YP_003876869.1 CDS SPAP_1280 NC_014494.1 1218060 1218329 R Operon 576 Gene 2 COG3326 Predicted membrane protein; hypothetical protein complement(1218060..1218329) Streptococcus pneumoniae AP200 9727295 YP_003876870.1 CDS SPAP_1281 NC_014494.1 1218326 1219363 R Operon 576 Gene 3 COG0473 Isocitrate/isopropylmalate dehydrogenase; isocitrate/isopropylmalate dehydrogenase complement(1218326..1219363) Streptococcus pneumoniae AP200 9727296 YP_003876871.1 CDS SPAP_1282 NC_014494.1 1219375 1219794 R Operon 576 Gene 4 COG0119 Isopropylmalate/homocitrate/citramalate synthases; isopropylmalate/homocitrate/citramalate synthase complement(1219375..1219794) Streptococcus pneumoniae AP200 9727297 YP_003876872.1 CDS SPAP_1283 NC_014494.1 1219837 1220469 R Operon 576 Gene 5 COG0119 Isopropylmalate/homocitrate/citramalate synthases; isopropylmalate/homocitrate/citramalate synthase complement(1219837..1220469) Streptococcus pneumoniae AP200 9727298 YP_003876873.1 CDS SPAP_1284 NC_014494.1 1220488 1221144 R Operon 576 Gene 6 COG2315 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1220488..1221144) Streptococcus pneumoniae AP200 9727299 YP_003876874.1 CDS SPAP_1285 NC_014494.1 1221188 1221820 R Operon 576 Gene 7 COG3142 Uncharacterized protein involved in copper resistance; hypothetical protein complement(1221188..1221820) Streptococcus pneumoniae AP200 9727300 YP_003876875.1 CDS SPAP_1286 NC_014494.1 1221913 1222203 R Operon 577 Gene 1 COG2832 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1221913..1222203) Streptococcus pneumoniae AP200 9727301 YP_003876876.1 CDS SPAP_1287 NC_014494.1 1222379 1224466 R Operon 578 Gene 1 COG0550 Topoisomerase IA; topoisomerase IA complement(1222379..1224466) Streptococcus pneumoniae AP200 9727302 YP_003876877.1 CDS SPAP_1288 NC_014494.1 1224633 1225676 R Operon 579 Gene 1 COG1808 Predicted membrane protein; hypothetical protein complement(1224633..1225676) Streptococcus pneumoniae AP200 9727303 YP_003876878.1 CDS SPAP_1289 NC_014494.1 1226280 1226603 D transposase-like protein, IS1239 1226280..1226603 Streptococcus pneumoniae AP200 9727304 YP_003876879.1 CDS SPAP_1290 NC_014494.1 1226603 1227214 D transposase-like protein, IS1239 1226603..1227214 Streptococcus pneumoniae AP200 9727305 YP_003876880.1 CDS SPAP_1291 NC_014494.1 1227804 1228652 R Operon 581 Gene 1 COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; putative DNA uptake Rossmann fold nucleotide-binding protein complement(1227804..1228652) Streptococcus pneumoniae AP200 9727306 YP_003876881.1 CDS SPAP_1292 NC_014494.1 1228749 1229438 R Operon 581 Gene 2 COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes; CTP:phosphocholine cytidylyltransferase complement(1228749..1229438) Streptococcus pneumoniae AP200 9727307 YP_003876882.1 CDS SPAP_1293 NC_014494.1 1229450 1230340 R Operon 581 Gene 3 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease complement(1229450..1230340) Streptococcus pneumoniae AP200 9727308 YP_003876883.1 CDS SPAP_1294 NC_014494.1 1230318 1231187 R Operon 581 Gene 4 COG0510 Predicted choline kinase involved in LPS biosynthesis; putative choline kinase complement(1230318..1231187) Streptococcus pneumoniae AP200 9727309 YP_003876884.1 CDS SPAP_1295 NC_014494.1 1231204 1232226 R Operon 581 Gene 5 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase complement(1231204..1232226) Streptococcus pneumoniae AP200 9727310 YP_003876885.1 CDS SPAP_1296 NC_014494.1 1232231 1232938 R Operon 581 Gene 6 COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; 4-diphosphocytidyl-2-methyl-D-erithritol synthase complement(1232231..1232938) Streptococcus pneumoniae AP200 9727311 YP_003876886.1 CDS SPAP_1297 NC_014494.1 1233274 1234761 D Operon 582 Gene 1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen and teichoic acid exporter membrane protein 1233274..1234761 Streptococcus pneumoniae AP200 9727312 YP_003876887.1 CDS SPAP_1298 NC_014494.1 1234771 1235574 D Operon 582 Gene 2 COG3475 LPS biosynthesis protein; LPS biosynthesis protein 1234771..1235574 Streptococcus pneumoniae AP200 9727313 YP_003876888.1 CDS SPAP_1299 NC_014494.1 1235576 1236385 D Operon 582 Gene 3 COG3475 LPS biosynthesis protein; LPS biosynthesis protein 1235576..1236385 Streptococcus pneumoniae AP200 9727314 YP_003876889.1 CDS SPAP_1300 NC_014494.1 1236660 1239836 R Operon 583 Gene 1 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); carbamoylphosphate synthase large subunit complement(1236660..1239836) Streptococcus pneumoniae AP200 9727315 YP_003876890.1 CDS SPAP_1301 NC_014494.1 1240148 1241227 R Operon 584 Gene 1 COG0505 Carbamoylphosphate synthase small subunit; carbamoylphosphate synthase small subunit complement(1240148..1241227) Streptococcus pneumoniae AP200 9727316 YP_003876891.1 CDS SPAP_1302 NC_014494.1 1241277 1242200 R Operon 584 Gene 2 COG0540 Aspartate carbamoyltransferase, catalytic chain; aspartate carbamoyltransferase catalytic chain complement(1241277..1242200) Streptococcus pneumoniae AP200 9727317 YP_003876892.1 CDS SPAP_1303 NC_014494.1 1242219 1242740 R Operon 584 Gene 3 COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; pyrimidine operon attenuation protein/uracil phosphoribosyltransferase complement(1242219..1242740) Streptococcus pneumoniae AP200 9727318 YP_003876893.1 CDS SPAP_1304 NC_014494.1 1242951 1243580 R Operon 585 Gene 1 COG0177 Predicted EndoIII-related endonuclease; putative EndoIII-related endonuclease complement(1242951..1243580) Streptococcus pneumoniae AP200 9727319 YP_003876894.1 CDS SPAP_1305 NC_014494.1 1243580 1244122 R Operon 585 Gene 2 COG1399 Predicted metal-binding, possibly nucleic acid-binding protein; putative metal-binding, possibly nucleic acid-binding protein complement(1243580..1244122) Streptococcus pneumoniae AP200 9727320 YP_003876895.1 CDS SPAP_1306 NC_014494.1 1244292 1244609 D Operon 586 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1244292..1244609 Streptococcus pneumoniae AP200 9727321 YP_003876896.1 CDS SPAP_1307 NC_014494.1 1244577 1244786 R Operon 587 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1244577..1244786) Streptococcus pneumoniae AP200 9727322 YP_003876897.1 CDS SPAP_1308 NC_014494.1 1244848 1246407 D Operon 588 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 1244848..1246407 Streptococcus pneumoniae AP200 9727323 YP_003876898.1 CDS SPAP_1309 NC_014494.1 1246451 1247350 R Operon 589 Gene 1 COG0501 Zn-dependent protease with chaperone function; Zn-dependent protease with chaperone function complement(1246451..1247350) Streptococcus pneumoniae AP200 9727324 YP_003876899.1 CDS SPAP_1310 NC_014494.1 1247352 1247912 R Operon 589 Gene 2 COG1704 Uncharacterized conserved protein; hypothetical protein complement(1247352..1247912) Streptococcus pneumoniae AP200 9727325 YP_003876900.1 CDS SPAP_1311 NC_014494.1 1248006 1248719 D Operon 590 Gene 1 COG0357 Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division; putative S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division 1248006..1248719 Streptococcus pneumoniae AP200 9727326 YP_003876901.1 CDS SPAP_1312 NC_014494.1 1248952 1250256 D Operon 590 Gene 2 protein supported gi|168182407|ref|ZP_02617071.1| 50S ribosomal protein L18; hypothetical protein 1248952..1250256 Streptococcus pneumoniae AP200 9727327 YP_003876902.1 CDS SPAP_1313 NC_014494.1 1250451 1252022 R Operon 591 Gene 1 COG0541 Signal recognition particle GTPase; signal recognition particle GTPase complement(1250451..1252022) Streptococcus pneumoniae AP200 9727328 YP_003876903.1 CDS SPAP_1314 NC_014494.1 1252034 1252366 R Operon 591 Gene 2 COG2739 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1252034..1252366) Streptococcus pneumoniae AP200 9727329 YP_003876904.1 CDS SPAP_1315 NC_014494.1 1252457 1252834 R Operon 591 Gene 3 protein supported gi|149007043|ref|ZP_01830712.1| 50S ribosomal protein L19; hypothetical protein complement(1252457..1252834) Streptococcus pneumoniae AP200 9727330 YP_003876905.1 CDS SPAP_1316 NC_014494.1 1252906 1254210 D Operon 592 Gene 1 COG1078 HD superfamily phosphohydrolases; HD superfamily phosphohydrolase 1252906..1254210 Streptococcus pneumoniae AP200 9727331 YP_003876906.1 CDS SPAP_1317 NC_014494.1 1254223 1255029 D Operon 592 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase 1254223..1255029 Streptococcus pneumoniae AP200 9727332 YP_003876907.1 CDS SPAP_1318 NC_014494.1 1255072 1256070 D Operon 592 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1255072..1256070 Streptococcus pneumoniae AP200 9727333 YP_003876908.1 CDS SPAP_1320 NC_014494.1 1256351 1256698 R Operon 593 Gene 1 protein supported gi|15901153|ref|NP_345757.1| 50S ribosomal protein L19; hypothetical protein complement(1256351..1256698) Streptococcus pneumoniae AP200 9727335 YP_003876909.1 CDS SPAP_1321 NC_014494.1 1256817 1257146 R Operon 594 Gene 1 COG0239 Integral membrane protein possibly involved in chromosome condensation; integral membrane protein complement(1256817..1257146) Streptococcus pneumoniae AP200 9727336 YP_003876910.1 CDS SPAP_1322 NC_014494.1 1257140 1257514 R Operon 594 Gene 2 protein supported gi|15901155|ref|NP_345759.1| chromosome condensation/camphor resistance protein CrcB; hypothetical protein complement(1257140..1257514) Streptococcus pneumoniae AP200 9727337 YP_003876911.1 CDS SPAP_1323 NC_014494.1 1257511 1257777 R Operon 594 Gene 3 COG1605 Chorismate mutase; chorismate mutase complement(1257511..1257777) Streptococcus pneumoniae AP200 9727338 YP_003876912.1 CDS SPAP_1324 NC_014494.1 1257893 1258336 R Operon 595 Gene 1 COG0716 Flavodoxins; flavodoxin complement(1257893..1258336) Streptococcus pneumoniae AP200 9727339 YP_003876913.1 CDS SPAP_1325 NC_014494.1 1258440 1259375 D Operon 596 Gene 1 protein supported gi|149007035|ref|ZP_01830704.1| 50S ribosomal protein L31 type B; hypothetical protein 1258440..1259375 Streptococcus pneumoniae AP200 9727340 YP_003876914.1 CDS SPAP_1326 NC_014494.1 1259429 1259713 D Operon 596 Gene 2 protein supported gi|111658525|ref|ZP_01409191.1| hypothetical protein SpneT_02000352; hypothetical protein 1259429..1259713 Streptococcus pneumoniae AP200 9727341 YP_003876915.1 CDS SPAP_1327 NC_014494.1 1259770 1259988 R Operon 597 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1259770..1259988) Streptococcus pneumoniae AP200 9727342 YP_003876916.1 CDS SPAP_1328 NC_014494.1 1260296 1260547 R transposase-like protein, ISSpn2 complement(1260296..1260547) Streptococcus pneumoniae AP200 9727343 YP_003876917.1 CDS SPAP_1329 NC_014494.1 1260641 1260736 R transposase-like protein, ISSpn2 complement(1260641..1260736) Streptococcus pneumoniae AP200 9727344 YP_003876918.1 CDS SPAP_1330 NC_014494.1 1261073 1262419 D Operon 599 Gene 1 COG0334 Glutamate dehydrogenase/leucine dehydrogenase; glutamate dehydrogenase/leucine dehydrogenase 1261073..1262419 Streptococcus pneumoniae AP200 9727345 YP_003876919.1 CDS SPAP_1331 NC_014494.1 1262925 1263095 R Operon 600 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1262925..1263095) Streptococcus pneumoniae AP200 9727346 YP_003876920.1 CDS SPAP_1332 NC_014494.1 1263108 1263554 R Operon 600 Gene 2 COG2274 ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain; bacteriocin/lantibiotic ABC exporter complement(1263108..1263554) Streptococcus pneumoniae AP200 9727347 YP_003876921.1 CDS SPAP_1333 NC_014494.1 1263703 1264092 R transposase-like protein, IS1381 ISSpn7 complement(1263703..1264092) Streptococcus pneumoniae AP200 9727348 YP_003876922.1 CDS SPAP_1334 NC_014494.1 1264185 1264508 R transposase-like protein, IS1381 ISSpn7 complement(1264185..1264508) Streptococcus pneumoniae AP200 9727349 YP_003876923.1 CDS SPAP_1335 NC_014494.1 1264764 1264994 D transposase-like protein, ISSpn2 1264764..1264994 Streptococcus pneumoniae AP200 9727350 YP_003876924.1 CDS SPAP_1336 NC_014494.1 1264942 1265463 D Operon 602 Gene 2 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 1264942..1265463 Streptococcus pneumoniae AP200 9727351 YP_003876925.1 CDS SPAP_1337 NC_014494.1 1265734 1266030 R Operon 603 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1265734..1266030) Streptococcus pneumoniae AP200 9727352 YP_003876926.1 CDS SPAP_1338 NC_014494.1 1266043 1266186 R Operon 603 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1266043..1266186) Streptococcus pneumoniae AP200 9727353 YP_003876927.1 CDS SPAP_1339 NC_014494.1 1266188 1266475 R Operon 603 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1266188..1266475) Streptococcus pneumoniae AP200 9727354 YP_003876928.1 CDS SPAP_1340 NC_014494.1 1267060 1267563 D Operon 604 Gene 1 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1267060..1267563 Streptococcus pneumoniae AP200 9727355 YP_003876929.1 CDS SPAP_1341 NC_014494.1 1267572 1268411 D Operon 604 Gene 2 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 1267572..1268411 Streptococcus pneumoniae AP200 9727356 YP_003876930.1 CDS SPAP_1342 NC_014494.1 1268718 1268921 R Operon 605 Gene 1 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase complement(1268718..1268921) Streptococcus pneumoniae AP200 9727357 YP_003876931.1 CDS SPAP_1343 NC_014494.1 1268997 1269608 R Operon 605 Gene 2 COG1394 Archaeal/vacuolar-type H+-ATPase subunit D; archaeal/vacuolar-type H+-ATPase subunit D complement(1268997..1269608) Streptococcus pneumoniae AP200 9727358 YP_003876932.1 CDS SPAP_1344 NC_014494.1 1269631 1271016 R Operon 605 Gene 3 COG1156 Archaeal/vacuolar-type H+-ATPase subunit B; archaeal/vacuolar-type H+-ATPase subunit B complement(1269631..1271016) Streptococcus pneumoniae AP200 9727359 YP_003876933.1 CDS SPAP_1345 NC_014494.1 1271017 1272792 R Operon 605 Gene 4 COG1155 Archaeal/vacuolar-type H+-ATPase subunit A; archaeal/vacuolar-type H+-ATPase subunit a complement(1271017..1272792) Streptococcus pneumoniae AP200 9727360 YP_003876934.1 CDS SPAP_1346 NC_014494.1 1272855 1273175 R Operon 605 Gene 5 COG1436 Archaeal/vacuolar-type H+-ATPase subunit F; archaeal/vacuolar-type H+-ATPase subunit F complement(1272855..1273175) Streptococcus pneumoniae AP200 9727361 YP_003876935.1 CDS SPAP_1347 NC_014494.1 1273165 1274172 R Operon 605 Gene 6 COG1527 Archaeal/vacuolar-type H+-ATPase subunit C; archaeal/vacuolar-type H+-ATPase subunit C complement(1273165..1274172) Streptococcus pneumoniae AP200 9727362 YP_003876936.1 CDS SPAP_1348 NC_014494.1 1274237 1274818 R Operon 605 Gene 7 Putative gene predicted by FgenesB; hypothetical protein complement(1274237..1274818) Streptococcus pneumoniae AP200 9727363 YP_003876937.1 CDS SPAP_1349 NC_014494.1 1274852 1275328 R Operon 605 Gene 8 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K complement(1274852..1275328) Streptococcus pneumoniae AP200 9727364 YP_003876938.1 CDS SPAP_1350 NC_014494.1 1275385 1277334 R Operon 605 Gene 9 COG1269 Archaeal/vacuolar-type H+-ATPase subunit I; archaeal/vacuolar-type H+-ATPase subunit I complement(1275385..1277334) Streptococcus pneumoniae AP200 9727365 YP_003876939.1 CDS SPAP_1351 NC_014494.1 1277324 1277647 R Operon 605 Gene 10 Putative gene predicted by FgenesB; hypothetical protein complement(1277324..1277647) Streptococcus pneumoniae AP200 9727366 YP_003876940.1 CDS SPAP_1352 NC_014494.1 1277672 1278562 R Operon 605 Gene 11 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase complement(1277672..1278562) Streptococcus pneumoniae AP200 9727367 YP_003876941.1 CDS SPAP_1353 NC_014494.1 1278719 1279828 R Operon 606 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein complement(1278719..1279828) Streptococcus pneumoniae AP200 9727368 YP_003876942.1 CDS SPAP_1354 NC_014494.1 1279868 1282090 R Operon 606 Gene 2 COG4409 Neuraminidase (sialidase); neuraminidase complement(1279868..1282090) Streptococcus pneumoniae AP200 9727369 YP_003876943.1 CDS SPAP_1355 NC_014494.1 1282092 1282550 R Operon 606 Gene 3 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta complement(1282092..1282550) Streptococcus pneumoniae AP200 9727370 YP_003876944.1 CDS SPAP_1356 NC_014494.1 1282569 1284110 R Operon 606 Gene 4 COG0591 Na+/proline symporter; Na+/proline symporter complement(1282569..1284110) Streptococcus pneumoniae AP200 9727371 YP_003876945.1 CDS SPAP_1357 NC_014494.1 1284138 1285055 R Operon 606 Gene 5 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase complement(1284138..1285055) Streptococcus pneumoniae AP200 9727372 YP_003876946.1 CDS SPAP_1358 NC_014494.1 1285080 1285781 R Operon 606 Gene 6 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; putative N-acetylmannosamine-6-phosphate epimerase complement(1285080..1285781) Streptococcus pneumoniae AP200 9727373 YP_003876947.1 CDS SPAP_1359 NC_014494.1 1285786 1286595 R Operon 606 Gene 7 COG1737 Transcriptional regulators; transcriptional regulator complement(1285786..1286595) Streptococcus pneumoniae AP200 9727374 YP_003876948.1 CDS SPAP_1360 NC_014494.1 1287229 1287585 R Operon 607 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease complement(1287229..1287585) Streptococcus pneumoniae AP200 9727375 YP_003876949.1 CDS SPAP_1361 NC_014494.1 1287678 1287821 R Operon 607 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1287678..1287821) Streptococcus pneumoniae AP200 9727376 YP_003876950.1 CDS SPAP_1362 NC_014494.1 1287834 1288214 R Operon 607 Gene 3 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein complement(1287834..1288214) Streptococcus pneumoniae AP200 9727377 YP_003876951.1 CDS SPAP_1363 NC_014494.1 1288372 1288557 R Operon 608 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1288372..1288557) Streptococcus pneumoniae AP200 9727378 YP_003876952.1 CDS SPAP_1364 NC_014494.1 1288778 1289956 R Operon 609 Gene 1 COG0270 Site-specific DNA methylase; site-specific DNA methylase complement(1288778..1289956) Streptococcus pneumoniae AP200 9727379 YP_003876953.1 CDS SPAP_1365 NC_014494.1 1290183 1290524 R transposase-like protein, IS1380 ISSpn5 complement(1290183..1290524) Streptococcus pneumoniae AP200 9727380 YP_003876954.1 CDS SPAP_1366 NC_014494.1 1290499 1290876 R transposase-like protein, IS1380 ISSpn5 complement(1290499..1290876) Streptococcus pneumoniae AP200 9727381 YP_003876955.1 CDS SPAP_1367 NC_014494.1 1291111 1291377 R Operon 611 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1291111..1291377) Streptococcus pneumoniae AP200 9727382 YP_003876956.1 CDS SPAP_1368 NC_014494.1 1291280 1291534 R transposase-like protein, IS1380 ISSpn5 complement(1291280..1291534) Streptococcus pneumoniae AP200 9727383 YP_003876957.1 CDS SPAP_1369 NC_014494.1 1291796 1291975 R Operon 612 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1291796..1291975) Streptococcus pneumoniae AP200 9727384 YP_003876958.1 CDS SPAP_1370 NC_014494.1 1292155 1292292 R Operon 613 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1292155..1292292) Streptococcus pneumoniae AP200 9727385 YP_003876959.1 CDS SPAP_1371 NC_014494.1 1292425 1293744 R Operon 614 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1292425..1293744) Streptococcus pneumoniae AP200 9727386 YP_003876960.1 CDS SPAP_1372 NC_014494.1 1293747 1294487 R Operon 614 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase complement(1293747..1294487) Streptococcus pneumoniae AP200 9727387 YP_003876961.1 CDS SPAP_1373 NC_014494.1 1294502 1296109 R Operon 614 Gene 3 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1294502..1296109) Streptococcus pneumoniae AP200 9727388 YP_003876962.1 CDS SPAP_1374 NC_014494.1 1296106 1296900 R Operon 614 Gene 4 COG1770 Protease II; protease II complement(1296106..1296900) Streptococcus pneumoniae AP200 9727389 YP_003876963.1 CDS SPAP_1375 NC_014494.1 1298079 1300577 R Operon 615 Gene 1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase complement(1298079..1300577) Streptococcus pneumoniae AP200 9727390 YP_003876964.1 CDS SPAP_1376 NC_014494.1 1300867 1301004 R Operon 616 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1300867..1301004) Streptococcus pneumoniae AP200 9727391 YP_003876965.1 CDS SPAP_1377 NC_014494.1 1301206 1301448 R Operon 617 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease complement(1301206..1301448) Streptococcus pneumoniae AP200 9727392 YP_003876966.1 CDS SPAP_1378 NC_014494.1 1301600 1301791 R Operon 618 Gene 1 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease complement(1301600..1301791) Streptococcus pneumoniae AP200 9727393 YP_003876967.1 CDS SPAP_1379 NC_014494.1 1301884 1302027 R Operon 618 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1301884..1302027) Streptococcus pneumoniae AP200 9727394 YP_003876968.1 CDS SPAP_1380 NC_014494.1 1302040 1302420 R Operon 618 Gene 3 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein complement(1302040..1302420) Streptococcus pneumoniae AP200 9727395 YP_003876969.1 CDS SPAP_1381 NC_014494.1 1302413 1302664 R Operon 618 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1302413..1302664) Streptococcus pneumoniae AP200 9727396 YP_003876970.1 CDS SPAP_1382 NC_014494.1 1302744 1302998 R Operon 618 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(1302744..1302998) Streptococcus pneumoniae AP200 9727397 YP_003876971.1 CDS SPAP_1383 NC_014494.1 1302998 1303168 R Operon 618 Gene 6 Putative gene predicted by FgenesB; hypothetical protein complement(1302998..1303168) Streptococcus pneumoniae AP200 9727398 YP_003876972.1 CDS SPAP_1384 NC_014494.1 1303354 1303737 R Operon 619 Gene 1 protein supported gi|15458846|gb|AAL00015.1| 50S Ribosomal protein L12; hypothetical protein complement(1303354..1303737) Streptococcus pneumoniae AP200 9727399 YP_003876973.1 CDS SPAP_1385 NC_014494.1 1303798 1304361 R Operon 619 Gene 2 protein supported gi|182684314|ref|YP_001836061.1| 50S ribosomal protein L10; hypothetical protein complement(1303798..1304361) Streptococcus pneumoniae AP200 9727400 YP_003876974.1 CDS SPAP_1386 NC_014494.1 1304548 1305807 R Operon 620 Gene 1 COG0402 Cytosine deaminase and related metal-dependent hydrolases; cytosine deaminase-like metal-dependent hydrolase complement(1304548..1305807) Streptococcus pneumoniae AP200 9727401 YP_003876975.1 CDS SPAP_1387 NC_014494.1 1306109 1307857 R Operon 621 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1306109..1307857) Streptococcus pneumoniae AP200 9727402 YP_003876976.1 CDS SPAP_1388 NC_014494.1 1307859 1309583 R Operon 621 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1307859..1309583) Streptococcus pneumoniae AP200 9727403 YP_003876977.1 CDS SPAP_1389 NC_014494.1 1309641 1310579 R Operon 621 Gene 3 COG0225 Peptide methionine sulfoxide reductase; peptide methionine sulfoxide reductase complement(1309641..1310579) Streptococcus pneumoniae AP200 9727404 YP_003876978.1 CDS SPAP_1390 NC_014494.1 1310919 1311788 R Operon 622 Gene 1 COG0083 Homoserine kinase; homoserine kinase complement(1310919..1311788) Streptococcus pneumoniae AP200 9727405 YP_003876979.1 CDS SPAP_1391 NC_014494.1 1311790 1313076 R Operon 622 Gene 2 COG0460 Homoserine dehydrogenase; homoserine dehydrogenase complement(1311790..1313076) Streptococcus pneumoniae AP200 9727406 YP_003876980.1 CDS SPAP_1392 NC_014494.1 1313227 1313964 R Operon 623 Gene 1 COG4862 Negative regulator of genetic competence, sporulation and motility; Negative regulator of genetic competence, sporulation and motility complement(1313227..1313964) Streptococcus pneumoniae AP200 9727407 YP_003876981.1 CDS SPAP_1393 NC_014494.1 1314164 1315198 R Operon 624 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1314164..1315198) Streptococcus pneumoniae AP200 9727408 YP_003876982.1 CDS SPAP_1394 NC_014494.1 1315227 1316534 R Operon 624 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1315227..1316534) Streptococcus pneumoniae AP200 9727409 YP_003876983.1 CDS SPAP_1395 NC_014494.1 1316676 1317662 R Operon 625 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase complement(1316676..1317662) Streptococcus pneumoniae AP200 9727410 YP_003876984.1 CDS SPAP_1396 NC_014494.1 1317664 1318764 R Operon 625 Gene 2 COG0438 Glycosyltransferase; glycosyltransferase complement(1317664..1318764) Streptococcus pneumoniae AP200 9727411 YP_003876985.1 CDS SPAP_1397 NC_014494.1 1318757 1319593 R Operon 625 Gene 3 COG3475 LPS biosynthesis protein; LPS biosynthesis protein complement(1318757..1319593) Streptococcus pneumoniae AP200 9727412 YP_003876986.1 CDS SPAP_1398 NC_014494.1 1319881 1321155 R Operon 626 Gene 1 COG1316 Transcriptional regulator; transcriptional regulator complement(1319881..1321155) Streptococcus pneumoniae AP200 9727413 YP_003876987.1 CDS SPAP_1399 NC_014494.1 1321152 1322000 R Operon 626 Gene 2 COG0077 Prephenate dehydratase; prephenate dehydratase complement(1321152..1322000) Streptococcus pneumoniae AP200 9727414 YP_003876988.1 CDS SPAP_1400 NC_014494.1 1321997 1322473 R Operon 626 Gene 3 COG0703 Shikimate kinase; shikimate kinase complement(1321997..1322473) Streptococcus pneumoniae AP200 9727415 YP_003876989.1 CDS SPAP_1401 NC_014494.1 1322466 1323761 R Operon 626 Gene 4 COG0128 5-enolpyruvylshikimate-3-phosphate synthase; 5-enolpyruvylshikimate-3-phosphate synthase complement(1322466..1323761) Streptococcus pneumoniae AP200 9727416 YP_003876990.1 CDS SPAP_1402 NC_014494.1 1323841 1324002 R Operon 627 Gene 1 COG3679 Uncharacterized conserved protein; hypothetical protein complement(1323841..1324002) Streptococcus pneumoniae AP200 9727417 YP_003876991.1 CDS SPAP_1403 NC_014494.1 1324003 1324179 R Operon 627 Gene 2 COG3679 Uncharacterized conserved protein; hypothetical protein complement(1324003..1324179) Streptococcus pneumoniae AP200 9727418 YP_003876992.1 CDS SPAP_1404 NC_014494.1 1324190 1325293 R Operon 627 Gene 3 COG0287 Prephenate dehydrogenase; prephenate dehydrogenase complement(1324190..1325293) Streptococcus pneumoniae AP200 9727419 YP_003876993.1 CDS SPAP_1405 NC_014494.1 1325303 1326469 R Operon 627 Gene 4 COG0082 Chorismate synthase; chorismate synthase complement(1325303..1326469) Streptococcus pneumoniae AP200 9727420 YP_003876994.1 CDS SPAP_1406 NC_014494.1 1326479 1327546 R Operon 627 Gene 5 COG0337 3-dehydroquinate synthetase; 3-dehydroquinate synthetase complement(1326479..1327546) Streptococcus pneumoniae AP200 9727421 YP_003876995.1 CDS SPAP_1407 NC_014494.1 1327565 1328419 R Operon 627 Gene 6 COG0169 Shikimate 5-dehydrogenase; shikimate 5-dehydrogenase complement(1327565..1328419) Streptococcus pneumoniae AP200 9727422 YP_003876996.1 CDS SPAP_1408 NC_014494.1 1328409 1329086 R Operon 627 Gene 7 COG0710 3-dehydroquinate dehydratase; 3-dehydroquinate dehydratase complement(1328409..1329086) Streptococcus pneumoniae AP200 9727423 YP_003876997.1 CDS SPAP_1409 NC_014494.1 1329083 1330255 R Operon 627 Gene 8 COG1092 Predicted SAM-dependent methyltransferases; putative SAM-dependent methyltransferase complement(1329083..1330255) Streptococcus pneumoniae AP200 9727424 YP_003876998.1 CDS SPAP_1410 NC_014494.1 1330930 1332564 R Operon 628 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1330930..1332564) Streptococcus pneumoniae AP200 9727425 YP_003876999.1 CDS SPAP_1411 NC_014494.1 1332545 1333294 R Operon 628 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase complement(1332545..1333294) Streptococcus pneumoniae AP200 9727426 YP_003877000.1 CDS SPAP_1412 NC_014494.1 1333473 1334927 D Operon 629 Gene 1 COG0366 Glycosidases; glycosidase 1333473..1334927 Streptococcus pneumoniae AP200 9727427 YP_003877001.1 CDS SPAP_1413 NC_014494.1 1335017 1337635 R Operon 630 Gene 1 COG0013 Alanyl-tRNA synthetase; alanyl-tRNa synthetase complement(1335017..1337635) Streptococcus pneumoniae AP200 9727428 YP_003877002.1 CDS SPAP_1414 NC_014494.1 1337657 1338142 R Operon 630 Gene 2 COG4894 Uncharacterized conserved protein; hypothetical protein complement(1337657..1338142) Streptococcus pneumoniae AP200 9727429 YP_003877003.1 CDS SPAP_1415 NC_014494.1 1338417 1338656 R Operon 631 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1338417..1338656) Streptococcus pneumoniae AP200 9727430 YP_003877004.1 CDS SPAP_1416 NC_014494.1 1338714 1339346 R Operon 631 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 complement(1338714..1339346) Streptococcus pneumoniae AP200 9727431 YP_003877005.1 CDS SPAP_1417 NC_014494.1 1339793 1340863 R Operon 632 Gene 1 COG0687 Spermidine/putrescine-binding periplasmic protein; spermidine/putrescine-binding periplasmic protein complement(1339793..1340863) Streptococcus pneumoniae AP200 9727432 YP_003877006.1 CDS SPAP_1418 NC_014494.1 1340860 1341633 R Operon 632 Gene 2 COG1177 ABC-type spermidine/putrescine transport system, permease component II; spermidine/putrescine ABC transporter permease II complement(1340860..1341633) Streptococcus pneumoniae AP200 9727433 YP_003877007.1 CDS SPAP_1419 NC_014494.1 1341630 1342436 R Operon 632 Gene 3 COG1176 ABC-type spermidine/putrescine transport system, permease component I; spermidine/putrescine ABC transporter permease I complement(1341630..1342436) Streptococcus pneumoniae AP200 9727434 YP_003877008.1 CDS SPAP_1420 NC_014494.1 1342417 1343574 R Operon 632 Gene 4 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase complement(1342417..1343574) Streptococcus pneumoniae AP200 9727435 YP_003877009.1 CDS SPAP_1421 NC_014494.1 1343633 1344583 R Operon 632 Gene 5 COG0812 UDP-N-acetylmuramate dehydrogenase; UDP-N-acetylmuramate dehydrogenase complement(1343633..1344583) Streptococcus pneumoniae AP200 9727436 YP_003877010.1 CDS SPAP_1422 NC_014494.1 1344695 1345246 R Operon 633 Gene 1 COG4377 Predicted membrane protein; hypothetical protein complement(1344695..1345246) Streptococcus pneumoniae AP200 9727437 YP_003877011.1 CDS SPAP_1423 NC_014494.1 1345257 1345448 R Operon 633 Gene 2 COG4377 Predicted membrane protein; hypothetical protein complement(1345257..1345448) Streptococcus pneumoniae AP200 9727438 YP_003877012.1 CDS SPAP_1424 NC_014494.1 1345458 1346189 R Operon 633 Gene 3 COG3527 Alpha-acetolactate decarboxylase; alpha-acetolactate decarboxylase complement(1345458..1346189) Streptococcus pneumoniae AP200 9727439 YP_003877013.1 CDS SPAP_1425 NC_014494.1 1346331 1347602 D Operon 634 Gene 1 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; MocR family transcriptional regulator 1346331..1347602 Streptococcus pneumoniae AP200 9727440 YP_003877014.1 CDS SPAP_1426 NC_014494.1 1347622 1348437 R Operon 635 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(1347622..1348437) Streptococcus pneumoniae AP200 9727441 YP_003877015.1 CDS SPAP_1427 NC_014494.1 1348594 1349247 R Operon 636 Gene 1 COG0704 Phosphate uptake regulator; phosphate uptake regulator complement(1348594..1349247) Streptococcus pneumoniae AP200 9727442 YP_003877016.1 CDS SPAP_1428 NC_014494.1 1349259 1350017 R Operon 636 Gene 2 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase complement(1349259..1350017) Streptococcus pneumoniae AP200 9727443 YP_003877017.1 CDS SPAP_1429 NC_014494.1 1350030 1350833 R Operon 636 Gene 3 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase complement(1350030..1350833) Streptococcus pneumoniae AP200 9727444 YP_003877018.1 CDS SPAP_1430 NC_014494.1 1350844 1351728 R Operon 636 Gene 4 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease complement(1350844..1351728) Streptococcus pneumoniae AP200 9727445 YP_003877019.1 CDS SPAP_1431 NC_014494.1 1351718 1352635 R Operon 636 Gene 5 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease complement(1351718..1352635) Streptococcus pneumoniae AP200 9727446 YP_003877020.1 CDS SPAP_1432 NC_014494.1 1352635 1353513 R Operon 636 Gene 6 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein complement(1352635..1353513) Streptococcus pneumoniae AP200 9727447 YP_003877021.1 CDS SPAP_1433 NC_014494.1 1354087 1355391 R Operon 637 Gene 1 COG0144 tRNA and rRNA cytosine-C5-methylases; tRNA and rRNA cytosine-C5-methylase complement(1354087..1355391) Streptococcus pneumoniae AP200 9727448 YP_003877022.1 CDS SPAP_1434 NC_014494.1 1355392 1356165 R Operon 637 Gene 2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family; fructose-1,6-bisphosphatase-like protein complement(1355392..1356165) Streptococcus pneumoniae AP200 9727449 YP_003877023.1 CDS SPAP_1435 NC_014494.1 1356155 1356433 R Operon 637 Gene 3 COG4476 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1356155..1356433) Streptococcus pneumoniae AP200 9727450 YP_003877024.1 CDS SPAP_1436 NC_014494.1 1356433 1356834 R Operon 637 Gene 4 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein complement(1356433..1356834) Streptococcus pneumoniae AP200 9727451 YP_003877025.1 CDS SPAP_1437 NC_014494.1 1357044 1357661 R Operon 638 Gene 1 COG4478 Predicted membrane protein; hypothetical protein complement(1357044..1357661) Streptococcus pneumoniae AP200 9727452 YP_003877026.1 CDS SPAP_1438 NC_014494.1 1357651 1358424 R Operon 638 Gene 2 COG0647 Predicted sugar phosphatases of the HAD superfamily; putative sugar phosphatase complement(1357651..1358424) Streptococcus pneumoniae AP200 9727453 YP_003877027.1 CDS SPAP_1439 NC_014494.1 1358435 1359172 R Operon 638 Gene 3 COG3884 Acyl-ACP thioesterase; acyl-ACP thioesterase complement(1358435..1359172) Streptococcus pneumoniae AP200 9727454 YP_003877028.1 CDS SPAP_1440 NC_014494.1 1359177 1360307 R Operon 638 Gene 4 COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductases; coproporphyrinogen III oxidase-like Fe-S oxidoreductases complement(1359177..1360307) Streptococcus pneumoniae AP200 9727455 YP_003877029.1 CDS SPAP_1441 NC_014494.1 1360391 1360780 R Operon 639 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1360391..1360780) Streptococcus pneumoniae AP200 9727456 YP_003877030.1 CDS SPAP_1442 NC_014494.1 1360796 1361179 R Operon 639 Gene 2 COG4768 Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain; hypothetical protein complement(1360796..1361179) Streptococcus pneumoniae AP200 9727457 YP_003877031.1 CDS SPAP_1443 NC_014494.1 1361180 1361968 R Operon 639 Gene 3 COG0682 Prolipoprotein diacylglyceryltransferase; prolipoprotein diacylglyceryltransferase complement(1361180..1361968) Streptococcus pneumoniae AP200 9727458 YP_003877032.1 CDS SPAP_1444 NC_014494.1 1361961 1362896 R Operon 639 Gene 4 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism; serine kinase of the HPr protein, regulates carbohydrate metabolism complement(1361961..1362896) Streptococcus pneumoniae AP200 9727459 YP_003877033.1 CDS SPAP_1445 NC_014494.1 1363026 1363226 R Operon 640 Gene 1 protein supported gi|15903314|ref|NP_358864.1| 30S ribosomal protein S21; hypothetical protein complement(1363026..1363226) Streptococcus pneumoniae AP200 9727460 YP_003877034.1 CDS SPAP_1446 NC_014494.1 1363342 1364064 R Operon 641 Gene 1 COG0363 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase; 6-phosphogluconolactonase/Glucosamine-6- phosphate isomerase/deaminase complement(1363342..1364064) Streptococcus pneumoniae AP200 9727461 YP_003877035.1 CDS SPAP_1447 NC_014494.1 1364188 1365228 D Operon 642 Gene 1 COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); S-adenosylmethionine:tRNA-ribosyltransferase- isomerase 1364188..1365228 Streptococcus pneumoniae AP200 9727462 YP_003877036.1 CDS SPAP_1448 NC_014494.1 1365777 1366166 R Operon 643 Gene 1 COG5263 FOG: choline binding protein; choline binding protein complement(1365777..1366166) Streptococcus pneumoniae AP200 9727463 YP_003877037.1 CDS SPAP_1449 NC_014494.1 1366901 1367002 R Operon 644 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1366901..1367002) Streptococcus pneumoniae AP200 9727464 YP_003877038.1 CDS SPAP_1450 NC_014494.1 1367620 1368171 R Operon 645 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase complement(1367620..1368171) Streptococcus pneumoniae AP200 9727465 YP_003877039.1 CDS SPAP_1451 NC_014494.1 1368418 1369242 R Operon 646 Gene 1 COG0171 NAD synthase; NAD synthase complement(1368418..1369242) Streptococcus pneumoniae AP200 9727466 YP_003877040.1 CDS SPAP_1452 NC_014494.1 1369239 1370699 R Operon 646 Gene 2 COG1488 Nicotinic acid phosphoribosyltransferase; nicotinic acid phosphoribosyltransferase complement(1369239..1370699) Streptococcus pneumoniae AP200 9727467 YP_003877041.1 CDS SPAP_1453 NC_014494.1 1370815 1371303 R Operon 647 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1370815..1371303) Streptococcus pneumoniae AP200 9727468 YP_003877042.1 CDS SPAP_1454 NC_014494.1 1371293 1371502 R Operon 647 Gene 2 COG1476 Predicted transcriptional regulators; putative transcriptional regulator complement(1371293..1371502) Streptococcus pneumoniae AP200 9727469 YP_003877043.1 CDS SPAP_1455 NC_014494.1 1371966 1372616 R Operon 648 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1371966..1372616) Streptococcus pneumoniae AP200 9727470 YP_003877044.1 CDS SPAP_1456 NC_014494.1 1372632 1373351 R Operon 648 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase complement(1372632..1373351) Streptococcus pneumoniae AP200 9727471 YP_003877045.1 CDS SPAP_1457 NC_014494.1 1373858 1374583 R Operon 649 Gene 1 COG0826 Collagenase and related proteases; collagenase-like protease complement(1373858..1374583) Streptococcus pneumoniae AP200 9727472 YP_003877046.1 CDS SPAP_1458 NC_014494.1 1374846 1375157 R Operon 650 Gene 1 COG4357 Uncharacterized conserved protein; hypothetical protein complement(1374846..1375157) Streptococcus pneumoniae AP200 9727473 YP_003877047.1 CDS SPAP_1459 NC_014494.1 1375172 1376458 R Operon 650 Gene 2 COG0826 Collagenase and related proteases; collagenase-like protease complement(1375172..1376458) Streptococcus pneumoniae AP200 9727474 YP_003877048.1 CDS SPAP_1460 NC_014494.1 1377082 1377231 D Operon 651 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1377082..1377231 Streptococcus pneumoniae AP200 9727475 YP_003877049.1 CDS SPAP_1461 NC_014494.1 1377448 1377639 D Operon 652 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1377448..1377639 Streptococcus pneumoniae AP200 9727476 YP_003877050.1 CDS SPAP_1462 NC_014494.1 1377636 1378826 D Operon 652 Gene 2 COG2189 Adenine specific DNA methylase Mod; adenine specific DNa methylase Mod 1377636..1378826 Streptococcus pneumoniae AP200 9727477 YP_003877051.1 CDS SPAP_1463 NC_014494.1 1379073 1379219 D Operon 653 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1379073..1379219 Streptococcus pneumoniae AP200 9727478 YP_003877052.1 CDS SPAP_1464 NC_014494.1 1379341 1380333 R Operon 654 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein complement(1379341..1380333) Streptococcus pneumoniae AP200 9727479 YP_003877053.1 CDS SPAP_1465 NC_014494.1 1380493 1382247 D Operon 655 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1380493..1382247 Streptococcus pneumoniae AP200 9727480 YP_003877054.1 CDS SPAP_1466 NC_014494.1 1382231 1383952 D Operon 655 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease 1382231..1383952 Streptococcus pneumoniae AP200 9727481 YP_003877055.1 CDS SPAP_1467 NC_014494.1 1383963 1384547 D Operon 655 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1383963..1384547 Streptococcus pneumoniae AP200 9727482 YP_003877056.1 CDS SPAP_1468 NC_014494.1 1384547 1385242 D Operon 655 Gene 4 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter 1384547..1385242 Streptococcus pneumoniae AP200 9727483 YP_003877057.1 CDS SPAP_1469 NC_014494.1 1385836 1386594 D Operon 655 Gene 5 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase 1385836..1386594 Streptococcus pneumoniae AP200 9727484 YP_003877058.1 CDS SPAP_1470 NC_014494.1 1387382 1387771 R Operon 656 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_3 complement(1387382..1387771) Streptococcus pneumoniae AP200 9727485 YP_003877059.1 CDS SPAP_1471 NC_014494.1 1388142 1388447 R Operon 657 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_3 complement(1388142..1388447) Streptococcus pneumoniae AP200 9727486 YP_003877060.1 CDS SPAP_1472 NC_014494.1 1388825 1389148 R transposase-like protein, ISSpn_AP200_7 complement(1388825..1389148) Streptococcus pneumoniae AP200 9727487 YP_003877061.1 CDS SPAP_1473 NC_014494.1 1389129 1389314 R Operon 658 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1389129..1389314) Streptococcus pneumoniae AP200 9727488 YP_003877062.1 CDS SPAP_1474 NC_014494.1 1389618 1391180 R Operon 659 Gene 1 COG0519 GMP synthase, PP-ATPase domain/subunit; GMP synthase complement(1389618..1391180) Streptococcus pneumoniae AP200 9727489 YP_003877063.1 CDS SPAP_1475 NC_014494.1 1391322 1392020 D Operon 660 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 1391322..1392020 Streptococcus pneumoniae AP200 9727490 YP_003877064.1 CDS SPAP_1476 NC_014494.1 1392063 1392959 R Operon 661 Gene 1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease complement(1392063..1392959) Streptococcus pneumoniae AP200 9727491 YP_003877065.1 CDS SPAP_1477 NC_014494.1 1392968 1393903 R Operon 661 Gene 2 COG1680 Beta-lactamase class C and other penicillin binding proteins; beta-lactamase class C-like penicillin binding protein complement(1392968..1393903) Streptococcus pneumoniae AP200 9727492 YP_003877066.1 CDS SPAP_1478 NC_014494.1 1393900 1394625 R Operon 661 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1393900..1394625) Streptococcus pneumoniae AP200 9727493 YP_003877067.1 CDS SPAP_1479 NC_014494.1 1394709 1395344 R Operon 662 Gene 1 COG2755 Lysophospholipase L1 and related esterases; lysophospholipase l1-like esterase complement(1394709..1395344) Streptococcus pneumoniae AP200 9727494 YP_003877068.1 CDS SPAP_1480 NC_014494.1 1395346 1396170 R Operon 662 Gene 2 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(1395346..1396170) Streptococcus pneumoniae AP200 9727495 YP_003877069.1 CDS SPAP_1481 NC_014494.1 1396195 1396530 R Operon 662 Gene 3 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamate biosynthesis protein complement(1396195..1396530) Streptococcus pneumoniae AP200 9727496 YP_003877070.1 CDS SPAP_1482 NC_014494.1 1396531 1397043 R Operon 662 Gene 4 COG2843 Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation); poly-gamma-glutamate biosynthesis protein complement(1396531..1397043) Streptococcus pneumoniae AP200 9727497 YP_003877071.1 CDS SPAP_1483 NC_014494.1 1397137 1397259 R Operon 663 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1397137..1397259) Streptococcus pneumoniae AP200 9727498 YP_003877072.1 CDS SPAP_1484 NC_014494.1 1397772 1398383 D Operon 664 Gene 1 COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase 1397772..1398383 Streptococcus pneumoniae AP200 9727499 YP_003877073.1 CDS SPAP_1485 NC_014494.1 1398395 1399156 D Operon 664 Gene 2 protein supported gi|163764761|ref|ZP_02171815.1| ribosomal protein S11; hypothetical protein 1398395..1399156 Streptococcus pneumoniae AP200 9727500 YP_003877074.1 CDS SPAP_1486 NC_014494.1 1399196 1400107 R Operon 665 Gene 1 COG0492 Thioredoxin reductase; thioredoxin reductase complement(1399196..1400107) Streptococcus pneumoniae AP200 9727501 YP_003877075.1 CDS SPAP_1487 NC_014494.1 1400173 1400397 R Operon 665 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1400173..1400397) Streptococcus pneumoniae AP200 9727502 YP_003877076.1 CDS SPAP_1488 NC_014494.1 1400475 1401218 R Operon 666 Gene 1 protein supported gi|163803615|ref|ZP_02197481.1| 50S ribosomal protein L34; hypothetical protein complement(1400475..1401218) Streptococcus pneumoniae AP200 9727503 YP_003877077.1 CDS SPAP_1489 NC_014494.1 1401218 1402018 R Operon 666 Gene 2 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(1401218..1402018) Streptococcus pneumoniae AP200 9727504 YP_003877078.1 CDS SPAP_1490 NC_014494.1 1402176 1402532 R Operon 667 Gene 1 COG1393 Arsenate reductase and related proteins, glutaredoxin family; arsenate reductase-like glutaredoxin family protein complement(1402176..1402532) Streptococcus pneumoniae AP200 9727505 YP_003877079.1 CDS SPAP_1491 NC_014494.1 1402545 1403057 R Operon 667 Gene 2 COG0350 Methylated DNA-protein cysteine methyltransferase; methylated DNA-protein cysteine methyltransferase complement(1402545..1403057) Streptococcus pneumoniae AP200 9727506 YP_003877080.1 CDS SPAP_1492 NC_014494.1 1403057 1403551 R Operon 667 Gene 3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1403057..1403551) Streptococcus pneumoniae AP200 9727507 YP_003877081.1 CDS SPAP_1493 NC_014494.1 1403686 1404132 D Operon 668 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1403686..1404132 Streptococcus pneumoniae AP200 9727508 YP_003877082.1 CDS SPAP_1494 NC_014494.1 1404129 1404776 D Operon 668 Gene 2 COG1272 Predicted membrane protein, hemolysin III homolog; hypothetical protein 1404129..1404776 Streptococcus pneumoniae AP200 9727509 YP_003877083.1 CDS SPAP_1495 NC_014494.1 1404797 1405378 R Operon 669 Gene 1 COG0311 Predicted glutamine amidotransferase involved in pyridoxine biosynthesis; putative glutamine amidotransferase complement(1404797..1405378) Streptococcus pneumoniae AP200 9727510 YP_003877084.1 CDS SPAP_1496 NC_014494.1 1405379 1406254 R Operon 669 Gene 2 COG0214 Pyridoxine biosynthesis enzyme; pyridoxine biosynthesis enzyme complement(1405379..1406254) Streptococcus pneumoniae AP200 9727511 YP_003877085.1 CDS SPAP_1497 NC_014494.1 1406406 1407785 R Operon 670 Gene 1 COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases; hypothetical protein complement(1406406..1407785) Streptococcus pneumoniae AP200 9727512 YP_003877086.1 CDS SPAP_1498 NC_014494.1 1408079 1409002 D Operon 671 Gene 1 COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; membrane-associated lipoprotein involved in thiamine biosynthesis 1408079..1409002 Streptococcus pneumoniae AP200 9727513 YP_003877087.1 CDS SPAP_1499 NC_014494.1 1409062 1409667 D Operon 671 Gene 2 COG0431 Predicted flavoprotein; putative flavoprotein 1409062..1409667 Streptococcus pneumoniae AP200 9727514 YP_003877088.1 CDS SPAP_1500 NC_014494.1 1409686 1410930 D Operon 671 Gene 3 COG2461 Uncharacterized conserved protein; hypothetical protein 1409686..1410930 Streptococcus pneumoniae AP200 9727515 YP_003877089.1 CDS SPAP_1501 NC_014494.1 1411153 1411410 R Operon 672 Gene 1 COG4224 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1411153..1411410) Streptococcus pneumoniae AP200 9727516 YP_003877090.1 CDS SPAP_1502 NC_014494.1 1411452 1413488 R Operon 672 Gene 2 COG0751 Glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta complement(1411452..1413488) Streptococcus pneumoniae AP200 9727517 YP_003877091.1 CDS SPAP_1503 NC_014494.1 1413700 1414617 R Operon 672 Gene 3 COG0752 Glycyl-tRNA synthetase, alpha subunit; glycyl-tRNA synthetase subunit alpha complement(1413700..1414617) Streptococcus pneumoniae AP200 9727518 YP_003877092.1 CDS SPAP_1504 NC_014494.1 1414812 1415573 R Operon 673 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1414812..1415573) Streptococcus pneumoniae AP200 9727519 YP_003877093.1 CDS SPAP_1505 NC_014494.1 1415846 1416688 R Operon 674 Gene 1 COG0656 Aldo/keto reductases, related to diketogulonate reductase; aldo/keto reductase complement(1415846..1416688) Streptococcus pneumoniae AP200 9727520 YP_003877094.1 CDS SPAP_1506 NC_014494.1 1416802 1418193 R Operon 675 Gene 1 COG0726 Predicted xylanase/chitin deacetylase; putative xylanase/chitin deacetylase complement(1416802..1418193) Streptococcus pneumoniae AP200 9727521 YP_003877095.1 CDS SPAP_1507 NC_014494.1 1418428 1418805 R Operon 676 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1418428..1418805) Streptococcus pneumoniae AP200 9727522 YP_003877096.1 CDS SPAP_1508 NC_014494.1 1419020 1419997 D Operon 677 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein 1419020..1419997 Streptococcus pneumoniae AP200 9727523 YP_003877097.1 CDS SPAP_1509 NC_014494.1 1419994 1421076 D Operon 677 Gene 2 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase 1419994..1421076 Streptococcus pneumoniae AP200 9727524 YP_003877098.1 CDS SPAP_1510 NC_014494.1 1421235 1421648 R Operon 678 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 complement(1421235..1421648) Streptococcus pneumoniae AP200 9727525 YP_003877099.1 CDS SPAP_1511 NC_014494.1 1421680 1422033 R transposase-like protein, ISSpn2 complement(1421680..1422033) Streptococcus pneumoniae AP200 9727526 YP_003877100.1 CDS SPAP_1512 NC_014494.1 1422057 1422188 R transposase-like protein, ISSpn2 complement(1422057..1422188) Streptococcus pneumoniae AP200 9727527 YP_003877101.1 CDS SPAP_1513 NC_014494.1 1422572 1423768 R Operon 679 Gene 1 protein supported gi|119502908|ref|ZP_01624993.1| Ribosomal protein S19; hypothetical protein complement(1422572..1423768) Streptococcus pneumoniae AP200 9727528 YP_003877102.1 CDS SPAP_1514 NC_014494.1 1423932 1424885 R transposase-like protein, IS1239 complement(1423932..1424885) Streptococcus pneumoniae AP200 9727529 YP_003877103.1 CDS SPAP_1515 NC_014494.1 1425923 1426792 R Operon 681 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease complement(1425923..1426792) Streptococcus pneumoniae AP200 9727530 YP_003877104.1 CDS SPAP_1516 NC_014494.1 1427016 1427537 R cell wall surface anchor family protein; hypothetical protein complement(1427016..1427537) Streptococcus pneumoniae AP200 9727531 YP_003877105.1 CDS SPAP_1517 NC_014494.1 1427495 1428601 R Operon 682 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1427495..1428601) Streptococcus pneumoniae AP200 9727532 YP_003877106.1 CDS SPAP_1518 NC_014494.1 1428712 1428963 R Operon 683 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1428712..1428963) Streptococcus pneumoniae AP200 9727533 YP_003877107.1 CDS SPAP_1519 NC_014494.1 1429306 1429605 R Operon 684 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_4 complement(1429306..1429605) Streptococcus pneumoniae AP200 9727534 YP_003877108.1 CDS SPAP_1520 NC_014494.1 1429825 1430040 R Operon 685 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1429825..1430040) Streptococcus pneumoniae AP200 9727535 YP_003877109.1 CDS SPAP_1521 NC_014494.1 1430383 1432101 D Operon 686 Gene 1 COG1109 Phosphomannomutase; phosphomannomutase 1430383..1432101 Streptococcus pneumoniae AP200 9727536 YP_003877110.1 CDS SPAP_1522 NC_014494.1 1432212 1432559 D Operon 686 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 1432212..1432559 Streptococcus pneumoniae AP200 9727537 YP_003877111.1 CDS SPAP_1523 NC_014494.1 1432838 1433674 R Operon 687 Gene 1 COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; amino acid ABC transporter/signal transduction system periplasmic domain-containing protein complement(1432838..1433674) Streptococcus pneumoniae AP200 9727538 YP_003877112.1 CDS SPAP_1524 NC_014494.1 1433687 1434316 R Operon 687 Gene 2 COG1126 ABC-type polar amino acid transport system, ATPase component; polar amino acid ABC transporter ATPase complement(1433687..1434316) Streptococcus pneumoniae AP200 9727539 YP_003877113.1 CDS SPAP_1525 NC_014494.1 1434326 1434967 R Operon 687 Gene 3 COG0765 ABC-type amino acid transport system, permease component; amino acid ABC transporter permease complement(1434326..1434967) Streptococcus pneumoniae AP200 9727540 YP_003877114.1 CDS SPAP_1526 NC_014494.1 1435113 1436342 R Operon 688 Gene 1 COG0457 FOG: TPR repeat; TPR repeat protein complement(1435113..1436342) Streptococcus pneumoniae AP200 9727541 YP_003877115.1 CDS SPAP_1527 NC_014494.1 1436332 1437498 R Operon 688 Gene 2 COG0628 Predicted permease; putative permease complement(1436332..1437498) Streptococcus pneumoniae AP200 9727542 YP_003877116.1 CDS SPAP_1528 NC_014494.1 1437642 1438655 D Operon 689 Gene 1 COG2706 3-carboxymuconate cyclase; 3-carboxymuconate cyclase 1437642..1438655 Streptococcus pneumoniae AP200 9727543 YP_003877117.1 CDS SPAP_1529 NC_014494.1 1438700 1439119 R Operon 690 Gene 1 COG0355 F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit); F0F1-type ATP synthase subunit epsilon complement(1438700..1439119) Streptococcus pneumoniae AP200 9727544 YP_003877118.1 CDS SPAP_1530 NC_014494.1 1439130 1440536 R Operon 690 Gene 2 COG0055 F0F1-type ATP synthase, beta subunit; F0F1-type ATP synthase subunit beta complement(1439130..1440536) Streptococcus pneumoniae AP200 9727545 YP_003877119.1 CDS SPAP_1531 NC_014494.1 1440622 1441500 R Operon 690 Gene 3 COG0224 F0F1-type ATP synthase, gamma subunit; F0F1-type ATP synthase subunit gamma complement(1440622..1441500) Streptococcus pneumoniae AP200 9727546 YP_003877120.1 CDS SPAP_1532 NC_014494.1 1441516 1443021 R Operon 690 Gene 4 COG0056 F0F1-type ATP synthase, alpha subunit; F0F1-type ATP synthase subunit alpha complement(1441516..1443021) Streptococcus pneumoniae AP200 9727547 YP_003877121.1 CDS SPAP_1533 NC_014494.1 1443036 1443572 R Operon 690 Gene 5 COG0712 F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein); F0F1-type ATP synthase subunit delta complement(1443036..1443572) Streptococcus pneumoniae AP200 9727548 YP_003877122.1 CDS SPAP_1534 NC_014494.1 1443572 1444066 R Operon 690 Gene 6 COG0711 F0F1-type ATP synthase, subunit b; F0F1-type ATP synthase subunit b complement(1443572..1444066) Streptococcus pneumoniae AP200 9727549 YP_003877123.1 CDS SPAP_1535 NC_014494.1 1444080 1444796 R Operon 690 Gene 7 COG0356 F0F1-type ATP synthase, subunit a; F0F1-type ATP synthase subunit a complement(1444080..1444796) Streptococcus pneumoniae AP200 9727550 YP_003877124.1 CDS SPAP_1536 NC_014494.1 1444831 1445031 R Operon 690 Gene 8 COG0636 F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K; F0F1-type ATP synthase subunit c/Archaeal/vacuolar-type H+-ATPase subunit K complement(1444831..1445031) Streptococcus pneumoniae AP200 9727551 YP_003877125.1 CDS SPAP_1537 NC_014494.1 1445106 1446116 R transposase-like protein, IS1239 complement(1445106..1446116) Streptococcus pneumoniae AP200 9727552 YP_003877126.1 CDS SPAP_1538 NC_014494.1 1446490 1446888 R Operon 691 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1446490..1446888) Streptococcus pneumoniae AP200 9727553 YP_003877127.1 CDS SPAP_1539 NC_014494.1 1447261 1447743 R Operon 692 Gene 1 COG0782 Transcription elongation factor; transcription elongation factor complement(1447261..1447743) Streptococcus pneumoniae AP200 9727554 YP_003877128.1 CDS SPAP_1540 NC_014494.1 1447814 1449469 R Operon 692 Gene 2 COG1559 Predicted periplasmic solute-binding protein; putative periplasmic solute-binding protein complement(1447814..1449469) Streptococcus pneumoniae AP200 9727555 YP_003877129.1 CDS SPAP_1541 NC_014494.1 1449550 1450044 R Operon 693 Gene 1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1449550..1450044) Streptococcus pneumoniae AP200 9727556 YP_003877130.1 CDS SPAP_1542 NC_014494.1 1450041 1450505 R Operon 693 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1450041..1450505) Streptococcus pneumoniae AP200 9727557 YP_003877131.1 CDS SPAP_1543 NC_014494.1 1450515 1451849 R Operon 693 Gene 3 COG0773 UDP-N-acetylmuramate-alanine ligase; UDP-N-acetylmuramate-alanine ligase complement(1450515..1451849) Streptococcus pneumoniae AP200 9727558 YP_003877132.1 CDS SPAP_1544 NC_014494.1 1451860 1452477 R Operon 693 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1451860..1452477) Streptococcus pneumoniae AP200 9727559 YP_003877133.1 CDS SPAP_1545 NC_014494.1 1452525 1455623 R Operon 693 Gene 5 COG0553 Superfamily II DNA/RNA helicases, SNF2 family; superfamily II DNA/RNA helicase complement(1452525..1455623) Streptococcus pneumoniae AP200 9727560 YP_003877134.1 CDS SPAP_1546 NC_014494.1 1455716 1456882 R Operon 694 Gene 1 COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities complement(1455716..1456882) Streptococcus pneumoniae AP200 9727561 YP_003877135.1 CDS SPAP_1547 NC_014494.1 1456890 1457984 R Operon 694 Gene 2 COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase/cystathionine gamma-synthase complement(1456890..1457984) Streptococcus pneumoniae AP200 9727562 YP_003877136.1 CDS SPAP_1548 NC_014494.1 1458142 1458864 R Operon 695 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1458142..1458864) Streptococcus pneumoniae AP200 9727563 YP_003877137.1 CDS SPAP_1549 NC_014494.1 1458889 1459824 R Operon 695 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1458889..1459824) Streptococcus pneumoniae AP200 9727564 YP_003877138.1 CDS SPAP_1550 NC_014494.1 1459979 1461955 R Operon 696 Gene 1 protein supported gi|148997067|ref|ZP_01824721.1| 30S ribosomal protein S1; hypothetical protein complement(1459979..1461955) Streptococcus pneumoniae AP200 9727565 YP_003877139.1 CDS SPAP_1551 NC_014494.1 1462159 1463781 R Operon 697 Gene 1 COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; O-antigen and teichoic acid exporter membrane protein complement(1462159..1463781) Streptococcus pneumoniae AP200 9727566 YP_003877140.1 CDS SPAP_1552 NC_014494.1 1463887 1465332 D Operon 698 Gene 1 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 1463887..1465332 Streptococcus pneumoniae AP200 9727567 YP_003877141.1 CDS SPAP_1553 NC_014494.1 1465375 1465572 R Operon 699 Gene 1 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1465375..1465572) Streptococcus pneumoniae AP200 9727568 YP_003877142.1 CDS SPAP_1554 NC_014494.1 1465673 1466269 R Operon 700 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1465673..1466269) Streptococcus pneumoniae AP200 9727569 YP_003877143.1 CDS SPAP_1555 NC_014494.1 1466306 1466818 R Operon 700 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1466306..1466818) Streptococcus pneumoniae AP200 9727570 YP_003877144.1 CDS SPAP_1556 NC_014494.1 1466904 1467839 R Operon 700 Gene 3 COG1227 Inorganic pyrophosphatase/exopolyphosphatase; inorganic pyrophosphatase/exopolyphosphatase complement(1466904..1467839) Streptococcus pneumoniae AP200 9727571 YP_003877145.1 CDS SPAP_1557 NC_014494.1 1467910 1468209 R Operon 700 Gene 4 COG2827 Predicted endonuclease containing a URI domain; putative endonuclease containing a URI domain complement(1467910..1468209) Streptococcus pneumoniae AP200 9727572 YP_003877146.1 CDS SPAP_1558 NC_014494.1 1468199 1468948 R Operon 700 Gene 5 COG4123 Predicted O-methyltransferase; putative O-methyltransferase complement(1468199..1468948) Streptococcus pneumoniae AP200 9727573 YP_003877147.1 CDS SPAP_1559 NC_014494.1 1469002 1469361 R Operon 700 Gene 6 protein supported gi|55820707|ref|YP_139149.1| hypothetical protein stu0628; hypothetical protein complement(1469002..1469361) Streptococcus pneumoniae AP200 9727574 YP_003877148.1 CDS SPAP_1560 NC_014494.1 1469363 1470763 R Operon 700 Gene 7 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(1469363..1470763) Streptococcus pneumoniae AP200 9727575 YP_003877149.1 CDS SPAP_1561 NC_014494.1 1471058 1471297 R Operon 701 Gene 1 protein supported gi|15901383|ref|NP_345987.1| 30S ribosomal protein S18; hypothetical protein complement(1471058..1471297) Streptococcus pneumoniae AP200 9727576 YP_003877150.1 CDS SPAP_1562 NC_014494.1 1471329 1471799 R Operon 701 Gene 2 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein complement(1471329..1471799) Streptococcus pneumoniae AP200 9727577 YP_003877151.1 CDS SPAP_1563 NC_014494.1 1471811 1472101 R Operon 701 Gene 3 protein supported gi|15901385|ref|NP_345989.1| 30S ribosomal protein S6; hypothetical protein complement(1471811..1472101) Streptococcus pneumoniae AP200 9727578 YP_003877152.1 CDS SPAP_1564 NC_014494.1 1472254 1473597 R Operon 702 Gene 1 COG0017 Aspartyl/asparaginyl-tRNA synthetases; aspartyl/asparaginyl-tRNA synthetase complement(1472254..1473597) Streptococcus pneumoniae AP200 9727579 YP_003877153.1 CDS SPAP_1565 NC_014494.1 1473616 1473981 R Operon 702 Gene 2 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase complement(1473616..1473981) Streptococcus pneumoniae AP200 9727580 YP_003877154.1 CDS SPAP_1566 NC_014494.1 1473974 1475161 R Operon 702 Gene 3 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase complement(1473974..1475161) Streptococcus pneumoniae AP200 9727581 YP_003877155.1 CDS SPAP_1567 NC_014494.1 1475158 1475646 R Operon 702 Gene 4 COG5353 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1475158..1475646) Streptococcus pneumoniae AP200 9727582 YP_003877156.1 CDS SPAP_1568 NC_014494.1 1475967 1476515 D Operon 703 Gene 1 COG0431 Predicted flavoprotein; putative flavoprotein 1475967..1476515 Streptococcus pneumoniae AP200 9727583 YP_003877157.1 CDS SPAP_1569 NC_014494.1 1476793 1477521 R Operon 704 Gene 1 COG3022 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1476793..1477521) Streptococcus pneumoniae AP200 9727584 YP_003877158.1 CDS SPAP_1570 NC_014494.1 1477600 1477779 R Operon 704 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1477600..1477779) Streptococcus pneumoniae AP200 9727585 YP_003877159.1 CDS SPAP_1571 NC_014494.1 1477931 1479526 R Operon 705 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1477931..1479526) Streptococcus pneumoniae AP200 9727586 YP_003877160.1 CDS SPAP_1572 NC_014494.1 1479538 1479948 R Operon 705 Gene 2 COG0242 N-formylmethionyl-tRNA deformylase; N-formylmethionyl-tRNA deformylase complement(1479538..1479948) Streptococcus pneumoniae AP200 9727587 YP_003877161.1 CDS SPAP_1573 NC_014494.1 1480064 1480855 R Operon 706 Gene 1 COG0625 Glutathione S-transferase; glutathione S-transferase complement(1480064..1480855) Streptococcus pneumoniae AP200 9727588 YP_003877162.1 CDS SPAP_1574 NC_014494.1 1480868 1483564 R Operon 706 Gene 2 COG0474 Cation transport ATPase; cation transport ATPase complement(1480868..1483564) Streptococcus pneumoniae AP200 9727589 YP_003877163.1 CDS SPAP_1575 NC_014494.1 1483868 1485052 D Operon 707 Gene 1 COG0053 Predicted Co/Zn/Cd cation transporters; putative Co/Zn/Cd cation transporter 1483868..1485052 Streptococcus pneumoniae AP200 9727590 YP_003877164.1 CDS SPAP_1576 NC_014494.1 1485195 1487066 R Operon 708 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase complement(1485195..1487066) Streptococcus pneumoniae AP200 9727591 YP_003877165.1 CDS SPAP_1577 NC_014494.1 1487063 1488262 R Operon 708 Gene 2 COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; tRNA nucleotidyltransferase/poly(A) polymerase complement(1487063..1488262) Streptococcus pneumoniae AP200 9727592 YP_003877166.1 CDS SPAP_1578 NC_014494.1 1488259 1489026 R Operon 708 Gene 3 COG0289 Dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(1488259..1489026) Streptococcus pneumoniae AP200 9727593 YP_003877167.1 CDS SPAP_1579 NC_014494.1 1489292 1490140 R Operon 709 Gene 1 COG1307 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1489292..1490140) Streptococcus pneumoniae AP200 9727594 YP_003877168.1 CDS SPAP_1580 NC_014494.1 1490142 1490528 R Operon 709 Gene 2 COG4835 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1490142..1490528) Streptococcus pneumoniae AP200 9727595 YP_003877169.1 CDS SPAP_1581 NC_014494.1 1490590 1491942 R Operon 709 Gene 3 COG1109 Phosphomannomutase; phosphomannomutase complement(1490590..1491942) Streptococcus pneumoniae AP200 9727596 YP_003877170.1 CDS SPAP_1582 NC_014494.1 1491966 1492745 R Operon 709 Gene 4 COG4856 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1491966..1492745) Streptococcus pneumoniae AP200 9727597 YP_003877171.1 CDS SPAP_1583 NC_014494.1 1492732 1493589 R Operon 709 Gene 5 COG1624 Uncharacterized conserved protein; hypothetical protein complement(1492732..1493589) Streptococcus pneumoniae AP200 9727598 YP_003877172.1 CDS SPAP_1584 NC_014494.1 1493725 1494690 D Operon 710 Gene 1 COG0492 Thioredoxin reductase; thioredoxin reductase 1493725..1494690 Streptococcus pneumoniae AP200 9727599 YP_003877173.1 CDS SPAP_1585 NC_014494.1 1494724 1495635 R Operon 711 Gene 1 COG1481 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1494724..1495635) Streptococcus pneumoniae AP200 9727600 YP_003877174.1 CDS SPAP_1586 NC_014494.1 1495632 1496609 R Operon 711 Gene 2 COG0391 Uncharacterized conserved protein; hypothetical protein complement(1495632..1496609) Streptococcus pneumoniae AP200 9727601 YP_003877175.1 CDS SPAP_1587 NC_014494.1 1496606 1497496 R Operon 711 Gene 3 COG1660 Predicted P-loop-containing kinase; putative P-loop-containing kinase complement(1496606..1497496) Streptococcus pneumoniae AP200 9727602 YP_003877176.1 CDS SPAP_1588 NC_014494.1 1497548 1497928 R Operon 712 Gene 1 COG0251 Putative translation initiation inhibitor, yjgF family; putative translation initiation inhibitor complement(1497548..1497928) Streptococcus pneumoniae AP200 9727603 YP_003877177.1 CDS SPAP_1589 NC_014494.1 1497939 1498526 R Operon 712 Gene 2 COG0218 Predicted GTPase; putative GTPase complement(1497939..1498526) Streptococcus pneumoniae AP200 9727604 YP_003877178.1 CDS SPAP_1590 NC_014494.1 1498535 1499767 R Operon 712 Gene 3 COG1219 ATP-dependent protease Clp, ATPase subunit; ATP-dependent protease Clp, ATPase subunit complement(1498535..1499767) Streptococcus pneumoniae AP200 9727605 YP_003877179.1 CDS SPAP_1591 NC_014494.1 1499799 1499969 R Operon 712 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1499799..1499969) Streptococcus pneumoniae AP200 9727606 YP_003877180.1 CDS SPAP_1592 NC_014494.1 1499969 1500475 R Operon 712 Gene 5 COG0262 Dihydrofolate reductase; dihydrofolate reductase complement(1499969..1500475) Streptococcus pneumoniae AP200 9727607 YP_003877181.1 CDS SPAP_1593 NC_014494.1 1500605 1501123 R Operon 713 Gene 1 COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); DNA-binding ferritin-like protein complement(1500605..1501123) Streptococcus pneumoniae AP200 9727608 YP_003877182.1 CDS SPAP_1594 NC_014494.1 1501619 1503091 R Operon 714 Gene 1 COG5263 FOG: Glucan-binding domain (YG repeat); glucan-binding domain-containing protein complement(1501619..1503091) Streptococcus pneumoniae AP200 9727609 YP_003877183.1 CDS SPAP_1595 NC_014494.1 1503162 1503920 R Operon 714 Gene 2 COG0149 Triosephosphate isomerase; triosephosphate isomerase complement(1503162..1503920) Streptococcus pneumoniae AP200 9727610 YP_003877184.1 CDS SPAP_1596 NC_014494.1 1504018 1504695 R Operon 715 Gene 1 COG3935 Putative primosome component and related proteins; putative primosome component-like protein complement(1504018..1504695) Streptococcus pneumoniae AP200 9727611 YP_003877185.1 CDS SPAP_1597 NC_014494.1 1504704 1505648 R Operon 715 Gene 2 COG1897 Homoserine trans-succinylase; homoserine trans-succinylase complement(1504704..1505648) Streptococcus pneumoniae AP200 9727612 YP_003877186.1 CDS SPAP_1598 NC_014494.1 1505688 1505843 D Operon 716 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1505688..1505843 Streptococcus pneumoniae AP200 9727613 YP_003877187.1 CDS SPAP_1599 NC_014494.1 1505830 1506342 R Operon 717 Gene 1 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein complement(1505830..1506342) Streptococcus pneumoniae AP200 9727614 YP_003877188.1 CDS SPAP_1600 NC_014494.1 1506429 1507187 R Operon 717 Gene 2 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase complement(1506429..1507187) Streptococcus pneumoniae AP200 9727615 YP_003877189.1 CDS SPAP_1601 NC_014494.1 1507688 1508818 R Operon 718 Gene 1 COG3839 ABC-type sugar transport systems, ATPase components; sugar ABC transporter ATPase complement(1507688..1508818) Streptococcus pneumoniae AP200 9727616 YP_003877190.1 CDS SPAP_1604 NC_014494.1 1509268 1509843 R Operon 719 Gene 2 COG1335 Amidases related to nicotinamidase; amidase complement(1509268..1509843) Streptococcus pneumoniae AP200 9727618 YP_003877191.1 CDS SPAP_1605 NC_014494.1 1509843 1510631 R Operon 719 Gene 3 COG4465 Pleiotropic transcriptional repressor; pleiotropic transcriptional repressor complement(1509843..1510631) Streptococcus pneumoniae AP200 9727619 YP_003877192.1 CDS SPAP_1606 NC_014494.1 1510750 1511703 R transposase-like protein, IS1239 complement(1510750..1511703) Streptococcus pneumoniae AP200 9727620 YP_003877193.1 CDS SPAP_1607 NC_014494.1 1512140 1513714 R Operon 721 Gene 1 COG0513 Superfamily II DNA and RNA helicases; superfamily II DNA and RNA helicase complement(1512140..1513714) Streptococcus pneumoniae AP200 9727621 YP_003877194.1 CDS SPAP_1608 NC_014494.1 1513913 1515139 R Operon 722 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(1513913..1515139) Streptococcus pneumoniae AP200 9727622 YP_003877195.1 CDS SPAP_1609 NC_014494.1 1515333 1516649 D Operon 723 Gene 1 COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes; pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component-like protein 1515333..1516649 Streptococcus pneumoniae AP200 9727623 YP_003877196.1 CDS SPAP_1610 NC_014494.1 1516748 1518091 D Operon 723 Gene 2 COG0769 UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramyl tripeptide synthase 1516748..1518091 Streptococcus pneumoniae AP200 9727624 YP_003877197.1 CDS SPAP_1611 NC_014494.1 1518091 1518873 D Operon 723 Gene 3 COG3442 Predicted glutamine amidotransferase; putative glutamine amidotransferase 1518091..1518873 Streptococcus pneumoniae AP200 9727625 YP_003877198.1 CDS SPAP_1612 NC_014494.1 1518999 1520081 D Operon 724 Gene 1 COG0006 Xaa-Pro aminopeptidase; Xaa-Pro aminopeptidase 1518999..1520081 Streptococcus pneumoniae AP200 9727626 YP_003877199.1 CDS SPAP_1613 NC_014494.1 1520029 1520277 D Operon 724 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase 1520029..1520277 Streptococcus pneumoniae AP200 9727627 YP_003877200.1 CDS SPAP_1614 NC_014494.1 1520494 1521228 R Operon 725 Gene 1 COG2801 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 complement(1520494..1521228) Streptococcus pneumoniae AP200 9727628 YP_003877201.1 CDS SPAP_1615 NC_014494.1 1521228 1521395 R Operon 725 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1521228..1521395) Streptococcus pneumoniae AP200 9727629 YP_003877202.1 CDS SPAP_1616 NC_014494.1 1521558 1521803 R Operon 726 Gene 1 COG2963 Transposase and inactivated derivatives; transposase-like protein, ISSpn1 ISSpn3 complement(1521558..1521803) Streptococcus pneumoniae AP200 9727630 YP_003877203.1 CDS SPAP_1617 NC_014494.1 1521968 1522429 R Operon 727 Gene 1 COG4720 Predicted membrane protein; hypothetical protein complement(1521968..1522429) Streptococcus pneumoniae AP200 9727631 YP_003877204.1 CDS SPAP_1618 NC_014494.1 1522407 1523180 R Operon 727 Gene 2 COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; hydroxymethylpyrimidine/phosphomethylpyrimidine kinase complement(1522407..1523180) Streptococcus pneumoniae AP200 9727632 YP_003877205.1 CDS SPAP_1619 NC_014494.1 1523170 1523919 R Operon 727 Gene 3 COG0101 Pseudouridylate synthase; pseudouridylate synthase complement(1523170..1523919) Streptococcus pneumoniae AP200 9727633 YP_003877206.1 CDS SPAP_1620 NC_014494.1 1524099 1524260 D Operon 728 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1524099..1524260 Streptococcus pneumoniae AP200 9727634 YP_003877207.1 CDS SPAP_1621 NC_014494.1 1524232 1525383 R Operon 729 Gene 1 COG0477 Permeases of the major facilitator superfamily; major facilitator superfamily permease complement(1524232..1525383) Streptococcus pneumoniae AP200 9727635 YP_003877208.1 CDS SPAP_1622 NC_014494.1 1525623 1526252 R Operon 730 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1525623..1526252) Streptococcus pneumoniae AP200 9727636 YP_003877209.1 CDS SPAP_1623 NC_014494.1 1526255 1526593 R Operon 730 Gene 2 COG2824 Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism; hypothetical protein complement(1526255..1526593) Streptococcus pneumoniae AP200 9727637 YP_003877210.1 CDS SPAP_1624 NC_014494.1 1526724 1527395 R Operon 731 Gene 1 COG0283 Cytidylate kinase; cytidylate kinase complement(1526724..1527395) Streptococcus pneumoniae AP200 9727638 YP_003877211.1 CDS SPAP_1625 NC_014494.1 1527404 1527880 R Operon 731 Gene 2 protein supported gi|148997664|ref|ZP_01825228.1| hypothetical protein CGSSp11BS70_02114; hypothetical protein complement(1527404..1527880) Streptococcus pneumoniae AP200 9727639 YP_003877212.1 CDS SPAP_1626 NC_014494.1 1527925 1528137 D Operon 732 Gene 1 COG1141 Ferredoxin; ferredoxin 1527925..1528137 Streptococcus pneumoniae AP200 9727640 YP_003877213.1 CDS SPAP_1627 NC_014494.1 1528188 1529150 R Operon 733 Gene 1 COG0463 Glycosyltransferases involved in cell wall biogenesis; glycosyltransferase complement(1528188..1529150) Streptococcus pneumoniae AP200 9727641 YP_003877214.1 CDS SPAP_1628 NC_014494.1 1529155 1530174 R Operon 733 Gene 2 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(1529155..1530174) Streptococcus pneumoniae AP200 9727642 YP_003877215.1 CDS SPAP_1629 NC_014494.1 1530430 1531533 R Operon 734 Gene 1 COG0665 Glycine/D-amino acid oxidases (deaminating); glycine/D-amino acid oxidase complement(1530430..1531533) Streptococcus pneumoniae AP200 9727643 YP_003877216.1 CDS SPAP_1630 NC_014494.1 1531550 1532347 R Operon 734 Gene 2 COG0327 Uncharacterized conserved protein; hypothetical protein complement(1531550..1532347) Streptococcus pneumoniae AP200 9727644 YP_003877217.1 CDS SPAP_1631 NC_014494.1 1532444 1533013 R Operon 734 Gene 3 COG2384 Predicted SAM-dependent methyltransferase; putative SAM-dependent methyltransferase complement(1532444..1533013) Streptococcus pneumoniae AP200 9727645 YP_003877218.1 CDS SPAP_1632 NC_014494.1 1533115 1535451 R Operon 735 Gene 1 COG0474 Cation transport ATPase; cation transport ATPase complement(1533115..1535451) Streptococcus pneumoniae AP200 9727646 YP_003877219.1 CDS SPAP_1633 NC_014494.1 1535584 1536333 D Operon 736 Gene 1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1535584..1536333 Streptococcus pneumoniae AP200 9727647 YP_003877220.1 CDS SPAP_1634 NC_014494.1 1536626 1537240 R Operon 737 Gene 1 COG4300 Predicted permease, cadmium resistance protein; putative cadmium resistance permease complement(1536626..1537240) Streptococcus pneumoniae AP200 9727648 YP_003877221.1 CDS SPAP_1635 NC_014494.1 1538055 1538324 R Operon 738 Gene 1 protein supported gi|15901462|ref|NP_346066.1| 30S ribosomal protein S15; 30S ribosomal protein S15 complement(1538055..1538324) Streptococcus pneumoniae AP200 9727649 YP_003877222.1 CDS SPAP_1636 NC_014494.1 1538465 1539094 R Operon 739 Gene 1 COG2910 Putative NADH-flavin reductase; putative NADH-flavin reductase complement(1538465..1539094) Streptococcus pneumoniae AP200 9727650 YP_003877223.1 CDS SPAP_1637 NC_014494.1 1539331 1539495 D Operon 740 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1539331..1539495 Streptococcus pneumoniae AP200 9727651 YP_003877224.1 CDS SPAP_1638 NC_014494.1 1539951 1540172 D Operon 741 Gene 1 protein supported gi|148997678|ref|ZP_01825242.1| 30S ribosomal protein S15; hypothetical protein 1539951..1540172 Streptococcus pneumoniae AP200 9727652 YP_003877225.1 CDS SPAP_1639 NC_014494.1 1540332 1542275 D Operon 741 Gene 2 COG0441 Threonyl-tRNA synthetase; threonyl-tRNA synthetase 1540332..1542275 Streptococcus pneumoniae AP200 9727653 YP_003877226.1 CDS SPAP_1640 NC_014494.1 1542324 1543109 R Operon 742 Gene 1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase complement(1542324..1543109) Streptococcus pneumoniae AP200 9727654 YP_003877227.1 CDS SPAP_1641 NC_014494.1 1543291 1543968 R Operon 742 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator complement(1543291..1543968) Streptococcus pneumoniae AP200 9727655 YP_003877228.1 CDS SPAP_1642 NC_014494.1 1544124 1545197 D Operon 743 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1544124..1545197 Streptococcus pneumoniae AP200 9727656 YP_003877229.1 CDS SPAP_1643 NC_014494.1 1545288 1545590 R Operon 744 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1545288..1545590) Streptococcus pneumoniae AP200 9727657 YP_003877230.1 CDS SPAP_1644 NC_014494.1 1545659 1546096 R Operon 744 Gene 2 COG1959 Predicted transcriptional regulator; putative transcriptional regulator complement(1545659..1546096) Streptococcus pneumoniae AP200 9727658 YP_003877231.1 CDS SPAP_1645 NC_014494.1 1546172 1547014 R Operon 744 Gene 3 COG0639 Diadenosine tetraphosphatase and related serine/threonine protein phosphatases; diadenosine tetraphosphatase-like serine/threonine protein phosphatase complement(1546172..1547014) Streptococcus pneumoniae AP200 9727659 YP_003877232.1 CDS SPAP_1646 NC_014494.1 1547126 1547776 D Operon 745 Gene 1 COG1321 Mn-dependent transcriptional regulator; Mn-dependent transcriptional regulator 1547126..1547776 Streptococcus pneumoniae AP200 9727660 YP_003877233.1 CDS SPAP_1647 NC_014494.1 1547894 1548601 D Operon 746 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1547894..1548601 Streptococcus pneumoniae AP200 9727661 YP_003877234.1 CDS SPAP_1648 NC_014494.1 1548732 1549145 D Operon 747 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1548732..1549145 Streptococcus pneumoniae AP200 9727662 YP_003877235.1 CDS SPAP_1649 NC_014494.1 1549128 1549298 R Operon 748 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1549128..1549298) Streptococcus pneumoniae AP200 9727663 YP_003877236.1 CDS SPAP_1650 NC_014494.1 1549416 1549577 D Operon 749 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1549416..1549577 Streptococcus pneumoniae AP200 9727664 YP_003877237.1 CDS SPAP_1651 NC_014494.1 1549616 1550059 R Operon 750 Gene 1 COG1490 D-Tyr-tRNAtyr deacylase; D-Tyr-tRNAtyr deacylase complement(1549616..1550059) Streptococcus pneumoniae AP200 9727665 YP_003877238.1 CDS SPAP_1652 NC_014494.1 1550089 1552311 R Operon 750 Gene 2 COG0317 Guanosine polyphosphate pyrophosphohydrolases/synthetases; guanosine polyphosphate pyrophosphohydrolase/synthetase complement(1550089..1552311) Streptococcus pneumoniae AP200 9727666 YP_003877239.1 CDS SPAP_1653 NC_014494.1 1552807 1552965 D Operon 751 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1552807..1552965 Streptococcus pneumoniae AP200 9727667 YP_003877240.1 CDS SPAP_1654 NC_014494.1 1553305 1553934 D Operon 752 Gene 1 COG0491 Zn-dependent hydrolases, including glyoxylases; Zn-dependent hydrolase, including glyoxylases 1553305..1553934 Streptococcus pneumoniae AP200 9727668 YP_003877241.1 CDS SPAP_1655 NC_014494.1 1554056 1555948 R Operon 753 Gene 1 COG3590 Predicted metalloendopeptidase; putative metalloendopeptidase complement(1554056..1555948) Streptococcus pneumoniae AP200 9727669 YP_003877242.1 CDS SPAP_1656 NC_014494.1 1556239 1556961 D Operon 754 Gene 1 COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn/Zn ABC transporter ATPase 1556239..1556961 Streptococcus pneumoniae AP200 9727670 YP_003877243.1 CDS SPAP_1657 NC_014494.1 1556958 1557806 D Operon 754 Gene 2 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease 1556958..1557806 Streptococcus pneumoniae AP200 9727671 YP_003877244.1 CDS SPAP_1658 NC_014494.1 1557838 1558767 D Operon 754 Gene 3 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin 1557838..1558767 Streptococcus pneumoniae AP200 9727672 YP_003877245.1 CDS SPAP_1659 NC_014494.1 1558890 1559381 D Operon 755 Gene 1 COG2077 Peroxiredoxin; peroxiredoxin 1558890..1559381 Streptococcus pneumoniae AP200 9727673 YP_003877246.1 CDS SPAP_1660 NC_014494.1 1559477 1562185 R Operon 756 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease complement(1559477..1562185) Streptococcus pneumoniae AP200 9727674 YP_003877247.1 CDS SPAP_1661 NC_014494.1 1562187 1562888 R Operon 756 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase complement(1562187..1562888) Streptococcus pneumoniae AP200 9727675 YP_003877248.1 CDS SPAP_1662 NC_014494.1 1563160 1565550 R Operon 757 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1563160..1565550) Streptococcus pneumoniae AP200 9727676 YP_003877249.1 CDS SPAP_1663 NC_014494.1 1565603 1566295 R Operon 757 Gene 2 COG0588 Phosphoglycerate mutase 1; phosphoglycerate mutase complement(1565603..1566295) Streptococcus pneumoniae AP200 9727677 YP_003877250.1 CDS SPAP_1664 NC_014494.1 1566910 1567170 R Operon 758 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1566910..1567170) Streptococcus pneumoniae AP200 9727678 YP_003877251.1 CDS SPAP_1665 NC_014494.1 1567618 1570410 R Operon 759 Gene 1 COG0060 Isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase complement(1567618..1570410) Streptococcus pneumoniae AP200 9727679 YP_003877252.1 CDS SPAP_1666 NC_014494.1 1570758 1571546 R Operon 760 Gene 1 COG3599 Cell division initiation protein; cell division initiation protein complement(1570758..1571546) Streptococcus pneumoniae AP200 9727680 YP_003877253.1 CDS SPAP_1667 NC_014494.1 1571555 1572340 R Operon 760 Gene 2 protein supported gi|15901497|ref|NP_346101.1| ylmH protein; hypothetical protein complement(1571555..1572340) Streptococcus pneumoniae AP200 9727681 YP_003877254.1 CDS SPAP_1668 NC_014494.1 1572337 1572600 R Operon 760 Gene 3 COG0762 Predicted integral membrane protein; putative integral membrane protein complement(1572337..1572600) Streptococcus pneumoniae AP200 9727682 YP_003877255.1 CDS SPAP_1669 NC_014494.1 1572600 1573139 R Operon 760 Gene 4 COG1799 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1572600..1573139) Streptococcus pneumoniae AP200 9727683 YP_003877256.1 CDS SPAP_1670 NC_014494.1 1573149 1573820 R Operon 760 Gene 5 COG0325 Predicted enzyme with a TIM-barrel fold; hypothetical protein complement(1573149..1573820) Streptococcus pneumoniae AP200 9727684 YP_003877257.1 CDS SPAP_1671 NC_014494.1 1573825 1575084 R Operon 760 Gene 6 COG0206 Cell division GTPase; cell division GTPase complement(1573825..1575084) Streptococcus pneumoniae AP200 9727685 YP_003877258.1 CDS SPAP_1672 NC_014494.1 1575101 1576474 R Operon 760 Gene 7 COG0849 Actin-like ATPase involved in cell division; actin-like ATPase complement(1575101..1576474) Streptococcus pneumoniae AP200 9727686 YP_003877259.1 CDS SPAP_1673 NC_014494.1 1576693 1577397 R Operon 761 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1576693..1577397) Streptococcus pneumoniae AP200 9727687 YP_003877260.1 CDS SPAP_1674 NC_014494.1 1577488 1578099 R Operon 761 Gene 2 COG1051 ADP-ribose pyrophosphatase; ADP-ribose pyrophosphatase complement(1577488..1578099) Streptococcus pneumoniae AP200 9727688 YP_003877261.1 CDS SPAP_1675 NC_014494.1 1578086 1579459 R Operon 761 Gene 3 COG0770 UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramyl pentapeptide synthase complement(1578086..1579459) Streptococcus pneumoniae AP200 9727689 YP_003877262.1 CDS SPAP_1676 NC_014494.1 1579543 1580586 R Operon 761 Gene 4 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; D-alanine-D-alanine ligase-like ATP-grasp enzyme complement(1579543..1580586) Streptococcus pneumoniae AP200 9727690 YP_003877263.1 CDS SPAP_1677 NC_014494.1 1580762 1581358 R Operon 762 Gene 1 COG0353 Recombinational DNA repair protein (RecF pathway); recombinational DNA repair ATPase complement(1580762..1581358) Streptococcus pneumoniae AP200 9727691 YP_003877264.1 CDS SPAP_1678 NC_014494.1 1581369 1583411 R Operon 762 Gene 2 COG0768 Cell division protein FtsI/penicillin-binding protein 2; cell division protein FtsI complement(1581369..1583411) Streptococcus pneumoniae AP200 9727692 YP_003877265.1 CDS SPAP_1679 NC_014494.1 1583626 1584477 D Operon 763 Gene 1 COG1737 Transcriptional regulators; transcriptional regulator 1583626..1584477 Streptococcus pneumoniae AP200 9727693 YP_003877266.1 CDS SPAP_1680 NC_014494.1 1584493 1585377 R Operon 764 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase complement(1584493..1585377) Streptococcus pneumoniae AP200 9727694 YP_003877267.1 CDS SPAP_1681 NC_014494.1 1585395 1586312 R Operon 764 Gene 2 COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; dihydrodipicolinate synthase/N-acetylneuraminate lyase complement(1585395..1586312) Streptococcus pneumoniae AP200 9727695 YP_003877268.1 CDS SPAP_1682 NC_014494.1 1586481 1587125 R Operon 765 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1586481..1587125) Streptococcus pneumoniae AP200 9727696 YP_003877269.1 CDS SPAP_1683 NC_014494.1 1587208 1587402 R Operon 765 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1587208..1587402) Streptococcus pneumoniae AP200 9727697 YP_003877270.1 CDS SPAP_1684 NC_014494.1 1587412 1587756 R Operon 765 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1587412..1587756) Streptococcus pneumoniae AP200 9727698 YP_003877271.1 CDS SPAP_1685 NC_014494.1 1587853 1588305 R Operon 765 Gene 4 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta complement(1587853..1588305) Streptococcus pneumoniae AP200 9727699 YP_003877272.1 CDS SPAP_1686 NC_014494.1 1588578 1589417 R Operon 766 Gene 1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease complement(1588578..1589417) Streptococcus pneumoniae AP200 9727700 YP_003877273.1 CDS SPAP_1687 NC_014494.1 1589433 1590320 R Operon 766 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease complement(1589433..1590320) Streptococcus pneumoniae AP200 9727701 YP_003877274.1 CDS SPAP_1688 NC_014494.1 1590551 1591879 R Operon 766 Gene 3 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein complement(1590551..1591879) Streptococcus pneumoniae AP200 9727702 YP_003877275.1 CDS SPAP_1689 NC_014494.1 1592004 1593521 R Operon 767 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC complement(1592004..1593521) Streptococcus pneumoniae AP200 9727703 YP_003877276.1 CDS SPAP_1690 NC_014494.1 1593540 1594238 R Operon 767 Gene 2 COG3010 Putative N-acetylmannosamine-6-phosphate epimerase; putative N-acetylmannosamine-6-phosphate epimerase complement(1593540..1594238) Streptococcus pneumoniae AP200 9727704 YP_003877277.1 CDS SPAP_1691 NC_014494.1 1594412 1595515 R Operon 768 Gene 1 COG0673 Predicted dehydrogenases and related proteins; putative dehydrogenases-like protein complement(1594412..1595515) Streptococcus pneumoniae AP200 9727705 YP_003877278.1 CDS SPAP_1692 NC_014494.1 1595527 1597146 R neuraminidase NanB complement(1595527..1597146) Streptococcus pneumoniae AP200 9727706 YP_003877279.1 CDS SPAP_1693 NC_014494.1 1597188 1597613 D transposase-like protein, IS1515 1597188..1597613 Streptococcus pneumoniae AP200 9727707 YP_003877280.1 CDS SPAP_1694 NC_014494.1 1597659 1598003 D transposase-like protein, IS1515 1597659..1598003 Streptococcus pneumoniae AP200 9727708 YP_003877281.1 CDS SPAP_1695 NC_014494.1 1598000 1598494 R neuraminidase NanB complement(1598000..1598494) Streptococcus pneumoniae AP200 9727709 YP_003877282.1 CDS SPAP_1696 NC_014494.1 1598512 1599345 R Operon 770 Gene 2 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease complement(1598512..1599345) Streptococcus pneumoniae AP200 9727710 YP_003877283.1 CDS SPAP_1697 NC_014494.1 1599345 1600229 R Operon 770 Gene 3 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease complement(1599345..1600229) Streptococcus pneumoniae AP200 9727711 YP_003877284.1 CDS SPAP_1698 NC_014494.1 1600308 1601645 R Operon 770 Gene 4 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein complement(1600308..1601645) Streptococcus pneumoniae AP200 9727712 YP_003877285.1 CDS SPAP_1699 NC_014494.1 1601664 1602116 R Operon 770 Gene 5 COG2731 Beta-galactosidase, beta subunit; beta-galactosidase subunit beta complement(1601664..1602116) Streptococcus pneumoniae AP200 9727713 YP_003877286.1 CDS SPAP_1700 NC_014494.1 1603130 1606027 R Operon 771 Gene 1 COG4409 Neuraminidase (sialidase); neuraminidase complement(1603130..1606027) Streptococcus pneumoniae AP200 9727714 YP_003877287.1 CDS SPAP_1701 NC_014494.1 1606315 1606542 R Operon 771 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1606315..1606542) Streptococcus pneumoniae AP200 9727715 YP_003877288.1 CDS SPAP_1702 NC_014494.1 1606940 1607443 D Operon 772 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1606940..1607443 Streptococcus pneumoniae AP200 9727716 YP_003877289.1 CDS SPAP_1703 NC_014494.1 1607797 1608777 R Operon 773 Gene 1 COG3458 Acetyl esterase (deacetylase); acetyl esterase complement(1607797..1608777) Streptococcus pneumoniae AP200 9727717 YP_003877290.1 CDS SPAP_1704 NC_014494.1 1609093 1611108 R Operon 774 Gene 1 COG1200 RecG-like helicase; RecG-like helicase complement(1609093..1611108) Streptococcus pneumoniae AP200 9727718 YP_003877291.1 CDS SPAP_1705 NC_014494.1 1611127 1612230 R Operon 774 Gene 2 COG0787 Alanine racemase; alanine racemase complement(1611127..1612230) Streptococcus pneumoniae AP200 9727719 YP_003877292.1 CDS SPAP_1706 NC_014494.1 1612220 1612588 R Operon 774 Gene 3 COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); phosphopantetheinyl transferase complement(1612220..1612588) Streptococcus pneumoniae AP200 9727720 YP_003877293.1 CDS SPAP_1707 NC_014494.1 1612627 1613658 R Operon 774 Gene 4 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase complement(1612627..1613658) Streptococcus pneumoniae AP200 9727721 YP_003877294.1 CDS SPAP_1708 NC_014494.1 1613660 1614691 R Operon 774 Gene 5 COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase complement(1613660..1614691) Streptococcus pneumoniae AP200 9727722 YP_003877295.1 CDS SPAP_1709 NC_014494.1 1614772 1617285 R Operon 774 Gene 6 COG0653 Preprotein translocase subunit SecA (ATPase, RNA helicase); preprotein translocase subunit SecA complement(1614772..1617285) Streptococcus pneumoniae AP200 9727723 YP_003877296.1 CDS SPAP_1710 NC_014494.1 1617746 1618378 R Operon 775 Gene 1 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase complement(1617746..1618378) Streptococcus pneumoniae AP200 9727724 YP_003877297.1 CDS SPAP_1711 NC_014494.1 1618382 1618957 R Operon 775 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1618382..1618957) Streptococcus pneumoniae AP200 9727725 YP_003877298.1 CDS SPAP_1712 NC_014494.1 1619016 1619807 R Operon 775 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1619016..1619807) Streptococcus pneumoniae AP200 9727726 YP_003877299.1 CDS SPAP_1713 NC_014494.1 1619992 1620327 R Operon 776 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1619992..1620327) Streptococcus pneumoniae AP200 9727727 YP_003877300.1 CDS SPAP_1714 NC_014494.1 1620893 1622203 R Operon 777 Gene 1 COG1160 Predicted GTPases; putative GTPase complement(1620893..1622203) Streptococcus pneumoniae AP200 9727728 YP_003877301.1 CDS SPAP_1715 NC_014494.1 1622217 1622930 R Operon 777 Gene 2 COG0778 Nitroreductase; nitroreductase complement(1622217..1622930) Streptococcus pneumoniae AP200 9727729 YP_003877302.1 CDS SPAP_1716 NC_014494.1 1622927 1623823 R Operon 777 Gene 3 COG1484 DNA replication protein; DNA replication protein complement(1622927..1623823) Streptococcus pneumoniae AP200 9727730 YP_003877303.1 CDS SPAP_1717 NC_014494.1 1623824 1624993 R Operon 777 Gene 4 COG3611 Replication initiation/membrane attachment protein; Replication initiation/membrane attachment protein complement(1623824..1624993) Streptococcus pneumoniae AP200 9727731 YP_003877304.1 CDS SPAP_1718 NC_014494.1 1624994 1625467 R Operon 777 Gene 5 COG1327 Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains; putative transcriptional regulator complement(1624994..1625467) Streptococcus pneumoniae AP200 9727732 YP_003877305.1 CDS SPAP_1719 NC_014494.1 1625607 1625972 D Operon 778 Gene 1 COG1725 Predicted transcriptional regulators; putative transcriptional regulator 1625607..1625972 Streptococcus pneumoniae AP200 9727733 YP_003877306.1 CDS SPAP_1720 NC_014494.1 1625977 1626672 D Operon 778 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase 1625977..1626672 Streptococcus pneumoniae AP200 9727734 YP_003877307.1 CDS SPAP_1721 NC_014494.1 1626689 1627456 D Operon 778 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1626689..1627456 Streptococcus pneumoniae AP200 9727735 YP_003877308.1 CDS SPAP_1722 NC_014494.1 1627809 1629008 R Operon 779 Gene 1 COG1668 ABC-type Na+ efflux pump, permease component; Na+ efflux pump ABC transporter permease complement(1627809..1629008) Streptococcus pneumoniae AP200 9727736 YP_003877309.1 CDS SPAP_1723 NC_014494.1 1629005 1629898 R Operon 779 Gene 2 COG4152 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase complement(1629005..1629898) Streptococcus pneumoniae AP200 9727737 YP_003877310.1 CDS SPAP_1724 NC_014494.1 1630590 1630793 D transposase-like protein, IS1239 1630590..1630793 Streptococcus pneumoniae AP200 9727738 YP_003877311.1 CDS SPAP_1725 NC_014494.1 1631208 1631825 D Operon 781 Gene 1 COG0398 Uncharacterized conserved protein; hypothetical protein 1631208..1631825 Streptococcus pneumoniae AP200 9727739 YP_003877312.1 CDS SPAP_1726 NC_014494.1 1632145 1633032 R Operon 782 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase complement(1632145..1633032) Streptococcus pneumoniae AP200 9727740 YP_003877313.1 CDS SPAP_1727 NC_014494.1 1633181 1635118 R Operon 783 Gene 1 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC complement(1633181..1635118) Streptococcus pneumoniae AP200 9727741 YP_003877314.1 CDS SPAP_1728 NC_014494.1 1635244 1635441 R Operon 784 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1635244..1635441) Streptococcus pneumoniae AP200 9727742 YP_003877315.1 CDS SPAP_1729 NC_014494.1 1635494 1636948 D Operon 785 Gene 1 COG1621 Beta-fructosidases (levanase/invertase); levanase/invertase 1635494..1636948 Streptococcus pneumoniae AP200 9727743 YP_003877316.1 CDS SPAP_1730 NC_014494.1 1636929 1637894 D Operon 785 Gene 2 COG1609 Transcriptional regulators; transcriptional regulator 1636929..1637894 Streptococcus pneumoniae AP200 9727744 YP_003877317.1 CDS SPAP_1731 NC_014494.1 1637929 1639203 R Operon 786 Gene 1 COG1257 Hydroxymethylglutaryl-CoA reductase; hydroxymethylglutaryl-CoA reductase complement(1637929..1639203) Streptococcus pneumoniae AP200 9727745 YP_003877318.1 CDS SPAP_1732 NC_014494.1 1639203 1640399 R Operon 786 Gene 2 COG3425 3-hydroxy-3-methylglutaryl CoA synthase; 3-hydroxy-3-methylglutaryl CoA synthase complement(1639203..1640399) Streptococcus pneumoniae AP200 9727746 YP_003877319.1 CDS SPAP_1733 NC_014494.1 1640506 1640793 R Operon 787 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1640506..1640793) Streptococcus pneumoniae AP200 9727747 YP_003877320.1 CDS SPAP_1734 NC_014494.1 1640822 1641121 R transposase-like protein, IS1381 ISSpn7 complement(1640822..1641121) Streptococcus pneumoniae AP200 9727748 YP_003877321.1 CDS SPAP_1735 NC_014494.1 1641509 1641958 R Operon 788 Gene 1 COG3610 Uncharacterized conserved protein; hypothetical protein complement(1641509..1641958) Streptococcus pneumoniae AP200 9727749 YP_003877322.1 CDS SPAP_1736 NC_014494.1 1641960 1642718 R Operon 788 Gene 2 COG2966 Uncharacterized conserved protein; hypothetical protein complement(1641960..1642718) Streptococcus pneumoniae AP200 9727750 YP_003877323.1 CDS SPAP_1737 NC_014494.1 1642833 1644812 R Operon 789 Gene 1 COG0515 Serine/threonine protein kinase; serine/threonine protein kinase complement(1642833..1644812) Streptococcus pneumoniae AP200 9727751 YP_003877324.1 CDS SPAP_1738 NC_014494.1 1644809 1645549 R Operon 789 Gene 2 COG0631 Serine/threonine protein phosphatase; serine/threonine protein phosphatase complement(1644809..1645549) Streptococcus pneumoniae AP200 9727752 YP_003877325.1 CDS SPAP_1739 NC_014494.1 1645564 1646877 R Operon 789 Gene 3 COG0144 tRNA and rRNA cytosine-C5-methylases; tRNA and rRNA cytosine-C5-methylase complement(1645564..1646877) Streptococcus pneumoniae AP200 9727753 YP_003877326.1 CDS SPAP_1740 NC_014494.1 1646870 1647805 R Operon 789 Gene 4 COG0223 Methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase complement(1646870..1647805) Streptococcus pneumoniae AP200 9727754 YP_003877327.1 CDS SPAP_1741 NC_014494.1 1647818 1650214 R Operon 789 Gene 5 COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; primosomal protein N' complement(1647818..1650214) Streptococcus pneumoniae AP200 9727755 YP_003877328.1 CDS SPAP_1742 NC_014494.1 1650280 1650594 R Operon 789 Gene 6 COG1758 DNA-directed RNA polymerase, subunit K/omega; DNA-directed RNA polymerase subunit K/omega complement(1650280..1650594) Streptococcus pneumoniae AP200 9727756 YP_003877329.1 CDS SPAP_1743 NC_014494.1 1650619 1651245 R Operon 789 Gene 7 COG0194 Guanylate kinase; guanylate kinase complement(1650619..1651245) Streptococcus pneumoniae AP200 9727757 YP_003877330.1 CDS SPAP_1744 NC_014494.1 1651375 1652988 R Operon 790 Gene 1 COG1418 Predicted HD superfamily hydrolase; putative HD superfamily hydrolase complement(1651375..1652988) Streptococcus pneumoniae AP200 9727758 YP_003877331.1 CDS SPAP_1745 NC_014494.1 1652933 1653076 D Operon 791 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1652933..1653076 Streptococcus pneumoniae AP200 9727759 YP_003877332.1 CDS SPAP_1746 NC_014494.1 1653179 1653433 R Operon 792 Gene 1 COG4115 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1653179..1653433) Streptococcus pneumoniae AP200 9727760 YP_003877333.1 CDS SPAP_1747 NC_014494.1 1653437 1653691 R Operon 792 Gene 2 COG2161 Antitoxin of toxin-antitoxin stability system; antitoxin of toxin-antitoxin stability system complement(1653437..1653691) Streptococcus pneumoniae AP200 9727761 YP_003877334.1 CDS SPAP_1748 NC_014494.1 1653929 1655026 R Operon 793 Gene 1 COG1323 Predicted nucleotidyltransferase; putative nucleotidyltransferase complement(1653929..1655026) Streptococcus pneumoniae AP200 9727762 YP_003877335.1 CDS SPAP_1749 NC_014494.1 1655036 1655782 R Operon 793 Gene 2 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase complement(1655036..1655782) Streptococcus pneumoniae AP200 9727763 YP_003877336.1 CDS SPAP_1750 NC_014494.1 1655885 1656238 R Operon 794 Gene 1 COG0799 Uncharacterized homolog of plant Iojap protein; plant Iojap-like protein complement(1655885..1656238) Streptococcus pneumoniae AP200 9727764 YP_003877337.1 CDS SPAP_1751 NC_014494.1 1656251 1656751 R Operon 794 Gene 2 COG1335 Amidases related to nicotinamidase; amidase complement(1656251..1656751) Streptococcus pneumoniae AP200 9727765 YP_003877338.1 CDS SPAP_1752 NC_014494.1 1656752 1657345 R Operon 794 Gene 3 COG1713 Predicted HD superfamily hydrolase involved in NAD metabolism; putative HD superfamily hydrolase complement(1656752..1657345) Streptococcus pneumoniae AP200 9727766 YP_003877339.1 CDS SPAP_1753 NC_014494.1 1657345 1657974 R Operon 794 Gene 4 COG1057 Nicotinic acid mononucleotide adenylyltransferase; nicotinic acid mononucleotide adenylyltransferase complement(1657345..1657974) Streptococcus pneumoniae AP200 9727767 YP_003877340.1 CDS SPAP_1754 NC_014494.1 1658026 1658337 R Operon 794 Gene 5 protein supported gi|15901580|ref|NP_346184.1| hypothetical protein SP_1748; hypothetical protein complement(1658026..1658337) Streptococcus pneumoniae AP200 9727768 YP_003877341.1 CDS SPAP_1755 NC_014494.1 1658552 1659658 R Operon 795 Gene 1 COG1161 Predicted GTPases; putative GTPase complement(1658552..1659658) Streptococcus pneumoniae AP200 9727769 YP_003877342.1 CDS SPAP_1756 NC_014494.1 1659661 1660188 R Operon 795 Gene 2 COG2179 Predicted hydrolase of the HAD superfamily; putative HAD superfamily hydrolase complement(1659661..1660188) Streptococcus pneumoniae AP200 9727770 YP_003877343.1 CDS SPAP_1757 NC_014494.1 1660203 1661111 R Operon 795 Gene 3 COG0598 Mg2+ and Co2+ transporters; Mg2+ and Co2+ transporter complement(1660203..1661111) Streptococcus pneumoniae AP200 9727771 YP_003877344.1 CDS SPAP_1758 NC_014494.1 1661168 1661728 R Operon 795 Gene 4 COG0668 Small-conductance mechanosensitive channel; small-conductance mechanosensitive channel complement(1661168..1661728) Streptococcus pneumoniae AP200 9727772 YP_003877345.1 CDS SPAP_1759 NC_014494.1 1661932 1662120 D Operon 796 Gene 1 COG3633 Na+/serine symporter; Na+/serine symporter 1661932..1662120 Streptococcus pneumoniae AP200 9727773 YP_003877346.1 CDS SPAP_1760 NC_014494.1 1662117 1663085 D Operon 796 Gene 2 COG3633 Na+/serine symporter; Na+/serine symporter 1662117..1663085 Streptococcus pneumoniae AP200 9727774 YP_003877347.1 CDS SPAP_1761 NC_014494.1 1663153 1664106 D Operon 796 Gene 3 COG4129 Predicted membrane protein; hypothetical protein 1663153..1664106 Streptococcus pneumoniae AP200 9727775 YP_003877348.1 CDS SPAP_1762 NC_014494.1 1664250 1664630 D Operon 797 Gene 1 COG1846 Transcriptional regulators; transcriptional regulator 1664250..1664630 Streptococcus pneumoniae AP200 9727776 YP_003877349.1 CDS SPAP_1763 NC_014494.1 1664730 1664951 D Operon 798 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1664730..1664951 Streptococcus pneumoniae AP200 9727777 YP_003877350.1 CDS SPAP_1764 NC_014494.1 1664968 1665282 D Operon 798 Gene 2 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin 1664968..1665282 Streptococcus pneumoniae AP200 9727778 YP_003877351.1 CDS SPAP_1765 NC_014494.1 1665588 1666121 D Operon 799 Gene 1 protein supported gi|148994988|ref|ZP_01823966.1| ribosomal protein L11 methyltransferase; hypothetical protein 1665588..1666121 Streptococcus pneumoniae AP200 9727779 YP_003877352.1 CDS SPAP_1766 NC_014494.1 1666331 1666999 R Operon 800 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease complement(1666331..1666999) Streptococcus pneumoniae AP200 9727780 YP_003877353.1 CDS SPAP_1767 NC_014494.1 1667110 1667901 R Operon 800 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1667110..1667901) Streptococcus pneumoniae AP200 9727781 YP_003877354.1 CDS SPAP_1768 NC_014494.1 1668326 1669090 R Operon 801 Gene 1 COG0842 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease complement(1668326..1669090) Streptococcus pneumoniae AP200 9727782 YP_003877355.1 CDS SPAP_1769 NC_014494.1 1669083 1669853 R Operon 801 Gene 2 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase complement(1669083..1669853) Streptococcus pneumoniae AP200 9727783 YP_003877356.1 CDS SPAP_1770 NC_014494.1 1670102 1670779 D Operon 802 Gene 1 COG0640 Predicted transcriptional regulators; putative transcriptional regulator 1670102..1670779 Streptococcus pneumoniae AP200 9727784 YP_003877357.1 CDS SPAP_1771 NC_014494.1 1670839 1672635 R Operon 803 Gene 1 COG1164 Oligoendopeptidase F; oligoendopeptidase F complement(1670839..1672635) Streptococcus pneumoniae AP200 9727785 YP_003877358.1 CDS SPAP_1772 NC_014494.1 1672646 1673389 R Operon 803 Gene 2 COG1385 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1672646..1673389) Streptococcus pneumoniae AP200 9727786 YP_003877359.1 CDS SPAP_1773 NC_014494.1 1673391 1674341 R Operon 803 Gene 3 protein supported gi|148997825|ref|ZP_01825389.1| ribosomal protein L11 methyltransferase; hypothetical protein complement(1673391..1674341) Streptococcus pneumoniae AP200 9727787 YP_003877360.1 CDS SPAP_1774 NC_014494.1 1674477 1674905 R Operon 804 Gene 1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; NTP pyrophosphohydrolase including oxidative damage repair enzymes complement(1674477..1674905) Streptococcus pneumoniae AP200 9727788 YP_003877361.1 CDS SPAP_1775 NC_014494.1 1674886 1675974 R Operon 804 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1674886..1675974) Streptococcus pneumoniae AP200 9727789 YP_003877362.1 CDS SPAP_1776 NC_014494.1 1675993 1676463 R Operon 804 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1675993..1676463) Streptococcus pneumoniae AP200 9727790 YP_003877363.1 CDS SPAP_1777 NC_014494.1 1676754 1677206 R Operon 805 Gene 1 COG1598 Uncharacterized conserved protein; hypothetical protein complement(1676754..1677206) Streptococcus pneumoniae AP200 9727791 YP_003877364.1 CDS SPAP_1778 NC_014494.1 1677243 1677422 R Operon 805 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1677243..1677422) Streptococcus pneumoniae AP200 9727792 YP_003877365.1 CDS SPAP_1779 NC_014494.1 1677559 1677666 R Operon 806 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1677559..1677666) Streptococcus pneumoniae AP200 9727793 YP_003877366.1 CDS SPAP_1780 NC_014494.1 1677903 1678124 R Operon 807 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1677903..1678124) Streptococcus pneumoniae AP200 9727794 YP_003877367.1 CDS SPAP_1781 NC_014494.1 1678416 1679687 D Operon 808 Gene 1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; ATPase 1678416..1679687 Streptococcus pneumoniae AP200 9727795 YP_003877368.1 CDS SPAP_1783 NC_014494.1 1680232 1681551 R Operon 809 Gene 1 COG1621 Beta-fructosidases (levanase/invertase); levanase/invertase complement(1680232..1681551) Streptococcus pneumoniae AP200 9727797 YP_003877369.1 CDS SPAP_1784 NC_014494.1 1681561 1683177 R Operon 809 Gene 2 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein complement(1681561..1683177) Streptococcus pneumoniae AP200 9727798 YP_003877370.1 CDS SPAP_1785 NC_014494.1 1683206 1684096 R Operon 809 Gene 3 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease complement(1683206..1684096) Streptococcus pneumoniae AP200 9727799 YP_003877371.1 CDS SPAP_1786 NC_014494.1 1684107 1685024 R Operon 809 Gene 4 COG4209 ABC-type polysaccharide transport system, permease component; polysaccharide ABC transporter permease complement(1684107..1685024) Streptococcus pneumoniae AP200 9727800 YP_003877372.1 CDS SPAP_1787 NC_014494.1 1685174 1686175 R Operon 810 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator complement(1685174..1686175) Streptococcus pneumoniae AP200 9727801 YP_003877373.1 CDS SPAP_1788 NC_014494.1 1686536 1688017 R Operon 811 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1686536..1688017) Streptococcus pneumoniae AP200 9727802 YP_003877374.1 CDS SPAP_1789 NC_014494.1 1688460 1688624 D Operon 812 Gene 1 COG2261 Predicted membrane protein; hypothetical protein 1688460..1688624 Streptococcus pneumoniae AP200 9727803 YP_003877375.1 CDS SPAP_1790 NC_014494.1 1688708 1689274 D Operon 812 Gene 2 Putative gene predicted by FgenesB; hypothetical protein 1688708..1689274 Streptococcus pneumoniae AP200 9727804 YP_003877376.1 CDS SPAP_1791 NC_014494.1 1689286 1689456 D Operon 812 Gene 3 COG5547 Small integral membrane protein; small integral membrane protein 1689286..1689456 Streptococcus pneumoniae AP200 9727805 YP_003877377.1 CDS SPAP_1792 NC_014494.1 1689495 1690103 D Operon 812 Gene 4 COG1302 Uncharacterized protein conserved in bacteria; hypothetical protein 1689495..1690103 Streptococcus pneumoniae AP200 9727806 YP_003877378.1 CDS SPAP_1793 NC_014494.1 1690134 1690337 D Operon 812 Gene 5 COG3237 Uncharacterized protein conserved in bacteria; hypothetical protein 1690134..1690337 Streptococcus pneumoniae AP200 9727807 YP_003877379.1 CDS SPAP_1794 NC_014494.1 1690430 1690669 R Operon 813 Gene 1 COG3666 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_5 complement(1690430..1690669) Streptococcus pneumoniae AP200 9727808 YP_003877380.1 CDS SPAP_1795 NC_014494.1 1690948 1691193 D Operon 814 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1690948..1691193 Streptococcus pneumoniae AP200 9727809 YP_003877381.1 CDS SPAP_1796 NC_014494.1 1691471 1691899 R Operon 815 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1691471..1691899) Streptococcus pneumoniae AP200 9727810 YP_003877382.1 CDS SPAP_1797 NC_014494.1 1692256 1693104 R Operon 816 Gene 1 COG1262 Uncharacterized conserved protein; hypothetical protein complement(1692256..1693104) Streptococcus pneumoniae AP200 9727811 YP_003877383.1 CDS SPAP_1798 NC_014494.1 1693101 1694576 R Operon 816 Gene 2 COG3119 Arylsulfatase A and related enzymes; arylsulfatase A-like enzyme complement(1693101..1694576) Streptococcus pneumoniae AP200 9727812 YP_003877384.1 CDS SPAP_1799 NC_014494.1 1694900 1695397 R Operon 817 Gene 1 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC complement(1694900..1695397) Streptococcus pneumoniae AP200 9727813 YP_003877385.1 CDS SPAP_1800 NC_014494.1 1695339 1696256 R Operon 817 Gene 2 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC complement(1695339..1696256) Streptococcus pneumoniae AP200 9727814 YP_003877386.1 CDS SPAP_1801 NC_014494.1 1696266 1696583 R Operon 817 Gene 3 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA complement(1696266..1696583) Streptococcus pneumoniae AP200 9727815 YP_003877387.1 CDS SPAP_1802 NC_014494.1 1696600 1696917 R Operon 817 Gene 4 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB complement(1696600..1696917) Streptococcus pneumoniae AP200 9727816 YP_003877388.1 CDS SPAP_1803 NC_014494.1 1696932 1697828 R Operon 817 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(1696932..1697828) Streptococcus pneumoniae AP200 9727817 YP_003877389.1 CDS SPAP_1804 NC_014494.1 1697831 1699093 R Operon 817 Gene 6 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC complement(1697831..1699093) Streptococcus pneumoniae AP200 9727818 YP_003877390.1 CDS SPAP_1805 NC_014494.1 1699373 1700551 D Operon 818 Gene 1 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase 1699373..1700551 Streptococcus pneumoniae AP200 9727819 YP_003877391.1 CDS SPAP_1806 NC_014494.1 1700779 1701225 R Operon 819 Gene 1 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; acetyltransferase complement(1700779..1701225) Streptococcus pneumoniae AP200 9727820 YP_003877392.1 CDS SPAP_1807 NC_014494.1 1701295 1701954 D Operon 820 Gene 1 COG1989 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases; type II secretory pathway, prepilin signal peptidase PulO-like peptidase 1701295..1701954 Streptococcus pneumoniae AP200 9727821 YP_003877393.1 CDS SPAP_1808 NC_014494.1 1702006 1703157 R Operon 821 Gene 1 COG2856 Predicted Zn peptidase; putative Zn peptidase complement(1702006..1703157) Streptococcus pneumoniae AP200 9727822 YP_003877394.1 CDS SPAP_1809 NC_014494.1 1703172 1703903 R Operon 821 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1703172..1703903) Streptococcus pneumoniae AP200 9727823 YP_003877395.1 CDS SPAP_1810 NC_014494.1 1704205 1704981 R Operon 822 Gene 1 protein supported gi|148997862|ref|ZP_01825426.1| ribosomal protein L11 methyltransferase; hypothetical protein complement(1704205..1704981) Streptococcus pneumoniae AP200 9727824 YP_003877396.1 CDS SPAP_1811 NC_014494.1 1704974 1706197 R Operon 822 Gene 2 COG0133 Tryptophan synthase beta chain; tryptophan synthase beta chain complement(1704974..1706197) Streptococcus pneumoniae AP200 9727825 YP_003877397.1 CDS SPAP_1812 NC_014494.1 1706175 1706774 R Operon 822 Gene 3 COG0135 Phosphoribosylanthranilate isomerase; phosphoribosylanthranilate isomerase complement(1706175..1706774) Streptococcus pneumoniae AP200 9727826 YP_003877398.1 CDS SPAP_1813 NC_014494.1 1706761 1707528 R Operon 822 Gene 4 COG0134 Indole-3-glycerol phosphate synthase; indole-3-glycerol phosphate synthase complement(1706761..1707528) Streptococcus pneumoniae AP200 9727827 YP_003877399.1 CDS SPAP_1814 NC_014494.1 1707525 1708529 R Operon 822 Gene 5 COG0547 Anthranilate phosphoribosyltransferase; anthranilate phosphoribosyltransferase complement(1707525..1708529) Streptococcus pneumoniae AP200 9727828 YP_003877400.1 CDS SPAP_1815 NC_014494.1 1708540 1709106 R Operon 822 Gene 6 COG0512 Anthranilate/para-aminobenzoate synthases component II; anthranilate/para-aminobenzoate synthases component II complement(1708540..1709106) Streptococcus pneumoniae AP200 9727829 YP_003877401.1 CDS SPAP_1816 NC_014494.1 1709103 1710464 R Operon 822 Gene 7 COG0147 Anthranilate/para-aminobenzoate synthases component I; anthranilate/para-aminobenzoate synthases component I complement(1709103..1710464) Streptococcus pneumoniae AP200 9727830 YP_003877402.1 CDS SPAP_1817 NC_014494.1 1711605 1712606 R Operon 823 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator complement(1711605..1712606) Streptococcus pneumoniae AP200 9727831 YP_003877403.1 CDS SPAP_1818 NC_014494.1 1712714 1712905 R Operon 824 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1712714..1712905) Streptococcus pneumoniae AP200 9727832 YP_003877404.1 CDS SPAP_1819 NC_014494.1 1713178 1713888 R Operon 825 Gene 1 COG1285 Uncharacterized membrane protein; hypothetical protein complement(1713178..1713888) Streptococcus pneumoniae AP200 9727833 YP_003877405.1 CDS SPAP_1820 NC_014494.1 1713891 1715582 R Operon 825 Gene 2 COG1178 ABC-type Fe3+ transport system, permease component; Fe3+ ABC transporter permease complement(1713891..1715582) Streptococcus pneumoniae AP200 9727834 YP_003877406.1 CDS SPAP_1821 NC_014494.1 1715594 1716604 R Operon 825 Gene 3 COG3842 ABC-type spermidine/putrescine transport systems, ATPase components; spermidine/putrescine ABC transporter ATPase complement(1715594..1716604) Streptococcus pneumoniae AP200 9727835 YP_003877407.1 CDS SPAP_1822 NC_014494.1 1716708 1717775 R Operon 825 Gene 4 COG1840 ABC-type Fe3+ transport system, periplasmic component; Fe3+ ABC transporter periplasmic protein complement(1716708..1717775) Streptococcus pneumoniae AP200 9727836 YP_003877408.1 CDS SPAP_1823 NC_014494.1 1717800 1718459 R Operon 825 Gene 5 COG5255 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1717800..1718459) Streptococcus pneumoniae AP200 9727837 YP_003877409.1 CDS SPAP_1824 NC_014494.1 1718639 1719649 R Operon 826 Gene 1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase complement(1718639..1719649) Streptococcus pneumoniae AP200 9727838 YP_003877410.1 CDS SPAP_1825 NC_014494.1 1719662 1721137 R Operon 826 Gene 2 COG4468 Galactose-1-phosphate uridyltransferase; galactose-1-phosphate uridyltransferase complement(1719662..1721137) Streptococcus pneumoniae AP200 9727839 YP_003877411.1 CDS SPAP_1826 NC_014494.1 1721150 1721791 R Operon 826 Gene 3 COG0704 Phosphate uptake regulator; phosphate uptake regulator complement(1721150..1721791) Streptococcus pneumoniae AP200 9727840 YP_003877412.1 CDS SPAP_1827 NC_014494.1 1721849 1722250 R Operon 826 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1721849..1722250) Streptococcus pneumoniae AP200 9727841 YP_003877413.1 CDS SPAP_1828 NC_014494.1 1722404 1722700 R Operon 827 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1722404..1722700) Streptococcus pneumoniae AP200 9727842 YP_003877414.1 CDS SPAP_1829 NC_014494.1 1722684 1724810 R Operon 827 Gene 2 COG5434 Endopolygalacturonase; endopolygalacturonase complement(1722684..1724810) Streptococcus pneumoniae AP200 9727843 YP_003877415.1 CDS SPAP_1830 NC_014494.1 1725758 1725931 D Operon 828 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1725758..1725931 Streptococcus pneumoniae AP200 9727844 YP_003877416.1 CDS SPAP_1831 NC_014494.1 1725973 1727199 R Operon 829 Gene 1 COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; hypothetical protein complement(1725973..1727199) Streptococcus pneumoniae AP200 9727845 YP_003877417.1 CDS SPAP_1832 NC_014494.1 1727242 1727934 R Operon 829 Gene 2 COG2148 Sugar transferases involved in lipopolysaccharide synthesis; sugar transferase complement(1727242..1727934) Streptococcus pneumoniae AP200 9727846 YP_003877418.1 CDS SPAP_1833 NC_014494.1 1728107 1729858 R Operon 830 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1728107..1729858) Streptococcus pneumoniae AP200 9727847 YP_003877419.1 CDS SPAP_1834 NC_014494.1 1729848 1731593 R Operon 830 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1729848..1731593) Streptococcus pneumoniae AP200 9727848 YP_003877420.1 CDS SPAP_1835 NC_014494.1 1731799 1732176 R Operon 831 Gene 1 COG2323 Predicted membrane protein; hypothetical protein complement(1731799..1732176) Streptococcus pneumoniae AP200 9727849 YP_003877421.1 CDS SPAP_1836 NC_014494.1 1732248 1732517 R Operon 831 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1732248..1732517) Streptococcus pneumoniae AP200 9727850 YP_003877422.1 CDS SPAP_1837 NC_014494.1 1732548 1732703 R Operon 831 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1732548..1732703) Streptococcus pneumoniae AP200 9727851 YP_003877423.1 CDS SPAP_1838 NC_014494.1 1732837 1733664 D Operon 832 Gene 1 COG0708 Exonuclease III; exonuclease III 1732837..1733664 Streptococcus pneumoniae AP200 9727852 YP_003877424.1 CDS SPAP_1839 NC_014494.1 1733676 1733927 D Operon 832 Gene 2 COG0346 Lactoylglutathione lyase and related lyases; lactoylglutathione lyase-like lyase 1733676..1733927 Streptococcus pneumoniae AP200 9727853 YP_003877425.1 CDS SPAP_1840 NC_014494.1 1733934 1734062 D Operon 832 Gene 3 Putative gene predicted by FgenesB; hypothetical protein 1733934..1734062 Streptococcus pneumoniae AP200 9727854 YP_003877426.1 CDS SPAP_1841 NC_014494.1 1734798 1734917 D Operon 833 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1734798..1734917 Streptococcus pneumoniae AP200 9727855 YP_003877427.1 CDS SPAP_1842 NC_014494.1 1734940 1735521 D Operon 833 Gene 2 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein 1734940..1735521 Streptococcus pneumoniae AP200 9727856 YP_003877428.1 CDS SPAP_1843 NC_014494.1 1735521 1736783 D Operon 833 Gene 3 COG2233 Xanthine/uracil permeases; Xanthine/uracil permease 1735521..1736783 Streptococcus pneumoniae AP200 9727857 YP_003877429.1 CDS SPAP_1844 NC_014494.1 1736870 1737736 R Operon 834 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1736870..1737736) Streptococcus pneumoniae AP200 9727858 YP_003877430.1 CDS SPAP_1845 NC_014494.1 1737723 1738493 R Operon 834 Gene 2 COG0863 DNA modification methylase; DNA modification methylase complement(1737723..1738493) Streptococcus pneumoniae AP200 9727859 YP_003877431.1 CDS SPAP_1846 NC_014494.1 1738519 1739373 R Operon 834 Gene 3 COG0338 Site-specific DNA methylase; site-specific DNA methylase complement(1738519..1739373) Streptococcus pneumoniae AP200 9727860 YP_003877432.1 CDS SPAP_1847 NC_014494.1 1739530 1739934 R Operon 835 Gene 1 COG2050 Uncharacterized protein, possibly involved in aromatic compounds catabolism; hypothetical protein complement(1739530..1739934) Streptococcus pneumoniae AP200 9727861 YP_003877433.1 CDS SPAP_1848 NC_014494.1 1740004 1741485 R Operon 835 Gene 2 COG4468 Galactose-1-phosphate uridyltransferase; galactose-1-phosphate uridyltransferase complement(1740004..1741485) Streptococcus pneumoniae AP200 9727862 YP_003877434.1 CDS SPAP_1849 NC_014494.1 1741504 1742682 R Operon 835 Gene 3 COG0153 Galactokinase; galactokinase complement(1741504..1742682) Streptococcus pneumoniae AP200 9727863 YP_003877435.1 CDS SPAP_1850 NC_014494.1 1742847 1743854 D Operon 836 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator 1742847..1743854 Streptococcus pneumoniae AP200 9727864 YP_003877436.1 CDS SPAP_1851 NC_014494.1 1743900 1744937 R Operon 837 Gene 1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase complement(1743900..1744937) Streptococcus pneumoniae AP200 9727865 YP_003877437.1 CDS SPAP_1852 NC_014494.1 1744938 1745291 R Operon 837 Gene 2 COG0789 Predicted transcriptional regulators; putative transcriptional regulator complement(1744938..1745291) Streptococcus pneumoniae AP200 9727866 YP_003877438.1 CDS SPAP_1853 NC_014494.1 1745535 1746425 R Operon 838 Gene 1 COG1230 Co/Zn/Cd efflux system component; Co/Zn/Cd efflux system protein complement(1745535..1746425) Streptococcus pneumoniae AP200 9727867 YP_003877439.1 CDS SPAP_1854 NC_014494.1 1746558 1747094 D Operon 839 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 1746558..1747094 Streptococcus pneumoniae AP200 9727868 YP_003877440.1 CDS SPAP_1855 NC_014494.1 1747261 1748067 R Operon 840 Gene 1 COG3201 Nicotinamide mononucleotide transporter; nicotinamide mononucleotide transporter complement(1747261..1748067) Streptococcus pneumoniae AP200 9727869 YP_003877441.1 CDS SPAP_1856 NC_014494.1 1748412 1749932 R Operon 841 Gene 1 COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system; osmoprotectant binding protein; ABC transporter periplasmic glycine betaine/choline-binding (lipo)protein complement(1748412..1749932) Streptococcus pneumoniae AP200 9727870 YP_003877442.1 CDS SPAP_1857 NC_014494.1 1749925 1750653 R Operon 841 Gene 2 COG1125 ABC-type proline/glycine betaine transport systems, ATPase components; proline/glycine betaine ABC transporter ATPase complement(1749925..1750653) Streptococcus pneumoniae AP200 9727871 YP_003877443.1 CDS SPAP_1858 NC_014494.1 1750668 1751432 R Operon 841 Gene 3 COG4922 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1750668..1751432) Streptococcus pneumoniae AP200 9727872 YP_003877444.1 CDS SPAP_1859 NC_014494.1 1751436 1751879 R Operon 841 Gene 4 COG1846 Transcriptional regulators; transcriptional regulator complement(1751436..1751879) Streptococcus pneumoniae AP200 9727873 YP_003877445.1 CDS SPAP_1860 NC_014494.1 1752561 1752857 R Operon 842 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1752561..1752857) Streptococcus pneumoniae AP200 9727874 YP_003877446.1 CDS SPAP_1861 NC_014494.1 1752879 1753943 R Operon 842 Gene 2 COG1363 Cellulase M and related proteins; cellulase M-like proteins complement(1752879..1753943) Streptococcus pneumoniae AP200 9727875 YP_003877447.1 CDS SPAP_1862 NC_014494.1 1754343 1755044 D Operon 843 Gene 1 COG1087 UDP-glucose 4-epimerase; UDP-glucose 4-epimerase 1754343..1755044 Streptococcus pneumoniae AP200 9727876 YP_003877448.1 CDS SPAP_1863 NC_014494.1 1755467 1756426 D Operon 844 Gene 1 COG4606 ABC-type enterochelin transport system, permease component; enterochelin ABC transporter permease 1755467..1756426 Streptococcus pneumoniae AP200 9727877 YP_003877449.1 CDS SPAP_1864 NC_014494.1 1756416 1757372 D Operon 844 Gene 2 COG4605 ABC-type enterochelin transport system, permease component; enterochelin ABC transporter permease 1756416..1757372 Streptococcus pneumoniae AP200 9727878 YP_003877450.1 CDS SPAP_1865 NC_014494.1 1757369 1758121 D Operon 844 Gene 3 COG4604 ABC-type enterochelin transport system, ATPase component; enterochelin ABC transporter ATPase 1757369..1758121 Streptococcus pneumoniae AP200 9727879 YP_003877451.1 CDS SPAP_1866 NC_014494.1 1758217 1759182 D Operon 844 Gene 4 COG4607 ABC-type enterochelin transport system, periplasmic component; enterochelin ABC transporter periplasmic protein 1758217..1759182 Streptococcus pneumoniae AP200 9727880 YP_003877452.1 CDS SPAP_1867 NC_014494.1 1759407 1759649 R Operon 845 Gene 1 COG0759 Uncharacterized conserved protein; hypothetical protein complement(1759407..1759649) Streptococcus pneumoniae AP200 9727881 YP_003877453.1 CDS SPAP_1868 NC_014494.1 1759649 1760371 R Operon 845 Gene 2 COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; 16S rRNA uridine-516 pseudouridylate synthase-like pseudouridylate synthase complement(1759649..1760371) Streptococcus pneumoniae AP200 9727882 YP_003877454.1 CDS SPAP_1869 NC_014494.1 1760358 1760927 R Operon 845 Gene 3 COG1386 Predicted transcriptional regulator containing the HTH domain; putative transcriptional regulator complement(1760358..1760927) Streptococcus pneumoniae AP200 9727883 YP_003877455.1 CDS SPAP_1870 NC_014494.1 1760946 1761674 R Operon 845 Gene 4 COG1354 Uncharacterized conserved protein; hypothetical protein complement(1760946..1761674) Streptococcus pneumoniae AP200 9727884 YP_003877456.1 CDS SPAP_1871 NC_014494.1 1761678 1762415 R Operon 845 Gene 5 COG0582 Integrase; integrase complement(1761678..1762415) Streptococcus pneumoniae AP200 9727885 YP_003877457.1 CDS SPAP_1872 NC_014494.1 1762406 1762867 R Operon 845 Gene 6 COG0517 FOG: CBS domain; hypothetical protein complement(1762406..1762867) Streptococcus pneumoniae AP200 9727886 YP_003877458.1 CDS SPAP_1873 NC_014494.1 1762864 1763385 R Operon 845 Gene 7 COG0622 Predicted phosphoesterase; putative phosphoesterase complement(1762864..1763385) Streptococcus pneumoniae AP200 9727887 YP_003877459.1 CDS SPAP_1874 NC_014494.1 1763361 1764332 R Operon 845 Gene 8 protein supported gi|157155704|ref|YP_001464307.1| putative deoxyribonucleotide triphosphate pyrophosphatase; hypothetical protein complement(1763361..1764332) Streptococcus pneumoniae AP200 9727888 YP_003877460.1 CDS SPAP_1875 NC_014494.1 1764329 1765123 R Operon 845 Gene 9 COG0796 Glutamate racemase; glutamate racemase complement(1764329..1765123) Streptococcus pneumoniae AP200 9727889 YP_003877461.1 CDS SPAP_1876 NC_014494.1 1765344 1765580 R Operon 846 Gene 1 COG3763 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1765344..1765580) Streptococcus pneumoniae AP200 9727890 YP_003877462.1 CDS SPAP_1877 NC_014494.1 1765836 1767461 R Operon 847 Gene 1 COG0366 Glycosidases; glycosidase complement(1765836..1767461) Streptococcus pneumoniae AP200 9727891 YP_003877463.1 CDS SPAP_1878 NC_014494.1 1767639 1769606 R Operon 847 Gene 2 COG1263 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific; PTS system glucose/maltose/N-acetylglucosamine-specific transporter subunit IIC complement(1767639..1769606) Streptococcus pneumoniae AP200 9727892 YP_003877464.1 CDS SPAP_1879 NC_014494.1 1769791 1770501 D Operon 848 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator 1769791..1770501 Streptococcus pneumoniae AP200 9727893 YP_003877465.1 CDS SPAP_1880 NC_014494.1 1770534 1771337 R Operon 849 Gene 1 COG1101 ABC-type uncharacterized transport system, ATPase component; ABC transporter ATPase complement(1770534..1771337) Streptococcus pneumoniae AP200 9727894 YP_003877466.1 CDS SPAP_1881 NC_014494.1 1771350 1771778 R Operon 849 Gene 2 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease complement(1771350..1771778) Streptococcus pneumoniae AP200 9727895 YP_003877467.1 CDS SPAP_1882 NC_014494.1 1771787 1772227 R Operon 849 Gene 3 COG4120 ABC-type uncharacterized transport system, permease component; ABC transporter permease complement(1771787..1772227) Streptococcus pneumoniae AP200 9727896 YP_003877468.1 CDS SPAP_1883 NC_014494.1 1772239 1772601 R Operon 849 Gene 4 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic complement(1772239..1772601) Streptococcus pneumoniae AP200 9727897 YP_003877469.1 CDS SPAP_1884 NC_014494.1 1772662 1773048 R Operon 849 Gene 5 COG2984 ABC-type uncharacterized transport system, periplasmic component; ABC transporter periplasmic complement(1772662..1773048) Streptococcus pneumoniae AP200 9727898 YP_003877470.1 CDS SPAP_1885 NC_014494.1 1773666 1774622 R Operon 850 Gene 1 protein supported gi|163765018|ref|ZP_02172066.1| ribosomal protein L9; hypothetical protein complement(1773666..1774622) Streptococcus pneumoniae AP200 9727899 YP_003877471.1 CDS SPAP_1886 NC_014494.1 1774603 1775670 R Operon 850 Gene 2 COG0444 ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component; dipeptide/oligopeptide/nickel ABC transporter ATPase complement(1774603..1775670) Streptococcus pneumoniae AP200 9727900 YP_003877472.1 CDS SPAP_1887 NC_014494.1 1775679 1776605 R Operon 850 Gene 3 COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease complement(1775679..1776605) Streptococcus pneumoniae AP200 9727901 YP_003877473.1 CDS SPAP_1888 NC_014494.1 1776605 1778101 R Operon 850 Gene 4 COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems, permease components; dipeptide/oligopeptide/nickel ABC transporter permease complement(1776605..1778101) Streptococcus pneumoniae AP200 9727902 YP_003877474.1 CDS SPAP_1889 NC_014494.1 1778168 1780147 R Operon 850 Gene 5 COG4166 ABC-type oligopeptide transport system, periplasmic component; oligopeptide ABC transporter periplasmic protein complement(1778168..1780147) Streptococcus pneumoniae AP200 9727903 YP_003877475.1 CDS SPAP_1890 NC_014494.1 1780274 1780441 D Operon 851 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1780274..1780441 Streptococcus pneumoniae AP200 9727904 YP_003877476.1 CDS SPAP_1891 NC_014494.1 1780833 1782026 R Operon 852 Gene 1 COG3307 Lipid A core - O-antigen ligase and related enzymes; lipid A core - O-antigen ligase-like enzyme complement(1780833..1782026) Streptococcus pneumoniae AP200 9727905 YP_003877477.1 CDS SPAP_1892 NC_014494.1 1782164 1783606 R Operon 853 Gene 1 COG0366 Glycosidases; glycosidase complement(1782164..1783606) Streptococcus pneumoniae AP200 9727906 YP_003877478.1 CDS SPAP_1893 NC_014494.1 1783917 1784750 R Operon 854 Gene 1 COG0395 ABC-type sugar transport system, permease component; sugar ABC transporter permease complement(1783917..1784750) Streptococcus pneumoniae AP200 9727907 YP_003877479.1 CDS SPAP_1894 NC_014494.1 1784764 1785630 R Operon 854 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease complement(1784764..1785630) Streptococcus pneumoniae AP200 9727908 YP_003877480.1 CDS SPAP_1895 NC_014494.1 1785644 1786903 R Operon 854 Gene 3 COG1653 ABC-type sugar transport system, periplasmic component; sugar ABC transporter periplasmic protein complement(1785644..1786903) Streptococcus pneumoniae AP200 9727909 YP_003877481.1 CDS SPAP_1896 NC_014494.1 1786938 1789100 R Operon 854 Gene 4 COG3345 Alpha-galactosidase; alpha-galactosidase complement(1786938..1789100) Streptococcus pneumoniae AP200 9727910 YP_003877482.1 CDS SPAP_1897 NC_014494.1 1789208 1790068 D Operon 855 Gene 1 COG2207 AraC-type DNA-binding domain-containing proteins; AraC-type DNA-binding domain-containing protein 1789208..1790068 Streptococcus pneumoniae AP200 9727911 YP_003877483.1 CDS SPAP_1898 NC_014494.1 1790065 1791000 D Operon 855 Gene 2 COG0340 Biotin-(acetyl-CoA carboxylase) ligase; biotin-(acetyl-CoA carboxylase) ligase 1790065..1791000 Streptococcus pneumoniae AP200 9727912 YP_003877484.1 CDS SPAP_1919 NC_014494.1 1797918 1799273 R Operon 856 Gene 1 COG2265 SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase; SAM-dependent methyltransferase complement(1797918..1799273) Streptococcus pneumoniae AP200 9727933 YP_003877485.1 CDS SPAP_1920 NC_014494.1 1799353 1800087 D Operon 857 Gene 1 COG2137 Uncharacterized protein conserved in bacteria; hypothetical protein 1799353..1800087 Streptococcus pneumoniae AP200 9727934 YP_003877486.1 CDS SPAP_1921 NC_014494.1 1800176 1800709 D Operon 857 Gene 2 COG3557 Uncharacterized domain/protein associated with RNAses G and E; hypothetical protein 1800176..1800709 Streptococcus pneumoniae AP200 9727935 YP_003877487.1 CDS SPAP_1922 NC_014494.1 1801063 1801410 R Operon 858 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1801063..1801410) Streptococcus pneumoniae AP200 9727936 YP_003877488.1 CDS SPAP_1923 NC_014494.1 1801931 1802704 R Operon 859 Gene 1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase complement(1801931..1802704) Streptococcus pneumoniae AP200 9727937 YP_003877489.1 CDS SPAP_1924 NC_014494.1 1803152 1803478 R Operon 860 Gene 1 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1803152..1803478) Streptococcus pneumoniae AP200 9727938 YP_003877490.1 CDS SPAP_1925 NC_014494.1 1803578 1803742 R Operon 860 Gene 2 COG1636 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1803578..1803742) Streptococcus pneumoniae AP200 9727939 YP_003877491.1 CDS SPAP_1926 NC_014494.1 1803815 1803907 R Operon 860 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1803815..1803907) Streptococcus pneumoniae AP200 9727940 YP_003877492.1 CDS SPAP_1927 NC_014494.1 1804045 1805667 R Operon 861 Gene 1 protein supported gi|167855908|ref|ZP_02478658.1| 50S ribosomal protein L28; hypothetical protein complement(1804045..1805667) Streptococcus pneumoniae AP200 9727941 YP_003877493.1 CDS SPAP_1928 NC_014494.1 1805683 1805967 R Operon 861 Gene 2 COG0234 Co-chaperonin GroES (HSP10); co-chaperonin GroES complement(1805683..1805967) Streptococcus pneumoniae AP200 9727942 YP_003877494.1 CDS SPAP_1929 NC_014494.1 1806237 1806632 R Operon 862 Gene 1 COG0629 Single-stranded DNA-binding protein; single-stranded DNA-binding protein complement(1806237..1806632) Streptococcus pneumoniae AP200 9727943 YP_003877495.1 CDS SPAP_1930 NC_014494.1 1806710 1807471 R Operon 862 Gene 2 COG4221 Short-chain alcohol dehydrogenase of unknown specificity; short-chain alcohol dehydrogenase of unknown specificity complement(1806710..1807471) Streptococcus pneumoniae AP200 9727944 YP_003877496.1 CDS SPAP_1931 NC_014494.1 1807504 1808130 R Operon 862 Gene 3 COG0073 EMAP domain; EMAP domain protein complement(1807504..1808130) Streptococcus pneumoniae AP200 9727945 YP_003877497.1 CDS SPAP_1932 NC_014494.1 1808146 1808463 R Operon 862 Gene 4 COG0526 Thiol-disulfide isomerase and thioredoxins; thiol-disulfide isomerase and thioredoxin complement(1808146..1808463) Streptococcus pneumoniae AP200 9727946 YP_003877498.1 CDS SPAP_1933 NC_014494.1 1808460 1808729 R Operon 862 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(1808460..1808729) Streptococcus pneumoniae AP200 9727947 YP_003877499.1 CDS SPAP_1934 NC_014494.1 1809044 1809259 R Operon 863 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1809044..1809259) Streptococcus pneumoniae AP200 9727948 YP_003877500.1 CDS SPAP_1935 NC_014494.1 1809396 1810070 R Operon 864 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1809396..1810070) Streptococcus pneumoniae AP200 9727949 YP_003877501.1 CDS SPAP_1936 NC_014494.1 1810076 1810522 R Operon 864 Gene 2 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator complement(1810076..1810522) Streptococcus pneumoniae AP200 9727950 YP_003877502.1 CDS SPAP_1937 NC_014494.1 1810624 1811139 R Operon 865 Gene 1 COG0671 Membrane-associated phospholipid phosphatase; membrane-associated phospholipid phosphatase complement(1810624..1811139) Streptococcus pneumoniae AP200 9727951 YP_003877503.1 CDS SPAP_1938 NC_014494.1 1811136 1811498 R Operon 865 Gene 2 COG4898 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1811136..1811498) Streptococcus pneumoniae AP200 9727952 YP_003877504.1 CDS SPAP_1939 NC_014494.1 1811564 1812580 R Operon 866 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1811564..1812580) Streptococcus pneumoniae AP200 9727953 YP_003877505.1 CDS SPAP_1940 NC_014494.1 1812602 1813423 R Operon 866 Gene 2 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1812602..1813423) Streptococcus pneumoniae AP200 9727954 YP_003877506.1 CDS SPAP_1941 NC_014494.1 1813440 1813910 R Operon 866 Gene 3 COG1846 Transcriptional regulators; transcriptional regulator complement(1813440..1813910) Streptococcus pneumoniae AP200 9727955 YP_003877507.1 CDS SPAP_1942 NC_014494.1 1814034 1814750 R Operon 867 Gene 1 COG0217 Uncharacterized conserved protein; hypothetical protein complement(1814034..1814750) Streptococcus pneumoniae AP200 9727956 YP_003877508.1 CDS SPAP_1943 NC_014494.1 1815631 1817046 R pneumolysin (thiol-activated cytolysin); hypothetical protein complement(1815631..1817046) Streptococcus pneumoniae AP200 9727957 YP_003877509.1 CDS SPAP_1944 NC_014494.1 1817057 1817467 R Operon 868 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1817057..1817467) Streptococcus pneumoniae AP200 9727958 YP_003877510.1 CDS SPAP_1945 NC_014494.1 1817460 1818068 R Operon 868 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1817460..1818068) Streptococcus pneumoniae AP200 9727959 YP_003877511.1 CDS SPAP_1946 NC_014494.1 1818081 1818539 R Operon 868 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1818081..1818539) Streptococcus pneumoniae AP200 9727960 YP_003877512.1 CDS SPAP_1947 NC_014494.1 1818664 1818795 D Operon 869 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1818664..1818795 Streptococcus pneumoniae AP200 9727961 YP_003877513.1 CDS SPAP_1948 NC_014494.1 1818800 1819063 D transposase-like protein, IS1381 ISSpn7 1818800..1819063 Streptococcus pneumoniae AP200 9727962 YP_003877514.1 CDS SPAP_1949 NC_014494.1 1819827 1820087 R Operon 870 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1819827..1820087) Streptococcus pneumoniae AP200 9727963 YP_003877515.1 CDS SPAP_1950 NC_014494.1 1820146 1820697 R Operon 870 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1820146..1820697) Streptococcus pneumoniae AP200 9727964 YP_003877516.1 CDS SPAP_1951 NC_014494.1 1820687 1820884 R Operon 870 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1820687..1820884) Streptococcus pneumoniae AP200 9727965 YP_003877517.1 CDS SPAP_1952 NC_014494.1 1820903 1821682 R Operon 870 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1820903..1821682) Streptococcus pneumoniae AP200 9727966 YP_003877518.1 CDS SPAP_1953 NC_014494.1 1822090 1822515 R Operon 871 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1822090..1822515) Streptococcus pneumoniae AP200 9727967 YP_003877519.1 CDS SPAP_1954 NC_014494.1 1822644 1822892 R Operon 872 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1822644..1822892) Streptococcus pneumoniae AP200 9727968 YP_003877520.1 CDS SPAP_1955 NC_014494.1 1823049 1823255 R Operon 873 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1823049..1823255) Streptococcus pneumoniae AP200 9727969 YP_003877521.1 CDS SPAP_1956 NC_014494.1 1823242 1823403 R Operon 873 Gene 2 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1823242..1823403) Streptococcus pneumoniae AP200 9727970 YP_003877522.1 CDS SPAP_1957 NC_014494.1 1823762 1824718 R Operon 874 Gene 1 COG5263 FOG: Glucan-binding domain (YG repeat); glucan-binding domain-containing protein complement(1823762..1824718) Streptococcus pneumoniae AP200 9727971 YP_003877523.1 CDS SPAP_1958 NC_014494.1 1825094 1826464 R Operon 875 Gene 1 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump complement(1825094..1826464) Streptococcus pneumoniae AP200 9727972 YP_003877524.1 CDS SPAP_1959 NC_014494.1 1826771 1827937 R Operon 876 Gene 1 COG0468 RecA/RadA recombinase; recombinase A complement(1826771..1827937) Streptococcus pneumoniae AP200 9727973 YP_003877525.1 CDS SPAP_1960 NC_014494.1 1827992 1829248 R Operon 876 Gene 2 COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; putative nucleotide-utilizing enzyme complement(1827992..1829248) Streptococcus pneumoniae AP200 9727974 YP_003877526.1 CDS SPAP_1961 NC_014494.1 1829333 1830349 R Operon 877 Gene 1 COG1316 Transcriptional regulator; transcriptional regulator complement(1829333..1830349) Streptococcus pneumoniae AP200 9727975 YP_003877527.1 CDS SPAP_1962 NC_014494.1 1830357 1830875 R Operon 877 Gene 2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; histone acetyltransferase HPA2-like acetyltransferase complement(1830357..1830875) Streptococcus pneumoniae AP200 9727976 YP_003877528.1 CDS SPAP_1963 NC_014494.1 1830865 1831308 R Operon 877 Gene 3 COG0802 Predicted ATPase or kinase; putative ATPase complement(1830865..1831308) Streptococcus pneumoniae AP200 9727977 YP_003877529.1 CDS SPAP_1964 NC_014494.1 1831394 1832014 R Operon 877 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1831394..1832014) Streptococcus pneumoniae AP200 9727978 YP_003877530.1 CDS SPAP_1965 NC_014494.1 1832397 1833260 R Operon 878 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1832397..1833260) Streptococcus pneumoniae AP200 9727979 YP_003877531.1 CDS SPAP_1966 NC_014494.1 1833606 1835621 D Operon 879 Gene 1 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein 1833606..1835621 Streptococcus pneumoniae AP200 9727980 YP_003877532.1 CDS SPAP_1967 NC_014494.1 1835623 1836255 D Operon 879 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase 1835623..1836255 Streptococcus pneumoniae AP200 9727981 YP_003877533.1 CDS SPAP_1968 NC_014494.1 1836396 1836674 D Operon 880 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1836396..1836674 Streptococcus pneumoniae AP200 9727982 YP_003877534.1 CDS SPAP_1969 NC_014494.1 1837184 1837597 R Operon 881 Gene 1 COG0105 Nucleoside diphosphate kinase; nucleoside diphosphate kinase complement(1837184..1837597) Streptococcus pneumoniae AP200 9727983 YP_003877535.1 CDS SPAP_1970 NC_014494.1 1837708 1841385 R Operon 882 Gene 1 COG0086 DNA-directed RNA polymerase, beta' subunit/160 kD subunit; DNA-directed RNA polymerase subunits beta'/160 kD subunit complement(1837708..1841385) Streptococcus pneumoniae AP200 9727984 YP_003877536.1 CDS SPAP_1971 NC_014494.1 1841418 1845029 R Operon 882 Gene 2 COG0085 DNA-directed RNA polymerase, beta subunit/140 kD subunit; DNA-directed RNA polymerase subunit beta/140 kD subunit complement(1841418..1845029) Streptococcus pneumoniae AP200 9727985 YP_003877537.1 CDS SPAP_1973 NC_014494.1 1845713 1847044 R Operon 883 Gene 1 COG1253 Hemolysins and related proteins containing CBS domains; hemolysins-like protein complement(1845713..1847044) Streptococcus pneumoniae AP200 9727987 YP_003877538.1 CDS SPAP_1974 NC_014494.1 1847335 1848159 R Operon 884 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1847335..1848159) Streptococcus pneumoniae AP200 9727988 YP_003877539.1 CDS SPAP_1975 NC_014494.1 1848198 1848392 R Operon 884 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1848198..1848392) Streptococcus pneumoniae AP200 9727989 YP_003877540.1 CDS SPAP_1976 NC_014494.1 1848379 1849662 R Operon 884 Gene 3 COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; UDP-N-acetylglucosamine enolpyruvyl transferase complement(1848379..1849662) Streptococcus pneumoniae AP200 9727990 YP_003877541.1 CDS SPAP_1977 NC_014494.1 1849686 1849916 R Operon 884 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1849686..1849916) Streptococcus pneumoniae AP200 9727991 YP_003877542.1 CDS SPAP_1978 NC_014494.1 1849974 1851011 R Operon 884 Gene 5 COG3480 Predicted secreted protein containing a PDZ domain; hypothetical protein complement(1849974..1851011) Streptococcus pneumoniae AP200 9727992 YP_003877543.1 CDS SPAP_1979 NC_014494.1 1850995 1851306 R Operon 884 Gene 6 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase complement(1850995..1851306) Streptococcus pneumoniae AP200 9727993 YP_003877544.1 CDS SPAP_1980 NC_014494.1 1851315 1851482 R Operon 884 Gene 7 COG0669 Phosphopantetheine adenylyltransferase; phosphopantetheine adenylyltransferase complement(1851315..1851482) Streptococcus pneumoniae AP200 9727994 YP_003877545.1 CDS SPAP_1981 NC_014494.1 1851472 1852011 R Operon 884 Gene 8 COG0742 N6-adenine-specific methylase; N6-adenine-specific methylase complement(1851472..1852011) Streptococcus pneumoniae AP200 9727995 YP_003877546.1 CDS SPAP_1982 NC_014494.1 1852076 1853068 R Operon 884 Gene 9 COG2502 Asparagine synthetase A; asparagine synthetase A complement(1852076..1853068) Streptococcus pneumoniae AP200 9727996 YP_003877547.1 CDS SPAP_1983 NC_014494.1 1853179 1853862 R Operon 885 Gene 1 COG0670 Integral membrane protein, interacts with FtsH; integral membrane protein complement(1853179..1853862) Streptococcus pneumoniae AP200 9727997 YP_003877548.1 CDS SPAP_1984 NC_014494.1 1853918 1854658 R Operon 885 Gene 2 COG0566 rRNA methylases; rRNA methylase complement(1853918..1854658) Streptococcus pneumoniae AP200 9727998 YP_003877549.1 CDS SPAP_1985 NC_014494.1 1854692 1854970 D Operon 886 Gene 1 COG1254 Acylphosphatases; acylphosphatase 1854692..1854970 Streptococcus pneumoniae AP200 9727999 YP_003877550.1 CDS SPAP_1986 NC_014494.1 1855048 1855974 D Operon 886 Gene 2 COG0706 Preprotein translocase subunit YidC; preprotein translocase subunit YidC 1855048..1855974 Streptococcus pneumoniae AP200 9728000 YP_003877551.1 CDS SPAP_1987 NC_014494.1 1856049 1856843 R Operon 887 Gene 1 COG1180 Pyruvate-formate lyase-activating enzyme; pyruvate-formate lyase-activating enzyme complement(1856049..1856843) Streptococcus pneumoniae AP200 9728001 YP_003877552.1 CDS SPAP_1988 NC_014494.1 1856969 1858219 R Operon 888 Gene 1 COG0019 Diaminopimelate decarboxylase; diaminopimelate decarboxylase complement(1856969..1858219) Streptococcus pneumoniae AP200 9728002 YP_003877553.1 CDS SPAP_1989 NC_014494.1 1858286 1859113 R Operon 888 Gene 2 COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins; adenine/guanine phosphoribosyltransferases-like PRPP-binding protein complement(1858286..1859113) Streptococcus pneumoniae AP200 9728003 YP_003877554.1 CDS SPAP_1990 NC_014494.1 1859380 1860321 R Operon 889 Gene 1 COG3481 Predicted HD-superfamily hydrolase; putative HD superfamily hydrolase complement(1859380..1860321) Streptococcus pneumoniae AP200 9728004 YP_003877555.1 CDS SPAP_1991 NC_014494.1 1860311 1861567 R Operon 889 Gene 2 COG1322 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1860311..1861567) Streptococcus pneumoniae AP200 9728005 YP_003877556.1 CDS SPAP_1992 NC_014494.1 1861569 1862231 R Operon 889 Gene 3 COG1564 Thiamine pyrophosphokinase; thiamine pyrophosphokinase complement(1861569..1862231) Streptococcus pneumoniae AP200 9728006 YP_003877557.1 CDS SPAP_1993 NC_014494.1 1862194 1862850 R Operon 889 Gene 4 COG0036 Pentose-5-phosphate-3-epimerase; pentose-5-phosphate-3-epimerase complement(1862194..1862850) Streptococcus pneumoniae AP200 9728007 YP_003877558.1 CDS SPAP_1994 NC_014494.1 1862861 1863739 R Operon 889 Gene 5 COG1162 Predicted GTPases; putative GTPase complement(1862861..1863739) Streptococcus pneumoniae AP200 9728008 YP_003877559.1 CDS SPAP_1995 NC_014494.1 1863741 1864613 R Operon 889 Gene 6 COG0030 Dimethyladenosine transferase (rRNA methylation); dimethyladenosine transferase complement(1863741..1864613) Streptococcus pneumoniae AP200 9728009 YP_003877560.1 CDS SPAP_1996 NC_014494.1 1864744 1865052 R Operon 890 Gene 1 protein supported gi|111658872|ref|ZP_01409493.1| hypothetical protein SpneT_02000043; hypothetical protein complement(1864744..1865052) Streptococcus pneumoniae AP200 9728010 YP_003877561.1 CDS SPAP_1997 NC_014494.1 1865045 1865686 R Operon 890 Gene 2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component; antimicrobial peptide ABC transporter ATPase complement(1865045..1865686) Streptococcus pneumoniae AP200 9728011 YP_003877562.1 CDS SPAP_1998 NC_014494.1 1865688 1867718 R Operon 890 Gene 3 COG4652 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1865688..1867718) Streptococcus pneumoniae AP200 9728012 YP_003877563.1 CDS SPAP_1999 NC_014494.1 1867795 1868091 R Operon 890 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1867795..1868091) Streptococcus pneumoniae AP200 9728013 YP_003877564.1 CDS SPAP_2000 NC_014494.1 1868564 1868938 R Operon 891 Gene 1 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 complement(1868564..1868938) Streptococcus pneumoniae AP200 9728014 YP_003877565.1 CDS SPAP_2001 NC_014494.1 1868950 1870197 R transposase-like protein, IS1515 complement(1868950..1870197) Streptococcus pneumoniae AP200 9728015 YP_003877566.1 CDS SPAP_2002 NC_014494.1 1870269 1870829 R Operon 891 Gene 3 COG1658 Small primase-like proteins (Toprim domain); small primase-like protein complement(1870269..1870829) Streptococcus pneumoniae AP200 9728016 YP_003877567.1 CDS SPAP_2003 NC_014494.1 1870829 1871602 R Operon 891 Gene 4 COG0084 Mg-dependent DNase; Mg-dependent DNase complement(1870829..1871602) Streptococcus pneumoniae AP200 9728017 YP_003877568.1 CDS SPAP_2004 NC_014494.1 1871907 1872572 R cell wall surface anchor family protein; hypothetical protein complement(1871907..1872572) Streptococcus pneumoniae AP200 9728018 YP_003877569.1 CDS SPAP_2005 NC_014494.1 1872835 1872969 R Operon 893 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1872835..1872969) Streptococcus pneumoniae AP200 9728019 YP_003877570.1 CDS SPAP_2006 NC_014494.1 1873114 1874328 R Operon 894 Gene 1 COG0436 Aspartate/tyrosine/aromatic aminotransferase; aspartate/tyrosine/aromatic aminotransferase complement(1873114..1874328) Streptococcus pneumoniae AP200 9728020 YP_003877571.1 CDS SPAP_2007 NC_014494.1 1874484 1874774 R Operon 894 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1874484..1874774) Streptococcus pneumoniae AP200 9728021 YP_003877572.1 CDS SPAP_2008 NC_014494.1 1874939 1875391 D Operon 895 Gene 1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins; Universal stress protein UspA-like nucleotide-binding protein 1874939..1875391 Streptococcus pneumoniae AP200 9728022 YP_003877573.1 CDS SPAP_2009 NC_014494.1 1875426 1876814 R Operon 896 Gene 1 COG0561 Predicted hydrolases of the HAD superfamily; putative HAD superfamily hydrolase complement(1875426..1876814) Streptococcus pneumoniae AP200 9728023 YP_003877574.1 CDS SPAP_2010 NC_014494.1 1876880 1877842 D Operon 897 Gene 1 COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D 1876880..1877842 Streptococcus pneumoniae AP200 9728024 YP_003877575.1 CDS SPAP_2011 NC_014494.1 1878138 1879148 R Operon 898 Gene 1 COG1609 Transcriptional regulators; transcriptional regulator complement(1878138..1879148) Streptococcus pneumoniae AP200 9728025 YP_003877576.1 CDS SPAP_2012 NC_014494.1 1879573 1880172 R Operon 899 Gene 1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; CheY-like receiver/HTH DNA-binding domain-containing response regulator complement(1879573..1880172) Streptococcus pneumoniae AP200 9728026 YP_003877577.1 CDS SPAP_2013 NC_014494.1 1880174 1881241 R Operon 899 Gene 2 COG4585 Signal transduction histidine kinase; signal transduction histidine kinase complement(1880174..1881241) Streptococcus pneumoniae AP200 9728027 YP_003877578.1 CDS SPAP_2014 NC_014494.1 1881271 1882008 R Operon 899 Gene 3 COG0842 ABC-type multidrug transport system, permease component; multidrug ABC transporter permease complement(1881271..1882008) Streptococcus pneumoniae AP200 9728028 YP_003877579.1 CDS SPAP_2015 NC_014494.1 1882010 1882894 R Operon 899 Gene 4 COG1131 ABC-type multidrug transport system, ATPase component; multidrug ABC transporter ATPase complement(1882010..1882894) Streptococcus pneumoniae AP200 9728029 YP_003877580.1 CDS SPAP_2016 NC_014494.1 1882881 1883075 R Operon 899 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(1882881..1883075) Streptococcus pneumoniae AP200 9728030 YP_003877581.1 CDS SPAP_2017 NC_014494.1 1883072 1883251 R Operon 899 Gene 6 Putative gene predicted by FgenesB; hypothetical protein complement(1883072..1883251) Streptococcus pneumoniae AP200 9728031 YP_003877582.1 CDS SPAP_2031 NC_014494.1 1889968 1890345 R transposase-like protein, IS1239 complement(1889968..1890345) Streptococcus pneumoniae AP200 9728045 YP_003877583.1 CDS SPAP_2032 NC_014494.1 1890381 1890923 R transposase-like protein, IS1239 complement(1890381..1890923) Streptococcus pneumoniae AP200 9728046 YP_003877584.1 CDS SPAP_2033 NC_014494.1 1891211 1891690 R Operon 901 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1891211..1891690) Streptococcus pneumoniae AP200 9728047 YP_003877585.1 CDS SPAP_2034 NC_014494.1 1891812 1892348 R Operon 902 Gene 1 COG0250 Transcription antiterminator; transcription antiterminator complement(1891812..1892348) Streptococcus pneumoniae AP200 9728048 YP_003877586.1 CDS SPAP_2035 NC_014494.1 1892403 1892579 R Operon 902 Gene 2 COG0690 Preprotein translocase subunit SecE; preprotein translocase subunit SecE complement(1892403..1892579) Streptococcus pneumoniae AP200 9728049 YP_003877587.1 CDS SPAP_2036 NC_014494.1 1892491 1892691 D Operon 903 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1892491..1892691 Streptococcus pneumoniae AP200 9728050 YP_003877588.1 CDS SPAP_2037 NC_014494.1 1892589 1892741 R Operon 904 Gene 1 protein supported gi|15903864|ref|NP_359414.1| 50S ribosomal protein L33; hypothetical protein complement(1892589..1892741) Streptococcus pneumoniae AP200 9728051 YP_003877589.1 CDS SPAP_2038 NC_014494.1 1892794 1894989 R Operon 904 Gene 2 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase complement(1892794..1894989) Streptococcus pneumoniae AP200 9728052 YP_003877590.1 CDS SPAP_2039 NC_014494.1 1895076 1895951 D Operon 905 Gene 1 COG0564 Pseudouridylate synthases, 23S RNA-specific; 23S RNA-specific pseudouridylate synthase 1895076..1895951 Streptococcus pneumoniae AP200 9728053 YP_003877591.1 CDS SPAP_2040 NC_014494.1 1896018 1897025 R Operon 906 Gene 1 COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(1896018..1897025) Streptococcus pneumoniae AP200 9728054 YP_003877592.1 CDS SPAP_2041 NC_014494.1 1897202 1898164 R Operon 907 Gene 1 COG0577 ABC-type antimicrobial peptide transport system, permease component; antimicrobial peptide ABC transporter permease complement(1897202..1898164) Streptococcus pneumoniae AP200 9728055 YP_003877593.1 CDS SPAP_2042 NC_014494.1 1898225 1898407 R Operon 907 Gene 2 COG3335 Transposase and inactivated derivatives; transposase-like protein, IS630 complement(1898225..1898407) Streptococcus pneumoniae AP200 9728056 YP_003877594.1 CDS SPAP_2043 NC_014494.1 1898723 1899088 R transposase-like protein, IS630 complement(1898723..1899088) Streptococcus pneumoniae AP200 9728057 YP_003877595.1 CDS SPAP_2044 NC_014494.1 1899201 1900073 R Operon 909 Gene 1 COG0157 Nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase complement(1899201..1900073) Streptococcus pneumoniae AP200 9728058 YP_003877596.1 CDS SPAP_2045 NC_014494.1 1900310 1901620 D Operon 910 Gene 1 COG0471 Di- and tricarboxylate transporters; di- and tricarboxylate transporter 1900310..1901620 Streptococcus pneumoniae AP200 9728059 YP_003877597.1 CDS SPAP_2046 NC_014494.1 1901991 1902185 R Operon 911 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1901991..1902185) Streptococcus pneumoniae AP200 9728060 YP_003877598.1 CDS SPAP_2047 NC_014494.1 1902645 1903373 R Operon 912 Gene 1 COG2188 Transcriptional regulators; transcriptional regulator complement(1902645..1903373) Streptococcus pneumoniae AP200 9728061 YP_003877599.1 CDS SPAP_2048 NC_014494.1 1903531 1904940 D Operon 913 Gene 1 COG2723 Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase; beta-glucosidase/6-phospho-beta-glucosidase/ beta- galactosidase 1903531..1904940 Streptococcus pneumoniae AP200 9728062 YP_003877600.1 CDS SPAP_2049 NC_014494.1 1904958 1906253 D Operon 913 Gene 2 COG1455 Phosphotransferase system cellobiose-specific component IIC; PTS system cellobiose-specific transporter subunit IIC 1904958..1906253 Streptococcus pneumoniae AP200 9728063 YP_003877601.1 CDS SPAP_2050 NC_014494.1 1906258 1906566 D Operon 913 Gene 3 COG1440 Phosphotransferase system cellobiose-specific component IIB; PTS system cellobiose-specific transporter subunit IIB 1906258..1906566 Streptococcus pneumoniae AP200 9728064 YP_003877602.1 CDS SPAP_2051 NC_014494.1 1906563 1906871 D Operon 913 Gene 4 COG1447 Phosphotransferase system cellobiose-specific component IIA; PTS system cellobiose-specific transporter subunit IIA 1906563..1906871 Streptococcus pneumoniae AP200 9728065 YP_003877603.1 CDS SPAP_2052 NC_014494.1 1907738 1910410 R Operon 914 Gene 1 COG1012 NAD-dependent aldehyde dehydrogenases; NAD-dependent aldehyde dehydrogenase complement(1907738..1910410) Streptococcus pneumoniae AP200 9728066 YP_003877604.1 CDS SPAP_2053 NC_014494.1 1910689 1911099 R Operon 915 Gene 1 COG4642 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1910689..1911099) Streptococcus pneumoniae AP200 9728067 YP_003877605.1 CDS SPAP_2054 NC_014494.1 1911101 1911529 R Operon 915 Gene 2 COG0394 Protein-tyrosine-phosphatase; protein-tyrosine-phosphatase complement(1911101..1911529) Streptococcus pneumoniae AP200 9728068 YP_003877606.1 CDS SPAP_2055 NC_014494.1 1911575 1911874 R Operon 915 Gene 3 COG1862 Preprotein translocase subunit YajC; preprotein translocase subunit YajC complement(1911575..1911874) Streptococcus pneumoniae AP200 9728069 YP_003877607.1 CDS SPAP_2056 NC_014494.1 1911991 1913967 R Operon 916 Gene 1 COG0021 Transketolase; transketolase complement(1911991..1913967) Streptococcus pneumoniae AP200 9728070 YP_003877608.1 CDS SPAP_2057 NC_014494.1 1914080 1915171 R Operon 917 Gene 1 COG2220 Predicted Zn-dependent hydrolases of the beta-lactamase fold; putative Zn-dependent hydrolase complement(1914080..1915171) Streptococcus pneumoniae AP200 9728071 YP_003877609.1 CDS SPAP_2058 NC_014494.1 1915283 1916956 R Operon 918 Gene 1 COG3711 Transcriptional antiterminator; transcriptional antiterminator complement(1915283..1916956) Streptococcus pneumoniae AP200 9728072 YP_003877610.1 CDS SPAP_2059 NC_014494.1 1917135 1917839 R Operon 919 Gene 1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; ribulose-5-phosphate 4-epimerase-like epimerase and aldolase complement(1917135..1917839) Streptococcus pneumoniae AP200 9728073 YP_003877611.1 CDS SPAP_2060 NC_014494.1 1917841 1918704 R Operon 919 Gene 2 COG3623 Putative L-xylulose-5-phosphate 3-epimerase; putative L-xylulose-5-phosphate 3-epimerase complement(1917841..1918704) Streptococcus pneumoniae AP200 9728074 YP_003877612.1 CDS SPAP_2061 NC_014494.1 1918708 1919373 R Operon 919 Gene 3 COG0269 3-hexulose-6-phosphate synthase and related proteins; 3-hexulose-6-phosphate synthase-like protein complement(1918708..1919373) Streptococcus pneumoniae AP200 9728075 YP_003877613.1 CDS SPAP_2062 NC_014494.1 1919390 1919875 R Operon 919 Gene 4 COG1762 Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); PTS system mannitol/fructose-specific transporter subunit IIA domain-containing protein complement(1919390..1919875) Streptococcus pneumoniae AP200 9728076 YP_003877614.1 CDS SPAP_2063 NC_014494.1 1919952 1920233 R Operon 919 Gene 5 COG3414 Phosphotransferase system, galactitol-specific IIB component; PTS system galactitol-specific transporter subunit IIB complement(1919952..1920233) Streptococcus pneumoniae AP200 9728077 YP_003877615.1 CDS SPAP_2064 NC_014494.1 1920256 1921713 R Operon 919 Gene 6 COG3037 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1920256..1921713) Streptococcus pneumoniae AP200 9728078 YP_003877616.1 CDS SPAP_2065 NC_014494.1 1921844 1922467 R Operon 920 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1921844..1922467) Streptococcus pneumoniae AP200 9728079 YP_003877617.1 CDS SPAP_2066 NC_014494.1 1922518 1923504 R Operon 920 Gene 2 COG1847 Predicted RNA-binding protein; putative RNA-binding protein complement(1922518..1923504) Streptococcus pneumoniae AP200 9728080 YP_003877618.1 CDS SPAP_2067 NC_014494.1 1923523 1924329 R Operon 920 Gene 3 COG0706 Preprotein translocase subunit YidC; preprotein translocase subunit YidC complement(1923523..1924329) Streptococcus pneumoniae AP200 9728081 YP_003877619.1 CDS SPAP_2068 NC_014494.1 1924322 1924693 R Operon 920 Gene 4 COG0594 RNase P protein component; RNase P protein component complement(1924322..1924693) Streptococcus pneumoniae AP200 9728082 YP_003877620.1 CDS SPAP_2069 NC_014494.1 1924842 1926032 R Operon 921 Gene 1 COG0282 Acetate kinase; acetate kinase complement(1924842..1926032) Streptococcus pneumoniae AP200 9728083 YP_003877621.1 CDS SPAP_2070 NC_014494.1 1926083 1927036 R Operon 921 Gene 2 COG0827 Adenine-specific DNA methylase; adenine-specific DNa methylase complement(1926083..1927036) Streptococcus pneumoniae AP200 9728084 YP_003877622.1 CDS SPAP_2071 NC_014494.1 1927097 1927477 R Operon 921 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(1927097..1927477) Streptococcus pneumoniae AP200 9728085 YP_003877623.1 CDS SPAP_2072 NC_014494.1 1927509 1927691 R Operon 921 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(1927509..1927691) Streptococcus pneumoniae AP200 9728086 YP_003877624.1 CDS SPAP_2073 NC_014494.1 1927828 1928241 R Operon 922 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1927828..1928241) Streptococcus pneumoniae AP200 9728087 YP_003877625.1 CDS SPAP_2074 NC_014494.1 1928219 1928680 R Operon 922 Gene 2 COG4940 Competence protein ComGF; competence protein ComGF complement(1928219..1928680) Streptococcus pneumoniae AP200 9728088 YP_003877626.1 CDS SPAP_2075 NC_014494.1 1928643 1928945 R Operon 922 Gene 3 COG2165 Type II secretory pathway, pseudopilin PulG; type II secretory pathway, pseudopilin PulG complement(1928643..1928945) Streptococcus pneumoniae AP200 9728089 YP_003877627.1 CDS SPAP_2076 NC_014494.1 1928908 1929336 R Operon 922 Gene 4 COG2165 Type II secretory pathway, pseudopilin PulG; type II secretory pathway, pseudopilin PulG complement(1928908..1929336) Streptococcus pneumoniae AP200 9728090 YP_003877628.1 CDS SPAP_2077 NC_014494.1 1929305 1929631 R Operon 922 Gene 5 COG4537 Competence protein ComGC; competence protein ComGC complement(1929305..1929631) Streptococcus pneumoniae AP200 9728091 YP_003877629.1 CDS SPAP_2078 NC_014494.1 1929633 1930505 R Operon 922 Gene 6 COG1459 Type II secretory pathway, component PulF; type II secretory pathway, component PulF complement(1929633..1930505) Streptococcus pneumoniae AP200 9728092 YP_003877630.1 CDS SPAP_2079 NC_014494.1 1930597 1931538 R Operon 922 Gene 7 COG2804 Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; type II secretory pathway, ATPase PulE/tfp pilus assembly pathway ATPase PilB complement(1930597..1931538) Streptococcus pneumoniae AP200 9728093 YP_003877631.1 CDS SPAP_2080 NC_014494.1 1931614 1931799 R Operon 922 Gene 8 COG4699 Uncharacterized protein conserved in bacteria; hypothetical protein complement(1931614..1931799) Streptococcus pneumoniae AP200 9728094 YP_003877632.1 CDS SPAP_2081 NC_014494.1 1932130 1933188 R Operon 923 Gene 1 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases; threonine dehydrogenase-like Zn-dependent dehydrogenase complement(1932130..1933188) Streptococcus pneumoniae AP200 9728095 YP_003877633.1 CDS SPAP_2082 NC_014494.1 1933351 1934502 R Operon 924 Gene 1 COG1820 N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase complement(1933351..1934502) Streptococcus pneumoniae AP200 9728096 YP_003877634.1 CDS SPAP_2083 NC_014494.1 1934655 1936472 R Operon 925 Gene 1 COG1835 Predicted acyltransferases; putative acyltransferase complement(1934655..1936472) Streptococcus pneumoniae AP200 9728097 YP_003877635.1 CDS SPAP_2084 NC_014494.1 1936573 1937715 R Operon 926 Gene 1 COG0343 Queuine/archaeosine tRNA-ribosyltransferase; Queuine/archaeosine tRNA-ribosyltransferase complement(1936573..1937715) Streptococcus pneumoniae AP200 9728098 YP_003877636.1 CDS SPAP_2085 NC_014494.1 1937845 1938702 D Operon 927 Gene 1 COG5523 Predicted integral membrane protein; putative integral membrane protein 1937845..1938702 Streptococcus pneumoniae AP200 9728099 YP_003877637.1 CDS SPAP_2086 NC_014494.1 1938730 1939374 R Operon 928 Gene 1 COG2039; N-terminal pyroglutamyl peptidase; pyrrolidone-carboxylate peptidase complement(1938730..1939374) Streptococcus pneumoniae AP200 9728100 YP_003877638.1 CDS SPAP_2087 NC_014494.1 1939449 1939850 R Operon 928 Gene 2 COG3759 Predicted membrane protein; hypothetical protein complement(1939449..1939850) Streptococcus pneumoniae AP200 9728101 YP_003877639.1 CDS SPAP_2088 NC_014494.1 1939861 1940286 R Operon 928 Gene 3 COG1846 Transcriptional regulators; transcriptional regulator complement(1939861..1940286) Streptococcus pneumoniae AP200 9728102 YP_003877640.1 CDS SPAP_2089 NC_014494.1 1940609 1941721 R Operon 929 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1940609..1941721) Streptococcus pneumoniae AP200 9728103 YP_003877641.1 CDS SPAP_2090 NC_014494.1 1941887 1942507 R Operon 930 Gene 1 COG0546 Predicted phosphatases; putative phosphatase complement(1941887..1942507) Streptococcus pneumoniae AP200 9728104 YP_003877642.1 CDS SPAP_2091 NC_014494.1 1942511 1943791 R Operon 930 Gene 2 COG0534 Na+-driven multidrug efflux pump; Na+-driven multidrug efflux pump complement(1942511..1943791) Streptococcus pneumoniae AP200 9728105 YP_003877643.1 CDS SPAP_2092 NC_014494.1 1943852 1945336 R Operon 931 Gene 1 COG0498 Threonine synthase; threonine synthase complement(1943852..1945336) Streptococcus pneumoniae AP200 9728106 YP_003877644.1 CDS SPAP_2093 NC_014494.1 1945412 1945945 R Operon 931 Gene 2 COG3572 Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase complement(1945412..1945945) Streptococcus pneumoniae AP200 9728107 YP_003877645.1 CDS SPAP_2094 NC_014494.1 1945919 1946344 D transposase-like protein, IS1515 1945919..1946344 Streptococcus pneumoniae AP200 9728108 YP_003877646.1 CDS SPAP_2095 NC_014494.1 1946356 1946733 D Operon 932 Gene 2 COG3293 Transposase and inactivated derivatives; transposase-like protein, IS1515 1946356..1946733 Streptococcus pneumoniae AP200 9728109 YP_003877647.1 CDS SPAP_2096 NC_014494.1 1946747 1947562 R Operon 933 Gene 1 COG3572 Gamma-glutamylcysteine synthetase; gamma-glutamylcysteine synthetase complement(1946747..1947562) Streptococcus pneumoniae AP200 9728110 YP_003877648.1 CDS SPAP_2115 NC_014494.1 1954033 1954467 R Operon 936 Gene 1 COG0295 Cytidine deaminase; cytidine deaminase complement(1954033..1954467) Streptococcus pneumoniae AP200 9728127 YP_003877649.1 CDS SPAP_2116 NC_014494.1 1954481 1955941 R Operon 936 Gene 2 COG0008 Glutamyl- and glutaminyl-tRNA synthetases; glutamyl- and glutaminyl-tRNA synthetase complement(1954481..1955941) Streptococcus pneumoniae AP200 9728128 YP_003877650.1 CDS SPAP_2117 NC_014494.1 1956065 1957414 R Operon 937 Gene 1 COG0166 Glucose-6-phosphate isomerase; glucose-6-phosphate isomerase complement(1956065..1957414) Streptococcus pneumoniae AP200 9728129 YP_003877651.1 CDS SPAP_2118 NC_014494.1 1957584 1958273 R Operon 938 Gene 1 COG2071 Predicted glutamine amidotransferases; putative glutamine amidotransferase complement(1957584..1958273) Streptococcus pneumoniae AP200 9728130 YP_003877652.1 CDS SPAP_2119 NC_014494.1 1958412 1960178 R Operon 939 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1958412..1960178) Streptococcus pneumoniae AP200 9728131 YP_003877653.1 CDS SPAP_2120 NC_014494.1 1960331 1960639 D Operon 940 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1960331..1960639 Streptococcus pneumoniae AP200 9728132 YP_003877654.1 CDS SPAP_2121 NC_014494.1 1960970 1962664 R Operon 941 Gene 1 COG1132 ABC-type multidrug transport system, ATPase and permease components; multidrug ABC transporter ATPase and permease complement(1960970..1962664) Streptococcus pneumoniae AP200 9728133 YP_003877655.1 CDS SPAP_2122 NC_014494.1 1962811 1965345 R Operon 942 Gene 1 COG0249 Mismatch repair ATPase (MutS family); mismatch repair ATPase complement(1962811..1965345) Streptococcus pneumoniae AP200 9728134 YP_003877656.1 CDS SPAP_2123 NC_014494.1 1965396 1965842 R Operon 942 Gene 2 COG1438 Arginine repressor; arginine repressor complement(1965396..1965842) Streptococcus pneumoniae AP200 9728135 YP_003877657.1 CDS SPAP_2124 NC_014494.1 1965978 1967669 D Operon 943 Gene 1 COG0018 Arginyl-tRNA synthetase; arginyl-tRNA synthetase 1965978..1967669 Streptococcus pneumoniae AP200 9728136 YP_003877658.1 CDS SPAP_2125 NC_014494.1 1967984 1968448 R transposase-like protein, IS1381 ISSpn7 complement(1967984..1968448) Streptococcus pneumoniae AP200 9728137 YP_003877659.1 CDS SPAP_2126 NC_014494.1 1968766 1969014 D Operon 945 Gene 1 COG3542 Uncharacterized conserved protein; hypothetical protein 1968766..1969014 Streptococcus pneumoniae AP200 9728138 YP_003877660.1 CDS SPAP_2127 NC_014494.1 1969098 1969352 D Operon 945 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1969098..1969352 Streptococcus pneumoniae AP200 9728139 YP_003877661.1 CDS SPAP_2128 NC_014494.1 1969375 1969806 D Operon 945 Gene 3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator 1969375..1969806 Streptococcus pneumoniae AP200 9728140 YP_003877662.1 CDS SPAP_2129 NC_014494.1 1969807 1971138 D Operon 945 Gene 4 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase 1969807..1971138 Streptococcus pneumoniae AP200 9728141 YP_003877663.1 CDS SPAP_2130 NC_014494.1 1971305 1972180 D Operon 945 Gene 5 COG0226 ABC-type phosphate transport system, periplasmic component; phosphate ABC transporter substrate-binding protein 1971305..1972180 Streptococcus pneumoniae AP200 9728142 YP_003877664.1 CDS SPAP_2131 NC_014494.1 1972346 1973161 D Operon 945 Gene 6 COG0573 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1972346..1973161 Streptococcus pneumoniae AP200 9728143 YP_003877665.1 CDS SPAP_2132 NC_014494.1 1973154 1973969 D Operon 945 Gene 7 COG0581 ABC-type phosphate transport system, permease component; phosphate ABC transporter permease 1973154..1973969 Streptococcus pneumoniae AP200 9728144 YP_003877666.1 CDS SPAP_2133 NC_014494.1 1973971 1974723 D Operon 945 Gene 8 COG1117 ABC-type phosphate transport system, ATPase component; phosphate ABC transporter ATPase 1973971..1974723 Streptococcus pneumoniae AP200 9728145 YP_003877667.1 CDS SPAP_2134 NC_014494.1 1974738 1975388 D Operon 945 Gene 9 COG0704 Phosphate uptake regulator; phosphate uptake regulator 1974738..1975388 Streptococcus pneumoniae AP200 9728146 YP_003877668.1 CDS SPAP_2135 NC_014494.1 1975456 1975881 D transposase-like protein, IS1380 ISSpn5 1975456..1975881 Streptococcus pneumoniae AP200 9728147 YP_003877669.1 CDS SPAP_2136 NC_014494.1 1976055 1976435 R Operon 947 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(1976055..1976435) Streptococcus pneumoniae AP200 9728148 YP_003877670.1 CDS SPAP_2137 NC_014494.1 1976647 1977663 D Operon 948 Gene 1 COG0240 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase 1976647..1977663 Streptococcus pneumoniae AP200 9728149 YP_003877671.1 CDS SPAP_2138 NC_014494.1 1977685 1978584 D Operon 948 Gene 2 COG1210 UDP-glucose pyrophosphorylase; UDP-glucose pyrophosphorylase 1977685..1978584 Streptococcus pneumoniae AP200 9728150 YP_003877672.1 CDS SPAP_2139 NC_014494.1 1978651 1979328 R Operon 949 Gene 1 COG0705 Uncharacterized membrane protein (homolog of Drosophila rhomboid); hypothetical protein complement(1978651..1979328) Streptococcus pneumoniae AP200 9728151 YP_003877673.1 CDS SPAP_2140 NC_014494.1 1979312 1979851 R Operon 949 Gene 2 COG0212 5-formyltetrahydrofolate cyclo-ligase; 5-formyltetrahydrofolate cyclo-ligase complement(1979312..1979851) Streptococcus pneumoniae AP200 9728152 YP_003877674.1 CDS SPAP_2141 NC_014494.1 1979863 1980993 R Operon 949 Gene 3 COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; metal-dependent amidase/aminoacylase/carboxypeptidase complement(1979863..1980993) Streptococcus pneumoniae AP200 9728153 YP_003877675.1 CDS SPAP_2142 NC_014494.1 1981061 1981759 R Operon 949 Gene 4 COG2171 Tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate N-succinyltransferase complement(1981061..1981759) Streptococcus pneumoniae AP200 9728154 YP_003877676.1 CDS SPAP_2143 NC_014494.1 1981989 1983104 R Operon 950 Gene 1 COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; drug/metabolite transporter (DMT) superfamily permease complement(1981989..1983104) Streptococcus pneumoniae AP200 9728155 YP_003877677.1 CDS SPAP_2144 NC_014494.1 1982965 1985430 R Operon 950 Gene 2 COG0744 Membrane carboxypeptidase (penicillin-binding protein); membrane carboxypeptidase complement(1982965..1985430) Streptococcus pneumoniae AP200 9728156 YP_003877678.1 CDS SPAP_2145 NC_014494.1 1985572 1986828 D Operon 951 Gene 1 COG0162 Tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 1985572..1986828 Streptococcus pneumoniae AP200 9728157 YP_003877679.1 CDS SPAP_2146 NC_014494.1 1986906 1988969 R Operon 952 Gene 1 COG2217 Cation transport ATPase; cation transport ATPase complement(1986906..1988969) Streptococcus pneumoniae AP200 9728158 YP_003877680.1 CDS SPAP_2147 NC_014494.1 1988971 1989249 R Operon 952 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(1988971..1989249) Streptococcus pneumoniae AP200 9728159 YP_003877681.1 CDS SPAP_2148 NC_014494.1 1989401 1990249 D Operon 953 Gene 1 COG0500 SAM-dependent methyltransferases; SAM-dependent methyltransferase 1989401..1990249 Streptococcus pneumoniae AP200 9728160 YP_003877682.1 CDS SPAP_2149 NC_014494.1 1990363 1990533 R Operon 954 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1990363..1990533) Streptococcus pneumoniae AP200 9728161 YP_003877683.1 CDS SPAP_2150 NC_014494.1 1990870 1991442 D Operon 955 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1990870..1991442 Streptococcus pneumoniae AP200 9728162 YP_003877684.1 CDS SPAP_2151 NC_014494.1 1991432 1991572 R Operon 956 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1991432..1991572) Streptococcus pneumoniae AP200 9728163 YP_003877685.1 CDS SPAP_2152 NC_014494.1 1991609 1991809 D Operon 957 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 1991609..1991809 Streptococcus pneumoniae AP200 9728164 YP_003877686.1 CDS SPAP_2153 NC_014494.1 1991983 1992129 R Operon 958 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(1991983..1992129) Streptococcus pneumoniae AP200 9728165 YP_003877687.1 CDS SPAP_2154 NC_014494.1 1992487 1994745 R Operon 959 Gene 1 COG0058 Glucan phosphorylase; glucan phosphorylase complement(1992487..1994745) Streptococcus pneumoniae AP200 9728166 YP_003877688.1 CDS SPAP_2155 NC_014494.1 1994771 1996288 R Operon 959 Gene 2 COG1640 4-alpha-glucanotransferase; 4-alpha-glucanotransferase complement(1994771..1996288) Streptococcus pneumoniae AP200 9728167 YP_003877689.1 CDS SPAP_2156 NC_014494.1 1996838 1998109 D Operon 960 Gene 1 COG2182 Maltose-binding periplasmic proteins/domains; maltose-binding periplasmic protein 1996838..1998109 Streptococcus pneumoniae AP200 9728168 YP_003877690.1 CDS SPAP_2157 NC_014494.1 1998205 1998948 D Operon 960 Gene 2 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1998205..1998948 Streptococcus pneumoniae AP200 9728169 YP_003877691.1 CDS SPAP_2158 NC_014494.1 1998960 1999511 D Operon 960 Gene 3 COG1175 ABC-type sugar transport systems, permease components; sugar ABC transporter permease 1998960..1999511 Streptococcus pneumoniae AP200 9728170 YP_003877692.1 CDS SPAP_2159 NC_014494.1 1999513 2000355 D Operon 960 Gene 4 COG3833 ABC-type maltose transport systems, permease component; maltose ABC transporter permease 1999513..2000355 Streptococcus pneumoniae AP200 9728171 YP_003877693.1 CDS SPAP_2160 NC_014494.1 2000608 2001408 D Operon 961 Gene 1 COG5521 Predicted integral membrane protein; putative integral membrane protein 2000608..2001408 Streptococcus pneumoniae AP200 9728172 YP_003877694.1 CDS SPAP_2161 NC_014494.1 2001418 2002404 D Operon 961 Gene 2 COG1609 Transcriptional regulators; transcriptional regulator 2001418..2002404 Streptococcus pneumoniae AP200 9728173 YP_003877695.1 CDS SPAP_2162 NC_014494.1 2002740 2003681 R Operon 962 Gene 1 COG1284 Uncharacterized conserved protein; hypothetical protein complement(2002740..2003681) Streptococcus pneumoniae AP200 9728174 YP_003877696.1 CDS SPAP_2163 NC_014494.1 2003659 2005422 R Operon 962 Gene 2 COG0173 Aspartyl-tRNA synthetase; aspartyl-tRNA synthetase complement(2003659..2005422) Streptococcus pneumoniae AP200 9728175 YP_003877697.1 CDS SPAP_2164 NC_014494.1 2005541 2005732 R Operon 963 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2005541..2005732) Streptococcus pneumoniae AP200 9728176 YP_003877698.1 CDS SPAP_2165 NC_014494.1 2005774 2006004 R Operon 963 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(2005774..2006004) Streptococcus pneumoniae AP200 9728177 YP_003877699.1 CDS SPAP_2166 NC_014494.1 2006022 2006663 R Operon 963 Gene 3 COG1266 Predicted metal-dependent membrane protease; putative metal-dependent membrane protease complement(2006022..2006663) Streptococcus pneumoniae AP200 9728178 YP_003877700.1 CDS SPAP_2167 NC_014494.1 2006675 2007409 R Operon 963 Gene 4 Putative gene predicted by FgenesB; hypothetical protein complement(2006675..2007409) Streptococcus pneumoniae AP200 9728179 YP_003877701.1 CDS SPAP_2168 NC_014494.1 2007412 2007609 R Operon 963 Gene 5 Putative gene predicted by FgenesB; hypothetical protein complement(2007412..2007609) Streptococcus pneumoniae AP200 9728180 YP_003877702.1 CDS SPAP_2169 NC_014494.1 2007609 2007815 R Operon 963 Gene 6 COG1476 Predicted transcriptional regulators; putative transcriptional regulator complement(2007609..2007815) Streptococcus pneumoniae AP200 9728181 YP_003877703.1 CDS SPAP_2170 NC_014494.1 2007825 2008139 R Operon 963 Gene 7 Putative gene predicted by FgenesB; hypothetical protein complement(2007825..2008139) Streptococcus pneumoniae AP200 9728182 YP_003877704.1 CDS SPAP_2171 NC_014494.1 2008435 2009724 R Operon 964 Gene 1 COG0124 Histidyl-tRNA synthetase; histidyl-tRNA synthetase complement(2008435..2009724) Streptococcus pneumoniae AP200 9728183 YP_003877705.1 CDS SPAP_2172 NC_014494.1 2009802 2011049 R Operon 964 Gene 2 protein supported gi|148990506|ref|ZP_01821647.1| ribosomal protein L11 methyltransferase; hypothetical protein complement(2009802..2011049) Streptococcus pneumoniae AP200 9728184 YP_003877706.1 CDS SPAP_2173 NC_014494.1 2011239 2012090 R Operon 965 Gene 1 COG1396 Predicted transcriptional regulators; putative transcriptional regulator complement(2011239..2012090) Streptococcus pneumoniae AP200 9728185 YP_003877707.1 CDS SPAP_2174 NC_014494.1 2012214 2012555 D Operon 966 Gene 1 COG2151 Predicted metal-sulfur cluster biosynthetic enzyme; putative metal-sulfur cluster biosynthetic enzyme 2012214..2012555 Streptococcus pneumoniae AP200 9728186 YP_003877708.1 CDS SPAP_2175 NC_014494.1 2012682 2012873 D Operon 967 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2012682..2012873 Streptococcus pneumoniae AP200 9728187 YP_003877709.1 CDS SPAP_2176 NC_014494.1 2012899 2014602 R Operon 968 Gene 1 COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; dihydroxyacid dehydratase/phosphogluconate dehydratase complement(2012899..2014602) Streptococcus pneumoniae AP200 9728188 YP_003877710.1 CDS SPAP_2177 NC_014494.1 2014835 2015764 R Operon 969 Gene 1 COG3958 Transketolase, C-terminal subunit; transketolase complement(2014835..2015764) Streptococcus pneumoniae AP200 9728189 YP_003877711.1 CDS SPAP_2178 NC_014494.1 2015764 2016621 R Operon 969 Gene 2 COG3959 Transketolase, N-terminal subunit; transketolase complement(2015764..2016621) Streptococcus pneumoniae AP200 9728190 YP_003877712.1 CDS SPAP_2179 NC_014494.1 2016625 2017971 R Operon 969 Gene 3 COG3037 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2016625..2017971) Streptococcus pneumoniae AP200 9728191 YP_003877713.1 CDS SPAP_2180 NC_014494.1 2017984 2018268 R Operon 969 Gene 4 protein supported gi|15901944|ref|NP_346548.1| PTS system, IIB component, putative; hypothetical protein complement(2017984..2018268) Streptococcus pneumoniae AP200 9728192 YP_003877714.1 CDS SPAP_2181 NC_014494.1 2018272 2020302 R Operon 969 Gene 5 COG3711 Transcriptional antiterminator; transcriptional antiterminator complement(2018272..2020302) Streptococcus pneumoniae AP200 9728193 YP_003877715.1 CDS SPAP_2182 NC_014494.1 2020493 2021500 D Operon 970 Gene 1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit 2020493..2021500 Streptococcus pneumoniae AP200 9728194 YP_003877716.1 CDS SPAP_2183 NC_014494.1 2021503 2021703 D Operon 970 Gene 2 COG4877 Uncharacterized protein conserved in bacteria; hypothetical protein 2021503..2021703 Streptococcus pneumoniae AP200 9728195 YP_003877717.1 CDS SPAP_2184 NC_014494.1 2021854 2022036 D Operon 971 Gene 1 protein supported gi|15901948|ref|NP_346552.1| 50S ribosomal protein L32; hypothetical protein 2021854..2022036 Streptococcus pneumoniae AP200 9728196 YP_003877718.1 CDS SPAP_2185 NC_014494.1 2022052 2022201 D Operon 971 Gene 2 protein supported gi|15901949|ref|NP_346553.1| 50S ribosomal protein L33; hypothetical protein 2022052..2022201 Streptococcus pneumoniae AP200 9728197 YP_003877719.1 CDS SPAP_2186 NC_014494.1 2022694 2024259 R Operon 972 Gene 1 COG5263 FOG: Choline binding protein PcpA; choline binding protein PcpA complement(2022694..2024259) Streptococcus pneumoniae AP200 9728198 YP_003877720.1 CDS SPAP_2187 NC_014494.1 2024594 2024776 D Operon 973 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2024594..2024776 Streptococcus pneumoniae AP200 9728199 YP_003877721.1 CDS SPAP_2188 NC_014494.1 2024721 2025107 D transposase-like protein, IS1381 ISSpn7 2024721..2025107 Streptococcus pneumoniae AP200 9728200 YP_003877722.1 CDS SPAP_2189 NC_014494.1 2025124 2025423 D transposase-like protein, IS1381 ISSpn7 2025124..2025423 Streptococcus pneumoniae AP200 9728201 YP_003877723.1 CDS SPAP_2190 NC_014494.1 2025495 2025821 R Operon 974 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2025495..2025821) Streptococcus pneumoniae AP200 9728202 YP_003877724.1 CDS SPAP_2191 NC_014494.1 2026148 2028028 R Operon 975 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2026148..2028028) Streptococcus pneumoniae AP200 9728203 YP_003877725.1 CDS SPAP_2192 NC_014494.1 2028022 2028891 R Operon 975 Gene 2 COG1940 Transcriptional regulator/sugar kinase; transcriptional regulator/sugar kinase complement(2028022..2028891) Streptococcus pneumoniae AP200 9728204 YP_003877726.1 CDS SPAP_2193 NC_014494.1 2028975 2031620 R Operon 975 Gene 3 COG0383 Alpha-mannosidase; alpha-mannosidase complement(2028975..2031620) Streptococcus pneumoniae AP200 9728205 YP_003877727.1 CDS SPAP_2194 NC_014494.1 2031711 2032991 R Operon 975 Gene 4 COG3538 Uncharacterized conserved protein; hypothetical protein complement(2031711..2032991) Streptococcus pneumoniae AP200 9728206 YP_003877728.1 CDS SPAP_2195 NC_014494.1 2033162 2035246 D Operon 976 Gene 1 COG3537 Putative alpha-1,2-mannosidase; putative alpha-1,2-mannosidase 2033162..2035246 Streptococcus pneumoniae AP200 9728207 YP_003877729.1 CDS SPAP_2196 NC_014494.1 2035286 2036965 R Operon 977 Gene 1 COG3669 Alpha-L-fucosidase; alpha-L-fucosidase complement(2035286..2036965) Streptococcus pneumoniae AP200 9728208 YP_003877730.1 CDS SPAP_2197 NC_014494.1 2037720 2038949 D Operon 978 Gene 1 protein supported gi|148984445|ref|ZP_01817733.1| 50S ribosomal protein L33; hypothetical protein 2037720..2038949 Streptococcus pneumoniae AP200 9728209 YP_003877731.1 CDS SPAP_2198 NC_014494.1 2039007 2040023 D Operon 978 Gene 2 COG0078 Ornithine carbamoyltransferase; ornithine carbamoyltransferase 2039007..2040023 Streptococcus pneumoniae AP200 9728210 YP_003877732.1 CDS SPAP_2199 NC_014494.1 2040188 2041135 D Operon 978 Gene 3 COG0549 Carbamate kinase; carbamate kinase 2040188..2041135 Streptococcus pneumoniae AP200 9728211 YP_003877733.1 CDS SPAP_2200 NC_014494.1 2041344 2042855 D Operon 979 Gene 1 COG1288 Predicted membrane protein; hypothetical protein 2041344..2042855 Streptococcus pneumoniae AP200 9728212 YP_003877734.1 CDS SPAP_2201 NC_014494.1 2042877 2044208 D Operon 979 Gene 2 COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; acetylornithine deacetylase/succinyl-diaminopimelate desuccinylase-like deacylases 2042877..2044208 Streptococcus pneumoniae AP200 9728213 YP_003877735.1 CDS SPAP_2202 NC_014494.1 2044613 2044777 R Operon 980 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2044613..2044777) Streptococcus pneumoniae AP200 9728214 YP_003877736.1 CDS SPAP_2203 NC_014494.1 2044749 2044904 R Operon 980 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(2044749..2044904) Streptococcus pneumoniae AP200 9728215 YP_003877737.1 CDS SPAP_2204 NC_014494.1 2044892 2045155 R Operon 980 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(2044892..2045155) Streptococcus pneumoniae AP200 9728216 YP_003877738.1 CDS SPAP_2205 NC_014494.1 2045542 2046441 R Operon 981 Gene 1 COG0330 Membrane protease subunits, stomatin/prohibitin homologs; membrane protease subunit complement(2045542..2046441) Streptococcus pneumoniae AP200 9728217 YP_003877739.1 CDS SPAP_2206 NC_014494.1 2046571 2047722 R Operon 982 Gene 1 COG1454 Alcohol dehydrogenase, class IV; alcohol dehydrogenase complement(2046571..2047722) Streptococcus pneumoniae AP200 9728218 YP_003877740.1 CDS SPAP_2207 NC_014494.1 2047868 2049634 R Operon 983 Gene 1 COG2407 L-fucose isomerase and related proteins; L-fucose isomerase-like protein complement(2047868..2049634) Streptococcus pneumoniae AP200 9728219 YP_003877741.1 CDS SPAP_2208 NC_014494.1 2049691 2052807 R Operon 983 Gene 2 Putative gene predicted by FgenesB; hypothetical protein complement(2049691..2052807) Streptococcus pneumoniae AP200 9728220 YP_003877742.1 CDS SPAP_2209 NC_014494.1 2052817 2055111 R Operon 983 Gene 3 Putative gene predicted by FgenesB; hypothetical protein complement(2052817..2055111) Streptococcus pneumoniae AP200 9728221 YP_003877743.1 CDS SPAP_2210 NC_014494.1 2055170 2055970 R Operon 984 Gene 1 COG3716 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IID complement(2055170..2055970) Streptococcus pneumoniae AP200 9728222 YP_003877744.1 CDS SPAP_2211 NC_014494.1 2055967 2056740 R Operon 984 Gene 2 COG3715 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIC complement(2055967..2056740) Streptococcus pneumoniae AP200 9728223 YP_003877745.1 CDS SPAP_2212 NC_014494.1 2056765 2057235 R Operon 984 Gene 3 COG3444 Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB; PTS system mannose/fructose/N-acetylgalactosamine-specific transporter subunit IIB complement(2056765..2057235) Streptococcus pneumoniae AP200 9728224 YP_003877746.1 CDS SPAP_2213 NC_014494.1 2057226 2057669 R Operon 984 Gene 4 COG2893 Phosphotransferase system, mannose/fructose-specific component IIA; PTS system mannose/fructose-specific transporter subunit IIA complement(2057226..2057669) Streptococcus pneumoniae AP200 9728225 YP_003877747.1 CDS SPAP_2214 NC_014494.1 2057650 2058090 R Operon 984 Gene 5 COG4154 Fucose dissimilation pathway protein FucU; fucose dissimilation pathway protein FucU complement(2057650..2058090) Streptococcus pneumoniae AP200 9728226 YP_003877748.1 CDS SPAP_2215 NC_014494.1 2058102 2058740 R Operon 984 Gene 6 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases; ribulose-5-phosphate 4-epimerase-like epimerase and aldolase complement(2058102..2058740) Streptococcus pneumoniae AP200 9728227 YP_003877749.1 CDS SPAP_2216 NC_014494.1 2058855 2060258 R Operon 985 Gene 1 COG1070 Sugar (pentulose and hexulose) kinases; sugar (pentulose and hexulose) kinase complement(2058855..2060258) Streptococcus pneumoniae AP200 9728228 YP_003877750.1 CDS SPAP_2217 NC_014494.1 2060434 2061207 D Operon 986 Gene 1 COG1349 Transcriptional regulators of sugar metabolism; sugar metabolism transcriptional regulator 2060434..2061207 Streptococcus pneumoniae AP200 9728229 YP_003877751.1 CDS SPAP_2218 NC_014494.1 2062027 2062125 D Operon 987 Gene 1 Putative gene predicted by FgenesB; hypothetical protein 2062027..2062125 Streptococcus pneumoniae AP200 9728230 YP_003877752.1 CDS SPAP_2219 NC_014494.1 2062378 2063883 R Operon 988 Gene 1 COG0803 ABC-type metal ion transport system, periplasmic component/surface adhesin; metal ion ABC transporter periplasmic protein/surface adhesin complement(2062378..2063883) Streptococcus pneumoniae AP200 9728231 YP_003877753.1 CDS SPAP_2220 NC_014494.1 2063893 2064699 R Operon 988 Gene 2 COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components; Mn2+/Zn2+ ABC transporter permease complement(2063893..2064699) Streptococcus pneumoniae AP200 9728232 YP_003877754.1 CDS SPAP_2221 NC_014494.1 2064692 2065396 R Operon 988 Gene 3 COG1121 ABC-type Mn/Zn transport systems, ATPase component; Mn/Zn ABC transporter ATPase complement(2064692..2065396) Streptococcus pneumoniae AP200 9728233 YP_003877755.1 CDS SPAP_2222 NC_014494.1 2065396 2065836 R Operon 988 Gene 4 COG1846 Transcriptional regulators; transcriptional regulator complement(2065396..2065836) Streptococcus pneumoniae AP200 9728234 YP_003877756.1 CDS SPAP_2223 NC_014494.1 2065991 2066497 R Operon 989 Gene 1 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) complement(2065991..2066497) Streptococcus pneumoniae AP200 9728235 YP_003877757.1 CDS SPAP_2224 NC_014494.1 2066472 2067260 R Operon 989 Gene 2 COG3966 Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein); protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) complement(2066472..2067260) Streptococcus pneumoniae AP200 9728236 YP_003877758.1 CDS SPAP_2225 NC_014494.1 2067253 2067492 R Operon 989 Gene 3 COG0236 Acyl carrier protein; acyl carrier protein complement(2067253..2067492) Streptococcus pneumoniae AP200 9728237 YP_003877759.1 CDS SPAP_2226 NC_014494.1 2067506 2068750 R Operon 989 Gene 4 COG1696 Predicted membrane protein involved in D-alanine export; hypothetical protein complement(2067506..2068750) Streptococcus pneumoniae AP200 9728238 YP_003877760.1 CDS SPAP_2227 NC_014494.1 2068747 2070297 R Operon 989 Gene 5 COG1020 Non-ribosomal peptide synthetase modules and related proteins; non-ribosomal peptide synthetase modules-like protein complement(2068747..2070297) Streptococcus pneumoniae AP200 9728239 YP_003877761.1 CDS SPAP_2228 NC_014494.1 2070680 2071384 R Operon 990 Gene 1 COG0580 Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family); glycerol uptake facilitator-like permease complement(2070680..2071384) Streptococcus pneumoniae AP200 9728240 YP_003877762.1 CDS SPAP_2229 NC_014494.1 2071454 2073280 R Operon 990 Gene 2 COG0578 Glycerol-3-phosphate dehydrogenase; glycerol-3-phosphate dehydrogenase complement(2071454..2073280) Streptococcus pneumoniae AP200 9728241 YP_003877763.1 CDS SPAP_2230 NC_014494.1 2073322 2074830 R Operon 990 Gene 3 COG0554 Glycerol kinase; glycerol kinase complement(2073322..2074830) Streptococcus pneumoniae AP200 9728242 YP_003877764.1 CDS SPAP_2231 NC_014494.1 2074989 2076416 R Operon 991 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2074989..2076416) Streptococcus pneumoniae AP200 9728243 YP_003877765.1 CDS SPAP_2232 NC_014494.1 2076581 2077453 D Operon 992 Gene 1 COG1281 Disulfide bond chaperones of the HSP33 family; HSP33 family disulfide bond chaperone 2076581..2077453 Streptococcus pneumoniae AP200 9728244 YP_003877766.1 CDS SPAP_2233 NC_014494.1 2077440 2078420 D Operon 992 Gene 2 COG0042 tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase 2077440..2078420 Streptococcus pneumoniae AP200 9728245 YP_003877767.1 CDS SPAP_2234 NC_014494.1 2078650 2080857 R Operon 993 Gene 1 COG5263 FOG: Choline binding protein A; choline binding protein A complement(2078650..2080857) Streptococcus pneumoniae AP200 9728246 YP_003877768.1 CDS SPAP_2235 NC_014494.1 2080936 2081463 R Operon 993 Gene 2 COG1755 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2080936..2081463) Streptococcus pneumoniae AP200 9728247 YP_003877769.1 CDS SPAP_2236 NC_014494.1 2081546 2082886 R Operon 994 Gene 1 COG0642 Signal transduction histidine kinase; signal transduction histidine kinase complement(2081546..2082886) Streptococcus pneumoniae AP200 9728248 YP_003877770.1 CDS SPAP_2237 NC_014494.1 2082883 2083536 R Operon 994 Gene 2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; CheY-like receiver/winged-helix DNA-binding domain-containing response regulator complement(2082883..2083536) Streptococcus pneumoniae AP200 9728249 YP_003877771.1 CDS SPAP_2238 NC_014494.1 2083845 2086277 R Operon 995 Gene 1 COG0542 ATPases with chaperone activity, ATP-binding subunit; ATPase complement(2083845..2086277) Streptococcus pneumoniae AP200 9728250 YP_003877772.1 CDS SPAP_2239 NC_014494.1 2086279 2086737 R Operon 995 Gene 2 COG4463 Transcriptional repressor of class III stress genes; transcriptional repressor of class III stress genes complement(2086279..2086737) Streptococcus pneumoniae AP200 9728251 YP_003877773.1 CDS SPAP_2240 NC_014494.1 2086856 2087584 R Operon 996 Gene 1 COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component; nitrate/sulfonate/bicarbonate ABC transporter ATPase complement(2086856..2087584) Streptococcus pneumoniae AP200 9728252 YP_003877774.1 CDS SPAP_2241 NC_014494.1 2087584 2088591 R Operon 996 Gene 2 COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components; nitrate/sulfonate/bicarbonate ABC transporter periplasmic protein complement(2087584..2088591) Streptococcus pneumoniae AP200 9728253 YP_003877775.1 CDS SPAP_2242 NC_014494.1 2088630 2089388 R Operon 996 Gene 3 COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component; nitrate/sulfonate/bicarbonate ABC transporter permease complement(2088630..2089388) Streptococcus pneumoniae AP200 9728254 YP_003877776.1 CDS SPAP_2243 NC_014494.1 2089351 2089641 R Operon 996 Gene 4 COG0011 Uncharacterized conserved protein; hypothetical protein complement(2089351..2089641) Streptococcus pneumoniae AP200 9728255 YP_003877777.1 CDS SPAP_2244 NC_014494.1 2089897 2091153 R Operon 997 Gene 1 COG3942 Choline binding protein D; choline binding protein D complement(2089897..2091153) Streptococcus pneumoniae AP200 9728256 YP_003877778.1 CDS SPAP_2245 NC_014494.1 2091332 2091598 R Operon 998 Gene 1 COG4466 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2091332..2091598) Streptococcus pneumoniae AP200 9728257 YP_003877779.1 CDS SPAP_2246 NC_014494.1 2091600 2092952 R Operon 998 Gene 2 COG0305 Replicative DNA helicase; Replicative DNA helicase complement(2091600..2092952) Streptococcus pneumoniae AP200 9728258 YP_003877780.1 CDS SPAP_2247 NC_014494.1 2092996 2093448 R Operon 998 Gene 3 protein supported gi|15902011|ref|NP_346615.1| 50S ribosomal protein L9; hypothetical protein complement(2092996..2093448) Streptococcus pneumoniae AP200 9728259 YP_003877781.1 CDS SPAP_2248 NC_014494.1 2093445 2095319 R Operon 998 Gene 4 COG3887 Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain; putative signaling protein complement(2093445..2095319) Streptococcus pneumoniae AP200 9728260 YP_003877782.1 CDS SPAP_2249 NC_014494.1 2095554 2096102 R Operon 999 Gene 1 protein supported gi|148984509|ref|ZP_01817797.1| ribosomal subunit interface protein; hypothetical protein complement(2095554..2096102) Streptococcus pneumoniae AP200 9728261 YP_003877783.1 CDS SPAP_2250 NC_014494.1 2096182 2096520 R Operon 999 Gene 2 COG1040 Predicted amidophosphoribosyltransferases; putative amidophosphoribosyltransferase complement(2096182..2096520) Streptococcus pneumoniae AP200 9728262 YP_003877784.1 CDS SPAP_2251 NC_014494.1 2096841 2098139 R Operon 1000 Gene 1 COG4098 Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein); superfamily II DNA/RNA helicase complement(2096841..2098139) Streptococcus pneumoniae AP200 9728263 YP_003877785.1 CDS SPAP_2252 NC_014494.1 2098195 2098830 D Operon 1001 Gene 1 COG1739 Uncharacterized conserved protein; hypothetical protein 2098195..2098830 Streptococcus pneumoniae AP200 9728264 YP_003877786.1 CDS SPAP_2253 NC_014494.1 2099115 2100035 D Operon 1002 Gene 1 protein supported gi|148988856|ref|ZP_01820271.1| 50S ribosomal protein L9; hypothetical protein 2099115..2100035 Streptococcus pneumoniae AP200 9728265 YP_003877787.1 CDS SPAP_2254 NC_014494.1 2100232 2100501 R Operon 1003 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_6 complement(2100232..2100501) Streptococcus pneumoniae AP200 9728266 YP_003877788.1 CDS SPAP_2255 NC_014494.1 2100667 2100933 D Operon 1004 Gene 1 COG3335 Transposase and inactivated derivatives; transposase-like protein, ISSpn2 2100667..2100933 Streptococcus pneumoniae AP200 9728267 YP_003877789.1 CDS SPAP_2256 NC_014494.1 2101124 2101411 R Operon 1005 Gene 1 COG3436 Transposase and inactivated derivatives; transposase-like protein, ISSpn_AP200_7 complement(2101124..2101411) Streptococcus pneumoniae AP200 9728268 YP_003877790.1 CDS SPAP_2257 NC_014494.1 2101657 2102697 R Operon 1006 Gene 1 COG0264 Translation elongation factor Ts; translation elongation factor Ts complement(2101657..2102697) Streptococcus pneumoniae AP200 9728269 YP_003877791.2 CDS SPAP_2258 NC_014494.1 2102776 2103555 R Operon 1006 Gene 2 protein supported gi|242244394|ref|ZP_04798831.1| 30S ribosomal protein S2; 30S ribosomal protein S2 complement(2102776..2103555) Streptococcus pneumoniae AP200 9728270 YP_003877792.1 CDS SPAP_2259 NC_014494.1 2103779 2104957 R Operon 1007 Gene 1 COG3883 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2103779..2104957) Streptococcus pneumoniae AP200 9728271 YP_003877793.1 CDS SPAP_2260 NC_014494.1 2105050 2105544 R Operon 1007 Gene 2 COG2891 Cell shape-determining protein; cell shape-determining protein complement(2105050..2105544) Streptococcus pneumoniae AP200 9728272 YP_003877794.1 CDS SPAP_2261 NC_014494.1 2105544 2106362 R Operon 1007 Gene 3 COG1792 Cell shape-determining protein; cell shape-determining protein complement(2105544..2106362) Streptococcus pneumoniae AP200 9728273 YP_003877795.1 CDS SPAP_2262 NC_014494.1 2106421 2107215 R Operon 1007 Gene 4 COG0619 ABC-type cobalt transport system, permease component CbiQ and related transporters; cobalt ABC transporter permease CbiQ-like transporter complement(2106421..2107215) Streptococcus pneumoniae AP200 9728274 YP_003877796.1 CDS SPAP_2263 NC_014494.1 2107208 2108047 R Operon 1007 Gene 5 COG1122 ABC-type cobalt transport system, ATPase component; cobalt ABC transporter ATPase complement(2107208..2108047) Streptococcus pneumoniae AP200 9728275 YP_003877797.1 CDS SPAP_2264 NC_014494.1 2108032 2108859 R Operon 1007 Gene 6 protein supported gi|229849245|ref|ZP_04469311.1| LSU ribosomal protein L17P; hypothetical protein complement(2108032..2108859) Streptococcus pneumoniae AP200 9728276 YP_003877798.1 CDS SPAP_2265 NC_014494.1 2108856 2109401 R Operon 1007 Gene 7 COG0558 Phosphatidylglycerophosphate synthase; phosphatidylglycerophosphate synthase complement(2108856..2109401) Streptococcus pneumoniae AP200 9728277 YP_003877799.1 CDS SPAP_2266 NC_014494.1 2109412 2110233 R Operon 1007 Gene 8 COG1426 Uncharacterized protein conserved in bacteria; hypothetical protein complement(2109412..2110233) Streptococcus pneumoniae AP200 9728278 YP_003877800.1 CDS SPAP_2267 NC_014494.1 2110275 2111558 R Operon 1007 Gene 9 COG0612 Predicted Zn-dependent peptidases; putative Zn-dependent peptidase complement(2110275..2111558) Streptococcus pneumoniae AP200 9728279 YP_003877801.1 CDS SPAP_2268 NC_014494.1 2111555 2112805 R Operon 1007 Gene 10 COG0612 Predicted Zn-dependent peptidases; putative Zn-dependent peptidase complement(2111555..2112805) Streptococcus pneumoniae AP200 9728280 YP_003877802.1 CDS SPAP_2269 NC_014494.1 2112964 2113332 D Operon 1008 Gene 1 protein supported gi|15904072|ref|NP_359622.1| hypothetical protein spr2031; hypothetical protein 2112964..2113332 Streptococcus pneumoniae AP200 9728281 YP_003877803.1 CDS SPAP_2270 NC_014494.1 2113335 2114432 D Operon 1008 Gene 2 COG1195 Recombinational DNA repair ATPase (RecF pathway); recombinational DNA repair ATPase 2113335..2114432 Streptococcus pneumoniae AP200 9728282 YP_003877804.1 CDS SPAP_2271 NC_014494.1 2114483 2115961 R Operon 1009 Gene 1 COG0516 IMP dehydrogenase/GMP reductase; IMP dehydrogenase/GMP reductase complement(2114483..2115961) Streptococcus pneumoniae AP200 9728283 YP_003877805.1 CDS SPAP_2272 NC_014494.1 2116113 2117138 R Operon 1010 Gene 1 COG0180 Tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase complement(2116113..2117138) Streptococcus pneumoniae AP200 9728284 YP_003877806.1 CDS SPAP_2273 NC_014494.1 2117344 2118966 D Operon 1011 Gene 1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains; ABC transporter ATPase 2117344..2118966 Streptococcus pneumoniae AP200 9728285 YP_003877807.1 CDS SPAP_2274 NC_014494.1 2119028 2121580 D Operon 1011 Gene 2 COG4485 Predicted membrane protein; hypothetical protein 2119028..2121580 Streptococcus pneumoniae AP200 9728286 YP_003877808.1 CDS SPAP_2275 NC_014494.1 2121681 2121995 R Operon 1012 Gene 1 COG1511 Predicted membrane protein; hypothetical protein complement(2121681..2121995) Streptococcus pneumoniae AP200 9728287 YP_003877809.1 CDS SPAP_2276 NC_014494.1 2122023 2123138 R Operon 1012 Gene 2 COG1511 Predicted membrane protein; hypothetical protein complement(2122023..2123138) Streptococcus pneumoniae AP200 9728288 YP_003877810.1 CDS SPAP_2277 NC_014494.1 2123369 2123836 D Operon 1013 Gene 1 COG1309 Transcriptional regulator; transcriptional regulator 2123369..2123836 Streptococcus pneumoniae AP200 9728289 YP_003877811.1 CDS SPAP_2280 NC_014494.1 2124154 2124906 R Operon 1014 Gene 1 COG3279 Response regulator of the LytR/AlgR family; LytR/AlgR family response regulator complement(2124154..2124906) Streptococcus pneumoniae AP200 9728292 YP_003877812.1 CDS SPAP_2281 NC_014494.1 2124903 2126228 R Operon 1014 Gene 2 COG2972 Predicted signal transduction protein with a C-terminal ATPase domain; putative signal transduction protein complement(2124903..2126228) Streptococcus pneumoniae AP200 9728293 YP_003877813.1 CDS SPAP_2283 NC_014494.1 2126413 2126931 R transposase-like protein, IS1239 complement(2126413..2126931) Streptococcus pneumoniae AP200 9728294 YP_003877814.1 CDS SPAP_2284 NC_014494.1 2126951 2127253 R transposase-like protein, IS1239 complement(2126951..2127253) Streptococcus pneumoniae AP200 9728295 YP_003877815.1 CDS SPAP_2285 NC_014494.1 2127476 2127622 R Operon 1016 Gene 1 Putative gene predicted by FgenesB; hypothetical protein complement(2127476..2127622) Streptococcus pneumoniae AP200 9728296 YP_003877816.1 CDS SPAP_2287 NC_014494.1 2127905 2128384 R Operon 1016 Gene 2 COG1576 Uncharacterized conserved protein; hypothetical protein complement(2127905..2128384) Streptococcus pneumoniae AP200 9728298 YP_003877817.1 CDS SPAP_2288 NC_014494.1 2128555 2129748 D Operon 1017 Gene 1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; trypsin-like serine protease 2128555..2129748 Streptococcus pneumoniae AP200 9728299 YP_003877818.1 CDS SPAP_2289 NC_014494.1 2129806 2130564 D Operon 1017 Gene 2 COG1475 Predicted transcriptional regulators; putative transcriptional regulator 2129806..2130564 Streptococcus pneumoniae AP200 9728300 SPAP_0015 tRNA SPAP_0015 NC_014494.1 15025 15096 D tRNA-Glu 15025..15096 Streptococcus pneumoniae AP200 9726032 SPAP_0017 tRNA SPAP_0017 NC_014494.1 16947 17019 D tRNA-Ala 16947..17019 Streptococcus pneumoniae AP200 9726034 SPAP_0020 tRNA SPAP_0020 NC_014494.1 20243 20316 D tRNA-Asn 20243..20316 Streptococcus pneumoniae AP200 9726037 SPAP_0830 tRNA SPAP_0830 NC_014494.1 787323 787403 D tRNA-Tyr 787323..787403 Streptococcus pneumoniae AP200 9726846 SPAP_0831 tRNA SPAP_0831 NC_014494.1 787413 787484 D tRNA-Gln 787413..787484 Streptococcus pneumoniae AP200 9726847 SPAP_0847 tRNA SPAP_0847 NC_014494.1 802005 802092 R tRNA-Ser complement(802005..802092) Streptococcus pneumoniae AP200 9726862 SPAP_1185 tRNA SPAP_1185 NC_014494.1 1122945 1123017 R tRNA-Thr complement(1122945..1123017) Streptococcus pneumoniae AP200 9727200 SPAP_1273 tRNA SPAP_1273 NC_014494.1 1212219 1212290 R tRNA-Arg complement(1212219..1212290) Streptococcus pneumoniae AP200 9727288 SPAP_1319 tRNA SPAP_1319 NC_014494.1 1256237 1256308 R tRNA-Arg complement(1256237..1256308) Streptococcus pneumoniae AP200 9727334 SPAP_1603 tRNA SPAP_1603 NC_014494.1 1509101 1509186 R tRNA-Leu complement(1509101..1509186) Streptococcus pneumoniae AP200 9727617 SPAP_1782 tRNA SPAP_1782 NC_014494.1 1679952 1680024 D tRNA-Lys 1679952..1680024 Streptococcus pneumoniae AP200 9727796 SPAP_1899 tRNA SPAP_1899 NC_014494.1 1791126 1791213 R tRNA-Ser complement(1791126..1791213) Streptococcus pneumoniae AP200 9727913 SPAP_1900 tRNA SPAP_1900 NC_014494.1 1791220 1791293 R tRNA-Ile complement(1791220..1791293) Streptococcus pneumoniae AP200 9727914 SPAP_1901 tRNA SPAP_1901 NC_014494.1 1791329 1791399 R tRNA-Gly complement(1791329..1791399) Streptococcus pneumoniae AP200 9727915 SPAP_1902 tRNA SPAP_1902 NC_014494.1 1791419 1791491 R tRNA-Phe complement(1791419..1791491) Streptococcus pneumoniae AP200 9727916 SPAP_1903 tRNA SPAP_1903 NC_014494.1 1791495 1791568 R tRNA-Met complement(1791495..1791568) Streptococcus pneumoniae AP200 9727917 SPAP_1904 tRNA SPAP_1904 NC_014494.1 1791689 1791762 R tRNA-Met complement(1791689..1791762) Streptococcus pneumoniae AP200 9727918 SPAP_1905 tRNA SPAP_1905 NC_014494.1 1791776 1791849 R tRNA-OTHER complement(1791776..1791849) Streptococcus pneumoniae AP200 9727919 SPAP_1906 tRNA SPAP_1906 NC_014494.1 1791855 1791927 R tRNA-OTHER complement(1791855..1791927) Streptococcus pneumoniae AP200 9727920 SPAP_1907 tRNA SPAP_1907 NC_014494.1 1792026 1792111 R tRNA-Leu complement(1792026..1792111) Streptococcus pneumoniae AP200 9727921 SPAP_1908 tRNA SPAP_1908 NC_014494.1 1792119 1792192 R tRNA-Gly complement(1792119..1792192) Streptococcus pneumoniae AP200 9727922 SPAP_1909 tRNA SPAP_1909 NC_014494.1 1792215 1792287 R tRNA-Thr complement(1792215..1792287) Streptococcus pneumoniae AP200 9727923 SPAP_1910 tRNA SPAP_1910 NC_014494.1 1792306 1792387 R tRNA-Leu complement(1792306..1792387) Streptococcus pneumoniae AP200 9727924 SPAP_1911 tRNA SPAP_1911 NC_014494.1 1792393 1792465 R tRNA-Lys complement(1792393..1792465) Streptococcus pneumoniae AP200 9727925 SPAP_1912 tRNA SPAP_1912 NC_014494.1 1792490 1792562 R tRNA-Asp complement(1792490..1792562) Streptococcus pneumoniae AP200 9727926 SPAP_1913 tRNA SPAP_1913 NC_014494.1 1792565 1792637 R tRNA-Val complement(1792565..1792637) Streptococcus pneumoniae AP200 9727927 SPAP_1916 tRNA SPAP_1916 NC_014494.1 1795862 1795934 R tRNA-Ala complement(1795862..1795934) Streptococcus pneumoniae AP200 9727930 SPAP_1918 tRNA SPAP_1918 NC_014494.1 1797784 1797855 R tRNA-Glu complement(1797784..1797855) Streptococcus pneumoniae AP200 9727932 SPAP_1972 tRNA SPAP_1972 NC_014494.1 1845445 1845515 D tRNA-Cys 1845445..1845515 Streptococcus pneumoniae AP200 9727986 SPAP_2018 tRNA SPAP_2018 NC_014494.1 1883867 1883940 R tRNA-Pro complement(1883867..1883940) Streptococcus pneumoniae AP200 9728032 SPAP_2019 tRNA SPAP_2019 NC_014494.1 1883956 1884029 R tRNA-Arg complement(1883956..1884029) Streptococcus pneumoniae AP200 9728033 SPAP_2020 tRNA SPAP_2020 NC_014494.1 1884039 1884124 R tRNA-Leu complement(1884039..1884124) Streptococcus pneumoniae AP200 9728034 SPAP_2021 tRNA SPAP_2021 NC_014494.1 1884132 1884203 R tRNA-Gly complement(1884132..1884203) Streptococcus pneumoniae AP200 9728035 SPAP_2290 tRNA SPAP_2290 NC_014494.1 1884225 1884299 R tRNA-Thr complement(1884225..1884299) Streptococcus pneumoniae AP200 9728036 SPAP_2022 tRNA SPAP_2022 NC_014494.1 1884318 1884399 R tRNA-Leu complement(1884318..1884399) Streptococcus pneumoniae AP200 9728301 SPAP_2023 tRNA SPAP_2023 NC_014494.1 1884405 1884477 R tRNA-Lys complement(1884405..1884477) Streptococcus pneumoniae AP200 9728037 SPAP_2024 tRNA SPAP_2024 NC_014494.1 1884502 1884574 R tRNA-Asp complement(1884502..1884574) Streptococcus pneumoniae AP200 9728038 SPAP_2025 tRNA SPAP_2025 NC_014494.1 1884577 1884649 R tRNA-Val complement(1884577..1884649) Streptococcus pneumoniae AP200 9728039 SPAP_2028 tRNA SPAP_2028 NC_014494.1 1887874 1887946 R tRNA-Ala complement(1887874..1887946) Streptococcus pneumoniae AP200 9728042 SPAP_2030 tRNA SPAP_2030 NC_014494.1 1889796 1889867 R tRNA-Glu complement(1889796..1889867) Streptococcus pneumoniae AP200 9728044 SPAP_2097 tRNA SPAP_2097 NC_014494.1 1947669 1947752 R tRNA-Leu complement(1947669..1947752) Streptococcus pneumoniae AP200 9728111 SPAP_2098 tRNA SPAP_2098 NC_014494.1 1947762 1947833 R tRNA-Gln complement(1947762..1947833) Streptococcus pneumoniae AP200 9728112 SPAP_2099 tRNA SPAP_2099 NC_014494.1 1947844 1947916 R tRNA-His complement(1947844..1947916) Streptococcus pneumoniae AP200 9728113 SPAP_2101 tRNA SPAP_2101 NC_014494.1 1947931 1948001 R tRNA-Trp complement(1947931..1948001) Streptococcus pneumoniae AP200 9728114 SPAP_2102 tRNA SPAP_2102 NC_014494.1 1948006 1948086 R tRNA-Tyr complement(1948006..1948086) Streptococcus pneumoniae AP200 9728115 SPAP_2103 tRNA SPAP_2103 NC_014494.1 1948099 1948171 R tRNA-Phe complement(1948099..1948171) Streptococcus pneumoniae AP200 9728116 SPAP_2104 tRNA SPAP_2104 NC_014494.1 1948175 1948248 R tRNA-Met complement(1948175..1948248) Streptococcus pneumoniae AP200 9728117 SPAP_2105 tRNA SPAP_2105 NC_014494.1 1948262 1948351 R tRNA-Ser complement(1948262..1948351) Streptococcus pneumoniae AP200 9728118 SPAP_2107 tRNA SPAP_2107 NC_014494.1 1948434 1948507 R tRNA-Ile complement(1948434..1948507) Streptococcus pneumoniae AP200 9728119 SPAP_2108 tRNA SPAP_2108 NC_014494.1 1948542 1948612 R tRNA-Gly complement(1948542..1948612) Streptococcus pneumoniae AP200 9728120 SPAP_2109 tRNA SPAP_2109 NC_014494.1 1948618 1948690 R tRNA-Val complement(1948618..1948690) Streptococcus pneumoniae AP200 9728121 SPAP_2112 tRNA SPAP_2112 NC_014494.1 1951914 1951986 R tRNA-Ala complement(1951914..1951986) Streptococcus pneumoniae AP200 9728124 SPAP_2114 tRNA SPAP_2114 NC_014494.1 1953838 1953909 R tRNA-Glu complement(1953838..1953909) Streptococcus pneumoniae AP200 9728126 SPAP_2278 tRNA SPAP_2278 NC_014494.1 2123952 2124025 R tRNA-Asn complement(2123952..2124025) Streptococcus pneumoniae AP200 9728290 SPAP_2279 tRNA SPAP_2279 NC_014494.1 2124031 2124102 R tRNA-Glu complement(2124031..2124102) Streptococcus pneumoniae AP200 9728291 SPAP_2286 tRNA SPAP_2286 NC_014494.1 2127788 2127861 R tRNA-Arg complement(2127788..2127861) Streptococcus pneumoniae AP200 9728297 SPAP_0016 rRNA SPAP_0016 NC_014494.1 15364 16894 D 16S ribosomal RNA 15364..16894 Streptococcus pneumoniae AP200 9726033 SPAP_0018 rRNA SPAP_0018 NC_014494.1 17144 20045 D 23S ribosomal RNA 17144..20045 Streptococcus pneumoniae AP200 9726035 SPAP_0019 rRNA SPAP_0019 NC_014494.1 20115 20262 D 5S ribosomal RNA 20115..20262 Streptococcus pneumoniae AP200 9726036 SPAP_1914 rRNA SPAP_1914 NC_014494.1 1792638 1792765 R 5S ribosomal RNA complement(1792638..1792765) Streptococcus pneumoniae AP200 9727928 SPAP_1915 rRNA SPAP_1915 NC_014494.1 1792836 1795737 R 23S ribosomal RNA complement(1792836..1795737) Streptococcus pneumoniae AP200 9727929 SPAP_1917 rRNA SPAP_1917 NC_014494.1 1795987 1797524 R 16S ribosomal RNA complement(1795987..1797524) Streptococcus pneumoniae AP200 9727931 SPAP_2026 rRNA SPAP_2026 NC_014494.1 1884650 1884776 R 5S ribosomal RNA complement(1884650..1884776) Streptococcus pneumoniae AP200 9728040 SPAP_2027 rRNA SPAP_2027 NC_014494.1 1884848 1887749 R 23S ribosomal RNA complement(1884848..1887749) Streptococcus pneumoniae AP200 9728041 SPAP_2029 rRNA SPAP_2029 NC_014494.1 1887999 1889536 R 16S ribosomal RNA complement(1887999..1889536) Streptococcus pneumoniae AP200 9728043 SPAP_2110 rRNA SPAP_2110 NC_014494.1 1948691 1948817 R 5S ribosomal RNA complement(1948691..1948817) Streptococcus pneumoniae AP200 9728122 SPAP_2111 rRNA SPAP_2111 NC_014494.1 1948887 1951789 R 23S ribosomal RNA complement(1948887..1951789) Streptococcus pneumoniae AP200 9728123 SPAP_2113 rRNA SPAP_2113 NC_014494.1 1952039 1953578 R 16S ribosomal RNA complement(1952039..1953578) Streptococcus pneumoniae AP200 9728125