-- dump date 20140620_072443 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 573413000001 SEQ_END SEQ_END NC_014364.1 4653970 4653970 DR NC_014364.1; contig end 4653970..4653970 Spirochaeta smaragdinae DSM 11293 YP_003801755.1 CDS Spirs_0001 NC_014364.1 150 1565 D COGs: COG0593 ATPase involved in DNA replication initiation; InterProIPR020591:IPR001957:IPR003593:IPR013159:IPR 013317; KEGG: tde:TDE0001 chromosomal replication initiation protein; PFAM: Chromosomal replication initiator DnaA; Chromosomal replication initiator DnaA domain; SMART: replication initiation factor DnaA; ATPase AAA; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: chromosomal replication initiator protein DnaA; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA; chromosomal replication initiator protein DnaA 150..1565 Spirochaeta smaragdinae DSM 11293 9492211 YP_003801756.1 CDS Spirs_0002 NC_014364.1 1565 1741 D hypothetical protein 1565..1741 Spirochaeta smaragdinae DSM 11293 9488073 YP_003801757.1 CDS Spirs_0003 NC_014364.1 1768 2871 D COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR001001; KEGG: tde:TDE0231 DNA polymerase III beta subunit; PFAM: DNA polymerase III beta chain; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III beta chain; SPTR: DNA polymerase III subunit beta; TIGRFAM: DNA polymerase III subunit beta; PFAM: DNA polymerase III subunit beta, C-terminal domain; DNA polymerase III subunit beta, N-terminal domain; DNA polymerase III subunit beta, central domain; TIGRFAM: DNA polymerase III subunit beta; DNA polymerase III subunit beta 1768..2871 Spirochaeta smaragdinae DSM 11293 9488074 YP_003801758.1 CDS Spirs_0004 NC_014364.1 2880 3956 D COGs: COG1195 recombinational DNA repair ATPase (RecF pathway); InterPro IPR001238:IPR003395:IPR018078; KEGG: tde:TDE0230 DNA replication and repair protein RecF; PFAM: SMC domain protein; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein; DNA replication and repair protein RecF 2880..3956 Spirochaeta smaragdinae DSM 11293 9488075 YP_003801759.1 CDS Spirs_0005 NC_014364.1 3965 4435 D InterPro IPR007922; KEGG: vpr:Vpar_0005 protein of unknown function DUF721; PFAM: protein of unknown function DUF721; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF721); hypothetical protein 3965..4435 Spirochaeta smaragdinae DSM 11293 9488076 YP_003801760.1 CDS Spirs_0006 NC_014364.1 4517 4672 D InterPro IPR000271; KEGG: btu:BT0440 50S ribosomal protein L34; PFAM: ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: ribosomal protein L34; PFAM: ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type; 50S ribosomal protein L34 4517..4672 Spirochaeta smaragdinae DSM 11293 9488077 YP_003801761.1 CDS Spirs_0007 NC_014364.1 4683 5030 D InterPro IPR000100:IPR020539; KEGG: tde:TDE2399 ribonuclease P protein component; PFAM: ribonuclease P protein; SPTR: ribonuclease P protein component; TIGRFAM: ribonuclease P protein component; manually curated; PFAM: ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial; ribonuclease P protein component 4683..5030 Spirochaeta smaragdinae DSM 11293 9488078 YP_003801762.1 CDS Spirs_0008 NC_014364.1 5039 6796 D COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708:IPR013308:IPR019998:IPR020001; KEGG: tde:TDE2396 inner membrane protein translocase component YidC; PFAM: 60 kDa inner membrane insertion protein; SPTR: Inner membrane protein OxaA; TIGRFAM: membrane protein insertase, YidC/Oxa1 family; membrane protein insertase, YidC/Oxa1 family domain containing; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain; membrane protein insertase, YidC/Oxa1 family, N-terminal domain; YidC/Oxa1 family membrane protein insertase 5039..6796 Spirochaeta smaragdinae DSM 11293 9488079 YP_003801763.1 CDS Spirs_0009 NC_014364.1 6836 7519 D COGs: COG1847 RNA-binding protein; InterPro IPR001374:IPR004088; KEGG: tde:TDE2395 Jag protein, PFAM: single-stranded nucleic acid binding R3H domain protein; SMART: single-stranded nucleic acid binding R3H domain protein; SPTR: protein jag; PFAM: R3H domain; single-stranded nucleic acid binding R3H domain-containing protein 6836..7519 Spirochaeta smaragdinae DSM 11293 9488080 YP_003801764.1 CDS Spirs_0010 NC_014364.1 7607 8773 D COGs: COG0192 S-adenosylmethionine synthetase; InterPro IPR002133; KEGG: tde:TDE2470 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase; PRIAM: methionine adenosyltransferase; SPTR: S-adenosylmethionine synthetase; TIGRFAM: S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase; S-adenosylmethionine synthetase 7607..8773 Spirochaeta smaragdinae DSM 11293 9488081 YP_003801765.1 CDS Spirs_0011 NC_014364.1 8785 9717 D COGs: COG2431 membrane protein; InterPro IPR005642; KEGG: vvy:VV1444 hypothetical protein; PFAM: protein of unknown function DUF340 membrane; SPTR: uncharacterized protein; PFAM: membrane protein of unknown function (DUF340); hypothetical protein 8785..9717 Spirochaeta smaragdinae DSM 11293 9488082 YP_003801766.1 CDS Spirs_0012 NC_014364.1 9730 10791 R InterPro IPR004843; KEGG: cch:Cag_0430 hypothetical protein; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; metallophosphoesterase complement(9730..10791) Spirochaeta smaragdinae DSM 11293 9488083 YP_003801767.1 CDS Spirs_0013 NC_014364.1 10866 11339 R COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: cca:CCA00348 PTS system,IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS system,IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS IIA-like nitrogen-regulatory protein PtsN complement(10866..11339) Spirochaeta smaragdinae DSM 11293 9488084 YP_003801768.1 CDS Spirs_0014 NC_014364.1 11411 11728 D COGs: COG0633 Ferredoxin; InterPro IPR001041; KEGG: lic:LIC12506 adenylate/guanylate cyclase; PFAM: ferredoxin; SPTR: adenylate cyclase; PFAM: 2Fe-2S iron-sulfur cluster binding domain; ferredoxin 11411..11728 Spirochaeta smaragdinae DSM 11293 9488085 YP_003801769.1 CDS Spirs_0015 NC_014364.1 11795 12805 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: sth:STH770 LacI family transcriptional repressor; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional repressor; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 11795..12805 Spirochaeta smaragdinae DSM 11293 9488086 YP_003801770.1 CDS Spirs_0016 NC_014364.1 13031 14173 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: lsp:Bsph_4187 NAD-dependent methanol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 13031..14173 Spirochaeta smaragdinae DSM 11293 9488087 YP_003801771.1 CDS Spirs_0017 NC_014364.1 14170 14577 R COGs: COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; InterPro IPR002579; KEGG: bpt:Bpet1710 methionine sulfoxide reductase B; PFAM: methionine sulfoxide reductase B; PRIAM: peptide-methionine (R)-S-oxide reductase; SPTR: peptide methionine sulfoxide reductase; TIGRFAM: methionine-R-sulfoxide reductase; PFAM: SelR domain; TIGRFAM: methionine-R-sulfoxide reductase; methionine-R-sulfoxide reductase complement(14170..14577) Spirochaeta smaragdinae DSM 11293 9488088 YP_003801772.1 CDS Spirs_0018 NC_014364.1 14633 15154 D COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: bvu:BVU_2535 NADH dehydrogenase/NAD(P)H nitroreductase; PFAM: nitroreductase; SPTR: NADPH-oxidoreductase; PFAM: nitroreductase family; nitroreductase 14633..15154 Spirochaeta smaragdinae DSM 11293 9488089 YP_003801773.1 CDS Spirs_0019 NC_014364.1 15219 16184 R KEGG: gem:GM21_3782 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(15219..16184) Spirochaeta smaragdinae DSM 11293 9488090 YP_003801774.1 CDS Spirs_0020 NC_014364.1 16325 17554 D COGs: COG0426 flavoprotein; InterPro IPR008254:IPR016440; KEGG: pca:Pcar_2284 uncharacterized flavoprotein; SPTR: Uncharacterized flavoprotein; PFAM: metallo-beta-lactamase superfamily; flavoprotein 16325..17554 Spirochaeta smaragdinae DSM 11293 9488091 YP_003801775.1 CDS Spirs_0021 NC_014364.1 17596 18168 D KEGG: mta:Moth_2057 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1393); hypothetical protein 17596..18168 Spirochaeta smaragdinae DSM 11293 9488092 YP_003801776.1 CDS Spirs_0022 NC_014364.1 18168 19775 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR001638:IPR003594:IPR011495:IPR005467; KEGG: rci:LRC120 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; extracellular solute-binding protein family 3; SPTR: Multi-sensor signal transduction multi-kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular solute-binding proteins, family 3; signal transduction histidine kinase 18168..19775 Spirochaeta smaragdinae DSM 11293 9488093 YP_003801777.1 CDS Spirs_0023 NC_014364.1 19760 20260 R KEGG: ppu:PP_0636 cold shock DNA-binding domain-containing protein; SPTR: uncharacterized protein; hypothetical protein complement(19760..20260) Spirochaeta smaragdinae DSM 11293 9488094 YP_003801778.1 CDS Spirs_0024 NC_014364.1 20456 21319 D COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: cdl:CDR20291_1955 RpiR-family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator 20456..21319 Spirochaeta smaragdinae DSM 11293 9488095 YP_003801779.1 CDS Spirs_0025 NC_014364.1 21403 22392 D COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: fnu:FN0397 peptide ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; peptide ABC transporter permease 21403..22392 Spirochaeta smaragdinae DSM 11293 9488096 YP_003801780.1 CDS Spirs_0026 NC_014364.1 22389 23273 D COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: fnu:FN0398 peptide ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; peptide ABC transporter permease 22389..23273 Spirochaeta smaragdinae DSM 11293 9488097 YP_003801781.1 CDS Spirs_0027 NC_014364.1 23285 24262 D COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR010066:IPR003593:IPR003439:IPR013563:IPR 017871; KEGG: fnu:FN0399 peptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 23285..24262 Spirochaeta smaragdinae DSM 11293 9488098 YP_003801782.1 CDS Spirs_0028 NC_014364.1 24264 25232 D COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterPro IPR010066:IPR003593:IPR003439:IPR013563; KEGG: aco:Amico_0787 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: oligopeptide transport ATP-binding protein AppF; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 24264..25232 Spirochaeta smaragdinae DSM 11293 9488099 YP_003801783.1 CDS Spirs_0029 NC_014364.1 25281 26810 D COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: fnu:FN0396 dipeptide-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein 25281..26810 Spirochaeta smaragdinae DSM 11293 9488100 YP_003801784.1 CDS Spirs_0030 NC_014364.1 26872 27633 D COGs: COG1402 Uncharacterized protein amidase; InterPro IPR003785:IPR019775; KEGG: aco:Amico_0022 creatininase; PFAM: creatininase; SPTR: uncharacterized protein; PFAM: Creatinine amidohydrolase; creatininase 26872..27633 Spirochaeta smaragdinae DSM 11293 9488101 YP_003801785.1 CDS Spirs_0031 NC_014364.1 27640 28716 D COGs: COG1363 cellulase M and related protein; InterPro IPR008007; KEGG: efa:EF2724 M42 family peptidase; PFAM: peptidase M42 family protein; PRIAM: glutamyl aminopeptidase; SPTR: uncharacterized protein; PFAM: M42 glutamyl aminopeptidase; glutamyl aminopeptidase 27640..28716 Spirochaeta smaragdinae DSM 11293 9488102 YP_003801786.1 CDS Spirs_0032 NC_014364.1 28718 29767 D KEGG: cvi:CV_4032 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 28718..29767 Spirochaeta smaragdinae DSM 11293 9488103 YP_003801787.1 CDS Spirs_0033 NC_014364.1 29771 31648 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004090:IPR003660:IPR004089; KEGG: dde:Dde_0347 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; protein of unknown function (DUF3365); methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(29771..31648) Spirochaeta smaragdinae DSM 11293 9488104 YP_003801788.1 CDS Spirs_0034 NC_014364.1 31684 33150 R COGs: COG2195 Di- and tripeptidase; InterPro IPR001160:IPR002933:IPR011650; KEGG: bfs:BF3079 aminoacyl-histidine dipeptidase; PFAM: peptidase dimerisation domain protein; peptidase M20; PRIAM: Xaa-His dipeptidase; SPTR: Aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: aminoacyl-histidine dipeptidase; aminoacyl-histidine dipeptidase complement(31684..33150) Spirochaeta smaragdinae DSM 11293 9488105 YP_003801789.1 CDS Spirs_0035 NC_014364.1 33396 34613 D InterPro IPR001647; KEGG: reh:H16_B0715 TetR/AcrR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR/AcrR-family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 33396..34613 Spirochaeta smaragdinae DSM 11293 9488106 YP_003801790.1 CDS Spirs_0036 NC_014364.1 34617 36143 D COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: bga:BG0143 hypothetical protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein; outer membrane efflux protein 34617..36143 Spirochaeta smaragdinae DSM 11293 9488107 YP_003801791.1 CDS Spirs_0037 NC_014364.1 36136 37101 D COGs: COG0845 membrane-fusion protein; InterPro IPR006143; KEGG: btu:BT0141 acriflavin resistance periplasmic protein; PFAM: secretion protein HlyD; SPTR: Acriflavin resistance periplasmic protein; TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: Biotin-requiring enzyme; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit 36136..37101 Spirochaeta smaragdinae DSM 11293 9488108 YP_003801792.1 CDS Spirs_0038 NC_014364.1 37116 40325 D COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: bdu:BDU_143 acriflavine resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavine resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family; acriflavin resistance protein 37116..40325 Spirochaeta smaragdinae DSM 11293 9488109 YP_003801793.1 CDS Spirs_0039 NC_014364.1 40322 40618 D KEGG: bre:BRE_141 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 40322..40618 Spirochaeta smaragdinae DSM 11293 9488110 YP_003801794.1 CDS Spirs_0040 NC_014364.1 40681 41802 D COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR003018:IPR003607:IPR006674; KEGG: wsu:WS1630 response regulator; PFAM: metal-dependent phosphohydrolase HD sub domain; GAF domain protein; SMART: GAF domain protein; metal-dependent phosphohydrolase HD region; SPTR: metal dependent phosphohydrolase; PFAM: HD domain; GAF domain; metal dependent phosphohydrolase 40681..41802 Spirochaeta smaragdinae DSM 11293 9488111 YP_003801795.1 CDS Spirs_0041 NC_014364.1 41819 42910 R COGs: COG3621 patatin; InterPro IPR002641; KEGG: cyc:PCC7424_4648 patatin; PFAM: patatin; SPTR: patatin family protein; PFAM: patatin-like phospholipase; patatin complement(41819..42910) Spirochaeta smaragdinae DSM 11293 9488112 YP_003801796.1 CDS Spirs_0042 NC_014364.1 42907 44283 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: amt:Amet_4230 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(42907..44283) Spirochaeta smaragdinae DSM 11293 9488113 YP_003801797.1 CDS Spirs_0043 NC_014364.1 44427 45500 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: bcl:ABC3473 hypothetical protein; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; LacI family transcriptional regulator 44427..45500 Spirochaeta smaragdinae DSM 11293 9488114 YP_003801798.1 CDS Spirs_0044 NC_014364.1 45662 46897 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 45662..46897 Spirochaeta smaragdinae DSM 11293 9488115 YP_003801799.1 CDS Spirs_0045 NC_014364.1 46998 47873 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_0386 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 46998..47873 Spirochaeta smaragdinae DSM 11293 9488116 YP_003801800.1 CDS Spirs_0046 NC_014364.1 47882 48712 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bmq:BMQ_2796 ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 47882..48712 Spirochaeta smaragdinae DSM 11293 9488117 YP_003801801.1 CDS Spirs_0047 NC_014364.1 48721 50745 D COGs: COG1501 alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: sma:SAV_2570 glycosyl hydrolase; PFAM: glycoside hydrolase family 31; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 31; glycoside hydrolase family protein 48721..50745 Spirochaeta smaragdinae DSM 11293 9488118 YP_003801802.1 CDS Spirs_0048 NC_014364.1 50804 51673 D COGs: COG1237 metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: tga:TGAM_1342 metal-dependent hydrolase/oxidoreductase, beta-lactamase family; SPTR: metallo-beta-lactamase domain protein, ; PFAM: metallo-beta-lactamase superfamily; metal-dependent hydrolase/oxidoreductase, beta-lactamase family 50804..51673 Spirochaeta smaragdinae DSM 11293 9488119 YP_003801803.1 CDS Spirs_0049 NC_014364.1 51724 53061 R COGs: COG1113 gamma-aminobutyrate permease and related permease; InterPro IPR004841:IPR002293; KEGG: mem:Memar_1826 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; amino acid permease-associated protein complement(51724..53061) Spirochaeta smaragdinae DSM 11293 9488120 YP_003801804.1 CDS Spirs_0050 NC_014364.1 53132 55048 R COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR013704:IPR007197; KEGG: cth:Cthe_1094 hypothetical protein; PFAM: radical SAM protein; radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM-like protein; PFAM: Domain of unknown function (DUF3362); radical SAM superfamily; radical SAM N-terminal; radical SAM protein complement(53132..55048) Spirochaeta smaragdinae DSM 11293 9488121 YP_003801805.1 CDS Spirs_0051 NC_014364.1 55045 55689 R COGs: COG1428 deoxynucleoside kinase; InterPro IPR002624; KEGG: dge:Dgeo_0101 deoxynucleoside kinase; PFAM: deoxynucleoside kinase; SPTR: deoxynucleoside kinase; PFAM: deoxynucleoside kinase; deoxynucleoside kinase complement(55045..55689) Spirochaeta smaragdinae DSM 11293 9488122 YP_003801806.1 CDS Spirs_0052 NC_014364.1 55750 56901 R COGs: COG1609 transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: aca:ACP_0022 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; family; GntR family transcriptional regulator complement(55750..56901) Spirochaeta smaragdinae DSM 11293 9488123 YP_003801807.1 CDS Spirs_0053 NC_014364.1 57132 58085 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: eok:G2583_4914 periplasmic ribose-binding protein of ABC transporter; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: carbohydrate binding protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 57132..58085 Spirochaeta smaragdinae DSM 11293 9488124 YP_003801808.1 CDS Spirs_0054 NC_014364.1 58172 59704 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR015861:IPR017871; KEGG: ava:Ava_2172 ABC transporter-like; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ribose import ATP-binding protein RbsA; PFAM: ABC transporter; ABC transporter 58172..59704 Spirochaeta smaragdinae DSM 11293 9488125 YP_003801809.1 CDS Spirs_0055 NC_014364.1 59728 60696 D COGs: COG4158 ABC-type sugar transporter permease component; InterPro IPR001851; KEGG: npu:Npun_R5324 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 59728..60696 Spirochaeta smaragdinae DSM 11293 9488126 YP_003801810.1 CDS Spirs_0056 NC_014364.1 60711 62132 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: rxy:Rxyl_2898 xylulokinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 60711..62132 Spirochaeta smaragdinae DSM 11293 9488127 YP_003801811.1 CDS Spirs_0057 NC_014364.1 62189 63106 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495:IPR005467; KEGG: lbf:LBF_2370 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: two-component response regulator; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 62189..63106 Spirochaeta smaragdinae DSM 11293 9488128 YP_003801812.1 CDS Spirs_0058 NC_014364.1 63113 64912 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: cbt:CLH_1795 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(63113..64912) Spirochaeta smaragdinae DSM 11293 9488129 YP_003801813.1 CDS Spirs_0059 NC_014364.1 65000 66766 D COGs: COG0469 pyruvate kinase; InterPro IPR015793:IPR001697:IPR015794:IPR018209; KEGG: pth:PTH_2214 pyruvate kinase; PFAM: pyruvate kinase barrel; pyruvate kinase alpha/beta; PRIAM: pyruvate kinase; SPTR: pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: pyruvate kinase, barrel domain; pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase; pyruvate kinase 65000..66766 Spirochaeta smaragdinae DSM 11293 9488130 YP_003801814.1 CDS Spirs_0060 NC_014364.1 66913 67215 D COGs: COG2151 metal-sulfur cluster biosynthetic protein; InterPro IPR002744:IPR002052; KEGG: sti:Sthe_0635 protein of unknown function DUF59; PFAM: protein of unknown function DUF59; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF59; hypothetical protein 66913..67215 Spirochaeta smaragdinae DSM 11293 9488131 YP_003801815.1 CDS Spirs_0061 NC_014364.1 67234 68040 D COGs: COG0396 ABC-type transporter involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003593:IPR003439:IPR017871; KEGG: gtn:GTNG_2946 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; TIGRFAM: FeS assembly ATPase SufC; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC; FeS assembly ATPase SufC 67234..68040 Spirochaeta smaragdinae DSM 11293 9488132 YP_003801816.1 CDS Spirs_0062 NC_014364.1 68033 69451 D COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR010231:IPR000825; KEGG: ttr:Tter_1698 FeS assembly protein SufB; PFAM: SufBD protein; SPTR: FeS assembly protein SufB; TIGRFAM: FeS assembly protein SufB; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB; FeS assembly protein SufB 68033..69451 Spirochaeta smaragdinae DSM 11293 9488133 YP_003801817.1 CDS Spirs_0063 NC_014364.1 69451 70740 D COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR000825; KEGG: acr:Acry_2270 FeS assembly protein SufD; PFAM: SufBD protein; SPTR: FeS assembly protein SufD; PFAM: Uncharacterized protein family (UPF0051); SufBD protein 69451..70740 Spirochaeta smaragdinae DSM 11293 9488134 YP_003801818.1 CDS Spirs_0064 NC_014364.1 70733 72022 D COGs: COG0520 Selenocysteine lyase; InterPro IPR010970:IPR000192; KEGG: ade:Adeh_0846 SufS subfamily cysteine desulfurase; PFAM: aminotransferase class V; SPTR: cysteine desulfurase, SufS subfamily; TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; SufS subfamily cysteine desulfurase 70733..72022 Spirochaeta smaragdinae DSM 11293 9488135 YP_003801819.1 CDS Spirs_0065 NC_014364.1 72019 72483 D COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: sha:SH2036 hypothetical protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS assembly protein, NifU family; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family; SUF system FeS assembly protein, NifU family 72019..72483 Spirochaeta smaragdinae DSM 11293 9488136 YP_003801820.1 CDS Spirs_0066 NC_014364.1 72493 73500 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: oan:Oant_4373 regulatory protein LacI; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Regulatory protein LacI; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(72493..73500) Spirochaeta smaragdinae DSM 11293 9488137 YP_003801821.1 CDS Spirs_0067 NC_014364.1 73752 74654 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR020625; KEGG: bcl:ABC3607 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 73752..74654 Spirochaeta smaragdinae DSM 11293 9488138 YP_003801822.1 CDS Spirs_0068 NC_014364.1 74694 75659 D COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: bcl:ABC3606 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein 74694..75659 Spirochaeta smaragdinae DSM 11293 9488139 YP_003801823.1 CDS Spirs_0069 NC_014364.1 75729 76175 D KEGG: tle:Tlet_0634 hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctB family; hypothetical protein 75729..76175 Spirochaeta smaragdinae DSM 11293 9488140 YP_003801824.1 CDS Spirs_0070 NC_014364.1 76198 77709 D COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: bcl:ABC3604 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein 76198..77709 Spirochaeta smaragdinae DSM 11293 9488141 YP_003801825.1 CDS Spirs_0071 NC_014364.1 77737 78747 D COGs: COG2376 dihydroxyacetone kinase; InterPro IPR004006; KEGG: oan:Oant_4368 glycerone kinase; PFAM: Dak kinase; PRIAM: glycerone kinase; SPTR: glycerone kinase; PFAM: Dak1 domain; glycerone kinase 77737..78747 Spirochaeta smaragdinae DSM 11293 9488142 YP_003801826.1 CDS Spirs_0072 NC_014364.1 78750 79388 D COGs: COG2376 dihydroxyacetone kinase; InterPro IPR004007; KEGG: oan:Oant_4367 Dak phosphatase; PFAM: Dak phosphatase; SPTR: Dak phosphatase; PFAM: DAK2 domain; Dak phosphatase 78750..79388 Spirochaeta smaragdinae DSM 11293 9488143 YP_003801827.1 CDS Spirs_0073 NC_014364.1 79576 80136 D COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: dsa:Desal_2222 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 79576..80136 Spirochaeta smaragdinae DSM 11293 9488144 YP_003801828.1 CDS Spirs_0074 NC_014364.1 80123 80977 D COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR014284:IPR007627; KEGG: psl:Psta_4074 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 80123..80977 Spirochaeta smaragdinae DSM 11293 9488145 YP_003801829.1 CDS Spirs_0075 NC_014364.1 81057 82031 R InterPro IPR006992; KEGG: bxe:Bxe_A2721 metal-dependent hydrolase; PFAM: amidohydrolase 2; SPTR: Predicted metal-dependent hydrolase; PFAM: Amidohydrolase; amidohydrolase 2 complement(81057..82031) Spirochaeta smaragdinae DSM 11293 9488146 YP_003801830.1 CDS Spirs_0076 NC_014364.1 82046 82996 R InterPro IPR006992; KEGG: bur:Bcep18194_B2954 amidohydrolase 2; PFAM: amidohydrolase 2; SPTR: Amidohydrolase 2; PFAM: Amidohydrolase; amidohydrolase 2 complement(82046..82996) Spirochaeta smaragdinae DSM 11293 9488147 YP_003801831.1 CDS Spirs_0077 NC_014364.1 83108 83692 D COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: bpf:BpOF4_12170 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator (TetR family); PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 83108..83692 Spirochaeta smaragdinae DSM 11293 9488148 YP_003801832.1 CDS Spirs_0078 NC_014364.1 83815 83964 R KEGG: ccv:CCV52592_0501 sensor histidine kinase; SPTR: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; sensor histidine kinase complement(83815..83964) Spirochaeta smaragdinae DSM 11293 9488149 YP_003801833.1 CDS Spirs_0079 NC_014364.1 84057 84623 D COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: rpe:RPE_3675 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 84057..84623 Spirochaeta smaragdinae DSM 11293 9488150 YP_003801834.1 CDS Spirs_0080 NC_014364.1 84638 85978 D COGs: COG0366 glycosidase; InterPro IPR006589:IPR006047; KEGG: hau:Haur_2435 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: uncharacterized protein; PFAM: alpha amylase, catalytic domain; alpha amylase catalytic subunit 84638..85978 Spirochaeta smaragdinae DSM 11293 9488151 YP_003801835.1 CDS Spirs_0081 NC_014364.1 85975 86556 R InterPro IPR001646; KEGG: cli:Clim_1473 pentapeptide repeat protein; SPTR: uncharacterized protein; PFAM: Pentapeptide repeats (8 copies); pentapeptide repeat protein complement(85975..86556) Spirochaeta smaragdinae DSM 11293 9488152 YP_003801836.1 CDS Spirs_0082 NC_014364.1 86655 87179 D COGs: COG1585 membrane protein implicated in regulation of membrane protease activity; InterPro IPR002810; KEGG: tde:TDE1505 hypothetical protein; PFAM: protein of unknown function DUF107; SPTR: membrane protein, ; PFAM: NfeD-like; hypothetical protein 86655..87179 Spirochaeta smaragdinae DSM 11293 9488153 YP_003801837.1 CDS Spirs_0083 NC_014364.1 87220 88134 D COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972:IPR001107; KEGG: tde:TDE0705 SPFH domain-containing protein/band 7 family protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: SPFH domain/Band 7 family protein; PFAM: SPFH domain / Band 7 family; band 7 protein 87220..88134 Spirochaeta smaragdinae DSM 11293 9488154 YP_003801838.1 CDS Spirs_0084 NC_014364.1 88131 89051 D COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001972:IPR001107; KEGG: tde:TDE0704 SPFH domain-containing protein/band 7 family protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: SPFH domain/Band 7 family protein; PFAM: SPFH domain / Band 7 family; band 7 protein 88131..89051 Spirochaeta smaragdinae DSM 11293 9488155 YP_003801839.1 CDS Spirs_0085 NC_014364.1 89242 90681 D COGs: COG1626 Neutral trehalase; InterPro IPR019775; KEGG: tde:TDE0996 hypothetical protein; SPTR: Trehalase; PFAM: Trehalase; hypothetical protein 89242..90681 Spirochaeta smaragdinae DSM 11293 9488156 YP_003801840.1 CDS Spirs_0086 NC_014364.1 90683 91270 R COGs: COG0353 recombinational DNA repair protein (RecF pathway); InterPro IPR000093:IPR006154:IPR015967:IPR006171; KEGG: tde:TDE1549 recombination protein RecR; PFAM: TOPRIM domain protein; Zinc finger C4-type, RecR; SMART: Toprim sub domain protein; SPTR: recombination protein RecR; TIGRFAM: recombination protein RecR; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR; recombination protein RecR complement(90683..91270) Spirochaeta smaragdinae DSM 11293 9488157 YP_003801841.1 CDS Spirs_0087 NC_014364.1 91272 91604 R COGs: COG0718 conserved hypothetical protein; InterPro IPR004401; KEGG: ddf:DEFDS_0142 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: conserved hypothetical protein TIGR00103; hypothetical protein complement(91272..91604) Spirochaeta smaragdinae DSM 11293 9488158 YP_003801842.1 CDS Spirs_0088 NC_014364.1 91601 93346 R COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR001270:IPR012763:IPR003593:IPR003959; KEGG: tde:TDE2586 DNA polymerase III subunits gamma and tau; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: DNA polymerase III gamma and tau subunits, ; TIGRFAM: DNA polymerase III subunits gamma and tau; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III delta' subunit; DNA polymerase III subunits gamma and tau; DNA polymerase III subunits gamma and tau complement(91601..93346) Spirochaeta smaragdinae DSM 11293 9488159 YP_003801843.1 CDS Spirs_0089 NC_014364.1 94079 94924 R COGs: COG0648 endonuclease IV; InterPro IPR001719:IPR012307:IPR018246; KEGG: nis:NIS_0286 endonuclease IV; PFAM: Xylose isomerase domain protein TIM barrel; PRIAM: deoxyribonuclease IV (phage-T(4)-induced); SMART: AP endonuclease family 2; SPTR: Probable endonuclease 4; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1); apurinic endonuclease Apn1 complement(94079..94924) Spirochaeta smaragdinae DSM 11293 9488166 YP_003801844.1 CDS Spirs_0090 NC_014364.1 94928 95251 R KEGG: tet:TTHERM_00046720 TBC domain containing protein; SPTR: TBC domain containing protein; hypothetical protein complement(94928..95251) Spirochaeta smaragdinae DSM 11293 9488167 YP_003801845.1 CDS Spirs_0091 NC_014364.1 95322 96872 D COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076; KEGG: shi:Shel_15100 FAD-dependent dehydrogenase; PFAM: FAD dependent oxidoreductase; SPTR: FAD-dependent dehydrogenase; PFAM: FAD binding domain; FAD dependent oxidoreductase 95322..96872 Spirochaeta smaragdinae DSM 11293 9488168 YP_003801846.1 CDS Spirs_0092 NC_014364.1 96869 97747 R COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: cbc:CbuK_1387 bacterial DNA-binding protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: Bacterial DNA-binding protein; PFAM: Bacterial DNA-binding protein; histone family protein DNA-binding protein complement(96869..97747) Spirochaeta smaragdinae DSM 11293 9488169 YP_003801847.1 CDS Spirs_0093 NC_014364.1 97861 98385 D KEGG: ctp:CTRG_05554 hypothetical protein; SPTR: Whole genome shotgun sequence assembly, scaffold_14; hypothetical protein 97861..98385 Spirochaeta smaragdinae DSM 11293 9488170 YP_003801848.1 CDS Spirs_0094 NC_014364.1 98389 99417 D InterPro IPR006186; KEGG: app:CAP2UW1_3783 metallophosphoesterase; SPTR: metallophosphoesterase; hypothetical protein 98389..99417 Spirochaeta smaragdinae DSM 11293 9488171 YP_003801849.1 CDS Spirs_0095 NC_014364.1 99414 101030 D COGs: COG0515 serine/threonine protein kinase; InterProIPR020635:IPR002290:IPR017442:IPR000719:IPR 008271; KEGG: mxa:MXAN_6317 serine/threonine protein kinase; PFAM: serine/threonine-protein kinase-like domain; SMART: serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; SPTR: serine/threonine protein kinase PksC; PFAM: protein kinase domain; serine/threonine protein kinase 99414..101030 Spirochaeta smaragdinae DSM 11293 9488172 YP_003801850.1 CDS Spirs_0096 NC_014364.1 101044 101919 D InterPro IPR000253; KEGG: rrs:RoseRS_3946 hypothetical protein; PFAM: Forkhead-associated protein; SPTR: uncharacterized protein; PFAM: FHA domain; FHA domain containing protein 101044..101919 Spirochaeta smaragdinae DSM 11293 9488173 YP_003801851.1 CDS Spirs_0097 NC_014364.1 101939 103363 D InterPro IPR002035; KEGG: amt:Amet_1755 von Willebrand factor, type A; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: von Willebrand factor, type A; von Willebrand factor A 101939..103363 Spirochaeta smaragdinae DSM 11293 9488174 YP_003801852.1 CDS Spirs_0098 NC_014364.1 103360 104226 R InterPro IPR000620; KEGG: gau:GAU_0613 hypothetical membrane protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Hypothetical membrane protein; PFAM: EamA-like transporter family; hypothetical protein complement(103360..104226) Spirochaeta smaragdinae DSM 11293 9488175 YP_003801853.1 CDS Spirs_0099 NC_014364.1 104240 105202 R InterPro IPR000086:IPR020084; KEGG: dat:HRM2_01950 MutT family protein, 78-dihydro-8-oxoguanine triphosphatase (8-oxo-dGTPase); PFAM: NUDIX hydrolase; SPTR: MutT family protein, 78-dihydro-8-oxoguanine triphosphatase (8-oxo-dGTPase); PFAM: NUDIX domain; NUDIX hydrolase complement(104240..105202) Spirochaeta smaragdinae DSM 11293 9488176 YP_003801854.1 CDS Spirs_0100 NC_014364.1 105282 106430 D COGs: COG1435 thymidine kinase; KEGG: bdu:BDU_798 thymidine kinase; SPTR: thymidine kinase; PFAM: thymidine kinase; thymidine kinase 105282..106430 Spirochaeta smaragdinae DSM 11293 9488177 YP_003801855.1 CDS Spirs_0101 NC_014364.1 106440 106844 R COGs: COG2703 hemerythrin; InterPro IPR012827:IPR012312:IPR016131; KEGG: dsa:Desal_0057 hemerythrin-like metal-binding protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein complement(106440..106844) Spirochaeta smaragdinae DSM 11293 9488178 YP_003801856.1 CDS Spirs_0102 NC_014364.1 106846 107262 R COGs: COG2703 hemerythrin; InterPro IPR012827:IPR012312; KEGG: gem:GM21_3958 hemerythrin-like metal-binding protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin-like metal-binding protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein complement(106846..107262) Spirochaeta smaragdinae DSM 11293 9488179 YP_003801857.1 CDS Spirs_0103 NC_014364.1 107373 108086 D COGs: COG4912 DNA alkylation repair protein; InterPro IPR014825; KEGG: mma:MM_0566 hypothetical protein; PFAM: DNA alkylation repair enzyme; SPTR: uncharacterized protein; PFAM: DNA alkylation repair enzyme; DNA alkylation repair enzyme 107373..108086 Spirochaeta smaragdinae DSM 11293 9488180 YP_003801858.1 CDS Spirs_0104 NC_014364.1 108090 108626 R COGs: COG3797 conserved hypothetical protein; InterPro IPR012545; KEGG: sna:Snas_5447 hypothetical protein; PFAM: protein of unknown function DUF1697; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1697); hypothetical protein complement(108090..108626) Spirochaeta smaragdinae DSM 11293 9488181 YP_003801859.1 CDS Spirs_0105 NC_014364.1 108623 108964 R InterPro IPR001450:IPR017896; KEGG: dhd:Dhaf_2058 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(108623..108964) Spirochaeta smaragdinae DSM 11293 9488182 YP_003801860.1 CDS Spirs_0106 NC_014364.1 108961 110961 R COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076; KEGG: pen:PSEEN0175 oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Predicted protein; PFAM: domain; FAD binding domain; FAD dependent oxidoreductase complement(108961..110961) Spirochaeta smaragdinae DSM 11293 9488183 YP_003801861.1 CDS Spirs_0108 NC_014364.1 111582 112223 R KEGG: neu:NE2494 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(111582..112223) Spirochaeta smaragdinae DSM 11293 9488185 YP_003801862.1 CDS Spirs_0110 NC_014364.1 112595 113878 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR013108; KEGG: mta:Moth_0460 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(112595..113878) Spirochaeta smaragdinae DSM 11293 9488187 YP_003801863.1 CDS Spirs_0111 NC_014364.1 114950 116146 R COGs: COG0078 ornithine carbamoyltransferase; InterProIPR006130:IPR002082:IPR017702:IPR006132:IPR 006131; KEGG: efa:EF2577 aspartate/ornithine carbamoyltransferase family protein; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: aspartate/ornithine carbamoyltransferase family protein; TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: probable carbamoyltransferase YgeW; carbamoyltransferase YgeW complement(114950..116146) Spirochaeta smaragdinae DSM 11293 9488188 YP_003801864.1 CDS Spirs_0112 NC_014364.1 116187 117647 R COGs: COG0031 cysteine synthase; InterPro IPR001926; KEGG: pmo:Pmob_1727 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: pyridoxal-phosphate dependent enzyme; pyridoxal-5'-phosphate-dependent protein subunit beta complement(116187..117647) Spirochaeta smaragdinae DSM 11293 9488189 YP_003801865.1 CDS Spirs_0113 NC_014364.1 117651 118865 R COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: kol:Kole_2070 M20/DapE family protein YgeY; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: selenium metabolism hydrolase; M20/DapE family protein YgeY; peptidase M20 complement(117651..118865) Spirochaeta smaragdinae DSM 11293 9488190 YP_003801866.1 CDS Spirs_0114 NC_014364.1 119253 119996 D COGs: COG4126 Hydantoin racemase; InterPro IPR015942; KEGG: rpf:Rpic12D_1297 Asp/Glu/hydantoin racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Hydantoin racemase; SPTR: uncharacterized protein; PFAM: Asp/Glu/Hydantoin racemase; Hydantoin racemase 119253..119996 Spirochaeta smaragdinae DSM 11293 9488191 YP_003801867.1 CDS Spirs_0115 NC_014364.1 120206 121609 D COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR011778:IPR006680; KEGG: bcl:ABC3783 phenylhydantoinase; PFAM: amidohydrolase; SPTR: D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; dihydroorotase; dihydropyrimidinase 120206..121609 Spirochaeta smaragdinae DSM 11293 9488192 YP_003801868.1 CDS Spirs_0116 NC_014364.1 121640 122818 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mta:Moth_0710 peptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase M20; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: selenium metabolism hydrolase; peptidase M20 121640..122818 Spirochaeta smaragdinae DSM 11293 9488193 YP_003801869.1 CDS Spirs_0117 NC_014364.1 122799 123008 D KEGG: wsu:WS1642 flagellar biosynthesis regulator FlhF; SPTR: Trypsin type 7; hypothetical protein 122799..123008 Spirochaeta smaragdinae DSM 11293 9488194 YP_003801870.1 CDS Spirs_0118 NC_014364.1 122995 123981 D COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: ter:Tery_3674 basic membrane lipoprotein; PFAM: basic membrane lipoprotein; SPTR: uncharacterized protein; PFAM: Basic membrane protein; basic membrane lipoprotein 122995..123981 Spirochaeta smaragdinae DSM 11293 9488195 YP_003801871.1 CDS Spirs_0119 NC_014364.1 124082 125605 D COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: ctc:CTC00370 sugar transport ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 124082..125605 Spirochaeta smaragdinae DSM 11293 9488196 YP_003801872.1 CDS Spirs_0120 NC_014364.1 125602 126717 D COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: cyt:cce_2447 permease of sugar ABC transporter; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 125602..126717 Spirochaeta smaragdinae DSM 11293 9488197 YP_003801873.1 CDS Spirs_0121 NC_014364.1 126707 127633 D COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: npu:Npun_R4718 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 126707..127633 Spirochaeta smaragdinae DSM 11293 9488198 YP_003801874.1 CDS Spirs_0122 NC_014364.1 127941 128690 D COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: btl:BALH_3421 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulators; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator 127941..128690 Spirochaeta smaragdinae DSM 11293 9488199 YP_003801875.1 CDS Spirs_0124 NC_014364.1 128879 129154 D InterPro IPR002514; KEGG: cth:Cthe_0590 transposase IS3/IS911; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911; PFAM: transposase; transposase IS3/IS911 family protein 128879..129154 Spirochaeta smaragdinae DSM 11293 9488201 YP_003801876.1 CDS Spirs_0125 NC_014364.1 129183 129998 D COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: glo:Glov_3665 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain; Integrase catalytic subunit 129183..129998 Spirochaeta smaragdinae DSM 11293 9488202 YP_003801877.1 CDS Spirs_0126 NC_014364.1 130540 131487 R KEGG: cdl:CDR20291_0238 flagellar cap protein; SPTR: flagellar cap protein; hypothetical protein complement(130540..131487) Spirochaeta smaragdinae DSM 11293 9488203 YP_003801878.1 CDS Spirs_0127 NC_014364.1 131721 132242 R COGs: COG1247 Sortase and related acyltransferase; InterPro IPR000182; KEGG: rcu:RCOM_1843230 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase complement(131721..132242) Spirochaeta smaragdinae DSM 11293 9488204 YP_003801879.1 CDS Spirs_0128 NC_014364.1 132244 133020 R COGs: COG0627 esterase; InterPro IPR000801; KEGG: bbe:BBR47_31170 hypothetical protein; PFAM: esterase; SPTR: uncharacterized protein; PFAM: esterase; esterase complement(132244..133020) Spirochaeta smaragdinae DSM 11293 9488205 YP_003801880.1 CDS Spirs_0129 NC_014364.1 133393 134100 D InterPro IPR018060:IPR000005; KEGG: ppf:Pput_2324 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 133393..134100 Spirochaeta smaragdinae DSM 11293 9488206 YP_003801881.1 CDS Spirs_0130 NC_014364.1 134162 134563 D InterPro IPR018988:IPR017021; KEGG: cdl:CDR20291_1132 hypothetical protein; PFAM: protein of unknown function DUF2000; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2000); hypothetical protein 134162..134563 Spirochaeta smaragdinae DSM 11293 9488207 YP_003801882.1 CDS Spirs_0131 NC_014364.1 134625 135299 R COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: ckr:CKR_0542 hypothetical protein; PFAM: YheO domain protein; SPTR: uncharacterized protein; PFAM: YheO-like PAS domain; YheO domain-containing protein complement(134625..135299) Spirochaeta smaragdinae DSM 11293 9488208 YP_003801883.1 CDS Spirs_0132 NC_014364.1 135466 136797 R COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: ctc:CTC01190 sodium-dependent amino acid transporter (proline, tryptophan); PFAM: sodium:neurotransmitter symporter; SPTR: transporter; PFAM: Sodium:neurotransmitter symporter family; sodium:neurotransmitter symporter complement(135466..136797) Spirochaeta smaragdinae DSM 11293 9488209 YP_003801884.1 CDS Spirs_0133 NC_014364.1 136871 138253 R COGs: COG3033 tryptophanase; InterPro IPR001597:IPR011166:IPR018176; KEGG: ctc:CTC01509 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: tryptophanase; SPTR: tryptophanase; PFAM: beta-eliminating lyase; TIGRFAM: tryptophanase, leader peptide-associated; tryptophanase complement(136871..138253) Spirochaeta smaragdinae DSM 11293 9488210 YP_003801885.1 CDS Spirs_0134 NC_014364.1 138283 138666 R COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR006056:IPR006175:IPR019897; KEGG: tde:TDE2069 endoribonuclease L-PSP, PFAM: endoribonuclease L-PSP; SPTR: translation initiation inhibitor protein; TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; endoribonuclease L-PSP complement(138283..138666) Spirochaeta smaragdinae DSM 11293 9488211 YP_003801886.1 CDS Spirs_0135 NC_014364.1 138846 140063 R hypothetical protein complement(138846..140063) Spirochaeta smaragdinae DSM 11293 9488212 YP_003801887.1 CDS Spirs_0136 NC_014364.1 140202 140744 R COGs: COG0717 deoxycytidine deaminase; InterPro IPR011962; KEGG: cac:CAC0025 deoxycytidine triphosphate deaminase; SPTR: deoxycytidine triphosphate deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; TIGRFAM: deoxycytidine triphosphate deaminase; deoxycytidine triphosphate deaminase complement(140202..140744) Spirochaeta smaragdinae DSM 11293 9488213 YP_003801888.1 CDS Spirs_0137 NC_014364.1 140833 141891 D InterPro IPR006675:IPR006674; KEGG: sus:acid_4618 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SPTR: metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase 140833..141891 Spirochaeta smaragdinae DSM 11293 9488214 YP_003801889.1 CDS Spirs_0138 NC_014364.1 142012 143247 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR003593:IPR002078; KEGG: dae:Dtox_1013 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; SMART: response regulator receiver; ATPase AAA; SPTR: Two component, sigma54 specific, Fis family transcriptional regulator; PFAM: Response regulator receiver domain; Sigma-54 interaction domain; Fis family transcriptional regulator 142012..143247 Spirochaeta smaragdinae DSM 11293 9488215 YP_003801890.1 CDS Spirs_0139 NC_014364.1 143261 143803 R KEGG: tgo:TGME49_018300 zinc finger (CCCH type) protein, SPTR: Filamentous haemagglutinin family N-terminal domain protein; hypothetical protein complement(143261..143803) Spirochaeta smaragdinae DSM 11293 9488216 YP_003801891.1 CDS Spirs_0140 NC_014364.1 143872 144423 D COGs: COG1366 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658:IPR002645; KEGG: tde:TDE2083 anti-anti-sigma factor; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 143872..144423 Spirochaeta smaragdinae DSM 11293 9488217 YP_003801892.1 CDS Spirs_0141 NC_014364.1 144429 144800 D KEGG: scl:sce5471 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 144429..144800 Spirochaeta smaragdinae DSM 11293 9488218 YP_003801893.1 CDS Spirs_0142 NC_014364.1 144822 145508 D COGs: COG1842 Phage shock protein A (IM30) suppresses sigma54-dependent transcription; InterPro IPR007157; KEGG: hoh:Hoch_0487 phage shock protein A, PspA; PFAM: PspA/IM30 family protein; SPTR: Phage shock protein A, PspA; PFAM: PspA/IM30 family; phage shock protein A, PspA 144822..145508 Spirochaeta smaragdinae DSM 11293 9488219 YP_003801894.1 CDS Spirs_0143 NC_014364.1 145492 146151 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001867; KEGG: aco:Amico_1683 two component transcriptional regulator, winged helix family; PFAM: transcriptional regulator; SPTR: Two component transcriptional regulator, winged helix family; PFAM: transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 145492..146151 Spirochaeta smaragdinae DSM 11293 9488220 YP_003801895.1 CDS Spirs_0144 NC_014364.1 146453 147415 D KEGG: rop:ROP_00830 cytochrome C oxidase subunit I; SPTR: cytochrome C oxidase subunit I; hypothetical protein 146453..147415 Spirochaeta smaragdinae DSM 11293 9488221 YP_003801896.1 CDS Spirs_0145 NC_014364.1 147408 149150 D InterPro IPR019734:IPR013026; KEGG: tde:TDE0867 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 147408..149150 Spirochaeta smaragdinae DSM 11293 9488222 YP_003801897.1 CDS Spirs_0146 NC_014364.1 149143 149604 D InterPro IPR001623; KEGG: tau:Tola_2364 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: heat shock protein DnaJ domain protein; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 149143..149604 Spirochaeta smaragdinae DSM 11293 9488223 YP_003801898.1 CDS Spirs_0147 NC_014364.1 149601 150887 R COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR005750:IPR001986; KEGG: tde:TDE0641 UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; UDP-N-acetylglucosamine1- carboxyvinyltransferase complement(149601..150887) Spirochaeta smaragdinae DSM 11293 9488224 YP_003801899.1 CDS Spirs_0148 NC_014364.1 150935 152191 R InterPro IPR018247; KEGG: dse:Dsec_GM19185 GM19185 gene product from transcript GM19185-RA; SPTR: uncharacterized protein; hypothetical protein complement(150935..152191) Spirochaeta smaragdinae DSM 11293 9488225 YP_003801900.1 CDS Spirs_0149 NC_014364.1 152254 152700 D InterPro IPR007313; KEGG: sfr:Sfri_3664 FxsA cytoplasmic membrane protein; PFAM: FxsA cytoplasmic membrane protein; SPTR: membrane protein FxsA (Suppressor of F exclusion of phage T7); PFAM: FxsA cytoplasmic membrane protein; FxsA cytoplasmic membrane protein 152254..152700 Spirochaeta smaragdinae DSM 11293 9488226 YP_003801901.1 CDS Spirs_0150 NC_014364.1 152701 153447 R COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: tde:TDE1876 WecB/TagA/CpsF family glycosyl transferase; PFAM: glycosyl transferase WecB/TagA/CpsF; SPTR: glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: glycosyl transferase, WecB/TagA/CpsF family; PFAM: glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family; WecB/TagA/CpsF family glycosyl transferase complement(152701..153447) Spirochaeta smaragdinae DSM 11293 9488227 YP_003801902.1 CDS Spirs_0151 NC_014364.1 153444 154262 R COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: adg:Adeg_0610 protein of unknown function DUF558; PFAM: protein of unknown function DUF558; SPTR: RNA methyltransferase family protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family; hypothetical protein complement(153444..154262) Spirochaeta smaragdinae DSM 11293 9488228 YP_003801903.1 CDS Spirs_0152 NC_014364.1 154273 154677 R COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: hor:Hore_00760 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: conserved hypothetical protein TIGR00149; hypothetical protein complement(154273..154677) Spirochaeta smaragdinae DSM 11293 9488229 YP_003801904.1 CDS Spirs_0153 NC_014364.1 154674 156176 R COGs: COG0793 Periplasmic protease; InterPro IPR004447:IPR001478:IPR005151; KEGG: bga:BG0359 carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; SPTR: carboxy--processing protease; TIGRFAM: carboxyl-terminal protease; PFAM: peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc); carboxyl-terminal protease complement(154674..156176) Spirochaeta smaragdinae DSM 11293 9488230 YP_003801905.1 CDS Spirs_0154 NC_014364.1 156266 156727 D KEGG: cla:Cla_0909 sodium-dependent transporter (SNF family); SPTR: transporter; hypothetical protein 156266..156727 Spirochaeta smaragdinae DSM 11293 9488231 YP_003801906.1 CDS Spirs_0155 NC_014364.1 156728 157870 D COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tde:TDE1397 flagellar synthesis regulator FleN, PFAM: cobyrinic acid ac-diamide synthase; SPTR: ATP-binding protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase 156728..157870 Spirochaeta smaragdinae DSM 11293 9488232 YP_003801907.1 CDS Spirs_0156 NC_014364.1 157889 160840 D COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: tde:TDE1398 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF342); hypothetical protein 157889..160840 Spirochaeta smaragdinae DSM 11293 9488233 YP_003801908.1 CDS Spirs_0157 NC_014364.1 160837 161784 D COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: tde:TDE1399 prolipoprotein diacylglyceryl transferase; PFAM: prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase; prolipoprotein diacylglyceryl transferase 160837..161784 Spirochaeta smaragdinae DSM 11293 9488234 YP_003801909.1 CDS Spirs_0158 NC_014364.1 161842 162195 D InterPro IPR008207; KEGG: srm:SRM_02645 conserved hypothetical protein containing Hpt domain; PFAM: Hpt domain protein; SPTR: Probable sensor/response hybrid, ; PFAM: Hpt domain; Hpt protein 161842..162195 Spirochaeta smaragdinae DSM 11293 9488235 YP_003801910.1 CDS Spirs_0159 NC_014364.1 162200 164248 D COGs: COG3345 alpha-galactosidase; KEGG: shi:Shel_06470 alpha-galactosidase; SPTR: uncharacterized protein; PFAM: Melibiase; alpha-galactosidase 162200..164248 Spirochaeta smaragdinae DSM 11293 9488236 YP_003801911.1 CDS Spirs_0160 NC_014364.1 164351 165319 D COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR000943:IPR014284:IPR009042:IPR007627:IPR 007624:IPR007630; KEGG: tcu:Tcur_3197 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 3 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 164351..165319 Spirochaeta smaragdinae DSM 11293 9488237 YP_003801912.1 CDS Spirs_0161 NC_014364.1 165410 165775 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: gsu:GSU1289 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Chemotaxis protein CheY; PFAM: Response regulator receiver domain; response regulator receiver protein 165410..165775 Spirochaeta smaragdinae DSM 11293 9488238 YP_003801913.1 CDS Spirs_0162 NC_014364.1 165785 166672 R COGs: COG2215 ABC-type uncharacterized transporter permease; InterPro IPR011541; KEGG: dap:Dacet_2269 high-affinity nickel-transporter; PFAM: high-affinity nickel-transporter; SPTR: High-affinity nickel-transporter; PFAM: High-affinity nickel-transporter; high-affinity nickel-transporter complement(165785..166672) Spirochaeta smaragdinae DSM 11293 9488239 YP_003801914.1 CDS Spirs_0163 NC_014364.1 166684 167337 R COGs: COG3683 ABC-type uncharacterized transporter periplasmic component; InterPro IPR010412; KEGG: tde:TDE0115 hypothetical protein; PFAM: protein of unknown function DUF1007; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1007); hypothetical protein complement(166684..167337) Spirochaeta smaragdinae DSM 11293 9488240 YP_003801915.1 CDS Spirs_0164 NC_014364.1 167360 169501 R COGs: COG0370 Fe2+ transporter protein B; InterProIPR005225:IPR003373:IPR002917:IPR011619:IPR 011642:IPR011640; KEGG: pgi:PG1294 ferrous iron transporter B; PFAM: Ferrous iron transport protein B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; SPTR: Ferrous iron transporter B; TIGRFAM: ferrous iron transporter B; small GTP-binding protein; PFAM: Ferrous iron transporter B; Ferrous iron transporter B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain; ferrous iron transporter B complement(167360..169501) Spirochaeta smaragdinae DSM 11293 9488241 YP_003801916.1 CDS Spirs_0165 NC_014364.1 169501 169779 R COGs: COG1918 Fe2+ transporter protein A; InterPro IPR007167; KEGG: dat:HRM2_10920 Fur; PFAM: FeoA family protein; SPTR: Fur; PFAM: FeoA domain; FeoA family protein complement(169501..169779) Spirochaeta smaragdinae DSM 11293 9488242 YP_003801917.1 CDS Spirs_0166 NC_014364.1 170022 172286 D COGs: COG0620 methionine synthase II (cobalamin-independent); InterPro IPR006276:IPR013215:IPR002629; KEGG: drm:Dred_1751 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; PFAM: methionine synthase vitamin-B12 independent; Cobalamin-independent synthase MetE domain protein; PRIAM:5-methyltetrahydropteroyltriglutamate--homocy steineS-methyltransferase; SPTR:5-methyltetrahydropteroyltriglutamate--homocys teinemethyltransferase; TIGRFAM:5-methyltetrahydropteroyltriglutamate/homoc ysteineS-methyltransferase; PFAM: Cobalamin-independent synthase, N-terminal domain; Cobalamin-independent synthase, Catalytic domain; TIGRFAM: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase; 5- methyltetrahydropteroyltriglutamate/homocysteine S-methyltransferase 170022..172286 Spirochaeta smaragdinae DSM 11293 9488243 YP_003801918.1 CDS Spirs_0167 NC_014364.1 172378 172701 D InterPro IPR007167; KEGG: iho:Igni_1229 FeoA family protein; PFAM: FeoA family protein; SPTR: FeoA family protein; PFAM: FeoA domain; FeoA family protein 172378..172701 Spirochaeta smaragdinae DSM 11293 9488244 YP_003801919.1 CDS Spirs_0168 NC_014364.1 172799 173035 D COGs: COG1918 Fe2+ transporter protein A; InterPro IPR007167; KEGG: alv:Alvin_1526 FeoA family protein; PFAM: FeoA family protein; SPTR: FeoA family protein; PFAM: FeoA domain; FeoA family protein 172799..173035 Spirochaeta smaragdinae DSM 11293 9488245 YP_003801920.1 CDS Spirs_0169 NC_014364.1 173032 175332 D COGs: COG0370 Fe2+ transporter protein B; InterProIPR006073:IPR005225:IPR003373:IPR002917:IPR 011619:IPR011642:IPR011640; KEGG: cpb:Cphamn1_0623 ferrous iron transport protein B; PFAM: Ferrous iron transporter B domain protein; GTP-binding protein HSR1-related; nucleoside recognition domain protein; Ferrous iron transport B domain protein; SPTR: Ferrous iron transporter B; TIGRFAM: ferrous iron transporter B; small GTP-binding protein; PFAM: Ferrous iron transporter B; Ferrous iron transporter B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain; ferrous iron transporter B 173032..175332 Spirochaeta smaragdinae DSM 11293 9488246 YP_003801921.1 CDS Spirs_0170 NC_014364.1 175463 175849 D InterPro IPR018594; KEGG: bfs:BF2690 hypothetical protein; PFAM: Domain of unknown function DUF2023; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2023); hypothetical protein 175463..175849 Spirochaeta smaragdinae DSM 11293 9488247 YP_003801922.1 CDS Spirs_0171 NC_014364.1 175886 176524 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006675:IPR003607:IPR006674; KEGG: tex:Teth514_1141 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase complement(175886..176524) Spirochaeta smaragdinae DSM 11293 9488248 YP_003801923.1 CDS Spirs_0172 NC_014364.1 176646 177143 D COGs: COG0716 Flavodoxins; InterPro IPR001094:IPR010086:IPR008254:IPR001226; KEGG: paa:Paes_0557 flavodoxin; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavodoxin; TIGRFAM: flavodoxin; PFAM: Flavodoxin; TIGRFAM: flavodoxin, long chain; flavodoxin 176646..177143 Spirochaeta smaragdinae DSM 11293 9488249 YP_003801924.1 CDS Spirs_0173 NC_014364.1 177237 178136 R COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388:IPR019758; KEGG: ctc:CTC00743 anaerobic cobalt chelatase CbiK; PFAM: anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Anaerobic cobalt chelatase cbiK; PFAM: Cobalt chelatase (CbiK); Sirohydrochlorin cobaltochelatase complement(177237..178136) Spirochaeta smaragdinae DSM 11293 9488250 YP_003801925.1 CDS Spirs_0174 NC_014364.1 178164 180140 R COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: cts:Ctha_2253 TonB-dependent receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TonB-dependent receptor complement(178164..180140) Spirochaeta smaragdinae DSM 11293 9488251 YP_003801926.1 CDS Spirs_0175 NC_014364.1 180140 180976 R KEGG: kko:Kkor_2439 Na-Ca exchanger/integrin-beta4; SPTR: uncharacterized protein; hypothetical protein complement(180140..180976) Spirochaeta smaragdinae DSM 11293 9488252 YP_003801927.1 CDS Spirs_0176 NC_014364.1 181581 182609 R COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR017846:IPR003200:IPR000209; KEGG: fno:Fnod_1365 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase; PFAM: phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; nicotinate-nucleotide/dimethylbenzimidazole phosphoribosyltransferase complement(181581..182609) Spirochaeta smaragdinae DSM 11293 9488253 YP_003801928.1 CDS Spirs_0177 NC_014364.1 182606 183748 R COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR004838; KEGG: dev:DhcVS_593 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; class I and II aminotransferase complement(182606..183748) Spirochaeta smaragdinae DSM 11293 9488254 YP_003801929.1 CDS Spirs_0178 NC_014364.1 183738 184700 R COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: det:DET0688 cobalamin biosynthesis protein CobD; PFAM: cobalamin biosynthesis protein CbiB; SPTR: Cobalamin biosynthesis protein CobD; TIGRFAM: cobalamin biosynthesis protein CobD; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD; cobalamin biosynthesis protein CobD complement(183738..184700) Spirochaeta smaragdinae DSM 11293 9488255 YP_003801930.1 CDS Spirs_0179 NC_014364.1 184697 186169 R COGs: COG1492 Cobyric acid synthase; InterPro IPR004459:IPR002586:IPR011698:IPR017929; KEGG: deg:DehalGT_0781 cobyric acid synthase CobQ; PFAM: CobB/CobQ domain protein glutamine amidotransferase; cobyrinic acid ac-diamide synthase; SPTR: Cobyric acid synthase CobQ; TIGRFAM: cobyric acid synthase CobQ; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ; cobyric acid synthase CobQ complement(184697..186169) Spirochaeta smaragdinae DSM 11293 9488256 YP_003801931.1 CDS Spirs_0180 NC_014364.1 186599 187630 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: aoe:Clos_0318 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 186599..187630 Spirochaeta smaragdinae DSM 11293 9488257 YP_003801932.1 CDS Spirs_0181 NC_014364.1 187627 188652 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: aoe:Clos_0319 transporter permease; PFAM: transporter permease; SPTR: transport system permease; PFAM: FecCD transport family; transporter permease 187627..188652 Spirochaeta smaragdinae DSM 11293 9488258 YP_003801933.1 CDS Spirs_0182 NC_014364.1 188642 189424 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: aoe:Clos_0320 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter 188642..189424 Spirochaeta smaragdinae DSM 11293 9488259 YP_003801934.1 CDS Spirs_0183 NC_014364.1 189424 190920 D COGs: COG1797 cobyrinic acid a c-diamide synthase; InterPro IPR004484:IPR002586:IPR011698:IPR017929; KEGG: adg:Adeg_0183 cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid ac-diamide synthase; CobB/CobQ domain protein glutamine amidotransferase; SPTR: cobyrinic acid a,c-diamide synthase; TIGRFAM: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase; cobyrinic acid a,c-diamide synthase 189424..190920 Spirochaeta smaragdinae DSM 11293 9488260 YP_003801935.1 CDS Spirs_0184 NC_014364.1 190910 191554 D COGs: COG2082 precorrin isomerase; InterPro IPR003722; KEGG: scl:sce0238 hypothetical protein; PFAM: precorrin-8X methylmutase CbiC/CobH; SPTR: precorrin-8X methylmutase CbiC/CobH; PFAM: precorrin-8X methylmutase; precorrin-8X methylmutase CbiC/CobH 190910..191554 Spirochaeta smaragdinae DSM 11293 9488261 YP_003801936.1 CDS Spirs_0185 NC_014364.1 191557 192696 D COGs: COG1903 Cobalamin biosynthesis protein CbiD; InterPro IPR002748; KEGG: pth:PTH_0951 cobalamin biosynthesis protein; PFAM: cobalamin (vitamin B12) biosynthesis CbiD protein; SPTR: Cobalamin biosynthesis protein CbiD; TIGRFAM: cobalamin biosynthesis protein CbiD; PFAM: CbiD; TIGRFAM: cobalamin biosynthesis protein CbiD; cobalamin biosynthesis protein CbiD 191557..192696 Spirochaeta smaragdinae DSM 11293 9488262 YP_003801937.1 CDS Spirs_0186 NC_014364.1 192693 193367 D COGs: COG2241 precorrin-6B methylase 1; KEGG: cac:CAC0584 precorrin-6B methylase 1 CobL1/CbiE; SPTR: precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6B methylase 1 192693..193367 Spirochaeta smaragdinae DSM 11293 9488263 YP_003801938.1 CDS Spirs_0187 NC_014364.1 193364 194140 D COGs: COG2875 precorrin-4 methylase; InterPro IPR006362:IPR000878:IPR003043; KEGG: mta:Moth_1092 precorrin-4 C11-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; PRIAM: precorrin-4 C(11)-methyltransferase; SPTR: precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-4 C11-methyltransferase; precorrin-4 C11-methyltransferase 193364..194140 Spirochaeta smaragdinae DSM 11293 9488264 YP_003801939.1 CDS Spirs_0188 NC_014364.1 194137 195780 D COGs: COG1010 precorrin-3B methylase; InterPro IPR006363:IPR002750:IPR000878; KEGG: rca:Rcas_0637 precorrin-3B C17-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein; SPTR: precorrin-3B C17-methyltransferase; TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Cobalamin synthesis G C-terminus; Tetrapyrrole (Corrin/Porphyrin) methylases; Cobalamin synthesis G N-terminal; TIGRFAM: precorrin-3B C17-methyltransferase; precorrin-3B C17-methyltransferase 194137..195780 Spirochaeta smaragdinae DSM 11293 9488265 YP_003801940.1 CDS Spirs_0189 NC_014364.1 195770 196036 D COGs: COG2158 Uncharacterized protein containing a Zn-finger-like domain; InterPro IPR007212; KEGG: dsa:Desal_0255 cysteine-rich small domain protein; PFAM: cysteine-rich small domain; SPTR: cysteine-rich small domain protein; PFAM: cysteine-rich small domain; cysteine-rich small domain-containing protein 195770..196036 Spirochaeta smaragdinae DSM 11293 9488266 YP_003801941.1 CDS Spirs_0190 NC_014364.1 196042 196887 D COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: drm:Dred_2191 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase 196042..196887 Spirochaeta smaragdinae DSM 11293 9488267 YP_003801942.1 CDS Spirs_0191 NC_014364.1 197004 197432 D InterPro IPR002850:IPR002716; KEGG: cyc:PCC7424_2307 twitching motility protein PilT; PFAM: twitching motility protein PilT; SPTR: twitching motility protein PilT; PFAM: PIN domain; TIGRFAM: conserved hypothetical protein TIGR00305; twitching motility protein PilT 197004..197432 Spirochaeta smaragdinae DSM 11293 9488268 YP_003801943.1 CDS Spirs_0192 NC_014364.1 197429 197662 D InterPro IPR002145; KEGG: srm:SRM_00772 hypothetical protein; PFAM: CopG family transcriptional regulator; SPTR: CopG family transcriptional regulator; PFAM: Ribbon-helix-helix protein, copG family; CopG family transcriptional regulator 197429..197662 Spirochaeta smaragdinae DSM 11293 9488269 YP_003801944.1 CDS Spirs_0193 NC_014364.1 197713 198450 R COGs: COG2243 precorrin-2 methylase; InterPro IPR006364:IPR000878:IPR012382; KEGG: cvi:CV_1565 precorrin-2 C20-methyltransferase; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: precorrin-2 C20-methylase; TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: precorrin-2 C20-methyltransferase; precorrin-2 C20-methyltransferase complement(197713..198450) Spirochaeta smaragdinae DSM 11293 9488270 YP_003801945.1 CDS Spirs_0194 NC_014364.1 198520 199368 R COGs: COG1108 ABC-type Mn2+/Zn2+ transporters permeases; InterPro IPR001626; KEGG: pca:Pcar_3024 ABC-type transport system, permease; PFAM: ABC transporter; SPTR: ABC-type transport system, permease; PFAM: ABC 3 transport family; ABC transporter complement(198520..199368) Spirochaeta smaragdinae DSM 11293 9488271 YP_003801946.1 CDS Spirs_0195 NC_014364.1 199362 200171 R COGs: COG1121 ABC-type Mn/Zn transporters ATPase component; InterPro IPR003593:IPR003439:IPR017871:IPR018184; KEGG: pca:Pcar_3025 ABC-type transporter, ATP binding component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(199362..200171) Spirochaeta smaragdinae DSM 11293 9488272 YP_003801947.1 CDS Spirs_0196 NC_014364.1 200171 201127 R COGs: COG0803 ABC-type metal ion transporter periplasmic component/surface adhesin; InterPro IPR006127; KEGG: dal:Dalk_1551 periplasmic solute binding protein; PFAM: periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family; periplasmic solute binding protein complement(200171..201127) Spirochaeta smaragdinae DSM 11293 9488273 YP_003801948.1 CDS Spirs_0197 NC_014364.1 201102 201392 R KEGG: hmg:100209601 similar to Zinc finger protein 418; SPTR: uncharacterized protein; hypothetical protein complement(201102..201392) Spirochaeta smaragdinae DSM 11293 9488274 YP_003801949.1 CDS Spirs_0198 NC_014364.1 201481 202368 R COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119:IPR017871; KEGG: ere:EUBREC_1090 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator complement(201481..202368) Spirochaeta smaragdinae DSM 11293 9488275 YP_003801950.1 CDS Spirs_0199 NC_014364.1 202501 202911 D KEGG: ccu:Ccur_10090 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 202501..202911 Spirochaeta smaragdinae DSM 11293 9488276 YP_003801951.1 CDS Spirs_0200 NC_014364.1 203035 204087 D InterPro IPR001509; KEGG: gym:GYMC10_0509 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD dependent epimerase/dehydratase family protein; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 203035..204087 Spirochaeta smaragdinae DSM 11293 9488277 YP_003801952.1 CDS Spirs_0201 NC_014364.1 204099 205157 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR002136; KEGG: rba:RB7999 hypothetical protein; PFAM: dihydrodipicolinate synthetase; ribosomal protein L4/L1e; SPTR: uncharacterized protein; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 204099..205157 Spirochaeta smaragdinae DSM 11293 9488278 YP_003801953.1 CDS Spirs_0202 NC_014364.1 205170 206381 D COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: phe:Phep_1689 natural resistance-associated macrophage protein; PFAM: natural resistance-associated macrophage protein; SPTR: uncharacterized protein; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters; natural resistance-associated macrophage protein 205170..206381 Spirochaeta smaragdinae DSM 11293 9488279 YP_003801954.1 CDS Spirs_0203 NC_014364.1 206388 207074 D COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: reu:Reut_A1048 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 206388..207074 Spirochaeta smaragdinae DSM 11293 9488280 YP_003801955.1 CDS Spirs_0204 NC_014364.1 207078 208277 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR010169:IPR002933:IPR011650:IPR001261; KEGG: bid:Bind_1040 acetylornithine deacetylase (ArgE); PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: acetylornithine deacetylase (ArgE); TIGRFAM: acetylornithine deacetylase (ArgE); PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: acetylornithine deacetylase (ArgE); acetylornithine deacetylase ArgE 207078..208277 Spirochaeta smaragdinae DSM 11293 9488281 YP_003801956.1 CDS Spirs_0205 NC_014364.1 208342 209445 D KEGG: sus:acid_7828 peptidase M14, carboxypeptidase A; SPTR: glycoprotein B; hypothetical protein 208342..209445 Spirochaeta smaragdinae DSM 11293 9488282 YP_003801957.1 CDS Spirs_0206 NC_014364.1 209438 211105 D InterPro IPR002110:IPR020683; KEGG: afv:AFLA_025240 ankyrin repeat-containing protein, PFAM: ankyrin; SMART: ankyrin; SPTR: ankyrin repeat-containing protein, ; PFAM: ankyrin repeat; ankyrin 209438..211105 Spirochaeta smaragdinae DSM 11293 9488283 YP_003801958.1 CDS Spirs_0207 NC_014364.1 211015 211278 R KEGG: cac:CAC1032 transcriptional regulator; SPTR: AsnC family transcriptional regulator; PFAM: FeoC like transcriptional regulator; hypothetical protein complement(211015..211278) Spirochaeta smaragdinae DSM 11293 9488284 YP_003801959.1 CDS Spirs_0208 NC_014364.1 211335 211826 D InterPro IPR005358:IPR017969; KEGG: sga:GALLO_0915 hypothetical protein; PFAM: protein of unknown function UPF0153; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153); hypothetical protein 211335..211826 Spirochaeta smaragdinae DSM 11293 9488285 YP_003801960.1 CDS Spirs_0209 NC_014364.1 211823 212923 R COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR018370; KEGG: amc:MADE_00483 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; adenylate/guanylate cyclase complement(211823..212923) Spirochaeta smaragdinae DSM 11293 9488286 YP_003801961.1 CDS Spirs_0210 NC_014364.1 212996 213250 D KEGG: slt:Slit_1635 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 212996..213250 Spirochaeta smaragdinae DSM 11293 9488287 YP_003801962.1 CDS Spirs_0211 NC_014364.1 213253 215031 D COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: bth:BT_2743 aminopeptidase; PFAM: peptidase M24; creatinase; SPTR: uncharacterized protein; PFAM: metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; peptidase M24 213253..215031 Spirochaeta smaragdinae DSM 11293 9488288 YP_003801963.1 CDS Spirs_0212 NC_014364.1 215034 215990 D COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: kol:Kole_0844 cation diffusion facilitator family transporter; PFAM: cation efflux protein; SPTR: Cation diffusion facilitator family transporter; TIGRFAM: cation diffusion facilitator family transporter; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter; cation diffusion facilitator family transporter 215034..215990 Spirochaeta smaragdinae DSM 11293 9488289 YP_003801964.1 CDS Spirs_0213 NC_014364.1 216028 217680 D COGs: COG0696 phosphoglyceromutase; InterPro IPR005995:IPR011258:IPR006124; KEGG: mca:MCA0753 phosphoglyceromutase; PFAM: BPG-independent PGAM domain protein; metalloenzyme domain protein; PRIAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; TIGRFAM: phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent 216028..217680 Spirochaeta smaragdinae DSM 11293 9488290 YP_003801965.1 CDS Spirs_0214 NC_014364.1 217731 218495 R COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: cbt:CLH_0701 deoxyribose operon repressor; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator complement(217731..218495) Spirochaeta smaragdinae DSM 11293 9488291 YP_003801966.1 CDS Spirs_0215 NC_014364.1 218708 219700 D COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: cro:ROD_24811 ABC transporter substrate-binding protein; SPTR: ABC transporter substrate-binding protein; PFAM: family; ABC transporter substrate-binding protein 218708..219700 Spirochaeta smaragdinae DSM 11293 9488292 YP_003801967.1 CDS Spirs_0216 NC_014364.1 219776 221278 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: rle:pRL80086 ATP-binding component of ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP binding protein; PFAM: ABC transporter; ABC transporter 219776..221278 Spirochaeta smaragdinae DSM 11293 9488293 YP_003801968.1 CDS Spirs_0217 NC_014364.1 221290 222297 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: cro:ROD_24831 ABC transporter membrane protein; PFAM: inner-membrane translocator; SPTR: ribose/xylose/arabinose/galactoside ABC-type transport systems permease 2; PFAM: Branched-chain amino acid transport system / permease; inner-membrane translocator 221290..222297 Spirochaeta smaragdinae DSM 11293 9488294 YP_003801969.1 CDS Spirs_0218 NC_014364.1 222297 223274 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: spe:Spro_4696 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 222297..223274 Spirochaeta smaragdinae DSM 11293 9488295 YP_003801970.1 CDS Spirs_0219 NC_014364.1 223288 224763 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: ttr:Tter_2252 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 223288..224763 Spirochaeta smaragdinae DSM 11293 9488296 YP_003801971.1 CDS Spirs_0220 NC_014364.1 224839 225072 R KEGG: ton:TON_0294 hypothetical protein Plut_1211; SPTR: Predicted protein; hypothetical protein complement(224839..225072) Spirochaeta smaragdinae DSM 11293 9488297 YP_003801972.1 CDS Spirs_0221 NC_014364.1 225069 225572 R InterPro IPR005018:IPR013050; KEGG: ton:TON_0876 DOMON; PFAM: DOMON domain protein; SMART: DOMON domain protein; SPTR: DOMON; PFAM: DOMON domain; DOMON domain-containing protein complement(225069..225572) Spirochaeta smaragdinae DSM 11293 9488298 YP_003801973.1 CDS Spirs_0222 NC_014364.1 225742 228162 R COGs: COG1882 pyruvate-formate lyase; InterPro IPR010098:IPR004184:IPR001150; KEGG: str:Sterm_1074 pyruvate formate-lyase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: formate C-acetyltransferase; SPTR: uncharacterized protein; TIGRFAM: pyruvate formate-lyase; PFAM: glycine radical; pyruvate formate lyase; TIGRFAM: pyruvate formate-lyase; pyruvate formate-lyase complement(225742..228162) Spirochaeta smaragdinae DSM 11293 9488299 YP_003801974.1 CDS Spirs_0223 NC_014364.1 228238 229017 R COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: cbt:CLH_0701 deoxyribose operon repressor; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator complement(228238..229017) Spirochaeta smaragdinae DSM 11293 9488300 YP_003801975.1 CDS Spirs_0224 NC_014364.1 229146 229820 D COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: hor:Hore_18470 L-fuculose phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: L-fuculose phosphate aldolase; PFAM: class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; class II aldolase/adducin family protein 229146..229820 Spirochaeta smaragdinae DSM 11293 9488301 YP_003801976.1 CDS Spirs_0225 NC_014364.1 229964 230998 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: gka:GK2115 transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 229964..230998 Spirochaeta smaragdinae DSM 11293 9488302 YP_003801977.1 CDS Spirs_0226 NC_014364.1 231015 231932 D COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterProIPR012839:IPR007197:IPR001450:IPR017896:IPR 011352:IPR017900:IPR005829:IPR001989; KEGG: rpc:RPC_1176 glycyl-radical activating protein; PFAM: radical SAM protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: [formate-C-acetyltransferase]-activating enzyme; SPTR: glycyl-radical enzyme activating; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: radical SAM superfamily; TIGRFAM: glycyl-radical enzyme activating protein family; glycyl-radical enzyme activating protein family 231015..231932 Spirochaeta smaragdinae DSM 11293 9488303 YP_003801978.1 CDS Spirs_0227 NC_014364.1 231932 232858 D KEGG: pca:Pcar_0934 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 231932..232858 Spirochaeta smaragdinae DSM 11293 9488304 YP_003801979.1 CDS Spirs_0228 NC_014364.1 232869 233420 D KEGG: dps:DP0584 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 232869..233420 Spirochaeta smaragdinae DSM 11293 9488305 YP_003801980.1 CDS Spirs_0229 NC_014364.1 233632 234588 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: monosacharide ABC transporter periplasmic monosacharide-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ABC transporter periplasmic sugar binding protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 233632..234588 Spirochaeta smaragdinae DSM 11293 9488306 YP_003801981.1 CDS Spirs_0230 NC_014364.1 234682 235380 D COGs: COG5618 periplasmic lipoprotein; InterPro IPR014582; KEGG: acr:Acry_1065 periplasmic lipoprotein-like protein; PFAM: periplasmic lipoprotein; SPTR: Periplasmic lipoprotein-like protein; PFAM: Predicted periplasmic lipoprotein (DUF2291); periplasmic lipoprotein 234682..235380 Spirochaeta smaragdinae DSM 11293 9488307 YP_003801982.1 CDS Spirs_0231 NC_014364.1 235382 236935 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: mlo:mll7012 ribose ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 235382..236935 Spirochaeta smaragdinae DSM 11293 9488308 YP_003801983.1 CDS Spirs_0232 NC_014364.1 236913 238043 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: sme:SM_b20352 sugar ABC transporter permease; PFAM: inner-membrane translocator; SPTR: ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 236913..238043 Spirochaeta smaragdinae DSM 11293 9488309 YP_003801984.1 CDS Spirs_0233 NC_014364.1 238088 239269 R COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: cce:Ccel_1965 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II; class I and II aminotransferase complement(238088..239269) Spirochaeta smaragdinae DSM 11293 9488310 YP_003801985.1 CDS Spirs_0234 NC_014364.1 239390 240028 D COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: aoe:Clos_1744 YheO domain-containing protein; PFAM: YheO domain protein; SPTR: uncharacterized protein; manually curated; PFAM: YheO-like PAS domain; YheO domain-containing protein 239390..240028 Spirochaeta smaragdinae DSM 11293 9488311 YP_003801986.1 CDS Spirs_0235 NC_014364.1 240080 240751 R COGs: COG2964 conserved hypothetical protein; InterPro IPR013559; KEGG: dvl:Dvul_1030 YheO domain-containing protein; PFAM: YheO domain protein; SPTR: uncharacterized protein; PFAM: YheO-like PAS domain; YheO domain-containing protein complement(240080..240751) Spirochaeta smaragdinae DSM 11293 9488312 YP_003801987.1 CDS Spirs_0236 NC_014364.1 241034 242455 D COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: cdl:CDR20291_2109 sodium/solute symporter; PFAM: Na+/solute symporter; SPTR: Na+/solute symporter; PFAM: Sodium:solute symporter family; Na+/solute symporter 241034..242455 Spirochaeta smaragdinae DSM 11293 9488313 YP_003801988.1 CDS Spirs_0237 NC_014364.1 242546 244480 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR006076; KEGG: str:Sterm_3522 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Predicted protein; PFAM: domain; FAD binding domain; FAD dependent oxidoreductase 242546..244480 Spirochaeta smaragdinae DSM 11293 9488314 YP_003801989.1 CDS Spirs_0238 NC_014364.1 244485 244781 D InterPro IPR001450:IPR017896:IPR017900; KEGG: ckr:CKR_2705 hypothetical protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: Predicted protein; PFAM: 4Fe-4S binding domain; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 244485..244781 Spirochaeta smaragdinae DSM 11293 9488315 YP_003801990.1 CDS Spirs_0239 NC_014364.1 244878 245948 D COGs: COG0142 geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: geranylgeranyl pyrophosphate synthase; PFAM: polyprenyl synthetase; SPTR: geranylgeranyl pyrophosphate synthase; PFAM: polyprenyl synthetase; polyprenyl synthetase 244878..245948 Spirochaeta smaragdinae DSM 11293 9488316 YP_003801991.1 CDS Spirs_0240 NC_014364.1 245963 247480 R COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: eat:EAT1b_0890 peptidase M23; PFAM: peptidase M23; SPTR: peptidase M23; PFAM: peptidase family M23; peptidase M23 complement(245963..247480) Spirochaeta smaragdinae DSM 11293 9488317 YP_003801992.1 CDS Spirs_0241 NC_014364.1 247587 248948 D COGs: COG0415 deoxyribodipyrimidine photolyase; InterPro IPR006050:IPR005101:IPR008148; KEGG: hmo:HM1_1861 deoxyribodipyrimidine photolyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; SPTR: deoxyribodipyrimidine photolyase; manually curated; PFAM: FAD binding domain of DNA photolyase; DNA photolyase; TIGRFAM: photolyase PhrII; DNA photolyase FAD-binding protein 247587..248948 Spirochaeta smaragdinae DSM 11293 9488318 YP_003801993.1 CDS Spirs_0242 NC_014364.1 249013 249726 D COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: sfu:Sfum_0938 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: fumarylacetoacetate (FAA) hydrolase; PRIAM: Ureidoglycolate lyase; SPTR: 5-carboxymethyl-2-hydroxymuconate delta-isomerase; PFAM: Fumarylacetoacetate (FAA) hydrolase family; ureidoglycolate lyase 249013..249726 Spirochaeta smaragdinae DSM 11293 9488319 YP_003801994.1 CDS Spirs_0243 NC_014364.1 249848 250885 D COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667; KEGG: gem:GM21_1931 phosphoesterase RecJ domain protein; PFAM: phosphoesterase RecJ domain protein; SPTR: phosphoesterase RecJ domain protein; PFAM: DHH family; phosphoesterase RecJ 249848..250885 Spirochaeta smaragdinae DSM 11293 9488320 YP_003801995.1 CDS Spirs_0244 NC_014364.1 250896 251363 R InterPro IPR008254; KEGG: mac:MA2078 flavodoxin; SPTR: Flavodoxin; hypothetical protein complement(250896..251363) Spirochaeta smaragdinae DSM 11293 9488321 YP_003801996.1 CDS Spirs_0246 NC_014364.1 251906 252343 R KEGG: fnu:FN1201 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(251906..252343) Spirochaeta smaragdinae DSM 11293 9488323 YP_003801997.1 CDS Spirs_0247 NC_014364.1 252373 253653 R COGs: COG1906 conserved hypothetical protein; InterPro IPR007294; KEGG: dol:Dole_1082 hypothetical protein; PFAM: protein of unknown function DUF401; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF401); TIGRFAM: converved hypothetical integral membrane protein; hypothetical protein complement(252373..253653) Spirochaeta smaragdinae DSM 11293 9488324 YP_003801998.1 CDS Spirs_0248 NC_014364.1 253778 254299 D COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tye:THEYE_A1865 ferric uptake regulation protein; PFAM: ferric-uptake regulator; SPTR: ferric uptake regulation protein; PFAM: ferric uptake regulator family; Fur family ferric uptake regulator 253778..254299 Spirochaeta smaragdinae DSM 11293 9488325 YP_003801999.1 CDS Spirs_0249 NC_014364.1 254379 254678 D KEGG: tit:Thit_1682 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 254379..254678 Spirochaeta smaragdinae DSM 11293 9488326 YP_003802000.1 CDS Spirs_0250 NC_014364.1 254675 255043 D COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: mla:Mlab_1056 hypothetical protein; PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: dinitrogenase iron-molybdenum cofactor; dinitrogenase iron-molybdenum cofactor biosynthesis protein 254675..255043 Spirochaeta smaragdinae DSM 11293 9488327 YP_003802001.1 CDS Spirs_0251 NC_014364.1 255047 255403 D COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: mma:MM_0988 hypothetical protein; PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: Conserved protein; PFAM: dinitrogenase iron-molybdenum cofactor; dinitrogenase iron-molybdenum cofactor biosynthesis protein 255047..255403 Spirochaeta smaragdinae DSM 11293 9488328 YP_003802002.1 CDS Spirs_0252 NC_014364.1 255400 256272 D COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR002586:IPR001450:IPR017896:IPR017900; KEGG: pth:PTH_0584 MinD family ATPase; PFAM: cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; 4Fe-4S binding domain; cobyrinic acid ac-diamide synthase 255400..256272 Spirochaeta smaragdinae DSM 11293 9488329 YP_003802003.1 CDS Spirs_0253 NC_014364.1 256269 257195 D COGs: COG1149 MinD superfamily P-loop ATPase containing an inserted ferredoxin domain; InterPro IPR002586:IPR001450:IPR017896:IPR017900; KEGG: mta:Moth_1408 cobyrinic acid a,c-diamide synthase; PFAM: cobyrinic acid ac-diamide synthase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: cobyrinic acid a,c-diamide synthase; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase 256269..257195 Spirochaeta smaragdinae DSM 11293 9488330 YP_003802004.1 CDS Spirs_0254 NC_014364.1 257236 258060 D COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR019591; KEGG: ddf:DEFDS_1268 ATP-binding protein, CobQ/CobB/MinD/ParA family; PFAM: ATPase-like, ParA/MinD; SPTR: nucleotide-binding protein; PFAM: ParA/MinD ATPase like; Anion-transporting ATPase; ATPase-like, ParA/MinD 257236..258060 Spirochaeta smaragdinae DSM 11293 9488331 YP_003802005.1 CDS Spirs_0255 NC_014364.1 258190 260424 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dba:Dbac_1917 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 258190..260424 Spirochaeta smaragdinae DSM 11293 9488332 YP_003802006.1 CDS Spirs_0256 NC_014364.1 260436 260930 D COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: cce:Ccel_2314 chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: chemotaxis protein CheW; PFAM: CheW-like domain; chemotaxis protein CheW 260436..260930 Spirochaeta smaragdinae DSM 11293 9488333 YP_003802007.1 CDS Spirs_0257 NC_014364.1 261105 261710 D COGs: COG0170 Dolichol kinase; InterPro IPR000374; KEGG: tde:TDE2717 phosphatidate cytidylyltransferase, PFAM: phosphatidate cytidylyltransferase; SPTR: phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; phosphatidate cytidylyltransferase 261105..261710 Spirochaeta smaragdinae DSM 11293 9488334 YP_003802008.1 CDS Spirs_0258 NC_014364.1 261720 262487 R KEGG: tde:TDE1445 hypothetical protein; SPTR: lipoprotein; hypothetical protein complement(261720..262487) Spirochaeta smaragdinae DSM 11293 9488335 YP_003802009.1 CDS Spirs_0259 NC_014364.1 262520 264109 R InterPro IPR005199; KEGG: mmw:Mmwyl1_1639 hypothetical protein; PFAM: glycoside hydrolase family 79; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase family 79, N-terminal domain; glycoside hydrolase family protein complement(262520..264109) Spirochaeta smaragdinae DSM 11293 9488336 YP_003802010.1 CDS Spirs_0260 NC_014364.1 264202 264897 D COGs: COG5497 secreted protein; InterPro IPR018725; KEGG: tde:TDE1519 hypothetical protein; PFAM: protein of unknown function DUF2259, secreted; SPTR: uncharacterized protein; PFAM: Predicted secreted protein (DUF2259); hypothetical protein 264202..264897 Spirochaeta smaragdinae DSM 11293 9488337 YP_003802011.1 CDS Spirs_0261 NC_014364.1 265017 266447 D COGs: COG0442 prolyl-tRNA synthetase; InterProIPR002316:IPR004499:IPR002314:IPR004154:IPR 016061:IPR006195; KEGG: paa:Paes_1587 prolyl-tRNA synthetase; PFAM: anticodon-binding domain protein; tRNA synthetase class II (G H P and S); prolyl-tRNA synthetase, class II-like; PRIAM: Proline--tRNA ligase; SPTR: prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; PFAM: anticodon binding domain; prolyl-tRNA synthetase, C-terminal; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family I; prolyl-tRNA synthetase 265017..266447 Spirochaeta smaragdinae DSM 11293 9488338 YP_003802012.1 CDS Spirs_0262 NC_014364.1 266484 267131 D KEGG: saz:Sama_1067 sulfate transporter YchM; SPTR: sulfate permease family protein; hypothetical protein 266484..267131 Spirochaeta smaragdinae DSM 11293 9488339 YP_003802013.1 CDS Spirs_0263 NC_014364.1 267156 268391 R COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: tde:TDE1111 transporter SPTR: transporter; PFAM: Sodium:dicarboxylate symporter family; transporter complement(267156..268391) Spirochaeta smaragdinae DSM 11293 9488340 YP_003802014.1 CDS Spirs_0264 NC_014364.1 268436 269101 R KEGG: cpi:Cpin_6701 short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase; hypothetical protein complement(268436..269101) Spirochaeta smaragdinae DSM 11293 9488341 YP_003802015.1 CDS Spirs_0265 NC_014364.1 269233 270891 D COGs: COG0171 NAD synthase; InterPro IPR003694:IPR003010:IPR014445; KEGG: aca:ACP_0671 NAD+ synthetase; PFAM: NAD synthase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: NAD+ synthetase; TIGRFAM: NAD+ synthetase; PFAM: NAD synthase; carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase; NAD+ synthetase 269233..270891 Spirochaeta smaragdinae DSM 11293 9488342 YP_003802016.1 CDS Spirs_0266 NC_014364.1 270879 274286 R COGs: COG0366 glycosidase; InterPro IPR006589:IPR006047; KEGG: aba:acid345_1492 alpha amylase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase; PFAM: alpha amylase, catalytic domain; alpha amylase catalytic subunit complement(270879..274286) Spirochaeta smaragdinae DSM 11293 9488343 YP_003802017.1 CDS Spirs_0267 NC_014364.1 274312 274893 R COGs: COG1259 conserved hypothetical protein; InterPro IPR003729:IPR001943; KEGG: srm:SRM_02353 uncharacterized ACR; PFAM: protein of unknown function DUF151; UvrB/UvrC protein; SPTR: Uncharacterized ACR, COG1259 family; PFAM: Uncharacterised ACR, COG1259; UvrB/uvrC motif; hypothetical protein complement(274312..274893) Spirochaeta smaragdinae DSM 11293 9488344 YP_003802018.1 CDS Spirs_0268 NC_014364.1 274964 275503 R COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034:IPR020827; KEGG: bba:Bd3633 asparaginase; PFAM: asparaginase/glutaminase; SPTR: uncharacterized protein; PFAM: asparaginase; asparaginase/glutaminase complement(274964..275503) Spirochaeta smaragdinae DSM 11293 9488345 YP_003802019.1 CDS Spirs_0269 NC_014364.1 275505 276575 R COGs: COG3426 Butyrate kinase; InterPro IPR000890:IPR011245; KEGG: amt:Amet_4308 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: Butyrate kinase; TIGRFAM: butyrate kinase; PFAM: acetokinase family; TIGRFAM: butyrate kinase; butyrate kinase complement(275505..276575) Spirochaeta smaragdinae DSM 11293 9488346 YP_003802020.1 CDS Spirs_0270 NC_014364.1 276644 277225 R COGs: COG0193 peptidyl-tRNA hydrolase; InterPro IPR001328:IPR018171; KEGG: scl:sce6936 hypothetical protein; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase complement(276644..277225) Spirochaeta smaragdinae DSM 11293 9488347 YP_003802021.1 CDS Spirs_0271 NC_014364.1 277266 278453 D COGs: COG1075 acetyltransferase and hydrolase with the alpha/beta hydrolase fold; InterPro IPR012908; KEGG: cno:NT01CX_0630 lipase; PFAM: PGAP1 family protein; PRIAM: Triacylglycerol lipase; SPTR: Lipase; PFAM: PGAP1-like protein; triacylglycerol lipase 277266..278453 Spirochaeta smaragdinae DSM 11293 9488348 YP_003802022.1 CDS Spirs_0272 NC_014364.1 278450 279064 R COGs: COG1739 conserved hypothetical protein; InterPro IPR015796:IPR001498:IPR020569; KEGG: tde:TDE1321 hypothetical protein; PFAM: protein of unknown function UPF0029; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0029; TIGRFAM: conserved hypothetical protein TIGR00257; hypothetical protein complement(278450..279064) Spirochaeta smaragdinae DSM 11293 9488349 YP_003802023.1 CDS Spirs_0273 NC_014364.1 279057 280016 R COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471:IPR001395; KEGG: kcr:Kcr_0281 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(279057..280016) Spirochaeta smaragdinae DSM 11293 9488350 YP_003802024.1 CDS Spirs_0274 NC_014364.1 280222 280914 D InterPro IPR008258; KEGG: lhk:LHK_00755 Slt; PFAM: lytic transglycosylase catalytic; SPTR: Slt; PFAM: transglycosylase SLT domain; lytic transglycosylase 280222..280914 Spirochaeta smaragdinae DSM 11293 9488351 YP_003802025.1 CDS Spirs_0275 NC_014364.1 280924 282813 D COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006268:IPR006218:IPR001086:IPR002912; KEGG: sfu:Sfum_3724 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; prephenate dehydratase; amino acid-binding ACT domain protein; PRIAM: 3-deoxy-7-phosphoheptulonate synthase., prephenate dehydratase; SPTR: prephenate dehydratase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: prephenate dehydratase; ACT domain; DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; phospho-2-dehydro-3-deoxyheptonate aldolase 280924..282813 Spirochaeta smaragdinae DSM 11293 9488352 YP_003802026.1 CDS Spirs_0276 NC_014364.1 282818 284236 R KEGG: tde:TDE2048 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(282818..284236) Spirochaeta smaragdinae DSM 11293 9488353 YP_003802027.1 CDS Spirs_0277 NC_014364.1 284295 284837 D KEGG: dba:Dbac_2899 GTP-binding protein; SPTR: GTP-binding protein; GTP-binding protein 284295..284837 Spirochaeta smaragdinae DSM 11293 9488354 YP_003802028.1 CDS Spirs_0278 NC_014364.1 284883 285662 D KEGG: ele:Elen_1101 major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; hypothetical protein 284883..285662 Spirochaeta smaragdinae DSM 11293 9488355 YP_003802029.1 CDS Spirs_0279 NC_014364.1 285797 287329 R COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR013027:IPR003953; KEGG: shi:Shel_26410 succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: succinate dehydrogenase/fumarate reductase flavoprotein subunit; PFAM: FAD binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein complement(285797..287329) Spirochaeta smaragdinae DSM 11293 9488356 YP_003802030.1 CDS Spirs_0280 NC_014364.1 287552 288463 D COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119:IPR003006; KEGG: dhd:Dhaf_1104 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator 287552..288463 Spirochaeta smaragdinae DSM 11293 9488357 YP_003802031.1 CDS Spirs_0281 NC_014364.1 288534 290120 D COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR000014:IPR001054; KEGG: scl:sce7616 adenylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; PAS domain containing protein; SPTR: adenylate cyclase; TIGRFAM: PAS sensor protein; PFAM: adenylate and Guanylate cyclase catalytic domain; TIGRFAM: PAS domain S-box; adenylate/guanylate cyclase 288534..290120 Spirochaeta smaragdinae DSM 11293 9488358 YP_003802032.1 CDS Spirs_0282 NC_014364.1 290131 292629 D COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155; KEGG: ter:Tery_1841 peptidase C14, caspase catalytic subunit P20; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: peptidase C14, caspase catalytic subunit p20; PBS lyase HEAT domain-containing protein repeat-containing protein 290131..292629 Spirochaeta smaragdinae DSM 11293 9488359 YP_003802033.1 CDS Spirs_0283 NC_014364.1 292677 295097 R COGs: COG0495 leucyl-tRNA synthetase; InterPro IPR002302:IPR002300:IPR013155:IPR001412; KEGG: gwc:GWCH70_2764 leucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: Leucine--tRNA ligase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family; leucyl-tRNA synthetase complement(292677..295097) Spirochaeta smaragdinae DSM 11293 9488360 YP_003802034.1 CDS Spirs_0284 NC_014364.1 295144 296406 R COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: bbz:BbuZS7_0204 hemolysin; PFAM: protein of unknown function DUF21; CBS domain containing protein; transporter-associated region; SMART: CBS domain containing protein; SPTR: Hemolysin, ; PFAM: CBS domain; Domain of unknown function DUF21; transporter associated domain; hypothetical protein complement(295144..296406) Spirochaeta smaragdinae DSM 11293 9488361 YP_003802035.1 CDS Spirs_0285 NC_014364.1 296529 298400 D COGs: COG0326 Molecular chaperone HSP90 family; InterProIPR020575:IPR003594:IPR020576:IPR001404:IPR 019805; KEGG: tde:TDE2480 heat shock protein 90; PFAM: heat shock protein Hsp90-like; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Chaperone protein HtpG; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein; heat shock protein Hsp90 296529..298400 Spirochaeta smaragdinae DSM 11293 9488362 YP_003802036.1 CDS Spirs_0286 NC_014364.1 298420 298812 D COGs: COG5341 conserved hypothetical protein; InterPro IPR010739; KEGG: tpp:TPASS_1032 hypothetical protein; PFAM: protein of unknown function DUF1312; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1312); hypothetical protein 298420..298812 Spirochaeta smaragdinae DSM 11293 9488363 YP_003802037.1 CDS Spirs_0287 NC_014364.1 298829 299461 D KEGG: ade:Adeh_2194 cytochrome C assembly protein; SPTR: cytochrome C assembly protein; PFAM: ResB-like family; hypothetical protein 298829..299461 Spirochaeta smaragdinae DSM 11293 9488364 YP_003802038.1 CDS Spirs_0288 NC_014364.1 299458 300246 D COGs: COG0755 ABC-type transporter involved in cytochrome C biogenesis permease; InterPro IPR002541; KEGG: gsu:GSU3283 CcmF/CcyK/CcsA family cytochrome C biogenesis protein; PFAM: cytochrome C assembly protein; SPTR: cytochrome C biogenesis protein, CcmF/CcyK/CcsA family; PFAM: cytochrome C assembly protein; TIGRFAM: cytochrome C biogenesis protein CcsB; cytochrome C assembly protein 299458..300246 Spirochaeta smaragdinae DSM 11293 9488365 YP_003802039.1 CDS Spirs_0289 NC_014364.1 300297 300707 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: gur:Gura_3391 two component, sigma-54 specific, fis family transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; response regulator receiver protein 300297..300707 Spirochaeta smaragdinae DSM 11293 9488366 YP_003802040.1 CDS Spirs_0290 NC_014364.1 300712 301980 D COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932:IPR010822:IPR001789; KEGG: rru:Rru_A0553 response regulator receiver signal transduction histidine kinase; PFAM: stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: Sensor protein; PFAM: stage II sporulation protein E (SpoIIE); response regulator receiver modulated serine phosphatase 300712..301980 Spirochaeta smaragdinae DSM 11293 9488367 YP_003802041.1 CDS Spirs_0291 NC_014364.1 301967 302473 D InterPro IPR002645; KEGG: nhl:Nhal_3172 sulfate transporter/antisigma-factor antagonist STAS; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: sulfate transporter/antisigma-factor antagonist STAS; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 301967..302473 Spirochaeta smaragdinae DSM 11293 9488368 YP_003802042.1 CDS Spirs_0292 NC_014364.1 302620 303213 D COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: gvi:glr4157 hypothetical protein; PFAM: transcriptional regulator PadR family protein; SPTR: Glr4157 protein; PFAM: transcriptional regulator PadR-like family; virulence activator alpha C-term; PadR family transcriptional regulator 302620..303213 Spirochaeta smaragdinae DSM 11293 9488369 YP_003802043.1 CDS Spirs_0293 NC_014364.1 303210 304667 D KEGG: mbn:Mboo_2182 NAD(P)H dehydrogenase (quinone); SPTR: NAD(P)H dehydrogenase (Quinone); PFAM: NADPH-dependent FMN reductase; NAD(P)H dehydrogenase (quinone) 303210..304667 Spirochaeta smaragdinae DSM 11293 9488370 YP_003802044.1 CDS Spirs_0294 NC_014364.1 304717 305328 R COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR010089:IPR008254; KEGG: geo:Geob_3294 TrpR binding protein WrbA; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavoprotein wrbA; TIGRFAM: flavoprotein WrbA; PFAM: NADPH-dependent FMN reductase; TIGRFAM: NAD(P)H:quinone oxidoreductase, type IV; flavoprotein WrbA complement(304717..305328) Spirochaeta smaragdinae DSM 11293 9488371 YP_003802045.1 CDS Spirs_0295 NC_014364.1 305325 305783 R InterPro IPR000835; KEGG: lbf:LBF_0068 transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: HTH-type MarR family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator complement(305325..305783) Spirochaeta smaragdinae DSM 11293 9488372 YP_003802046.1 CDS Spirs_0296 NC_014364.1 306038 306748 R KEGG: mxa:MXAN_3470 lipoprotein; SPTR: lipoprotein; PFAM: NlpC/P60 family; lipoprotein complement(306038..306748) Spirochaeta smaragdinae DSM 11293 9488373 YP_003802047.1 CDS Spirs_0297 NC_014364.1 306741 307352 R COGs: COG0293 23S rRNA methylase; InterPro IPR002877:IPR016448; KEGG: tde:TDE1968 cell division protein FtsJ; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: ribosomal RNA large subunit methyltransferase E; manually curated; PFAM: FtsJ-like methyltransferase; TIGRFAM: cell division protein FtsJ; ribosomal RNA methyltransferase RrmJ/FtsJ complement(306741..307352) Spirochaeta smaragdinae DSM 11293 9488374 YP_003802048.1 CDS Spirs_0298 NC_014364.1 307502 308146 D COGs: COG0705 membrane protein; InterPro IPR002610; KEGG: tde:TDE0124 rhomboid family protein; PFAM: rhomboid family protein; SPTR: rhomboid family protein; PFAM: Rhomboid family; rhomboid family protein 307502..308146 Spirochaeta smaragdinae DSM 11293 9488375 YP_003802049.1 CDS Spirs_0299 NC_014364.1 308143 308889 D KEGG: tde:TDE0123 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 308143..308889 Spirochaeta smaragdinae DSM 11293 9488376 YP_003802050.1 CDS Spirs_0300 NC_014364.1 308904 310010 R COGs: COG1816 adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: cts:Ctha_0358 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: adenosine deaminase; SPTR: adenosine deaminase; TIGRFAM: adenosine deaminase; manually curated; PFAM: adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; adenosine deaminase complement(308904..310010) Spirochaeta smaragdinae DSM 11293 9488377 YP_003802051.1 CDS Spirs_0301 NC_014364.1 310099 311700 D COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR006158:IPR007197:IPR000385; KEGG: pca:Pcar_2487 Fe-S oxidoreductase; PFAM: radical SAM protein; cobalamin B12-binding domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: radical SAM superfamily; B12 binding domain; radical SAM protein 310099..311700 Spirochaeta smaragdinae DSM 11293 9488378 YP_003802052.1 CDS Spirs_0302 NC_014364.1 311691 313166 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485:IPR001589; KEGG: ate:Athe_1997 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(311691..313166) Spirochaeta smaragdinae DSM 11293 9488379 YP_003802053.1 CDS Spirs_0303 NC_014364.1 313177 313878 R COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: hsm:HSM_1240 L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; SPTR: L-ribulose-5-phosphate 4-epimerase; PFAM: class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; class II aldolase/adducin family protein complement(313177..313878) Spirochaeta smaragdinae DSM 11293 9488380 YP_003802054.1 CDS Spirs_0304 NC_014364.1 313871 314740 R COGs: COG3623 L-xylulose-5-phosphate 3-epimerase; InterPro IPR004560:IPR012307; KEGG: spe:Spro_3938 L-xylulose 5-phosphate 3-epimerase; PFAM: Xylose isomerase domain protein TIM barrel; PRIAM: L-ribulose-5-phosphate 3-epimerase; SPTR: uncharacterized protein; TIGRFAM: hexulose-6-phosphate isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: hexulose-6-phosphate isomerase; hexulose-6-phosphate isomerase complement(313871..314740) Spirochaeta smaragdinae DSM 11293 9488381 YP_003802055.1 CDS Spirs_0305 NC_014364.1 314737 315393 R COGs: COG0269 3-hexulose-6-phosphate synthase and related protein; InterPro IPR001754; KEGG: spe:Spro_3937 3-keto-L-gulonate-6-phosphate decarboxylase; PFAM: orotidine 5'-phosphate decarboxylase; SPTR: 3-keto-L-gulonate-6-phosphate decarboxylase ulaD; PFAM: orotidine 5'-phosphate decarboxylase / HUMPS family; orotidine 5'-phosphate decarboxylase complement(314737..315393) Spirochaeta smaragdinae DSM 11293 9488382 YP_003802056.1 CDS Spirs_0306 NC_014364.1 315666 316730 D COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; KEGG: str:Sterm_0141 L-ascorbate 6-phosphate lactonase; SPTR: L-ascorbate 6-phosphate lactonase; L-ascorbate 6-phosphate lactonase 315666..316730 Spirochaeta smaragdinae DSM 11293 9488383 YP_003802057.1 CDS Spirs_0307 NC_014364.1 316826 318184 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: tpp:TPASS_0074 sugar ABC transporter periplasmic binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter periplasmic binding protein (Y4oP); PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 316826..318184 Spirochaeta smaragdinae DSM 11293 9488384 YP_003802058.1 CDS Spirs_0308 NC_014364.1 318256 319140 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tpp:TPASS_0075 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease (Y4oQ); PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 318256..319140 Spirochaeta smaragdinae DSM 11293 9488385 YP_003802059.1 CDS Spirs_0309 NC_014364.1 319155 319988 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tpp:TPASS_0076 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 319155..319988 Spirochaeta smaragdinae DSM 11293 9488386 YP_003802060.1 CDS Spirs_0310 NC_014364.1 320000 321142 D COGs: COG0407 uroporphyrinogen-III decarboxylase; InterPro IPR018039; KEGG: dsy:DSY4756 hypothetical protein; SPTR: uncharacterized protein; PFAM: uroporphyrinogen decarboxylase (URO-D); hypothetical protein 320000..321142 Spirochaeta smaragdinae DSM 11293 9488387 YP_003802061.1 CDS Spirs_0311 NC_014364.1 321241 322020 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: pca:Pcar_0940 DeoR-type transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 321241..322020 Spirochaeta smaragdinae DSM 11293 9488388 YP_003802062.1 CDS Spirs_0312 NC_014364.1 322127 323911 R COGs: COG0173 aspartyl-tRNA synthetase; InterProIPR002312:IPR004365:IPR004364:IPR004115:IPR 006195:IPR004524; KEGG: tde:TDE1587 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; GAD domain protein; SPTR: aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type; aspartyl-tRNA synthetase complement(322127..323911) Spirochaeta smaragdinae DSM 11293 9488389 YP_003802063.1 CDS Spirs_0313 NC_014364.1 323929 324651 D COGs: COG2949 Uncharacterized membrane protein; InterPro IPR003848; KEGG: asa:ASA_3722 SanA protein; PFAM: protein of unknown function DUF218; SPTR: SanA protein; PFAM: DUF218 domain; hypothetical protein 323929..324651 Spirochaeta smaragdinae DSM 11293 9488390 YP_003802064.1 CDS Spirs_0314 NC_014364.1 324710 325132 R KEGG: tde:TDE0199 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(324710..325132) Spirochaeta smaragdinae DSM 11293 9488391 YP_003802065.1 CDS Spirs_0315 NC_014364.1 325215 325895 D COGs: COG0313 methyltransferase; InterPro IPR000878:IPR018063:IPR008189; KEGG: tde:TDE0200 tetrapyrrole methylase family protein; PFAM: uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; SPTR: Tetrapyrrole methylase family protein; PFAM: Tetrapyrrole (Corrin/Porphyrin) methylases; TIGRFAM: conserved hypothetical protein TIGR00096; uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase 325215..325895 Spirochaeta smaragdinae DSM 11293 9488392 YP_003802066.1 CDS Spirs_0316 NC_014364.1 325944 326231 D InterPro IPR007412; KEGG: tde:TDE0201 hypothetical protein; PFAM: anti-sigma-28 factor FlgM family protein; SPTR: uncharacterized protein; PFAM: anti-sigma-28 factor, FlgM; anti-sigma-28 factor FlgM family protein 325944..326231 Spirochaeta smaragdinae DSM 11293 9488393 YP_003802067.1 CDS Spirs_0317 NC_014364.1 326353 327498 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: tde:TDE0051 alcohol dehydrogenase, iron-containing; PFAM: iron-containing alcohol dehydrogenase; SPTR: alcohol dehydrogenase, iron-containing; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 326353..327498 Spirochaeta smaragdinae DSM 11293 9488394 YP_003802068.1 CDS Spirs_0318 NC_014364.1 327508 328377 D COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: tde:TDE0050 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RNA methyltransferase, TrmH family; PFAM: SpoU rRNA methylase family; tRNA/rRNA methyltransferase SpoU 327508..328377 Spirochaeta smaragdinae DSM 11293 9488395 YP_003802069.1 CDS Spirs_0319 NC_014364.1 328340 328570 R COGs: COG0695 glutaredoxin and related protein; InterPro IPR002109:IPR011911; KEGG: dtu:Dtur_0034 glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin; SPTR: glutaredoxin-like protein, YruB-family; TIGRFAM: glutaredoxin-like protein, YruB-family; PFAM: glutaredoxin; TIGRFAM: glutaredoxin-like protein, YruB-family; glutaredoxin-like protein, YruB-family complement(328340..328570) Spirochaeta smaragdinae DSM 11293 9488396 YP_003802070.1 CDS Spirs_0320 NC_014364.1 328769 330250 R COGs: COG1639 signal transduction protein; InterPro IPR003607:IPR013976:IPR006675; KEGG: tde:TDE2279 HD domain-containing protein; PFAM: metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase complement(328769..330250) Spirochaeta smaragdinae DSM 11293 9488397 YP_003802071.1 CDS Spirs_0321 NC_014364.1 330325 332715 R COGs: COG1067 ATP-dependent protease; InterPro IPR001984; KEGG: dsa:Desal_2757 peptidase S16; SPTR: peptidase S16; PFAM: Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related ATP-dependent protease; peptidase S16 complement(330325..332715) Spirochaeta smaragdinae DSM 11293 9488398 YP_003802072.1 CDS Spirs_0322 NC_014364.1 332792 333553 D COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: tde:TDE2208 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: conserved hypothetical protein TIGR00486; hypothetical protein 332792..333553 Spirochaeta smaragdinae DSM 11293 9488399 YP_003802073.1 CDS Spirs_0323 NC_014364.1 333553 334050 D COGs: COG0597 Lipoprotein signal peptidase; InterPro IPR001872; KEGG: tde:TDE2615 signal peptidase II; PFAM: peptidase A8 signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: lipoprotein signal peptidase; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase; lipoprotein signal peptidase 333553..334050 Spirochaeta smaragdinae DSM 11293 9488400 YP_003802074.1 CDS Spirs_0324 NC_014364.1 334047 334322 D KEGG: oih:OB0617 leader peptide processing enzyme; SPTR: uncharacterized protein; leader peptide processing enzyme 334047..334322 Spirochaeta smaragdinae DSM 11293 9488401 YP_003802075.1 CDS Spirs_0325 NC_014364.1 334332 335972 R KEGG: tde:TDE2751 hypothetical protein; SPTR: uncharacterized protein; manually curated; hypothetical protein complement(334332..335972) Spirochaeta smaragdinae DSM 11293 9488402 YP_003802076.1 CDS Spirs_0326 NC_014364.1 336138 337400 R COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827; KEGG: ade:Adeh_1155 outer membrane protein/protective antigen OMA87-like; PFAM: surface antigen variable number repeat protein; SPTR: Surface antigen variable number repeat domain protein; PFAM: Surface antigen variable number repeat; surface antigen variable number repeat protein complement(336138..337400) Spirochaeta smaragdinae DSM 11293 9488404 YP_003802077.1 CDS Spirs_0327 NC_014364.1 337521 338162 R COGs: COG0450 peroxiredoxin; InterPro IPR000866:IPR019479:IPR017936; KEGG: hor:Hore_12960 alkyl hydroperoxide reductase; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; peroxiredoxin-like; PRIAM: peroxiredoxin; SPTR: Alkyl hydroperoxide reductase; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; peroxiredoxin complement(337521..338162) Spirochaeta smaragdinae DSM 11293 9488405 YP_003802078.1 CDS Spirs_0328 NC_014364.1 338231 338659 R COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: cpb:Cphamn1_0153 ferric uptake regulator, Fur family; PFAM: ferric-uptake regulator; SPTR: ferric uptake regulator, Fur family; PFAM: ferric uptake regulator family; Fur family ferric uptake regulator complement(338231..338659) Spirochaeta smaragdinae DSM 11293 9488406 YP_003802079.1 CDS Spirs_0329 NC_014364.1 338695 339129 R KEGG: cth:Cthe_0226 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(338695..339129) Spirochaeta smaragdinae DSM 11293 9488407 YP_003802080.1 CDS Spirs_0330 NC_014364.1 339211 340458 D COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: mla:Mlab_0811 hypothetical protein; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: phospholipid/glycerol acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase 339211..340458 Spirochaeta smaragdinae DSM 11293 9488408 YP_003802081.1 CDS Spirs_0331 NC_014364.1 340485 341876 D COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR011778; KEGG: azc:AZC_2674 phenylhydantoinase; PFAM: amidohydrolase; SPTR: D-hydantoinase; TIGRFAM: dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; dihydroorotase; dihydropyrimidinase 340485..341876 Spirochaeta smaragdinae DSM 11293 9488409 YP_003802082.1 CDS Spirs_0332 NC_014364.1 341898 342644 D InterPro IPR019734:IPR001440:IPR013026; KEGG: cyc:PCC7424_2005 hypothetical protein; PFAM: TPR repeat-containing protein; SPTR: hypothetical protein; PFAM: Tetratricopeptide repeat; hypothetical protein 341898..342644 Spirochaeta smaragdinae DSM 11293 9488410 YP_003802083.1 CDS Spirs_0333 NC_014364.1 342641 344068 D KEGG: ank:AnaeK_3958 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 342641..344068 Spirochaeta smaragdinae DSM 11293 9488411 YP_003802084.1 CDS Spirs_0334 NC_014364.1 344053 345216 R COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: tde:TDE1500 hypothetical protein; PFAM: capsule synthesis protein, CapA; SPTR: uncharacterized protein; PFAM: Bacterial capsule synthesis protein PGA_cap; capsule synthesis protein, CapA complement(344053..345216) Spirochaeta smaragdinae DSM 11293 9488412 YP_003802085.1 CDS Spirs_0335 NC_014364.1 345309 345497 D KEGG: bid:Bind_2706 FmdB family regulatory protein; SPTR: Regulatory protein, FmdB family; hypothetical protein 345309..345497 Spirochaeta smaragdinae DSM 11293 9488413 YP_003802086.1 CDS Spirs_0336 NC_014364.1 345472 345768 D KEGG: dhd:Dhaf_0280 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 345472..345768 Spirochaeta smaragdinae DSM 11293 9488414 YP_003802087.1 CDS Spirs_0337 NC_014364.1 345772 346572 R COGs: COG1378 transcriptional regulator protein; InterPro IPR002831; KEGG: hor:Hore_06640 transcriptional regulator, TrmB; PFAM: transcriptional regulator TrmB; SPTR: transcriptional regulator, TrmB; PFAM: Sugar-specific transcriptional regulator TrmB; Archaeal transcriptional regulator TrmB; transcriptional regulator, TrmB complement(345772..346572) Spirochaeta smaragdinae DSM 11293 9488415 YP_003802088.1 CDS Spirs_0338 NC_014364.1 346679 347512 R COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200:IPR000150:IPR006379; KEGG: btl:BALH_4896 HAD superfamily hydrolase; PFAM: haloacid dehalogenase type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; Cof-like hydrolase complement(346679..347512) Spirochaeta smaragdinae DSM 11293 9488416 YP_003802089.1 CDS Spirs_0339 NC_014364.1 347576 348814 D InterPro IPR011701; KEGG: cno:NT01CX_1080 major facilitator superfamily protein; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily protein; manually curated; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 347576..348814 Spirochaeta smaragdinae DSM 11293 9488417 YP_003802090.1 CDS Spirs_0340 NC_014364.1 348811 349782 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: pmo:Pmob_0223 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 348811..349782 Spirochaeta smaragdinae DSM 11293 9488418 YP_003802091.1 CDS Spirs_0341 NC_014364.1 349828 350754 R COGs: COG1281 disulfide bond chaperones of the HSP33 family; InterPro IPR000397; KEGG: dat:HRM2_11210 HslO; PFAM: Hsp33 protein; SPTR: HslO; manually curated; PFAM: Hsp33 protein; Hsp33 protein complement(349828..350754) Spirochaeta smaragdinae DSM 11293 9488419 YP_003802092.1 CDS Spirs_0342 NC_014364.1 350839 351366 D COGs: COG0225 peptide methionine sulfoxide reductase; InterPro IPR002569; KEGG: mrb:Mrub_0616 peptide methionine sulfoxide reductase; PFAM: methionine sulfoxide reductase A; PRIAM: peptide-methionine (S)-S-oxide reductase; SPTR: peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; peptide methionine sulfoxide reductase 350839..351366 Spirochaeta smaragdinae DSM 11293 9488420 YP_003802093.1 CDS Spirs_0343 NC_014364.1 351509 352633 D COGs: COG0683 ABC-type branched-chain amino acid transporters periplasmic component; InterPro IPR000709:IPR001828; KEGG: dal:Dalk_4388 extracellular ligand-binding receptor; PFAM: extracellular ligand-binding receptor; SPTR: extracellular ligand-binding receptor; PFAM: Receptor family ligand binding region; extracellular ligand-binding receptor 351509..352633 Spirochaeta smaragdinae DSM 11293 9488421 YP_003802094.1 CDS Spirs_0344 NC_014364.1 352732 353640 D COGs: COG0559 Branched-chain amino acid ABC-type transporter permeases; InterPro IPR001851; KEGG: dat:HRM2_02780 LivH1; PFAM: inner-membrane translocator; SPTR: LivH1; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 352732..353640 Spirochaeta smaragdinae DSM 11293 9488422 YP_003802095.1 CDS Spirs_0345 NC_014364.1 353653 354912 D COGs: COG4177 ABC-type branched-chain amino acid transporter permease; InterPro IPR001851; KEGG: dat:HRM2_02770 LivM1; PFAM: inner-membrane translocator; SPTR: LivM1; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 353653..354912 Spirochaeta smaragdinae DSM 11293 9488423 YP_003802096.1 CDS Spirs_0346 NC_014364.1 354909 355700 D COGs: COG0411 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593:IPR003439:IPR018170; KEGG: dap:Dacet_0895 ABC transporter protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related protein; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter; ABC transporter 354909..355700 Spirochaeta smaragdinae DSM 11293 9488424 YP_003802097.1 CDS Spirs_0347 NC_014364.1 355693 356400 D COGs: COG0410 ABC-type branched-chain amino acid transporters ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: dap:Dacet_0896 ABC transporter protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related protein; PFAM: ABC transporter; ABC transporter 355693..356400 Spirochaeta smaragdinae DSM 11293 9488425 YP_003802098.1 CDS Spirs_0348 NC_014364.1 356426 357070 D COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: cag:Cagg_2623 CBS domain containing protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: CBS domain containing protein; PFAM: CBS domain; signal transduction protein with CBS domains 356426..357070 Spirochaeta smaragdinae DSM 11293 9488426 YP_003802099.1 CDS Spirs_0349 NC_014364.1 357048 359081 R COGs: COG3920 Signal transduction histidine kinase; InterProIPR001638:IPR003594:IPR011495:IPR005467:IPR 000014; KEGG: dsa:Desal_2320 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: extracellular solute-binding protein family 3; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: extracellular solute-binding protein family 3; ATP-binding region ATPase domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: PAS domain S-box; signal transduction histidine kinase complement(357048..359081) Spirochaeta smaragdinae DSM 11293 9488427 YP_003802100.1 CDS Spirs_0350 NC_014364.1 359331 360053 R COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: sbn:Sbal195_0984 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(359331..360053) Spirochaeta smaragdinae DSM 11293 9488428 YP_003802101.1 CDS Spirs_0351 NC_014364.1 360046 360723 R COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: spl:Spea_3398 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane protein complement(360046..360723) Spirochaeta smaragdinae DSM 11293 9488429 YP_003802102.1 CDS Spirs_0352 NC_014364.1 360736 361485 R COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638:IPR018313; KEGG: slo:Shew_3166 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: extracellular solute-binding protein, family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein complement(360736..361485) Spirochaeta smaragdinae DSM 11293 9488430 YP_003802103.1 CDS Spirs_0353 NC_014364.1 361643 362152 D COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: dma:DMR_07850 NAD-reducing hydrogenase subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit 361643..362152 Spirochaeta smaragdinae DSM 11293 9488431 YP_003802104.1 CDS Spirs_0354 NC_014364.1 362139 364037 D COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR011538:IPR019554:IPR019575:IPR001450:IPR 017896:IPR017900:IPR001949; KEGG: dma:DMR_07840 NAD-reducing hydrogenase subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; NADH dehydrogenase (quinone) 362139..364037 Spirochaeta smaragdinae DSM 11293 9488432 YP_003802105.1 CDS Spirs_0355 NC_014364.1 364034 366049 D COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR017896:IPR017900:IPR000283:IPR013352; KEGG: dma:DMR_07830 Fe hydrogenase; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; SPTR: Fe hydrogenase; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: hydrogenases, Fe-only; hydrogenase, Fe-only 364034..366049 Spirochaeta smaragdinae DSM 11293 9488433 YP_003802106.1 CDS Spirs_0356 NC_014364.1 366096 367490 R KEGG: bhy:BHWA1_02074 hypothetical protein; SPTR: uncharacterized protein; metal dependent phosphohydrolase complement(366096..367490) Spirochaeta smaragdinae DSM 11293 9488434 YP_003802107.1 CDS Spirs_0357 NC_014364.1 367569 369443 D KEGG: dan:Dana_GF16459 GF16459 gene product from transcript GF16459-RA; SPTR: uncharacterized protein; hypothetical protein 367569..369443 Spirochaeta smaragdinae DSM 11293 9488435 YP_003802108.1 CDS Spirs_0358 NC_014364.1 369553 370485 R KEGG: dat:HRM2_32580 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(369553..370485) Spirochaeta smaragdinae DSM 11293 9488436 YP_003802109.1 CDS Spirs_0359 NC_014364.1 370478 372568 R COGs: COG3225 ABC-type uncharacterized transporter involved in gliding motility auxiliary component; InterPro IPR019196; KEGG: dat:HRM2_32590 predicted ABC-type transporter, membrane protein; PFAM: ABC-type uncharacterised transporter; SPTR: Predicted ABC-type transport system, membrane protein; PFAM: ABC-type uncharacterized transporter; ABC transporter complement(370478..372568) Spirochaeta smaragdinae DSM 11293 9488437 YP_003802110.1 CDS Spirs_0360 NC_014364.1 372572 373267 R KEGG: dat:HRM2_32600 predicted ABC-type transporter, membrane protein; SPTR: Predicted ABC-type transporter, membrane protein; ABC-type transporter, membrane protein complement(372572..373267) Spirochaeta smaragdinae DSM 11293 9488438 YP_003802111.1 CDS Spirs_0361 NC_014364.1 373260 374195 R COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593:IPR003439; KEGG: dol:Dole_2070 ABC transporter-related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter-related protein; PFAM: ABC transporter; ABC transporter complement(373260..374195) Spirochaeta smaragdinae DSM 11293 9488439 YP_003802112.1 CDS Spirs_0362 NC_014364.1 374324 375214 D COGs: COG1578 conserved hypothetical protein; InterPro IPR002791:IPR014444; KEGG: dol:Dole_1580 hypothetical protein; PFAM: protein of unknown function DUF89; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF89; hypothetical protein 374324..375214 Spirochaeta smaragdinae DSM 11293 9488440 YP_003802113.1 CDS Spirs_0363 NC_014364.1 375253 376419 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: mhu:Mhun_0171 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Probable iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 375253..376419 Spirochaeta smaragdinae DSM 11293 9488441 YP_003802114.1 CDS Spirs_0364 NC_014364.1 376403 377239 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495:IPR005467; KEGG: rci:RCIX1290 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Predicted signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 376403..377239 Spirochaeta smaragdinae DSM 11293 9488442 YP_003802115.1 CDS Spirs_0365 NC_014364.1 377436 378983 D COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439:IPR017871; KEGG: glo:Glov_0246 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 377436..378983 Spirochaeta smaragdinae DSM 11293 9488443 YP_003802116.1 CDS Spirs_0366 NC_014364.1 378980 380527 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004090:IPR013163; KEGG: afw:Anae109_2874 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor complement(378980..380527) Spirochaeta smaragdinae DSM 11293 9488444 YP_003802117.1 CDS Spirs_0367 NC_014364.1 380648 380971 D KEGG: ptm:GSPATT00001744001 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 380648..380971 Spirochaeta smaragdinae DSM 11293 9488445 YP_003802118.1 CDS Spirs_0368 NC_014364.1 380916 381818 R COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495:IPR005467; KEGG: mbn:Mboo_1812 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine Kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase complement(380916..381818) Spirochaeta smaragdinae DSM 11293 9488446 YP_003802119.1 CDS Spirs_0369 NC_014364.1 381815 382933 R COGs: COG2309 leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: cpf:CPF_0868 metalloprotease; PFAM: peptidase M29 aminopeptidase II; SPTR: peptidase M29 aminopeptidase II; PFAM: Thermophilic metalloprotease (M29); peptidase M29 aminopeptidase II complement(381815..382933) Spirochaeta smaragdinae DSM 11293 9488447 YP_003802120.1 CDS Spirs_0370 NC_014364.1 383074 384642 D COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR013656:IPR000014; KEGG: dae:Dtox_1677 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; PRIAM: Diguanylate kinase; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; PAS/PAC sensor-containing diguanylate cyclase 383074..384642 Spirochaeta smaragdinae DSM 11293 9488448 YP_003802121.1 CDS Spirs_0371 NC_014364.1 384879 386042 D COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: hau:Haur_1480 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: transporter major facilitator family; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 384879..386042 Spirochaeta smaragdinae DSM 11293 9488449 YP_003802122.1 CDS Spirs_0372 NC_014364.1 386070 386849 D COGs: COG0708 exonuclease III; InterPro IPR005135:IPR004808:IPR020847:IPR000097; KEGG: str:Sterm_0377 exodeoxyribonuclease III Xth; PFAM: endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: exodeoxyribonuclease III Xth; TIGRFAM: exodeoxyribonuclease III Xth; exodeoxyribonuclease III; PFAM: endonuclease/exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth); exodeoxyribonuclease III Xth 386070..386849 Spirochaeta smaragdinae DSM 11293 9488450 YP_003802123.1 CDS Spirs_0373 NC_014364.1 387259 388287 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: rlg:Rleg_4943 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: uncharacterized protein; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 387259..388287 Spirochaeta smaragdinae DSM 11293 9488451 YP_003802124.1 CDS Spirs_0374 NC_014364.1 388303 389667 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ara:Arad_9887 sugar ABC transporter; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 388303..389667 Spirochaeta smaragdinae DSM 11293 9488452 YP_003802125.1 CDS Spirs_0375 NC_014364.1 389731 390612 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: rec:RHECIAT_PC0000130 probable sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: transporter; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 389731..390612 Spirochaeta smaragdinae DSM 11293 9488453 YP_003802126.1 CDS Spirs_0376 NC_014364.1 390609 391421 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: pmo:Pmob_0307 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: transporter; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 390609..391421 Spirochaeta smaragdinae DSM 11293 9488454 YP_003802127.1 CDS Spirs_0377 NC_014364.1 391422 392099 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: npu:Npun_R2420 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(391422..392099) Spirochaeta smaragdinae DSM 11293 9488455 YP_003802128.1 CDS Spirs_0378 NC_014364.1 392083 393372 R COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: cbh:CLC_1414 sensor histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: Sensor histidine kinase; PFAM: histidine kinase; integral membrane sensor signal transduction histidine kinase complement(392083..393372) Spirochaeta smaragdinae DSM 11293 9488456 YP_003802129.1 CDS Spirs_0379 NC_014364.1 393567 394880 D COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: cdf:CD2078 amidohydrolase; PFAM: amidohydrolase; SPTR: uncharacterized protein; PFAM: Amidohydrolase family; amidohydrolase 393567..394880 Spirochaeta smaragdinae DSM 11293 9488457 YP_003802130.1 CDS Spirs_0380 NC_014364.1 394899 397403 D COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR000759:IPR012135:IPR013027:IPR001450:IPR 017896:IPR017900:IPR005720; KEGG: dal:Dalk_2523 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain; TIGRFAM: selenate reductase, YgfK subunit; dihydroorotate dehydrogenase (subfamily 1) family protein; dihydroorotate dehydrogenase 394899..397403 Spirochaeta smaragdinae DSM 11293 9488458 YP_003802131.1 CDS Spirs_0381 NC_014364.1 397539 397973 D KEGG: tme:Tmel_1130 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 397539..397973 Spirochaeta smaragdinae DSM 11293 9488459 YP_003802132.1 CDS Spirs_0382 NC_014364.1 398354 399511 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: tau:Tola_2293 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(398354..399511) Spirochaeta smaragdinae DSM 11293 9488460 YP_003802133.1 CDS Spirs_0383 NC_014364.1 399697 400305 R InterPro IPR001647; KEGG: mxa:MXAN_2869 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(399697..400305) Spirochaeta smaragdinae DSM 11293 9488461 YP_003802134.1 CDS Spirs_0384 NC_014364.1 400305 401180 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: dge:Dgeo_1140 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(400305..401180) Spirochaeta smaragdinae DSM 11293 9488462 YP_003802135.1 CDS Spirs_0385 NC_014364.1 401310 402113 D COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347:IPR002198; KEGG: cts:Ctha_1171 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 401310..402113 Spirochaeta smaragdinae DSM 11293 9488463 YP_003802136.1 CDS Spirs_0387 NC_014364.1 403843 404571 D KEGG: pfh:PFHG_04377 conserved hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 403843..404571 Spirochaeta smaragdinae DSM 11293 9488465 YP_003802137.1 CDS Spirs_0388 NC_014364.1 404568 405002 D KEGG: tgu:100220912 similar to coiled-coil domain containing 88A; SPTR: uncharacterized protein; hypothetical protein 404568..405002 Spirochaeta smaragdinae DSM 11293 9488466 YP_003802138.1 CDS Spirs_0389 NC_014364.1 405193 405876 D KEGG: sth:STH282 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 405193..405876 Spirochaeta smaragdinae DSM 11293 9488467 YP_003802139.1 CDS Spirs_0390 NC_014364.1 405873 406436 D KEGG: pcb:PC000842.02.0 structural maintenance of chromosome protein; SPTR: uncharacterized protein PY06369; hypothetical protein 405873..406436 Spirochaeta smaragdinae DSM 11293 9488468 YP_003802140.1 CDS Spirs_0391 NC_014364.1 406636 408267 D InterPro IPR000055:IPR007421; KEGG: mac:MA3410 hypothetical protein; PFAM: ATPase AAA; restriction modification system DNA specificity domain; SPTR: type I restriction-modification system M subunit; PFAM: Divergent AAA domain; type I restriction modification DNA specificity domain; transcriptional regulator 406636..408267 Spirochaeta smaragdinae DSM 11293 9488469 YP_003802141.1 CDS Spirs_0392 NC_014364.1 408462 409388 D KEGG: pfh:PFHG_03053 conserved hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 408462..409388 Spirochaeta smaragdinae DSM 11293 9488470 YP_003802142.1 CDS Spirs_0393 NC_014364.1 410187 410729 D InterPro IPR015032; KEGG: sun:SUN_2116 hypothetical protein; PFAM: Domain of unknown function DUF1863; SPTR: uncharacterized protein; PFAM: MTH538 TIR-like domain (DUF1863); hypothetical protein 410187..410729 Spirochaeta smaragdinae DSM 11293 9488471 YP_003802143.1 CDS Spirs_0394 NC_014364.1 410722 411363 D KEGG: mmq:MmarC5_1164 hypothetical protein; SPTR: Conserved hypothetical membrane protein; hypothetical protein 410722..411363 Spirochaeta smaragdinae DSM 11293 9488472 YP_003802144.1 CDS Spirs_0395 NC_014364.1 411620 411874 D KEGG: gfo:GFO_0860 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 411620..411874 Spirochaeta smaragdinae DSM 11293 9488473 YP_003802145.1 CDS Spirs_0396 NC_014364.1 411867 412292 D KEGG: gfo:GFO_3473 twitching motility protein PilT; SPTR: PIN domain containing protein; PFAM: PIN domain; twitching motility protein PilT 411867..412292 Spirochaeta smaragdinae DSM 11293 9488474 YP_003802146.1 CDS Spirs_0397 NC_014364.1 412660 413004 D InterPro IPR002934; KEGG: rca:Rcas_3922 DNA polymerase subunit beta; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain; DNA polymerase beta domain-containing protein region 412660..413004 Spirochaeta smaragdinae DSM 11293 9488475 YP_003802147.1 CDS Spirs_0398 NC_014364.1 412994 413389 D COGs: COG2250 conserved hypothetical protein related to C-terminal domain of eukaryotic chaperone SACSIN; InterPro IPR007842; KEGG: csc:Csac_0790 HEPN domain-containing protein; PFAM: HEPN domain protein; SMART: HEPN domain protein; SPTR: HEPN domain protein; PFAM: HEPN domain; HEPN domain-containing protein 412994..413389 Spirochaeta smaragdinae DSM 11293 9488476 YP_003802148.1 CDS Spirs_0399 NC_014364.1 414087 414989 D KEGG: ecb:100063761 Fanconi anemia, complementation group M; SPTR: glycosyltransferase; hypothetical protein 414087..414989 Spirochaeta smaragdinae DSM 11293 9488477 YP_003802149.1 CDS Spirs_0400 NC_014364.1 415134 416135 D KEGG: pvx:PVX_100940 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 415134..416135 Spirochaeta smaragdinae DSM 11293 9488478 YP_003802150.1 CDS Spirs_0402 NC_014364.1 417622 418287 D KEGG: dat:HRM2_19130 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 417622..418287 Spirochaeta smaragdinae DSM 11293 9488480 YP_003802151.1 CDS Spirs_0403 NC_014364.1 418563 419750 D COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR011579; KEGG: hya:HY04AAS1_1358 ATPase; PFAM: ATPase; SPTR: ATPase; PFAM: Archaeal ATPase; ATPase 418563..419750 Spirochaeta smaragdinae DSM 11293 9488481 YP_003802152.1 CDS Spirs_0404 NC_014364.1 419997 420905 D KEGG: scl:sce8483 hypothetical protein; SPTR: membrane protein; hypothetical protein 419997..420905 Spirochaeta smaragdinae DSM 11293 9488482 YP_003802153.1 CDS Spirs_0405 NC_014364.1 421116 421517 D KEGG: mmw:Mmwyl1_2728 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 421116..421517 Spirochaeta smaragdinae DSM 11293 9488483 YP_003802154.1 CDS Spirs_0406 NC_014364.1 421534 422013 D KEGG: ddi:DDBDRAFT_0218381 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 421534..422013 Spirochaeta smaragdinae DSM 11293 9488484 YP_003802155.1 CDS Spirs_0407 NC_014364.1 422207 422860 D InterPro IPR000126; KEGG: fsu:Fisuc_1304 hypothetical protein; SPTR: uncharacterized protein; PFAM: Trypsin; hypothetical protein 422207..422860 Spirochaeta smaragdinae DSM 11293 9488485 YP_003802156.1 CDS Spirs_0408 NC_014364.1 422857 423276 D KEGG: drm:Dred_3028 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 422857..423276 Spirochaeta smaragdinae DSM 11293 9488486 YP_003802157.1 CDS Spirs_0410 NC_014364.1 424835 425089 D KEGG: gfo:GFO_0860 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 424835..425089 Spirochaeta smaragdinae DSM 11293 9488488 YP_003802158.1 CDS Spirs_0411 NC_014364.1 425082 425507 D KEGG: gfo:GFO_3473 twitching motility protein PilT; SPTR: PIN domain containing protein; twitching motility protein PilT 425082..425507 Spirochaeta smaragdinae DSM 11293 9488489 YP_003802159.1 CDS Spirs_0413 NC_014364.1 426951 427907 D KEGG: ljf:FI9785_910 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 426951..427907 Spirochaeta smaragdinae DSM 11293 9488491 YP_003802160.1 CDS Spirs_0414 NC_014364.1 427961 428539 D COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: str:Sterm_2425 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 427961..428539 Spirochaeta smaragdinae DSM 11293 9488492 YP_003802161.1 CDS Spirs_0416 NC_014364.1 429322 430680 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cdf:CD2108 drug/sodium antiporter; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(429322..430680) Spirochaeta smaragdinae DSM 11293 9488494 YP_003802162.1 CDS Spirs_0417 NC_014364.1 431106 432038 D COGs: COG4405 conserved hypothetical protein; InterPro IPR000182:IPR007374; KEGG: cac:CAC1000 hypothetical protein; PFAM: protein of unknown function DUF437; GCN5-related N-acetyltransferase; SPTR: Uncharacterized protein, homolog of yhfF B.subtilis; PFAM: acetyltransferase (GNAT) family; ASCH domain; hypothetical protein 431106..432038 Spirochaeta smaragdinae DSM 11293 9488495 YP_003802163.1 CDS Spirs_0418 NC_014364.1 432219 433304 D COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: gur:Gura_4148 filamentation induced by cAMP protein Fic; PFAM: filamentation induced by cAMP protein Fic; SPTR: Filamentation induced by cAMP protein Fic; PFAM: Fic/DOC family; filamentation induced by cAMP protein Fic 432219..433304 Spirochaeta smaragdinae DSM 11293 9488496 YP_003802164.1 CDS Spirs_0419 NC_014364.1 433565 434089 D KEGG: abn:AB57_2683 hypothetical protein; SPTR: Predicted protein; hypothetical protein 433565..434089 Spirochaeta smaragdinae DSM 11293 9488497 YP_003802165.1 CDS Spirs_0422 NC_014364.1 435427 436113 R COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: pth:PTH_2232 transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(435427..436113) Spirochaeta smaragdinae DSM 11293 9488500 YP_003802166.1 CDS Spirs_0423 NC_014364.1 436135 436983 R COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tma:TM0326 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: Uncharacterized HTH-type transcriptional regulator TM_0326; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator complement(436135..436983) Spirochaeta smaragdinae DSM 11293 9488501 YP_003802167.1 CDS Spirs_0424 NC_014364.1 437035 437919 R COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR005829; KEGG: tpe:Tpen_1620 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase complement(437035..437919) Spirochaeta smaragdinae DSM 11293 9488502 YP_003802168.1 CDS Spirs_0425 NC_014364.1 438049 438990 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: amt:Amet_0892 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 438049..438990 Spirochaeta smaragdinae DSM 11293 9488503 YP_003802169.1 CDS Spirs_0426 NC_014364.1 439020 439793 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198; KEGG: ect:ECIAI39_0671 short-chain dehydrogenase/reductase SDR precursor; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 439020..439793 Spirochaeta smaragdinae DSM 11293 9488504 YP_003802170.1 CDS Spirs_0427 NC_014364.1 439877 440884 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: mjl:Mjls_2811 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 439877..440884 Spirochaeta smaragdinae DSM 11293 9488505 YP_003802171.1 CDS Spirs_0428 NC_014364.1 440891 441829 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: dtu:Dtur_1775 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 440891..441829 Spirochaeta smaragdinae DSM 11293 9488506 YP_003802172.1 CDS Spirs_0429 NC_014364.1 441826 442845 D COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: cpy:Cphy_0596 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein 441826..442845 Spirochaeta smaragdinae DSM 11293 9488507 YP_003802173.1 CDS Spirs_0430 NC_014364.1 442888 443364 D KEGG: dtu:Dtur_0299 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 442888..443364 Spirochaeta smaragdinae DSM 11293 9488508 YP_003802174.1 CDS Spirs_0431 NC_014364.1 443388 444878 D COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: tle:Tlet_1876 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein 443388..444878 Spirochaeta smaragdinae DSM 11293 9488509 YP_003802175.1 CDS Spirs_0432 NC_014364.1 444926 445663 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: amt:Amet_0818 GntR domain-containing protein; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 444926..445663 Spirochaeta smaragdinae DSM 11293 9488510 YP_003802176.1 CDS Spirs_0433 NC_014364.1 445787 447079 D KEGG: afn:Acfer_0081 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088); hypothetical protein 445787..447079 Spirochaeta smaragdinae DSM 11293 9488511 YP_003802177.1 CDS Spirs_0434 NC_014364.1 447218 447577 R KEGG: cal:CaO19.2504 bud site selection; SPTR: uncharacterized protein BMS1; hypothetical protein complement(447218..447577) Spirochaeta smaragdinae DSM 11293 9488512 YP_003802178.1 CDS Spirs_0437 NC_014364.1 449863 450792 D KEGG: edi:EDI_200050 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 449863..450792 Spirochaeta smaragdinae DSM 11293 9488515 YP_003802179.1 CDS Spirs_0438 NC_014364.1 451024 452208 R COGs: COG3328 transposase and inactivated derivatives; InterPro IPR001207; KEGG: glo:Glov_3450 transposase mutator type; PFAM: transposase mutator type; SPTR: transposase mutator type; PFAM: transposase, Mutator family; transposase mutator type complement(451024..452208) Spirochaeta smaragdinae DSM 11293 9488516 YP_003802180.1 CDS Spirs_0439 NC_014364.1 452371 453555 R COGs: COG1373 ATPase (AAA+ superfamily); InterPro IPR011579; KEGG: cbd:CBUD_0184 hypothetical ATPase; PFAM: ATPase; SPTR: Hypothetical ATPase; PFAM: Archaeal ATPase; ATPase complement(452371..453555) Spirochaeta smaragdinae DSM 11293 9488517 YP_003802181.1 CDS Spirs_0440 NC_014364.1 453745 454077 D InterPro IPR002514; KEGG: pvi:Cvib_1307 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase; transposase IS3/IS911 family protein 453745..454077 Spirochaeta smaragdinae DSM 11293 9488518 YP_003802182.1 CDS Spirs_0441 NC_014364.1 454074 454910 D COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: maq:Maqu_0236 integrase catalytic subunit; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain; Integrase catalytic subunit 454074..454910 Spirochaeta smaragdinae DSM 11293 9488519 YP_003802183.1 CDS Spirs_0442 NC_014364.1 455153 455608 D KEGG: gwc:GWCH70_1902 helicase C2; SPTR: transcriptional regulator, DeoR; hypothetical protein 455153..455608 Spirochaeta smaragdinae DSM 11293 9488520 YP_003802184.1 CDS Spirs_0443 NC_014364.1 456321 457676 D COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: cdl:CDR20291_1989 amidohydrolase; PFAM: amidohydrolase; SPTR: Probable amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase 456321..457676 Spirochaeta smaragdinae DSM 11293 9488522 YP_003802185.1 CDS Spirs_0444 NC_014364.1 457829 458212 D KEGG: lba:Lebu_1283 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2992); hypothetical protein 457829..458212 Spirochaeta smaragdinae DSM 11293 9488523 YP_003802186.1 CDS Spirs_0445 NC_014364.1 458231 458962 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: bsu:BSU16810 transcriptional regulator (GntR family); PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein ymfC; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(458231..458962) Spirochaeta smaragdinae DSM 11293 9488524 YP_003802187.1 CDS Spirs_0446 NC_014364.1 458978 459949 D InterProIPR001450:IPR008254:IPR017896:IPR017900:IPR 001226; KEGG: dol:Dole_1740 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: NADPH-dependent FMN reductase; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 458978..459949 Spirochaeta smaragdinae DSM 11293 9488525 YP_003802188.1 CDS Spirs_0447 NC_014364.1 460090 460380 D KEGG: tad:TRIADDRAFT_52854 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 460090..460380 Spirochaeta smaragdinae DSM 11293 9488526 YP_003802189.1 CDS Spirs_0448 NC_014364.1 460437 461189 D COGs: COG0778 nitroreductase; InterPro IPR000415:IPR020051; KEGG: ppd:Ppro_0543 hypothetical protein; PFAM: nitroreductase; SPTR: nitroreductase; TIGRFAM: SagB-type dehydrogenase domain; PFAM: nitroreductase family; TIGRFAM: SagB-type dehydrogenase domain; SagB-type dehydrogenase domain-containing protein 460437..461189 Spirochaeta smaragdinae DSM 11293 9488527 YP_003802190.1 CDS Spirs_0449 NC_014364.1 461155 461373 R hypothetical protein complement(461155..461373) Spirochaeta smaragdinae DSM 11293 9488528 YP_003802191.1 CDS Spirs_0450 NC_014364.1 461434 462717 D COGs: COG4277 DNA-binding protein with the Helix-hairpin-helix motif; InterPro IPR007197:IPR000532; KEGG: hmo:HM1_1854 radical sam domain protein, PFAM: radical SAM protein; SPTR: radical sam domain protein, ; PFAM: radical SAM superfamily; radical SAM protein 461434..462717 Spirochaeta smaragdinae DSM 11293 9488529 YP_003802192.1 CDS Spirs_0451 NC_014364.1 462717 463511 D KEGG: hor:Hore_05000 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 462717..463511 Spirochaeta smaragdinae DSM 11293 9488530 YP_003802193.1 CDS Spirs_0452 NC_014364.1 463605 464882 R COGs: COG1760 L-serine deaminase; InterPro IPR005131:IPR005130; KEGG: app:CAP2UW1_0154 serine dehydratase alpha chain; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; PRIAM: L-serine ammonia-lyase; SPTR: serine dehydratase alpha chain; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; TIGRFAM: L-serine dehydratase, iron-sulfur-dependent, single chain form; L-serine ammonia-lyase complement(463605..464882) Spirochaeta smaragdinae DSM 11293 9488531 YP_003802194.1 CDS Spirs_0453 NC_014364.1 464885 465736 R COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013:IPR010140; KEGG: tro:trd_A0397 histidinol-phosphatase; PFAM: PHP domain protein; SPTR: histidinol-phosphatase; TIGRFAM: histidinol phosphate phosphatase HisJ family; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; HisJ family histidinol phosphate phosphatase complement(464885..465736) Spirochaeta smaragdinae DSM 11293 9488532 YP_003802195.1 CDS Spirs_0454 NC_014364.1 465748 466323 R COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: hmo:HM1_3019 nitroreductase family protein; PFAM: nitroreductase; SPTR: nitroreductase family protein; PFAM: nitroreductase family; nitroreductase complement(465748..466323) Spirochaeta smaragdinae DSM 11293 9488533 YP_003802196.1 CDS Spirs_0455 NC_014364.1 466443 467441 D COGs: COG0714 MoxR-like ATPase; InterPro IPR011703:IPR016366; KEGG: btu:BT0176 MoxR protein; PFAM: ATPase associated with various cellular activities AAA_3; SPTR: MoxR protein; PFAM: ATPase family associated with various cellular activities (AAA); ATPase AAA 466443..467441 Spirochaeta smaragdinae DSM 11293 9488534 YP_003802197.1 CDS Spirs_0456 NC_014364.1 467447 468319 D COGs: COG1721 conserved hypothetical protein (some members contain a von Willebrand factor A (vWA) domain); InterPro IPR002881; KEGG: hau:Haur_4903 hypothetical protein; PFAM: protein of unknown function DUF58; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF58; hypothetical protein 467447..468319 Spirochaeta smaragdinae DSM 11293 9488535 YP_003802198.1 CDS Spirs_0457 NC_014364.1 468316 469230 D KEGG: bdu:BDU_173 hypothetical protein; SPTR: Uncharacterized conserved protein; hypothetical protein 468316..469230 Spirochaeta smaragdinae DSM 11293 9488536 YP_003802199.1 CDS Spirs_0458 NC_014364.1 469227 470228 D InterPro IPR002035; KEGG: bhr:BH0173 hypothetical membrane spanning protein; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: Hypothetical membrane spanning protein; PFAM: von Willebrand factor A domain; von Willebrand factor A 469227..470228 Spirochaeta smaragdinae DSM 11293 9488537 YP_003802200.1 CDS Spirs_0459 NC_014364.1 470228 471202 D InterPro IPR002035; KEGG: cpi:Cpin_0906 von Willebrand factor A; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: von Willebrand factor A domain protein; PFAM: von Willebrand factor A domain; von Willebrand factor A 470228..471202 Spirochaeta smaragdinae DSM 11293 9488538 YP_003802201.1 CDS Spirs_0460 NC_014364.1 471187 471777 D InterPro IPR019734:IPR001440:IPR013105:IPR013026; KEGG: bbu:BB0171 hypothetical protein; PFAM: hypothetical protein; hypothetical protein; SPTR: uncharacterized protein; PFAM: Tetratricopeptide repeat; hypothetical protein 471187..471777 Spirochaeta smaragdinae DSM 11293 9488539 YP_003802202.1 CDS Spirs_0461 NC_014364.1 471771 473783 D InterPro IPR013026; KEGG: bga:BG0169 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 471771..473783 Spirochaeta smaragdinae DSM 11293 9488540 YP_003802203.1 CDS Spirs_0462 NC_014364.1 473785 474258 D COGs: COG2840 conserved hypothetical protein; InterPro IPR002625; KEGG: tde:TDE1254 Smr domain-containing protein; PFAM: Smr protein/MutS2; SMART: Smr protein/MutS2; SPTR: Smr domain protein; PFAM: Smr domain; Smr protein/MutS2 473785..474258 Spirochaeta smaragdinae DSM 11293 9488541 YP_003802204.1 CDS Spirs_0463 NC_014364.1 474269 474487 R COGs: COG0361 translation initiation factor 1 (IF-1); InterPro IPR006196:IPR004368; KEGG: tde:TDE2087 translation initiation factor IF-1; PFAM: S1 IF1 family protein; SPTR: translation initiation factor IF-1; TIGRFAM: translation initiation factor IF-1; PFAM: translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1; translation initiation factor IF-1 complement(474269..474487) Spirochaeta smaragdinae DSM 11293 9488542 YP_003802205.1 CDS Spirs_0464 NC_014364.1 474624 474980 D COGs: COG1734 DnaK suppressor protein; InterPro IPR020460:IPR000962; KEGG: tpp:TPASS_0096 DnaK suppressor; PFAM: zinc finger DksA/TraR C4-type; SPTR: DnaK suppressor, ; PFAM: Prokaryotic dksA/traR C4-type zinc finger; TIGRFAM: RNA polymerase-binding protein DksA; TraR/DksA family transcriptional regulator 474624..474980 Spirochaeta smaragdinae DSM 11293 9488543 YP_003802206.1 CDS Spirs_0465 NC_014364.1 475044 475451 D KEGG: tde:TDE1987 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 475044..475451 Spirochaeta smaragdinae DSM 11293 9488544 YP_003802207.1 CDS Spirs_0466 NC_014364.1 475458 476126 R COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: dap:Dacet_1446 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(475458..476126) Spirochaeta smaragdinae DSM 11293 9488545 YP_003802208.1 CDS Spirs_0467 NC_014364.1 476151 477119 D KEGG: tcr:505171.70 ATP-dependent DEAD/H RNA helicase; SPTR: ATP-dependent DEAD/H RNA helicase; hypothetical protein 476151..477119 Spirochaeta smaragdinae DSM 11293 9488546 YP_003802209.1 CDS Spirs_0468 NC_014364.1 477135 478637 R COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR005580:IPR000504:IPR014021; KEGG: cby:CLM_3166 ATP-dependent RNA helicase, DEAD/DEAH box family; PFAM: DbpA RNA-binding domain protein; DEAD/DEAH box helicase; SPTR: ATP-dependent RNA helicase, DEAD/DEAH box family; PFAM: DbpA RNA binding domain; DEAD/DEAH box helicase; DbpA RNA-binding domain-containing protein complement(477135..478637) Spirochaeta smaragdinae DSM 11293 9488547 YP_003802210.1 CDS Spirs_0469 NC_014364.1 478721 479938 D COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tpp:TPASS_0292 outer membrane protein TpN50; PFAM: OmpA/MotB domain protein; SPTR: OmpA family protein; PFAM: OmpA family; OmpA/MotB domain-containing protein 478721..479938 Spirochaeta smaragdinae DSM 11293 9488548 YP_003802211.1 CDS Spirs_0470 NC_014364.1 480006 480650 D KEGG: cte:CT1380 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 480006..480650 Spirochaeta smaragdinae DSM 11293 9488549 YP_003802212.1 CDS Spirs_0471 NC_014364.1 480678 481064 D KEGG: pop:POPTR_833422 hypothetical protein; SPTR: membrane protein-like protein; hypothetical protein 480678..481064 Spirochaeta smaragdinae DSM 11293 9488550 YP_003802213.1 CDS Spirs_0472 NC_014364.1 481076 482224 D KEGG: lbz:LbrM20_V2.2080 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 481076..482224 Spirochaeta smaragdinae DSM 11293 9488551 YP_003802214.1 CDS Spirs_0473 NC_014364.1 482221 483474 D COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: tsi:TSIB_0467 probable hydroxymethylpyrimidine transporter CytX; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: Probable hydroxymethylpyrimidine transporter CytX; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: NCS1 nucleoside transporter family; probable hydroxymethylpyrimidine transporter CytX; cytosine/purines uracil thiamine allantoin permease 482221..483474 Spirochaeta smaragdinae DSM 11293 9488552 YP_003802215.1 CDS Spirs_0474 NC_014364.1 483667 485457 R COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR001041:IPR019574:IPR001450:IPR004108:IPR 003149:IPR017896:IPR017900:IPR000283:IPR013352; KEGG: dae:Dtox_0172 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; SPTR: hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 2Fe-2S iron-sulfur cluster binding domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only; NAD(P)-dependent iron-only hydrogenase catalytic subunit complement(483667..485457) Spirochaeta smaragdinae DSM 11293 9488553 YP_003802216.1 CDS Spirs_0475 NC_014364.1 485454 488576 R COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR013027:IPR000103:IPR002023:IPR011538:IPR 019554:IPR019575:IPR019794:IPR001949; KEGG: dal:Dalk_2559 respiratory-chain NADH dehydrogenase domain 51 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Pyridine nucleotide-disulphide oxidoreductase; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; Respiratory-chain NADH dehydrogenase domain 51 kDa subunit complement(485454..488576) Spirochaeta smaragdinae DSM 11293 9488554 YP_003802217.1 CDS Spirs_0476 NC_014364.1 488573 489061 R COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: pth:PTH_2649 NADH:ubiquinone oxidoreductase 24 kD subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: NADH:ubiquinone oxidoreductase 24 kD subunit; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; NADH dehydrogenase (ubiquinone) 24 kDa subunit complement(488573..489061) Spirochaeta smaragdinae DSM 11293 9488555 YP_003802218.1 CDS Spirs_0477 NC_014364.1 489283 492117 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 001789:IPR004358:IPR013767:IPR008207:IPR005467:IPR000700; KEGG: dma:DMR_25470 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; response regulator receiver; Hpt domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor hybrid histidine kinase 489283..492117 Spirochaeta smaragdinae DSM 11293 9488556 YP_003802219.1 CDS Spirs_0478 NC_014364.1 492119 493069 R KEGG: cai:Caci_0770 succinate dehydrogenase or fumarate reductase, flavoprotein subunit; SPTR: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; hypothetical protein complement(492119..493069) Spirochaeta smaragdinae DSM 11293 9488557 YP_003802220.1 CDS Spirs_0479 NC_014364.1 493094 493921 R COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544; KEGG: dat:HRM2_24560 IlvE; PFAM: aminotransferase class IV; SPTR: IlvE; PFAM: Aminotransferase class IV; class IV aminotransferase complement(493094..493921) Spirochaeta smaragdinae DSM 11293 9488558 YP_003802221.1 CDS Spirs_0480 NC_014364.1 493925 494863 R COGs: COG1171 threonine dehydratase; InterPro IPR001926:IPR000634; KEGG: tgr:Tgr7_1148 serine/threonine dehydratase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: serine/threonine dehydratase; PFAM: pyridoxal-phosphate dependent enzyme; pyridoxal-5'-phosphate-dependent protein subunit beta complement(493925..494863) Spirochaeta smaragdinae DSM 11293 9488559 YP_003802222.1 CDS Spirs_0481 NC_014364.1 495099 495815 D InterPro IPR007272; KEGG: tit:Thit_0076 protein of unknown function DUF395 YeeE/YedE; PFAM: protein of unknown function DUF395 YeeE/YedE; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395); hypothetical protein 495099..495815 Spirochaeta smaragdinae DSM 11293 9488560 YP_003802223.1 CDS Spirs_0482 NC_014364.1 495835 496062 D InterPro IPR001455; KEGG: smf:Smon_0718 SirA family protein; PFAM: SirA family protein; SPTR: SirA family protein; PFAM: SirA-like protein; SirA family protein 495835..496062 Spirochaeta smaragdinae DSM 11293 9488561 YP_003802224.1 CDS Spirs_0483 NC_014364.1 496082 496615 D InterPro IPR007272; KEGG: tit:Thit_0078 protein of unknown function DUF395 YeeE/YedE; PFAM: protein of unknown function DUF395 YeeE/YedE; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395); hypothetical protein 496082..496615 Spirochaeta smaragdinae DSM 11293 9488562 YP_003802225.1 CDS Spirs_0484 NC_014364.1 496641 497879 D COGs: COG0492 thioredoxin reductase; InterPro IPR000103:IPR013027; KEGG: tit:Thit_0079 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: thioredoxin; Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 496641..497879 Spirochaeta smaragdinae DSM 11293 9488563 YP_003802226.1 CDS Spirs_0485 NC_014364.1 497963 498397 R COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: tde:TDE1029 HSP20/alpha crystallin family protein; PFAM: heat shock protein Hsp20; SPTR: Small heat shock protein; PFAM: Hsp20/alpha crystallin family; heat shock protein Hsp20 complement(497963..498397) Spirochaeta smaragdinae DSM 11293 9488564 YP_003802227.1 CDS Spirs_0486 NC_014364.1 498638 499564 R COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR003710; KEGG: gbm:Gbem_0788 2-dehydropantoate 2-reductase; PFAM: ketopantoate reductase; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase; 2-dehydropantoate 2-reductase complement(498638..499564) Spirochaeta smaragdinae DSM 11293 9488565 YP_003802228.1 CDS Spirs_0487 NC_014364.1 499738 501561 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE0181 methyl-accepting chemotaxis protein; PFAM: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; SMART: histidine kinase HAMP region domain protein; chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 499738..501561 Spirochaeta smaragdinae DSM 11293 9488566 YP_003802229.1 CDS Spirs_0488 NC_014364.1 501632 502744 R COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tte:TTE1351 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase complement(501632..502744) Spirochaeta smaragdinae DSM 11293 9488567 YP_003802230.1 CDS Spirs_0489 NC_014364.1 502897 504315 D COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: tna:CTN_1540 sugar:cation symporter family protein; PFAM: major facilitator superfamily MFS_1; SPTR: Sugar:cation symporter family protein; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 502897..504315 Spirochaeta smaragdinae DSM 11293 9488568 YP_003802231.1 CDS Spirs_0490 NC_014364.1 504323 504907 R KEGG: wpi:WPa_0135 tRNA delta(2)-isopentenylpyrophosphate transferase; SPTR: uncharacterized protein; hypothetical protein complement(504323..504907) Spirochaeta smaragdinae DSM 11293 9488569 YP_003802232.1 CDS Spirs_0491 NC_014364.1 504980 505705 D COGs: COG0622 phosphoesterase; InterPro IPR004843:IPR011152; KEGG: tro:trd_1481 phosphatase family protein; PFAM: metallophosphoesterase; SPTR: phosphatase family protein; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase 504980..505705 Spirochaeta smaragdinae DSM 11293 9488570 YP_003802233.1 CDS Spirs_0492 NC_014364.1 505825 507822 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE2783 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 505825..507822 Spirochaeta smaragdinae DSM 11293 9488571 YP_003802234.1 CDS Spirs_0493 NC_014364.1 507851 509059 D InterPro IPR004740; KEGG: csa:Csal_0765 nucleoside:H+ symporter; PFAM: nucleoside:H symporter; SPTR: nucleoside:H+ symporter; PFAM: nucleoside H+ symporter; TIGRFAM: nucleoside transporter; nucleoside:H symporter 507851..509059 Spirochaeta smaragdinae DSM 11293 9488572 YP_003802235.1 CDS Spirs_0494 NC_014364.1 509028 510341 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR001789:IPR003593:IPR020441:IPR002078:IPR 002197; KEGG: aoe:Clos_1079 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; ATPase AAA; SPTR: Two component, sigma54 specific, Fis family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Fis family transcriptional regulator complement(509028..510341) Spirochaeta smaragdinae DSM 11293 9488573 YP_003802236.1 CDS Spirs_0495 NC_014364.1 510348 511619 R COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transporter; InterPro IPR003661:IPR003594:IPR004358:IPR005467; KEGG: ank:AnaeK_0446 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase complement(510348..511619) Spirochaeta smaragdinae DSM 11293 9488574 YP_003802237.1 CDS Spirs_0496 NC_014364.1 511616 512305 R COGs: COG4902 conserved hypothetical protein; InterPro IPR019243; KEGG: mvu:Metvu_0451 protein of unknown function DUF2202; PFAM: protein of unknown function DUF2202; SPTR: uncharacterized protein; PFAM: Uncharacterized protein domain (DUF2202); hypothetical protein complement(511616..512305) Spirochaeta smaragdinae DSM 11293 9488575 YP_003802238.1 CDS Spirs_0497 NC_014364.1 512314 513048 R KEGG: tte:TTE1095 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(512314..513048) Spirochaeta smaragdinae DSM 11293 9488576 YP_003802239.1 CDS Spirs_0498 NC_014364.1 513045 513881 R COGs: COG0348 polyferredoxin; InterPro IPR017896:IPR017900; KEGG: tte:TTE1096 polyferredoxin; SPTR: polyferredoxin; polyferredoxin complement(513045..513881) Spirochaeta smaragdinae DSM 11293 9488577 YP_003802240.1 CDS Spirs_0499 NC_014364.1 513975 514448 R KEGG: hsa:10929 splicing factor, arginine/serine-rich 2B; SPTR: Splicing factor, arginine/serine-rich 2B; hypothetical protein complement(513975..514448) Spirochaeta smaragdinae DSM 11293 9488578 YP_003802241.1 CDS Spirs_0500 NC_014364.1 514617 515876 R COGs: COG4992 ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: hor:Hore_14780 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III; class III aminotransferase complement(514617..515876) Spirochaeta smaragdinae DSM 11293 9488579 YP_003802242.1 CDS Spirs_0501 NC_014364.1 515857 517845 R COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: gym:GYMC10_0623 peptidase U32; PFAM: peptidase U32; SPTR: peptidase U32; PFAM: peptidase family U32; peptidase U32 complement(515857..517845) Spirochaeta smaragdinae DSM 11293 9488580 YP_003802243.1 CDS Spirs_0502 NC_014364.1 517928 518329 R KEGG: aco:Amico_0361 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(517928..518329) Spirochaeta smaragdinae DSM 11293 9488581 YP_003802244.1 CDS Spirs_0503 NC_014364.1 518326 519480 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: aco:Amico_0360 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(518326..519480) Spirochaeta smaragdinae DSM 11293 9488582 YP_003802245.1 CDS Spirs_0504 NC_014364.1 519484 520533 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: tai:Taci_0122 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(519484..520533) Spirochaeta smaragdinae DSM 11293 9488583 YP_003802246.1 CDS Spirs_0505 NC_014364.1 520538 522139 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: tai:Taci_0121 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(520538..522139) Spirochaeta smaragdinae DSM 11293 9488584 YP_003802247.1 CDS Spirs_0506 NC_014364.1 522225 523445 R KEGG: tai:Taci_0120 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(522225..523445) Spirochaeta smaragdinae DSM 11293 9488585 YP_003802248.1 CDS Spirs_0508 NC_014364.1 524921 525706 R COGs: COG1414 transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: afl:Aflv_1569 transcriptional regulator (IclR family); PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: transcriptional regulator (IclR family); PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator complement(524921..525706) Spirochaeta smaragdinae DSM 11293 9488587 YP_003802249.1 CDS Spirs_0509 NC_014364.1 526369 527253 D COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006183:IPR006115:IPR002204:IPR006398; KEGG: dsy:DSY4169 tartronate semialdehyde reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; 2-hydroxy-3-oxopropionate reductase 526369..527253 Spirochaeta smaragdinae DSM 11293 9488588 YP_003802250.1 CDS Spirs_0510 NC_014364.1 527255 528175 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR020625; KEGG: bld:BLi03702 hypothetical protein; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 527255..528175 Spirochaeta smaragdinae DSM 11293 9488589 YP_003802251.1 CDS Spirs_0511 NC_014364.1 528203 528679 D KEGG: afn:Acfer_1103 hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctB family; hypothetical protein 528203..528679 Spirochaeta smaragdinae DSM 11293 9488590 YP_003802252.1 CDS Spirs_0512 NC_014364.1 528692 530179 D COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: afn:Acfer_1102 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein 528692..530179 Spirochaeta smaragdinae DSM 11293 9488591 YP_003802253.1 CDS Spirs_0513 NC_014364.1 530219 531190 D COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: asu:Asuc_1849 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Uncharacterized protein UPF0065; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein 530219..531190 Spirochaeta smaragdinae DSM 11293 9488592 YP_003802254.1 CDS Spirs_0514 NC_014364.1 531275 532474 D COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR001176:IPR004839:IPR004838; KEGG: gym:GYMC10_4661 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: aspartate transaminase; PFAM: Aminotransferase class I and II; class I and II aminotransferase 531275..532474 Spirochaeta smaragdinae DSM 11293 9488593 YP_003802255.1 CDS Spirs_0515 NC_014364.1 532648 534744 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR016160; KEGG: dba:Dbac_1421 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(532648..534744) Spirochaeta smaragdinae DSM 11293 9488594 YP_003802256.1 CDS Spirs_0516 NC_014364.1 534840 535529 R COGs: COG0566 rRNA methylase; InterPro IPR001537; KEGG: ter:Tery_2249 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: tRNA/rRNA methyltransferase (SpoU); PFAM: SpoU rRNA methylase family; tRNA/rRNA methyltransferase SpoU complement(534840..535529) Spirochaeta smaragdinae DSM 11293 9488595 YP_003802257.1 CDS Spirs_0517 NC_014364.1 535646 536278 D KEGG: dat:HRM2_02050 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 535646..536278 Spirochaeta smaragdinae DSM 11293 9488596 YP_003802258.1 CDS Spirs_0518 NC_014364.1 536275 538161 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211:IPR000408; KEGG: dat:HRM2_02030 Adh3; PFAM: iron-containing alcohol dehydrogenase; SPTR: Adh3; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 536275..538161 Spirochaeta smaragdinae DSM 11293 9488597 YP_003802259.1 CDS Spirs_0519 NC_014364.1 538182 539159 D COGs: COG3272 conserved hypothetical protein; InterPro IPR007553:IPR013560; KEGG: sat:SYN_02271 cytoplasmic protein; PFAM: protein of unknown function DUF1722; protein of unknown function DUF523; SPTR: Hypothetical cytosolic protein; PFAM: protein of unknown function (DUF523); protein of unknown function (DUF1722); hypothetical protein 538182..539159 Spirochaeta smaragdinae DSM 11293 9488598 YP_003802260.1 CDS Spirs_0520 NC_014364.1 539274 539981 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR008920:IPR011711; KEGG: cpy:Cphy_1561 regulatory protein GntR HTH; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; fatty acid responsive transcription factor FadR domain protein; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 539274..539981 Spirochaeta smaragdinae DSM 11293 9488599 YP_003802261.1 CDS Spirs_0521 NC_014364.1 540014 540622 D KEGG: mmp:MMP0106 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 540014..540622 Spirochaeta smaragdinae DSM 11293 9488600 YP_003802262.1 CDS Spirs_0522 NC_014364.1 540628 541689 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: tpp:TPASS_0981 sensory transduction histidine kinase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: sensory transduction histidine kinase, ; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(540628..541689) Spirochaeta smaragdinae DSM 11293 9488601 YP_003802263.1 CDS Spirs_0523 NC_014364.1 541761 542432 D COGs: COG2940 proteins containing SET domain; InterPro IPR001214; KEGG: dol:Dole_0979 nuclear protein SET; PFAM: nuclear protein SET; SMART: nuclear protein SET; SPTR: Nuclear protein SET; PFAM: SET domain; nuclear protein SET 541761..542432 Spirochaeta smaragdinae DSM 11293 9488602 YP_003802264.1 CDS Spirs_0524 NC_014364.1 542489 543244 R COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: bpu:BPUM_3298 glutamine ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(542489..543244) Spirochaeta smaragdinae DSM 11293 9488603 YP_003802265.1 CDS Spirs_0525 NC_014364.1 543231 543908 R COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: dsa:Desal_3318 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane protein complement(543231..543908) Spirochaeta smaragdinae DSM 11293 9488604 YP_003802266.1 CDS Spirs_0526 NC_014364.1 543921 544694 R COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638:IPR018313; KEGG: dsa:Desal_3319 extracellular solute-binding protein family 3; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: extracellular solute-binding protein family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein complement(543921..544694) Spirochaeta smaragdinae DSM 11293 9488605 YP_003802267.1 CDS Spirs_0527 NC_014364.1 545158 546096 D InterPro IPR004010; KEGG: ilo:IL0202 methyl-accepting chemotaxis protein; PFAM: Cache domain protein; SPTR: methyl-accepting chemotaxis protein (HAMP, Cache domains); PFAM: Cache domain; Cache domain-containing protein 545158..546096 Spirochaeta smaragdinae DSM 11293 9488606 YP_003802268.1 CDS Spirs_0528 NC_014364.1 546099 546896 D COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR005467; KEGG: rca:Rcas_4226 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: integral membrane sensor signal transduction histidine kinase; manually curated; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; histidine kinase 546099..546896 Spirochaeta smaragdinae DSM 11293 9488607 YP_003802269.1 CDS Spirs_0529 NC_014364.1 546893 547543 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cpi:Cpin_4160 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 546893..547543 Spirochaeta smaragdinae DSM 11293 9488608 YP_003802270.1 CDS Spirs_0530 NC_014364.1 547662 548954 D COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991:IPR018107; KEGG: aco:Amico_0277 sodium:dicarboxylate symporter; PFAM: sodium:dicarboxylate symporter; SPTR: Proton/sodium-glutamate symport protein; PFAM: Sodium:dicarboxylate symporter family; sodium:dicarboxylate symporter 547662..548954 Spirochaeta smaragdinae DSM 11293 9488609 YP_003802271.1 CDS Spirs_0531 NC_014364.1 549026 550228 R COGs: COG2814 Arabinose efflux permease; InterPro IPR001958:IPR011701; KEGG: sti:Sthe_3125 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(549026..550228) Spirochaeta smaragdinae DSM 11293 9488610 YP_003802272.1 CDS Spirs_0532 NC_014364.1 550315 551556 D COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR000241:IPR002052; KEGG: sfu:Sfum_1764 RNA methylase; PFAM: RNA methylase; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: RNA methylase; PFAM: RNA methylase family UPF0020; rRNA (guanine-N(2)-)-methyltransferase 550315..551556 Spirochaeta smaragdinae DSM 11293 9488611 YP_003802273.1 CDS Spirs_0533 NC_014364.1 551553 552404 R COGs: COG1814 Uncharacterized membrane protein; InterPro IPR003251:IPR008217; KEGG: hor:Hore_01890 uncharacterized membrane protein; PFAM: protein of unknown function DUF125 transmembrane; rubrerythrin; SPTR: Uncharacterized membrane protein; PFAM: rubrerythrin; VIT family; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; hypothetical protein complement(551553..552404) Spirochaeta smaragdinae DSM 11293 9488612 YP_003802274.1 CDS Spirs_0534 NC_014364.1 552472 555630 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR001610:IPR003661:IPR003594:IPR 004358:IPR013767:IPR013655:IPR005467:IPR000700; KEGG: mgm:Mmc1_2953 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor signal transduction histidine kinase complement(552472..555630) Spirochaeta smaragdinae DSM 11293 9488613 YP_003802275.1 CDS Spirs_0535 NC_014364.1 555701 556717 D COGs: COG2334 homoserine kinase type II (protein kinase fold); InterPro IPR002575; KEGG: dps:DP2064 hypothetical protein; PFAM: aminoglycoside phosphotransferase; SPTR: Aminoglycoside phosphotransferase; PFAM: phosphotransferase enzyme family; aminoglycoside phosphotransferase 555701..556717 Spirochaeta smaragdinae DSM 11293 9488614 YP_003802276.1 CDS Spirs_0536 NC_014364.1 556705 557469 R InterPro IPR009875; KEGG: efa:EF0505 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; PFAM: PilZ domain; type IV pilus assembly PilZ complement(556705..557469) Spirochaeta smaragdinae DSM 11293 9488615 YP_003802277.1 CDS Spirs_0537 NC_014364.1 557537 558058 D COGs: COG0693 intracellular protease/amidase; InterPro IPR002818:IPR006286; KEGG: oih:OB0506 intracellular proteinase; PFAM: ThiJ/PfpI domain protein; SPTR: C56 family peptidase; TIGRFAM: intracellular protease PfpI family; PFAM: DJ-1/PfpI family; TIGRFAM: intracellular protease PfpI family; intracellular protease PfpI family 557537..558058 Spirochaeta smaragdinae DSM 11293 9488616 YP_003802278.1 CDS Spirs_0538 NC_014364.1 558067 558948 R InterPro IPR000620; KEGG: dal:Dalk_4084 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family; hypothetical protein complement(558067..558948) Spirochaeta smaragdinae DSM 11293 9488617 YP_003802279.1 CDS Spirs_0540 NC_014364.1 559423 560340 D KEGG: plu:plu0156 hypothetical protein; SPTR: Unknown protein; hypothetical protein 559423..560340 Spirochaeta smaragdinae DSM 11293 9488619 YP_003802280.1 CDS Spirs_0541 NC_014364.1 560751 561938 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495:IPR005467; KEGG: mth:MTH985 sensory transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: sensory transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 560751..561938 Spirochaeta smaragdinae DSM 11293 9488621 YP_003802281.1 CDS Spirs_0542 NC_014364.1 561961 563157 D COGs: COG2357 conserved hypothetical protein; InterProIPR019734:IPR007685:IPR001440:IPR013105:IPR 013026; KEGG: tde:TDE1711 RelA/SpoT domain-containing protein; PFAM: RelA/SpoT domain protein; hypothetical protein; Tetratricopeptide TPR_2 repeat protein; SPTR: RelA/SpoT domain protein; PFAM: Region found in RelA / SpoT proteins; Tetratricopeptide repeat; RelA/SpoT domain-containing protein 561961..563157 Spirochaeta smaragdinae DSM 11293 9488622 YP_003802282.1 CDS Spirs_0543 NC_014364.1 563138 564049 R KEGG: ctc:CTC02044 Ser/Thr and Tyr protein phosphatase (dual specificity)#; SPTR: uncharacterized protein; hypothetical protein complement(563138..564049) Spirochaeta smaragdinae DSM 11293 9488623 YP_003802283.1 CDS Spirs_0544 NC_014364.1 564053 565246 R COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR000385; KEGG: sfu:Sfum_2252 radical SAM domain-containing protein; PFAM: radical SAM protein; SPTR: radical SAM domain protein; PFAM: radical SAM superfamily; radical SAM protein complement(564053..565246) Spirochaeta smaragdinae DSM 11293 9488624 YP_003802284.1 CDS Spirs_0545 NC_014364.1 565251 566075 R COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002347:IPR002198; KEGG: sus:acid_0989 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(565251..566075) Spirochaeta smaragdinae DSM 11293 9488625 YP_003802285.1 CDS Spirs_0546 NC_014364.1 566167 567402 D COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cac:CAC0864 histidine kinase-like ATPase; PFAM: ATP-binding region ATPase domain protein; SPTR: histidine kinase-like ATPase; PFAM: histidine kinase; signal transduction histidine kinase 566167..567402 Spirochaeta smaragdinae DSM 11293 9488626 YP_003802286.1 CDS Spirs_0547 NC_014364.1 567402 568073 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cac:CAC0865 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 567402..568073 Spirochaeta smaragdinae DSM 11293 9488627 YP_003802287.1 CDS Spirs_0548 NC_014364.1 568180 569481 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059:IPR006061; KEGG: mmw:Mmwyl1_1651 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Secreted sugar-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 568180..569481 Spirochaeta smaragdinae DSM 11293 9488628 YP_003802288.1 CDS Spirs_0549 NC_014364.1 569551 570477 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hau:Haur_4034 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type sugar transport system permease; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 569551..570477 Spirochaeta smaragdinae DSM 11293 9488629 YP_003802289.1 CDS Spirs_0550 NC_014364.1 570480 571328 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bbe:BBR47_13430 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporter inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 570480..571328 Spirochaeta smaragdinae DSM 11293 9488630 YP_003802290.1 CDS Spirs_0551 NC_014364.1 571522 575847 D COGs: COG3581 conserved hypothetical protein; InterPro IPR002731:IPR018709:IPR008275; KEGG: cth:Cthe_1329 CoA-substrate-specific enzyme activase; PFAM: protein of unknown function DUF2229, CoA enzyme activase; ATPase BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA-substrate-specific enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase; CoA-substrate-specific enzyme activase 571522..575847 Spirochaeta smaragdinae DSM 11293 9488631 YP_003802291.1 CDS Spirs_0552 NC_014364.1 575820 576467 R COGs: COG0797 Lipoprotein; InterPro IPR005132:IPR007730:IPR012997; KEGG: dal:Dalk_2877 lipoprotein A; PFAM: Rare lipoprotein A; sporulation domain protein; SPTR: Rare lipoprotein A; TIGRFAM: lipoprotein A; PFAM: Rare lipoprotein A (RlpA)-like double-psi beta-barrel; sporulation related domain; TIGRFAM: rare lipoprotein A; lipoprotein A complement(575820..576467) Spirochaeta smaragdinae DSM 11293 9488632 YP_003802292.1 CDS Spirs_0553 NC_014364.1 576464 577324 R COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: sma:SAV_6654 sugar ABC transporter permease; PFAM: inner-membrane translocator; SPTR: simple sugar ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(576464..577324) Spirochaeta smaragdinae DSM 11293 9488633 YP_003802293.1 CDS Spirs_0554 NC_014364.1 577321 578328 R COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: kol:Kole_1835 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(577321..578328) Spirochaeta smaragdinae DSM 11293 9488634 YP_003802294.1 CDS Spirs_0555 NC_014364.1 578325 579887 R COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: bsu:BSU31550 carbohydrate ABC transporter (ATP-binding protein); PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: Uncharacterized ABC transporter ATP-binding protein yufO; PFAM: ABC transporter; ABC transporter complement(578325..579887) Spirochaeta smaragdinae DSM 11293 9488635 YP_003802295.1 CDS Spirs_0556 NC_014364.1 579892 580950 R COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: tde:TDE0951 lipoprotein; PFAM: basic membrane lipoprotein; SPTR: Lipoprotein, ; PFAM: Basic membrane protein; basic membrane lipoprotein complement(579892..580950) Spirochaeta smaragdinae DSM 11293 9488636 YP_003802296.1 CDS Spirs_0557 NC_014364.1 581281 582519 D COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: tde:TDE2723 phosphoribosylpyrophosphate synthetase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: phosphoribosylpyrophosphate synthetase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; ribose-phosphate pyrophosphokinase 581281..582519 Spirochaeta smaragdinae DSM 11293 9488637 YP_003802297.1 CDS Spirs_0558 NC_014364.1 582529 583998 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: sna:Snas_4064 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 582529..583998 Spirochaeta smaragdinae DSM 11293 9488638 YP_003802298.1 CDS Spirs_0559 NC_014364.1 583973 584704 R COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: cpc:Cpar_0675 protein of unknown function DUF45; PFAM: protein of unknown function DUF45; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF45; hypothetical protein complement(583973..584704) Spirochaeta smaragdinae DSM 11293 9488639 YP_003802299.1 CDS Spirs_0560 NC_014364.1 584764 586671 D InterPro IPR002931; KEGG: tye:THEYE_A1896 hypothetical protein; PFAM: transglutaminase; SMART: transglutaminase domain protein; SPTR: uncharacterized protein; PFAM: transglutaminase-like superfamily; transglutaminase 584764..586671 Spirochaeta smaragdinae DSM 11293 9488640 YP_003802300.1 CDS Spirs_0561 NC_014364.1 586703 587458 D COGs: COG1414 transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: aco:Amico_0085 IclR family transcriptional regulator; PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: IclR family transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator 586703..587458 Spirochaeta smaragdinae DSM 11293 9488641 YP_003802301.1 CDS Spirs_0562 NC_014364.1 587533 588333 D COGs: COG1414 transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: vvy:VV0550 transcriptional regulator; PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: transcriptional regulator; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator 587533..588333 Spirochaeta smaragdinae DSM 11293 9488642 YP_003802302.1 CDS Spirs_0563 NC_014364.1 588389 589774 D COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814:IPR017871:IPR001917; KEGG: hvo:HVO_B0257 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III; SPTR: Aminotransferase class-III; PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; 2,4-diaminobutyrate 4-transaminases; class III aminotransferase 588389..589774 Spirochaeta smaragdinae DSM 11293 9488643 YP_003802303.1 CDS Spirs_0564 NC_014364.1 589779 590804 D COGs: COG0136 aspartate-semialdehyde dehydrogenase; InterProIPR000534:IPR012280:IPR012080:IPR000319:IPR 005986; KEGG: dba:Dbac_1757 aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; PRIAM: aspartate-semialdehyde dehydrogenase; SPTR: aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms); aspartate-semialdehyde dehydrogenase 589779..590804 Spirochaeta smaragdinae DSM 11293 9488644 YP_003802304.1 CDS Spirs_0565 NC_014364.1 590819 591997 D COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR017439:IPR010168; KEGG: amt:Amet_1192 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase 590819..591997 Spirochaeta smaragdinae DSM 11293 9488645 YP_003802305.1 CDS Spirs_0566 NC_014364.1 592083 593156 D COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389; KEGG: amt:Amet_3729 TRAP dicarboxylate transporter-DctP subunit; PFAM: extracellular solute-binding protein, family 7; SPTR: TRAP dicarboxylate transporter-DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; extracellular solute-binding protein, family 7 592083..593156 Spirochaeta smaragdinae DSM 11293 9488646 YP_003802306.1 CDS Spirs_0567 NC_014364.1 593228 593815 D COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: amt:Amet_3728 tripartite ATP-independent periplasmic transporter DctQ; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: tripartite ATP-independent periplasmic transporter DctQ component; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ component 593228..593815 Spirochaeta smaragdinae DSM 11293 9488647 YP_003802307.1 CDS Spirs_0568 NC_014364.1 593836 595116 D COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR010656:IPR004681; KEGG: amt:Amet_3727 TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP dicarboxylate transporter DctM subunit; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM 593836..595116 Spirochaeta smaragdinae DSM 11293 9488648 YP_003802308.1 CDS Spirs_0569 NC_014364.1 595135 595866 D KEGG: nth:Nther_1851 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 595135..595866 Spirochaeta smaragdinae DSM 11293 9488649 YP_003802309.1 CDS Spirs_0570 NC_014364.1 595936 597108 D COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: gtn:GTNG_2272 Xaa-Pro aminopeptidase; PFAM: creatinase; peptidase M24; SPTR: Creatinase; PFAM: metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; creatinase 595936..597108 Spirochaeta smaragdinae DSM 11293 9488650 YP_003802310.1 CDS Spirs_0571 NC_014364.1 597133 598122 D COGs: COG1171 threonine dehydratase; InterPro IPR001926; KEGG: gtn:GTNG_2276 threonine dehydratase-like protein; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: threonine dehydratase-like protein; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: ectoine utilization protein EutB; pyridoxal-5'-phosphate-dependent protein subunit beta 597133..598122 Spirochaeta smaragdinae DSM 11293 9488651 YP_003802311.1 CDS Spirs_0572 NC_014364.1 598109 599113 D COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: gtn:GTNG_2271 ectoine utilization protein EutC; PFAM: ornithine cyclodeaminase/mu-crystallin; PRIAM: ornithine cyclodeaminase; SPTR: ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin family; TIGRFAM: ectoine utilization protein EutC; ornithine cyclodeaminase 598109..599113 Spirochaeta smaragdinae DSM 11293 9488652 YP_003802312.1 CDS Spirs_0573 NC_014364.1 599113 600303 D COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: gtn:GTNG_2272 Xaa-Pro aminopeptidase; PFAM: creatinase; peptidase M24; SPTR: Ectoine utilization protein EutD; PFAM: metallopeptidase family M24; Creatinase/Prolidase N-terminal domain; creatinase 599113..600303 Spirochaeta smaragdinae DSM 11293 9488653 YP_003802313.1 CDS Spirs_0574 NC_014364.1 600314 601618 D COGs: COG0527 Aspartokinase; InterPro IPR001048:IPR018042:IPR001341; KEGG: amt:Amet_3407 aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Aspartokinase; TIGRFAM: aspartate kinase; manually curated; PFAM: Amino acid kinase family; TIGRFAM: aspartate kinase; aspartate kinase 600314..601618 Spirochaeta smaragdinae DSM 11293 9488654 YP_003802314.1 CDS Spirs_0575 NC_014364.1 601668 602489 R COGs: COG3294 conserved hypothetical protein; KEGG: rmr:Rmar_1293 metal dependent phosphohydrolase; SPTR: uncharacterized protein; metal dependent phosphohydrolase complement(601668..602489) Spirochaeta smaragdinae DSM 11293 9488655 YP_003802315.1 CDS Spirs_0576 NC_014364.1 602539 603288 R InterPro IPR009875; KEGG: dpe:Dper_GL13628 GL13628 gene product from transcript GL13628-RA; PFAM: type IV pilus assembly PilZ; SPTR: GL13628; PFAM: PilZ domain; type IV pilus assembly PilZ complement(602539..603288) Spirochaeta smaragdinae DSM 11293 9488656 YP_003802316.1 CDS Spirs_0577 NC_014364.1 603285 603896 R COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; InterPro IPR005659; KEGG: vei:Veis_2173 chemoreceptor glutamine deamidase CheD; PFAM: CheD family protein; SPTR: CheD, stimulates methylation of MCP proteins; PFAM: CheD; stimulates methylation of MCP proteins; chemotaxis protein CheD complement(603285..603896) Spirochaeta smaragdinae DSM 11293 9488657 YP_003802317.1 CDS Spirs_0578 NC_014364.1 603908 605680 R KEGG: bbz:BbuZS7_0580 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(603908..605680) Spirochaeta smaragdinae DSM 11293 9488658 YP_003802318.1 CDS Spirs_0579 NC_014364.1 605780 606889 R COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR003593:IPR003439:IPR005116:IPR017871; KEGG: tma:TM1276 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain protein; SMART: ATPase AAA; SPTR: Multiple sugar-binding transport ATP-binding protein MsmK; PFAM: ABC transporter; TOBE domain; ABC transporter complement(605780..606889) Spirochaeta smaragdinae DSM 11293 9488659 YP_003802319.1 CDS Spirs_0580 NC_014364.1 606967 608274 R KEGG: tde:TDE2185 lipoprotein; SPTR: lipoprotein; lipoprotein complement(606967..608274) Spirochaeta smaragdinae DSM 11293 9488660 YP_003802320.1 CDS Spirs_0581 NC_014364.1 608312 609376 D COGs: COG1242 Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR005911; KEGG: dat:HRM2_32150 predicted Fe-S oxidoreductase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Predicted Fe-S oxidoreductase; TIGRFAM: conserved hypothetical protein; PFAM: radical SAM superfamily; TIGRFAM: radical SAM protein, TIGR01212 family; hypothetical protein 608312..609376 Spirochaeta smaragdinae DSM 11293 9488661 YP_003802321.1 CDS Spirs_0582 NC_014364.1 609373 610977 D KEGG: tde:TDE0063 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 609373..610977 Spirochaeta smaragdinae DSM 11293 9488662 YP_003802322.1 CDS Spirs_0583 NC_014364.1 611068 611604 R COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: sgr:SGR_1200 methylated-DNA--protein-cysteine S-methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: methylated-DNA--protein-cysteine S-methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; methylated-DNA/protein- cysteinemethyltransferase complement(611068..611604) Spirochaeta smaragdinae DSM 11293 9488663 YP_003802323.1 CDS Spirs_0584 NC_014364.1 611731 611880 D KEGG: mmx:MmarC6_0972 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 611731..611880 Spirochaeta smaragdinae DSM 11293 9488664 YP_003802324.1 CDS Spirs_0585 NC_014364.1 611963 612715 R InterPro IPR002790; KEGG: cph:Cpha266_2085 hypothetical protein; PFAM: protein of unknown function DUF88; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF88; hypothetical protein complement(611963..612715) Spirochaeta smaragdinae DSM 11293 9488665 YP_003802325.1 CDS Spirs_0586 NC_014364.1 612735 614879 R COGs: COG0116 N6-adenine-specific DNA methylase; InterPro IPR004114:IPR000241:IPR017244:IPR002052; KEGG: mca:MCA0712 23S rRNA m(2)G2445 methyltransferase; PFAM: RNA methylase; THUMP domain protein; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: ribosomal RNA large subunit methyltransferase L; PFAM: RNA methylase family UPF0020; S-adenosylmethionine-dependent methyltransferase; THUMP domain; rRNA (guanine-N(2)-)-methyltransferase complement(612735..614879) Spirochaeta smaragdinae DSM 11293 9488666 YP_003802326.1 CDS Spirs_0587 NC_014364.1 614921 615436 R COGs: COG2077 peroxiredoxin; InterPro IPR013740:IPR017936:IPR018219; KEGG: vpr:Vpar_0892 redoxin domain protein; PFAM: redoxin; SPTR: uncharacterized protein; PFAM: Redoxin; redoxin complement(614921..615436) Spirochaeta smaragdinae DSM 11293 9488667 YP_003802327.1 CDS Spirs_0588 NC_014364.1 615465 616850 R COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterProIPR013027:IPR000815:IPR004099:IPR012999:IPR 006258; KEGG: pla:Plav_3138 dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; SPTR: dihydrolipoyl dehydrogenase; TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; TIGRFAM: dihydrolipoamide dehydrogenase; dihydrolipoamide dehydrogenase complement(615465..616850) Spirochaeta smaragdinae DSM 11293 9488668 YP_003802328.1 CDS Spirs_0589 NC_014364.1 616884 618176 R COGs: COG0508 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide acyltransferase (E2) protein; InterPro IPR000089:IPR004167:IPR001078; KEGG: ote:Oter_2845 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; biotin/lipoyl attachment domain-containing protein; SPTR: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: 2-oxoacid dehydrogenases acyltransferase (catalytic domain); e3 binding domain; Biotin-requiring enzyme; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; hypothetical protein complement(616884..618176) Spirochaeta smaragdinae DSM 11293 9488669 YP_003802329.1 CDS Spirs_0590 NC_014364.1 618201 619181 R COGs: COG0022 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit beta; InterPro IPR005475:IPR005476; KEGG: hoh:Hoch_3707 transketolase; PFAM: transketolase; transketolase; SPTR: transketolase; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain; transketolase complement(618201..619181) Spirochaeta smaragdinae DSM 11293 9488670 YP_003802330.1 CDS Spirs_0591 NC_014364.1 619198 620154 R COGs: COG1071 pyruvate/2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type subunit alpha; InterPro IPR001017:IPR017597; KEGG: rmr:Rmar_1398 pyruvate dehydrogenase (acetyl-transferring) E1 component, subunit alpha; PFAM: dehydrogenase E1 component; PRIAM: pyruvate dehydrogenase (acetyl-transferring); SPTR: pyruvate dehydrogenase E1 component, subunit alpha; TIGRFAM: pyruvate dehydrogenase (acetyl-transferring) E1 component, subunit alpha; PFAM: dehydrogenase E1 component; TIGRFAM: pyruvate dehydrogenase E1 component, subunit alpha; pyruvate dehydrogenase E1 component subunit alpha complement(619198..620154) Spirochaeta smaragdinae DSM 11293 9488671 YP_003802331.1 CDS Spirs_0592 NC_014364.1 620164 620604 R InterPro IPR011576; KEGG: asa:ASA_1380 pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase-related FMN-binding; PFAM: pyridoxamine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein complement(620164..620604) Spirochaeta smaragdinae DSM 11293 9488672 YP_003802332.1 CDS Spirs_0593 NC_014364.1 620700 621098 R InterPro IPR001387; KEGG: rce:RC1_0656 DNA-binding protein, PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Riorf88 protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator complement(620700..621098) Spirochaeta smaragdinae DSM 11293 9488673 YP_003802333.1 CDS Spirs_0594 NC_014364.1 621572 622504 D COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR004338:IPR011303; KEGG: amt:Amet_3186 NQR2 and RnfD family protein; PFAM: NQR2 and RnfD family protein; SPTR: NQR2 and RnfD family protein; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; RnfABCDGE type electron transport complex subunit D 621572..622504 Spirochaeta smaragdinae DSM 11293 9488674 YP_003802334.1 CDS Spirs_0595 NC_014364.1 622501 623127 D COGs: COG2869 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrC; InterPro IPR007329; KEGG: pmo:Pmob_0063 FMN-binding domain-containing protein; PFAM: FMN-binding domain protein; SPTR: FMN-binding domain protein; PFAM: FMN-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; electron transport complex, RnfABCDGE type, G subunit; FMN-binding domain-containing protein 622501..623127 Spirochaeta smaragdinae DSM 11293 9488675 YP_003802335.1 CDS Spirs_0596 NC_014364.1 623129 623746 D COGs: COG1347 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrD; InterPro IPR003667:IPR011292; KEGG: amt:Amet_3188 RnfA-Nqr electron transport subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: RnfA-Nqr electron transport subunit; TIGRFAM: NADH:ubiquinone oxidoreductase, subunit D; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, D subunit; NADH:ubiquinone oxidoreductase subunit D 623129..623746 Spirochaeta smaragdinae DSM 11293 9488676 YP_003802336.1 CDS Spirs_0597 NC_014364.1 623743 624336 D COGs: COG2209 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrE; InterPro IPR003667; KEGG: amt:Amet_3189 RnfA-Nqr electron transport subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: RnfA-Nqr electron transport subunit; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit; electron transport complex, RnfABCDGE type, subunit alpha; RnfA-Nqr electron transport subunit 623743..624336 Spirochaeta smaragdinae DSM 11293 9488677 YP_003802337.1 CDS Spirs_0598 NC_014364.1 624346 625449 D COGs: COG2871 Na+-transporting NADH:ubiquinone oxidoreductase subunit NqrF; InterProIPR001221:IPR001041:IPR008333:IPR001433:IPR 017927; KEGG: pmo:Pmob_0066 oxidoreductase FAD/NAD(P)-binding subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; oxidoreductase FAD-binding domain protein; ferredoxin; SPTR: oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; oxidoreductase FAD-binding domain; oxidoreductase NAD-binding domain; TIGRFAM: NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit; oxidoreductase FAD/NAD(P)-binding domain-containing protein 624346..625449 Spirochaeta smaragdinae DSM 11293 9488678 YP_003802338.1 CDS Spirs_0599 NC_014364.1 625464 625952 D KEGG: pmo:Pmob_0067 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 625464..625952 Spirochaeta smaragdinae DSM 11293 9488679 YP_003802339.1 CDS Spirs_0600 NC_014364.1 626112 627101 D KEGG: rca:Rcas_1009 regulatory protein, DeoR; SPTR: Regulatory protein, DeoR; PFAM: IclR helix-turn-helix domain; regulatory protein, DeoR 626112..627101 Spirochaeta smaragdinae DSM 11293 9488680 YP_003802340.1 CDS Spirs_0601 NC_014364.1 627214 628014 D InterPro IPR014127; KEGG: emi:Emin_1510 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2400); TIGRFAM: conserved hypothetical protein TIGR02757; hypothetical protein 627214..628014 Spirochaeta smaragdinae DSM 11293 9488681 YP_003802341.1 CDS Spirs_0602 NC_014364.1 628042 628617 D COGs: COG1592 rubrerythrin; InterPro IPR003251:IPR004039:IPR009040; KEGG: drt:Dret_1205 rubrerythrin; PFAM: rubrerythrin; SPTR: rubrerythrin; PFAM: rubrerythrin; rubrerythrin 628042..628617 Spirochaeta smaragdinae DSM 11293 9488682 YP_003802342.1 CDS Spirs_0603 NC_014364.1 628672 629046 D COGs: COG2033 Desulfoferrodoxin; InterPro IPR004462:IPR002742:IPR004793; KEGG: dvl:Dvul_0204 desulfoferrodoxin; PFAM: Desulfoferrodoxin ferrous iron-binding region; Desulfoferrodoxin Dfx domain protein; SPTR: Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin; PFAM: Desulfoferrodoxin, N-terminal domain; Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain; desulfoferrodoxin 628672..629046 Spirochaeta smaragdinae DSM 11293 9488683 YP_003802343.1 CDS Spirs_0604 NC_014364.1 629067 629543 D COGs: COG1528 Ferritin-like protein; InterPro IPR008331:IPR009040; KEGG: cpo:COPRO5265_1102 nonheme iron-containing ferritin; PFAM: ferritin; SPTR: Nonheme iron-containing ferritin; PFAM: Ferritin-like domain; ferritin 629067..629543 Spirochaeta smaragdinae DSM 11293 9488684 YP_003802344.1 CDS Spirs_0605 NC_014364.1 629570 629731 D COGs: COG1773 Rubredoxin; InterPro IPR001052:IPR004039:IPR018527; KEGG: kol:Kole_2138 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; PFAM: Rubredoxin; Rubredoxin-type Fe(Cys)4 protein 629570..629731 Spirochaeta smaragdinae DSM 11293 9488685 YP_003802345.1 CDS Spirs_0607 NC_014364.1 630502 632958 R COGs: COG1509 lysine 2 3-aminomutase; InterPro IPR007197; KEGG: dat:HRM2_34920 lysine 2,3-aminomutase; PFAM: radical SAM domain protein; SPTR: lysine 2,3-aminomutase; PFAM: radical SAM superfamily; TIGRFAM: KamA family protein; radical SAM protein complement(630502..632958) Spirochaeta smaragdinae DSM 11293 9488687 YP_003802346.1 CDS Spirs_0608 NC_014364.1 633227 636697 R COGs: COG1410 methionine synthase I cobalamin-binding domain; InterProIPR003726:IPR000489:IPR003759:IPR006158:IPR 004223:IPR001412; KEGG: ddf:DEFDS_1683 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: homocysteine S-methyltransferase; dihydropteroate synthase DHPS; methionine synthase B12-binding module cap domain protein; cobalamin B12-binding domain protein; Vitamin B12 dependent methionine synthase activation region; SPTR: 5-methyltetrahydrofolate--homocysteine methyltransferase; PFAM: Pterin binding enzyme; Vitamin B12 dependent methionine synthase, activation domain; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: 5-methyltetrahydrofolate--homocysteine methyltransferase; methylmalonyl-CoA mutase C-terminal domain; homocysteine S-methyltransferase complement(633227..636697) Spirochaeta smaragdinae DSM 11293 9488688 YP_003802347.1 CDS Spirs_0609 NC_014364.1 636905 637120 D InterPro IPR001450:IPR017896:IPR017900; KEGG: ddf:DEFDS_0633 2-oxoacid oxidoreductase subunit delta; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 2-oxoacid oxidoreductase, delta subunit; PFAM: 4Fe-4S binding domain; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 636905..637120 Spirochaeta smaragdinae DSM 11293 9488689 YP_003802348.1 CDS Spirs_0610 NC_014364.1 637137 638189 D COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit alpha; InterPro IPR002880; KEGG: adg:Adeg_1385 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; SPTR: 2-oxoglutarate oxidoreductase subunit alpha; PFAM: domain; pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein 637137..638189 Spirochaeta smaragdinae DSM 11293 9488690 YP_003802349.1 CDS Spirs_0611 NC_014364.1 638179 638934 D COGs: COG1013 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit beta; InterPro IPR011766; KEGG: cbl:CLK_2865 2-oxoacid:acceptor oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: 2-oxoacid:acceptor oxidoreductase subunit beta; PFAM: thiamine pyrophosphate enzyme, C-terminal TPP binding domain; thiamine pyrophosphate protein TPP binding domain-containing protein 638179..638934 Spirochaeta smaragdinae DSM 11293 9488691 YP_003802350.1 CDS Spirs_0612 NC_014364.1 638946 639479 D COGs: COG1014 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit gamma; InterPro IPR019752; KEGG: hor:Hore_06800 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin), subunit gamma; PFAM: pyruvate/ketoisovalerate oxidoreductase; SPTR: pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit gamma-like protein; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate/ketoisovalerate oxidoreductase 638946..639479 Spirochaeta smaragdinae DSM 11293 9488692 YP_003802351.1 CDS Spirs_0613 NC_014364.1 639581 640117 D COGs: COG2335 Secreted and surface protein containing fasciclin-like repeats; InterPro IPR000782; KEGG: ddr:Deide_15070 fasciclin domain protein, precursor; PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; SPTR: beta-Ig-H3/Fasciclin; PFAM: Fasciclin domain; beta-Ig-H3/fasciclin 639581..640117 Spirochaeta smaragdinae DSM 11293 9488693 YP_003802352.1 CDS Spirs_0614 NC_014364.1 640130 640876 R KEGG: spu:756242 hypothetical protein LOC756242; SPTR: phosphodiesterase; hypothetical protein complement(640130..640876) Spirochaeta smaragdinae DSM 11293 9488694 YP_003802353.1 CDS Spirs_0616 NC_014364.1 641066 642886 D COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439:IPR017871; KEGG: glo:Glov_3511 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 641066..642886 Spirochaeta smaragdinae DSM 11293 9488696 YP_003802354.1 CDS Spirs_0617 NC_014364.1 642936 643280 D KEGG: ecb:100068727 microtubule-actin crosslinking factor 1; SPTR: cell wall surface anchor family protein; hypothetical protein 642936..643280 Spirochaeta smaragdinae DSM 11293 9488697 YP_003802355.1 CDS Spirs_0618 NC_014364.1 643435 644049 R KEGG: lel:LELG_03568 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(643435..644049) Spirochaeta smaragdinae DSM 11293 9488698 YP_003802356.1 CDS Spirs_0619 NC_014364.1 644292 645410 R KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein complement(644292..645410) Spirochaeta smaragdinae DSM 11293 9488699 YP_003802357.1 CDS Spirs_0620 NC_014364.1 645571 649131 R COGs: COG0674 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR002880:IPR019752:IPR019456:IPR001450:IPR 011766:IPR017900:IPR017896:IPR011895; KEGG: tde:TDE0665 pyruvate ferredoxin/flavodoxin oxidoreductase family protein; PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; pyruvate/ketoisovalerate oxidoreductase; pyruvate-flavodoxin oxidoreductase, EKR domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: pyruvate ferredoxin/flavodoxin oxidoreductase family protein; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; PFAM: Domain of unknown function; domain; pyruvate ferredoxin/flavodoxin oxidoreductase; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; pyruvate ferredoxin/flavodoxin oxidoreductase complement(645571..649131) Spirochaeta smaragdinae DSM 11293 9488700 YP_003802358.1 CDS Spirs_0621 NC_014364.1 649257 650807 R KEGG: pmo:Pmob_1143 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(649257..650807) Spirochaeta smaragdinae DSM 11293 9488701 YP_003802359.1 CDS Spirs_0622 NC_014364.1 650877 652361 R COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: csc:Csac_2551 integral membrane sensor signal transduction histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; histidine kinase complement(650877..652361) Spirochaeta smaragdinae DSM 11293 9488702 YP_003802360.1 CDS Spirs_0623 NC_014364.1 652378 652905 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060; KEGG: bsu:BSU06960 two-component response regulator [YesM]; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Uncharacterized transcriptional regulatory protein yesN; PFAM: Response regulator receiver domain; response regulator receiver protein complement(652378..652905) Spirochaeta smaragdinae DSM 11293 9488703 YP_003802361.1 CDS Spirs_0624 NC_014364.1 652918 653607 R COGs: COG1234 metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: csc:Csac_2383 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(652918..653607) Spirochaeta smaragdinae DSM 11293 9488704 YP_003802362.1 CDS Spirs_0625 NC_014364.1 653616 654425 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bbe:BBR47_57310 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(653616..654425) Spirochaeta smaragdinae DSM 11293 9488705 YP_003802363.1 CDS Spirs_0626 NC_014364.1 654439 655401 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: bbe:BBR47_57320 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: glycerol-3-phosphat transporter; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(654439..655401) Spirochaeta smaragdinae DSM 11293 9488706 YP_003802364.1 CDS Spirs_0627 NC_014364.1 655437 656786 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: bbe:BBR47_57330 probable glycerol-3-phosphate ABC transporter substrate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(655437..656786) Spirochaeta smaragdinae DSM 11293 9488707 YP_003802365.1 CDS Spirs_0628 NC_014364.1 656989 657606 R InterPro IPR003779; KEGG: mbu:Mbur_0404 alkylhydroperoxidase-like protein; PFAM: carboxymuconolactone decarboxylase; SPTR: carboxymuconolactone decarboxylase family protein; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain; carboxymuconolactone decarboxylase complement(656989..657606) Spirochaeta smaragdinae DSM 11293 9488708 YP_003802366.1 CDS Spirs_0629 NC_014364.1 658095 658574 D InterPro IPR000182; KEGG: dhd:Dhaf_3246 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; manually curated; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 658095..658574 Spirochaeta smaragdinae DSM 11293 9488709 YP_003802367.1 CDS Spirs_0630 NC_014364.1 658621 659358 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: eat:EAT1b_2257 phophonate C-P lyase system transcriptional regulator PhnF, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Phophonate C-P lyase system transcriptional regulator PhnF, GntR family; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(658621..659358) Spirochaeta smaragdinae DSM 11293 9488710 YP_003802368.1 CDS Spirs_0631 NC_014364.1 659487 661214 D COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR004843:IPR018282:IPR006179; KEGG: syp:SYNPCC7002_A0150 Ser/Thr protein phosphatase family protein; PFAM: metallophosphoesterase; SPTR: Ser/Thr protein phosphatase family protein; PFAM: 5'-nucleotidase, C-terminal domain; metallophosphoesterase 659487..661214 Spirochaeta smaragdinae DSM 11293 9488711 YP_003802369.1 CDS Spirs_0632 NC_014364.1 661245 662066 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_20610 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(661245..662066) Spirochaeta smaragdinae DSM 11293 9488712 YP_003802370.1 CDS Spirs_0633 NC_014364.1 662081 662950 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: cju:C8J_1586 hypothetical protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(662081..662950) Spirochaeta smaragdinae DSM 11293 9488713 YP_003802371.1 CDS Spirs_0634 NC_014364.1 663036 664349 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: bcl:ABC0337 glycerol-3-phosphate ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(663036..664349) Spirochaeta smaragdinae DSM 11293 9488714 YP_003802372.1 CDS Spirs_0635 NC_014364.1 664640 666382 D COGs: COG0366 glycosidase; InterPro IPR006047:IPR006589:IPR016377; KEGG: str:Sterm_1523 alpha amylase catalytic region; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: sucrose phosphorylase; PFAM: alpha amylase, catalytic domain; alpha amylase catalytic subunit 664640..666382 Spirochaeta smaragdinae DSM 11293 9488715 YP_003802373.1 CDS Spirs_0636 NC_014364.1 666401 667699 R InterPro IPR001296; KEGG: dol:Dole_2515 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase complement(666401..667699) Spirochaeta smaragdinae DSM 11293 9488716 YP_003802374.1 CDS Spirs_0637 NC_014364.1 667841 668428 D InterPro IPR000086:IPR020084:IPR001455:IPR020476; KEGG: tde:TDE0010 MutT/NUDIX family protein; PFAM: NUDIX hydrolase; SPTR: MutT/nudix family protein; PFAM: NUDIX domain; NUDIX hydrolase 667841..668428 Spirochaeta smaragdinae DSM 11293 9488717 YP_003802375.1 CDS Spirs_0638 NC_014364.1 668530 668742 D InterPro IPR019239; KEGG: tit:Thit_2161 protein of unknown function DUF2191; PFAM: protein of unknown function DUF2191; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2191); hypothetical protein 668530..668742 Spirochaeta smaragdinae DSM 11293 9488718 YP_003802376.1 CDS Spirs_0639 NC_014364.1 668729 669136 D InterPro IPR002716; KEGG: tit:Thit_2162 twitching motility protein PilT; PFAM: twitching motility protein PilT; SPTR: twitching motility protein PilT; PFAM: PIN domain; twitching motility protein PilT 668729..669136 Spirochaeta smaragdinae DSM 11293 9488719 YP_003802377.1 CDS Spirs_0640 NC_014364.1 669143 669853 R KEGG: tye:THEYE_A1891 hypothetical protein; SPTR: uncharacterized protein; PFAM: FecR protein; hypothetical protein complement(669143..669853) Spirochaeta smaragdinae DSM 11293 9488720 YP_003802378.1 CDS Spirs_0641 NC_014364.1 669919 670809 R COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: smd:Smed_2069 LysR family transcriptional regulator; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator complement(669919..670809) Spirochaeta smaragdinae DSM 11293 9488721 YP_003802379.1 CDS Spirs_0642 NC_014364.1 670917 672455 D COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: smd:Smed_2068 sulfatase; PFAM: sulfatase; SPTR: sulfatase; PFAM: Sulfatase; sulfatase 670917..672455 Spirochaeta smaragdinae DSM 11293 9488722 YP_003802380.1 CDS Spirs_0643 NC_014364.1 672487 673458 D COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: pmu:PM1679 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein 672487..673458 Spirochaeta smaragdinae DSM 11293 9488723 YP_003802381.1 CDS Spirs_0644 NC_014364.1 673532 673984 D KEGG: pmu:PM1680 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 673532..673984 Spirochaeta smaragdinae DSM 11293 9488724 YP_003802382.1 CDS Spirs_0645 NC_014364.1 673997 675496 D COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: pmu:PM1681 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein 673997..675496 Spirochaeta smaragdinae DSM 11293 9488725 YP_003802383.1 CDS Spirs_0646 NC_014364.1 675499 676683 D COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197:IPR000385; KEGG: vvu:VV2_1107 arylsulfatase regulator; PFAM: radical SAM protein; SPTR: Arylsulfatase regulator; PFAM: radical SAM superfamily; radical SAM protein 675499..676683 Spirochaeta smaragdinae DSM 11293 9488726 YP_003802384.1 CDS Spirs_0647 NC_014364.1 676703 676993 D InterPro IPR003807; KEGG: cno:NT01CX_0294 hypothetical protein; PFAM: protein of unknown function DUF202; SPTR: Predicted protein; PFAM: Domain of unknown function DUF; hypothetical protein 676703..676993 Spirochaeta smaragdinae DSM 11293 9488727 YP_003802385.1 CDS Spirs_0649 NC_014364.1 677618 679240 R KEGG: rno:687494 hypothetical protein LOC687494; SPTR: ORF449; hypothetical protein complement(677618..679240) Spirochaeta smaragdinae DSM 11293 9488729 YP_003802386.1 CDS Spirs_0651 NC_014364.1 679940 680680 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: rpc:RPC_1874 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 679940..680680 Spirochaeta smaragdinae DSM 11293 9488731 YP_003802387.1 CDS Spirs_0652 NC_014364.1 680694 682847 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR004358:IPR 005467; KEGG: gbm:Gbem_0800 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; integral membrane sensor hybrid histidine kinase 680694..682847 Spirochaeta smaragdinae DSM 11293 9488732 YP_003802388.1 CDS Spirs_0653 NC_014364.1 682901 683515 R COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: pfl:PFL_2297 RhtB family transporter; PFAM: lysine exporter protein (LYSE/YGGA); SPTR: lysine exporter (LYSE/YGGA); PFAM: LysE type translocator; lysine exporter LysE/YggA complement(682901..683515) Spirochaeta smaragdinae DSM 11293 9488733 YP_003802389.1 CDS Spirs_0655 NC_014364.1 683682 683990 R KEGG: lbl:LBL_2456 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(683682..683990) Spirochaeta smaragdinae DSM 11293 9488735 YP_003802390.1 CDS Spirs_0656 NC_014364.1 684091 684297 R KEGG: lbf:LBF_2184 VagC-related protein; SPTR: virulence-associated protein B; manually curated; VagC-like protein complement(684091..684297) Spirochaeta smaragdinae DSM 11293 9488736 YP_003802391.1 CDS Spirs_0657 NC_014364.1 684519 685166 D InterPro IPR001647; KEGG: dhd:Dhaf_4031 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 684519..685166 Spirochaeta smaragdinae DSM 11293 9488737 YP_003802392.1 CDS Spirs_0658 NC_014364.1 685432 686634 D COGs: COG1262 conserved hypothetical protein; InterPro IPR005532; KEGG: tde:TDE2269 hypothetical protein; PFAM: protein of unknown function DUF323; SPTR: transcriptional regulator; PFAM: Formylglycine-generating sulfatase enzyme; hypothetical protein 685432..686634 Spirochaeta smaragdinae DSM 11293 9488738 YP_003802393.1 CDS Spirs_0659 NC_014364.1 686921 687466 R COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: cac:CAC0723 AcrR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, AcrR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(686921..687466) Spirochaeta smaragdinae DSM 11293 9488739 YP_003802394.1 CDS Spirs_0660 NC_014364.1 687595 688521 D COGs: COG2267 lysophospholipase; KEGG: lbf:LBF_3037 lysophospholipase; SPTR: uncharacterized protein; lysophospholipase 687595..688521 Spirochaeta smaragdinae DSM 11293 9488740 YP_003802395.1 CDS Spirs_0661 NC_014364.1 688618 689364 D COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: cdl:CDR20291_1480 hypothetical protein; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 688618..689364 Spirochaeta smaragdinae DSM 11293 9488741 YP_003802396.1 CDS Spirs_0662 NC_014364.1 689411 689842 R InterPro IPR000182; KEGG: bla:BLA_1389 acetyltransferase, GNAT family; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase complement(689411..689842) Spirochaeta smaragdinae DSM 11293 9488742 YP_003802397.1 CDS Spirs_0663 NC_014364.1 689949 690398 R InterPro IPR004360:IPR018146; KEGG: dma:DMR_33680 hypothetical protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: uncharacterized protein; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; glyoxalase/bleomycin resistance protein/dioxygenase complement(689949..690398) Spirochaeta smaragdinae DSM 11293 9488743 YP_003802398.1 CDS Spirs_0664 NC_014364.1 690541 692427 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090:IPR003660; KEGG: baf:BAPKO_0628 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis protein; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(690541..692427) Spirochaeta smaragdinae DSM 11293 9488744 YP_003802399.1 CDS Spirs_0665 NC_014364.1 692547 693155 D COGs: COG0605 superoxide dismutase; InterPro IPR019831:IPR019832:IPR019833:IPR001189; KEGG: bsu:BSU25020 superoxide dismutase; PFAM: Manganese/iron superoxide dismutase-like; SPTR: superoxide dismutase; PFAM: Iron/manganese superoxide dismutases, alpha-hairpin domain; Iron/manganese superoxide dismutases, C-terminal domain; Manganese/iron superoxide dismutase 692547..693155 Spirochaeta smaragdinae DSM 11293 9488745 YP_003802400.1 CDS Spirs_0666 NC_014364.1 693755 694912 D COGs: COG0562 UDP-galactopyranose mutase; InterPro IPR013027:IPR015899:IPR004379; KEGG: mth:MTH344 UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase-like; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: UDP-galactopyranose mutase; SPTR: UDP-galactopyranose mutase; TIGRFAM: UDP-galactopyranose mutase; PFAM: UDP-galactopyranose mutase; FAD binding domain; TIGRFAM: UDP-galactopyranose mutase; UDP-galactopyranose mutase 693755..694912 Spirochaeta smaragdinae DSM 11293 9488746 YP_003802401.1 CDS Spirs_0667 NC_014364.1 694933 695721 D COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease; InterPro IPR013525; KEGG: oih:OB2924 teichoic acid ABC transporter permease; PFAM: ABC transporter; SPTR: ABC-type polysaccharide/polyol phosphate export systems, permease component; PFAM: ABC transporter; ABC transporter 694933..695721 Spirochaeta smaragdinae DSM 11293 9488747 YP_003802402.1 CDS Spirs_0668 NC_014364.1 695723 696469 D COGs: COG1134 ABC-type polysaccharide/polyol phosphate transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: ABC transporter; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC-type polysaccharide/polyol phosphate transporter, ATPase component; PFAM: ABC transporter; ABC transporter 695723..696469 Spirochaeta smaragdinae DSM 11293 9488748 YP_003802403.1 CDS Spirs_0669 NC_014364.1 696494 699796 D COGs: COG3754 Lipopolysaccharide biosynthesis protein; InterPro IPR007739:IPR001173; KEGG: rsk:RSKD131_4489 hypothetical protein; PFAM: glycosyl transferase family 2; Rhamnan synthesis F; SPTR: uncharacterized protein; PFAM: Rhamnan synthesis protein F; glycosyl transferase family 2; family 2 glycosyl transferase 696494..699796 Spirochaeta smaragdinae DSM 11293 9488749 YP_003802404.1 CDS Spirs_0670 NC_014364.1 699818 705244 D COGs: COG3754 Lipopolysaccharide biosynthesis protein; InterPro IPR007739; KEGG: afo:Afer_1971 glycosyl transferase family 2; PFAM: Rhamnan synthesis F; SPTR: glycosyl transferase family 2; PFAM: Rhamnan synthesis protein F; phosphoribosyl transferase domain; protein of unknown function (DUF616); Rhamnan synthesis F 699818..705244 Spirochaeta smaragdinae DSM 11293 9488750 YP_003802405.1 CDS Spirs_0671 NC_014364.1 705617 705847 D KEGG: dat:HRM2_44590 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 705617..705847 Spirochaeta smaragdinae DSM 11293 9488751 YP_003802406.1 CDS Spirs_0672 NC_014364.1 705920 707116 D COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: bhy:BHWA1_01693 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; SPTR: UDP-glucose/GDP-mannose dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; nucleotide sugar dehydrogenase 705920..707116 Spirochaeta smaragdinae DSM 11293 9488752 YP_003802407.1 CDS Spirs_0673 NC_014364.1 707116 708135 D COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bhy:BHWA1_01692 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 707116..708135 Spirochaeta smaragdinae DSM 11293 9488753 YP_003802408.1 CDS Spirs_0674 NC_014364.1 708148 708873 D InterPro IPR001173; KEGG: bhy:BHWA1_01691 glycosyl transferase, family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase, family 2; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 708148..708873 Spirochaeta smaragdinae DSM 11293 9488754 YP_003802409.1 CDS Spirs_0675 NC_014364.1 708870 709229 D InterPro IPR000620; KEGG: tle:Tlet_1278 small multidrug resistance protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Small multidrug resistance protein; PFAM: EamA-like transporter family; hypothetical protein 708870..709229 Spirochaeta smaragdinae DSM 11293 9488755 YP_003802410.1 CDS Spirs_0676 NC_014364.1 709266 712436 D InterPro IPR005479; KEGG: lpp:lpp0676 hypothetical protein; SPTR: transmembrane protein; hypothetical protein 709266..712436 Spirochaeta smaragdinae DSM 11293 9488756 YP_003802411.1 CDS Spirs_0677 NC_014364.1 712819 713241 D InterPro IPR007197; KEGG: sfu:Sfum_0802 radical SAM domain-containing protein; PFAM: radical SAM protein; SPTR: radical SAM domain protein; PFAM: radical SAM superfamily; radical SAM protein 712819..713241 Spirochaeta smaragdinae DSM 11293 9488757 YP_003802412.1 CDS Spirs_0678 NC_014364.1 713264 714202 D KEGG: tet:TTHERM_01006580 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 713264..714202 Spirochaeta smaragdinae DSM 11293 9488758 YP_003802413.1 CDS Spirs_0679 NC_014364.1 714293 715171 D COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005907; KEGG: sbc:SbBS512_E1194 glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; SPTR: glucose-1-phosphate thymidylyltransferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form; glucose-1-phosphate thymidylyltransferase 714293..715171 Spirochaeta smaragdinae DSM 11293 9488759 YP_003802414.1 CDS Spirs_0680 NC_014364.1 715161 715703 D COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: ton:TON_1848 hypothetical dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: Hypothetical dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose 3,5-epimerase 715161..715703 Spirochaeta smaragdinae DSM 11293 9488760 YP_003802415.1 CDS Spirs_0681 NC_014364.1 715700 716578 D COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: bhy:BHWA1_02693 dTDP-4-keto-L-rhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase 715700..716578 Spirochaeta smaragdinae DSM 11293 9488761 YP_003802416.1 CDS Spirs_0682 NC_014364.1 716575 717645 D COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: dap:Dacet_2762 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase; dTDP-glucose 4,6-dehydratase 716575..717645 Spirochaeta smaragdinae DSM 11293 9488762 YP_003802417.1 CDS Spirs_0683 NC_014364.1 717615 718676 D COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: cyt:cce_2363 glycosyl transferase; PFAM: glycosyl transferase family 2; SPTR: uncharacterized protein; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 717615..718676 Spirochaeta smaragdinae DSM 11293 9488763 YP_003802418.1 CDS Spirs_0684 NC_014364.1 718677 720170 D COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: sme:SM_b21311 glycosyltransferase, forming alpha-gylcosyl linkages protein; PFAM: glycosyl transferase group 1; SPTR: glycosyltransferase, forming alpha glycosyl linkages protein; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase 718677..720170 Spirochaeta smaragdinae DSM 11293 9488764 YP_003802419.1 CDS Spirs_0685 NC_014364.1 720179 721231 D COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: mst:Msp_0212 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Predicted glycosyltransferase; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 720179..721231 Spirochaeta smaragdinae DSM 11293 9488765 YP_003802420.1 CDS Spirs_0686 NC_014364.1 721249 722301 D COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: mst:Msp_0212 glycosyltransferase; PFAM: glycosyl transferase family 2; SPTR: Predicted glycosyltransferase; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 721249..722301 Spirochaeta smaragdinae DSM 11293 9488766 YP_003802421.1 CDS Spirs_0687 NC_014364.1 722467 722709 R COGs: COG4675 Microcystin-dependent protein; InterPro IPR011083; KEGG: pna:Pnap_4767 phage tail collar domain-containing protein; PFAM: Tail Collar domain protein; SPTR: Phage Tail Collar domain protein; PFAM: Phage Tail Collar Domain; hypothetical protein complement(722467..722709) Spirochaeta smaragdinae DSM 11293 9488767 YP_003802422.1 CDS Spirs_0688 NC_014364.1 723050 724726 D InterPro IPR001480:IPR000909; KEGG: spe:Spro_2388 membrane attack complex component/perforin/complement C9; PFAM: Curculin domain protein (mannose-binding) lectin; SMART: phosphatidylinositol-specific phospholipase C X region; SPTR: membrane attack complex component/perforin/complement C9; PFAM: phosphatidylinositol-specific phospholipase C, X domain; Curculin domain-containing protein (mannose-binding) lectin 723050..724726 Spirochaeta smaragdinae DSM 11293 9488768 YP_003802423.1 CDS Spirs_0689 NC_014364.1 724712 725761 R InterPro IPR001584; KEGG: dap:Dacet_2583 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; manually curated; PFAM: Integrase core domain; Integrase catalytic subunit complement(724712..725761) Spirochaeta smaragdinae DSM 11293 9488769 YP_003802424.1 CDS Spirs_0691 NC_014364.1 726326 726994 D InterPro IPR000772; KEGG: fjo:Fjoh_4174 carbohydrate-binding family 6 protein; PFAM: ricin B lectin; SMART: ricin B lectin; SPTR: uncharacterized protein; PFAM: ricin-type beta-trefoil lectin domain; ricin B lectin 726326..726994 Spirochaeta smaragdinae DSM 11293 9488771 YP_003802425.1 CDS Spirs_0692 NC_014364.1 727108 727332 R KEGG: pph:Ppha_2188 prevent-host-death family protein; SPTR: Prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(727108..727332) Spirochaeta smaragdinae DSM 11293 9488772 YP_003802426.1 CDS Spirs_0693 NC_014364.1 727333 727725 R InterPro IPR002716; KEGG: paa:Paes_1738 twitching motility protein PilT; PFAM: twitching motility protein PilT; SPTR: uncharacterized protein; PFAM: PIN domain; twitching motility protein PilT complement(727333..727725) Spirochaeta smaragdinae DSM 11293 9488773 YP_003802427.1 CDS Spirs_0696 NC_014364.1 728309 728587 R InterPro IPR006442; KEGG: gur:Gura_0630 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(728309..728587) Spirochaeta smaragdinae DSM 11293 9488776 YP_003802428.1 CDS Spirs_0698 NC_014364.1 728890 729198 D InterPro IPR002934; KEGG: mja:MJ1379 hypothetical protein; PFAM: DNA polymerase beta domain protein region; SPTR: Uncharacterized protein MJ1379; PFAM: nucleotidyltransferase domain; DNA polymerase beta domain-containing protein region 728890..729198 Spirochaeta smaragdinae DSM 11293 9488778 YP_003802429.1 CDS Spirs_0699 NC_014364.1 729373 729615 D KEGG: hor:Hore_00320 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 729373..729615 Spirochaeta smaragdinae DSM 11293 9488779 YP_003802430.1 CDS Spirs_0701 NC_014364.1 730021 730443 R KEGG: lbf:LBF_2813 PIN domain protein; SPTR: PIN domain protein; PIN domain-containing protein complement(730021..730443) Spirochaeta smaragdinae DSM 11293 9488781 YP_003802431.1 CDS Spirs_0702 NC_014364.1 730622 730951 R COGs: COG2337 Growth inhibitor; InterPro IPR003477; KEGG: tde:TDE2247 PemK family protein; PFAM: PemK family protein; SPTR: PemK family protein; PFAM: PemK-like protein; MazF family transcriptional regulator complement(730622..730951) Spirochaeta smaragdinae DSM 11293 9488782 YP_003802432.1 CDS Spirs_0703 NC_014364.1 730939 731187 R InterPro IPR007159; KEGG: lbf:LBF_0717 proteic killer gene system protein , suppressor of inhibitory function of MazF; PFAM: SpoVT/AbrB domain protein; SPTR: PemI family protein; PFAM: SpoVT / AbrB like domain; MazE family transcriptional regulator complement(730939..731187) Spirochaeta smaragdinae DSM 11293 9488783 YP_003802433.1 CDS Spirs_0704 NC_014364.1 731245 732255 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tte:TTE1952 transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: HTH-type transcriptional repressor cytR; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(731245..732255) Spirochaeta smaragdinae DSM 11293 9488784 YP_003802434.1 CDS Spirs_0705 NC_014364.1 732490 733497 D COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: str:Sterm_1486 periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; periplasmic binding protein/LacI transcriptional regulator 732490..733497 Spirochaeta smaragdinae DSM 11293 9488785 YP_003802435.1 CDS Spirs_0706 NC_014364.1 733586 735088 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: amt:Amet_0457 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter 733586..735088 Spirochaeta smaragdinae DSM 11293 9488786 YP_003802436.1 CDS Spirs_0707 NC_014364.1 735085 736062 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: str:Sterm_1488 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 735085..736062 Spirochaeta smaragdinae DSM 11293 9488787 YP_003802437.1 CDS Spirs_0708 NC_014364.1 736073 737146 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: ote:Oter_1780 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase family, NAD-binding Rossmann fold protein; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 736073..737146 Spirochaeta smaragdinae DSM 11293 9488788 YP_003802438.1 CDS Spirs_0709 NC_014364.1 737159 738148 D COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307:IPR011418; KEGG: psl:Psta_1535 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain protein TIM barrel; AP endonuclease 2 domain protein; SPTR: uncharacterized protein; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel; xylose isomerase 737159..738148 Spirochaeta smaragdinae DSM 11293 9488789 YP_003802439.1 CDS Spirs_0710 NC_014364.1 738500 739552 D COGs: COG3274 conserved hypothetical protein; KEGG: ere:EUBREC_2644 hypothetical protein; SPTR: Uncharacterized protein conserved in bacteria; PFAM: acyltransferase family; hypothetical protein 738500..739552 Spirochaeta smaragdinae DSM 11293 9488790 YP_003802440.1 CDS Spirs_0711 NC_014364.1 739549 740586 D COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: msi:Msm_1594 glycosyltransferase/CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; PFAM: glycosyl transferase family 2; SPTR:glycosyltransferase/CDP- glycerol:poly(glycerophosphate) glycerophosphotransferase, GT2 family; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 739549..740586 Spirochaeta smaragdinae DSM 11293 9488791 YP_003802441.1 CDS Spirs_0712 NC_014364.1 740595 741875 D KEGG: jan:Jann_2132 TonB-dependent haem/haemoglobin receptor; SPTR: uncharacterized protein; hypothetical protein 740595..741875 Spirochaeta smaragdinae DSM 11293 9488792 YP_003802442.1 CDS Spirs_0713 NC_014364.1 741875 742639 D COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: bha:BH3661 teichuronic acid biosynthesis; PFAM: glycosyl transferase family 2; SPTR: Teichuronic acid biosynthesis; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 741875..742639 Spirochaeta smaragdinae DSM 11293 9488793 YP_003802443.1 CDS Spirs_0714 NC_014364.1 742636 743328 D COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: ank:AnaeK_4048 ABC transporter-related protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 742636..743328 Spirochaeta smaragdinae DSM 11293 9488794 YP_003802444.1 CDS Spirs_0715 NC_014364.1 743332 744777 D COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838:IPR005829; KEGG: tde:TDE1851 ABC transporter permease, PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease, ; PFAM: Predicted permease; hypothetical protein 743332..744777 Spirochaeta smaragdinae DSM 11293 9488795 YP_003802445.1 CDS Spirs_0716 NC_014364.1 744779 746086 D COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838; KEGG: tde:TDE1850 ABC transporter permease, PFAM: protein of unknown function DUF214; SPTR: ABC transporter permease; PFAM: Predicted permease; hypothetical protein 744779..746086 Spirochaeta smaragdinae DSM 11293 9488796 YP_003802446.1 CDS Spirs_0717 NC_014364.1 746086 746862 D KEGG: tde:TDE1849 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 746086..746862 Spirochaeta smaragdinae DSM 11293 9488797 YP_003802447.1 CDS Spirs_0718 NC_014364.1 747259 748146 D COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: sme:SMa0520 transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: RpiR family transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator 747259..748146 Spirochaeta smaragdinae DSM 11293 9488798 YP_003802448.1 CDS Spirs_0719 NC_014364.1 748139 749440 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: bbe:BBR47_57330 probable glycerol-3-phosphate ABC transporter substrate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Probable glycerol-3-phosphate ABC transporter substrate binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 748139..749440 Spirochaeta smaragdinae DSM 11293 9488799 YP_003802449.1 CDS Spirs_0720 NC_014364.1 749519 750400 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: bbe:BBR47_57320 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 749519..750400 Spirochaeta smaragdinae DSM 11293 9488800 YP_003802450.1 CDS Spirs_0721 NC_014364.1 750393 751265 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: mno:Mnod_6752 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 750393..751265 Spirochaeta smaragdinae DSM 11293 9488801 YP_003802451.1 CDS Spirs_0722 NC_014364.1 751262 751768 D KEGG: cth:Cthe_1150 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 751262..751768 Spirochaeta smaragdinae DSM 11293 9488802 YP_003802452.1 CDS Spirs_0723 NC_014364.1 751752 752477 D InterPro IPR005834; KEGG: scl:sce8177 hypothetical protein; PFAM: haloacid dehalogenase; SPTR: uncharacterized protein; PFAM: haloacid dehalogenase-like hydrolase; haloacid dehalogenase 751752..752477 Spirochaeta smaragdinae DSM 11293 9488803 YP_003802453.1 CDS Spirs_0724 NC_014364.1 752573 753718 D KEGG: gvi:gll2718 hypothetical protein; SPTR: Gll2718 protein; PFAM: acyltransferase family; hypothetical protein 752573..753718 Spirochaeta smaragdinae DSM 11293 9488804 YP_003802454.1 CDS Spirs_0725 NC_014364.1 753744 754352 D COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dal:Dalk_0171 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator 753744..754352 Spirochaeta smaragdinae DSM 11293 9488805 YP_003802455.1 CDS Spirs_0726 NC_014364.1 754472 755806 D InterPro IPR011579:IPR004256; KEGG: bfs:BF1799 ATP/GTP-binding protein; PFAM: ATPase; DUF234 DEXX-box ATPase; SPTR: Predicted protein; PFAM: Archaeal ATPase; Archaea bacterial proteins of unknown function; ATPase 754472..755806 Spirochaeta smaragdinae DSM 11293 9488806 YP_003802456.1 CDS Spirs_0727 NC_014364.1 755883 756614 R KEGG: app:CAP2UW1_3991 periplasmic solute binding protein; SPTR: Periplasmic solute binding protein; PFAM: Periplasmic solute binding protein family; periplasmic solute binding protein complement(755883..756614) Spirochaeta smaragdinae DSM 11293 9488807 YP_003802457.1 CDS Spirs_0728 NC_014364.1 756607 757410 R COGs: COG1108 ABC-type Mn2+/Zn2+ transporters permeases; InterPro IPR001626; KEGG: sro:Sros_3482 zinc ABC transporter permease; PFAM: ABC transporter; SPTR: uncharacterized protein; PFAM: ABC 3 transport family; ABC transporter complement(756607..757410) Spirochaeta smaragdinae DSM 11293 9488808 YP_003802458.1 CDS Spirs_0729 NC_014364.1 757404 758423 R COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR015067:IPR003439:IPR017871:IPR003593; KEGG: fsu:Fisuc_0551 ABC transporter related protein; PFAM: ABC transporter; Domain of unknown function DUF1893; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; Domain of unknown function (DUF1893); ABC transporter complement(757404..758423) Spirochaeta smaragdinae DSM 11293 9488809 YP_003802459.1 CDS Spirs_0730 NC_014364.1 758420 759385 R KEGG: tde:TDE2612 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(758420..759385) Spirochaeta smaragdinae DSM 11293 9488810 YP_003802460.1 CDS Spirs_0731 NC_014364.1 759451 760659 R COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: bvu:BVU_4118 renin-binding protein-related protein; PFAM: N-acylglucosamine 2-epimerase; PRIAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase complement(759451..760659) Spirochaeta smaragdinae DSM 11293 9488811 YP_003802461.1 CDS Spirs_0732 NC_014364.1 760800 762152 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gyc:GYMC61_2959 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 760800..762152 Spirochaeta smaragdinae DSM 11293 9488812 YP_003802462.1 CDS Spirs_0733 NC_014364.1 762221 763081 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: rle:RL2748 transmembrane component of ABC transporter; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter permease protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 762221..763081 Spirochaeta smaragdinae DSM 11293 9488813 YP_003802463.1 CDS Spirs_0734 NC_014364.1 763084 763896 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: smd:Smed_2454 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: permease abc transporter protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 763084..763896 Spirochaeta smaragdinae DSM 11293 9488814 YP_003802464.1 CDS Spirs_0735 NC_014364.1 763893 765143 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sma:SAV_2248 transcriptional regulator; PFAM: ROK family protein; SPTR: ROK-family transcriptional regulator; PFAM: ROK family; ROK family protein 763893..765143 Spirochaeta smaragdinae DSM 11293 9488815 YP_003802465.1 CDS Spirs_0736 NC_014364.1 765251 766720 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485:IPR018483; KEGG: rrs:RoseRS_4551 carbohydrate kinase, FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 765251..766720 Spirochaeta smaragdinae DSM 11293 9488816 YP_003802466.1 CDS Spirs_0737 NC_014364.1 766707 767549 D COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: mta:Moth_2404 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase 766707..767549 Spirochaeta smaragdinae DSM 11293 9488817 YP_003802467.1 CDS Spirs_0738 NC_014364.1 767574 768863 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gyc:GYMC61_2731 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 767574..768863 Spirochaeta smaragdinae DSM 11293 9488818 YP_003802468.1 CDS Spirs_0739 NC_014364.1 768882 769610 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: cai:Caci_2610 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 768882..769610 Spirochaeta smaragdinae DSM 11293 9488819 YP_003802469.1 CDS Spirs_0740 NC_014364.1 769603 770445 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: csc:Csac_2740 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 769603..770445 Spirochaeta smaragdinae DSM 11293 9488820 YP_003802470.1 CDS Spirs_0741 NC_014364.1 770448 771401 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173:IPR002139; KEGG: ypb:YPTS_1817 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: sugar kinase; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 770448..771401 Spirochaeta smaragdinae DSM 11293 9488821 YP_003802471.1 CDS Spirs_0742 NC_014364.1 771398 772018 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: sat:SYN_01953 response regulator; PFAM: regulatory protein LuxR; response regulator receiver; SMART: regulatory protein LuxR; response regulator receiver; SPTR: Response regulator with a HTH DNA-binding domain; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 771398..772018 Spirochaeta smaragdinae DSM 11293 9488822 YP_003802472.1 CDS Spirs_0743 NC_014364.1 772039 772785 R InterPro IPR002781; KEGG: cbe:Cbei_3952 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE; hypothetical protein complement(772039..772785) Spirochaeta smaragdinae DSM 11293 9488823 YP_003802473.1 CDS Spirs_0744 NC_014364.1 772816 773484 R InterPro IPR001387:IPR013096; KEGG: cdl:CDR20291_1542 transcriptional regulator; PFAM: Cupin 2 conserved barrel domain protein; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Probable transcriptional regulator; PFAM: Cupin domain; Helix-turn-helix; XRE family transcriptional regulator complement(772816..773484) Spirochaeta smaragdinae DSM 11293 9488824 YP_003802474.1 CDS Spirs_0745 NC_014364.1 773883 774707 D COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: tpt:Tpet_0504 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: sugar phosphate isomerase/epimerase; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase 773883..774707 Spirochaeta smaragdinae DSM 11293 9488825 YP_003802475.1 CDS Spirs_0746 NC_014364.1 774720 775916 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR002328; KEGG: tpe:Tpen_0821 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 774720..775916 Spirochaeta smaragdinae DSM 11293 9488826 YP_003802476.1 CDS Spirs_0747 NC_014364.1 775916 776893 D COGs: COG1402 Uncharacterized protein amidase; InterPro IPR003785; KEGG: tnp:Tnap_0205 creatininase; PFAM: creatininase; SPTR: creatininase; PFAM: Creatinine amidohydrolase; creatininase 775916..776893 Spirochaeta smaragdinae DSM 11293 9488827 YP_003802477.1 CDS Spirs_0748 NC_014364.1 776957 778015 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR002328; KEGG: gym:GYMC10_0694 alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; SPTR: uncharacterized protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 776957..778015 Spirochaeta smaragdinae DSM 11293 9488828 YP_003802478.1 CDS Spirs_0749 NC_014364.1 778096 778923 D COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: stm:STM4427 endonuclease; PFAM: xylose isomerase; SPTR: endonuclease; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase 778096..778923 Spirochaeta smaragdinae DSM 11293 9488829 YP_003802479.1 CDS Spirs_0750 NC_014364.1 778977 780080 D COGs: COG4213 ABC-type xylose transporter periplasmic component; KEGG: tex:Teth514_0155 D-xylose ABC transporter periplasmic substrate-binding protein; SPTR: D-xylose ABC transporter periplasmic substrate-binding protein; PFAM: family; TIGRFAM: D-xylose ABC transporter substrate-binding protein; D-xylose ABC transporter periplasmic substrate-binding protein 778977..780080 Spirochaeta smaragdinae DSM 11293 9488830 YP_003802480.1 CDS Spirs_0751 NC_014364.1 780109 781716 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: tit:Thit_0247 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 780109..781716 Spirochaeta smaragdinae DSM 11293 9488831 YP_003802481.1 CDS Spirs_0752 NC_014364.1 781722 782900 D COGs: COG4214 ABC-type xylose transporter permease component; InterPro IPR001851; KEGG: mta:Moth_2020 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 781722..782900 Spirochaeta smaragdinae DSM 11293 9488832 YP_003802482.1 CDS Spirs_0753 NC_014364.1 782915 783937 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: hap:HAPS_1534 myoinositol 2-dehydrogenase with oxidoreductase domain; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: inositol 2-dehydrogenase; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 782915..783937 Spirochaeta smaragdinae DSM 11293 9488833 YP_003802483.1 CDS Spirs_0754 NC_014364.1 784163 785116 D COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: uncharacterized protein yfiH; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel; xylose isomerase 784163..785116 Spirochaeta smaragdinae DSM 11293 9488834 YP_003802484.1 CDS Spirs_0755 NC_014364.1 785400 786590 D COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: lbl:LBL_2119 hypothetical protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: uncharacterized protein; PFAM: Fic/DOC family; filamentation induced by cAMP protein Fic 785400..786590 Spirochaeta smaragdinae DSM 11293 9488835 YP_003802485.1 CDS Spirs_0756 NC_014364.1 786583 787473 D COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR010499:IPR018062:IPR018060; KEGG: cbl:CLK_0114 AraC family transcriptional regulator; PFAM: transcription activator effector binding; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator, AraC family; PFAM: Bacterial transcription activator, effector binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 786583..787473 Spirochaeta smaragdinae DSM 11293 9488836 YP_003802486.1 CDS Spirs_0757 NC_014364.1 787517 788857 D COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528:IPR005829; KEGG: cdf:CD3361 multidrug efflux protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: multidrug efflux protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; multi antimicrobial extrusion protein MatE 787517..788857 Spirochaeta smaragdinae DSM 11293 9488837 YP_003802487.1 CDS Spirs_0758 NC_014364.1 788869 789603 R COGs: COG0546 phosphatase; InterPro IPR005834:IPR006439; KEGG: bai:BAA_0380 haloacid dehalogenase/epoxide hydrolase family protein; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD-superfamily hydrolase complement(788869..789603) Spirochaeta smaragdinae DSM 11293 9488838 YP_003802488.1 CDS Spirs_0759 NC_014364.1 789600 790253 R COGs: COG0352 thiamine monophosphate synthase; InterPro IPR003733; KEGG: msi:Msm_0917 thiamine monophosphate synthase, ThiE; PFAM: thiamine monophosphate synthase; SPTR: thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; PFAM: thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase; thiamine-phosphate pyrophosphorylase complement(789600..790253) Spirochaeta smaragdinae DSM 11293 9488839 YP_003802489.1 CDS Spirs_0760 NC_014364.1 790246 791052 R COGs: COG2145 hydroxyethylthiazole kinase sugar kinase family; InterPro IPR000417:IPR011144; KEGG: cce:Ccel_1990 hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase; PRIAM: hydroxyethylthiazole kinase; SPTR: hydroxyethylthiazole kinase; PFAM: hydroxyethylthiazole kinase family; TIGRFAM: hydroxyethylthiazole kinase; hydroxyethylthiazole kinase complement(790246..791052) Spirochaeta smaragdinae DSM 11293 9488840 YP_003802490.1 CDS Spirs_0761 NC_014364.1 791034 792260 R COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: ccu:Ccur_09360 probable hydroxymethylpyrimidine transporter CytX; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: Probable hydroxymethylpyrimidine transporter CytX; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: probable hydroxymethylpyrimidine transporter CytX; cytosine/purines uracil thiamine allantoin permease complement(791034..792260) Spirochaeta smaragdinae DSM 11293 9488841 YP_003802491.1 CDS Spirs_0762 NC_014364.1 792257 793105 R COGs: COG0351 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR013749:IPR004399; KEGG: sdl:Sdel_1176 phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase type-1; PRIAM: phosphomethylpyrimidine kinase; SPTR: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; phosphomethylpyrimidine kinase complement(792257..793105) Spirochaeta smaragdinae DSM 11293 9488842 YP_003802492.1 CDS Spirs_0763 NC_014364.1 793406 794041 R COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: smd:Smed_5464 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase complement(793406..794041) Spirochaeta smaragdinae DSM 11293 9488843 YP_003802493.1 CDS Spirs_0764 NC_014364.1 794295 795089 D KEGG: cpf:CPF_1304 hypothetical protein; SPTR: methyltransferase; hypothetical protein 794295..795089 Spirochaeta smaragdinae DSM 11293 9488844 YP_003802494.1 CDS Spirs_0765 NC_014364.1 795154 796674 D COGs: COG3497 Phage tail sheath protein FI; InterPro IPR007067; KEGG: ddc:Dd586_3461 tail sheath protein; PFAM: tail sheath protein; SPTR: Tail sheath protein; PFAM: Phage tail sheath protein; tail sheath protein 795154..796674 Spirochaeta smaragdinae DSM 11293 9488845 YP_003802495.1 CDS Spirs_0766 NC_014364.1 796615 796857 R KEGG: ame:411163 similar to Nat1 CG12202-PA; hypothetical protein complement(796615..796857) Spirochaeta smaragdinae DSM 11293 9488846 YP_003802496.1 CDS Spirs_0767 NC_014364.1 796882 798018 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dhd:Dhaf_0017 diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(796882..798018) Spirochaeta smaragdinae DSM 11293 9488847 YP_003802497.1 CDS Spirs_0768 NC_014364.1 798188 798751 R COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mac:MA4620 hypothetical protein; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain; type 11 methyltransferase complement(798188..798751) Spirochaeta smaragdinae DSM 11293 9488848 YP_003802498.1 CDS Spirs_0769 NC_014364.1 798738 799094 R KEGG: rbi:RB2501_05580 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(798738..799094) Spirochaeta smaragdinae DSM 11293 9488849 YP_003802499.1 CDS Spirs_0770 NC_014364.1 799081 799626 R COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: aba:acid345_3448 ECF subfamily RNA polymerase sigma-24 factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Sigma-24, ECF subfamily; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit complement(799081..799626) Spirochaeta smaragdinae DSM 11293 9488850 YP_003802500.1 CDS Spirs_0771 NC_014364.1 799829 800761 R COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase complement(799829..800761) Spirochaeta smaragdinae DSM 11293 9488851 YP_003802501.1 CDS Spirs_0772 NC_014364.1 801017 801784 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: csc:Csac_0357 2-deoxy-D-gluconate 3-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: uncharacterized protein; PFAM: short chain dehydrogenase; TIGRFAM: 2-deoxy-D-gluconate 3-dehydrogenase; short-chain dehydrogenase/reductase SDR 801017..801784 Spirochaeta smaragdinae DSM 11293 9488852 YP_003802502.1 CDS Spirs_0773 NC_014364.1 801803 802747 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: ach:Achl_3701 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: uncharacterized protein; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 801803..802747 Spirochaeta smaragdinae DSM 11293 9488853 YP_003802503.1 CDS Spirs_0774 NC_014364.1 802752 803642 D COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: ach:Achl_3700 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: uncharacterized protein; PFAM: AP endonuclease family 2 C terminus; Xylose isomerase-like TIM barrel; xylose isomerase 802752..803642 Spirochaeta smaragdinae DSM 11293 9488854 YP_003802504.1 CDS Spirs_0775 NC_014364.1 803683 804654 D COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: ecz:ECS88_4278 periplasmic binding protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein 803683..804654 Spirochaeta smaragdinae DSM 11293 9488855 YP_003802505.1 CDS Spirs_0776 NC_014364.1 804717 805175 D KEGG: pmr:PMI2936 hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctB family; hypothetical protein 804717..805175 Spirochaeta smaragdinae DSM 11293 9488856 YP_003802506.1 CDS Spirs_0777 NC_014364.1 805197 806714 D COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: pmr:PMI2935 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); hypothetical protein 805197..806714 Spirochaeta smaragdinae DSM 11293 9488857 YP_003802507.1 CDS Spirs_0778 NC_014364.1 806714 807145 D InterPro IPR001310; KEGG: cbe:Cbei_4080 histidine triad (HIT) protein; SPTR: uncharacterized protein; histidine triad (HIT) protein 806714..807145 Spirochaeta smaragdinae DSM 11293 9488858 YP_003802508.1 CDS Spirs_0779 NC_014364.1 807149 808108 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: gym:GYMC10_3582 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 807149..808108 Spirochaeta smaragdinae DSM 11293 9488859 YP_003802509.1 CDS Spirs_0780 NC_014364.1 808286 809248 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: lci:LCK_00457 carbon catabolite control protein; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; LacI family transcriptional regulator 808286..809248 Spirochaeta smaragdinae DSM 11293 9488860 YP_003802510.1 CDS Spirs_0781 NC_014364.1 809252 810157 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR018187; KEGG: bgl:bglu_2g08900 ribokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 809252..810157 Spirochaeta smaragdinae DSM 11293 9488861 YP_003802511.1 CDS Spirs_0782 NC_014364.1 810154 811119 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: dap:Dacet_0215 LacI family transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 810154..811119 Spirochaeta smaragdinae DSM 11293 9488862 YP_003802512.1 CDS Spirs_0783 NC_014364.1 811273 812109 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ret:RHE_CH01557 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Probable sugar ABC transporter permease protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(811273..812109) Spirochaeta smaragdinae DSM 11293 9488863 YP_003802513.1 CDS Spirs_0784 NC_014364.1 812102 812992 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pam:PANA_0320 YurN; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: YurN; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(812102..812992) Spirochaeta smaragdinae DSM 11293 9488864 YP_003802514.1 CDS Spirs_0785 NC_014364.1 812985 814340 R COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088:IPR019802; KEGG: str:Sterm_4107 glycoside hydrolase family 4; PFAM: glycoside hydrolase family 4; SPTR: uncharacterized protein; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; glycoside hydrolase family protein complement(812985..814340) Spirochaeta smaragdinae DSM 11293 9488865 YP_003802515.1 CDS Spirs_0786 NC_014364.1 814337 815281 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: sgr:SGR_5001 carbohydrate kinase; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(814337..815281) Spirochaeta smaragdinae DSM 11293 9488866 YP_003802516.1 CDS Spirs_0787 NC_014364.1 815346 816626 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ttr:Tter_1291 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(815346..816626) Spirochaeta smaragdinae DSM 11293 9488867 YP_003802517.1 CDS Spirs_0788 NC_014364.1 816733 817761 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tit:Thit_1753 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(816733..817761) Spirochaeta smaragdinae DSM 11293 9488868 YP_003802518.1 CDS Spirs_0789 NC_014364.1 818020 819393 D COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016160:IPR012394; KEGG: dsy:DSY1102 hypothetical protein; PFAM: aldehyde dehydrogenase; SPTR: uncharacterized protein; PFAM: aldehyde dehydrogenase family; aldehyde dehydrogenase 818020..819393 Spirochaeta smaragdinae DSM 11293 9488869 YP_003802519.1 CDS Spirs_0790 NC_014364.1 819396 820127 R COGs: COG1609 transcriptional regulators; KEGG: sus:acid_2068 GntR family transcriptional regulator; SPTR: transcriptional regulator; PFAM: family; GntR family transcriptional regulator complement(819396..820127) Spirochaeta smaragdinae DSM 11293 9488870 YP_003802520.1 CDS Spirs_0791 NC_014364.1 820369 821073 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: amt:Amet_0818 GntR domain-containing protein; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 820369..821073 Spirochaeta smaragdinae DSM 11293 9488871 YP_003802521.1 CDS Spirs_0792 NC_014364.1 821141 822067 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR005263; KEGG: dau:Daud_0946 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: uncharacterized protein; TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase; dihydrodipicolinate synthase 821141..822067 Spirochaeta smaragdinae DSM 11293 9488872 YP_003802522.1 CDS Spirs_0793 NC_014364.1 822080 822961 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: kcr:Kcr_0361 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: uncharacterized protein; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 822080..822961 Spirochaeta smaragdinae DSM 11293 9488873 YP_003802523.1 CDS Spirs_0794 NC_014364.1 823031 823996 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: dat:HRM2_15300 ABC-type amino acid transporter periplasmic amino acid-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: ABC-type amino acid transporter periplasmic amino acid-binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein 823031..823996 Spirochaeta smaragdinae DSM 11293 9488874 YP_003802524.1 CDS Spirs_0795 NC_014364.1 824084 824836 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: cyb:CYB_0933 polar amino acid ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: Polar amino amino acid ABC transporter (PAAT) family, ATP-binding protein; PFAM: ABC transporter; ABC transporter 824084..824836 Spirochaeta smaragdinae DSM 11293 9488875 YP_003802525.1 CDS Spirs_0796 NC_014364.1 824879 825538 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: aco:Amico_0415 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Amino acid ABC superfamily ATP binding cassette transporter amino acid-binding/permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane protein 824879..825538 Spirochaeta smaragdinae DSM 11293 9488876 YP_003802526.1 CDS Spirs_0797 NC_014364.1 825553 826215 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: dat:HRM2_15310 ABC-type amino acid transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type amino acid transporter permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane protein 825553..826215 Spirochaeta smaragdinae DSM 11293 9488877 YP_003802527.1 CDS Spirs_0798 NC_014364.1 826226 827344 D COGs: COG0075 serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR017972; KEGG: dau:Daud_0011 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase, class V; PFAM: Aminotransferase class-V; class V aminotransferase 826226..827344 Spirochaeta smaragdinae DSM 11293 9488878 YP_003802528.1 CDS Spirs_0799 NC_014364.1 827353 828402 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002139; KEGG: ctc:CTC00909 ribokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase; PfkB domain-containing protein 827353..828402 Spirochaeta smaragdinae DSM 11293 9488879 YP_003802529.1 CDS Spirs_0800 NC_014364.1 828412 829053 D COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: apv:Apar_1282 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain; sugar isomerase (SIS) 828412..829053 Spirochaeta smaragdinae DSM 11293 9488880 YP_003802530.1 CDS Spirs_0801 NC_014364.1 829047 829451 D InterPro IPR007721; KEGG: ctc:CTC00903 hypothetical protein; PFAM: RbsD or FucU transport; SPTR: uncharacterized protein; PFAM: RbsD / FucU transporter family; RbsD or FucU transporter 829047..829451 Spirochaeta smaragdinae DSM 11293 9488881 YP_003802531.1 CDS Spirs_0802 NC_014364.1 829594 830268 R COGs: COG1802 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: chy:CHY_0189 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator, GntR family; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(829594..830268) Spirochaeta smaragdinae DSM 11293 9488882 YP_003802532.1 CDS Spirs_0803 NC_014364.1 830446 831360 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR020625; KEGG: rle:RL4484 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 830446..831360 Spirochaeta smaragdinae DSM 11293 9488883 YP_003802533.1 CDS Spirs_0804 NC_014364.1 831453 832763 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cpo:COPRO5265_1549 trehalose/maltose binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Trehalose/maltose binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 831453..832763 Spirochaeta smaragdinae DSM 11293 9488884 YP_003802534.1 CDS Spirs_0805 NC_014364.1 832892 833776 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tit:Thit_0425 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 832892..833776 Spirochaeta smaragdinae DSM 11293 9488885 YP_003802535.1 CDS Spirs_0806 NC_014364.1 833802 834644 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: mlo:mlr7227 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC superfamily ATP binding cassette transporter membrane protein; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 833802..834644 Spirochaeta smaragdinae DSM 11293 9488886 YP_003802536.1 CDS Spirs_0807 NC_014364.1 834788 837184 R COGs: COG1912 conserved hypothetical protein; InterPro IPR018392:IPR002482; KEGG: apv:Apar_0178 protein tyrosine/serine phosphatase; PFAM: peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: uncharacterized protein; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase; LysM domain; peptidoglycan-binding lysin domain-containing protein complement(834788..837184) Spirochaeta smaragdinae DSM 11293 9488887 YP_003802537.1 CDS Spirs_0808 NC_014364.1 837833 838450 D KEGG: nfa:nfa7010 transcriptional regulator; SPTR: transcriptional regulator; PFAM: shikimate kinase; hypothetical protein 837833..838450 Spirochaeta smaragdinae DSM 11293 9488888 YP_003802538.1 CDS Spirs_0809 NC_014364.1 838556 839830 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: tle:Tlet_1705 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 838556..839830 Spirochaeta smaragdinae DSM 11293 9488889 YP_003802539.1 CDS Spirs_0810 NC_014364.1 839868 840815 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tle:Tlet_1706 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; sugar ABC transporter permease 839868..840815 Spirochaeta smaragdinae DSM 11293 9488890 YP_003802540.1 CDS Spirs_0811 NC_014364.1 840812 841648 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tle:Tlet_1707 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permeasent 840812..841648 Spirochaeta smaragdinae DSM 11293 9488891 YP_003802541.1 CDS Spirs_0812 NC_014364.1 841673 842638 D COGs: COG2390 transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: tle:Tlet_1708 DeoR family transcriptional regulator; PFAM: sugar-binding domain protein; SPTR: DeoR family transcriptional regulator; PFAM: sugar-binding domain; DeoR family transcriptional regulator 841673..842638 Spirochaeta smaragdinae DSM 11293 9488892 YP_003802542.1 CDS Spirs_0813 NC_014364.1 842641 843600 D COGs: COG1105 fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR018486; KEGG: tle:Tlet_1709 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; PfkB domain-containing protein 842641..843600 Spirochaeta smaragdinae DSM 11293 9488893 YP_003802543.1 CDS Spirs_0814 NC_014364.1 843578 845032 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: tle:Tlet_1710 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 843578..845032 Spirochaeta smaragdinae DSM 11293 9488894 YP_003802544.1 CDS Spirs_0815 NC_014364.1 845090 845947 D COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: tle:Tlet_1711 ketose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: Ketose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase 845090..845947 Spirochaeta smaragdinae DSM 11293 9488895 YP_003802545.1 CDS Spirs_0816 NC_014364.1 846009 846863 R COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase complement(846009..846863) Spirochaeta smaragdinae DSM 11293 9488896 YP_003802546.1 CDS Spirs_0817 NC_014364.1 846892 847839 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: mrb:Mrub_1270 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein complement(846892..847839) Spirochaeta smaragdinae DSM 11293 9488897 YP_003802547.1 CDS Spirs_0818 NC_014364.1 847832 848353 R KEGG: ttr:Tter_2376 hypothetical protein; SPTR: uncharacterized protein; PFAM: Chromatin associated protein KTI12; hypothetical protein complement(847832..848353) Spirochaeta smaragdinae DSM 11293 9488898 YP_003802548.1 CDS Spirs_0819 NC_014364.1 848373 849065 R COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: rle:pRL120033 D-allulose-6-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: ribulose-phosphate 3-epimerase; SPTR: D-allulose-6-phosphate 3-epimerase; PFAM: ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase complement(848373..849065) Spirochaeta smaragdinae DSM 11293 9488899 YP_003802549.1 CDS Spirs_0820 NC_014364.1 849154 850110 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: dfe:Dfer_3164 monosaccharide-transporting ATPase; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: sugar ATP transporter ATPase; PFAM: family; periplasmic binding protein/LacI transcriptional regulator complement(849154..850110) Spirochaeta smaragdinae DSM 11293 9488900 YP_003802550.1 CDS Spirs_0821 NC_014364.1 850184 851152 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: bha:BH2321 sugar ABC transporter (permease); PFAM: inner-membrane translocator; SPTR: Sugar ABC transporter (Permease); PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(850184..851152) Spirochaeta smaragdinae DSM 11293 9488901 YP_003802551.1 CDS Spirs_0822 NC_014364.1 851156 852655 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: bha:BH2322 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ribose/galactose/methyl galactoside import ATP-binding protein 2; PFAM: ABC transporter; ABC transporter complement(851156..852655) Spirochaeta smaragdinae DSM 11293 9488902 YP_003802552.1 CDS Spirs_0823 NC_014364.1 852830 853627 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: tte:TTE1945 sugar metabolism transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: transcriptional regulator of sugar metabolism; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 852830..853627 Spirochaeta smaragdinae DSM 11293 9488903 YP_003802553.1 CDS Spirs_0824 NC_014364.1 853715 853879 R hypothetical protein complement(853715..853879) Spirochaeta smaragdinae DSM 11293 9488904 YP_003802554.1 CDS Spirs_0825 NC_014364.1 853913 855103 R COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: sed:SeD_A4225 mandelate racemase/muconate lactonizing enzyme family protein; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: uncharacterized protein; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; mandelate racemase / muconate lactonizing enzyme, N-terminal domain; mandelate racemase/muconate lactonizing protein complement(853913..855103) Spirochaeta smaragdinae DSM 11293 9488905 YP_003802555.1 CDS Spirs_0826 NC_014364.1 855100 856227 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: met:M446_1233 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(855100..856227) Spirochaeta smaragdinae DSM 11293 9488906 YP_003802556.1 CDS Spirs_0827 NC_014364.1 856289 857782 R COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: rsk:RSKD131_3574 TRAP-T family transporter large (12 TMs) inner membrane subunit; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein complement(856289..857782) Spirochaeta smaragdinae DSM 11293 9488907 YP_003802557.1 CDS Spirs_0828 NC_014364.1 857801 858274 R KEGG: tle:Tlet_0634 hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctB family; hypothetical protein complement(857801..858274) Spirochaeta smaragdinae DSM 11293 9488908 YP_003802558.1 CDS Spirs_0829 NC_014364.1 858349 859323 R COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: ebr:ECB_03721 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Uncharacterized protein UPF0065; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein complement(858349..859323) Spirochaeta smaragdinae DSM 11293 9488909 YP_003802559.1 CDS Spirs_0830 NC_014364.1 859320 860333 R COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013116:IPR000506:IPR013023; KEGG: sso:SSO1322 ketol-acid reductoisomerase (IlvC-2); PFAM: acetohydroxy acid isomeroreductase catalytic domain protein; acetohydroxy acid isomeroreductase; PRIAM: Ketol-acid reductoisomerase; SPTR: ketol-acid reductoisomerase 2; TIGRFAM: ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; ketol-acid reductoisomerase complement(859320..860333) Spirochaeta smaragdinae DSM 11293 9488910 YP_003802560.1 CDS Spirs_0831 NC_014364.1 860465 861166 D COGs: COG1802 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: tit:Thit_2226 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Predicted protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 860465..861166 Spirochaeta smaragdinae DSM 11293 9488911 YP_003802561.1 CDS Spirs_0832 NC_014364.1 861271 862353 D COGs: COG1609 transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: cbe:Cbei_4456 regulatory protein GntR, HTH; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: Regulatory protein GntR HTH; manually curated; PFAM: Bacterial regulatory proteins, gntR family; family; GntR family transcriptional regulator 861271..862353 Spirochaeta smaragdinae DSM 11293 9488912 YP_003802562.1 CDS Spirs_0833 NC_014364.1 862596 863729 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: pfs:PFLU3996 sugar-binding exported protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: uncharacterized protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 862596..863729 Spirochaeta smaragdinae DSM 11293 9488913 YP_003802563.1 CDS Spirs_0834 NC_014364.1 863806 864762 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: dtu:Dtur_0412 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 863806..864762 Spirochaeta smaragdinae DSM 11293 9488914 YP_003802564.1 CDS Spirs_0835 NC_014364.1 864782 866284 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: bcb:BCB4264_A0699 ribose ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ribose ABC transporter; PFAM: ABC transporter; ABC transporter 864782..866284 Spirochaeta smaragdinae DSM 11293 9488915 YP_003802565.1 CDS Spirs_0836 NC_014364.1 866297 867256 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: oih:OB2573 ribose ABC transporter permease; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 866297..867256 Spirochaeta smaragdinae DSM 11293 9488916 YP_003802566.1 CDS Spirs_0837 NC_014364.1 867274 868620 D COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: dth:DICTH_0275 alpha-galactosidase; PFAM: glycoside hydrolase family 4; SPTR: alpha-galactosidase; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; glycoside hydrolase family protein 867274..868620 Spirochaeta smaragdinae DSM 11293 9488917 YP_003802567.1 CDS Spirs_0838 NC_014364.1 868854 869753 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: dge:Dgeo_2664 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type sugar transport system, permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(868854..869753) Spirochaeta smaragdinae DSM 11293 9488918 YP_003802568.1 CDS Spirs_0839 NC_014364.1 869758 870702 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: dge:Dgeo_2663 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type sugar transport system, permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(869758..870702) Spirochaeta smaragdinae DSM 11293 9488919 YP_003802569.1 CDS Spirs_0840 NC_014364.1 870795 872120 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: dge:Dgeo_2662 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(870795..872120) Spirochaeta smaragdinae DSM 11293 9488920 YP_003802570.1 CDS Spirs_0841 NC_014364.1 872452 873465 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: oan:Oant_4373 regulatory protein LacI; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Regulatory protein LacI; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(872452..873465) Spirochaeta smaragdinae DSM 11293 9488921 YP_003802571.1 CDS Spirs_0842 NC_014364.1 873579 874673 D COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: tle:Tlet_1019 basic membrane lipoprotein; PFAM: basic membrane lipoprotein; SPTR: lipid ABC superfamily ATP binding cassette transporter binding protein; PFAM: Basic membrane protein; basic membrane lipoprotein 873579..874673 Spirochaeta smaragdinae DSM 11293 9488922 YP_003802572.1 CDS Spirs_0843 NC_014364.1 874687 876213 D COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003439:IPR003593; KEGG: clo:HMPREF0868_0265 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC-type sugar transporter; PFAM: ABC transporter; ABC transporter 874687..876213 Spirochaeta smaragdinae DSM 11293 9488923 YP_003802573.1 CDS Spirs_0844 NC_014364.1 876210 877253 D COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: tle:Tlet_1021 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 876210..877253 Spirochaeta smaragdinae DSM 11293 9488924 YP_003802574.1 CDS Spirs_0845 NC_014364.1 877255 878175 D COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: kol:Kole_1253 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 877255..878175 Spirochaeta smaragdinae DSM 11293 9488925 YP_003802575.1 CDS Spirs_0846 NC_014364.1 878172 879131 D COGs: COG1957 inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910:IPR015910; KEGG: shl:Shal_2421 ribonucleoside hydrolase 1; PFAM: inosine/uridine-preferring nucleoside hydrolase; SPTR: inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine-uridine preferring nucleoside hydrolase; inosine/uridine-preferring nucleoside hydrolase 878172..879131 Spirochaeta smaragdinae DSM 11293 9488926 YP_003802576.1 CDS Spirs_0847 NC_014364.1 879216 880292 D COGs: COG3191 L-aminopeptidase/D-esterase; InterPro IPR005321; KEGG: azc:AZC_2992 D-aminopeptidase; PFAM: peptidase S58 DmpA; SPTR: peptidase S58 DmpA; PFAM: peptidase family S58; peptidase S58 DmpA 879216..880292 Spirochaeta smaragdinae DSM 11293 9488927 YP_003802577.1 CDS Spirs_0848 NC_014364.1 880598 882541 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953:IPR010960; KEGG: dal:Dalk_0748 flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: Flavocytochrome C; TIGRFAM: flavocytochrome C; PFAM: FAD binding domain; FMN-binding domain; TIGRFAM: flavocytochrome C; flavocytochrome C 880598..882541 Spirochaeta smaragdinae DSM 11293 9488928 YP_003802578.1 CDS Spirs_0849 NC_014364.1 882635 883450 D InterPro IPR000551; KEGG: dhd:Dhaf_1657 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: MerR family transcriptional regulator; PFAM: MerR family regulatory protein; MerR family transcriptional regulator 882635..883450 Spirochaeta smaragdinae DSM 11293 9488929 YP_003802579.1 CDS Spirs_0850 NC_014364.1 883540 885405 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953; KEGG: dap:Dacet_2091 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; FMN-binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 883540..885405 Spirochaeta smaragdinae DSM 11293 9488930 YP_003802580.1 CDS Spirs_0851 NC_014364.1 885434 887335 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953; KEGG: ddc:Dd586_0833 fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain; FMN-binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 885434..887335 Spirochaeta smaragdinae DSM 11293 9488931 YP_003802581.1 CDS Spirs_0852 NC_014364.1 887499 889085 D COGs: COG2199 FOG: GGDEF domain; InterPro IPR013656:IPR000160:IPR000014; KEGG: chl:Chy400_2795 diguanylate cyclase with GAF sensor; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; PAS/PAC sensor-containing diguanylate cyclase 887499..889085 Spirochaeta smaragdinae DSM 11293 9488932 YP_003802582.1 CDS Spirs_0853 NC_014364.1 889182 890357 D COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR001670:IPR018211; KEGG: cth:Cthe_0101 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 889182..890357 Spirochaeta smaragdinae DSM 11293 9488933 YP_003802583.1 CDS Spirs_0854 NC_014364.1 890372 892516 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR004010:IPR003660:IPR000160; KEGG: cbe:Cbei_2424 diguanylate cyclase/phosphodiesterase; PFAM: GGDEF domain containing protein; Cache domain protein; histidine kinase HAMP region domain protein; SMART: GGDEF domain containing protein; SPTR: diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: Cache domain; GGDEF domain; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(890372..892516) Spirochaeta smaragdinae DSM 11293 9488934 YP_003802584.1 CDS Spirs_0855 NC_014364.1 892529 893959 R COGs: COG1653 ABC-type sugar transporter periplasmic component; KEGG: cdl:CDR20291_0675 lipoprotein; SPTR: peroxiredoxin; lipoprotein complement(892529..893959) Spirochaeta smaragdinae DSM 11293 9488935 YP_003802585.1 CDS Spirs_0856 NC_014364.1 894373 896178 D COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR018982:IPR002121:IPR 014001:IPR014021:IPR006293:IPR018329; KEGG: cpb:Cphamn1_0072 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase; helicase domain protein; RQC domain; HRDC domain protein; SMART: DEAD-like helicase ; helicase domain protein; HRDC domain protein; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ 894373..896178 Spirochaeta smaragdinae DSM 11293 9488936 YP_003802586.1 CDS Spirs_0857 NC_014364.1 896472 897113 D KEGG: efa:EF3051 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 896472..897113 Spirochaeta smaragdinae DSM 11293 9488937 YP_003802587.1 CDS Spirs_0858 NC_014364.1 897103 897699 R COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: ppr:PBPRA0299 hypothetical protein; PFAM: lysine exporter protein (LYSE/YGGA); SPTR: uncharacterized protein; PFAM: LysE type translocator; lysine exporter LysE/YggA complement(897103..897699) Spirochaeta smaragdinae DSM 11293 9488938 YP_003802588.1 CDS Spirs_0859 NC_014364.1 897805 899223 D COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524:IPR004839:IPR003114; KEGG: syn:sll5086 GntR family transcriptional regulatory protein; PFAM: aminotransferase class I and II; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulatory protein; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II; GntR family transcriptional regulator 897805..899223 Spirochaeta smaragdinae DSM 11293 9488939 YP_003802589.1 CDS Spirs_0860 NC_014364.1 899392 901608 R COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953; KEGG: amt:Amet_3859 fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PFAM: FAD binding domain; FMN-binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein complement(899392..901608) Spirochaeta smaragdinae DSM 11293 9488940 YP_003802590.1 CDS Spirs_0862 NC_014364.1 903155 903844 R KEGG: cyh:Cyan8802_1384 histidyl-tRNA synthetase 2; SPTR: Histidyl-tRNA synthetase 2; hypothetical protein complement(903155..903844) Spirochaeta smaragdinae DSM 11293 9488942 YP_003802591.1 CDS Spirs_0863 NC_014364.1 903928 904701 R KEGG: pmf:P9303_14591 cell division protein FtsH4; SPTR: cell division protein FtsH4; hypothetical protein complement(903928..904701) Spirochaeta smaragdinae DSM 11293 9488943 YP_003802592.1 CDS Spirs_0864 NC_014364.1 904716 905414 R KEGG: tet:TTHERM_00648760 protein kinase domain containing protein; SPTR: ankyrin repeat; hypothetical protein complement(904716..905414) Spirochaeta smaragdinae DSM 11293 9488944 YP_003802593.1 CDS Spirs_0865 NC_014364.1 905524 907152 R KEGG: pfa:MAL13P1.32 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(905524..907152) Spirochaeta smaragdinae DSM 11293 9488945 YP_003802594.1 CDS Spirs_0866 NC_014364.1 907300 908007 D KEGG: cyh:Cyan8802_0186 6-phosphofructokinase; SPTR: molybdenum transport ATP-binding protein ModF; hypothetical protein 907300..908007 Spirochaeta smaragdinae DSM 11293 9488946 YP_003802595.1 CDS Spirs_0867 NC_014364.1 908047 908949 D InterPro IPR004843; KEGG: mgm:Mmc1_0230 hypothetical protein; PFAM: metallophosphoesterase; SPTR: uncharacterized protein; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase 908047..908949 Spirochaeta smaragdinae DSM 11293 9488947 YP_003802596.1 CDS Spirs_0868 NC_014364.1 908942 909877 D KEGG: pfh:PFHG_03001 malaria antigen; SPTR: transcription factor with AP2 domain(S), ; TIGRFAM: DnaD and phage-associated domain; hypothetical protein 908942..909877 Spirochaeta smaragdinae DSM 11293 9488948 YP_003802597.1 CDS Spirs_0869 NC_014364.1 909878 911428 D InterPro IPR000719; KEGG: cbe:Cbei_1151 protein kinase; SPTR: protein kinase; serine/threonine protein kinase 909878..911428 Spirochaeta smaragdinae DSM 11293 9488949 YP_003802598.1 CDS Spirs_0870 NC_014364.1 911647 914127 D COGs: COG2909 ATP-dependent transcriptional regulator protein; InterPro IPR000792; KEGG: swo:Swol_1080 ATP-dependent transcriptional regulator-like protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: ATP-dependent transcriptional regulator-like protein; PFAM: Bacterial regulatory proteins, luxR family; ATP-dependent transcriptional regulator, MalT-like, LuxR family 911647..914127 Spirochaeta smaragdinae DSM 11293 9488950 YP_003802599.1 CDS Spirs_0871 NC_014364.1 914301 915017 D KEGG: cdu:CD36_23630 cell surface flocculin, SPTR: cell wall protein, (cell wall adhesin, ) (cell surface flocculin, ); hypothetical protein 914301..915017 Spirochaeta smaragdinae DSM 11293 9488951 YP_003802600.1 CDS Spirs_0872 NC_014364.1 915431 916798 D COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638:IPR006158; KEGG: sat:SYN_02176 Fe-S oxidoreductase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Fe-S oxidoreductase; PFAM: radical SAM superfamily; B12 binding domain; radical SAM protein 915431..916798 Spirochaeta smaragdinae DSM 11293 9488953 YP_003802601.1 CDS Spirs_0873 NC_014364.1 916804 917907 R COGs: COG0240 glycerol-3-phosphate dehydrogenase; InterPro IPR011128:IPR006109:IPR006168; KEGG: tde:TDE2090 NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: glycerol-3-phosphate dehydrogenase [NAD(P)+]; PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase domain-containing protein complement(916804..917907) Spirochaeta smaragdinae DSM 11293 9488954 YP_003802602.1 CDS Spirs_0874 NC_014364.1 917995 919518 D COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR007280:IPR001254:IPR001940; KEGG: ttr:Tter_2107 peptidase S1 and S6 chymotrypsin/Hap; PFAM: peptidase domain protein; peptidase S1 and S6 chymotrypsin/Hap; SPTR: peptidase S1 and S6 chymotrypsin/Hap; PFAM: Trypsin; Bacterial pre-peptidase C-terminal domain; peptidase domain-containing protein 917995..919518 Spirochaeta smaragdinae DSM 11293 9488955 YP_003802603.1 CDS Spirs_0875 NC_014364.1 919529 920125 R KEGG: adg:Adeg_1791 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(919529..920125) Spirochaeta smaragdinae DSM 11293 9488956 YP_003802604.1 CDS Spirs_0876 NC_014364.1 920265 920798 D COGs: COG2236 phosphoribosyltransferase; InterPro IPR000836; KEGG: ngk:NGK_2653 hypothetical protein; PFAM: phosphoribosyltransferase; SPTR: Purine/pyrimidine phosphoribosyltransferase family protein; PFAM: phosphoribosyl transferase domain; phosphoribosyltransferase 920265..920798 Spirochaeta smaragdinae DSM 11293 9488957 YP_003802605.1 CDS Spirs_0877 NC_014364.1 920795 921718 D COGs: COG1105 fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611; KEGG: edi:EDI_134140 Tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase, ; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; PfkB domain-containing protein 920795..921718 Spirochaeta smaragdinae DSM 11293 9488958 YP_003802606.1 CDS Spirs_0878 NC_014364.1 921718 922317 D COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: aba:acid345_2887 molybdenum cofactor guanylyltransferase; SPTR: Molybdenum cofactor guanylyltransferase; molybdenum cofactor guanylyltransferase 921718..922317 Spirochaeta smaragdinae DSM 11293 9488959 YP_003802607.1 CDS Spirs_0879 NC_014364.1 922310 923485 D COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018164:IPR012947:IPR018165; KEGG: tte:TTE0934 metal-dependent hydrolase; PFAM: Alanyl-tRNA synthetase, class IIc-like; threonyl/alanyl tRNA synthetase SAD; SPTR: Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain; PFAM: tRNA synthetases class II (A); Alanyl-tRNA synthetase, class IIc 922310..923485 Spirochaeta smaragdinae DSM 11293 9488960 YP_003802608.1 CDS Spirs_0880 NC_014364.1 923482 925059 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: tle:Tlet_0651 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SPTR: uncharacterized protein; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(923482..925059) Spirochaeta smaragdinae DSM 11293 9488961 YP_003802609.1 CDS Spirs_0881 NC_014364.1 925214 925495 D KEGG: dhd:Dhaf_4209 hypothetical protein; SPTR: uncharacterized protein; PFAM: PQ loop repeat; hypothetical protein 925214..925495 Spirochaeta smaragdinae DSM 11293 9488962 YP_003802610.1 CDS Spirs_0882 NC_014364.1 925524 927089 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR013655:IPR011495:IPR003594:IPR000014:IPR 001610:IPR005467:IPR000700; KEGG: ote:Oter_0386 multi-sensor hybrid histidine kinase; PFAM: PAS fold-3 domain protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: PAC repeat-containing protein; PAS domain containing protein; ATP-binding region ATPase domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 925524..927089 Spirochaeta smaragdinae DSM 11293 9488963 YP_003802611.1 CDS Spirs_0883 NC_014364.1 927111 928601 D COGs: COG0498 threonine synthase; InterPro IPR001926:IPR000634:IPR004450; KEGG: cbf:CLI_1715 threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; PRIAM: threonine synthase; SPTR: threonine synthase; TIGRFAM: threonine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; threonine synthase 927111..928601 Spirochaeta smaragdinae DSM 11293 9488964 YP_003802612.1 CDS Spirs_0884 NC_014364.1 928598 929809 D COGs: COG3635 phosphoglycerate mutase AP superfamily; InterPro IPR019304:IPR006124:IPR004456:IPR013371; KEGG: cth:Cthe_1292 phosphoglycerate mutase; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme domain protein; PRIAM: phosphoglycerate mutase; SPTR: Proposed homoserine kinase; TIGRFAM: proposed homoserine kinase; phosphonopyruvate decarboxylase-related protein; PFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; metalloenzyme superfamily; TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, archaeal form; proposed homoserine kinase; proposed homoserine kinase 928598..929809 Spirochaeta smaragdinae DSM 11293 9488965 YP_003802613.1 CDS Spirs_0885 NC_014364.1 929992 930996 D COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: ttu:TERTU_1059 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase 929992..930996 Spirochaeta smaragdinae DSM 11293 9488966 YP_003802614.1 CDS Spirs_0886 NC_014364.1 931028 932344 D KEGG: gtn:GTNG_3234 hypothetical protein; SPTR: uncharacterized protein; transcriptional regulator 931028..932344 Spirochaeta smaragdinae DSM 11293 9488967 YP_003802615.1 CDS Spirs_0887 NC_014364.1 932469 933785 D COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterProIPR002933:IPR011650:IPR006162:IPR017439:IPR 010168; KEGG: sth:STH1690 amino acid amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase, M20D family; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase 932469..933785 Spirochaeta smaragdinae DSM 11293 9488968 YP_003802616.1 CDS Spirs_0888 NC_014364.1 933814 934665 D KEGG: bcl:ABC3812 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3100); hypothetical protein 933814..934665 Spirochaeta smaragdinae DSM 11293 9488969 YP_003802617.1 CDS Spirs_0889 NC_014364.1 934658 935128 D KEGG: mru:mru_0581 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 934658..935128 Spirochaeta smaragdinae DSM 11293 9488970 YP_003802618.1 CDS Spirs_0890 NC_014364.1 935198 937513 R COGs: COG1554 Trehalose and maltose hydrolase ( phosphorylase); InterPro IPR005196:IPR005195:IPR005194:IPR017045; KEGG: hor:Hore_20830 kojibiose phosphorylase; PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; SPTR: Kojibiose phosphorylase; PFAM: glycosyl hydrolase family 65, C-terminal domain; glycosyl hydrolase family 65, N-terminal domain; glycosyl hydrolase family 65 central catalytic domain; glycoside hydrolase family protein complement(935198..937513) Spirochaeta smaragdinae DSM 11293 9488971 YP_003802619.1 CDS Spirs_0891 NC_014364.1 937652 938686 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tna:CTN_1371 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 937652..938686 Spirochaeta smaragdinae DSM 11293 9488972 YP_003802620.1 CDS Spirs_0892 NC_014364.1 938873 939955 D COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; InterPro IPR004506:IPR018318; KEGG: chl:Chy400_0725 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase-like; SPTR: tRNA-specific 2-thiouridylase mnmA; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase 938873..939955 Spirochaeta smaragdinae DSM 11293 9488973 YP_003802621.1 CDS Spirs_0893 NC_014364.1 940039 942600 D COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR013497:IPR000380:IPR006154:IPR 003601:IPR003602:IPR005733; KEGG: cyc:PCC7424_3437 DNA topoisomerase I; PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial; DNA topoisomerase I 940039..942600 Spirochaeta smaragdinae DSM 11293 9488974 YP_003802622.1 CDS Spirs_0894 NC_014364.1 942603 943451 R COGs: COG2267 lysophospholipase; InterPro IPR000073; KEGG: sal:Sala_0197 acylglycerol lipase; PFAM: alpha/beta hydrolase fold; SPTR: acylglycerol lipase; PFAM: lysophospholipase; alpha/beta hydrolase fold protein complement(942603..943451) Spirochaeta smaragdinae DSM 11293 9488975 YP_003802623.1 CDS Spirs_0895 NC_014364.1 943719 944978 D COGs: COG4175 ABC-type proline/glycine betaine transport system ATPase component; InterProIPR003439:IPR000644:IPR017871:IPR003593:IPR 005892; KEGG: hoh:Hoch_5466 glycine betaine/L-proline ABC transporter ATPase subunit; PFAM: ABC transporter; CBS domain containing protein; SMART: ATPase AAA; SPTR: glycine betaine/L-proline ABC transporter ATPase subunit; TIGRFAM: glycine betaine/L-proline ABC transporter ATPase subunit; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit; glycine betaine/L-proline ABC transporter ATPase subunit 943719..944978 Spirochaeta smaragdinae DSM 11293 9488976 YP_003802624.1 CDS Spirs_0896 NC_014364.1 944975 945829 D COGs: COG4176 ABC-type proline/glycine betaine transport system permease; InterPro IPR000515; KEGG: hoh:Hoch_5465 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 944975..945829 Spirochaeta smaragdinae DSM 11293 9488977 YP_003802625.1 CDS Spirs_0897 NC_014364.1 945863 946765 D COGs: COG2113 ABC-type proline/glycine betaine transport systems periplasmic components; InterPro IPR007210; KEGG: hoh:Hoch_5464 substrate-binding region of ABC-type glycine betaine transporter; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SPTR: substrate-binding region of ABC-type glycine betaine transporter; PFAM: substrate binding domain of ABC-type glycine betaine transporter; glycine betaine ABC transporter substrate-binding protein 945863..946765 Spirochaeta smaragdinae DSM 11293 9488978 YP_003802626.1 CDS Spirs_0898 NC_014364.1 946917 948242 D COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: btu:BT0142 outer membrane protein TolC; PFAM: outer membrane efflux protein; SPTR: Outer membrane protein TolC; PFAM: Outer membrane efflux protein; outer membrane efflux protein 946917..948242 Spirochaeta smaragdinae DSM 11293 9488979 YP_003802627.1 CDS Spirs_0899 NC_014364.1 948247 949248 D COGs: COG0845 membrane-fusion protein; InterPro IPR006143; KEGG: bre:BRE_143 membrane fusion protein; SPTR: membrane fusion protein; TIGRFAM: efflux transporter RND family, MFP subunit; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit 948247..949248 Spirochaeta smaragdinae DSM 11293 9488980 YP_003802628.1 CDS Spirs_0900 NC_014364.1 949249 952392 D COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: bbu:BB0140 acriflavine resistance protein (AcrB); PFAM: acriflavin resistance protein; SPTR: Acriflavine resistance protein; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: heavy metal efflux pump (cobalt-zinc-cadmium); acriflavin resistance protein 949249..952392 Spirochaeta smaragdinae DSM 11293 9488981 YP_003802629.1 CDS Spirs_0901 NC_014364.1 952389 952682 D KEGG: bbz:BbuZS7_0139 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 952389..952682 Spirochaeta smaragdinae DSM 11293 9488982 YP_003802630.1 CDS Spirs_0902 NC_014364.1 952795 954882 R COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006380:IPR006937:IPR006379:IPR006378; KEGG: ote:Oter_3274 HAD family hydrolase; PFAM: sucrose-6F-phosphate phosphohydrolase; neutral invertase; SPTR: HAD-superfamily hydrolase, subfamily IIB; TIGRFAM: sucrose-phosphate phosphatase subfamily; HAD-superfamily hydrolase, subfamily IIB; PFAM: Plant neutral invertase; sucrose-6F-phosphate phosphohydrolase; TIGRFAM: sucrose-6F-phosphate phosphohydrolase; sucrose-phosphate phosphatase subfamily; HAD-superfamily hydrolase, subfamily IIB; sucrose-phosphate phosphatase subfamily complement(952795..954882) Spirochaeta smaragdinae DSM 11293 9488983 YP_003802631.1 CDS Spirs_0903 NC_014364.1 954879 956165 R COGs: COG0438 glycosyltransferase; InterPro IPR000368:IPR001296; KEGG: atc:AGR_C_1178 hypothetical protein; PFAM: glycosyl transferase group 1; sucrose synthase; SPTR: glycosyltransferase; PFAM: sucrose synthase; glycosyl transferases group 1; group 1 glycosyl transferase complement(954879..956165) Spirochaeta smaragdinae DSM 11293 9488984 YP_003802632.1 CDS Spirs_0904 NC_014364.1 956319 957221 R InterPro IPR000326; KEGG: tpd:Teth39_1543 phosphoesterase, PA-phosphatase related; PFAM: phosphoesterase PA-phosphatase related; SMART: phosphoesterase PA-phosphatase related; SPTR: membrane-associated phospholipid phosphatase; PFAM: PAP2 superfamily; PA-phosphatase-like phosphoesterase complement(956319..957221) Spirochaeta smaragdinae DSM 11293 9488985 YP_003802633.1 CDS Spirs_0905 NC_014364.1 957275 958189 D KEGG: ccv:CCV52592_0166 transcriptional regulator, LuxR family protein; SPTR: LuxR family transcriptional regulator protein; hypothetical protein 957275..958189 Spirochaeta smaragdinae DSM 11293 9488986 YP_003802634.1 CDS Spirs_0906 NC_014364.1 958208 959107 R COGs: COG0010 arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR020855:IPR005924:IPR005925; KEGG: dat:HRM2_01390 SpeB; PFAM: arginase/agmatinase/formiminoglutamase; SPTR: SpeB; TIGRFAM: agmatinase; PFAM: arginase family; TIGRFAM: agmatinase; agmatinase complement(958208..959107) Spirochaeta smaragdinae DSM 11293 9488987 YP_003802635.1 CDS Spirs_0907 NC_014364.1 959104 960267 R COGs: COG0019 diaminopimelate decarboxylase; InterPro IPR000183:IPR005730; KEGG: cce:Ccel_1129 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: carboxynorspermidine decarboxylase; TIGRFAM: carboxynorspermidine decarboxylase; PFAM: pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase; carboxynorspermidine decarboxylase complement(959104..960267) Spirochaeta smaragdinae DSM 11293 9488988 YP_003802636.1 CDS Spirs_0908 NC_014364.1 960243 961424 R COGs: COG1748 saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: ttu:TERTU_1609 saccharopine dehydrogenase; PFAM: saccharopine dehydrogenase; SPTR: saccharopine dehydrogenase; PFAM: saccharopine dehydrogenase; saccharopine dehydrogenase complement(960243..961424) Spirochaeta smaragdinae DSM 11293 9488989 YP_003802637.1 CDS Spirs_0909 NC_014364.1 961500 962129 R COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: cbe:Cbei_0680 O-methyltransferase family protein; PFAM: O-methyltransferase family 3; SPTR: O-methyltransferase family 3; PFAM: O-methyltransferase; O-methyltransferase family 3 complement(961500..962129) Spirochaeta smaragdinae DSM 11293 9488990 YP_003802638.1 CDS Spirs_0910 NC_014364.1 962256 963257 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: rmr:Rmar_0279 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 962256..963257 Spirochaeta smaragdinae DSM 11293 9488991 YP_003802639.1 CDS Spirs_0911 NC_014364.1 963279 964721 D COGs: COG0366 glycosidase; InterPro IPR006047:IPR006589:IPR016377; KEGG: dol:Dole_0651 sucrose phosphorylase; PFAM: alpha amylase catalytic region; PRIAM: sucrose phosphorylase; SMART: alpha amylase catalytic sub domain; SPTR: sucrose phosphorylase; PFAM: alpha amylase, catalytic domain; sucrose phosphorylase 963279..964721 Spirochaeta smaragdinae DSM 11293 9488992 YP_003802640.1 CDS Spirs_0912 NC_014364.1 964718 966784 R KEGG: tde:TDE1580 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR03545; hypothetical protein complement(964718..966784) Spirochaeta smaragdinae DSM 11293 9488993 YP_003802641.1 CDS Spirs_0913 NC_014364.1 966781 967320 R InterPro IPR019935; KEGG: tde:TDE1581 hypothetical protein; SPTR: membrane protein, ; TIGRFAM: conserved hypothetical protein TIGR03546; hypothetical protein complement(966781..967320) Spirochaeta smaragdinae DSM 11293 9488994 YP_003802642.1 CDS Spirs_0914 NC_014364.1 967423 968517 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: pdi:BDI_3186 gluconate kinase; PFAM: PfkB domain protein; SPTR: PfkB; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(967423..968517) Spirochaeta smaragdinae DSM 11293 9488995 YP_003802643.1 CDS Spirs_0915 NC_014364.1 968514 969170 R COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: nml:Namu_1527 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase subfamily; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase complement(968514..969170) Spirochaeta smaragdinae DSM 11293 9488996 YP_003802644.1 CDS Spirs_0916 NC_014364.1 969372 970151 D COGs: COG1414 transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: dda:Dd703_2055 IclR family transcriptional regulator; PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: Pectin degradation repressor protein KdgR; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator 969372..970151 Spirochaeta smaragdinae DSM 11293 9488997 YP_003802645.1 CDS Spirs_0917 NC_014364.1 970306 971163 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: ddf:DEFDS_2028 amino acid ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein 970306..971163 Spirochaeta smaragdinae DSM 11293 9488998 YP_003802646.1 CDS Spirs_0918 NC_014364.1 971274 971927 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: mmz:MmarC7_1570 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 971274..971927 Spirochaeta smaragdinae DSM 11293 9488999 YP_003802647.1 CDS Spirs_0919 NC_014364.1 971932 972570 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: ljo:LJ0756 glutamine ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 971932..972570 Spirochaeta smaragdinae DSM 11293 9489000 YP_003802648.1 CDS Spirs_0920 NC_014364.1 972586 973326 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: cac:CAC3618 ABC-type polar amino acid transporter, ATPase component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 972586..973326 Spirochaeta smaragdinae DSM 11293 9489001 YP_003802649.1 CDS Spirs_0921 NC_014364.1 973357 974457 D COGs: COG0075 serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: tte:TTE2614 serine-pyruvate aminotransferase/aspartate aminotransferase; PFAM: aminotransferase class V; SPTR: serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; PFAM: Aminotransferase class-V; class V aminotransferase 973357..974457 Spirochaeta smaragdinae DSM 11293 9489002 YP_003802650.1 CDS Spirs_0922 NC_014364.1 974454 975221 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: rso:RSp0947 gluconate 5-dehydrogenase oxidoreductase protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Probable gluconate 5-dehydrogenase oxidoreductase protein; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 974454..975221 Spirochaeta smaragdinae DSM 11293 9489003 YP_003802651.1 CDS Spirs_0923 NC_014364.1 975254 976276 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR000716; KEGG: bmq:BMQ_2819 zinc-binding dehydrogenase family protein; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 975254..976276 Spirochaeta smaragdinae DSM 11293 9489004 YP_003802652.1 CDS Spirs_0924 NC_014364.1 976273 977226 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: tpd:Teth39_1970 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 976273..977226 Spirochaeta smaragdinae DSM 11293 9489005 YP_003802653.1 CDS Spirs_0925 NC_014364.1 977369 978421 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: rrs:RoseRS_2559 alanine racemase; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: alanine racemase; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 977369..978421 Spirochaeta smaragdinae DSM 11293 9489006 YP_003802654.1 CDS Spirs_0926 NC_014364.1 978413 980809 R COGs: COG1501 alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: hor:Hore_19090 alpha-glucosidase; PFAM: glycoside hydrolase family 31; SPTR: alpha-glucosidase; PFAM: glycosyl hydrolases family 31; glycoside hydrolase family protein complement(978413..980809) Spirochaeta smaragdinae DSM 11293 9489007 YP_003802655.1 CDS Spirs_0927 NC_014364.1 980924 981553 D COGs: COG2755 lysophospholipase L1 and related esterase; KEGG: ret:RHE_CH01936 arylesterase protein; SPTR: Probable arylesterase protein; PFAM: GDSL-like Lipase/acylhydrolase; arylesterase protein 980924..981553 Spirochaeta smaragdinae DSM 11293 9489008 YP_003802656.1 CDS Spirs_0928 NC_014364.1 981736 981960 R KEGG: cpo:COPRO5265_1332 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(981736..981960) Spirochaeta smaragdinae DSM 11293 9489009 YP_003802657.1 CDS Spirs_0929 NC_014364.1 982074 984668 D COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR018368:IPR001270:IPR004176:IPR003959:IPR 013093:IPR019489:IPR003593:IPR017730; KEGG: bhy:BHWA1_00583 ATP-dependent Clp protease ATP-binding subunit ClpB; PFAM: ATPase AAA; Clp domain protein; ATPase AAA; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATP-dependent chaperone protein ClpB; TIGRFAM: ATP-dependent chaperone ClpB; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB; ATP-dependent chaperone ClpB 982074..984668 Spirochaeta smaragdinae DSM 11293 9489010 YP_003802658.1 CDS Spirs_0930 NC_014364.1 984665 985690 R KEGG: gur:Gura_4404 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(984665..985690) Spirochaeta smaragdinae DSM 11293 9489011 YP_003802659.1 CDS Spirs_0931 NC_014364.1 985687 986322 R COGs: COG2068 Uncharacterized MobA-related protein; KEGG: cro:ROD_33901 hypothetical protein; SPTR: uncharacterized protein; molybdenum cofactor cytidylyltransferase complement(985687..986322) Spirochaeta smaragdinae DSM 11293 9489012 YP_003802660.1 CDS Spirs_0932 NC_014364.1 986399 986776 D KEGG: dps:DP0380 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 986399..986776 Spirochaeta smaragdinae DSM 11293 9489013 YP_003802661.1 CDS Spirs_0933 NC_014364.1 986966 988246 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_3246 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 986966..988246 Spirochaeta smaragdinae DSM 11293 9489014 YP_003802662.1 CDS Spirs_0934 NC_014364.1 988292 989179 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hor:Hore_13130 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; manually curated; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 988292..989179 Spirochaeta smaragdinae DSM 11293 9489015 YP_003802663.1 CDS Spirs_0935 NC_014364.1 989189 990040 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: cce:Ccel_3244 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 989189..990040 Spirochaeta smaragdinae DSM 11293 9489016 YP_003802664.1 CDS Spirs_0936 NC_014364.1 990146 991255 D KEGG: tde:TDE0194 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 990146..991255 Spirochaeta smaragdinae DSM 11293 9489017 YP_003802665.1 CDS Spirs_0937 NC_014364.1 991239 991682 R InterPro IPR013026; KEGG: tde:TDE2147 lipoprotein; SPTR: Lipoprotein; hypothetical protein complement(991239..991682) Spirochaeta smaragdinae DSM 11293 9489018 YP_003802666.1 CDS Spirs_0938 NC_014364.1 991705 991998 R KEGG: lbf:LBF_2743 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(991705..991998) Spirochaeta smaragdinae DSM 11293 9489019 YP_003802667.1 CDS Spirs_0939 NC_014364.1 992123 992854 D COGs: COG1811 Uncharacterized membrane protein Na+ channel or pump; InterPro IPR007563; KEGG: bhy:BHWA1_02425 hypothetical protein; PFAM: protein of unknown function DUF554; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF554); hypothetical protein 992123..992854 Spirochaeta smaragdinae DSM 11293 9489020 YP_003802668.1 CDS Spirs_0940 NC_014364.1 992878 995448 R COGs: COG0058 glucan phosphorylase; InterPro IPR000811:IPR011833; KEGG: ade:Adeh_0864 glycogen/starch/alpha-glucan phosphorylase; PFAM: glycosyl transferase family 35; SPTR: phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylase; PFAM: carbohydrate phosphorylase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; glycogen/starch/alpha-glucan phosphorylases; glycogen/starch/alpha-glucan phosphorylase complement(992878..995448) Spirochaeta smaragdinae DSM 11293 9489021 YP_003802669.1 CDS Spirs_0941 NC_014364.1 995475 997022 R COGs: COG3604 transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR002078:IPR003018:IPR002197:IPR003593:IPR 010113:IPR020441; KEGG: rpa:RPA1374 sigma-54 dependent, vanadium nitrogenase transcriptional regulator, VnfA; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; ATPase AAA; SPTR: Sigma-54 dependent, Vanadium nitrogenase transcriptional regulator, VnfA; TIGRFAM: Nif-specific regulatory protein; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein; Fis family transcriptional regulator complement(995475..997022) Spirochaeta smaragdinae DSM 11293 9489022 YP_003802670.1 CDS Spirs_0942 NC_014364.1 997514 997690 D InterPro IPR018264:IPR001705; KEGG: tde:TDE2428 50S ribosomal protein L33; PFAM: ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: ribosomal protein L33; manually curated; PFAM: ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type; 50S ribosomal protein L33 997514..997690 Spirochaeta smaragdinae DSM 11293 9489024 YP_003802671.1 CDS Spirs_0943 NC_014364.1 997805 997984 D InterPro IPR001901:IPR005807; KEGG: tpp:TPASS_0235 preprotein translocase subunit SecE; PFAM: protein secE/sec61-gamma protein; SPTR: protein translocase subunit secE/sec61 gamma; TIGRFAM: preprotein translocase, SecE subunit; PFAM: SecE/Sec61-subunit gammas of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial; preprotein translocase subunit SecE 997805..997984 Spirochaeta smaragdinae DSM 11293 9489026 YP_003802672.1 CDS Spirs_0944 NC_014364.1 998064 998618 D COGs: COG0250 transcription antiterminator; InterPro IPR015869:IPR006645:IPR005824:IPR001062; KEGG: tde:TDE2426 transcription antitermination protein NusG; PFAM: NGN domain protein; KOW domain protein; SMART: NGN domain protein; KOW domain protein; SPTR: transcription antitermination protein nusG; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG; NusG antitermination factor 998064..998618 Spirochaeta smaragdinae DSM 11293 9489027 YP_003802673.1 CDS Spirs_0945 NC_014364.1 998698 999129 D COGs: COG0080 ribosomal protein L11; InterProIPR020785:IPR020784:IPR020783:IPR000911:IPR 006519; KEGG: tde:TDE2425 50S ribosomal protein L11; PFAM: ribosomal protein L11-like; SMART: ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: ribosomal protein L11; PFAM: ribosomal protein L11, RNA binding domain; ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11; 50S ribosomal protein L11 998698..999129 Spirochaeta smaragdinae DSM 11293 9489028 YP_003802674.1 CDS Spirs_0946 NC_014364.1 999129 999812 D COGs: COG0081 ribosomal protein L1; InterPro IPR002143:IPR005878; KEGG: btu:BT0392 50S ribosomal protein L1; PFAM: ribosomal protein L1; SPTR: ribosomal protein L1; TIGRFAM: ribosomal protein L1; PFAM: ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast; 50S ribosomal protein L1 999129..999812 Spirochaeta smaragdinae DSM 11293 9489029 YP_003802675.1 CDS Spirs_0947 NC_014364.1 999814 1000350 D COGs: COG0244 ribosomal protein L10; InterPro IPR002363:IPR001790; KEGG: tde:TDE2423 50S ribosomal protein L10; PFAM: ribosomal protein L10; SPTR: 50S ribosomal protein L10; PFAM: ribosomal protein L10; 50S ribosomal protein L10 999814..1000350 Spirochaeta smaragdinae DSM 11293 9489030 YP_003802676.1 CDS Spirs_0948 NC_014364.1 1000463 1000852 D COGs: COG0222 ribosomal protein L7/L12; InterPro IPR013823:IPR000206; KEGG: dal:Dalk_1922 ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: ribosomal protein L7/L12; PFAM: ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12; 50S ribosomal protein L7/L12 1000463..1000852 Spirochaeta smaragdinae DSM 11293 9489031 YP_003802677.1 CDS Spirs_0949 NC_014364.1 1000983 1004483 D COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterProIPR007121:IPR007644:IPR007642:IPR007645:IPR 019462:IPR007120:IPR007641:IPR010243; KEGG: tde:TDE2421 DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2 domain 6; RNA polymerase Rpb2 domain 3; RNA polymerase subunit beta; RNA polymerase Rpb2 domain 2; DNA-directed RNA polymerase subunit beta, external 1 domain; RNA polymerase Rpb2 domain 7; SPTR: DNA-directed RNA polymerase; TIGRFAM: DNA-directed RNA polymerase subunit beta; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase subunit beta external 1 domain; RNA polymerase subunit beta; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase subunit beta; DNA-directed RNA polymerase subunit beta 1000983..1004483 Spirochaeta smaragdinae DSM 11293 9489032 YP_003802678.1 CDS Spirs_0950 NC_014364.1 1004498 1008775 D COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; InterProIPR007080:IPR000722:IPR007066:IPR007083:IPR 007081:IPR006592:IPR012754:IPR012756; KEGG: tde:TDE2420 DNA-directed RNA polymerase subunit beta'; PFAM: RNA polymerase Rpb1 domain 1; RNA polymerase subunit alpha; RNA polymerase Rpb1 domain 3; RNA polymerase Rpb1 domain 4; RNA polymerase Rpb1 domain 5; SMART: RNA polymerase I subunit A domain protein; SPTR: DNA-directed RNA polymerase; TIGRFAM: DNA-directed RNA polymerase, beta' subunit; DNA-directed RNA polymerase, beta'' subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb1, domain 3; TIGRFAM: DNA-directed RNA polymerase, beta'' subunit; DNA-directed RNA polymerase, beta' subunit, predominant form; DNA-directed RNA polymerase subunit beta' 1004498..1008775 Spirochaeta smaragdinae DSM 11293 9489033 YP_003802679.1 CDS Spirs_0951 NC_014364.1 1008845 1009219 D COGs: COG0048 ribosomal protein S12; InterPro IPR006032:IPR005679; KEGG: tpp:TPASS_0243 30S ribosomal protein S12; PFAM: ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: ribosomal protein S12; PFAM: ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle; 30S ribosomal protein S12 1008845..1009219 Spirochaeta smaragdinae DSM 11293 9489034 YP_003802680.1 CDS Spirs_0952 NC_014364.1 1009231 1009701 D COGs: COG0049 ribosomal protein S7; InterPro IPR000235:IPR005717; KEGG: tpp:TPASS_0244 30S ribosomal protein S7; PFAM: ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: ribosomal protein S7; PFAM: ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle; 30S ribosomal protein S7 1009231..1009701 Spirochaeta smaragdinae DSM 11293 9489035 YP_003802681.1 CDS Spirs_0953 NC_014364.1 1010057 1011247 D COGs: COG0050 GTPase - translation elongation factors; InterProIPR000795:IPR004161:IPR004160:IPR004541:IPR 005225; KEGG: tde:TDE0765 elongation factor Tu; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor Tu domain protein; SPTR: Elongation factor Tu; TIGRFAM: translation elongation factor Tu; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU; translation elongation factor Tu 1010057..1011247 Spirochaeta smaragdinae DSM 11293 9489036 YP_003802682.1 CDS Spirs_0954 NC_014364.1 1011309 1011617 D COGs: COG0051 ribosomal protein S10; InterPro IPR018268:IPR001848:IPR005731; KEGG: tde:TDE0766 30S ribosomal protein S10; PFAM: ribosomal protein S10; SPTR: ribosomal protein S10; TIGRFAM: ribosomal protein S10; PFAM: ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle; 30S ribosomal protein S10 1011309..1011617 Spirochaeta smaragdinae DSM 11293 9489037 YP_003802683.1 CDS Spirs_0955 NC_014364.1 1011650 1012270 D COGs: COG0087 ribosomal protein L3; InterPro IPR019926:IPR000597:IPR019927; KEGG: bhr:BH0478 50S ribosomal protein L3; PFAM: ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3; PFAM: ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial; 50S ribosomal protein L3 1011650..1012270 Spirochaeta smaragdinae DSM 11293 9489038 YP_003802684.1 CDS Spirs_0956 NC_014364.1 1012280 1012909 D COGs: COG0088 ribosomal protein L4; InterPro IPR002136; KEGG: tde:TDE0768 50S ribosomal protein L4; PFAM: ribosomal protein L4/L1e; SPTR: ribosomal protein, L4/L1 family; PFAM: ribosomal protein L4/L1 family; 50S ribosomal protein L4/L1e 1012280..1012909 Spirochaeta smaragdinae DSM 11293 9489039 YP_003802685.1 CDS Spirs_0957 NC_014364.1 1012920 1013222 D COGs: COG0089 ribosomal protein L23; InterPro IPR001014:IPR013025; KEGG: rxy:Rxyl_2153 50S ribosomal protein L23P; PFAM: ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; PFAM: ribosomal protein L23; 50S ribosomal protein L25/L23 1012920..1013222 Spirochaeta smaragdinae DSM 11293 9489040 YP_003802686.1 CDS Spirs_0958 NC_014364.1 1013238 1014062 D COGs: COG0090 ribosomal protein L2; InterPro IPR002171:IPR005880; KEGG: bhr:BH0481 50S ribosomal protein L2; PFAM: ribosomal protein L2; SPTR: 50S ribosomal protein L2P; TIGRFAM: ribosomal protein L2; PFAM: ribosomal proteins L2, RNA binding domain; ribosomal proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar; 50S ribosomal protein L2 1013238..1014062 Spirochaeta smaragdinae DSM 11293 9489041 YP_003802687.1 CDS Spirs_0959 NC_014364.1 1014073 1014354 D COGs: COG0185 ribosomal protein S19; InterPro IPR002222:IPR005732; KEGG: tpp:TPASS_0193 30S ribosomal protein S19; PFAM: ribosomal protein S19/S15; SPTR: ribosomal protein S19; TIGRFAM: ribosomal protein S19; PFAM: ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle; 30S ribosomal protein S19 1014073..1014354 Spirochaeta smaragdinae DSM 11293 9489042 YP_003802688.1 CDS Spirs_0960 NC_014364.1 1014363 1014725 D COGs: COG0091 ribosomal protein L22; InterPro IPR018260:IPR001063:IPR005727; KEGG: tde:TDE0772 50S ribosomal protein L22; PFAM: ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: ribosomal protein L22; PFAM: ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type; 50S ribosomal protein L22 1014363..1014725 Spirochaeta smaragdinae DSM 11293 9489043 YP_003802689.1 CDS Spirs_0961 NC_014364.1 1014726 1015427 D COGs: COG0092 ribosomal protein S3; InterProIPR018280:IPR008282:IPR004044:IPR001351:IPR 004087:IPR005704; KEGG: tde:TDE0773 30S ribosomal protein S3; PFAM: ribosomal protein S3- domain protein; KH type 2 domain protein; ribosomal protein S3 domain; SMART: KH domain protein; SPTR: ribosomal protein S3; TIGRFAM: ribosomal protein S3; PFAM: KH domain; ribosomal protein S3, C-terminal domain; ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type; 30S ribosomal protein S3 1014726..1015427 Spirochaeta smaragdinae DSM 11293 9489044 YP_003802690.1 CDS Spirs_0962 NC_014364.1 1015434 1015850 D COGs: COG0197 ribosomal protein L16/L10E; InterPro IPR020798:IPR016180:IPR000114; KEGG: cwo:Cwoe_1347 ribosomal protein L16; PFAM: ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: ribosomal protein L16; PFAM: ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle; 50S ribosomal protein L16 1015434..1015850 Spirochaeta smaragdinae DSM 11293 9489045 YP_003802691.1 CDS Spirs_0963 NC_014364.1 1015854 1016057 D InterPro IPR001854; KEGG: bhr:BH0486 50S ribosomal protein L29; PFAM: ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: ribosomal L29 protein; TIGRFAM: ribosomal protein L29; 50S ribosomal protein L29 1015854..1016057 Spirochaeta smaragdinae DSM 11293 9489046 YP_003802692.1 CDS Spirs_0964 NC_014364.1 1016081 1016332 D COGs: COG0186 ribosomal protein S17; InterPro IPR019979:IPR000266:IPR019984; KEGG: cch:Cag_1842 30S ribosomal protein S17; PFAM: ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; PFAM: ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17; 30S ribosomal protein S17 1016081..1016332 Spirochaeta smaragdinae DSM 11293 9489047 YP_003802693.1 CDS Spirs_0965 NC_014364.1 1016356 1016724 D COGs: COG0093 ribosomal protein L14; InterPro IPR019972:IPR000218:IPR005745; KEGG: tde:TDE0777 50S ribosomal protein L14; PFAM: ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: ribosomal protein L14; PFAM: ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle; 50S ribosomal protein L14 1016356..1016724 Spirochaeta smaragdinae DSM 11293 9489048 YP_003802694.1 CDS Spirs_0966 NC_014364.1 1016735 1017052 D COGs: COG0198 ribosomal protein L24; InterPro IPR005825:IPR005824:IPR003256; KEGG: coc:Coch_1158 ribosomal protein L24; PFAM: KOW domain protein; SMART: KOW domain protein; SPTR: ribosomal protein L24; TIGRFAM: ribosomal protein L24; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle; 50S ribosomal protein L24 1016735..1017052 Spirochaeta smaragdinae DSM 11293 9489049 YP_003802695.1 CDS Spirs_0967 NC_014364.1 1017052 1017606 D COGs: COG0094 ribosomal protein L5; InterPro IPR002132; KEGG: tde:TDE0779 50S ribosomal protein L5; PFAM: ribosomal protein L5; SPTR: 50S ribosomal protein L5; PFAM: ribosomal L5P family C-terminus; ribosomal protein L5; 50S ribosomal protein L5 1017052..1017606 Spirochaeta smaragdinae DSM 11293 9489050 YP_003802696.1 CDS Spirs_0968 NC_014364.1 1017619 1017804 D COGs: COG0199 ribosomal protein S14; InterPro IPR018271:IPR001209; KEGG: baf:BAPKO_0519 30S ribosomal protein S14; PFAM: ribosomal protein S14; SPTR: 30S ribosomal protein S14 type Z; manually curated; PFAM: ribosomal protein S14p/S29e; 30S ribosomal protein S14 1017619..1017804 Spirochaeta smaragdinae DSM 11293 9489051 YP_003802697.1 CDS Spirs_0969 NC_014364.1 1017814 1018212 D COGs: COG0096 ribosomal protein S8; InterPro IPR000630; KEGG: tde:TDE0781 30S ribosomal protein S8; PFAM: ribosomal protein S8; SPTR: ribosomal protein S8; PFAM: ribosomal protein S8; 30S ribosomal protein S8 1017814..1018212 Spirochaeta smaragdinae DSM 11293 9489052 YP_003802698.1 CDS Spirs_0970 NC_014364.1 1018228 1018767 D COGs: COG0097 ribosomal protein L6P/L9E; InterPro IPR002358:IPR020040:IPR019906:IPR000702; KEGG: bre:BRE_499 50S ribosomal protein L6; PFAM: ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: ribosomal protein L6; PFAM: ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type; 50S ribosomal protein L6 1018228..1018767 Spirochaeta smaragdinae DSM 11293 9489053 YP_003802699.1 CDS Spirs_0971 NC_014364.1 1018784 1019152 D COGs: COG0256 ribosomal protein L18; InterPro IPR005484:IPR004389; KEGG: tde:TDE0783 50S ribosomal protein L18; PFAM: ribosomal protein L18P/L5E; SPTR: 50S ribosomal protein L18; TIGRFAM: ribosomal protein L18; PFAM: ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type; 50S ribosomal protein L18 1018784..1019152 Spirochaeta smaragdinae DSM 11293 9489054 YP_003802700.1 CDS Spirs_0972 NC_014364.1 1019162 1019656 D COGs: COG0098 ribosomal protein S5; InterPro IPR018192:IPR013810:IPR005324:IPR005712; KEGG: tde:TDE0784 30S ribosomal protein S5; PFAM: ribosomal protein S5 ; ribosomal protein S5 domain protein; SPTR: 30S ribosomal protein S5; TIGRFAM: ribosomal protein S5; PFAM: ribosomal protein S5, C-terminal domain; ribosomal protein S5, N-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type; 30S ribosomal protein S5 1019162..1019656 Spirochaeta smaragdinae DSM 11293 9489055 YP_003802701.1 CDS Spirs_0973 NC_014364.1 1019661 1019855 D COGs: COG1841 ribosomal protein L30/L7E; InterPro IPR018038:IPR000517:IPR005996; KEGG: sss:SSUSC84_0087 50S ribosomal protein L30; PFAM: ribosomal protein L30; SPTR: 50S ribosomal protein L30; TIGRFAM: ribosomal protein L30; PFAM: ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle; 50S ribosomal protein L30 1019661..1019855 Spirochaeta smaragdinae DSM 11293 9489056 YP_003802702.1 CDS Spirs_0974 NC_014364.1 1019861 1020322 D COGs: COG0200 ribosomal protein L15; InterPro IPR001196:IPR005749; KEGG: tde:TDE0786 50S ribosomal protein L15; PFAM: ribosomal protein L15; SPTR: ribosomal protein L15; TIGRFAM: ribosomal protein L15; PFAM: ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle; 50S ribosomal protein L15 1019861..1020322 Spirochaeta smaragdinae DSM 11293 9489057 YP_003802703.1 CDS Spirs_0975 NC_014364.1 1020312 1021634 D COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR019825:IPR002208; KEGG: tde:TDE0787 preprotein translocase subunit SecY; PFAM: SecY protein; SPTR: Preprotein translocase, SecY subunit; TIGRFAM: preprotein translocase, SecY subunit; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit; preprotein translocase subunit SecY 1020312..1021634 Spirochaeta smaragdinae DSM 11293 9489058 YP_003802704.1 CDS Spirs_0976 NC_014364.1 1021648 1021761 D InterPro IPR000473; KEGG: tde:TDE0788 50S ribosomal protein L36; PFAM: ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: ribosomal protein L36; manually curated; PFAM: ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type; 50S ribosomal protein L36 1021648..1021761 Spirochaeta smaragdinae DSM 11293 9489059 YP_003802705.1 CDS Spirs_0977 NC_014364.1 1021774 1022139 D COGs: COG0099 ribosomal protein S13; InterPro IPR018269:IPR001892:IPR019980; KEGG: bre:BRE_506 30S ribosomal protein S13; PFAM: ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: 30S ribosomal protein S13; PFAM: ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13; 30S ribosomal protein S13 1021774..1022139 Spirochaeta smaragdinae DSM 11293 9489060 YP_003802706.1 CDS Spirs_0978 NC_014364.1 1022157 1022540 D COGs: COG0100 ribosomal protein S11; InterPro IPR018102:IPR001971:IPR019981; KEGG: tpp:TPASS_0211 30S ribosomal protein S11; PFAM: ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; PFAM: ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11; 30S ribosomal protein S11 1022157..1022540 Spirochaeta smaragdinae DSM 11293 9489061 YP_003802707.1 CDS Spirs_0979 NC_014364.1 1022556 1023191 D COGs: COG0522 ribosomal protein S4 and related protein; InterPro IPR018079:IPR001912:IPR002942:IPR005709; KEGG: geo:Geob_3600 30S ribosomal protein S4; PFAM: RNA-binding S4 domain protein; ribosomal protein S4; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type; 30S ribosomal protein S4 1022556..1023191 Spirochaeta smaragdinae DSM 11293 9489062 YP_003802708.1 CDS Spirs_0980 NC_014364.1 1023200 1024255 D COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR011261:IPR011262:IPR011260:IPR011773:IPR 011263; KEGG: tde:TDE0791 DNA-directed RNA polymerase subunit alpha; PFAM: RNA polymerase subunit alpha domain protein; RNA polymerase insert; RNA polymerase dimerisation; SMART: RNA polymerase RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase, subunit alpha; TIGRFAM: DNA-directed RNA polymerase, subunit alpha; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; DNA-directed RNA polymerase subunit alpha 1023200..1024255 Spirochaeta smaragdinae DSM 11293 9489063 YP_003802709.1 CDS Spirs_0981 NC_014364.1 1024245 1024739 D COGs: COG0203 ribosomal protein L17; InterPro IPR000456; KEGG: tde:TDE0792 50S ribosomal protein L17; PFAM: ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: ribosomal protein L17; PFAM: ribosomal protein L17; TIGRFAM: ribosomal protein L17; 50S ribosomal protein L17 1024245..1024739 Spirochaeta smaragdinae DSM 11293 9489064 YP_003802710.1 CDS Spirs_0982 NC_014364.1 1024927 1026666 D COGs: COG1966 carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: dat:HRM2_21730 CstA; PFAM: carbon starvation protein CstA; SPTR: CstA; PFAM: carbon starvation protein CstA; carbon starvation protein CstA 1024927..1026666 Spirochaeta smaragdinae DSM 11293 9489065 YP_003802711.1 CDS Spirs_0983 NC_014364.1 1026730 1027179 D KEGG: dat:HRM2_21740 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1026730..1027179 Spirochaeta smaragdinae DSM 11293 9489066 YP_003802712.1 CDS Spirs_0984 NC_014364.1 1027169 1027453 D KEGG: tko:TK0993 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1027169..1027453 Spirochaeta smaragdinae DSM 11293 9489067 YP_003802713.1 CDS Spirs_0985 NC_014364.1 1027453 1028334 D COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: tko:TK0994 arsenical pump-driving ATPase; PFAM: Anion-transporting ATPase; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenical pump-driving ATPase; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA); Arsenite-transporting ATPase 1027453..1028334 Spirochaeta smaragdinae DSM 11293 9489068 YP_003802714.1 CDS Spirs_0986 NC_014364.1 1028656 1030944 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: dhd:Dhaf_2112 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1028656..1030944 Spirochaeta smaragdinae DSM 11293 9489069 YP_003802715.1 CDS Spirs_0987 NC_014364.1 1030996 1032282 R COGs: COG0281 Malic enzyme; InterPro IPR015884:IPR012301:IPR012302; KEGG: bhy:BHWA1_01613 malate dehydrogenase; PFAM: malic protein NAD-binding; malic protein domain protein; SPTR: malate dehydrogenase; PFAM: Malic enzyme, NAD binding domain; Malic enzyme, N-terminal domain; malic protein NAD-binding protein complement(1030996..1032282) Spirochaeta smaragdinae DSM 11293 9489070 YP_003802716.1 CDS Spirs_0988 NC_014364.1 1032319 1033566 R COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: dat:HRM2_30760 hypothetical protein; PFAM: protein of unknown function DUF2088; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088); hypothetical protein complement(1032319..1033566) Spirochaeta smaragdinae DSM 11293 9489071 YP_003802717.1 CDS Spirs_0989 NC_014364.1 1033557 1034816 R COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR015911:IPR001576; KEGG: kol:Kole_0995 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: phosphoglycerate kinase; SPTR: phosphoglycerate kinase; PFAM: phosphoglycerate kinase; phosphoglycerate kinase complement(1033557..1034816) Spirochaeta smaragdinae DSM 11293 9489072 YP_003802718.1 CDS Spirs_0990 NC_014364.1 1034893 1035915 R COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR000846:IPR020829:IPR006436:IPR020831; KEGG: kol:Kole_0996 glyceraldehyde-3-phosphate dehydrogenaseI; PFAM: glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; dihydrodipicolinate reductase; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)(+)) (phosphorylating); SPTR: glyceraldehyde-3-phosphate dehydrogenase, type II; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenaseI; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenaseI; glyceraldehyde-3-phosphate dehydrogenaseI complement(1034893..1035915) Spirochaeta smaragdinae DSM 11293 9489073 YP_003802719.1 CDS Spirs_0991 NC_014364.1 1036829 1038142 D COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR004680; KEGG: bpf:BpOF4_16100 hypothetical protein; PFAM: citrate transporter; SPTR: citrate transporter; PFAM: citrate transporter; citrate transporter 1036829..1038142 Spirochaeta smaragdinae DSM 11293 9489074 YP_003802720.1 CDS Spirs_0992 NC_014364.1 1038183 1039148 D COGs: COG2513 PEP phosphonomutase; KEGG: rle:RL4464 lyase/mutase; SPTR: lyase/mutase; lyase/mutase 1038183..1039148 Spirochaeta smaragdinae DSM 11293 9489075 YP_003802721.1 CDS Spirs_0993 NC_014364.1 1039413 1040093 D COGs: COG1802 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: str:Sterm_0694 transcriptional regulator, GntR family; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 1039413..1040093 Spirochaeta smaragdinae DSM 11293 9489076 YP_003802722.1 CDS Spirs_0994 NC_014364.1 1040291 1041274 D COGs: COG1052 lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: sna:Snas_1558 phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 1040291..1041274 Spirochaeta smaragdinae DSM 11293 9489077 YP_003802723.1 CDS Spirs_0995 NC_014364.1 1041284 1042792 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018483:IPR018484:IPR018485; KEGG: kpu:KP1_1111 L-xylulose kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 1041284..1042792 Spirochaeta smaragdinae DSM 11293 9489078 YP_003802724.1 CDS Spirs_0996 NC_014364.1 1042834 1043532 D COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303:IPR004661; KEGG: gyc:GYMC61_2736 L-ribulose-5-phosphate 4-epimerase; PFAM: class II aldolase/adducin family protein; SPTR: uncharacterized protein; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; PFAM: class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; L-ribulose-5-phosphate 4-epimerase 1042834..1043532 Spirochaeta smaragdinae DSM 11293 9489079 YP_003802725.1 CDS Spirs_0997 NC_014364.1 1043536 1044555 D KEGG: cpf:CPF_0647 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1043536..1044555 Spirochaeta smaragdinae DSM 11293 9489080 YP_003802726.1 CDS Spirs_0998 NC_014364.1 1044557 1045414 D COGs: COG3623 L-xylulose-5-phosphate 3-epimerase; InterPro IPR000408:IPR012307:IPR004560; KEGG: cpf:CPF_0649 L-xylulose 5-phosphate 3-epimerase; PFAM: Xylose isomerase domain protein TIM barrel; PRIAM: L-ribulose-5-phosphate 3-epimerase; SPTR: uncharacterized protein; TIGRFAM: hexulose-6-phosphate isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: hexulose-6-phosphate isomerase; hexulose-6-phosphate isomerase 1044557..1045414 Spirochaeta smaragdinae DSM 11293 9489081 YP_003802727.1 CDS Spirs_0999 NC_014364.1 1045623 1046273 R InterPro IPR013216; KEGG: drm:Dred_0699 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain; type 11 methyltransferase complement(1045623..1046273) Spirochaeta smaragdinae DSM 11293 9489082 YP_003802728.1 CDS Spirs_1001 NC_014364.1 1046761 1047810 D COGs: COG1363 cellulase M and related protein; InterPro IPR008007; KEGG: kol:Kole_0588 peptidase M42 family protein; PFAM: peptidase M42 family protein; SPTR: peptidase M42 family protein; PFAM: M42 glutamyl aminopeptidase; peptidase M42 family protein 1046761..1047810 Spirochaeta smaragdinae DSM 11293 9489084 YP_003802729.1 CDS Spirs_1002 NC_014364.1 1047829 1048671 D InterPro IPR000620; KEGG: cpi:Cpin_7126 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Conserved hypothetical transmembrane protein; PFAM: EamA-like transporter family; hypothetical protein 1047829..1048671 Spirochaeta smaragdinae DSM 11293 9489085 YP_003802730.1 CDS Spirs_1003 NC_014364.1 1048688 1049653 D COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: mta:Moth_0235 hypothetical protein; PFAM: protein of unknown function DUF161; protein of unknown function DUF2179; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179); hypothetical protein 1048688..1049653 Spirochaeta smaragdinae DSM 11293 9489086 YP_003802731.1 CDS Spirs_1004 NC_014364.1 1049788 1050726 R COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transporter (osmoprotectant binding protein); InterPro IPR007210; KEGG: pmo:Pmob_1128 substrate-binding region of ABC-type glycine betaine transporter; PFAM: substrate-binding region of ABC-type glycine betaine transporter; SPTR: substrate-binding region of ABC-type glycine betaine transporter; PFAM: substrate binding domain of ABC-type glycine betaine transporter; glycine betaine ABC transporter substrate-binding protein complement(1049788..1050726) Spirochaeta smaragdinae DSM 11293 9489087 YP_003802732.1 CDS Spirs_1005 NC_014364.1 1050777 1051424 R COGs: COG1174 ABC-type proline/glycine betaine transport systems permease; InterPro IPR000515; KEGG: pmo:Pmob_1127 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1050777..1051424) Spirochaeta smaragdinae DSM 11293 9489088 YP_003802733.1 CDS Spirs_1006 NC_014364.1 1051424 1052524 R COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterProIPR017871:IPR003439:IPR000644:IPR003593:IPR 005892; KEGG: pmo:Pmob_1126 glycine betaine/L-proline ABC transporter ATPase subunit; PFAM: ABC transporter; CBS domain containing protein; SMART: ATPase AAA; CBS domain containing protein; SPTR: glycine betaine/L-proline ABC transporter ATPase; TIGRFAM: glycine betaine/L-proline ABC transporter ATPase; PFAM: ABC transporter; CBS domain; TIGRFAM: glycine betaine/L-proline transport ATP binding subunit; glycine betaine/L-proline ABC transporter ATPase subunit complement(1051424..1052524) Spirochaeta smaragdinae DSM 11293 9489089 YP_003802734.1 CDS Spirs_1007 NC_014364.1 1052521 1053156 R COGs: COG1174 ABC-type proline/glycine betaine transport systems permease; InterPro IPR000515; KEGG: pmo:Pmob_1125 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1052521..1053156) Spirochaeta smaragdinae DSM 11293 9489090 YP_003802735.1 CDS Spirs_1008 NC_014364.1 1053520 1053996 D COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: sde:Sde_1188 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcriptional regulator, MarR family; PFAM: MarR family; MarR family transcriptional regulator 1053520..1053996 Spirochaeta smaragdinae DSM 11293 9489091 YP_003802736.1 CDS Spirs_1009 NC_014364.1 1054211 1055329 D COGs: COG2309 leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: afl:Aflv_0455 aminopeptidase; PFAM: peptidase M29 aminopeptidase II; SPTR: Aminopeptidase; PFAM: Thermophilic metalloprotease (M29); peptidase M29 aminopeptidase II 1054211..1055329 Spirochaeta smaragdinae DSM 11293 9489092 YP_003802737.1 CDS Spirs_1010 NC_014364.1 1055369 1056088 R COGs: COG3689 membrane protein; KEGG: dae:Dtox_0337 protein of unknown function DUF1980; SPTR: uncharacterized protein; membrane protein complement(1055369..1056088) Spirochaeta smaragdinae DSM 11293 9489093 YP_003802738.1 CDS Spirs_1011 NC_014364.1 1056085 1057008 R COGs: COG0701 permease; InterPro IPR005524; KEGG: cno:NT01CX_2389 permease family protein; PFAM: permease; SPTR: Permease; PFAM: Predicted permease; permease complement(1056085..1057008) Spirochaeta smaragdinae DSM 11293 9489094 YP_003802739.1 CDS Spirs_1012 NC_014364.1 1057016 1057510 R COGs: COG2062 phosphohistidine phosphatase SixA; InterPro IPR013078; KEGG: tfu:Tfu_0135 hypothetical protein; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase, ; PFAM: phosphoglycerate mutase family; phosphohistidine phosphatase SixA complement(1057016..1057510) Spirochaeta smaragdinae DSM 11293 9489095 YP_003802740.1 CDS Spirs_1013 NC_014364.1 1057507 1058427 R COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054; KEGG: fal:FRAAL0057 adenylate cyclase; SPTR: adenylate cyclase; adenylate/guanylate cyclase complement(1057507..1058427) Spirochaeta smaragdinae DSM 11293 9489096 YP_003802741.1 CDS Spirs_1014 NC_014364.1 1058540 1059277 R COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: dds:Ddes_1512 TonB family protein; SPTR: TonB family protein; TIGRFAM: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TonB family protein complement(1058540..1059277) Spirochaeta smaragdinae DSM 11293 9489097 YP_003802742.1 CDS Spirs_1015 NC_014364.1 1059332 1061314 R COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: sat:SYN_01425 outer membrane B12 receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor; SPTR: Outer membrane B12 receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TonB-dependent receptor plug complement(1059332..1061314) Spirochaeta smaragdinae DSM 11293 9489098 YP_003802743.1 CDS Spirs_1016 NC_014364.1 1061604 1062782 R COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: gym:GYMC10_1404 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II; class I and II aminotransferase complement(1061604..1062782) Spirochaeta smaragdinae DSM 11293 9489099 YP_003802744.1 CDS Spirs_1017 NC_014364.1 1062910 1064160 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: rrs:RoseRS_3086 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 1062910..1064160 Spirochaeta smaragdinae DSM 11293 9489100 YP_003802745.1 CDS Spirs_1018 NC_014364.1 1064160 1065194 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: aco:Amico_0335 transporter permease; PFAM: transporter permease; SPTR: transport system permease; PFAM: FecCD transport family; transporter permease 1064160..1065194 Spirochaeta smaragdinae DSM 11293 9489101 YP_003802746.1 CDS Spirs_1019 NC_014364.1 1065194 1066243 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR003439:IPR003593; KEGG: rrs:RoseRS_3089 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 1065194..1066243 Spirochaeta smaragdinae DSM 11293 9489102 YP_003802747.1 CDS Spirs_1020 NC_014364.1 1066296 1066673 D COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR019897:IPR006175:IPR006056; KEGG: dsa:Desal_3497 endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; SPTR: L-PSP (MRNA) endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; endoribonuclease L-PSP 1066296..1066673 Spirochaeta smaragdinae DSM 11293 9489103 YP_003802748.1 CDS Spirs_1021 NC_014364.1 1066663 1068099 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR010964; KEGG: hor:Hore_08190 Xaa-His dipeptidase; PFAM: peptidase M20; SPTR: Xaa-His dipeptidase; TIGRFAM: dipeptidase; PFAM: peptidase family M20/M25/M40; TIGRFAM: dipeptidase; dipeptidase 1066663..1068099 Spirochaeta smaragdinae DSM 11293 9489104 YP_003802749.1 CDS Spirs_1022 NC_014364.1 1068231 1069184 D COGs: COG0549 carbamate kinase; InterPro IPR001048:IPR003964; KEGG: ton:TON_1502 carbamate kinase-like carbamoyl phosphate synthetase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: carbamate kinase; SPTR: carbamate kinase; TIGRFAM: carbamate kinase; PFAM: Amino acid kinase family; TIGRFAM: carbamate kinase; carbamate kinase 1068231..1069184 Spirochaeta smaragdinae DSM 11293 9489105 YP_003802750.1 CDS Spirs_1023 NC_014364.1 1069346 1070632 D COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: geo:Geob_2854 hypothetical protein; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II; class I and II aminotransferase 1069346..1070632 Spirochaeta smaragdinae DSM 11293 9489106 YP_003802751.1 CDS Spirs_1024 NC_014364.1 1070639 1070995 D COGs: COG2005 N-terminal domain of molybdenum-binding protein; InterPro IPR000847; KEGG: chy:CHY_0619 molybdenum transporter; PFAM: regulatory protein LysR; SPTR: N-terminal domain of molybdenum-binding protein; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: ModE molybdate transport repressor domain; ModE family transcriptional regulator 1070639..1070995 Spirochaeta smaragdinae DSM 11293 9489107 YP_003802752.1 CDS Spirs_1025 NC_014364.1 1071023 1071787 R COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: dfe:Dfer_2129 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: transcriptional regulator, DeoR family; manually curated; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator complement(1071023..1071787) Spirochaeta smaragdinae DSM 11293 9489108 YP_003802753.1 CDS Spirs_1026 NC_014364.1 1071793 1073274 R COGs: COG0554 glycerol kinase; InterPro IPR018484:IPR018485; KEGG: dfe:Dfer_2143 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; carbohydrate kinase FGGY complement(1071793..1073274) Spirochaeta smaragdinae DSM 11293 9489109 YP_003802754.1 CDS Spirs_1027 NC_014364.1 1073274 1074236 R COGs: COG3958 transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: kpu:KP1_1545 transketolase C-terminal subunit; PFAM: transketolase; transketolase domain protein; SPTR: transketolase C-terminal subunit; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain; transketolase complement(1073274..1074236) Spirochaeta smaragdinae DSM 11293 9489110 YP_003802755.1 CDS Spirs_1028 NC_014364.1 1074238 1075065 R COGs: COG3959 transketolase N-terminal subunit; InterPro IPR005474; KEGG: asu:Asuc_0171 transketolase domain-containing protein; PFAM: transketolase; SPTR: transketolase; PFAM: transketolase, thiamine diphosphate binding domain; transketolase complement(1074238..1075065) Spirochaeta smaragdinae DSM 11293 9489111 YP_003802756.1 CDS Spirs_1029 NC_014364.1 1075258 1076214 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: rec:RHECIAT_PC0000969 probable ribose ABC transporter substrate-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Probable ABC transporter sugar-binding protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1075258..1076214 Spirochaeta smaragdinae DSM 11293 9489112 YP_003802757.1 CDS Spirs_1030 NC_014364.1 1076292 1076966 D COGs: COG5618 periplasmic lipoprotein; InterPro IPR014582; KEGG: rec:RHECIAT_PC0000970 hypothetical protein; PFAM: periplasmic lipoprotein; SPTR: uncharacterized protein; PFAM: Predicted periplasmic lipoprotein (DUF2291); periplasmic lipoprotein 1076292..1076966 Spirochaeta smaragdinae DSM 11293 9489113 YP_003802758.1 CDS Spirs_1031 NC_014364.1 1076969 1078522 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: mlo:mll7012 ribose ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ATP-binding D-ribose transporter (ABC superfamily, atp_bind); PFAM: ABC transporter; ABC transporter 1076969..1078522 Spirochaeta smaragdinae DSM 11293 9489114 YP_003802759.1 CDS Spirs_1032 NC_014364.1 1078538 1079620 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: sme:SM_b20352 sugar ABC transporter permease; PFAM: inner-membrane translocator; SPTR: ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1078538..1079620 Spirochaeta smaragdinae DSM 11293 9489115 YP_003802760.1 CDS Spirs_1033 NC_014364.1 1079617 1081041 D COGs: COG2407 L-fucose isomerase and related protein; InterPro IPR012889:IPR015888; KEGG: bvu:BVU_0356 hypothetical protein; PFAM: L-fucose isomerase-like-like; L-fucose isomerase _2 domain protein; SPTR: uncharacterized protein; PFAM: L-fucose isomerase, C-terminal domain; L-fucose isomerase 1079617..1081041 Spirochaeta smaragdinae DSM 11293 9489116 YP_003802761.1 CDS Spirs_1034 NC_014364.1 1081066 1081500 D COGs: COG4154 Fucose dissimilation pathway protein FucU; InterPro IPR007721; KEGG: pjd:Pjdr2_1349 RbsD or FucU transport; PFAM: RbsD or FucU transport; SPTR: Fucose operon protein FucU; PFAM: RbsD / FucU transporter family; RbsD or FucU transporter 1081066..1081500 Spirochaeta smaragdinae DSM 11293 9489117 YP_003802762.1 CDS Spirs_1035 NC_014364.1 1081519 1082538 R COGs: COG2502 Asparagine synthetase A; InterPro IPR000183:IPR004618:IPR006195; KEGG: bvu:BVU_4147 asparagine synthetase AsnA; PFAM: aspartate--ammonia ligase; PRIAM: aspartate--ammonia ligase; SPTR: aspartate-ammonia ligase; TIGRFAM: aspartate/ammonia ligase; manually curated; PFAM: aspartate-ammonia ligase; TIGRFAM: aspartate--ammonia ligase, AsnA-type; aspartate/ammonia ligase complement(1081519..1082538) Spirochaeta smaragdinae DSM 11293 9489118 YP_003802763.1 CDS Spirs_1036 NC_014364.1 1082679 1083095 D COGs: COG2703 hemerythrin; InterPro IPR016131:IPR012312:IPR012827; KEGG: gsu:GSU0402 hemerythrin family protein; PFAM: hemerythrin HHE cation binding domain protein; SPTR: hemerythrin family protein; TIGRFAM: hemerythrin-like metal-binding protein; PFAM: hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain; hemerythrin-like metal-binding protein 1082679..1083095 Spirochaeta smaragdinae DSM 11293 9489119 YP_003802764.1 CDS Spirs_1037 NC_014364.1 1083184 1083813 D COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; InterPro IPR010916; KEGG: tye:THEYE_A1664 metal dependent hydrolase; SPTR: metal dependent hydrolase; metal dependent hydrolase 1083184..1083813 Spirochaeta smaragdinae DSM 11293 9489120 YP_003802765.1 CDS Spirs_1038 NC_014364.1 1083803 1084183 R InterPro IPR010652; KEGG: hypothetical protein; PFAM: protein of unknown function DUF1232; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1232); hypothetical protein complement(1083803..1084183) Spirochaeta smaragdinae DSM 11293 9489121 YP_003802766.1 CDS Spirs_1039 NC_014364.1 1084194 1085465 R COGs: COG0017 aspartyl/asparaginyl-tRNA synthetase; InterProIPR004365:IPR004364:IPR006195:IPR004523:IPR 002312; KEGG: cpf:CPF_0770 aspartyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; SPTR: aspartyl-tRNA synthetase; TIGRFAM: aspartyl-tRNA synthetase; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, archaeal type; aspartyl-tRNA synthetase complement(1084194..1085465) Spirochaeta smaragdinae DSM 11293 9489122 YP_003802767.1 CDS Spirs_1040 NC_014364.1 1085462 1086889 R COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterProIPR017958:IPR006075:IPR006107:IPR018027:IPR 004413; KEGG: aae:aq_461 aspartyl/glutamyl-tRNA amidotransferase subunit B; PFAM: GatB region; GatB central domain protein; Asn/Gln amidotransferase; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase subunit beta; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase subunit beta; glutamyl-tRNA(Gln) amidotransferase subunit B complement(1085462..1086889) Spirochaeta smaragdinae DSM 11293 9489123 YP_003802768.1 CDS Spirs_1041 NC_014364.1 1086893 1088296 R COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; InterPro IPR020556:IPR000120:IPR004412; KEGG: ttr:Tter_0058 glutamyl-tRNA(Gln) amidotransferase, subunit alpha; PFAM: amidase; SPTR: glutamyl-tRNA(Gln) amidotransferase, subunit alpha; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase, subunit alpha; PFAM: amidase; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase, subunit alpha; glutamyl-tRNA(Gln) amidotransferase subunit A complement(1086893..1088296) Spirochaeta smaragdinae DSM 11293 9489124 YP_003802769.1 CDS Spirs_1042 NC_014364.1 1088405 1088683 R COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; InterPro IPR003837; KEGG: nth:Nther_0463 glutamyl-tRNA(Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; SPTR: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: glutamyl-tRNA(Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: glutamyl-tRNA(Gln) and/or aspartyl-tRNA(Asn) amidotransferase subunit C; glutamyl-tRNA(Gln) amidotransferase subunit C complement(1088405..1088683) Spirochaeta smaragdinae DSM 11293 9489125 YP_003802770.1 CDS Spirs_1043 NC_014364.1 1088835 1090433 R COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR006146:IPR004843:IPR008334:IPR006179; KEGG: taf:THA_358 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; PFAM: 5'-nucleotidase domain protein; metallophosphoesterase; PRIAM: 5'-nucleotidase; SPTR: protein UshA; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase; 5'-nucleotidase complement(1088835..1090433) Spirochaeta smaragdinae DSM 11293 9489126 YP_003802771.1 CDS Spirs_1044 NC_014364.1 1090506 1090925 D KEGG: dsa:Desal_1002 translation initiation factor IF-2; SPTR: translation initiation factor IF-2; hypothetical protein 1090506..1090925 Spirochaeta smaragdinae DSM 11293 9489127 YP_003802772.1 CDS Spirs_1045 NC_014364.1 1090909 1092525 R COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR017937:IPR004137:IPR010048; KEGG: dap:Dacet_1289 hybrid cluster protein; PFAM: Prismane; SPTR: Hybrid cluster protein; TIGRFAM: hybrid cluster protein; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: hydroxylamine reductase; hybrid cluster protein complement(1090909..1092525) Spirochaeta smaragdinae DSM 11293 9489128 YP_003802773.1 CDS Spirs_1046 NC_014364.1 1092631 1093329 D COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR012318; KEGG: kol:Kole_1156 transcriptional regulator, Crp/Fnr family; PFAM: cyclic nucleotide-binding; SPTR: transcriptional regulator, Crp/Fnr family; manually curated; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator 1092631..1093329 Spirochaeta smaragdinae DSM 11293 9489129 YP_003802774.1 CDS Spirs_1047 NC_014364.1 1093326 1094534 D COGs: COG0787 alanine racemase; InterPro IPR001608:IPR011079:IPR000821; KEGG: mta:Moth_2167 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: alanine racemase; SPTR: alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase, C-terminal domain; alanine racemase, N-terminal domain; TIGRFAM: alanine racemase; alanine racemase 1093326..1094534 Spirochaeta smaragdinae DSM 11293 9489130 YP_003802775.1 CDS Spirs_1048 NC_014364.1 1094531 1095412 R COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002227:IPR006115:IPR006183; KEGG: dsa:Desal_3747 6-phosphogluconate dehydrogenase NAD-binding; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 6-phosphogluconate dehydrogenase NAD-binding; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 2-hydroxy-3-oxopropionate reductase complement(1094531..1095412) Spirochaeta smaragdinae DSM 11293 9489131 YP_003802776.1 CDS Spirs_1049 NC_014364.1 1095379 1096779 R COGs: COG4452 Inner membrane protein involved in colicin E2 resistance; InterPro IPR010364; KEGG: dal:Dalk_1578 hypothetical protein; PFAM: inner membrane protein CreD; SPTR: Inner membrane CreD family protein; PFAM: Inner membrane protein CreD; inner membrane protein CreD complement(1095379..1096779) Spirochaeta smaragdinae DSM 11293 9489132 YP_003802777.1 CDS Spirs_1050 NC_014364.1 1096936 1097646 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: jan:Jann_0536 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 1096936..1097646 Spirochaeta smaragdinae DSM 11293 9489133 YP_003802778.1 CDS Spirs_1051 NC_014364.1 1097643 1099238 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: scl:sce4877 two-component histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 1097643..1099238 Spirochaeta smaragdinae DSM 11293 9489134 YP_003802779.1 CDS Spirs_1052 NC_014364.1 1099303 1100505 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR018114:IPR013108; KEGG: mta:Moth_0460 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(1099303..1100505) Spirochaeta smaragdinae DSM 11293 9489135 YP_003802780.1 CDS Spirs_1053 NC_014364.1 1100581 1101576 D COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: gau:GAU_0026 lipoprotein; PFAM: basic membrane lipoprotein; SPTR: uncharacterized protein; PFAM: Basic membrane protein; basic membrane lipoprotein 1100581..1101576 Spirochaeta smaragdinae DSM 11293 9489136 YP_003802781.1 CDS Spirs_1054 NC_014364.1 1101640 1102716 D COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: tit:Thit_0432 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 1101640..1102716 Spirochaeta smaragdinae DSM 11293 9489137 YP_003802782.1 CDS Spirs_1055 NC_014364.1 1102716 1103639 D COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: rxy:Rxyl_0158 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 1102716..1103639 Spirochaeta smaragdinae DSM 11293 9489138 YP_003802783.1 CDS Spirs_1056 NC_014364.1 1103655 1105172 D COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR000834:IPR017871:IPR003439:IPR003593; KEGG: ctc:CTC00370 sugar transport ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: Sugar transport ATP-binding protein; PFAM: ABC transporter; ABC transporter 1103655..1105172 Spirochaeta smaragdinae DSM 11293 9489139 YP_003802784.1 CDS Spirs_1057 NC_014364.1 1105186 1105920 D COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: str:Sterm_0942 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator 1105186..1105920 Spirochaeta smaragdinae DSM 11293 9489140 YP_003802785.1 CDS Spirs_1058 NC_014364.1 1105929 1108181 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: cdf:CD2087 xanthine dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: xanthine dehydrogenase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein 1105929..1108181 Spirochaeta smaragdinae DSM 11293 9489141 YP_003802786.1 CDS Spirs_1059 NC_014364.1 1108169 1110913 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterProIPR006058:IPR001041:IPR002888:IPR000674:IPR 008274; KEGG: cdf:CD2087 xanthine dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; [2Fe-2S]-binding domain protein; ferredoxin; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: xanthine dehydrogenase; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; 2Fe-2S iron-sulfur cluster binding domain; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein 1108169..1110913 Spirochaeta smaragdinae DSM 11293 9489142 YP_003802787.1 CDS Spirs_1060 NC_014364.1 1110926 1112161 D COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: cbi:CLJ_B1493 sensor histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: histidine kinase-like ATPase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 1110926..1112161 Spirochaeta smaragdinae DSM 11293 9489143 YP_003802788.1 CDS Spirs_1061 NC_014364.1 1112165 1112842 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ana:all4635 two-component response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 1112165..1112842 Spirochaeta smaragdinae DSM 11293 9489144 YP_003802789.1 CDS Spirs_1062 NC_014364.1 1113012 1114409 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: kol:Kole_0811 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1113012..1114409 Spirochaeta smaragdinae DSM 11293 9489145 YP_003802790.1 CDS Spirs_1063 NC_014364.1 1114533 1115426 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pmo:Pmob_0073 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1114533..1115426 Spirochaeta smaragdinae DSM 11293 9489146 YP_003802791.1 CDS Spirs_1064 NC_014364.1 1115420 1116382 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: pmo:Pmob_0072 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1115420..1116382 Spirochaeta smaragdinae DSM 11293 9489147 YP_003802792.1 CDS Spirs_1065 NC_014364.1 1116439 1117467 R COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: ace:Acel_1715 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; manually curated; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(1116439..1117467) Spirochaeta smaragdinae DSM 11293 9489148 YP_003802793.1 CDS Spirs_1066 NC_014364.1 1117622 1119118 D COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: drt:Dret_1767 sodium:neurotransmitter symporter; PFAM: sodium:neurotransmitter symporter; SPTR: transporter; PFAM: Sodium:neurotransmitter symporter family; sodium:neurotransmitter symporter 1117622..1119118 Spirochaeta smaragdinae DSM 11293 9489149 YP_003802794.1 CDS Spirs_1067 NC_014364.1 1119128 1119229 D KEGG: drt:Dret_1766 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1119128..1119229 Spirochaeta smaragdinae DSM 11293 9489150 YP_003802795.1 CDS Spirs_1068 NC_014364.1 1119415 1120425 D COGs: COG2378 transcriptional regulator protein; KEGG: rca:Rcas_1009 regulatory protein, DeoR; SPTR: Regulatory protein, DeoR; PFAM: HTH domain; regulatory protein, DeoR 1119415..1120425 Spirochaeta smaragdinae DSM 11293 9489151 YP_003802796.1 CDS Spirs_1069 NC_014364.1 1120569 1122794 D COGs: COG1203 helicase; InterProIPR014021:IPR001650:IPR014001:IPR006483:IPR 006474; KEGG: dma:DMR_14350 hypothetical protein; SMART: DEAD-like helicase; SPTR: metal dependent phosphohydrolase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated HD domain protein; PFAM: DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated HD domain protein; CRISPR-associated helicase Cas3; CRISPR-associated helicase Cas3 1120569..1122794 Spirochaeta smaragdinae DSM 11293 9489152 YP_003802797.1 CDS Spirs_1070 NC_014364.1 1122804 1123466 D InterPro IPR010155:IPR013422; KEGG: xac:XAC3838 hypothetical protein; PFAM: CRISPR-associated protein CT1134; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, Dvulg subtype; CRISPR-associated protein Cas5, N-terminal domain; CRISPR-associated protein Cas5 family 1122804..1123466 Spirochaeta smaragdinae DSM 11293 9489153 YP_003802798.1 CDS Spirs_1071 NC_014364.1 1123463 1125235 D InterPro IPR010144; KEGG: dvu:DVUA0131 CRISPR-associated Csd1 family protein; PFAM: CRISPR-associated protein CT1133; SPTR: CRISPR-associated protein, CT1133 family; TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein, Csd1 family; CRISPR-associated protein, Csd1 family 1123463..1125235 Spirochaeta smaragdinae DSM 11293 9489154 YP_003802799.1 CDS Spirs_1072 NC_014364.1 1125235 1126101 D COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR006482:IPR013418; KEGG: msu:MS0986 hypothetical protein; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein, Csd2 family; TIGRFAM: CRISPR-associated protein, Csd2 family; CRISPR-associated protein, CT1132 family; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family; CRISPR-associated protein, Csd2 family 1125235..1126101 Spirochaeta smaragdinae DSM 11293 9489155 YP_003802800.1 CDS Spirs_1073 NC_014364.1 1126143 1126787 D COGs: COG1468 RecB family exonuclease; InterPro IPR013343; KEGG: dhd:Dhaf_2187 CRISPR-associated protein Cas4; PFAM: CRISPR-associated protein Cas4; SPTR: CRISPR-associated protein Cas4; TIGRFAM: CRISPR-associated protein Cas4; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4; CRISPR-associated protein Cas4 1126143..1126787 Spirochaeta smaragdinae DSM 11293 9489156 YP_003802801.1 CDS Spirs_1074 NC_014364.1 1126787 1127812 D COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR002729:IPR019856; KEGG: sat:SYN_02473 cytoplasmic protein; PFAM: protein of unknown function DUF48; SPTR: Hypothetical cytosolic protein; TIGRFAM: CRISPR-associated protein Cas1; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1, HMARI/TNEAP subtype; CRISPR-associated protein Cas1; CRISPR-associated protein Cas1, DVULG subtype; CRISPR-associated protein Cas1 1126787..1127812 Spirochaeta smaragdinae DSM 11293 9489157 YP_003802802.1 CDS Spirs_1075 NC_014364.1 1127824 1128117 D COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR003799; KEGG: pvi:Cvib_1306 CRISPR-associated Cas2 family protein; PFAM: protein of unknown function DUF196; SPTR: CRISPR-associated protein, Cas2 family; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated protein Cas2; CRISPR-associated protein Cas2 1127824..1128117 Spirochaeta smaragdinae DSM 11293 9489158 YP_003802803.1 CDS Spirs_1076 NC_014364.1 1134537 1135823 D COGs: COG4222 conserved hypothetical protein; KEGG: mmw:Mmwyl1_1224 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1134537..1135823 Spirochaeta smaragdinae DSM 11293 9489159 YP_003802804.1 CDS Spirs_1077 NC_014364.1 1135983 1136543 D COGs: COG2059 Chromate transporter ChrA; InterPro IPR003370; KEGG: afn:Acfer_1719 chromate transporter; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter; Chromate transporter 1135983..1136543 Spirochaeta smaragdinae DSM 11293 9489160 YP_003802805.1 CDS Spirs_1078 NC_014364.1 1136540 1137112 D COGs: COG2059 Chromate transporter ChrA; InterPro IPR003370; KEGG: cpr:CPR_2214 chromate transporter; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter; Chromate transporter 1136540..1137112 Spirochaeta smaragdinae DSM 11293 9489161 YP_003802806.1 CDS Spirs_1079 NC_014364.1 1137430 1138152 R KEGG: srm:SRM_00121 conserved hypothetical protein, secreted; SPTR: Vcbs; hypothetical protein complement(1137430..1138152) Spirochaeta smaragdinae DSM 11293 9489162 YP_003802807.1 CDS Spirs_1080 NC_014364.1 1138286 1138795 D KEGG: tex:Teth514_0473 metal dependent phosphohydrolase; SPTR: metal dependent phosphohydrolase; hypothetical protein 1138286..1138795 Spirochaeta smaragdinae DSM 11293 9489163 YP_003802808.1 CDS Spirs_1081 NC_014364.1 1138808 1139224 D KEGG: fal:FRAAL2843 high-affinity branched-chain amino acid transport ATP-binding protein; membrane protein; SPTR: High-affinity branched-chain amino acid transport ATP-binding protein; membrane protein; hypothetical protein 1138808..1139224 Spirochaeta smaragdinae DSM 11293 9489164 YP_003802809.1 CDS Spirs_1082 NC_014364.1 1139231 1139926 D KEGG: ssa:SSA_0844 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1139231..1139926 Spirochaeta smaragdinae DSM 11293 9489165 YP_003802810.1 CDS Spirs_1084 NC_014364.1 1141011 1141499 R KEGG: swo:Swol_2247 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1141011..1141499) Spirochaeta smaragdinae DSM 11293 9489167 YP_003802811.1 CDS Spirs_1085 NC_014364.1 1141492 1142622 R COGs: COG2856 Zn peptidase; InterPro IPR001387:IPR010359; KEGG: dae:Dtox_3877 helix-turn-helix domain protein; PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Helix-turn-helix domain protein; PFAM: Helix-turn-helix; Domain of unknown function (DUF955); hypothetical protein complement(1141492..1142622) Spirochaeta smaragdinae DSM 11293 9489168 YP_003802812.1 CDS Spirs_1086 NC_014364.1 1142726 1142830 D hypothetical protein 1142726..1142830 Spirochaeta smaragdinae DSM 11293 9489169 YP_003802813.1 CDS Spirs_1087 NC_014364.1 1142899 1143147 D KEGG: ppg:PputGB1_4162 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1142899..1143147 Spirochaeta smaragdinae DSM 11293 9489170 YP_003802814.1 CDS Spirs_1088 NC_014364.1 1143149 1143346 D SPTR: uncharacterized protein; hypothetical protein 1143149..1143346 Spirochaeta smaragdinae DSM 11293 9489171 YP_003802815.1 CDS Spirs_1089 NC_014364.1 1143933 1144916 R KEGG: lpf:lpl2135 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1143933..1144916) Spirochaeta smaragdinae DSM 11293 9489172 YP_003802816.1 CDS Spirs_1091 NC_014364.1 1146517 1148673 D COGs: COG3808 inorganic pyrophosphatase; InterPro IPR004131; KEGG: eel:EUBELI_20579 inorganic pyrophosphatase; PFAM: inorganic H pyrophosphatase; PRIAM: inorganic diphosphatase; SPTR: inorganic pyrophosphatase; TIGRFAM: V-type H(+)-translocating pyrophosphatase; PFAM: inorganic H+ pyrophosphatase; TIGRFAM: vacuolar-type H(+)-translocating pyrophosphatase; V-type H(+)-translocating pyrophosphatase 1146517..1148673 Spirochaeta smaragdinae DSM 11293 9489174 YP_003802817.1 CDS Spirs_1092 NC_014364.1 1148835 1149605 D KEGG: app:CAP2UW1_3692 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1148835..1149605 Spirochaeta smaragdinae DSM 11293 9489175 YP_003802818.1 CDS Spirs_1093 NC_014364.1 1149621 1150238 R COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: hth:HTH_0103 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: alpha-ribazole-5-phosphate phosphatase; PFAM: phosphoglycerate mutase family; phosphoglycerate mutase complement(1149621..1150238) Spirochaeta smaragdinae DSM 11293 9489176 YP_003802819.1 CDS Spirs_1094 NC_014364.1 1150261 1151022 R COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: mta:Moth_0608 GntR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator complement(1150261..1151022) Spirochaeta smaragdinae DSM 11293 9489177 YP_003802820.1 CDS Spirs_1095 NC_014364.1 1151186 1152379 D COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: aba:acid345_0665 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); SPTR: Sugar isomerase (SIS); PFAM: SIS domain; sugar isomerase (SIS) 1151186..1152379 Spirochaeta smaragdinae DSM 11293 9489178 YP_003802821.1 CDS Spirs_1096 NC_014364.1 1152379 1153710 D COGs: COG4573 tagatose 6-phosphate kinase; InterPro IPR013838:IPR012062; KEGG: bac:BamMC406_2512 D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: D-tagatose-bisphosphate aldolase class II accessory protein AgaZ; SPTR: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; PFAM: Tagatose 6 phosphate kinase; TIGRFAM: D-tagatose-bisphosphate aldolase, class II, non-catalytic subunit; D-tagatose-bisphosphate aldolase class II accessory protein AgaZ 1152379..1153710 Spirochaeta smaragdinae DSM 11293 9489179 YP_003802822.1 CDS Spirs_1097 NC_014364.1 1153700 1154611 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tex:Teth514_0396 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1153700..1154611 Spirochaeta smaragdinae DSM 11293 9489180 YP_003802823.1 CDS Spirs_1098 NC_014364.1 1154656 1155507 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: cai:Caci_2624 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1154656..1155507 Spirochaeta smaragdinae DSM 11293 9489181 YP_003802824.1 CDS Spirs_1099 NC_014364.1 1155559 1156845 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: rlg:Rleg_5365 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: sugar uptake ABC transporter periplasmic solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1155559..1156845 Spirochaeta smaragdinae DSM 11293 9489182 YP_003802825.1 CDS Spirs_1100 NC_014364.1 1156962 1157906 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611:IPR002139; KEGG: dfe:Dfer_1706 PfkB domain protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 1156962..1157906 Spirochaeta smaragdinae DSM 11293 9489183 YP_003802826.1 CDS Spirs_1101 NC_014364.1 1158019 1159719 D COGs: COG5002 Signal transduction histidine kinase; InterProIPR018771:IPR013767:IPR003661:IPR003594:IPR 005467:IPR000014:IPR004358; KEGG: pca:Pcar_1399 two component sensor histidine kinase; PFAM: transcriptional regulator, histidine kinase sensor-like; PAS fold domain protein; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Predicted histidine kinase sensor domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor signal transduction histidine kinase 1158019..1159719 Spirochaeta smaragdinae DSM 11293 9489184 YP_003802827.1 CDS Spirs_1102 NC_014364.1 1159756 1160400 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: pca:Pcar_0978 two component signal transduction response regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 1159756..1160400 Spirochaeta smaragdinae DSM 11293 9489185 YP_003802828.1 CDS Spirs_1103 NC_014364.1 1160550 1161050 D COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: dsy:DSY0864 hypothetical protein; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein 1160550..1161050 Spirochaeta smaragdinae DSM 11293 9489186 YP_003802829.1 CDS Spirs_1104 NC_014364.1 1161052 1163535 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: drm:Dred_1504 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: xanthine dehydrogenase, molybdenum binding subunit apoprotein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein 1161052..1163535 Spirochaeta smaragdinae DSM 11293 9489187 YP_003802830.1 CDS Spirs_1105 NC_014364.1 1163537 1164508 D COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR005107:IPR016166; KEGG: dps:DP1724 oxidoreductase (molybdopterin binding subunit); PFAM: molybdopterin dehydrogenase FAD-binding; CO dehydrogenase flavoprotein domain protein; SPTR: Probable oxidoreductase (Molybdopterin binding subunit); PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; molybdopterin dehydrogenase FAD-binding protein 1163537..1164508 Spirochaeta smaragdinae DSM 11293 9489188 YP_003802831.1 CDS Spirs_1106 NC_014364.1 1164578 1165663 D KEGG: ape:APE_1539.1 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1164578..1165663 Spirochaeta smaragdinae DSM 11293 9489189 YP_003802832.1 CDS Spirs_1107 NC_014364.1 1165682 1166482 D COGs: COG2086 electron transfer flavoprotein beta subunit; InterPro IPR014730:IPR012255; KEGG: tye:THEYE_A1636 electron transfer flavoprotein beta-subunit; PFAM: electron transfer flavoprotein alpha/beta-subunit; SPTR: electron transfer flavoprotein beta-subunit; PFAM: electron transfer flavoprotein domain; electron transfer flavoprotein alpha/beta-subunit 1165682..1166482 Spirochaeta smaragdinae DSM 11293 9489190 YP_003802833.1 CDS Spirs_1108 NC_014364.1 1166498 1167496 D COGs: COG2025 electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731:IPR001308; KEGG: tte:TTE0547 electron transfer flavoprotein subunit alpha; PFAM: electron transfer flavoprotein alpha/beta-subunit ; electron transfer flavoprotein subunit alpha; SPTR: electron transfer flavoprotein alpha-subunit; PFAM: electron transfer flavoprotein domain; electron transfer flavoprotein FAD-binding domain; electron transfer flavoprotein alpha/beta-subunit 1166498..1167496 Spirochaeta smaragdinae DSM 11293 9489191 YP_003802834.1 CDS Spirs_1109 NC_014364.1 1167537 1167842 D InterPro IPR013974; KEGG: gtn:GTNG_1859 altronate hydrolase N-terminus; PFAM: SAF domain protein; SPTR: altronate hydrolase N-terminus; PFAM: SAF domain; SAF domain-containing protein 1167537..1167842 Spirochaeta smaragdinae DSM 11293 9489192 YP_003802835.1 CDS Spirs_1110 NC_014364.1 1167844 1169004 D COGs: COG2721 altronate dehydratase; InterPro IPR007392; KEGG: chy:CHY_1256 UxaA family hydrolase; PFAM: D-galactarate dehydratase/altronate hydrolase domain protein; PRIAM: altronate dehydratase; SPTR: uncharacterized protein; PFAM: D-galactarate dehydratase / altronate hydrolase, C terminus; altronate dehydratase 1167844..1169004 Spirochaeta smaragdinae DSM 11293 9489193 YP_003802836.1 CDS Spirs_1111 NC_014364.1 1169017 1170303 R KEGG: bvu:BVU_2930 trimethylamine corrinoid protein 2; SPTR: uncharacterized protein; hypothetical protein complement(1169017..1170303) Spirochaeta smaragdinae DSM 11293 9489194 YP_003802837.1 CDS Spirs_1113 NC_014364.1 1170828 1171859 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR000843; KEGG: aba:acid345_0908 LacI family transcription regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; LacI family transcriptional regulator 1170828..1171859 Spirochaeta smaragdinae DSM 11293 9489196 YP_003802838.1 CDS Spirs_1114 NC_014364.1 1171865 1173085 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tit:Thit_1721 ROK family protein; PFAM: ROK family protein; SPTR: Predicted protein; PFAM: ROK family; ROK family protein complement(1171865..1173085) Spirochaeta smaragdinae DSM 11293 9489197 YP_003802839.1 CDS Spirs_1115 NC_014364.1 1173241 1174065 D COGs: COG4130 sugar epimerase; InterPro IPR012307; KEGG: pfs:PFLU2578 hypothetical protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase 1173241..1174065 Spirochaeta smaragdinae DSM 11293 9489198 YP_003802840.1 CDS Spirs_1116 NC_014364.1 1174145 1175155 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: cbe:Cbei_4547 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: inositol 2-dehydrogenase; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 1174145..1175155 Spirochaeta smaragdinae DSM 11293 9489199 YP_003802841.1 CDS Spirs_1117 NC_014364.1 1175221 1176186 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: ere:EUBREC_1144 ABC-type sugar transport system, periplasmic component; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ABC-type sugar transporter, periplasmic component; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1175221..1176186 Spirochaeta smaragdinae DSM 11293 9489200 YP_003802842.1 CDS Spirs_1118 NC_014364.1 1176291 1177781 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR015862:IPR003593; KEGG: str:Sterm_4010 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 1176291..1177781 Spirochaeta smaragdinae DSM 11293 9489201 YP_003802843.1 CDS Spirs_1119 NC_014364.1 1177801 1178841 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: str:Sterm_4009 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1177801..1178841 Spirochaeta smaragdinae DSM 11293 9489202 YP_003802844.1 CDS Spirs_1120 NC_014364.1 1178936 1180102 D COGs: COG1373 ATPase (AAA+ superfamily); KEGG: pgn:PGN_1018 hypothetical protein; SPTR: uncharacterized protein; manually curated; hypothetical protein 1178936..1180102 Spirochaeta smaragdinae DSM 11293 9489203 YP_003802845.1 CDS Spirs_1121 NC_014364.1 1180221 1181798 D InterPro IPR011703; KEGG: lbf:LBF_2615 MoxR-like ATPase; PFAM: ATPase AAA; SPTR: ATPase; PFAM: ATPase family associated with various cellular activities (AAA); ATPase AAA 1180221..1181798 Spirochaeta smaragdinae DSM 11293 9489204 YP_003802846.1 CDS Spirs_1122 NC_014364.1 1181780 1182694 D KEGG: hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1181780..1182694 Spirochaeta smaragdinae DSM 11293 9489205 YP_003802847.1 CDS Spirs_1123 NC_014364.1 1182691 1184427 D KEGG: lbf:LBF_2617 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1182691..1184427 Spirochaeta smaragdinae DSM 11293 9489206 YP_003802848.1 CDS Spirs_1124 NC_014364.1 1184424 1185038 D KEGG: lbf:LBF_2618 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1184424..1185038 Spirochaeta smaragdinae DSM 11293 9489207 YP_003802849.1 CDS Spirs_1125 NC_014364.1 1185025 1186374 D COGs: COG1541 Coenzyme F390 synthetase; KEGG: lbf:LBF_2619 phenylacetate--CoA ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme; Coenzyme F390 synthetase 1185025..1186374 Spirochaeta smaragdinae DSM 11293 9489208 YP_003802850.1 CDS Spirs_1126 NC_014364.1 1186371 1187366 D COGs: COG3172 ATPase/kinase involved in NAD metabolism; KEGG: hau:Haur_0514 NAD metabolism ATPase/kinase; SPTR: ATPase/kinase involved in NAD metabolism; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type; NAD metabolism ATPase/kinase 1186371..1187366 Spirochaeta smaragdinae DSM 11293 9489209 YP_003802851.1 CDS Spirs_1127 NC_014364.1 1187360 1188049 D COGs: COG3201 Nicotinamide mononucleotide transporter; InterPro IPR006419; KEGG: npu:Npun_F0632 nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; SPTR: Nicotinamide mononucleotide transporter PnuC; TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter; TIGRFAM: nicotinamide mononucleotide transporter PnuC; nicotinamide mononucleotide transporter PnuC 1187360..1188049 Spirochaeta smaragdinae DSM 11293 9489210 YP_003802852.1 CDS Spirs_1128 NC_014364.1 1188543 1189067 D InterPro IPR001226; KEGG: tde:TDE1177 flavodoxin family protein; SPTR: Flavodoxin family protein; flavodoxin family protein 1188543..1189067 Spirochaeta smaragdinae DSM 11293 9489211 YP_003802853.1 CDS Spirs_1129 NC_014364.1 1189094 1190074 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: str:Sterm_0583 transporter permease; PFAM: transporter permease; SPTR: transport system permease; PFAM: FecCD transport family; transporter permease 1189094..1190074 Spirochaeta smaragdinae DSM 11293 9489212 YP_003802854.1 CDS Spirs_1130 NC_014364.1 1190071 1190889 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR017871:IPR003439:IPR003593; KEGG: str:Sterm_0584 ABC transporter protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: hemic transport system ATP-binding protein hmuV; PFAM: ABC transporter; ABC transporter 1190071..1190889 Spirochaeta smaragdinae DSM 11293 9489213 YP_003802855.1 CDS Spirs_1131 NC_014364.1 1190879 1192153 D COGs: COG0635 coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: fnu:FN0771 oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM superfamily; radical SAM protein 1190879..1192153 Spirochaeta smaragdinae DSM 11293 9489214 YP_003802856.1 CDS Spirs_1132 NC_014364.1 1192205 1193179 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: fnu:FN0767 hemin-binding periplasmic protein HmuT precursor; PFAM: periplasmic binding protein; SPTR: Iron ABC transporter; PFAM: Periplasmic binding protein; periplasmic binding protein 1192205..1193179 Spirochaeta smaragdinae DSM 11293 9489215 YP_003802857.1 CDS Spirs_1133 NC_014364.1 1193190 1193885 D COGs: COG0811 biopolymertransporter; InterPro IPR002898; KEGG: sbn:Sbal195_4371 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel 1193190..1193885 Spirochaeta smaragdinae DSM 11293 9489216 YP_003802858.1 CDS Spirs_1134 NC_014364.1 1193885 1194286 D COGs: COG0848 biopolymertransporter; InterPro IPR003400; KEGG: psa:PST_1711 TonB system transporter; PFAM: Biopolymer transporter ExbD/TolR; SPTR: biopolymertransporter ExbD/TolR family; PFAM: biopolymertransporter ExbD/TolR; biopolymertransporter ExbD/TolR 1193885..1194286 Spirochaeta smaragdinae DSM 11293 9489217 YP_003802859.1 CDS Spirs_1135 NC_014364.1 1194255 1195037 D COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR003538:IPR006260; KEGG: azl:AZL_007860 protein; PFAM: Gram-negative tonB protein; SPTR: TonB family protein; TIGRFAM: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TonB family protein 1194255..1195037 Spirochaeta smaragdinae DSM 11293 9489218 YP_003802860.1 CDS Spirs_1136 NC_014364.1 1195053 1197047 D COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: lbj:LBJ_4163 TonB-dependant outer membrane receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent outer membrane receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TonB-dependent receptor 1195053..1197047 Spirochaeta smaragdinae DSM 11293 9489219 YP_003802861.1 CDS Spirs_1137 NC_014364.1 1197166 1198218 D KEGG: cpi:Cpin_7218 hypothetical protein; SPTR: lipoprotein; hypothetical protein 1197166..1198218 Spirochaeta smaragdinae DSM 11293 9489220 YP_003802862.1 CDS Spirs_1138 NC_014364.1 1198413 1199231 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: azl:AZL_e03380 D-mannonate oxidoreductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: D-mannonate oxidoreductase; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(1198413..1199231) Spirochaeta smaragdinae DSM 11293 9489221 YP_003802863.1 CDS Spirs_1139 NC_014364.1 1199252 1199824 R KEGG: bhy:BHWA1_01194 hypothetical protein; SPTR: uncharacterized protein; PFAM: Predicted periplasmic protein (DUF2271); hypothetical protein complement(1199252..1199824) Spirochaeta smaragdinae DSM 11293 9489222 YP_003802864.1 CDS Spirs_1140 NC_014364.1 1199854 1200594 R COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: aoe:Clos_2137 sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; SPTR: Sec-independent protein translocase, TatC subunit; TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC; Sec-independent protein translocase subunit TatC complement(1199854..1200594) Spirochaeta smaragdinae DSM 11293 9489223 YP_003802865.1 CDS Spirs_1141 NC_014364.1 1200655 1200915 R COGs: COG1826 Sec-independent protein secretion pathway components; InterPro IPR003369:IPR006312:IPR003998; KEGG: swo:Swol_1443 sec-independent protein secretion pathway components-like protein; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase TatA; TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family; twin-arginine translocation protein, TatA/E family subunit complement(1200655..1200915) Spirochaeta smaragdinae DSM 11293 9489224 YP_003802866.1 CDS Spirs_1142 NC_014364.1 1200935 1201192 R InterPro IPR003369:IPR006312:IPR003998; KEGG: aoe:Clos_1101 twin arginine translocase protein A; PFAM: sec-independent translocation protein mttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog; TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family; twin-arginine translocation protein, TatA/E family subunit complement(1200935..1201192) Spirochaeta smaragdinae DSM 11293 9489225 YP_003802867.1 CDS Spirs_1143 NC_014364.1 1201232 1201798 R KEGG: aoe:Clos_2145 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1201232..1201798) Spirochaeta smaragdinae DSM 11293 9489226 YP_003802868.1 CDS Spirs_1144 NC_014364.1 1201914 1204013 R COGs: COG2414 aldehyde:ferredoxin oxidoreductase; InterPro IPR013983:IPR001203; KEGG: nth:Nther_2279 oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase ; aldehyde ferredoxin oxidoreductase; PRIAM: aldehyde ferredoxin oxidoreductase; SMART: aldehyde ferredoxin oxidoreductase; SPTR: aldehyde ferredoxin oxidoreductase; PFAM: aldehyde ferredoxin oxidoreductase, N-terminal domain; aldehyde ferredoxin oxidoreductase, domains 2 & 3; aldehyde ferredoxin oxidoreductase complement(1201914..1204013) Spirochaeta smaragdinae DSM 11293 9489227 YP_003802869.1 CDS Spirs_1145 NC_014364.1 1204055 1204759 R COGs: COG0437 Fe-S-cluster-containing hydrogenase components 1; InterProIPR017900:IPR001450:IPR017909:IPR017896:IPR 006311; KEGG: aoe:Clos_2144 hypothetical protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; TIGRFAM: Tat (twin-arginine translocation) pathway signal sequence; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(1204055..1204759) Spirochaeta smaragdinae DSM 11293 9489228 YP_003802870.1 CDS Spirs_1146 NC_014364.1 1204859 1205113 R KEGG: htu:Htur_0036 von Willebrand factor A; SPTR: von Willebrand factor A; hypothetical protein complement(1204859..1205113) Spirochaeta smaragdinae DSM 11293 9489229 YP_003802871.1 CDS Spirs_1147 NC_014364.1 1205267 1206052 D COGs: COG2014 conserved hypothetical protein; InterPro IPR007161; KEGG: sth:STH655 hypothetical protein; PFAM: protein of unknown function DUF364; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF364); hypothetical protein 1205267..1206052 Spirochaeta smaragdinae DSM 11293 9489230 YP_003802872.1 CDS Spirs_1148 NC_014364.1 1206033 1206809 R COGs: COG1975 xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777:IPR014308; KEGG: nth:Nther_2211 protein of unknown function DUF182; PFAM: protein of unknown function DUF182; SPTR: xanthine dehydrogenase accessory factor; TIGRFAM: xanthine dehydrogenase accessory protein XdhC; PFAM: XdhC and CoxI family; TrkA-N domain; TIGRFAM: xanthine dehydrogenase accessory protein XdhC; xanthine dehydrogenase accessory protein XdhC complement(1206033..1206809) Spirochaeta smaragdinae DSM 11293 9489231 YP_003802873.1 CDS Spirs_1149 NC_014364.1 1206965 1207378 D COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: tte:TTE2480 major membrane immunogen precursor; PFAM: FMN-binding domain protein; SPTR: Major membrane immunogen; PFAM: FMN-binding domain; FMN-binding domain-containing protein 1206965..1207378 Spirochaeta smaragdinae DSM 11293 9489232 YP_003802874.1 CDS Spirs_1150 NC_014364.1 1207583 1208644 D COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: aoe:Clos_0927 mandelate racemase/muconate lactonizing protein; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: mandelate racemase/muconate lactonizing protein; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; mandelate racemase / muconate lactonizing enzyme, N-terminal domain; mandelate racemase/muconate lactonizing protein 1207583..1208644 Spirochaeta smaragdinae DSM 11293 9489233 YP_003802875.1 CDS Spirs_1151 NC_014364.1 1208663 1209757 R COGs: COG1680 beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: dal:Dalk_3805 beta-lactamase; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase; beta-lactamase complement(1208663..1209757) Spirochaeta smaragdinae DSM 11293 9489234 YP_003802876.1 CDS Spirs_1152 NC_014364.1 1209744 1210649 R COGs: COG2103 sugar phosphate isomerase; InterPro IPR005486:IPR001347:IPR005488; KEGG: hap:HAPS_0707 N-acetylmuramic acid-6-phosphate etherase; PFAM: sugar isomerase (SIS); SPTR: N-acetylmuramic acid 6-phosphate etherase; TIGRFAM: glucokinase regulatory-like protein; PFAM: SIS domain; TIGRFAM: N-acetylmuramic acid 6-phosphate etherase; glucokinase regulatory-like protein complement(1209744..1210649) Spirochaeta smaragdinae DSM 11293 9489235 YP_003802877.1 CDS Spirs_1153 NC_014364.1 1210673 1211812 R COGs: COG2377 molecular chaperone distantly related to HSP70-fold metalloprotease; InterPro IPR005338; KEGG: tte:TTE0217 anhydro-N-acetylmuramic acid kinase; PFAM: protein of unknown function UPF0075; SPTR: uncharacterized protein anmK; PFAM: Uncharacterised protein family (UPF0075); hypothetical protein complement(1210673..1211812) Spirochaeta smaragdinae DSM 11293 9489236 YP_003802878.1 CDS Spirs_1154 NC_014364.1 1211956 1213503 D COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: tle:Tlet_1688 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: ABC-type dipeptide transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein 1211956..1213503 Spirochaeta smaragdinae DSM 11293 9489237 YP_003802879.1 CDS Spirs_1155 NC_014364.1 1213522 1214502 D COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: mrb:Mrub_0163 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1213522..1214502 Spirochaeta smaragdinae DSM 11293 9489238 YP_003802880.1 CDS Spirs_1156 NC_014364.1 1214527 1215357 D COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: sti:Sthe_1511 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1214527..1215357 Spirochaeta smaragdinae DSM 11293 9489239 YP_003802881.1 CDS Spirs_1157 NC_014364.1 1215367 1216353 D COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003439:IPR013563:IPR003593:IPR 010066; KEGG: hor:Hore_04930 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: ABC-type dipeptide/oligopeptide/nickel transporter; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 1215367..1216353 Spirochaeta smaragdinae DSM 11293 9489240 YP_003802882.1 CDS Spirs_1158 NC_014364.1 1216346 1217311 D COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterProIPR017871:IPR003439:IPR013563:IPR003593:IPR 010066; KEGG: gwc:GWCH70_0478 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 1216346..1217311 Spirochaeta smaragdinae DSM 11293 9489241 YP_003802883.1 CDS Spirs_1159 NC_014364.1 1217319 1217786 R InterPro IPR000182; KEGG: bcl:ABC0535 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1217319..1217786) Spirochaeta smaragdinae DSM 11293 9489242 YP_003802884.1 CDS Spirs_1160 NC_014364.1 1217816 1218325 D COGs: COG0456 acetyltransferase; InterPro IPR000182; KEGG: gau:GAU_3340 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 1217816..1218325 Spirochaeta smaragdinae DSM 11293 9489243 YP_003802885.1 CDS Spirs_1162 NC_014364.1 1219400 1220902 D COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR019800:IPR001764; KEGG: kol:Kole_1989 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase family 3 domain protein; SPTR: beta-N-acetylhexosaminidase; PFAM: glycosyl hydrolase family 3 N terminal domain; glycoside hydrolase 1219400..1220902 Spirochaeta smaragdinae DSM 11293 9489245 YP_003802886.1 CDS Spirs_1163 NC_014364.1 1220899 1221753 D COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: cac:CAC0191 RpiR family transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: Uncharacterized HTH-type transcriptional regulator CA_C0191; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator 1220899..1221753 Spirochaeta smaragdinae DSM 11293 9489246 YP_003802887.1 CDS Spirs_1164 NC_014364.1 1221858 1223588 D COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: pmo:Pmob_0482 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: extracellular solute-binding protein family 5; PFAM: Bacterial Ig-like domain (group 3); Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein 1221858..1223588 Spirochaeta smaragdinae DSM 11293 9489247 YP_003802888.1 CDS Spirs_1165 NC_014364.1 1223656 1224642 D COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: pmo:Pmob_0481 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1223656..1224642 Spirochaeta smaragdinae DSM 11293 9489248 YP_003802889.1 CDS Spirs_1166 NC_014364.1 1224639 1225496 D COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: pmo:Pmob_0480 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1224639..1225496 Spirochaeta smaragdinae DSM 11293 9489249 YP_003802890.1 CDS Spirs_1167 NC_014364.1 1225500 1226474 D COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003439:IPR013563:IPR003593:IPR 010066; KEGG: asa:ASA_3103 ABC-type oligopeptide transporter ATP-binding protein; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: ABC-type oligopeptide transporter ATP-binding protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 1225500..1226474 Spirochaeta smaragdinae DSM 11293 9489250 YP_003802891.1 CDS Spirs_1168 NC_014364.1 1226471 1227439 D COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003439:IPR013563:IPR003593:IPR 010066; KEGG: ttr:Tter_2072 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase 1226471..1227439 Spirochaeta smaragdinae DSM 11293 9489251 YP_003802892.1 CDS Spirs_1169 NC_014364.1 1227561 1228580 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tex:Teth514_0161 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 1227561..1228580 Spirochaeta smaragdinae DSM 11293 9489252 YP_003802893.1 CDS Spirs_1170 NC_014364.1 1228655 1229635 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: rxy:Rxyl_1889 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1228655..1229635 Spirochaeta smaragdinae DSM 11293 9489253 YP_003802894.1 CDS Spirs_1171 NC_014364.1 1229632 1231137 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: dth:DICTH_1535 ribose transport ATP-binding protein RbsA; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ribose transport ATP-binding protein RbsA; PFAM: ABC transporter; ABC transporter 1229632..1231137 Spirochaeta smaragdinae DSM 11293 9489254 YP_003802895.1 CDS Spirs_1172 NC_014364.1 1231219 1232193 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: rxy:Rxyl_1890 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1231219..1232193 Spirochaeta smaragdinae DSM 11293 9489255 YP_003802896.1 CDS Spirs_1173 NC_014364.1 1232262 1233179 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611:IPR002139; KEGG: rxy:Rxyl_1888 PfkB; PFAM: PfkB domain protein; SPTR: PfkB; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase; PfkB domain-containing protein 1232262..1233179 Spirochaeta smaragdinae DSM 11293 9489256 YP_003802897.1 CDS Spirs_1174 NC_014364.1 1233218 1233685 D COGs: COG1869 ABC-type ribose transporter auxiliary component; InterPro IPR007721; KEGG: rxy:Rxyl_1892 RbsD or FucU transport; PFAM: RbsD or FucU transport; SPTR: D-ribose pyranase 2; PFAM: RbsD / FucU transport protein family; RbsD or FucU transporter 1233218..1233685 Spirochaeta smaragdinae DSM 11293 9489257 YP_003802898.1 CDS Spirs_1175 NC_014364.1 1233697 1234386 D COGs: COG0274 deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: ypb:YPTS_3797 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: deoxyribose-phosphate aldolase; SPTR: deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase 1233697..1234386 Spirochaeta smaragdinae DSM 11293 9489258 YP_003802899.1 CDS Spirs_1176 NC_014364.1 1234399 1235556 D COGs: COG0407 uroporphyrinogen-III decarboxylase; KEGG: ote:Oter_2886 uroporphyrinogen-III decarboxylase-like protein; SPTR: uncharacterized protein; PFAM: uroporphyrinogen decarboxylase (URO-D); uroporphyrinogen-III decarboxylase-like protein 1234399..1235556 Spirochaeta smaragdinae DSM 11293 9489259 YP_003802900.1 CDS Spirs_1177 NC_014364.1 1235625 1236515 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611:IPR002139; KEGG: hch:HCH_02313 ribokinase family sugar kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase; PfkB domain-containing protein complement(1235625..1236515) Spirochaeta smaragdinae DSM 11293 9489260 YP_003802901.1 CDS Spirs_1178 NC_014364.1 1236540 1237898 R COGs: COG2848 conserved hypothetical protein; InterPro IPR007841; KEGG: hor:Hore_14430 hypothetical protein; PFAM: protein of unknown function DUF711; SPTR: UPF0210 protein Hore_14430; PFAM: Uncharacterized ACR (DUF711); hypothetical protein complement(1236540..1237898) Spirochaeta smaragdinae DSM 11293 9489261 YP_003802902.1 CDS Spirs_1179 NC_014364.1 1237902 1238186 R COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: hor:Hore_14440 ACT domain-containing protein; PFAM: amino acid-binding ACT domain protein; SPTR: ACT domain-containing protein; PFAM: ACT domain; ACT domain-containing protein complement(1237902..1238186) Spirochaeta smaragdinae DSM 11293 9489262 YP_003802903.1 CDS Spirs_1180 NC_014364.1 1238315 1239298 D COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: gau:GAU_0026 lipoprotein; PFAM: basic membrane lipoprotein; SPTR: uncharacterized protein; PFAM: Basic membrane protein; basic membrane lipoprotein 1238315..1239298 Spirochaeta smaragdinae DSM 11293 9489263 YP_003802904.1 CDS Spirs_1181 NC_014364.1 1239321 1239836 D COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: mta:Moth_1961 (2Fe-2S)-binding; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein 1239321..1239836 Spirochaeta smaragdinae DSM 11293 9489264 YP_003802905.1 CDS Spirs_1182 NC_014364.1 1239812 1240906 D COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: sme:SM_b20126 sugar ABC transporter permease; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1239812..1240906 Spirochaeta smaragdinae DSM 11293 9489265 YP_003802906.1 CDS Spirs_1183 NC_014364.1 1240903 1241820 D COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: drm:Dred_2766 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Sugar ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 1240903..1241820 Spirochaeta smaragdinae DSM 11293 9489266 YP_003802907.1 CDS Spirs_1184 NC_014364.1 1241837 1243372 D COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR017871:IPR003439:IPR003593; KEGG: hor:Hore_08780 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 1241837..1243372 Spirochaeta smaragdinae DSM 11293 9489267 YP_003802908.1 CDS Spirs_1185 NC_014364.1 1243451 1244116 D COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: cdl:CDR20291_1993 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 1243451..1244116 Spirochaeta smaragdinae DSM 11293 9489268 YP_003802909.1 CDS Spirs_1186 NC_014364.1 1244113 1245708 R COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594:IPR005467; KEGG: mbn:Mboo_1496 signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase complement(1244113..1245708) Spirochaeta smaragdinae DSM 11293 9489269 YP_003802910.1 CDS Spirs_1187 NC_014364.1 1245857 1249549 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR011110:IPR011123:IPR003661:IPR003594:IPR 001789:IPR005467:IPR004358; KEGG: sus:acid_4777 histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; Two component regulator three Y domain protein; Two component regulator propeller; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: Y_Y_Y domain; Two component regulator propeller; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; histidine kinase 1245857..1249549 Spirochaeta smaragdinae DSM 11293 9489270 YP_003802911.1 CDS Spirs_1188 NC_014364.1 1249879 1250454 D KEGG: bgl:bglu_1g14020 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1249879..1250454 Spirochaeta smaragdinae DSM 11293 9489271 YP_003802912.1 CDS Spirs_1189 NC_014364.1 1250470 1250970 D COGs: COG0645 kinase; KEGG: dsa:Desal_1319 kinase; SPTR: Kinase; PFAM: Chromatin associated protein KTI12; kinase 1250470..1250970 Spirochaeta smaragdinae DSM 11293 9489272 YP_003802913.1 CDS Spirs_1190 NC_014364.1 1251205 1252263 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: abu:Abu_1042 NADP-dependent alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; SPTR: NADP-dependent alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 1251205..1252263 Spirochaeta smaragdinae DSM 11293 9489273 YP_003802914.1 CDS Spirs_1191 NC_014364.1 1252567 1253763 D InterPro IPR018114:IPR013247; KEGG: lbf:LBF_0603 metalloendoprotease; PFAM: SH3 type 3 domain protein; SPTR: metalloendopeptidase, M23B family; signal peptide; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 1252567..1253763 Spirochaeta smaragdinae DSM 11293 9489274 YP_003802915.1 CDS Spirs_1192 NC_014364.1 1253778 1254956 D KEGG: tde:TDE1705 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1253778..1254956 Spirochaeta smaragdinae DSM 11293 9489275 YP_003802916.1 CDS Spirs_1193 NC_014364.1 1255002 1255574 D COGs: COG4843 conserved hypothetical protein; InterPro IPR019264; KEGG: mem:Memar_1511 hypothetical protein; PFAM: protein of unknown function DUF2179; SPTR: UPF0316 protein Memar_1511; PFAM: Uncharacterized protein conserved in bacteria (DUF2179); hypothetical protein 1255002..1255574 Spirochaeta smaragdinae DSM 11293 9489276 YP_003802917.1 CDS Spirs_1194 NC_014364.1 1255585 1256046 D COGs: COG0456 acetyltransferase; InterPro IPR000182; KEGG: pca:Pcar_0274 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 1255585..1256046 Spirochaeta smaragdinae DSM 11293 9489277 YP_003802918.1 CDS Spirs_1195 NC_014364.1 1256057 1257163 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261:IPR002933:IPR011650; KEGG: sfu:Sfum_0989 peptidase M20; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase M20; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; peptidase M20 1256057..1257163 Spirochaeta smaragdinae DSM 11293 9489278 YP_003802919.1 CDS Spirs_1196 NC_014364.1 1257160 1259637 R COGs: COG3250 beta-galactosidase/beta-glucuronidase; KEGG: avi:Avi_2405 beta-mannosidase precursor; PRIAM: beta-mannosidase; SPTR: beta-mannosidase; PFAM: domain; glycosyl hydrolases family 2, TIM barrel domain; beta-mannosidase complement(1257160..1259637) Spirochaeta smaragdinae DSM 11293 9489279 YP_003802920.1 CDS Spirs_1197 NC_014364.1 1259818 1260990 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: gym:GYMC10_5579 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein 1259818..1260990 Spirochaeta smaragdinae DSM 11293 9489280 YP_003802921.1 CDS Spirs_1198 NC_014364.1 1261155 1262444 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gtn:GTNG_3244 sugar ABC transporter sugar-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1261155..1262444 Spirochaeta smaragdinae DSM 11293 9489281 YP_003802922.1 CDS Spirs_1199 NC_014364.1 1262511 1263413 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: oih:OB0775 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1262511..1263413 Spirochaeta smaragdinae DSM 11293 9489282 YP_003802923.1 CDS Spirs_1200 NC_014364.1 1263427 1264545 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_2806 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1263427..1264545 Spirochaeta smaragdinae DSM 11293 9489283 YP_003802924.1 CDS Spirs_1201 NC_014364.1 1264551 1266299 D InterPro IPR001701; KEGG: aha:AHA_3098 endochitinase; PFAM: glycoside hydrolase family 9; SPTR: beta-glucosidase; PFAM: glycosyl hydrolase family 9; glycoside hydrolase family protein 1264551..1266299 Spirochaeta smaragdinae DSM 11293 9489284 YP_003802925.1 CDS Spirs_1202 NC_014364.1 1266296 1268089 D COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR015883:IPR001540; KEGG: fno:Fnod_0488 glycoside hydrolase family protein; PFAM: glycoside hydrolase, family 20, catalytic core; SPTR: glycoside hydrolase family 20; PFAM: glycosyl hydrolase family 20, catalytic domain; glycoside hydrolase family protein 1266296..1268089 Spirochaeta smaragdinae DSM 11293 9489285 YP_003802926.1 CDS Spirs_1203 NC_014364.1 1268217 1270793 R COGs: COG2898 conserved hypothetical protein; InterPro IPR007424:IPR007425:IPR007426; KEGG: mba:Mbar_A2435 hypothetical protein; PFAM: protein of unknown function DUF470; protein of unknown function DUF471; protein of unknown function DUF472; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2156); Uncharacterised protein family (UPF0104); hypothetical protein complement(1268217..1270793) Spirochaeta smaragdinae DSM 11293 9489286 YP_003802927.1 CDS Spirs_1204 NC_014364.1 1270861 1271658 R COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: rci:LRC327 ABC-type cobalt import system, permease; PFAM: cobalt transporter; SPTR: ABC-type cobalt import system, permease component; PFAM: Cobalt transporter; cobalt transporter complement(1270861..1271658) Spirochaeta smaragdinae DSM 11293 9489287 YP_003802928.1 CDS Spirs_1205 NC_014364.1 1271666 1273390 R COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR017871:IPR003439:IPR003593; KEGG: mba:Mbar_A3550 cobalt transport ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Cobalt transport ATP-binding protein; PFAM: ABC transporter; TIGRFAM: cobalt transporter ATP-binding subunit; ABC transporter complement(1271666..1273390) Spirochaeta smaragdinae DSM 11293 9489288 YP_003802929.1 CDS Spirs_1206 NC_014364.1 1273422 1274195 R COGs: COG1402 Uncharacterized protein amidase; InterPro IPR003785; KEGG: uncharacterized protein, amidase; PFAM: creatininase; SPTR: creatininase; PFAM: Creatinine amidohydrolase; creatininase complement(1273422..1274195) Spirochaeta smaragdinae DSM 11293 9489289 YP_003802930.1 CDS Spirs_1207 NC_014364.1 1274242 1274802 R COGs: COG4721 membrane protein; InterPro IPR017195; KEGG: mgi:Mflv_0970 ABC transporter permease; PFAM: ABC-type thiamin-related transporter, permease 1, predicted; SPTR: ABC transporter permease; PFAM: ABC-type cobalt transporter, permease; thiamin-like ABC transporter permease complement(1274242..1274802) Spirochaeta smaragdinae DSM 11293 9489290 YP_003802931.1 CDS Spirs_1208 NC_014364.1 1274827 1275264 R COGs: COG1522 transcriptional regulators; InterPro IPR019887:IPR000485:IPR019888; KEGG: pho:PH1692 transcriptional regulator; PFAM: transcription regulator, AsnC-type-like; SMART: transcription regulator, AsnC-type; SPTR: uncharacterized protein; PFAM: AsnC family; AsnC family transcriptional regulator complement(1274827..1275264) Spirochaeta smaragdinae DSM 11293 9489291 YP_003802932.1 CDS Spirs_1209 NC_014364.1 1275495 1275950 D COGs: COG2606 conserved hypothetical protein; InterPro IPR007214; KEGG: emi:Emin_0821 YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: YbaK/prolyl-tRNA synthetase associated region; PFAM: YbaK / prolyl-tRNA synthetases associated domain; YbaK/prolyl-tRNA synthetase associated protein 1275495..1275950 Spirochaeta smaragdinae DSM 11293 9489292 YP_003802933.1 CDS Spirs_1210 NC_014364.1 1276188 1277270 R InterPro IPR011493; KEGG: swo:Swol_1078 Ig-like domain-containing protein; PFAM: GLUG domain protein; SPTR: Surface proteins containing Ig-like domains-like; PFAM: The GLUG motif; GLUG domain-containing protein complement(1276188..1277270) Spirochaeta smaragdinae DSM 11293 9489293 YP_003802934.1 CDS Spirs_1213 NC_014364.1 1278910 1280208 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ttr:Tter_2659 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1278910..1280208 Spirochaeta smaragdinae DSM 11293 9489296 YP_003802935.1 CDS Spirs_1214 NC_014364.1 1280273 1281175 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: ttr:Tter_2658 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1280273..1281175 Spirochaeta smaragdinae DSM 11293 9489297 YP_003802936.1 CDS Spirs_1215 NC_014364.1 1281176 1282057 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ttr:Tter_2657 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1281176..1282057 Spirochaeta smaragdinae DSM 11293 9489298 YP_003802937.1 CDS Spirs_1216 NC_014364.1 1282075 1284429 D COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR019800:IPR001764:IPR002772; KEGG: esa:ESA_02100 hypothetical protein; PFAM: glycoside hydrolase; SPTR: uncharacterized protein; PFAM: glycosyl hydrolase family 3 C terminal domain; glycosyl hydrolase family 3 N terminal domain; glycoside hydrolase 1282075..1284429 Spirochaeta smaragdinae DSM 11293 9489299 YP_003802938.1 CDS Spirs_1217 NC_014364.1 1284482 1286818 D COGs: COG1609 transcriptional regulators; InterPro IPR001761:IPR003594; KEGG: dtu:Dtur_1753 diguanylate cyclase and metal dependent phosphohydrolase; PFAM: ATP-binding region ATPase domain protein; periplasmic binding protein/LacI transcriptional regulator; SMART: ATP-binding region ATPase domain protein; SPTR: Diguanylate cyclase and metal dependent phosphohydrolase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; family; ATP-binding region ATPase domain-containing protein 1284482..1286818 Spirochaeta smaragdinae DSM 11293 9489300 YP_003802939.1 CDS Spirs_1218 NC_014364.1 1286828 1287481 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: rmr:Rmar_2227 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 1286828..1287481 Spirochaeta smaragdinae DSM 11293 9489301 YP_003802940.1 CDS Spirs_1219 NC_014364.1 1287457 1288116 D COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: dth:DICTH_0345 xylanase; PFAM: polysaccharide deacetylase; SPTR: Xylanase; PFAM: polysaccharide deacetylase; polysaccharide deacetylase 1287457..1288116 Spirochaeta smaragdinae DSM 11293 9489302 YP_003802941.1 CDS Spirs_1220 NC_014364.1 1288168 1289550 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: ret:RHE_PC00089 hydrolase protein; PFAM: amidohydrolase; SPTR: uncharacterized protein; PFAM: Amidohydrolase family; amidohydrolase complement(1288168..1289550) Spirochaeta smaragdinae DSM 11293 9489303 YP_003802942.1 CDS Spirs_1221 NC_014364.1 1289775 1290662 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: gym:GYMC10_0714 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1289775..1290662 Spirochaeta smaragdinae DSM 11293 9489304 YP_003802943.1 CDS Spirs_1222 NC_014364.1 1290659 1291498 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_0715 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1290659..1291498 Spirochaeta smaragdinae DSM 11293 9489305 YP_003802944.1 CDS Spirs_1223 NC_014364.1 1291530 1292795 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006061:IPR006059; KEGG: gym:GYMC10_5603 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1291530..1292795 Spirochaeta smaragdinae DSM 11293 9489306 YP_003802945.1 CDS Spirs_1224 NC_014364.1 1292819 1295188 D COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR019800:IPR001764:IPR002772; KEGG: cth:Cthe_1256 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 3 domain protein; SPTR: Thermostable beta-glucosidase B; PFAM: glycosyl hydrolase family 3 C terminal domain; glycosyl hydrolase family 3 N terminal domain; glycoside hydrolase 1292819..1295188 Spirochaeta smaragdinae DSM 11293 9489307 YP_003802946.1 CDS Spirs_1225 NC_014364.1 1295185 1296066 R COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR003313:IPR000005:IPR018060:IPR020449; KEGG: bwe:BcerKBAB4_2057 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; AraC protein arabinose-binding/dimerisation; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(1295185..1296066) Spirochaeta smaragdinae DSM 11293 9489308 YP_003802947.1 CDS Spirs_1226 NC_014364.1 1296353 1297738 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_3548 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1296353..1297738 Spirochaeta smaragdinae DSM 11293 9489309 YP_003802948.1 CDS Spirs_1227 NC_014364.1 1297828 1298715 D COGs: COG4209 ABC-type polysaccharide transporter permease; InterPro IPR000515; KEGG: gym:GYMC10_3547 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1297828..1298715 Spirochaeta smaragdinae DSM 11293 9489310 YP_003802949.1 CDS Spirs_1228 NC_014364.1 1298708 1299571 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_3546 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1298708..1299571 Spirochaeta smaragdinae DSM 11293 9489311 YP_003802950.1 CDS Spirs_1229 NC_014364.1 1299575 1300645 D COGs: COG1609 transcriptional regulators; InterPro IPR000524; KEGG: hor:Hore_15050 regulatory protein GntR HTH; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Regulatory protein GntR HTH; PFAM: Bacterial regulatory proteins, gntR family; family; regulatory protein GntR 1299575..1300645 Spirochaeta smaragdinae DSM 11293 9489312 YP_003802951.1 CDS Spirs_1230 NC_014364.1 1300602 1302095 D InterPro IPR004013; KEGG: nca:Noca_3849 phosphotransferase domain-containing protein; PFAM: PHP domain protein; SPTR: PHP C-terminal domain protein; PHP domain-containing protein 1300602..1302095 Spirochaeta smaragdinae DSM 11293 9489313 YP_003802952.1 CDS Spirs_1231 NC_014364.1 1302097 1304184 D KEGG: gym:GYMC10_2685 glycoside hydrolase family 38; SPTR: glycoside hydrolase family 38; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; glycoside hydrolase family protein 1302097..1304184 Spirochaeta smaragdinae DSM 11293 9489314 YP_003802953.1 CDS Spirs_1232 NC_014364.1 1304181 1307261 D COGs: COG0383 alpha-mannosidase; InterPro IPR000602:IPR015341:IPR011682; KEGG: tps:THAPS_263310 cytosolic alpha-mannosidase; PFAM: glycoside hydrolase family 38; glycoside hydrolase family 38 central region; glycosyl hydrolase 38 domain protein; PRIAM: alpha-mannosidase; SPTR: alpha-mannosidase; PFAM: glycosyl hydrolases family 38 N-terminal domain; alpha mannosidase, middle domain; alpha-mannosidase 1304181..1307261 Spirochaeta smaragdinae DSM 11293 9489315 YP_003802954.1 CDS Spirs_1233 NC_014364.1 1307530 1309866 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953; KEGG: dhd:Dhaf_1658 FMN-binding domain protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: uncharacterized protein; PFAM: FAD binding domain; FMN-binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein 1307530..1309866 Spirochaeta smaragdinae DSM 11293 9489316 YP_003802955.1 CDS Spirs_1234 NC_014364.1 1310141 1310728 D InterPro IPR001647; KEGG: rci:RCIX2177 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcription regulator (TetR family); PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 1310141..1310728 Spirochaeta smaragdinae DSM 11293 9489317 YP_003802956.1 CDS Spirs_1235 NC_014364.1 1310832 1312106 R COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: tau:Tola_2010 glycoside hydrolase family 4; PFAM: glycoside hydrolase family 4; SPTR: alpha-galactosidase, ; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; glycoside hydrolase family protein complement(1310832..1312106) Spirochaeta smaragdinae DSM 11293 9489318 YP_003802957.1 CDS Spirs_1236 NC_014364.1 1312103 1313497 R COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088; KEGG: bld:BLi01143 MelA; PFAM: glycoside hydrolase family 4; SPTR: alpha-D-galactoside galactohydrolase, glycoside Hydrolase Family 4,MelA; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; glycoside hydrolase family protein complement(1312103..1313497) Spirochaeta smaragdinae DSM 11293 9489319 YP_003802958.1 CDS Spirs_1237 NC_014364.1 1313513 1314487 R COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: cpy:Cphy_2660 aldose 1-epimerase; PFAM: aldose 1-epimerase; SPTR: aldose 1-epimerase family protein; PFAM: aldose 1-epimerase; aldose 1-epimerase complement(1313513..1314487) Spirochaeta smaragdinae DSM 11293 9489320 YP_003802959.1 CDS Spirs_1238 NC_014364.1 1314498 1315523 R COGs: COG4211 ABC-type glucose/galactose transporter permease; InterPro IPR001991:IPR001851; KEGG: bhy:BHWA1_02550 beta-methylgalactoside transporter inner membrane component; PFAM: inner-membrane translocator; SPTR: Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(1314498..1315523) Spirochaeta smaragdinae DSM 11293 9489321 YP_003802960.1 CDS Spirs_1239 NC_014364.1 1315539 1317041 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593:IPR015862; KEGG: apj:APJL_1451 galactose/methyl galaxtoside transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Galactoside transport ATP-binding protein MglA; PFAM: ABC transporter; ABC transporter complement(1315539..1317041) Spirochaeta smaragdinae DSM 11293 9489322 YP_003802961.1 CDS Spirs_1240 NC_014364.1 1317105 1318142 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: cpe:CPE1341 galactoside ABC transporter; SPTR: Probable galactoside ABC transporter; PFAM: family; galactoside ABC transporter complement(1317105..1318142) Spirochaeta smaragdinae DSM 11293 9489323 YP_003802962.1 CDS Spirs_1241 NC_014364.1 1318338 1319573 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600:IPR000835; KEGG: bha:BH1094 transcriptional repressor of the xylose operon; PFAM: ROK family protein; regulatory protein MarR; SPTR: ROK family protein; PFAM: ROK family; MarR family; ROK family protein complement(1318338..1319573) Spirochaeta smaragdinae DSM 11293 9489324 YP_003802963.1 CDS Spirs_1242 NC_014364.1 1319675 1320004 R InterPro IPR008407; KEGG: wsu:WS1319 hypothetical protein; PFAM: branched-chain amino acid transport; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter (AzlD); branched-chain amino acid transport complement(1319675..1320004) Spirochaeta smaragdinae DSM 11293 9489325 YP_003802964.1 CDS Spirs_1243 NC_014364.1 1320001 1320690 R COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: ckr:CKR_2515 hypothetical protein; PFAM: AzlC family protein; SPTR: uncharacterized protein; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC; AzlC family protein complement(1320001..1320690) Spirochaeta smaragdinae DSM 11293 9489326 YP_003802965.1 CDS Spirs_1244 NC_014364.1 1320840 1323500 D COGs: COG2909 ATP-dependent transcriptional regulator protein; InterPro IPR000792:IPR001440:IPR019734:IPR013026; KEGG: bbe:BBR47_14470 probable transcriptional regulator; PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; Tetratricopeptide repeat; SPTR: Probable transcriptional regulator; PFAM: Bacterial regulatory proteins, luxR family; ATP-dependent transcriptional regulator, MalT-like, LuxR family 1320840..1323500 Spirochaeta smaragdinae DSM 11293 9489327 YP_003802966.1 CDS Spirs_1245 NC_014364.1 1323595 1325115 D COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: aco:Amico_0594 radical SAM protein; PFAM: radical SAM domain protein; SPTR: radical SAM protein; PFAM: radical SAM superfamily; radical SAM protein 1323595..1325115 Spirochaeta smaragdinae DSM 11293 9489328 YP_003802967.1 CDS Spirs_1246 NC_014364.1 1325099 1326826 R COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003660:IPR011495; KEGG: cyn:Cyan7425_1001 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase; PFAM: histidine kinase; HAMP domain; signal transduction histidine kinase complement(1325099..1326826) Spirochaeta smaragdinae DSM 11293 9489329 YP_003802968.1 CDS Spirs_1247 NC_014364.1 1326875 1328164 R COGs: COG0577 ABC-type antimicrobial peptide transport system permease; InterPro IPR003838; KEGG: apv:Apar_0230 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: Abc transporter permease; PFAM: Predicted permease; hypothetical protein complement(1326875..1328164) Spirochaeta smaragdinae DSM 11293 9489330 YP_003802969.1 CDS Spirs_1248 NC_014364.1 1328174 1329454 R InterPro IPR003838; KEGG: pst:PSPTO_2832 syringolide efflux protein SyfD; PFAM: protein of unknown function DUF214; SPTR: Macrolide export ATP-binding/permease macB 2; PFAM: Predicted permease; hypothetical protein complement(1328174..1329454) Spirochaeta smaragdinae DSM 11293 9489331 YP_003802970.1 CDS Spirs_1249 NC_014364.1 1329454 1330140 R COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: tna:CTN_0280 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(1329454..1330140) Spirochaeta smaragdinae DSM 11293 9489332 YP_003802971.1 CDS Spirs_1250 NC_014364.1 1330323 1332014 D COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: aba:acid345_3062 periplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 1330323..1332014 Spirochaeta smaragdinae DSM 11293 9489333 YP_003802972.1 CDS Spirs_1251 NC_014364.1 1331992 1332687 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: sus:acid_1101 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 1331992..1332687 Spirochaeta smaragdinae DSM 11293 9489334 YP_003802973.1 CDS Spirs_1252 NC_014364.1 1332697 1333293 R InterPro IPR013216; KEGG: cai:Caci_2025 methyltransferase type 12; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: Tellurite resistance protein TehB; type 11 methyltransferase complement(1332697..1333293) Spirochaeta smaragdinae DSM 11293 9489335 YP_003802974.1 CDS Spirs_1253 NC_014364.1 1333305 1333760 R COGs: COG4807 conserved hypothetical protein; InterPro IPR009921; KEGG: yen:YE2874 hypothetical protein; PFAM: protein of unknown function DUF1456; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1456); hypothetical protein complement(1333305..1333760) Spirochaeta smaragdinae DSM 11293 9489336 YP_003802975.1 CDS Spirs_1254 NC_014364.1 1333823 1334452 R COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: mmw:Mmwyl1_2551 aldolase; PFAM: class II aldolase/adducin family protein; SPTR: uncharacterized protein; PFAM: class II Aldolase and Adducin N-terminal domain; class II aldolase/adducin family protein complement(1333823..1334452) Spirochaeta smaragdinae DSM 11293 9489337 YP_003802976.1 CDS Spirs_1255 NC_014364.1 1334449 1335696 R COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: bmr:BMI_II146 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF1537; type III effector Hrp-dependent outer protein complement(1334449..1335696) Spirochaeta smaragdinae DSM 11293 9489338 YP_003802977.1 CDS Spirs_1256 NC_014364.1 1335693 1337192 R COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: dhd:Dhaf_2075 protein of unknown function DUF112 transmembrane; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein complement(1335693..1337192) Spirochaeta smaragdinae DSM 11293 9489339 YP_003802978.1 CDS Spirs_1257 NC_014364.1 1337204 1337635 R KEGG: xau:Xaut_0483 hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctB family; hypothetical protein complement(1337204..1337635) Spirochaeta smaragdinae DSM 11293 9489340 YP_003802979.1 CDS Spirs_1258 NC_014364.1 1337741 1338724 R COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: sti:Sthe_3000 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein complement(1337741..1338724) Spirochaeta smaragdinae DSM 11293 9489341 YP_003802980.1 CDS Spirs_1259 NC_014364.1 1338993 1340381 R COGs: COG4091 homoserine dehydrogenase; KEGG: pde:Pden_3388 SAF domain-containing protein; SPTR: SAF domain protein; SAF domain-containing protein complement(1338993..1340381) Spirochaeta smaragdinae DSM 11293 9489342 YP_003802981.1 CDS Spirs_1260 NC_014364.1 1340585 1342492 D COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR010524:IPR002197:IPR003593; KEGG: tpd:Teth39_1679 sigma-54 dependent trancsriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; Propionate catabolism activator domain protein; helix-turn-helix Fis-type; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Propionate catabolism activator; Fis family transcriptional regulator 1340585..1342492 Spirochaeta smaragdinae DSM 11293 9489343 YP_003802982.1 CDS Spirs_1261 NC_014364.1 1342483 1342932 R COGs: COG1051 ADP-ribose pyrophosphatase; InterPro IPR020084:IPR020476:IPR000086; KEGG: hor:Hore_13970 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: ADP-ribose pyrophosphatase; PFAM: NUDIX domain; NUDIX hydrolase complement(1342483..1342932) Spirochaeta smaragdinae DSM 11293 9489344 YP_003802983.1 CDS Spirs_1262 NC_014364.1 1342929 1344140 R KEGG: pop:POPTR_548146 hypothetical protein; SPTR: RNA dependent RNA polymerase; hypothetical protein complement(1342929..1344140) Spirochaeta smaragdinae DSM 11293 9489345 YP_003802984.1 CDS Spirs_1263 NC_014364.1 1344207 1345001 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: ele:Elen_3022 ATP-dependent transcriptional regulator, MalT-like, LuxR family; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: DNA-binding response regulator, LuxR family; PFAM: Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(1344207..1345001) Spirochaeta smaragdinae DSM 11293 9489346 YP_003802985.1 CDS Spirs_1264 NC_014364.1 1345014 1346843 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterProIPR004358:IPR003439:IPR003661:IPR003594:IPR 003593:IPR005467; KEGG: aca:ACP_0181 sensor histidine kinase; PFAM: ABC transporter related; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; ATPase AAA; SPTR: Sensor protein; PFAM: ABC transporter; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; histidine kinase complement(1345014..1346843) Spirochaeta smaragdinae DSM 11293 9489347 YP_003802986.1 CDS Spirs_1265 NC_014364.1 1346827 1348182 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR002078:IPR020441:IPR001789:IPR002197:IPR 003593; KEGG: sat:SYN_01093 response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; ATPase AAA; SPTR: Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Fis family transcriptional regulator complement(1346827..1348182) Spirochaeta smaragdinae DSM 11293 9489348 YP_003802987.1 CDS Spirs_1266 NC_014364.1 1348367 1349626 D COGs: COG1957 inosine-uridine nucleoside N-ribohydrolase; InterPro IPR001910; KEGG: oan:Oant_2761 inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine/uridine-preferring nucleoside hydrolase; SPTR: inosine/uridine-preferring nucleoside hydrolase; PFAM: inosine-uridine preferring nucleoside hydrolase; inosine/uridine-preferring nucleoside hydrolase 1348367..1349626 Spirochaeta smaragdinae DSM 11293 9489349 YP_003802988.1 CDS Spirs_1267 NC_014364.1 1349941 1350912 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: rhi:NGR_c17380 ribose transport system, substrate-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ribose transporter, substrate-binding protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1349941..1350912 Spirochaeta smaragdinae DSM 11293 9489350 YP_003802989.1 CDS Spirs_1268 NC_014364.1 1350974 1352509 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: oan:Oant_2808 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Galactose/methyl galactoside import ATP-binding protein mglA; PFAM: ABC transporter; ABC transporter 1350974..1352509 Spirochaeta smaragdinae DSM 11293 9489351 YP_003802990.1 CDS Spirs_1269 NC_014364.1 1352502 1353488 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: rhi:NGR_c17360 ribose ABC transporter permease; PFAM: inner-membrane translocator; SPTR: ribose ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1352502..1353488 Spirochaeta smaragdinae DSM 11293 9489352 YP_003802991.1 CDS Spirs_1270 NC_014364.1 1353529 1354479 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: bpd:BURPS668_1853 ribose ABC transporter periplasmic ribose-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ribose transport system, substrate-binding protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1353529..1354479 Spirochaeta smaragdinae DSM 11293 9489353 YP_003802992.1 CDS Spirs_1271 NC_014364.1 1354472 1355440 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: rso:RSc1015 transmembrane ABC transporter protein; PFAM: inner-membrane translocator; SPTR: Probable ribose abc transporter permease abc transporter protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 1354472..1355440 Spirochaeta smaragdinae DSM 11293 9489354 YP_003802993.1 CDS Spirs_1272 NC_014364.1 1355449 1356246 R KEGG: cts:Ctha_1454 exporters of the RND superfamily-like protein; SPTR: Exporters of the RND superfamily-like protein; PFAM: protein of unknown function (DUF1329); exporters of the RND superfamily-like protein complement(1355449..1356246) Spirochaeta smaragdinae DSM 11293 9489355 YP_003802994.1 CDS Spirs_1273 NC_014364.1 1356234 1358534 R COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR018247:IPR000731; KEGG: cts:Ctha_1453 exporter of the RND superfamily protein-like protein; SPTR: antibiotic transport protein; PFAM: MMPL family; TIGRFAM: The (Largely Archaeal ) Hydrophobe/Amphiphile Efflux-3 (HAE3) Family; exporter of the RND superfamily protein complement(1356234..1358534) Spirochaeta smaragdinae DSM 11293 9489356 YP_003802995.1 CDS Spirs_1274 NC_014364.1 1358568 1359893 R KEGG: abb:ABBFA_003401 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1358568..1359893) Spirochaeta smaragdinae DSM 11293 9489357 YP_003802996.1 CDS Spirs_1275 NC_014364.1 1359954 1360529 R InterPro IPR001647; KEGG: fnu:FN0473 regulatory protein BetI; PFAM: regulatory protein TetR; SPTR: Regulatory protein betI; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(1359954..1360529) Spirochaeta smaragdinae DSM 11293 9489358 YP_003802997.1 CDS Spirs_1276 NC_014364.1 1360646 1361632 R COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: mlo:mll1744 hypothetical protein; PFAM: ADP-ribosylation/crystallin J1; SPTR: ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylglycohydrolase; ADP-ribosylation/crystallin J1 complement(1360646..1361632) Spirochaeta smaragdinae DSM 11293 9489359 YP_003802998.1 CDS Spirs_1277 NC_014364.1 1361629 1362585 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR002139:IPR011611; KEGG: ser:SERP2216 ribokinase, PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(1361629..1362585) Spirochaeta smaragdinae DSM 11293 9489360 YP_003802999.1 CDS Spirs_1278 NC_014364.1 1362588 1363664 R COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterProIPR017871:IPR003439:IPR013611:IPR005893:IPR 003593; KEGG: tro:trd_0881 ABC transporter ATP-binding protein; PFAM: ABC transporter related; transport-associated OB domain protein; SMART: AAA ATPase; SPTR: ABC transporter; TIGRFAM: spermidine/putrescine ABC transporter ATPase; PFAM: ABC transporter; TOBE domain; TIGRFAM: spermidine/putrescine ABC transporter ATP-binding subunit; spermidine/putrescine ABC transporter ATPase complement(1362588..1363664) Spirochaeta smaragdinae DSM 11293 9489361 YP_003803000.1 CDS Spirs_1279 NC_014364.1 1363664 1364467 R COGs: COG1177 ABC-type spermidine/putrescine transport system permease II; InterPro IPR000515; KEGG: mlo:mll1739 permease protein of polyamine ABC transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1363664..1364467) Spirochaeta smaragdinae DSM 11293 9489362 YP_003803001.1 CDS Spirs_1280 NC_014364.1 1364460 1365296 R COGs: COG1176 ABC-type spermidine/putrescine transport system permease I; InterPro IPR000515; KEGG: mlo:mll1740 permease protein of polyamine ABC transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1364460..1365296) Spirochaeta smaragdinae DSM 11293 9489363 YP_003803002.1 CDS Spirs_1281 NC_014364.1 1365391 1366452 R COGs: COG0687 Spermidine/putrescine-binding periplasmic protein; InterPro IPR001188:IPR006059; KEGG: mlo:mll1741 periplasmic spermidine/putrescine-binding protein or ABC transporter; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(1365391..1366452) Spirochaeta smaragdinae DSM 11293 9489364 YP_003803003.1 CDS Spirs_1282 NC_014364.1 1366511 1367077 R COGs: COG2188 transcriptional regulators; InterPro IPR000524; KEGG: kol:Kole_0877 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator complement(1366511..1367077) Spirochaeta smaragdinae DSM 11293 9489365 YP_003803004.1 CDS Spirs_1283 NC_014364.1 1367186 1368097 R COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: drm:Dred_2766 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(1367186..1368097) Spirochaeta smaragdinae DSM 11293 9489366 YP_003803005.1 CDS Spirs_1284 NC_014364.1 1368094 1369158 R COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: drm:Dred_2767 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Predicted protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(1368094..1369158) Spirochaeta smaragdinae DSM 11293 9489367 YP_003803006.1 CDS Spirs_1285 NC_014364.1 1369148 1370665 R COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR017871:IPR003439:IPR003593; KEGG: hor:Hore_08780 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC-type sugar transporter; PFAM: ABC transporter; ABC transporter complement(1369148..1370665) Spirochaeta smaragdinae DSM 11293 9489368 YP_003803007.1 CDS Spirs_1286 NC_014364.1 1370733 1371746 R COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: gau:GAU_0026 lipoprotein; PFAM: basic membrane lipoprotein; SPTR: Predicted protein; PFAM: Basic membrane protein; basic membrane lipoprotein complement(1370733..1371746) Spirochaeta smaragdinae DSM 11293 9489369 YP_003803008.1 CDS Spirs_1287 NC_014364.1 1372072 1372644 D COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; KEGG: oih:OB1065 hypothetical protein; SPTR: G:T/U mismatch-specific DNA glycosylase-like protein; PFAM: uracil DNA glycosylase superfamily; hypothetical protein 1372072..1372644 Spirochaeta smaragdinae DSM 11293 9489371 YP_003803009.1 CDS Spirs_1288 NC_014364.1 1372672 1374477 R COGs: COG1164 oligoendopeptidase F; InterPro IPR013647:IPR001567:IPR004438; KEGG: tde:TDE2639 oligoendopeptidase F; PFAM: peptidase M3A and M3B thimet/oligopeptidase F; oligopeptidase F; SPTR: oligoendopeptidase F; TIGRFAM: oligoendopeptidase F; PFAM: oligopeptidase F; peptidase family M3; TIGRFAM: oligoendopeptidase F; oligoendopeptidase F complement(1372672..1374477) Spirochaeta smaragdinae DSM 11293 9489372 YP_003803010.1 CDS Spirs_1289 NC_014364.1 1374488 1375087 R COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637; KEGG: tde:TDE2271 HAM1 protein; PFAM: Ham1 family protein; PRIAM: nucleoside-triphosphatase; SPTR: nucleoside-triphosphatase; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; RdgB/HAM1 family non-canonical purine NTP pyrophosphatase complement(1374488..1375087) Spirochaeta smaragdinae DSM 11293 9489373 YP_003803011.1 CDS Spirs_1290 NC_014364.1 1375139 1376041 R KEGG: tcr:511423.50 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1375139..1376041) Spirochaeta smaragdinae DSM 11293 9489374 YP_003803012.1 CDS Spirs_1291 NC_014364.1 1376136 1377116 R COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: tpp:TPASS_0436 hypothetical protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: DHH family protein, subfamily 1; PFAM: DHHA1 domain; DHH family; phosphoesterase RecJ domain-containing protein complement(1376136..1377116) Spirochaeta smaragdinae DSM 11293 9489375 YP_003803013.1 CDS Spirs_1292 NC_014364.1 1377196 1377615 R KEGG: tpp:TPASS_0437 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1377196..1377615) Spirochaeta smaragdinae DSM 11293 9489376 YP_003803014.1 CDS Spirs_1293 NC_014364.1 1377705 1380113 R COGs: COG0466 ATP-dependent Lon protease; InterProIPR008268:IPR001984:IPR003111:IPR003959:IPR 008269:IPR004815:IPR003593; KEGG: mta:Moth_0531 Lon-A peptidase; PFAM: peptidase S16; ATPase AAA; PRIAM: endopeptidase La; SMART: peptidase S16; ATPase AAA; SPTR: ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La; ATP-dependent protease La complement(1377705..1380113) Spirochaeta smaragdinae DSM 11293 9489377 YP_003803015.1 CDS Spirs_1294 NC_014364.1 1380110 1381351 R COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR010603:IPR013093:IPR019489:IPR004487:IPR 003593; KEGG: tde:TDE1673 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase AAA-2 domain protein; zinc finger C4 domain protein; Clp ATPase-like; SMART: ATPase AAA; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpX; TIGRFAM: ATP-dependent Clp protease ATP-binding subunit ClpX; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX); ATP-dependent Clp protease ATP-binding subunit ClpX complement(1380110..1381351) Spirochaeta smaragdinae DSM 11293 9489378 YP_003803016.1 CDS Spirs_1295 NC_014364.1 1381332 1381949 R COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR018215:IPR001907; KEGG: tde:TDE1672 ATP-dependent Clp protease proteolytic subunit; PFAM: peptidase S14 ClpP; PRIAM: endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP; ATP-dependent Clp protease proteolytic subunit ClpP complement(1381332..1381949) Spirochaeta smaragdinae DSM 11293 9489379 YP_003803017.1 CDS Spirs_1296 NC_014364.1 1381984 1383348 R COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR008881:IPR001179:IPR008880:IPR005215; KEGG: tde:TDE1671 trigger factor; PFAM: trigger factor domain protein; trigger factor domain; peptidylprolyl isomerase FKBP-type; SPTR: Trigger factor; TIGRFAM: trigger factor; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF) C-terminus; Bacterial trigger factor protein (TF); TIGRFAM: trigger factor; trigger factor complement(1381984..1383348) Spirochaeta smaragdinae DSM 11293 9489380 YP_003803018.1 CDS Spirs_1297 NC_014364.1 1384082 1386289 R COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: ava:Ava_B0112 recombination factor protein RarA/unknown domain fusion protein; PFAM: ATPase AAA; SMART: ATPase AAA; SPTR: recombination factor protein RarA; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA); ATPase AAA complement(1384082..1386289) Spirochaeta smaragdinae DSM 11293 9489386 YP_003803019.1 CDS Spirs_1298 NC_014364.1 1386386 1387267 D COGs: COG1366 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003594:IPR003658; KEGG: tde:TDE1121 hypothetical protein; PFAM: sulfate transporter/antisigma-factor antagonist STAS; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 1386386..1387267 Spirochaeta smaragdinae DSM 11293 9489387 YP_003803020.1 CDS Spirs_1299 NC_014364.1 1387272 1388501 R COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822:IPR001932:IPR000644; KEGG: mhu:Mhun_0060 serine phosphatase; PFAM: stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: serine phosphatase; PFAM: stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase complement(1387272..1388501) Spirochaeta smaragdinae DSM 11293 9489388 YP_003803021.1 CDS Spirs_1300 NC_014364.1 1388655 1388906 D KEGG: dma:DMR_03540 hypothetical protein; SPTR: uncharacterized protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; hypothetical protein 1388655..1388906 Spirochaeta smaragdinae DSM 11293 9489389 YP_003803022.1 CDS Spirs_1301 NC_014364.1 1388903 1390630 D COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR017900:IPR017871:IPR001450:IPR004108:IPR 007202:IPR017896; KEGG: sfu:Sfum_1846 PAS/PAC sensor protein; PFAM: hydrogenase large subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; SPTR: PAS/PAC sensor protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; hydrogenase large subunit domain-containing protein 1388903..1390630 Spirochaeta smaragdinae DSM 11293 9489390 YP_003803023.1 CDS Spirs_1302 NC_014364.1 1390617 1391807 D InterPro IPR010822:IPR001932; KEGG: sfu:Sfum_1847 stage II sporulation E family protein; PFAM: stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; SPTR: stage II sporulation E family protein; PFAM: stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 1390617..1391807 Spirochaeta smaragdinae DSM 11293 9489391 YP_003803024.1 CDS Spirs_1303 NC_014364.1 1391989 1392705 R COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123:IPR004552; KEGG: cbt:CLH_3257 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferase; manually curated; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1391989..1392705) Spirochaeta smaragdinae DSM 11293 9489392 YP_003803025.1 CDS Spirs_1304 NC_014364.1 1392801 1393505 D COGs: COG0670 integral membrane protein interacts with FtsH; InterPro IPR006214; KEGG: dat:HRM2_25640 cold-shock inducible membrane protein; PFAM: protein of unknown function UPF0005; SPTR: cold-shock inducible membrane protein; PFAM: Uncharacterised protein family UPF0005; hypothetical protein 1392801..1393505 Spirochaeta smaragdinae DSM 11293 9489393 YP_003803026.1 CDS Spirs_1305 NC_014364.1 1393512 1394096 D COGs: COG2059 Chromate transporter ChrA; InterPro IPR003370; KEGG: aoe:Clos_1024 chromate transporter; PFAM: Chromate transporter; SPTR: Chromate transporter; PFAM: Chromate transporter; Chromate transporter 1393512..1394096 Spirochaeta smaragdinae DSM 11293 9489394 YP_003803027.1 CDS Spirs_1306 NC_014364.1 1394097 1394693 D COGs: COG2059 Chromate transporter ChrA; InterPro IPR003370; KEGG: bth:BT_1736 chromate transporter; PFAM: Chromate transporter; SPTR: uncharacterized protein; PFAM: Chromate transporter; Chromate transporter 1394097..1394693 Spirochaeta smaragdinae DSM 11293 9489395 YP_003803028.1 CDS Spirs_1307 NC_014364.1 1394719 1395486 R COGs: COG2122 conserved hypothetical protein; InterPro IPR003374; KEGG: swo:Swol_1439 hypothetical protein; PFAM: ApbE family lipoprotein; SPTR: Conserved hypothetical cytosolic protein; PFAM: ApbE family; ApbE family lipoprotein complement(1394719..1395486) Spirochaeta smaragdinae DSM 11293 9489396 YP_003803029.1 CDS Spirs_1308 NC_014364.1 1395461 1395871 R InterPro IPR017900:IPR018449:IPR001450:IPR017896; KEGG: drm:Dred_0102 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: NIL domain; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Small subunit of acetolactate synthase; 4Fe-4S binding domain; NIL domain; NIL domain-containing protein complement(1395461..1395871) Spirochaeta smaragdinae DSM 11293 9489397 YP_003803030.1 CDS Spirs_1309 NC_014364.1 1395874 1397070 R COGs: COG1900 conserved hypothetical protein; InterPro IPR002708; KEGG: dth:DICTH_0569 domain of unknown function, PFAM: protein of unknown function DUF39; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF39; hypothetical protein complement(1395874..1397070) Spirochaeta smaragdinae DSM 11293 9489398 YP_003803031.1 CDS Spirs_1310 NC_014364.1 1397182 1397619 D COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: tde:TDE1494 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: CheY; PFAM: Response regulator receiver domain; response regulator receiver protein 1397182..1397619 Spirochaeta smaragdinae DSM 11293 9489399 YP_003803032.1 CDS Spirs_1311 NC_014364.1 1397597 1398310 R COGs: COG1379 conserved hypothetical protein; InterPro IPR004013:IPR003141; KEGG: pdi:BDI_1093 metal-dependent phosphoesterase; PFAM: PHP domain protein; SMART: phosphoesterase PHP domain protein; SPTR: phosphoesterase PHP; PFAM: PHP domain; PHP domain-containing protein complement(1397597..1398310) Spirochaeta smaragdinae DSM 11293 9489400 YP_003803033.1 CDS Spirs_1312 NC_014364.1 1398322 1398657 R KEGG: tle:Tlet_1634 hypothetical protein; SPTR: uncharacterized protein; PFAM: DRTGG domain; hypothetical protein complement(1398322..1398657) Spirochaeta smaragdinae DSM 11293 9489401 YP_003803034.1 CDS Spirs_1313 NC_014364.1 1398644 1399603 R COGs: COG2524 transcriptional regulator protein; InterPro IPR000644:IPR003594; KEGG: tna:CTN_1237 inosine-5-monophosphate dehydrogenase-related protein; PFAM: CBS domain containing protein; ATP-binding region ATPase domain protein; SMART: CBS domain containing protein; SPTR: inosine-5-monophosphate dehydrogenase-related protein; PFAM: CBS domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction protein with CBS domains complement(1398644..1399603) Spirochaeta smaragdinae DSM 11293 9489402 YP_003803035.1 CDS Spirs_1314 NC_014364.1 1399719 1400063 D InterPro IPR001398; KEGG: mca:MCA2795 phenylpyruvate tautomerase, PFAM: macrophage migration inhibitory factor family protein; SPTR: phenylpyruvate tautomerase; PFAM: Macrophage migration inhibitory factor (MIF); macrophage migration inhibitory factor family protein 1399719..1400063 Spirochaeta smaragdinae DSM 11293 9489403 YP_003803036.1 CDS Spirs_1315 NC_014364.1 1400068 1400322 R InterPro IPR001387; KEGG: tde:TDE2445 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator complement(1400068..1400322) Spirochaeta smaragdinae DSM 11293 9489404 YP_003803037.1 CDS Spirs_1316 NC_014364.1 1400527 1400877 D COGs: COG1366 anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR002645:IPR003658; KEGG: tde:TDE1122 anti-anti-sigma factor; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: anti-sigma factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist 1400527..1400877 Spirochaeta smaragdinae DSM 11293 9489405 YP_003803038.1 CDS Spirs_1317 NC_014364.1 1400877 1401428 D InterPro IPR003594; KEGG: tde:TDE1121 hypothetical protein; PFAM: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; anti-sigma regulatory factor, serine/threonine protein kinase 1400877..1401428 Spirochaeta smaragdinae DSM 11293 9489406 YP_003803039.1 CDS Spirs_1318 NC_014364.1 1401441 1402592 D KEGG: tde:TDE1128 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1401441..1402592 Spirochaeta smaragdinae DSM 11293 9489407 YP_003803040.1 CDS Spirs_1319 NC_014364.1 1402585 1404735 R COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR003660:IPR003018:IPR010822:IPR001932; KEGG: tde:TDE1123 sigma factor regulatory protein, PFAM: stage II sporulation E family protein; GAF domain protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; GAF domain protein; histidine kinase HAMP region domain protein; SPTR: sigma factor regulatory protein; PFAM: HAMP domain; GAF domain; stage II sporulation protein E (SpoIIE); protein serine phosphatase with GAF(s) sensor(s) complement(1402585..1404735) Spirochaeta smaragdinae DSM 11293 9489408 YP_003803041.1 CDS Spirs_1320 NC_014364.1 1404832 1406073 D COGs: COG0420 DNA repair exonuclease; InterPro IPR004843:IPR004593; KEGG: dfe:Dfer_3506 nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; SPTR: Nuclease SbcCD, D subunit; TIGRFAM: nuclease SbcCD, D subunit; PFAM: Calcineurin-like phosphoesterase; type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD; nuclease SbcCD subunit D 1404832..1406073 Spirochaeta smaragdinae DSM 11293 9489409 YP_003803042.1 CDS Spirs_1321 NC_014364.1 1406070 1409114 D COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: dfe:Dfer_3418 SMC domain protein; PFAM: SMC domain protein; SPTR: SMC domain protein; SMC domain-containing protein 1406070..1409114 Spirochaeta smaragdinae DSM 11293 9489410 YP_003803043.1 CDS Spirs_1322 NC_014364.1 1409111 1410445 D COGs: COG1624 conserved hypothetical protein; InterPro IPR002178:IPR003390; KEGG: caa:Caka_1512 protein of unknown function DUF147; PFAM: protein of unknown function DUF147; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS system IIA component; PFAM: DisA bacterial checkpoint controller nucleotide-binding; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; hypothetical protein 1409111..1410445 Spirochaeta smaragdinae DSM 11293 9489411 YP_003803044.1 CDS Spirs_1323 NC_014364.1 1410465 1410908 R COGs: COG2905 signal-transduction protein containing cAMP-binding and CBS domains; InterPro IPR000644; KEGG: ddf:DEFDS_1443 signal transduction protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein; SPTR: Predicted signal-transduction protein containing cAMP-binding and CBS domains; PFAM: CBS domain; signal transduction protein with CBS domains complement(1410465..1410908) Spirochaeta smaragdinae DSM 11293 9489412 YP_003803045.1 CDS Spirs_1324 NC_014364.1 1410956 1411489 R COGs: COG0742 N6-adenine-specific methylase; InterPro IPR002052:IPR016065:IPR004398; KEGG: tde:TDE1881 methyltransferase, PFAM: protein of unknown function methylase SPTR: methyltransferase, ; TIGRFAM: methyltransferase; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family; methyltransferase complement(1410956..1411489) Spirochaeta smaragdinae DSM 11293 9489413 YP_003803046.1 CDS Spirs_1325 NC_014364.1 1411499 1413622 R COGs: COG1200 RecG-like helicase; InterProIPR019793:IPR011545:IPR001650:IPR004609:IPR 014001:IPR014021; KEGG: tde:TDE2579 ATP-dependent DNA helicase RecG; PFAM: DEAD/DEAH box helicase; helicase; SMART: DEAD-like helicase ; helicase; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: ATP-dependent DNA helicase RecG; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG; ATP-dependent DNA helicase RecG complement(1411499..1413622) Spirochaeta smaragdinae DSM 11293 9489414 YP_003803047.1 CDS Spirs_1326 NC_014364.1 1413635 1414222 R InterPro IPR003425; KEGG: btu:BT0580 integral membrane protein, YggT family; PFAM: protein of unknown function YGGT; SPTR: Yggt family protein; PFAM: YGGT family; hypothetical protein complement(1413635..1414222) Spirochaeta smaragdinae DSM 11293 9489415 YP_003803048.1 CDS Spirs_1327 NC_014364.1 1414242 1417667 R COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR000276:IPR004013:IPR011708:IPR004365:IPR 004805:IPR003141; KEGG: tde:TDE2786 DNA polymerase III subunit alpha; PFAM: DNA polymerase III subunit alpha; PHP domain protein; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: phosphoesterase PHP domain protein; SPTR: DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III subunit alpha; PFAM: Bacterial DNA polymerase III subunit alpha; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc); DNA polymerase III subunit alpha complement(1414242..1417667) Spirochaeta smaragdinae DSM 11293 9489416 YP_003803049.1 CDS Spirs_1328 NC_014364.1 1417730 1418590 R COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR016166; KEGG: tde:TDE0728 FAD-binding protein, PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: FAD-binding protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; molybdopterin dehydrogenase FAD-binding protein complement(1417730..1418590) Spirochaeta smaragdinae DSM 11293 9489417 YP_003803050.1 CDS Spirs_1329 NC_014364.1 1418583 1419059 R COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: tai:Taci_0194 (2Fe-2S)-binding domain protein; PFAM: ferredoxin; [2Fe-2S]-binding domain protein; SPTR: (2Fe-2S)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; ferredoxin complement(1418583..1419059) Spirochaeta smaragdinae DSM 11293 9489418 YP_003803051.1 CDS Spirs_1330 NC_014364.1 1419059 1421116 R COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: tde:TDE0726 aldehyde oxidase and xanthine dehydrogenase family protein; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: aldehyde oxidase and xanthine dehydrogenase family protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein complement(1419059..1421116) Spirochaeta smaragdinae DSM 11293 9489419 YP_003803052.1 CDS Spirs_1331 NC_014364.1 1421113 1422309 R COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: bbr:BB0150 lipopolysaccharide biosynthesis protein; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Strongly similar to Arnb transferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase complement(1421113..1422309) Spirochaeta smaragdinae DSM 11293 9489420 YP_003803053.1 CDS Spirs_1332 NC_014364.1 1422327 1423802 R COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR003869; KEGG: tde:TDE0714 capsular polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein CapD; SPTR: Capsular polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; polysaccharide biosynthesis protein CapD complement(1422327..1423802) Spirochaeta smaragdinae DSM 11293 9489421 YP_003803054.1 CDS Spirs_1333 NC_014364.1 1423795 1424349 R InterPro IPR005825:IPR006645; KEGG: tde:TDE0713 NusG family transcription antitermination protein; PFAM: NGN domain protein; SPTR: transcription antitermination protein, NusG family; PFAM: transcription termination factor nusG; NusG antitermination factor complement(1423795..1424349) Spirochaeta smaragdinae DSM 11293 9489422 YP_003803055.1 CDS Spirs_1334 NC_014364.1 1424476 1424970 D KEGG: coc:Coch_1801 glycoside hydrolase family 25; SPTR: lysophospholipase L1 and related esterases; manually curated; hypothetical protein 1424476..1424970 Spirochaeta smaragdinae DSM 11293 9489423 YP_003803056.1 CDS Spirs_1335 NC_014364.1 1424996 1426825 D InterPro IPR007730; KEGG: tpp:TPASS_0433 acidic repeat protein; PFAM: sporulation domain protein; SPTR: acidic repeat protein; PFAM: sporulation related domain; sporulation domain-containing protein 1424996..1426825 Spirochaeta smaragdinae DSM 11293 9489424 YP_003803057.1 CDS Spirs_1336 NC_014364.1 1426835 1428946 D COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR018239:IPR013839:IPR004150:IPR004149:IPR 001357:IPR001679:IPR013840:IPR003583; KEGG: lic:LIC13282 NAD dependent DNA ligase; PFAM: NAD-dependent DNA ligase adenylation; NAD-dependent DNA ligase OB-fold; zinc-finger NAD-dependent DNA ligase C4-type; BRCT domain protein; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase ; DNA-binding protein; BRCT domain protein; SPTR: DNA ligase; TIGRFAM: DNA ligase, NAD-dependent; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent; DNA ligase, NAD-dependent 1426835..1428946 Spirochaeta smaragdinae DSM 11293 9489425 YP_003803058.1 CDS Spirs_1337 NC_014364.1 1428946 1429704 D InterPro IPR008884; KEGG: azc:AZC_1519 macrocin-O-methyltransferase domain-containing protein; PFAM: macrocin-O-methyltransferase; SPTR: Macrocin-O-methyltransferase domain protein; PFAM: Macrocin-O-methyltransferase (TylF); macrocin-O-methyltransferase 1428946..1429704 Spirochaeta smaragdinae DSM 11293 9489426 YP_003803059.1 CDS Spirs_1338 NC_014364.1 1429729 1430073 R KEGG: sil:SPO1219 phage integrase family site specific recombinase; SPTR: transposase; hypothetical protein complement(1429729..1430073) Spirochaeta smaragdinae DSM 11293 9489427 YP_003803060.1 CDS Spirs_1339 NC_014364.1 1430058 1431683 R InterPro IPR013229; KEGG: tga:TGAM_0982 hypothetical protein, S-layer-like related; PFAM: PEGA domain protein; SPTR: PEGA domain protein; PFAM: PEGA domain; PEGA domain-containing protein complement(1430058..1431683) Spirochaeta smaragdinae DSM 11293 9489428 YP_003803061.1 CDS Spirs_1340 NC_014364.1 1431750 1432313 D KEGG: tde:TDE0066 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1431750..1432313 Spirochaeta smaragdinae DSM 11293 9489429 YP_003803062.1 CDS Spirs_1341 NC_014364.1 1432325 1432768 D COGs: COG1430 conserved hypothetical protein; InterPro IPR003795; KEGG: rxy:Rxyl_2570 hypothetical protein; PFAM: protein of unknown function DUF192; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1430; hypothetical protein 1432325..1432768 Spirochaeta smaragdinae DSM 11293 9489430 YP_003803063.1 CDS Spirs_1342 NC_014364.1 1432789 1433013 R InterPro IPR003761; KEGG: tde:TDE2066 exodeoxyribonuclease VII, small subunit; PFAM: exonuclease VII small subunit; SPTR: exodeoxyribonuclease VII small subunit; PFAM: exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII small subunit; exonuclease VII small subunit complement(1432789..1433013) Spirochaeta smaragdinae DSM 11293 9489431 YP_003803064.1 CDS Spirs_1343 NC_014364.1 1433000 1434223 R COGs: COG1570 exonuclease VII large subunit; InterPro IPR004365:IPR020579:IPR003753; KEGG: tde:TDE1017 exodeoxyribonuclease VII large subunit; PFAM: exonuclease VII, large subunit-like; nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: exodeoxyribonuclease VII; SPTR: exodeoxyribonuclease 7 large subunit; TIGRFAM: exodeoxyribonuclease VII large subunit; PFAM: exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII large subunit; exodeoxyribonuclease VII large subunit complement(1433000..1434223) Spirochaeta smaragdinae DSM 11293 9489432 YP_003803065.1 CDS Spirs_1344 NC_014364.1 1434273 1434866 R InterPro IPR013105:IPR019734:IPR013026; KEGG: min:Minf_1004 TPR repeats containing protein; PFAM: Tetratricopeptide TPR_2 repeat protein; SPTR: TPR repeat, MamA; PFAM: Tetratricopeptide repeat; hypothetical protein complement(1434273..1434866) Spirochaeta smaragdinae DSM 11293 9489433 YP_003803066.1 CDS Spirs_1345 NC_014364.1 1434924 1436585 D COGs: COG0366 glycosidase; InterPro IPR006047:IPR006589; KEGG: lbf:LBF_3272 glycosidase; PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: glycosidase; PFAM: alpha amylase, C-terminal all-beta domain; alpha amylase, catalytic domain; alpha amylase catalytic subunit 1434924..1436585 Spirochaeta smaragdinae DSM 11293 9489434 YP_003803067.1 CDS Spirs_1346 NC_014364.1 1436596 1437195 R COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mac:MA2167 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: Iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase complement(1436596..1437195) Spirochaeta smaragdinae DSM 11293 9489435 YP_003803068.1 CDS Spirs_1347 NC_014364.1 1437235 1437954 R COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: bcl:ABC2722 transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; manually curated; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(1437235..1437954) Spirochaeta smaragdinae DSM 11293 9489436 YP_003803069.1 CDS Spirs_1348 NC_014364.1 1438145 1439086 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: gym:GYMC10_3581 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 1438145..1439086 Spirochaeta smaragdinae DSM 11293 9489437 YP_003803070.1 CDS Spirs_1349 NC_014364.1 1439092 1440096 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR002139:IPR011611; KEGG: ctc:CTC00909 ribokinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: ribokinase; PfkB domain-containing protein 1439092..1440096 Spirochaeta smaragdinae DSM 11293 9489438 YP_003803071.1 CDS Spirs_1350 NC_014364.1 1440105 1440746 D COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR018506:IPR001347; KEGG: apv:Apar_1282 sugar isomerase (SIS); PFAM: sugar isomerase (SIS); PRIAM: Arabinose-5-phosphate isomerase; SPTR: uncharacterized protein; PFAM: SIS domain; Arabinose-5-phosphate isomerase 1440105..1440746 Spirochaeta smaragdinae DSM 11293 9489439 YP_003803072.1 CDS Spirs_1351 NC_014364.1 1440850 1441698 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: tle:Tlet_0020 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: extracellular solute-binding protein family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein 1440850..1441698 Spirochaeta smaragdinae DSM 11293 9489440 YP_003803073.1 CDS Spirs_1352 NC_014364.1 1441768 1442514 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: tle:Tlet_0021 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; manually curated; PFAM: ABC transporter; ABC transporter 1441768..1442514 Spirochaeta smaragdinae DSM 11293 9489441 YP_003803074.1 CDS Spirs_1353 NC_014364.1 1442531 1443181 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: tle:Tlet_0022 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 1442531..1443181 Spirochaeta smaragdinae DSM 11293 9489442 YP_003803075.1 CDS Spirs_1354 NC_014364.1 1443185 1443841 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: tle:Tlet_0023 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 1443185..1443841 Spirochaeta smaragdinae DSM 11293 9489443 YP_003803076.1 CDS Spirs_1355 NC_014364.1 1443857 1444972 D COGs: COG0787 alanine racemase; InterPro IPR020622:IPR000821:IPR001608:IPR011079; KEGG: tde:TDE1095 alanine racemase; PFAM: alanine racemase domain protein; PRIAM: alanine racemase; SPTR: alanine racemase; TIGRFAM: alanine racemase; PFAM: alanine racemase, C-terminal domain; alanine racemase, N-terminal domain; TIGRFAM: alanine racemase; alanine racemase 1443857..1444972 Spirochaeta smaragdinae DSM 11293 9489444 YP_003803077.1 CDS Spirs_1356 NC_014364.1 1445018 1446202 D COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: tle:Tlet_0024 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II; PFAM: Aminotransferase class I and II; class I and II aminotransferase 1445018..1446202 Spirochaeta smaragdinae DSM 11293 9489445 YP_003803078.1 CDS Spirs_1357 NC_014364.1 1446376 1447395 D COGs: COG3641 membrane protein toxin regulator; KEGG: amt:Amet_0021 phosphotransferase system, EIIC; SPTR: phosphotransferase system, EIIC; phosphotransferase system, EIIC 1446376..1447395 Spirochaeta smaragdinae DSM 11293 9489446 YP_003803079.1 CDS Spirs_1358 NC_014364.1 1447407 1447613 D COGs: COG4895 conserved hypothetical protein; InterPro IPR019240; KEGG: mmh:Mmah_0125 protein of unknown function DUF2196; PFAM: protein of unknown function DUF2196; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2196); hypothetical protein 1447407..1447613 Spirochaeta smaragdinae DSM 11293 9489447 YP_003803080.1 CDS Spirs_1359 NC_014364.1 1447650 1449449 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR004010:IPR003660:IPR011495; KEGG: dvl:Dvul_0613 PAS/PAC sensor protein; PFAM: histidine kinase dimerisation/phosphoacceptor; histidine kinase HAMP region domain protein; Cache domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: histidine kinase; Cache domain; HAMP domain; signal transduction histidine kinase 1447650..1449449 Spirochaeta smaragdinae DSM 11293 9489448 YP_003803081.1 CDS Spirs_1360 NC_014364.1 1449446 1449982 D COGs: COG3542 conserved hypothetical protein; InterPro IPR009327; KEGG: sma:SAV_4169 hypothetical protein; PFAM: protein of unknown function DUF985; SPTR: uncharacterized protein; PFAM: Cupin superfamily (DUF985); hypothetical protein 1449446..1449982 Spirochaeta smaragdinae DSM 11293 9489449 YP_003803082.1 CDS Spirs_1361 NC_014364.1 1450035 1450313 D KEGG: cho:Chro.20280 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1450035..1450313 Spirochaeta smaragdinae DSM 11293 9489450 YP_003803083.1 CDS Spirs_1362 NC_014364.1 1450335 1451510 D COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR006680:IPR003764; KEGG: bre:BRE_151 N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; N-acetylglucosamine-6-phosphate deacetylase 1450335..1451510 Spirochaeta smaragdinae DSM 11293 9489451 YP_003803084.1 CDS Spirs_1363 NC_014364.1 1451507 1453222 D COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594:IPR005467; KEGG: bha:BH3447 two-component sensor histidine kinase; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: histidine kinase; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 1451507..1453222 Spirochaeta smaragdinae DSM 11293 9489452 YP_003803085.1 CDS Spirs_1364 NC_014364.1 1453222 1454004 D COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR018062:IPR020449:IPR001789:IPR000005:IPR 018060; KEGG: clo:HMPREF0868_0308 response regulator receiver domain protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: response regulator receiver; Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1453222..1454004 Spirochaeta smaragdinae DSM 11293 9489453 YP_003803086.1 CDS Spirs_1365 NC_014364.1 1453957 1454544 R COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402; KEGG: tle:Tlet_2032 HAD family hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; HAD-superfamily hydrolase complement(1453957..1454544) Spirochaeta smaragdinae DSM 11293 9489454 YP_003803087.1 CDS Spirs_1366 NC_014364.1 1454548 1455387 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tle:Tlet_0131 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporter inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1454548..1455387) Spirochaeta smaragdinae DSM 11293 9489455 YP_003803088.1 CDS Spirs_1367 NC_014364.1 1455387 1456385 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tle:Tlet_0132 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporter inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1455387..1456385) Spirochaeta smaragdinae DSM 11293 9489456 YP_003803089.1 CDS Spirs_1368 NC_014364.1 1456390 1457691 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: tle:Tlet_0133 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(1456390..1457691) Spirochaeta smaragdinae DSM 11293 9489457 YP_003803090.1 CDS Spirs_1369 NC_014364.1 1457688 1457936 R KEGG: mgl:MGL_0791 hypothetical protein; SPTR: uncharacterized protein Sb07g026310; hypothetical protein complement(1457688..1457936) Spirochaeta smaragdinae DSM 11293 9489458 YP_003803091.1 CDS Spirs_1370 NC_014364.1 1457998 1458663 D KEGG: bgl:bglu_1g23870 transposase; SPTR: uncharacterized protein; hypothetical protein 1457998..1458663 Spirochaeta smaragdinae DSM 11293 9489459 YP_003803092.1 CDS Spirs_1371 NC_014364.1 1458663 1459115 D KEGG: mta:Moth_1697 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1458663..1459115 Spirochaeta smaragdinae DSM 11293 9489460 YP_003803093.1 CDS Spirs_1372 NC_014364.1 1459143 1459997 R COGs: COG0349 ribonuclease D; InterPro IPR002562:IPR002121; KEGG: dat:HRM2_37670 Rnd; PFAM: 3'-5' exonuclease; HRDC domain protein; SMART: 3'-5' exonuclease; SPTR: Rnd; PFAM: 3'-5' exonuclease; HRDC domain; 3'-5' exonuclease complement(1459143..1459997) Spirochaeta smaragdinae DSM 11293 9489461 YP_003803094.1 CDS Spirs_1373 NC_014364.1 1460310 1461059 D COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: fpl:Ferp_0222 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain; type 11 methyltransferase 1460310..1461059 Spirochaeta smaragdinae DSM 11293 9489462 YP_003803095.1 CDS Spirs_1374 NC_014364.1 1461056 1462234 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: mac:MA2153 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 1461056..1462234 Spirochaeta smaragdinae DSM 11293 9489463 YP_003803096.1 CDS Spirs_1375 NC_014364.1 1462227 1463291 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: mba:Mbar_A0466 Fe(III) dicitrate ABC transporter permease; PFAM: transporter permease; SPTR: Fe(III) dicitrate ABC transporter permease; PFAM: FecCD transport family; transporter permease 1462227..1463291 Spirochaeta smaragdinae DSM 11293 9489464 YP_003803097.1 CDS Spirs_1376 NC_014364.1 1463291 1464061 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR003439:IPR003593; KEGG: mba:Mbar_A0465 Fe(III) dicitrate ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Fe(III) dicitrate ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 1463291..1464061 Spirochaeta smaragdinae DSM 11293 9489465 YP_003803098.1 CDS Spirs_1377 NC_014364.1 1464071 1464817 R COGs: COG1878 metal-dependent hydrolase; InterPro IPR007325; KEGG: lme:LEUM_0115 metal-dependent hydrolase; PFAM: cyclase family protein; SPTR: Predicted metal-dependent hydrolase; PFAM: cyclase; cyclase family protein complement(1464071..1464817) Spirochaeta smaragdinae DSM 11293 9489466 YP_003803099.1 CDS Spirs_1378 NC_014364.1 1465038 1465742 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: eel:EUBELI_01503 two-component system, OmpR family, phosphate regulon response regulator OmpR; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; SPTR: Two component transcriptional regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator complement(1465038..1465742) Spirochaeta smaragdinae DSM 11293 9489467 YP_003803100.1 CDS Spirs_1379 NC_014364.1 1465711 1467894 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003661:IPR003594:IPR001789:IPR 005467; KEGG: fno:Fnod_1277 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; histidine kinase complement(1465711..1467894) Spirochaeta smaragdinae DSM 11293 9489468 YP_003803101.1 CDS Spirs_1380 NC_014364.1 1468044 1468406 D KEGG: gga:429198 fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus); SPTR: uncharacterized protein; hypothetical protein 1468044..1468406 Spirochaeta smaragdinae DSM 11293 9489469 YP_003803102.1 CDS Spirs_1381 NC_014364.1 1468426 1470456 D KEGG: azl:AZL_b05690 major facilitator superfamily MFS-1; SPTR: 2-polyprenyl-6-methoxyphenol hydroxylase-like oxidoreductase; hypothetical protein 1468426..1470456 Spirochaeta smaragdinae DSM 11293 9489470 YP_003803103.1 CDS Spirs_1382 NC_014364.1 1470590 1471441 D COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: pam:PANA_2380 FbaA; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: 5-dehydro-2-deoxyphosphogluconate aldolase; SPTR: FbaA; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase 1470590..1471441 Spirochaeta smaragdinae DSM 11293 9489471 YP_003803104.1 CDS Spirs_1383 NC_014364.1 1471466 1472428 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002139:IPR011611; KEGG: cro:ROD_12821 sugar kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 1471466..1472428 Spirochaeta smaragdinae DSM 11293 9489472 YP_003803105.1 CDS Spirs_1384 NC_014364.1 1472539 1473759 R COGs: COG0498 threonine synthase; InterPro IPR001926; KEGG: kol:Kole_2075 threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: threonine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; pyridoxal-5'-phosphate-dependent protein subunit beta complement(1472539..1473759) Spirochaeta smaragdinae DSM 11293 9489473 YP_003803106.1 CDS Spirs_1385 NC_014364.1 1473852 1475315 R COGs: COG0031 cysteine synthase; InterPro IPR001926; KEGG: pmo:Pmob_1727 pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: pyridoxal-5'-phosphate-dependent protein subunit beta; PFAM: pyridoxal-phosphate dependent enzyme; pyridoxal-5'-phosphate-dependent protein subunit beta complement(1473852..1475315) Spirochaeta smaragdinae DSM 11293 9489474 YP_003803107.1 CDS Spirs_1386 NC_014364.1 1475658 1478765 D COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterProIPR018247:IPR017900:IPR000759:IPR013027:IPR 017701:IPR017896; KEGG: ppr:PBPRA1943 selenate reductase subunit YgfK; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Predicted oxidoreductase, Fe-S subunit; TIGRFAM: selenate reductase YgfK; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: selenate reductase, YgfK subunit; selenate reductase YgfK 1475658..1478765 Spirochaeta smaragdinae DSM 11293 9489475 YP_003803108.1 CDS Spirs_1387 NC_014364.1 1478769 1480103 D COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680:IPR017700; KEGG: hmo:HM1_2652 amidohydrolase; PFAM: amidohydrolase; PRIAM: S-adenosylhomocysteine deaminase; SPTR: protein SsnA; TIGRFAM: selenium metabolism protein SsnA; PFAM: Amidohydrolase family; TIGRFAM: selenium metabolism protein SsnA; selenium metabolism protein SsnA 1478769..1480103 Spirochaeta smaragdinae DSM 11293 9489476 YP_003803109.1 CDS Spirs_1388 NC_014364.1 1480142 1481362 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261:IPR002933:IPR011650:IPR017706; KEGG: kol:Kole_2070 M20/DapE family protein YgeY; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase; TIGRFAM: M20/DapE family protein YgeY; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: selenium metabolism hydrolase; M20/DapE family protein YgeY; M20/DapE family protein YgeY 1480142..1481362 Spirochaeta smaragdinae DSM 11293 9489477 YP_003803110.1 CDS Spirs_1389 NC_014364.1 1481461 1483596 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: bhy:BHWA1_00062 aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL S; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: xanthine dehydrogenase, molybdenum-binding subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein 1481461..1483596 Spirochaeta smaragdinae DSM 11293 9489478 YP_003803111.1 CDS Spirs_1390 NC_014364.1 1483593 1484066 D COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: ppd:Ppro_1445 2Fe-2S iron-sulfur cluster binding domain-containing protein; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: (2Fe-2S)-binding domain protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein 1483593..1484066 Spirochaeta smaragdinae DSM 11293 9489479 YP_003803112.1 CDS Spirs_1391 NC_014364.1 1484060 1484917 D COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR016166; KEGG: ppr:PBPRA1939 dehydrogenase; PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: CoxM; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; molybdopterin dehydrogenase FAD-binding protein 1484060..1484917 Spirochaeta smaragdinae DSM 11293 9489480 YP_003803113.1 CDS Spirs_1392 NC_014364.1 1484920 1486281 D COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: str:Sterm_1669 S-adenosylhomocysteine deaminase; PFAM: amidohydrolase; SPTR: S-adenosylhomocysteine deaminase; PFAM: Amidohydrolase family; amidohydrolase 1484920..1486281 Spirochaeta smaragdinae DSM 11293 9489481 YP_003803114.1 CDS Spirs_1393 NC_014364.1 1486292 1487083 D COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR016166; KEGG: ecg:E2348C_3133 selenate reductase subunit YgfM; PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: Predicted oxidoreductase; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; TIGRFAM: probable selenate reductase, FAD-binding subunit; molybdopterin dehydrogenase FAD-binding protein 1486292..1487083 Spirochaeta smaragdinae DSM 11293 9489482 YP_003803115.1 CDS Spirs_1394 NC_014364.1 1487089 1489959 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR002888:IPR000674:IPR008274:IPR017699; KEGG: ppr:PBPRA1932 selenate reductase subunit YgfN; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; [2Fe-2S]-binding domain protein; SPTR: dehydrogenase; TIGRFAM: selenate reductase, molybdenum-binding subunit; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; [2Fe-2S] binding domain; TIGRFAM: probable selenate reductase, molybdenum-binding subunit; selenate reductase, molybdenum-binding subunit 1487089..1489959 Spirochaeta smaragdinae DSM 11293 9489483 YP_003803116.1 CDS Spirs_1395 NC_014364.1 1490054 1491250 D COGs: COG0078 ornithine carbamoyltransferase; InterProIPR002082:IPR006130:IPR006132:IPR006131:IPR 017702; KEGG: apr:Apre_1433 carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; SPTR: Probable carbamoyltransferase YgeW; TIGRFAM: carbamoyltransferase YgeW; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: probable carbamoyltransferase YgeW; carbamoyltransferase YgeW 1490054..1491250 Spirochaeta smaragdinae DSM 11293 9489484 YP_003803117.1 CDS Spirs_1396 NC_014364.1 1491471 1492799 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: csc:Csac_0126 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1491471..1492799 Spirochaeta smaragdinae DSM 11293 9489485 YP_003803118.1 CDS Spirs_1397 NC_014364.1 1492816 1493703 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: gym:GYMC10_2805 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1492816..1493703 Spirochaeta smaragdinae DSM 11293 9489486 YP_003803119.1 CDS Spirs_1398 NC_014364.1 1493715 1494557 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_13120 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1493715..1494557 Spirochaeta smaragdinae DSM 11293 9489487 YP_003803120.1 CDS Spirs_1399 NC_014364.1 1494577 1495341 D COGs: COG3142 Uncharacterized protein involved in copper resistance; InterPro IPR005627; KEGG: mmu:66388 cutC copper transporter homolog (E.coli); PFAM: CutC family protein; SPTR: uncharacterized protein Cutc; PFAM: CutC family; CutC family protein 1494577..1495341 Spirochaeta smaragdinae DSM 11293 9489488 YP_003803121.1 CDS Spirs_1400 NC_014364.1 1495363 1496535 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000835:IPR000600; KEGG: tpd:Teth39_2053 ROK family protein; PFAM: ROK family protein; regulatory protein MarR; SPTR: ROK family protein; PFAM: ROK family; MarR family; ROK family protein 1495363..1496535 Spirochaeta smaragdinae DSM 11293 9489489 YP_003803122.1 CDS Spirs_1401 NC_014364.1 1496569 1498065 D COGs: COG5476 conserved hypothetical protein; InterPro IPR015995:IPR010799:IPR009197; KEGG: tde:TDE1696 hypothetical protein; PFAM: Microcystin LR degradation protein MlrC-like; MlrC domain protein; SPTR: MlrC domain protein; PFAM: MlrC C-terminus; protein of unknown function (DUF1485); Microcystin LR degradation protein MlrC 1496569..1498065 Spirochaeta smaragdinae DSM 11293 9489490 YP_003803123.1 CDS Spirs_1402 NC_014364.1 1498162 1499673 D COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR015875:IPR001093:IPR000644:IPR018529; KEGG: clo:HMPREF0868_0954 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; CBS domain containing protein; SPTR: IMP dehydrogenase/GMP reductase; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase; IMP dehydrogenase/GMP reductase 1498162..1499673 Spirochaeta smaragdinae DSM 11293 9489491 YP_003803124.1 CDS Spirs_1403 NC_014364.1 1499696 1501279 R COGs: COG3920 Signal transduction histidine kinase; InterProIPR018771:IPR013656:IPR011495:IPR003594:IPR 000014; KEGG: cts:Ctha_0145 signal transduction histidine kinase; PFAM: transcriptional regulator, histidine kinase sensor-like; hypothetical protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Predicted histidine kinase sensor domain; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase complement(1499696..1501279) Spirochaeta smaragdinae DSM 11293 9489492 YP_003803125.1 CDS Spirs_1404 NC_014364.1 1501498 1502178 R KEGG: tde:TDE2433 treponemal membrane protein, SPTR: Treponemal membrane protein; treponemal membrane protein complement(1501498..1502178) Spirochaeta smaragdinae DSM 11293 9489493 YP_003803126.1 CDS Spirs_1405 NC_014364.1 1502175 1502906 R KEGG: lma:LmjF27.0240 kinetoplast-associated protein-like protein; SPTR: Kinetoplast-associated protein-like protein; hypothetical protein complement(1502175..1502906) Spirochaeta smaragdinae DSM 11293 9489494 YP_003803127.1 CDS Spirs_1406 NC_014364.1 1503174 1503380 D KEGG: aap:NT05HA_1711 hypothetical protein; SPTR: membrane protein; hypothetical protein 1503174..1503380 Spirochaeta smaragdinae DSM 11293 9489495 YP_003803128.1 CDS Spirs_1407 NC_014364.1 1503516 1504589 D COGs: COG0760 Parvulin-like peptidyl-prolyl isomerase; InterPro IPR000297:IPR015391; KEGG: sfu:Sfum_0568 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SurA domain; SPTR: PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; PpiC-type peptidyl-prolyl cis-trans isomerase 1503516..1504589 Spirochaeta smaragdinae DSM 11293 9489496 YP_003803129.1 CDS Spirs_1408 NC_014364.1 1504691 1506598 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: tde:TDE2783 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(1504691..1506598) Spirochaeta smaragdinae DSM 11293 9489497 YP_003803130.1 CDS Spirs_1409 NC_014364.1 1506746 1507099 D COGs: COG3118 thioredoxin domain-containing protein; InterProIPR017937:IPR006662:IPR013766:IPR005746:IPR 017936; KEGG: bvu:BVU_1309 thioredoxin; PFAM: thioredoxin domain; SPTR: thioredoxin; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin; thioredoxin 1506746..1507099 Spirochaeta smaragdinae DSM 11293 9489498 YP_003803131.1 CDS Spirs_1410 NC_014364.1 1507130 1507708 R COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: dhd:Dhaf_2179 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: TetR family transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(1507130..1507708) Spirochaeta smaragdinae DSM 11293 9489499 YP_003803132.1 CDS Spirs_1411 NC_014364.1 1507782 1509449 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR001789:IPR003018:IPR003594:IPR 005467; KEGG: glo:Glov_0071 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; GAF domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; multi-sensor signal transduction histidine kinase 1507782..1509449 Spirochaeta smaragdinae DSM 11293 9489500 YP_003803133.1 CDS Spirs_1412 NC_014364.1 1509489 1510514 D COGs: COG1975 xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR003777; KEGG: ttr:Tter_2236 protein of unknown function DUF182; PFAM: protein of unknown function DUF182; SPTR: XdhC/CoxI family protein; PFAM: XdhC and CoxI family; hypothetical protein 1509489..1510514 Spirochaeta smaragdinae DSM 11293 9489501 YP_003803134.1 CDS Spirs_1413 NC_014364.1 1510511 1511860 D COGs: COG0548 acetylglutamate kinase; InterPro IPR000209:IPR001048:IPR000182:IPR010167; KEGG: fsu:Fisuc_1504 amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; SPTR: Amino-acid N-acetyltransferase; TIGRFAM: amino-acid N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; amino-acid N-acetyltransferase 1510511..1511860 Spirochaeta smaragdinae DSM 11293 9489502 YP_003803135.1 CDS Spirs_1414 NC_014364.1 1511904 1512644 R COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_0379 cobalt transporter; PFAM: cobalt transporter; SPTR: Cobalt transporter; PFAM: Cobalt transporter; cobalt transporter complement(1511904..1512644) Spirochaeta smaragdinae DSM 11293 9489503 YP_003803136.1 CDS Spirs_1415 NC_014364.1 1512631 1513383 R COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003439:IPR003593; KEGG: sfu:Sfum_1750 cobalt ABC transporter ATPase; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: Cobalt ABC transporter ATPase; PFAM: ABC transporter; TIGRFAM: cobalt transporter ATP-binding subunit; ABC transporter complement(1512631..1513383) Spirochaeta smaragdinae DSM 11293 9489504 YP_003803137.1 CDS Spirs_1416 NC_014364.1 1513394 1513969 R COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: dat:HRM2_26930 BioY family protein; PFAM: BioY protein; SPTR: BioY family protein; PFAM: BioY family; BioY protein complement(1513394..1513969) Spirochaeta smaragdinae DSM 11293 9489505 YP_003803138.1 CDS Spirs_1417 NC_014364.1 1513986 1514924 R COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR013196:IPR004143:IPR003142:IPR004408; KEGG: hmu:Hmuk_2576 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; hypothetical protein; biotin protein ligase domain protein; SPTR: Biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: BirA biotin operon repressor domain; birA, biotin-[acetyl-CoA-carboxylase] ligase region; biotin/acetyl-CoA-carboxylase ligase complement(1513986..1514924) Spirochaeta smaragdinae DSM 11293 9489506 YP_003803139.1 CDS Spirs_1418 NC_014364.1 1514974 1515342 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsy:DSY4941 hypothetical protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(1514974..1515342) Spirochaeta smaragdinae DSM 11293 9489507 YP_003803140.1 CDS Spirs_1419 NC_014364.1 1515378 1518080 R COGs: COG3852 Signal transduction histidine kinase nitrogen specific; InterProIPR000834:IPR004358:IPR003660:IPR013767:IPR 003661:IPR003594:IPR001789:IPR000014:IPR005467; KEGG: dal:Dalk_1692 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; nitrogen specific signal transduction histidine kinase NtrB complement(1515378..1518080) Spirochaeta smaragdinae DSM 11293 9489508 YP_003803141.1 CDS Spirs_1420 NC_014364.1 1518077 1518508 R KEGG: sth:STH2037 nitrogen fixation protein; SPTR: nitrogen fixation protein; hypothetical protein complement(1518077..1518508) Spirochaeta smaragdinae DSM 11293 9489509 YP_003803142.1 CDS Spirs_1421 NC_014364.1 1518522 1519742 R COGs: COG0520 Selenocysteine lyase; InterPro IPR020578:IPR000192; KEGG: sufS; cysteine desulfurase SufS; PFAM: aminotransferase class V; SPTR: cysteine desulfurase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; class V aminotransferase complement(1518522..1519742) Spirochaeta smaragdinae DSM 11293 9489510 YP_003803143.1 CDS Spirs_1422 NC_014364.1 1519739 1520926 R COGs: COG0626 cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: tte:TTE1585 cystathionine beta-lyase/cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: cystathionine beta-lyases/cystathionine gamma-synthases; PFAM: Cys/Met metabolism PLP-dependent enzyme; Cys/Met metabolism pyridoxal-phosphate-dependent protein complement(1519739..1520926) Spirochaeta smaragdinae DSM 11293 9489511 YP_003803144.1 CDS Spirs_1423 NC_014364.1 1520923 1521972 R COGs: COG0182 translation initiation factor 2subunit beta eIF-2B alpha/beta/delta family; InterPro IPR000649:IPR005251:IPR011559; KEGG: tpd:Teth39_0879 aIF-2BI family translation initiation factor; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: translation initiation factor, aIF-2BI family; TIGRFAM: translation initiation factor, aIF-2BI family; eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; S-methyl-5-thioribose-1-phosphate isomerase; translation initiation factor, aIF-2BI family complement(1520923..1521972) Spirochaeta smaragdinae DSM 11293 9489512 YP_003803145.1 CDS Spirs_1424 NC_014364.1 1522009 1523298 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: adg:Adeg_0967 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(1522009..1523298) Spirochaeta smaragdinae DSM 11293 9489513 YP_003803146.1 CDS Spirs_1425 NC_014364.1 1523422 1524057 D COGs: COG1335 amidase related to nicotinamidase; InterPro IPR000868; KEGG: rmr:Rmar_0822 nicotinamidase; PFAM: isochorismatase hydrolase; PRIAM: nicotinamidase; SPTR: Pyrazinamidase/nicotinamidase; manually curated; PFAM: Isochorismatase family; nicotinamidase 1523422..1524057 Spirochaeta smaragdinae DSM 11293 9489514 YP_003803147.1 CDS Spirs_1426 NC_014364.1 1524054 1525550 D COGs: COG0364 glucose-6-phosphate 1-dehydrogenase; InterPro IPR019796:IPR001282; KEGG: dal:Dalk_3007 glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase; PRIAM: glucose-6-phosphate dehydrogenase; SPTR: glucose-6-phosphate 1-dehydrogenase; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; PFAM: glucose-6-phosphate dehydrogenase, C-terminal domain; glucose-6-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glucose-6-phosphate 1-dehydrogenase; glucose-6-phosphate 1-dehydrogenase 1524054..1525550 Spirochaeta smaragdinae DSM 11293 9489515 YP_003803148.1 CDS Spirs_1427 NC_014364.1 1525547 1526266 D COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; KEGG: sru:SRU_0864 6-phosphogluconolactonase; SPTR: 6-phosphogluconolactonase; TIGRFAM: 6-phosphogluconolactonase; 6-phosphogluconolactonase 1525547..1526266 Spirochaeta smaragdinae DSM 11293 9489516 YP_003803149.1 CDS Spirs_1428 NC_014364.1 1526263 1526601 R KEGG: cbc:CbuK_0944 hypothetical cytosolic protein; SPTR: Hypothetical cytosolic protein; PFAM: Domain of unknown function (DUF1820); hypothetical protein complement(1526263..1526601) Spirochaeta smaragdinae DSM 11293 9489517 YP_003803150.1 CDS Spirs_1429 NC_014364.1 1526660 1527259 R COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: cbc:CbuK_0473 MarC family integral membrane protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: MarC family integral membrane protein; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427; multiple antibiotic resistance (MarC)-like protein complement(1526660..1527259) Spirochaeta smaragdinae DSM 11293 9489518 YP_003803151.1 CDS Spirs_1430 NC_014364.1 1527266 1529032 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: kol:Kole_1133 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: metal dependent phosphohydrolase; PFAM: HD domain; metal dependent phosphohydrolase complement(1527266..1529032) Spirochaeta smaragdinae DSM 11293 9489519 YP_003803152.1 CDS Spirs_1431 NC_014364.1 1529040 1530047 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sus:acid_1343 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase domain protein; manually curated; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(1529040..1530047) Spirochaeta smaragdinae DSM 11293 9489520 YP_003803153.1 CDS Spirs_1432 NC_014364.1 1530136 1530357 D KEGG: bba:Bd1502 cAMP-dependent protein kinase; SPTR: cAMP-dependent protein kinase; hypothetical protein 1530136..1530357 Spirochaeta smaragdinae DSM 11293 9489521 YP_003803154.1 CDS Spirs_1433 NC_014364.1 1530354 1531943 D COGs: COG0540 aspartate carbamoyltransferase catalytic chain; InterProIPR006130:IPR002082:IPR006132:IPR006131:IPR 020545:IPR020542; KEGG: tde:TDE0129 bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate carbamoyltransferase regulatory subunit-like; PRIAM: aspartate carbamoyltransferase; SPTR: protein pyrBI; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; aspartate carbamoyltransferase regulatory chain, metal binding domain; aspartate carbamoyltransferase regulatory chain, allosteric domain; TIGRFAM: aspartate carbamoyltransferase, regulatory subunit; aspartate carbamoyltransferase; aspartate carbamoyltransferase 1530354..1531943 Spirochaeta smaragdinae DSM 11293 9489522 YP_003803155.1 CDS Spirs_1434 NC_014364.1 1531940 1532635 D COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836:IPR004467; KEGG: tde:TDE1001 orotate phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: orotate phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase; orotate phosphoribosyltransferase 1531940..1532635 Spirochaeta smaragdinae DSM 11293 9489523 YP_003803156.1 CDS Spirs_1435 NC_014364.1 1532637 1533530 D COGs: COG0284 orotidine-5'-phosphate decarboxylase; InterPro IPR001754:IPR011995; KEGG: tde:TDE2110 orotidine 5'-phosphate decarboxylase; PFAM: orotidine 5'-phosphate decarboxylase; PRIAM: orotidine-5'-phosphate decarboxylase; SPTR: orotidine 5'-phosphate decarboxylase; TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2; orotidine 5'-phosphate decarboxylase 1532637..1533530 Spirochaeta smaragdinae DSM 11293 9489524 YP_003803157.1 CDS Spirs_1436 NC_014364.1 1533520 1535313 D COGs: COG0167 dihydroorotate dehydrogenase; InterProIPR001221:IPR012135:IPR008333:IPR001433:IPR 005720:IPR017927; KEGG: tde:TDE0982 dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; PFAM: dihydroorotate oxidase; oxidoreductase FAD-binding domain protein; oxidoreductase FAD/NAD(P)-binding domain protein; SPTR: dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein; dihydroorotate dehydrogenase 1533520..1535313 Spirochaeta smaragdinae DSM 11293 9489525 YP_003803158.1 CDS Spirs_1437 NC_014364.1 1535303 1536415 D COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; KEGG: tde:TDE2107 dihydroorotase, SPTR: dihydroorotase; dihydroorotase 1535303..1536415 Spirochaeta smaragdinae DSM 11293 9489526 YP_003803159.1 CDS Spirs_1438 NC_014364.1 1536457 1537809 D COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: aoe:Clos_1966 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein 1536457..1537809 Spirochaeta smaragdinae DSM 11293 9489527 YP_003803160.1 CDS Spirs_1439 NC_014364.1 1537862 1539031 D COGs: COG0462 phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: mmw:Mmwyl1_1169 ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase; PRIAM: ribose-phosphate diphosphokinase; SPTR: ribose-phosphate pyrophosphokinase; TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase; ribose-phosphate pyrophosphokinase 1537862..1539031 Spirochaeta smaragdinae DSM 11293 9489528 YP_003803161.1 CDS Spirs_1440 NC_014364.1 1539043 1540452 D InterPro IPR001296; KEGG: dol:Dole_2515 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase 1539043..1540452 Spirochaeta smaragdinae DSM 11293 9489529 YP_003803162.1 CDS Spirs_1441 NC_014364.1 1540486 1541283 R COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: pho:PH0642 hypothetical protein; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: beta-ureidopropionase (beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase) (PydC); PFAM: carbon-nitrogen hydrolase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase complement(1540486..1541283) Spirochaeta smaragdinae DSM 11293 9489530 YP_003803163.1 CDS Spirs_1442 NC_014364.1 1541283 1542464 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dth:DICTH_0069 alcohol dehydrogenase II; PFAM: iron-containing alcohol dehydrogenase; SPTR: alcohol dehydrogenase II; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(1541283..1542464) Spirochaeta smaragdinae DSM 11293 9489531 YP_003803164.1 CDS Spirs_1443 NC_014364.1 1542851 1544434 R InterPro IPR006626; KEGG: abi:Aboo_0134 fibronectin type III domain protein; SPTR: uncharacterized protein; hypothetical protein complement(1542851..1544434) Spirochaeta smaragdinae DSM 11293 9489532 YP_003803165.1 CDS Spirs_1444 NC_014364.1 1544841 1546052 D COGs: COG0133 tryptophan synthase beta chain; InterPro IPR006653:IPR001926:IPR006654; KEGG: cps:CPS_1954 tryptophan synthase subunit beta; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: tryptophan synthase subunit beta; TIGRFAM: tryptophan synthase, beta subunit; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase subunit beta; tryptophan synthase subunit beta 1544841..1546052 Spirochaeta smaragdinae DSM 11293 9489533 YP_003803166.1 CDS Spirs_1445 NC_014364.1 1546058 1546819 R KEGG: afw:Anae109_1762 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1546058..1546819) Spirochaeta smaragdinae DSM 11293 9489534 YP_003803167.1 CDS Spirs_1446 NC_014364.1 1546841 1547896 R COGs: COG0082 chorismate synthase; InterPro IPR018522:IPR008162:IPR020541:IPR000453; KEGG: pjd:Pjdr2_2031 chorismate synthase; PFAM: chorismate synthase; PRIAM: chorismate synthase; SPTR: chorismate synthase; TIGRFAM: chorismate synthase; PFAM: chorismate synthase; TIGRFAM: chorismate synthase; chorismate synthase complement(1546841..1547896) Spirochaeta smaragdinae DSM 11293 9489535 YP_003803168.1 CDS Spirs_1447 NC_014364.1 1547900 1548490 R COGs: COG0703 shikimate kinase; InterPro IPR000623; KEGG: cte:CT1405 shikimate kinase; PFAM: shikimate kinase; SPTR: shikimate kinase; PFAM: shikimate kinase; shikimate kinase complement(1547900..1548490) Spirochaeta smaragdinae DSM 11293 9489536 YP_003803169.1 CDS Spirs_1448 NC_014364.1 1548538 1549938 D COGs: COG0114 Fumarase; InterPro IPR020557:IPR000362:IPR003031:IPR018951; KEGG: ddf:DEFDS_0234 fumarate hydratase class II; PFAM: fumarate lyase; Fumarase C-like; SPTR: fumarate hydratase, class II; PFAM: Fumarase C C-terminus; Lyase; fumarate lyase 1548538..1549938 Spirochaeta smaragdinae DSM 11293 9489537 YP_003803170.1 CDS Spirs_1449 NC_014364.1 1549935 1552019 R COGs: COG2200 FOG: EAL domain; InterProIPR001789:IPR013767:IPR000160:IPR001633:IPR 000014; KEGG: tgr:Tgr7_1990 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; response regulator receiver; PAS domain containing protein; SPTR: Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; response regulator receiver modulated PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase complement(1549935..1552019) Spirochaeta smaragdinae DSM 11293 9489538 YP_003803171.1 CDS Spirs_1450 NC_014364.1 1552140 1553390 D COGs: COG1362 aspartyl aminopeptidase; InterPro IPR001948; KEGG: psa:PST_1421 aminopeptidase 2; PFAM: peptidase M18 aminopeptidase I; SPTR: Probable M18 family aminopeptidase 2; PFAM: Aminopeptidase I zinc metalloprotease (M18); peptidase M18 aminopeptidase I 1552140..1553390 Spirochaeta smaragdinae DSM 11293 9489539 YP_003803172.1 CDS Spirs_1451 NC_014364.1 1553393 1554535 D COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR006674:IPR003607; KEGG: emi:Emin_0105 metal-dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: metal-dependent phosphohydrolase HD sub domain; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase; metal-dependent phosphohydrolase HD sub domain-containing protein 1553393..1554535 Spirochaeta smaragdinae DSM 11293 9489540 YP_003803173.1 CDS Spirs_1452 NC_014364.1 1554549 1555109 R COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: cbt:CLH_1643 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: Iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase complement(1554549..1555109) Spirochaeta smaragdinae DSM 11293 9489541 YP_003803174.1 CDS Spirs_1453 NC_014364.1 1555155 1555916 R COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR012840; KEGG: tde:TDE1856 radical SAM domain-containing protein; PFAM: radical SAM protein; SPTR: radical SAM domain protein; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein; anaerobic ribonucleoside-triphosphate reductase activating protein complement(1555155..1555916) Spirochaeta smaragdinae DSM 11293 9489542 YP_003803175.1 CDS Spirs_1454 NC_014364.1 1555920 1558403 R COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: tde:TDE1331 anaerobic ribonucleoside triphosphate reductase; PFAM: ATP-cone domain protein; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; anaerobic ribonucleoside-triphosphate reductase complement(1555920..1558403) Spirochaeta smaragdinae DSM 11293 9489543 YP_003803176.1 CDS Spirs_1455 NC_014364.1 1558384 1558869 R COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; InterPro IPR005144:IPR003796; KEGG: tde:TDE1330 transcriptional regulator NrdR; PFAM: ATP-cone domain protein; SPTR: transcriptional regulator NrdR; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR; ATP-cone domain-containing protein complement(1558384..1558869) Spirochaeta smaragdinae DSM 11293 9489544 YP_003803177.1 CDS Spirs_1456 NC_014364.1 1558998 1559717 D KEGG: hoh:Hoch_5250 protein of unknown function DUF1707; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2154); Domain of unknown function (DUF1707); hypothetical protein 1558998..1559717 Spirochaeta smaragdinae DSM 11293 9489545 YP_003803178.1 CDS Spirs_1457 NC_014364.1 1559752 1565586 D COGs: COG2373 Large extracellular alpha-helical protein; InterPro IPR002890:IPR011625:IPR001599; KEGG: scl:sce4409 hypothetical protein; PFAM: alpha-2-macroglobulin 2; alpha-2-macroglobulin domain protein; alpha-2-macroglobulin; SPTR: alpha-2-macroglobulin family N-region; PFAM: MG2 domain; alpha-2-macroglobulin family; alpha-2-macroglobulin MG1 domain; alpha-2-macroglobulin family N-terminal region; alpha-2-macroglobulin 2 1559752..1565586 Spirochaeta smaragdinae DSM 11293 9489546 YP_003803179.1 CDS Spirs_1458 NC_014364.1 1565573 1567870 D COGs: COG4953 membrane carboxypeptidase/penicillin-binding protein PbpC; InterPro IPR001264:IPR001460; KEGG: npu:Npun_R3281 penicillin-binding protein 1C; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1C; manually curated; PFAM: Penicillin binding protein transpeptidase domain; transglycosylase; TIGRFAM: penicillin-binding protein 1C; peptidoglycan glycosyltransferase 1565573..1567870 Spirochaeta smaragdinae DSM 11293 9489547 YP_003803180.1 CDS Spirs_1459 NC_014364.1 1567871 1568815 R COGs: COG0863 DNA modification methylase; InterPro IPR002052:IPR001091:IPR002941; KEGG: efa:EF1452 adenine methyltransferase, PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6; PFAM: DNA methylase; DNA methylase N-4/N-6 domain-containing protein complement(1567871..1568815) Spirochaeta smaragdinae DSM 11293 9489548 YP_003803181.1 CDS Spirs_1460 NC_014364.1 1568836 1570098 R COGs: COG0019 diaminopimelate decarboxylase; InterPro IPR000183:IPR002986; KEGG: mma:MM_1885 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: diaminopimelate decarboxylase; PFAM: pyridoxal-dependent decarboxylase, C-terminal sheet domain; pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase; Orn/DAP/Arg decarboxylase 2 complement(1568836..1570098) Spirochaeta smaragdinae DSM 11293 9489549 YP_003803182.1 CDS Spirs_1461 NC_014364.1 1570134 1571363 R COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR019942; KEGG: gsu:GSU0162 L,L-diaminopimelate aminotransferase; PFAM: aminotransferase class I and II; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase; LL-diaminopimelate aminotransferase complement(1570134..1571363) Spirochaeta smaragdinae DSM 11293 9489550 YP_003803183.1 CDS Spirs_1462 NC_014364.1 1571392 1572297 R COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR020624:IPR002220:IPR005263; KEGG: kse:Ksed_00780 dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthase; TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase; dihydrodipicolinate synthase complement(1571392..1572297) Spirochaeta smaragdinae DSM 11293 9489551 YP_003803184.1 CDS Spirs_1463 NC_014364.1 1572415 1573074 D KEGG: rbi:RB2501_05130 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1572415..1573074 Spirochaeta smaragdinae DSM 11293 9489552 YP_003803185.1 CDS Spirs_1464 NC_014364.1 1573071 1573607 D KEGG: ape:APE_0781.1 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF265; hypothetical protein 1573071..1573607 Spirochaeta smaragdinae DSM 11293 9489553 YP_003803186.1 CDS Spirs_1465 NC_014364.1 1573633 1573866 R KEGG: vha:VIBHAR_03415 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1573633..1573866) Spirochaeta smaragdinae DSM 11293 9489554 YP_003803187.1 CDS Spirs_1466 NC_014364.1 1573995 1574576 D KEGG: tdn:Suden_0394 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1573995..1574576 Spirochaeta smaragdinae DSM 11293 9489555 YP_003803188.1 CDS Spirs_1467 NC_014364.1 1574647 1575951 D COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR018044:IPR001967; KEGG: sth:STH2587 D-alanyl-D-alanine carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; SPTR: D-alanyl-D-alanine carboxypeptidase; PFAM: D-alanyl-D-alanine carboxypeptidase; peptidase S11 D-alanyl-D-alanine carboxypeptidase 1 1574647..1575951 Spirochaeta smaragdinae DSM 11293 9489556 YP_003803189.1 CDS Spirs_1468 NC_014364.1 1575977 1576309 R COGs: COG4802 Ferredoxin-thioredoxin reductase catalytic subunit; KEGG: dol:Dole_2967 hypothetical protein; SPTR: uncharacterized protein; PFAM: Ferredoxin thioredoxin reductase catalytic beta chain; hypothetical protein complement(1575977..1576309) Spirochaeta smaragdinae DSM 11293 9489557 YP_003803190.1 CDS Spirs_1469 NC_014364.1 1576312 1576611 R InterPro IPR002109; KEGG: mth:MTH1577 hypothetical protein; PFAM: glutaredoxin; SPTR: uncharacterized protein; PFAM: glutaredoxin; glutaredoxin complement(1576312..1576611) Spirochaeta smaragdinae DSM 11293 9489558 YP_003803191.1 CDS Spirs_1470 NC_014364.1 1576679 1577155 R KEGG: pfh:PFHG_01551 conserved hypothetical protein; SPTR: chromosome 17 SCAF15006, whole genome shotgun sequence.; hypothetical protein complement(1576679..1577155) Spirochaeta smaragdinae DSM 11293 9489559 YP_003803192.1 CDS Spirs_1471 NC_014364.1 1577152 1578168 R COGs: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenase; InterPro IPR000262:IPR012133:IPR017934; KEGG: dvl:Dvul_0528 FMN-dependent alpha-hydroxy acid dehydrogenase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; SPTR: dehydrogenase, FMN-dependent family; PFAM: FMN-dependent dehydrogenase; FMN-dependent alpha-hydroxy acid dehydrogenase complement(1577152..1578168) Spirochaeta smaragdinae DSM 11293 9489560 YP_003803193.1 CDS Spirs_1472 NC_014364.1 1578171 1579052 R InterPro IPR017937:IPR000866:IPR017936; KEGG: alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: Cof-like hydrolase; PFAM: AhpC/TSA family; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen complement(1578171..1579052) Spirochaeta smaragdinae DSM 11293 9489561 YP_003803194.1 CDS Spirs_1473 NC_014364.1 1579074 1579442 R COGs: COG1433 conserved hypothetical protein; InterPro IPR003731; KEGG: dsa:Desal_0066 dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: dinitrogenase iron-molybdenum cofactor biosynthesis protein; SPTR: dinitrogenase iron-molybdenum cofactor biosynthesis protein; PFAM: dinitrogenase iron-molybdenum cofactor; dinitrogenase iron-molybdenum cofactor biosynthesis protein complement(1579074..1579442) Spirochaeta smaragdinae DSM 11293 9489562 YP_003803195.1 CDS Spirs_1474 NC_014364.1 1579503 1579748 R InterPro IPR006121; KEGG: tte:TTE2463 cation transport ATPase; PFAM: Heavy metal transport/detoxification protein; SPTR: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: Heavy-metal-associated domain; Heavy metal transport/detoxification protein complement(1579503..1579748) Spirochaeta smaragdinae DSM 11293 9489563 YP_003803196.1 CDS Spirs_1475 NC_014364.1 1579795 1580256 R COGs: COG3467 flavin-nucleotide-binding protein; KEGG: dap:Dacet_0115 pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; SPTR: pyridoxamine 5'-phosphate oxidase-related FMN-binding protein; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein complement(1579795..1580256) Spirochaeta smaragdinae DSM 11293 9489564 YP_003803197.1 CDS Spirs_1476 NC_014364.1 1580278 1581612 R COGs: COG1109 phosphomannomutase; InterProIPR016066:IPR005841:IPR005844:IPR005845:IPR 005846:IPR005843; KEGG: sti:Sthe_1355 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I complement(1580278..1581612) Spirochaeta smaragdinae DSM 11293 9489565 YP_003803198.1 CDS Spirs_1477 NC_014364.1 1581609 1582067 R KEGG: cpv:cgd6_5110 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1581609..1582067) Spirochaeta smaragdinae DSM 11293 9489566 YP_003803199.1 CDS Spirs_1478 NC_014364.1 1582114 1582533 R COGs: COG1765 redox protein regulator of disulfide bond formation; InterPro IPR003718; KEGG: sth:STH27 hypothetical protein; PFAM: OsmC family protein; SPTR: uncharacterized protein; PFAM: OsmC-like protein; OsmC family protein complement(1582114..1582533) Spirochaeta smaragdinae DSM 11293 9489567 YP_003803200.1 CDS Spirs_1479 NC_014364.1 1582616 1583617 D COGs: COG1092 SAM-dependent methyltransferase; KEGG: pca:Pcar_2072 23S rRNA m(2)G2445 methyltransferase; PRIAM: rRNA (guanine-N(2)-)-methyltransferase; SPTR: uncharacterized protein; PFAM: S-adenosylmethionine-dependent methyltransferase; rRNA (guanine-N(2)-)-methyltransferase 1582616..1583617 Spirochaeta smaragdinae DSM 11293 9489568 YP_003803201.1 CDS Spirs_1480 NC_014364.1 1583565 1584881 R InterPro IPR006992; KEGG: cte:CT1115 hypothetical protein; PFAM: amidohydrolase 2; SPTR: uncharacterized protein; PFAM: Amidohydrolase; amidohydrolase 2 complement(1583565..1584881) Spirochaeta smaragdinae DSM 11293 9489569 YP_003803202.1 CDS Spirs_1481 NC_014364.1 1584887 1586569 R COGs: COG0008 glutamyl- and glutaminyl-tRNA synthetase; InterProIPR001412:IPR020060:IPR020058:IPR020059:IPR 004514; KEGG: cth:Cthe_0917 glutaminyl-tRNA synthetase; PFAM: glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; SPTR: glutaminyl-tRNA synthetase; TIGRFAM: glutaminyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase; glutaminyl-tRNA synthetase complement(1584887..1586569) Spirochaeta smaragdinae DSM 11293 9489570 YP_003803203.1 CDS Spirs_1482 NC_014364.1 1586647 1587765 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dev:DhcVS_1162 GGDEF domain protein; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: GGDEF domain protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(1586647..1587765) Spirochaeta smaragdinae DSM 11293 9489571 YP_003803204.1 CDS Spirs_1483 NC_014364.1 1587789 1589402 R COGs: COG4172 ABC-type uncharacterized transporter duplicated ATPase component; InterPro IPR017871:IPR003439:IPR013563:IPR003593; KEGG: pae:PA1807 ABC transporter ATP-binding protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: Probable ATP-binding component of ABC transporter; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: phosphonate C-P lyase system protein PhnK; ABC transporter complement(1587789..1589402) Spirochaeta smaragdinae DSM 11293 9489572 YP_003803205.1 CDS Spirs_1484 NC_014364.1 1589399 1590418 R COGs: COG4239 ABC-type uncharacterized transporter permease; InterPro IPR000515; KEGG: maq:Maqu_1540 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1589399..1590418) Spirochaeta smaragdinae DSM 11293 9489573 YP_003803206.1 CDS Spirs_1485 NC_014364.1 1590418 1591518 R COGs: COG4174 ABC-type uncharacterized transporter permease; InterPro IPR000515; KEGG: ddc:Dd586_2373 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1590418..1591518) Spirochaeta smaragdinae DSM 11293 9489574 YP_003803207.1 CDS Spirs_1486 NC_014364.1 1591522 1593327 R COGs: COG4166 ABC-type oligopeptide transporter periplasmic component; InterPro IPR000914; KEGG: hch:HCH_02522 ABC-type oligopeptide transporter, periplasmic component; PFAM: extracellular solute-binding protein family 5; SPTR: ABC-type oligopeptide transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein complement(1591522..1593327) Spirochaeta smaragdinae DSM 11293 9489575 YP_003803208.1 CDS Spirs_1487 NC_014364.1 1593507 1595138 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR003018:IPR011495:IPR003594:IPR000014:IPR 005467; KEGG: bph:Bphy_4528 histidine kinase dimerisation/phosphoacceptor; PFAM: histidine kinase dimerisation/phosphoacceptor; GAF domain protein; ATP-binding region ATPase domain protein; SMART: GAF domain protein; ATP-binding region ATPase domain protein; SPTR: histidine kinase dimerisation/phosphoacceptor; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 1593507..1595138 Spirochaeta smaragdinae DSM 11293 9489576 YP_003803209.1 CDS Spirs_1488 NC_014364.1 1595181 1596059 D InterPro IPR000620; KEGG: dat:HRM2_13600 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family; hypothetical protein 1595181..1596059 Spirochaeta smaragdinae DSM 11293 9489577 YP_003803210.1 CDS Spirs_1489 NC_014364.1 1596056 1596925 D InterPro IPR000620; KEGG: cno:NT01CX_0638 transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: transporter; PFAM: EamA-like transporter family; hypothetical protein 1596056..1596925 Spirochaeta smaragdinae DSM 11293 9489578 YP_003803211.1 CDS Spirs_1490 NC_014364.1 1596903 1597679 R COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013; KEGG: cpe:CPE0972 histidinol phosphatase; PFAM: PHP domain protein; SPTR: Probable histidinol phosphatase; manually curated; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family; PHP domain-containing protein complement(1596903..1597679) Spirochaeta smaragdinae DSM 11293 9489579 YP_003803212.1 CDS Spirs_1491 NC_014364.1 1597769 1598071 D InterPro IPR000831:IPR013335; KEGG: emi:Emin_0550 Trp repressor; PFAM: Trp repressor; SPTR: Trp repressor; PFAM: Trp repressor protein; TIGRFAM: trp operon repressor, proteobacterial; Trp repressor 1597769..1598071 Spirochaeta smaragdinae DSM 11293 9489580 YP_003803213.1 CDS Spirs_1492 NC_014364.1 1598043 1598852 R COGs: COG1647 esterase/lipase; InterPro IPR012354; KEGG: pmo:Pmob_0119 carboxylesterase, SPTR: carboxylesterase, ; manually curated; carboxylesterase complement(1598043..1598852) Spirochaeta smaragdinae DSM 11293 9489581 YP_003803214.1 CDS Spirs_1493 NC_014364.1 1598969 1599859 D InterPro IPR002110:IPR020683; KEGG: tde:TDE2450 ankyrin repeateat-containing protein; SMART: ankyrin; SPTR: ankyrin repeat protein; PFAM: ankyrin repeat; ankyrin 1598969..1599859 Spirochaeta smaragdinae DSM 11293 9489582 YP_003803215.1 CDS Spirs_1494 NC_014364.1 1599849 1600382 D KEGG: bfs:BF1895 LPS biosynthesis related membrane protein; SPTR: uncharacterized protein; hypothetical protein 1599849..1600382 Spirochaeta smaragdinae DSM 11293 9489583 YP_003803216.1 CDS Spirs_1495 NC_014364.1 1600423 1601148 D KEGG: ame:410558 similar to CG4557-PA; SPTR: uncharacterized protein; hypothetical protein 1600423..1601148 Spirochaeta smaragdinae DSM 11293 9489584 YP_003803217.1 CDS Spirs_1496 NC_014364.1 1601149 1602393 R InterPro IPR005362:IPR013105:IPR019734:IPR013026; KEGG: tde:TDE2117 hypothetical protein; PFAM: protein of unknown function UPF0164; hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0164); Tetratricopeptide repeat; hypothetical protein complement(1601149..1602393) Spirochaeta smaragdinae DSM 11293 9489585 YP_003803218.1 CDS Spirs_1497 NC_014364.1 1602484 1605477 D InterPro IPR006061; KEGG: tde:TDE2116 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; hypothetical protein 1602484..1605477 Spirochaeta smaragdinae DSM 11293 9489586 YP_003803219.1 CDS Spirs_1498 NC_014364.1 1605477 1610150 D COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterProIPR018181:IPR003660:IPR010822:IPR001932:IPR 003961; KEGG: tde:TDE2115 HAMP domain-containing protein; PFAM: stage II sporulation E family protein; histidine kinase HAMP region domain protein; SMART: protein phosphatase 2C domain protein; histidine kinase HAMP region domain protein; SPTR: HAMP domain protein; PFAM: HAMP domain; stage II sporulation protein E (SpoIIE); protein serine/threonine phosphatase 1605477..1610150 Spirochaeta smaragdinae DSM 11293 9489587 YP_003803220.1 CDS Spirs_1499 NC_014364.1 1610155 1610475 D KEGG: tde:TDE2660 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1610155..1610475 Spirochaeta smaragdinae DSM 11293 9489588 YP_003803221.1 CDS Spirs_1500 NC_014364.1 1610463 1611236 R COGs: COG1489 DNA-binding protein stimulates sugar fermentation; InterPro IPR005224; KEGG: str:Sterm_2325 sugar fermentation stimulation protein; PFAM: sugar fermentation stimulation protein; SPTR: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; PFAM: Sugar fermentation stimulation protein; TIGRFAM: sugar fermentation stimulation protein; sugar fermentation stimulation protein complement(1610463..1611236) Spirochaeta smaragdinae DSM 11293 9489589 YP_003803222.1 CDS Spirs_1501 NC_014364.1 1611211 1613115 R COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR020459:IPR000873; KEGG: bbu:BB0593 long-chain-fatty-acid CoA ligase; PFAM: AMP-dependent synthetase and ligase; SPTR: Long-chain-fatty-acid CoA ligase; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase complement(1611211..1613115) Spirochaeta smaragdinae DSM 11293 9489590 YP_003803223.1 CDS Spirs_1502 NC_014364.1 1613152 1614936 R COGs: COG4232 thiol:disulfide interchange protein; InterPro IPR001986:IPR003834; KEGG: cts:Ctha_0233 cytochrome C biogenesis protein transmembrane region; PFAM: cytochrome C biogenesis protein transmembrane region; PRIAM: protein-disulfide reductase; SPTR: thiol:disulfide interchange protein dsbD (DsbD-like) (protein-disulfide reductase) (disulfide reductase); membrane protein; PFAM: disulfide bond corrector protein DsbC; cytochrome C biogenesis protein transmembrane region; protein-disulfide reductase complement(1613152..1614936) Spirochaeta smaragdinae DSM 11293 9489591 YP_003803224.1 CDS Spirs_1503 NC_014364.1 1614952 1615506 R COGs: COG0526 thiol-disulfide isomerase and thioredoxins; InterPro IPR017937:IPR000866:IPR017936; KEGG: gbm:Gbem_3412 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; SPTR: Alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen; PFAM: AhpC/TSA family; alkyl hydroperoxide reductase/ thiol specific antioxidant/ Mal allergen complement(1614952..1615506) Spirochaeta smaragdinae DSM 11293 9489592 YP_003803225.1 CDS Spirs_1504 NC_014364.1 1615586 1616284 R InterPro IPR003675; KEGG: bga:BG0605 hypothetical protein; PFAM: hypothetical protein; SPTR: CAAX amino protease family protein; PFAM: CAAX amino terminal protease family; hypothetical protein complement(1615586..1616284) Spirochaeta smaragdinae DSM 11293 9489593 YP_003803226.1 CDS Spirs_1505 NC_014364.1 1616354 1617406 D InterPro IPR009875; KEGG: tde:TDE1318 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; PFAM: PilZ domain; type IV pilus assembly PilZ 1616354..1617406 Spirochaeta smaragdinae DSM 11293 9489594 YP_003803227.1 CDS Spirs_1506 NC_014364.1 1617421 1618638 D KEGG: tde:TDE1319 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1617421..1618638 Spirochaeta smaragdinae DSM 11293 9489595 YP_003803228.1 CDS Spirs_1507 NC_014364.1 1618901 1620220 D InterPro IPR004477; KEGG: bth:BT_3947 competence protein; PFAM: ComEC/Rec2-related protein; SPTR: ComEC/Rec2-related protein; TIGRFAM: ComEC/Rec2-related protein; PFAM: Competence protein; TIGRFAM: ComEC/Rec2-related protein; ComEC/Rec2-like protein 1618901..1620220 Spirochaeta smaragdinae DSM 11293 9489596 YP_003803229.1 CDS Spirs_1508 NC_014364.1 1620078 1620959 D COGs: COG0030 dimethyladenosine transferase (rRNA methylation); InterPro IPR020596:IPR001737:IPR011530:IPR020598; KEGG: tde:TDE1080 dimethyladenosine transferase; PFAM: ribosomal RNA adenine methylase transferase; SMART: ribosomal RNA adenine methylase transferase-like; SPTR: dimethyladenosine transferase; TIGRFAM: dimethyladenosine transferase; manually curated; PFAM: ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase; dimethyladenosine transferase 1620078..1620959 Spirochaeta smaragdinae DSM 11293 9489597 YP_003803230.1 CDS Spirs_1509 NC_014364.1 1621001 1621882 D KEGG: coc:Coch_0328 hypothetical protein; SPTR: YD repeat protein; hypothetical protein 1621001..1621882 Spirochaeta smaragdinae DSM 11293 9489598 YP_003803231.1 CDS Spirs_1510 NC_014364.1 1621890 1623092 D InterPro IPR004155; KEGG: csa:Csal_0697 chromosome segregation protein SMC; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: chromosome segregation protein SMC; PBS lyase HEAT domain-containing protein repeat-containing protein 1621890..1623092 Spirochaeta smaragdinae DSM 11293 9489599 YP_003803232.1 CDS Spirs_1511 NC_014364.1 1623272 1623859 R InterPro IPR001647; KEGG: dal:Dalk_0754 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: YsiA-like protein, C-terminal region; Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(1623272..1623859) Spirochaeta smaragdinae DSM 11293 9489600 YP_003803233.1 CDS Spirs_1512 NC_014364.1 1624024 1625019 R COGs: COG0280 phosphotransacetylase; InterPro IPR002505:IPR004614:IPR012147; KEGG: hor:Hore_10200 phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: phosphate acetyltransferase; SPTR: phosphate acetyltransferase; TIGRFAM: phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; TIGRFAM: phosphate acetyltransferase; phosphate acetyltransferase complement(1624024..1625019) Spirochaeta smaragdinae DSM 11293 9489601 YP_003803234.1 CDS Spirs_1513 NC_014364.1 1625164 1625919 D COGs: COG0287 prephenate dehydrogenase; InterPro IPR003099; KEGG: cbc:CbuK_0855 prephenate dehydrogenase; PFAM: prephenate dehydrogenase; SPTR: prephenate dehydrogenase; PFAM: prephenate dehydrogenase; prephenate dehydrogenase 1625164..1625919 Spirochaeta smaragdinae DSM 11293 9489602 YP_003803235.1 CDS Spirs_1514 NC_014364.1 1625973 1626350 D COGs: COG1664 integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: tde:TDE1888 hypothetical protein; PFAM: protein of unknown function DUF583; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF583; hypothetical protein 1625973..1626350 Spirochaeta smaragdinae DSM 11293 9489603 YP_003803236.1 CDS Spirs_1515 NC_014364.1 1626358 1626996 D InterPro IPR001440:IPR019734:IPR013026; KEGG: tde:TDE1887 hypothetical protein; PFAM: hypothetical protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein 1626358..1626996 Spirochaeta smaragdinae DSM 11293 9489604 YP_003803237.1 CDS Spirs_1516 NC_014364.1 1626996 1628357 D COGs: COG0621 2-methylthioadenine synthetase; InterProIPR013848:IPR007197:IPR005839:IPR006467:IPR 006638; KEGG: tde:TDE1886 MiaB-like tRNA modifying enzyme; PFAM: radical SAM protein; protein of unknown function UPF0004; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; PFAM: radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; RNA modification enzyme, MiaB family; MiaB-like tRNA modifying protein 1626996..1628357 Spirochaeta smaragdinae DSM 11293 9489605 YP_003803238.1 CDS Spirs_1517 NC_014364.1 1628489 1629274 D KEGG: sde:Sde_1294 polyhydroxyalkanoate synthesis repressor PhaR; SPTR: VCBS domain protein; hypothetical protein 1628489..1629274 Spirochaeta smaragdinae DSM 11293 9489606 YP_003803239.1 CDS Spirs_1518 NC_014364.1 1629288 1630433 D KEGG: pmx:PERMA_0993 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1629288..1630433 Spirochaeta smaragdinae DSM 11293 9489607 YP_003803240.1 CDS Spirs_1519 NC_014364.1 1630455 1631111 D KEGG: nph:NP1756A transducer protein htr22; SPTR: uncharacterized protein; hypothetical protein 1630455..1631111 Spirochaeta smaragdinae DSM 11293 9489608 YP_003803241.1 CDS Spirs_1520 NC_014364.1 1631130 1632281 D KEGG: tde:TDE1884 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1631130..1632281 Spirochaeta smaragdinae DSM 11293 9489609 YP_003803242.1 CDS Spirs_1521 NC_014364.1 1632843 1633499 D COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: cdl:CDR20291_1993 iron-sulfur flavoprotein; PFAM: NADPH-dependent FMN reductase; SPTR: uncharacterized protein; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 1632843..1633499 Spirochaeta smaragdinae DSM 11293 9489612 YP_003803243.1 CDS Spirs_1522 NC_014364.1 1633537 1634523 D COGs: COG2358 TRAP-type uncharacterized transporter periplasmic component; InterPro IPR011852; KEGG: amt:Amet_4703 TRAP transporter solute receptor TAXI family protein; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 1633537..1634523 Spirochaeta smaragdinae DSM 11293 9489613 YP_003803244.1 CDS Spirs_1523 NC_014364.1 1634586 1636502 D COGs: COG4666 TRAP-type uncharacterized transporter fused permeases; InterPro IPR010656:IPR011853; KEGG: drm:Dred_3211 TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP transporter 4TM/12TM fusion protein; TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter 4TM/12TM fusion protein; TRAP transporter 4TM/12TM fusion protein 1634586..1636502 Spirochaeta smaragdinae DSM 11293 9489614 YP_003803245.1 CDS Spirs_1524 NC_014364.1 1636499 1636768 D KEGG: met:M446_0096 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1636499..1636768 Spirochaeta smaragdinae DSM 11293 9489615 YP_003803246.1 CDS Spirs_1525 NC_014364.1 1636835 1637728 R COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: ttu:TERTU_3489 hypothetical protein; PFAM: CheW domain protein; SPTR: uncharacterized protein; PFAM: CheW-like domain; chemotaxis protein CheW complement(1636835..1637728) Spirochaeta smaragdinae DSM 11293 9489616 YP_003803247.1 CDS Spirs_1526 NC_014364.1 1637788 1638252 R KEGG: dth:DICTH_0124 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1637788..1638252) Spirochaeta smaragdinae DSM 11293 9489617 YP_003803248.1 CDS Spirs_1527 NC_014364.1 1638406 1639467 D COGs: COG0035 uracil phosphoribosyltransferase; KEGG: tde:TDE1612 phosphoribosyl transferase domain-containing protein; SPTR: phosphoribosyl transferase domain protein; phosphoribosyl transferase domain-containing protein 1638406..1639467 Spirochaeta smaragdinae DSM 11293 9489618 YP_003803249.1 CDS Spirs_1528 NC_014364.1 1639475 1640467 D InterPro IPR001440:IPR019734:IPR013026; KEGG: pgn:PGN_0996 TPR domain protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: TPR-containing nuclear phosphoprotein that regulates K(+) uptake (ISS); hypothetical protein 1639475..1640467 Spirochaeta smaragdinae DSM 11293 9489619 YP_003803250.1 CDS Spirs_1529 NC_014364.1 1640473 1641108 R COGs: COG0563 adenylate kinase and related kinase; InterPro IPR000850:IPR007862:IPR006259; KEGG: tde:TDE1112 adenylate kinase; PFAM: adenylate kinase; adenylate kinase lid domain protein; SPTR: adenylate kinase; TIGRFAM: adenylate kinase; PFAM: adenylate kinase, active site lid; adenylate kinase; TIGRFAM: adenylate kinases; adenylate kinase complement(1640473..1641108) Spirochaeta smaragdinae DSM 11293 9489620 YP_003803251.1 CDS Spirs_1530 NC_014364.1 1641408 1641761 D KEGG: ape:APE_1216 surface layer protein; SPTR: M protein; hypothetical protein 1641408..1641761 Spirochaeta smaragdinae DSM 11293 9489621 YP_003803252.1 CDS Spirs_1531 NC_014364.1 1647185 1648045 D InterPro IPR006015:IPR006016; KEGG: pmx:PERMA_1283 universal stress protein family protein; PFAM: UspA domain protein; SPTR: Universal stress protein family protein; PFAM: Universal stress protein family; UspA domain-containing protein 1647185..1648045 Spirochaeta smaragdinae DSM 11293 9489626 YP_003803253.1 CDS Spirs_1532 NC_014364.1 1648122 1648604 D COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: tde:TDE1589 purine-binding chemotaxis protein; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Purine-binding chemotaxis protein; PFAM: CheW-like domain; chemotaxis protein CheW 1648122..1648604 Spirochaeta smaragdinae DSM 11293 9489627 YP_003803254.1 CDS Spirs_1533 NC_014364.1 1648621 1649634 D COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tde:TDE1590 aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Aminotransferase, DegT/DnrJ/EryC1/StrS family; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; DegT/DnrJ/EryC1/StrS aminotransferase 1648621..1649634 Spirochaeta smaragdinae DSM 11293 9489628 YP_003803255.1 CDS Spirs_1534 NC_014364.1 1649642 1650496 D COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: tde:TDE1591 inorganic polyphosphate/ATP-NAD kinase, PFAM: ATP-NAD/AcoX kinase; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase; PFAM: ATP-NAD kinase; ATP-NAD/AcoX kinase 1649642..1650496 Spirochaeta smaragdinae DSM 11293 9489629 YP_003803256.1 CDS Spirs_1535 NC_014364.1 1650489 1652177 D COGs: COG0497 ATPase involved in DNA repair; InterPro IPR004604:IPR003395:IPR003593; KEGG: tde:TDE1301 DNA repair protein RecN; PFAM: SMC domain protein; SMART: ATPase AAA; SPTR: DNA repair protein RecN; TIGRFAM: DNA repair protein RecN; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN; DNA repair protein RecN 1650489..1652177 Spirochaeta smaragdinae DSM 11293 9489630 YP_003803257.1 CDS Spirs_1536 NC_014364.1 1652199 1653014 D KEGG: tde:TDE1300 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1652199..1653014 Spirochaeta smaragdinae DSM 11293 9489631 YP_003803258.1 CDS Spirs_1537 NC_014364.1 1653011 1654048 D KEGG: tpp:TPASS_0783 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1653011..1654048 Spirochaeta smaragdinae DSM 11293 9489632 YP_003803259.1 CDS Spirs_1538 NC_014364.1 1654052 1654921 D InterPro IPR016047; KEGG: tde:TDE1929 hypothetical protein; PFAM: peptidase M23; SPTR: uncharacterized protein; PFAM: peptidase family M23; peptidase M23 1654052..1654921 Spirochaeta smaragdinae DSM 11293 9489633 YP_003803260.1 CDS Spirs_1539 NC_014364.1 1654925 1655773 D InterPro IPR013216; KEGG: bhy:BHWA1_00413 methyltransferase; PFAM: methyltransferase type 11; SPTR: methyltransferase; PFAM: methyltransferase domain; type 11 methyltransferase 1654925..1655773 Spirochaeta smaragdinae DSM 11293 9489634 YP_003803261.1 CDS Spirs_1540 NC_014364.1 1655802 1658216 R COGs: COG1449 alpha-amylase/alpha-mannosidase; InterPro IPR004300; KEGG: fsu:Fisuc_0731 glycoside hydrolase family 57; PFAM: glycoside hydrolase family 57; SPTR: glycoside hydrolase family 57; PFAM: glycosyl hydrolase family 57; Domain of unknown function (DUF3536); glycoside hydrolase family protein complement(1655802..1658216) Spirochaeta smaragdinae DSM 11293 9489635 YP_003803262.1 CDS Spirs_1541 NC_014364.1 1658326 1659081 D COGs: COG3330 conserved hypothetical protein; KEGG: tde:TDE1093 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1658326..1659081 Spirochaeta smaragdinae DSM 11293 9489636 YP_003803263.1 CDS Spirs_1542 NC_014364.1 1659100 1660683 D COGs: COG1543 conserved hypothetical protein; InterPro IPR004300:IPR015293; KEGG: pth:PTH_2228 hypothetical protein; PFAM: Domain of unknown function DUF1957; glycoside hydrolase family 57; SPTR: Uncharacterized conserved protein; PFAM: Domain of unknown function (DUF1957); glycosyl hydrolase family 57; hypothetical protein 1659100..1660683 Spirochaeta smaragdinae DSM 11293 9489637 YP_003803264.1 CDS Spirs_1543 NC_014364.1 1660693 1660941 R KEGG: tpp:TPASS_0666 hypothetical protein; SPTR: uncharacterized protein; manually curated; hypothetical protein complement(1660693..1660941) Spirochaeta smaragdinae DSM 11293 9489638 YP_003803265.1 CDS Spirs_1544 NC_014364.1 1661125 1661580 D COGs: COG2001 conserved hypothetical protein; InterPro IPR003444:IPR020603:IPR019775; KEGG: tde:TDE1197 cell division protein MraZ; PFAM: MraZ domain; SPTR: protein mraZ; TIGRFAM: MraZ protein; PFAM: MraZ protein; TIGRFAM: mraZ protein; MraZ protein 1661125..1661580 Spirochaeta smaragdinae DSM 11293 9489639 YP_003803266.1 CDS Spirs_1545 NC_014364.1 1661589 1662551 D COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: tde:TDE1198 S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; SPTR: S-adenosyl-L-methionine-dependent methyltransferase mraW; TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW; S-adenosyl-methyltransferase MraW 1661589..1662551 Spirochaeta smaragdinae DSM 11293 9489640 YP_003803267.1 CDS Spirs_1546 NC_014364.1 1662552 1662845 D KEGG: tde:TDE1199 cell division protein FtsL, SPTR: cell division protein FtsL; PFAM: cell division protein FtsL; TIGRFAM: cell division protein FtsL; cell division protein FtsL 1662552..1662845 Spirochaeta smaragdinae DSM 11293 9489641 YP_003803268.1 CDS Spirs_1547 NC_014364.1 1662838 1664274 D COGs: COG0770 UDP-N-acetylmuramyl pentapeptide synthase; InterPro IPR005863:IPR000713:IPR013221:IPR004101; KEGG: tpp:TPASS_0386 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate- -D-alanyl- D-alanine; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-d iaminopimelate/D-alanyl-D-alanylligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanylligase 1662838..1664274 Spirochaeta smaragdinae DSM 11293 9489642 YP_003803269.1 CDS Spirs_1548 NC_014364.1 1664267 1665346 D COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR003524:IPR018480:IPR018481; KEGG: gme:Gmet_0409 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: glycosyl transferase, family 4, conserved region; phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM:phospho-N-acetylmuramoyl-pentapeptide-trans ferase; PFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase; phospho-N-acetylmuramoyl-pentapeptide- transferase 1664267..1665346 Spirochaeta smaragdinae DSM 11293 9489643 YP_003803270.1 CDS Spirs_1549 NC_014364.1 1665356 1666501 D COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437:IPR001182; KEGG: tde:TDE1201 cell cycle protein FtsW; PFAM: cell cycle protein; SPTR: cell cycle protein, FtsW/RodA/SpoVE family; TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; TIGRFAM: cell division protein FtsW; cell division protein FtsW 1665356..1666501 Spirochaeta smaragdinae DSM 11293 9489644 YP_003803271.1 CDS Spirs_1550 NC_014364.1 1666498 1667316 D COGs: COG1589 cell division septal protein; InterPro IPR013685; KEGG: tde:TDE1202 cell division protein FtsQ, PFAM: polypeptide-transport-associated domain protein FtsQ-type; SPTR: cell division protein FtsQ, ; PFAM: POTRA domain, FtsQ-type; polypeptide-transport-associated domain-containing protein FtsQ-type 1666498..1667316 Spirochaeta smaragdinae DSM 11293 9489645 YP_003803272.1 CDS Spirs_1551 NC_014364.1 1667318 1668553 D COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR020823:IPR003494; KEGG: mxa:MXAN_5599 cell division protein FtsA; PFAM: cell division protein FtsA; SPTR: cell division protein FtsA; TIGRFAM: cell division protein FtsA; PFAM: cell division protein FtsA; TIGRFAM: cell division protein FtsA; cell division protein FtsA 1667318..1668553 Spirochaeta smaragdinae DSM 11293 9489646 YP_003803273.1 CDS Spirs_1552 NC_014364.1 1668648 1669826 D COGs: COG0206 cell division GTPase; InterPro IPR000158:IPR003008:IPR018316:IPR020805; KEGG: bre:BRE_306 cell division protein FtsZ; PFAM: Tubulin/FtsZ GTPase; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: cell division protein ftsZ; TIGRFAM: cell division protein FtsZ; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ; cell division protein FtsZ 1668648..1669826 Spirochaeta smaragdinae DSM 11293 9489647 YP_003803274.1 CDS Spirs_1553 NC_014364.1 1669839 1670774 D COGs: COG4974 Site-specific recombinase XerD; InterPro IPR011932:IPR004107:IPR002104; KEGG: tde:TDE1205 integrase/recombinase XerD; PFAM: integrase family protein; integrase domain protein SAM domain protein; SPTR: Integrase/recombinase XerD; TIGRFAM: tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; TIGRFAM: tyrosine recombinase XerD; tyrosine recombinase XerD 1669839..1670774 Spirochaeta smaragdinae DSM 11293 9489648 YP_003803275.1 CDS Spirs_1554 NC_014364.1 1670791 1671516 D KEGG: tde:TDE1206 hypothetical protein; SPTR: TPR domain protein; hypothetical protein 1670791..1671516 Spirochaeta smaragdinae DSM 11293 9489649 YP_003803276.1 CDS Spirs_1555 NC_014364.1 1671509 1672522 D COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: pca:Pcar_0408 Rossmann-fold nucleotide-binding protein; PFAM: SMF family protein; SPTR: Smf protein; TIGRFAM: DNA protecting protein DprA; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA; DNA protecting protein DprA 1671509..1672522 Spirochaeta smaragdinae DSM 11293 9489650 YP_003803277.1 CDS Spirs_1556 NC_014364.1 1672515 1673456 D COGs: COG4974 Site-specific recombinase XerD; InterPro IPR004107:IPR002104; KEGG: dau:Daud_0602 phage integrase family protein; PFAM: integrase family protein; integrase; SPTR: Tyrosine recombinase XerD; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family; integrase family protein 1672515..1673456 Spirochaeta smaragdinae DSM 11293 9489651 YP_003803278.1 CDS Spirs_1557 NC_014364.1 1673453 1674004 D COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; InterPro IPR001353; KEGG: tde:TDE1210 ATP-dependent protease peptidase subunit; PFAM: 20S proteasome A and subunit betas; SPTR: ATP-dependent protease HslVU, peptidase subunit; PFAM: Proteasome subunit; 20S proteasome subunits A and B 1673453..1674004 Spirochaeta smaragdinae DSM 11293 9489652 YP_003803279.1 CDS Spirs_1558 NC_014364.1 1674001 1675344 D COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; InterPro IPR004491:IPR011704:IPR013093:IPR003593; KEGG: tde:TDE1211 ATP-dependent protease ATP-binding subunit HslU; PFAM: ATPase AAA-2 domain protein; ATPase AAA; SMART: AAA ATPase; SPTR: ATP-dependent hsl protease ATP-binding subunit hslU; TIGRFAM: heat shock protein HslVU, ATPase HslU; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: heat shock protein HslVU, ATPase HslU; heat shock protein HslVU, ATPase HslU 1674001..1675344 Spirochaeta smaragdinae DSM 11293 9489653 YP_003803280.1 CDS Spirs_1559 NC_014364.1 1675398 1675814 D COGs: COG1815 flagellar basal body protein; InterPro IPR006300:IPR001444; KEGG: tde:TDE1212 flagellar basal-body rod protein FlgB; PFAM: flagellar basal body rod protein; SPTR: flagellar basal-body rod protein FlgB; TIGRFAM: flagellar basal-body rod protein FlgB; PFAM: Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgB; flagellar basal-body rod protein FlgB 1675398..1675814 Spirochaeta smaragdinae DSM 11293 9489654 YP_003803281.1 CDS Spirs_1560 NC_014364.1 1675829 1676287 D COGs: COG1558 flagellar basal body rod protein; InterPro IPR006299:IPR001444:IPR010930:IPR019776; KEGG: baf:BAPKO_0303 flagellar basal body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: flagellar basal-body rod protein FlgC; TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgC; flagellar basal-body rod protein FlgC 1675829..1676287 Spirochaeta smaragdinae DSM 11293 9489655 YP_003803282.1 CDS Spirs_1561 NC_014364.1 1676291 1676629 D InterPro IPR001624; KEGG: btu:BT0292 flagellar hook-basal body protein FliE; PFAM: flagellar hook-basal body complex protein FliE; SPTR: flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE; flagellar hook-basal body complex subunit FliE 1676291..1676629 Spirochaeta smaragdinae DSM 11293 9489656 YP_003803283.1 CDS Spirs_1562 NC_014364.1 1676696 1678405 D COGs: COG1766 flagellar biosynthesis/type III secretory pathway lipoprotein; InterPro IPR000067:IPR006182:IPR013556; KEGG: tpp:TPASS_0399 flagellar MS-ring protein; PFAM: flagellar M-ring domain protein; secretory protein YscJ/FliF family protein; SPTR: flagellar M-ring protein FliF; TIGRFAM: flagellar M-ring protein FliF; PFAM: flagellar M-ring protein C-terminal; Secretory protein of YscJ/FliF family; TIGRFAM: flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF); flagellar M-ring protein FliF 1676696..1678405 Spirochaeta smaragdinae DSM 11293 9489657 YP_003803284.1 CDS Spirs_1563 NC_014364.1 1678409 1679461 D COGs: COG1536 flagellar motor switch protein; InterPro IPR000090; KEGG: bhy:BHWA1_00668 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: flagellar motor switch protein FliG; TIGRFAM: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG; flagellar motor switch protein FliG 1678409..1679461 Spirochaeta smaragdinae DSM 11293 9489658 YP_003803285.1 CDS Spirs_1564 NC_014364.1 1679495 1680415 D COGs: COG1317 flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: tde:TDE1217 flagellar assembly protein H; PFAM: flagellar assembly protein FliH/type III secretion system HrpE; SPTR: flagellar assembly protein fliH, ; PFAM: flagellar assembly protein FliH; flagellar assembly protein FliH/type III secretion system HrpE 1679495..1680415 Spirochaeta smaragdinae DSM 11293 9489659 YP_003803286.1 CDS Spirs_1565 NC_014364.1 1680412 1681773 D COGs: COG1157 flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR005714:IPR020005:IPR004100:IPR000194:IPR 020003:IPR003593; KEGG: tde:TDE1218 flagellum-specific ATP synthase FliI; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SMART: AAA ATPase; SPTR: flagellar protein export ATPase FliI; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; flagellar protein export ATPase FliI; flagellar protein export ATPase FliI 1680412..1681773 Spirochaeta smaragdinae DSM 11293 9489660 YP_003803287.1 CDS Spirs_1566 NC_014364.1 1681748 1682188 D InterPro IPR012823; KEGG: dma:DMR_42100 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: flagellar export protein FliJ; PFAM: flagellar FliJ protein; TIGRFAM: flagellar export protein FliJ; flagellar export protein FliJ 1681748..1682188 Spirochaeta smaragdinae DSM 11293 9489661 YP_003803288.1 CDS Spirs_1567 NC_014364.1 1682192 1682809 D KEGG: tde:TDE1334 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1682192..1682809 Spirochaeta smaragdinae DSM 11293 9489662 YP_003803289.1 CDS Spirs_1568 NC_014364.1 1682833 1684257 D InterPro IPR001635; KEGG: bhy:BHWA1_02001 flagellar hook-length control domain containing protein; PFAM: flagellar hook-length control protein; SPTR: flagellar hook-length control protein; PFAM: flagellar hook-length control protein FliK; flagellar hook-length control protein 1682833..1684257 Spirochaeta smaragdinae DSM 11293 9489663 YP_003803290.1 CDS Spirs_1569 NC_014364.1 1684276 1684725 D COGs: COG1843 flagellar hook capping protein; InterPro IPR005648; KEGG: tde:TDE2769 flagellar basal body rod modification protein; PFAM: flagellar hook capping protein; SPTR: flagellar hook capping protein; PFAM: flagellar hook capping protein; flagellar hook capping protein 1684276..1684725 Spirochaeta smaragdinae DSM 11293 9489664 YP_003803291.1 CDS Spirs_1570 NC_014364.1 1684725 1686107 D COGs: COG1749 flagellar hook protein FlgE; InterProIPR020013:IPR001444:IPR011491:IPR010930:IPR 019776; KEGG: tpp:TPASS_0727 flagellar hook protein FlgE; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body FlaE domain protein; flagellar basal body rod protein; SPTR: flagellar hook protein flgE; TIGRFAM: fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins; fagellar hook-basal body protein 1684725..1686107 Spirochaeta smaragdinae DSM 11293 9489665 YP_003803292.1 CDS Spirs_1571 NC_014364.1 1686139 1686336 D COGs: COG1582 Uncharacterized protein possibly involved in motility; InterPro IPR009384; KEGG: tpp:TPASS_0726 flagellar protein; PFAM: flagellar FlbD family protein; SPTR: Orf4; initiates with GTG; PFAM: flagellar protein (FlbD); flagellar FlbD family protein 1686139..1686336 Spirochaeta smaragdinae DSM 11293 9489666 YP_003803293.1 CDS Spirs_1572 NC_014364.1 1686340 1687122 D COGs: COG1291 flagellar motor component; InterPro IPR002898:IPR000540; KEGG: nth:Nther_1402 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel 1686340..1687122 Spirochaeta smaragdinae DSM 11293 9489667 YP_003803294.1 CDS Spirs_1573 NC_014364.1 1687134 1687862 D COGs: COG1360 flagellar motor protein; InterPro IPR006665; KEGG: tde:TDE2765 flagellar motor protein MotB; PFAM: OmpA/MotB domain protein; SPTR: Chemotaxis protein MotB; PFAM: OmpA family; OmpA/MotB domain-containing protein 1687134..1687862 Spirochaeta smaragdinae DSM 11293 9489668 YP_003803295.1 CDS Spirs_1574 NC_014364.1 1687955 1688500 D COGs: COG1580 flagellar basal body-associated protein; InterPro IPR005503; KEGG: tpp:TPASS_0722 flagellar basal body-associated protein FliL; PFAM: flagellar basal body-associated protein FliL; SPTR: flagellar protein; PFAM: flagellar basal body-associated protein FliL; flagellar basal body-associated protein FliL 1687955..1688500 Spirochaeta smaragdinae DSM 11293 9489669 YP_003803296.1 CDS Spirs_1575 NC_014364.1 1688510 1689535 D COGs: COG1868 flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: tpp:TPASS_0721 flagellar motor switch protein FliM; PFAM: flagellar motor switch protein FliM; surface presentation of antigens (SPOA) protein; SPTR: flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; PFAM: Surface presentation of antigens (SPOA); flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM; flagellar motor switch protein FliM 1688510..1689535 Spirochaeta smaragdinae DSM 11293 9489670 YP_003803297.1 CDS Spirs_1576 NC_014364.1 1689537 1690664 D COGs: COG1886 flagellar motor switch/type III secretory pathway protein; InterPro IPR012826:IPR001172:IPR007597:IPR001543; KEGG: tde:TDE2762 flagellar motor switch protein FliY; PFAM: surface presentation of antigens (SPOA) protein; chemotaxis protein CheC; SPTR: flagellar motor switch protein FliY; TIGRFAM: flagellar motor switch protein FliN; PFAM: Surface presentation of antigens (SPOA); TIGRFAM: flagellar motor switch protein FliN; flagellar motor switch protein FliN 1689537..1690664 Spirochaeta smaragdinae DSM 11293 9489671 YP_003803298.1 CDS Spirs_1577 NC_014364.1 1690729 1691340 D KEGG: bhy:BHWA1_02629 hypothetical protein; SPTR: uncharacterized protein; PFAM: flagellar biosynthesis protein, FliO; hypothetical protein 1690729..1691340 Spirochaeta smaragdinae DSM 11293 9489672 YP_003803299.1 CDS Spirs_1578 NC_014364.1 1691337 1692119 D COGs: COG1338 flagellar biosynthesis pathway component FliP; InterPro IPR005837:IPR005838; KEGG: tpp:TPASS_0718 flagellar biosynthesis protein FliP; PFAM: type III secretion system inner membrane P protein; SPTR: flagellar biosynthetic protein FliP; TIGRFAM: flagellar biosynthetic protein FliP; PFAM: FliP family; TIGRFAM: flagellar biosynthetic protein FliP; flagellar biosynthetic protein FliP 1691337..1692119 Spirochaeta smaragdinae DSM 11293 9489673 YP_003803300.1 CDS Spirs_1579 NC_014364.1 1692131 1692400 D COGs: COG1987 flagellar biosynthesis pathway component FliQ; InterPro IPR006305:IPR002191; KEGG: bsu:BSU16360 flagellar biosynthesis protein FliQ; PFAM: export protein FliQ family 3; SPTR: flagellar biosynthetic protein FliQ; TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: Bacterial export proteins, family 3; TIGRFAM: flagellar biosynthetic protein FliQ; flagellar biosynthetic protein FliQ 1692131..1692400 Spirochaeta smaragdinae DSM 11293 9489674 YP_003803301.1 CDS Spirs_1580 NC_014364.1 1692409 1693209 D COGs: COG1684 flagellar biosynthesis pathway component FliR; InterPro IPR006303:IPR002010; KEGG: tpp:TPASS_0716 flagellar biosynthetic protein; PFAM: type III secretion system inner membrane R protein; SPTR: flagellar biosynthetic protein fliR; TIGRFAM: flagellar biosynthetic protein FliR; PFAM: Bacterial export proteins, family 1; TIGRFAM: flagellar biosynthetic protein FliR; flagellar biosynthetic protein FliR 1692409..1693209 Spirochaeta smaragdinae DSM 11293 9489675 YP_003803302.1 CDS Spirs_1581 NC_014364.1 1693206 1694345 D COGs: COG1377 flagellar biosynthesis pathway component FlhB; InterPro IPR006136:IPR006135; KEGG: tde:TDE0054 flagellar biosynthesis protein FlhB; PFAM: type III secretion exporter; SPTR: flagellar biosynthetic protein FlhB; TIGRFAM: flagellar biosynthetic protein FlhB; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flagellar biosynthetic protein FlhB; flagellar biosynthetic protein FlhB 1693206..1694345 Spirochaeta smaragdinae DSM 11293 9489676 YP_003803303.1 CDS Spirs_1582 NC_014364.1 1694370 1696460 D COGs: COG1298 flagellar biosynthesis pathway component FlhA; InterPro IPR006301:IPR001712; KEGG: btu:BT0271 flagellar biosynthesis protein FlhA; PFAM: type III secretion FHIPEP protein; SPTR: flagellar biosynthesis protein FlhA; TIGRFAM: flagellar biosynthesis protein FlhA; PFAM: FHIPEP family; TIGRFAM: flagellar biosynthesis protein FlhA; flagellar biosynthesis protein FlhA 1694370..1696460 Spirochaeta smaragdinae DSM 11293 9489677 YP_003803304.1 CDS Spirs_1583 NC_014364.1 1696482 1697687 D COGs: COG1419 flagellar GTP-binding protein; InterPro IPR020006:IPR000897:IPR019793:IPR003593; KEGG: baf:BAPKO_0280 flagellar biosynthesis regulator FlhF; PFAM: GTP-binding signal recognition particle SRP54 G- domain; SMART: ATPase AAA; SPTR: flagellar-associated GTP-binding protein; TIGRFAM: flagellar biosynthetic protein FlhF; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF; flagellar biosynthetic protein FlhF 1696482..1697687 Spirochaeta smaragdinae DSM 11293 9489678 YP_003803305.1 CDS Spirs_1584 NC_014364.1 1697690 1698559 D COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tpp:TPASS_0712 ATP-binding protein; PFAM: cobyrinic acid ac-diamide synthase; SPTR: ATP-binding protein (YlxH-1); PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase 1697690..1698559 Spirochaeta smaragdinae DSM 11293 9489679 YP_003803306.1 CDS Spirs_1585 NC_014364.1 1698614 1699228 D KEGG: tde:TDE2684 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1698614..1699228 Spirochaeta smaragdinae DSM 11293 9489680 YP_003803307.1 CDS Spirs_1586 NC_014364.1 1699232 1700020 D COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR014284:IPR012845:IPR000943:IPR007627:IPR 007624:IPR007630; KEGG: lic:LIC11380 RNA polymerase sigma factor WhiG; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 3 domain protein; SPTR: RNA polymerase sigma-D factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family; FliA/WhiG subfamily RNA polymerase sigma-28 subunit 1699232..1700020 Spirochaeta smaragdinae DSM 11293 9489681 YP_003803308.1 CDS Spirs_1587 NC_014364.1 1700037 1701983 D COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: tde:TDE2682 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF342); hypothetical protein 1700037..1701983 Spirochaeta smaragdinae DSM 11293 9489682 YP_003803309.1 CDS Spirs_1588 NC_014364.1 1701983 1702312 D KEGG: tde:TDE2681 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1701983..1702312 Spirochaeta smaragdinae DSM 11293 9489683 YP_003803310.1 CDS Spirs_1589 NC_014364.1 1702320 1702874 D KEGG: bhr:BH0265 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1702320..1702874 Spirochaeta smaragdinae DSM 11293 9489684 YP_003803311.1 CDS Spirs_1590 NC_014364.1 1702858 1704534 D COGs: COG0443 Molecular chaperone; InterPro IPR001023:IPR013126:IPR018181; KEGG: tit:Thit_0894 chaperone protein DnaK; PFAM: heat shock protein 70; SPTR: Chaperone protein DnaK; PFAM: Hsp70 protein; heat shock protein 70 1702858..1704534 Spirochaeta smaragdinae DSM 11293 9489685 YP_003803312.1 CDS Spirs_1591 NC_014364.1 1704527 1705159 D COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR003095:IPR001623:IPR017441; KEGG: rci:RCIX1090 Zn-finger protein interacting with DnaK (DnaJ-like); PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Predicted Zn-finger protein interacting with DnaK (DnaJ-like); PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 1704527..1705159 Spirochaeta smaragdinae DSM 11293 9489686 YP_003803313.1 CDS Spirs_1592 NC_014364.1 1705163 1707151 D COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR004358:IPR003594:IPR010916:IPR008207:IPR 005467; KEGG: tte:TTE1417 chemotaxis protein histidine kinase-like kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; Hpt domain protein; SPTR: Chemotaxis protein histidine kinase and related kinases; PFAM: P2 response regulator binding domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hpt domain; chemotaxis protein CheA 1705163..1707151 Spirochaeta smaragdinae DSM 11293 9489687 YP_003803314.1 CDS Spirs_1593 NC_014364.1 1707175 1708860 D COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR017871:IPR003593; KEGG: pca:Pcar_1361 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ATP-binding component of a transporter; PFAM: ABC transporter; ABC transporter 1707175..1708860 Spirochaeta smaragdinae DSM 11293 9489688 YP_003803315.1 CDS Spirs_1594 NC_014364.1 1708863 1709795 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: mma:MM_3131 fructokinase; PFAM: PfkB domain protein; SPTR: Fructokinase; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 1708863..1709795 Spirochaeta smaragdinae DSM 11293 9489689 YP_003803316.1 CDS Spirs_1595 NC_014364.1 1709758 1710123 R COGs: COG0662 mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: cth:Cthe_1305 cupin 2, barrel; PFAM: Cupin 2 conserved barrel domain protein; SPTR: uncharacterized protein; PFAM: Cupin domain; cupin complement(1709758..1710123) Spirochaeta smaragdinae DSM 11293 9489690 YP_003803317.1 CDS Spirs_1596 NC_014364.1 1710153 1712360 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004090:IPR003660:IPR004089; KEGG: tde:TDE0640 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1710153..1712360 Spirochaeta smaragdinae DSM 11293 9489691 YP_003803318.1 CDS Spirs_1597 NC_014364.1 1712357 1713325 R COGs: COG0142 geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: tit:Thit_2149 trans-hexaprenyltranstransferase; PFAM: polyprenyl synthetase; SPTR: trans-hexaprenyltranstransferase; PFAM: polyprenyl synthetase; polyprenyl synthetase complement(1712357..1713325) Spirochaeta smaragdinae DSM 11293 9489692 YP_003803319.1 CDS Spirs_1598 NC_014364.1 1713326 1715410 R COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: tte:TTE2486 NADH dehydrogenase, FAD-containing subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Pyridine nucleotide-disulfide oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(1713326..1715410) Spirochaeta smaragdinae DSM 11293 9489693 YP_003803320.1 CDS Spirs_1599 NC_014364.1 1715578 1716618 D COGs: COG1477 membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: tit:Thit_2148 ApbE family lipoprotein; PFAM: ApbE family lipoprotein; SPTR: ApbE family lipoprotein; PFAM: ApbE family; ApbE family lipoprotein 1715578..1716618 Spirochaeta smaragdinae DSM 11293 9489694 YP_003803321.1 CDS Spirs_1600 NC_014364.1 1716615 1716893 D KEGG: afv:AFLA_005610 NAP family protein; SPTR: Predicted protein; hypothetical protein 1716615..1716893 Spirochaeta smaragdinae DSM 11293 9489695 YP_003803322.1 CDS Spirs_1601 NC_014364.1 1716853 1717395 D COGs: COG4769 membrane protein; InterPro IPR014535:IPR010898; KEGG: tde:TDE1926 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: heptaprenyl diphosphate synthase component I; PFAM: Heptaprenyl diphosphate synthase component I; Heptaprenyl diphosphate synthase component I 1716853..1717395 Spirochaeta smaragdinae DSM 11293 9489696 YP_003803323.1 CDS Spirs_1602 NC_014364.1 1717417 1718016 D KEGG: tde:TDE1926 hypothetical protein; SPTR: heptaprenyl diphosphate synthase component I; manually curated; hypothetical protein 1717417..1718016 Spirochaeta smaragdinae DSM 11293 9489697 YP_003803324.1 CDS Spirs_1603 NC_014364.1 1718077 1718241 D hypothetical protein 1718077..1718241 Spirochaeta smaragdinae DSM 11293 9489698 YP_003803325.1 CDS Spirs_1604 NC_014364.1 1718377 1720053 D COGs: COG0028 thiamine pyrophosphate-requiring protein; InterProIPR012846:IPR012001:IPR012000:IPR011766:IPR 000399; KEGG: tnp:Tnap_0328 acetolactate synthase large subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme, central domain; thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase large subunit; acetolactate synthase, large subunit, biosynthetic type 1718377..1720053 Spirochaeta smaragdinae DSM 11293 9489699 YP_003803326.1 CDS Spirs_1605 NC_014364.1 1720074 1720583 D COGs: COG0440 acetolactate synthase small (regulatory) subunit; InterPro IPR004789:IPR002912:IPR019455; KEGG: tnp:Tnap_0329 acetolactate synthase, small subunit; PFAM: acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit; acetolactate synthase, small subunit 1720074..1720583 Spirochaeta smaragdinae DSM 11293 9489700 YP_003803327.1 CDS Spirs_1606 NC_014364.1 1720635 1721645 D COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013023:IPR013116:IPR000506; KEGG: trq:TRQ2_0387 ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase catalytic domain protein; acetohydroxy acid isomeroreductase; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: ketol-acid reductoisomerase; PFAM: acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase; ketol-acid reductoisomerase 1720635..1721645 Spirochaeta smaragdinae DSM 11293 9489701 YP_003803328.1 CDS Spirs_1607 NC_014364.1 1721712 1723451 D COGs: COG0129 dihydroxyacid dehydratase/phosphogluconate dehydratase; InterPro IPR004404:IPR000581:IPR020558; KEGG: tpt:Tpet_0369 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; PRIAM: dihydroxy-acid dehydratase; SPTR: dihydroxy-acid dehydratase; TIGRFAM: dihydroxy-acid dehydratase; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase; dihydroxy-acid dehydratase 1721712..1723451 Spirochaeta smaragdinae DSM 11293 9489702 YP_003803329.1 CDS Spirs_1608 NC_014364.1 1723448 1725124 D COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR005675:IPR000891:IPR013709:IPR002034; KEGG: tnp:Tnap_0332 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; PRIAM: (R)-citramalate synthase; SPTR: 2-isopropylmalate synthase/homocitrate synthase family protein; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; 2-isopropylmalate synthase/homocitrate synthase family protein 1723448..1725124 Spirochaeta smaragdinae DSM 11293 9489703 YP_003803330.1 CDS Spirs_1609 NC_014364.1 1725108 1726625 D COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR005671:IPR000891:IPR013709:IPR002034; KEGG: tna:CTN_0115 2-isopropylmalate synthase; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase; PFAM: LeuA allosteric (dimerisation) domain; HMGL-like; TIGRFAM: 2-isopropylmalate synthase, bacterial type; 2-isopropylmalate synthase 1725108..1726625 Spirochaeta smaragdinae DSM 11293 9489704 YP_003803331.1 CDS Spirs_1610 NC_014364.1 1726696 1727964 D COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterProIPR011826:IPR006251:IPR011823:IPR001030:IPR 018136; KEGG: trq:TRQ2_0383 3-isopropylmalate dehydratase, large subunit; PFAM: aconitate hydratase domain protein; SPTR: 3-isopropylmalate dehydratase, large subunit; TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; 3-isopropylmalate dehydratase; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein; 3-isopropylmalate dehydratase, large subunit 1726696..1727964 Spirochaeta smaragdinae DSM 11293 9489705 YP_003803332.1 CDS Spirs_1611 NC_014364.1 1727965 1728483 D COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR011824:IPR011827:IPR000573; KEGG: trq:TRQ2_0382 3-isopropylmalate dehydratase small subunit; PFAM: aconitate hydratase domain protein; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit; 3-isopropylmalate dehydratase, small subunit 1727965..1728483 Spirochaeta smaragdinae DSM 11293 9489706 YP_003803333.1 CDS Spirs_1612 NC_014364.1 1728480 1729541 D COGs: COG0473 isocitrate/isopropylmalate dehydrogenase; InterPro IPR004429:IPR001804:IPR019818; KEGG: tnp:Tnap_0336 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase 1728480..1729541 Spirochaeta smaragdinae DSM 11293 9489707 YP_003803334.1 CDS Spirs_1613 NC_014364.1 1729722 1730873 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR004358:IPR013656:IPR003661:IPR 003594:IPR005467:IPR000700; KEGG: rba:RB3779 histidine protein kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor signal transduction histidine kinase 1729722..1730873 Spirochaeta smaragdinae DSM 11293 9489708 YP_003803335.1 CDS Spirs_1614 NC_014364.1 1730878 1731225 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: cce:Ccel_1228 AraC family transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: HDOD domain family; PFAM: Response regulator receiver domain; response regulator receiver protein 1730878..1731225 Spirochaeta smaragdinae DSM 11293 9489709 YP_003803336.1 CDS Spirs_1615 NC_014364.1 1731222 1732838 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transporter; InterPro IPR004358:IPR003594:IPR005467; KEGG: tit:Thit_1844 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Multi-sensor signal transduction histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; histidine kinase 1731222..1732838 Spirochaeta smaragdinae DSM 11293 9489710 YP_003803337.1 CDS Spirs_1616 NC_014364.1 1732841 1733767 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_1605 response regulator receiver modulated metal dependent phosphohydrolase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Response regulator receiver domain; response regulator receiver protein 1732841..1733767 Spirochaeta smaragdinae DSM 11293 9489711 YP_003803338.1 CDS Spirs_1617 NC_014364.1 1733754 1735490 D COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: dap:Dacet_2839 hypothetical protein; PFAM: protein of unknown function DUF342; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF342); TIGRFAM: septum site-determining protein MinC; hypothetical protein 1733754..1735490 Spirochaeta smaragdinae DSM 11293 9489712 YP_003803339.1 CDS Spirs_1618 NC_014364.1 1735531 1736322 D COGs: COG3860 conserved hypothetical protein; InterPro IPR018656; KEGG: str:Sterm_2463 hypothetical protein; PFAM: protein of unknown function DUF2087; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2087); hypothetical protein 1735531..1736322 Spirochaeta smaragdinae DSM 11293 9489713 YP_003803340.1 CDS Spirs_1619 NC_014364.1 1736447 1737190 D COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: gyc:GYMC61_0406 transcriptional regulator, GntR family; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator 1736447..1737190 Spirochaeta smaragdinae DSM 11293 9489714 YP_003803341.1 CDS Spirs_1620 NC_014364.1 1737194 1738609 D COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: hor:Hore_19510 xylulokinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY 1737194..1738609 Spirochaeta smaragdinae DSM 11293 9489715 YP_003803342.1 CDS Spirs_1621 NC_014364.1 1738606 1739376 D COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: tde:TDE0076 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: fructose-bisphosphate aldolase; SPTR: Aldolase, DeoC/FbaB family; PFAM: DeoC/LacD family aldolase; fructose-bisphosphate aldolase 1738606..1739376 Spirochaeta smaragdinae DSM 11293 9489716 YP_003803343.1 CDS Spirs_1622 NC_014364.1 1739388 1740437 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149; KEGG: tde:TDE0075 sorbitol dehydrogenase, PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; SPTR: Sorbitol dehydrogenase, ; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 1739388..1740437 Spirochaeta smaragdinae DSM 11293 9489717 YP_003803344.1 CDS Spirs_1623 NC_014364.1 1740440 1741786 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ara:Arad_9887 sugar ABC transporter; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 1740440..1741786 Spirochaeta smaragdinae DSM 11293 9489718 YP_003803345.1 CDS Spirs_1624 NC_014364.1 1741871 1742764 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pmo:Pmob_0306 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1741871..1742764 Spirochaeta smaragdinae DSM 11293 9489719 YP_003803346.1 CDS Spirs_1625 NC_014364.1 1742766 1743608 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ara:Arad_9885 sugar ABC transporter; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1742766..1743608 Spirochaeta smaragdinae DSM 11293 9489720 YP_003803347.1 CDS Spirs_1626 NC_014364.1 1743668 1744177 R KEGG: rde:RD1_1546 nitrous-oxide reductase regulatory protein NosR; SPTR: glutaminyl-tRNA synthetase; hypothetical protein complement(1743668..1744177) Spirochaeta smaragdinae DSM 11293 9489721 YP_003803348.1 CDS Spirs_1627 NC_014364.1 1744364 1745596 D COGs: COG0303 Molybdopterin biosynthesis enzyme; InterProIPR020817:IPR005110:IPR001453:IPR005111:IPR 008284; KEGG: sro:Sros_8648 molybdopterin biosynthesis protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV; SPTR: Molybdopterin biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor synthesis protein 1744364..1745596 Spirochaeta smaragdinae DSM 11293 9489722 YP_003803349.1 CDS Spirs_1628 NC_014364.1 1745580 1746380 D COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR010505:IPR000385:IPR006638; KEGG: hmo:HM1_0064 molybdenum cofactor biosynthesis protein A; PFAM: radical SAM protein; molybdenum cofactor synthesis protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A; PFAM: Molybdenum Cofactor Synthesis C; radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial; radical SAM protein 1745580..1746380 Spirochaeta smaragdinae DSM 11293 9489723 YP_003803350.1 CDS Spirs_1629 NC_014364.1 1746383 1746877 D COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820; KEGG: bhy:BHWA1_00523 molybdenum cofactor biosynthesis protein C; PFAM: molybdopterin cofactor biosynthesis MoaC region; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: molybdenum cofactor biosynthesis protein C; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC; molybdenum cofactor biosynthesis protein C 1746383..1746877 Spirochaeta smaragdinae DSM 11293 9489724 YP_003803351.1 CDS Spirs_1630 NC_014364.1 1746874 1747800 D COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR020817:IPR005302:IPR001453; KEGG: cpy:Cphy_1481 molybdenum cofactor synthesis domain-containing protein; PFAM: MOSC domain containing protein; molybdopterin binding domain; SPTR: uncharacterized protein; TIGRFAM: molybdenum cofactor synthesis protein; PFAM: MOSC domain; Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor synthesis protein 1746874..1747800 Spirochaeta smaragdinae DSM 11293 9489725 YP_003803352.1 CDS Spirs_1631 NC_014364.1 1747797 1748399 R COGs: COG0406 fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: tkm:TK90_1453 phosphoglycerate mutase; PFAM: phosphoglycerate mutase; SPTR: phosphoglycerate mutase; PFAM: phosphoglycerate mutase family; phosphoglycerate mutase complement(1747797..1748399) Spirochaeta smaragdinae DSM 11293 9489726 YP_003803353.1 CDS Spirs_1632 NC_014364.1 1748401 1749141 R COGs: COG0368 Cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: rrs:RoseRS_4584 cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; SPTR: Cobalamin synthase; TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase; cobalamin 5'-phosphate synthase complement(1748401..1749141) Spirochaeta smaragdinae DSM 11293 9489727 YP_003803354.1 CDS Spirs_1633 NC_014364.1 1749138 1749701 R COGs: COG2087 adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: drm:Dred_1910 adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; SPTR: Cobalbumin biosynthesis protein; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase; cobalbumin biosynthesis protein complement(1749138..1749701) Spirochaeta smaragdinae DSM 11293 9489728 YP_003803355.1 CDS Spirs_1634 NC_014364.1 1749833 1751005 R COGs: COG4214 ABC-type xylose transporter permease component; InterPro IPR001851; KEGG: cce:Ccel_2684 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(1749833..1751005) Spirochaeta smaragdinae DSM 11293 9489729 YP_003803356.1 CDS Spirs_1635 NC_014364.1 1751002 1752552 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: cce:Ccel_2686 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(1751002..1752552) Spirochaeta smaragdinae DSM 11293 9489730 YP_003803357.1 CDS Spirs_1636 NC_014364.1 1752630 1753703 R COGs: COG4213 ABC-type xylose transporter periplasmic component; KEGG: gka:GK1910 ABC transporter substrate-binding protein; SPTR: ABC transporter substrate-binding protein; PFAM: family; ABC transporter substrate-binding protein complement(1752630..1753703) Spirochaeta smaragdinae DSM 11293 9489731 YP_003803358.1 CDS Spirs_1637 NC_014364.1 1753937 1754713 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: cce:Ccel_2688 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 1753937..1754713 Spirochaeta smaragdinae DSM 11293 9489732 YP_003803359.1 CDS Spirs_1638 NC_014364.1 1754716 1756212 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR003593; KEGG: cce:Ccel_2689 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter 1754716..1756212 Spirochaeta smaragdinae DSM 11293 9489733 YP_003803360.1 CDS Spirs_1639 NC_014364.1 1756181 1756459 R KEGG: dya:Dyak_GE13305 GE13305 gene product from transcript GE13305-RA; SPTR: Rho-type guanine exchange factor, isoform A; hypothetical protein complement(1756181..1756459) Spirochaeta smaragdinae DSM 11293 9489734 YP_003803361.1 CDS Spirs_1640 NC_014364.1 1756625 1757485 D COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR012165:IPR001433:IPR019480:IPR017927; KEGG: dap:Dacet_0222 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; oxidoreductase NAD-binding domain; oxidoreductase FAD/NAD(P)-binding domain-containing protein 1756625..1757485 Spirochaeta smaragdinae DSM 11293 9489735 YP_003803362.1 CDS Spirs_1641 NC_014364.1 1757482 1758972 D COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006004:IPR000759:IPR013027:IPR017896; KEGG: dap:Dacet_0223 glutamate synthase (NADPH), homotetrameric; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: glutamate synthase (NADPH), homotetrameric; TIGRFAM: glutamate synthase (NADPH), homotetrameric; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric; glutamate synthase (NADPH), homotetrameric 1757482..1758972 Spirochaeta smaragdinae DSM 11293 9489736 YP_003803363.1 CDS Spirs_1642 NC_014364.1 1759081 1759626 D COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: mxa:MXAN_1066 PTS system, IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS system, IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS IIA-like nitrogen-regulatory protein PtsN 1759081..1759626 Spirochaeta smaragdinae DSM 11293 9489737 YP_003803364.1 CDS Spirs_1643 NC_014364.1 1759608 1760225 R COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698:IPR018170; KEGG: mta:Moth_2140 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase; 5-formyltetrahydrofolate cyclo-ligase complement(1759608..1760225) Spirochaeta smaragdinae DSM 11293 9489738 YP_003803365.1 CDS Spirs_1644 NC_014364.1 1760231 1761406 R COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR010280:IPR002792; KEGG: geo:Geob_2786 RNA methyltransferase, TrmA family; PFAM: (uracil-5)-methyltransferase; SPTR: RNA methyltransferase, TrmA family; PFAM: tRNA (uracil-5-)-methyltransferase; TRAM domain; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA; (uracil-5)-methyltransferase complement(1760231..1761406) Spirochaeta smaragdinae DSM 11293 9489739 YP_003803366.1 CDS Spirs_1645 NC_014364.1 1761498 1763015 D COGs: COG0554 glycerol kinase; InterPro IPR005999:IPR018484:IPR018485:IPR018483; KEGG: drt:Dret_2094 glycerol kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: glycerol kinase; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; glycerol kinase 1761498..1763015 Spirochaeta smaragdinae DSM 11293 9489740 YP_003803367.1 CDS Spirs_1646 NC_014364.1 1763035 1764486 D COGs: COG1502 phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: str:Sterm_2322 phospholipase D/transphosphatidylase; PFAM: phospholipase D/transphosphatidylase; SMART: phospholipase D/transphosphatidylase; SPTR:phosphatidylserine/ phosphatidylglycerophosphate/ cardiolipin synthase; PFAM: phospholipase D Active site motif; phospholipase D/transphosphatidylase 1763035..1764486 Spirochaeta smaragdinae DSM 11293 9489741 YP_003803368.1 CDS Spirs_1647 NC_014364.1 1764548 1765372 D COGs: COG1624 conserved hypothetical protein; InterPro IPR014046:IPR003390; KEGG: tde:TDE1909 hypothetical protein; PFAM: protein of unknown function DUF147; SPTR: uncharacterized protein; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: conserved hypothetical protein TIGR00159; hypothetical protein 1764548..1765372 Spirochaeta smaragdinae DSM 11293 9489742 YP_003803369.1 CDS Spirs_1648 NC_014364.1 1765362 1766324 D COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: tde:TDE1908 hypothetical protein; PFAM: YbbR family protein; SPTR: uncharacterized protein; PFAM: YbbR-like protein; YbbR family protein 1765362..1766324 Spirochaeta smaragdinae DSM 11293 9489743 YP_003803370.1 CDS Spirs_1649 NC_014364.1 1766321 1766701 D COGs: COG0736 phosphopantetheinyl transferase (holo-ACP synthase); InterPro IPR002582:IPR004568:IPR008278; KEGG: tde:TDE1907 4'-phosphopantetheinyl transferase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase; holo-acyl-carrier-protein synthase 1766321..1766701 Spirochaeta smaragdinae DSM 11293 9489744 YP_003803371.1 CDS Spirs_1650 NC_014364.1 1766698 1767567 D COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: tde:TDE2274 hypothetical protein; PFAM: protein of unknown function DUF2225; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2225); hypothetical protein 1766698..1767567 Spirochaeta smaragdinae DSM 11293 9489745 YP_003803372.1 CDS Spirs_1651 NC_014364.1 1767587 1768330 D COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406:IPR020097; KEGG: afl:Aflv_0137 pseudouridylate synthase I; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; PRIAM: tRNA-pseudouridine synthase I; SPTR: Pseudouridylate synthase; TIGRFAM: tRNA pseudouridine synthase A; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I; tRNA pseudouridine synthase A 1767587..1768330 Spirochaeta smaragdinae DSM 11293 9489746 YP_003803373.1 CDS Spirs_1652 NC_014364.1 1768323 1769045 D COGs: COG1573 uracil-DNA glycosylase; InterPro IPR005273:IPR005122; KEGG: tde:TDE2491 DNA polymerase domain-containing protein; PFAM: uracil-DNA glycosylase superfamily; SPTR: DNA polymerase domain protein; TIGRFAM: phage SPO1 DNA polymerase-related protein; PFAM: uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase, family 4; phage SPO1 DNA polymerase-like protein 1768323..1769045 Spirochaeta smaragdinae DSM 11293 9489747 YP_003803374.1 CDS Spirs_1653 NC_014364.1 1769042 1771033 D COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterProIPR005259:IPR011545:IPR001650:IPR014001:IPR 014021; KEGG: tde:TDE2490 primosomal protein N'; PFAM: DEAD/DEAH box helicase domain protein; helicase; SMART: DEAD-like helicase ; helicase domain protein; SPTR: Primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N'; primosomal protein N' 1769042..1771033 Spirochaeta smaragdinae DSM 11293 9489748 YP_003803375.1 CDS Spirs_1654 NC_014364.1 1771081 1771566 D COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: btu:BT0065 peptide deformylase; PFAM: formylmethionine deformylase; SPTR: peptide deformylase; TIGRFAM: peptide deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase; peptide deformylase 1771081..1771566 Spirochaeta smaragdinae DSM 11293 9489749 YP_003803376.1 CDS Spirs_1655 NC_014364.1 1771566 1772513 D COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR005794:IPR002376:IPR005793; KEGG: tde:TDE1644 methionyl-tRNA formyltransferase; PFAM: formyl transferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: methionyl-tRNA formyltransferase; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 1771566..1772513 Spirochaeta smaragdinae DSM 11293 9489750 YP_003803377.1 CDS Spirs_1656 NC_014364.1 1772510 1773541 D COGs: COG2815 conserved hypothetical protein; InterPro IPR005543; KEGG: tde:TDE1643 PASTA domain-containing protein; PFAM: PASTA domain containing protein; SMART: PASTA domain containing protein; SPTR: Pasta domain protein; PFAM: PASTA domain; PASTA domain containing protein 1772510..1773541 Spirochaeta smaragdinae DSM 11293 9489751 YP_003803378.1 CDS Spirs_1657 NC_014364.1 1773799 1774659 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_1647 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1773799..1774659) Spirochaeta smaragdinae DSM 11293 9489753 YP_003803379.1 CDS Spirs_1658 NC_014364.1 1774652 1775557 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: cbe:Cbei_2358 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(1774652..1775557) Spirochaeta smaragdinae DSM 11293 9489754 YP_003803380.1 CDS Spirs_1659 NC_014364.1 1775629 1776936 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cbe:Cbei_2357 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein, family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(1775629..1776936) Spirochaeta smaragdinae DSM 11293 9489755 YP_003803381.1 CDS Spirs_1660 NC_014364.1 1776962 1778476 R COGs: COG3534 alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: gyc:GYMC61_2725 alpha-L-arabinofuranosidase domain protein; PFAM: alpha-L-arabinofuranosidase domain protein; SMART: alpha-L-arabinofuranosidase domain protein; SPTR: Arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase C-terminus; alpha-L-arabinofuranosidase domain-containing protein complement(1776962..1778476) Spirochaeta smaragdinae DSM 11293 9489756 YP_003803382.1 CDS Spirs_1661 NC_014364.1 1778564 1779841 R COGs: COG3395 conserved hypothetical protein; InterPro IPR010737:IPR016059; KEGG: pam:PANA_2458 YgbK; PFAM: type III effector Hrp-dependent outers; SPTR: YgbK; PFAM: protein of unknown function, DUF1537; type III effector Hrp-dependent outer protein complement(1778564..1779841) Spirochaeta smaragdinae DSM 11293 9489757 YP_003803383.1 CDS Spirs_1662 NC_014364.1 1780035 1781912 R COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterProIPR010524:IPR013767:IPR002078:IPR002197:IPR 003593; KEGG: dhd:Dhaf_1966 sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; PAS fold domain protein; Propionate catabolism activator domain protein; helix-turn-helix Fis-type; SMART: ATPase AAA; SPTR: Sigma54 specific transcriptional regulator, Fis family; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Propionate catabolism activator; TIGRFAM: PAS domain S-box; Fis family transcriptional regulator complement(1780035..1781912) Spirochaeta smaragdinae DSM 11293 9489758 YP_003803384.1 CDS Spirs_1663 NC_014364.1 1782445 1783977 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR000183:IPR003593; KEGG: clo:HMPREF0868_0026 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ribose import ATP-binding protein RbsA; PFAM: ABC transporter; ABC transporter 1782445..1783977 Spirochaeta smaragdinae DSM 11293 9489759 YP_003803385.1 CDS Spirs_1664 NC_014364.1 1783974 1784999 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: bcl:ABC0429 myo-inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: myo-inositol 2-dehydrogenase; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 1783974..1784999 Spirochaeta smaragdinae DSM 11293 9489760 YP_003803386.1 CDS Spirs_1665 NC_014364.1 1784999 1786030 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: gtn:GTNG_1814 ribose ABC transporter permease; PFAM: inner-membrane translocator; SPTR: ribose ABC transporter (Permease); PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 1784999..1786030 Spirochaeta smaragdinae DSM 11293 9489761 YP_003803387.1 CDS Spirs_1666 NC_014364.1 1786269 1787228 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761:IPR002198; KEGG: gtn:GTNG_1813 D-ribose-binding periplasmic protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: D-ribose-binding periplasmic protein; PFAM: family; periplasmic binding protein/LacI transcriptional regulator 1786269..1787228 Spirochaeta smaragdinae DSM 11293 9489762 YP_003803388.1 CDS Spirs_1667 NC_014364.1 1787387 1789315 D COGs: COG3829 transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR010524:IPR002078:IPR002197:IPR003593; KEGG: amt:Amet_0225 PAS/PAC sensor protein; PFAM: sigma-54 factor interaction domain-containing protein; Propionate catabolism activator domain protein; helix-turn-helix Fis-type; SMART: ATPase AAA; SPTR: PAS/PAC sensor protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Propionate catabolism activator; TIGRFAM: PAS domain S-box; Fis family transcriptional regulator 1787387..1789315 Spirochaeta smaragdinae DSM 11293 9489763 YP_003803389.1 CDS Spirs_1668 NC_014364.1 1789476 1790720 D COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: amt:Amet_0226 type III effector Hrp-dependent outers; PFAM: type III effector Hrp-dependent outers; SPTR: type III effector Hrp-dependent outers; PFAM: protein of unknown function, DUF1537; type III effector Hrp-dependent outer protein 1789476..1790720 Spirochaeta smaragdinae DSM 11293 9489764 YP_003803390.1 CDS Spirs_1669 NC_014364.1 1790742 1791893 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: ere:EUBREC_1203 alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 1790742..1791893 Spirochaeta smaragdinae DSM 11293 9489765 YP_003803391.1 CDS Spirs_1670 NC_014364.1 1791893 1792942 D COGs: COG1995 pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: ere:EUBREC_1204 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: pyridoxal phosphate biosynthetic protein PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; 4-hydroxythreonine-4-phosphate dehydrogenase 1791893..1792942 Spirochaeta smaragdinae DSM 11293 9489766 YP_003803392.1 CDS Spirs_1671 NC_014364.1 1792966 1793886 D COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220:IPR020625; KEGG: bcv:Bcav_1435 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase 1792966..1793886 Spirochaeta smaragdinae DSM 11293 9489767 YP_003803393.1 CDS Spirs_1672 NC_014364.1 1793883 1794866 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: msu:MS0068 SerA protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: SerA protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 1793883..1794866 Spirochaeta smaragdinae DSM 11293 9489768 YP_003803394.1 CDS Spirs_1673 NC_014364.1 1794882 1796057 D COGs: COG3964 amidohydrolase; InterPro IPR006680; KEGG: spq:SPAB_05554 metallo-dependent hydrolase; PFAM: amidohydrolase; SPTR: Predicted amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase 1794882..1796057 Spirochaeta smaragdinae DSM 11293 9489769 YP_003803395.1 CDS Spirs_1674 NC_014364.1 1796076 1797122 D COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR004682:IPR018389:IPR018103; KEGG: amt:Amet_0550 TRAP dicarboxylate transporter DctP subunit; PFAM: extracellular solute-binding protein, family 7; SPTR: TRAP dicarboxylate transporter DctP subunit; TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP 1796076..1797122 Spirochaeta smaragdinae DSM 11293 9489770 YP_003803396.1 CDS Spirs_1675 NC_014364.1 1797180 1797689 D COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: amt:Amet_0551 tripartite ATP-independent periplasmic transporter DctQ; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: tripartite ATP-independent periplasmic transporter DctQ component; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ component 1797180..1797689 Spirochaeta smaragdinae DSM 11293 9489771 YP_003803397.1 CDS Spirs_1676 NC_014364.1 1797690 1798973 D COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR004681:IPR010656; KEGG: amt:Amet_0552 TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP dicarboxylate transporter DctM subunit; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM 1797690..1798973 Spirochaeta smaragdinae DSM 11293 9489772 YP_003803398.1 CDS Spirs_1677 NC_014364.1 1799185 1801464 D COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: sat:SYN_01902 mannosyltransferase; PFAM: glycosyl transferase group 1; SPTR: mannosyltransferase; PFAM: glycosyl transferases group 1; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; group 1 glycosyl transferase 1799185..1801464 Spirochaeta smaragdinae DSM 11293 9489773 YP_003803399.1 CDS Spirs_1678 NC_014364.1 1801471 1802922 D COGs: COG2152 glycosylase; InterPro IPR007184; KEGG: rba:RB2988 hypothetical protein; PFAM: glycosidase related protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF377); glycosidase-like protein 1801471..1802922 Spirochaeta smaragdinae DSM 11293 9489774 YP_003803400.1 CDS Spirs_1679 NC_014364.1 1802926 1803939 D COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: dau:Daud_0862 glycosyl transferase, group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase, group 1; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase 1802926..1803939 Spirochaeta smaragdinae DSM 11293 9489775 YP_003803401.1 CDS Spirs_1680 NC_014364.1 1803991 1804446 D COGs: COG2731 beta-galactosidase subunit beta; InterPro IPR004375; KEGG: tbd:Tbd_2429 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF386); TIGRFAM: conserved hypothetical protein; hypothetical protein 1803991..1804446 Spirochaeta smaragdinae DSM 11293 9489776 YP_003803402.1 CDS Spirs_1681 NC_014364.1 1804553 1806109 D COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: hor:Hore_19140 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter family; Na+/H+ antiporter NhaC 1804553..1806109 Spirochaeta smaragdinae DSM 11293 9489777 YP_003803403.1 CDS Spirs_1682 NC_014364.1 1806130 1806684 R COGs: COG2716 glycine cleavage system regulatory protein; InterPro IPR016867:IPR002912; KEGG: alv:Alvin_2004 amino acid-binding ACT domain protein; PFAM: amino acid-binding ACT domain protein; SPTR: ACT domain protein; PFAM: ACT domain; amino acid-binding ACT domain-containing protein complement(1806130..1806684) Spirochaeta smaragdinae DSM 11293 9489778 YP_003803404.1 CDS Spirs_1683 NC_014364.1 1806805 1807557 R KEGG: ana:alr3863 hypothetical protein; SPTR: Haloacid dehalogenase-like hydrolase; hypothetical protein complement(1806805..1807557) Spirochaeta smaragdinae DSM 11293 9489779 YP_003803405.1 CDS Spirs_1684 NC_014364.1 1807562 1808473 R COGs: COG1045 serine acetyltransferase; InterPro IPR001451; KEGG: mbu:Mbur_0414 serine O-acetyltransferase; PRIAM: serine O-acetyltransferase; SPTR: serine O-acetyltransferase; TIGRFAM: serine O-acetyltransferase; serine O-acetyltransferase complement(1807562..1808473) Spirochaeta smaragdinae DSM 11293 9489780 YP_003803406.1 CDS Spirs_1685 NC_014364.1 1808758 1809213 D COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: ddf:DEFDS_1576 heat shock protein Hsp20; PFAM: heat shock protein Hsp20; SPTR: Strongly similar to small heat shock protein; PFAM: Hsp20/alpha crystallin family; heat shock protein Hsp20 1808758..1809213 Spirochaeta smaragdinae DSM 11293 9489781 YP_003803407.1 CDS Spirs_1686 NC_014364.1 1809231 1809566 D COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: srm:SRM_02579 heat shock protein; PFAM: heat shock protein Hsp20; SPTR: heat shock protein Hsp20; PFAM: Hsp20/alpha crystallin family; heat shock protein Hsp20 1809231..1809566 Spirochaeta smaragdinae DSM 11293 9489782 YP_003803408.1 CDS Spirs_1687 NC_014364.1 1809625 1810089 R COGs: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerase 2; InterPro IPR001179; KEGG: csa:Csal_1297 peptidylprolyl isomerase, FKBP-type; PFAM: peptidylprolyl isomerase FKBP-type; PRIAM: peptidylprolyl isomerase; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; peptidylprolyl isomerase complement(1809625..1810089) Spirochaeta smaragdinae DSM 11293 9489783 YP_003803409.1 CDS Spirs_1688 NC_014364.1 1810214 1813072 D COGs: COG0612 Zn-dependent peptidase; InterPro IPR011765:IPR007863:IPR001431; KEGG: cts:Ctha_1907 peptidase M16 domain protein; PFAM: peptidase M16 domain protein; SPTR: peptidase M16 domain protein; PFAM: peptidase M16 inactive domain; Insulinase (peptidase family M16); peptidase M16 domain-containing protein 1810214..1813072 Spirochaeta smaragdinae DSM 11293 9489784 YP_003803410.1 CDS Spirs_1689 NC_014364.1 1813078 1813725 R COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718:IPR003781; KEGG: cth:Cthe_0422 redox-sensing transcriptional repressor REX; PFAM: CoA-binding protein; Rex DNA-binding domain protein; SPTR: CoA-binding protein; PFAM: CoA binding domain; DNA-binding protein N-terminus; CoA-binding protein complement(1813078..1813725) Spirochaeta smaragdinae DSM 11293 9489785 YP_003803411.1 CDS Spirs_1690 NC_014364.1 1813853 1819099 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR004358:IPR017442:IPR003018:IPR003661:IPR 003594:IPR008266:IPR020635:IPR002290:IPR000719:IPR005467; KEGG: npu:Npun_R2272 multi-sensor signal transduction multi-kinase; PFAM: ATP-binding region ATPase domain protein; serine/threonine-protein kinase-like domain; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; serine/threonine protein kinase; Tyrosine-protein kinase, subgroup, catalytic domain; GAF domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: protein kinase domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; GAF domain; His Kinase A (phosphoacceptor) domain; multi-sensor signal transduction multi-kinase 1813853..1819099 Spirochaeta smaragdinae DSM 11293 9489786 YP_003803412.1 CDS Spirs_1691 NC_014364.1 1819123 1820748 R COGs: COG0455 ATPase involved in chromosome partitioning; KEGG: apb:SAR116_0864 ATPase; SPTR: uncharacterized protein; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; ATPase involved in chromosome partitioning complement(1819123..1820748) Spirochaeta smaragdinae DSM 11293 9489787 YP_003803413.1 CDS Spirs_1692 NC_014364.1 1820815 1821843 D COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR001789; KEGG: bba:Bd0367 two component response regulator; PFAM: GGDEF domain containing protein; response regulator receiver; SMART: GGDEF domain containing protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; response regulator receiver modulated diguanylate cyclase 1820815..1821843 Spirochaeta smaragdinae DSM 11293 9489788 YP_003803414.1 CDS Spirs_1693 NC_014364.1 1821850 1822824 R COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003439:IPR017871:IPR003593; KEGG: tko:TK0158 ABC-type iron(III) transporter, ATPase component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC-type iron(III) transport system, ATPase component; PFAM: ABC transporter; ABC transporter complement(1821850..1822824) Spirochaeta smaragdinae DSM 11293 9489789 YP_003803415.1 CDS Spirs_1694 NC_014364.1 1822826 1824520 R COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: ton:TON_1959 ABC-type iron(III) transport system, permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: sulfate transporter permease protein; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: thiamine ABC transporter permease; binding-protein-dependent transporters inner membrane component complement(1822826..1824520) Spirochaeta smaragdinae DSM 11293 9489790 YP_003803416.1 CDS Spirs_1695 NC_014364.1 1824517 1825536 R COGs: COG4143 ABC-type thiamine transporter periplasmic component; InterPro IPR005948:IPR006059; KEGG: tde:TDE0143 thiamine ABC transporter thiamine-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: thiamine-binding periplasmic protein; TIGRFAM: ABC transporter periplasmic binding protein, thiB subfamily; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: thiamine ABC transporter periplasmic binding protein; ABC transporter periplasmic binding protein, thiB subfamily; thiamine ABC transporter periplasmic protein complement(1824517..1825536) Spirochaeta smaragdinae DSM 11293 9489791 YP_003803417.1 CDS Spirs_1696 NC_014364.1 1825722 1827533 R COGs: COG5002 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR013767:IPR003661:IPR 003594:IPR000014:IPR005467; KEGG: pca:Pcar_0654 two-component sensor histidine kinase PhoR; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor signal transduction histidine kinase complement(1825722..1827533) Spirochaeta smaragdinae DSM 11293 9489792 YP_003803418.1 CDS Spirs_1697 NC_014364.1 1827554 1828252 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: dol:Dole_1930 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator complement(1827554..1828252) Spirochaeta smaragdinae DSM 11293 9489793 YP_003803419.1 CDS Spirs_1698 NC_014364.1 1828263 1828931 R COGs: COG0704 phosphate uptake regulator; InterPro IPR008170; KEGG: tpd:Teth39_0831 phosphate uptake regulator, PhoU; PFAM: PhoU family protein; SPTR: phosphate uptake regulator, PhoU; TIGRFAM: phosphate transporter regulatory protein PhoU; PFAM: PhoU domain; TIGRFAM: phosphate transporter regulatory protein PhoU; phosphate uptake regulator PhoU complement(1828263..1828931) Spirochaeta smaragdinae DSM 11293 9489794 YP_003803420.1 CDS Spirs_1699 NC_014364.1 1828961 1829746 R COGs: COG1117 ABC-type phosphate transporter ATPase component; InterProIPR005670:IPR003439:IPR017871:IPR003593:IPR 015850; KEGG: tte:TTE1628 ABC-type phosphate transporter, ATPase component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: phosphate import ATP-binding protein pstB 2; TIGRFAM: phosphate ABC transporter ATPase; PFAM: ABC transporter; TIGRFAM: phosphate ABC transporter ATP-binding protein; phosphate ABC transporter ATPase complement(1828961..1829746) Spirochaeta smaragdinae DSM 11293 9489795 YP_003803421.1 CDS Spirs_1700 NC_014364.1 1829767 1831413 R COGs: COG0581 ABC-type phosphate transporter permease; InterPro IPR005672:IPR000515; KEGG: bre:BRE_217 phosphate ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: phosphate ABC transporter permease protein; TIGRFAM: phosphate ABC transporter inner membrane subunit PstA; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: phosphate ABC transporter permease PstA; phosphate ABC transporter inner membrane subunit PstA complement(1829767..1831413) Spirochaeta smaragdinae DSM 11293 9489796 YP_003803422.1 CDS Spirs_1701 NC_014364.1 1831410 1832303 R COGs: COG0573 ABC-type phosphate transporter permease; InterPro IPR011864:IPR000515; KEGG: csc:Csac_1611 phosphate ABC transporter inner membrane subunit PstC; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: phosphate ABC transporter inner membrane subunit PstC; TIGRFAM: phosphate ABC transporter inner membrane subunit PstC; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: phosphate ABC transporter permease PstC; phosphate ABC transporter permease PstA; phosphate ABC transporter inner membrane subunit PstC complement(1831410..1832303) Spirochaeta smaragdinae DSM 11293 9489797 YP_003803423.1 CDS Spirs_1702 NC_014364.1 1832461 1833315 R COGs: COG0226 ABC-type phosphate transporter periplasmic component; InterPro IPR011862:IPR006059; KEGG: dde:Dde_1062 phosphate binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: phosphate binding protein; TIGRFAM: phosphate binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: phosphate binding protein; phosphate binding protein complement(1832461..1833315) Spirochaeta smaragdinae DSM 11293 9489798 YP_003803424.1 CDS Spirs_1703 NC_014364.1 1833447 1834565 R KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein complement(1833447..1834565) Spirochaeta smaragdinae DSM 11293 9489799 YP_003803425.1 CDS Spirs_1704 NC_014364.1 1834662 1835354 R KEGG: mvn:Mevan_0475 CoB--CoM heterodisulfide reductase; SPTR: Leptin-I; hypothetical protein complement(1834662..1835354) Spirochaeta smaragdinae DSM 11293 9489800 YP_003803426.1 CDS Spirs_1705 NC_014364.1 1835496 1836617 D COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR006009:IPR004276:IPR007235; KEGG: tde:TDE1974 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; PFAM: glycosyl transferase family 28; glycosyltransferase 28 domain; SPTR: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; TIGRFAM:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: glycosyltransferase family 28 C-terminal domain; glycosyltransferase family 28 N-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 1835496..1836617 Spirochaeta smaragdinae DSM 11293 9489801 YP_003803427.1 CDS Spirs_1706 NC_014364.1 1836630 1837124 D InterPro IPR003825; KEGG: tde:TDE1973 CvpA family protein; PFAM: colicin V production protein; SPTR: CvpA family protein; PFAM: colicin V production protein; colicin V production protein 1836630..1837124 Spirochaeta smaragdinae DSM 11293 9489802 YP_003803428.1 CDS Spirs_1707 NC_014364.1 1837117 1838334 D COGs: COG2812 DNA polymerase III gamma/tau subunits; KEGG: tde:TDE1971 DNA polymerase III domain-containing protein; SPTR: DNA polymerase III domain protein; DNA polymerase III gamma/tau subunits 1837117..1838334 Spirochaeta smaragdinae DSM 11293 9489803 YP_003803429.1 CDS Spirs_1708 NC_014364.1 1838327 1839490 D COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR004358:IPR013656:IPR003661:IPR 003594:IPR005467; KEGG: tde:TDE1970 sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor signal transduction histidine kinase 1838327..1839490 Spirochaeta smaragdinae DSM 11293 9489804 YP_003803430.1 CDS Spirs_1709 NC_014364.1 1839494 1840855 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterProIPR020441:IPR001789:IPR002078:IPR002197:IPR 003593; KEGG: tde:TDE1969 sigma-54 dependent transcriptional regulator/response regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; ATPase AAA; SPTR: Sigma-54 dependent transcriptional regulator/response regulator; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Fis family transcriptional regulator 1839494..1840855 Spirochaeta smaragdinae DSM 11293 9489805 YP_003803431.1 CDS Spirs_1710 NC_014364.1 1840852 1841307 R InterPro IPR001623; KEGG: hoh:Hoch_4820 heat shock protein DnaJ domain protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: heat shock protein DnaJ domain protein; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein complement(1840852..1841307) Spirochaeta smaragdinae DSM 11293 9489806 YP_003803432.1 CDS Spirs_1711 NC_014364.1 1841291 1842163 R KEGG: pth:PTH_1800 diaminopimelate epimerase; SPTR: diaminopimelate epimerase; hypothetical protein complement(1841291..1842163) Spirochaeta smaragdinae DSM 11293 9489807 YP_003803433.1 CDS Spirs_1712 NC_014364.1 1842244 1844673 D COGs: COG1199 Rad3-related DNA helicase; InterProIPR001405:IPR014001:IPR006555:IPR014013:IPR 001650; KEGG: pca:Pcar_0023 Rad3-related DNA helicases; SMART: helicase c2; DEAD-like helicase; SPTR: Rad3-related DNA helicases; manually curated; PFAM: DEAD/DEAH box helicase; TIGRFAM: DnaQ family exonuclease/DinG family helicase; helicase c2 1842244..1844673 Spirochaeta smaragdinae DSM 11293 9489808 YP_003803434.1 CDS Spirs_1713 NC_014364.1 1844902 1845165 R COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR001476:IPR020818:IPR018369; KEGG: tde:TDE0934 co-chaperonin GroES; PFAM: chaperonin Cpn10; SPTR: 10 kDa chaperonin; PFAM: chaperonin 10 Kd subunit; chaperonin Cpn10 complement(1844902..1845165) Spirochaeta smaragdinae DSM 11293 9489809 YP_003803435.1 CDS Spirs_1714 NC_014364.1 1845329 1845676 D KEGG: ago:AGOS_AGR382W AGR382Wp; SPTR: L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase; hypothetical protein 1845329..1845676 Spirochaeta smaragdinae DSM 11293 9489810 YP_003803436.1 CDS Spirs_1715 NC_014364.1 1845884 1846759 D COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR000943:IPR009042:IPR007627:IPR 007624:IPR007630; KEGG: tde:TDE0937 RNA polymerase sigma-70 factor family protein; PFAM: sigma-70 region 4 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 3 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 1845884..1846759 Spirochaeta smaragdinae DSM 11293 9489811 YP_003803437.1 CDS Spirs_1716 NC_014364.1 1846938 1849604 D COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR010121:IPR002192:IPR008279:IPR000121:IPR 018274; KEGG: ddf:DEFDS_0235 pyruvate phosphate dikinase; PFAM: pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; PEP-utilizing protein; PRIAM: pyruvate, phosphate dikinase; SPTR: pyruvate phosphate dikinase; TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; pyruvate, phosphate dikinase 1846938..1849604 Spirochaeta smaragdinae DSM 11293 9489812 YP_003803438.1 CDS Spirs_1717 NC_014364.1 1849691 1850413 D COGs: COG2231 Uncharacterized protein related to endonuclease III; InterPro IPR003265:IPR003651; KEGG: mmx:MmarC6_0307 HhH-GPD family protein; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; SMART: HhH-GPD family protein; SPTR: HhH-GPD family protein; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; HhH-GPD family protein 1849691..1850413 Spirochaeta smaragdinae DSM 11293 9489813 YP_003803439.1 CDS Spirs_1718 NC_014364.1 1850513 1852147 D COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593; KEGG: gme:Gmet_2630 ABC transporter-related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter-related protein; PFAM: ABC transporter; ABC transporter 1850513..1852147 Spirochaeta smaragdinae DSM 11293 9489814 YP_003803440.1 CDS Spirs_1719 NC_014364.1 1852198 1853457 R COGs: COG0452 phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR005252:IPR003382:IPR007085; KEGG: ton:TON_0798 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; PFAM: DNA/pantothenate metabolism flavoprotein domain protein; flavoprotein; PRIAM: phosphopantothenate--cysteine ligase; SPTR: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic; phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase complement(1852198..1853457) Spirochaeta smaragdinae DSM 11293 9489815 YP_003803441.1 CDS Spirs_1720 NC_014364.1 1853454 1854632 R COGs: COG0076 glutamate decarboxylase and related PLP-dependent protein; InterPro IPR002129:IPR018486; KEGG: ton:TON_1710 L-tyrosine decarboxylase; PFAM: pyridoxal-dependent decarboxylase; SPTR: glutamate decarboxylase; PFAM: pyridoxal-dependent decarboxylase conserved domain; pyridoxal-dependent decarboxylase complement(1853454..1854632) Spirochaeta smaragdinae DSM 11293 9489816 YP_003803442.1 CDS Spirs_1721 NC_014364.1 1854643 1855425 R COGs: COG0413 Ketopantoate hydroxymethyltransferase; InterPro IPR003700; KEGG: dps:DP2907 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; PRIAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; SPTR: 3-methyl-2-oxobutanoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; PFAM: Ketopantoate hydroxymethyltransferase; TIGRFAM: 3-methyl-2-oxobutanoate hydroxymethyltransferase; 3-methyl-2-oxobutanoatehydroxymethyltransferase complement(1854643..1855425) Spirochaeta smaragdinae DSM 11293 9489817 YP_003803443.1 CDS Spirs_1722 NC_014364.1 1855422 1856192 R COGs: COG1701 conserved hypothetical protein; InterPro IPR002855; KEGG: dka:DKAM_0336 hypothetical protein; PFAM: protein of unknown function DUF137; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF137; hypothetical protein complement(1855422..1856192) Spirochaeta smaragdinae DSM 11293 9489818 YP_003803444.1 CDS Spirs_1723 NC_014364.1 1856185 1857126 R COGs: COG1829 kinase (sugar kinase superfamily); InterPro IPR012043:IPR006204:IPR013750; KEGG: mpd:MCP_2676 hypothetical protein; PFAM: GHMP kinase; GHMP kinase domain protein; SPTR: GHMP kinases ATP-binding protein; PFAM: GHMP kinases N terminal domain; GHMP kinase complement(1856185..1857126) Spirochaeta smaragdinae DSM 11293 9489819 YP_003803445.1 CDS Spirs_1724 NC_014364.1 1857191 1858930 D InterPro IPR002372:IPR018391; KEGG: mac:MA3699 cell surface protein; PFAM: pyrrolo-quinoline quinone; SPTR: cell surface protein; pyrrolo-quinoline quinone 1857191..1858930 Spirochaeta smaragdinae DSM 11293 9489820 YP_003803446.1 CDS Spirs_1725 NC_014364.1 1858966 1860573 D InterPro IPR007926; KEGG: tde:TDE2699 antigen, PFAM: P83100 family protein; SPTR: antigen, ; PFAM: Borrelia P83/100 protein; P83100 family protein 1858966..1860573 Spirochaeta smaragdinae DSM 11293 9489821 YP_003803447.1 CDS Spirs_1726 NC_014364.1 1860596 1861036 R InterPro IPR003115; KEGG: tde:TDE2187 ParB-like nuclease domain-containing protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB-like nuclease domain protein; PFAM: ParB-like nuclease domain; ParB domain-containing protein nuclease complement(1860596..1861036) Spirochaeta smaragdinae DSM 11293 9489822 YP_003803448.1 CDS Spirs_1727 NC_014364.1 1861055 1863547 R COGs: COG5009 membrane carboxypeptidase/penicillin-binding protein; InterPro IPR011816:IPR001264:IPR001460; KEGG: bre:BRE_738 penicillin-binding protein; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; PRIAM: peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein; TIGRFAM: penicillin-binding protein, 1A family; PFAM: Penicillin binding protein transpeptidase domain; transglycosylase; TIGRFAM: penicillin-binding protein, 1A family; penicillin-binding protein, 1A family complement(1861055..1863547) Spirochaeta smaragdinae DSM 11293 9489823 YP_003803449.1 CDS Spirs_1728 NC_014364.1 1863655 1863825 D KEGG: tva:TVAG_178570 hypothetical protein; hypothetical protein 1863655..1863825 Spirochaeta smaragdinae DSM 11293 9489824 YP_003803450.1 CDS Spirs_1729 NC_014364.1 1863745 1864740 R InterPro IPR013229; KEGG: tga:TGAM_1390 amylopullulanase related protein (Apu); PFAM: PEGA domain protein; SPTR: uncharacterized protein; PEGA domain-containing protein complement(1863745..1864740) Spirochaeta smaragdinae DSM 11293 9489825 YP_003803451.1 CDS Spirs_1730 NC_014364.1 1864737 1865645 R COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047; KEGG: tde:TDE1738 M23/M37 peptidase domain-containing protein; PFAM: peptidase M23; peptidoglycan-binding lysin domain; SPTR: M23/M37 peptidase domain protein; PFAM: peptidase family M23; peptidase M23 complement(1864737..1865645) Spirochaeta smaragdinae DSM 11293 9489826 YP_003803452.1 CDS Spirs_1731 NC_014364.1 1865645 1866076 R KEGG: sds:SDEG_0896 xanthine permease; SPTR: uncharacterized protein; hypothetical protein complement(1865645..1866076) Spirochaeta smaragdinae DSM 11293 9489827 YP_003803453.1 CDS Spirs_1732 NC_014364.1 1866060 1867043 R InterPro IPR001440:IPR019734:IPR013026; KEGG: gur:Gura_1893 hypothetical protein; PFAM: TPR repeat-containing protein; SPTR: hypothetical protein; hypothetical protein complement(1866060..1867043) Spirochaeta smaragdinae DSM 11293 9489828 YP_003803454.1 CDS Spirs_1733 NC_014364.1 1867043 1868059 R COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: cts:Ctha_2172 mammalian cell entry related domain protein; PFAM: Mammalian cell entry related domain protein; SPTR: Mammalian cell entry related domain protein; PFAM: mce related protein; hypothetical protein complement(1867043..1868059) Spirochaeta smaragdinae DSM 11293 9489829 YP_003803455.1 CDS Spirs_1734 NC_014364.1 1868114 1868896 R COGs: COG1135 ABC-type metal ion transporter ATPase component; InterPro IPR003439:IPR017871:IPR000408:IPR003593; KEGG: chy:CHY_0167 cell division ATP-binding protein FtsE; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Predicted ATPase involved in cell division; PFAM: ABC transporter; ABC transporter complement(1868114..1868896) Spirochaeta smaragdinae DSM 11293 9489830 YP_003803456.1 CDS Spirs_1735 NC_014364.1 1868908 1869684 R COGs: COG0767 ABC-type transporter involved in resistance to organic solvents permease; InterPro IPR003453; KEGG: cts:Ctha_2170 protein of unknown function DUF140; PFAM: protein of unknown function DUF140; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein; hypothetical protein complement(1868908..1869684) Spirochaeta smaragdinae DSM 11293 9489831 YP_003803457.1 CDS Spirs_1736 NC_014364.1 1869824 1870804 D COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterProIPR000595:IPR001440:IPR013105:IPR019734:IPR 013026; KEGG: bhy:BHWA1_00483 cAMP-binding protein; PFAM: cyclic nucleotide-binding; TPR repeat-containing protein; hypothetical protein; SPTR: Cyclic nucleotide-binding protein with tetratricopeptide repeat; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator 1869824..1870804 Spirochaeta smaragdinae DSM 11293 9489832 YP_003803458.1 CDS Spirs_1737 NC_014364.1 1870801 1871451 D COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR002373:IPR000595:IPR018488; KEGG: tde:TDE2616 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator 1870801..1871451 Spirochaeta smaragdinae DSM 11293 9489833 YP_003803459.1 CDS Spirs_1738 NC_014364.1 1871785 1872168 D KEGG: sus:acid_0629 phage integrase family protein; SPTR: Phage integrase; PFAM: Phage integrase family; hypothetical protein 1871785..1872168 Spirochaeta smaragdinae DSM 11293 9489835 YP_003803460.1 CDS Spirs_1740 NC_014364.1 1873529 1874080 D COGs: COG4283 conserved hypothetical protein; InterPro IPR012550; KEGG: pgn:PGN_1352 hypothetical protein; PFAM: protein of unknown function DUF1706; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1706); hypothetical protein 1873529..1874080 Spirochaeta smaragdinae DSM 11293 9489837 YP_003803461.1 CDS Spirs_1741 NC_014364.1 1874306 1874569 D COGs: COG1802 transcriptional regulators; InterPro IPR011711; KEGG: vpr:Vpar_1548 GntR family transcriptional regulator; PFAM: GntR family transcriptional regulator; SPTR: uncharacterized protein; PFAM: FCD domain; GntR family transcriptional regulator 1874306..1874569 Spirochaeta smaragdinae DSM 11293 9489838 YP_003803462.1 CDS Spirs_1742 NC_014364.1 1874651 1875421 R InterPro IPR006260; KEGG: azl:AZL_007860 protein; SPTR: TonB family protein; TIGRFAM: TonB family protein; manually curated; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; TonB family protein complement(1874651..1875421) Spirochaeta smaragdinae DSM 11293 9489839 YP_003803463.1 CDS Spirs_1743 NC_014364.1 1875405 1875806 R COGs: COG0848 biopolymertransporter; InterPro IPR003400; KEGG: afw:Anae109_0872 biopolymer transporter ExbD/TolR; PFAM: biopolymertransporter ExbD/TolR; SPTR: biopolymertransporter ExbD/TolR family; PFAM: biopolymertransporter ExbD/TolR; biopolymertransporter ExbD/TolR complement(1875405..1875806) Spirochaeta smaragdinae DSM 11293 9489840 YP_003803464.1 CDS Spirs_1744 NC_014364.1 1875808 1876536 R COGs: COG0811 biopolymertransporter; InterPro IPR002898; KEGG: hba:Hbal_2532 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel complement(1875808..1876536) Spirochaeta smaragdinae DSM 11293 9489841 YP_003803465.1 CDS Spirs_1745 NC_014364.1 1876579 1876989 R KEGG: ckr:CKR_0697 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1876579..1876989) Spirochaeta smaragdinae DSM 11293 9489842 YP_003803466.1 CDS Spirs_1746 NC_014364.1 1877002 1878975 R COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: lic:LIC20151 TonB-dependent outer membrane receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; SPTR: TonB-dependent outer membrane receptor; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor; TonB-dependent receptor complement(1877002..1878975) Spirochaeta smaragdinae DSM 11293 9489843 YP_003803467.1 CDS Spirs_1747 NC_014364.1 1879218 1880273 R KEGG: dth:DICTH_0567 methylcobamide:CoM methyltransferase MtbA, SPTR: methylcobamide:CoM methyltransferase MtbA, ; PFAM: uroporphyrinogen decarboxylase (URO-D); hypothetical protein complement(1879218..1880273) Spirochaeta smaragdinae DSM 11293 9489844 YP_003803468.1 CDS Spirs_1748 NC_014364.1 1880509 1881405 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: oih:OB0775 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1880509..1881405 Spirochaeta smaragdinae DSM 11293 9489845 YP_003803469.1 CDS Spirs_1749 NC_014364.1 1881416 1882261 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: sma:SAV_2249 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1881416..1882261 Spirochaeta smaragdinae DSM 11293 9489846 YP_003803470.1 CDS Spirs_1750 NC_014364.1 1882279 1883592 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: sro:Sros_2255 ABC-type sugar transport system periplasmic component-like protein; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transporter periplasmic component-like protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein 1882279..1883592 Spirochaeta smaragdinae DSM 11293 9489847 YP_003803471.1 CDS Spirs_1751 NC_014364.1 1883658 1885112 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transporter; InterPro IPR004358:IPR003594:IPR005467; KEGG: pjd:Pjdr2_6107 histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 1883658..1885112 Spirochaeta smaragdinae DSM 11293 9489848 YP_003803472.1 CDS Spirs_1752 NC_014364.1 1885105 1885803 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: pjd:Pjdr2_6106 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 1885105..1885803 Spirochaeta smaragdinae DSM 11293 9489849 YP_003803473.1 CDS Spirs_1753 NC_014364.1 1885819 1886832 R COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR005886:IPR001509; KEGG: ttu:TERTU_3148 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase; UDP-glucose 4-epimerase complement(1885819..1886832) Spirochaeta smaragdinae DSM 11293 9489850 YP_003803474.1 CDS Spirs_1754 NC_014364.1 1886829 1887950 R InterPro IPR002575; KEGG: amu:Amuc_0030 hypothetical protein; PFAM: aminoglycoside phosphotransferase; SPTR: uncharacterized protein; PFAM: phosphotransferase enzyme family; aminoglycoside phosphotransferase complement(1886829..1887950) Spirochaeta smaragdinae DSM 11293 9489851 YP_003803475.1 CDS Spirs_1755 NC_014364.1 1887947 1888846 R KEGG: caa:Caka_1842 hypothetical protein; SPTR: uncharacterized protein; PFAM: nucleotidyl transferase; hypothetical protein complement(1887947..1888846) Spirochaeta smaragdinae DSM 11293 9489852 YP_003803476.1 CDS Spirs_1756 NC_014364.1 1888921 1889799 D COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterProIPR020449:IPR018771:IPR000005:IPR018062:IPR 018060; KEGG: csc:Csac_1509 helix-turn-helix domain-containing protein; PFAM: transcriptional regulator, histidine kinase sensor-like; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Predicted histidine kinase sensor domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 1888921..1889799 Spirochaeta smaragdinae DSM 11293 9489853 YP_003803477.1 CDS Spirs_1757 NC_014364.1 1889892 1891286 D InterPro IPR001440:IPR019734:IPR013026; KEGG: bsu:BSU22590 hypothetical protein; PFAM: hypothetical protein; SPTR: TPR repeat-containing protein ypiA; hypothetical protein 1889892..1891286 Spirochaeta smaragdinae DSM 11293 9489854 YP_003803478.1 CDS Spirs_1758 NC_014364.1 1891267 1894119 R COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR019775; KEGG: aoe:Clos_2611 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; acriflavin resistance protein complement(1891267..1894119) Spirochaeta smaragdinae DSM 11293 9489855 YP_003803479.1 CDS Spirs_1759 NC_014364.1 1894106 1897090 R COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR000731; KEGG: hor:Hore_05050 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; acriflavin resistance protein complement(1894106..1897090) Spirochaeta smaragdinae DSM 11293 9489856 YP_003803480.1 CDS Spirs_1760 NC_014364.1 1897087 1898505 R KEGG: lbl:LBL_0958 lipoprotein; SPTR: Conserved hypothetical lipoprotein; hypothetical protein complement(1897087..1898505) Spirochaeta smaragdinae DSM 11293 9489857 YP_003803481.1 CDS Spirs_1761 NC_014364.1 1898502 1899926 R KEGG: lbl:LBL_0959 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1898502..1899926) Spirochaeta smaragdinae DSM 11293 9489858 YP_003803482.1 CDS Spirs_1762 NC_014364.1 1899983 1901335 R COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143:IPR003997:IPR005479; KEGG: lbl:LBL_0963 membrane efflux protein; PFAM: secretion protein HlyD; SPTR: membrane efflux protein; TIGRFAM: efflux transporter RND family, MFP subunit; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit complement(1899983..1901335) Spirochaeta smaragdinae DSM 11293 9489859 YP_003803483.1 CDS Spirs_1763 NC_014364.1 1901332 1902726 R COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: lic:LIC10496 hypothetical protein; PFAM: outer membrane efflux protein; SPTR: uncharacterized protein; PFAM: Outer membrane efflux protein; outer membrane efflux protein complement(1901332..1902726) Spirochaeta smaragdinae DSM 11293 9489860 YP_003803484.1 CDS Spirs_1764 NC_014364.1 1902723 1903184 R KEGG: tte:TTE1035 methylesterase CheB/methylase CheR; SPTR: ABC superfamily ATP binding cassette transporter ABC protein; hypothetical protein complement(1902723..1903184) Spirochaeta smaragdinae DSM 11293 9489861 YP_003803485.1 CDS Spirs_1765 NC_014364.1 1903181 1903825 R COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001440:IPR019734:IPR013026; KEGG: rca:Rcas_0215 TPR repeat-containing protein; PFAM: hypothetical protein; SPTR: hypothetical protein; hypothetical protein complement(1903181..1903825) Spirochaeta smaragdinae DSM 11293 9489862 YP_003803486.1 CDS Spirs_1766 NC_014364.1 1904044 1913541 D KEGG: lif:LinJ14.1210 kinesin K39; SPTR: Kinesin K39; hypothetical protein 1904044..1913541 Spirochaeta smaragdinae DSM 11293 9489863 YP_003803487.1 CDS Spirs_1767 NC_014364.1 1913519 1914490 D KEGG: tde:TDE1705 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1913519..1914490 Spirochaeta smaragdinae DSM 11293 9489864 YP_003803488.1 CDS Spirs_1768 NC_014364.1 1914833 1915657 D KEGG: cbb:CLD_2659 internalin; SPTR: Leucine-rich repeat protein; hypothetical protein 1914833..1915657 Spirochaeta smaragdinae DSM 11293 9489865 YP_003803489.1 CDS Spirs_1769 NC_014364.1 1915700 1916656 D KEGG: tde:TDE1705 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1915700..1916656 Spirochaeta smaragdinae DSM 11293 9489866 YP_003803490.1 CDS Spirs_1770 NC_014364.1 1916799 1917002 D KEGG: bab:bbp447 preprotein translocase subunit SecY; hypothetical protein 1916799..1917002 Spirochaeta smaragdinae DSM 11293 9489867 YP_003803491.1 CDS Spirs_1771 NC_014364.1 1917348 1918346 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tnp:Tnap_1576 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 1917348..1918346 Spirochaeta smaragdinae DSM 11293 9489868 YP_003803492.1 CDS Spirs_1772 NC_014364.1 1918380 1919672 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: pjd:Pjdr2_4060 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein 1918380..1919672 Spirochaeta smaragdinae DSM 11293 9489869 YP_003803493.1 CDS Spirs_1773 NC_014364.1 1919748 1920617 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tle:Tlet_1579 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 1919748..1920617 Spirochaeta smaragdinae DSM 11293 9489870 YP_003803494.1 CDS Spirs_1774 NC_014364.1 1920614 1921423 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bcl:ABC0400 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1920614..1921423 Spirochaeta smaragdinae DSM 11293 9489871 YP_003803495.1 CDS Spirs_1775 NC_014364.1 1921428 1923446 D KEGG: bth:BT_2899 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1921428..1923446 Spirochaeta smaragdinae DSM 11293 9489872 YP_003803496.1 CDS Spirs_1776 NC_014364.1 1923448 1924200 D InterPro IPR005135; KEGG: noc:Noc_0998 endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase; SPTR: endonuclease/exonuclease/phosphatase; PFAM: endonuclease/exonuclease/phosphatase family; endonuclease/exonuclease/phosphatase 1923448..1924200 Spirochaeta smaragdinae DSM 11293 9489873 YP_003803497.1 CDS Spirs_1777 NC_014364.1 1924291 1925733 R COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR020471:IPR001395; KEGG: str:Sterm_3498 2,5-didehydrogluconate reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(1924291..1925733) Spirochaeta smaragdinae DSM 11293 9489874 YP_003803498.1 CDS Spirs_1778 NC_014364.1 1925753 1926925 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670; KEGG: dsy:DSY2755 hypothetical protein; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(1925753..1926925) Spirochaeta smaragdinae DSM 11293 9489875 YP_003803499.1 CDS Spirs_1779 NC_014364.1 1927082 1927543 D COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: eel:EUBELI_00178 MerR family transcriptional regulator, mercuric resistance operon regulatory protein; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: uncharacterized protein; PFAM: MerR family regulatory protein; MerR family transcriptional regulator 1927082..1927543 Spirochaeta smaragdinae DSM 11293 9489876 YP_003803500.1 CDS Spirs_1780 NC_014364.1 1927881 1928462 R KEGG: swo:Swol_1999 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1927881..1928462) Spirochaeta smaragdinae DSM 11293 9489877 YP_003803501.1 CDS Spirs_1781 NC_014364.1 1928618 1929289 D KEGG: ote:Oter_2659 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1928618..1929289 Spirochaeta smaragdinae DSM 11293 9489878 YP_003803502.1 CDS Spirs_1782 NC_014364.1 1929448 1930050 D KEGG: ote:Oter_2660 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1929448..1930050 Spirochaeta smaragdinae DSM 11293 9489879 YP_003803503.1 CDS Spirs_1783 NC_014364.1 1930183 1931331 D COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; KEGG: sro:Sros_5559 ABC transporter periplasmic substrate-binding protein; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; ABC transporter periplasmic substrate-binding protein 1930183..1931331 Spirochaeta smaragdinae DSM 11293 9489880 YP_003803504.1 CDS Spirs_1784 NC_014364.1 1931401 1933194 D COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: cpy:Cphy_2143 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1931401..1933194 Spirochaeta smaragdinae DSM 11293 9489881 YP_003803505.1 CDS Spirs_1785 NC_014364.1 1933194 1934306 D COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR003439:IPR013611:IPR017871:IPR003593; KEGG: tpe:Tpen_1165 ABC transporter; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; TOBE domain; ABC transporter 1933194..1934306 Spirochaeta smaragdinae DSM 11293 9489882 YP_003803506.1 CDS Spirs_1786 NC_014364.1 1934350 1935078 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cbi:CLJ_B2758 phosphate regulon DNA-binding response regulator; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; SPTR: phosphate regulon DNA-binding response regulator; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 1934350..1935078 Spirochaeta smaragdinae DSM 11293 9489883 YP_003803507.1 CDS Spirs_1787 NC_014364.1 1935075 1936832 D COGs: COG5002 Signal transduction histidine kinase; InterProIPR000014:IPR004358:IPR013767:IPR003661:IPR 003594:IPR005467:IPR003660; KEGG: amt:Amet_3086 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; multi-sensor signal transduction histidine kinase 1935075..1936832 Spirochaeta smaragdinae DSM 11293 9489884 YP_003803508.1 CDS Spirs_1788 NC_014364.1 1936842 1938239 D COGs: COG1109 phosphomannomutase; InterProIPR005841:IPR005844:IPR005845:IPR005846:IPR 005843:IPR016066; KEGG: acr:Acry_1021 phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase; SPTR: phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 1936842..1938239 Spirochaeta smaragdinae DSM 11293 9489885 YP_003803509.1 CDS Spirs_1789 NC_014364.1 1938313 1939161 D COGs: COG4786 flagellar basal body rod protein; InterPro IPR020013:IPR012836:IPR001444:IPR010930; KEGG: bre:BRE_783 flagellar hook-basal body complex protein; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: flagellar hook-basal body complex protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgF; fagellar hook-basal body proteins; flagellar basal-body rod protein FlgF 1938313..1939161 Spirochaeta smaragdinae DSM 11293 9489886 YP_003803510.1 CDS Spirs_1790 NC_014364.1 1939176 1939970 D COGs: COG4786 flagellar basal body rod protein; InterProIPR020013:IPR012834:IPR001444:IPR010930:IPR 019776; KEGG: tde:TDE1007 flagellar basal body rod protein FlgG; PFAM: protein of unknown function DUF1078 domain protein; flagellar basal body rod protein; SPTR: flagellar basal-body rod protein FlgG; TIGRFAM: flagellar basal-body rod protein FlgG; fagellar hook-basal body protein; PFAM: Domain of unknown function (DUF1078); Flagella basal body rod protein; TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria; flagellar basal-body rod protein FlgG 1939176..1939970 Spirochaeta smaragdinae DSM 11293 9489887 YP_003803511.1 CDS Spirs_1791 NC_014364.1 1939983 1940816 D KEGG: sna:Snas_3135 GTPase EngC; SPTR: GTPase EngC; hypothetical protein 1939983..1940816 Spirochaeta smaragdinae DSM 11293 9489888 YP_003803512.1 CDS Spirs_1792 NC_014364.1 1940813 1941868 D COGs: COG1706 flagellar basal-body P-ring protein; InterPro IPR001782; KEGG: rce:RC1_1393 flagellar P-ring protein FlgI; PFAM: flagellar P-ring protein; SPTR: flagellar P-ring protein; PFAM: flagellar P-ring protein; flagellar P-ring protein 1940813..1941868 Spirochaeta smaragdinae DSM 11293 9489889 YP_003803513.1 CDS Spirs_1793 NC_014364.1 1941881 1942198 D InterPro IPR019301; KEGG: bhy:BHWA1_02584 hypothetical protein; PFAM: flagellar protein FlgJ-like; SPTR: uncharacterized protein; PFAM: Rod binding protein; flagellar protein FlgJ 1941881..1942198 Spirochaeta smaragdinae DSM 11293 9489890 YP_003803514.1 CDS Spirs_1794 NC_014364.1 1942338 1943183 D COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR014284:IPR000943:IPR009042:IPR007627:IPR 007624:IPR007630:IPR005479; KEGG: aco:Amico_1627 RNA polymerase, sigma 70 subunit, RpoD subfamily; PFAM: sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 region 3 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RpoD subfamily RNA polymerase sigma-70 subunit 1942338..1943183 Spirochaeta smaragdinae DSM 11293 9489891 YP_003803515.1 CDS Spirs_1795 NC_014364.1 1943215 1944159 D COGs: COG2861 conserved hypothetical protein; InterPro IPR006837; KEGG: tde:TDE2503 hypothetical protein; PFAM: protein of unknown function DUF610 YibQ; SPTR: Divergent polysaccharide deacetylase family protein; PFAM: Divergent polysaccharide deacetylase; hypothetical protein 1943215..1944159 Spirochaeta smaragdinae DSM 11293 9489892 YP_003803516.1 CDS Spirs_1796 NC_014364.1 1944162 1945175 D COGs: COG0533 metal-dependent protease with chaperone activity; InterPro IPR017861:IPR000905:IPR017860; KEGG: tde:TDE2504 DNA-binding/iron metalloprotein/AP endonuclease; PFAM: peptidase M22 glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: O-sialoglycoprotein endopeptidase; TIGRFAM: metalloendopeptidase, glycoprotease family; PFAM: glycoprotease family; TIGRFAM: metalloendopeptidase, , glycoprotease family; metalloendopeptidase, glycoprotease family 1944162..1945175 Spirochaeta smaragdinae DSM 11293 9489893 YP_003803517.1 CDS Spirs_1797 NC_014364.1 1945185 1946144 R COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: bbz:BbuZS7_0750 ATP-binding protein; PFAM: cobyrinic acid ac-diamide synthase; SPTR: ATP-binding protein; manually curated; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase complement(1945185..1946144) Spirochaeta smaragdinae DSM 11293 9489894 YP_003803518.1 CDS Spirs_1798 NC_014364.1 1946239 1946772 D COGs: COG0503 adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836:IPR005764; KEGG: tde:TDE1684 adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; SPTR: adenine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: adenine phosphoribosyltransferase; phosphoribosyltransferase 1946239..1946772 Spirochaeta smaragdinae DSM 11293 9489895 YP_003803519.1 CDS Spirs_1799 NC_014364.1 1947045 1948784 D KEGG: tpp:TPASS_0110 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1947045..1948784 Spirochaeta smaragdinae DSM 11293 9489898 YP_003803520.1 CDS Spirs_1800 NC_014364.1 1948765 1949487 D COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: wsu:WS0972 hypothetical protein; PFAM: protein of unknown function DUF152; SPTR: BH2551 PROTEIN; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: conserved hypothetical protein TIGR00726; hypothetical protein 1948765..1949487 Spirochaeta smaragdinae DSM 11293 9489899 YP_003803521.1 CDS Spirs_1801 NC_014364.1 1949542 1951323 D COGs: COG0018 Arginyl-tRNA synthetase; InterProIPR001278:IPR015945:IPR005148:IPR008909:IPR 001412; KEGG: tde:TDE0971 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; arginyl tRNA synthetase domain protein; DALR anticodon binding domain protein; PRIAM: Arginine--tRNA ligase; SPTR: Arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase; arginyl-tRNA synthetase 1949542..1951323 Spirochaeta smaragdinae DSM 11293 9489900 YP_003803522.1 CDS Spirs_1802 NC_014364.1 1951395 1951709 D COGs: COG0261 ribosomal protein L21; InterPro IPR001787:IPR018258; KEGG: tde:TDE1751 50S ribosomal protein L21; PFAM: ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: ribosomal protein L21; PFAM: ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21; 50S ribosomal protein L21 1951395..1951709 Spirochaeta smaragdinae DSM 11293 9489901 YP_003803523.1 CDS Spirs_1803 NC_014364.1 1951725 1952063 D InterPro IPR007422; KEGG: hmo:HM1_2710 ribosomal protein, PFAM: protein of unknown function DUF464; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF464); hypothetical protein 1951725..1952063 Spirochaeta smaragdinae DSM 11293 9489902 YP_003803524.1 CDS Spirs_1804 NC_014364.1 1952070 1952327 D COGs: COG0211 ribosomal protein L27; InterPro IPR001684:IPR018261; KEGG: mab:MAB_1611 50S ribosomal protein L27; PFAM: ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: ribosomal protein L27; PFAM: ribosomal L27 protein; TIGRFAM: ribosomal protein L27; 50S ribosomal protein L27 1952070..1952327 Spirochaeta smaragdinae DSM 11293 9489903 YP_003803525.1 CDS Spirs_1805 NC_014364.1 1952338 1953342 D COGs: COG0536 GTPase; InterPro IPR014100:IPR006073:IPR006169:IPR002917; KEGG: tde:TDE1748 GTPase ObgE; PFAM: GTP1/OBG sub domain protein; GTP-binding protein HSR1-related; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; PFAM: GTPase of unknown function; GTP1/OBG; TIGRFAM: Obg family GTPase CgtA; small GTP-binding protein domain; GTP-binding protein Obg/CgtA 1952338..1953342 Spirochaeta smaragdinae DSM 11293 9489904 YP_003803526.1 CDS Spirs_1806 NC_014364.1 1953339 1953905 D COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; InterPro IPR004821:IPR005248:IPR004820; KEGG: tpp:TPASS_0741 hypothetical protein; PFAM: cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Nicotinate nucleotide adenylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain; nicotinate (nicotinamide) nucleotide adenylyltransferase 1953339..1953905 Spirochaeta smaragdinae DSM 11293 9489905 YP_003803527.1 CDS Spirs_1807 NC_014364.1 1953902 1954513 D COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR006675:IPR006674:IPR003607; KEGG: nth:Nther_0534 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: Nicotinate-nucleotide adenylyltransferase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: conserved hypothetical protein TIGR00488; uncharacterized domain HDIG; metal dependent phosphohydrolase 1953902..1954513 Spirochaeta smaragdinae DSM 11293 9489906 YP_003803528.1 CDS Spirs_1808 NC_014364.1 1954485 1955690 D COGs: COG1316 transcriptional regulator; KEGG: tpp:TPASS_0739 hypothetical protein; SPTR: uncharacterized protein; PFAM: cell envelope-related transcriptional attenuator domain; hypothetical protein 1954485..1955690 Spirochaeta smaragdinae DSM 11293 9489907 YP_003803529.1 CDS Spirs_1809 NC_014364.1 1955692 1956030 D COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: dhd:Dhaf_4329 iojap-like protein; PFAM: Iojap-related protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-related protein; Iojap-like protein 1955692..1956030 Spirochaeta smaragdinae DSM 11293 9489908 YP_003803530.1 CDS Spirs_1810 NC_014364.1 1956120 1956380 R KEGG: tde:TDE2071 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(1956120..1956380) Spirochaeta smaragdinae DSM 11293 9489909 YP_003803531.1 CDS Spirs_1811 NC_014364.1 1956506 1956997 R InterPro IPR007597; KEGG: nth:Nther_0634 chemotaxis protein CheC; PFAM: chemotaxis protein CheC; SPTR: chemotaxis protein CheC; PFAM: CheC-like family; chemotaxis protein CheC complement(1956506..1956997) Spirochaeta smaragdinae DSM 11293 9489910 YP_003803532.1 CDS Spirs_1812 NC_014364.1 1957047 1957979 D COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; InterPro IPR004424:IPR006204:IPR013750; KEGG: tye:THEYE_A1457 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase domain protein; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR: 4-(Cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; 4-diphosphocytidyl-2C-methyl-D-erythritol kinase 1957047..1957979 Spirochaeta smaragdinae DSM 11293 9489911 YP_003803533.1 CDS Spirs_1813 NC_014364.1 1958011 1958319 D COGs: COG2088 Uncharacterized protein involved in the regulation of septum location; InterPro IPR007170; KEGG: tpd:Teth39_0160 regulatory protein SpoVG; PFAM: SpoVG family protein; SPTR: uncharacterized protein; PFAM: SpoVG; SpoVG family protein 1958011..1958319 Spirochaeta smaragdinae DSM 11293 9489912 YP_003803534.1 CDS Spirs_1814 NC_014364.1 1958519 1959148 D COGs: COG1825 ribosomal protein L25 (general stress protein Ctc); InterPro IPR001021:IPR020055; KEGG: tde:TDE1340 50S ribosomal protein L25/general stress protein Ctc; PFAM: ribosomal protein L25-like; SPTR: 50S ribosomal protein L25; TIGRFAM: ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5; PFAM: ribosomal L25p family; TIGRFAM: ribosomal protein L25, Ctc-form; ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 1958519..1959148 Spirochaeta smaragdinae DSM 11293 9489914 YP_003803535.1 CDS Spirs_1815 NC_014364.1 1959158 1959751 D COGs: COG0193 peptidyl-tRNA hydrolase; InterPro IPR001328:IPR018171; KEGG: gyc:GYMC61_0046 peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; PFAM: peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase; peptidyl-tRNA hydrolase 1959158..1959751 Spirochaeta smaragdinae DSM 11293 9489915 YP_003803536.1 CDS Spirs_1816 NC_014364.1 1959735 1961084 D COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR012795:IPR012796:IPR011063; KEGG: tde:TDE1341 hypothetical protein; PFAM: PP-loop domain protein; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: TilS substrate C-terminal domain; PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain; tRNA(Ile)-lysidine synthetase 1959735..1961084 Spirochaeta smaragdinae DSM 11293 9489916 YP_003803537.1 CDS Spirs_1817 NC_014364.1 1961056 1962999 D COGs: COG0465 ATP-dependent Zn protease; InterProIPR005936:IPR011546:IPR003959:IPR000642:IPR 003960:IPR003593; KEGG: bre:BRE_798 cell division protein; PFAM: peptidase M41; ATPase AAA; peptidase M41 FtsH extracellular; PRIAM: microtubule-severing ATPase; SMART: ATPase AAA; SPTR: cell division protein; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH extracellular; peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; ATP-dependent metalloprotease FtsH 1961056..1962999 Spirochaeta smaragdinae DSM 11293 9489917 YP_003803538.1 CDS Spirs_1818 NC_014364.1 1963048 1964754 D InterPro IPR013026; KEGG: tde:TDE1342 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1963048..1964754 Spirochaeta smaragdinae DSM 11293 9489918 YP_003803539.1 CDS Spirs_1819 NC_014364.1 1964756 1966570 D COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001940:IPR001254:IPR001478; KEGG: tpp:TPASS_0546 periplasmic serine protease; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SMART: PDZ/DHR/GLGF domain protein; SPTR: Trypsin domain/PDZ domain protein; PFAM: Trypsin; peptidase S1 and S6 chymotrypsin/Hap 1964756..1966570 Spirochaeta smaragdinae DSM 11293 9489919 YP_003803540.1 CDS Spirs_1820 NC_014364.1 1966634 1966963 D InterPro IPR002645; KEGG: dde:Dde_1700 chemotaxis protein CheA; SPTR: anti-sigma-factor antagonist; chemotaxis protein CheA 1966634..1966963 Spirochaeta smaragdinae DSM 11293 9489920 YP_003803541.1 CDS Spirs_1821 NC_014364.1 1966984 1969119 D COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR004358:IPR008207:IPR004105:IPR003594:IPR 002545:IPR005467; KEGG: gsu:GSU1290 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: Hpt domain protein; ATP-binding region ATPase domain protein; CheW domain protein; SPTR: Chemotaxis protein CheA; PFAM: CheW-like domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; chemotaxis protein CheA 1966984..1969119 Spirochaeta smaragdinae DSM 11293 9489921 YP_003803542.1 CDS Spirs_1822 NC_014364.1 1969126 1969974 D COGs: COG1352 methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: gbm:Gbem_1595 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase CheR-type; PRIAM: protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; CheR-type MCP methyltransferase 1969126..1969974 Spirochaeta smaragdinae DSM 11293 9489922 YP_003803543.1 CDS Spirs_1823 NC_014364.1 1969983 1971065 D COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR008248:IPR001789:IPR000673; KEGG: gsu:GSU1145 protein-glutamate methylesterase; PFAM: CheB methylesterase; response regulator receiver; PRIAM: protein-glutamate methylesterase; SMART: response regulator receiver; SPTR: Chemotaxis response regulator protein-glutamate methylesterase of group 2 operon; PFAM: CheB methylesterase; Response regulator receiver domain; response regulator receiver modulated CheB methylesterase 1969983..1971065 Spirochaeta smaragdinae DSM 11293 9489923 YP_003803544.1 CDS Spirs_1824 NC_014364.1 1971086 1972489 D COGs: COG4585 Signal transduction histidine kinase; InterProIPR000014:IPR001789:IPR013767:IPR011712:IPR 003594:IPR019775:IPR005467:IPR000700; KEGG: sru:SRU_0678 sensor protein FixL; PFAM: response regulator receiver; PAS fold domain protein; histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: response regulator receiver; PAS domain containing protein; ATP-binding region ATPase domain protein; SPTR: Sensor protein fixL; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor signal transduction histidine kinase 1971086..1972489 Spirochaeta smaragdinae DSM 11293 9489924 YP_003803545.1 CDS Spirs_1825 NC_014364.1 1972486 1973136 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: ote:Oter_0043 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 1972486..1973136 Spirochaeta smaragdinae DSM 11293 9489925 YP_003803546.1 CDS Spirs_1826 NC_014364.1 1973141 1974568 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR001789:IPR003661:IPR003594:IPR 005467; KEGG: dvm:DvMF_2677 response regulator receiver sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; response regulator receiver sensor signal transduction histidine kinase 1973141..1974568 Spirochaeta smaragdinae DSM 11293 9489926 YP_003803547.1 CDS Spirs_1827 NC_014364.1 1974585 1976477 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR004358:IPR001789:IPR013767:IPR 003661:IPR003594:IPR005467:IPR000700; KEGG: sfu:Sfum_3112 PAS/PAC sensor protein; PFAM: ATP-binding region ATPase domain protein; response regulator receiver; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor hybrid histidine kinase 1974585..1976477 Spirochaeta smaragdinae DSM 11293 9489927 YP_003803548.1 CDS Spirs_1828 NC_014364.1 1976528 1978336 D COGs: COG0481 membrane GTPase LepA; InterProIPR005225:IPR006297:IPR000795:IPR004161:IPR 000640:IPR013842; KEGG: tde:TDE1893 GTP-binding protein LepA; PFAM: GTP-binding protein LepA domain protein; protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; SPTR: GTP-binding protein lepA; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; GTP-binding protein LepA C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain; GTP-binding protein LepA 1976528..1978336 Spirochaeta smaragdinae DSM 11293 9489928 YP_003803549.1 CDS Spirs_1829 NC_014364.1 1978317 1979942 R COGs: COG2604 conserved hypothetical protein; InterPro IPR002826:IPR018271; KEGG: tde:TDE2525 hypothetical protein; PFAM: protein of unknown function DUF115; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF115; hypothetical protein complement(1978317..1979942) Spirochaeta smaragdinae DSM 11293 9489929 YP_003803550.1 CDS Spirs_1830 NC_014364.1 1979935 1981470 R InterPro IPR000297; KEGG: tde:TDE2526 hypothetical protein; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: uncharacterized protein; PFAM: PPIC-type PPIASE domain; PpiC-type peptidyl-prolyl cis-trans isomerase complement(1979935..1981470) Spirochaeta smaragdinae DSM 11293 9489930 YP_003803551.1 CDS Spirs_1831 NC_014364.1 1981585 1982385 D KEGG: scl:sce0311 DnaJ domain-containing protein; SPTR: uncharacterized protein; hypothetical protein 1981585..1982385 Spirochaeta smaragdinae DSM 11293 9489931 YP_003803552.1 CDS Spirs_1832 NC_014364.1 1982400 1983083 R KEGG: ptm:GSPATT00027845001 hypothetical protein; SPTR: TonB-dependent receptor; hypothetical protein complement(1982400..1983083) Spirochaeta smaragdinae DSM 11293 9489932 YP_003803553.1 CDS Spirs_1833 NC_014364.1 1983174 1984322 D KEGG: emi:Emin_0187 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 1983174..1984322 Spirochaeta smaragdinae DSM 11293 9489933 YP_003803554.1 CDS Spirs_1834 NC_014364.1 1984440 1986551 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dma:DMR_41450 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 1984440..1986551 Spirochaeta smaragdinae DSM 11293 9489934 YP_003803555.1 CDS Spirs_1835 NC_014364.1 1986560 1987618 R COGs: COG0863 DNA modification methylase; InterPro IPR001091:IPR017985:IPR019825:IPR002941; KEGG: dal:Dalk_3764 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SPTR: DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase; DNA methylase N-4/N-6 domain-containing protein complement(1986560..1987618) Spirochaeta smaragdinae DSM 11293 9489935 YP_003803556.1 CDS Spirs_1836 NC_014364.1 1987633 1988481 R KEGG: mba:Mbar_A3538 hypothetical protein; SPTR: uncharacterized protein; PFAM: histidine kinase; signal transduction histidine kinase complement(1987633..1988481) Spirochaeta smaragdinae DSM 11293 9489936 YP_003803557.1 CDS Spirs_1837 NC_014364.1 1988670 1989797 R InterPro IPR000792:IPR000014:IPR013767; KEGG: sat:SYN_00715 sensory domain-containing/LuxR family regulatory protein; PFAM: regulatory protein LuxR; PAS fold domain protein; SMART: regulatory protein LuxR; PAS domain containing protein; SPTR: sensory domain linked to a LuxR regulatory protein; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box; LuxR family transcriptional regulator complement(1988670..1989797) Spirochaeta smaragdinae DSM 11293 9489937 YP_003803558.1 CDS Spirs_1838 NC_014364.1 1990042 1991130 R COGs: COG1609 transcriptional regulators; InterPro IPR000524:IPR001761; KEGG: pjd:Pjdr2_0522 transcriptional regulator, GntR family with LacI sensor; PFAM: regulatory protein GntR HTH; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; family; GntR family transcriptional regulator complement(1990042..1991130) Spirochaeta smaragdinae DSM 11293 9489938 YP_003803559.1 CDS Spirs_1839 NC_014364.1 1991383 1992369 D COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; InterPro IPR005119; KEGG: bhy:BHWA1_00868 periplasmic-iron-binding protein BitB; PFAM: LysR substrate-binding; SPTR: Periplasmic-iron-binding protein BitB; PFAM: Bacterial extracellular solute-binding protein; LysR family transcriptional regulator 1991383..1992369 Spirochaeta smaragdinae DSM 11293 9489939 YP_003803560.1 CDS Spirs_1840 NC_014364.1 1992431 1994473 D COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: sth:STH1155 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 1992431..1994473 Spirochaeta smaragdinae DSM 11293 9489940 YP_003803561.1 CDS Spirs_1841 NC_014364.1 1994460 1995512 D COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR017871:IPR003439; KEGG: sfu:Sfum_3496 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 1994460..1995512 Spirochaeta smaragdinae DSM 11293 9489941 YP_003803562.1 CDS Spirs_1842 NC_014364.1 1995493 1997787 D COGs: COG3408 glycogen debranching protein; KEGG: cma:Cmaq_1011 glycoside hydrolase family protein; SPTR: glycoside hydrolase family 37; PFAM: Trehalase; glycogen debranching protein 1995493..1997787 Spirochaeta smaragdinae DSM 11293 9489942 YP_003803563.1 CDS Spirs_1843 NC_014364.1 1997923 1998933 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cdf:CD0776 LacI family transcriptional regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI-family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 1997923..1998933 Spirochaeta smaragdinae DSM 11293 9489943 YP_003803564.1 CDS Spirs_1844 NC_014364.1 1999180 2000610 D InterPro IPR000560; KEGG: cms:CMS_2887 sortase-sorted surface-anchored protein; PFAM: histidine acid phosphatase; SPTR: uncharacterized protein; PFAM: histidine acid phosphatase; histidine acid phosphatase 1999180..2000610 Spirochaeta smaragdinae DSM 11293 9489944 YP_003803565.1 CDS Spirs_1845 NC_014364.1 2000764 2001825 D COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; InterPro IPR006059; KEGG: sth:STH3219 iron ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Iron(III) dicitrate transport ATP-binding protein FecE; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 2000764..2001825 Spirochaeta smaragdinae DSM 11293 9489945 YP_003803566.1 CDS Spirs_1846 NC_014364.1 2001878 2003563 D COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: sth:STH3218 ABC transporter permease protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 2001878..2003563 Spirochaeta smaragdinae DSM 11293 9489946 YP_003803567.1 CDS Spirs_1847 NC_014364.1 2003568 2004707 D COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR017871:IPR003439:IPR013611; KEGG: ctc:CTC00276 iron(III)-transport ATP-binding protein SfuC; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: Iron(III)-transport ATP-binding protein sfuC; PFAM: ABC transporter; TOBE domain; ABC transporter 2003568..2004707 Spirochaeta smaragdinae DSM 11293 9489947 YP_003803568.1 CDS Spirs_1848 NC_014364.1 2004700 2005506 D COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: dsy:DSY4852 hypothetical protein; PFAM: haloacid dehalogenase type 3; SPTR: Cof-like hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; Cof-like hydrolase 2004700..2005506 Spirochaeta smaragdinae DSM 11293 9489948 YP_003803569.1 CDS Spirs_1849 NC_014364.1 2005503 2006396 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: kol:Kole_0981 hypothetical protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 2005503..2006396 Spirochaeta smaragdinae DSM 11293 9489949 YP_003803570.1 CDS Spirs_1850 NC_014364.1 2006469 2007473 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: hor:Hore_04570 transcriptional regulator, LacI family; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 2006469..2007473 Spirochaeta smaragdinae DSM 11293 9489950 YP_003803571.1 CDS Spirs_1851 NC_014364.1 2007522 2008217 D KEGG: hor:Hore_20030 PHP domain protein; SPTR: PHP domain protein; PHP domain-containing protein 2007522..2008217 Spirochaeta smaragdinae DSM 11293 9489951 YP_003803572.1 CDS Spirs_1852 NC_014364.1 2008208 2008969 D COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006439; KEGG: mfe:Mefer_0183 HAD superfamily (subfamily IA) hydrolase, TIGR02253; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: HAD superfamily (Subfamily IA) hydrolase, TIGR02253; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD-superfamily hydrolase 2008208..2008969 Spirochaeta smaragdinae DSM 11293 9489952 YP_003803573.1 CDS Spirs_1853 NC_014364.1 2009000 2010835 D COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR001917:IPR000515; KEGG: pjd:Pjdr2_0285 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component; binding-protein-dependent transporters inner membrane component 2009000..2010835 Spirochaeta smaragdinae DSM 11293 9489953 YP_003803574.1 CDS Spirs_1854 NC_014364.1 2010837 2011976 D COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR017871:IPR003439:IPR013611; KEGG: pjd:Pjdr2_0286 ABC transporter related; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; TOBE domain; ABC transporter 2010837..2011976 Spirochaeta smaragdinae DSM 11293 9489954 YP_003803575.1 CDS Spirs_1855 NC_014364.1 2012040 2013218 D COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; KEGG: pjd:Pjdr2_0284 extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 2012040..2013218 Spirochaeta smaragdinae DSM 11293 9489955 YP_003803576.1 CDS Spirs_1856 NC_014364.1 2013285 2014157 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: tma:TM0415 hypothetical protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 2013285..2014157 Spirochaeta smaragdinae DSM 11293 9489956 YP_003803577.1 CDS Spirs_1857 NC_014364.1 2014629 2015645 D COGs: COG1609 transcriptional regulators; InterPro IPR000524; KEGG: tnp:Tnap_0905 GntR family transcriptional regulator with LacI sensor; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator, GntR family with LacI sensor; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator 2014629..2015645 Spirochaeta smaragdinae DSM 11293 9489957 YP_003803578.1 CDS Spirs_1858 NC_014364.1 2015633 2016550 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sli:Slin_2646 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein complement(2015633..2016550) Spirochaeta smaragdinae DSM 11293 9489958 YP_003803579.1 CDS Spirs_1859 NC_014364.1 2016575 2017222 R COGs: COG0176 transaldolase; InterPro IPR018225; KEGG: bcx:BCA_3466 transaldolase; SPTR: uncharacterized protein; PFAM: transaldolase; transaldolase complement(2016575..2017222) Spirochaeta smaragdinae DSM 11293 9489959 YP_003803580.1 CDS Spirs_1860 NC_014364.1 2017235 2017990 R COGs: COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; KEGG: rca:Rcas_2756 hypothetical protein; SPTR: Uncharacterized protein containing SIS (Sugar isomerase) phosphosugar binding domain-like protein; hypothetical protein complement(2017235..2017990) Spirochaeta smaragdinae DSM 11293 9489960 YP_003803581.1 CDS Spirs_1861 NC_014364.1 2018166 2019344 D KEGG: dsy:DSY4756 hypothetical protein; SPTR: uncharacterized protein; PFAM: uroporphyrinogen decarboxylase (URO-D); hypothetical protein 2018166..2019344 Spirochaeta smaragdinae DSM 11293 9489961 YP_003803582.1 CDS Spirs_1862 NC_014364.1 2019420 2020445 D COGs: COG4213 ABC-type xylose transporter periplasmic component; InterPro IPR001761; KEGG: amt:Amet_2814 monosaccharide-transporting ATPase; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: sugar ATP transporter ATPase; PFAM: family; TIGRFAM: D-xylose ABC transporter substrate-binding protein; periplasmic binding protein/LacI transcriptional regulator 2019420..2020445 Spirochaeta smaragdinae DSM 11293 9489962 YP_003803583.1 CDS Spirs_1863 NC_014364.1 2020509 2022071 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR017871:IPR003439; KEGG: tit:Thit_0247 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 2020509..2022071 Spirochaeta smaragdinae DSM 11293 9489963 YP_003803584.1 CDS Spirs_1864 NC_014364.1 2022058 2023239 D COGs: COG4214 ABC-type xylose transporter permease component; InterPro IPR001851; KEGG: amt:Amet_2812 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 2022058..2023239 Spirochaeta smaragdinae DSM 11293 9489964 YP_003803585.1 CDS Spirs_1865 NC_014364.1 2023379 2024512 R COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR017896:IPR001450; KEGG: cth:Cthe_1546 4Fe-4S ferredoxin iron-sulfur binding; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding; PFAM: Domain of unknown function (DUF362); 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(2023379..2024512) Spirochaeta smaragdinae DSM 11293 9489965 YP_003803586.1 CDS Spirs_1866 NC_014364.1 2025041 2025274 D InterPro IPR006628; KEGG: tde:TDE0865 hypothetical protein; SMART: PUR-alpha/beta/gamma DNA/RNA-binding; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3276); PUR-alpha/beta/gamma DNA/RNA-binding protein 2025041..2025274 Spirochaeta smaragdinae DSM 11293 9489967 YP_003803587.1 CDS Spirs_1867 NC_014364.1 2025255 2025827 R COGs: COG0164 ribonuclease HII; InterPro IPR001352; KEGG: tde:TDE1547 ribonuclease HII; PFAM: ribonuclease HII/HIII; PRIAM: ribonuclease H; SPTR: ribonuclease HII; PFAM: ribonuclease HII; ribonuclease H complement(2025255..2025827) Spirochaeta smaragdinae DSM 11293 9489968 YP_003803588.1 CDS Spirs_1868 NC_014364.1 2025917 2028742 D COGs: COG1196 chromosome segregation ATPase; InterPro IPR003395:IPR011890; KEGG: tde:TDE1496 chromosome partition protein SmC, PFAM: SMC domain protein; SPTR: chromosome segregation protein SMC; TIGRFAM: chromosome segregation protein SMC; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type; chromosome segregation protein SMC 2025917..2028742 Spirochaeta smaragdinae DSM 11293 9489969 YP_003803589.1 CDS Spirs_1869 NC_014364.1 2028714 2029097 D KEGG: isc:IscW_ISCW000348 secreted mucin MUC17, SPTR: uncharacterized protein; hypothetical protein 2028714..2029097 Spirochaeta smaragdinae DSM 11293 9489970 YP_003803590.1 CDS Spirs_1870 NC_014364.1 2029094 2030500 D KEGG: tpp:TPASS_0369 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2029094..2030500 Spirochaeta smaragdinae DSM 11293 9489971 YP_003803591.1 CDS Spirs_1871 NC_014364.1 2030562 2031893 D COGs: COG0541 Signal recognition particle GTPase; InterProIPR003593:IPR000897:IPR013822:IPR004125:IPR 004780; KEGG: tde:TDE2089 signal recognition particle protein; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; Signal peptide binding (SRP54) M- domain protein; SMART: ATPase AAA; SPTR: Signal recognition particle protein; TIGRFAM: signal recognition particle protein; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle protein; signal recognition particle protein 2030562..2031893 Spirochaeta smaragdinae DSM 11293 9489972 YP_003803592.1 CDS Spirs_1872 NC_014364.1 2031922 2032176 D COGs: COG0228 ribosomal protein S16; InterPro IPR000307; KEGG: tde:TDE0881 ribosomal protein S16; PFAM: ribosomal protein S16; SPTR: ribosomal protein S16; TIGRFAM: ribosomal protein S16; PFAM: ribosomal protein S16; TIGRFAM: ribosomal protein S16; 30S ribosomal protein S16 2031922..2032176 Spirochaeta smaragdinae DSM 11293 9489973 YP_003803593.1 CDS Spirs_1873 NC_014364.1 2032206 2032439 D COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR020627; KEGG: bhy:BHWA1_02049 R-binding protein (contains KH domain); SPTR: R-binding protein (Contains KH domain); R-binding protein (contains KH domain) 2032206..2032439 Spirochaeta smaragdinae DSM 11293 9489974 YP_003803594.1 CDS Spirs_1874 NC_014364.1 2032439 2032936 D COGs: COG0806 RimM protein required for 16S rRNA processing; InterPro IPR011961:IPR018120:IPR002676:IPR007903; KEGG: tde:TDE0883 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel domain protein; SPTR: 16S rRNA processing protein RimM; TIGRFAM: 16S rRNA processing protein RimM; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM; 16S rRNA processing protein RimM 2032439..2032936 Spirochaeta smaragdinae DSM 11293 9489975 YP_003803595.1 CDS Spirs_1875 NC_014364.1 2032933 2033631 D COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; InterPro IPR002649:IPR016009; KEGG: tde:TDE0884 tRNA (guanine-N(1)-)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase; tRNA (guanine-N1)-methyltransferase 2032933..2033631 Spirochaeta smaragdinae DSM 11293 9489976 YP_003803596.1 CDS Spirs_1876 NC_014364.1 2033657 2034034 D COGs: COG0335 ribosomal protein L19; InterPro IPR001857:IPR018257; KEGG: tde:TDE0885 50S ribosomal protein L19; PFAM: ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: ribosomal protein L19; PFAM: ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type; 50S ribosomal protein L19 2033657..2034034 Spirochaeta smaragdinae DSM 11293 9489977 YP_003803597.1 CDS Spirs_1877 NC_014364.1 2034098 2035048 D KEGG: lxx:Lxx13710 serine protease; SPTR: serine protease; hypothetical protein 2034098..2035048 Spirochaeta smaragdinae DSM 11293 9489978 YP_003803598.1 CDS Spirs_1878 NC_014364.1 2035057 2035311 D COGs: COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; InterPro IPR006135; KEGG: cjd:JJD26997_0996 FlhB domain-containing protein; PFAM: type III secretion exporter; SPTR: FlhB domain protein; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flhB C-terminus-related protein; type III secretion exporter 2035057..2035311 Spirochaeta smaragdinae DSM 11293 9489979 YP_003803599.1 CDS Spirs_1879 NC_014364.1 2035308 2036432 D COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: tde:TDE2302 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; PFAM: HD domain; metal dependent phosphohydrolase 2035308..2036432 Spirochaeta smaragdinae DSM 11293 9489980 YP_003803600.1 CDS Spirs_1880 NC_014364.1 2036429 2036791 D COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: dvl:Dvul_2148 hypothetical protein; PFAM: protein of unknown function UPF0102; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: conserved hypothetical protein TIGR00252; hypothetical protein 2036429..2036791 Spirochaeta smaragdinae DSM 11293 9489981 YP_003803601.1 CDS Spirs_1881 NC_014364.1 2036788 2036931 D KEGG: bhy:BHWA1_02006 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2036788..2036931 Spirochaeta smaragdinae DSM 11293 9489982 YP_003803602.1 CDS Spirs_1882 NC_014364.1 2036934 2037323 D KEGG: tpp:TPASS_0914 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2036934..2037323 Spirochaeta smaragdinae DSM 11293 9489983 YP_003803603.1 CDS Spirs_1883 NC_014364.1 2037339 2037857 D COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: cbe:Cbei_1926 PadR-like family transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: PadR family transcriptional regulator; PFAM: transcriptional regulator PadR-like family; PadR family transcriptional regulator 2037339..2037857 Spirochaeta smaragdinae DSM 11293 9489984 YP_003803604.1 CDS Spirs_1884 NC_014364.1 2037955 2038695 R InterPro IPR004155; KEGG: tde:TDE2349 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2037955..2038695) Spirochaeta smaragdinae DSM 11293 9489985 YP_003803605.1 CDS Spirs_1885 NC_014364.1 2038719 2039327 R KEGG: tde:TDE2350 lipoprotein; SPTR: lipoprotein; lipoprotein complement(2038719..2039327) Spirochaeta smaragdinae DSM 11293 9489986 YP_003803606.1 CDS Spirs_1886 NC_014364.1 2039424 2039903 D COGs: COG0669 phosphopantetheine adenylyltransferase; InterPro IPR001980:IPR004820:IPR004821; KEGG: tde:TDE1375 pantetheine-phosphate adenylyltransferase; PFAM: cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Pantetheine-phosphate adenylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase; cytidyltransferase-related domain protein; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain; pantetheine-phosphate adenylyltransferase 2039424..2039903 Spirochaeta smaragdinae DSM 11293 9489987 YP_003803607.1 CDS Spirs_1887 NC_014364.1 2039994 2040182 D COGs: COG0333 ribosomal protein L32; InterPro IPR002677; KEGG: tde:TDE1025 50S ribosomal protein L32; PFAM: ribosomal L32p protein; SPTR: 50S ribosomal protein L32; TIGRFAM: ribosomal protein L32; PFAM: ribosomal L32p protein family; TIGRFAM: ribosomal protein L32; 50S ribosomal protein L32 2039994..2040182 Spirochaeta smaragdinae DSM 11293 9489988 YP_003803608.1 CDS Spirs_1888 NC_014364.1 2040197 2040433 D COGs: COG0236 acyl carrier protein; InterPro IPR003231:IPR009081:IPR006163; KEGG: tde:TDE1026 acyl carrier protein; PFAM: phosphopantetheine-binding; SPTR: acyl carrier protein; TIGRFAM: acyl carrier protein; PFAM: phosphopantetheine attachment site; TIGRFAM: acyl carrier protein; acyl carrier protein 2040197..2040433 Spirochaeta smaragdinae DSM 11293 9489989 YP_003803609.1 CDS Spirs_1889 NC_014364.1 2040458 2041192 D COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR011907:IPR000999:IPR001159; KEGG: tde:TDE1027 ribonuclease III; PFAM: ribonuclease III; double-stranded RNA binding domain protein; PRIAM: ribonuclease III; SMART: ribonuclease III; double-stranded RNA binding domain protein; SPTR: ribonuclease 3; TIGRFAM: ribonuclease III; PFAM: RNase3 domain; Double-stranded RNA binding motif; TIGRFAM: ribonuclease III, bacterial; ribonuclease III 2040458..2041192 Spirochaeta smaragdinae DSM 11293 9489990 YP_003803610.1 CDS Spirs_1890 NC_014364.1 2041214 2042569 R COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR006674:IPR006675; KEGG: tde:TDE1033 polyA polymerase family protein; PFAM: polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; SPTR: polyA polymerase family protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; poly A polymerase head domain; TIGRFAM: uncharacterized domain HDIG; polynucleotide adenylyltransferase/metal dependent phosphohydrolase complement(2041214..2042569) Spirochaeta smaragdinae DSM 11293 9489991 YP_003803611.1 CDS Spirs_1891 NC_014364.1 2042661 2043533 R COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: tpp:TPASS_0792 flagellar filament 33 kDa core protein; PFAM: flagellin domain protein; SPTR: flagellar filament 33 kDa core protein; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein complement(2042661..2043533) Spirochaeta smaragdinae DSM 11293 9489992 YP_003803612.1 CDS Spirs_1892 NC_014364.1 2043729 2044769 D COGs: COG0205 6-phosphofructokinase; InterPro IPR000023:IPR012003; KEGG: bvu:BVU_1040 6-phosphofructokinase; PFAM: phosphofructokinase; SPTR: uncharacterized protein; PFAM: phosphofructokinase; TIGRFAM: phosphofructokinase; phosphofructokinase 2043729..2044769 Spirochaeta smaragdinae DSM 11293 9489993 YP_003803613.1 CDS Spirs_1893 NC_014364.1 2044800 2046866 D COGs: COG0855 polyphosphate kinase; InterPro IPR003414; KEGG: rbi:RB2501_12794 polyphosphate kinase; PFAM: polyphosphate kinase; PRIAM: polyphosphate kinase; SPTR: polyphosphate kinase; PFAM: polyphosphate kinase; polyphosphate kinase 2044800..2046866 Spirochaeta smaragdinae DSM 11293 9489994 YP_003803614.1 CDS Spirs_1894 NC_014364.1 2046942 2050064 D COGs: COG0060 isoleucyl-tRNA synthetase; InterPro IPR015905:IPR002300:IPR013155:IPR002301; KEGG: tde:TDE2663 isoleucyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; SPTR: isoleucine-tRNA ligase; TIGRFAM: isoleucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase; isoleucyl-tRNA synthetase 2046942..2050064 Spirochaeta smaragdinae DSM 11293 9489995 YP_003803615.1 CDS Spirs_1895 NC_014364.1 2050022 2050957 D KEGG: fre:Franean1_4793 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2050022..2050957 Spirochaeta smaragdinae DSM 11293 9489996 YP_003803616.1 CDS Spirs_1896 NC_014364.1 2050968 2051597 D COGs: COG0118 glutamine amidotransferase; InterPro IPR010139:IPR016226:IPR017926:IPR000991; KEGG: fsu:Fisuc_0632 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; SPTR: Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; PFAM: glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2050968..2051597 Spirochaeta smaragdinae DSM 11293 9489997 YP_003803617.1 CDS Spirs_1897 NC_014364.1 2051590 2052372 D COGs: COG0107 imidazoleglycerol-phosphate synthase; InterPro IPR006062:IPR004651; KEGG: dal:Dalk_2581 imidazole glycerol phosphate synthase subunit HisF; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; PFAM: histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit; imidazoleglycerol phosphate synthase, cyclase subunit 2051590..2052372 Spirochaeta smaragdinae DSM 11293 9489998 YP_003803618.1 CDS Spirs_1898 NC_014364.1 2052470 2052772 D COGs: COG2331 conserved hypothetical protein; InterPro IPR013429; KEGG: tde:TDE2661 hypothetical protein; PFAM: regulatory protein FmdB; SPTR: uncharacterized protein; TIGRFAM: regulatory protein, FmdB family; PFAM: Zinc ribbon domain; TIGRFAM: regulatory protein, FmdB family; regulatory protein, FmdB family 2052470..2052772 Spirochaeta smaragdinae DSM 11293 9489999 YP_003803619.1 CDS Spirs_1899 NC_014364.1 2052758 2053972 R COGs: COG0301 thiamine biosynthesis ATP pyrophosphatase; InterPro IPR003720:IPR004114:IPR020536; KEGG: tde:TDE2568 thiamine biosynthesis protein ThiI; PFAM: thiamine biosynthesis protein-like; THUMP domain protein; SPTR: thiamine biosynthesis protein ThiI; TIGRFAM: thiamine biosynthesis/tRNA modification protein ThiI; PFAM: thiamine biosynthesis protein (ThiI); THUMP domain; TIGRFAM: thiazole biosynthesis/tRNA modification protein ThiI; thiamine biosynthesis/tRNA modification protein ThiI complement(2052758..2053972) Spirochaeta smaragdinae DSM 11293 9490000 YP_003803620.1 CDS Spirs_1900 NC_014364.1 2053982 2055154 R COGs: COG1104 cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192; KEGG: tde:TDE0103 aminotransferase, class-V; PFAM: aminotransferase class V; PRIAM: cysteine desulfurase; SPTR: cysteine desulfurase; PFAM: Aminotransferase class-V; cysteine desulfurase complement(2053982..2055154) Spirochaeta smaragdinae DSM 11293 9490001 YP_003803621.1 CDS Spirs_1901 NC_014364.1 2055173 2055529 D COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: glo:Glov_1665 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: transcriptional regulator, ArsR family; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 2055173..2055529 Spirochaeta smaragdinae DSM 11293 9490002 YP_003803622.1 CDS Spirs_1902 NC_014364.1 2055553 2056602 D COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR016303:IPR002658; KEGG: reh:H16_A3434 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase protein; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase; 3-dehydroquinate synthase 2055553..2056602 Spirochaeta smaragdinae DSM 11293 9490003 YP_003803623.1 CDS Spirs_1903 NC_014364.1 2056609 2059137 R COGs: COG1643 HrpA-like helicase; InterProIPR014001:IPR001650:IPR000209:IPR002464:IPR 014021:IPR007502:IPR011709; KEGG: tde:TDE1654 ATP-dependent helicase HrpA, PFAM: protein of unknown function DUF1605; helicase-associated domain protein; helicase; SMART: DEAD-like helicase ; helicase domain protein; SPTR: ATP-dependent helicase HrpA, ; PFAM: Helicase conserved C-terminal domain; Helicase associated domain (HA2); Domain of unknown function (DUF1605); DEAD/DEAH box helicase; hypothetical protein complement(2056609..2059137) Spirochaeta smaragdinae DSM 11293 9490004 YP_003803624.1 CDS Spirs_1904 NC_014364.1 2059110 2060417 R COGs: COG0124 Histidyl-tRNA synthetase; InterProIPR015807:IPR004516:IPR006195:IPR002314:IPR 004154; KEGG: tde:TDE1442 histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); anticodon-binding domain protein; PRIAM: histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase; histidyl-tRNA synthetase complement(2059110..2060417) Spirochaeta smaragdinae DSM 11293 9490005 YP_003803625.1 CDS Spirs_1905 NC_014364.1 2060513 2061694 D COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR002646:IPR010206; KEGG: tde:TDE1726 polyA polymerase family protein; PFAM: polynucleotide adenylyltransferase region; SPTR: polyA polymerase family protein; TIGRFAM: poly(A) polymerase; PFAM: poly A polymerase head domain; TIGRFAM: poly(A) polymerase; poly(A) polymerase 2060513..2061694 Spirochaeta smaragdinae DSM 11293 9490006 YP_003803626.1 CDS Spirs_1906 NC_014364.1 2061710 2062942 R InterPro IPR019734:IPR013026; KEGG: emi:Emin_0539 TPR repeat-containing protein; SPTR: Tetratricopeptide repeat protein; PFAM: protein of unknown function (DUF1570); hypothetical protein complement(2061710..2062942) Spirochaeta smaragdinae DSM 11293 9490007 YP_003803627.1 CDS Spirs_1907 NC_014364.1 2063022 2063888 R KEGG: tde:TDE1967 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2063022..2063888) Spirochaeta smaragdinae DSM 11293 9490008 YP_003803628.1 CDS Spirs_1908 NC_014364.1 2064014 2065600 D KEGG: glo:Glov_2022 polar amino acid ABC transporter inner membrane subunit; SPTR: Polar amino acid ABC transporter inner membrane subunit; hypothetical protein 2064014..2065600 Spirochaeta smaragdinae DSM 11293 9490009 YP_003803629.1 CDS Spirs_1909 NC_014364.1 2065597 2066925 D COGs: COG4656 NADH:ubiquinone oxidoreductase subunit RnfC; InterProIPR017900:IPR017896:IPR011538:IPR019554:IPR 010208; KEGG: ctc:CTC01019 RnfC/NqrF; PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; SPTR: RnfC/nqrF; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; PFAM: Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: electron transport complex, RnfABCDGE type, C subunit; RnfABCDGE type electron transport complex subunit C 2065597..2066925 Spirochaeta smaragdinae DSM 11293 9490010 YP_003803630.1 CDS Spirs_1910 NC_014364.1 2066943 2068082 D COGs: COG4658 NADH:ubiquinone oxidoreductase subunit RnfD; InterPro IPR004338:IPR011303; KEGG: ckr:CKR_1161 hypothetical protein; PFAM: NQR2 and RnfD family protein; SPTR: electron transport complex, RnfABCDGE type, D subunit; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; PFAM: NQR2, RnfD, RnfE family; TIGRFAM: electron transport complex, RnfABCDGE type, D subunit; RnfABCDGE type electron transport complex subunit D 2066943..2068082 Spirochaeta smaragdinae DSM 11293 9490011 YP_003803631.1 CDS Spirs_1911 NC_014364.1 2068079 2068639 D COGs: COG4659 NADH:ubiquinone oxidoreductase subunit RnfG; InterPro IPR017441:IPR007329; KEGG: tit:Thit_0114 electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain protein; SPTR: electron transport complex, RnfABCDGE type, G subunit; PFAM: FMN-binding domain; TIGRFAM: electron transport complex, RnfABCDGE type, G subunit; FMN-binding domain-containing protein 2068079..2068639 Spirochaeta smaragdinae DSM 11293 9490012 YP_003803632.1 CDS Spirs_1912 NC_014364.1 2068641 2069261 D COGs: COG4660 NADH:ubiquinone oxidoreductase subunit RnfE; InterPro IPR003667:IPR010968; KEGG: fnu:FN1593 electron transport complex RsxE subunit; PFAM: RnfA-Nqr electron transport subunit; SPTR: SoxR-reducing system protein RsxE; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, E subunit; RnfABCDGE type electron transport complex subunit E 2068641..2069261 Spirochaeta smaragdinae DSM 11293 9490013 YP_003803633.1 CDS Spirs_1913 NC_014364.1 2069263 2069853 D COGs: COG4657 NADH:ubiquinone oxidoreductase subunit RnfA; InterPro IPR003667:IPR011293; KEGG: fnu:FN1592 Na(+)-translocating NADH-quinone reductase subunit D; PFAM: RnfA-Nqr electron transport subunit; SPTR: Na(+)-translocating NADH-quinone reductase subunit D; TIGRFAM: electron transport complex, RnfABCDGE type, subunit alpha; PFAM: Rnf-Nqr subunit, membrane protein; TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; RnfABCDGE type electron transport complex subunit alpha 2069263..2069853 Spirochaeta smaragdinae DSM 11293 9490014 YP_003803634.1 CDS Spirs_1914 NC_014364.1 2069866 2070699 D COGs: COG2878 NADH:ubiquinone oxidoreductase subunit RnfB; InterProIPR017900:IPR017896:IPR007202:IPR001450:IPR 010207; KEGG: drt:Dret_2474 electron transport complex, RnfABCDGE type subunit beta; PFAM: Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: electron transport complex, RnfABCDGE type subunit beta; TIGRFAM: electron transport complex, RnfABCDGE type subunit beta; PFAM: Fe-S cluster; 4Fe-4S binding domain; TIGRFAM: electron transport complex, RnfABCDGE type subunit beta; RnfABCDGE type electron transport complex subunit beta 2069866..2070699 Spirochaeta smaragdinae DSM 11293 9490015 YP_003803635.1 CDS Spirs_1915 NC_014364.1 2070686 2072710 D InterPro IPR015178:IPR004300:IPR015179; KEGG: dth:DICTH_0745 alpha-amylase 1; PFAM: glycoside hydrolase family 57; Domain of unknown function DUF1925; Domain of unknown function DUF1926; PRIAM: 4-alpha-glucanotransferase; SPTR: alpha-amylase 1; PFAM: Domain of unknown function (DUF1925); glycosyl hydrolase family 57; Domain of unknown function (DUF1926); 4-alpha-glucanotransferase 2070686..2072710 Spirochaeta smaragdinae DSM 11293 9490016 YP_003803636.1 CDS Spirs_1916 NC_014364.1 2072732 2073958 R KEGG: tde:TDE1245 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2072732..2073958) Spirochaeta smaragdinae DSM 11293 9490017 YP_003803637.1 CDS Spirs_1917 NC_014364.1 2074025 2074297 D InterPro IPR003799; KEGG: tde:TDE2047 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein Cas2; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated protein Cas2; CRISPR-associated protein Cas2 2074025..2074297 Spirochaeta smaragdinae DSM 11293 9490018 YP_003803638.1 CDS Spirs_1918 NC_014364.1 2074409 2075428 D COGs: COG1186 protein chain release factor B; InterPro IPR000352:IPR005139:IPR004374; KEGG: tpp:TPASS_0576 peptide chain release factor 2; PFAM: class I peptide chain release factor; PCRF domain protein; SPTR: peptide chain release factor 2; TIGRFAM: peptide chain release factor 2; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2; peptide chain release factor 2 2074409..2075428 Spirochaeta smaragdinae DSM 11293 9490019 YP_003803639.1 CDS Spirs_1919 NC_014364.1 2075430 2075807 D COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: csc:Csac_1271 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein 2075430..2075807 Spirochaeta smaragdinae DSM 11293 9490020 YP_003803640.1 CDS Spirs_1920 NC_014364.1 2075804 2077264 D InterPro IPR013229; KEGG: dth:DICTH_1706 hypothetical protein; PFAM: PEGA domain protein; SPTR: uncharacterized protein; PFAM: PEGA domain; PEGA domain-containing protein 2075804..2077264 Spirochaeta smaragdinae DSM 11293 9490021 YP_003803641.1 CDS Spirs_1921 NC_014364.1 2077265 2078140 D COGs: COG0552 Signal recognition particle GTPase; InterPro IPR003593:IPR000897:IPR013822:IPR004390; KEGG: tde:TDE2043 signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54 G- domain; GTP-binding signal recognition particle SRP54 helical bundle; SMART: ATPase AAA; SPTR: Signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY; signal recognition particle-docking protein FtsY 2077265..2078140 Spirochaeta smaragdinae DSM 11293 9490022 YP_003803642.1 CDS Spirs_1922 NC_014364.1 2078151 2079197 D KEGG: rmr:Rmar_2754 transcription-repair coupling factor; SPTR: transcription-repair coupling factor; manually curated; hypothetical protein 2078151..2079197 Spirochaeta smaragdinae DSM 11293 9490023 YP_003803643.1 CDS Spirs_1923 NC_014364.1 2079184 2080530 D COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838; KEGG: tde:TDE2041 lipoprotein releasing system, permease, PFAM: protein of unknown function DUF214; SPTR: Lipoprotein releasing system, permease, ; PFAM: Predicted permease; hypothetical protein 2079184..2080530 Spirochaeta smaragdinae DSM 11293 9490024 YP_003803644.1 CDS Spirs_1924 NC_014364.1 2080549 2081238 D COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR017871:IPR003439:IPR015854; KEGG: tde:TDE2040 lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Lipoprotein-releasing system ATP-binding protein LolD; PFAM: ABC transporter; ABC transporter 2080549..2081238 Spirochaeta smaragdinae DSM 11293 9490025 YP_003803645.1 CDS Spirs_1925 NC_014364.1 2081235 2082539 D COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838; KEGG: tde:TDE2039 lipoprotein releasing system, permease, PFAM: protein of unknown function DUF214; SPTR: lipoprotein releasing system, permease protein; PFAM: Predicted permease; hypothetical protein 2081235..2082539 Spirochaeta smaragdinae DSM 11293 9490026 YP_003803646.1 CDS Spirs_1926 NC_014364.1 2082567 2083064 D COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR017969:IPR001943; KEGG: ckr:CKR_0154 hypothetical protein; PFAM: UvrB/UvrC protein; SPTR: UvrB/UvrC protein; PFAM: UvrB/uvrC motif; UvrB/UvrC protein 2082567..2083064 Spirochaeta smaragdinae DSM 11293 9490027 YP_003803647.1 CDS Spirs_1927 NC_014364.1 2083064 2084089 D COGs: COG3869 Arginine kinase; InterPro IPR000749; KEGG: hmo:HM1_1343 ATP:guanido phosphotransferase, PFAM: ATP:guanido phosphotransferase; SPTR: ATP:guanido phosphotransferase, ; PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain; ATP:guanido phosphotransferase 2083064..2084089 Spirochaeta smaragdinae DSM 11293 9490028 YP_003803648.1 CDS Spirs_1928 NC_014364.1 2084082 2086619 D COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR001270:IPR003593:IPR018368:IPR001943:IPR 004176:IPR003959:IPR013093:IPR019489; KEGG: gwc:GWCH70_0083 ATPase AAA-2 domain protein; PFAM: ATPase AAA; Clp domain protein; AAA ATPase central domain protein; UvrB/UvrC protein; Clp ATPase-like; SMART: AAA ATPase; SPTR: ATPase AAA; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; UvrB/uvrC motif; ATPase family associated with various cellular activities (AAA); ATPase AAA 2084082..2086619 Spirochaeta smaragdinae DSM 11293 9490029 YP_003803649.1 CDS Spirs_1929 NC_014364.1 2086623 2087255 D COGs: COG2176 DNA polymerase III subunit alpha (gram-positive type); InterPro IPR006055:IPR013520:IPR006054; KEGG: cth:Cthe_0996 DNA polymerase III PolC; PFAM: exonuclease RNase T and DNA polymerase III; PRIAM: DNA-directed DNA polymerase; SMART: exonuclease; SPTR: DNA polymerase III subunit alpha; TIGRFAM: DNA polymerase III epsilon subunit; PFAM: exonuclease; TIGRFAM: exonuclease, DNA polymerase III epsilon subunit family; DNA polymerase III subunit epsilon 2086623..2087255 Spirochaeta smaragdinae DSM 11293 9490030 YP_003803650.1 CDS Spirs_1930 NC_014364.1 2087252 2088181 D COGs: COG1234 metal-dependent hydrolase of the beta-lactamase superfamily III; InterPro IPR013471; KEGG: tde:TDE1951 ribonuclease Z; SPTR: ribonuclease Z; TIGRFAM: ribonuclease Z; PFAM: metallo-beta-lactamase superfamily; TIGRFAM: ribonuclease Z; ribonuclease Z 2087252..2088181 Spirochaeta smaragdinae DSM 11293 9490031 YP_003803651.1 CDS Spirs_1931 NC_014364.1 2088200 2089363 R InterPro IPR000160; KEGG: tde:TDE1456 GGDEF domain-containing protein; SPTR: GGDEF domain protein; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(2088200..2089363) Spirochaeta smaragdinae DSM 11293 9490032 YP_003803652.1 CDS Spirs_1932 NC_014364.1 2089423 2090274 D COGs: COG1355 dioxygenase; InterPro IPR002737; KEGG: dal:Dalk_4100 protein of unknown function DUF52; PFAM: protein of unknown function DUF52; SPTR: uncharacterized protein; PFAM: Memo-like protein; hypothetical protein 2089423..2090274 Spirochaeta smaragdinae DSM 11293 9490033 YP_003803653.1 CDS Spirs_1933 NC_014364.1 2090262 2091935 R COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tde:TDE1457 hypothetical protein; PFAM: protein of unknown function DUF115; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF115; hypothetical protein complement(2090262..2091935) Spirochaeta smaragdinae DSM 11293 9490034 YP_003803654.1 CDS Spirs_1934 NC_014364.1 2091913 2093514 R InterPro IPR002826; KEGG: tde:TDE1458 hypothetical protein; PFAM: protein of unknown function DUF115; SPTR: Conserved domain protein; PFAM: protein of unknown function DUF115; hypothetical protein complement(2091913..2093514) Spirochaeta smaragdinae DSM 11293 9490035 YP_003803655.1 CDS Spirs_1935 NC_014364.1 2093517 2094467 R KEGG: mcc:710668 similar to K06A9.1b; SPTR: DNA gyrase subunit B; hypothetical protein complement(2093517..2094467) Spirochaeta smaragdinae DSM 11293 9490036 YP_003803656.1 CDS Spirs_1936 NC_014364.1 2094464 2097532 R KEGG: mgm:Mmc1_3605 hypothetical protein; SPTR: MJ0042 family finger-like protein; hypothetical protein complement(2094464..2097532) Spirochaeta smaragdinae DSM 11293 9490037 YP_003803657.1 CDS Spirs_1937 NC_014364.1 2097684 2098127 D InterPro IPR007060; KEGG: tde:TDE1461 septum formation initiator family protein; PFAM: septum formation initiator; SPTR: septum formation initiator family protein; PFAM: septum formation initiator; septum formation initiator 2097684..2098127 Spirochaeta smaragdinae DSM 11293 9490038 YP_003803658.1 CDS Spirs_1938 NC_014364.1 2098124 2098699 D COGs: COG0009 translation factor (SUA5); InterPro IPR006070:IPR004388; KEGG: tde:TDE1462 SUA5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC domain; SPTR: Sua5/YciO/YrdC/YwlC family protein; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: yrdC domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; Sua5/YciO/YrdC/YwlC family protein 2098124..2098699 Spirochaeta smaragdinae DSM 11293 9490039 YP_003803659.1 CDS Spirs_1939 NC_014364.1 2098734 2100065 R InterPro IPR008323; KEGG: cth:Cthe_3196 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1015); hypothetical protein complement(2098734..2100065) Spirochaeta smaragdinae DSM 11293 9490040 YP_003803660.1 CDS Spirs_1940 NC_014364.1 2100164 2100790 D COGs: COG1564 thiamine pyrophosphokinase; InterPro IPR007371:IPR006282; KEGG: tpp:TPASS_0518 hypothetical protein; PFAM: Thiamin pyrophosphokinase catalytic region; SPTR: uncharacterized protein; TIGRFAM: thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase; thiamine pyrophosphokinase 2100164..2100790 Spirochaeta smaragdinae DSM 11293 9490041 YP_003803661.1 CDS Spirs_1941 NC_014364.1 2100809 2102602 D KEGG: baf:BAPKO_0750 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2100809..2102602 Spirochaeta smaragdinae DSM 11293 9490042 YP_003803662.1 CDS Spirs_1942 NC_014364.1 2102583 2103077 R COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: lbf:LBF_1710 HIT family hydrolase; PFAM: histidine triad (HIT) protein; SPTR: hydrolase; PFAM: HIT domain; histidine triad (HIT) protein complement(2102583..2103077) Spirochaeta smaragdinae DSM 11293 9490043 YP_003803663.1 CDS Spirs_1943 NC_014364.1 2103088 2103891 R KEGG: tde:TDE2492 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2103088..2103891) Spirochaeta smaragdinae DSM 11293 9490044 YP_003803664.1 CDS Spirs_1944 NC_014364.1 2103888 2104844 R COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834; KEGG: dol:Dole_0492 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: haloacid dehalogenase; PFAM: haloacid dehalogenase-like hydrolase; haloacid dehalogenase complement(2103888..2104844) Spirochaeta smaragdinae DSM 11293 9490045 YP_003803665.1 CDS Spirs_1945 NC_014364.1 2104962 2105219 D KEGG: aoe:Clos_2117 membrane-bound metal-dependent hydrolase; SPTR: uncharacterized protein; hypothetical protein 2104962..2105219 Spirochaeta smaragdinae DSM 11293 9490046 YP_003803666.1 CDS Spirs_1946 NC_014364.1 2105222 2105971 D COGs: COG0024 methionine aminopeptidase; InterPro IPR001714:IPR000994:IPR002467; KEGG: ank:AnaeK_1955 methionine aminopeptidase, type I; PFAM: peptidase M24; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I; methionine aminopeptidase, type I 2105222..2105971 Spirochaeta smaragdinae DSM 11293 9490047 YP_003803667.1 CDS Spirs_1948 NC_014364.1 2106798 2107019 D KEGG: dvm:DvMF_0349 preprotein translocase subunit SecG; SPTR: Preprotein translocase, SecG subunit; hypothetical protein 2106798..2107019 Spirochaeta smaragdinae DSM 11293 9490049 YP_003803668.1 CDS Spirs_1949 NC_014364.1 2107254 2108183 D COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752; KEGG: sli:Slin_2608 2-dehydropantoate 2-reductase; PFAM: ketopantoate reductase; SPTR: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase; ketopantoate reductase 2107254..2108183 Spirochaeta smaragdinae DSM 11293 9490050 YP_003803669.1 CDS Spirs_1950 NC_014364.1 2108367 2109227 D InterPro IPR001119; KEGG: pjd:Pjdr2_1173 S-layer domain protein; PFAM: S-layer domain protein; SPTR: S-layer domain protein; PFAM: S-layer homology domain; S-layer domain-containing protein 2108367..2109227 Spirochaeta smaragdinae DSM 11293 9490051 YP_003803670.1 CDS Spirs_1952 NC_014364.1 2109776 2110222 R KEGG: cno:NT01CX_0018 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1284); hypothetical protein complement(2109776..2110222) Spirochaeta smaragdinae DSM 11293 9490053 YP_003803671.1 CDS Spirs_1953 NC_014364.1 2110307 2110852 R InterPro IPR000462; KEGG: ckr:CKR_2027 hypothetical protein; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase complement(2110307..2110852) Spirochaeta smaragdinae DSM 11293 9490054 YP_003803672.1 CDS Spirs_1955 NC_014364.1 2111685 2112812 D InterPro IPR013378; KEGG: geo:Geob_1283 outer membrane adhesin like proteiin; PFAM: Listeria/Bacterioides repeat protein; SPTR: cell wall/surface repeat protein; TIGRFAM: cell wall/surface repeat protein; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); TIGRFAM: Listeria/Bacterioides repeat; cell wall/surface repeat protein 2111685..2112812 Spirochaeta smaragdinae DSM 11293 9490056 YP_003803673.1 CDS Spirs_1956 NC_014364.1 2112814 2115105 D InterPro IPR003961:IPR013378; KEGG: geo:Geob_1283 outer membrane adhesin like proteiin; PFAM: Fibronectin type III domain protein; Listeria/Bacterioides repeat protein; SMART: Fibronectin type III domain protein; SPTR: cell wall/surface repeat protein; TIGRFAM: cell wall/surface repeat protein; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); Fibronectin type III domain; TIGRFAM: Listeria/Bacterioides repeat; cell wall/surface repeat protein 2112814..2115105 Spirochaeta smaragdinae DSM 11293 9490057 YP_003803674.1 CDS Spirs_1957 NC_014364.1 2115403 2116614 R COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR020449:IPR018060:IPR018062:IPR000005; KEGG: dal:Dalk_0029 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: AraC family transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(2115403..2116614) Spirochaeta smaragdinae DSM 11293 9490058 YP_003803675.1 CDS Spirs_1958 NC_014364.1 2116875 2117300 D COGs: COG3744 conserved hypothetical protein; KEGG: lic:LIC12713 hypothetical protein; SPTR: uncharacterized protein; PFAM: PIN domain; hypothetical protein 2116875..2117300 Spirochaeta smaragdinae DSM 11293 9490059 YP_003803676.1 CDS Spirs_1959 NC_014364.1 2117419 2118084 D COGs: COG3153 acetyltransferase; InterPro IPR000182; KEGG: mba:Mbar_A3726 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 2117419..2118084 Spirochaeta smaragdinae DSM 11293 9490060 YP_003803677.1 CDS Spirs_1960 NC_014364.1 2118589 2118939 R KEGG: lrh:LGG_01027 type III DNA restriction-modification system; SPTR: Restriction endonuclease; hypothetical protein complement(2118589..2118939) Spirochaeta smaragdinae DSM 11293 9490061 YP_003803678.1 CDS Spirs_1961 NC_014364.1 2119034 2119798 D COGs: COG1864 DNA/RNA endonuclease G NUC1; InterPro IPR020821:IPR018524:IPR001604; KEGG: cts:Ctha_1807 DNA/RNA non-specific endonuclease; PFAM: DNA/RNA non-specific endonuclease; SMART: extracellular endonuclease, subunit A; SPTR: DNA/RNA non-specific endonuclease; PFAM: DNA/RNA non-specific endonuclease; DNA/RNA non-specific endonuclease 2119034..2119798 Spirochaeta smaragdinae DSM 11293 9490062 YP_003803679.1 CDS Spirs_1962 NC_014364.1 2119848 2121035 R COGs: COG3328 transposase and inactivated derivatives; InterPro IPR001207; KEGG: glo:Glov_3450 transposase mutator type; PFAM: transposase mutator type; SPTR: transposase mutator type; PFAM: transposase, Mutator family; transposase mutator type complement(2119848..2121035) Spirochaeta smaragdinae DSM 11293 9490063 YP_003803680.1 CDS Spirs_1964 NC_014364.1 2121424 2123298 R KEGG: hmo:HM1_1329 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2121424..2123298) Spirochaeta smaragdinae DSM 11293 9490065 YP_003803681.1 CDS Spirs_1965 NC_014364.1 2123295 2124836 R KEGG: hmo:HM1_1330 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2123295..2124836) Spirochaeta smaragdinae DSM 11293 9490066 YP_003803682.1 CDS Spirs_1966 NC_014364.1 2124849 2126519 R COGs: COG0433 ATPase; KEGG: hmo:HM1_1331 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2124849..2126519) Spirochaeta smaragdinae DSM 11293 9490067 YP_003803683.1 CDS Spirs_1967 NC_014364.1 2126533 2127723 R KEGG: hmo:HM1_1332 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2126533..2127723) Spirochaeta smaragdinae DSM 11293 9490068 YP_003803684.1 CDS Spirs_1968 NC_014364.1 2127926 2128306 R KEGG: tde:TDE1170 DNA-binding protein; SPTR: DNA-binding protein; manually curated; PFAM: bacteriophage CI repressor helix-turn-helix domain; DNA-binding protein complement(2127926..2128306) Spirochaeta smaragdinae DSM 11293 9490069 YP_003803685.1 CDS Spirs_1969 NC_014364.1 2128620 2128988 D InterPro IPR000551:IPR010093; KEGG: deh:cbdb_A1300 excisionase family DNA-binding protein; PFAM: regulatory protein MerR; SPTR: DNA-binding protein, excisionase family; TIGRFAM: DNA binding domain protein, excisionase family; TIGRFAM: DNA binding domain, excisionase family; excisionase family DNA binding domain-containing protein 2128620..2128988 Spirochaeta smaragdinae DSM 11293 9490070 YP_003803686.1 CDS Spirs_1970 NC_014364.1 2129017 2129205 D KEGG: bbo:BBOV_I004210 spherical body protein 3; hypothetical protein 2129017..2129205 Spirochaeta smaragdinae DSM 11293 9490071 YP_003803687.1 CDS Spirs_1971 NC_014364.1 2129450 2129836 D COGs: COG0338 Site-specific DNA methylase; InterPro IPR002294:IPR012327; KEGG: bte:BTH_II1068 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: D12 class N6 adenine-specific DNA methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; D12 class N6 adenine-specific DNA methyltransferase 2129450..2129836 Spirochaeta smaragdinae DSM 11293 9490072 YP_003803688.1 CDS Spirs_1972 NC_014364.1 2130317 2130664 D KEGG: ath:AT1G13730 nuclear transport factor 2 (NTF2) family protein / RNA recognition motif (RRM)-containing protein; SPTR: At1g13730; hypothetical protein 2130317..2130664 Spirochaeta smaragdinae DSM 11293 9490073 YP_003803689.1 CDS Spirs_1973 NC_014364.1 2130661 2131533 D InterPro IPR018330:IPR010183; KEGG: hth:HTH_0517 phage recombination protein; PFAM: DNA single-strand annealing protein RecT-like; SPTR: Phage recombination protein; TIGRFAM: phage recombination protein Bet; PFAM: RecT family; TIGRFAM: phage recombination protein Bet; phage recombination protein Bet 2130661..2131533 Spirochaeta smaragdinae DSM 11293 9490074 YP_003803690.1 CDS Spirs_1974 NC_014364.1 2131552 2132241 D KEGG: dvl:Dvul_1041 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2131552..2132241 Spirochaeta smaragdinae DSM 11293 9490075 YP_003803691.1 CDS Spirs_1975 NC_014364.1 2132238 2132714 D KEGG: hmu:Hmuk_1730 DNA methyltransferase; SPTR: DNA methyltransferase; hypothetical protein 2132238..2132714 Spirochaeta smaragdinae DSM 11293 9490076 YP_003803692.1 CDS Spirs_1976 NC_014364.1 2132711 2133103 D KEGG: ses:SARI_02660 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2132711..2133103 Spirochaeta smaragdinae DSM 11293 9490077 YP_003803693.1 CDS Spirs_1977 NC_014364.1 2133113 2133715 D COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: tde:TDE1677 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein 2133113..2133715 Spirochaeta smaragdinae DSM 11293 9490078 YP_003803694.1 CDS Spirs_1978 NC_014364.1 2133728 2134816 D KEGG: ate:Athe_2433 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2133728..2134816 Spirochaeta smaragdinae DSM 11293 9490079 YP_003803695.1 CDS Spirs_1979 NC_014364.1 2134821 2135222 D KEGG: bbo:BBOV_I000040 variant erythrocyte surface antigen-1 subunit beta; SPTR: Variant erythrocyte surface antigen-1, beta subunit; hypothetical protein 2134821..2135222 Spirochaeta smaragdinae DSM 11293 9490080 YP_003803696.1 CDS Spirs_1980 NC_014364.1 2135206 2135424 D KEGG: ptm:GSPATT00031175001 hypothetical protein; SPTR: chromosome undetermined scaffold_121, whole genome shotgun sequence; hypothetical protein 2135206..2135424 Spirochaeta smaragdinae DSM 11293 9490081 YP_003803697.1 CDS Spirs_1981 NC_014364.1 2135421 2135612 D hypothetical protein 2135421..2135612 Spirochaeta smaragdinae DSM 11293 9490082 YP_003803698.1 CDS Spirs_1982 NC_014364.1 2135636 2135815 D hypothetical protein 2135636..2135815 Spirochaeta smaragdinae DSM 11293 9490083 YP_003803699.1 CDS Spirs_1983 NC_014364.1 2135958 2136674 D KEGG: vex:VEA_000465 fibronectin type III domain protein; SPTR: Ig family protein; hypothetical protein 2135958..2136674 Spirochaeta smaragdinae DSM 11293 9490084 YP_003803700.1 CDS Spirs_1984 NC_014364.1 2136982 2137380 D KEGG: dvu:DVU1505 holin, SPTR: Holin; hypothetical protein 2136982..2137380 Spirochaeta smaragdinae DSM 11293 9490085 YP_003803701.1 CDS Spirs_1985 NC_014364.1 2137384 2137893 D COGs: COG3747 Phage terminase small subunit; InterPro IPR006448; KEGG: spa:M6_Spy1142 phage terminase small subunit; PFAM: terminase small subunit P27; SPTR: Phage terminase Small Subunit; TIGRFAM: phage terminase, small subunit, , P27 family; PFAM: Phage terminase, small subunit; TIGRFAM: phage terminase, small subunit, , P27 family; phage terminase, small subunit, , P27 family 2137384..2137893 Spirochaeta smaragdinae DSM 11293 9490086 YP_003803702.1 CDS Spirs_1986 NC_014364.1 2137890 2139611 D COGs: COG4626 Phage terminase-like protein large subunit; InterPro IPR005021; KEGG: pag:PLES_25381 terminase; PFAM: terminase; SPTR: terminase; PFAM: Phage terminase; terminase 2137890..2139611 Spirochaeta smaragdinae DSM 11293 9490087 YP_003803703.1 CDS Spirs_1987 NC_014364.1 2139608 2140849 D COGs: COG4695 Phage-related protein; InterPro IPR006944:IPR006427; KEGG: spa:M6_Spy1140 portal protein; PFAM: portal protein; SPTR: Phage portal protein, HK97 family; TIGRFAM: phage portal protein, HK97 family; PFAM: Phage portal protein; TIGRFAM: phage portal protein, HK97 family; phage portal protein, HK97 family 2139608..2140849 Spirochaeta smaragdinae DSM 11293 9490088 YP_003803704.1 CDS Spirs_1988 NC_014364.1 2140839 2141672 D COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: eck:EC55989_1063 ATP-dependent Clp protease proteolytic subunit (endopeptidase Clp) of prophage; PFAM: peptidase S14 ClpP; SPTR: ATP-dependent Clp protease proteolytic subunit; PFAM: Clp protease; peptidase S14 ClpP 2140839..2141672 Spirochaeta smaragdinae DSM 11293 9490089 YP_003803705.1 CDS Spirs_1989 NC_014364.1 2141673 2142872 D COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; InterPro IPR006444; KEGG: avi:Avi_1338 phage major capsid protein HK97 family; PFAM: major capsid protein HK97; SPTR: Phage major capsid protein HK97 family; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; TIGRFAM: phage major capsid protein, HK97 family; phage major capsid protein, HK97 family 2141673..2142872 Spirochaeta smaragdinae DSM 11293 9490090 YP_003803706.1 CDS Spirs_1990 NC_014364.1 2142889 2143311 D InterPro IPR013838; KEGG: avi:Avi_6187 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2142889..2143311 Spirochaeta smaragdinae DSM 11293 9490091 YP_003803707.1 CDS Spirs_1991 NC_014364.1 2143390 2143947 D KEGG: ngk:NGK_1435 phage associated protein; SPTR: uncharacterized protein; TIGRFAM: phage conserved hypothetical protein, phiE125 gp8 family; hypothetical protein 2143390..2143947 Spirochaeta smaragdinae DSM 11293 9490092 YP_003803708.1 CDS Spirs_1992 NC_014364.1 2143944 2144369 D KEGG: mba:Mbar_A3399 hypothetical protein; SPTR: Phage protein, HK97 gp10 family; PFAM: bacteriophage protein of unknown function (DUF646); hypothetical protein 2143944..2144369 Spirochaeta smaragdinae DSM 11293 9490093 YP_003803709.1 CDS Spirs_1993 NC_014364.1 2144347 2144745 D KEGG: ech:ECH_1012 DNA-binding response regulator; SPTR: response regulator component of a two-component regulatory system; hypothetical protein 2144347..2144745 Spirochaeta smaragdinae DSM 11293 9490094 YP_003803710.1 CDS Spirs_1994 NC_014364.1 2144749 2145444 D KEGG: npu:Npun_F4869 outer membrane adhesin like proteiin; SPTR: FG-GAP repeat protein; hypothetical protein 2144749..2145444 Spirochaeta smaragdinae DSM 11293 9490095 YP_003803711.1 CDS Spirs_1995 NC_014364.1 2145447 2145848 D KEGG: gga:396040 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; SPTR: BRM protein; hypothetical protein 2145447..2145848 Spirochaeta smaragdinae DSM 11293 9490096 YP_003803712.1 CDS Spirs_1996 NC_014364.1 2145869 2146144 D KEGG: cwo:Cwoe_2446 hypothetical protein; hypothetical protein 2145869..2146144 Spirochaeta smaragdinae DSM 11293 9490097 YP_003803713.1 CDS Spirs_1997 NC_014364.1 2146125 2148398 D KEGG: cth:Cthe_1709 phage-related protein-like protein; SPTR: uncharacterized protein; hypothetical protein 2146125..2148398 Spirochaeta smaragdinae DSM 11293 9490098 YP_003803714.1 CDS Spirs_1998 NC_014364.1 2148401 2151679 D KEGG: baf:BAPKO_5508 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2148401..2151679 Spirochaeta smaragdinae DSM 11293 9490099 YP_003803715.1 CDS Spirs_1999 NC_014364.1 2151676 2152287 D KEGG: bam:Bamb_1861 bacteriophage-acquired protein; SPTR: bacteriophage-acquired protein; hypothetical protein 2151676..2152287 Spirochaeta smaragdinae DSM 11293 9490100 YP_003803716.1 CDS Spirs_2000 NC_014364.1 2152292 2152525 D KEGG: tva:TVAG_483670 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2152292..2152525 Spirochaeta smaragdinae DSM 11293 9490101 YP_003803717.1 CDS Spirs_2001 NC_014364.1 2152527 2152997 D KEGG: bdu:BDU_12007 BppB; SPTR: BppB; PFAM: protein of unknown function, DUF261; hypothetical protein 2152527..2152997 Spirochaeta smaragdinae DSM 11293 9490102 YP_003803718.1 CDS Spirs_2002 NC_014364.1 2152994 2153242 D KEGG: cel:C11D2.6 Novel Channel type/ Nematode CAlcium channel; SPTR: Uncoordinated protein 77, isoform c, partially confirmed by transcript evidence; hypothetical protein 2152994..2153242 Spirochaeta smaragdinae DSM 11293 9490103 YP_003803719.1 CDS Spirs_2003 NC_014364.1 2153244 2153633 D KEGG: ptr:463470 CAP-GLY domain containing linker protein 2; SPTR: CAP-GLY domain containing linker protein 2; hypothetical protein 2153244..2153633 Spirochaeta smaragdinae DSM 11293 9490104 YP_003803720.1 CDS Spirs_2004 NC_014364.1 2153947 2154315 D KEGG: ddi:DDBDRAFT_0187706 hypothetical protein; SPTR: integron gene cassette protein; hypothetical protein 2153947..2154315 Spirochaeta smaragdinae DSM 11293 9490105 YP_003803721.1 CDS Spirs_2005 NC_014364.1 2154496 2154795 D KEGG: swd:Swoo_4306 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2154496..2154795 Spirochaeta smaragdinae DSM 11293 9490106 YP_003803722.1 CDS Spirs_2006 NC_014364.1 2155051 2155953 D COGs: COG1284 conserved hypothetical protein; InterPro IPR003740:IPR019264; KEGG: dap:Dacet_1948 hypothetical protein; PFAM: protein of unknown function DUF2179; protein of unknown function DUF161; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179); hypothetical protein 2155051..2155953 Spirochaeta smaragdinae DSM 11293 9490107 YP_003803723.1 CDS Spirs_R0031 NC_014364.1 2156093 2157334 R InterPro IPR002104; KEGG: mta:Moth_1796 phage integrase; PFAM: integrase family protein; SPTR: Integrase family protein; tmRNA as predicted by Rfam (RF00023), score 192.43; PFAM: Phage integrase family; integrase family protein complement(2156093..2157334) Spirochaeta smaragdinae DSM 11293 9490108 YP_003803724.1 CDS Spirs_2008 NC_014364.1 2157887 2159014 D COGs: COG1597 Sphingosine kinase; KEGG: bpf:BpOF4_01970 hypothetical protein; SPTR: uncharacterized protein; PFAM: diacylglycerol kinase catalytic domain; Sphingosine kinase 2157887..2159014 Spirochaeta smaragdinae DSM 11293 9490109 YP_003803725.1 CDS Spirs_2009 NC_014364.1 2159041 2159577 R COGs: COG0691 tmRNA-binding protein; InterPro IPR000037:IPR020081; KEGG: tde:TDE1464 SsrA-binding protein; PFAM: SmpB protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein; SsrA-binding protein complement(2159041..2159577) Spirochaeta smaragdinae DSM 11293 9490110 YP_003803726.1 CDS Spirs_2010 NC_014364.1 2159517 2161133 R COGs: COG1262 conserved hypothetical protein; InterPro IPR013229:IPR005532; KEGG: btu:BT0032 hypothetical protein; PFAM: protein of unknown function DUF323; PEGA domain protein; SPTR: uncharacterized protein; PFAM: Formylglycine-generating sulfatase enzyme; PEGA domain; hypothetical protein complement(2159517..2161133) Spirochaeta smaragdinae DSM 11293 9490111 YP_003803727.1 CDS Spirs_2011 NC_014364.1 2161198 2162172 D COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: baf:BAPKO_0030 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S26; peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; signal peptidase I 2161198..2162172 Spirochaeta smaragdinae DSM 11293 9490112 YP_003803728.1 CDS Spirs_2012 NC_014364.1 2162169 2162930 D InterPro IPR000223; KEGG: tde:TDE1465 signal peptidase I, SPTR: Signal peptidase I, ; TIGRFAM: signal peptidase I; TIGRFAM: signal peptidase I, bacterial type; signal peptidase I 2162169..2162930 Spirochaeta smaragdinae DSM 11293 9490113 YP_003803729.1 CDS Spirs_2013 NC_014364.1 2162935 2164113 D COGs: COG0635 coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR010723:IPR004559; KEGG: smb:smi_0720 coproporphyrinogen III oxidase oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: coproporphyrinogen III oxidase oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; PFAM: radical SAM superfamily; HemN C-terminal region; TIGRFAM: oxygen-independent coproporphyrinogen III oxidase; oxygen-independent coproporphyrinogen III oxidase 2162935..2164113 Spirochaeta smaragdinae DSM 11293 9490114 YP_003803730.1 CDS Spirs_2014 NC_014364.1 2164179 2164925 D COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: tde:TDE1487 hypothetical protein; PFAM: protein of unknown function DUF28; SPTR: UPF0082 protein TDE_1487; PFAM: Domain of unknown function DUF28; TIGRFAM: conserved hypothetical protein TIGR01033; hypothetical protein 2164179..2164925 Spirochaeta smaragdinae DSM 11293 9490115 YP_003803731.1 CDS Spirs_2015 NC_014364.1 2164922 2165425 D COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176; KEGG: tde:TDE1864 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC; crossover junction endodeoxyribonuclease RuvC 2164922..2165425 Spirochaeta smaragdinae DSM 11293 9490116 YP_003803732.1 CDS Spirs_2016 NC_014364.1 2165422 2166030 D COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR003583:IPR013849:IPR000445:IPR000085; KEGG: tde:TDE1863 Holliday junction DNA helicase RuvA; PFAM: DNA recombination protein RuvA domain I; helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding class 1; SPTR: Holliday junction DNA helicase RuvA; TIGRFAM: Holliday junction DNA helicase RuvA; PFAM: RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, Ruvsubunit alpha; Holliday junction DNA helicase RuvA 2165422..2166030 Spirochaeta smaragdinae DSM 11293 9490117 YP_003803733.1 CDS Spirs_2017 NC_014364.1 2166030 2167076 D COGs: COG2255 Holliday junction resolvasome helicase subunit; InterProIPR004605:IPR008823:IPR003593:IPR008824:IPR 003959; KEGG: tde:TDE1914 Holliday junction DNA helicase RuvB; PFAM: ATPase AAA central domain protein; Holliday junction DNA helicase RuvB domain; SMART: AAA ATPase; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: Holliday junction DNA helicase RuvB; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, Ruvsubunit beta; Holliday junction DNA helicase RuvB 2166030..2167076 Spirochaeta smaragdinae DSM 11293 9490118 YP_003803734.1 CDS Spirs_2018 NC_014364.1 2167051 2168091 D COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: tde:TDE2451 S-adenosylmethionine:tRNA ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; TIGRFAM:S-adenosylmethionine/tRNA-ribosyltransferas e-isomerase; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; S-adenosylmethionine/tRNA-ribosyltransferase- isomerase 2167051..2168091 Spirochaeta smaragdinae DSM 11293 9490119 YP_003803735.1 CDS Spirs_2019 NC_014364.1 2168085 2168690 R KEGG: tde:TDE2598 hypothetical protein; SPTR: uncharacterized protein; manually curated; hypothetical protein complement(2168085..2168690) Spirochaeta smaragdinae DSM 11293 9490120 YP_003803736.1 CDS Spirs_2020 NC_014364.1 2168698 2169318 R COGs: COG0125 Thymidylate kinase; InterPro IPR018094:IPR018095:IPR000062; KEGG: tde:TDE2599 thymidylate kinase; PFAM: thymidylate kinase; PRIAM: dTMP kinase; SPTR: Thymidylate kinase; TIGRFAM: thymidylate kinase; PFAM: Thymidylate kinase; TIGRFAM: thymidylate kinase; thymidylate kinase complement(2168698..2169318) Spirochaeta smaragdinae DSM 11293 9490121 YP_003803737.1 CDS Spirs_2021 NC_014364.1 2169489 2173772 D InterPro IPR007452; KEGG: tde:TDE2600 hypothetical protein; PFAM: protein of unknown function DUF490; SPTR: uncharacterized protein; PFAM: Family of unknown function (DUF490); hypothetical protein 2169489..2173772 Spirochaeta smaragdinae DSM 11293 9490122 YP_003803738.1 CDS Spirs_2022 NC_014364.1 2173798 2176341 D COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: tde:TDE2601 surface antigen, PFAM: surface antigen (D15); surface antigen variable number repeat protein; SPTR: Outer membrane protein 88; TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; outer membrane protein assembly complex, YaeT protein; outer membrane protein assembly complex, YaeT protein 2173798..2176341 Spirochaeta smaragdinae DSM 11293 9490123 YP_003803739.1 CDS Spirs_2023 NC_014364.1 2176351 2176914 D InterPro IPR005632; KEGG: tde:TDE2602 outer membrane protein, PFAM: outer membrane chaperone Skp (OmpH); SPTR: Outer membrane protein, ; PFAM: Outer membrane protein (OmpH-like); outer membrane chaperone Skp 2176351..2176914 Spirochaeta smaragdinae DSM 11293 9490124 YP_003803740.1 CDS Spirs_2024 NC_014364.1 2176948 2179515 D COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR005748:IPR007696:IPR000432:IPR007695:IPR 007860:IPR007861; KEGG: tde:TDE2603 DNA mismatch repair protein MutS; PFAM: MutS III domain protein; DNA mismatch repair protein MutS; MutS II domain protein; MutS IV domain protein; SMART: DNA mismatch repair protein MutS domain protein; MutS III domain protein; SPTR: DNA mismatch repair protein MutS; TIGRFAM: DNA mismatch repair protein MutS; PFAM: MutS family domain IV; MutS domain II; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS; DNA mismatch repair protein MutS 2176948..2179515 Spirochaeta smaragdinae DSM 11293 9490125 YP_003803741.1 CDS Spirs_2025 NC_014364.1 2179543 2180295 D COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: tde:TDE0972 ComF-related protein; PFAM: phosphoribosyltransferase; SPTR: ComF-related protein; PFAM: phosphoribosyl transferase domain; TIGRFAM: comF family protein; phosphoribosyltransferase 2179543..2180295 Spirochaeta smaragdinae DSM 11293 9490126 YP_003803742.1 CDS Spirs_2026 NC_014364.1 2180338 2180865 D InterPro IPR020790:IPR003728; KEGG: tde:TDE1108 hypothetical protein; PFAM: protein of unknown function DUF150; SPTR: uncharacterized protein; PFAM: Uncharacterised BCR, YhbC family COG0779; hypothetical protein 2180338..2180865 Spirochaeta smaragdinae DSM 11293 9490127 YP_003803743.1 CDS Spirs_2027 NC_014364.1 2180866 2182356 D COGs: COG0195 transcription elongation factor; InterPro IPR003029:IPR013735:IPR010213; KEGG: tde:TDE1107 transcription elongation factor NusA; PFAM: NusA domain protein; RNA binding S1 domain protein; SPTR: transcription elongation factor NusA; TIGRFAM: transcription termination factor NusA; PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA; transcription termination factor NusA 2180866..2182356 Spirochaeta smaragdinae DSM 11293 9490128 YP_003803744.1 CDS Spirs_2028 NC_014364.1 2182391 2184949 D COGs: COG0532 translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR006847:IPR000795:IPR004161:IPR 005225; KEGG: tde:TDE1106 translation initiation factor IF-2; PFAM: protein synthesis factor GTP-binding; translation initiation factor IF-2 domain protein; elongation factor Tu domain 2 protein; SPTR: translation initiation factor IF-2; TIGRFAM: translation initiation factor IF-2; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; translation-initiation factor 2; translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2; translation initiation factor IF-2 2182391..2184949 Spirochaeta smaragdinae DSM 11293 9490129 YP_003803745.1 CDS Spirs_2029 NC_014364.1 2184957 2185307 D COGs: COG0858 ribosome-binding factor A; InterPro IPR000238; KEGG: tde:TDE1105 ribosome-binding factor A; PFAM: ribosome-binding factor A; SPTR: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; PFAM: ribosome-binding factor A; TIGRFAM: ribosome-binding factor A; ribosome-binding factor A 2184957..2185307 Spirochaeta smaragdinae DSM 11293 9490130 YP_003803746.1 CDS Spirs_2030 NC_014364.1 2185309 2186208 D COGs: COG0130 Pseudouridine synthase; InterPro IPR002501:IPR014780; KEGG: bdu:BDU_811 tRNA pseudouridine 55 synthase; PFAM: pseudouridylate synthase TruB domain protein; SPTR: tRNA pseudouridine 55 synthase; TIGRFAM: tRNA pseudouridine synthase B; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase; tRNA pseudouridine synthase B 2185309..2186208 Spirochaeta smaragdinae DSM 11293 9490131 YP_003803747.1 CDS Spirs_2031 NC_014364.1 2186218 2187015 D COGs: COG0196 FAD synthase; InterPro IPR015864; KEGG: tpp:TPASS_0888 riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; SPTR: riboflavin kinase/FMN adenylyltransferase; PFAM: FAD synthetase; FAD synthetase 2186218..2187015 Spirochaeta smaragdinae DSM 11293 9490132 YP_003803748.1 CDS Spirs_2032 NC_014364.1 2187025 2187291 D COGs: COG0184 ribosomal protein S15P/S13E; InterPro IPR000589:IPR005290; KEGG: cwo:Cwoe_3228 ribosomal protein S15; PFAM: ribosomal protein S15; SPTR: 30S ribosomal protein S15P; TIGRFAM: ribosomal protein S15; PFAM: ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle; 30S ribosomal protein S15 2187025..2187291 Spirochaeta smaragdinae DSM 11293 9490133 YP_003803749.1 CDS Spirs_2033 NC_014364.1 2187309 2189402 D COGs: COG1185 polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterProIPR012162:IPR004087:IPR004088:IPR003029:IPR 001247:IPR015847:IPR015848:IPR018111; KEGG: tde:TDE1041 polynucleotide phosphorylase/polyadenylase; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; polynucleotide phosphorylase, phosphorolytic RNA-binding; K Homology, type 1, subgroup; RNA binding S1 domain protein; PRIAM: polyribonucleotide nucleotidyltransferase; SMART: KH domain protein; SPTR: polyribonucleotide nucleotidyltransferase; TIGRFAM: polyribonucleotide nucleotidyltransferase; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; polyribonucleotide nucleotidyltransferase, RNA binding domain; 3' exoribonuclease family, domain 2; TIGRFAM: polyribonucleotide nucleotidyltransferase; polyribonucleotide nucleotidyltransferase 2187309..2189402 Spirochaeta smaragdinae DSM 11293 9490134 YP_003803750.1 CDS Spirs_2034 NC_014364.1 2189436 2189873 D COGs: COG0756 dUTPase; InterPro IPR008180:IPR008181; KEGG: pla:Plav_3655 deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: deoxyUTP pyrophosphatase; PRIAM: dUTP diphosphatase; SPTR: deoxyuridine 5'-triphosphate nucleotidohydrolase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut); deoxyuridine 5'-triphosphate nucleotidohydrolase Dut 2189436..2189873 Spirochaeta smaragdinae DSM 11293 9490135 YP_003803751.1 CDS Spirs_2035 NC_014364.1 2189870 2191015 D COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1043 hypothetical protein; PFAM: permease YjgP/YjgQ family protein; SPTR: membrane protein, ; PFAM: Predicted permease YjgP/YjgQ family; permease YjgP/YjgQ family protein 2189870..2191015 Spirochaeta smaragdinae DSM 11293 9490136 YP_003803752.1 CDS Spirs_2036 NC_014364.1 2191012 2192094 D COGs: COG0795 permease; InterPro IPR005495; KEGG: tde:TDE1044 hypothetical protein; PFAM: permease YjgP/YjgQ family protein; SPTR: membrane protein, ; PFAM: Predicted permease YjgP/YjgQ family; permease YjgP/YjgQ family protein 2191012..2192094 Spirochaeta smaragdinae DSM 11293 9490137 YP_003803753.1 CDS Spirs_2037 NC_014364.1 2192112 2193236 D COGs: COG0343 queuine/archaeosine tRNA-ribosyltransferase; InterPro IPR004803:IPR002616; KEGG: bhr:BH0809 queuine tRNA-ribosyltransferase; PFAM: queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: queuine tRNA-ribosyltransferase; TIGRFAM: queuine tRNA-ribosyltransferase; tRNA-guanine transglycosylase, various specificities; PFAM: queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming; queuine tRNA-ribosyltransferase 2192112..2193236 Spirochaeta smaragdinae DSM 11293 9490138 YP_003803754.1 CDS Spirs_2038 NC_014364.1 2193243 2194829 D COGs: COG0728 membrane protein virulence factor; InterPro IPR004268; KEGG: bbz:BbuZS7_0840 integral membrane protein MviN; PFAM: virulence factor MVIN family protein; SPTR: integral membrane protein MviN; TIGRFAM: integral membrane protein MviN; PFAM: MviN-like protein; TIGRFAM: integral membrane protein MviN; integral membrane protein MviN 2193243..2194829 Spirochaeta smaragdinae DSM 11293 9490139 YP_003803755.1 CDS Spirs_2039 NC_014364.1 2194826 2196208 D COGs: COG1413 FOG: HEAT repeat; InterPro IPR004155; KEGG: tde:TDE0437 heat repeat-containing PBS lyase; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: PBS lyase HEAT-like repeat domain protein; PFAM: PBS lyase HEAT-like repeat; HEAT repeat; PBS lyase HEAT domain-containing protein repeat-containing protein 2194826..2196208 Spirochaeta smaragdinae DSM 11293 9490140 YP_003803756.1 CDS Spirs_2040 NC_014364.1 2196249 2198249 R InterPro IPR002035; KEGG: tpp:TPASS_0020 protein 76K; SMART: von Willebrand factor A; SPTR: 76K protein; von Willebrand factor A complement(2196249..2198249) Spirochaeta smaragdinae DSM 11293 9490141 YP_003803757.1 CDS Spirs_2041 NC_014364.1 2198315 2200999 R COGs: COG1747 Uncharacterized N-terminal domain of the transcription elongation factor GreA; InterPro IPR013026:IPR001437:IPR006359; KEGG: tde:TDE2695 transcript cleavage factor/unknown domain fusion protein; PFAM: transcription elongation factor GreA/GreB domain protein; SPTR: transcription elongation factor; TIGRFAM: transcription elongation factor GreA; PFAM: domain; transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA; transcription elongation factor GreA complement(2198315..2200999) Spirochaeta smaragdinae DSM 11293 9490142 YP_003803758.1 CDS Spirs_2042 NC_014364.1 2201018 2201980 R InterPro IPR019734:IPR013026:IPR013105; KEGG: tpp:TPASS_0017 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; hypothetical protein complement(2201018..2201980) Spirochaeta smaragdinae DSM 11293 9490143 YP_003803759.1 CDS Spirs_2043 NC_014364.1 2202134 2202925 D COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR016166:IPR002346; KEGG: cdl:CDR20291_2008 FAD-binding subunit of oxidoreductase; PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: Molybdopterin dehydrogenase, FAD-binding protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; molybdopterin dehydrogenase FAD-binding protein 2202134..2202925 Spirochaeta smaragdinae DSM 11293 9490144 YP_003803760.1 CDS Spirs_2044 NC_014364.1 2202922 2203377 D COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: cdl:CDR20291_2007 [2Fe-2S]-binding subunit of oxidoreductase; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: aldehyde oxidase and xanthine dehydrogenase domains protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein 2202922..2203377 Spirochaeta smaragdinae DSM 11293 9490145 YP_003803761.1 CDS Spirs_2045 NC_014364.1 2203370 2205703 D COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: taf:THA_1660 probable hypoxanthine oxidase XdhD; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: Probable hypoxanthine oxidase XdhD; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein 2203370..2205703 Spirochaeta smaragdinae DSM 11293 9490146 YP_003803762.1 CDS Spirs_2046 NC_014364.1 2205808 2206470 D COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: sat:SYN_01763 ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; PRIAM: ribulose-phosphate 3-epimerase; SPTR: ribulose-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase; ribulose-phosphate 3-epimerase 2205808..2206470 Spirochaeta smaragdinae DSM 11293 9490147 YP_003803763.1 CDS Spirs_2047 NC_014364.1 2206516 2207460 D InterPro IPR013026; KEGG: tde:TDE2596 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: tol-pal system protein YbgF; hypothetical protein 2206516..2207460 Spirochaeta smaragdinae DSM 11293 9490148 YP_003803764.1 CDS Spirs_2048 NC_014364.1 2207457 2208539 D KEGG: tde:TDE2595 hypothetical protein; SPTR: S-layer domain protein; hypothetical protein 2207457..2208539 Spirochaeta smaragdinae DSM 11293 9490149 YP_003803765.1 CDS Spirs_2049 NC_014364.1 2208552 2209646 D InterPro IPR019734:IPR013026:IPR001440; KEGG: tde:TDE2594 hypothetical protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: uncharacterized protein; hypothetical protein 2208552..2209646 Spirochaeta smaragdinae DSM 11293 9490150 YP_003803766.1 CDS Spirs_2050 NC_014364.1 2209643 2210092 D COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: taf:THA_1655 dtd D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; D-tyrosyl-tRNA(Tyr) deacylase 2209643..2210092 Spirochaeta smaragdinae DSM 11293 9490151 YP_003803767.1 CDS Spirs_2051 NC_014364.1 2210146 2211291 D COGs: COG0468 RecA/RadA recombinase; InterProIPR013765:IPR001553:IPR003593:IPR020584:IPR 020588:IPR020587; KEGG: tde:TDE0872 recombinase A; PFAM: RecA domain protein; SMART: ATPase AAA; SPTR: protein recA; TIGRFAM: recA protein; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA; recA protein 2210146..2211291 Spirochaeta smaragdinae DSM 11293 9490152 YP_003803768.1 CDS Spirs_2052 NC_014364.1 2211292 2212101 D COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: tde:TDE0873 hypothetical protein; PFAM: chromosome segregation and condensation protein ScpA; SPTR: ScpA/B protein; PFAM: ScpA/B protein; chromosome segregation and condensation protein ScpA 2211292..2212101 Spirochaeta smaragdinae DSM 11293 9490153 YP_003803769.1 CDS Spirs_2053 NC_014364.1 2212108 2212647 D COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: tde:TDE0874 transcriptional regulator, PFAM: chromosome segregation and condensation protein ScpB; SPTR: transcriptional regulator, ; TIGRFAM: segregation and condensation protein B; PFAM: transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B; chromosome segregation and condensation protein ScpB 2212108..2212647 Spirochaeta smaragdinae DSM 11293 9490154 YP_003803770.1 CDS Spirs_2054 NC_014364.1 2212640 2213395 D COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR018496:IPR006145:IPR000748; KEGG: tde:TDE0875 ribosomal large subunit pseudouridine synthase B; PFAM: RNA-binding S4 domain protein; pseudouridine synthase; SMART: RNA-binding S4 domain protein; SPTR: ribosomal large subunit pseudouridine synthase B; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase family; RNA-binding S4 domain-containing protein 2212640..2213395 Spirochaeta smaragdinae DSM 11293 9490155 YP_003803771.1 CDS Spirs_2055 NC_014364.1 2213392 2214066 D COGs: COG0283 Cytidylate kinase; InterPro IPR003136:IPR011994; KEGG: tde:TDE2080 cytidylate kinase/ribosomal protein S1; PFAM: cytidylate kinase region; SPTR: Cytidylate kinase/ribosomal protein S1; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; cytidylate kinase 2213392..2214066 Spirochaeta smaragdinae DSM 11293 9490156 YP_003803772.1 CDS Spirs_2056 NC_014364.1 2214050 2215765 D COGs: COG0539 ribosomal protein S1; InterPro IPR000110:IPR003029:IPR018032; KEGG: tde:TDE2080 cytidylate kinase/ribosomal protein S1; PFAM: RNA binding S1 domain protein; SPTR: Cytidylate kinase/ribosomal protein S1; TIGRFAM: ribosomal protein S1; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1; 30S ribosomal protein S1 2214050..2215765 Spirochaeta smaragdinae DSM 11293 9490157 YP_003803773.1 CDS Spirs_2057 NC_014364.1 2215771 2217273 D COGs: COG3604 transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR020441:IPR003018:IPR003593:IPR002078:IPR 002197; KEGG: tde:TDE2079 sigma-54 dependent transcriptional regulator, PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; ATPase AAA; SPTR: Sigma-54 dependent transcriptional regulator, ; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Fis family transcriptional regulator 2215771..2217273 Spirochaeta smaragdinae DSM 11293 9490158 YP_003803774.1 CDS Spirs_2058 NC_014364.1 2217298 2217981 D InterPro IPR019734:IPR013026:IPR001440; KEGG: tde:TDE2078 hypothetical protein; PFAM: hypothetical protein; SPTR: TPR domain protein; hypothetical protein 2217298..2217981 Spirochaeta smaragdinae DSM 11293 9490159 YP_003803775.1 CDS Spirs_2059 NC_014364.1 2218001 2220382 D COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001054:IPR007890; KEGG: lic:LIC10862 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; adenylate/guanylate cyclase with Chase sensor 2218001..2220382 Spirochaeta smaragdinae DSM 11293 9490160 YP_003803776.1 CDS Spirs_2060 NC_014364.1 2220357 2221163 D KEGG: cgb:cg0060 D-alanyl-D-alanine carboxypeptidase; SPTR: cell division protein FtsI/penicillin-binding protein 2; hypothetical protein 2220357..2221163 Spirochaeta smaragdinae DSM 11293 9490161 YP_003803777.1 CDS Spirs_2061 NC_014364.1 2221214 2221519 D KEGG: lbf:LBF_0627 chloride channel protein; SPTR: voltage-gated ClC-type chloride channel eriC; membrane protein; hypothetical protein 2221214..2221519 Spirochaeta smaragdinae DSM 11293 9490162 YP_003803778.1 CDS Spirs_2062 NC_014364.1 2221534 2223159 D COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR018062:IPR000005; KEGG: cpy:Cphy_3282 two component AraC family transcriptional regulator; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2221534..2223159 Spirochaeta smaragdinae DSM 11293 9490163 YP_003803779.1 CDS Spirs_2063 NC_014364.1 2223152 2224222 D COGs: COG3275 regulator of cell autolysis; InterPro IPR004358:IPR005467:IPR010559:IPR003594; KEGG: cpy:Cphy_3281 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: two-component sensor kinase YesM; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase LytS 2223152..2224222 Spirochaeta smaragdinae DSM 11293 9490164 YP_003803780.1 CDS Spirs_2064 NC_014364.1 2224212 2225684 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439; KEGG: ara:Arad_9424 sugar ABC transporter; PRIAM: sugar ATP transporter ATPase; SMART: ATPase AAA; SPTR: ABC transporter; sugar ATP transporter ATPase 2224212..2225684 Spirochaeta smaragdinae DSM 11293 9490165 YP_003803781.1 CDS Spirs_2065 NC_014364.1 2225681 2226634 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: dfe:Dfer_3165 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 2225681..2226634 Spirochaeta smaragdinae DSM 11293 9490166 YP_003803782.1 CDS Spirs_2066 NC_014364.1 2226746 2228272 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR017871:IPR003439; KEGG: bha:BH2322 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: Sugar ABC transporter; PFAM: ABC transporter; ABC transporter 2226746..2228272 Spirochaeta smaragdinae DSM 11293 9490167 YP_003803783.1 CDS Spirs_2067 NC_014364.1 2228259 2229221 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR007382:IPR001851; KEGG: dfe:Dfer_3165 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator 2228259..2229221 Spirochaeta smaragdinae DSM 11293 9490168 YP_003803784.1 CDS Spirs_2068 NC_014364.1 2229261 2230202 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: cce:Ccel_1642 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Possible periplasmic binding protein/LacI transcriptional regulator; PFAM: family; LacI family transcriptional regulator 2229261..2230202 Spirochaeta smaragdinae DSM 11293 9490169 YP_003803785.1 CDS Spirs_2069 NC_014364.1 2230621 2231487 D COGs: COG3956 protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518:IPR011551; KEGG: afl:Aflv_0051 tetrapyrrole methyltransferase domain fused to a MazG family NTP pyrophosphatase domain; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: Tetrapyrrole methyltransferase domain fused to a MazG family NTP pyrophosphatase domain; TIGRFAM: MazG family protein; manually curated; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein; MazG family protein 2230621..2231487 Spirochaeta smaragdinae DSM 11293 9490170 YP_003803786.1 CDS Spirs_2070 NC_014364.1 2231503 2234040 R COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006638:IPR007197:IPR018768; KEGG: gem:GM21_0141 radical SAM domain protein; PFAM: radical SAM protein; protein of unknown function DUF2344; SMART: Elongator protein 3/MiaB/NifB; SPTR: radical SAM domain protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); radical SAM superfamily; radical SAM protein complement(2231503..2234040) Spirochaeta smaragdinae DSM 11293 9490171 YP_003803787.1 CDS Spirs_2071 NC_014364.1 2234052 2235365 R COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR018365:IPR001182:IPR011923; KEGG: tde:TDE1353 rod shape-determining protein RodA; PFAM: cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; TIGRFAM: rod shape-determining protein RodA; rod shape-determining protein RodA complement(2234052..2235365) Spirochaeta smaragdinae DSM 11293 9490172 YP_003803788.1 CDS Spirs_2072 NC_014364.1 2235367 2237235 R COGs: COG0768 cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR017790; KEGG: tpa:TP0500 penicillin-binding protein (pbp-1); PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PRIAM: peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein (Pbp-1); TIGRFAM: penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding protein dimerisation domain; TIGRFAM: penicillin-binding protein 2; penicillin-binding protein 2 complement(2235367..2237235) Spirochaeta smaragdinae DSM 11293 9490173 YP_003803789.1 CDS Spirs_2073 NC_014364.1 2237235 2237741 R InterPro IPR007227; KEGG: tpp:TPASS_0499 rod shape-determining protein; SPTR: Rod shape-determining protein (MreD); TIGRFAM: rod shape-determining protein MreD; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD; rod shape-determining protein MreD complement(2237235..2237741) Spirochaeta smaragdinae DSM 11293 9490174 YP_003803790.1 CDS Spirs_2074 NC_014364.1 2237738 2238592 R COGs: COG1792 cell shape-determining protein; InterPro IPR007221:IPR005223; KEGG: tde:TDE1350 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC; rod shape-determining protein MreC complement(2237738..2238592) Spirochaeta smaragdinae DSM 11293 9490175 YP_003803791.1 CDS Spirs_2075 NC_014364.1 2238610 2239653 R COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: tde:TDE1349 rod shape-determining protein MreB; PFAM: cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family; MreB/Mrl family cell shape determining protein complement(2238610..2239653) Spirochaeta smaragdinae DSM 11293 9490176 YP_003803792.1 CDS Spirs_2076 NC_014364.1 2239677 2240666 R InterPro IPR019734:IPR013026:IPR013105:IPR001440; KEGG: tde:TDE1348 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; manually curated; PFAM: Tetratricopeptide repeat; hypothetical protein complement(2239677..2240666) Spirochaeta smaragdinae DSM 11293 9490177 YP_003803793.1 CDS Spirs_2077 NC_014364.1 2241048 2241845 R COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: tpp:TPASS_0494 hypothetical protein; PFAM: protein of unknown function DUF164; SPTR: uncharacterized protein; PFAM: zinc ribbon domain; hypothetical protein complement(2241048..2241845) Spirochaeta smaragdinae DSM 11293 9490179 YP_003803794.1 CDS Spirs_2078 NC_014364.1 2241858 2243696 R COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR000943:IPR007127:IPR009042:IPR007627:IPR 007624:IPR007630:IPR014284:IPR012760; KEGG: tde:TDE1346 RNA polymerase sigma factor RpoD; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 1.2; sigma-70 1.1 domain protein; sigma-70 region 4 domain protein; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain; RpoD subfamily RNA polymerase sigma-70 subunit complement(2241858..2243696) Spirochaeta smaragdinae DSM 11293 9490180 YP_003803795.1 CDS Spirs_2079 NC_014364.1 2243693 2245474 R COGs: COG0358 DNA primase; InterProIPR002694:IPR006154:IPR013264:IPR006171:IPR 006295; KEGG: tde:TDE1345 DNA primase; PFAM: DNA primase catalytic core domain; zinc finger CHC2-family protein; TOPRIM domain protein; SMART: zinc finger CHC2-family protein; Toprim sub domain protein; SPTR: DNA primase; TIGRFAM: DNA primase; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core; DNA primase complement(2243693..2245474) Spirochaeta smaragdinae DSM 11293 9490181 YP_003803796.1 CDS Spirs_2080 NC_014364.1 2245478 2246521 R COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: bre:BRE_716 hypothetical protein; PFAM: aminodeoxychorismate lyase; SPTR: Aminodeoxychorismate lyase; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein TIGR00247; aminodeoxychorismate lyase complement(2245478..2246521) Spirochaeta smaragdinae DSM 11293 9490182 YP_003803797.1 CDS Spirs_2081 NC_014364.1 2246524 2250756 R COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE2028 OmpA family protein; PFAM: OmpA/MotB domain protein; SPTR: OmpA family protein; PFAM: OmpA family; OmpA/MotB domain-containing protein complement(2246524..2250756) Spirochaeta smaragdinae DSM 11293 9490183 YP_003803798.1 CDS Spirs_2082 NC_014364.1 2250784 2250981 R KEGG: aae:aq_1335 nucleotide sugar epimerase; SPTR: nucleotide sugar epimerase; hypothetical protein complement(2250784..2250981) Spirochaeta smaragdinae DSM 11293 9490184 YP_003803799.1 CDS Spirs_2083 NC_014364.1 2250978 2251919 R COGs: COG1235 metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: tde:TDE1541 metallo-beta-lactamase family protein; SPTR: metallo-beta-lactamase family protein; PFAM: metallo-beta-lactamase superfamily; metallo-beta-lactamase family protein complement(2250978..2251919) Spirochaeta smaragdinae DSM 11293 9490185 YP_003803800.1 CDS Spirs_2084 NC_014364.1 2251922 2252416 R InterPro IPR005358; KEGG: tde:TDE1540 hypothetical protein; PFAM: protein of unknown function UPF0153; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family (UPF0153); hypothetical protein complement(2251922..2252416) Spirochaeta smaragdinae DSM 11293 9490186 YP_003803801.1 CDS Spirs_2085 NC_014364.1 2253076 2253438 R COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779:IPR004675; KEGG: mba:Mbar_A2644 hypothetical protein; PFAM: carboxymuconolactone decarboxylase; SPTR: uncharacterized protein; TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: carboxymuconolactone decarboxylase family; TIGRFAM: alkylhydroperoxidase AhpD family core domain; alkylhydroperoxidase like protein complement(2253076..2253438) Spirochaeta smaragdinae DSM 11293 9490189 YP_003803802.1 CDS Spirs_2087 NC_014364.1 2253980 2254861 R InterPro IPR007530; KEGG: bcx:BCA_2025 aminoglycoside 6-adenylyltransferase; PFAM: adenylyltransferase; SPTR: Streptomycin adenylyltransferase; PFAM: Streptomycin adenylyltransferase; adenylyltransferase complement(2253980..2254861) Spirochaeta smaragdinae DSM 11293 9490191 YP_003803803.1 CDS Spirs_2088 NC_014364.1 2255133 2255468 D InterPro IPR002514; KEGG: pvi:Cvib_1307 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase; transposase IS3/IS911 family protein 2255133..2255468 Spirochaeta smaragdinae DSM 11293 9490192 YP_003803804.1 CDS Spirs_2089 NC_014364.1 2255461 2256297 D COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: maq:Maqu_0236 integrase catalytic subunit; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain; Integrase catalytic subunit 2255461..2256297 Spirochaeta smaragdinae DSM 11293 9490193 YP_003803805.1 CDS Spirs_2090 NC_014364.1 2256559 2257386 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: pde:Pden_1049 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2256559..2257386) Spirochaeta smaragdinae DSM 11293 9490194 YP_003803806.1 CDS Spirs_2091 NC_014364.1 2257389 2258285 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: rfr:Rfer_0953 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2257389..2258285) Spirochaeta smaragdinae DSM 11293 9490195 YP_003803807.1 CDS Spirs_2092 NC_014364.1 2258344 2259642 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: bja:bll2731 ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: carbohydrate ABC transporter substrate-binding protein, CUT1 family; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2258344..2259642) Spirochaeta smaragdinae DSM 11293 9490196 YP_003803808.1 CDS Spirs_2093 NC_014364.1 2259669 2260442 R COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: mes:Meso_4473 amidohydrolase 2; PFAM: amidohydrolase 2; SPTR: Amidohydrolase 2; PFAM: Amidohydrolase; amidohydrolase 2 complement(2259669..2260442) Spirochaeta smaragdinae DSM 11293 9490197 YP_003803809.1 CDS Spirs_2094 NC_014364.1 2260435 2261235 R COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: mes:Meso_4473 amidohydrolase 2; PFAM: amidohydrolase 2; SPTR: Amidohydrolase 2; PFAM: Amidohydrolase; amidohydrolase 2 complement(2260435..2261235) Spirochaeta smaragdinae DSM 11293 9490198 YP_003803810.1 CDS Spirs_2095 NC_014364.1 2261433 2262569 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ttr:Tter_2656 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein 2261433..2262569 Spirochaeta smaragdinae DSM 11293 9490199 YP_003803811.1 CDS Spirs_2096 NC_014364.1 2262583 2264865 D COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR001764:IPR019800:IPR002772; KEGG: cth:Cthe_1256 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 3 domain protein; PRIAM: beta-glucosidase; SPTR: glycoside hydrolase family 3 domain protein; PFAM: glycosyl hydrolase family 3 C terminal domain; glycosyl hydrolase family 3 N terminal domain; beta-glucosidase 2262583..2264865 Spirochaeta smaragdinae DSM 11293 9490200 YP_003803812.1 CDS Spirs_2097 NC_014364.1 2264994 2265206 R COGs: COG3585 Molybdopterin-binding protein; InterPro IPR005116:IPR004606; KEGG: mpl:Mpal_1586 TOBE domain protein; PFAM: TOBE domain protein; SPTR: TOBE domain protein; PFAM: TOBE domain; TIGRFAM: molybdenum-pterin binding domain; TOBE domain-containing protein complement(2264994..2265206) Spirochaeta smaragdinae DSM 11293 9490201 YP_003803813.1 CDS Spirs_2099 NC_014364.1 2265838 2266086 D KEGG: fjo:Fjoh_4853 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2265838..2266086 Spirochaeta smaragdinae DSM 11293 9490203 YP_003803814.1 CDS Spirs_2100 NC_014364.1 2266320 2266688 D InterPro IPR013229; KEGG: lch:Lcho_3855 hypothetical protein; PFAM: PEGA domain protein; SPTR: uncharacterized protein; PFAM: PEGA domain; PEGA domain-containing protein 2266320..2266688 Spirochaeta smaragdinae DSM 11293 9490204 YP_003803815.1 CDS Spirs_2101 NC_014364.1 2266692 2268146 D KEGG: tdn:Suden_1998 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2266692..2268146 Spirochaeta smaragdinae DSM 11293 9490205 YP_003803816.1 CDS Spirs_2102 NC_014364.1 2268249 2268857 R KEGG: amt:Amet_4707 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2268249..2268857) Spirochaeta smaragdinae DSM 11293 9490206 YP_003803817.1 CDS Spirs_2103 NC_014364.1 2268874 2269572 R InterPro IPR001763; KEGG: amt:Amet_4706 rhodanese domain-containing protein; SPTR: uncharacterized protein; hypothetical protein complement(2268874..2269572) Spirochaeta smaragdinae DSM 11293 9490207 YP_003803818.1 CDS Spirs_2104 NC_014364.1 2269806 2270384 R KEGG: dvi:Dvir_GJ19754 GJ19754 gene product from transcript GJ19754-RA; SPTR: uncharacterized protein; hypothetical protein complement(2269806..2270384) Spirochaeta smaragdinae DSM 11293 9490208 YP_003803819.1 CDS Spirs_2105 NC_014364.1 2270579 2271487 R InterPro IPR010916:IPR000620; KEGG: oan:Oant_1578 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family; hypothetical protein complement(2270579..2271487) Spirochaeta smaragdinae DSM 11293 9490209 YP_003803820.1 CDS Spirs_2106 NC_014364.1 2271687 2272757 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR003660:IPR003661:IPR003594:IPR 005467; KEGG: cpy:Cphy_1862 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Signal transduction histidine kinase; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase complement(2271687..2272757) Spirochaeta smaragdinae DSM 11293 9490210 YP_003803821.1 CDS Spirs_2107 NC_014364.1 2272745 2273428 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: cpy:Cphy_1861 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator complement(2272745..2273428) Spirochaeta smaragdinae DSM 11293 9490211 YP_003803822.1 CDS Spirs_2108 NC_014364.1 2273562 2275301 D COGs: COG0443 Molecular chaperone; InterPro IPR012725:IPR001023:IPR018181:IPR013126; KEGG: cth:Cthe_1322 molecular chaperone DnaK; PFAM: heat shock protein 70; SPTR: uncharacterized protein; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK; chaperone protein DnaK 2273562..2275301 Spirochaeta smaragdinae DSM 11293 9490212 YP_003803823.1 CDS Spirs_2109 NC_014364.1 2275311 2276132 D KEGG: cpy:Cphy_0207 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2275311..2276132 Spirochaeta smaragdinae DSM 11293 9490213 YP_003803824.1 CDS Spirs_2110 NC_014364.1 2276129 2276821 D COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR001623; KEGG: ere:EUBREC_2351 chaperone protein DnaJ; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: uncharacterized protein; PFAM: DnaJ domain; heat shock protein DnaJ domain-containing protein 2276129..2276821 Spirochaeta smaragdinae DSM 11293 9490214 YP_003803825.1 CDS Spirs_2111 NC_014364.1 2276831 2277247 D KEGG: cpy:Cphy_3541 Zn-finger containing protein; SPTR: uncharacterized protein; Zn-finger containing protein 2276831..2277247 Spirochaeta smaragdinae DSM 11293 9490215 YP_003803826.1 CDS Spirs_2112 NC_014364.1 2277382 2277774 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789; KEGG: lbf:LBF_2370 signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: two-component response regulator; PFAM: Response regulator receiver domain; response regulator receiver protein 2277382..2277774 Spirochaeta smaragdinae DSM 11293 9490216 YP_003803827.1 CDS Spirs_2113 NC_014364.1 2277833 2279542 R COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR011495; KEGG: cya:CYA_2886 sensory box histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; SMART: ATP-binding region ATPase domain protein; SPTR: sensory box histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase complement(2277833..2279542) Spirochaeta smaragdinae DSM 11293 9490217 YP_003803828.1 CDS Spirs_2114 NC_014364.1 2279588 2280421 R COGs: COG2746 Aminoglycoside N3'-acetyltransferase; InterPro IPR003679; KEGG: gym:GYMC10_5436 aminoglycoside N(3')-acetyltransferase; PFAM: aminoglycoside 3-N-acetyltransferase; PRIAM: Aminoglycoside N(3')-acetyltransferase; SPTR: Aminoglycoside N(3')-acetyltransferase; PFAM: Aminoglycoside 3-N-acetyltransferase; Aminoglycoside N(3')-acetyltransferase complement(2279588..2280421) Spirochaeta smaragdinae DSM 11293 9490218 YP_003803829.1 CDS Spirs_2115 NC_014364.1 2280541 2281413 D InterPro IPR000835:IPR000182; KEGG: mab:MAB_1138c MarR family transcriptional regulator; PFAM: GCN5-related N-acetyltransferase; regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family; acetyltransferase (GNAT) family; MarR family transcriptional regulator 2280541..2281413 Spirochaeta smaragdinae DSM 11293 9490219 YP_003803830.1 CDS Spirs_2116 NC_014364.1 2281484 2282323 D InterPro IPR003675; KEGG: cbh:CLC_0981 CAAX amino terminal protease family protein; PFAM: hypothetical protein; SPTR: CAAX amino terminal protease family protein; PFAM: CAAX amino terminal protease family; hypothetical protein 2281484..2282323 Spirochaeta smaragdinae DSM 11293 9490220 YP_003803831.1 CDS Spirs_2117 NC_014364.1 2282346 2283263 R COGs: COG3238 conserved hypothetical protein; InterPro IPR006750; KEGG: cbi:CLJ_B3664 hypothetical protein; PFAM: protein of unknown function DUF606; SPTR: membrane protein; PFAM: protein of unknown function, DUF606; hypothetical protein complement(2282346..2283263) Spirochaeta smaragdinae DSM 11293 9490221 YP_003803832.1 CDS Spirs_2118 NC_014364.1 2283356 2283736 R COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cbl:CLK_2799 transcriptional regulator; PFAM: protein of unknown function UPF0074; SPTR: transcriptional regulator; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator); BadM/Rrf2 family transcriptional regulator complement(2283356..2283736) Spirochaeta smaragdinae DSM 11293 9490222 YP_003803833.1 CDS Spirs_2119 NC_014364.1 2283836 2285716 R COGs: COG4564 Signal transduction histidine kinase; InterPro IPR004089:IPR003660:IPR013163; KEGG: dsa:Desal_3375 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; Cache type 2 domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(2283836..2285716) Spirochaeta smaragdinae DSM 11293 9490223 YP_003803834.1 CDS Spirs_2120 NC_014364.1 2285834 2287399 R COGs: COG3525 N-acetyl-beta-hexosaminidase; InterPro IPR001540:IPR015883; KEGG: coc:Coch_1350 beta-N-acetylhexosaminidase; PFAM: glycoside hydrolase, family 20, catalytic core; PRIAM: beta-N-acetylhexosaminidase; SPTR: beta-hexosaminidase; PFAM: glycosyl hydrolase family 20, catalytic domain; beta-N-acetylhexosaminidase complement(2285834..2287399) Spirochaeta smaragdinae DSM 11293 9490224 YP_003803835.1 CDS Spirs_2121 NC_014364.1 2287412 2288242 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_13120 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2287412..2288242) Spirochaeta smaragdinae DSM 11293 9490225 YP_003803836.1 CDS Spirs_2122 NC_014364.1 2288255 2289142 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hor:Hore_13130 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2288255..2289142) Spirochaeta smaragdinae DSM 11293 9490226 YP_003803837.1 CDS Spirs_2123 NC_014364.1 2289203 2290522 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_0454 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2289203..2290522) Spirochaeta smaragdinae DSM 11293 9490227 YP_003803838.1 CDS Spirs_2124 NC_014364.1 2290579 2291745 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: xylR; xylose repressor; PFAM: ROK family protein; SPTR: Xylose repressor; PFAM: ROK family; ROK family protein complement(2290579..2291745) Spirochaeta smaragdinae DSM 11293 9490228 YP_003803839.1 CDS Spirs_2125 NC_014364.1 2291819 2292421 R COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR003095:IPR001623; KEGG: mgm:Mmc1_0565 heat shock protein DnaJ domain-containing protein; PFAM: heat shock protein DnaJ domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: heat shock protein DnaJ domain protein; PFAM: DnaJ domain; DNA-J related protein; heat shock protein DnaJ domain-containing protein complement(2291819..2292421) Spirochaeta smaragdinae DSM 11293 9490229 YP_003803840.1 CDS Spirs_2126 NC_014364.1 2292486 2293172 D COGs: COG2454 conserved hypothetical protein; InterPro IPR007368; KEGG: cac:CAC1606 hypothetical protein; PFAM: protein of unknown function DUF434; SPTR: Uncharacterized conserved protein; PFAM: protein of unknown function (DUF434); hypothetical protein 2292486..2293172 Spirochaeta smaragdinae DSM 11293 9490230 YP_003803841.1 CDS Spirs_2127 NC_014364.1 2293165 2294157 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: lbf:LBF_1699 oxidoreductase, NAD-binding; PFAM: oxidoreductase domain protein; SPTR: glucose-fructose oxidoreductase; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 2293165..2294157 Spirochaeta smaragdinae DSM 11293 9490231 YP_003803842.1 CDS Spirs_2128 NC_014364.1 2294164 2295003 D KEGG: rrs:RoseRS_2062 hypothetical protein; SPTR: transcriptional regulator; hypothetical protein 2294164..2295003 Spirochaeta smaragdinae DSM 11293 9490232 YP_003803843.1 CDS Spirs_2129 NC_014364.1 2294987 2295319 R KEGG: smd:Smed_2224 L-threonine 3-dehydrogenase; SPTR: L-threonine 3-dehydrogenase; hypothetical protein complement(2294987..2295319) Spirochaeta smaragdinae DSM 11293 9490233 YP_003803844.1 CDS Spirs_2130 NC_014364.1 2295375 2295944 R COGs: COG1611 Rossmann fold nucleotide-binding protein; InterPro IPR005269; KEGG: mca:MCA2182 decarboxylase family protein; PFAM: conserved hypothetical protein; SPTR: Decarboxylase family protein; PFAM: Possible lysine decarboxylase; TIGRFAM: conserved hypothetical protein, DprA/Smf-related, family 2; hypothetical protein complement(2295375..2295944) Spirochaeta smaragdinae DSM 11293 9490234 YP_003803845.1 CDS Spirs_2131 NC_014364.1 2295958 2296941 R COGs: COG0167 dihydroorotate dehydrogenase; InterPro IPR012135; KEGG: pvi:Cvib_1724 dihydroorotate dehydrogenase 2; PFAM: dihydroorotate oxidase; SPTR: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; dihydroorotate oxidase complement(2295958..2296941) Spirochaeta smaragdinae DSM 11293 9490235 YP_003803846.1 CDS Spirs_2132 NC_014364.1 2297080 2298540 R COGs: COG1003 glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR020580; KEGG: chy:CHY_0492 glycine dehydrogenase subunit 2; PFAM: glycine cleavage system P-protein-like; SPTR: glycine dehydrogenase (Decarboxylating), subunit 2; PFAM: glycine cleavage system P-protein; glycine cleavage system P-protein complement(2297080..2298540) Spirochaeta smaragdinae DSM 11293 9490236 YP_003803847.1 CDS Spirs_2133 NC_014364.1 2298540 2299883 R COGs: COG0403 glycine cleavage system protein P (pyridoxal-binding) N-terminal domain; InterPro IPR018366:IPR020580; KEGG: gtn:GTNG_2363 glycine dehydrogenase subunit 1; PFAM: glycine cleavage system P-protein-like; PRIAM: glycine dehydrogenase (decarboxylating); SPTR: glycine dehydrogenase (Decarboxylating); PFAM: glycine cleavage system P-protein; glycine dehydrogenase complement(2298540..2299883) Spirochaeta smaragdinae DSM 11293 9490237 YP_003803848.1 CDS Spirs_2134 NC_014364.1 2299891 2300274 R COGs: COG0509 glycine cleavage system protein H (lipoate-binding); InterPro IPR002930:IPR003016:IPR017453; KEGG: tna:CTN_0473 glycine cleavage system protein H; PFAM: glycine cleavage H-protein; SPTR: hydrogen carrier protein; TIGRFAM: glycine cleavage system protein H; PFAM: glycine cleavage H-protein; TIGRFAM: glycine cleavage system protein H; glycine cleavage system protein H complement(2299891..2300274) Spirochaeta smaragdinae DSM 11293 9490238 YP_003803849.1 CDS Spirs_2135 NC_014364.1 2300297 2301424 R COGs: COG0404 glycine cleavage system protein T (aminomethyltransferase); InterPro IPR006223:IPR006222:IPR013977; KEGG: gwc:GWCH70_2361 glycine cleavage system protein T; PFAM: glycine cleavage T protein (aminomethyl transferase); glycine cleavage T-protein barrel; SPTR: Aminomethyltransferase; TIGRFAM: glycine cleavage system protein T; PFAM: glycine cleavage T-protein C-terminal barrel domain; Aminomethyltransferase folate-binding domain; TIGRFAM: glycine cleavage system protein T; glycine cleavage system protein T complement(2300297..2301424) Spirochaeta smaragdinae DSM 11293 9490239 YP_003803850.1 CDS Spirs_2136 NC_014364.1 2301436 2301885 R COGs: COG1522 transcriptional regulators; InterPro IPR019888:IPR000485:IPR019887; KEGG: dat:HRM2_25020 HTH-type transcriptional regulator; PFAM: transcription regulator, AsnC-type-like; SMART: transcription regulator, AsnC-type; SPTR: HTH-type transcriptional regulator; AsnC family transcriptional regulator complement(2301436..2301885) Spirochaeta smaragdinae DSM 11293 9490240 YP_003803851.1 CDS Spirs_2137 NC_014364.1 2301892 2302977 R COGs: COG1932 phosphoserine aminotransferase; InterPro IPR000192:IPR003248; KEGG: gyc:GYMC61_1454 phosphoserine aminotransferase; PFAM: aminotransferase class V; PRIAM: phosphoserine transaminase; SPTR: phosphoserine aminotransferase; TIGRFAM: phosphoserine aminotransferase; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase; phosphoserine aminotransferase complement(2301892..2302977) Spirochaeta smaragdinae DSM 11293 9490241 YP_003803852.1 CDS Spirs_2138 NC_014364.1 2302974 2303861 R COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: min:Minf_1255 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase complement(2302974..2303861) Spirochaeta smaragdinae DSM 11293 9490242 YP_003803853.1 CDS Spirs_2139 NC_014364.1 2304044 2304262 R InterPro IPR001911:IPR018278; KEGG: tde:TDE2473 30S ribosomal protein S21; PFAM: ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: ribosomal protein S21; PFAM: ribosomal protein S21; TIGRFAM: ribosomal protein S21; 30S ribosomal protein S21 complement(2304044..2304262) Spirochaeta smaragdinae DSM 11293 9490243 YP_003803854.1 CDS Spirs_2140 NC_014364.1 2304284 2305207 R COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tde:TDE2189 M23/M37 peptidase domain-containing protein; PFAM: peptidase M23; SPTR: M23/M37 peptidase domain protein; PFAM: peptidase family M23; peptidase M23 complement(2304284..2305207) Spirochaeta smaragdinae DSM 11293 9490244 YP_003803855.1 CDS Spirs_2141 NC_014364.1 2305204 2307324 R COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR001667:IPR003156:IPR004610; KEGG: tde:TDE2190 single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: DHHA1 domain; DHH family; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; single-stranded-DNA-specific exonuclease RecJ complement(2305204..2307324) Spirochaeta smaragdinae DSM 11293 9490245 YP_003803856.1 CDS Spirs_2142 NC_014364.1 2307305 2307829 R COGs: COG1514 2'-5' RNA ligase; InterPro IPR014051:IPR004175; KEGG: hor:Hore_11900 2'-5' RNA ligase; PFAM: phosphoesterase HXTX; SPTR: 2'-5' RNA ligase; TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase family; TIGRFAM: 2'-5' RNA ligase; 2'-5' RNA ligase complement(2307305..2307829) Spirochaeta smaragdinae DSM 11293 9490246 YP_003803857.1 CDS Spirs_2143 NC_014364.1 2307877 2308650 R COGs: COG1381 recombinational DNA repair protein (RecF pathway); InterPro IPR003717; KEGG: hor:Hore_12480 DNA repair protein RecO; PFAM: recombination protein O RecO; SPTR: DNA repair protein RecO; TIGRFAM: DNA repair protein RecO; PFAM: recombination protein O C terminal; recombination protein O N terminal; TIGRFAM: DNA repair protein RecO; DNA repair protein RecO complement(2307877..2308650) Spirochaeta smaragdinae DSM 11293 9490247 YP_003803858.1 CDS Spirs_2144 NC_014364.1 2308774 2311116 D COGs: COG0466 ATP-dependent Lon protease; InterProIPR001984:IPR008268:IPR003111:IPR003593:IPR 003959:IPR008269:IPR004815; KEGG: tde:TDE0670 ATP-dependent protease La; PFAM: ATPase AAA; peptidase S16; PRIAM: endopeptidase La; SMART: peptidase S16; ATPase AAA; SPTR: ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La; ATP-dependent protease La 2308774..2311116 Spirochaeta smaragdinae DSM 11293 9490248 YP_003803859.1 CDS Spirs_2145 NC_014364.1 2311113 2312339 D COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: tde:TDE2262 U32 family peptidase; PFAM: peptidase U32; SPTR: peptidase, U32 family; PFAM: peptidase family U32; peptidase U32 2311113..2312339 Spirochaeta smaragdinae DSM 11293 9490249 YP_003803860.1 CDS Spirs_2146 NC_014364.1 2312413 2313930 R COGs: COG0112 glycine/serine hydroxymethyltransferase; InterPro IPR019798:IPR001085; KEGG: tde:TDE2668 serine hydroxymethyltransferase; PFAM: glycine hydroxymethyltransferase; PRIAM: glycine hydroxymethyltransferase; SPTR: serine hydroxymethyltransferase; PFAM: serine hydroxymethyltransferase; glycine hydroxymethyltransferase complement(2312413..2313930) Spirochaeta smaragdinae DSM 11293 9490250 YP_003803861.1 CDS Spirs_2147 NC_014364.1 2314147 2316792 R COGs: COG0525 Valyl-tRNA synthetase; InterProIPR019754:IPR001412:IPR002300:IPR013155:IPR 019499:IPR002303; KEGG: tde:TDE1364 valyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ia; tRNA synthetase valyl/leucyl anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA binding arm; SPTR: Valyl-tRNA synthetase; TIGRFAM: valyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase; valyl-tRNA synthetase complement(2314147..2316792) Spirochaeta smaragdinae DSM 11293 9490251 YP_003803862.1 CDS Spirs_2148 NC_014364.1 2316900 2317649 D COGs: COG2518 protein-L-isoaspartate carboxylmethyltransferase; InterPro IPR000682; KEGG: hut:Huta_2559 protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase; SPTR: L-isoaspartate protein carboxylmethyltransferase type II; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); protein-L-isoaspartate(D-aspartate)O-methyltrans ferase 2316900..2317649 Spirochaeta smaragdinae DSM 11293 9490252 YP_003803863.1 CDS Spirs_2149 NC_014364.1 2317656 2318891 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018488:IPR000595; KEGG: tde:TDE0067 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator complement(2317656..2318891) Spirochaeta smaragdinae DSM 11293 9490253 YP_003803864.1 CDS Spirs_2150 NC_014364.1 2318969 2320630 R COGs: COG1305 transglutaminase-like protein; InterPro IPR002931:IPR002909; KEGG: tde:TDE0089 transglutaminase-like domain-containing protein; PFAM: transglutaminase; cell surface receptor IPT/TIG domain protein; SMART: transglutaminase; SPTR: uncharacterized protein; PFAM: transglutaminase-like superfamily; IPT/TIG domain; transglutaminase complement(2318969..2320630) Spirochaeta smaragdinae DSM 11293 9490254 YP_003803865.1 CDS Spirs_2151 NC_014364.1 2320627 2321133 R KEGG: sbi:SORBI_05g026816 hypothetical protein; SPTR: Signal transduction protein containing membrane, EAL and GGDEF domains-like; hypothetical protein complement(2320627..2321133) Spirochaeta smaragdinae DSM 11293 9490255 YP_003803866.1 CDS Spirs_2152 NC_014364.1 2321130 2321723 R KEGG: tde:TDE0090 hypothetical protein; SPTR: uncharacterized protein; transmembrane anti-sigma factor complement(2321130..2321723) Spirochaeta smaragdinae DSM 11293 9490256 YP_003803867.1 CDS Spirs_2153 NC_014364.1 2321713 2322240 R COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: tde:TDE0091 RNA polymerase sigma-24 factor, PFAM: Sigma-70 region 4 type 2; sigma-70 region 2 domain protein; SPTR: RNA polymerase sigma-24 factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit complement(2321713..2322240) Spirochaeta smaragdinae DSM 11293 9490257 YP_003803868.1 CDS Spirs_2154 NC_014364.1 2322269 2323693 R COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR002308; KEGG: tde:TDE0092 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; PRIAM: cysteine--tRNA ligase; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: tRNA synthetases class I (C) catalytic domain; TIGRFAM: cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase complement(2322269..2323693) Spirochaeta smaragdinae DSM 11293 9490258 YP_003803869.1 CDS Spirs_2155 NC_014364.1 2323750 2324709 D COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR003170:IPR006094:IPR011601:IPR016166; KEGG: tde:TDE0093 UDP-N-acetylenolpyruvoylglucosamine reductase, PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase domain protein; FAD linked oxidase domain protein; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; UDP-N-acetylenolpyruvoylglucosamine reductase 2323750..2324709 Spirochaeta smaragdinae DSM 11293 9490259 YP_003803870.1 CDS Spirs_2156 NC_014364.1 2324706 2326052 D COGs: COG2239 Mg/Co/Ni transporter MgtE (contains CBS domain); InterPro IPR000644:IPR006668:IPR006667:IPR006669; KEGG: mrb:Mrub_2269 magnesium transporter; PFAM: MgtE integral membrane region; CBS domain containing protein; MgtE intracellular region; SPTR: Magnesium transporter; TIGRFAM: magnesium transporter; PFAM: MgtE intracellular N domain; Divalent cation transporter; CBS domain; TIGRFAM: Mg2+ transporter (mgtE); magnesium transporter 2324706..2326052 Spirochaeta smaragdinae DSM 11293 9490260 YP_003803871.1 CDS Spirs_2157 NC_014364.1 2326078 2327547 R KEGG: ecq:ECED1_5046 prophage integrase; SPTR: prophage integrase; hypothetical protein complement(2326078..2327547) Spirochaeta smaragdinae DSM 11293 9490261 YP_003803872.1 CDS Spirs_2158 NC_014364.1 2327559 2328899 D COGs: COG0282 acetate kinase; InterPro IPR000890:IPR004372; KEGG: tpp:TPASS_0476 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: acetate kinase; TIGRFAM: acetate kinase; PFAM: acetokinase family; TIGRFAM: acetate kinase; acetate kinase 2327559..2328899 Spirochaeta smaragdinae DSM 11293 9490262 YP_003803873.1 CDS Spirs_2159 NC_014364.1 2329685 2330950 D InterPro IPR002104; KEGG: sjp:SJA_C1-09870 integrase; PFAM: integrase family protein; SPTR: uncharacterized protein; PFAM: Phage integrase family; integrase family protein 2329685..2330950 Spirochaeta smaragdinae DSM 11293 9490265 YP_003803874.1 CDS Spirs_2160 NC_014364.1 2331412 2331927 R KEGG: ots:OTBS_1575 glutamine synthetase; SPTR: glutamine synthetase; hypothetical protein complement(2331412..2331927) Spirochaeta smaragdinae DSM 11293 9490266 YP_003803875.1 CDS Spirs_2161 NC_014364.1 2331924 2332307 R KEGG: bay:RBAM_003180 YceF; SPTR: YceF; hypothetical protein complement(2331924..2332307) Spirochaeta smaragdinae DSM 11293 9490267 YP_003803876.1 CDS Spirs_2162 NC_014364.1 2332404 2333627 R KEGG: cch:Cag_0445 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2332404..2333627) Spirochaeta smaragdinae DSM 11293 9490268 YP_003803877.1 CDS Spirs_2163 NC_014364.1 2333802 2334419 R KEGG: pfh:PFHG_03873 conserved hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2333802..2334419) Spirochaeta smaragdinae DSM 11293 9490269 YP_003803878.1 CDS Spirs_2164 NC_014364.1 2334416 2335471 R InterPro IPR004919; KEGG: shl:Shal_3269 hypothetical protein; PFAM: protein of unknown function DUF262; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF262; hypothetical protein complement(2334416..2335471) Spirochaeta smaragdinae DSM 11293 9490270 YP_003803879.1 CDS Spirs_2165 NC_014364.1 2335637 2336704 R InterPro IPR002345; KEGG: srm:SRM_00076 abortive phage resistance protein; SPTR: Predicted protein; hypothetical protein complement(2335637..2336704) Spirochaeta smaragdinae DSM 11293 9490271 YP_003803880.1 CDS Spirs_2166 NC_014364.1 2336829 2337170 R InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator complement(2336829..2337170) Spirochaeta smaragdinae DSM 11293 9490272 YP_003803881.1 CDS Spirs_2167 NC_014364.1 2337266 2337481 D KEGG: kfl:Kfla_1158 glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; glyoxalase/bleomycin resistance protein/dioxygenase 2337266..2337481 Spirochaeta smaragdinae DSM 11293 9490273 YP_003803882.1 CDS Spirs_2168 NC_014364.1 2337478 2337723 D KEGG: sat:SYN_00844 molybdate-binding protein domain; SPTR: Predicted protein; TIGRFAM: DNA binding domain, excisionase family; hypothetical protein 2337478..2337723 Spirochaeta smaragdinae DSM 11293 9490274 YP_003803883.1 CDS Spirs_2169 NC_014364.1 2337961 2338164 D KEGG: sen:SACE_3576 integral membrane protein MviN; SPTR: integral membrane protein MviN; hypothetical protein 2337961..2338164 Spirochaeta smaragdinae DSM 11293 9490275 YP_003803884.1 CDS Spirs_2170 NC_014364.1 2338734 2339270 D KEGG: eck:EC55989_2618 hypothetical protein; SPTR: Gp49; PFAM: protein of unknown function (DUF2829); hypothetical protein 2338734..2339270 Spirochaeta smaragdinae DSM 11293 9490276 YP_003803885.1 CDS Spirs_2171 NC_014364.1 2339267 2339521 D KEGG: cpo:COPRO5265_0570 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2339267..2339521 Spirochaeta smaragdinae DSM 11293 9490277 YP_003803886.1 CDS Spirs_2172 NC_014364.1 2339518 2340633 D KEGG: sit:TM1040_1687 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2339518..2340633 Spirochaeta smaragdinae DSM 11293 9490278 YP_003803887.1 CDS Spirs_2173 NC_014364.1 2340648 2341298 D KEGG: tva:TVAG_005450 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2340648..2341298 Spirochaeta smaragdinae DSM 11293 9490279 YP_003803888.1 CDS Spirs_2174 NC_014364.1 2341303 2341941 D KEGG: bpd:BURPS668_A2378 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2341303..2341941 Spirochaeta smaragdinae DSM 11293 9490280 YP_003803889.1 CDS Spirs_2175 NC_014364.1 2341938 2342411 D KEGG: gym:GYMC10_5472 Cof-like hydrolase; SPTR: Cof-like hydrolase; hypothetical protein 2341938..2342411 Spirochaeta smaragdinae DSM 11293 9490281 YP_003803890.1 CDS Spirs_2176 NC_014364.1 2342421 2342858 D KEGG: pdi:BDI_0857 recombination protein; SPTR: uncharacterized protein; hypothetical protein 2342421..2342858 Spirochaeta smaragdinae DSM 11293 9490282 YP_003803891.1 CDS Spirs_2177 NC_014364.1 2342868 2343407 D COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: tde:TDE1677 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein 2342868..2343407 Spirochaeta smaragdinae DSM 11293 9490283 YP_003803892.1 CDS Spirs_2178 NC_014364.1 2343420 2344475 D KEGG: ate:Athe_2433 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2343420..2344475 Spirochaeta smaragdinae DSM 11293 9490284 YP_003803893.1 CDS Spirs_2179 NC_014364.1 2344481 2344894 D KEGG: cbe:Cbei_1972 guanine deaminase; SPTR: Guanine deaminase; hypothetical protein 2344481..2344894 Spirochaeta smaragdinae DSM 11293 9490285 YP_003803894.1 CDS Spirs_2180 NC_014364.1 2344878 2345096 D KEGG: ptm:GSPATT00031175001 hypothetical protein; SPTR: chromosome undetermined scaffold_121, whole genome shotgun sequence; hypothetical protein 2344878..2345096 Spirochaeta smaragdinae DSM 11293 9490286 YP_003803895.1 CDS Spirs_2181 NC_014364.1 2345093 2345284 D hypothetical protein 2345093..2345284 Spirochaeta smaragdinae DSM 11293 9490287 YP_003803896.1 CDS Spirs_2182 NC_014364.1 2345308 2345487 D hypothetical protein 2345308..2345487 Spirochaeta smaragdinae DSM 11293 9490288 YP_003803897.1 CDS Spirs_2183 NC_014364.1 2345630 2346916 D KEGG: pub:SAR11_0932 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2345630..2346916 Spirochaeta smaragdinae DSM 11293 9490289 YP_003803898.1 CDS Spirs_2184 NC_014364.1 2347200 2348180 D KEGG: clu:CLUG_03274 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2347200..2348180 Spirochaeta smaragdinae DSM 11293 9490290 YP_003803899.1 CDS Spirs_2185 NC_014364.1 2348484 2348792 D KEGG: asu:Asuc_1234 HNH endonuclease; SPTR: HNH endonuclease; hypothetical protein 2348484..2348792 Spirochaeta smaragdinae DSM 11293 9490291 YP_003803900.1 CDS Spirs_2186 NC_014364.1 2348796 2349302 D COGs: COG3747 Phage terminase small subunit; InterPro IPR006448; KEGG: rsh:Rsph17029_0646 P27 family phage terminase small subunit; PFAM: terminase small subunit P27; SPTR: Phage terminase, small subunit, , P27 family; TIGRFAM: phage terminase, small subunit, , P27 family; PFAM: Phage terminase, small subunit; TIGRFAM: phage terminase, small subunit, , P27 family; phage terminase, small subunit, , P27 family 2348796..2349302 Spirochaeta smaragdinae DSM 11293 9490292 YP_003803901.1 CDS Spirs_2187 NC_014364.1 2349299 2350621 D COGs: COG4626 Phage terminase-like protein large subunit; InterPro IPR005021; KEGG: pag:PLES_25381 terminase; PFAM: terminase; SPTR: terminase; PFAM: Phage terminase; terminase 2349299..2350621 Spirochaeta smaragdinae DSM 11293 9490293 YP_003803902.1 CDS Spirs_2188 NC_014364.1 2350705 2351235 D KEGG: chl:Chy400_1398 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2350705..2351235 Spirochaeta smaragdinae DSM 11293 9490294 YP_003803903.1 CDS Spirs_2189 NC_014364.1 2351631 2351951 D COGs: COG4679 Phage-related protein; InterPro IPR009241; KEGG: dps:DPPB47 hypothetical protein; PFAM: protein of unknown function DUF891; SPTR: uncharacterized protein; manually curated; PFAM: Phage derived protein Gp49-like (DUF891); hypothetical protein 2351631..2351951 Spirochaeta smaragdinae DSM 11293 9490295 YP_003803904.1 CDS Spirs_2190 NC_014364.1 2351948 2352244 D InterPro IPR001387; KEGG: dps:DPPB46 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator 2351948..2352244 Spirochaeta smaragdinae DSM 11293 9490296 YP_003803905.1 CDS Spirs_2191 NC_014364.1 2352258 2352521 D InterPro IPR018841; KEGG: amt:Amet_0301 hypothetical protein; PFAM: protein of unknown function DUF2442; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2442); hypothetical protein 2352258..2352521 Spirochaeta smaragdinae DSM 11293 9490297 YP_003803906.1 CDS Spirs_2192 NC_014364.1 2352591 2352845 D COGs: COG2929 conserved hypothetical protein; InterPro IPR007460; KEGG: dol:Dole_0658 hypothetical protein; PFAM: protein of unknown function DUF497; SPTR: uncharacterized protein; manually curated; PFAM: protein of unknown function (DUF497); hypothetical protein 2352591..2352845 Spirochaeta smaragdinae DSM 11293 9490298 YP_003803907.1 CDS Spirs_2193 NC_014364.1 2352850 2353065 D KEGG: fsu:Fisuc_0795 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2352850..2353065 Spirochaeta smaragdinae DSM 11293 9490299 YP_003803908.1 CDS Spirs_2194 NC_014364.1 2353106 2353357 D KEGG: tde:TDE0264 CopG family transcriptional regulator; SPTR: Ribbon-helix-helix protein, CopG family; CopG family transcriptional regulator 2353106..2353357 Spirochaeta smaragdinae DSM 11293 9490300 YP_003803909.1 CDS Spirs_2196 NC_014364.1 2353705 2353947 D InterPro IPR003756:IPR006442; KEGG: dal:Dalk_1773 prevent-host-death family protein; PFAM: protein of unknown function DUF172; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein 2353705..2353947 Spirochaeta smaragdinae DSM 11293 9490302 YP_003803910.1 CDS Spirs_2197 NC_014364.1 2353947 2354207 D COGs: COG4115 conserved hypothetical protein; InterPro IPR007712:IPR012753:IPR009614; KEGG: dol:Dole_2607 addiction module antitoxin; PFAM: plasmid stabilization system; SPTR: Addiction module toxin, Txe/YoeB family; TIGRFAM: addiction module toxin, Txe/YoeB family; addiction module toxin, RelE/StbE family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: addiction module toxin, RelE/StbE family; toxin-antitoxin system, toxin component, Txe/YoeB family; Txe/YoeB family addiction module toxin 2353947..2354207 Spirochaeta smaragdinae DSM 11293 9490303 YP_003803911.1 CDS Spirs_2200 NC_014364.1 2355458 2355790 R InterPro IPR002514; KEGG: pvi:Cvib_1307 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase; transposase IS3/IS911 family protein complement(2355458..2355790) Spirochaeta smaragdinae DSM 11293 9490306 YP_003803912.1 CDS Spirs_2202 NC_014364.1 2356339 2357256 D COGs: COG2367 beta-lactamase class A; InterPro IPR000871:IPR001466; KEGG: aby:ABAYE3623 beta-lactamase VEB-1; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase; beta-lactamase 2356339..2357256 Spirochaeta smaragdinae DSM 11293 9490308 YP_003803913.1 CDS Spirs_2203 NC_014364.1 2357319 2358515 D COGs: COG3328 transposase and inactivated derivatives; InterPro IPR001207; KEGG: dap:Dacet_0663 transposase mutator type; PFAM: transposase mutator type; SPTR: transposase mutator type; PFAM: transposase, Mutator family; transposase mutator type 2357319..2358515 Spirochaeta smaragdinae DSM 11293 9490309 YP_003803914.1 CDS Spirs_2204 NC_014364.1 2358608 2358955 R KEGG: cbe:Cbei_2689 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2358608..2358955) Spirochaeta smaragdinae DSM 11293 9490310 YP_003803915.1 CDS Spirs_2205 NC_014364.1 2359136 2359336 R KEGG: dvm:DvMF_0755 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2359136..2359336) Spirochaeta smaragdinae DSM 11293 9490311 YP_003803916.1 CDS Spirs_2206 NC_014364.1 2359504 2360547 R COGs: COG3053 citrate lyase synthetase; InterPro IPR013166:IPR000182:IPR005216:IPR004821; KEGG: cpe:CPE1146 citrate (pro-3S)-lyase ligase; PFAM: citrate lyase ligase domain protein; GCN5-related N-acetyltransferase; PRIAM: [citrate (pro-3S)-lyase] ligase; SMART: citrate lyase ligase domain protein; SPTR: [citrate (Pro-3S)-lyase] ligase; TIGRFAM: citrate lyase ligase; cytidyltransferase-related domain protein; PFAM: acetyltransferase (GNAT) family; citrate lyase ligase C-terminal domain; TIGRFAM: [citrate (pro-3S)-lyase] ligase; cytidyltransferase-related domain; citrate lyase ligase complement(2359504..2360547) Spirochaeta smaragdinae DSM 11293 9490312 YP_003803917.1 CDS Spirs_2207 NC_014364.1 2360558 2361454 R COGs: COG1767 Triphosphoribosyl-dephospho-CoA synthetase; InterPro IPR002736:IPR017551; KEGG: amt:Amet_3408 triphosphoribosyl-dephospho-CoA synthase; PFAM: triphosphoribosyl-dephospho-CoA protein; PRIAM: Triphosphoribosyl-dephospho-CoA synthase; SPTR: Triphosphoribosyl-dephospho-CoA synthase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; PFAM: ATP:dephospho-CoA triphosphoribosyl transferase; TIGRFAM: triphosphoribosyl-dephospho-CoA synthase CitG; triphosphoribosyl-dephospho-CoA synthase CitG complement(2360558..2361454) Spirochaeta smaragdinae DSM 11293 9490313 YP_003803918.1 CDS Spirs_2208 NC_014364.1 2361417 2362013 R COGs: COG3697 phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase); InterPro IPR005551; KEGG: sub:SUB1585 puatative apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; PRIAM: citrate lyase holo-[acyl-carrier-protein] synthase; SPTR: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase/2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A synthase; TIGRFAM: holo-ACP synthase CitX; PFAM: Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase; TIGRFAM: holo-ACP synthase CitX; holo-ACP synthase CitX complement(2361417..2362013) Spirochaeta smaragdinae DSM 11293 9490314 YP_003803919.1 CDS Spirs_2209 NC_014364.1 2362003 2363559 R COGs: COG3051 citrate lyase subunit alpha; InterPro IPR006472; KEGG: smu:SMU.1021 citrate lyase, alfa subunit; PFAM: citrate lyase subunit alpha; PRIAM: citrate CoA-transferase; SPTR: citrate lyase, subunit alpha; TIGRFAM: citrate lyase subunit alpha; PFAM: citrate lyase, subunit alpha (CitF); TIGRFAM: citrate lyase subunit alpha; citrate lyase subunit alpha complement(2362003..2363559) Spirochaeta smaragdinae DSM 11293 9490315 YP_003803920.1 CDS Spirs_2210 NC_014364.1 2363570 2364448 R COGs: COG2301 citrate lyase subunit beta; InterPro IPR005000:IPR011206:IPR006475; KEGG: cpe:CPE1148 citrate lyase beta subunit; PFAM: HpcH/HpaI aldolase; PRIAM: Citryl-CoA lyase; SPTR: citrate lyase subunit beta; TIGRFAM: citrate lyase subunit beta; PFAM: HpcH/HpaI aldolase/citrate lyase family; TIGRFAM: citrate lyase subunit beta; citrate lyase subunit beta complement(2363570..2364448) Spirochaeta smaragdinae DSM 11293 9490316 YP_003803921.1 CDS Spirs_2211 NC_014364.1 2364451 2364741 R COGs: COG3052 citrate lyase subunit gamma; InterPro IPR006495; KEGG: smc:SmuNN2025_1004 citrate lyase gamma-subunit; PFAM: citrate lyase acyl carrier protein CitD; SPTR: citrate lyase gamma subunit; TIGRFAM: citrate lyase acyl carrier protein; PFAM: Malonate decarboxylase subunit delta (MdcD); TIGRFAM: citrate lyase acyl carrier protein; citrate lyase acyl carrier protein complement(2364451..2364741) Spirochaeta smaragdinae DSM 11293 9490317 YP_003803922.1 CDS Spirs_2212 NC_014364.1 2364751 2365557 R COGs: COG2819 hydrolase of the alpha/beta superfamily; InterPro IPR000801; KEGG: fno:Fnod_0083 esterase; PFAM: esterase; SPTR: uncharacterized protein; PFAM: esterase; esterase complement(2364751..2365557) Spirochaeta smaragdinae DSM 11293 9490318 YP_003803923.1 CDS Spirs_2213 NC_014364.1 2365722 2366753 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tex:Teth514_0161 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(2365722..2366753) Spirochaeta smaragdinae DSM 11293 9490319 YP_003803924.1 CDS Spirs_2214 NC_014364.1 2366781 2368619 R COGs: COG2936 acyl esterase; InterPro IPR000383:IPR013736:IPR005674; KEGG: ccs:CCNA_01694 7 beta-(4-carboxybutanamido)cephalosporanic acid acylase; PFAM: X-Pro dipeptidyl-peptidase domain protein; peptidase S15; SPTR: antibiotic hydrolase; TIGRFAM: hydrolase CocE/NonD family protein; PFAM: X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; X-Pro dipeptidyl-peptidase (S15 family); TIGRFAM: hydrolase, CocE/NonD family; hydrolase CocE/NonD family protein complement(2366781..2368619) Spirochaeta smaragdinae DSM 11293 9490320 YP_003803925.1 CDS Spirs_2215 NC_014364.1 2368631 2369596 R COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterProIPR017871:IPR003593:IPR003439:IPR013563:IPR 010066; KEGG: ttj:TTHA0473 peptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide transport ATP-binding protein appF; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase complement(2368631..2369596) Spirochaeta smaragdinae DSM 11293 9490321 YP_003803926.1 CDS Spirs_2216 NC_014364.1 2369589 2370554 R COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterPro IPR003593:IPR003439:IPR013563:IPR010066; KEGG: chy:CHY_1126 oligopeptide/dipeptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide ABC transporter ATP-binding protein OppD; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase complement(2369589..2370554) Spirochaeta smaragdinae DSM 11293 9490322 YP_003803927.1 CDS Spirs_2217 NC_014364.1 2370565 2371389 R COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: atc:AGR_L_3102 dipeptide abc transporter dipeptide-binding protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component; binding-protein-dependent transporters inner membrane component complement(2370565..2371389) Spirochaeta smaragdinae DSM 11293 9490323 YP_003803928.1 CDS Spirs_2218 NC_014364.1 2371404 2372336 R COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: sti:Sthe_3229 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component; binding-protein-dependent transporters inner membrane component complement(2371404..2372336) Spirochaeta smaragdinae DSM 11293 9490324 YP_003803929.1 CDS Spirs_2219 NC_014364.1 2372442 2374037 R COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: bpt:Bpet1584 ABC transporter periplasmic-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: Probable ABC transporter periplasmic binding protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein complement(2372442..2374037) Spirochaeta smaragdinae DSM 11293 9490325 YP_003803930.1 CDS Spirs_2220 NC_014364.1 2374506 2375303 D COGs: COG2819 hydrolase of the alpha/beta superfamily; InterPro IPR000801; KEGG: eat:EAT1b_1326 esterase; PFAM: esterase; SPTR: uncharacterized protein; PFAM: esterase; esterase 2374506..2375303 Spirochaeta smaragdinae DSM 11293 9490326 YP_003803931.1 CDS Spirs_2221 NC_014364.1 2375352 2376359 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: tte:TTE0201 transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 2375352..2376359 Spirochaeta smaragdinae DSM 11293 9490327 YP_003803932.1 CDS Spirs_2222 NC_014364.1 2376511 2377272 D COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; InterPro IPR003000; KEGG: tca:655430 similar to CG5216-PA; PFAM: silent information regulator protein Sir2; SPTR: NAD+-dependent deacetylase; PFAM: Sir2 family; silent information regulator protein Sir2 2376511..2377272 Spirochaeta smaragdinae DSM 11293 9490328 YP_003803933.1 CDS Spirs_2223 NC_014364.1 2377442 2379559 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004090:IPR010916:IPR003660:IPR004089; KEGG: tde:TDE2270 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 2377442..2379559 Spirochaeta smaragdinae DSM 11293 9490329 YP_003803934.1 CDS Spirs_2224 NC_014364.1 2379585 2380898 R InterPro IPR000792:IPR013767; KEGG: rec:RHECIAT_CH0000671 transcriptional regulator protein, LuxR family; PFAM: regulatory protein LuxR; PAS fold domain protein; SMART: regulatory protein LuxR; SPTR: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box; LuxR family transcriptional regulator complement(2379585..2380898) Spirochaeta smaragdinae DSM 11293 9490330 YP_003803935.1 CDS Spirs_2225 NC_014364.1 2381072 2382595 D COGs: COG4251 Bacteriophytochrome (light-regulated signal transduction histidine kinase); InterProIPR004358:IPR003661:IPR003594:IPR005467:IPR 000700; KEGG: geo:Geob_1250 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; histidine kinase 2381072..2382595 Spirochaeta smaragdinae DSM 11293 9490331 YP_003803936.1 CDS Spirs_2226 NC_014364.1 2382592 2384472 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR001789:IPR000014:IPR003661:IPR 003594:IPR013656:IPR005467; KEGG: dvl:Dvul_1102 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; PAS fold-4 domain protein; SMART: ATP-binding region ATPase domain protein; response regulator receiver; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; TIGRFAM: PAS domain S-box; PAS/PAC sensor hybrid histidine kinase 2382592..2384472 Spirochaeta smaragdinae DSM 11293 9490332 YP_003803937.1 CDS Spirs_2227 NC_014364.1 2384482 2384850 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: pph:Ppha_2765 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein 2384482..2384850 Spirochaeta smaragdinae DSM 11293 9490333 YP_003803938.1 CDS Spirs_2228 NC_014364.1 2384862 2385254 D KEGG: dsh:Dshi_1983 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2384862..2385254 Spirochaeta smaragdinae DSM 11293 9490334 YP_003803939.1 CDS Spirs_2229 NC_014364.1 2385247 2386296 D COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR020471:IPR001395; KEGG: mlo:mlr7180 hypothetical protein; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family; aldo/keto reductase 2385247..2386296 Spirochaeta smaragdinae DSM 11293 9490335 YP_003803940.1 CDS Spirs_2230 NC_014364.1 2386298 2388388 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR000014:IPR003661:IPR003594:IPR 013767:IPR005467; KEGG: cpo:COPRO5265_0030 PAS/PAC sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor signal transduction histidine kinase 2386298..2388388 Spirochaeta smaragdinae DSM 11293 9490336 YP_003803941.1 CDS Spirs_2231 NC_014364.1 2388385 2389374 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: taf:THA_1577 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(2388385..2389374) Spirochaeta smaragdinae DSM 11293 9490337 YP_003803942.1 CDS Spirs_2232 NC_014364.1 2389522 2390568 D COGs: COG0002 acetylglutamate semialdehyde dehydrogenase; InterPro IPR000706:IPR000534:IPR012280; KEGG: ere:EUBREC_1608 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase, common form; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form; N-acetyl-gamma-glutamyl-phosphate reductase 2389522..2390568 Spirochaeta smaragdinae DSM 11293 9490338 YP_003803943.1 CDS Spirs_2233 NC_014364.1 2390582 2391826 D COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); InterPro IPR002813; KEGG: dhd:Dhaf_0770 arginine biosynthesis bifunctional protein ArgJ; PFAM: arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: Arginine biosynthesis bifunctional protein ArgJ; TIGRFAM: arginine biosynthesis bifunctional protein ArgJ; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase; arginine biosynthesis bifunctional protein ArgJ 2390582..2391826 Spirochaeta smaragdinae DSM 11293 9490339 YP_003803944.1 CDS Spirs_2234 NC_014364.1 2391826 2392683 D COGs: COG0548 acetylglutamate kinase; InterPro IPR001057:IPR001048:IPR011148:IPR004662; KEGG: tpd:Teth39_0225 acetylglutamate kinase; PFAM: aspartate/glutamate/uridylate kinase; PRIAM: acetylglutamate kinase; SPTR: acetylglutamate kinase; TIGRFAM: acetylglutamate kinase; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase; acetylglutamate kinase 2391826..2392683 Spirochaeta smaragdinae DSM 11293 9490340 YP_003803945.1 CDS Spirs_2235 NC_014364.1 2392677 2393858 D COGs: COG4992 ornithine/acetylornithine aminotransferase; InterPro IPR005814:IPR004636; KEGG: kol:Kole_0097 acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; PRIAM: acetylornithine transaminase; SPTR: acetylornithine transaminase; TIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases; acetylornithine and succinylornithine aminotransferase 2392677..2393858 Spirochaeta smaragdinae DSM 11293 9490341 YP_003803946.1 CDS Spirs_2236 NC_014364.1 2393935 2394105 R KEGG: baf:BAPKO_0163 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2393935..2394105) Spirochaeta smaragdinae DSM 11293 9490342 YP_003803947.1 CDS Spirs_2238 NC_014364.1 2394556 2395056 R KEGG: azc:AZC_4047 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2394556..2395056) Spirochaeta smaragdinae DSM 11293 9490344 YP_003803948.1 CDS Spirs_2239 NC_014364.1 2395053 2395682 R COGs: COG0572 Uridine kinase; InterPro IPR000764:IPR006083; KEGG: btu:BT0015 uridine kinase; PFAM: phosphoribulokinase/uridine kinase; SPTR: Uridine kinase; TIGRFAM: uridine kinase; PFAM: phosphoribulokinase / Uridine kinase family; TIGRFAM: uridine kinase; uridine kinase complement(2395053..2395682) Spirochaeta smaragdinae DSM 11293 9490345 YP_003803949.1 CDS Spirs_2240 NC_014364.1 2395712 2396539 R COGs: COG4942 membrane-bound metallopeptidase; InterPro IPR002482:IPR018392:IPR016047; KEGG: tde:TDE1297 LysM/M23/M37 peptidase; PFAM: peptidase M23; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: LysM domain/M23/M37 peptidase domain protein; PFAM: peptidase family M23; LysM domain; peptidase M23 complement(2395712..2396539) Spirochaeta smaragdinae DSM 11293 9490346 YP_003803950.1 CDS Spirs_2241 NC_014364.1 2396646 2397983 D KEGG: lba:Lebu_1924 hypothetical protein; SPTR: uncharacterized protein; PFAM: alcohol acetyltransferase; hypothetical protein 2396646..2397983 Spirochaeta smaragdinae DSM 11293 9490347 YP_003803951.1 CDS Spirs_2242 NC_014364.1 2397955 2398671 D KEGG: lba:Lebu_1923 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2397955..2398671 Spirochaeta smaragdinae DSM 11293 9490348 YP_003803952.1 CDS Spirs_2243 NC_014364.1 2398698 2399249 R COGs: COG0693 intracellular protease/amidase; InterPro IPR002818:IPR006287; KEGG: tde:TDE2500 DJ-1 family protein; PFAM: ThiJ/PfpI domain protein; SPTR: DJ-1 family protein; TIGRFAM: DJ-1 family protein; PFAM: DJ-1/PfpI family; TIGRFAM: DJ-1 family protein; intracellular protease PfpI family; DJ-1 family protein complement(2398698..2399249) Spirochaeta smaragdinae DSM 11293 9490349 YP_003803953.1 CDS Spirs_2244 NC_014364.1 2399249 2400313 R COGs: COG0722 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006219; KEGG: cts:Ctha_2060 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: phospho-2-dehydro-3-deoxyheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; phospho-2-dehydro-3-deoxyheptonate aldolase complement(2399249..2400313) Spirochaeta smaragdinae DSM 11293 9490350 YP_003803954.1 CDS Spirs_2245 NC_014364.1 2400310 2402016 R COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: dde:Dde_0193 AMP-binding enzyme family protein; PFAM: AMP-dependent synthetase and ligase; SPTR: AMP-binding enzyme family protein; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase complement(2400310..2402016) Spirochaeta smaragdinae DSM 11293 9490351 YP_003803955.1 CDS Spirs_2246 NC_014364.1 2402013 2402798 R COGs: COG1235 metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: gtn:GTNG_3411 hypothetical protein; SPTR: beta-lactamase superfamily metal-dependent hydrolase; PFAM: metallo-beta-lactamase superfamily; hypothetical protein complement(2402013..2402798) Spirochaeta smaragdinae DSM 11293 9490352 YP_003803956.1 CDS Spirs_2247 NC_014364.1 2402801 2403145 R COGs: COG1393 Arsenate reductase and related protein glutaredoxin family; InterPro IPR006660; KEGG: lbf:LBF_2477 glutaredoxin family protein; PFAM: arsenate reductase; SPTR: arsenate reductase-like protein; PFAM: ArsC family; arsenate reductase-like protein complement(2402801..2403145) Spirochaeta smaragdinae DSM 11293 9490353 YP_003803957.1 CDS Spirs_2248 NC_014364.1 2403252 2404640 D COGs: COG0017 aspartyl/asparaginyl-tRNA synthetase; InterProIPR002312:IPR004365:IPR004364:IPR006195:IPR 004522; KEGG: tel:tlr2473 asparaginyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); nucleic acid binding OB-fold tRNA/helicase-type; PRIAM: Asparagine--tRNA ligase; SPTR: asparaginyl-tRNA synthetase; TIGRFAM: asparaginyl-tRNA synthetase; manually curated; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: asparaginyl-tRNA synthetase; asparaginyl-tRNA synthetase 2403252..2404640 Spirochaeta smaragdinae DSM 11293 9490354 YP_003803958.1 CDS Spirs_2249 NC_014364.1 2404637 2406496 R COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR010656:IPR004681; KEGG: afw:Anae109_0438 TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP dicarboxylate transporter DctM subunit; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; tripartite ATP-independent periplasmic transporters, DctQ component; TIGRFAM: TRAP transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM complement(2404637..2406496) Spirochaeta smaragdinae DSM 11293 9490355 YP_003803959.1 CDS Spirs_2250 NC_014364.1 2406493 2407488 R COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389; KEGG: dar:Daro_3577 TRAP dicarboxylate transporter-DctP subunit; PFAM: extracellular solute-binding protein, family 7; SPTR: Bacterial extracellular solute-binding protein, family 7; PFAM: Bacterial extracellular solute-binding protein, family 7; extracellular solute-binding protein, family 7 complement(2406493..2407488) Spirochaeta smaragdinae DSM 11293 9490356 YP_003803960.1 CDS Spirs_2251 NC_014364.1 2407490 2408515 R KEGG: afw:Anae109_0439 hypothetical protein; SPTR: lipoprotein; hypothetical protein complement(2407490..2408515) Spirochaeta smaragdinae DSM 11293 9490357 YP_003803961.1 CDS Spirs_2252 NC_014364.1 2408519 2408968 R COGs: COG1671 conserved hypothetical protein; InterPro IPR003791; KEGG: gbm:Gbem_2221 protein of unknown function DUF188; PFAM: protein of unknown function DUF188; SPTR: UPF0178 protein Gbem_2221; PFAM: Uncharacterized BCR, YaiI/YqxD family COG1671; hypothetical protein complement(2408519..2408968) Spirochaeta smaragdinae DSM 11293 9490358 YP_003803962.1 CDS Spirs_2253 NC_014364.1 2408952 2410178 R COGs: COG1482 phosphomannose isomerase; InterPro IPR016305:IPR018050:IPR001250; KEGG: dol:Dole_2015 mannose-6-phosphate isomerase, class I; PFAM: mannose-6-phosphate isomerase type I; PRIAM: mannose-6-phosphate isomerase; SPTR: mannose-6-phosphate isomerase, class I; TIGRFAM: mannose-6-phosphate isomerase, class I; PFAM: phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I; mannose-6-phosphate isomerase, class I complement(2408952..2410178) Spirochaeta smaragdinae DSM 11293 9490359 YP_003803963.1 CDS Spirs_2254 NC_014364.1 2410294 2411469 D COGs: COG0153 Galactokinase; InterPro IPR006206:IPR000705:IPR019539:IPR006204; KEGG: eel:EUBELI_01846 galactokinase; PFAM: GHMP kinase; Galactokinase galactose-binding domain; PRIAM: Galactokinase; SPTR: Galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases N terminal domain; TIGRFAM: galactokinase; Galactokinase 2410294..2411469 Spirochaeta smaragdinae DSM 11293 9490360 YP_003803964.1 CDS Spirs_2255 NC_014364.1 2411544 2413211 D COGs: COG0205 6-phosphofructokinase; InterPro IPR000023:IPR011183; KEGG: bth:BT_0307 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase; SPTR: Pyrophosphate-dependent phosphofructokinase; TIGRFAM: diphosphate/fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase; TIGRFAM: diphosphate--fructose-6-phosphate 1-phosphotransferase; diphosphate/fructose-6-phosphate1-phosphotransfe rase 2411544..2413211 Spirochaeta smaragdinae DSM 11293 9490361 YP_003803965.1 CDS Spirs_2256 NC_014364.1 2413253 2415808 D KEGG: ckp:ckrop_0164 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2413253..2415808 Spirochaeta smaragdinae DSM 11293 9490362 YP_003803966.1 CDS Spirs_2257 NC_014364.1 2415824 2416663 R COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tte:TTE2419 transcriptional regulator; PFAM: sugar isomerase (SIS); helix-turn-helix protein RpiR; SPTR: transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator complement(2415824..2416663) Spirochaeta smaragdinae DSM 11293 9490363 YP_003803967.1 CDS Spirs_2258 NC_014364.1 2416663 2417709 R COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: rle:RL3812 hypothetical protein; PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain; sugar isomerase (SIS) complement(2416663..2417709) Spirochaeta smaragdinae DSM 11293 9490364 YP_003803968.1 CDS Spirs_2259 NC_014364.1 2417713 2418603 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cte:CT0008 Rok family protein; PFAM: ROK family protein; SPTR: ROK family protein; manually curated; PFAM: ROK family; ROK family protein complement(2417713..2418603) Spirochaeta smaragdinae DSM 11293 9490365 YP_003803969.1 CDS Spirs_2260 NC_014364.1 2418606 2419451 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ddr:Deide_3p01830 sugar ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2418606..2419451) Spirochaeta smaragdinae DSM 11293 9490366 YP_003803970.1 CDS Spirs_2261 NC_014364.1 2419461 2420339 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: sme:SM_b21220 sugar uptake ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2419461..2420339) Spirochaeta smaragdinae DSM 11293 9490367 YP_003803971.1 CDS Spirs_2262 NC_014364.1 2420340 2421608 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: smd:Smed_4557 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2420340..2421608) Spirochaeta smaragdinae DSM 11293 9490368 YP_003803972.1 CDS Spirs_2263 NC_014364.1 2421787 2423970 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: dba:Dbac_1148 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 2421787..2423970 Spirochaeta smaragdinae DSM 11293 9490369 YP_003803973.1 CDS Spirs_2264 NC_014364.1 2423992 2425251 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR018211:IPR001670; KEGG: tbd:Tbd_1767 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(2423992..2425251) Spirochaeta smaragdinae DSM 11293 9490370 YP_003803974.1 CDS Spirs_2265 NC_014364.1 2425254 2425562 R COGs: COG1534 RNA-binding protein containing KH domain possibly ribosomal protein; InterPro IPR001890:IPR017924; KEGG: hau:Haur_3572 hypothetical protein; PFAM: protein of unknown function UPF0044; SPTR: uncharacterized protein; PFAM: CRS1 / YhbY (CRM) domain; TIGRFAM: conserved hypothetical protein TIGR00253; hypothetical protein complement(2425254..2425562) Spirochaeta smaragdinae DSM 11293 9490371 YP_003803975.1 CDS Spirs_2266 NC_014364.1 2425572 2426747 R KEGG: tde:TDE1451 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2425572..2426747) Spirochaeta smaragdinae DSM 11293 9490372 YP_003803976.1 CDS Spirs_2267 NC_014364.1 2426748 2428481 R COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tde:TDE0942 long-chain-fatty-acid--CoA ligase, PFAM: AMP-dependent synthetase and ligase; SPTR: long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase complement(2426748..2428481) Spirochaeta smaragdinae DSM 11293 9490373 YP_003803977.1 CDS Spirs_2268 NC_014364.1 2428579 2430519 D COGs: COG0465 ATP-dependent Zn protease; InterProIPR003960:IPR003593:IPR011546:IPR003959:IPR 000642:IPR005936; KEGG: tde:TDE0470 cell division protein FtsH; PFAM: peptidase M41; ATPase AAA; peptidase M41 FtsH extracellular; PRIAM: microtubule-severing ATPase; SMART: ATPase AAA; SPTR: cell division protease FtsH homolog; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: FtsH extracellular; peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH; ATP-dependent metalloprotease FtsH 2428579..2430519 Spirochaeta smaragdinae DSM 11293 9490374 YP_003803978.1 CDS Spirs_2269 NC_014364.1 2430479 2431285 R COGs: COG2935 arginyl-tRNA:protein arginylyltransferase; InterPro IPR007471:IPR007472; KEGG: mca:MCA1791 arginyl-tRNA-protein transferase; PFAM: Arginine-tRNA-protein transferase domain protein; SPTR: uncharacterized protein; PFAM: Arginine-tRNA-protein transferase, C terminus; Arginine-tRNA-protein transferase, N terminus; Arginine-tRNA-protein transferase domain-containing protein complement(2430479..2431285) Spirochaeta smaragdinae DSM 11293 9490375 YP_003803979.1 CDS Spirs_2270 NC_014364.1 2431376 2432671 D COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131; KEGG: cyc:PCC7424_2689 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase; histidinol dehydrogenase 2431376..2432671 Spirochaeta smaragdinae DSM 11293 9490376 YP_003803980.1 CDS Spirs_2271 NC_014364.1 2432675 2434009 D COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR018109:IPR013221:IPR004101:IPR001645; KEGG: tde:TDE1084 folylpolyglutamate synthetase, PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: Folylpolyglutamate synthetase, ; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase; FolC bifunctional protein 2432675..2434009 Spirochaeta smaragdinae DSM 11293 9490377 YP_003803981.1 CDS Spirs_2272 NC_014364.1 2434014 2435108 D COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861; KEGG: sat:SYN_01517 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; histidinol-phosphate aminotransferase 2434014..2435108 Spirochaeta smaragdinae DSM 11293 9490378 YP_003803982.1 CDS Spirs_2273 NC_014364.1 2435105 2435650 D COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR001969:IPR002589; KEGG: ent:Ent638_1561 hypothetical protein; PFAM: Appr-1-p processing domain protein; SMART: Appr-1-p processing domain protein; SPTR: Appr-1-p processing domain protein; PFAM: Macro domain; Appr-1-p processing domain-containing protein 2435105..2435650 Spirochaeta smaragdinae DSM 11293 9490379 YP_003803983.1 CDS Spirs_2274 NC_014364.1 2435651 2437102 D COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tde:TDE1579 fibronectin/fibrinogen-binding protein, internal deletion; PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; SPTR: Fibronectin/fibrinogen-binding protein, internal deletion; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA); Fibronectin-binding A domain-containing protein 2435651..2437102 Spirochaeta smaragdinae DSM 11293 9490380 YP_003803984.1 CDS Spirs_2275 NC_014364.1 2437099 2437635 D COGs: COG2078 conserved hypothetical protein; InterPro IPR002733; KEGG: drt:Dret_0462 AMMECR1 domain protein; PFAM: AMMECR1 domain protein; SPTR: AMMECR1 domain protein; PFAM: AMMECR1; TIGRFAM: conserved hypothetical protein TIGR00296; AMMECR1 domain-containing protein 2437099..2437635 Spirochaeta smaragdinae DSM 11293 9490381 YP_003803985.1 CDS Spirs_2276 NC_014364.1 2437649 2439106 D KEGG: osa:4332665 hypothetical protein; SPTR: acyltransferase family protein; hypothetical protein 2437649..2439106 Spirochaeta smaragdinae DSM 11293 9490382 YP_003803986.1 CDS Spirs_2277 NC_014364.1 2439087 2440073 R KEGG: geo:Geob_1695 FecR protein; SPTR: FecR protein; PFAM: FecR protein; hypothetical protein complement(2439087..2440073) Spirochaeta smaragdinae DSM 11293 9490383 YP_003803987.1 CDS Spirs_2278 NC_014364.1 2440079 2440993 R COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR002627:IPR018022; KEGG: tde:TDE0057 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase 1; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; manually curated; PFAM: IPP transferase; TIGRFAM: tRNA isopentenyltransferase (miaA); tRNA delta(2)-isopentenylpyrophosphate transferase complement(2440079..2440993) Spirochaeta smaragdinae DSM 11293 9490384 YP_003803988.1 CDS Spirs_2279 NC_014364.1 2441005 2441196 R InterPro IPR006110; KEGG: tde:TDE0056 DNA-directed RNA polymerase, omega subunit, PFAM: RNA polymerase Rpb6; SPTR: RNA polymerases K / 14 to 18 kDa subunit; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase subunit omega; RNA polymerase Rpb6 complement(2441005..2441196) Spirochaeta smaragdinae DSM 11293 9490385 YP_003803989.1 CDS Spirs_2280 NC_014364.1 2441248 2441808 R COGs: COG1102 Cytidylate kinase; InterPro IPR011892; KEGG: tde:TDE1087 cytidylate kinase; SPTR: cytidylate kinase; TIGRFAM: cytidylate kinase; PFAM: Cytidylate kinase; TIGRFAM: cytidylate kinase; cytidylate kinase complement(2441248..2441808) Spirochaeta smaragdinae DSM 11293 9490386 YP_003803990.1 CDS Spirs_2281 NC_014364.1 2441798 2442664 R COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR013551:IPR005229; KEGG: tde:TDE1086 hypothetical protein; PFAM: YicC domain protein; domain of unknown function DUF1732; SPTR: uncharacterized protein; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: conserved hypothetical protein TIGR00255; YicC domain-containing protein complement(2441798..2442664) Spirochaeta smaragdinae DSM 11293 9490387 YP_003803991.1 CDS Spirs_2282 NC_014364.1 2442661 2444121 R COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; InterPro IPR005758:IPR000713:IPR013221:IPR004101; KEGG: tpp:TPASS_0341 UDP-N-acetylmuramate--L-alanine ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; SPTR: UDP-N-acetylmuramate--alanine ligase; TIGRFAM: UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase; UDP-N-acetylmuramate/alanine ligase complement(2442661..2444121) Spirochaeta smaragdinae DSM 11293 9490388 YP_003803992.1 CDS Spirs_2283 NC_014364.1 2444359 2445585 D COGs: COG1295 membrane protein; InterPro IPR004664:IPR017039; KEGG: gsu:GSU2460 ribonuclease BN, PFAM: ribonuclease BN; SPTR: ribonuclease BN, ; TIGRFAM: ribonuclease BN; PFAM: ribonuclease BN-like family; TIGRFAM: YihY family protein (not ribonuclease BN); ribonuclease BN 2444359..2445585 Spirochaeta smaragdinae DSM 11293 9490389 YP_003803993.1 CDS Spirs_2284 NC_014364.1 2445582 2447108 D COGs: COG2843 protein of poly-gamma-glutamate biosynthesis (capsule formation); InterPro IPR019079; KEGG: bbe:BBR47_37540 hypothetical protein; PFAM: capsule synthesis protein, CapA; SPTR: uncharacterized protein; PFAM: Bacterial capsule synthesis protein PGA_cap; capsule synthesis protein, CapA 2445582..2447108 Spirochaeta smaragdinae DSM 11293 9490390 YP_003803994.1 CDS Spirs_2285 NC_014364.1 2447213 2447398 R KEGG: tde:TDE0793 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2447213..2447398) Spirochaeta smaragdinae DSM 11293 9490391 YP_003803995.1 CDS Spirs_2286 NC_014364.1 2447432 2448148 R COGs: COG0775 nucleoside phosphorylase; InterPro IPR000845; KEGG: cff:CFF8240_1515 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; PFAM: purine or other phosphorylase family 1; SPTR: MTA/SAH nucleosidase; PFAM: phosphorylase superfamily; purine or other phosphorylase family 1 complement(2447432..2448148) Spirochaeta smaragdinae DSM 11293 9490392 YP_003803996.1 CDS Spirs_2287 NC_014364.1 2448145 2448990 R COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200; KEGG: dat:HRM2_23340 periplasmic soluble lytic transglycosylase fused to ABC-type amino acid-binding protein (SLT domain fusion protein); PFAM: haloacid dehalogenase type 3; SPTR: Periplasmic soluble lytic transglycosylase fused to ABC-type amino acid-binding protein (SLT domain fusion protein); PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; haloacid dehalogenase type 3 complement(2448145..2448990) Spirochaeta smaragdinae DSM 11293 9490393 YP_003803997.1 CDS Spirs_2288 NC_014364.1 2448974 2449849 R COGs: COG2240 pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: dat:HRM2_15500 PdxK; PFAM: phosphomethylpyrimidine kinase type-1; SPTR: PdxK; PFAM: phosphomethylpyrimidine kinase; TIGRFAM: pyridoxal kinase; phosphomethylpyrimidine kinase type-1 complement(2448974..2449849) Spirochaeta smaragdinae DSM 11293 9490394 YP_003803998.1 CDS Spirs_2289 NC_014364.1 2449956 2451803 D COGs: COG1109 phosphomannomutase; InterPro IPR005844; KEGG: tde:TDE0864 phosphohexose mutase family protein; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; SPTR: phosphohexose mutase family protein; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I 2449956..2451803 Spirochaeta smaragdinae DSM 11293 9490395 YP_003803999.1 CDS Spirs_2290 NC_014364.1 2451785 2452591 R COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265; KEGG: gsu:GSU1613 A/G-specific adenine glycosylase, PFAM: HhH-GPD family protein; SMART: HhH-GPD family protein; SPTR: A/G-specific adenine glycosylase, ; PFAM: HhH-GPD superfamily base excision DNA repair protein; HhH-GPD family protein complement(2451785..2452591) Spirochaeta smaragdinae DSM 11293 9490396 YP_003804000.1 CDS Spirs_2291 NC_014364.1 2452646 2453737 R COGs: COG0628 permease; InterPro IPR002549; KEGG: aco:Amico_1764 protein of unknown function UPF0118; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20; hypothetical protein complement(2452646..2453737) Spirochaeta smaragdinae DSM 11293 9490397 YP_003804001.1 CDS Spirs_2292 NC_014364.1 2453773 2454297 R COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: glo:Glov_1734 chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: chemotaxis protein CheW; PFAM: CheW-like domain; chemotaxis protein CheW complement(2453773..2454297) Spirochaeta smaragdinae DSM 11293 9490398 YP_003804002.1 CDS Spirs_2293 NC_014364.1 2454385 2455392 R COGs: COG0825 acetyl-CoA carboxylase alpha subunit; InterPro IPR001095:IPR020582:IPR011763; KEGG: tde:TDE0589 acetyl-CoA carboxylase, carboxyl transferase, subunit alpha; PFAM: acetyl-CoA carboxylase, subunit alpha, conserved region; PRIAM: acetyl-CoA carboxylase; SPTR: acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; PFAM: acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, subunit alpha; acetyl-CoA carboxylase, carboxyl transferase subunit alpha complement(2454385..2455392) Spirochaeta smaragdinae DSM 11293 9490399 YP_003804003.1 CDS Spirs_2294 NC_014364.1 2455389 2456312 R COGs: COG0777 acetyl-CoA carboxylase beta subunit; InterPro IPR000438:IPR000022:IPR011762; KEGG: tde:TDE0590 acetyl-CoA carboxylase, carboxyl transferase subunit beta; PFAM: carboxyl transferase; SPTR: acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase, beta subunit; PFAM: carboxyl transferase domain; TIGRFAM: acetyl-CoA carboxylase, carboxyl transferase subunit beta; acetyl-CoA carboxylase, carboxyl transferase subunit beta complement(2455389..2456312) Spirochaeta smaragdinae DSM 11293 9490400 YP_003804004.1 CDS Spirs_2295 NC_014364.1 2456312 2457631 R COGs: COG0439 Biotin carboxylase; InterProIPR005479:IPR005481:IPR005482:IPR011761:IPR 011764:IPR004549; KEGG: tde:TDE0591 acetyl-CoA carboxylase, biotin carboxylase; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; SPTR: acetyl-CoA carboxylase, biotin carboxylase; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; acetyl-CoA carboxylase, biotin carboxylase complement(2456312..2457631) Spirochaeta smaragdinae DSM 11293 9490401 YP_003804005.1 CDS Spirs_2296 NC_014364.1 2457649 2458086 R COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR001249:IPR001882:IPR000089; KEGG: nam:NAMH_0057 acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: acetyl-CoA carboxylase, biotin carboxyl carrier protein; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: Biotin-requiring enzyme; TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; acetyl-CoA carboxylase, biotin carboxyl carrier protein complement(2457649..2458086) Spirochaeta smaragdinae DSM 11293 9490402 YP_003804006.1 CDS Spirs_2297 NC_014364.1 2458270 2459259 D COGs: COG0332 3-oxoacyl-(acyl-carrier-protein); InterPro IPR004655:IPR013751:IPR013747; KEGG: pth:PTH_1745 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; PRIAM: beta-ketoacyl-acyl-carrier-protein synthase III; SPTR: 3-oxoacyl-(acyl-carrier-protein) synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) synthase III; 3-oxoacyl-(acyl-carrier-protein) synthase III 2458270..2459259 Spirochaeta smaragdinae DSM 11293 9490403 YP_003804007.1 CDS Spirs_2298 NC_014364.1 2459266 2460216 D COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043; KEGG: fnu:FN0149 malonyl-CoA-[acyl-carrier-protein] transacylase; PFAM: acyl transferase; SPTR: uncharacterized protein; PFAM: acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; acyl transferase 2459266..2460216 Spirochaeta smaragdinae DSM 11293 9490404 YP_003804008.1 CDS Spirs_2299 NC_014364.1 2460229 2460954 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002347:IPR002198:IPR011284; KEGG: tde:TDE0598 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-(acyl-carrier-protein) reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; 3-oxoacyl-(acyl-carrier-protein) reductase 2460229..2460954 Spirochaeta smaragdinae DSM 11293 9490405 YP_003804009.1 CDS Spirs_2300 NC_014364.1 2460977 2462230 D COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR018201:IPR014030:IPR014031:IPR017568; KEGG: tde:TDE0038 3-oxoacyl-(acyl-carrier-protein) synthase II; PFAM: beta-ketoacyl synthase; SPTR: 3-oxoacyl-(acyl-carrier-protein) synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; PFAM: beta-ketoacyl synthase, N-terminal domain; beta-ketoacyl synthase, C-terminal domain; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; 3-oxoacyl-(acyl-carrier-protein) synthase 2 2460977..2462230 Spirochaeta smaragdinae DSM 11293 9490406 YP_003804010.1 CDS Spirs_2301 NC_014364.1 2462227 2462688 D COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR013114; KEGG: tde:TDE0823 (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase, PFAM: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase, ; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ; beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ 2462227..2462688 Spirochaeta smaragdinae DSM 11293 9490407 YP_003804011.1 CDS Spirs_2302 NC_014364.1 2462692 2463876 D COGs: COG3007 Uncharacterized paraquat-inducible protein B; InterPro IPR010758; KEGG: fjo:Fjoh_3464 trans-2-enoyl-CoA reductase; PFAM: short-chain alcohol dehydrogenase; PRIAM: trans-2-enoyl-CoA reductase (NAD(+)); SPTR: reductase Fjoh_3464; PFAM: trans-2-enoyl-CoA reductase catalytic region; NAD(P)H binding domain of trans-2-enoyl-CoA reductase; enoyl reductase FAD binding domain; trans-2-enoyl-CoA reductase (NAD(+)) 2462692..2463876 Spirochaeta smaragdinae DSM 11293 9490408 YP_003804012.1 CDS Spirs_2303 NC_014364.1 2463900 2464475 R InterPro IPR001387:IPR013096; KEGG: psl:Psta_4384 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; cupin; SMART: helix-turn-helix domain protein; SPTR: XRE family transcriptional regulator; PFAM: Cupin domain; Helix-turn-helix; XRE family transcriptional regulator complement(2463900..2464475) Spirochaeta smaragdinae DSM 11293 9490409 YP_003804013.1 CDS Spirs_2304 NC_014364.1 2464676 2465383 D COGs: COG0565 rRNA methylase; InterPro IPR001537:IPR004384; KEGG: tde:TDE2084 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RNA methyltransferase, TrmH family; TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: SpoU rRNA methylase family; TIGRFAM: RNA methyltransferase, TrmH family, group 1; RNA methyltransferase, TrmH family, group 1 2464676..2465383 Spirochaeta smaragdinae DSM 11293 9490410 YP_003804014.1 CDS Spirs_2305 NC_014364.1 2465401 2467560 R InterPro IPR001054; KEGG: sfu:Sfum_0558 adenylate/guanylate cyclase; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase; PFAM: adenylate and Guanylate cyclase catalytic domain; adenylate/guanylate cyclase complement(2465401..2467560) Spirochaeta smaragdinae DSM 11293 9490411 YP_003804015.1 CDS Spirs_2306 NC_014364.1 2467778 2469124 R COGs: COG4399 conserved hypothetical protein; InterPro IPR007383; KEGG: pca:Pcar_0273 hypothetical protein; PFAM: protein of unknown function DUF445; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF445); hypothetical protein complement(2467778..2469124) Spirochaeta smaragdinae DSM 11293 9490412 YP_003804016.1 CDS Spirs_2307 NC_014364.1 2469125 2469520 R InterPro IPR013247; KEGG: lbf:LBF_3283 hypothetical lipoprotein; PFAM: SH3 type 3 domain protein; SPTR: uncharacterized protein; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein complement(2469125..2469520) Spirochaeta smaragdinae DSM 11293 9490413 YP_003804017.1 CDS Spirs_2308 NC_014364.1 2469557 2470126 D KEGG: avi:Avi_5517 ABC transporter membrane spanning protein (oligopeptide); SPTR: ABC transporter transmembrane protein (oligopeptide); hypothetical protein 2469557..2470126 Spirochaeta smaragdinae DSM 11293 9490414 YP_003804018.1 CDS Spirs_2309 NC_014364.1 2470176 2470367 D KEGG: bav:BAV2650 capsular polysaccharide biosynthesis protein; SPTR: type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB; hypothetical protein 2470176..2470367 Spirochaeta smaragdinae DSM 11293 9490415 YP_003804019.1 CDS Spirs_2310 NC_014364.1 2470364 2471173 D InterPro IPR006037; KEGG: nhl:Nhal_3582 TrkA-C domain protein; PFAM: TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: TrkA-C domain; TrkA-C domain-containing protein 2470364..2471173 Spirochaeta smaragdinae DSM 11293 9490416 YP_003804020.1 CDS Spirs_2311 NC_014364.1 2471178 2472884 D COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR003594:IPR015168:IPR005467; KEGG: dba:Dbac_1513 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: NMT1/THI5 like domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; NMT1/THI5 like; histidine kinase 2471178..2472884 Spirochaeta smaragdinae DSM 11293 9490417 YP_003804021.1 CDS Spirs_2312 NC_014364.1 2472916 2473776 D InterPro IPR018247:IPR011600; KEGG: ddf:DEFDS_0903 hypothetical protein; PFAM: peptidase C14 caspase catalytic subunit p20; SPTR: Caspase domain protein; PFAM: Caspase domain; peptidase C14 caspase catalytic subunit p20 2472916..2473776 Spirochaeta smaragdinae DSM 11293 9490418 YP_003804022.1 CDS Spirs_2313 NC_014364.1 2473805 2474443 R KEGG: oih:OB2333 hypothetical protein; SPTR: Hypothetical conserved protein; hypothetical protein complement(2473805..2474443) Spirochaeta smaragdinae DSM 11293 9490419 YP_003804023.1 CDS Spirs_2314 NC_014364.1 2474560 2475678 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 2474560..2475678 Spirochaeta smaragdinae DSM 11293 9490420 YP_003804024.1 CDS Spirs_2315 NC_014364.1 2475735 2477237 D COGs: COG0367 Asparagine synthase (glutamine-hydrolyzing); InterPro IPR000583:IPR001962:IPR017932:IPR006426; KEGG: cyt:cce_4003 asparagine synthetase B; PFAM: asparagine synthase; glutamine amidotransferase class-II; SPTR: Asparagine synthase, glutamine-hydrolyzing; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: Asparagine synthase; glutamine amidotransferases class-II; TIGRFAM: asparagine synthase (glutamine-hydrolyzing); asparagine synthase 2475735..2477237 Spirochaeta smaragdinae DSM 11293 9490421 YP_003804025.1 CDS Spirs_2316 NC_014364.1 2477238 2478272 R COGs: COG3920 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR011495:IPR003594:IPR 005467; KEGG: cyh:Cyan8802_0440 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; hypothetical protein; ATP-binding region ATPase domain protein; SMART: PAS domain containing protein; SPTR: Signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase complement(2477238..2478272) Spirochaeta smaragdinae DSM 11293 9490422 YP_003804026.1 CDS Spirs_2317 NC_014364.1 2478269 2478883 R COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; KEGG: cyh:Cyan8802_0954 chemotaxis protein CheC; SPTR: chemotaxis protein CheC; chemotaxis protein CheC complement(2478269..2478883) Spirochaeta smaragdinae DSM 11293 9490423 YP_003804027.1 CDS Spirs_2318 NC_014364.1 2478890 2479255 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ter:Tery_4223 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(2478890..2479255) Spirochaeta smaragdinae DSM 11293 9490424 YP_003804028.1 CDS Spirs_2319 NC_014364.1 2479349 2480017 D COGs: COG1272 membrane protein hemolysin III homolog; InterPro IPR004254; KEGG: amt:Amet_4260 hemolysin III family channel protein; PFAM: Hly-III family protein; SPTR: Channel protein, hemolysin III family; PFAM: Haemolysin-III related; TIGRFAM: channel protein, hemolysin III family; Hly-III family protein 2479349..2480017 Spirochaeta smaragdinae DSM 11293 9490425 YP_003804029.1 CDS Spirs_2320 NC_014364.1 2480022 2481758 D COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: tde:TDE0942 long-chain-fatty-acid--CoA ligase, PFAM: AMP-dependent synthetase and ligase; SPTR: Long-chain-fatty-acid--CoA ligase, ; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase 2480022..2481758 Spirochaeta smaragdinae DSM 11293 9490426 YP_003804030.1 CDS Spirs_2321 NC_014364.1 2481785 2482435 R COGs: COG2872 metal-dependent hydrolase related to alanyl-tRNA synthetase HxxxH domain; InterPro IPR012947; KEGG: vex:VEA_003302 alanyl-tRNA synthetase domain protein; PFAM: threonyl/alanyl tRNA synthetase SAD; SPTR: alanyl-tRNA synthetase; PFAM: threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); threonyl/alanyl tRNA synthetase SAD complement(2481785..2482435) Spirochaeta smaragdinae DSM 11293 9490427 YP_003804031.1 CDS Spirs_2322 NC_014364.1 2482445 2483236 R COGs: COG1101 ABC-type uncharacterized transporter ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: gsu:GSU0212 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(2482445..2483236) Spirochaeta smaragdinae DSM 11293 9490428 YP_003804032.1 CDS Spirs_2323 NC_014364.1 2483233 2484129 R COGs: COG4120 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: dat:HRM2_37770 ABC-type transporter permease; PFAM: inner-membrane translocator; SPTR: ABC-type transporter permease; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(2483233..2484129) Spirochaeta smaragdinae DSM 11293 9490429 YP_003804033.1 CDS Spirs_2324 NC_014364.1 2484150 2485178 R COGs: COG2984 ABC-type uncharacterized transporter periplasmic component; InterPro IPR007487; KEGG: gsu:GSU0210 hypothetical protein; PFAM: protein of unknown function DUF534; SPTR: uncharacterized protein; PFAM: ABC transporter substrate binding protein; hypothetical protein complement(2484150..2485178) Spirochaeta smaragdinae DSM 11293 9490430 YP_003804034.1 CDS Spirs_2325 NC_014364.1 2485327 2486025 D COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005833:IPR005834:IPR006402; KEGG: cme:CMT388C unknown phosphatase CbbY; PFAM: haloacid dehalogenase; SPTR: Predicted protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; HAD-superfamily hydrolase 2485327..2486025 Spirochaeta smaragdinae DSM 11293 9490431 YP_003804035.1 CDS Spirs_2326 NC_014364.1 2486037 2487437 R COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR000759:IPR013027:IPR006005; KEGG: mab:MAB_0092 glutamate synthase subunit beta; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: Probable NADH-dependent glutamate synthase (Small subunit) GltD; TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthases, NADH/NADPH, small subunit; glutamate synthase, NADH/NADPH, small subunit complement(2486037..2487437) Spirochaeta smaragdinae DSM 11293 9490432 YP_003804036.1 CDS Spirs_2327 NC_014364.1 2487439 2491968 R COGs: COG0069 glutamate synthase domain 2; InterProIPR000583:IPR006982:IPR002932:IPR002489:IPR 017932; KEGG: sus:acid_3816 glutamate synthase (NADH) large subunit; PFAM: ferredoxin-dependent glutamate synthase; glutamine amidotransferase class-II; glutamate synthase; glutamate synthase subunit alpha domain protein; PRIAM: glutamate synthase (ferredoxin); SPTR: glutamate synthase (NADH) large subunit; PFAM: Conserved region in glutamate synthase; GXGXG motif; glutamate synthase central domain; glutamine amidotransferases class-II; glutamate synthase (ferredoxin) complement(2487439..2491968) Spirochaeta smaragdinae DSM 11293 9490433 YP_003804037.1 CDS Spirs_2328 NC_014364.1 2492209 2493837 R COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR000629:IPR014001:IPR001650:IPR011545:IPR 005580:IPR014021:IPR014014; KEGG: dba:Dbac_2473 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase; helicase; DbpA RNA-binding domain protein; SMART: DEAD-like helicase ; helicase domain protein; SPTR: DEAD/DEAH box helicase; PFAM: Helicase conserved C-terminal domain; DbpA RNA binding domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase complement(2492209..2493837) Spirochaeta smaragdinae DSM 11293 9490434 YP_003804038.1 CDS Spirs_2329 NC_014364.1 2493958 2494431 R InterPro IPR000182; KEGG: scb:SCAB_12821 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase complement(2493958..2494431) Spirochaeta smaragdinae DSM 11293 9490435 YP_003804039.1 CDS Spirs_2330 NC_014364.1 2494547 2494828 R COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504; KEGG: nis:NIS_0278 RNA-binding protein RNP-1; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: RNA-binding protein RNP-1; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); RNP-1 like RNA-binding protein complement(2494547..2494828) Spirochaeta smaragdinae DSM 11293 9490436 YP_003804040.1 CDS Spirs_2331 NC_014364.1 2495168 2497168 R COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR004807:IPR014001:IPR001650:IPR006935:IPR 001943:IPR014021; KEGG: tde:TDE1369 excinuclease ABC subunit B; PFAM: helicase domain protein; type III restriction protein res subunit; UvrB/UvrC protein; SMART: DEAD-like helicase ; helicase; SPTR: UvrABC system protein B; TIGRFAM: excinuclease ABC subunit B; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit; excinuclease ABC subunit B complement(2495168..2497168) Spirochaeta smaragdinae DSM 11293 9490437 YP_003804041.1 CDS Spirs_2332 NC_014364.1 2497187 2498419 R COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001940:IPR001254; KEGG: tde:TDE1966 trypsin domain/PDZ domain-containing protein; PFAM: peptidase S1 and S6 chymotrypsin/Hap; SPTR: Protease do; PFAM: Trypsin; peptidase S1 and S6 chymotrypsin/Hap complement(2497187..2498419) Spirochaeta smaragdinae DSM 11293 9490438 YP_003804042.1 CDS Spirs_2333 NC_014364.1 2498483 2500018 R COGs: COG0606 ATPase with chaperone activity; InterPro IPR001208:IPR003593:IPR000523:IPR004482; KEGG: tde:TDE1995 magnesium chelatase family protein; PFAM: magnesium chelatase ChlI subunit; SMART: ATPase AAA; SPTR: Magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein; Mg chelatase subunit ChlI complement(2498483..2500018) Spirochaeta smaragdinae DSM 11293 9490439 YP_003804043.1 CDS Spirs_2334 NC_014364.1 2500076 2500537 R COGs: COG0328 ribonuclease HI; InterPro IPR002156; KEGG: bid:Bind_2333 ribonuclease H; PFAM: ribonuclease H; SPTR: ribonuclease H; PFAM: RNase H; ribonuclease H complement(2500076..2500537) Spirochaeta smaragdinae DSM 11293 9490440 YP_003804044.1 CDS Spirs_2335 NC_014364.1 2500559 2502379 D COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR003959; KEGG: tde:TDE1329 ATPase AAA; PFAM: ATPase AAA central domain protein; SMART: ATPase AAA; SPTR: ATPase, AAA family; PFAM: ATPase family associated with various cellular activities (AAA); ATPase AAA 2500559..2502379 Spirochaeta smaragdinae DSM 11293 9490441 YP_003804045.1 CDS Spirs_2336 NC_014364.1 2502402 2503433 D COGs: COG2017 Galactose mutarotase; InterPro IPR018052:IPR008183; KEGG: psl:Psta_1401 aldose 1-epimerase; PFAM: aldose 1-epimerase; PRIAM: aldose 1-epimerase; SPTR: aldose 1-epimerase; PFAM: aldose 1-epimerase; aldose 1-epimerase 2502402..2503433 Spirochaeta smaragdinae DSM 11293 9490442 YP_003804046.1 CDS Spirs_2337 NC_014364.1 2503476 2504333 D COGs: COG1234 metal-dependent hydrolase of the beta-lactamase superfamily III; KEGG: gym:GYMC10_1899 beta-lactamase domain protein; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase 2503476..2504333 Spirochaeta smaragdinae DSM 11293 9490443 YP_003804047.1 CDS Spirs_2338 NC_014364.1 2504330 2505283 R COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR000825; KEGG: mba:Mbar_A3459 ABC transporter ATP-binding protein; PFAM: SufBD protein; SPTR: ABC transporter ATP-binding protein; PFAM: Uncharacterized protein family (UPF0051); SufBD protein complement(2504330..2505283) Spirochaeta smaragdinae DSM 11293 9490444 YP_003804048.1 CDS Spirs_2339 NC_014364.1 2505280 2506038 R COGs: COG0396 ABC-type transporter involved in Fe-S cluster assembly ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: mba:Mbar_A3458 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC; ABC transporter complement(2505280..2506038) Spirochaeta smaragdinae DSM 11293 9490445 YP_003804049.1 CDS Spirs_2340 NC_014364.1 2506042 2506608 R COGs: COG1437 adenylate cyclase class 2 (thermophilic); InterPro IPR008172:IPR008173; KEGG: bbz:BbuZS7_0747 adenylyl cyclase CyaB; PFAM: adenylate cyclase; SPTR: adenylyl cyclase CyaB; TIGRFAM: adenylyl cyclase CyaB; PFAM: CYTH domain; TIGRFAM: adenylyl cyclase CyaB; adenylyl cyclase CyaB complement(2506042..2506608) Spirochaeta smaragdinae DSM 11293 9490446 YP_003804050.1 CDS Spirs_2341 NC_014364.1 2506612 2507385 R KEGG: tpp:TPASS_0273 hypothetical protein; SPTR: membrane protein; hypothetical protein complement(2506612..2507385) Spirochaeta smaragdinae DSM 11293 9490447 YP_003804051.1 CDS Spirs_2342 NC_014364.1 2507418 2508695 R InterPro IPR011701; KEGG: kol:Kole_0459 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(2507418..2508695) Spirochaeta smaragdinae DSM 11293 9490448 YP_003804052.1 CDS Spirs_2343 NC_014364.1 2509045 2509617 R KEGG: glo:Glov_3710 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2509045..2509617) Spirochaeta smaragdinae DSM 11293 9490449 YP_003804053.1 CDS Spirs_2344 NC_014364.1 2510229 2511440 R InterPro IPR011701; KEGG: sit:TM1040_0869 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: tetracycline resistance protein TetA; manually curated; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(2510229..2511440) Spirochaeta smaragdinae DSM 11293 9490450 YP_003804054.1 CDS Spirs_2345 NC_014364.1 2511726 2512136 D COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: tde:TDE2225 thioesterase family protein; PFAM: thioesterase superfamily protein; SPTR: thioesterase family protein; PFAM: thioesterase; TIGRFAM: conserved hypothetical protein TIGR00051; thioesterase superfamily protein 2511726..2512136 Spirochaeta smaragdinae DSM 11293 9490452 YP_003804055.1 CDS Spirs_2346 NC_014364.1 2512140 2515058 R KEGG: tde:TDE1220 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2512140..2515058) Spirochaeta smaragdinae DSM 11293 9490453 YP_003804056.1 CDS Spirs_2347 NC_014364.1 2515106 2515639 D KEGG: hba:Hbal_0893 histidine kinase; SPTR: histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; hypothetical protein 2515106..2515639 Spirochaeta smaragdinae DSM 11293 9490454 YP_003804057.1 CDS Spirs_2348 NC_014364.1 2515642 2515986 D KEGG: cbr:CBG04479 Hypothetical protein CBG04479; SPTR: type IV pilus assembly protein PilZ; PFAM: PilZ domain; hypothetical protein 2515642..2515986 Spirochaeta smaragdinae DSM 11293 9490455 YP_003804058.1 CDS Spirs_2349 NC_014364.1 2515996 2517213 R InterPro IPR009875; KEGG: lic:LIC12723 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; PFAM: PilZ domain; type IV pilus assembly PilZ complement(2515996..2517213) Spirochaeta smaragdinae DSM 11293 9490456 YP_003804059.1 CDS Spirs_2350 NC_014364.1 2517188 2517802 R KEGG: hoh:Hoch_1821 SMC domain protein; SPTR: SMC domain protein; hypothetical protein complement(2517188..2517802) Spirochaeta smaragdinae DSM 11293 9490457 YP_003804060.1 CDS Spirs_2351 NC_014364.1 2517916 2519862 D COGs: COG1048 Aconitase A; InterPro IPR001030:IPR018136:IPR000573:IPR006250; KEGG: hmo:HM1_0105 aconitate hydratase, PFAM: aconitate hydratase domain protein; SPTR: Aconitase; TIGRFAM: aconitate hydratase; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, , Aquifex type; aconitate hydratase 2517916..2519862 Spirochaeta smaragdinae DSM 11293 9490458 YP_003804061.1 CDS Spirs_2352 NC_014364.1 2519862 2521139 D COGs: COG1078 HD superfamily phosphohydrolase; InterPro IPR003607:IPR006674; KEGG: tde:TDE1407 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; PFAM: HD domain; metal dependent phosphohydrolase 2519862..2521139 Spirochaeta smaragdinae DSM 11293 9490459 YP_003804062.1 CDS Spirs_2353 NC_014364.1 2521143 2521937 D COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063:IPR012089; KEGG: dal:Dalk_1237 PP-loop domain protein; PFAM: PP-loop domain protein; SPTR: PP-loop domain protein; PFAM: PP-loop family; PP-loop domain-containing protein 2521143..2521937 Spirochaeta smaragdinae DSM 11293 9490460 YP_003804063.1 CDS Spirs_2354 NC_014364.1 2521980 2522720 D InterPro IPR019657; KEGG: tde:TDE1406 hypothetical protein; PFAM: late competence development protein ComFB; SPTR: uncharacterized protein; PFAM: late competence development protein ComFB; late competence development protein ComFB 2521980..2522720 Spirochaeta smaragdinae DSM 11293 9490461 YP_003804064.1 CDS Spirs_2355 NC_014364.1 2522735 2523025 R COGs: COG1550 conserved hypothetical protein; InterPro IPR007546; KEGG: mta:Moth_1881 hypothetical protein; PFAM: protein of unknown function DUF503; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF503); hypothetical protein complement(2522735..2523025) Spirochaeta smaragdinae DSM 11293 9490462 YP_003804065.1 CDS Spirs_2356 NC_014364.1 2523036 2524157 R KEGG: bre:BRE_680 hypothetical protein; SPTR: uncharacterized protein; PFAM: ion transporter; hypothetical protein complement(2523036..2524157) Spirochaeta smaragdinae DSM 11293 9490463 YP_003804066.1 CDS Spirs_2357 NC_014364.1 2524160 2525077 R KEGG: bre:BRE_681 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2524160..2525077) Spirochaeta smaragdinae DSM 11293 9490464 YP_003804067.1 CDS Spirs_2358 NC_014364.1 2525158 2530008 D KEGG: sha:SH0326 hypothetical protein; SPTR: flagellar hook-length control protein fliK; hypothetical protein 2525158..2530008 Spirochaeta smaragdinae DSM 11293 9490465 YP_003804068.1 CDS Spirs_2359 NC_014364.1 2530111 2531466 D KEGG: cts:Ctha_0299 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2530111..2531466 Spirochaeta smaragdinae DSM 11293 9490466 YP_003804069.1 CDS Spirs_2360 NC_014364.1 2531481 2533724 D KEGG: cts:Ctha_0299 hypothetical protein; SPTR: uncharacterized protein; PFAM: FecR protein; hypothetical protein 2531481..2533724 Spirochaeta smaragdinae DSM 11293 9490467 YP_003804070.1 CDS Spirs_2361 NC_014364.1 2533737 2535578 D COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterProIPR014762:IPR003594:IPR013507:IPR014790:IPR 014763; KEGG: bhr:BH0211 DNA mismatch repair protein MutL; PFAM: DNA mismatch repair protein domain protein; ATP-binding region ATPase domain protein; MutL dimerisation; SPTR: DNA mismatch repair protein MutL; TIGRFAM: DNA mismatch repair protein MutL; PFAM: MutL C terminal dimerisation domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL; DNA mismatch repair protein MutL 2533737..2535578 Spirochaeta smaragdinae DSM 11293 9490468 YP_003804071.1 CDS Spirs_2362 NC_014364.1 2535649 2537592 R InterPro IPR019734:IPR001440:IPR013105:IPR013026; KEGG: tde:TDE1127 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein complement(2535649..2537592) Spirochaeta smaragdinae DSM 11293 9490469 YP_003804072.1 CDS Spirs_2363 NC_014364.1 2537611 2538336 R InterPro IPR019734:IPR001440:IPR013105:IPR013026; KEGG: tde:TDE1126 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein complement(2537611..2538336) Spirochaeta smaragdinae DSM 11293 9490470 YP_003804073.1 CDS Spirs_2364 NC_014364.1 2538419 2539780 D InterProIPR019734:IPR001440:IPR013105:IPR007560:IPR 013026; KEGG: tde:TDE1125 hypothetical protein; PFAM: restriction endonuclease; hypothetical protein; TPR repeat-containing protein; SPTR: TPR domain protein; PFAM: Restriction endonuclease; Tetratricopeptide repeat; restriction endonuclease 2538419..2539780 Spirochaeta smaragdinae DSM 11293 9490471 YP_003804074.1 CDS Spirs_2365 NC_014364.1 2539788 2540492 D KEGG: tde:TDE1124 hypothetical protein; SPTR: metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; hypothetical protein 2539788..2540492 Spirochaeta smaragdinae DSM 11293 9490472 YP_003804075.1 CDS Spirs_2366 NC_014364.1 2540489 2541424 D KEGG: hau:Haur_4010 hypothetical protein; SPTR: transcriptional regulator; hypothetical protein 2540489..2541424 Spirochaeta smaragdinae DSM 11293 9490473 YP_003804076.1 CDS Spirs_2367 NC_014364.1 2541398 2542114 R KEGG: tde:TDE1129 lipoprotein; SPTR: lipoprotein; hypothetical protein complement(2541398..2542114) Spirochaeta smaragdinae DSM 11293 9490474 YP_003804077.1 CDS Spirs_2368 NC_014364.1 2542098 2543261 R KEGG: hch:HCH_04194 acyltransferase; SPTR: Probable acyltransferase; acyltransferase complement(2542098..2543261) Spirochaeta smaragdinae DSM 11293 9490475 YP_003804078.1 CDS Spirs_2369 NC_014364.1 2543280 2543990 R COGs: COG0689 RNase PH; InterPro IPR018336:IPR001247:IPR015847:IPR002381; KEGG: pst:PSPTO_0077 ribonuclease PH; PFAM: 3' exoribonuclease; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: uncharacterized protein; TIGRFAM: ribonuclease PH; PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH; ribonuclease PH complement(2543280..2543990) Spirochaeta smaragdinae DSM 11293 9490476 YP_003804079.1 CDS Spirs_2370 NC_014364.1 2543990 2544379 R KEGG: rcu:RCOM_0517130 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2543990..2544379) Spirochaeta smaragdinae DSM 11293 9490477 YP_003804080.1 CDS Spirs_2371 NC_014364.1 2544430 2546676 R COGs: COG0826 Collagenase and related protease; InterPro IPR018039:IPR001539; KEGG: pca:Pcar_0064 collagenase-like protease; PFAM: peptidase U32; SPTR: peptidase U32; PFAM: Collagenase; peptidase family U32; peptidase U32 complement(2544430..2546676) Spirochaeta smaragdinae DSM 11293 9490478 YP_003804081.1 CDS Spirs_2372 NC_014364.1 2546734 2547429 R KEGG: tpa:TP0073 hypothetical protein; SPTR: HD domain protein; hypothetical protein complement(2546734..2547429) Spirochaeta smaragdinae DSM 11293 9490479 YP_003804082.1 CDS Spirs_2373 NC_014364.1 2547518 2548693 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR004358:IPR018488:IPR000595:IPR003661:IPR 003594:IPR005467; KEGG: dap:Dacet_2840 GAF sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; cyclic nucleotide-binding; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; Cyclic nucleotide-binding domain; histidine kinase complement(2547518..2548693) Spirochaeta smaragdinae DSM 11293 9490480 YP_003804083.1 CDS Spirs_2374 NC_014364.1 2548726 2549139 R COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: ddf:DEFDS_1845 hypothetical protein; PFAM: protein of unknown function UPF0047; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: conserved hypothetical protein TIGR00149; hypothetical protein complement(2548726..2549139) Spirochaeta smaragdinae DSM 11293 9490481 YP_003804084.1 CDS Spirs_2375 NC_014364.1 2549257 2550072 D COGs: COG0428 divalent heavy-metal cations transporter; InterPro IPR003689; KEGG: cbl:CLK_0612 ZIP family zinc transporter; PFAM: zinc/iron permease; SPTR: Zinc/iron permease; PFAM: ZIP Zinc transporter; zinc/iron permease 2549257..2550072 Spirochaeta smaragdinae DSM 11293 9490482 YP_003804085.1 CDS Spirs_2376 NC_014364.1 2550076 2551365 R KEGG: gwc:GWCH70_3440 N-6 DNA methylase; SPTR: N-6 DNA methylase; PFAM: type I restriction modification DNA specificity domain; hypothetical protein complement(2550076..2551365) Spirochaeta smaragdinae DSM 11293 9490483 YP_003804086.1 CDS Spirs_2377 NC_014364.1 2551417 2552025 R COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: mhu:Mhun_3032 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SPTR: IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain; phosphoribosylaminoimidazolecarboxamideformyltra nsferase complement(2551417..2552025) Spirochaeta smaragdinae DSM 11293 9490484 YP_003804087.1 CDS Spirs_2378 NC_014364.1 2552022 2553446 R COGs: COG0015 adenylosuccinate lyase; InterPro IPR000362:IPR003031:IPR020557; KEGG: tde:TDE1499 adenylosuccinate lyase, PFAM: fumarate lyase; SPTR: adenylosuccinate lyase, ; PFAM: Lyase; fumarate lyase complement(2552022..2553446) Spirochaeta smaragdinae DSM 11293 9490485 YP_003804088.1 CDS Spirs_2379 NC_014364.1 2553487 2555262 R COGs: COG1109 phosphomannomutase; InterProIPR005841:IPR016066:IPR005844:IPR005845:IPR 005846; KEGG: tde:TDE1998 phosphohexose mutase family protein; PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; SPTR: phosphoglucomutase/phosphomannomutase alpha/beta/subunit; PFAM: phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase, C-terminal domain; phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I complement(2553487..2555262) Spirochaeta smaragdinae DSM 11293 9490486 YP_003804089.1 CDS Spirs_2380 NC_014364.1 2555259 2555924 R COGs: COG0546 phosphatase; InterPro IPR005833:IPR005834:IPR006402:IPR006439; KEGG: cch:Cag_0976 HAD family hydrolase; PFAM: haloacid dehalogenase; SPTR: HAD-superfamily hydrolase subfamily IA; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; 2-phosphoglycolate phosphatase, prokaryotic; HAD-superfamily hydrolase complement(2555259..2555924) Spirochaeta smaragdinae DSM 11293 9490487 YP_003804090.1 CDS Spirs_2381 NC_014364.1 2555980 2556873 D COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678; KEGG: fsu:Fisuc_2273 Fmu (Sun) domain protein; PFAM: Fmu (Sun) domain protein; SPTR: Fmu (Sun) domain protein; PFAM: NOL1/NOP2/sun family; Fmu (Sun) domain-containing protein 2555980..2556873 Spirochaeta smaragdinae DSM 11293 9490488 YP_003804091.1 CDS Spirs_2382 NC_014364.1 2556914 2557393 D COGs: COG2426 membrane protein; InterPro IPR009577; KEGG: apo:Arcpr_0109 small multi-drug export; PFAM: small multi-drug export; SPTR: small multi-drug export; PFAM: small multi-drug export protein; small multi-drug export 2556914..2557393 Spirochaeta smaragdinae DSM 11293 9490489 YP_003804092.1 CDS Spirs_2383 NC_014364.1 2557401 2559413 D COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR014016:IPR014017; KEGG: tde:TDE0903 ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; SPTR: Helicase, UvrD/Rep family; PFAM: UvrD/REP helicase; UvrD/REP helicase 2557401..2559413 Spirochaeta smaragdinae DSM 11293 9490490 YP_003804093.1 CDS Spirs_2385 NC_014364.1 2561919 2562278 D KEGG: pcs:Pc13g11720 Pc13g11720; SPTR: uncharacterized protein; hypothetical protein 2561919..2562278 Spirochaeta smaragdinae DSM 11293 9490492 YP_003804094.1 CDS Spirs_2386 NC_014364.1 2562281 2563210 D COGs: COG0492 thioredoxin reductase; InterPro IPR000103:IPR013027:IPR000871:IPR008255; KEGG: chy:CHY_0560 thioredoxin/thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: thioredoxin-disulfide reductase; SPTR: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; thioredoxin-disulfide reductase 2562281..2563210 Spirochaeta smaragdinae DSM 11293 9490493 YP_003804095.1 CDS Spirs_2387 NC_014364.1 2563276 2564193 D InterPro IPR000620; KEGG: hoh:Hoch_5722 protein of unknown function DUF6 transmembrane; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family; hypothetical protein 2563276..2564193 Spirochaeta smaragdinae DSM 11293 9490494 YP_003804096.1 CDS Spirs_2388 NC_014364.1 2564213 2565010 R COGs: COG0084 Mg-dependent DNase; InterPro IPR018228:IPR001130:IPR012278:IPR015991; KEGG: aac:Aaci_0129 hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; SPTR: Hydrolase, TatD family; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; hydrolase, TatD family complement(2564213..2565010) Spirochaeta smaragdinae DSM 11293 9490495 YP_003804097.1 CDS Spirs_2389 NC_014364.1 2565389 2566171 D COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: syn:slr8026 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulatory protein; PFAM: MarR family; MarR family transcriptional regulator 2565389..2566171 Spirochaeta smaragdinae DSM 11293 9490497 YP_003804098.1 CDS Spirs_2390 NC_014364.1 2566390 2567289 D KEGG: csa:Csal_1702 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase, YhgA-like; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 2566390..2567289 Spirochaeta smaragdinae DSM 11293 9490498 YP_003804099.1 CDS Spirs_2391 NC_014364.1 2567499 2568194 R COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: rba:RB681 L-fuculose-phosphate aldolase; PFAM: class II aldolase/adducin family protein; SPTR: uncharacterized protein; PFAM: class II Aldolase and Adducin N-terminal domain; class II aldolase/adducin family protein complement(2567499..2568194) Spirochaeta smaragdinae DSM 11293 9490499 YP_003804100.1 CDS Spirs_2392 NC_014364.1 2568202 2569635 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: phe:Phep_3504 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(2568202..2569635) Spirochaeta smaragdinae DSM 11293 9490500 YP_003804101.1 CDS Spirs_2393 NC_014364.1 2569641 2570633 R COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: phe:Phep_3505 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase complement(2569641..2570633) Spirochaeta smaragdinae DSM 11293 9490501 YP_003804102.1 CDS Spirs_2394 NC_014364.1 2570641 2571708 R COGs: COG0182 translation initiation factor 2subunit beta eIF-2B alpha/beta/delta family; InterPro IPR000649:IPR011559; KEGG: ctc:CTC00945 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: translation initiation factor EIF-2subunit beta 1; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; eIF-2B alpha/beta/delta-like protein complement(2570641..2571708) Spirochaeta smaragdinae DSM 11293 9490502 YP_003804103.1 CDS Spirs_2395 NC_014364.1 2571795 2573006 R COGs: COG4857 kinase; InterPro IPR002575:IPR009212; KEGG: amt:Amet_3756 methylthioribose kinase; PFAM: aminoglycoside phosphotransferase; PRIAM: S-methyl-5-thioribose kinase; SPTR: uncharacterized protein; TIGRFAM: 5-methylthioribose kinase; PFAM: phosphotransferase enzyme family; TIGRFAM: 5-methylthioribose kinase; 5-methylthioribose kinase complement(2571795..2573006) Spirochaeta smaragdinae DSM 11293 9490503 YP_003804104.1 CDS Spirs_2396 NC_014364.1 2573010 2574344 R COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: fnu:FN1414 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: uncharacterized protein; PFAM: Na+/H+ antiporter family; Na+/H+ antiporter NhaC complement(2573010..2574344) Spirochaeta smaragdinae DSM 11293 9490504 YP_003804105.1 CDS Spirs_2397 NC_014364.1 2574842 2575615 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR018356:IPR014036; KEGG: csc:Csac_0990 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 2574842..2575615 Spirochaeta smaragdinae DSM 11293 9490505 YP_003804106.1 CDS Spirs_2398 NC_014364.1 2575631 2576797 D COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR018211:IPR001670; KEGG: sga:GALLO_2129 iron-containing alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 2575631..2576797 Spirochaeta smaragdinae DSM 11293 9490506 YP_003804107.1 CDS Spirs_2399 NC_014364.1 2577242 2577436 D KEGG: aac:Aaci_2951 hypothetical protein; SPTR: uncharacterized protein; manually curated; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 2577242..2577436 Spirochaeta smaragdinae DSM 11293 9490507 YP_003804108.1 CDS Spirs_2400 NC_014364.1 2577927 2578661 D KEGG: cpo:COPRO5265_1577 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2577927..2578661 Spirochaeta smaragdinae DSM 11293 9490508 YP_003804109.1 CDS Spirs_2401 NC_014364.1 2578974 2579708 R COGs: COG0363 6-phosphogluconolactonase/glucosamine-6-phosphate isomerase/deaminase; InterPro IPR018321:IPR006148; KEGG: bha:BH0420 N-acetylglucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; PRIAM: glucosamine-6-phosphate deaminase; SPTR: glucosamine-6-phosphate deaminase; PFAM: glucosamine-6-phosphate isomerases/6-phosphogluconolactonase; TIGRFAM: glucosamine-6-phosphate isomerase; glucosamine-6-phosphate deaminase complement(2578974..2579708) Spirochaeta smaragdinae DSM 11293 9490509 YP_003804110.1 CDS Spirs_2402 NC_014364.1 2579705 2580640 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tle:Tlet_0610 ROK family glucokinase; PFAM: ROK family protein; SPTR: glucokinase, ROK family; PFAM: ROK family; ROK family protein complement(2579705..2580640) Spirochaeta smaragdinae DSM 11293 9490510 YP_003804111.1 CDS Spirs_2403 NC_014364.1 2580637 2581878 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: mcl:MCCL_0359 NADH-dependent dehydrogenase family protein; PFAM: oxidoreductase domain protein; SPTR: NADH-dependent dehydrogenase family protein; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(2580637..2581878) Spirochaeta smaragdinae DSM 11293 9490511 YP_003804112.1 CDS Spirs_2404 NC_014364.1 2581896 2582747 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: cce:Ccel_3244 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2581896..2582747) Spirochaeta smaragdinae DSM 11293 9490512 YP_003804113.1 CDS Spirs_2405 NC_014364.1 2582737 2583615 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: cce:Ccel_3245 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2582737..2583615) Spirochaeta smaragdinae DSM 11293 9490513 YP_003804114.1 CDS Spirs_2406 NC_014364.1 2583685 2584986 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_3246 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2583685..2584986) Spirochaeta smaragdinae DSM 11293 9490514 YP_003804115.1 CDS Spirs_2407 NC_014364.1 2585033 2586175 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tit:Thit_0984 ROK family protein; PFAM: ROK family protein; SPTR: xylose repressor; PFAM: ROK family; ROK family protein complement(2585033..2586175) Spirochaeta smaragdinae DSM 11293 9490515 YP_003804116.1 CDS Spirs_2408 NC_014364.1 2586368 2587471 R COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: phe:Phep_0801 methicillin resistance protein; PFAM: methicillin resistance protein; SPTR: methicillin resistance protein; PFAM: FemAB family; methicillin resistance protein complement(2586368..2587471) Spirochaeta smaragdinae DSM 11293 9490516 YP_003804117.1 CDS Spirs_2409 NC_014364.1 2587556 2588206 D InterPro IPR013217; KEGG: drt:Dret_1150 methyltransferase type 12; PFAM: methyltransferase type 12; SPTR: methyltransferase type 12; manually curated; type 12 methyltransferase 2587556..2588206 Spirochaeta smaragdinae DSM 11293 9490517 YP_003804118.1 CDS Spirs_2410 NC_014364.1 2588254 2589036 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: drt:Dret_0475 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 2588254..2589036 Spirochaeta smaragdinae DSM 11293 9490518 YP_003804119.1 CDS Spirs_2411 NC_014364.1 2588994 2589749 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: drt:Dret_0476 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 2588994..2589749 Spirochaeta smaragdinae DSM 11293 9490519 YP_003804120.1 CDS Spirs_2412 NC_014364.1 2589805 2590656 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR018313:IPR001320:IPR001638; KEGG: dde:Dde_3070 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: extracellular solute-binding protein, family 3; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein 2589805..2590656 Spirochaeta smaragdinae DSM 11293 9490520 YP_003804121.1 CDS Spirs_2413 NC_014364.1 2590653 2591549 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: drt:Dret_0478 polar amino acid ABC transporter inner membrane subunit; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Polar amino acid ABC transporter inner membrane subunit; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 2590653..2591549 Spirochaeta smaragdinae DSM 11293 9490521 YP_003804122.1 CDS Spirs_2414 NC_014364.1 2591632 2593179 R COGs: COG0519 GMP synthase PP-ATPase domain/subunit; InterProIPR000991:IPR001962:IPR001674:IPR017926:IPR 004739; KEGG: aae:aq_236 GMP synthase; PFAM: GMP synthase domain protein; glutamine amidotransferase class-I; asparagine synthase; SPTR: GMP synthase; TIGRFAM: GMP synthase, large subunit; GMP synthase, small subunit; PFAM: GMP synthase C terminal domain; glutamine amidotransferase class-I; Asparagine synthase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or subunit beta; GMP synthase (glutamine-hydrolyzing), N-terminal domain or subunit alpha; GMP synthase, large subunit complement(2591632..2593179) Spirochaeta smaragdinae DSM 11293 9490522 YP_003804123.1 CDS Spirs_2415 NC_014364.1 2593164 2594393 R COGs: COG0104 adenylosuccinate synthase; InterPro IPR001114:IPR018220; KEGG: drm:Dred_3300 adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; PRIAM: adenylosuccinate synthase; SMART: adenylosuccinate synthetase; SPTR: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthetase; PFAM: adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase; adenylosuccinate synthetase complement(2593164..2594393) Spirochaeta smaragdinae DSM 11293 9490523 YP_003804124.1 CDS Spirs_2416 NC_014364.1 2594426 2596429 D InterPro IPR019734:IPR013105:IPR001440:IPR013026; KEGG: tde:TDE0043 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein 2594426..2596429 Spirochaeta smaragdinae DSM 11293 9490524 YP_003804125.1 CDS Spirs_2417 NC_014364.1 2596489 2597034 D KEGG: tde:TDE1944 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2596489..2597034 Spirochaeta smaragdinae DSM 11293 9490525 YP_003804126.1 CDS Spirs_2418 NC_014364.1 2597136 2599778 R COGs: COG0574 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; InterProIPR018274:IPR000121:IPR002192:IPR008279:IPR 010121; KEGG: tde:TDE0844 pyruvate phosphate dikinase; PFAM: PEP-utilizing protein; pyruvate phosphate dikinase PEP/pyruvate-binding; PEP-utilising protein mobile region; SPTR: pyruvate phosphate dikinase, ; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; TIGRFAM: pyruvate, phosphate dikinase; PEP-utilizing protein complement(2597136..2599778) Spirochaeta smaragdinae DSM 11293 9490526 YP_003804127.1 CDS Spirs_2419 NC_014364.1 2599795 2600832 R KEGG: tpp:TPASS_0747 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2599795..2600832) Spirochaeta smaragdinae DSM 11293 9490527 YP_003804128.1 CDS Spirs_2420 NC_014364.1 2600891 2602987 R KEGG: tde:TDE0842 cytoplasmic filament protein A; SPTR: Cytoplasmic filament protein A; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; cytoplasmic filament protein A complement(2600891..2602987) Spirochaeta smaragdinae DSM 11293 9490528 YP_003804129.1 CDS Spirs_2421 NC_014364.1 2603091 2604263 D InterPro IPR002035; KEGG: tde:TDE0841 hypothetical protein; PFAM: von Willebrand factor A; SMART: von Willebrand factor A; SPTR: uncharacterized protein; PFAM: von Willebrand factor A domain; von Willebrand factor A 2603091..2604263 Spirochaeta smaragdinae DSM 11293 9490529 YP_003804130.1 CDS Spirs_2422 NC_014364.1 2604268 2605272 D COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: sat:SYN_01784 phosphoesterase, DHH family protein; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; SPTR: phosphoesterase, DHH family protein; PFAM: DHHA1 domain; DHH family; phosphoesterase RecJ domain-containing protein 2604268..2605272 Spirochaeta smaragdinae DSM 11293 9490530 YP_003804131.1 CDS Spirs_2423 NC_014364.1 2605275 2606786 D KEGG: tde:TDE0840 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2605275..2606786 Spirochaeta smaragdinae DSM 11293 9490531 YP_003804132.1 CDS Spirs_2424 NC_014364.1 2606780 2607718 R InterPro IPR007730; KEGG: rme:Rmet_0097 sporulation related; PFAM: sporulation domain protein; SPTR: uncharacterized protein; PFAM: sporulation related domain; sporulation domain-containing protein complement(2606780..2607718) Spirochaeta smaragdinae DSM 11293 9490532 YP_003804133.1 CDS Spirs_2425 NC_014364.1 2607715 2608014 R KEGG: tde:TDE1615 hypothetical protein; SPTR: Conserved domain protein; hypothetical protein complement(2607715..2608014) Spirochaeta smaragdinae DSM 11293 9490533 YP_003804134.1 CDS Spirs_2426 NC_014364.1 2607999 2609321 R COGs: COG0621 2-methylthioadenine synthetase; InterProIPR006463:IPR006638:IPR013848:IPR007197:IPR 002792:IPR005839; KEGG: tde:TDE1576 (dimethylallyl)adenosine tRNA methylthiotransferase; PFAM: protein of unknown function UPF0004 ; radical SAM domain protein; deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: (dimethylallyl)adenosine tRNA methylthiotransferase miaB; TIGRFAM: tRNA-i(6)A37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; PFAM: TRAM domain; radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; RNA modification enzyme, MiaB family; tRNA-i(6)A37 thiotransferase protein MiaB complement(2607999..2609321) Spirochaeta smaragdinae DSM 11293 9490534 YP_003804135.1 CDS Spirs_2427 NC_014364.1 2609318 2611381 R COGs: COG1316 transcriptional regulator; InterPro IPR004474; KEGG: sro:Sros_1348 transcriptional regulator-like protein; PFAM: cell envelope-related transcriptional attenuator; SPTR: transcriptional regulator-like protein; TIGRFAM: cell envelope-related function transcriptional attenuator, LytR/CpsA family; PFAM: cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain; cell envelope-related transcriptional attenuator complement(2609318..2611381) Spirochaeta smaragdinae DSM 11293 9490535 YP_003804136.1 CDS Spirs_2428 NC_014364.1 2611391 2612638 R COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982:IPR002695; KEGG: dol:Dole_1516 phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme formylation region; PRIAM: phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme formylation region; SPTR: phosphoribosylaminoimidazolecarboxamide formyltransferase; PFAM: AICARFT/IMPCHase bienzyme; phosphoribosylaminoimidazolecarboxamideformyltra nsferase complement(2611391..2612638) Spirochaeta smaragdinae DSM 11293 9490536 YP_003804137.1 CDS Spirs_2429 NC_014364.1 2612680 2613576 R COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR000672:IPR020630:IPR020631; KEGG: ppd:Ppro_0480 methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methenyltetrahydrofolate cyclohydrolase; SPTR: Methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Methenyltetrahydrofolate cyclohydrolase complement(2612680..2613576) Spirochaeta smaragdinae DSM 11293 9490537 YP_003804138.1 CDS Spirs_2430 NC_014364.1 2613748 2614395 D KEGG: tde:TDE0014 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2613748..2614395 Spirochaeta smaragdinae DSM 11293 9490538 YP_003804139.1 CDS Spirs_2431 NC_014364.1 2614413 2615501 D KEGG: pub:SAR11_0932 hypothetical protein; SPTR: RTX toxin; hypothetical protein 2614413..2615501 Spirochaeta smaragdinae DSM 11293 9490539 YP_003804140.1 CDS Spirs_2432 NC_014364.1 2615528 2616718 R COGs: COG2208 serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001789:IPR001932:IPR010822; KEGG: cth:Cthe_0583 response regulator receiver protein; PFAM: stage II sporulation E family protein; response regulator receiver; SMART: protein phosphatase 2C domain protein; response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; stage II sporulation protein E (SpoIIE); response regulator receiver modulated serine phosphatase complement(2615528..2616718) Spirochaeta smaragdinae DSM 11293 9490540 YP_003804141.1 CDS Spirs_2433 NC_014364.1 2616835 2618754 D COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transporter; InterPro IPR004358:IPR003661:IPR003594:IPR005467; KEGG: csc:Csac_1328 response regulator receiver sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 2616835..2618754 Spirochaeta smaragdinae DSM 11293 9490541 YP_003804142.1 CDS Spirs_2434 NC_014364.1 2618747 2623444 R KEGG: pjd:Pjdr2_3565 S-layer domain protein; SPTR: S-layer domain protein; hypothetical protein complement(2618747..2623444) Spirochaeta smaragdinae DSM 11293 9490542 YP_003804143.1 CDS Spirs_2435 NC_014364.1 2623449 2624063 R COGs: COG2236 phosphoribosyltransferase; KEGG: bbz:BbuZS7_0103 phosphoribosyl transferase domain protein; SPTR: phosphoribosyl transferase domain protein; PFAM: phosphoribosyl transferase domain; phosphoribosyl transferase domain-containing protein complement(2623449..2624063) Spirochaeta smaragdinae DSM 11293 9490543 YP_003804144.1 CDS Spirs_2436 NC_014364.1 2624148 2625656 R COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001940:IPR001478:IPR001254:IPR011782; KEGG: tde:TDE2300 trypsin domain/PDZ domain-containing protein; PFAM: peptidase S1 and S6 chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF domain protein; SPTR: Trypsin domain/PDZ domain protein; TIGRFAM: protease Do; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF); TIGRFAM: periplasmic serine protease Do/DeqQ family; protease Do complement(2624148..2625656) Spirochaeta smaragdinae DSM 11293 9490544 YP_003804145.1 CDS Spirs_2437 NC_014364.1 2625671 2626432 R COGs: COG0024 methionine aminopeptidase; InterPro IPR001714:IPR002467:IPR000994; KEGG: tde:TDE1733 methionine aminopeptidase, type I; PFAM: peptidase M24; SPTR: methionine aminopeptidase; TIGRFAM: methionine aminopeptidase, type I; PFAM: metallopeptidase family M24; TIGRFAM: methionine aminopeptidase, type I; methionine aminopeptidase, type I complement(2625671..2626432) Spirochaeta smaragdinae DSM 11293 9490545 YP_003804146.1 CDS Spirs_2438 NC_014364.1 2626448 2628094 R InterPro IPR019734:IPR013026; KEGG: mma:MM_0103 O-linked N-acetylglucosamine transferase; SPTR: uncharacterized protein; hypothetical protein complement(2626448..2628094) Spirochaeta smaragdinae DSM 11293 9490546 YP_003804147.1 CDS Spirs_2439 NC_014364.1 2628091 2628513 R COGs: COG0781 transcription termination factor; InterPro IPR006027:IPR011605; KEGG: tpp:TPASS_1015 transcription antitermination protein NusB; PFAM: NusB/RsmB/TIM44; SPTR: transcription antitermination factor NusB; TIGRFAM: transcription antitermination factor NusB; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB; NusB antitermination factor complement(2628091..2628513) Spirochaeta smaragdinae DSM 11293 9490547 YP_003804148.1 CDS Spirs_2440 NC_014364.1 2628522 2629598 R InterPro IPR000297; KEGG: bre:BRE_110 basic membrane protein; PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; SPTR: Basic membrane protein; PFAM: SurA N-terminal domain; PPIC-type PPIASE domain; PpiC-type peptidyl-prolyl cis-trans isomerase complement(2628522..2629598) Spirochaeta smaragdinae DSM 11293 9490548 YP_003804149.1 CDS Spirs_2441 NC_014364.1 2629585 2630004 R KEGG: hor:Hore_18090 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2629585..2630004) Spirochaeta smaragdinae DSM 11293 9490549 YP_003804150.1 CDS Spirs_2442 NC_014364.1 2630065 2630418 R InterPro IPR004692; KEGG: tde:TDE1238 preprotein translocase subunit SecG; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase subunit SecG; TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit; preprotein translocase subunit SecG complement(2630065..2630418) Spirochaeta smaragdinae DSM 11293 9490550 YP_003804151.1 CDS Spirs_2443 NC_014364.1 2630438 2631187 R COGs: COG0149 triosephosphate isomerase; InterPro IPR020861:IPR000652; KEGG: tde:TDE1236 triosephosphate isomerase; PFAM: triosephosphate isomerase; PRIAM: triose-phosphate isomerase; SPTR: triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; PFAM: triosephosphate isomerase; TIGRFAM: triosephosphate isomerase; triosephosphate isomerase complement(2630438..2631187) Spirochaeta smaragdinae DSM 11293 9490551 YP_003804152.1 CDS Spirs_2444 NC_014364.1 2631187 2632374 R COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576:IPR015911; KEGG: bhr:BH0056 phosphoglycerate kinase; PFAM: phosphoglycerate kinase; PRIAM: phosphoglycerate kinase; SPTR: phosphoglycerate kinase; PFAM: phosphoglycerate kinase; phosphoglycerate kinase complement(2631187..2632374) Spirochaeta smaragdinae DSM 11293 9490552 YP_003804153.1 CDS Spirs_2445 NC_014364.1 2632387 2633388 R COGs: COG0057 glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterProIPR020832:IPR020830:IPR020828:IPR020829:IPR 020831:IPR006424; KEGG: bga:BG0056 glyceraldehyde 3-phosphate dehydrogenase; PFAM: glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SPTR: glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase; glyceraldehyde-3-phosphate dehydrogenase complement(2632387..2633388) Spirochaeta smaragdinae DSM 11293 9490553 YP_003804154.1 CDS Spirs_2446 NC_014364.1 2633461 2635497 R InterPro IPR019734:IPR013105:IPR001440:IPR013026; KEGG: tde:TDE1244 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein complement(2633461..2635497) Spirochaeta smaragdinae DSM 11293 9490554 YP_003804155.1 CDS Spirs_2447 NC_014364.1 2635478 2636263 R COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR005170; KEGG: tde:TDE1243 hemolysin C; PFAM: transporter-associated region; CBS domain containing protein; SPTR: Hemolysin C; PFAM: CBS domain; transporter associated domain; transport-associated protein complement(2635478..2636263) Spirochaeta smaragdinae DSM 11293 9490555 YP_003804156.1 CDS Spirs_2448 NC_014364.1 2636260 2636721 R COGs: COG0319 metal-dependent hydrolase; InterPro IPR020549:IPR002036; KEGG: tde:TDE1242 metalloprotease; PFAM: protein of unknown function UPF0054; SPTR: uncharacterized protein; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: conserved hypothetical protein TIGR00043; hypothetical protein complement(2636260..2636721) Spirochaeta smaragdinae DSM 11293 9490556 YP_003804157.1 CDS Spirs_2449 NC_014364.1 2636708 2638906 R COGs: COG1480 membrane-associated HD superfamily hydrolase; InterPro IPR011621:IPR006674:IPR006675:IPR003607; KEGG: tde:TDE1241 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; metal-dependent phosphohydrolase 7TM intracellular region; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: 7TM-HD extracellular; HD domain; 7TM receptor with intracellular HD hydrolase; TIGRFAM: uncharacterized domain HDIG; 7TM receptor with intracellular metal dependent phosphohydrolase complement(2636708..2638906) Spirochaeta smaragdinae DSM 11293 9490557 YP_003804158.1 CDS Spirs_2450 NC_014364.1 2638884 2639840 R COGs: COG1702 phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: tde:TDE1240 PhoH family protein; PFAM: PhoH family protein; SPTR: PhoH family protein; PFAM: PhoH-like protein; PhoH family protein complement(2638884..2639840) Spirochaeta smaragdinae DSM 11293 9490558 YP_003804159.1 CDS Spirs_2451 NC_014364.1 2639901 2643077 R COGs: COG1452 organic solvent tolerance protein OstA; KEGG: tde:TDE1011 hypothetical protein; SPTR: uncharacterized protein; organic solvent tolerance protein OstA complement(2639901..2643077) Spirochaeta smaragdinae DSM 11293 9490559 YP_003804160.1 CDS Spirs_2452 NC_014364.1 2643074 2645899 R COGs: COG0178 excinuclease ATPase; InterPro IPR017871:IPR003439:IPR004602; KEGG: tde:TDE1010 excinuclease ABC subunit A; PFAM: ABC transporter; SPTR: excinuclease ABC subunit A; TIGRFAM: excinuclease ABC subunit A; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, subunit alpha; excinuclease ABC subunit A complement(2643074..2645899) Spirochaeta smaragdinae DSM 11293 9490560 YP_003804161.1 CDS Spirs_2453 NC_014364.1 2645922 2646839 R InterPro IPR013026; KEGG: bhr:BH0089 tetratricopeptide repeat family protein; SPTR: Tetratricopeptide repeat family protein; hypothetical protein complement(2645922..2646839) Spirochaeta smaragdinae DSM 11293 9490561 YP_003804162.1 CDS Spirs_2454 NC_014364.1 2646860 2647903 R COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR004588; KEGG: tpp:TPASS_0446 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; PFAM: IspG family protein; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase complement(2646860..2647903) Spirochaeta smaragdinae DSM 11293 9490562 YP_003804163.1 CDS Spirs_2455 NC_014364.1 2647983 2648414 R KEGG: btu:BT0090 V-type ATP synthase subunit K; SPTR: V-type sodium ATP synthase subunit K; PFAM: ATP synthase subunit C; V-type ATP synthase subunit K complement(2647983..2648414) Spirochaeta smaragdinae DSM 11293 9490563 YP_003804164.1 CDS Spirs_2456 NC_014364.1 2648445 2650268 R COGs: COG1269 H+-ATPase I; InterPro IPR002490; KEGG: bbu:BB0091 V-type ATP synthase subunit I; PFAM: V-type ATPase 116 kDa subunit; SPTR: V-type ATP synthase subunit I; PFAM: V-type ATPase 116kDa subunit family; V-type ATPase 116 kDa subunit complement(2648445..2650268) Spirochaeta smaragdinae DSM 11293 9490564 YP_003804165.1 CDS Spirs_2457 NC_014364.1 2650271 2650867 R COGs: COG1394 H+-ATPase D; InterPro IPR002699; KEGG: bga:BG0093 V-type ATP synthase subunit D; PFAM: H+transporting two-sector ATPase D subunit; SPTR: uncharacterized protein; TIGRFAM: V-type ATPase, D subunit; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D; V-type ATPase subunit D complement(2650271..2650867) Spirochaeta smaragdinae DSM 11293 9490565 YP_003804166.1 CDS Spirs_2458 NC_014364.1 2650872 2652167 R COGs: COG1156 H+-ATPase B; InterPro IPR004100:IPR000194; KEGG: bre:BRE_95 V-type ATP synthase subunit B; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SPTR: V-type ATPase, subunit B; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; H+transporting two-sector ATPase alpha/subunit beta central region complement(2650872..2652167) Spirochaeta smaragdinae DSM 11293 9490566 YP_003804167.1 CDS Spirs_2459 NC_014364.1 2652186 2653952 R COGs: COG1155 H+-ATPase A; InterProIPR020003:IPR018089:IPR008265:IPR004100:IPR 000194; KEGG: tde:TDE1683 V-type ATP synthase subunit A; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SPTR: V-type ATP synthase alpha chain; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; H+transporting two-sector ATPase alpha/subunit beta central region complement(2652186..2653952) Spirochaeta smaragdinae DSM 11293 9490567 YP_003804168.1 CDS Spirs_2460 NC_014364.1 2653952 2654524 R KEGG: btu:BT0095 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2764); hypothetical protein complement(2653952..2654524) Spirochaeta smaragdinae DSM 11293 9490568 YP_003804169.1 CDS Spirs_2461 NC_014364.1 2654537 2655154 R KEGG: tde:TDE1381 V-type ATP synthase subunit E; SPTR: V-type ATP synthase subunit E; V-type ATP synthase subunit E complement(2654537..2655154) Spirochaeta smaragdinae DSM 11293 9490569 YP_003804170.1 CDS Spirs_2462 NC_014364.1 2655248 2655595 R KEGG: btl:BALH_3479 condensin subunit Smc; SPTR: chromosome partition protein smc; hypothetical protein complement(2655248..2655595) Spirochaeta smaragdinae DSM 11293 9490570 YP_003804171.1 CDS Spirs_2463 NC_014364.1 2655649 2656050 R KEGG: bhr:BH0097 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2655649..2656050) Spirochaeta smaragdinae DSM 11293 9490571 YP_003804172.1 CDS Spirs_2464 NC_014364.1 2656053 2656277 R KEGG: mmb:Mmol_1914 TonB-dependent siderophore receptor; SPTR: TonB-dependent siderophore receptor; hypothetical protein complement(2656053..2656277) Spirochaeta smaragdinae DSM 11293 9490572 YP_003804173.1 CDS Spirs_2465 NC_014364.1 2656274 2658676 R COGs: COG1193 Mismatch repair ATPase (MutS family); InterPro IPR000432:IPR002625:IPR005747:IPR007696; KEGG: tde:TDE1450 MutS2 family protein; PFAM: Smr protein/MutS2; DNA mismatch repair protein MutS domain protein; SMART: DNA mismatch repair protein MutS; MutS III domain protein; Smr protein/MutS2; SPTR: MutS2 protein; TIGRFAM: MutS2 family protein; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein; MutS2 family protein complement(2656274..2658676) Spirochaeta smaragdinae DSM 11293 9490573 YP_003804174.1 CDS Spirs_2466 NC_014364.1 2658652 2659614 R COGs: COG1162 GTPase; InterPro IPR004881:IPR010914; KEGG: tde:TDE1449 GTPase YjeQ; PFAM: GTPase EngC; SPTR: GTPase YjeQ; TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A; ribosome small subunit-dependent GTPase A complement(2658652..2659614) Spirochaeta smaragdinae DSM 11293 9490574 YP_003804175.1 CDS Spirs_2467 NC_014364.1 2659614 2660399 R COGs: COG0796 glutamate racemase; InterPro IPR018187:IPR015942:IPR004391; KEGG: tde:TDE1448 glutamate racemase, PFAM: Asp/Glu/hydantoin racemase; PRIAM: glutamate racemase; SPTR: glutamate racemase; TIGRFAM: glutamate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase; glutamate racemase complement(2659614..2660399) Spirochaeta smaragdinae DSM 11293 9490575 YP_003804176.1 CDS Spirs_2468 NC_014364.1 2660462 2661058 D COGs: COG1357 Uncharacterized low-complexity protein; InterPro IPR001646; KEGG: tde:TDE1228 pentapeptide repeat-containing protein; PFAM: pentapeptide repeat protein; SPTR: Pentapeptide repeat family protein; PFAM: Pentapeptide repeats (8 copies); pentapeptide repeat protein 2660462..2661058 Spirochaeta smaragdinae DSM 11293 9490576 YP_003804177.1 CDS Spirs_2469 NC_014364.1 2661055 2661678 D COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: tde:TDE1229 hypothetical protein; SPTR: GloB protein; PFAM: metallo-beta-lactamase superfamily; hypothetical protein 2661055..2661678 Spirochaeta smaragdinae DSM 11293 9490577 YP_003804178.1 CDS Spirs_2470 NC_014364.1 2661596 2662555 R COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006224:IPR006145:IPR006225; KEGG: bga:BG0018 hypothetical protein; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; TIGRFAM: pseudouridine synthase; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase; pseudouridine synthase complement(2661596..2662555) Spirochaeta smaragdinae DSM 11293 9490578 YP_003804179.1 CDS Spirs_2471 NC_014364.1 2662545 2662952 R KEGG: tde:TDE1081 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2662545..2662952) Spirochaeta smaragdinae DSM 11293 9490579 YP_003804180.1 CDS Spirs_2472 NC_014364.1 2662957 2663661 R COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: eca:ECA4047 alanine racemase; PFAM: alanine racemase domain protein; SPTR: alanine racemase; PFAM: alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family; alanine racemase domain-containing protein complement(2662957..2663661) Spirochaeta smaragdinae DSM 11293 9490580 YP_003804181.1 CDS Spirs_2473 NC_014364.1 2663746 2664537 D KEGG: tde:TDE2392 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2663746..2664537 Spirochaeta smaragdinae DSM 11293 9490581 YP_003804182.1 CDS Spirs_2474 NC_014364.1 2664577 2666022 D COGs: COG0786 Na+/glutamate symporter; KEGG: kol:Kole_1412 Na+/glutamate symporter-like protein; SPTR: Na+/glutamate symporter-like protein; Na+/glutamate symporter-like protein 2664577..2666022 Spirochaeta smaragdinae DSM 11293 9490582 YP_003804183.1 CDS Spirs_2475 NC_014364.1 2666253 2667515 D COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: bcy:Bcer98_2788 site-specific tyrosine recombinase XerD; PFAM: integrase family protein; SPTR: Tyrosine recombinase XerD; PFAM: Phage integrase family; integrase family protein 2666253..2667515 Spirochaeta smaragdinae DSM 11293 9490584 YP_003804184.1 CDS Spirs_2476 NC_014364.1 2667512 2667952 R InterPro IPR020136; KEGG: bam:Bamb_6598 hypothetical protein; SPTR: KorC protein; PFAM: Helix-turn-helix; hypothetical protein complement(2667512..2667952) Spirochaeta smaragdinae DSM 11293 9490585 YP_003804185.1 CDS Spirs_2477 NC_014364.1 2667949 2668332 R COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: tde:TDE0973 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: DNA repair protein; PFAM: protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; DNA repair protein RadC complement(2667949..2668332) Spirochaeta smaragdinae DSM 11293 9490586 YP_003804186.1 CDS Spirs_2479 NC_014364.1 2668815 2669231 R KEGG: cvi:CV_2409 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2668815..2669231) Spirochaeta smaragdinae DSM 11293 9490588 YP_003804187.1 CDS Spirs_2480 NC_014364.1 2669290 2669850 R KEGG: bfo:BRAFLDRAFT_85871 hypothetical protein; SPTR: SMI1/KNR4 family protein; hypothetical protein complement(2669290..2669850) Spirochaeta smaragdinae DSM 11293 9490589 YP_003804188.1 CDS Spirs_2481 NC_014364.1 2670085 2670474 R KEGG: pvx:PVX_095045 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2670085..2670474) Spirochaeta smaragdinae DSM 11293 9490590 YP_003804189.1 CDS Spirs_2482 NC_014364.1 2670476 2670724 R KEGG: tne:Tneu_0370 nucleoside recognition domain-containing protein; SPTR: UNC93-like protein MFSD11; hypothetical protein complement(2670476..2670724) Spirochaeta smaragdinae DSM 11293 9490591 YP_003804190.1 CDS Spirs_2483 NC_014364.1 2670721 2670822 R hypothetical protein complement(2670721..2670822) Spirochaeta smaragdinae DSM 11293 9490592 YP_003804191.1 CDS Spirs_2484 NC_014364.1 2670819 2671190 R KEGG: bdu:BDU_12007 BppB; SPTR: glycosyl transferase domain, group 2 family protein; hypothetical protein complement(2670819..2671190) Spirochaeta smaragdinae DSM 11293 9490593 YP_003804192.1 CDS Spirs_2485 NC_014364.1 2671197 2671430 R KEGG: tva:TVAG_483670 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2671197..2671430) Spirochaeta smaragdinae DSM 11293 9490594 YP_003804193.1 CDS Spirs_2486 NC_014364.1 2671435 2672046 R KEGG: bam:Bamb_1861 bacteriophage-acquired protein; SPTR: uncharacterized protein; hypothetical protein complement(2671435..2672046) Spirochaeta smaragdinae DSM 11293 9490595 YP_003804194.1 CDS Spirs_2487 NC_014364.1 2672043 2675357 R KEGG: bdu:BDU_2017 hypothetical protein; SPTR: Uncharacterized conserved protein; hypothetical protein complement(2672043..2675357) Spirochaeta smaragdinae DSM 11293 9490596 YP_003804195.1 CDS Spirs_2488 NC_014364.1 2675360 2677537 R KEGG: lif:LinJ14.1210 kinesin K39; SPTR: Kinesin K39; hypothetical protein complement(2675360..2677537) Spirochaeta smaragdinae DSM 11293 9490597 YP_003804196.1 CDS Spirs_2489 NC_014364.1 2677518 2677793 R KEGG: ote:Oter_4490 hypothetical protein; SPTR: Spermidine/putrescine ABC superfamily ATP binding cassette transporter binding protein; hypothetical protein complement(2677518..2677793) Spirochaeta smaragdinae DSM 11293 9490598 YP_003804197.1 CDS Spirs_2490 NC_014364.1 2677814 2678215 R KEGG: dmo:Dmoj_GI19584 GI19584 gene product from transcript GI19584-RA; SPTR: Sodium/sulfate symporter (ISS); hypothetical protein complement(2677814..2678215) Spirochaeta smaragdinae DSM 11293 9490599 YP_003804198.1 CDS Spirs_2491 NC_014364.1 2678218 2678910 R KEGG: pcb:PC101656.00.0 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2678218..2678910) Spirochaeta smaragdinae DSM 11293 9490600 YP_003804199.1 CDS Spirs_2492 NC_014364.1 2678912 2679310 R KEGG: ech:ECH_1012 DNA-binding response regulator; SPTR: response regulator component of a two-component regulatory system; hypothetical protein complement(2678912..2679310) Spirochaeta smaragdinae DSM 11293 9490601 YP_003804200.1 CDS Spirs_2493 NC_014364.1 2679288 2679713 R KEGG: dvm:DvMF_1651 hypothetical protein; SPTR: Phage protein, HK97 gp10 family; PFAM: bacteriophage protein of unknown function (DUF646); hypothetical protein complement(2679288..2679713) Spirochaeta smaragdinae DSM 11293 9490602 YP_003804201.1 CDS Spirs_2494 NC_014364.1 2679710 2680267 R KEGG: ngk:NGK_1435 phage associated protein; SPTR: uncharacterized protein; hypothetical protein complement(2679710..2680267) Spirochaeta smaragdinae DSM 11293 9490603 YP_003804202.1 CDS Spirs_2495 NC_014364.1 2680271 2680579 R KEGG: bfo:BRAFLDRAFT_97244 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2680271..2680579) Spirochaeta smaragdinae DSM 11293 9490604 YP_003804203.1 CDS Spirs_2496 NC_014364.1 2680638 2681888 R COGs: COG4653 phage phi-C31 gp36 major capsid-like protein; InterPro IPR006444; KEGG: pmy:Pmen_3970 HK97 family phage major capsid protein; PFAM: major capsid protein HK97; SPTR: Phage major capsid protein, HK97 family; TIGRFAM: phage major capsid protein, HK97 family; PFAM: Phage capsid family; TIGRFAM: phage major capsid protein, HK97 family; phage major capsid protein, HK97 family complement(2680638..2681888) Spirochaeta smaragdinae DSM 11293 9490605 YP_003804204.1 CDS Spirs_2497 NC_014364.1 2681903 2682610 R COGs: COG3740 Phage head maturation protease; InterPro IPR006433; KEGG: glo:Glov_1679 phage prohead protease HK97 family; PFAM: peptidase U35 phage prohead HK97; SPTR: Phage prohead protease HK97 family; TIGRFAM: phage prohead protease HK97 family; PFAM: Caudovirus prohead protease; TIGRFAM: phage prohead protease HK97 family; phage prohead protease HK97 family complement(2681903..2682610) Spirochaeta smaragdinae DSM 11293 9490606 YP_003804205.1 CDS Spirs_2498 NC_014364.1 2682607 2684223 R COGs: COG4695 Phage-related protein; InterPro IPR006944:IPR006427; KEGG: det:DET1087 HK97 family portal protein , PFAM: portal protein; SPTR: Phage portal protein, HK97 family; TIGRFAM: phage portal protein, HK97 family; PFAM: Phage portal protein; TIGRFAM: phage portal protein, HK97 family; phage portal protein, HK97 family complement(2682607..2684223) Spirochaeta smaragdinae DSM 11293 9490607 YP_003804206.1 CDS Spirs_2499 NC_014364.1 2684220 2685944 R COGs: COG4626 Phage terminase-like protein large subunit; InterPro IPR005021; KEGG: pag:PLES_25381 terminase; PFAM: terminase; SPTR: terminase; PFAM: Phage terminase; terminase complement(2684220..2685944) Spirochaeta smaragdinae DSM 11293 9490608 YP_003804207.1 CDS Spirs_2500 NC_014364.1 2685941 2686450 R COGs: COG3747 Phage terminase small subunit; InterPro IPR006448; KEGG: spa:M6_Spy1142 phage terminase small subunit; PFAM: terminase small subunit P27; SPTR: Phage terminase Small Subunit; TIGRFAM: phage terminase, small subunit, , P27 family; PFAM: Phage terminase, small subunit; TIGRFAM: phage terminase, small subunit, , P27 family; phage terminase, small subunit, , P27 family complement(2685941..2686450) Spirochaeta smaragdinae DSM 11293 9490609 YP_003804208.1 CDS Spirs_2501 NC_014364.1 2686454 2686852 R KEGG: dvu:DVU1505 holin, SPTR: Holin; hypothetical protein complement(2686454..2686852) Spirochaeta smaragdinae DSM 11293 9490610 YP_003804209.1 CDS Spirs_2502 NC_014364.1 2687097 2687804 R InterPro IPR002500; KEGG: sal:Sala_0768 phosphoadenosine phosphosulfate reductase; PFAM: phosphoadenosine phosphosulfate reductase; SPTR: uncharacterized protein; PFAM: phosphoadenosine phosphosulfate reductase family; phosphoadenosine phosphosulfate reductase complement(2687097..2687804) Spirochaeta smaragdinae DSM 11293 9490611 YP_003804210.1 CDS Spirs_2503 NC_014364.1 2687794 2688030 R KEGG: str:Sterm_4041 ROK family protein; SPTR: ROK family protein; hypothetical protein complement(2687794..2688030) Spirochaeta smaragdinae DSM 11293 9490612 YP_003804211.1 CDS Spirs_2504 NC_014364.1 2688024 2688701 R KEGG: rer:pREL1_0087 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2688024..2688701) Spirochaeta smaragdinae DSM 11293 9490613 YP_003804212.1 CDS Spirs_2505 NC_014364.1 2688698 2689612 R KEGG: xce:Xcel_3395 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2688698..2689612) Spirochaeta smaragdinae DSM 11293 9490614 YP_003804213.1 CDS Spirs_2506 NC_014364.1 2689612 2689965 R KEGG: ncr:NCU06443 hypothetical protein; SPTR: Predicted protein; hypothetical protein complement(2689612..2689965) Spirochaeta smaragdinae DSM 11293 9490615 YP_003804214.1 CDS Spirs_2507 NC_014364.1 2689910 2690722 R KEGG: rfr:Rfer_4353 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: CRISPR-associated protein, Csf1 family; hypothetical protein complement(2689910..2690722) Spirochaeta smaragdinae DSM 11293 9490616 YP_003804215.1 CDS Spirs_2508 NC_014364.1 2690719 2690898 R KEGG: sce:YIL157C Coa1p; hypothetical protein complement(2690719..2690898) Spirochaeta smaragdinae DSM 11293 9490617 YP_003804216.1 CDS Spirs_2509 NC_014364.1 2690927 2691118 R hypothetical protein complement(2690927..2691118) Spirochaeta smaragdinae DSM 11293 9490618 YP_003804217.1 CDS Spirs_2510 NC_014364.1 2691115 2691333 R hypothetical protein complement(2691115..2691333) Spirochaeta smaragdinae DSM 11293 9490619 YP_003804218.1 CDS Spirs_2511 NC_014364.1 2691317 2691718 R KEGG: drm:Dred_3054 hypothetical protein; SPTR: ATP-binding protein; hypothetical protein complement(2691317..2691718) Spirochaeta smaragdinae DSM 11293 9490620 YP_003804219.1 CDS Spirs_2512 NC_014364.1 2691723 2692811 R KEGG: ate:Athe_2433 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2691723..2692811) Spirochaeta smaragdinae DSM 11293 9490621 YP_003804220.1 CDS Spirs_2513 NC_014364.1 2692824 2693420 R COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: tde:TDE1677 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein complement(2692824..2693420) Spirochaeta smaragdinae DSM 11293 9490622 YP_003804221.1 CDS Spirs_2514 NC_014364.1 2693430 2693843 R KEGG: bfr:BF2472 recombination protein; SPTR: uncharacterized protein; PFAM: bacteriophage Lambda NinG protein; hypothetical protein complement(2693430..2693843) Spirochaeta smaragdinae DSM 11293 9490623 YP_003804222.1 CDS Spirs_2515 NC_014364.1 2693840 2696353 R InterPro IPR002941:IPR014001:IPR014021:IPR001091; KEGG: slt:Slit_1937 DNA methylase N-4/N-6 domain protein; PFAM: DNA methylase N-4/N-6 domain protein; SMART: DEAD-like helicase; SPTR: uncharacterized protein; PFAM: DNA methylase; SNF2 family N-terminal domain; DNA methylase N-4/N-6 domain-containing protein complement(2693840..2696353) Spirochaeta smaragdinae DSM 11293 9490624 YP_003804223.1 CDS Spirs_2516 NC_014364.1 2696356 2696832 R KEGG: mka:MK1283 hypothetical protein; SPTR: Fusion of at least two uncharacterized domain specific for M.kandleri, MK-2 family; hypothetical protein complement(2696356..2696832) Spirochaeta smaragdinae DSM 11293 9490625 YP_003804224.1 CDS Spirs_2517 NC_014364.1 2696829 2697434 R KEGG: bvi:Bcep1808_4494 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2696829..2697434) Spirochaeta smaragdinae DSM 11293 9490626 YP_003804225.1 CDS Spirs_2518 NC_014364.1 2697453 2698319 R InterPro IPR018330:IPR010183; KEGG: hth:HTH_0517 phage recombination protein; PFAM: DNA single-strand annealing protein RecT-like; SPTR: Phage recombination protein; TIGRFAM: phage recombination protein Bet; PFAM: RecT family; TIGRFAM: phage recombination protein Bet; phage recombination protein Bet complement(2697453..2698319) Spirochaeta smaragdinae DSM 11293 9490627 YP_003804226.1 CDS Spirs_2519 NC_014364.1 2698316 2698585 R KEGG: ath:AT1G13730 nuclear transport factor 2 (NTF2) family protein / RNA recognition motif (RRM)-containing protein; SPTR: At1g13730; hypothetical protein complement(2698316..2698585) Spirochaeta smaragdinae DSM 11293 9490628 YP_003804227.1 CDS Spirs_2520 NC_014364.1 2699141 2699344 R KEGG: sen:SACE_3576 integral membrane protein MviN; SPTR: integral membrane protein MviN; hypothetical protein complement(2699141..2699344) Spirochaeta smaragdinae DSM 11293 9490629 YP_003804228.1 CDS Spirs_2521 NC_014364.1 2699404 2700138 R KEGG: lsl:LSL_0261 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2699404..2700138) Spirochaeta smaragdinae DSM 11293 9490630 YP_003804229.1 CDS Spirs_2522 NC_014364.1 2700139 2700486 R KEGG: ctc:CTC02140 hypothetical protein; SPTR: Phage protein; hypothetical protein complement(2700139..2700486) Spirochaeta smaragdinae DSM 11293 9490631 YP_003804230.1 CDS Spirs_2523 NC_014364.1 2700598 2700861 R KEGG: aag:AaeL_AAEL001196 cadherin; SPTR: cadherin; hypothetical protein complement(2700598..2700861) Spirochaeta smaragdinae DSM 11293 9490633 YP_003804231.1 CDS Spirs_2524 NC_014364.1 2700891 2701232 D InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator 2700891..2701232 Spirochaeta smaragdinae DSM 11293 9490634 YP_003804232.1 CDS Spirs_2525 NC_014364.1 2701372 2701794 R KEGG: ptm:GSPATT00016699001 hypothetical protein; SPTR: chromosome undetermined scaffold_49, whole genome shotgun sequence; hypothetical protein complement(2701372..2701794) Spirochaeta smaragdinae DSM 11293 9490635 YP_003804233.1 CDS Spirs_2526 NC_014364.1 2702057 2702443 D KEGG: tde:TDE1170 DNA-binding protein; SPTR: DNA-binding protein; PFAM: bacteriophage CI repressor helix-turn-helix domain; DNA-binding protein 2702057..2702443 Spirochaeta smaragdinae DSM 11293 9490636 YP_003804234.1 CDS Spirs_2527 NC_014364.1 2702566 2703069 D InterPro IPR007527; KEGG: dps:DP0510 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2702566..2703069 Spirochaeta smaragdinae DSM 11293 9490637 YP_003804235.1 CDS Spirs_2528 NC_014364.1 2703117 2703407 D KEGG: nhl:Nhal_1282 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2703117..2703407 Spirochaeta smaragdinae DSM 11293 9490638 YP_003804236.1 CDS Spirs_2529 NC_014364.1 2703410 2703772 D KEGG: ttr:Tter_1991 binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; hypothetical protein 2703410..2703772 Spirochaeta smaragdinae DSM 11293 9490639 YP_003804237.1 CDS Spirs_2530 NC_014364.1 2704208 2704579 R KEGG: gau:GAU_2696 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2704208..2704579) Spirochaeta smaragdinae DSM 11293 9490640 YP_003804238.1 CDS Spirs_2531 NC_014364.1 2705439 2706107 D KEGG: mcp:MCAP_0049 DNA adenine methylase; SPTR: ggdef domain protein; hypothetical protein 2705439..2706107 Spirochaeta smaragdinae DSM 11293 9490641 YP_003804239.1 CDS Spirs_2532 NC_014364.1 2706104 2707753 R COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: kko:Kkor_0171 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase/phosphodiesterase complement(2706104..2707753) Spirochaeta smaragdinae DSM 11293 9490642 YP_003804240.1 CDS Spirs_2533 NC_014364.1 2707887 2708216 D KEGG: cpy:Cphy_2226 thiol-disulfide isomerase and thioredoxin; SPTR: thiol-disulfide isomerase and thioredoxin; PFAM: thioredoxin; thiol-disulfide isomerase and thioredoxin 2707887..2708216 Spirochaeta smaragdinae DSM 11293 9490643 YP_003804241.1 CDS Spirs_2534 NC_014364.1 2708278 2710314 D COGs: COG0480 translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 004540:IPR005225; KEGG: tde:TDE0285 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain protein; SPTR: translation elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; translation elongation factor G 2708278..2710314 Spirochaeta smaragdinae DSM 11293 9490644 YP_003804242.1 CDS Spirs_2535 NC_014364.1 2710327 2711289 D InterPro IPR004776; KEGG: lpj:JDM1_0536 malate transport protein; PFAM: hypothetical protein; SPTR: uncharacterized protein; PFAM: membrane transporter; hypothetical protein 2710327..2711289 Spirochaeta smaragdinae DSM 11293 9490645 YP_003804243.1 CDS Spirs_2536 NC_014364.1 2711388 2713469 D COGs: COG0480 translation elongation factors (GTPase); InterProIPR001252:IPR000795:IPR004161:IPR005517:IPR 000640:IPR005225; KEGG: tde:TDE0947 translation elongation factor G, PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain protein; SPTR: translation elongation factor G, ; TIGRFAM: small GTP-binding protein; PFAM: Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; small GTP-binding protein 2711388..2713469 Spirochaeta smaragdinae DSM 11293 9490646 YP_003804244.1 CDS Spirs_2537 NC_014364.1 2713516 2714868 R COGs: COG0372 citrate synthase; InterPro IPR002020; KEGG: mta:Moth_1122 citrate synthase; PFAM: citrate synthase; SPTR: citrate (Si)-synthase; PFAM: citrate synthase; citrate synthase complement(2713516..2714868) Spirochaeta smaragdinae DSM 11293 9490647 YP_003804245.1 CDS Spirs_2538 NC_014364.1 2714953 2715630 R COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; InterPro IPR003358; KEGG: rpi:Rpic_0653 tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; SPTR: tRNA (Guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; PFAM: methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase; tRNA (guanine-N(7)-)-methyltransferase complement(2714953..2715630) Spirochaeta smaragdinae DSM 11293 9490648 YP_003804246.1 CDS Spirs_2539 NC_014364.1 2715644 2717848 R COGs: COG3605 Signal transduction protein containing GAF and PtsI domains; InterProIPR000121:IPR003018:IPR008731:IPR008279:IPR 006318; KEGG: dat:HRM2_44960 Pdp; PFAM: PEP-utilizing protein; GAF domain protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; SMART: GAF domain protein; SPTR: Pdp; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: GAF domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PTSINtr with GAF domain, PtsP complement(2715644..2717848) Spirochaeta smaragdinae DSM 11293 9490649 YP_003804247.1 CDS Spirs_2540 NC_014364.1 2717865 2721251 R COGs: COG1197 transcription-repair coupling factor (superfamily II helicase); InterProIPR003711:IPR011545:IPR001650:IPR005118:IPR 004576:IPR014001:IPR014021; KEGG: tde:TDE1287 transcription-repair coupling factor; PFAM: transcription factor CarD; DEAD/DEAH box helicase domain protein; helicase; TRCF domain protein; SMART: DEAD-like helicase ; helicase; SPTR: transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd); transcription-repair coupling factor complement(2717865..2721251) Spirochaeta smaragdinae DSM 11293 9490650 YP_003804248.1 CDS Spirs_2541 NC_014364.1 2721293 2722234 D KEGG: tde:TDE1089 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2721293..2722234 Spirochaeta smaragdinae DSM 11293 9490651 YP_003804249.1 CDS Spirs_2542 NC_014364.1 2722236 2722967 D InterPro IPR009875; KEGG: tde:TDE1088 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; type IV pilus assembly PilZ 2722236..2722967 Spirochaeta smaragdinae DSM 11293 9490652 YP_003804250.1 CDS Spirs_2543 NC_014364.1 2723278 2723658 D KEGG: dal:Dalk_1712 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2723278..2723658 Spirochaeta smaragdinae DSM 11293 9490653 YP_003804251.1 CDS Spirs_2544 NC_014364.1 2723648 2724661 D COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR016431; KEGG: kol:Kole_1694 radical SAM domain protein; PFAM: radical SAM protein; SPTR: radical SAM domain protein; manually curated; PFAM: radical SAM superfamily; radical SAM protein 2723648..2724661 Spirochaeta smaragdinae DSM 11293 9490654 YP_003804252.1 CDS Spirs_2546 NC_014364.1 2725630 2725884 D KEGG: car:cauri_0776 hypothetical protein; SPTR: alpha subunit of RNA polymerase; hypothetical protein 2725630..2725884 Spirochaeta smaragdinae DSM 11293 9490658 YP_003804253.1 CDS Spirs_2547 NC_014364.1 2726004 2727188 R KEGG: cpv:cgd3_770 ULP1 like protease with a chlamydin like cysteine protease domain; SPTR: ULP1 like protease with a chlamydin like cysteine protease domain; hypothetical protein complement(2726004..2727188) Spirochaeta smaragdinae DSM 11293 9490659 YP_003804254.1 CDS Spirs_2548 NC_014364.1 2727172 2728890 R COGs: COG1680 beta-lactamase class C and other penicillin binding protein; InterPro IPR001466; KEGG: gme:Gmet_1507 beta-lactamase; PFAM: beta-lactamase; SPTR: beta-lactamase; PFAM: beta-lactamase; beta-lactamase complement(2727172..2728890) Spirochaeta smaragdinae DSM 11293 9490660 YP_003804255.1 CDS Spirs_2549 NC_014364.1 2729018 2729890 R InterPro IPR000792; KEGG: chu:CHU_1181 response regulator, positive activator of UhpT transcription; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Response regulator, positive activator of uhpT transcription; PFAM: Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(2729018..2729890) Spirochaeta smaragdinae DSM 11293 9490661 YP_003804256.1 CDS Spirs_2550 NC_014364.1 2730227 2730457 R KEGG: ilo:IL0593 hypothetical protein; SPTR: Uncharacterized conserved protein; hypothetical protein complement(2730227..2730457) Spirochaeta smaragdinae DSM 11293 9490662 YP_003804257.1 CDS Spirs_2551 NC_014364.1 2730931 2731527 D COGs: COG2342 extracellular endo alpha-1 4 polygalactosaminidase or related polysaccharide hydrolase; InterPro IPR004352; KEGG: smf:Smon_1000 TM1410 hypothetical-related protein; PFAM: TM1410 hypothetical-related protein; SPTR: uncharacterized protein; PFAM: TM1410 hypothetical-related protein; hypothetical protein 2730931..2731527 Spirochaeta smaragdinae DSM 11293 9490663 YP_003804258.1 CDS Spirs_2553 NC_014364.1 2732557 2732754 D KEGG: bvu:BVU_0247 hypothetical protein; hypothetical protein 2732557..2732754 Spirochaeta smaragdinae DSM 11293 9490665 YP_003804259.1 CDS Spirs_2554 NC_014364.1 2733568 2734539 D InterPro IPR013247:IPR003646; KEGG: cpr:CPR_A0006 bacteriocin; PFAM: SH3 type 3 domain protein; SMART: SH3 domain protein; SPTR: uncharacterized protein; PFAM: Bacterial SH3 domain; SH3 type 3 domain-containing protein 2733568..2734539 Spirochaeta smaragdinae DSM 11293 9490666 YP_003804260.1 CDS Spirs_2556 NC_014364.1 2735109 2735840 R InterPro IPR010540; KEGG: cbe:Cbei_1026 hypothetical protein; PFAM: protein of unknown function DUF1113; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1113); hypothetical protein complement(2735109..2735840) Spirochaeta smaragdinae DSM 11293 9490668 YP_003804261.1 CDS Spirs_2557 NC_014364.1 2735940 2737139 R KEGG: scl:sce0684 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2735940..2737139) Spirochaeta smaragdinae DSM 11293 9490669 YP_003804262.1 CDS Spirs_2558 NC_014364.1 2737443 2737811 R COGs: COG2164 conserved hypothetical protein; InterPro IPR007256; KEGG: tye:THEYE_A0257 hypothetical protein; PFAM: protein of unknown function DUF369; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF369); hypothetical protein complement(2737443..2737811) Spirochaeta smaragdinae DSM 11293 9490670 YP_003804263.1 CDS Spirs_2559 NC_014364.1 2737827 2739848 R KEGG: gym:GYMC10_3557 hypothetical protein; SPTR: uncharacterized protein; PFAM: beta-galactosidase trimerisation domain; hypothetical protein complement(2737827..2739848) Spirochaeta smaragdinae DSM 11293 9490671 YP_003804264.1 CDS Spirs_2560 NC_014364.1 2739872 2740900 R COGs: COG2055 malate/L-lactate dehydrogenase; InterPro IPR003767; KEGG: afv:AFLA_065330 malate dehydrogenase, PFAM: malate/L-lactate dehydrogenase; SPTR: malate/L-lactate dehydrogenases; PFAM: malate/L-lactate dehydrogenase; malate/L-lactate dehydrogenase complement(2739872..2740900) Spirochaeta smaragdinae DSM 11293 9490672 YP_003804265.1 CDS Spirs_2561 NC_014364.1 2740933 2742981 R KEGG: gym:GYMC10_3553 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2740933..2742981) Spirochaeta smaragdinae DSM 11293 9490673 YP_003804266.1 CDS Spirs_2562 NC_014364.1 2743017 2744204 R COGs: COG0282 acetate kinase; InterPro IPR000890:IPR004372; KEGG: psl:Psta_3282 acetate kinase; PFAM: acetate and butyrate kinase; SPTR: acetate kinase; TIGRFAM: acetate kinase; PFAM: acetokinase family; TIGRFAM: acetate kinase; acetate kinase complement(2743017..2744204) Spirochaeta smaragdinae DSM 11293 9490674 YP_003804267.1 CDS Spirs_2563 NC_014364.1 2744248 2745129 R COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR002204:IPR006115:IPR006398:IPR006183; KEGG: dda:Dd703_0845 2-hydroxy-3-oxopropionate reductase; PFAM: 6-phosphogluconate dehydrogenase NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; TIGRFAM: 2-hydroxy-3-oxopropionate reductase; 2-hydroxy-3-oxopropionate reductase complement(2744248..2745129) Spirochaeta smaragdinae DSM 11293 9490675 YP_003804268.1 CDS Spirs_2564 NC_014364.1 2745126 2745710 R COGs: COG2091 phosphopantetheinyl transferase; InterPro IPR008278; KEGG: bcr:BCAH187_C0026 4'-phosphopantetheinyl transferase, CesP; PFAM: 4'-phosphopantetheinyl transferase; SPTR: uncharacterized protein; PFAM: 4'-phosphopantetheinyl transferase superfamily; 4'-phosphopantetheinyl transferase complement(2745126..2745710) Spirochaeta smaragdinae DSM 11293 9490676 YP_003804269.1 CDS Spirs_2565 NC_014364.1 2745765 2745944 R KEGG: amt:Amet_0688 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2745765..2745944) Spirochaeta smaragdinae DSM 11293 9490677 YP_003804270.1 CDS Spirs_2566 NC_014364.1 2745937 2747493 R COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR010429; KEGG: eum:ECUMN_0359 enzyme with acyl-CoA domain; PFAM: FdrA family protein; SPTR: enzyme with acyl-CoA domain; PFAM: CoA binding domain; CoA-ligase; FdrA family protein complement(2745937..2747493) Spirochaeta smaragdinae DSM 11293 9490678 YP_003804271.1 CDS Spirs_2567 NC_014364.1 2747495 2748748 R InterPro IPR009499; KEGG: mta:Moth_2121 hypothetical protein; PFAM: protein of unknown function DUF1116; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1116); hypothetical protein complement(2747495..2748748) Spirochaeta smaragdinae DSM 11293 9490679 YP_003804272.1 CDS Spirs_2568 NC_014364.1 2748806 2749756 R COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterPro IPR003439:IPR013563:IPR010066:IPR003593; KEGG: fnu:FN0400 peptide ABC transporter ATP-binding protein; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide transport ATP-binding protein OppF; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; oligopeptide/dipeptide ABC transporter ATPase complement(2748806..2749756) Spirochaeta smaragdinae DSM 11293 9490680 YP_003804273.1 CDS Spirs_2569 NC_014364.1 2749759 2750742 R COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003439:IPR013563:IPR010066:IPR 003593; KEGG: fnu:FN0399 peptide ABC transporter ATP-binding protein; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: AAA ATPase; SPTR: uncharacterized protein; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; oligopeptide/dipeptide ABC transporter ATPase complement(2749759..2750742) Spirochaeta smaragdinae DSM 11293 9490681 YP_003804274.1 CDS Spirs_2570 NC_014364.1 2750754 2751641 R COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: fnu:FN0398 peptide ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2750754..2751641) Spirochaeta smaragdinae DSM 11293 9490682 YP_003804275.1 CDS Spirs_2571 NC_014364.1 2751662 2752591 R COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: aoe:Clos_1348 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transport system inner membrane component; binding-protein-dependent transporters inner membrane component complement(2751662..2752591) Spirochaeta smaragdinae DSM 11293 9490683 YP_003804276.1 CDS Spirs_2572 NC_014364.1 2752572 2752685 R hypothetical protein complement(2752572..2752685) Spirochaeta smaragdinae DSM 11293 9490684 YP_003804277.1 CDS Spirs_2573 NC_014364.1 2752716 2754284 R COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: fnu:FN0396 dipeptide-binding protein; PFAM: extracellular solute-binding protein family 5; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein complement(2752716..2754284) Spirochaeta smaragdinae DSM 11293 9490685 YP_003804278.1 CDS Spirs_2574 NC_014364.1 2754304 2755272 R COGs: COG1052 lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: amt:Amet_2953 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: uncharacterized protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase complement(2754304..2755272) Spirochaeta smaragdinae DSM 11293 9490686 YP_003804279.1 CDS Spirs_2575 NC_014364.1 2755285 2756391 R InterPro IPR012307; KEGG: csc:Csac_0350 xylose isomerase domain-containing protein; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: uncharacterized protein; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase complement(2755285..2756391) Spirochaeta smaragdinae DSM 11293 9490687 YP_003804280.1 CDS Spirs_2576 NC_014364.1 2756534 2757214 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: cpy:Cphy_1313 regulatory protein GntR HTH; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 2756534..2757214 Spirochaeta smaragdinae DSM 11293 9490688 YP_003804281.1 CDS Spirs_2577 NC_014364.1 2757267 2758211 D InterPro IPR000620; KEGG: sil:SPO0228 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: membrane protein, ; PFAM: EamA-like transporter family; hypothetical protein 2757267..2758211 Spirochaeta smaragdinae DSM 11293 9490689 YP_003804282.1 CDS Spirs_2578 NC_014364.1 2758439 2759425 R COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395:IPR020471; KEGG: str:Sterm_3216 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: uncharacterized protein; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(2758439..2759425) Spirochaeta smaragdinae DSM 11293 9490690 YP_003804283.1 CDS Spirs_2579 NC_014364.1 2759710 2760720 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: bac:BamMC406_1347 inositol 2-dehydrogenase; PFAM: oxidoreductase domain protein; oxidoreductase domain; PRIAM: inositol 2-dehydrogenase; SPTR: inositol 2-dehydrogenase; PFAM: oxidoreductase family, NAD-binding Rossmann fold; inositol 2-dehydrogenase complement(2759710..2760720) Spirochaeta smaragdinae DSM 11293 9490691 YP_003804284.1 CDS Spirs_2580 NC_014364.1 2760722 2761519 R COGs: COG3622 hydroxypyruvate isomerase; InterPro IPR012307; KEGG: htu:Htur_4472 hydroxypyruvate isomerase; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: hydroxypyruvate isomerase; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase complement(2760722..2761519) Spirochaeta smaragdinae DSM 11293 9490692 YP_003804285.1 CDS Spirs_2581 NC_014364.1 2761804 2762817 D COGs: COG1609 transcriptional regulators; InterPro IPR013838:IPR000843; KEGG: hor:Hore_14510 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 2761804..2762817 Spirochaeta smaragdinae DSM 11293 9490693 YP_003804286.1 CDS Spirs_2582 NC_014364.1 2762819 2763754 D InterPro IPR000620; KEGG: cby:CLM_1318 UAA transporter family; PFAM: protein of unknown function DUF6 transmembrane; SPTR: UAA transporter family; PFAM: EamA-like transporter family; hypothetical protein 2762819..2763754 Spirochaeta smaragdinae DSM 11293 9490694 YP_003804287.1 CDS Spirs_2583 NC_014364.1 2763793 2764932 D InterPro IPR018252:IPR011701; KEGG: dat:HRM2_33570 permease of the major facilitator superfamily; PFAM: major facilitator superfamily MFS_1; SPTR: permease of the major facilitator superfamily; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 2763793..2764932 Spirochaeta smaragdinae DSM 11293 9490695 YP_003804288.1 CDS Spirs_2584 NC_014364.1 2764987 2765835 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594:IPR005467:IPR004358; KEGG: mth:MTH468 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation/phosphoacceptor; SMART: ATP-binding region ATPase domain protein; SPTR: sensory transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 2764987..2765835 Spirochaeta smaragdinae DSM 11293 9490696 YP_003804289.1 CDS Spirs_2585 NC_014364.1 2765917 2767071 R COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE1992 OmpA family protein; PFAM: OmpA/MotB domain protein; SPTR: OmpA family protein; PFAM: OmpA family; OmpA/MotB domain-containing protein complement(2765917..2767071) Spirochaeta smaragdinae DSM 11293 9490697 YP_003804290.1 CDS Spirs_2586 NC_014364.1 2767205 2767945 R InterPro IPR006714; KEGG: tde:TDE1409 flagellar filament outer layer protein FlaA, PFAM: flagellar filament outer layer protein FlaA; SPTR: flagellar filament outer layer protein FlaA, ; PFAM: flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA complement(2767205..2767945) Spirochaeta smaragdinae DSM 11293 9490698 YP_003804291.1 CDS Spirs_2587 NC_014364.1 2767948 2768679 R InterPro IPR006714; KEGG: tde:TDE1408 flagellar filament outer layer protein FlaA, PFAM: flagellar filament outer layer protein FlaA; SPTR: flagellar filament outer layer protein FlaA, ; PFAM: flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA complement(2767948..2768679) Spirochaeta smaragdinae DSM 11293 9490699 YP_003804292.1 CDS Spirs_2588 NC_014364.1 2768887 2769885 D COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: tpp:TPASS_0662 fructose-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: fructose-bisphosphate aldolase; SPTR: fructose-bisphosphate aldolase; TIGRFAM: fructose-1,6-bisphosphate aldolase, class II; ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist; fructose-1,6-bisphosphate aldolase, class II 2768887..2769885 Spirochaeta smaragdinae DSM 11293 9490700 YP_003804293.1 CDS Spirs_2589 NC_014364.1 2770009 2770722 R KEGG: msl:Msil_1524 NnrS family protein; SPTR: uncharacterized protein; hypothetical protein complement(2770009..2770722) Spirochaeta smaragdinae DSM 11293 9490701 YP_003804294.1 CDS Spirs_2590 NC_014364.1 2770887 2771417 D COGs: COG0290 translation initiation factor 3 (IF-3); InterPro IPR019813:IPR019814:IPR019815:IPR001288; KEGG: tde:TDE2156 translation initiation factor IF-3; PFAM: translation initiation factor 3-like; SPTR: translation initiation factor IF-3; TIGRFAM: translation initiation factor IF-3; PFAM: translation initiation factor IF-3, C-terminal domain; translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3; translation initiation factor IF-3 2770887..2771417 Spirochaeta smaragdinae DSM 11293 9490702 YP_003804295.1 CDS Spirs_2591 NC_014364.1 2771441 2771641 D InterPro IPR018265:IPR001706; KEGG: bre:BRE_187 50S ribosomal protein L35; PFAM: ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: ribosomal protein L35; PFAM: ribosomal protein L35; TIGRFAM: ribosomal protein L35; 50S ribosomal protein L35 2771441..2771641 Spirochaeta smaragdinae DSM 11293 9490703 YP_003804296.1 CDS Spirs_2592 NC_014364.1 2771656 2772015 D COGs: COG0292 ribosomal protein L20; InterPro IPR005813; KEGG: sca:Sca_1284 50S ribosomal protein L20; PFAM: ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: ribosomal protein L20; PFAM: ribosomal protein L20; TIGRFAM: ribosomal protein L20; 50S ribosomal protein L20 2771656..2772015 Spirochaeta smaragdinae DSM 11293 9490704 YP_003804297.1 CDS Spirs_2593 NC_014364.1 2772019 2772417 D KEGG: tde:TDE2153 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2772019..2772417 Spirochaeta smaragdinae DSM 11293 9490705 YP_003804298.1 CDS Spirs_2594 NC_014364.1 2772452 2772697 D KEGG: tye:THEYE_A0621 hypothetical protein; SPTR: uncharacterized protein; PFAM: cell division protein ZapA; hypothetical protein 2772452..2772697 Spirochaeta smaragdinae DSM 11293 9490706 YP_003804299.1 CDS Spirs_2595 NC_014364.1 2772908 2773741 D InterPro IPR009875; KEGG: tde:TDE0214 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; PFAM: PilZ domain; type IV pilus assembly PilZ 2772908..2773741 Spirochaeta smaragdinae DSM 11293 9490708 YP_003804300.1 CDS Spirs_2596 NC_014364.1 2773742 2774851 D InterPro IPR001440:IPR013105:IPR019734:IPR013026; KEGG: btu:BT0733A tetratricopeptide repeat family protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SPTR: Tetratricopeptide repeat family protein; hypothetical protein 2773742..2774851 Spirochaeta smaragdinae DSM 11293 9490709 YP_003804301.1 CDS Spirs_2597 NC_014364.1 2775142 2776002 D COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: tpp:TPASS_0792 flagellar filament 33 kDa core protein; PFAM: flagellin domain protein; SPTR: flagellar filament 33 kDa core protein; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein 2775142..2776002 Spirochaeta smaragdinae DSM 11293 9490710 YP_003804302.1 CDS Spirs_2598 NC_014364.1 2776241 2777086 D COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR001029; KEGG: tde:TDE1475 flagellar filament core protein; PFAM: flagellin domain protein; SPTR: flagellar filament 30.7 kDa core protein; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region; flagellin domain-containing protein 2776241..2777086 Spirochaeta smaragdinae DSM 11293 9490711 YP_003804303.1 CDS Spirs_2599 NC_014364.1 2777194 2777571 D InterPro IPR005186; KEGG: tde:TDE1473 flagellin FlaG, PFAM: flagellar protein FlaG protein; SPTR: Flagellin FlaG, ; PFAM: FlaG protein; flagellar protein FlaG protein 2777194..2777571 Spirochaeta smaragdinae DSM 11293 9490712 YP_003804304.1 CDS Spirs_2600 NC_014364.1 2777606 2779543 D COGs: COG1345 flagellar capping protein; InterPro IPR003481:IPR010809; KEGG: tde:TDE1472 flagellar hook-associated protein FliD; PFAM: flagellar hook-associated 2 domain protein; flagellar hook-associated protein 2 domain protein; SPTR: flagellar hook-associated protein 2; PFAM: flagellar hook-associated protein 2 C-terminus; flagellar hook-associated 2 domain-containing protein 2777606..2779543 Spirochaeta smaragdinae DSM 11293 9490713 YP_003804305.1 CDS Spirs_2601 NC_014364.1 2779569 2780480 D KEGG: tde:TDE1471 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2779569..2780480 Spirochaeta smaragdinae DSM 11293 9490714 YP_003804306.1 CDS Spirs_2602 NC_014364.1 2780477 2781595 D InterPro IPR009875; KEGG: tde:TDE1318 hypothetical protein; PFAM: type IV pilus assembly PilZ; SPTR: uncharacterized protein; PFAM: PilZ domain; type IV pilus assembly PilZ 2780477..2781595 Spirochaeta smaragdinae DSM 11293 9490715 YP_003804307.1 CDS Spirs_2603 NC_014364.1 2781641 2781904 D KEGG: tde:TDE1470 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2781641..2781904 Spirochaeta smaragdinae DSM 11293 9490716 YP_003804308.1 CDS Spirs_2604 NC_014364.1 2781917 2782345 D COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: drm:Dred_2888 hypothetical protein; PFAM: protein of unknown function UPF0079; SPTR: uncharacterized protein; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: conserved hypothetical nucleotide-binding protein; hypothetical protein 2781917..2782345 Spirochaeta smaragdinae DSM 11293 9490717 YP_003804309.1 CDS Spirs_2605 NC_014364.1 2782342 2783019 D COGs: COG1214 Inactive homolog of metal-dependent protease molecular chaperone; InterPro IPR000905; KEGG: nth:Nther_0400 peptidase M22 glycoprotease; PFAM: peptidase M22 glycoprotease; SPTR: Universal bacterial protein YeaZ; PFAM: glycoprotease family; peptidase M22 glycoprotease 2782342..2783019 Spirochaeta smaragdinae DSM 11293 9490718 YP_003804310.1 CDS Spirs_2606 NC_014364.1 2782991 2784127 D COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: tde:TDE1467 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; PFAM: HD domain; metal dependent phosphohydrolase 2782991..2784127 Spirochaeta smaragdinae DSM 11293 9490719 YP_003804311.1 CDS Spirs_2607 NC_014364.1 2784134 2784385 R COGs: COG1551 carbon storage regulator (could also regulate swarming and quorum sensing); InterPro IPR003751; KEGG: tpp:TPASS_0657 carbon storage regulator; PFAM: carbon storage regulator; SPTR: carbon storage regulator; TIGRFAM: carbon storage regulator; PFAM: Global regulator protein family; TIGRFAM: carbon storage regulator (csrA); carbon storage regulator CsrA complement(2784134..2784385) Spirochaeta smaragdinae DSM 11293 9490720 YP_003804312.1 CDS Spirs_2608 NC_014364.1 2784379 2784837 R COGs: COG1699 conserved hypothetical protein; InterPro IPR003775; KEGG: tde:TDE2354 flagellar assembly protein FliW; PFAM: protein of unknown function DUF180; SPTR: flagellar assembly factor fliW; PFAM: FliW protein; hypothetical protein complement(2784379..2784837) Spirochaeta smaragdinae DSM 11293 9490721 YP_003804313.1 CDS Spirs_2609 NC_014364.1 2784869 2786113 R COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001492:IPR010810:IPR013384; KEGG: tpp:TPASS_0659 flagellar hook-associated protein FlgL; PFAM: flagellin domain protein; flagellin hook IN repeat protein; SPTR: flagellar hook-associated protein 3; TIGRFAM: flagellar hook-associated protein 3; PFAM: Bacterial flagellin N-terminal helical region; Flagellin hook IN motif; Bacterial flagellin C-terminal helical region; TIGRFAM: flagellar hook-associated protein 3; flagellar hook-associated protein 3 complement(2784869..2786113) Spirochaeta smaragdinae DSM 11293 9490722 YP_003804314.1 CDS Spirs_2610 NC_014364.1 2786125 2788008 R COGs: COG1256 flagellar hook-associated protein; InterPro IPR010810:IPR010930:IPR002371; KEGG: tde:TDE2352 flagellar hook-associated protein FlgK; PFAM: protein of unknown function DUF1078 domain protein; flagellin hook IN repeat protein; SPTR: flagellar hook-associated protein FlgK; TIGRFAM: flagellar hook-associated protein FlgK; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK; flagellar hook-associated protein FlgK complement(2786125..2788008) Spirochaeta smaragdinae DSM 11293 9490723 YP_003804315.1 CDS Spirs_2611 NC_014364.1 2788018 2788512 R KEGG: tde:TDE2351 hypothetical protein; SPTR: uncharacterized protein; PFAM: FlgN protein; hypothetical protein complement(2788018..2788512) Spirochaeta smaragdinae DSM 11293 9490724 YP_003804316.1 CDS Spirs_2612 NC_014364.1 2788696 2789631 D COGs: COG0492 thioredoxin reductase; InterPro IPR008255:IPR013027:IPR005982:IPR000103; KEGG: tpp:TPASS_0814 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase; thioredoxin reductase 2788696..2789631 Spirochaeta smaragdinae DSM 11293 9490725 YP_003804317.1 CDS Spirs_2613 NC_014364.1 2789638 2791314 D COGs: COG1472 beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: tde:TDE0024 glycosy hydrolase family protein; PFAM: glycoside hydrolase; PRIAM: beta-N-acetylhexosaminidase; SPTR: glycosyl hydrolase, family 3; PFAM: glycosyl hydrolase family 3 N terminal domain; beta-N-acetylhexosaminidase 2789638..2791314 Spirochaeta smaragdinae DSM 11293 9490726 YP_003804318.1 CDS Spirs_2614 NC_014364.1 2791311 2792210 D COGs: COG3393 acetyltransferase; InterPro IPR000182; KEGG: tpp:TPASS_0815 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase, gnat family; PFAM: FR47-like protein; GCN5-like N-acetyltransferase 2791311..2792210 Spirochaeta smaragdinae DSM 11293 9490727 YP_003804319.1 CDS Spirs_2615 NC_014364.1 2792244 2793362 R KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein complement(2792244..2793362) Spirochaeta smaragdinae DSM 11293 9490728 YP_003804320.1 CDS Spirs_2616 NC_014364.1 2793499 2794956 D COGs: COG0297 glycogen synthase; InterPro IPR013534:IPR001296:IPR011835; KEGG: tde:TDE1582 glycogen synthase; PFAM: Starch synthase catalytic domain protein; glycosyl transferase group 1; PRIAM: Starch synthase; SPTR: glycogen synthase; TIGRFAM: glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase catalytic domain; glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type; ADP-glucose type glycogen/starch synthase 2793499..2794956 Spirochaeta smaragdinae DSM 11293 9490729 YP_003804321.1 CDS Spirs_2617 NC_014364.1 2794923 2796101 R COGs: COG3359 exonuclease; KEGG: sth:STH1622 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2794923..2796101) Spirochaeta smaragdinae DSM 11293 9490730 YP_003804322.1 CDS Spirs_2618 NC_014364.1 2796098 2798401 R COGs: COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster; InterProIPR011545:IPR001650:IPR018973:IPR014001:IPR 014021; KEGG: bbe:BBR47_50510 helicase; PFAM: DEAD/DEAH box helicase domain protein; helicase; protein of unknown function DUF1998; SMART: DEAD-like helicase ; helicase; SPTR: helicase; PFAM: Helicase conserved C-terminal domain; Domain of unknown function (DUF1998); DEAD/DEAH box helicase; DEAD/DEAH box helicase complement(2796098..2798401) Spirochaeta smaragdinae DSM 11293 9490731 YP_003804323.1 CDS Spirs_2619 NC_014364.1 2798510 2799793 D COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005836:IPR005835; KEGG: tde:TDE2035 glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; SPTR: glucose-1-phosphate adenylyltransferase; PFAM: nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase; nucleotidyl transferase 2798510..2799793 Spirochaeta smaragdinae DSM 11293 9490732 YP_003804324.1 CDS Spirs_2620 NC_014364.1 2799786 2800181 R InterPro IPR000086; KEGG: aco:Amico_1257 NUDIX hydrolase; PFAM: NUDIX hydrolase; SPTR: CTP pyrophosphohydrolase; PFAM: NUDIX domain; NUDIX hydrolase complement(2799786..2800181) Spirochaeta smaragdinae DSM 11293 9490733 YP_003804325.1 CDS Spirs_2621 NC_014364.1 2800203 2800616 R KEGG: btu:BT0157 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2800203..2800616) Spirochaeta smaragdinae DSM 11293 9490734 YP_003804326.1 CDS Spirs_2622 NC_014364.1 2800702 2801244 R KEGG: smf:Smon_1023 oligoendopeptidase, M3 family; SPTR: oligoendopeptidase, M3 family; hypothetical protein complement(2800702..2801244) Spirochaeta smaragdinae DSM 11293 9490735 YP_003804327.1 CDS Spirs_2623 NC_014364.1 2801241 2802782 R COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: gtn:GTNG_1348 hypothetical protein; PFAM: YjeF-family domain protein; protein of unknown function UPF0031; SPTR: uncharacterized protein; TIGRFAM: carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein N-terminus; carbohydrate kinase; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related; carbohydrate kinase complement(2801241..2802782) Spirochaeta smaragdinae DSM 11293 9490736 YP_003804328.1 CDS Spirs_2624 NC_014364.1 2802782 2803939 R InterPro IPR019775; KEGG: tde:TDE0857 lipoprotein; SPTR: lipoprotein; hypothetical protein complement(2802782..2803939) Spirochaeta smaragdinae DSM 11293 9490737 YP_003804329.1 CDS Spirs_2625 NC_014364.1 2804140 2806881 D COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); InterProIPR000185:IPR011115:IPR011130:IPR011116:IPR 004027:IPR014018; KEGG: tde:TDE1898 preprotein translocase subunit SecA; PFAM: SecA DEAD domain protein; SecA preprotein cross-linking region; SecA Wing and Scaffold; SEC-C motif domain protein; SPTR: protein translocase subunit secA; TIGRFAM: preprotein translocase, Secsubunit alpha; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, Secsubunit alpha; preprotein translocasesubunit SecA 2804140..2806881 Spirochaeta smaragdinae DSM 11293 9490738 YP_003804330.1 CDS Spirs_2626 NC_014364.1 2807001 2808113 R COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR018392:IPR016047:IPR002482; KEGG: tde:TDE2753 LysM/M23/M37 peptidase; PFAM: peptidase M23; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: LysM domain/M23/M37 peptidase domain protein; PFAM: peptidase family M23; LysM domain; peptidase M23 complement(2807001..2808113) Spirochaeta smaragdinae DSM 11293 9490739 YP_003804331.1 CDS Spirs_2627 NC_014364.1 2808184 2808606 D InterPro IPR019759:IPR000223; KEGG: tai:Taci_1355 signal peptidase I; PFAM: peptidase S24/S26A/S26B, conserved region; SPTR: Signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type; signal peptidase I 2808184..2808606 Spirochaeta smaragdinae DSM 11293 9490740 YP_003804332.1 CDS Spirs_2628 NC_014364.1 2808599 2810488 D COGs: COG0768 cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311:IPR001460:IPR005543; KEGG: tde:TDE1314 penicillin-binding protein; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; PRIAM: peptidoglycan glycosyltransferase; SMART: PASTA domain containing protein; SPTR: Penicillin-binding protein; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding protein dimerisation domain; PASTA domain; peptidoglycan glycosyltransferase 2808599..2810488 Spirochaeta smaragdinae DSM 11293 9490741 YP_003804333.1 CDS Spirs_2629 NC_014364.1 2810503 2812302 D COGs: COG2604 conserved hypothetical protein; InterPro IPR002826; KEGG: tde:TDE1315 hypothetical protein; PFAM: protein of unknown function DUF115; SPTR: Conserved domain protein; PFAM: protein of unknown function DUF115; hypothetical protein 2810503..2812302 Spirochaeta smaragdinae DSM 11293 9490742 YP_003804334.1 CDS Spirs_2630 NC_014364.1 2812591 2813199 D KEGG: gvi:glr2661 hypothetical protein; SPTR: Glr2661 protein; hypothetical protein 2812591..2813199 Spirochaeta smaragdinae DSM 11293 9490743 YP_003804335.1 CDS Spirs_2632 NC_014364.1 2814413 2814892 R KEGG: hoh:Hoch_5174 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2814413..2814892) Spirochaeta smaragdinae DSM 11293 9490745 YP_003804336.1 CDS Spirs_2633 NC_014364.1 2815066 2817555 D COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR001455:IPR013027:IPR004099:IPR001763; KEGG: pdi:BDI_0541 pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; rhodanese; SirA family protein; SMART: rhodanese; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; SirA-like protein; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 2815066..2817555 Spirochaeta smaragdinae DSM 11293 9490746 YP_003804337.1 CDS Spirs_2634 NC_014364.1 2817785 2818027 D KEGG: hor:Hore_00320 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2817785..2818027 Spirochaeta smaragdinae DSM 11293 9490747 YP_003804338.1 CDS Spirs_2635 NC_014364.1 2818024 2818419 D COGs: COG4113 nucleic acid-binding protein contains PIN domain; InterPro IPR002716; KEGG: cpb:Cphamn1_1961 twitching motility protein PilT; PFAM: twitching motility protein PilT; SPTR: twitching motility protein PilT; PFAM: PIN domain; twitching motility protein PilT 2818024..2818419 Spirochaeta smaragdinae DSM 11293 9490748 YP_003804339.1 CDS Spirs_2636 NC_014364.1 2818488 2820035 D InterPro IPR016129; KEGG: tde:TDE1705 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2818488..2820035 Spirochaeta smaragdinae DSM 11293 9490749 YP_003804340.1 CDS Spirs_2637 NC_014364.1 2820293 2820517 R SPTR: uncharacterized protein; hypothetical protein complement(2820293..2820517) Spirochaeta smaragdinae DSM 11293 9490750 YP_003804341.1 CDS Spirs_2638 NC_014364.1 2820594 2822075 R COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR016160:IPR015590; KEGG: ele:Elen_1838 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase (NAD+); PFAM: aldehyde dehydrogenase family; aldehyde dehydrogenase complement(2820594..2822075) Spirochaeta smaragdinae DSM 11293 9490751 YP_003804342.1 CDS Spirs_2639 NC_014364.1 2822273 2824357 D COGs: COG3284 transcriptional activator of acetoin/glycerol metabolism; InterProIPR002078:IPR003018:IPR013767:IPR002197:IPR 000014:IPR003593:IPR020441; KEGG: swo:Swol_1699 acetoin operon expression regulatory protein; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; PAS fold domain protein; helix-turn-helix Fis-type; SMART: ATPase AAA; PAS domain containing protein; SPTR: acetoin operon expression regulatory protein; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; PAS fold; TIGRFAM: PAS domain S-box; Fis family transcriptional regulator 2822273..2824357 Spirochaeta smaragdinae DSM 11293 9490752 YP_003804343.1 CDS Spirs_2640 NC_014364.1 2824427 2825464 D InterPro IPR004843; KEGG: cac:CAC2806 Icc family phosphohydrolase; PFAM: metallophosphoesterase; SPTR: Predicted phosphohydrolase, Icc family; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase 2824427..2825464 Spirochaeta smaragdinae DSM 11293 9490753 YP_003804344.1 CDS Spirs_2641 NC_014364.1 2825448 2826044 R InterPro IPR001647; KEGG: cac:CAC2773 AcrR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulators, AcrR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(2825448..2826044) Spirochaeta smaragdinae DSM 11293 9490754 YP_003804345.1 CDS Spirs_2642 NC_014364.1 2826078 2826989 R COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: cce:Ccel_0630 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator complement(2826078..2826989) Spirochaeta smaragdinae DSM 11293 9490755 YP_003804346.1 CDS Spirs_2643 NC_014364.1 2826998 2828824 R COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR004010; KEGG: drt:Dret_2092 pyruvate carboxyltransferase; PFAM: pyruvate carboxyltransferase; Cache domain protein; SPTR: pyruvate carboxyltransferase; PFAM: Cache domain; HMGL-like; pyruvate carboxyltransferase complement(2826998..2828824) Spirochaeta smaragdinae DSM 11293 9490756 YP_003804347.1 CDS Spirs_2644 NC_014364.1 2829057 2829980 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: cpy:Cphy_3277 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; sugar ABC transporter periplasmic protein complement(2829057..2829980) Spirochaeta smaragdinae DSM 11293 9490757 YP_003804348.1 CDS Spirs_2645 NC_014364.1 2830041 2831072 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR000897:IPR001851; KEGG: cpy:Cphy_3278 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2830041..2831072) Spirochaeta smaragdinae DSM 11293 9490758 YP_003804349.1 CDS Spirs_2646 NC_014364.1 2831124 2832647 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593:IPR015861; KEGG: cpy:Cphy_3279 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter complement(2831124..2832647) Spirochaeta smaragdinae DSM 11293 9490759 YP_003804350.1 CDS Spirs_2647 NC_014364.1 2832709 2834175 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439; KEGG: cpy:Cphy_3280 ABC-type sugar transport system ATPase component-like protein; PRIAM: sugar ATP transporter ATPase; SPTR: uncharacterized protein; sugar ATP transporter ATPase complement(2832709..2834175) Spirochaeta smaragdinae DSM 11293 9490760 YP_003804351.1 CDS Spirs_2648 NC_014364.1 2834172 2835194 R COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR010559:IPR003594; KEGG: cpy:Cphy_3281 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(2834172..2835194) Spirochaeta smaragdinae DSM 11293 9490761 YP_003804352.1 CDS Spirs_2649 NC_014364.1 2835203 2836816 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR018062:IPR001789:IPR000005:IPR018060:IPR 020449; KEGG: cpy:Cphy_3282 AraC family transcriptional regulator; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(2835203..2836816) Spirochaeta smaragdinae DSM 11293 9490762 YP_003804353.1 CDS Spirs_2650 NC_014364.1 2836954 2838879 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089; KEGG: gsu:GSU1304 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; Cache domain protein; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 2836954..2838879 Spirochaeta smaragdinae DSM 11293 9490763 YP_003804354.1 CDS Spirs_2651 NC_014364.1 2839027 2840658 R InterPro IPR019758; KEGG: tva:TVAG_025170 fimbriae-associated protein; SPTR: Fimbriae-associated protein; hypothetical protein complement(2839027..2840658) Spirochaeta smaragdinae DSM 11293 9490764 YP_003804355.1 CDS Spirs_2654 NC_014364.1 2842026 2842223 R hypothetical protein complement(2842026..2842223) Spirochaeta smaragdinae DSM 11293 9490767 YP_003804356.1 CDS Spirs_2655 NC_014364.1 2842350 2843861 R COGs: COG3534 alpha-L-arabinofuranosidase; InterPro IPR010720; KEGG: bha:BH1861 alpha-L-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase domain protein; PRIAM: alpha-N-arabinofuranosidase; SMART: alpha-L-arabinofuranosidase domain protein; SPTR: alpha-N-arabinofuranosidase; PFAM: alpha-L-arabinofuranosidase C-terminus; alpha-N-arabinofuranosidase complement(2842350..2843861) Spirochaeta smaragdinae DSM 11293 9490768 YP_003804357.1 CDS Spirs_2656 NC_014364.1 2843904 2844755 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: bld:BLi03022 AraQ; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: AraQ; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2843904..2844755) Spirochaeta smaragdinae DSM 11293 9490769 YP_003804358.1 CDS Spirs_2657 NC_014364.1 2844756 2845643 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: gtn:GTNG_1793 L-arabinose transport system (permease); PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporter inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(2844756..2845643) Spirochaeta smaragdinae DSM 11293 9490770 YP_003804359.1 CDS Spirs_2658 NC_014364.1 2845732 2847048 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gtn:GTNG_1794 L-arabinose transporter (sugar-binding protein); PFAM: extracellular solute-binding protein family 1; SPTR: L-arabinose transporter (Sugar-binding protein); PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2845732..2847048) Spirochaeta smaragdinae DSM 11293 9490771 YP_003804360.1 CDS Spirs_2659 NC_014364.1 2847295 2848221 D COGs: COG4189 transcriptional regulator protein; InterPro IPR001845:IPR016943; KEGG: smd:Smed_5584 transcriptional regulator, TrmB; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: transcriptional regulator, TrmB; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 2847295..2848221 Spirochaeta smaragdinae DSM 11293 9490772 YP_003804361.1 CDS Spirs_2660 NC_014364.1 2848254 2849732 R COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dat:HRM2_09060 methyltransferase (radical SAM domain); PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: methyltransferase (radical SAM domain); PFAM: radical SAM superfamily; B12 binding domain; radical SAM protein complement(2848254..2849732) Spirochaeta smaragdinae DSM 11293 9490773 YP_003804362.1 CDS Spirs_2661 NC_014364.1 2849738 2851399 R COGs: COG1227 inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR004097; KEGG: dap:Dacet_2031 inorganic diphosphatase; PFAM: DHHA2 domain protein; CBS domain containing protein; PRIAM: inorganic diphosphatase; SPTR: inorganic diphosphatase; PFAM: DHH family; DHHA2 domain; CBS domain; inorganic diphosphatase complement(2849738..2851399) Spirochaeta smaragdinae DSM 11293 9490774 YP_003804363.1 CDS Spirs_2662 NC_014364.1 2851526 2851972 D COGs: COG0698 ribose 5-phosphate isomerase RpiB; InterPro IPR003500:IPR004785; KEGG: cno:NT01CX_0543 ribose-5-phosphate isomerase B; PFAM: ribose/galactose isomerase; SPTR: ribose 5-phosphate isomerase B; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase B; PFAM: ribose/Galactose Isomerase; TIGRFAM: ribose 5-phosphate isomerase B; sugar-phosphate isomerases, RpiB/LacA/LacB family; RpiB/LacA/LacB family sugar-phosphate isomerase 2851526..2851972 Spirochaeta smaragdinae DSM 11293 9490775 YP_003804364.1 CDS Spirs_2663 NC_014364.1 2851983 2853254 D COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594:IPR005467:IPR004358; KEGG: dba:Dbac_2294 histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase dimerisation and phosphoacceptor region; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase 2851983..2853254 Spirochaeta smaragdinae DSM 11293 9490776 YP_003804365.1 CDS Spirs_2664 NC_014364.1 2853254 2854285 D InterPro IPR011611; KEGG: bth:BT_2799 PfkB family carbohydrate kinase; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 2853254..2854285 Spirochaeta smaragdinae DSM 11293 9490777 YP_003804366.1 CDS Spirs_2665 NC_014364.1 2854237 2855829 R KEGG: tde:TDE0126 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2854237..2855829) Spirochaeta smaragdinae DSM 11293 9490778 YP_003804367.1 CDS Spirs_2666 NC_014364.1 2855840 2856238 R COGs: COG0295 Cytidine deaminase; InterPro IPR016192:IPR002125:IPR006262; KEGG: aac:Aaci_0737 pyrimidine-nucleoside phosphorylase; PFAM: CMP/dCMP deaminase zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: cytidine deaminase; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric; cytidine deaminase complement(2855840..2856238) Spirochaeta smaragdinae DSM 11293 9490779 YP_003804368.1 CDS Spirs_2667 NC_014364.1 2856304 2857497 R COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR001261:IPR002933:IPR011650; KEGG: mta:Moth_0710 peptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: peptidase M20; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: selenium metabolism hydrolase; peptidase M20 complement(2856304..2857497) Spirochaeta smaragdinae DSM 11293 9490780 YP_003804369.1 CDS Spirs_2668 NC_014364.1 2857576 2858508 R COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: npu:Npun_R4718 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2857576..2858508) Spirochaeta smaragdinae DSM 11293 9490781 YP_003804370.1 CDS Spirs_2669 NC_014364.1 2858501 2859571 R COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: tit:Thit_0432 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Sugar ABC transporter permease; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2858501..2859571) Spirochaeta smaragdinae DSM 11293 9490782 YP_003804371.1 CDS Spirs_2670 NC_014364.1 2859568 2861112 R COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR017871:IPR003439:IPR003593; KEGG: ate:Athe_1781 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(2859568..2861112) Spirochaeta smaragdinae DSM 11293 9490783 YP_003804372.1 CDS Spirs_2671 NC_014364.1 2861220 2862227 R COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: gau:GAU_0026 lipoprotein; PFAM: basic membrane lipoprotein; SPTR: uncharacterized protein; PFAM: Basic membrane protein; basic membrane lipoprotein complement(2861220..2862227) Spirochaeta smaragdinae DSM 11293 9490784 YP_003804373.1 CDS Spirs_2672 NC_014364.1 2862479 2863726 R COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dau:Daud_2034 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(2862479..2863726) Spirochaeta smaragdinae DSM 11293 9490785 YP_003804374.1 CDS Spirs_2673 NC_014364.1 2863686 2865092 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR013838:IPR006680; KEGG: cdl:CDR20291_1989 amidohydrolase; PFAM: amidohydrolase; SPTR: uncharacterized protein; PFAM: Amidohydrolase family; amidohydrolase complement(2863686..2865092) Spirochaeta smaragdinae DSM 11293 9490786 YP_003804375.1 CDS Spirs_2674 NC_014364.1 2865116 2866135 R KEGG: hor:Hore_19200 pyrimidine reductase, riboflavin biosynthesis; SPTR: uncharacterized protein; pyrimidine reductase, riboflavin biosynthesis complement(2865116..2866135) Spirochaeta smaragdinae DSM 11293 9490787 YP_003804376.1 CDS Spirs_2675 NC_014364.1 2866183 2867223 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cpo:COPRO5265_1470 catabolite control protein A (glucose-resistance amylase regulator); PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Catabolite control protein A (glucose-resistance amylase regulator); PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(2866183..2867223) Spirochaeta smaragdinae DSM 11293 9490788 YP_003804377.1 CDS Spirs_2676 NC_014364.1 2867321 2867668 R InterPro IPR013096; KEGG: hmo:HM1_2283 hypothetical protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain; cupin complement(2867321..2867668) Spirochaeta smaragdinae DSM 11293 9490789 YP_003804378.1 CDS Spirs_2677 NC_014364.1 2867709 2868236 R InterPro IPR006683:IPR003736; KEGG: sdl:Sdel_1536 thioesterase superfamily protein; PFAM: thioesterase superfamily protein; SPTR: uncharacterized protein; manually curated; PFAM: thioesterase superfamily; TIGRFAM: uncharacterized domain 1; thioesterase superfamily protein complement(2867709..2868236) Spirochaeta smaragdinae DSM 11293 9490790 YP_003804379.1 CDS Spirs_2678 NC_014364.1 2868274 2868792 D COGs: COG0663 carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: pmo:Pmob_0648 ferripyochelin binding protein (fbp); SPTR: Ferripyochelin binding protein (Fbp); PFAM: Bacterial transferase hexapeptide (three repeats); ferripyochelin binding protein (fbp) 2868274..2868792 Spirochaeta smaragdinae DSM 11293 9490791 YP_003804380.1 CDS Spirs_2679 NC_014364.1 2868841 2869716 R KEGG: har:HEAR1065 hypothetical protein; SPTR: receptor; hypothetical protein complement(2868841..2869716) Spirochaeta smaragdinae DSM 11293 9490792 YP_003804381.1 CDS Spirs_2680 NC_014364.1 2869814 2870590 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: kcr:Kcr_0822 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(2869814..2870590) Spirochaeta smaragdinae DSM 11293 9490793 YP_003804382.1 CDS Spirs_2681 NC_014364.1 2870733 2871695 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: cdl:CDR20291_0305 ribose ABC transporter permease; PFAM: inner-membrane translocator; SPTR: ribose ABC transporter permease protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2870733..2871695) Spirochaeta smaragdinae DSM 11293 9490794 YP_003804383.1 CDS Spirs_2682 NC_014364.1 2871723 2873228 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593; KEGG: gym:GYMC10_3889 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter complement(2871723..2873228) Spirochaeta smaragdinae DSM 11293 9490795 YP_003804384.1 CDS Spirs_2683 NC_014364.1 2873341 2874387 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: cvi:CV_3016 ribose ABC transporter substrate binding protein; SPTR: uncharacterized protein; PFAM: family; sugar ABC transporter periplasmic protein complement(2873341..2874387) Spirochaeta smaragdinae DSM 11293 9490796 YP_003804385.1 CDS Spirs_2684 NC_014364.1 2874445 2875500 R COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: cce:Ccel_1007 alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: uncharacterized protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(2874445..2875500) Spirochaeta smaragdinae DSM 11293 9490797 YP_003804386.1 CDS Spirs_2685 NC_014364.1 2875514 2876335 R KEGG: rxy:Rxyl_2378 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(2875514..2876335) Spirochaeta smaragdinae DSM 11293 9490798 YP_003804387.1 CDS Spirs_2686 NC_014364.1 2876384 2877424 R COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: bth:BT_4424 sorbitol dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: uncharacterized protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(2876384..2877424) Spirochaeta smaragdinae DSM 11293 9490799 YP_003804388.1 CDS Spirs_2687 NC_014364.1 2877499 2878347 R COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: hor:Hore_18020 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: 5-dehydro-2-deoxyphosphogluconate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase complement(2877499..2878347) Spirochaeta smaragdinae DSM 11293 9490800 YP_003804389.1 CDS Spirs_2688 NC_014364.1 2878340 2879290 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: tva:TVAG_062910 kinase, pfkB family protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(2878340..2879290) Spirochaeta smaragdinae DSM 11293 9490801 YP_003804390.1 CDS Spirs_2689 NC_014364.1 2879602 2880372 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR018356:IPR001034:IPR014036; KEGG: dfe:Dfer_1716 DeoR family transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: DeoR family transcriptional regulator; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 2879602..2880372 Spirochaeta smaragdinae DSM 11293 9490802 YP_003804391.1 CDS Spirs_2690 NC_014364.1 2880412 2880693 R KEGG: dsy:DSY3875 hypothetical protein; SPTR: membrane protein; hypothetical protein complement(2880412..2880693) Spirochaeta smaragdinae DSM 11293 9490803 YP_003804392.1 CDS Spirs_2691 NC_014364.1 2880683 2881078 R COGs: COG3603 conserved hypothetical protein; InterPro IPR016540; KEGG: mta:Moth_1001 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2880683..2881078) Spirochaeta smaragdinae DSM 11293 9490804 YP_003804393.1 CDS Spirs_2692 NC_014364.1 2881211 2881510 R KEGG: bta:615436 actin filament associated protein 1-like 2; SPTR: uncharacterized protein; hypothetical protein complement(2881211..2881510) Spirochaeta smaragdinae DSM 11293 9490805 YP_003804394.1 CDS Spirs_2693 NC_014364.1 2881512 2881994 R InterPro IPR000782; KEGG: mdo:100012659 similar to transforming growth factor-beta-induced protein ig-h3 precursor (beta ig-h3) (Kerato-epithelin) (RGD-containing collagen-associated protein) (RGD-CAP); PFAM: beta-Ig-H3/fasciclin; SMART: beta-Ig-H3/fasciclin; SPTR: Novel protein similar to vertebrate stabilin 2 (STAB2); PFAM: Fasciclin domain; beta-Ig-H3/fasciclin complement(2881512..2881994) Spirochaeta smaragdinae DSM 11293 9490806 YP_003804395.1 CDS Spirs_2694 NC_014364.1 2882280 2883161 D InterPro IPR006530; KEGG: cpi:Cpin_7148 hypothetical protein; PFAM: hypothetical protein; SPTR: hypothetical protein; hypothetical protein 2882280..2883161 Spirochaeta smaragdinae DSM 11293 9490807 YP_003804396.1 CDS Spirs_2695 NC_014364.1 2883172 2883873 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: apv:Apar_1349 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; SPTR: transcriptional regulatory protein ResD; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 2883172..2883873 Spirochaeta smaragdinae DSM 11293 9490808 YP_003804397.1 CDS Spirs_2696 NC_014364.1 2883870 2885225 D COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003661:IPR003594:IPR005467:IPR004358; KEGG: ctc:CTC00873 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; histidine kinase 2883870..2885225 Spirochaeta smaragdinae DSM 11293 9490809 YP_003804398.1 CDS Spirs_2697 NC_014364.1 2885327 2886742 D KEGG: ncr:NCU07868 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2885327..2886742 Spirochaeta smaragdinae DSM 11293 9490810 YP_003804399.1 CDS Spirs_2698 NC_014364.1 2886763 2889285 R COGs: COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component); InterProIPR001020:IPR000121:IPR004701:IPR005698:IPR 008731:IPR008279:IPR012844:IPR006318:IPR000032; KEGG: rca:Rcas_2048 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PTS system fructose subfamily IIA component; phosphoryl transfer system HPr; PEP-utilising protein mobile region; SPTR: phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; dihydroxyacetone kinase, phosphotransfer subunit; phosphocarrier, HPr family; PFAM: PTS system fructose IIA component; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PTS HPr component phosphorylation site; PEP-utilising enzyme, N-terminal; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; phosphoenolpyruvate-protein phosphotransferase; phosphotransferase System HPr (HPr) Family; phosphoenolpyruvate-protein phosphotransferase complement(2886763..2889285) Spirochaeta smaragdinae DSM 11293 9490811 YP_003804400.1 CDS Spirs_2699 NC_014364.1 2889300 2889926 R COGs: COG2376 dihydroxyacetone kinase; InterPro IPR004007:IPR012737; KEGG: sti:Sthe_3122 dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; SPTR: dihydroxyacetone kinase, L subunit; TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; dihydroxyacetone kinase, L subunit complement(2889300..2889926) Spirochaeta smaragdinae DSM 11293 9490812 YP_003804401.1 CDS Spirs_2700 NC_014364.1 2889964 2890965 R COGs: COG2376 dihydroxyacetone kinase; InterPro IPR004006:IPR012736; KEGG: rca:Rcas_2044 dihydroxyacetone kinase, DhaK subunit; PFAM: Dak kinase; PRIAM: glycerone kinase; SPTR: dihydroxyacetone kinase, DhaK subunit; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; PFAM: Dak1 domain; TIGRFAM: dihydroxyacetone kinase, DhaK subunit; dihydroxyacetone kinase, DhaK subunit complement(2889964..2890965) Spirochaeta smaragdinae DSM 11293 9490813 YP_003804402.1 CDS Spirs_2701 NC_014364.1 2891144 2892268 D COGs: COG0225 peptide methionine sulfoxide reductase; InterPro IPR018039:IPR002569:IPR002579; KEGG: dat:HRM2_08740 MsrAB; PFAM: methionine sulfoxide reductase B; methionine sulfoxide reductase A; PRIAM: peptide-methionine (S)-S-oxide reductase., peptide-methionine (R)-S-oxide reductase; SPTR: MsrAB; TIGRFAM: methionine-R-sulfoxide reductase; peptide methionine sulfoxide reductase; PFAM: SelR domain; peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase; methionine-R-sulfoxide reductase 2891144..2892268 Spirochaeta smaragdinae DSM 11293 9490814 YP_003804403.1 CDS Spirs_2702 NC_014364.1 2892259 2893566 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cac:CAC1456 sugar-binding periplasmic protein; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(2892259..2893566) Spirochaeta smaragdinae DSM 11293 9490815 YP_003804404.1 CDS Spirs_2703 NC_014364.1 2893556 2894227 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: ssa:SSA_0217 two-component response transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(2893556..2894227) Spirochaeta smaragdinae DSM 11293 9490816 YP_003804405.1 CDS Spirs_2704 NC_014364.1 2894220 2895524 R COGs: COG4585 Signal transduction histidine kinase; InterPro IPR011712:IPR003594; KEGG: cac:CAC1454 membrane associated histidine kinase-like ATPase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SPTR: membrane associated histidine kinase-like ATPase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(2894220..2895524) Spirochaeta smaragdinae DSM 11293 9490817 YP_003804406.1 CDS Spirs_2705 NC_014364.1 2895716 2896651 D COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: cac:CAC1453 ribose ABC transporter periplasmic ribose-binding protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; sugar ABC transporter periplasmic protein 2895716..2896651 Spirochaeta smaragdinae DSM 11293 9490818 YP_003804407.1 CDS Spirs_2706 NC_014364.1 2896731 2898236 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR017871:IPR003439:IPR003593:IPR015861; KEGG: tte:TTE0763 ABC-type sugar (aldose) transporter, ATPase component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter protein; PFAM: ABC transporter; sugar ABC transporter ATPase 2896731..2898236 Spirochaeta smaragdinae DSM 11293 9490819 YP_003804408.1 CDS Spirs_2707 NC_014364.1 2898248 2899249 D COGs: COG4158 ABC-type sugar transporter permease component; InterPro IPR001851; KEGG: tte:TTE0205 ribose/xylose/arabinose/galactoside ABC-type transporter permease; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 2898248..2899249 Spirochaeta smaragdinae DSM 11293 9490820 YP_003804409.1 CDS Spirs_2708 NC_014364.1 2899450 2900577 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: rlg:Rleg_1657 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: iron(III) dicitrate-binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 2899450..2900577 Spirochaeta smaragdinae DSM 11293 9490821 YP_003804410.1 CDS Spirs_2709 NC_014364.1 2900591 2901616 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: ara:Arad_8725 hemin transport system; PFAM: transporter permease; SPTR: transporter permease; PFAM: FecCD transport family; transporter permease 2900591..2901616 Spirochaeta smaragdinae DSM 11293 9490822 YP_003804411.1 CDS Spirs_2710 NC_014364.1 2901609 2902349 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR017871:IPR003439:IPR003593; KEGG: vsa:VSAL_p320_29 iron ion ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: transposase; PFAM: ABC transporter; ABC transporter 2901609..2902349 Spirochaeta smaragdinae DSM 11293 9490823 YP_003804412.1 CDS Spirs_2711 NC_014364.1 2902378 2903631 D InterPro IPR018253; KEGG: sti:Sthe_2557 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2902378..2903631 Spirochaeta smaragdinae DSM 11293 9490824 YP_003804413.1 CDS Spirs_2712 NC_014364.1 2903628 2904323 D KEGG: efe:EFER_1097 conserved hypothetical protein; inner membrane protein; SPTR: uncharacterized protein yccS; hypothetical protein 2903628..2904323 Spirochaeta smaragdinae DSM 11293 9490825 YP_003804414.1 CDS Spirs_2713 NC_014364.1 2904443 2905495 R COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterProIPR001497:IPR004026:IPR014048:IPR018060:IPR 016221; KEGG: mmw:Mmwyl1_0128 methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; Ada metal-binding domain protein; SMART: Helix-turn-helix, AraC domain; SPTR: methylated-DNA-[protein]-cysteine S-methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; metal binding domain of Ada; 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; methylated-DNA/protein- cysteinemethyltransferase complement(2904443..2905495) Spirochaeta smaragdinae DSM 11293 9490826 YP_003804415.1 CDS Spirs_2714 NC_014364.1 2905721 2906155 D InterPro IPR001226:IPR008254; KEGG: mpd:MCP_1384 hypothetical protein; PFAM: flavodoxin/nitric oxide synthase; SPTR: Flavodoxin; PFAM: Flavodoxin; flavodoxin/nitric oxide synthase 2905721..2906155 Spirochaeta smaragdinae DSM 11293 9490827 YP_003804416.1 CDS Spirs_2715 NC_014364.1 2906465 2907304 D COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR000150:IPR013200:IPR006379; KEGG: ctc:CTC00366 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase type 3; SPTR: Predicted hydrolase; TIGRFAM: Cof-like hydrolase; HAD-superfamily hydrolase, subfamily IIB; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB; Cof-like hydrolase 2906465..2907304 Spirochaeta smaragdinae DSM 11293 9490828 YP_003804417.1 CDS Spirs_2717 NC_014364.1 2907783 2909084 R COGs: COG3681 conserved hypothetical protein; InterPro IPR010469; KEGG: dde:Dde_0807 hypothetical protein; PFAM: protein of unknown function DUF1063; SPTR: UPF0597 protein Dde_0807; PFAM: serine dehydratase alpha chain; hypothetical protein complement(2907783..2909084) Spirochaeta smaragdinae DSM 11293 9490830 YP_003804418.1 CDS Spirs_2718 NC_014364.1 2909093 2909467 R COGs: COG0251 translation initiation inhibitor yjgF family; InterPro IPR019897:IPR006175:IPR006056; KEGG: tde:TDE2069 endoribonuclease L-PSP, PFAM: endoribonuclease L-PSP; SPTR: uncharacterized protein; TIGRFAM: endoribonuclease L-PSP; PFAM: endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP; endoribonuclease L-PSP complement(2909093..2909467) Spirochaeta smaragdinae DSM 11293 9490831 YP_003804419.1 CDS Spirs_2719 NC_014364.1 2909493 2910035 R COGs: COG0703 shikimate kinase; InterPro IPR000623; KEGG: swo:Swol_0528 shikimate kinase; PFAM: shikimate kinase; PRIAM: shikimate kinase; SPTR: shikimate kinase; PFAM: shikimate kinase; shikimate kinase complement(2909493..2910035) Spirochaeta smaragdinae DSM 11293 9490832 YP_003804420.1 CDS Spirs_2720 NC_014364.1 2910049 2910537 R KEGG: amt:Amet_4120 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2910049..2910537) Spirochaeta smaragdinae DSM 11293 9490833 YP_003804421.1 CDS Spirs_2721 NC_014364.1 2910577 2912073 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018181:IPR018484:IPR018485; KEGG: mta:Moth_2025 xylulokinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: xylulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(2910577..2912073) Spirochaeta smaragdinae DSM 11293 9490834 YP_003804422.1 CDS Spirs_2722 NC_014364.1 2912086 2913018 R COGs: COG0407 uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: sti:Sthe_2461 uroporphyrinogen decarboxylase (URO-D); PFAM: uroporphyrinogen decarboxylase (URO-D); SPTR: uroporphyrinogen decarboxylase (URO-D); PFAM: uroporphyrinogen decarboxylase (URO-D); uroporphyrinogen decarboxylase complement(2912086..2913018) Spirochaeta smaragdinae DSM 11293 9490835 YP_003804423.1 CDS Spirs_2723 NC_014364.1 2913059 2914666 R COGs: COG1574 metal-dependent hydrolase with the TIM-barrel fold; InterPro IPR013108; KEGG: aoe:Clos_0864 amidohydrolase 3; PFAM: amidohydrolase; SPTR: amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(2913059..2914666) Spirochaeta smaragdinae DSM 11293 9490836 YP_003804424.1 CDS Spirs_2724 NC_014364.1 2914718 2916112 R COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002293; KEGG: aoe:Clos_0865 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; amino acid permease-associated protein complement(2914718..2916112) Spirochaeta smaragdinae DSM 11293 9490837 YP_003804425.1 CDS Spirs_2725 NC_014364.1 2916255 2916920 R COGs: COG1802 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: tde:TDE2367 transcriptional regulator, PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(2916255..2916920) Spirochaeta smaragdinae DSM 11293 9490838 YP_003804426.1 CDS Spirs_2726 NC_014364.1 2917134 2918309 D COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168:IPR017439; KEGG: cdf:CD1086 peptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: peptidase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase 2917134..2918309 Spirochaeta smaragdinae DSM 11293 9490839 YP_003804427.1 CDS Spirs_2729 NC_014364.1 2919363 2921729 R COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: cdl:CDR20291_1994 xanthine dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: uncharacterized protein; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein complement(2919363..2921729) Spirochaeta smaragdinae DSM 11293 9490842 YP_003804428.1 CDS Spirs_2730 NC_014364.1 2921722 2922213 R COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888; KEGG: kol:Kole_2076 (2Fe-2S)-binding domain protein; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: uncharacterized protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein complement(2921722..2922213) Spirochaeta smaragdinae DSM 11293 9490843 YP_003804429.1 CDS Spirs_2731 NC_014364.1 2922277 2923257 R COGs: COG0078 ornithine carbamoyltransferase; InterPro IPR006130:IPR006132:IPR006131:IPR002082; KEGG: mta:Moth_1996 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: ornithine carbamoyltransferase; SPTR: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; probable carbamoyltransferase YgeW; ornithine carbamoyltransferase complement(2922277..2923257) Spirochaeta smaragdinae DSM 11293 9490844 YP_003804430.1 CDS Spirs_2732 NC_014364.1 2923320 2923811 R COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR006058:IPR001041:IPR002888; KEGG: mta:Moth_1961 (2Fe-2S)-binding; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: (2Fe-2S)-binding; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein complement(2923320..2923811) Spirochaeta smaragdinae DSM 11293 9490845 YP_003804431.1 CDS Spirs_2733 NC_014364.1 2923814 2924683 R COGs: COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM/CutM homologs; InterPro IPR002346:IPR016166; KEGG: pmo:Pmob_1733 molybdopterin dehydrogenase FAD-binding; PFAM: molybdopterin dehydrogenase FAD-binding; SPTR: uncharacterized protein; PFAM: FAD binding domain in molybdopterin dehydrogenase; CO dehydrogenase flavoprotein C-terminal domain; molybdopterin dehydrogenase FAD-binding protein complement(2923814..2924683) Spirochaeta smaragdinae DSM 11293 9490846 YP_003804432.1 CDS Spirs_2734 NC_014364.1 2924696 2926993 R COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: pmo:Pmob_1732 xanthine dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: xanthine dehydrogenase subunit D; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein complement(2924696..2926993) Spirochaeta smaragdinae DSM 11293 9490847 YP_003804433.1 CDS Spirs_2735 NC_014364.1 2926997 2928385 R COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR006680:IPR011778; KEGG: pmo:Pmob_1730 dihydropyrimidinase; PFAM: amidohydrolase; SPTR: dihydropyrimidinase; TIGRFAM: dihydropyrimidinase; PFAM: Amidohydrolase family; TIGRFAM: D-hydantoinase; dihydroorotase; dihydropyrimidinase complement(2926997..2928385) Spirochaeta smaragdinae DSM 11293 9490848 YP_003804434.1 CDS Spirs_2736 NC_014364.1 2928382 2929470 R COGs: COG0167 dihydroorotate dehydrogenase; InterProIPR017900:IPR001295:IPR012135:IPR001450:IPR 005720:IPR017896; KEGG: cdf:CD2077 dihydroorotate dehydrogenase, catalytic subunit; PFAM: dihydroorotate oxidase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: dihydroorotate dehydrogenase, catalytic subunit; TIGRFAM: dihydroorotate dehydrogenase; PFAM: dihydroorotate dehydrogenase; 4Fe-4S binding domain; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein; dihydroorotate dehydrogenase complement(2928382..2929470) Spirochaeta smaragdinae DSM 11293 9490849 YP_003804435.1 CDS Spirs_2737 NC_014364.1 2929683 2931155 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: sna:Snas_3125 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(2929683..2931155) Spirochaeta smaragdinae DSM 11293 9490850 YP_003804436.1 CDS Spirs_2738 NC_014364.1 2931176 2932234 R COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR002328:IPR013154:IPR013149; KEGG: tde:TDE0075 sorbitol dehydrogenase, PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: Sorbitol dehydrogenase, ; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(2931176..2932234) Spirochaeta smaragdinae DSM 11293 9490851 YP_003804437.1 CDS Spirs_2739 NC_014364.1 2932247 2933035 R COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915; KEGG: tde:TDE0076 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: uncharacterized protein; PFAM: DeoC/LacD family aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase complement(2932247..2933035) Spirochaeta smaragdinae DSM 11293 9490852 YP_003804438.1 CDS Spirs_2740 NC_014364.1 2933099 2933824 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: bpu:BPUM_3140 transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(2933099..2933824) Spirochaeta smaragdinae DSM 11293 9490853 YP_003804439.1 CDS Spirs_2741 NC_014364.1 2933989 2935485 D COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: bxe:Bxe_A3599 aldehyde dehydrogenase (acceptor); PFAM: aldehyde dehydrogenase; SPTR: aldehyde dehydrogenase (Acceptor); PFAM: aldehyde dehydrogenase family; aldehyde dehydrogenase 2933989..2935485 Spirochaeta smaragdinae DSM 11293 9490854 YP_003804440.1 CDS Spirs_2742 NC_014364.1 2935600 2936385 D KEGG: app:CAP2UW1_3692 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2935600..2936385 Spirochaeta smaragdinae DSM 11293 9490855 YP_003804441.1 CDS Spirs_2743 NC_014364.1 2936394 2937416 D COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665:IPR001035; KEGG: afw:Anae109_1570 OmpA/MotB domain-containing protein; PFAM: OmpA/MotB domain protein; SPTR: OmpA/MotB domain protein; PFAM: FecR protein; OmpA family; OmpA/MotB domain-containing protein 2936394..2937416 Spirochaeta smaragdinae DSM 11293 9490856 YP_003804442.1 CDS Spirs_2744 NC_014364.1 2937420 2939144 R COGs: COG0366 glycosidase; InterPro IPR006047:IPR006589; KEGG: afl:Aflv_2271 oligo-1,4-1,6-alpha-glucosidase (sucrase-maltase-isomaltase); PFAM: alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: alpha amylase catalytic region; PFAM: alpha amylase, catalytic domain; alpha amylase catalytic subunit complement(2937420..2939144) Spirochaeta smaragdinae DSM 11293 9490857 YP_003804443.1 CDS Spirs_2745 NC_014364.1 2939265 2940833 D COGs: COG3894 Uncharacterized metal-binding protein; InterPro IPR001041; KEGG: ate:Athe_0428 ferredoxin; PFAM: ferredoxin; SPTR: Ferredoxin; PFAM: 2Fe-2S iron-sulfur cluster binding domain; ferredoxin 2939265..2940833 Spirochaeta smaragdinae DSM 11293 9490858 YP_003804444.1 CDS Spirs_2746 NC_014364.1 2940833 2942164 D COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018771:IPR000005:IPR018060:IPR020449; KEGG: hor:Hore_15370 helix-turn-helix-domain containing protein AraC type; PFAM: helix-turn-helix- domain containing protein AraC type; transcriptional regulator, histidine kinase sensor-like; SMART: Helix-turn-helix, AraC domain; SPTR: Helix-turn-helix-domain containing protein AraC type; PFAM: Predicted histidine kinase sensor domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 2940833..2942164 Spirochaeta smaragdinae DSM 11293 9490859 YP_003804445.1 CDS Spirs_2747 NC_014364.1 2942450 2943085 D COGs: COG5012 cobalamin binding protein; InterPro IPR003759:IPR006158; KEGG: cce:Ccel_3199 methionine synthase B12-binding module cap domain protein; PFAM: cobalamin B12-binding domain protein; methionine synthase B12-binding module cap domain protein; PRIAM: methionine synthase; SPTR: uncharacterized protein; PFAM: B12 binding domain; TIGRFAM: methyltransferase cognate corrinoid proteins, Methanosarcina family; methionine synthase 2942450..2943085 Spirochaeta smaragdinae DSM 11293 9490860 YP_003804446.1 CDS Spirs_2748 NC_014364.1 2943121 2944470 D COGs: COG0407 uroporphyrinogen-III decarboxylase; InterPro IPR000257; KEGG: hor:Hore_15330 methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: uroporphyrinogen decarboxylase (URO-D); SPTR: methylamine-specific methylcobalamin coenzyme M methyltransferase; PFAM: uroporphyrinogen decarboxylase (URO-D); TIGRFAM: methyltransferase, MtaA/CmuA family; uroporphyrinogen decarboxylase 2943121..2944470 Spirochaeta smaragdinae DSM 11293 9490861 YP_003804447.1 CDS Spirs_2749 NC_014364.1 2944467 2945426 D COGs: COG0523 GTPase (G3E family); InterPro IPR003495; KEGG: hor:Hore_15320 cobalamin synthesis protein P47K; PFAM: cobalamin synthesis protein P47K; SPTR: Cobalamin synthesis protein P47K; PFAM: Cobalamin synthesis protein cobW C-terminal domain; CobW/HypB/UreG, nucleotide-binding domain; cobalamin synthesis protein P47K 2944467..2945426 Spirochaeta smaragdinae DSM 11293 9490862 YP_003804448.1 CDS Spirs_2750 NC_014364.1 2945428 2946102 D InterPro IPR004223; KEGG: hor:Hore_15340 vitamin B12 dependent methionine synthase, activation domain protein; PFAM: Vitamin B12 dependent methionine synthase activation region; SPTR: Vitamin B12 dependent methionine synthase, activation domain protein; PFAM: Vitamin B12 dependent methionine synthase, activation domain; Vitamin B12 dependent methionine synthase activation region 2945428..2946102 Spirochaeta smaragdinae DSM 11293 9490863 YP_003804449.1 CDS Spirs_2751 NC_014364.1 2946165 2947445 R COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR013027; KEGG: ppd:Ppro_2848 FAD dependent oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD dependent oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(2946165..2947445) Spirochaeta smaragdinae DSM 11293 9490864 YP_003804450.1 CDS Spirs_2752 NC_014364.1 2947445 2947945 R COGs: COG0440 acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR019455:IPR004789; KEGG: mtp:Mthe_0111 acetolactate synthase, small subunit; PFAM: acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein; SPTR: acetolactate synthase, small subunit; TIGRFAM: acetolactate synthase, small subunit; PFAM: Small subunit of acetolactate synthase; ACT domain; TIGRFAM: acetolactate synthase, small subunit; acetolactate synthase, small subunit complement(2947445..2947945) Spirochaeta smaragdinae DSM 11293 9490865 YP_003804451.1 CDS Spirs_2753 NC_014364.1 2947942 2949615 R COGs: COG0028 thiamine pyrophosphate-requiring protein; InterProIPR000399:IPR012001:IPR012000:IPR011766:IPR 012846; KEGG: mac:MA3792 acetolactate synthase 3 catalytic subunit; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding; SPTR: acetolactate synthase; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme, central domain; thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase large subunit; acetolactate synthase, large subunit, biosynthetic type complement(2947942..2949615) Spirochaeta smaragdinae DSM 11293 9490866 YP_003804452.1 CDS Spirs_2754 NC_014364.1 2949829 2950422 D COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: fsu:Fisuc_1116 protein of unknown function DUF208; PFAM: protein of unknown function DUF208; SPTR: uncharacterized protein; PFAM: Uncharacterized BCR, COG1636; hypothetical protein 2949829..2950422 Spirochaeta smaragdinae DSM 11293 9490867 YP_003804453.1 CDS Spirs_2755 NC_014364.1 2950391 2951608 R COGs: COG0105 nucleoside diphosphate kinase; InterPro IPR001564; KEGG: min:Minf_1367 nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; SMART: nucleoside diphosphate kinase; SPTR: nucleoside diphosphate kinase; PFAM: nucleoside diphosphate kinase; nucleoside diphosphate kinase complement(2950391..2951608) Spirochaeta smaragdinae DSM 11293 9490868 YP_003804454.1 CDS Spirs_2756 NC_014364.1 2951637 2952860 R COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR001917:IPR004839; KEGG: dth:DICTH_0538 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: aminotransferase class I and II; PRIAM: 8-amino-7-oxononanoate synthase; SPTR: 2-amino-3-ketobutyrate coenzyme A ligase; PFAM: Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 8-amino-7-oxononanoate synthase complement(2951637..2952860) Spirochaeta smaragdinae DSM 11293 9490869 YP_003804455.1 CDS Spirs_2757 NC_014364.1 2952857 2953702 R COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347; KEGG: dol:Dole_1506 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(2952857..2953702) Spirochaeta smaragdinae DSM 11293 9490870 YP_003804456.1 CDS Spirs_2758 NC_014364.1 2953699 2954223 R COGs: COG1846 transcriptional regulators; InterPro IPR000835; KEGG: rci:RCIX763 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: transcription regulator (MarR family); PFAM: MarR family; MarR family transcriptional regulator complement(2953699..2954223) Spirochaeta smaragdinae DSM 11293 9490871 YP_003804457.1 CDS Spirs_2759 NC_014364.1 2954363 2955565 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR002933:IPR011650:IPR001261; KEGG: mta:Moth_1646 peptidase; PFAM: peptidase dimerisation domain protein; peptidase M20; SPTR: peptidase dimerisation; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: selenium metabolism hydrolase; peptidase dimerization domain-containing protein 2954363..2955565 Spirochaeta smaragdinae DSM 11293 9490872 YP_003804458.1 CDS Spirs_2760 NC_014364.1 2955617 2956996 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR004358:IPR 005467; KEGG: rrs:RoseRS_3736 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase complement(2955617..2956996) Spirochaeta smaragdinae DSM 11293 9490873 YP_003804459.1 CDS Spirs_2761 NC_014364.1 2956989 2957708 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: chl:Chy400_4163 two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator complement(2956989..2957708) Spirochaeta smaragdinae DSM 11293 9490874 YP_003804460.1 CDS Spirs_2762 NC_014364.1 2957782 2959332 D COGs: COG0514 Superfamily II DNA helicase; InterProIPR018329:IPR011545:IPR001650:IPR014021:IPR 014001; KEGG: tde:TDE0435 ATP-dependent DNA helicase RecQ; PFAM: DEAD/DEAH box helicase domain protein; helicase; SMART: DEAD-like helicase ; helicase domain protein; SPTR: ATP-dependent DNA helicase, RecQ family; TIGRFAM: ATP-dependent DNA helicase, RecQ family; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase, RecQ family 2957782..2959332 Spirochaeta smaragdinae DSM 11293 9490875 YP_003804461.1 CDS Spirs_2763 NC_014364.1 2959238 2960215 R COGs: COG0791 cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064:IPR003409; KEGG: gyc:GYMC61_1279 NLP/P60 protein; PFAM: NLP/P60 protein; MORN repeat-containing protein; SPTR: uncharacterized protein; PFAM: NlpC/P60 family; MORN repeat; NLP/P60 protein complement(2959238..2960215) Spirochaeta smaragdinae DSM 11293 9490876 YP_003804462.1 CDS Spirs_2764 NC_014364.1 2960219 2961319 R COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342; KEGG: sli:Slin_0013 mandelate racemase/muconate lactonizing protein; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: mandelate racemase/muconate lactonizing protein; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; mandelate racemase / muconate lactonizing enzyme, N-terminal domain; mandelate racemase/muconate lactonizing protein complement(2960219..2961319) Spirochaeta smaragdinae DSM 11293 9490877 YP_003804463.1 CDS Spirs_2765 NC_014364.1 2961474 2962595 D InterPro IPR000182; KEGG: pdi:BDI_3346 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; GCN5-like N-acetyltransferase 2961474..2962595 Spirochaeta smaragdinae DSM 11293 9490878 YP_003804464.1 CDS Spirs_2766 NC_014364.1 2962610 2963563 R COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: kol:Kole_0462 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2962610..2963563) Spirochaeta smaragdinae DSM 11293 9490879 YP_003804465.1 CDS Spirs_2767 NC_014364.1 2963563 2964636 R COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: mta:Moth_1951 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(2963563..2964636) Spirochaeta smaragdinae DSM 11293 9490880 YP_003804466.1 CDS Spirs_2768 NC_014364.1 2964642 2966222 R COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003439:IPR003593:IPR017871; KEGG: mta:Moth_1952 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(2964642..2966222) Spirochaeta smaragdinae DSM 11293 9490881 YP_003804467.1 CDS Spirs_2769 NC_014364.1 2966306 2967433 R COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: hmo:HM1_2695 membrane protein, bmp family; PFAM: basic membrane lipoprotein; SPTR: membrane protein, bmp family; PFAM: Basic membrane protein; basic membrane lipoprotein complement(2966306..2967433) Spirochaeta smaragdinae DSM 11293 9490882 YP_003804468.1 CDS Spirs_2770 NC_014364.1 2967548 2970022 R COGs: COG0527 Aspartokinase; InterProIPR001341:IPR001048:IPR002912:IPR005106:IPR 001342:IPR011147:IPR001412:IPR019811; KEGG: sru:SRU_0691 bifunctional aspartokinase I/homeserine dehydrogenase I; PFAM: homoserine dehydrogenase; homoserine dehydrogenase NAD-binding; aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; SPTR: Bifunctional aspartokinase/homoserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase, NAD binding domain; homoserine dehydrogenase; ACT domain; Amino acid kinase family; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; aspartate kinase; aspartate kinase complement(2967548..2970022) Spirochaeta smaragdinae DSM 11293 9490883 YP_003804469.1 CDS Spirs_2771 NC_014364.1 2970129 2970356 R InterPro IPR001383; KEGG: hor:Hore_10080 ribosomal protein L28; PFAM: ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: ribosomal protein L28; PFAM: ribosomal L28 family; TIGRFAM: ribosomal protein L28; 50S ribosomal protein L28 complement(2970129..2970356) Spirochaeta smaragdinae DSM 11293 9490884 YP_003804470.1 CDS Spirs_2772 NC_014364.1 2970449 2972185 R KEGG: btu:BT0536A hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2970449..2972185) Spirochaeta smaragdinae DSM 11293 9490885 YP_003804471.1 CDS Spirs_2773 NC_014364.1 2972189 2972962 R KEGG: rer:RER_10650 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(2972189..2972962) Spirochaeta smaragdinae DSM 11293 9490886 YP_003804472.1 CDS Spirs_2774 NC_014364.1 2972999 2973565 D KEGG: caa:Caka_1562 helicase C2; SPTR: Expressed protein; hypothetical protein 2972999..2973565 Spirochaeta smaragdinae DSM 11293 9490887 YP_003804473.1 CDS Spirs_2775 NC_014364.1 2973547 2975244 R COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR008207:IPR001789; KEGG: alv:Alvin_0590 response regulator receiver modulated diguanylate cyclase; PFAM: GGDEF domain containing protein; Hpt domain protein; response regulator receiver; SMART: GGDEF domain containing protein; Hpt domain protein; response regulator receiver; SPTR: Response regulator receiver modulated diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; Response regulator receiver domain; Hpt domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; response regulator receiver modulated diguanylate cyclase complement(2973547..2975244) Spirochaeta smaragdinae DSM 11293 9490888 YP_003804474.1 CDS Spirs_2776 NC_014364.1 2975325 2975789 D COGs: COG1321 Mn-dependent transcriptional regulator protein; InterPro IPR001367; KEGG: sfu:Sfum_3768 DtxR family iron dependent repressor; PFAM: iron dependent repressor; SMART: iron dependent repressor; SPTR: Iron (metal) dependent repressor, DtxR family; PFAM: Iron dependent repressor, metal binding and dimerisation domain; Iron dependent repressor, N-terminal DNA binding domain; iron (metal) dependent repressor 2975325..2975789 Spirochaeta smaragdinae DSM 11293 9490889 YP_003804475.1 CDS Spirs_2777 NC_014364.1 2975755 2976408 R COGs: COG0177 endoIII-related endonuclease; InterPro IPR005759:IPR003265:IPR003651:IPR004035; KEGG: rmr:Rmar_1446 endonuclease III; PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; iron-sulfur cluster loop; SPTR: endonuclease III; TIGRFAM: endonuclease III; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; TIGRFAM: endonuclease III; endonuclease III complement(2975755..2976408) Spirochaeta smaragdinae DSM 11293 9490890 YP_003804476.1 CDS Spirs_2778 NC_014364.1 2976748 2977998 D COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: ppd:Ppro_3565 phage integrase family protein; PFAM: integrase family protein; SPTR: Integrase family protein; PFAM: Phage integrase family; integrase family protein 2976748..2977998 Spirochaeta smaragdinae DSM 11293 9490893 YP_003804477.1 CDS Spirs_2779 NC_014364.1 2978103 2978576 R InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator complement(2978103..2978576) Spirochaeta smaragdinae DSM 11293 9490894 YP_003804478.1 CDS Spirs_2781 NC_014364.1 2978805 2979119 D KEGG: noc:Noc_0665 excisionase/Xis, DNA-binding; SPTR: uncharacterized protein; TIGRFAM: DNA binding domain, excisionase family; hypothetical protein 2978805..2979119 Spirochaeta smaragdinae DSM 11293 9490896 YP_003804479.1 CDS Spirs_2782 NC_014364.1 2979484 2979939 R KEGG: vfi:VF_A0376 hypothetical protein; SPTR: P93 protein; hypothetical protein complement(2979484..2979939) Spirochaeta smaragdinae DSM 11293 9490897 YP_003804480.1 CDS Spirs_2783 NC_014364.1 2980070 2980450 R InterPro IPR001387; KEGG: tde:TDE1170 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix; helix-turn-helix domain-containing protein complement(2980070..2980450) Spirochaeta smaragdinae DSM 11293 9490898 YP_003804481.1 CDS Spirs_2784 NC_014364.1 2981047 2981250 D KEGG: sen:SACE_3576 integral membrane protein MviN; SPTR: integral membrane protein MviN; hypothetical protein 2981047..2981250 Spirochaeta smaragdinae DSM 11293 9490899 YP_003804482.1 CDS Spirs_2785 NC_014364.1 2981865 2982401 D KEGG: eck:EC55989_2618 hypothetical protein; SPTR: Gp49; PFAM: protein of unknown function (DUF2829); hypothetical protein 2981865..2982401 Spirochaeta smaragdinae DSM 11293 9490900 YP_003804483.1 CDS Spirs_2786 NC_014364.1 2982398 2982652 D KEGG: ssc:100153677 similar to CLIP1 protein; SPTR: CLIP-170; hypothetical protein 2982398..2982652 Spirochaeta smaragdinae DSM 11293 9490901 YP_003804484.1 CDS Spirs_2787 NC_014364.1 2982649 2983740 D KEGG: sit:TM1040_1687 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2982649..2983740 Spirochaeta smaragdinae DSM 11293 9490902 YP_003804485.1 CDS Spirs_2788 NC_014364.1 2983755 2984405 D KEGG: nvi:100118525 similar to CG18255-PA; SPTR: uncharacterized protein; hypothetical protein 2983755..2984405 Spirochaeta smaragdinae DSM 11293 9490903 YP_003804486.1 CDS Spirs_2789 NC_014364.1 2984410 2985048 D KEGG: bpd:BURPS668_A2378 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2984410..2985048 Spirochaeta smaragdinae DSM 11293 9490904 YP_003804487.1 CDS Spirs_2790 NC_014364.1 2985045 2985518 D KEGG: pan:PODANSg7154 hypothetical protein; SPTR: Predicted CDS Pa_6_6170; hypothetical protein 2985045..2985518 Spirochaeta smaragdinae DSM 11293 9490905 YP_003804488.1 CDS Spirs_2791 NC_014364.1 2985528 2985974 D KEGG: pdi:BDI_0857 recombination protein; SPTR: uncharacterized protein; hypothetical protein 2985528..2985974 Spirochaeta smaragdinae DSM 11293 9490906 YP_003804489.1 CDS Spirs_2792 NC_014364.1 2985984 2986526 D COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: tde:TDE1677 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein 2985984..2986526 Spirochaeta smaragdinae DSM 11293 9490907 YP_003804490.1 CDS Spirs_2793 NC_014364.1 2986539 2987651 D KEGG: hha:Hhal_0451 TonB family protein; SPTR: Predicted protein; hypothetical protein 2986539..2987651 Spirochaeta smaragdinae DSM 11293 9490908 YP_003804491.1 CDS Spirs_2794 NC_014364.1 2987656 2988057 D KEGG: bbo:BBOV_I000040 variant erythrocyte surface antigen-1 subunit beta; SPTR: uncharacterized protein; hypothetical protein 2987656..2988057 Spirochaeta smaragdinae DSM 11293 9490909 YP_003804492.1 CDS Spirs_2795 NC_014364.1 2988041 2988259 D KEGG: smf:Smon_1264 RNA-binding S4 domain protein; SPTR: RNA-binding S4 domain protein; hypothetical protein 2988041..2988259 Spirochaeta smaragdinae DSM 11293 9490910 YP_003804493.1 CDS Spirs_2796 NC_014364.1 2988256 2988462 D hypothetical protein 2988256..2988462 Spirochaeta smaragdinae DSM 11293 9490911 YP_003804494.1 CDS Spirs_2797 NC_014364.1 2988462 2989181 D KEGG: tet:TTHERM_00437410 hypothetical protein; SPTR: Predicted protein; hypothetical protein 2988462..2989181 Spirochaeta smaragdinae DSM 11293 9490912 YP_003804495.1 CDS Spirs_2798 NC_014364.1 2989141 2990028 D KEGG: sus:acid_5400 hypothetical protein; SPTR: uncharacterized protein; PFAM: terminase-like family; hypothetical protein 2989141..2990028 Spirochaeta smaragdinae DSM 11293 9490913 YP_003804496.1 CDS Spirs_2799 NC_014364.1 2990048 2990725 D KEGG: sus:acid_6277 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2990048..2990725 Spirochaeta smaragdinae DSM 11293 9490914 YP_003804497.1 CDS Spirs_2800 NC_014364.1 2990697 2990873 D KEGG: sne:SPN23F_15510 hypothetical protein; hypothetical protein 2990697..2990873 Spirochaeta smaragdinae DSM 11293 9490915 YP_003804498.1 CDS Spirs_2801 NC_014364.1 2990900 2991442 D KEGG: xac:XAC2732 hypothetical protein; SPTR: Predicted small integral membrane protein; hypothetical protein 2990900..2991442 Spirochaeta smaragdinae DSM 11293 9490916 YP_003804499.1 CDS Spirs_2802 NC_014364.1 2991609 2991938 D KEGG: nph:NP3874A restriction/modification enzyme; SPTR: Probable restriction/modification enzyme; hypothetical protein 2991609..2991938 Spirochaeta smaragdinae DSM 11293 9490917 YP_003804500.1 CDS Spirs_2803 NC_014364.1 2991948 2993630 D KEGG: tde:TDE1152 head-to-tail joining protein, SPTR: Head-to-tail joining protein, ; PFAM: bacteriophage head to tail connecting protein; head-to-tail joining protein 2991948..2993630 Spirochaeta smaragdinae DSM 11293 9490918 YP_003804501.1 CDS Spirs_2804 NC_014364.1 2993627 2993929 D KEGG: tde:TDE1151 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2993627..2993929 Spirochaeta smaragdinae DSM 11293 9490919 YP_003804502.1 CDS Spirs_2805 NC_014364.1 2993926 2994732 D KEGG: tde:TDE1150 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2993926..2994732 Spirochaeta smaragdinae DSM 11293 9490920 YP_003804503.1 CDS Spirs_2806 NC_014364.1 2994744 2995730 D KEGG: ect:ECIAI39_2677 conserved hypothetical protein from phage origin; SPTR: uncharacterized protein; hypothetical protein 2994744..2995730 Spirochaeta smaragdinae DSM 11293 9490921 YP_003804504.1 CDS Spirs_2807 NC_014364.1 2995745 2996119 D KEGG: ecv:APECO1_4045 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2995745..2996119 Spirochaeta smaragdinae DSM 11293 9490922 YP_003804505.1 CDS Spirs_2808 NC_014364.1 2996128 2996442 D KEGG: fnu:FN0250 hypothetical protein; SPTR: Predicted protein; hypothetical protein 2996128..2996442 Spirochaeta smaragdinae DSM 11293 9490923 YP_003804506.1 CDS Spirs_2809 NC_014364.1 2996452 2997045 D KEGG: dsa:Desal_1440 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2996452..2997045 Spirochaeta smaragdinae DSM 11293 9490924 YP_003804507.1 CDS Spirs_2810 NC_014364.1 2997042 2998754 D KEGG: azl:AZL_024820 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2997042..2998754 Spirochaeta smaragdinae DSM 11293 9490925 YP_003804508.1 CDS Spirs_2811 NC_014364.1 2998751 2999638 D KEGG: aas:Aasi_0826 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 2998751..2999638 Spirochaeta smaragdinae DSM 11293 9490926 YP_003804509.1 CDS Spirs_2812 NC_014364.1 2999654 3001600 D KEGG: ptm:GSPATT00013086001 hypothetical protein; SPTR: chromosome undetermined scaffold_36, whole genome shotgun sequence; hypothetical protein 2999654..3001600 Spirochaeta smaragdinae DSM 11293 9490927 YP_003804510.1 CDS Spirs_2813 NC_014364.1 3001597 3007842 D KEGG: tde:TDE1142 phage minor structural protein, SPTR: Phage minor structural protein; hypothetical protein 3001597..3007842 Spirochaeta smaragdinae DSM 11293 9490928 YP_003804511.1 CDS Spirs_2814 NC_014364.1 3007835 3011446 D InterPro IPR008160:IPR003961:IPR001680; KEGG: cpf:CPF_1202 triple helix repeat-containing collagen; PFAM: Collagen triple helix repeat; SPTR: collagen; PFAM: WD domain, G-beta repeat; Collagen triple helix repeat (20 copies); collagen 3007835..3011446 Spirochaeta smaragdinae DSM 11293 9490929 YP_003804512.1 CDS Spirs_2815 NC_014364.1 3011443 3012054 D KEGG: bam:Bamb_1861 bacteriophage-acquired protein; SPTR: uncharacterized protein; hypothetical protein 3011443..3012054 Spirochaeta smaragdinae DSM 11293 9490930 YP_003804513.1 CDS Spirs_2816 NC_014364.1 3012059 3012292 D KEGG: tva:TVAG_483670 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3012059..3012292 Spirochaeta smaragdinae DSM 11293 9490931 YP_003804514.1 CDS Spirs_2817 NC_014364.1 3012298 3012777 D KEGG: gga:420817 ATPase, class II, type 9B; SPTR: uncharacterized protein; hypothetical protein 3012298..3012777 Spirochaeta smaragdinae DSM 11293 9490932 YP_003804515.1 CDS Spirs_2818 NC_014364.1 3012774 3012995 D KEGG: bpf:BpOF4_16720 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3012774..3012995 Spirochaeta smaragdinae DSM 11293 9490933 YP_003804516.1 CDS Spirs_2819 NC_014364.1 3013013 3013402 D KEGG: acp:A2cp1_0147 methyltransferase type 11; SPTR: methyltransferase type 11; hypothetical protein 3013013..3013402 Spirochaeta smaragdinae DSM 11293 9490934 YP_003804517.1 CDS Spirs_2820 NC_014364.1 3013516 3013632 D hypothetical protein 3013516..3013632 Spirochaeta smaragdinae DSM 11293 9490935 YP_003804518.1 CDS Spirs_2821 NC_014364.1 3013650 3014759 D KEGG: cpi:Cpin_1539 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3013650..3014759 Spirochaeta smaragdinae DSM 11293 9490936 YP_003804519.1 CDS Spirs_2822 NC_014364.1 3014831 3015292 D KEGG: scb:SCAB_73091 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3014831..3015292 Spirochaeta smaragdinae DSM 11293 9490937 YP_003804520.1 CDS Spirs_2823 NC_014364.1 3015600 3016505 R KEGG: cbl:CLK_0548 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2971); hypothetical protein complement(3015600..3016505) Spirochaeta smaragdinae DSM 11293 9490938 YP_003804521.1 CDS Spirs_2824 NC_014364.1 3016737 3018218 R COGs: COG4916 Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain; InterPro IPR003593; KEGG: cyc:PCC7424_5586 ATPase; SMART: ATPase AAA; SPTR: ATPase; ATPase AAA complement(3016737..3018218) Spirochaeta smaragdinae DSM 11293 9490939 YP_003804522.1 CDS Spirs_2825 NC_014364.1 3019175 3020359 R COGs: COG3328 transposase and inactivated derivatives; InterPro IPR001207; KEGG: glo:Glov_3450 transposase mutator type; PFAM: transposase mutator type; SPTR: transposase mutator type; PFAM: transposase, Mutator family; transposase mutator type complement(3019175..3020359) Spirochaeta smaragdinae DSM 11293 9490940 YP_003804523.1 CDS Spirs_2826 NC_014364.1 3021004 3021747 R COGs: COG5470 conserved hypothetical protein; InterPro IPR010753:IPR000182; KEGG: cac:CAC2560 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; protein of unknown function DUF1330; SPTR: Predicted acetyltransferase; PFAM: acetyltransferase (GNAT) family; protein of unknown function (DUF1330); GCN5-like N-acetyltransferase complement(3021004..3021747) Spirochaeta smaragdinae DSM 11293 9490941 YP_003804524.1 CDS Spirs_2827 NC_014364.1 3021995 3022825 R COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: lbf:LBF_0939 Zn-dependent hydrolase; PRIAM: beta-lactamase; SPTR: metallo-b-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(3021995..3022825) Spirochaeta smaragdinae DSM 11293 9490942 YP_003804525.1 CDS Spirs_2828 NC_014364.1 3023181 3023453 R InterPro IPR007712; KEGG: tte:TTE2029 hypothetical protein; PFAM: plasmid stabilization system; SPTR: uncharacterized protein; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family; plasmid stabilization system complement(3023181..3023453) Spirochaeta smaragdinae DSM 11293 9490943 YP_003804526.1 CDS Spirs_2829 NC_014364.1 3023446 3023688 R KEGG: pph:Ppha_0977 hypothetical protein; SPTR: Helix-turn-helix protein, CopG; hypothetical protein complement(3023446..3023688) Spirochaeta smaragdinae DSM 11293 9490944 YP_003804527.1 CDS Spirs_2830 NC_014364.1 3024088 3024474 R COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: rle:RL3220 hypothetical protein; PFAM: helix-turn-helix HxlR type; SPTR: uncharacterized protein; PFAM: HxlR-like helix-turn-helix; HxlR family transcriptional regulator complement(3024088..3024474) Spirochaeta smaragdinae DSM 11293 9490945 YP_003804528.1 CDS Spirs_2831 NC_014364.1 3024680 3025591 D COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR013154:IPR013149:IPR002364; KEGG: ami:Amir_3171 alcohol dehydrogenase zinc-binding domain protein; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; SPTR: alcohol dehydrogenase zinc-binding domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein 3024680..3025591 Spirochaeta smaragdinae DSM 11293 9490946 YP_003804529.1 CDS Spirs_2832 NC_014364.1 3025715 3025984 R InterPro IPR007419; KEGG: pho:PH1750.1n hypothetical protein; PFAM: BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; BFD domain-containing protein (2Fe-2S)-binding domain-containing protein complement(3025715..3025984) Spirochaeta smaragdinae DSM 11293 9490947 YP_003804530.1 CDS Spirs_2833 NC_014364.1 3025981 3027639 R COGs: COG0492 thioredoxin reductase; InterProIPR013027:IPR001450:IPR000103:IPR017896:IPR 017900; KEGG: ckr:CKR_1805 hypothetical protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S binding domain; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(3025981..3027639) Spirochaeta smaragdinae DSM 11293 9490948 YP_003804531.1 CDS Spirs_2834 NC_014364.1 3027626 3027937 R InterPro IPR001041; KEGG: ckl:CKL_2061 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3027626..3027937) Spirochaeta smaragdinae DSM 11293 9490949 YP_003804532.1 CDS Spirs_2835 NC_014364.1 3027934 3029133 R COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650:IPR017439; KEGG: sti:Sthe_2535 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase complement(3027934..3029133) Spirochaeta smaragdinae DSM 11293 9490950 YP_003804533.1 CDS Spirs_2836 NC_014364.1 3029161 3030531 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: dae:Dtox_1189 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(3029161..3030531) Spirochaeta smaragdinae DSM 11293 9490951 YP_003804534.1 CDS Spirs_2837 NC_014364.1 3030524 3031384 R COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: tte:TTE1365 metal-dependent hydrolase of the TIM-barrel fold; PFAM: amidohydrolase 2; SPTR: Amidohydrolase family protein; PFAM: Amidohydrolase; amidohydrolase 2 complement(3030524..3031384) Spirochaeta smaragdinae DSM 11293 9490952 YP_003804535.1 CDS Spirs_2838 NC_014364.1 3031454 3032212 R KEGG: cyt:cce_1529 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1393); hypothetical protein complement(3031454..3032212) Spirochaeta smaragdinae DSM 11293 9490953 YP_003804536.1 CDS Spirs_2839 NC_014364.1 3032222 3033097 R COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: pth:PTH_1658 ABC-type cobalt transporter, ATPase component; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC-type cobalt transporter, ATPase component; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; ABC transporter complement(3032222..3033097) Spirochaeta smaragdinae DSM 11293 9490954 YP_003804537.1 CDS Spirs_2840 NC_014364.1 3033094 3033966 R COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: tsi:TSIB_1505 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(3033094..3033966) Spirochaeta smaragdinae DSM 11293 9490955 YP_003804538.1 CDS Spirs_2841 NC_014364.1 3033976 3034782 R COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: tte:TTE1588 ABC-type cobalt transporter, permease CbiQ and related transporters; PFAM: cobalt transporter; SPTR: Cobalt transport protein; PFAM: Cobalt transporter; cobalt transporter complement(3033976..3034782) Spirochaeta smaragdinae DSM 11293 9490956 YP_003804539.1 CDS Spirs_2842 NC_014364.1 3034775 3035977 R COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR006076; KEGG: sti:Sthe_0592 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: uncharacterized protein; PFAM: FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(3034775..3035977) Spirochaeta smaragdinae DSM 11293 9490957 YP_003804540.1 CDS Spirs_2843 NC_014364.1 3035974 3036789 R COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: cac:CAC3337 amidohodrolase; PFAM: amidohydrolase 2; SPTR: Predicted amidohodrolase (dihydroorotase family); PFAM: Amidohydrolase; amidohydrolase 2 complement(3035974..3036789) Spirochaeta smaragdinae DSM 11293 9490958 YP_003804541.1 CDS Spirs_2844 NC_014364.1 3036793 3037515 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: cwo:Cwoe_2778 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(3036793..3037515) Spirochaeta smaragdinae DSM 11293 9490959 YP_003804542.1 CDS Spirs_2845 NC_014364.1 3037573 3038388 R COGs: COG1410 methionine synthase I cobalamin-binding domain; InterPro IPR000489; KEGG: mta:Moth_2115 methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase; PFAM: dihydropteroate synthase DHPS; SPTR: 5-methyltetrahydrofolate--homocysteine S-methyltransferase; PFAM: Pterin binding enzyme; dihydropteroate synthase DHPS complement(3037573..3038388) Spirochaeta smaragdinae DSM 11293 9490960 YP_003804543.1 CDS Spirs_2846 NC_014364.1 3038394 3039362 R COGs: COG3252 Methenyltetrahydromethanopterin cyclohydrolase; InterPro IPR003209; KEGG: mka:MK0625 N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; PFAM: Methenyltetrahydromethanopterin cyclohydrolase; PRIAM: Methenyltetrahydromethanopterin cyclohydrolase; SPTR: Methenyltetrahydromethanopterin cyclohydrolase; TIGRFAM: methenyltetrahydromethanopterin cyclohydrolase; PFAM: Cyclohydrolase (MCH); TIGRFAM: methenyltetrahydromethanopterin cyclohydrolase; methenyltetrahydromethanopterin cyclohydrolase complement(3038394..3039362) Spirochaeta smaragdinae DSM 11293 9490961 YP_003804544.1 CDS Spirs_2847 NC_014364.1 3039379 3040134 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: bcy:Bcer98_2444 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulators-like protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(3039379..3040134) Spirochaeta smaragdinae DSM 11293 9490962 YP_003804545.1 CDS Spirs_2848 NC_014364.1 3040265 3041350 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR001789:IPR011495:IPR003594:IPR005467; KEGG: dsa:Desal_1716 signal transduction histidine kinase; PFAM: response regulator receiver; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; signal transduction histidine kinase 3040265..3041350 Spirochaeta smaragdinae DSM 11293 9490963 YP_003804546.1 CDS Spirs_2849 NC_014364.1 3041424 3043685 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR013656:IPR013767:IPR003661:IPR 003594:IPR001789:IPR004358:IPR005467:IPR000700:IPR001610; KEGG: glo:Glov_3522 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; PAC repeat-containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor hybrid histidine kinase 3041424..3043685 Spirochaeta smaragdinae DSM 11293 9490964 YP_003804547.1 CDS Spirs_2850 NC_014364.1 3043682 3045805 R COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006656:IPR006657:IPR006655; KEGG: dal:Dalk_4207 molybdopterin oxidoreductase; PFAM: molybdopterin oxidoreductase; molybdopterin oxidoreductase Fe4S4 region; molydopterin dinucleotide-binding region; SPTR: Molybdopterin oxidoreductase; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain; TIGRFAM: molybdopterin guanine dinucleotide-containing S/N-oxide reductases; molybdopterin oxidoreductase complement(3043682..3045805) Spirochaeta smaragdinae DSM 11293 9490965 YP_003804548.1 CDS Spirs_2851 NC_014364.1 3046107 3047780 D COGs: COG1061 DNA or RNA helicase of superfamily II; InterProIPR006935:IPR001650:IPR001161:IPR014021:IPR 014001; KEGG: tde:TDE2721 helicase domain-containing protein; PFAM: helicase; type III restriction protein res subunit; SMART: DEAD-like helicase ; helicase domain protein; SPTR: Helicase domain protein; PFAM: Helicase conserved C-terminal domain; type III restriction enzyme, res subunit; helicase 3046107..3047780 Spirochaeta smaragdinae DSM 11293 9490966 YP_003804549.1 CDS Spirs_2852 NC_014364.1 3047784 3049814 D KEGG: tde:TDE0193 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3047784..3049814 Spirochaeta smaragdinae DSM 11293 9490967 YP_003804550.1 CDS Spirs_2853 NC_014364.1 3049765 3051243 R COGs: COG0169 shikimate 5-dehydrogenase; InterPro IPR011342:IPR001381:IPR013708:IPR006151; KEGG: psl:Psta_4018 shikimate 5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain protein; dehydroquinase class I; shikimate/quinate 5-dehydrogenase; SPTR: 3-dehydroquinate dehydratase, type 1, /shikimate 5-dehydrogenase, ; TIGRFAM: shikimate 5-dehydrogenase; PFAM: shikimate dehydrogenase substrate binding domain; type I 3-dehydroquinase; shikimate / quinate 5-dehydrogenase; TIGRFAM: 3-dehydroquinate dehydratase, type I; shikimate 5-dehydrogenase; shikimate 5-dehydrogenase complement(3049765..3051243) Spirochaeta smaragdinae DSM 11293 9490968 YP_003804551.1 CDS Spirs_2854 NC_014364.1 3051266 3051787 R KEGG: mmr:Mmar10_2740 alpha-glucosidase; SPTR: alpha-glucosidase; hypothetical protein complement(3051266..3051787) Spirochaeta smaragdinae DSM 11293 9490969 YP_003804552.1 CDS Spirs_2855 NC_014364.1 3051789 3053555 R InterPro IPR013105:IPR019734:IPR013026; KEGG: tpp:TPASS_0622 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; SPTR: uncharacterized protein; hypothetical protein complement(3051789..3053555) Spirochaeta smaragdinae DSM 11293 9490970 YP_003804553.1 CDS Spirs_2856 NC_014364.1 3053572 3054786 R COGs: COG0538 isocitrate dehydrogenase; InterPro IPR004439:IPR001804:IPR019818; KEGG: aac:Aaci_2348 isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: isocitrate dehydrogenase (NADP(+)); SPTR: isocitrate dehydrogenase [NADP]; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NADP-dependent, prokaryotic type; NADP-dependent isocitrate dehydrogenase complement(3053572..3054786) Spirochaeta smaragdinae DSM 11293 9490971 YP_003804554.1 CDS Spirs_2857 NC_014364.1 3054874 3055986 D KEGG: tde:TDE2150 hypothetical protein; SPTR: Tetratricopeptide repeat domain protein; hypothetical protein 3054874..3055986 Spirochaeta smaragdinae DSM 11293 9490972 YP_003804555.1 CDS Spirs_2858 NC_014364.1 3055967 3057349 D InterPro IPR008258:IPR018392:IPR002482; KEGG: tde:TDE2149 Slt family transglycosylase; PFAM: lytic transglycosylase catalytic; peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: transglycosylase, SLT family; PFAM: transglycosylase SLT domain; LysM domain; lytic transglycosylase 3055967..3057349 Spirochaeta smaragdinae DSM 11293 9490973 YP_003804556.1 CDS Spirs_2859 NC_014364.1 3057363 3058232 D KEGG: tde:TDE2148 OmpA family protein; SPTR: OmpA family protein; OmpA family protein 3057363..3058232 Spirochaeta smaragdinae DSM 11293 9490974 YP_003804557.1 CDS Spirs_2860 NC_014364.1 3058265 3059575 D KEGG: tde:TDE1404 lipoprotein; SPTR: Lipoprotein, ; PFAM: Bacterial SH3 domain; lipoprotein 3058265..3059575 Spirochaeta smaragdinae DSM 11293 9490975 YP_003804558.1 CDS Spirs_2861 NC_014364.1 3059577 3061535 D COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003439:IPR003593:IPR017871; KEGG: tde:TDE1403 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 3059577..3061535 Spirochaeta smaragdinae DSM 11293 9490976 YP_003804559.1 CDS Spirs_2862 NC_014364.1 3061542 3061778 D KEGG: dth:DICTH_0971 hypothetical protein; SPTR: PTS system, glucose-specific IIABC component; hypothetical protein 3061542..3061778 Spirochaeta smaragdinae DSM 11293 9490977 YP_003804560.1 CDS Spirs_2863 NC_014364.1 3061791 3062396 D COGs: COG0424 nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: sth:STH370 septum formation protein Maf; PFAM: Maf family protein; SPTR: Maf-like protein STH370; TIGRFAM: maf protein; PFAM: Maf-like protein; TIGRFAM: MAF protein; maf protein 3061791..3062396 Spirochaeta smaragdinae DSM 11293 9490978 YP_003804561.1 CDS Spirs_2864 NC_014364.1 3062474 3063376 D COGs: COG0052 ribosomal protein S2; InterPro IPR005706:IPR001865:IPR018130; KEGG: tde:TDE2347 30S ribosomal protein S2; PFAM: ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type; 30S ribosomal protein S2 3062474..3063376 Spirochaeta smaragdinae DSM 11293 9490979 YP_003804562.1 CDS Spirs_2865 NC_014364.1 3063388 3064230 D COGs: COG0264 translation elongation factor Ts; InterPro IPR001816:IPR000449:IPR014039:IPR018101; KEGG: tde:TDE2346 elongation factor Ts; PFAM: translation elongation factor EFTs/EF1B dimerisation; ubiquitin-associated- domain-containing protein; SPTR: Elongation factor Ts; TIGRFAM: translation elongation factor Ts; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts; translation elongation factor Ts 3063388..3064230 Spirochaeta smaragdinae DSM 11293 9490980 YP_003804563.1 CDS Spirs_2866 NC_014364.1 3064296 3064850 D COGs: COG0233 ribosome recycling factor; InterPro IPR002661:IPR015998; KEGG: tde:TDE2345 ribosome recycling factor; PFAM: ribosome recycling factor; SPTR: ribosome recycling factor; TIGRFAM: ribosome recycling factor; PFAM: ribosome recycling factor; TIGRFAM: ribosome recycling factor; ribosome recycling factor 3064296..3064850 Spirochaeta smaragdinae DSM 11293 9490981 YP_003804564.1 CDS Spirs_2867 NC_014364.1 3064850 3065566 D COGs: COG0020 undecaprenyl pyrophosphate synthase; InterPro IPR001441:IPR018520; KEGG: tit:Thit_1198 undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: uncharacterized protein; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; undecaprenyl diphosphate synthase 3064850..3065566 Spirochaeta smaragdinae DSM 11293 9490982 YP_003804565.1 CDS Spirs_2868 NC_014364.1 3065563 3066402 D COGs: COG4589 CDP-diglyceride synthetase/phosphatidate cytidylyltransferase; InterPro IPR000374; KEGG: btu:BT0119 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: phosphatidate cytidylyltransferase; PFAM: Cytidylyltransferase family; phosphatidate cytidylyltransferase 3065563..3066402 Spirochaeta smaragdinae DSM 11293 9490983 YP_003804566.1 CDS Spirs_2869 NC_014364.1 3066413 3067573 D COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR003821:IPR013512:IPR013644; KEGG: tde:TDE2342 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase domain protein; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 3066413..3067573 Spirochaeta smaragdinae DSM 11293 9490984 YP_003804567.1 CDS Spirs_2870 NC_014364.1 3067573 3068931 D COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR004387:IPR008915:IPR001478; KEGG: tde:TDE2341 membrane-associated zinc metalloprotease PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein; SPTR: membrane-associated zinc metalloprotease ; TIGRFAM: membrane-associated zinc metalloprotease; PFAM: peptidase family M50; PDZ domain (Also known as DHR or GLGF); TIGRFAM: RIP metalloprotease RseP; membrane-associated zinc metalloprotease 3067573..3068931 Spirochaeta smaragdinae DSM 11293 9490985 YP_003804568.1 CDS Spirs_2871 NC_014364.1 3068938 3069552 D KEGG: tde:TDE2183 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3068938..3069552 Spirochaeta smaragdinae DSM 11293 9490986 YP_003804569.1 CDS Spirs_2872 NC_014364.1 3069549 3071558 D InterProIPR019781:IPR019782:IPR017986:IPR001680:IPR 019775; KEGG: tde:TDE2184 hypothetical protein; PFAM: WD40 repeat, subgroup; SMART: hypothetical protein; SPTR: uncharacterized protein; PFAM: WD domain, G-beta repeat; WD40 repeat, subgroup 3069549..3071558 Spirochaeta smaragdinae DSM 11293 9490987 YP_003804570.1 CDS Spirs_2873 NC_014364.1 3071700 3071996 R InterPro IPR019657; KEGG: hor:Hore_19130 hypothetical protein; PFAM: late competence development protein ComFB; SPTR: uncharacterized protein; PFAM: late competence development protein ComFB; late competence development protein ComFB complement(3071700..3071996) Spirochaeta smaragdinae DSM 11293 9490988 YP_003804571.1 CDS Spirs_2874 NC_014364.1 3072027 3073361 R COGs: COG0305 Replicative DNA helicase; InterPro IPR007692:IPR007693:IPR007694; KEGG: tde:TDE1662 replicative DNA helicase; PFAM: DnaB domain protein helicase; SPTR: Replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase; replicative DNA helicase complement(3072027..3073361) Spirochaeta smaragdinae DSM 11293 9490989 YP_003804572.1 CDS Spirs_2875 NC_014364.1 3073358 3073957 R COGs: COG0359 ribosomal protein L9; InterPro IPR020594:IPR020070:IPR020069; KEGG: tde:TDE1675 50S ribosomal protein L9; PFAM: ribosomal protein L9-like; SPTR: ribosomal protein L9; TIGRFAM: ribosomal protein L9; PFAM: ribosomal protein L9, N-terminal domain; ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9; 50S ribosomal protein L9 complement(3073358..3073957) Spirochaeta smaragdinae DSM 11293 9490990 YP_003804573.1 CDS Spirs_2876 NC_014364.1 3073973 3074950 R KEGG: gme:Gmet_2842 hypothetical protein; SPTR: membrane protein, ; PFAM: Predicted membrane protein (DUF2232); hypothetical protein complement(3073973..3074950) Spirochaeta smaragdinae DSM 11293 9490991 YP_003804574.1 CDS Spirs_2877 NC_014364.1 3074961 3075272 R COGs: COG0238 ribosomal protein S18; InterPro IPR001648; KEGG: tpp:TPASS_0061 30S ribosomal protein S18; PFAM: ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: ribosomal protein S18; PFAM: ribosomal protein S18; TIGRFAM: ribosomal protein S18; 30S ribosomal protein S18 complement(3074961..3075272) Spirochaeta smaragdinae DSM 11293 9490992 YP_003804575.1 CDS Spirs_2878 NC_014364.1 3075299 3075733 R COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR011344:IPR000424; KEGG: tde:TDE1677 single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein complement(3075299..3075733) Spirochaeta smaragdinae DSM 11293 9490993 YP_003804576.1 CDS Spirs_2879 NC_014364.1 3075743 3076024 R COGs: COG0360 ribosomal protein S6; InterPro IPR000529:IPR020814; KEGG: tde:TDE1678 30S ribosomal protein S6; PFAM: ribosomal protein S6, bacterial-like; SPTR: 30S ribosomal protein S6; TIGRFAM: ribosomal protein S6; PFAM: ribosomal protein S6; TIGRFAM: ribosomal protein S6; 30S ribosomal protein S6 complement(3075743..3076024) Spirochaeta smaragdinae DSM 11293 9490994 YP_003804577.1 CDS Spirs_2880 NC_014364.1 3076144 3076596 D KEGG: tpp:TPASS_0064 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3076144..3076596 Spirochaeta smaragdinae DSM 11293 9490995 YP_003804578.1 CDS Spirs_2881 NC_014364.1 3076609 3078165 D COGs: COG4284 UDP-glucose pyrophosphorylase; KEGG: bhr:BH0003 hypothetical protein; SPTR: uncharacterized protein; PFAM: UTP--glucose-1-phosphate uridylyltransferase; hypothetical protein 3076609..3078165 Spirochaeta smaragdinae DSM 11293 9490996 YP_003804579.1 CDS Spirs_2882 NC_014364.1 3078174 3078548 D COGs: COG0139 phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496; KEGG: dap:Dacet_0283 phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; PRIAM: phosphoribosyl-AMP cyclohydrolase; SPTR: phosphoribosyl-AMP cyclohydrolase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-AMP cyclohydrolase 3078174..3078548 Spirochaeta smaragdinae DSM 11293 9490997 YP_003804580.1 CDS Spirs_2883 NC_014364.1 3078783 3078953 R InterPro IPR001450:IPR000813:IPR017896:IPR017900; KEGG: ddf:DEFDS_2170 4Fe-4S ferredoxin; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin; PFAM: 4Fe-4S binding domain; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(3078783..3078953) Spirochaeta smaragdinae DSM 11293 9490998 YP_003804581.1 CDS Spirs_2884 NC_014364.1 3079030 3080991 R COGs: COG1154 deoxyxylulose-5-phosphate synthase; InterProIPR005477:IPR005475:IPR005476:IPR005474:IPR 006093; KEGG: tde:TDE1910 1-deoxy-D-xylulose-5-phosphate synthase; PFAM: transketolase central region; transketolase; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: deoxyxylulose-5-phosphate synthase; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase; deoxyxylulose-5-phosphate synthase complement(3079030..3080991) Spirochaeta smaragdinae DSM 11293 9490999 YP_003804582.1 CDS Spirs_2885 NC_014364.1 3081026 3081769 R InterPro IPR000527; KEGG: cjd:JJD26997_1320 flagellar basal body L-ring protein; PFAM: flagellar L-ring protein; SPTR: flagellar L-ring protein FlgH; PFAM: flagellar L-ring protein; flagellar L-ring protein complement(3081026..3081769) Spirochaeta smaragdinae DSM 11293 9491000 YP_003804583.1 CDS Spirs_2886 NC_014364.1 3081979 3082941 D KEGG: nve:NEMVE_v1g88731 hypothetical protein; SPTR: Predicted protein; hypothetical protein 3081979..3082941 Spirochaeta smaragdinae DSM 11293 9491001 YP_003804584.1 CDS Spirs_2887 NC_014364.1 3082925 3084304 D COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR005762:IPR013221:IPR004101; KEGG: tde:TDE0370 UDP-N-acetylmuramoylalanine--D-glutamate ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine/D-glutamate ligase; PFAM: Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase; UDP-N-acetylmuramoylalanine/D-glutamate ligase 3082925..3084304 Spirochaeta smaragdinae DSM 11293 9491002 YP_003804585.1 CDS Spirs_2888 NC_014364.1 3084321 3085355 R COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: phe:Phep_0801 methicillin resistance protein; PFAM: methicillin resistance protein; SPTR: FemAB family protein; PFAM: FemAB family; methicillin resistance protein complement(3084321..3085355) Spirochaeta smaragdinae DSM 11293 9491003 YP_003804586.1 CDS Spirs_2889 NC_014364.1 3085361 3087571 R COGs: COG0143 Methionyl-tRNA synthetase; InterProIPR002304:IPR004495:IPR015413:IPR002547:IPR 014758:IPR001412; KEGG: tde:TDE1063 methionyl-tRNA synthetase; PFAM: tRNA synthetase class I (M); t-RNA-binding domain protein; PRIAM: methionine--tRNA ligase; SPTR: Methionyl-tRNA synthetase; TIGRFAM: methionyl-tRNA synthetase; methionyl-tRNA synthetase subunit beta; PFAM: tRNA synthetases class I (M); tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase; methionyl-tRNA synthetase complement(3085361..3087571) Spirochaeta smaragdinae DSM 11293 9491004 YP_003804587.1 CDS Spirs_2890 NC_014364.1 3087714 3088697 D COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR010201:IPR001107; KEGG: tde:TDE1332 HflK protein, PFAM: band 7 protein; SMART: band 7 protein; SPTR: HflK protein, ; TIGRFAM: HflK protein; PFAM: SPFH domain / Band 7 family; TIGRFAM: HflK protein; HflK protein 3087714..3088697 Spirochaeta smaragdinae DSM 11293 9491005 YP_003804588.1 CDS Spirs_2891 NC_014364.1 3088694 3089692 D COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR010200:IPR001107; KEGG: tde:TDE1333 HflC protein, PFAM: band 7 protein; SMART: band 7 protein; SPTR: HflC protein; TIGRFAM: HflC protein; PFAM: SPFH domain / Band 7 family; TIGRFAM: HflC protein; HflC protein 3088694..3089692 Spirochaeta smaragdinae DSM 11293 9491006 YP_003804589.1 CDS Spirs_2892 NC_014364.1 3089777 3091432 R COGs: COG3392 adenine-specific DNA methylase; InterPro IPR012327:IPR002294:IPR002052; KEGG: bhy:BHWA1_00325 site-specific DNA-methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: adenine-specific DNA methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; adenine-specific DNA-methyltransferase complement(3089777..3091432) Spirochaeta smaragdinae DSM 11293 9491007 YP_003804590.1 CDS Spirs_2893 NC_014364.1 3091484 3092998 D COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR005761:IPR000713:IPR013221:IPR004101; KEGG: btu:BT0201 UDP-N-acetylmuramoylalanyl-D-glutamate--L-ornithine ligase; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; SPTR:UDP-N-acetylmuramoylalanyl-D-glutamate--L-orni thineligase; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramyl-tripeptide synthetases; UDP-N-acetylmuramyl-tripeptide synthetase 3091484..3092998 Spirochaeta smaragdinae DSM 11293 9491008 YP_003804591.1 CDS Spirs_2894 NC_014364.1 3093004 3094083 R COGs: COG0628 permease; InterPro IPR002549; KEGG: pmo:Pmob_0546 hypothetical protein; PFAM: protein of unknown function UPF0118; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF20; hypothetical protein complement(3093004..3094083) Spirochaeta smaragdinae DSM 11293 9491009 YP_003804592.1 CDS Spirs_2895 NC_014364.1 3094156 3095247 D COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterProIPR005905:IPR011127:IPR011095:IPR011761:IPR 000291; KEGG: tde:TDE2385 D-alanyl-alanine synthetase A; PFAM: D-alanine--D-alanine ligase domain protein; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine/D-alanine ligase; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase; D-alanine/D-alanine ligase 3094156..3095247 Spirochaeta smaragdinae DSM 11293 9491010 YP_003804593.1 CDS Spirs_2896 NC_014364.1 3095232 3095741 R COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: mtp:Mthe_1448 nitroreductase; PFAM: nitroreductase; SPTR: nitroreductase; PFAM: nitroreductase family; nitroreductase complement(3095232..3095741) Spirochaeta smaragdinae DSM 11293 9491011 YP_003804594.1 CDS Spirs_2897 NC_014364.1 3095797 3097986 D KEGG: tde:TDE0962 hypothetical protein; SPTR: membrane protein; hypothetical protein 3095797..3097986 Spirochaeta smaragdinae DSM 11293 9491012 YP_003804595.1 CDS Spirs_2898 NC_014364.1 3097983 3099185 D COGs: COG0389 nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126:IPR017963; KEGG: tde:TDE0963 DNA polymerase IV; PFAM: UMUC domain protein DNA-repair protein; PRIAM: DNA-directed DNA polymerase; SPTR: DNA polymerase IV; PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family; DNA-directed DNA polymerase 3097983..3099185 Spirochaeta smaragdinae DSM 11293 9491013 YP_003804596.1 CDS Spirs_2899 NC_014364.1 3099127 3100401 R COGs: COG3391 conserved hypothetical protein; KEGG: tde:TDE1227 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: 40-residue YVTN family beta-propeller repeat; hypothetical protein complement(3099127..3100401) Spirochaeta smaragdinae DSM 11293 9491014 YP_003804597.1 CDS Spirs_2900 NC_014364.1 3100446 3100964 D COGs: COG0791 cell wall-associated hydrolase (invasion-associated protein); InterPro IPR000064; KEGG: pgn:PGN_0754 hypothetical protein; PFAM: NLP/P60 protein; SPTR: NLP/P60 family protein; PFAM: NlpC/P60 family; NLP/P60 protein 3100446..3100964 Spirochaeta smaragdinae DSM 11293 9491015 YP_003804598.1 CDS Spirs_2901 NC_014364.1 3100986 3101444 R KEGG: tpp:TPASS_0552 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3100986..3101444) Spirochaeta smaragdinae DSM 11293 9491016 YP_003804599.1 CDS Spirs_2902 NC_014364.1 3101515 3102006 D COGs: COG0219 rRNA methylase (SpoU class); InterPro IPR001537:IPR016914; KEGG: hor:Hore_11010 RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); SPTR: RNA methyltransferase, TrmH family; PFAM: SpoU rRNA methylase family; TIGRFAM: rRNA methylase, , group 2; tRNA/rRNA methyltransferase SpoU 3101515..3102006 Spirochaeta smaragdinae DSM 11293 9491017 YP_003804600.1 CDS Spirs_2903 NC_014364.1 3102063 3102875 D COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR000304:IPR004455; KEGG: cyt:cce_2615 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase; pyrroline-5-carboxylate reductase 3102063..3102875 Spirochaeta smaragdinae DSM 11293 9491018 YP_003804601.1 CDS Spirs_2904 NC_014364.1 3102877 3104181 D COGs: COG0172 Seryl-tRNA synthetase; InterProIPR002317:IPR015866:IPR002314:IPR018156:IPR 006195; KEGG: tde:TDE2307 seryl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Seryl-tRNA synthetase, class IIa-like; SPTR: Seryl-tRNA synthetase; TIGRFAM: seryl-tRNA synthetase; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase; seryl-tRNA synthetase 3102877..3104181 Spirochaeta smaragdinae DSM 11293 9491019 YP_003804602.1 CDS Spirs_2905 NC_014364.1 3104694 3104906 R KEGG: tpp:TPASS_0777 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3104694..3104906) Spirochaeta smaragdinae DSM 11293 9491020 YP_003804603.1 CDS Spirs_2906 NC_014364.1 3105044 3106489 D COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR006405:IPR015977:IPR007229; KEGG: tde:TDE0174 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: nicotinate phosphoribosyltransferase; nicotinate phosphoribosyltransferase 3105044..3106489 Spirochaeta smaragdinae DSM 11293 9491021 YP_003804604.1 CDS Spirs_2907 NC_014364.1 3106465 3107604 D COGs: COG2089 Sialic acid synthase; InterPro IPR013132:IPR013974:IPR006190; KEGG: tde:TDE0960 NeuB family protein; PFAM: N-acetylneuraminic acid synthase domain; SAF domain protein; SPTR: NeuB family protein; PFAM: NeuB family; N-acetylneuraminic acid synthase domain-containing protein 3106465..3107604 Spirochaeta smaragdinae DSM 11293 9491022 YP_003804605.1 CDS Spirs_2908 NC_014364.1 3107549 3107947 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: dal:Dalk_2353 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3107549..3107947) Spirochaeta smaragdinae DSM 11293 9491023 YP_003804606.1 CDS Spirs_2909 NC_014364.1 3107950 3108417 R KEGG: pca:Pcar_1204 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3107950..3108417) Spirochaeta smaragdinae DSM 11293 9491024 YP_003804607.1 CDS Spirs_2910 NC_014364.1 3108420 3108791 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dal:Dalk_3920 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3108420..3108791) Spirochaeta smaragdinae DSM 11293 9491025 YP_003804608.1 CDS Spirs_2911 NC_014364.1 3108819 3109295 R COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; InterPro IPR005659; KEGG: pca:Pcar_1201 CheD-like chemotaxis protein; PFAM: CheD family protein; SPTR: CheD, stimulates methylation of MCP proteins; PFAM: CheD; stimulates methylation of MCP proteins; chemotaxis protein CheD complement(3108819..3109295) Spirochaeta smaragdinae DSM 11293 9491026 YP_003804609.1 CDS Spirs_2912 NC_014364.1 3109292 3110350 R COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR001789:IPR000673:IPR008248; KEGG: pca:Pcar_1200 chemotactic response regulator/methylesterase; PFAM: CheB methylesterase; response regulator receiver; PRIAM: protein-glutamate methylesterase; SMART: response regulator receiver; SPTR: Response regulator receiver modulated CheB methylesterase; PFAM: CheB methylesterase; Response regulator receiver domain; response regulator receiver modulated CheB methylesterase complement(3109292..3110350) Spirochaeta smaragdinae DSM 11293 9491027 YP_003804610.1 CDS Spirs_2913 NC_014364.1 3110350 3111189 R COGs: COG1352 methylase of chemotaxis methyl-accepting protein; InterPro IPR000780; KEGG: pca:Pcar_1199 methylase of chemotaxis methyl-accepting protein, CheR-like; PFAM: MCP methyltransferase CheR-type; PRIAM: protein-glutamate O-methyltransferase; SMART: MCP methyltransferase CheR-type; SPTR: MCP methyltransferase, CheR-type; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain; CheR-type MCP methyltransferase complement(3110350..3111189) Spirochaeta smaragdinae DSM 11293 9491028 YP_003804611.1 CDS Spirs_2914 NC_014364.1 3111202 3113775 R COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR004105:IPR003594:IPR002545:IPR 004358:IPR005467; KEGG: dal:Dalk_3929 chemotaxis protein CheA; PFAM: ATP-binding region ATPase domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; CheW domain protein; SMART: ATP-binding region ATPase domain protein; Hpt domain protein; CheW domain protein; SPTR: chemotaxis protein CheAs; PFAM: CheW-like domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; chemotaxis protein CheA complement(3111202..3113775) Spirochaeta smaragdinae DSM 11293 9491029 YP_003804612.1 CDS Spirs_2915 NC_014364.1 3113782 3114159 R COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: cvi:CV_1016 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Chemotaxis protein CheY; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3113782..3114159) Spirochaeta smaragdinae DSM 11293 9491030 YP_003804613.1 CDS Spirs_2916 NC_014364.1 3114167 3115420 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090; KEGG: fno:Fnod_1300 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(3114167..3115420) Spirochaeta smaragdinae DSM 11293 9491031 YP_003804614.1 CDS Spirs_2917 NC_014364.1 3115522 3115917 R InterPro IPR002645; KEGG: taf:THA_1827 anti-sigma factor antagonist; PFAM: sulfate transporter/antisigma-factor antagonist STAS; SPTR: anti-sigma factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma-factor antagonist complement(3115522..3115917) Spirochaeta smaragdinae DSM 11293 9491032 YP_003804615.1 CDS Spirs_2918 NC_014364.1 3115883 3117178 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR006675:IPR001789:IPR006674; KEGG: dar:Daro_0970 response regulator receiver; PFAM: response regulator receiver; metal-dependent phosphohydrolase HD sub domain; SMART: response regulator receiver; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; Response regulator receiver domain; response regulator receiver modulated metal dependent phosphohydrolase complement(3115883..3117178) Spirochaeta smaragdinae DSM 11293 9491033 YP_003804616.1 CDS Spirs_2919 NC_014364.1 3117360 3117794 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: tde:TDE1494 chemotaxis protein CheY; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: CheY; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3117360..3117794) Spirochaeta smaragdinae DSM 11293 9491035 YP_003804617.1 CDS Spirs_2920 NC_014364.1 3117809 3118273 R COGs: COG1406 inhibitor of MCP methylation homolog of CheC; InterPro IPR007597; KEGG: tde:TDE1493 chemotaxis protein CheX; PFAM: chemotaxis protein CheC; SPTR: CheX; PFAM: CheC-like family; chemotaxis protein CheC complement(3117809..3118273) Spirochaeta smaragdinae DSM 11293 9491036 YP_003804618.1 CDS Spirs_2921 NC_014364.1 3118288 3119625 R COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545:IPR000780; KEGG: tpp:TPASS_0364 purine-binding chemotaxis protein; PFAM: MCP methyltransferase CheR-type; CheW domain protein; SMART: CheW domain protein; MCP methyltransferase CheR-type; SPTR: Chemotaxis protein CheW; PFAM: CheW-like domain; CheR methyltransferase, SAM binding domain; CheR-type MCP methyltransferase complement(3118288..3119625) Spirochaeta smaragdinae DSM 11293 9491037 YP_003804619.1 CDS Spirs_2922 NC_014364.1 3119648 3122017 R COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR010808:IPR004105:IPR003594:IPR 002545:IPR004358:IPR005467; KEGG: tde:TDE1491 chemotaxis protein CheA; PFAM: CheW domain protein; ATP-binding region ATPase domain protein; P2 response regulator binding domain protein; Hpt domain protein; Signal transducing histidine kinase homodimeric; SMART: CheW domain protein; Hpt domain protein; ATP-binding region ATPase domain protein; SPTR: P2 response regulator binding domain protein; PFAM: P2 response regulator binding domain; CheW-like domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain; chemotaxis protein CheA complement(3119648..3122017) Spirochaeta smaragdinae DSM 11293 9491038 YP_003804620.1 CDS Spirs_2923 NC_014364.1 3122161 3123348 D KEGG: hdu:HD0283 fimbrial outer membrane usher protein; SPTR: Probable fimbrial outer membrane usher protein; hypothetical protein 3122161..3123348 Spirochaeta smaragdinae DSM 11293 9491039 YP_003804621.1 CDS Spirs_2924 NC_014364.1 3123348 3124229 D KEGG: tde:TDE1489 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3123348..3124229 Spirochaeta smaragdinae DSM 11293 9491040 YP_003804622.1 CDS Spirs_2925 NC_014364.1 3124338 3124835 R KEGG: pfh:PFHG_04279 hypothetical protein; SPTR: Ubiquitin-like protease 1 homolog, Ulp1 homolog; hypothetical protein complement(3124338..3124835) Spirochaeta smaragdinae DSM 11293 9491041 YP_003804623.1 CDS Spirs_2926 NC_014364.1 3125233 3126249 R InterPro IPR006714; KEGG: tde:TDE1712 flagellar filament outer layer protein; PFAM: flagellar filament outer layer protein FlaA; SPTR: FLAA=FLAGELLAR filament outer layer polypeptide; PFAM: flagellar filament outer layer protein Flaa; flagellar filament outer layer protein FlaA complement(3125233..3126249) Spirochaeta smaragdinae DSM 11293 9491042 YP_003804624.1 CDS Spirs_2927 NC_014364.1 3126336 3126830 R InterPro IPR019606; KEGG: gur:Gura_0488 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: uncharacterized protein; PFAM: sporulation and spore germination; Lipoprotein LpqB, GerMN domain-containing protein complement(3126336..3126830) Spirochaeta smaragdinae DSM 11293 9491043 YP_003804625.1 CDS Spirs_2928 NC_014364.1 3126846 3127853 R COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: tpp:TPASS_0247 N-acetylmuramoyl-L-alanine amidase; PFAM: cell wall hydrolase/autolysin; SMART: cell wall hydrolase/autolysin; SPTR: N-acetylmuramoyl-L-alanine amidase, family 3; PFAM: N-acetylmuramoyl-L-alanine amidase; cell wall hydrolase/autolysin complement(3126846..3127853) Spirochaeta smaragdinae DSM 11293 9491044 YP_003804626.1 CDS Spirs_2929 NC_014364.1 3127838 3129505 R COGs: COG0439 Biotin carboxylase; InterPro IPR003135:IPR011761; KEGG: tde:TDE2209 CarB family protein; PFAM: ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; SPTR: CarB family protein; PFAM: ATP-grasp domain; ATP-dependent carboxylate-amine ligase domain-containing protein ATP-grasp complement(3127838..3129505) Spirochaeta smaragdinae DSM 11293 9491045 YP_003804627.1 CDS Spirs_2930 NC_014364.1 3129489 3131345 R COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013217; KEGG: tde:TDE1917 cytidyltransferase-like protein; PFAM: methyltransferase type 12; SPTR: Cytidylyltransferase domain protein; PFAM: methyltransferase domain; type 12 methyltransferase complement(3129489..3131345) Spirochaeta smaragdinae DSM 11293 9491046 YP_003804628.1 CDS Spirs_2931 NC_014364.1 3131338 3132045 R COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: tpp:TPASS_0288 spore coat polysaccharide biosynthesis protein F; PFAM: acylneuraminate cytidylyltransferase; SPTR: Spore coat polysaccharide biosynthesis protein (SpsF); PFAM: Cytidylyltransferase; acylneuraminate cytidylyltransferase complement(3131338..3132045) Spirochaeta smaragdinae DSM 11293 9491047 YP_003804629.1 CDS Spirs_2932 NC_014364.1 3132042 3133001 R KEGG: tde:TDE1918 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3132042..3133001) Spirochaeta smaragdinae DSM 11293 9491048 YP_003804630.1 CDS Spirs_2933 NC_014364.1 3132976 3134598 R COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: tde:TDE1919 hypothetical protein; PFAM: radical SAM domain protein; SPTR: Conserved domain protein; PFAM: radical SAM superfamily; radical SAM protein complement(3132976..3134598) Spirochaeta smaragdinae DSM 11293 9491049 YP_003804631.1 CDS Spirs_2934 NC_014364.1 3134598 3135698 R COGs: COG0263 glutamate 5-kinase; InterProIPR005715:IPR001048:IPR002478:IPR001057:IPR 011529:IPR019797; KEGG: adg:Adeg_0186 glutamate 5-kinase; PFAM: aspartate/glutamate/uridylate kinase; PUA domain containing protein; SMART: PUA domain containing protein; SPTR: glutamate 5-kinase; TIGRFAM: glutamate 5-kinase; PFAM: PUA domain; Amino acid kinase family; TIGRFAM: glutamate 5-kinase; glutamate 5-kinase complement(3134598..3135698) Spirochaeta smaragdinae DSM 11293 9491050 YP_003804632.1 CDS Spirs_2935 NC_014364.1 3135708 3137012 R COGs: COG0014 gamma-glutamyl phosphate reductase; InterPro IPR000965:IPR015590:IPR012134:IPR020593; KEGG: pth:PTH_2594 gamma-glutamyl phosphate reductase; PFAM: aldehyde dehydrogenase; PRIAM: glutamate-5-semialdehyde dehydrogenase; SPTR: gamma-glutamyl phosphate reductase; TIGRFAM: gamma-glutamyl phosphate reductase; PFAM: aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase; gamma-glutamyl phosphate reductase complement(3135708..3137012) Spirochaeta smaragdinae DSM 11293 9491051 YP_003804633.1 CDS Spirs_2936 NC_014364.1 3137067 3138614 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: tye:THEYE_A0181 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3137067..3138614) Spirochaeta smaragdinae DSM 11293 9491052 YP_003804634.1 CDS Spirs_2937 NC_014364.1 3138719 3139504 D InterPro IPR017587; KEGG: gme:Gmet_2139 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: probable selenium-dependent hydroxylase accessory protein YqeC; hypothetical protein 3138719..3139504 Spirochaeta smaragdinae DSM 11293 9491053 YP_003804635.1 CDS Spirs_2938 NC_014364.1 3139749 3141377 D COGs: COG1975 xanthine and CO dehydrogenase maturation factor XdhC/CoxF family; InterPro IPR017695:IPR003777; KEGG: aha:AHA_2167 xanthine dehydrogenase accessory factor; PFAM: protein of unknown function DUF182; SPTR: xanthine dehydrogenase accessory factor, subfamily, ; TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; PFAM: Pyridine nucleotide-disulphide oxidoreductase; XdhC and CoxI family; TIGRFAM: selenium-dependent molybdenum hydroxylase system protein, YqeB family; selenium-dependent molybdenum hydroxylase system protein, YqeB family 3139749..3141377 Spirochaeta smaragdinae DSM 11293 9491054 YP_003804636.1 CDS Spirs_2939 NC_014364.1 3141374 3142414 D COGs: COG0709 Selenophosphate synthase; InterPro IPR004536:IPR000728:IPR010918; KEGG: ppd:Ppro_1707 selenide, water dikinase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; SPTR: Selenide, water dikinase; TIGRFAM: selenide, water dikinase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: selenium donor protein; selenide, water dikinase 3141374..3142414 Spirochaeta smaragdinae DSM 11293 9491055 YP_003804637.1 CDS Spirs_2940 NC_014364.1 3142425 3143066 D InterPro IPR019870:IPR001455; KEGG: pth:PTH_1504 redox protein; PFAM: SirA family protein; SPTR: Predicted redox protein; TIGRFAM: selenium metabolism protein YedF; PFAM: DsrE/DsrF-like family; SirA-like protein; TIGRFAM: selenium metabolism protein YedF; selenium metabolism protein YedF 3142425..3143066 Spirochaeta smaragdinae DSM 11293 9491056 YP_003804638.1 CDS Spirs_2941 NC_014364.1 3143088 3144179 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: ton:TON_0296 ABC-type iron(III)-siderophore transporter, periplasmic component; PFAM: periplasmic binding protein; SPTR: ABC-type iron(III)-siderophore transport system, periplasmic component fused to N-terminal uncharacterized domain; PFAM: Periplasmic binding protein; periplasmic binding protein 3143088..3144179 Spirochaeta smaragdinae DSM 11293 9491057 YP_003804639.1 CDS Spirs_2942 NC_014364.1 3144226 3145194 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: mem:Memar_0028 transporter permease; PFAM: transporter permease; SPTR: transport system permease; PFAM: FecCD transport family; transporter permease 3144226..3145194 Spirochaeta smaragdinae DSM 11293 9491058 YP_003804640.1 CDS Spirs_2943 NC_014364.1 3145196 3145966 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR003439:IPR003593; KEGG: dsy:DSY0366 hypothetical protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 3145196..3145966 Spirochaeta smaragdinae DSM 11293 9491059 YP_003804641.1 CDS Spirs_2944 NC_014364.1 3145975 3147705 R COGs: COG1001 adenine deaminase; InterPro IPR006679:IPR006680; KEGG: aoe:Clos_0379 adenine deaminase; PFAM: amidohydrolase; PRIAM: adenine deaminase; SPTR: adenine deaminase; TIGRFAM: adenine deaminase; PFAM: Amidohydrolase family; TIGRFAM: adenine deaminase; adenine deaminase complement(3145975..3147705) Spirochaeta smaragdinae DSM 11293 9491060 YP_003804642.1 CDS Spirs_2945 NC_014364.1 3147769 3149421 D COGs: COG3653 N-acyl-D-aspartate/D-glutamate deacylase; InterPro IPR006680; KEGG: ppr:PBPRB0017 deacylase; PFAM: amidohydrolase; PRIAM: N-acyl-D-aspartate deacylase; SPTR: Hypothetical deacylase; PFAM: D-aminoacylase, C-terminal region; Amidohydrolase family; N-acyl-D-aspartate deacylase 3147769..3149421 Spirochaeta smaragdinae DSM 11293 9491061 YP_003804643.1 CDS Spirs_2946 NC_014364.1 3149488 3150771 D COGs: COG2252 Permease; InterPro IPR006043; KEGG: amt:Amet_4573 xanthine/uracil/vitamin C permease; PFAM: xanthine/uracil/vitamin C permease; SPTR: xanthine/uracil/vitamin C permease; PFAM: Permease family; xanthine/uracil/vitamin C permease 3149488..3150771 Spirochaeta smaragdinae DSM 11293 9491062 YP_003804644.1 CDS Spirs_2947 NC_014364.1 3151041 3151478 D COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: dds:Ddes_1077 Rrf2 family/BadM/Rrf2 family transcriptional regulator/Rrf2 family; PFAM: protein of unknown function UPF0074; SPTR: transcriptional regulator, BadM/Rrf2 family; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator); BadM/Rrf2 family transcriptional regulator 3151041..3151478 Spirochaeta smaragdinae DSM 11293 9491063 YP_003804645.1 CDS Spirs_2948 NC_014364.1 3151545 3152486 D COGs: COG1897 homoserine trans-succinylase; InterPro IPR005697; KEGG: tna:CTN_1695 homoserine O-succinyltransferase; PFAM: homoserine O-succinyltransferase; PRIAM: homoserine O-succinyltransferase; SPTR: uncharacterized protein; TIGRFAM: homoserine O-succinyltransferase; PFAM: homoserine O-succinyltransferase; TIGRFAM: homoserine O-succinyltransferase; homoserine O-succinyltransferase 3151545..3152486 Spirochaeta smaragdinae DSM 11293 9491064 YP_003804646.1 CDS Spirs_2949 NC_014364.1 3152483 3153763 D COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: dba:Dbac_2132 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: cysteine synthase; SPTR: O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; O-acetylhomoserine/O-acetylserine sulfhydrylase 3152483..3153763 Spirochaeta smaragdinae DSM 11293 9491065 YP_003804647.1 CDS Spirs_2950 NC_014364.1 3153765 3154700 D COGs: COG0031 cysteine synthase; InterPro IPR005856:IPR005859:IPR001926; KEGG: dba:Dbac_1638 cysteine synthase A; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases; cysteine synthase A 3153765..3154700 Spirochaeta smaragdinae DSM 11293 9491066 YP_003804648.1 CDS Spirs_2951 NC_014364.1 3154731 3155222 R COGs: COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS/CutS homologs; InterPro IPR001041:IPR002888:IPR006058; KEGG: pth:PTH_1579 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; PFAM: [2Fe-2S]-binding domain protein; ferredoxin; SPTR: dehydrogenase, 2Fe-2S ferredoxin-like subunit, small chain; PFAM: 2Fe-2S iron-sulfur cluster binding domain; [2Fe-2S] binding domain; (2Fe-2S)-binding domain-containing protein complement(3154731..3155222) Spirochaeta smaragdinae DSM 11293 9491067 YP_003804649.1 CDS Spirs_2952 NC_014364.1 3155219 3157486 R COGs: COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL/CutL homologs; InterPro IPR000674:IPR008274; KEGG: pmo:Pmob_1732 xanthine dehydrogenase; PFAM: aldehyde oxidase and xanthine dehydrogenase molybdopterin binding; aldehyde oxidase and xanthine dehydrogenase a/b hammerhead; SPTR: dehydrogenase, molybdenum binding subunit, large chain; PFAM: Molybdopterin-binding domain of aldehyde dehydrogenase; aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; molybdopterin binding aldehyde oxidase and xanthine dehydrogenase protein complement(3155219..3157486) Spirochaeta smaragdinae DSM 11293 9491068 YP_003804650.1 CDS Spirs_2953 NC_014364.1 3157789 3159216 D COGs: COG2233 xanthine/uracil permease; InterPro IPR006042:IPR017588:IPR006043; KEGG: pmy:Pmen_3698 uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; SPTR: xanthine permease subfamily; TIGRFAM: xanthine permease; uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease; xanthine permease; xanthine permease 3157789..3159216 Spirochaeta smaragdinae DSM 11293 9491069 YP_003804651.1 CDS Spirs_2954 NC_014364.1 3159463 3161055 D COGs: COG0038 chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: drm:Dred_2944 Cl-channel, voltage-gated family protein; PFAM: Cl- channel voltage-gated family protein; TrkA-C domain protein; SPTR: Cl-channel, voltage-gated family protein; PFAM: Voltage gated chloride channel; TrkA-C domain; Cl- channel voltage-gated family protein 3159463..3161055 Spirochaeta smaragdinae DSM 11293 9491070 YP_003804652.1 CDS Spirs_2955 NC_014364.1 3161122 3161706 D COGs: COG2818 3-methyladenine DNA glycosylase; InterPro IPR005019; KEGG: tit:Thit_0082 DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase; PRIAM: DNA-3-methyladenine glycosylase I; SPTR: DNA-3-methyladenine glycosylase I; manually curated; PFAM: methyladenine glycosylase; TIGRFAM: DNA-3-methyladenine glycosylase I; DNA-3-methyladenine glycosylase I 3161122..3161706 Spirochaeta smaragdinae DSM 11293 9491071 YP_003804653.1 CDS Spirs_2956 NC_014364.1 3161723 3162610 R COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: dat:HRM2_37860 DraG2; PFAM: ADP-ribosylation/crystallin J1; SPTR: DraG2; PFAM: ADP-ribosylglycohydrolase; ADP-ribosylation/crystallin J1 complement(3161723..3162610) Spirochaeta smaragdinae DSM 11293 9491072 YP_003804654.1 CDS Spirs_2957 NC_014364.1 3162903 3163655 R COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: drm:Dred_2188 GntR domain-containing protein; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(3162903..3163655) Spirochaeta smaragdinae DSM 11293 9491073 YP_003804655.1 CDS Spirs_2959 NC_014364.1 3164100 3164963 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_20850 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 3164100..3164963 Spirochaeta smaragdinae DSM 11293 9491075 YP_003804656.1 CDS Spirs_2960 NC_014364.1 3164993 3166354 D COGs: COG1486 alpha-galactosidase/6-phospho-beta-glucosidase family 4 of glycosyl hydrolase; InterPro IPR001088:IPR019802; KEGG: tau:Tola_2010 glycoside hydrolase family 4; PFAM: glycoside hydrolase family 4; SPTR: glycoside hydrolase family 4; PFAM: Family 4 glycosyl hydrolase; Family 4 glycosyl hydrolase C-terminal domain; glycoside hydrolase family protein 3164993..3166354 Spirochaeta smaragdinae DSM 11293 9491076 YP_003804657.1 CDS Spirs_2961 NC_014364.1 3166609 3167559 D COGs: COG0385 Na+-dependent transporter; InterPro IPR002657; KEGG: bid:Bind_0866 bile acid:sodium symporter; PFAM: Bile acid:sodium symporter; SPTR: Sodium Bile acid symporter family; PFAM: Sodium Bile acid symporter family; sodium symporter 3166609..3167559 Spirochaeta smaragdinae DSM 11293 9491077 YP_003804658.1 CDS Spirs_2962 NC_014364.1 3167634 3168992 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: gme:Gmet_2508 multi anti extrusion protein MatE; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(3167634..3168992) Spirochaeta smaragdinae DSM 11293 9491078 YP_003804659.1 CDS Spirs_2963 NC_014364.1 3169055 3170224 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: bfa:Bfae_04860 argininosuccinate lyase; PFAM: PfkB domain protein; SPTR: Argininosuccinate lyase; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(3169055..3170224) Spirochaeta smaragdinae DSM 11293 9491079 YP_003804660.1 CDS Spirs_2964 NC_014364.1 3170221 3170895 R COGs: COG3822 ABC-type sugar transporter auxiliary component; InterPro IPR010864; KEGG: dde:Dde_2521 hypothetical protein; PFAM: protein of unknown function DUF1498; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1498); hypothetical protein complement(3170221..3170895) Spirochaeta smaragdinae DSM 11293 9491080 YP_003804661.1 CDS Spirs_2965 NC_014364.1 3170986 3171957 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: dfe:Dfer_4121 LacI family transcriptional regulator; SMART: regulatory protein LacI; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 3170986..3171957 Spirochaeta smaragdinae DSM 11293 9491081 YP_003804662.1 CDS Spirs_2966 NC_014364.1 3172010 3173170 R KEGG: smd:Smed_2040 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3172010..3173170) Spirochaeta smaragdinae DSM 11293 9491082 YP_003804663.1 CDS Spirs_2967 NC_014364.1 3173352 3173600 D KEGG: ate:Athe_0168 CopG family transcriptional regulator; SPTR: CopG family transcriptional regulator; CopG family transcriptional regulator 3173352..3173600 Spirochaeta smaragdinae DSM 11293 9491083 YP_003804664.1 CDS Spirs_2968 NC_014364.1 3173607 3174758 D COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR006638:IPR005244; KEGG: lhk:LHK_02331 biotin synthetase; PFAM: radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: biotin synthetase; PFAM: radical SAM superfamily; radical SAM protein 3173607..3174758 Spirochaeta smaragdinae DSM 11293 9491084 YP_003804665.1 CDS Spirs_2969 NC_014364.1 3174843 3176531 D COGs: COG1966 carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: tga:TGAM_0942 carbon starvation protein A (CstA); PFAM: carbon starvation protein CstA; SPTR: carbon starvation protein A (CstA); PFAM: carbon starvation protein CstA; carbon starvation protein CstA 3174843..3176531 Spirochaeta smaragdinae DSM 11293 9491085 YP_003804666.1 CDS Spirs_2970 NC_014364.1 3176626 3176916 D KEGG: dat:HRM2_21750 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3176626..3176916 Spirochaeta smaragdinae DSM 11293 9491086 YP_003804667.1 CDS Spirs_2971 NC_014364.1 3176916 3177845 D COGs: COG0003 ATPase involved in chromosome partitioning; InterPro IPR003348; KEGG: tsi:TSIB_0235 arsenical pump-driving ATPase; PFAM: Anion-transporting ATPase; PRIAM: Arsenite-transporting ATPase; SPTR: Arsenical pump-driving ATPase; PFAM: Anion-transporting ATPase; TIGRFAM: arsenite-activated ATPase (arsA); Arsenite-transporting ATPase 3176916..3177845 Spirochaeta smaragdinae DSM 11293 9491087 YP_003804668.1 CDS Spirs_2972 NC_014364.1 3177842 3178480 D KEGG: tko:TK0996 hypothetical protein; SPTR: Hypothetical membrane protein, conserved; hypothetical protein 3177842..3178480 Spirochaeta smaragdinae DSM 11293 9491088 YP_003804669.1 CDS Spirs_2973 NC_014364.1 3178561 3182946 D COGs: COG1201 Lhr-like helicase; InterProIPR011545:IPR001650:IPR013701:IPR014021:IPR 014001; KEGG: dae:Dtox_2613 DEAD/DEAH box helicase; PFAM: DEAD/DEAH box helicase; helicase; DEAD/H associated domain protein; SMART: DEAD-like helicase ; helicase; SPTR: DEAD/DEAH box helicase; PFAM: Helicase conserved C-terminal domain; DEAD/H associated; DEAD/DEAH box helicase; DEAD/DEAH box helicase 3178561..3182946 Spirochaeta smaragdinae DSM 11293 9491089 YP_003804670.1 CDS Spirs_2974 NC_014364.1 3182958 3184700 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003660:IPR011495:IPR003594:IPR005467; KEGG: dma:DMR_44580 sensor histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; SPTR: sensor histidine kinase; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 3182958..3184700 Spirochaeta smaragdinae DSM 11293 9491090 YP_003804671.1 CDS Spirs_2975 NC_014364.1 3184704 3186413 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR003018:IPR003661:IPR003594:IPR001789:IPR 004358:IPR005467; KEGG: dma:DMR_01670 two-component hybrid sensor and regulator; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; GAF sensor hybrid histidine kinase complement(3184704..3186413) Spirochaeta smaragdinae DSM 11293 9491091 YP_003804672.1 CDS Spirs_2976 NC_014364.1 3186544 3187884 R COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: pth:PTH_0496 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases; PFAM: carboxylyase-related protein; SPTR: uncharacterized protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; UbiD family decarboxylase complement(3186544..3187884) Spirochaeta smaragdinae DSM 11293 9491092 YP_003804673.1 CDS Spirs_2977 NC_014364.1 3187898 3188647 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663:IPR018221; KEGG: cwo:Cwoe_2778 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(3187898..3188647) Spirochaeta smaragdinae DSM 11293 9491093 YP_003804674.1 CDS Spirs_2978 NC_014364.1 3188754 3189482 D COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: hor:Hore_08770 transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; UbiC transcription regulator-associated domain protein; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator 3188754..3189482 Spirochaeta smaragdinae DSM 11293 9491094 YP_003804675.1 CDS Spirs_2979 NC_014364.1 3189424 3190971 R COGs: COG0665 glycine/D-amino acid oxidase (deaminating); InterPro IPR007419:IPR006076; KEGG: acp:A2cp1_1475 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; FAD dependent oxidoreductase complement(3189424..3190971) Spirochaeta smaragdinae DSM 11293 9491095 YP_003804676.1 CDS Spirs_2980 NC_014364.1 3190961 3192448 R COGs: COG0492 thioredoxin reductase; InterPro IPR013027:IPR001450:IPR017896:IPR017900; KEGG: tai:Taci_0971 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(3190961..3192448) Spirochaeta smaragdinae DSM 11293 9491096 YP_003804677.1 CDS Spirs_2981 NC_014364.1 3192432 3192758 R KEGG: abi:Aboo_0089 FAD-dependent pyridine nucleotide-disulfide oxidoreductase; SPTR: uncharacterized protein; FAD-dependent pyridine nucleotide-disulfide oxidoreductase complement(3192432..3192758) Spirochaeta smaragdinae DSM 11293 9491097 YP_003804678.1 CDS Spirs_2982 NC_014364.1 3192820 3193650 R COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: tgr:Tgr7_0569 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel; mechanosensitive ion channel MscS complement(3192820..3193650) Spirochaeta smaragdinae DSM 11293 9491098 YP_003804679.1 CDS Spirs_2983 NC_014364.1 3193652 3194470 R KEGG: tgr:Tgr7_0568 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF432); hypothetical protein complement(3193652..3194470) Spirochaeta smaragdinae DSM 11293 9491099 YP_003804680.1 CDS Spirs_2984 NC_014364.1 3194763 3195074 R COGs: COG3118 thioredoxin domain-containing protein; InterProIPR005746:IPR013766:IPR006662:IPR017936:IPR 017937; KEGG: cte:CT0785 thioredoxin; PFAM: thioredoxin domain; SPTR: thioredoxin-1; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin; thioredoxin complement(3194763..3195074) Spirochaeta smaragdinae DSM 11293 9491100 YP_003804681.1 CDS Spirs_2985 NC_014364.1 3195224 3196234 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: str:Sterm_4014 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: uncharacterized protein; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(3195224..3196234) Spirochaeta smaragdinae DSM 11293 9491101 YP_003804682.1 CDS Spirs_2986 NC_014364.1 3196249 3197139 R COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307:IPR011418; KEGG: clo:HMPREF0868_0019 AP endonuclease, family 2; PFAM: xylose isomerase; AP endonuclease 2 domain protein; PRIAM: myo-inosose-2 dehydratase; SPTR: 2-keto-myo-inositol dehydratase; PFAM: Xylose isomerase-like TIM barrel; myo-inosose-2 dehydratase complement(3196249..3197139) Spirochaeta smaragdinae DSM 11293 9491102 YP_003804683.1 CDS Spirs_2987 NC_014364.1 3197175 3199049 R COGs: COG3962 acetolactate synthase; InterPro IPR012001:IPR012000:IPR011766:IPR000399; KEGG: psb:Psyr_3269 pyruvate decarboxylase:pyruvate decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein TPP binding domain protein; SPTR: pyruvate decarboxylase:pyruvate decarboxylase; PFAM: thiamine pyrophosphate enzyme, central domain; thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; thiamine pyrophosphate protein TPP binding domain-containing protein complement(3197175..3199049) Spirochaeta smaragdinae DSM 11293 9491103 YP_003804684.1 CDS Spirs_2988 NC_014364.1 3199046 3199861 R COGs: COG3718 Uncharacterized protein involved in inositol metabolism; InterPro IPR010669; KEGG: ctc:CTC00509 myo-inositol catabolism protein IolB; PFAM: myo-inositol catabolism IolB domain protein; SPTR: myo-inositol catabolism protein iolB; PFAM: KduI/IolB family; myo-inositol catabolism IolB domain-containing protein complement(3199046..3199861) Spirochaeta smaragdinae DSM 11293 9491104 YP_003804685.1 CDS Spirs_2989 NC_014364.1 3199883 3200908 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tna:CTN_1371 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3199883..3200908) Spirochaeta smaragdinae DSM 11293 9491105 YP_003804686.1 CDS Spirs_2990 NC_014364.1 3200909 3201922 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: str:Sterm_4008 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase domain protein; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(3200909..3201922) Spirochaeta smaragdinae DSM 11293 9491106 YP_003804687.1 CDS Spirs_2991 NC_014364.1 3202282 3203241 R COGs: COG3958 transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: kol:Kole_0992 transketolase; PFAM: transketolase; transketolase; SPTR: transketolase; PFAM: transketolase, C-terminal domain; transketolase, pyrimidine binding domain; transketolase complement(3202282..3203241) Spirochaeta smaragdinae DSM 11293 9491107 YP_003804688.1 CDS Spirs_2992 NC_014364.1 3203238 3204080 R COGs: COG3959 transketolase N-terminal subunit; InterPro IPR005474; KEGG: kol:Kole_0993 transketolase; PFAM: transketolase; SPTR: transketolase; PFAM: transketolase, thiamine diphosphate binding domain; transketolase complement(3203238..3204080) Spirochaeta smaragdinae DSM 11293 9491108 YP_003804689.1 CDS Spirs_2993 NC_014364.1 3204182 3204952 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: cwo:Cwoe_1464 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 3204182..3204952 Spirochaeta smaragdinae DSM 11293 9491109 YP_003804690.1 CDS Spirs_2994 NC_014364.1 3205028 3206362 R COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: cts:Ctha_2724 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein; outer membrane efflux protein complement(3205028..3206362) Spirochaeta smaragdinae DSM 11293 9491110 YP_003804691.1 CDS Spirs_2995 NC_014364.1 3206368 3209484 R COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR005080; KEGG: cts:Ctha_2723 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; acriflavin resistance protein complement(3206368..3209484) Spirochaeta smaragdinae DSM 11293 9491111 YP_003804692.1 CDS Spirs_2996 NC_014364.1 3209495 3210538 R COGs: COG0845 membrane-fusion protein; InterPro IPR006143; KEGG: cts:Ctha_2722 efflux transporter RND family, MFP subunit; SPTR: uncharacterized protein; TIGRFAM: efflux transporter RND family, MFP subunit; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit complement(3209495..3210538) Spirochaeta smaragdinae DSM 11293 9491112 YP_003804693.1 CDS Spirs_2997 NC_014364.1 3210613 3211290 R COGs: COG1309 transcriptional regulator; InterPro IPR001647; KEGG: ara:Arad_7775 transcriptional regulator protein; PFAM: regulatory protein TetR; SPTR: transcriptional regulator protein; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(3210613..3211290) Spirochaeta smaragdinae DSM 11293 9491113 YP_003804694.1 CDS Spirs_2998 NC_014364.1 3211492 3213711 D COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: ppu:PP_4514 patatin; PFAM: patatin; SPTR: uncharacterized protein; PFAM: patatin-like phospholipase; patatin 3211492..3213711 Spirochaeta smaragdinae DSM 11293 9491114 YP_003804695.1 CDS Spirs_2999 NC_014364.1 3213722 3214213 D COGs: COG0350 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048:IPR001497; KEGG: cbe:Cbei_0456 methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; methylated-DNA/protein- cysteinemethyltransferase 3213722..3214213 Spirochaeta smaragdinae DSM 11293 9491115 YP_003804696.1 CDS Spirs_3000 NC_014364.1 3214426 3214734 R KEGG: cch:Cag_1252 ferredoxin 2Fe-2S; SPTR: Ferredoxin, 2Fe-2S; ferredoxin 2Fe-2S complement(3214426..3214734) Spirochaeta smaragdinae DSM 11293 9491116 YP_003804697.1 CDS Spirs_3001 NC_014364.1 3214753 3216018 R COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR003731:IPR006638:IPR000385; KEGG: pph:Ppha_1956 nitrogenase cofactor biosynthesis protein NifB; PFAM: radical SAM protein; dinitrogenase iron-molybdenum cofactor biosynthesis protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: nitrogenase cofactor biosynthesis protein NifB; PFAM: radical SAM superfamily; dinitrogenase iron-molybdenum cofactor; TIGRFAM: nitrogenase cofactor biosynthesis protein NifB; radical SAM protein complement(3214753..3216018) Spirochaeta smaragdinae DSM 11293 9491117 YP_003804698.1 CDS Spirs_3002 NC_014364.1 3216043 3217491 R COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510:IPR000318; KEGG: cpb:Cphamn1_1757 nitrogenase; PFAM: oxidoreductase/nitrogenase component 1; PRIAM: nitrogenase; SPTR: nitrogenase; PFAM: nitrogenase component 1 type oxidoreductase; nitrogenase complement(3216043..3217491) Spirochaeta smaragdinae DSM 11293 9491118 YP_003804699.1 CDS Spirs_3003 NC_014364.1 3217467 3218855 R COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005973:IPR000510:IPR000318; KEGG: cts:Ctha_1030 nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: oxidoreductase/nitrogenase component 1; SPTR: nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: nitrogenase component 1 type oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron cofactor biosynthesis protein NifE; nitrogenase MoFe cofactor biosynthesis protein NifE complement(3217467..3218855) Spirochaeta smaragdinae DSM 11293 9491119 YP_003804700.1 CDS Spirs_3004 NC_014364.1 3218869 3220251 R COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005976:IPR000510:IPR000318; KEGG: cph:Cpha266_0740 nitrogenase molybdenum-iron protein beta chain; PFAM: oxidoreductase/nitrogenase component 1; PRIAM: nitrogenase; SPTR: nitrogenase molybdenum-iron protein beta chain; TIGRFAM: nitrogenase molybdenum-iron protein beta chain; PFAM: nitrogenase component 1 type oxidoreductase; TIGRFAM: nitrogenase molybdenum-iron protein beta chain; nitrogenase molybdenum-iron protein beta chain complement(3218869..3220251) Spirochaeta smaragdinae DSM 11293 9491120 YP_003804701.1 CDS Spirs_3005 NC_014364.1 3220264 3221886 R COGs: COG2710 nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR005972:IPR010143:IPR000510:IPR000318; KEGG: cpb:Cphamn1_1754 nitrogenase molybdenum-iron protein alpha chain; PFAM: oxidoreductase/nitrogenase component 1; PRIAM: nitrogenase; SPTR: nitrogenase protein alpha chain; TIGRFAM: nitrogenase molybdenum-iron protein alpha chain; nitrogenase component I, alpha chain; PFAM: nitrogenase component 1 type oxidoreductase; TIGRFAM: nitrogenase component I, alpha chain; nitrogenase molybdenum-iron protein alpha chain; nitrogenase molybdenum-iron protein alpha chain complement(3220264..3221886) Spirochaeta smaragdinae DSM 11293 9491121 YP_003804702.1 CDS Spirs_3006 NC_014364.1 3221898 3222275 R COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187:IPR017918; KEGG: pvi:Cvib_1345 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; nitrogen regulatory protein P-II complement(3221898..3222275) Spirochaeta smaragdinae DSM 11293 9491122 YP_003804703.1 CDS Spirs_3007 NC_014364.1 3222275 3222601 R COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR002187:IPR017918; KEGG: paa:Paes_1628 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; nitrogen regulatory protein P-II complement(3222275..3222601) Spirochaeta smaragdinae DSM 11293 9491123 YP_003804704.1 CDS Spirs_3008 NC_014364.1 3222612 3223439 R COGs: COG1348 nitrogenase subunit NifH (ATPase); InterPro IPR005977:IPR000392; KEGG: cts:Ctha_1035 nitrogenase reductase; PFAM: NifH/frxC-family protein; PRIAM: nitrogenase; SPTR: nitrogenase iron protein; TIGRFAM: nitrogenase iron protein; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein; nitrogenase iron protein complement(3222612..3223439) Spirochaeta smaragdinae DSM 11293 9491124 YP_003804705.1 CDS Spirs_3009 NC_014364.1 3223744 3225324 R COGs: COG3604 transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains; InterProIPR003018:IPR002078:IPR002197:IPR020441:IPR 003593; KEGG: cts:Ctha_1655 transcriptional regulator, NifA, fis family; PFAM: sigma-54 factor interaction domain-containing protein; GAF domain protein; helix-turn-helix Fis-type; SMART: GAF domain protein; ATPase AAA; SPTR: transcriptional regulator, NifA, Fis Family; PFAM: GAF domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; TIGRFAM: Nif-specific regulatory protein; Fis family transcriptional regulator complement(3223744..3225324) Spirochaeta smaragdinae DSM 11293 9491125 YP_003804706.1 CDS Spirs_3010 NC_014364.1 3225293 3226441 R COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR002034; KEGG: cts:Ctha_1654 homocitrate synthase; PFAM: pyruvate carboxyltransferase; PRIAM: Homocitrate synthase; SPTR: Homocitrate synthase; PFAM: HMGL-like; Homocitrate synthase complement(3225293..3226441) Spirochaeta smaragdinae DSM 11293 9491126 YP_003804707.1 CDS Spirs_3011 NC_014364.1 3226922 3227716 D COGs: COG0725 ABC-type molybdate transporter periplasmic component; InterPro IPR005950:IPR006059; KEGG: eoi:ECO111_0773 molybdate-binding periplasmic protein ModA; PFAM: extracellular solute-binding protein family 1; SPTR: Molybdate-binding periplasmic protein ModA; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein 3226922..3227716 Spirochaeta smaragdinae DSM 11293 9491127 YP_003804708.1 CDS Spirs_3012 NC_014364.1 3227723 3228427 D COGs: COG4149 ABC-type molybdate transporter permease; InterPro IPR011867:IPR000515; KEGG: vfm:VFMJ11_A0328 molybdate ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Molybdate ABC transporter permease; TIGRFAM: molybdate ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: molybdate ABC transporter permease; molybdate ABC transporter inner membrane subunit 3227723..3228427 Spirochaeta smaragdinae DSM 11293 9491128 YP_003804709.1 CDS Spirs_3013 NC_014364.1 3228411 3229466 D COGs: COG4148 ABC-type molybdate transporter ATPase component; InterProIPR011868:IPR003439:IPR005116:IPR003593:IPR 017871; KEGG: mei:Msip34_2324 molybdate ABC transporter ATPase; PFAM: ABC transporter related; TOBE domain protein; SMART: ATPase AAA; SPTR: Molybdate ABC transporter ATPase; TIGRFAM: molybdate ABC transporter ATPase subunit; PFAM: ABC transporter; TOBE domain; TIGRFAM: molybdenum ABC transporter ATP-binding protein; molybdate ABC transporter ATPase 3228411..3229466 Spirochaeta smaragdinae DSM 11293 9491129 YP_003804710.1 CDS Spirs_3014 NC_014364.1 3229681 3230433 R COGs: COG1402 Uncharacterized protein amidase; InterPro IPR003785; KEGG: aco:Amico_0022 creatininase; PFAM: creatininase; SPTR: uncharacterized protein; PFAM: Creatinine amidohydrolase; creatininase complement(3229681..3230433) Spirochaeta smaragdinae DSM 11293 9491130 YP_003804711.1 CDS Spirs_3015 NC_014364.1 3230438 3231928 R COGs: COG4145 Na+/panthothenate symporter; InterPro IPR001734; KEGG: lhk:LHK_00848 sodium/pantothenate symporter precursor; PFAM: Na+/solute symporter; SPTR: uncharacterized protein; PFAM: Sodium:solute symporter family; TIGRFAM: SSS sodium solute transporter superfamily; Na+/solute symporter complement(3230438..3231928) Spirochaeta smaragdinae DSM 11293 9491131 YP_003804712.1 CDS Spirs_3016 NC_014364.1 3231929 3232180 R KEGG: cro:ROD_15261 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3231929..3232180) Spirochaeta smaragdinae DSM 11293 9491132 YP_003804713.1 CDS Spirs_3017 NC_014364.1 3232387 3233238 D COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: tit:Thit_1138 transcriptional regulator, RpiR family; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator 3232387..3233238 Spirochaeta smaragdinae DSM 11293 9491133 YP_003804714.1 CDS Spirs_3018 NC_014364.1 3233235 3234356 R COGs: COG0044 dihydroorotase and related cyclic amidohydrolase; InterPro IPR010229:IPR006680; KEGG: tte:TTE0837 isoaspartyl dipeptidase; PFAM: amidohydrolase; SPTR: beta-aspartyl peptidase; TIGRFAM: isoaspartyl dipeptidase; PFAM: Amidohydrolase family; TIGRFAM: isoaspartyl dipeptidase IadA; isoaspartyl dipeptidase complement(3233235..3234356) Spirochaeta smaragdinae DSM 11293 9491134 YP_003804715.1 CDS Spirs_3019 NC_014364.1 3234393 3235208 R COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: cdf:CD0672 hypothetical protein; PFAM: protein of unknown function DUF34; SPTR: uncharacterized protein; PFAM: NIF3 (NGG1p interacting factor 3); hypothetical protein complement(3234393..3235208) Spirochaeta smaragdinae DSM 11293 9491135 YP_003804716.1 CDS Spirs_3020 NC_014364.1 3235356 3236495 D COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR010168:IPR002933:IPR011650:IPR017439; KEGG: nth:Nther_0781 amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: Amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase 3235356..3236495 Spirochaeta smaragdinae DSM 11293 9491136 YP_003804717.1 CDS Spirs_3021 NC_014364.1 3236739 3237398 R COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: mem:Memar_0474 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: methyltransferase domain; type 11 methyltransferase complement(3236739..3237398) Spirochaeta smaragdinae DSM 11293 9491137 YP_003804718.1 CDS Spirs_3022 NC_014364.1 3237453 3237992 R COGs: COG1695 transcriptional regulator protein; InterPro IPR005149; KEGG: sth:STH2076 transcriptional regulator; PFAM: transcriptional regulator PadR family protein; SPTR: transcriptional regulator; PFAM: transcriptional regulator PadR-like family; PadR family transcriptional regulator complement(3237453..3237992) Spirochaeta smaragdinae DSM 11293 9491138 YP_003804719.1 CDS Spirs_3023 NC_014364.1 3238374 3239072 R COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: rce:RC1_1835 translocator protein, LysE family protein; PFAM: lysine exporter (LYSE/YGGA); SPTR: translocator protein, LysE family protein; PFAM: LysE type translocator; lysine exporter LysE/YggA complement(3238374..3239072) Spirochaeta smaragdinae DSM 11293 9491139 YP_003804720.1 CDS Spirs_3025 NC_014364.1 3239623 3241188 R COGs: COG3920 Signal transduction histidine kinase; InterPro IPR011495:IPR003594; KEGG: rce:RC1_2648 sensory transduction histidine kinase, PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SPTR: sensory transduction histidine kinase, ; PFAM: histidine kinase; signal transduction histidine kinase complement(3239623..3241188) Spirochaeta smaragdinae DSM 11293 9491141 YP_003804721.1 CDS Spirs_3026 NC_014364.1 3241201 3242199 R COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389; KEGG: dde:Dde_0754 TRAP-type C4-dicarboxylate transporter periplasmic component-like; PFAM: extracellular solute-binding protein, family 7; SPTR: TRAP-type C4-dicarboxylate transporter periplasmic component-like; PFAM: Bacterial extracellular solute-binding protein, family 7; extracellular solute-binding protein, family 7 complement(3241201..3242199) Spirochaeta smaragdinae DSM 11293 9491142 YP_003804722.1 CDS Spirs_3027 NC_014364.1 3242600 3243625 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tna:CTN_1371 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3242600..3243625) Spirochaeta smaragdinae DSM 11293 9491143 YP_003804723.1 CDS Spirs_3028 NC_014364.1 3243696 3244970 R KEGG: sus:acid_6969 methyltransferase CmuC; SPTR: methyltransferase CmuC; PFAM: uroporphyrinogen decarboxylase (URO-D); methyltransferase CmuC complement(3243696..3244970) Spirochaeta smaragdinae DSM 11293 9491144 YP_003804724.1 CDS Spirs_3029 NC_014364.1 3244971 3246002 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: clo:HMPREF0868_0027 amino acid or sugar ABC transporter, permease protein; PFAM: inner-membrane translocator; SPTR: ribose transporter permease RbsC; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(3244971..3246002) Spirochaeta smaragdinae DSM 11293 9491145 YP_003804725.1 CDS Spirs_3030 NC_014364.1 3245999 3247564 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR003593:IPR017871; KEGG: clo:HMPREF0868_0026 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(3245999..3247564) Spirochaeta smaragdinae DSM 11293 9491146 YP_003804726.1 CDS Spirs_3031 NC_014364.1 3247592 3248554 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: gtn:GTNG_1813 D-ribose-binding periplasmic protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: D-ribose-binding periplasmic protein; PFAM: family; sugar ABC transporter periplasmic protein complement(3247592..3248554) Spirochaeta smaragdinae DSM 11293 9491147 YP_003804727.1 CDS Spirs_3032 NC_014364.1 3248822 3250060 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tex:Teth514_0159 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein complement(3248822..3250060) Spirochaeta smaragdinae DSM 11293 9491148 YP_003804728.1 CDS Spirs_3033 NC_014364.1 3250485 3251360 D KEGG: csa:Csal_1702 hypothetical protein; SPTR: uncharacterized protein; PFAM: transposase, YhgA-like; TIGRFAM: conserved hypothetical protein ( transposase or invertase); hypothetical protein 3250485..3251360 Spirochaeta smaragdinae DSM 11293 9491149 YP_003804729.1 CDS Spirs_3034 NC_014364.1 3251457 3252242 R InterPro IPR002781; KEGG: bhy:BHWA1_00805 hypothetical protein; PFAM: protein of unknown function DUF81; SPTR: uncharacterized protein; PFAM: Sulfite exporter TauE/SafE; hypothetical protein complement(3251457..3252242) Spirochaeta smaragdinae DSM 11293 9491150 YP_003804730.1 CDS Spirs_3035 NC_014364.1 3252286 3253554 R COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197:IPR004027; KEGG: mma:MM_1893 transcriptional regulator; PFAM: radical SAM protein; SEC-C motif domain protein; SPTR: Arylsulfatase regulator; PFAM: radical SAM superfamily; SEC-C motif; radical SAM protein complement(3252286..3253554) Spirochaeta smaragdinae DSM 11293 9491151 YP_003804731.1 CDS Spirs_3036 NC_014364.1 3253737 3255254 R COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: smd:Smed_2068 sulfatase; PFAM: sulfatase; SPTR: Sulfatase; PFAM: Sulfatase; sulfatase complement(3253737..3255254) Spirochaeta smaragdinae DSM 11293 9491152 YP_003804732.1 CDS Spirs_3037 NC_014364.1 3255282 3256775 R COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: pmr:PMI2935 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: Trap-t family transporter large; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein complement(3255282..3256775) Spirochaeta smaragdinae DSM 11293 9491153 YP_003804733.1 CDS Spirs_3038 NC_014364.1 3256785 3257288 R KEGG: amt:Amet_3083 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3256785..3257288) Spirochaeta smaragdinae DSM 11293 9491154 YP_003804734.1 CDS Spirs_3039 NC_014364.1 3257362 3258375 R COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: ctt:CtCNB1_1673 TctC; PFAM: conserved hypothetical protein; SPTR: secreted protein; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein complement(3257362..3258375) Spirochaeta smaragdinae DSM 11293 9491155 YP_003804735.1 CDS Spirs_3040 NC_014364.1 3258544 3259446 D COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: tau:Tola_1238 transcriptional regulator, LysR family; PFAM: regulatory protein LysR; LysR substrate-binding; SPTR: LysR family transcriptional regulator; manually curated; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator 3258544..3259446 Spirochaeta smaragdinae DSM 11293 9491156 YP_003804736.1 CDS Spirs_3041 NC_014364.1 3259482 3260738 D COGs: COG4905 membrane protein; InterPro IPR006675:IPR010540; KEGG: cth:Cthe_1851 hypothetical protein; PFAM: protein of unknown function DUF1113; SPTR: uncharacterized protein; TIGRFAM: metal dependent phophohydrolase; PFAM: protein of unknown function (DUF1113); TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase 3259482..3260738 Spirochaeta smaragdinae DSM 11293 9491157 YP_003804737.1 CDS Spirs_3042 NC_014364.1 3261030 3261587 D InterPro IPR002610; KEGG: aoe:Clos_1948 rhomboid family protein; PFAM: rhomboid family protein; SPTR: Rhomboid (Drosophila) related protein 1, ; PFAM: Rhomboid family; rhomboid family protein 3261030..3261587 Spirochaeta smaragdinae DSM 11293 9491159 YP_003804738.1 CDS Spirs_3043 NC_014364.1 3261615 3263180 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792; KEGG: lbf:LBF_2609 serine phosphatase RsbU, regulator of sigma subunit; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: phosphoserine phosphatase; membrane protein; PFAM: 7TM diverse intracellular signalling; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(3261615..3263180) Spirochaeta smaragdinae DSM 11293 9491160 YP_003804739.1 CDS Spirs_3044 NC_014364.1 3263303 3263470 D hypothetical protein 3263303..3263470 Spirochaeta smaragdinae DSM 11293 9491161 YP_003804740.1 CDS Spirs_3045 NC_014364.1 3263474 3264541 D COGs: COG0216 protein chain release factor A; InterPro IPR004373:IPR005139:IPR000352; KEGG: tde:TDE2489 peptide chain release factor 1; PFAM: class I peptide chain release factor; PCRF domain protein; SPTR: peptide chain release factor 1; TIGRFAM: peptide chain release factor 1; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1; peptide chain release factor 1 3263474..3264541 Spirochaeta smaragdinae DSM 11293 9491162 YP_003804741.1 CDS Spirs_3046 NC_014364.1 3264541 3265470 D COGs: COG2890 methylase of polypeptide chain release factors; InterPro IPR004556:IPR019874:IPR007848:IPR002052; KEGG: mxa:MXAN_4908 protein methyltransferase HemK; PFAM: methyltransferase small; SPTR: methyltransferase, HemK family; TIGRFAM: protein-(glutamine-N5) methyltransferase, release factor-specific; modification methylase, HemK family; PFAM: methyltransferase small domain; TIGRFAM: HemK family methylases; protein-(glutamine-N5) methyltransferase, release factor-specific; protein-(glutamine-N5) methyltransferase, release factor-specific 3264541..3265470 Spirochaeta smaragdinae DSM 11293 9491163 YP_003804742.1 CDS Spirs_3047 NC_014364.1 3265477 3267483 D COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR004811:IPR006674:IPR007685:IPR004095:IPR 003607; KEGG: ddf:DEFDS_0048 GTP pyrophosphokinase; PFAM: RelA/SpoT domain protein; metal-dependent phosphohydrolase HD sub domain; TGS domain protein; PRIAM: GTP diphosphokinase; SMART: metal-dependent phosphohydrolase HD region; SPTR: GTP pyrophosphokinase; TIGRFAM: RelA/SpoT family protein; PFAM: HD domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family; (p)ppGpp synthetase I SpoT/RelA 3265477..3267483 Spirochaeta smaragdinae DSM 11293 9491164 YP_003804743.1 CDS Spirs_3048 NC_014364.1 3267516 3268109 R KEGG: tde:TDE2435 hypothetical protein; SPTR: Conserved domain protein; hypothetical protein complement(3267516..3268109) Spirochaeta smaragdinae DSM 11293 9491165 YP_003804744.1 CDS Spirs_3049 NC_014364.1 3268114 3269370 R InterPro IPR011701; KEGG: cno:NT01CX_1080 major facilitator superfamily protein; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily protein; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(3268114..3269370) Spirochaeta smaragdinae DSM 11293 9491166 YP_003804745.1 CDS Spirs_3050 NC_014364.1 3269379 3270488 R COGs: COG0012 GTPase probable translation factor; InterPro IPR004396:IPR002917:IPR013029:IPR006073; KEGG: tde:TDE0305 GTP-dependent nucleic acid-binding protein EngD; PFAM: protein of unknown function DUF933; GTP-binding protein HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: GTP-binding protein YchF; PFAM: GTPase of unknown function; protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF; GTP-binding protein YchF complement(3269379..3270488) Spirochaeta smaragdinae DSM 11293 9491167 YP_003804746.1 CDS Spirs_3051 NC_014364.1 3270566 3272020 D COGs: COG2925 exonuclease I; InterPro IPR013520:IPR013620:IPR006055; KEGG: cja:CJA_2637 exonuclease I; PFAM: exonuclease domain protein; exonuclease RNase T and DNA polymerase III; PRIAM: exodeoxyribonuclease I; SMART: exonuclease; SPTR: exodeoxyribonuclease I; PFAM: exonuclease; exonuclease C-terminal; exodeoxyribonuclease I 3270566..3272020 Spirochaeta smaragdinae DSM 11293 9491168 YP_003804747.1 CDS Spirs_3052 NC_014364.1 3272288 3273475 R COGs: COG0701 permease; InterPro IPR005524; KEGG: hor:Hore_20090 permease; PFAM: permease; SPTR: Permease; PFAM: Predicted permease; permease complement(3272288..3273475) Spirochaeta smaragdinae DSM 11293 9491169 YP_003804748.1 CDS Spirs_3053 NC_014364.1 3273477 3273731 R InterPro IPR005243; KEGG: dps:DP0946 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: redox-active disulfide protein 2; TIGRFAM: small redox-active disulfide protein 2; redox-active disulfide protein 2 complement(3273477..3273731) Spirochaeta smaragdinae DSM 11293 9491170 YP_003804749.1 CDS Spirs_3054 NC_014364.1 3273852 3274172 D InterPro IPR001845; KEGG: swp:swp_0625 regulatory protein, ArsR; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: Regulatory protein, ArsR; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 3273852..3274172 Spirochaeta smaragdinae DSM 11293 9491171 YP_003804750.1 CDS Spirs_3055 NC_014364.1 3274177 3274371 R KEGG: drm:Dred_0592 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3274177..3274371) Spirochaeta smaragdinae DSM 11293 9491172 YP_003804751.1 CDS Spirs_3056 NC_014364.1 3274364 3275674 R InterPro IPR011701; KEGG: rba:RB3032 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(3274364..3275674) Spirochaeta smaragdinae DSM 11293 9491173 YP_003804752.1 CDS Spirs_3057 NC_014364.1 3275825 3276820 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: dth:DICTH_1623 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3275825..3276820) Spirochaeta smaragdinae DSM 11293 9491174 YP_003804753.1 CDS Spirs_3058 NC_014364.1 3277163 3279040 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR005834; KEGG: dfe:Dfer_4313 PfkB domain protein; PFAM: PfkB domain protein; haloacid dehalogenase; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; haloacid dehalogenase-like hydrolase; PfkB domain-containing protein 3277163..3279040 Spirochaeta smaragdinae DSM 11293 9491175 YP_003804754.1 CDS Spirs_3059 NC_014364.1 3279047 3280150 D KEGG: dsa:Desal_0564 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3279047..3280150 Spirochaeta smaragdinae DSM 11293 9491176 YP_003804755.1 CDS Spirs_3060 NC_014364.1 3280153 3281439 D COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: dfe:Dfer_5652 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase 3280153..3281439 Spirochaeta smaragdinae DSM 11293 9491177 YP_003804756.1 CDS Spirs_3061 NC_014364.1 3281492 3282763 D COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: kol:Kole_2003 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein 3281492..3282763 Spirochaeta smaragdinae DSM 11293 9491178 YP_003804757.1 CDS Spirs_3062 NC_014364.1 3282845 3283738 D COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: kol:Kole_2002 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease 3282845..3283738 Spirochaeta smaragdinae DSM 11293 9491179 YP_003804758.1 CDS Spirs_3063 NC_014364.1 3283735 3284556 D COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tna:CTN_0662 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 3283735..3284556 Spirochaeta smaragdinae DSM 11293 9491180 YP_003804759.1 CDS Spirs_3064 NC_014364.1 3284566 3285513 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tte:TTE0761 transcriptional regulator; PFAM: ROK family protein; SPTR: transcriptional regulator; PFAM: ROK family; TIGRFAM: ROK family protein ( glucokinase); ROK family protein 3284566..3285513 Spirochaeta smaragdinae DSM 11293 9491181 YP_003804760.1 CDS Spirs_3065 NC_014364.1 3285503 3286138 D COGs: COG0279 phosphoheptose isomerase; InterPro IPR001347; KEGG: tte:TTE0762 phosphoheptose isomerase; PFAM: sugar isomerase (SIS); SPTR: uncharacterized protein; PFAM: SIS domain; sugar isomerase (SIS) 3285503..3286138 Spirochaeta smaragdinae DSM 11293 9491182 YP_003804761.1 CDS Spirs_3066 NC_014364.1 3286146 3286328 R InterPro IPR017896:IPR001450:IPR017900; KEGG: hor:Hore_20120 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: 4Fe-4S binding domain; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein complement(3286146..3286328) Spirochaeta smaragdinae DSM 11293 9491183 YP_003804762.1 CDS Spirs_3067 NC_014364.1 3286459 3287988 R KEGG: sli:Slin_6468 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3286459..3287988) Spirochaeta smaragdinae DSM 11293 9491184 YP_003804763.1 CDS Spirs_3069 NC_014364.1 3289647 3290900 R KEGG: nml:Namu_3503 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3289647..3290900) Spirochaeta smaragdinae DSM 11293 9491186 YP_003804764.1 CDS Spirs_3070 NC_014364.1 3290923 3292074 R KEGG: chu:CHU_1075 beta-glycosidase-like protein; SPTR: Outer membrane autotransporter barrel; hypothetical protein complement(3290923..3292074) Spirochaeta smaragdinae DSM 11293 9491187 YP_003804765.1 CDS Spirs_3071 NC_014364.1 3292071 3292616 R KEGG: xca:xccb100_1409 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3292071..3292616) Spirochaeta smaragdinae DSM 11293 9491188 YP_003804766.1 CDS Spirs_3072 NC_014364.1 3292625 3295780 R COGs: COG0666 FOG: ankyrin repeat; InterProIPR002110:IPR003646:IPR020683:IPR010466:IPR 011600:IPR018247:IPR001917; KEGG: sit:TM1040_0843 OmpA/MotB; PFAM: peptidase C14 caspase catalytic subunit p20; ankyrin; protein of unknown function DUF1058; SMART: SH3 domain protein; ankyrin; SPTR: uncharacterized protein; PFAM: Caspase domain; Bacterial SH3 domain; ankyrin repeat; peptidase C14 caspase catalytic subunit p20 complement(3292625..3295780) Spirochaeta smaragdinae DSM 11293 9491189 YP_003804767.1 CDS Spirs_3073 NC_014364.1 3296151 3296567 R KEGG: dwi:Dwil_GK11253 GK11253 gene product from transcript GK11253-RA; SPTR: uncharacterized protein; hypothetical protein complement(3296151..3296567) Spirochaeta smaragdinae DSM 11293 9491190 YP_003804768.1 CDS Spirs_3074 NC_014364.1 3296574 3297005 R COGs: COG2166 SufE protein probably involved in Fe-S center assembly; InterPro IPR003808; KEGG: coc:Coch_0938 Fe-S metabolism associated SufE; PFAM: Fe-S metabolism associated SufE; SPTR: cysteine desulfuration protein SufE; PFAM: Fe-S metabolism associated domain; Fe-S metabolism associated SufE complement(3296574..3297005) Spirochaeta smaragdinae DSM 11293 9491191 YP_003804769.1 CDS Spirs_3075 NC_014364.1 3297002 3298228 R COGs: COG0520 Selenocysteine lyase; InterPro IPR000192:IPR000923:IPR020578; KEGG: rmr:Rmar_2025 cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; SPTR: cysteine desulfurase; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily; class V aminotransferase complement(3297002..3298228) Spirochaeta smaragdinae DSM 11293 9491192 YP_003804770.1 CDS Spirs_3076 NC_014364.1 3298247 3299791 R KEGG: hbu:Hbut_1397 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3298247..3299791) Spirochaeta smaragdinae DSM 11293 9491193 YP_003804771.1 CDS Spirs_3077 NC_014364.1 3299889 3301130 R InterPro IPR011701; KEGG: cdl:CDR20291_2963 nitrate/nitrite transporter; PFAM: major facilitator superfamily MFS_1; SPTR: nitrate/nitrite transporter; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(3299889..3301130) Spirochaeta smaragdinae DSM 11293 9491194 YP_003804772.1 CDS Spirs_3078 NC_014364.1 3301146 3302615 R COGs: COG0644 dehydrogenase (flavoprotein); InterPro IPR003953:IPR001327; KEGG: tpd:Teth39_1811 glucose-inhibited division protein A; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: invasion protein IbeA; PFAM: FAD binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein complement(3301146..3302615) Spirochaeta smaragdinae DSM 11293 9491195 YP_003804773.1 CDS Spirs_3079 NC_014364.1 3302630 3304330 R KEGG: mth:MTH1540 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3302630..3304330) Spirochaeta smaragdinae DSM 11293 9491196 YP_003804774.1 CDS Spirs_3080 NC_014364.1 3304334 3304477 R KEGG: dgr:Dgri_GH10992 GH10992 gene product from transcript GH10992-RA; hypothetical protein complement(3304334..3304477) Spirochaeta smaragdinae DSM 11293 9491197 YP_003804775.1 CDS Spirs_3081 NC_014364.1 3304736 3305794 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: cbe:Cbei_1380 periplasmic binding protein/LacI transcriptional regulator; SPTR: uncharacterized protein; sugar ABC transporter periplasmic protein complement(3304736..3305794) Spirochaeta smaragdinae DSM 11293 9491198 YP_003804776.1 CDS Spirs_3082 NC_014364.1 3305819 3306802 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: str:Sterm_3539 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; sugar ABC transporter permease complement(3305819..3306802) Spirochaeta smaragdinae DSM 11293 9491199 YP_003804777.1 CDS Spirs_3083 NC_014364.1 3306806 3308296 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: msu:MS0062 L-arabinose transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter complement(3306806..3308296) Spirochaeta smaragdinae DSM 11293 9491200 YP_003804778.1 CDS Spirs_3084 NC_014364.1 3308305 3309801 R COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016160; KEGG: msi:Msm_0467 NADP-dependent glyceraldehyde-3-phosphate dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: succinate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase family; aldehyde dehydrogenase complement(3308305..3309801) Spirochaeta smaragdinae DSM 11293 9491201 YP_003804779.1 CDS Spirs_3085 NC_014364.1 3309814 3311043 R COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR000169:IPR018211; KEGG: ere:EUBREC_0100 alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase complement(3309814..3311043) Spirochaeta smaragdinae DSM 11293 9491202 YP_003804780.1 CDS Spirs_3086 NC_014364.1 3311215 3312126 R COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sga:GALLO_0047 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator complement(3311215..3312126) Spirochaeta smaragdinae DSM 11293 9491203 YP_003804781.1 CDS Spirs_3087 NC_014364.1 3312365 3313654 D COGs: COG2262 GTPase; InterPro IPR016496:IPR006073:IPR002917; KEGG: ote:Oter_4111 GTP-binding protein HflX; PFAM: GTP-binding protein HSR1-related; SPTR: uncharacterized protein; TIGRFAM: GTP-binding proten HflX; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX; small GTP-binding protein domain; GTP-binding proten HflX 3312365..3313654 Spirochaeta smaragdinae DSM 11293 9491204 YP_003804782.1 CDS Spirs_3088 NC_014364.1 3313666 3314664 D COGs: COG2355 Zn-dependent dipeptidase microsomal dipeptidase homolog; InterPro IPR008257:IPR000180; KEGG: nca:Noca_0081 peptidase M19, renal dipeptidase; PFAM: peptidase M19 renal dipeptidase; PRIAM: membrane dipeptidase; SPTR: membrane dipeptidase; PFAM: membrane dipeptidase (peptidase family M19); membrane dipeptidase 3313666..3314664 Spirochaeta smaragdinae DSM 11293 9491205 YP_003804783.1 CDS Spirs_3089 NC_014364.1 3314661 3315074 D KEGG: nmu:Nmul_A2680 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of Unknown function (DUF2784); hypothetical protein 3314661..3315074 Spirochaeta smaragdinae DSM 11293 9491206 YP_003804784.1 CDS Spirs_3090 NC_014364.1 3315000 3315890 R InterPro IPR000620; KEGG: gfo:GFO_1972 hypothetical protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: membrane protein containing DUF6; PFAM: EamA-like transporter family; hypothetical protein complement(3315000..3315890) Spirochaeta smaragdinae DSM 11293 9491207 YP_003804785.1 CDS Spirs_3091 NC_014364.1 3315887 3316426 R KEGG: dth:DICTH_0124 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3315887..3316426) Spirochaeta smaragdinae DSM 11293 9491208 YP_003804786.1 CDS Spirs_3092 NC_014364.1 3316429 3316725 R KEGG: pab:PAB0793 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3316429..3316725) Spirochaeta smaragdinae DSM 11293 9491209 YP_003804787.1 CDS Spirs_3093 NC_014364.1 3316770 3316991 R KEGG: gur:Gura_0021 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3316770..3316991) Spirochaeta smaragdinae DSM 11293 9491210 YP_003804788.1 CDS Spirs_3094 NC_014364.1 3317109 3319283 D COGs: COG2217 Cation transport ATPase; InterProIPR006121:IPR001757:IPR001366:IPR008250:IPR 005834:IPR006403:IPR006416:IPR018303:IPR017969; KEGG: pmo:Pmob_0715 heavy metal translocating P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase P; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; ATPase P; ATPase P; ATPase P 3317109..3319283 Spirochaeta smaragdinae DSM 11293 9491211 YP_003804789.1 CDS Spirs_3095 NC_014364.1 3319280 3319483 D InterPro IPR006121; KEGG: pmo:Pmob_0716 heavy metal transport/detoxification protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Heavy metal transport/detoxification protein; PFAM: Heavy-metal-associated domain; Heavy metal transport/detoxification protein 3319280..3319483 Spirochaeta smaragdinae DSM 11293 9491212 YP_003804790.1 CDS Spirs_3096 NC_014364.1 3319491 3319901 R COGs: COG0784 FOG: CheY-like receiver; InterPro IPR001789; KEGG: shn:Shewana3_2015 PAS/PAC sensor protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3319491..3319901) Spirochaeta smaragdinae DSM 11293 9491213 YP_003804791.1 CDS Spirs_3097 NC_014364.1 3319898 3321661 R KEGG: pop:POPTR_290317 hypothetical protein; SPTR: Predicted protein; hypothetical protein complement(3319898..3321661) Spirochaeta smaragdinae DSM 11293 9491214 YP_003804792.1 CDS Spirs_3098 NC_014364.1 3321881 3323326 R COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: adg:Adeg_1545 radical SAM protein; PFAM: radical SAM domain protein; SPTR: radical SAM protein; PFAM: radical SAM superfamily; radical SAM protein complement(3321881..3323326) Spirochaeta smaragdinae DSM 11293 9491215 YP_003804793.1 CDS Spirs_3099 NC_014364.1 3323417 3324049 R InterPro IPR001647; KEGG: bld:BLi03107 YttP; PFAM: regulatory protein TetR; SPTR: transcriptional regulator YttP; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(3323417..3324049) Spirochaeta smaragdinae DSM 11293 9491216 YP_003804794.1 CDS Spirs_3101 NC_014364.1 3324912 3326084 R COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: dde:Dde_0966 metal dependent phosphohydrolase; PFAM: protein of unknown function DUF1113; SPTR: metal dependent phosphohydrolase; PFAM: protein of unknown function (DUF1113); hypothetical protein complement(3324912..3326084) Spirochaeta smaragdinae DSM 11293 9491218 YP_003804795.1 CDS Spirs_3103 NC_014364.1 3326352 3326456 R hypothetical protein complement(3326352..3326456) Spirochaeta smaragdinae DSM 11293 9491220 YP_003804796.1 CDS Spirs_3104 NC_014364.1 3326453 3326902 R COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: rba:RB8584 PTS system, fructose-specific enzyme II, BC component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; PTS IIA-like nitrogen-regulatory protein PtsN complement(3326453..3326902) Spirochaeta smaragdinae DSM 11293 9491221 YP_003804797.1 CDS Spirs_3105 NC_014364.1 3326918 3327403 R InterPro IPR006016; KEGG: htu:Htur_0973 UspA domain protein; PFAM: UspA domain protein; SPTR: UspA domain protein; PFAM: Universal stress protein family; UspA domain-containing protein complement(3326918..3327403) Spirochaeta smaragdinae DSM 11293 9491222 YP_003804798.1 CDS Spirs_3106 NC_014364.1 3327387 3328034 R COGs: COG1394 H+-ATPase D; InterPro IPR002699; KEGG: hor:Hore_19380 V-type ATP synthase subunit D; PFAM: H+transporting two-sector ATPase D subunit; SPTR: V-type ATP synthase subunit D; TIGRFAM: V-type ATPase, D subunit; PFAM: ATP synthase subunit D; TIGRFAM: H(+)-transporting ATP synthase, vacuolar type, subunit D; V-type ATPase subunit D complement(3327387..3328034) Spirochaeta smaragdinae DSM 11293 9491223 YP_003804799.1 CDS Spirs_3107 NC_014364.1 3328040 3329437 R COGs: COG1156 H+-ATPase B; InterPro IPR004100:IPR000194:IPR000793; KEGG: hor:Hore_19390 V-type ATP synthase subunit B; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; SPTR: V-type ATP synthase beta chain; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; H+transporting two-sector ATPase alpha/subunit beta central region complement(3328040..3329437) Spirochaeta smaragdinae DSM 11293 9491224 YP_003804800.1 CDS Spirs_3108 NC_014364.1 3329424 3331202 R COGs: COG1155 H+-ATPase A; InterPro IPR004100:IPR000194:IPR000793; KEGG: hor:Hore_19400 V-type ATP synthase subunit A; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; H+transporting two-sector ATPase alpha/subunit beta domain protein; PRIAM: Sodium-transporting two-sector ATPase; SPTR: V-type ATP synthase alpha chain; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; Sodium-transporting two-sector ATPase complement(3329424..3331202) Spirochaeta smaragdinae DSM 11293 9491225 YP_003804801.1 CDS Spirs_3109 NC_014364.1 3331199 3331822 R InterPro IPR002842; KEGG: pab:PAB1182 V-type ATP synthase subunit E; PFAM: H+transporting two-sector ATPase E subunit; SPTR: V-type ATP synthase subunit E; PFAM: ATP synthase (E/31 kDa) subunit; H+transporting two-sector ATPase E subunit complement(3331199..3331822) Spirochaeta smaragdinae DSM 11293 9491226 YP_003804802.1 CDS Spirs_3110 NC_014364.1 3331837 3332142 R COGs: COG1436 H+-ATPase F; InterPro IPR008218; KEGG: cpy:Cphy_3444 vacuolar H+transporting two-sector ATPase F subunit; PFAM: Vacuolar H+transporting two-sector ATPase F subunit; SPTR: ATP synthase subunit; PFAM: ATP synthase (F/14-kDa) subunit; Vacuolar H+transporting two-sector ATPase F subunit complement(3331837..3332142) Spirochaeta smaragdinae DSM 11293 9491227 YP_003804803.1 CDS Spirs_3111 NC_014364.1 3332152 3332532 R InterPro IPR000454:IPR000245:IPR002379; KEGG: trq:TRQ2_1105 H+transporting two-sector ATPase C subunit; PFAM: H+transporting two-sector ATPase C subunit; SPTR: H+transporting two-sector ATPase C subunit; PFAM: ATP synthase subunit C; H+transporting two-sector ATPase C subunit complement(3332152..3332532) Spirochaeta smaragdinae DSM 11293 9491228 YP_003804804.1 CDS Spirs_3112 NC_014364.1 3332551 3334533 R COGs: COG1269 H+-ATPase I; InterPro IPR002490; KEGG: hor:Hore_19440 H(+)-transporting two-sector ATPase; PFAM: V-type ATPase 116 kDa subunit; SPTR: V-type ATP synthase, subunit I; PFAM: V-type ATPase 116kDa subunit family; V-type ATPase 116 kDa subunit complement(3332551..3334533) Spirochaeta smaragdinae DSM 11293 9491229 YP_003804805.1 CDS Spirs_3113 NC_014364.1 3334530 3335585 R COGs: COG1527 H+-ATPase C; InterPro IPR002843; KEGG: nph:NP1026A V-type ATP synthase subunit C; PFAM: H+transporting two-sector ATPase C (AC39) subunit; SPTR: H(+)-transporting two-sector ATPase C.a (A-type ATP synthase); PFAM: ATP synthase (C/AC39) subunit; H+transporting two-sector ATPase C (AC39) subunit complement(3334530..3335585) Spirochaeta smaragdinae DSM 11293 9491230 YP_003804806.1 CDS Spirs_3114 NC_014364.1 3335591 3335911 R KEGG: tko:TK1596 V-type ATP synthase subunit H; SPTR: Archaeal/vacuolar-type H+-ATPase, subunit H; hypothetical protein complement(3335591..3335911) Spirochaeta smaragdinae DSM 11293 9491231 YP_003804807.1 CDS Spirs_3115 NC_014364.1 3335939 3336436 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR002373:IPR018488; KEGG: tde:TDE2437 cyclic nucleotide binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide binding domain protein; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator complement(3335939..3336436) Spirochaeta smaragdinae DSM 11293 9491232 YP_003804808.1 CDS Spirs_3116 NC_014364.1 3336433 3337695 R InterPro IPR003091:IPR013099:IPR003148; KEGG: tde:TDE2438 hypothetical protein; PFAM: ion transport 2 domain protein ; TrkA-N domain protein; SPTR: uncharacterized protein; PFAM: ion channel; TrkA-N domain; ion transport 2 domain-containing protein complement(3336433..3337695) Spirochaeta smaragdinae DSM 11293 9491233 YP_003804809.1 CDS Spirs_3117 NC_014364.1 3338085 3339416 R COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: tle:Tlet_1725 gluconate transporter; PFAM: gluconate transporter; SPTR: GntP family permease; PFAM: GntP family permease; TIGRFAM: gluconate transporter; gluconate transporter complement(3338085..3339416) Spirochaeta smaragdinae DSM 11293 9491234 YP_003804810.1 CDS Spirs_3118 NC_014364.1 3339509 3340375 R COGs: COG0652 peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: lic:LIC11839 peptidyl-prolyl cis-trans isomerase; PFAM: peptidyl-prolyl cis-trans isomerase cyclophilin type; SPTR: peptidyl-prolyl cis-trans isomerase; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD; cyclophilin type peptidyl-prolyl cis-trans isomerase complement(3339509..3340375) Spirochaeta smaragdinae DSM 11293 9491235 YP_003804811.1 CDS Spirs_3119 NC_014364.1 3340462 3341082 D COGs: COG1678 transcriptional regulator protein; InterPro IPR003774; KEGG: cwo:Cwoe_0090 protein of unknown function DUF179; PFAM: protein of unknown function DUF179; SPTR: uncharacterized protein; PFAM: Uncharacterized ACR, COG1678; hypothetical protein 3340462..3341082 Spirochaeta smaragdinae DSM 11293 9491236 YP_003804812.1 CDS Spirs_3120 NC_014364.1 3341171 3342289 D KEGG: bba:Bd2578 transposase; SPTR: uncharacterized protein; hypothetical protein 3341171..3342289 Spirochaeta smaragdinae DSM 11293 9491237 YP_003804813.1 CDS Spirs_3121 NC_014364.1 3342422 3343288 D InterPro IPR007197; KEGG: hma:rrnAC2164 hypothetical protein; PFAM: radical SAM protein; SPTR: uncharacterized protein; PFAM: radical SAM superfamily; radical SAM protein 3342422..3343288 Spirochaeta smaragdinae DSM 11293 9491238 YP_003804814.1 CDS Spirs_3122 NC_014364.1 3343306 3343860 R COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR002779; KEGG: amt:Amet_2904 ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: uncharacterized protein; TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase; ATP/cobalamin adenosyltransferase complement(3343306..3343860) Spirochaeta smaragdinae DSM 11293 9491239 YP_003804815.1 CDS Spirs_3123 NC_014364.1 3343949 3345814 R COGs: COG0151 phosphoribosylamine-glycine ligase; InterProIPR000115:IPR011761:IPR002376:IPR020562:IPR 020561:IPR020560:IPR004607:IPR020559:IPR001555; KEGG: pmj:P9211_13941 phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; formyl transferase; phosphoribosylglycinamide synthetase, N-domain; phosphoribosylglycinamide synthetase, C-domain; SPTR: phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; phosphoribosylglycinamide formyltransferase; PFAM: phosphoribosylglycinamide synthetase, N domain; phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Formyl transferase; phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent; phosphoribosylamine/glycine ligase complement(3343949..3345814) Spirochaeta smaragdinae DSM 11293 9491240 YP_003804816.1 CDS Spirs_3124 NC_014364.1 3345802 3346857 R COGs: COG0150 phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR000728:IPR010918:IPR004733; KEGG: cby:CLM_3272 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: phosphoribosylformylglycinamidine cyclo-ligase; SPTR: phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase; phosphoribosylformylglycinamidine cyclo-ligase complement(3345802..3346857) Spirochaeta smaragdinae DSM 11293 9491241 YP_003804817.1 CDS Spirs_3125 NC_014364.1 3346857 3348302 R COGs: COG0034 glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854:IPR017932:IPR000583:IPR000836; KEGG: cbb:CLD_1664 amidophosphoribosyltransferase; PFAM: glutamine amidotransferase class-II; phosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: amidophosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase; amidophosphoribosyltransferase complement(3346857..3348302) Spirochaeta smaragdinae DSM 11293 9491242 YP_003804818.1 CDS Spirs_3126 NC_014364.1 3348295 3349008 R COGs: COG0152 phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636:IPR018236; KEGG: cbe:Cbei_1055 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; phosphoribosylaminoimidazole-succinocarboxamide synthase complement(3348295..3349008) Spirochaeta smaragdinae DSM 11293 9491243 YP_003804819.1 CDS Spirs_3127 NC_014364.1 3349005 3349490 R COGs: COG0041 phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: pab:PAB1077 phosphoribosylaminoimidazole carboxylase catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; PRIAM: phosphoribosylaminoimidazole carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein; phosphoribosylaminoimidazole carboxylase, catalytic subunit complement(3349005..3349490) Spirochaeta smaragdinae DSM 11293 9491244 YP_003804820.1 CDS Spirs_3128 NC_014364.1 3349514 3353236 R COGs: COG0046 phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR000728:IPR010918:IPR010141; KEGG: cth:Cthe_0554 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein; PRIAM: phosphoribosylformylglycinamidine synthase; SPTR: phosphoribosylformylglycinamidine synthase; TIGRFAM: phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II; phosphoribosylformylglycinamidine synthase complement(3349514..3353236) Spirochaeta smaragdinae DSM 11293 9491245 YP_003804821.1 CDS Spirs_3129 NC_014364.1 3353516 3354271 R InterPro IPR013217; KEGG: aoe:Clos_0075 methyltransferase type 11; PFAM: methyltransferase type 12; SPTR: methyltransferase type 11; PFAM: methyltransferase domain; type 12 methyltransferase complement(3353516..3354271) Spirochaeta smaragdinae DSM 11293 9491246 YP_003804822.1 CDS Spirs_3130 NC_014364.1 3354394 3355578 D COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: cts:Ctha_1055 STE24 endopeptidase; PFAM: peptidase M48 Ste24p; PRIAM: Ste24 endopeptidase; SPTR: Ste24 endopeptidase; PFAM: peptidase family M48; Ste24 endopeptidase 3354394..3355578 Spirochaeta smaragdinae DSM 11293 9491247 YP_003804823.1 CDS Spirs_3131 NC_014364.1 3355635 3356495 D KEGG: fra:Francci3_0226 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3355635..3356495 Spirochaeta smaragdinae DSM 11293 9491248 YP_003804824.1 CDS Spirs_3132 NC_014364.1 3356535 3357542 D KEGG: psl:Psta_4683 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein; hypothetical protein 3356535..3357542 Spirochaeta smaragdinae DSM 11293 9491249 YP_003804825.1 CDS Spirs_3133 NC_014364.1 3357921 3358718 D COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583; KEGG: rrs:RoseRS_1153 inositol-phosphate phosphatase; PFAM: inositol monophosphatase; SPTR: inositol-phosphate phosphatase; PFAM: inositol monophosphatase family; inositol monophosphatase 3357921..3358718 Spirochaeta smaragdinae DSM 11293 9491250 YP_003804826.1 CDS Spirs_3134 NC_014364.1 3358751 3360490 D COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR000873; KEGG: tde:TDE0942 long-chain-fatty-acid--CoA ligase, PFAM: AMP-dependent synthetase and ligase; SPTR: long-chain-fatty-acid--CoA ligase; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase 3358751..3360490 Spirochaeta smaragdinae DSM 11293 9491251 YP_003804827.1 CDS Spirs_3135 NC_014364.1 3360487 3361239 D COGs: COG0778 nitroreductase; InterPro IPR016446:IPR000415; KEGG: dsy:DSY1460 hypothetical protein; PFAM: nitroreductase; SPTR: nitro/flavin reductase; PFAM: nitroreductase family; nitroreductase 3360487..3361239 Spirochaeta smaragdinae DSM 11293 9491252 YP_003804828.1 CDS Spirs_3136 NC_014364.1 3361223 3361915 R COGs: COG1738 conserved hypothetical protein; InterPro IPR003744; KEGG: taf:THA_234 transporter; PFAM: protein of unknown function DUF165; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein; PFAM: Uncharacterized ACR, YhhQ family COG1738; TIGRFAM: conserved hypothetical integral membrane protein; hypothetical protein complement(3361223..3361915) Spirochaeta smaragdinae DSM 11293 9491253 YP_003804829.1 CDS Spirs_3137 NC_014364.1 3361908 3362789 R KEGG: tde:TDE0304 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3361908..3362789) Spirochaeta smaragdinae DSM 11293 9491254 YP_003804830.1 CDS Spirs_3138 NC_014364.1 3362790 3363665 R KEGG: cts:Ctha_2398 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3362790..3363665) Spirochaeta smaragdinae DSM 11293 9491255 YP_003804831.1 CDS Spirs_3139 NC_014364.1 3363795 3364628 D KEGG: srm:SRM_01003 hypothetical protein, membrane or secreted; SPTR: DESERT; hypothetical protein 3363795..3364628 Spirochaeta smaragdinae DSM 11293 9491256 YP_003804832.1 CDS Spirs_3140 NC_014364.1 3364984 3366072 D COGs: COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis; InterPro IPR004516:IPR002314; KEGG: amt:Amet_0570 histidine--tRNA ligase; PFAM: tRNA synthetase class II (G H P and S); SPTR: uncharacterized protein; tRNA synthetase class II (G H P and S) 3364984..3366072 Spirochaeta smaragdinae DSM 11293 9491257 YP_003804833.1 CDS Spirs_3141 NC_014364.1 3366082 3366723 D COGs: COG0040 ATP phosphoribosyltransferase; InterPro IPR013820:IPR018198; KEGG: cdl:CDR20291_1397 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase catalytic region; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase; ATP phosphoribosyltransferase 3366082..3366723 Spirochaeta smaragdinae DSM 11293 9491258 YP_003804834.1 CDS Spirs_3142 NC_014364.1 3366716 3367306 D COGs: COG0131 imidazoleglycerol-phosphate dehydratase; InterPro IPR000807:IPR020565; KEGG: msl:Msil_2554 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: imidazoleglycerol-phosphate dehydratase; SPTR: imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; imidazoleglycerol-phosphate dehydratase 3366716..3367306 Spirochaeta smaragdinae DSM 11293 9491259 YP_003804835.1 CDS Spirs_3143 NC_014364.1 3367408 3367719 D KEGG: tde:TDE2072 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3367408..3367719 Spirochaeta smaragdinae DSM 11293 9491260 YP_003804836.1 CDS Spirs_3144 NC_014364.1 3367716 3368870 D COGs: COG3063 Tfp pilus assembly protein PilF; InterPro IPR019734:IPR013026:IPR001440:IPR013105; KEGG: bdu:BDU_193 hypothetical protein; PFAM: hypothetical protein; TPR repeat-containing protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein 3367716..3368870 Spirochaeta smaragdinae DSM 11293 9491261 YP_003804837.1 CDS Spirs_3145 NC_014364.1 3368867 3369937 D COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR004383:IPR007197; KEGG: tde:TDE2074 radical SAM protein; PFAM: radical SAM domain protein; SPTR: ribosomal RNA large subunit methyltransferase N; TIGRFAM:radical SAM protein; PFAM: radical SAM superfamily; TIGRFAM:radical SAM protein; Cfr family radical SAM protein 3368867..3369937 Spirochaeta smaragdinae DSM 11293 9491262 YP_003804838.1 CDS Spirs_3146 NC_014364.1 3369890 3371683 R COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR018165:IPR018164:IPR012947:IPR002318; KEGG: tde:TDE1659 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc-like; threonyl/alanyl tRNA synthetase SAD; SPTR: Alanyl-tRNA synthetase; TIGRFAM: alanyl-tRNA synthetase; PFAM: threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanyl-tRNA synthetase; alanyl-tRNA synthetase complement(3369890..3371683) Spirochaeta smaragdinae DSM 11293 9491263 YP_003804839.1 CDS Spirs_3147 NC_014364.1 3371752 3372270 R InterPro IPR007829; KEGG: cyb:CYB_1204 TM2 domain-containing protein; PFAM: hypothetical protein; SPTR: TM2 domain protein; PFAM: TM2 domain; hypothetical protein complement(3371752..3372270) Spirochaeta smaragdinae DSM 11293 9491264 YP_003804840.1 CDS Spirs_3148 NC_014364.1 3372341 3373474 R COGs: COG1536 flagellar motor switch protein; InterPro IPR000090; KEGG: tle:Tlet_1899 flagellar motor switch protein G; PFAM: flagellar motor switch protein FliG; SPTR: flagellar motor switch protein FliG; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG; flagellar motor switch protein FliG complement(3372341..3373474) Spirochaeta smaragdinae DSM 11293 9491265 YP_003804841.1 CDS Spirs_3149 NC_014364.1 3373878 3374531 R COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: dol:Dole_2142 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; metallophosphoesterase complement(3373878..3374531) Spirochaeta smaragdinae DSM 11293 9491267 YP_003804842.1 CDS Spirs_3150 NC_014364.1 3374509 3375243 R COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: amt:Amet_1128 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(3374509..3375243) Spirochaeta smaragdinae DSM 11293 9491268 YP_003804843.1 CDS Spirs_3151 NC_014364.1 3375243 3375995 R COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: cbl:CLK_0812 ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3375243..3375995) Spirochaeta smaragdinae DSM 11293 9491269 YP_003804844.1 CDS Spirs_3152 NC_014364.1 3376029 3377033 R COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR015168; KEGG: amt:Amet_1129 sulfonate/nitrate transporter substrate-binding protein; PFAM: NMT1/THI5 like domain protein; SPTR: sulfonate/nitrate transporter substrate-binding protein; PFAM: NMT1/THI5 like; NMT1/THI5 like domain-containing protein complement(3376029..3377033) Spirochaeta smaragdinae DSM 11293 9491270 YP_003804845.1 CDS Spirs_3153 NC_014364.1 3377057 3378292 R COGs: COG0162 Tyrosyl-tRNA synthetase; InterPro IPR002942:IPR002307:IPR002305; KEGG: tde:TDE0861 tyrosyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; RNA-binding S4 domain protein; PRIAM: Tyrosine--tRNA ligase; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: tyrosyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase complement(3377057..3378292) Spirochaeta smaragdinae DSM 11293 9491271 YP_003804846.1 CDS Spirs_3154 NC_014364.1 3378294 3379625 R COGs: COG0423 glycyl-tRNA synthetase (class II); InterPro IPR006195:IPR002315:IPR002314:IPR004154; KEGG: tde:TDE0020 glycyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); anticodon-binding domain protein; SPTR: glycyl-tRNA synthetase; TIGRFAM: glycyl-tRNA synthetase; PFAM: anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: glycyl-tRNA synthetase, dimeric type; glycyl-tRNA synthetase complement(3378294..3379625) Spirochaeta smaragdinae DSM 11293 9491272 YP_003804847.1 CDS Spirs_3155 NC_014364.1 3379635 3381104 R COGs: COG0008 glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR020060:IPR020058:IPR004527; KEGG: bbz:BbuZS7_0374 glutamyl-tRNA synthetase; PFAM: glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; SPTR: glutamyl-tRNA synthetase; TIGRFAM: glutamyl-tRNA synthetase; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family; glutamyl-tRNA synthetase complement(3379635..3381104) Spirochaeta smaragdinae DSM 11293 9491273 YP_003804848.1 CDS Spirs_3156 NC_014364.1 3381184 3382011 R KEGG: tde:TDE1257 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3381184..3382011) Spirochaeta smaragdinae DSM 11293 9491274 YP_003804849.1 CDS Spirs_3157 NC_014364.1 3382081 3383238 D COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674:IPR006675; KEGG: tde:TDE1256 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase 3382081..3383238 Spirochaeta smaragdinae DSM 11293 9491275 YP_003804850.1 CDS Spirs_3158 NC_014364.1 3383296 3384447 D KEGG: sus:acid_6317 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3383296..3384447 Spirochaeta smaragdinae DSM 11293 9491276 YP_003804851.1 CDS Spirs_3159 NC_014364.1 3384475 3384666 D KEGG: tva:TVAG_094420 hypothetical protein; hypothetical protein 3384475..3384666 Spirochaeta smaragdinae DSM 11293 9491277 YP_003804852.1 CDS Spirs_3160 NC_014364.1 3384699 3386360 D COGs: COG0572 Uridine kinase; InterPro IPR003593; KEGG: tde:TDE2289 phosphoribulokinase/uridine kinase family protein; SMART: AAA ATPase; SPTR: Uridine kinase; PFAM: phosphoribulokinase / Uridine kinase family; ATPase AAA 3384699..3386360 Spirochaeta smaragdinae DSM 11293 9491278 YP_003804853.1 CDS Spirs_3161 NC_014364.1 3386374 3387261 D COGs: COG0679 permease; InterPro IPR004776:IPR017871; KEGG: jan:Jann_0431 hypothetical protein; PFAM: hypothetical protein; SPTR: Conserved hypothetical membrane protein, hypothetical protein family; PFAM: membrane transporter; hypothetical protein 3386374..3387261 Spirochaeta smaragdinae DSM 11293 9491279 YP_003804854.1 CDS Spirs_3162 NC_014364.1 3387221 3387349 R KEGG: scb:SCAB_28821 ATP synthase A chain; SPTR: Permease membrane component; hypothetical protein complement(3387221..3387349) Spirochaeta smaragdinae DSM 11293 9491280 YP_003804855.1 CDS Spirs_3163 NC_014364.1 3387346 3387720 R COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: cpi:Cpin_7289 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator complement(3387346..3387720) Spirochaeta smaragdinae DSM 11293 9491281 YP_003804856.1 CDS Spirs_3164 NC_014364.1 3387710 3388471 R KEGG: cpi:Cpin_7290 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3387710..3388471) Spirochaeta smaragdinae DSM 11293 9491282 YP_003804857.1 CDS Spirs_3165 NC_014364.1 3388471 3389313 R COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593:IPR003439; KEGG: dfe:Dfer_5189 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(3388471..3389313) Spirochaeta smaragdinae DSM 11293 9491283 YP_003804858.1 CDS Spirs_3166 NC_014364.1 3389395 3390063 R COGs: COG2360 Leu/Phe-tRNA-protein transferase; InterPro IPR004616; KEGG: afw:Anae109_0837 leucyl/phenylalanyl-tRNA--protein transferase; PFAM: leucyl/phenylalanyl-tRNA--protein transferase; PRIAM: leucyltransferase; SPTR: leucyl/phenylalanyl-tRNA--protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA/protein transferase; PFAM: leucyl/phenylalanyl-tRNA protein transferase; TIGRFAM: leucyl/phenylalanyl-tRNA--protein transferase; leucyl/phenylalanyl-tRNA/protein transferase complement(3389395..3390063) Spirochaeta smaragdinae DSM 11293 9491284 YP_003804859.1 CDS Spirs_3167 NC_014364.1 3390081 3392327 R COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003593:IPR001270:IPR004176:IPR003959:IPR 013093:IPR019489:IPR018368; KEGG: sat:SYN_02378 ATPase Clp protease ATP binding subunit; PFAM: ATPase AAA; ATPase AAA central domain protein; Clp domain protein; Clp ATPase-like; SMART: ATPase AAA; SPTR: ATPase clp protease ATP binding subunit; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent Clp protease ATP-binding subunit clpA; ATPase AAA complement(3390081..3392327) Spirochaeta smaragdinae DSM 11293 9491285 YP_003804860.1 CDS Spirs_3168 NC_014364.1 3392339 3392650 R COGs: COG2127 conserved hypothetical protein; InterPro IPR003769; KEGG: sdl:Sdel_1627 ATP-dependent Clp protease adaptor protein ClpS; PFAM: ATP-dependent Clp protease adaptor protein ClpS; SPTR: ATP-dependent Clp protease adaptor protein ClpS; manually curated; PFAM: ATP-dependent Clp protease adaptor protein ClpS; ATP-dependent Clp protease adaptor protein ClpS complement(3392339..3392650) Spirochaeta smaragdinae DSM 11293 9491286 YP_003804861.1 CDS Spirs_3169 NC_014364.1 3392643 3393254 R COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR002871:IPR007419; KEGG: paa:Paes_2001 nitrogen-fixing NifU domain protein; PFAM: nitrogen-fixing NifU domain protein; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: nitrogen-fixing NifU domain protein; PFAM: NifU-like N terminal domain; BFD-like [2Fe-2S] binding domain; nitrogen-fixing NifU domain-containing protein complement(3392643..3393254) Spirochaeta smaragdinae DSM 11293 9491287 YP_003804862.1 CDS Spirs_3170 NC_014364.1 3393251 3394429 R COGs: COG1104 cysteine sulfinate desulfinase/cysteine desulfurase; InterPro IPR016454:IPR000192:IPR020578; KEGG: dba:Dbac_0534 aminotransferase class V; PFAM: aminotransferase class V; PRIAM: cysteine desulfurase; SPTR: Aminotransferase class V; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase NifS; cysteine desulfurase complement(3393251..3394429) Spirochaeta smaragdinae DSM 11293 9491288 YP_003804863.1 CDS Spirs_3171 NC_014364.1 3394459 3394755 R COGs: COG2983 conserved hypothetical protein; InterPro IPR005358; KEGG: pca:Pcar_1310 hypothetical protein; PFAM: protein of unknown function UPF0153; SPTR: cytoplasmic protein; manually curated; hypothetical protein complement(3394459..3394755) Spirochaeta smaragdinae DSM 11293 9491289 YP_003804864.1 CDS Spirs_3172 NC_014364.1 3394755 3396827 R InterPro IPR013017:IPR001258; KEGG: tde:TDE2296 hypothetical protein; PFAM: NHL repeat containing protein; SPTR: uncharacterized protein; NHL repeat containing protein complement(3394755..3396827) Spirochaeta smaragdinae DSM 11293 9491290 YP_003804865.1 CDS Spirs_3173 NC_014364.1 3396824 3397507 R InterPro IPR019734:IPR013026:IPR001440; KEGG: tde:TDE2297 hypothetical protein; PFAM: hypothetical protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein complement(3396824..3397507) Spirochaeta smaragdinae DSM 11293 9491291 YP_003804866.1 CDS Spirs_3174 NC_014364.1 3397491 3398258 R COGs: COG0496 acid phosphatase; InterPro IPR002828; KEGG: gbm:Gbem_2685 stationary phase survival protein SurE; PFAM: Survival protein SurE; SPTR: 5'-nucleotidase surE; TIGRFAM: stationary-phase survival protein SurE; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE; stationary-phase survival protein SurE complement(3397491..3398258) Spirochaeta smaragdinae DSM 11293 9491292 YP_003804867.1 CDS Spirs_3175 NC_014364.1 3398277 3399434 R COGs: COG0153 Galactokinase; InterProIPR000705:IPR006206:IPR019539:IPR006204:IPR 013750:IPR006203; KEGG: tex:Teth514_1087 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase domain protein; SPTR: Galactokinase; TIGRFAM: galactokinase; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase; galactokinase complement(3398277..3399434) Spirochaeta smaragdinae DSM 11293 9491293 YP_003804868.1 CDS Spirs_3176 NC_014364.1 3399544 3401109 D COGs: COG0815 Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: tde:TDE2299 apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase 2; TIGRFAM: apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase 3399544..3401109 Spirochaeta smaragdinae DSM 11293 9491294 YP_003804869.1 CDS Spirs_3177 NC_014364.1 3401170 3402288 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 3401170..3402288 Spirochaeta smaragdinae DSM 11293 9491295 YP_003804870.1 CDS Spirs_3178 NC_014364.1 3402382 3402585 R COGs: COG0254 ribosomal protein L31; InterPro IPR002150; KEGG: tde:TDE1504 50S ribosomal protein L31; PFAM: ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: ribosomal protein L31; PFAM: ribosomal protein L31; TIGRFAM: ribosomal protein L31; 50S ribosomal protein L31 complement(3402382..3402585) Spirochaeta smaragdinae DSM 11293 9491296 YP_003804871.1 CDS Spirs_3179 NC_014364.1 3402663 3404243 R COGs: COG1158 transcription termination factor; InterProIPR011129:IPR003593:IPR011112:IPR011113:IPR 000194:IPR004665; KEGG: tpp:TPASS_0254 transcription termination factor Rho; PFAM: H+transporting two-sector ATPase alpha/subunit beta central region; Rho termination factor RNA-binding; Rho termination factor domain protein; SMART: Cold shock protein; ATPase AAA; SPTR: transcription termination factor Rho; TIGRFAM: transcription termination factor Rho; PFAM: Rho termination factor, N-terminal domain; Rho termination factor, RNA-binding domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: transcription termination factor Rho; transcription termination factor Rho complement(3402663..3404243) Spirochaeta smaragdinae DSM 11293 9491297 YP_003804872.1 CDS Spirs_3180 NC_014364.1 3404371 3405636 R COGs: COG1058 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; InterPro IPR008135:IPR001453:IPR008136; KEGG: tnp:Tnap_0500 competence/damage-inducible protein CinA; PFAM: damage inducible protein CinA; molybdopterin binding domain; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: competence/damage-inducible protein CinA; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain; competence/damage-inducible protein CinA complement(3404371..3405636) Spirochaeta smaragdinae DSM 11293 9491298 YP_003804873.1 CDS Spirs_3181 NC_014364.1 3405629 3406042 R COGs: COG1664 integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: lbl:LBL_0917 hypothetical protein; PFAM: protein of unknown function DUF583; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF583; hypothetical protein complement(3405629..3406042) Spirochaeta smaragdinae DSM 11293 9491299 YP_003804874.1 CDS Spirs_3182 NC_014364.1 3406079 3406300 R KEGG: lbf:LBF_2563 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3406079..3406300) Spirochaeta smaragdinae DSM 11293 9491300 YP_003804875.1 CDS Spirs_3183 NC_014364.1 3406302 3407039 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: ava:Ava_2150 response regulator receiver signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(3406302..3407039) Spirochaeta smaragdinae DSM 11293 9491301 YP_003804876.1 CDS Spirs_3184 NC_014364.1 3407111 3408754 R COGs: COG0815 Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: tde:TDE1708 apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase; TIGRFAM: apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase complement(3407111..3408754) Spirochaeta smaragdinae DSM 11293 9491302 YP_003804877.1 CDS Spirs_3185 NC_014364.1 3408763 3409116 R COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119:IPR020816; KEGG: bre:BRE_231 HbbU protein; PFAM: histone family protein DNA-binding protein; SMART: histone family protein DNA-binding protein; SPTR: HbbU protein; PFAM: Bacterial DNA-binding protein; histone family protein DNA-binding protein complement(3408763..3409116) Spirochaeta smaragdinae DSM 11293 9491303 YP_003804878.1 CDS Spirs_3186 NC_014364.1 3409118 3409387 R InterPro IPR002583; KEGG: ttr:Tter_0947 ribosomal protein S20; PFAM: ribosomal protein S20; SPTR: ribosomal protein S20; TIGRFAM: ribosomal protein S20; manually curated; PFAM: ribosomal protein S20; TIGRFAM: ribosomal protein S20; 30S ribosomal protein S20 complement(3409118..3409387) Spirochaeta smaragdinae DSM 11293 9491304 YP_003804879.1 CDS Spirs_3187 NC_014364.1 3409476 3410390 R COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: tde:TDE0113 tpl protein; PFAM: PSP1 domain protein; SPTR: Tpl protein; PFAM: PSP1 C-terminal conserved region; PSP1 domain-containing protein complement(3409476..3410390) Spirochaeta smaragdinae DSM 11293 9491305 YP_003804880.1 CDS Spirs_3188 NC_014364.1 3410406 3410912 R COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: btu:BT0244 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: protein of unknown function DUF327; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF327); hypothetical protein complement(3410406..3410912) Spirochaeta smaragdinae DSM 11293 9491306 YP_003804881.1 CDS Spirs_3189 NC_014364.1 3410900 3411373 R COGs: COG1664 integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: lbf:LBF_3355 hypothetical protein; PFAM: protein of unknown function DUF583; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF583; hypothetical protein complement(3410900..3411373) Spirochaeta smaragdinae DSM 11293 9491307 YP_003804882.1 CDS Spirs_3190 NC_014364.1 3411407 3412429 R COGs: COG0739 membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: tde:TDE0110 M23/M37 peptidase domain-containing protein; PFAM: peptidase M23; SPTR: M23/M37 peptidase domain protein; PFAM: peptidase family M23; peptidase M23 complement(3411407..3412429) Spirochaeta smaragdinae DSM 11293 9491308 YP_003804883.1 CDS Spirs_3191 NC_014364.1 3412590 3413363 D COGs: COG0084 Mg-dependent DNase; InterPro IPR012278:IPR001130:IPR015991:IPR000183; KEGG: tde:TDE2730 TatD family hydrolase; PFAM: TatD-related deoxyribonuclease; SPTR: Hydrolase, TatD family; TIGRFAM: hydrolase, TatD family; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family; hydrolase, TatD family 3412590..3413363 Spirochaeta smaragdinae DSM 11293 9491309 YP_003804884.1 CDS Spirs_3192 NC_014364.1 3413435 3414418 D COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR004652:IPR018517; KEGG: tde:TDE2731 NifR3 family TIM-barrel protein; PFAM: dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase B; TIGRFAM: hypothetical protein; PFAM: dihydrouridine synthase (Dus); TIGRFAM: hypothetical protein; hypothetical protein 3413435..3414418 Spirochaeta smaragdinae DSM 11293 9491310 YP_003804885.1 CDS Spirs_3193 NC_014364.1 3414555 3415811 D COGs: COG0151 phosphoribosylamine-glycine ligase; InterProIPR011761:IPR020562:IPR020561:IPR020560:IPR 000115:IPR020559; KEGG: eel:EUBELI_00551 phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, N-domain; phosphoribosylglycinamide synthetase, C-domain; PRIAM: phosphoribosylamine--glycine ligase; SPTR: phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase, N domain; phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase; phosphoribosylamine/glycine ligase 3414555..3415811 Spirochaeta smaragdinae DSM 11293 9491311 YP_003804886.1 CDS Spirs_3194 NC_014364.1 3415808 3416566 R COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: tde:TDE1443 RNA methyltransferase; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: SpoU rRNA methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, , group 3; TrmH family RNA methyltransferase complement(3415808..3416566) Spirochaeta smaragdinae DSM 11293 9491312 YP_003804887.1 CDS Spirs_3195 NC_014364.1 3416575 3417024 R KEGG: mxa:MXAN_3504 lipoprotein; SPTR: lipoprotein; hypothetical protein complement(3416575..3417024) Spirochaeta smaragdinae DSM 11293 9491313 YP_003804888.1 CDS Spirs_3196 NC_014364.1 3417079 3417687 R KEGG: mgr:MGG_11115 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3417079..3417687) Spirochaeta smaragdinae DSM 11293 9491314 YP_003804889.1 CDS Spirs_3197 NC_014364.1 3417647 3418780 R COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterProIPR001623:IPR001305:IPR003095:IPR002939:IPR 012724:IPR018253; KEGG: tde:TDE0629 chaperone protein DnaJ; PFAM: chaperone DnaJ domain protein; heat shock protein DnaJ domain protein; DnaJ central domain protein; SMART: heat shock protein DnaJ domain protein; SPTR: Chaperone protein dnaJ; TIGRFAM: chaperone protein DnaJ; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ; chaperone protein DnaJ complement(3417647..3418780) Spirochaeta smaragdinae DSM 11293 9491315 YP_003804890.1 CDS Spirs_3198 NC_014364.1 3418797 3420746 R COGs: COG0443 Molecular chaperone; InterPro IPR012725:IPR001023:IPR013126:IPR018181; KEGG: tde:TDE0628 molecular chaperone DnaK; PFAM: heat shock protein 70; SPTR: Chaperone protein DnaK; TIGRFAM: chaperone protein DnaK; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK; chaperone protein DnaK complement(3418797..3420746) Spirochaeta smaragdinae DSM 11293 9491316 YP_003804891.1 CDS Spirs_3199 NC_014364.1 3420808 3421491 R COGs: COG0576 Molecular chaperone GrpE (heat shock protein); InterPro IPR000740; KEGG: tde:TDE0627 co-chaperone protein GrpE; PFAM: GrpE protein; SPTR: protein grpE; PFAM: GrpE; GrpE protein complement(3420808..3421491) Spirochaeta smaragdinae DSM 11293 9491317 YP_003804892.1 CDS Spirs_3200 NC_014364.1 3421626 3425018 R KEGG: tde:TDE2293 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3421626..3425018) Spirochaeta smaragdinae DSM 11293 9491318 YP_003804893.1 CDS Spirs_3201 NC_014364.1 3425070 3425735 R COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834; KEGG: bre:BRE_516 hydrolase; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: hydrolase; PFAM: haloacid dehalogenase-like hydrolase; haloacid dehalogenase complement(3425070..3425735) Spirochaeta smaragdinae DSM 11293 9491319 YP_003804894.1 CDS Spirs_3202 NC_014364.1 3425759 3426760 R KEGG: prw:PsycPRwf_1514 TonB family protein; SPTR: TonB family protein; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain; hypothetical protein complement(3425759..3426760) Spirochaeta smaragdinae DSM 11293 9491320 YP_003804895.1 CDS Spirs_3203 NC_014364.1 3426760 3427164 R COGs: COG0848 biopolymertransporter; InterPro IPR003400; KEGG: pca:Pcar_1506 biopolymer transporter; PFAM: Biopolymer transporter ExbD/TolR; SPTR: biopolymertransporter; PFAM: biopolymertransporter ExbD/TolR; biopolymertransporter ExbD/TolR complement(3426760..3427164) Spirochaeta smaragdinae DSM 11293 9491321 YP_003804896.1 CDS Spirs_3204 NC_014364.1 3427161 3427778 R COGs: COG0811 biopolymertransporter; InterPro IPR002898; KEGG: bhy:BHWA1_00538 biopolymer transporter ExbB; PFAM: MotA/TolQ/ExbB proton channel; SPTR: biopolymertransporter ExbB; PFAM: MotA/TolQ/ExbB proton channel family; MotA/TolQ/ExbB proton channel complement(3427161..3427778) Spirochaeta smaragdinae DSM 11293 9491322 YP_003804897.1 CDS Spirs_3205 NC_014364.1 3427794 3429392 R KEGG: rsh:Rsph17029_3404 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3427794..3429392) Spirochaeta smaragdinae DSM 11293 9491323 YP_003804898.1 CDS Spirs_3206 NC_014364.1 3429389 3432277 R InterProIPR019734:IPR006597:IPR013026:IPR001440:IPR 011717; KEGG: rmr:Rmar_1517 outer membrane assembly lipoprotein YfiO; PFAM: TPR repeat-containing protein; Sel1 domain protein repeat-containing protein; hypothetical protein; SPTR: Outer membrane assembly lipoprotein YfiO; hypothetical protein complement(3429389..3432277) Spirochaeta smaragdinae DSM 11293 9491324 YP_003804899.1 CDS Spirs_3207 NC_014364.1 3432280 3433620 R KEGG: tde:TDE1533 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3432280..3433620) Spirochaeta smaragdinae DSM 11293 9491325 YP_003804900.1 CDS Spirs_3208 NC_014364.1 3433617 3433982 R InterPro IPR000551; KEGG: tde:TDE0082 MerR family transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: MerR family transcriptional regulator; PFAM: MerR family regulatory protein; MerR family transcriptional regulator complement(3433617..3433982) Spirochaeta smaragdinae DSM 11293 9491326 YP_003804901.1 CDS Spirs_3209 NC_014364.1 3434014 3435375 R COGs: COG1160 GTPase; InterPro IPR016484:IPR006073:IPR002917:IPR005225; KEGG: tde:TDE0083 GTP-binding protein EngA; PFAM: GTP-binding protein HSR1-related; SPTR: GTP-binding protein engA; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain; ribosome-associated GTPase EngA complement(3434014..3435375) Spirochaeta smaragdinae DSM 11293 9491327 YP_003804902.1 CDS Spirs_3210 NC_014364.1 3435347 3437092 R COGs: COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component); InterProIPR006318:IPR008731:IPR008279:IPR000121:IPR 018274; KEGG: tte:TTE2334 phosphoenolpyruvate-protein kinase; PFAM: PEP-utilizing protein; PEP-utilising protein domain protein; PEP-utilising protein mobile region; SPTR: phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria); TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; phosphoenolpyruvate-protein phosphotransferase complement(3435347..3437092) Spirochaeta smaragdinae DSM 11293 9491328 YP_003804903.1 CDS Spirs_3211 NC_014364.1 3437166 3437939 D COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: tde:TDE2081 hypothetical protein; PFAM: Lipoprotein LpqB, GerMN domain; SPTR: uncharacterized protein; PFAM: sporulation and spore germination; Lipoprotein LpqB, GerMN domain-containing protein 3437166..3437939 Spirochaeta smaragdinae DSM 11293 9491329 YP_003804904.1 CDS Spirs_3212 NC_014364.1 3437932 3438708 R COGs: COG1189 rRNA methylase; InterPro IPR002877; KEGG: tro:trd_0802 hemolysin A; PFAM: ribosomal RNA methyltransferase RrmJ/FtsJ; SPTR: Hemolysin A; PFAM: FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein; ribosomal RNA methyltransferase RrmJ/FtsJ complement(3437932..3438708) Spirochaeta smaragdinae DSM 11293 9491330 YP_003804905.1 CDS Spirs_3213 NC_014364.1 3438718 3439512 R COGs: COG1692 conserved hypothetical protein; InterPro IPR005235; KEGG: gsu:GSU1138 Ser/Thr protein phosphatase family protein; SPTR: Ser/Thr protein phosphatase family protein; TIGRFAM: conserved hypothetical protein TIGR00282; Ser/Thr protein phosphatase family protein complement(3438718..3439512) Spirochaeta smaragdinae DSM 11293 9491331 YP_003804906.1 CDS Spirs_3214 NC_014364.1 3439502 3441031 R COGs: COG1418 HD superfamily hydrolase; InterProIPR004087:IPR003607:IPR004088:IPR018111:IPR 006674:IPR017705:IPR006675; KEGG: tde:TDE0237 hypothetical protein; PFAM: metal-dependent phosphohydrolase HD sub domain; K Homology, type 1, subgroup; SMART: metal-dependent phosphohydrolase HD region; KH domain protein; SPTR: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; TIGRFAM: YmdA/YtgF protein; metal dependent phophohydrolase; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG; metal dependent phosphohydrolase complement(3439502..3441031) Spirochaeta smaragdinae DSM 11293 9491332 YP_003804907.1 CDS Spirs_3215 NC_014364.1 3441091 3444795 R KEGG: tde:TDE2611 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3441091..3444795) Spirochaeta smaragdinae DSM 11293 9491333 YP_003804908.1 CDS Spirs_3216 NC_014364.1 3444856 3445152 R KEGG: bba:Bd1920 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3444856..3445152) Spirochaeta smaragdinae DSM 11293 9491334 YP_003804909.1 CDS Spirs_3217 NC_014364.1 3445263 3446021 R COGs: COG0289 dihydrodipicolinate reductase; InterPro IPR000846:IPR011770; KEGG: tpd:Teth39_1503 dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase; PRIAM: dihydrodipicolinate reductase; SPTR: uncharacterized protein; TIGRFAM: dihydrodipicolinate reductase; PFAM: dihydrodipicolinate reductase, N-terminus; dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase; dihydrodipicolinate reductase complement(3445263..3446021) Spirochaeta smaragdinae DSM 11293 9491335 YP_003804910.1 CDS Spirs_3218 NC_014364.1 3446363 3448126 R COGs: COG2103 sugar phosphate isomerase; KEGG: ptm:GSPATT00019053001 hypothetical protein; SPTR: Sugar phosphate isomerase-like protein; sugar phosphate isomerase complement(3446363..3448126) Spirochaeta smaragdinae DSM 11293 9491336 YP_003804911.1 CDS Spirs_3219 NC_014364.1 3448128 3448760 R COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005833:IPR005834:IPR006402:IPR019793; KEGG: tle:Tlet_2032 HAD family hydrolase; PFAM: haloacid dehalogenase; SPTR: HAD-superfamily hydrolase, subfamily IA, variant 3; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; Epoxide hydrolase N-terminal domain-like phosphatase; HAD-superfamily hydrolase complement(3448128..3448760) Spirochaeta smaragdinae DSM 11293 9491337 YP_003804912.1 CDS Spirs_3220 NC_014364.1 3448772 3449629 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tle:Tlet_0131 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3448772..3449629) Spirochaeta smaragdinae DSM 11293 9491338 YP_003804913.1 CDS Spirs_3221 NC_014364.1 3449642 3450541 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tle:Tlet_0132 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3449642..3450541) Spirochaeta smaragdinae DSM 11293 9491339 YP_003804914.1 CDS Spirs_3222 NC_014364.1 3450612 3451922 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: tle:Tlet_0133 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3450612..3451922) Spirochaeta smaragdinae DSM 11293 9491340 YP_003804915.1 CDS Spirs_3223 NC_014364.1 3452030 3453091 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: cwo:Cwoe_1260 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; MarR family; ROK family protein complement(3452030..3453091) Spirochaeta smaragdinae DSM 11293 9491341 YP_003804916.1 CDS Spirs_3224 NC_014364.1 3458560 3460695 R COGs: COG0438 glycosyltransferase; InterPro IPR013200:IPR001296:IPR006379; KEGG: dat:HRM2_48150 hydrolase (HAD superfamily protein); PFAM: glycosyl transferase group 1; Haloacid dehalogenase domain protein hydrolase type 3; SPTR: hydrolase (HAD superfamily protein); TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; PFAM: glycosyl transferases group 1; haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; HAD-superfamily hydrolase complement(3458560..3460695) Spirochaeta smaragdinae DSM 11293 9491346 YP_003804917.1 CDS Spirs_3225 NC_014364.1 3460715 3461311 R COGs: COG0558 phosphatidylglycerophosphate synthase; InterPro IPR004570:IPR000462; KEGG: bhr:BH0721 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; manually curated; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; CDP-diacylglycerol/glycerol-3-phosphate3- phosphatidyltransferase complement(3460715..3461311) Spirochaeta smaragdinae DSM 11293 9491347 YP_003804918.1 CDS Spirs_3226 NC_014364.1 3461364 3461651 R KEGG: rle:pRL120564 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3461364..3461651) Spirochaeta smaragdinae DSM 11293 9491348 YP_003804919.1 CDS Spirs_3227 NC_014364.1 3461656 3462417 R KEGG: app:CAP2UW1_2674 ferric reductase domain protein protein transmembrane component domain protein; SPTR: ferric reductase domain protein protein transmembrane component domain protein; hypothetical protein complement(3461656..3462417) Spirochaeta smaragdinae DSM 11293 9491349 YP_003804920.1 CDS Spirs_3228 NC_014364.1 3462407 3463885 R COGs: COG2317 Zn-dependent carboxypeptidase; InterPro IPR001333; KEGG: srm:SRM_02702 thermostable carboxypeptidase 1; PFAM: peptidase M32 carboxypeptidase Taq metallopeptidase; PRIAM: carboxypeptidase Taq; SPTR: carboxypeptidase; PFAM: carboxypeptidase Taq (M32) metallopeptidase; carboxypeptidase Taq complement(3462407..3463885) Spirochaeta smaragdinae DSM 11293 9491350 YP_003804921.1 CDS Spirs_3229 NC_014364.1 3463882 3465639 R COGs: COG0441 threonyl-tRNA synthetase; InterProIPR006195:IPR018158:IPR012947:IPR002314:IPR 004154:IPR002320; KEGG: btu:BT0720 threonyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); threonyl/alanyl tRNA synthetase SAD; anticodon-binding domain protein; SPTR: threonyl-tRNA synthetase; TIGRFAM: threonyl-tRNA synthetase; PFAM: anticodon binding domain; threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase; threonyl-tRNA synthetase complement(3463882..3465639) Spirochaeta smaragdinae DSM 11293 9491351 YP_003804922.1 CDS Spirs_3230 NC_014364.1 3466015 3466815 R COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: nhl:Nhal_1224 alpha/beta hydrolase fold protein; PFAM: alpha/beta hydrolase fold; SPTR: Hydrolase, alpha/beta fold family, ; PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein complement(3466015..3466815) Spirochaeta smaragdinae DSM 11293 9491352 YP_003804923.1 CDS Spirs_3231 NC_014364.1 3466812 3467198 R KEGG: saj:SaurJH9_0851 hypothetical protein; SPTR: Phage protein; hypothetical protein complement(3466812..3467198) Spirochaeta smaragdinae DSM 11293 9491353 YP_003804924.1 CDS Spirs_3232 NC_014364.1 3467311 3468129 D COGs: COG1794 aspartate racemase; InterPro IPR015942; KEGG: rmr:Rmar_2418 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: aspartate racemase; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase; Asp/Glu/hydantoin racemase 3467311..3468129 Spirochaeta smaragdinae DSM 11293 9491354 YP_003804925.1 CDS Spirs_3233 NC_014364.1 3468169 3468978 R COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR005834:IPR006357; KEGG: afn:Acfer_1456 HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: Haloacid dehalogenase-like hydrolase, ; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; Haloacid Dehalogenase Superfamily class (subfamily) IIA; HAD-superfamily hydrolase complement(3468169..3468978) Spirochaeta smaragdinae DSM 11293 9491355 YP_003804926.1 CDS Spirs_3234 NC_014364.1 3468971 3469534 R COGs: COG0778 nitroreductase; InterPro IPR000415; KEGG: trq:TRQ2_0551 nitroreductase; PFAM: nitroreductase; SPTR: Bacterioferritin comigratory protein/NADH dehydrogenase; PFAM: nitroreductase family; nitroreductase complement(3468971..3469534) Spirochaeta smaragdinae DSM 11293 9491356 YP_003804927.1 CDS Spirs_3235 NC_014364.1 3469547 3470398 R COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: cpy:Cphy_2449 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: hydroxymethylbutenyl pyrophosphate reductase; TIGRFAM: hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming); hydroxymethylbutenyl pyrophosphate reductase complement(3469547..3470398) Spirochaeta smaragdinae DSM 11293 9491357 YP_003804928.1 CDS Spirs_3236 NC_014364.1 3470454 3471809 R COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR003335:IPR005665; KEGG: tde:TDE0680 preprotein translocase subunit SecF; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: protein-export membrane protein SecF; TIGRFAM: protein-export membrane protein SecF; protein-export membrane protein, SecD/SecF family; PFAM: protein export membrane protein; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF; protein-export membrane protein SecF complement(3470454..3471809) Spirochaeta smaragdinae DSM 11293 9491358 YP_003804929.1 CDS Spirs_3237 NC_014364.1 3471806 3473533 R COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR003335:IPR005791; KEGG: tde:TDE0681 preprotein translocase subunit SecD; PFAM: SecD/SecF/SecDF export membrane protein; SPTR: protein-export membrane protein SecD; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; PFAM: protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecD complement(3471806..3473533) Spirochaeta smaragdinae DSM 11293 9491359 YP_003804930.1 CDS Spirs_3238 NC_014364.1 3473579 3473947 R COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: gym:GYMC10_1563 preprotein translocase, YajC subunit; PFAM: YajC family protein; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: preprotein translocase, YajC subunit; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit; preprotein translocase subunit YajC complement(3473579..3473947) Spirochaeta smaragdinae DSM 11293 9491360 YP_003804931.1 CDS Spirs_3239 NC_014364.1 3474027 3474320 R KEGG: bbz:BbuZS7_0670 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3474027..3474320) Spirochaeta smaragdinae DSM 11293 9491361 YP_003804932.1 CDS Spirs_3240 NC_014364.1 3474437 3476098 R COGs: COG0459 chaperonin GroEL (HSP60 family); InterPro IPR001844:IPR002423:IPR018370; KEGG: tde:TDE1175 chaperonin GroEL; PFAM: chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: chaperonin GroEL; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL; chaperonin GroEL complement(3474437..3476098) Spirochaeta smaragdinae DSM 11293 9491362 YP_003804933.1 CDS Spirs_3241 NC_014364.1 3476235 3476819 R COGs: COG2316 hydrolase (HD superfamily); InterPro IPR006675; KEGG: gbm:Gbem_0692 metal dependent phophohydrolase; SPTR: metal dependent phophohydrolase; TIGRFAM: metal dependent phophohydrolase; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase complement(3476235..3476819) Spirochaeta smaragdinae DSM 11293 9491363 YP_003804934.1 CDS Spirs_3242 NC_014364.1 3476942 3477742 R COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR004143:IPR004408:IPR018357; KEGG: pph:Ppha_2840 biotin/acetyl-CoA-carboxylase ligase; PFAM: biotin/lipoate A/B protein ligase; SPTR: Biotin-[acetyl-CoA-carboxylase] ligase; TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; biotin/acetyl-CoA-carboxylase ligase complement(3476942..3477742) Spirochaeta smaragdinae DSM 11293 9491364 YP_003804935.1 CDS Spirs_3243 NC_014364.1 3477897 3478367 D COGs: COG1438 Arginine repressor; InterPro IPR001669; KEGG: argR; arginine repressor; PFAM: arginine repressor; SPTR: Arginine repressor; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor; arginine repressor ArgR 3477897..3478367 Spirochaeta smaragdinae DSM 11293 9491365 YP_003804936.1 CDS Spirs_3244 NC_014364.1 3478487 3479758 D COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518:IPR018223; KEGG: sti:Sthe_3259 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; argininosuccinate synthase 3478487..3479758 Spirochaeta smaragdinae DSM 11293 9491366 YP_003804937.1 CDS Spirs_3245 NC_014364.1 3479879 3481462 D COGs: COG0166 glucose-6-phosphate isomerase; InterPro IPR001672:IPR018189; KEGG: eel:EUBELI_00049 glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase (PGI); SPTR: glucose-6-phosphate isomerase; PFAM: phosphoglucose isomerase; phosphoglucose isomerase (PGI) 3479879..3481462 Spirochaeta smaragdinae DSM 11293 9491367 YP_003804938.1 CDS Spirs_3246 NC_014364.1 3481953 3484130 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: bhy:BHWA1_01729 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 3481953..3484130 Spirochaeta smaragdinae DSM 11293 9491368 YP_003804939.1 CDS Spirs_3247 NC_014364.1 3484210 3485580 R COGs: COG0205 6-phosphofructokinase; InterPro IPR012004:IPR000023; KEGG: tpp:TPASS_0108 diphosphate--fructose-6-phosphate 1-phosphotransferase; PFAM: phosphofructokinase; SPTR: Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (Pfk); PFAM: phosphofructokinase; phosphofructokinase complement(3484210..3485580) Spirochaeta smaragdinae DSM 11293 9491369 YP_003804940.1 CDS Spirs_3248 NC_014364.1 3485703 3485864 D hypothetical protein 3485703..3485864 Spirochaeta smaragdinae DSM 11293 9491370 YP_003804941.1 CDS Spirs_3249 NC_014364.1 3485867 3488371 D COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000014:IPR000160:IPR001633:IPR013767; KEGG: npu:Npun_R1505 diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); PFAM: EAL domain protein; GGDEF domain containing protein; PAS fold domain protein; SMART: EAL domain protein; GGDEF domain containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S); TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase 3485867..3488371 Spirochaeta smaragdinae DSM 11293 9491371 YP_003804942.1 CDS Spirs_3250 NC_014364.1 3488453 3489622 D COGs: COG0624 acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylase; InterPro IPR011650:IPR001261; KEGG: caa:Caka_1158 hypothetical protein; PFAM: peptidase dimerisation domain protein; SPTR: uncharacterized protein; PFAM: peptidase dimerisation domain; peptidase dimerization domain-containing protein 3488453..3489622 Spirochaeta smaragdinae DSM 11293 9491372 YP_003804943.1 CDS Spirs_3251 NC_014364.1 3489612 3490598 D InterPro IPR001173; KEGG: caa:Caka_1159 glycosyl transferase family 2; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase 3489612..3490598 Spirochaeta smaragdinae DSM 11293 9491373 YP_003804944.1 CDS Spirs_3252 NC_014364.1 3490595 3490948 D KEGG: pmx:PERMA_1751 conserved protein YrvD; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1049); hypothetical protein 3490595..3490948 Spirochaeta smaragdinae DSM 11293 9491374 YP_003804945.1 CDS Spirs_3253 NC_014364.1 3490960 3491406 D COGs: COG1963 conserved hypothetical protein; InterPro IPR003832; KEGG: mrb:Mrub_2370 acid phosphatase/vanadium-dependent haloperoxidase-like protein; PFAM: acid phosphatase/vanadium-dependent haloperoxidase related; SPTR: acid phosphatase/vanadium-dependent haloperoxidase related protein; PFAM: Divergent PAP2 family; acid phosphatase/vanadium-dependent haloperoxidase-like protein 3490960..3491406 Spirochaeta smaragdinae DSM 11293 9491375 YP_003804946.1 CDS Spirs_3254 NC_014364.1 3491414 3493693 R InterPro IPR011701; KEGG: tde:TDE0707 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: transporter major facilitator family; major facilitator superfamily protein complement(3491414..3493693) Spirochaeta smaragdinae DSM 11293 9491376 YP_003804947.1 CDS Spirs_3255 NC_014364.1 3493737 3495656 R COGs: COG1166 Arginine decarboxylase (spermidine biosynthesis); InterPro IPR002985:IPR000183; KEGG: cce:Ccel_1119 arginine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; SPTR: Arginine decarboxylase; TIGRFAM: arginine decarboxylase; PFAM: pyridoxal-dependent decarboxylase, C-terminal sheet domain; pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: arginine decarboxylase, biosynthetic; arginine decarboxylase complement(3493737..3495656) Spirochaeta smaragdinae DSM 11293 9491377 YP_003804948.1 CDS Spirs_3256 NC_014364.1 3495691 3496032 R COGs: COG3695 methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: dde:Dde_3099 methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding; SPTR: methylated-DNA--protein-cysteine methyltransferase; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase; methylated-DNA-(protein)-cysteine S-methyltransferase DNA binding protein complement(3495691..3496032) Spirochaeta smaragdinae DSM 11293 9491378 YP_003804949.1 CDS Spirs_3257 NC_014364.1 3496029 3497339 R COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR017896:IPR001395:IPR017900; KEGG: mmh:Mmah_0761 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: protein with aldo/keto reductase domain; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(3496029..3497339) Spirochaeta smaragdinae DSM 11293 9491379 YP_003804950.1 CDS Spirs_3258 NC_014364.1 3497674 3498375 R COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: cce:Ccel_1263 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(3497674..3498375) Spirochaeta smaragdinae DSM 11293 9491381 YP_003804951.1 CDS Spirs_3259 NC_014364.1 3498824 3500011 D COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342:IPR018110; KEGG: dsy:DSY1349 hypothetical protein; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: uncharacterized protein; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; mandelate racemase / muconate lactonizing enzyme, N-terminal domain; mandelate racemase/muconate lactonizing protein 3498824..3500011 Spirochaeta smaragdinae DSM 11293 9491382 YP_003804952.1 CDS Spirs_3260 NC_014364.1 3500041 3501342 D COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: cpf:CPF_0425 major facilitator family protein; PFAM: major facilitator superfamily MFS_1; SPTR: uncharacterized protein; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 3500041..3501342 Spirochaeta smaragdinae DSM 11293 9491383 YP_003804953.1 CDS Spirs_3261 NC_014364.1 3501368 3502792 D COGs: COG1288 membrane protein; InterPro IPR018385; KEGG: pcr:Pcryo_0766 C4-dicarboxylate anaerobic carrier; PFAM: C4-dicarboxylate anaerobic carrier-like; SPTR: C4-dicarboxylate anaerobic carrier; PFAM: C4-dicarboxylate anaerobic carrier; C4-dicarboxylate anaerobic carrier 3501368..3502792 Spirochaeta smaragdinae DSM 11293 9491384 YP_003804954.1 CDS Spirs_3262 NC_014364.1 3502950 3504953 R COGs: COG1501 alpha-glucosidase family 31 of glycosyl hydrolase; InterPro IPR000322; KEGG: cbe:Cbei_2891 glycoside hydrolase family protein; PFAM: glycoside hydrolase family 31; SPTR: glycoside hydrolase, family 31; PFAM: glycosyl hydrolases family 31; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; glycoside hydrolase family protein complement(3502950..3504953) Spirochaeta smaragdinae DSM 11293 9491385 YP_003804955.1 CDS Spirs_3263 NC_014364.1 3504980 3505816 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: cbe:Cbei_2892 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3504980..3505816) Spirochaeta smaragdinae DSM 11293 9491386 YP_003804956.1 CDS Spirs_3264 NC_014364.1 3505813 3506751 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: cbe:Cbei_2893 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3505813..3506751) Spirochaeta smaragdinae DSM 11293 9491387 YP_003804957.1 CDS Spirs_3265 NC_014364.1 3506794 3508032 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cbe:Cbei_2894 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3506794..3508032) Spirochaeta smaragdinae DSM 11293 9491388 YP_003804958.1 CDS Spirs_3266 NC_014364.1 3508154 3509683 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005; KEGG: cbe:Cbei_2897 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: uncharacterized protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(3508154..3509683) Spirochaeta smaragdinae DSM 11293 9491389 YP_003804959.1 CDS Spirs_3267 NC_014364.1 3509691 3511538 R COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594; KEGG: cbe:Cbei_2898 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(3509691..3511538) Spirochaeta smaragdinae DSM 11293 9491390 YP_003804960.1 CDS Spirs_3268 NC_014364.1 3511710 3513650 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR003439:IPR017940:IPR001140:IPR 017871; KEGG: dhd:Dhaf_2246 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC-type multidrug transporter, ATPase and permeases; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3511710..3513650) Spirochaeta smaragdinae DSM 11293 9491391 YP_003804961.1 CDS Spirs_3269 NC_014364.1 3513643 3515394 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR003439:IPR017940:IPR001140:IPR 017871; KEGG: dhd:Dhaf_2245 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3513643..3515394) Spirochaeta smaragdinae DSM 11293 9491392 YP_003804962.1 CDS Spirs_3270 NC_014364.1 3515439 3515882 R InterPro IPR000835; KEGG: dhd:Dhaf_2244 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator complement(3515439..3515882) Spirochaeta smaragdinae DSM 11293 9491393 YP_003804963.1 CDS Spirs_3271 NC_014364.1 3516065 3516733 R InterPro IPR018649; KEGG: afe:Lferr_0168 hypothetical protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078); hypothetical protein complement(3516065..3516733) Spirochaeta smaragdinae DSM 11293 9491394 YP_003804964.1 CDS Spirs_3272 NC_014364.1 3516757 3517023 R InterPro IPR018649; KEGG: afr:AFE_1333 hypothetical protein; PFAM: protein of unknown function DUF2078, membrane; SPTR: uncharacterized protein; PFAM: Predicted membrane protein (DUF2078); hypothetical protein complement(3516757..3517023) Spirochaeta smaragdinae DSM 11293 9491395 YP_003804965.1 CDS Spirs_3273 NC_014364.1 3517035 3519020 R COGs: COG2217 Cation transport ATPase; InterProIPR001757:IPR000695:IPR008250:IPR005834:IPR 006403:IPR006416:IPR018303; KEGG: copper-transporting ATPase, P-type (CopB); PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Copper-transporting ATPase, P-type (CopB); TIGRFAM: copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase complement(3517035..3519020) Spirochaeta smaragdinae DSM 11293 9491396 YP_003804966.1 CDS Spirs_3274 NC_014364.1 3519166 3519447 D KEGG: rbo:A1I_05800 NADH dehydrogenase subunit E; SPTR: uncharacterized protein; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit; hypothetical protein 3519166..3519447 Spirochaeta smaragdinae DSM 11293 9491397 YP_003804967.1 CDS Spirs_3275 NC_014364.1 3519450 3520964 D COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR017896:IPR001450:IPR004108:IPR017900; KEGG: apr:Apre_1371 hydrogenase large subunit domain protein; PFAM: hydrogenase large subunit domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; 4Fe-4S binding domain; hydrogenase large subunit domain-containing protein 3519450..3520964 Spirochaeta smaragdinae DSM 11293 9491398 YP_003804968.1 CDS Spirs_3276 NC_014364.1 3520970 3523987 R COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR003660:IPR006674; KEGG: mag:amb3625 methyl-accepting chemotaxis protein; PFAM: histidine kinase HAMP region domain protein; metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: methyl-accepting chemotaxis protein; metal dependent phosphohydrolase complement(3520970..3523987) Spirochaeta smaragdinae DSM 11293 9491399 YP_003804969.1 CDS Spirs_3277 NC_014364.1 3524122 3524724 R COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: vha:VIBHAR_04752 aldolase; PFAM: class II aldolase/adducin family protein; SPTR: class II aldolase/adducin N-terminal domain-containing protein; PFAM: class II Aldolase and Adducin N-terminal domain; class II aldolase/adducin family protein complement(3524122..3524724) Spirochaeta smaragdinae DSM 11293 9491400 YP_003804970.1 CDS Spirs_3278 NC_014364.1 3524744 3526018 R COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: bmr:BMI_II146 hypothetical protein; PFAM: type III effector Hrp-dependent outers; SPTR: uncharacterized protein; PFAM: protein of unknown function, DUF1537; type III effector Hrp-dependent outer protein complement(3524744..3526018) Spirochaeta smaragdinae DSM 11293 9491401 YP_003804971.1 CDS Spirs_3279 NC_014364.1 3526057 3526344 R InterPro IPR007138; KEGG: rde:RD1_3790 hypothetical protein; PFAM: antibiotic biosynthesis monooxygenase; SPTR: uncharacterized protein; PFAM: antibiotic biosynthesis monooxygenase; antibiotic biosynthesis monooxygenase complement(3526057..3526344) Spirochaeta smaragdinae DSM 11293 9491402 YP_003804972.1 CDS Spirs_3280 NC_014364.1 3526347 3527435 R COGs: COG0473 isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804; KEGG: bbt:BBta_2804 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase; 3-isopropylmalate dehydrogenase complement(3526347..3527435) Spirochaeta smaragdinae DSM 11293 9491403 YP_003804973.1 CDS Spirs_3281 NC_014364.1 3527457 3528734 R COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR010656:IPR004681; KEGG: aco:Amico_0090 TRAP dicarboxylate transporter DctM subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: TRAP dicarboxylate transporter DctM subunit; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM complement(3527457..3528734) Spirochaeta smaragdinae DSM 11293 9491404 YP_003804974.1 CDS Spirs_3282 NC_014364.1 3528731 3529273 R COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: apr:Apre_1612 tripartite ATP-independent periplasmic transporter DctQ component; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: tripartite ATP-independent periplasmic transporter DctQ component; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ component complement(3528731..3529273) Spirochaeta smaragdinae DSM 11293 9491405 YP_003804975.1 CDS Spirs_3283 NC_014364.1 3529330 3530340 R COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389:IPR004682; KEGG: aco:Amico_0088 TRAP dicarboxylate transporter DctP subunit; PFAM: extracellular solute-binding protein, family 7; SPTR: uncharacterized protein; TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP complement(3529330..3530340) Spirochaeta smaragdinae DSM 11293 9491406 YP_003804976.1 CDS Spirs_3284 NC_014364.1 3530673 3531401 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: dds:Ddes_0854 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator NanR; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 3530673..3531401 Spirochaeta smaragdinae DSM 11293 9491407 YP_003804977.1 CDS Spirs_3285 NC_014364.1 3531396 3531932 R InterPro IPR003339; KEGG: tko:TK0745 ABC-type cobalt transporter, permease; PFAM: cobalt transporter; SPTR: Cobalt transporter; PFAM: Cobalt transporter; cobalt transporter complement(3531396..3531932) Spirochaeta smaragdinae DSM 11293 9491408 YP_003804978.1 CDS Spirs_3288 NC_014364.1 3532627 3533778 R COGs: COG0075 serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: mlo:mlr6806 aspartate aminotransferase; PFAM: aminotransferase class V; PRIAM: serine--pyruvate transaminase; SPTR: aspartate aminotransferase; PFAM: Aminotransferase class-V; serine--pyruvate transaminase complement(3532627..3533778) Spirochaeta smaragdinae DSM 11293 9491411 YP_003804979.1 CDS Spirs_3289 NC_014364.1 3534029 3534844 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089:IPR004090; KEGG: tte:TTE0680 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis protein; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(3534029..3534844) Spirochaeta smaragdinae DSM 11293 9491412 YP_003804980.1 CDS Spirs_3290 NC_014364.1 3534850 3535959 R COGs: COG3287 conserved hypothetical protein; InterPro IPR013702:IPR019494; KEGG: ppd:Ppro_3141 hypothetical protein; PFAM: domain of unknown function DUF1745; FIST C domain; SPTR: uncharacterized protein; PFAM: FIST C domain; FIST N domain; hypothetical protein complement(3534850..3535959) Spirochaeta smaragdinae DSM 11293 9491413 YP_003804981.1 CDS Spirs_3291 NC_014364.1 3536139 3536819 D KEGG: spu:592801 similar to eukaryotic translation elongation factor; SPTR: cell surface protein; hypothetical protein 3536139..3536819 Spirochaeta smaragdinae DSM 11293 9491414 YP_003804982.1 CDS Spirs_3292 NC_014364.1 3536986 3537966 D COGs: COG2855 membrane protein; InterPro IPR004684:IPR018383; KEGG: hor:Hore_05460 conserved hypothetical integral membrane protein TIGR00698; PFAM: Uncharacterised protein family UPF0324; SPTR: Conserved hypothetical integral membrane protein TIGR00698; PFAM: Conserved hypothetical protein 698; TIGRFAM: conserved hypothetical integral membrane protein; hypothetical protein 3536986..3537966 Spirochaeta smaragdinae DSM 11293 9491415 YP_003804983.1 CDS Spirs_3293 NC_014364.1 3538045 3539190 R COGs: COG1929 glycerate kinase; InterPro IPR004381; KEGG: mta:Moth_0404 glycerate kinase; PFAM: glycerate kinase; PRIAM: glycerate kinase; SPTR: glycerate kinase; TIGRFAM: glycerate kinase; PFAM: glycerate kinase family; TIGRFAM: glycerate kinase; glycerate kinase complement(3538045..3539190) Spirochaeta smaragdinae DSM 11293 9491416 YP_003804984.1 CDS Spirs_3294 NC_014364.1 3539192 3539827 R InterPro IPR019734:IPR013026:IPR001440; KEGG: dap:Dacet_2926 tetratricopeptide repeat protein; PFAM: TPR repeat-containing protein; SPTR: Tetratricopeptide repeat protein; hypothetical protein complement(3539192..3539827) Spirochaeta smaragdinae DSM 11293 9491417 YP_003804985.1 CDS Spirs_3295 NC_014364.1 3539918 3541261 R COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474:IPR001120; KEGG: pmo:Pmob_0535 gluconate transporter; PFAM: gluconate transporter; SPTR: uncharacterized protein; PFAM: GntP family permease; TIGRFAM: gluconate transporter; gluconate transporter complement(3539918..3541261) Spirochaeta smaragdinae DSM 11293 9491418 YP_003804986.1 CDS Spirs_3296 NC_014364.1 3541288 3542130 R COGs: COG1237 metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: ckr:CKR_2525 hypothetical protein; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily; hypothetical protein complement(3541288..3542130) Spirochaeta smaragdinae DSM 11293 9491419 YP_003804987.1 CDS Spirs_3297 NC_014364.1 3542231 3542923 R COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: dsa:Desal_0038 GntR family transcriptional regulator; PFAM: GntR domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator complement(3542231..3542923) Spirochaeta smaragdinae DSM 11293 9491420 YP_003804988.1 CDS Spirs_3298 NC_014364.1 3543140 3544420 D COGs: COG0845 membrane-fusion protein; InterPro IPR006143; KEGG: cts:Ctha_0504 efflux transporter RND family, MFP subunit; SPTR: Efflux transporter RND family, MFP subunit; TIGRFAM: efflux transporter RND family, MFP subunit; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit 3543140..3544420 Spirochaeta smaragdinae DSM 11293 9491421 YP_003804989.1 CDS Spirs_3299 NC_014364.1 3544422 3545192 D COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: gau:GAU_0844 macrolide ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: macrolide ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 3544422..3545192 Spirochaeta smaragdinae DSM 11293 9491422 YP_003804990.1 CDS Spirs_3300 NC_014364.1 3545189 3546379 D COGs: COG0577 ABC-type antimicrobial peptide transport system permease; InterPro IPR003838; KEGG: cts:Ctha_0502 protein of unknown function DUF214; PFAM: protein of unknown function DUF214; SPTR: uncharacterized protein; PFAM: Predicted permease; hypothetical protein 3545189..3546379 Spirochaeta smaragdinae DSM 11293 9491423 YP_003804991.1 CDS Spirs_3301 NC_014364.1 3546411 3547922 R COGs: COG1473 metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR011650:IPR010168; KEGG: sth:STH1690 amino acid amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; SPTR: amino acid amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase family M20/M25/M40; peptidase dimerisation domain; TIGRFAM: amidohydrolase; amidohydrolase complement(3546411..3547922) Spirochaeta smaragdinae DSM 11293 9491424 YP_003804992.1 CDS Spirs_3302 NC_014364.1 3548097 3549194 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638:IPR018313; KEGG: hch:HCH_05807 amino acid ABC transporter periplasmic protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; SPTR: ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: lysine-arginine-ornithine-binding periplasmic protein; family 3 extracellular solute-binding protein 3548097..3549194 Spirochaeta smaragdinae DSM 11293 9491425 YP_003804993.1 CDS Spirs_3303 NC_014364.1 3549276 3550445 D COGs: COG4597 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: vvy:VV1556 ABC-type amino acid transporter, permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Amino acid ABC transporter permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 3549276..3550445 Spirochaeta smaragdinae DSM 11293 9491426 YP_003804994.1 CDS Spirs_3304 NC_014364.1 3550438 3551511 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: hch:HCH_05809 ABC-type amino acid transporter, permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type amino acid transporter, permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 3550438..3551511 Spirochaeta smaragdinae DSM 11293 9491427 YP_003804995.1 CDS Spirs_3305 NC_014364.1 3551508 3552308 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: cko:CKO_04684 hypothetical protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 3551508..3552308 Spirochaeta smaragdinae DSM 11293 9491428 YP_003804996.1 CDS Spirs_3306 NC_014364.1 3552337 3552957 D COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: rce:RC1_1835 translocator protein, LysE family protein; PFAM: lysine exporter (LYSE/YGGA); SPTR: translocator protein, LysE family protein; PFAM: LysE type translocator; lysine exporter LysE/YggA 3552337..3552957 Spirochaeta smaragdinae DSM 11293 9491429 YP_003804997.1 CDS Spirs_3307 NC_014364.1 3552962 3553600 D COGs: COG1280 threonine efflux protein; InterPro IPR001123; KEGG: par:Psyc_2059 LysE family amino acid efflux protein; PFAM: lysine exporter (LYSE/YGGA); SPTR: amino acid efflux pump, RhtB/LysE family; manually curated; PFAM: LysE type translocator; lysine exporter LysE/YggA 3552962..3553600 Spirochaeta smaragdinae DSM 11293 9491430 YP_003804998.1 CDS Spirs_3308 NC_014364.1 3553651 3554121 D COGs: COG2606 conserved hypothetical protein; InterPro IPR007214:IPR004369; KEGG: pdi:BDI_1373 transcriptional regulator; PFAM: YbaK/prolyl-tRNA synthetase associated region; SPTR: uncharacterized protein; TIGRFAM: ybaK/ebsC protein; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein; ybaK/ebsC protein 3553651..3554121 Spirochaeta smaragdinae DSM 11293 9491431 YP_003804999.1 CDS Spirs_3309 NC_014364.1 3554279 3555841 D InterPro IPR020864; KEGG: spe:Spro_2388 membrane attack complex component/perforin/complement C9; PFAM: membrane attack complex component/perforin (MACPF) domain; SPTR: membrane attack complex component/perforin/complement C9; PFAM: MAC/Perforin domain; membrane attack complex component/perforin (MACPF) domain-containing protein 3554279..3555841 Spirochaeta smaragdinae DSM 11293 9491432 YP_003805000.1 CDS Spirs_3310 NC_014364.1 3556016 3556816 D COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638:IPR018313; KEGG: ckr:CKR_0630 hypothetical protein; PFAM: extracellular solute-binding protein family 3; SMART: extracellular solute-binding protein family 3; ionotropic glutamate receptor; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3; family 3 extracellular solute-binding protein 3556016..3556816 Spirochaeta smaragdinae DSM 11293 9491433 YP_003805001.1 CDS Spirs_3311 NC_014364.1 3556830 3557471 D COGs: COG0765 ABC-type amino acid transporter permease; InterPro IPR000515:IPR010065; KEGG: ckr:CKR_0629 hypothetical protein; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Amino acid ABC transporter permease; TIGRFAM: polar amino acid ABC transporter inner membrane subunit; PFAM: Binding-protein-dependent transporter inner membrane component; TIGRFAM: amine acid ABC transporter permease, 3-TM region, His/Glu/Gln/Arg/opine family; polar amino acid ABC transporter inner membrane subunit 3556830..3557471 Spirochaeta smaragdinae DSM 11293 9491434 YP_003805002.1 CDS Spirs_3312 NC_014364.1 3557464 3558246 D COGs: COG1126 ABC-type polar amino acid transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: dac:Daci_5537 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 3557464..3558246 Spirochaeta smaragdinae DSM 11293 9491435 YP_003805003.1 CDS Spirs_3313 NC_014364.1 3558293 3559486 R InterPro IPR013519; KEGG: pin:Ping_0512 PKD domain-containing protein; SPTR: Quinoprotein (ISS); PKD domain-containing protein complement(3558293..3559486) Spirochaeta smaragdinae DSM 11293 9491436 YP_003805004.1 CDS Spirs_3314 NC_014364.1 3559638 3560759 D COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR017896:IPR001395:IPR017900; KEGG: aoe:Clos_1215 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; manually curated; PFAM: Aldo/keto reductase family; aldo/keto reductase 3559638..3560759 Spirochaeta smaragdinae DSM 11293 9491437 YP_003805005.1 CDS Spirs_3315 NC_014364.1 3560896 3562410 R COGs: COG4690 Dipeptidase; InterPro IPR005322; KEGG: afw:Anae109_3441 peptidase U34 dipeptidase; PFAM: peptidase U34 dipeptidase; SPTR: dipeptidase; PFAM: peptidase family C69; peptidase U34 dipeptidase complement(3560896..3562410) Spirochaeta smaragdinae DSM 11293 9491438 YP_003805006.1 CDS Spirs_3316 NC_014364.1 3562614 3563357 D COGs: COG3884 acyl-ACP thioesterase; InterPro IPR002864; KEGG: srm:SRM_00055 acyl-ACP thioesterase; PFAM: acyl-ACP thioesterase; SPTR: acyl-ACP thioesterase superfamily; PFAM: acyl-ACP thioesterase; acyl-ACP thioesterase 3562614..3563357 Spirochaeta smaragdinae DSM 11293 9491439 YP_003805007.1 CDS Spirs_3317 NC_014364.1 3563524 3564936 D COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: dsy:DSY4777 hypothetical protein; PFAM: Na+/H+ antiporter NhaC-like; SPTR: uncharacterized protein; PFAM: Na+/H+ antiporter family; Na+/H+ antiporter NhaC 3563524..3564936 Spirochaeta smaragdinae DSM 11293 9491440 YP_003805008.1 CDS Spirs_3318 NC_014364.1 3565103 3565378 R KEGG: pfs:PFLU1557 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3565103..3565378) Spirochaeta smaragdinae DSM 11293 9491441 YP_003805009.1 CDS Spirs_3319 NC_014364.1 3565483 3567000 D COGs: COG2078 conserved hypothetical protein; InterPro IPR002733; KEGG: sfu:Sfum_1299 AMMECR1 domain-containing protein; PFAM: AMMECR1 domain protein; SPTR: AMMECR1 domain protein; PFAM: AMMECR1; TIGRFAM: conserved hypothetical protein TIGR00296; AMMECR1 domain-containing protein 3565483..3567000 Spirochaeta smaragdinae DSM 11293 9491442 YP_003805010.1 CDS Spirs_3320 NC_014364.1 3566927 3567835 R COGs: COG1355 dioxygenase; KEGG: tde:TDE2539 hypothetical protein; SPTR: Conserved domain protein; PFAM: Memo-like protein; hypothetical protein complement(3566927..3567835) Spirochaeta smaragdinae DSM 11293 9491443 YP_003805011.1 CDS Spirs_3321 NC_014364.1 3567832 3570594 R KEGG: tde:TDE2540 lipoprotein; SPTR: Lipoprotein, ; PFAM: protein of unknown function (DUF3160); lipoprotein complement(3567832..3570594) Spirochaeta smaragdinae DSM 11293 9491444 YP_003805012.1 CDS Spirs_3322 NC_014364.1 3570638 3572110 R COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR011851:IPR019900:IPR018212; KEGG: dsa:Desal_1778 sodium/proline symporter; PFAM: Na+/solute symporter; SPTR: Sodium/proline symporter; TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; PFAM: Sodium:solute symporter family; TIGRFAM: sodium/proline symporter; SSS sodium solute transporter superfamily; sodium/proline symporter complement(3570638..3572110) Spirochaeta smaragdinae DSM 11293 9491445 YP_003805013.1 CDS Spirs_3323 NC_014364.1 3572283 3573257 D COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR020449:IPR000005:IPR018062; KEGG: msi:Msm_0775 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 3572283..3573257 Spirochaeta smaragdinae DSM 11293 9491446 YP_003805014.1 CDS Spirs_3324 NC_014364.1 3573377 3575764 D COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR000731; KEGG: tde:TDE2006 hypothetical protein; SPTR: membrane protein, ; PFAM: MMPL family; hypothetical protein 3573377..3575764 Spirochaeta smaragdinae DSM 11293 9491447 YP_003805015.1 CDS Spirs_3325 NC_014364.1 3575791 3576606 D KEGG: pgn:PGN_1919 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1329); hypothetical protein 3575791..3576606 Spirochaeta smaragdinae DSM 11293 9491448 YP_003805016.1 CDS Spirs_3326 NC_014364.1 3576606 3577880 D KEGG: tde:TDE2011 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3576606..3577880 Spirochaeta smaragdinae DSM 11293 9491449 YP_003805017.1 CDS Spirs_3327 NC_014364.1 3578011 3579792 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953:IPR010960; KEGG: amt:Amet_3460 flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: Flavocytochrome C; TIGRFAM: flavocytochrome C; PFAM: FAD binding domain; FMN-binding domain; TIGRFAM: flavocytochrome C; flavocytochrome C 3578011..3579792 Spirochaeta smaragdinae DSM 11293 9491450 YP_003805018.1 CDS Spirs_3328 NC_014364.1 3579881 3581986 R COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: gym:GYMC10_4315 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/crystallin J1; SPTR: ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylglycohydrolase; ADP-ribosylation/crystallin J1 complement(3579881..3581986) Spirochaeta smaragdinae DSM 11293 9491451 YP_003805019.1 CDS Spirs_3329 NC_014364.1 3582026 3583429 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_4317 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3582026..3583429) Spirochaeta smaragdinae DSM 11293 9491452 YP_003805020.1 CDS Spirs_3330 NC_014364.1 3583440 3584327 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_4318 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; sugar ABC transporter permease complement(3583440..3584327) Spirochaeta smaragdinae DSM 11293 9491453 YP_003805021.1 CDS Spirs_3331 NC_014364.1 3584321 3585220 R COGs: COG4209 ABC-type polysaccharide transporter permease; InterPro IPR000515; KEGG: gym:GYMC10_4319 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3584321..3585220) Spirochaeta smaragdinae DSM 11293 9491454 YP_003805022.1 CDS Spirs_3332 NC_014364.1 3585220 3585951 R COGs: COG0372 citrate synthase; InterPro IPR002020:IPR019810; KEGG: tal:Thal_1455 citrate synthase; PFAM: citrate synthase; SPTR: citrate synthase; PFAM: citrate synthase; citrate synthase complement(3585220..3585951) Spirochaeta smaragdinae DSM 11293 9491455 YP_003805023.1 CDS Spirs_3333 NC_014364.1 3585944 3586600 R COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR011761; KEGG: cwo:Cwoe_1304 CoA-binding protein; SPTR: CoA-binding domain protein; CoA-binding protein complement(3585944..3586600) Spirochaeta smaragdinae DSM 11293 9491456 YP_003805024.1 CDS Spirs_3334 NC_014364.1 3586597 3588000 R COGs: COG1042 acyl-CoA synthetase (NDP forming); InterPro IPR003781; KEGG: CoA-binding protein; PFAM: CoA-binding domain protein; SPTR: acetyl-CoA synthase; PFAM: CoA binding domain; CoA-binding protein complement(3586597..3588000) Spirochaeta smaragdinae DSM 11293 9491457 YP_003805025.1 CDS Spirs_3335 NC_014364.1 3587997 3588998 R COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: hor:Hore_04650 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/crystallin J1; SPTR: ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylglycohydrolase; ADP-ribosylation/crystallin J1 complement(3587997..3588998) Spirochaeta smaragdinae DSM 11293 9491458 YP_003805026.1 CDS Spirs_3336 NC_014364.1 3589003 3590013 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tex:Teth514_0985 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: LacI family transcriptional repressor; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3589003..3590013) Spirochaeta smaragdinae DSM 11293 9491459 YP_003805027.1 CDS Spirs_3337 NC_014364.1 3590230 3591366 R COGs: COG1453 oxidoreductase of the aldo/keto reductase family; InterPro IPR017896:IPR001395:IPR001450:IPR017900; KEGG: cdl:CDR20291_3047 oxidoreductase; PFAM: aldo/keto reductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: oxidoreductase; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(3590230..3591366) Spirochaeta smaragdinae DSM 11293 9491460 YP_003805028.1 CDS Spirs_3338 NC_014364.1 3591453 3592418 R COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR001395; KEGG: dge:Dgeo_2239 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: Aldo/keto reductase; PFAM: Aldo/keto reductase family; aldo/keto reductase complement(3591453..3592418) Spirochaeta smaragdinae DSM 11293 9491461 YP_003805029.1 CDS Spirs_3339 NC_014364.1 3592584 3592985 R COGs: COG0789 transcriptional regulator protein; InterPro IPR000551:IPR015358; KEGG: dae:Dtox_1332 transcriptional regulator, MerR family; PFAM: regulatory protein MerR; transcription regulator MerR DNA binding; SMART: regulatory protein MerR; SPTR: transcriptional regulator, MerR family; PFAM: MerR, DNA binding; MerR family regulatory protein; MerR family transcriptional regulator complement(3592584..3592985) Spirochaeta smaragdinae DSM 11293 9491462 YP_003805030.1 CDS Spirs_3341 NC_014364.1 3593535 3594245 R KEGG: sde:Sde_1498 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3593535..3594245) Spirochaeta smaragdinae DSM 11293 9491464 YP_003805031.1 CDS Spirs_3342 NC_014364.1 3594290 3594874 R InterPro IPR001647; KEGG: pla:Plav_0885 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(3594290..3594874) Spirochaeta smaragdinae DSM 11293 9491465 YP_003805032.1 CDS Spirs_3343 NC_014364.1 3594917 3597511 R COGs: COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system; InterProIPR000014:IPR003594:IPR001789:IPR005467:IPR 004358:IPR013767; KEGG: dal:Dalk_1499 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor hybrid histidine kinase complement(3594917..3597511) Spirochaeta smaragdinae DSM 11293 9491466 YP_003805033.1 CDS Spirs_3345 NC_014364.1 3597981 3598979 D KEGG: amr:AM1_3453 hypothetical protein; SPTR: Conserved domain protein; PFAM: protein of unknown function DUF88; hypothetical protein 3597981..3598979 Spirochaeta smaragdinae DSM 11293 9491468 YP_003805034.1 CDS Spirs_3346 NC_014364.1 3598960 3600801 R COGs: COG2206 HD-GYP domain; InterPro IPR003660:IPR003607:IPR006674:IPR006675; KEGG: gem:GM21_1090 metal dependent phosphohydrolase; PFAM: metal-dependent phosphohydrolase HD sub domain; histidine kinase HAMP region domain protein; SMART: metal-dependent phosphohydrolase HD region; histidine kinase HAMP region domain protein; SPTR: metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: HD domain; HAMP domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase complement(3598960..3600801) Spirochaeta smaragdinae DSM 11293 9491469 YP_003805035.1 CDS Spirs_3347 NC_014364.1 3600826 3601461 D COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: esi:Exig_1420 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 3600826..3601461 Spirochaeta smaragdinae DSM 11293 9491470 YP_003805036.1 CDS Spirs_3348 NC_014364.1 3601403 3602206 R COGs: COG1119 ABC-type molybdenum transporter ATPase component/photorepair protein PhrA; InterPro IPR003593:IPR003439; KEGG: cte:CT0753 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ATPase; PFAM: ABC transporter; ABC transporter complement(3601403..3602206) Spirochaeta smaragdinae DSM 11293 9491471 YP_003805037.1 CDS Spirs_3349 NC_014364.1 3602344 3602784 D KEGG: caa:Caka_2024 hypothetical protein; SPTR: uncharacterized protein; PFAM: transmembrane protein (PGPGW); hypothetical protein 3602344..3602784 Spirochaeta smaragdinae DSM 11293 9491472 YP_003805038.1 CDS Spirs_3350 NC_014364.1 3602771 3603268 R KEGG: mlo:mlr3740 pseudouridine synthase; SPTR: uncharacterized protein; hypothetical protein complement(3602771..3603268) Spirochaeta smaragdinae DSM 11293 9491473 YP_003805039.1 CDS Spirs_3351 NC_014364.1 3603294 3604802 R COGs: COG0280 phosphotransacetylase; InterPro IPR001387:IPR013096:IPR002505; KEGG: ddf:DEFDS_1240 phosphate butyryltransferase; PFAM: cupin; helix-turn-helix domain protein; phosphate acetyl/butaryl transferase; SMART: helix-turn-helix domain protein; SPTR: phosphate butyryltransferase; PFAM: Cupin domain; phosphate acetyl/butaryl transferase; Helix-turn-helix; XRE family transcriptional regulator complement(3603294..3604802) Spirochaeta smaragdinae DSM 11293 9491474 YP_003805040.1 CDS Spirs_3352 NC_014364.1 3604855 3605925 R COGs: COG3426 Butyrate kinase; InterPro IPR011245:IPR000890; KEGG: nth:Nther_2700 butyrate kinase; PFAM: acetate and butyrate kinase; SPTR: Butyrate kinase; TIGRFAM: butyrate kinase; PFAM: acetokinase family; TIGRFAM: butyrate kinase; butyrate kinase complement(3604855..3605925) Spirochaeta smaragdinae DSM 11293 9491475 YP_003805041.1 CDS Spirs_3353 NC_014364.1 3605922 3606818 R COGs: COG0280 phosphotransacetylase; InterPro IPR012147:IPR002505; KEGG: tit:Thit_1910 phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; PRIAM: phosphate butyryltransferase; SPTR: phosphate butyryltransferase; PFAM: phosphate acetyl/butaryl transferase; phosphate butyryltransferase complement(3605922..3606818) Spirochaeta smaragdinae DSM 11293 9491476 YP_003805042.1 CDS Spirs_3354 NC_014364.1 3606815 3607411 R COGs: COG1014 pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase subunit gamma; InterPro IPR019752; KEGG: bth:BT_0429 indolepyruvate oxidoreductase subunit beta; PFAM: pyruvate/ketoisovalerate oxidoreductase; SPTR: indolepyruvate oxidoreductase subunit iorB; PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: indolepyruvate ferredoxin oxidoreductase subunit beta; pyruvate/ketoisovalerate oxidoreductase complement(3606815..3607411) Spirochaeta smaragdinae DSM 11293 9491477 YP_003805043.1 CDS Spirs_3355 NC_014364.1 3607408 3609027 R COGs: COG4231 indolepyruvate ferredoxin oxidoreductase alpha and subunit betas; InterPro IPR011766; KEGG: pph:Ppha_0075 indolepyruvate ferredoxin oxidoreductase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: indolepyruvate ferredoxin oxidoreductase, alpha chain; PFAM: domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: indolepyruvate ferredoxin oxidoreductase, subunit alpha; thiamine pyrophosphate protein TPP binding domain-containing protein complement(3607408..3609027) Spirochaeta smaragdinae DSM 11293 9491478 YP_003805044.1 CDS Spirs_3356 NC_014364.1 3609199 3609666 D COGs: COG1522 transcriptional regulators; InterProIPR019888:IPR000485:IPR001845:IPR019887:IPR 019885; KEGG: pat:Patl_2996 AsnC family transcriptional regulator; PFAM: transcription regulator, AsnC-type-like; regulatory protein ArsR; SMART: transcription regulator, AsnC-type; SPTR: Lrp/AsnC family transcriptional regulator; PFAM: MarR family; AsnC family; AsnC family transcriptional regulator 3609199..3609666 Spirochaeta smaragdinae DSM 11293 9491479 YP_003805045.1 CDS Spirs_3357 NC_014364.1 3609914 3611581 D InterPro IPR010916; KEGG: sha:SH0326 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3609914..3611581 Spirochaeta smaragdinae DSM 11293 9491480 YP_003805046.1 CDS Spirs_3358 NC_014364.1 3612236 3613072 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: pmo:Pmob_0307 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3612236..3613072) Spirochaeta smaragdinae DSM 11293 9491482 YP_003805047.1 CDS Spirs_3359 NC_014364.1 3613069 3613968 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pmo:Pmob_0306 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3613069..3613968) Spirochaeta smaragdinae DSM 11293 9491483 YP_003805048.1 CDS Spirs_3360 NC_014364.1 3613972 3615306 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: pmo:Pmob_0305 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3613972..3615306) Spirochaeta smaragdinae DSM 11293 9491484 YP_003805049.1 CDS Spirs_3361 NC_014364.1 3615303 3616115 R COGs: COG2820 Uridine phosphorylase; InterPro IPR000845:IPR018016; KEGG: pmo:Pmob_0304 purine phosphorylase family 1; PFAM: purine or other phosphorylase family 1; SPTR: Purine or other phosphorylase family 1; PFAM: phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD); purine or other phosphorylase family 1 complement(3615303..3616115) Spirochaeta smaragdinae DSM 11293 9491485 YP_003805050.1 CDS Spirs_3362 NC_014364.1 3616126 3616929 R COGs: COG2188 transcriptional regulators; InterPro IPR000524:IPR011663; KEGG: tle:Tlet_1429 GntR family transcriptional regulator; PFAM: UbiC transcription regulator-associated domain protein; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; UTRA domain; GntR family transcriptional regulator complement(3616126..3616929) Spirochaeta smaragdinae DSM 11293 9491486 YP_003805051.1 CDS Spirs_3364 NC_014364.1 3617831 3619012 D COGs: COG2856 Zn peptidase; InterPro IPR001387:IPR010359; KEGG: plt:Plut_1806 hypothetical protein; PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix; Domain of unknown function (DUF955); hypothetical protein 3617831..3619012 Spirochaeta smaragdinae DSM 11293 9491488 YP_003805052.1 CDS Spirs_3365 NC_014364.1 3619009 3619161 D SPTR: uncharacterized protein; hypothetical protein 3619009..3619161 Spirochaeta smaragdinae DSM 11293 9491489 YP_003805053.1 CDS Spirs_3366 NC_014364.1 3619257 3619562 D InterPro IPR002934; KEGG: chy:CHY_2495 nucleotidyltransferase domain-containing protein; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain; DNA polymerase beta domain-containing protein region 3619257..3619562 Spirochaeta smaragdinae DSM 11293 9491490 YP_003805054.1 CDS Spirs_3368 NC_014364.1 3619969 3621204 R COGs: COG3135 Uncharacterized protein involved in benzoate metabolism; InterPro IPR004711; KEGG: mta:Moth_1772 benzoate transporter; PFAM: Benzoate membrane transporter; SPTR: Benzoate transporter; PFAM: Benzoate membrane transporter; TIGRFAM: benzoate transporter; Benzoate membrane transporter complement(3619969..3621204) Spirochaeta smaragdinae DSM 11293 9491492 YP_003805055.1 CDS Spirs_3369 NC_014364.1 3621280 3622254 R COGs: COG0329 dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR002220; KEGG: mjl:Mjls_4205 dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase; SPTR: dihydrodipicolinate synthetase; PFAM: dihydrodipicolinate synthetase family; dihydrodipicolinate synthetase complement(3621280..3622254) Spirochaeta smaragdinae DSM 11293 9491493 YP_003805056.1 CDS Spirs_3370 NC_014364.1 3622546 3623226 D COGs: COG1802 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: rop:ROP_pROB02-02020 naphthalene degradation regulatory protein; PFAM: GntR family transcriptional regulator; regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: naphthalene degradation regulator protein; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; GntR family transcriptional regulator 3622546..3623226 Spirochaeta smaragdinae DSM 11293 9491494 YP_003805057.1 CDS Spirs_3372 NC_014364.1 3623947 3624201 D InterPro IPR003756:IPR006442; KEGG: mmw:Mmwyl1_1402 prevent-host-death family protein; PFAM: protein of unknown function DUF172; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein 3623947..3624201 Spirochaeta smaragdinae DSM 11293 9491496 YP_003805058.1 CDS Spirs_3373 NC_014364.1 3624194 3624454 D COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: cti:pRALTA_0043 toxin of the YoeB-YefM toxin-antitoxin system; PFAM: Addiction module toxin Txe/YoeB; SPTR: Toxin of the YoeB-YefM toxin-antitoxin system; TIGRFAM: addiction module toxin, Txe/YoeB family; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family; Txe/YoeB family addiction module toxin 3624194..3624454 Spirochaeta smaragdinae DSM 11293 9491497 YP_003805059.1 CDS Spirs_3374 NC_014364.1 3624757 3626217 R COGs: COG0644 dehydrogenase (flavoprotein); InterPro IPR003953; KEGG: phe:Phep_0457 hypothetical protein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; SPTR: FAD dependent oxidoreductase; PFAM: FAD binding domain; fumarate reductase/succinate dehydrogenase flavoprotein domain-containing protein complement(3624757..3626217) Spirochaeta smaragdinae DSM 11293 9491498 YP_003805060.1 CDS Spirs_3375 NC_014364.1 3626247 3627959 R KEGG: mth:MTH1540 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3626247..3627959) Spirochaeta smaragdinae DSM 11293 9491499 YP_003805061.1 CDS Spirs_3376 NC_014364.1 3628279 3628518 R KEGG: mta:Moth_0382 vanillic acid non-oxidative decarboxylation gene-like; SPTR: Vanillic acid non-oxidative decarboxylation gene-like; vanillic acid non-oxidative decarboxylation protein complement(3628279..3628518) Spirochaeta smaragdinae DSM 11293 9491500 YP_003805062.1 CDS Spirs_3377 NC_014364.1 3628523 3629953 R COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: mta:Moth_0381 carboxylyase-like protein; PFAM: carboxylyase-related protein; SPTR: carboxylyase-related protein; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; UbiD family decarboxylase complement(3628523..3629953) Spirochaeta smaragdinae DSM 11293 9491501 YP_003805063.1 CDS Spirs_3378 NC_014364.1 3630249 3631289 D COGs: COG2358 TRAP-type uncharacterized transporter periplasmic component; InterPro IPR011852; KEGG: aco:Amico_1806 TRAP transporter solute receptor, TAXI family; SPTR: uncharacterized protein; TIGRFAM: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; TRAP transporter solute receptor, TAXI family 3630249..3631289 Spirochaeta smaragdinae DSM 11293 9491502 YP_003805064.1 CDS Spirs_3379 NC_014364.1 3631357 3633294 D COGs: COG4666 TRAP-type uncharacterized transporter fused permeases; InterPro IPR010656:IPR011853; KEGG: drm:Dred_3211 TRAP transporter 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: uncharacterized protein; TIGRFAM: TRAP transporter 4TM/12TM fusion protein; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter 4TM/12TM fusion protein; TRAP transporter 4TM/12TM fusion protein 3631357..3633294 Spirochaeta smaragdinae DSM 11293 9491503 YP_003805065.1 CDS Spirs_3380 NC_014364.1 3633291 3634286 D KEGG: dhd:Dhaf_1110 hypothetical protein; SPTR: uncharacterized protein; PFAM: uroporphyrinogen decarboxylase (URO-D); hypothetical protein 3633291..3634286 Spirochaeta smaragdinae DSM 11293 9491504 YP_003805066.1 CDS Spirs_3381 NC_014364.1 3634298 3635803 D COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590:IPR016160; KEGG: tna:CTN_1548 aldehyde dehydrogenase; PFAM: aldehyde dehydrogenase; SPTR: succinate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase family; aldehyde dehydrogenase 3634298..3635803 Spirochaeta smaragdinae DSM 11293 9491505 YP_003805067.1 CDS Spirs_3382 NC_014364.1 3635841 3636995 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: ere:EUBREC_0100 alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; SPTR: uncharacterized protein; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 3635841..3636995 Spirochaeta smaragdinae DSM 11293 9491506 YP_003805068.1 CDS Spirs_3383 NC_014364.1 3637031 3637402 D KEGG: dsa:Desal_0749 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3637031..3637402 Spirochaeta smaragdinae DSM 11293 9491507 YP_003805069.1 CDS Spirs_3384 NC_014364.1 3637380 3638294 R COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: sga:GALLO_0047 transcriptional regulator, LysR family; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator complement(3637380..3638294) Spirochaeta smaragdinae DSM 11293 9491508 YP_003805070.1 CDS Spirs_3385 NC_014364.1 3638422 3638832 D KEGG: plt:Plut_1806 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3638422..3638832 Spirochaeta smaragdinae DSM 11293 9491509 YP_003805071.1 CDS Spirs_3386 NC_014364.1 3638893 3639771 R COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR018060:IPR000005; KEGG: bth:BT_1235 AraC-type transcription regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(3638893..3639771) Spirochaeta smaragdinae DSM 11293 9491510 YP_003805072.1 CDS Spirs_3387 NC_014364.1 3639955 3641055 D KEGG: lsp:Bsph_3731 DNA translocase FtsK; SPTR: Secreted hydrolase; hypothetical protein 3639955..3641055 Spirochaeta smaragdinae DSM 11293 9491511 YP_003805073.1 CDS Spirs_3388 NC_014364.1 3641209 3642051 D COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198:IPR002347; KEGG: mrb:Mrub_0175 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 3641209..3642051 Spirochaeta smaragdinae DSM 11293 9491512 YP_003805074.1 CDS Spirs_3389 NC_014364.1 3642734 3644443 D COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR000014:IPR001610:IPR003607:IPR013655:IPR 013656:IPR006674:IPR000700; KEGG: tai:Taci_0097 PAS/PAC sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; PAS fold-3 domain protein; hypothetical protein; SMART: PAC repeat-containing protein; PAS domain containing protein; metal-dependent phosphohydrolase HD region; SPTR: uncharacterized protein; TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor protein 3642734..3644443 Spirochaeta smaragdinae DSM 11293 9491513 YP_003805075.1 CDS Spirs_3390 NC_014364.1 3644465 3646636 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004090:IPR008611; KEGG: tde:TDE0640 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer 3644465..3646636 Spirochaeta smaragdinae DSM 11293 9491514 YP_003805076.1 CDS Spirs_3391 NC_014364.1 3646859 3647935 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000014:IPR000792:IPR013767; KEGG: pca:Pcar_2025 two component sensor histidine kinase; PFAM: regulatory protein LuxR; PAS fold domain protein; SMART: regulatory protein LuxR; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box; LuxR family transcriptional regulator 3646859..3647935 Spirochaeta smaragdinae DSM 11293 9491515 YP_003805077.1 CDS Spirs_3394 NC_014364.1 3649532 3650395 R COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: cdl:CDR20291_2979 sugar-bisphosphate aldolase; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: uncharacterized protein; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase complement(3649532..3650395) Spirochaeta smaragdinae DSM 11293 9491518 YP_003805078.1 CDS Spirs_3395 NC_014364.1 3650434 3651279 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: rlt:Rleg2_5474 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: permease of ABC transporter; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3650434..3651279) Spirochaeta smaragdinae DSM 11293 9491519 YP_003805079.1 CDS Spirs_3396 NC_014364.1 3651282 3652175 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: mlo:mlr7226 sugar ABC transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3651282..3652175) Spirochaeta smaragdinae DSM 11293 9491520 YP_003805080.1 CDS Spirs_3397 NC_014364.1 3652248 3653507 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: ara:Arad_8979 sugar ABC transporter; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3652248..3653507) Spirochaeta smaragdinae DSM 11293 9491521 YP_003805081.1 CDS Spirs_3398 NC_014364.1 3653793 3654584 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: tte:TTE2588 sugar metabolism transcriptional regulator; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: transcriptional regulator of sugar metabolism; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator 3653793..3654584 Spirochaeta smaragdinae DSM 11293 9491522 YP_003805082.1 CDS Spirs_3399 NC_014364.1 3654611 3655813 D COGs: COG4809 ADP-dependent phosphofructokinase/glucokinase; InterPro IPR007666; KEGG: hypothetical protein; SPTR: uncharacterized protein; PFAM: ADP-specific phosphofructokinase/glucokinase conserved region; hypothetical protein 3654611..3655813 Spirochaeta smaragdinae DSM 11293 9491523 YP_003805083.1 CDS Spirs_3400 NC_014364.1 3655818 3656594 D COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR014036; KEGG: saz:Sama_1193 GlpR family transcriptional regulator; PFAM: regulatory protein DeoR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, deoR family; regulatory protein DeoR 3655818..3656594 Spirochaeta smaragdinae DSM 11293 9491524 YP_003805084.1 CDS Spirs_3401 NC_014364.1 3656609 3657967 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cno:NT01CX_0730 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: Mate efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(3656609..3657967) Spirochaeta smaragdinae DSM 11293 9491525 YP_003805085.1 CDS Spirs_3402 NC_014364.1 3658124 3658396 R KEGG: ppd:Ppro_2532 hypothetical protein; SPTR: uncharacterized protein; PFAM: Plasmid maintenance system killer protein; TIGRFAM: addiction module toxin, RelE/StbE family; hypothetical protein complement(3658124..3658396) Spirochaeta smaragdinae DSM 11293 9491526 YP_003805086.1 CDS Spirs_3403 NC_014364.1 3658389 3658646 R InterPro IPR006442; KEGG: pmx:PERMA_1336 prevent-host-death family protein; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(3658389..3658646) Spirochaeta smaragdinae DSM 11293 9491527 YP_003805087.1 CDS Spirs_3404 NC_014364.1 3658936 3661053 R COGs: COG3920 Signal transduction histidine kinase; InterProIPR001789:IPR000014:IPR013655:IPR003594:IPR 000700; KEGG: lbf:LBF_2370 signal transduction histidine kinase; PFAM: response regulator receiver; PAS fold-3 domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; PAS domain containing protein; SPTR: two-component response regulator; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase complement(3658936..3661053) Spirochaeta smaragdinae DSM 11293 9491528 YP_003805088.1 CDS Spirs_3405 NC_014364.1 3661073 3661519 R COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: dsa:Desal_3034 chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: chemotaxis protein CheW; PFAM: CheW-like domain; chemotaxis protein CheW complement(3661073..3661519) Spirochaeta smaragdinae DSM 11293 9491529 YP_003805089.1 CDS Spirs_3406 NC_014364.1 3661529 3663130 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: gem:GM21_1105 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; SMART: chemotaxis sensory transducer; SPTR: methyl-accepting chemotaxis sensory transducer; PFAM: methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(3661529..3663130) Spirochaeta smaragdinae DSM 11293 9491530 YP_003805090.1 CDS Spirs_3407 NC_014364.1 3663348 3663656 D InterPro IPR001387; KEGG: tde:TDE2445 DNA-binding protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: DNA-binding protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator 3663348..3663656 Spirochaeta smaragdinae DSM 11293 9491531 YP_003805091.1 CDS Spirs_3408 NC_014364.1 3663788 3664618 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: dsa:Desal_0501 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3663788..3664618) Spirochaeta smaragdinae DSM 11293 9491532 YP_003805092.1 CDS Spirs_3409 NC_014364.1 3664615 3665748 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: dde:Dde_3658 glucose transporter permease; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: glucose transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3664615..3665748) Spirochaeta smaragdinae DSM 11293 9491533 YP_003805093.1 CDS Spirs_3410 NC_014364.1 3665852 3667165 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: dde:Dde_3657 sugar ABC transporter substrate-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Sugar ABC transporter substrate-binding protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3665852..3667165) Spirochaeta smaragdinae DSM 11293 9491534 YP_003805094.1 CDS Spirs_3411 NC_014364.1 3667396 3668916 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR001789:IPR018060:IPR000005:IPR018062:IPR 020449; KEGG: cbe:Cbei_1381 response regulator receiver protein; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(3667396..3668916) Spirochaeta smaragdinae DSM 11293 9491535 YP_003805095.1 CDS Spirs_3412 NC_014364.1 3668909 3670675 R COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR010559:IPR003594:IPR005467; KEGG: cbe:Cbei_1382 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: histidine kinase internal region; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(3668909..3670675) Spirochaeta smaragdinae DSM 11293 9491536 YP_003805096.1 CDS Spirs_3413 NC_014364.1 3670672 3671676 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: cbe:Cbei_1380 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; sugar ABC transporter periplasmic protein complement(3670672..3671676) Spirochaeta smaragdinae DSM 11293 9491537 YP_003805097.1 CDS Spirs_3414 NC_014364.1 3671987 3673519 D COGs: COG1060 thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722; KEGG: tte:TTE1568 thiamine biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; radical SAM domain protein; SPTR: thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; PFAM: Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH; biotin and thiamin synthesis associated 3671987..3673519 Spirochaeta smaragdinae DSM 11293 9491538 YP_003805098.1 CDS Spirs_3415 NC_014364.1 3673506 3673811 D KEGG: bpy:Bphyt_4946 esterase; SPTR: uncharacterized protein; hypothetical protein 3673506..3673811 Spirochaeta smaragdinae DSM 11293 9491539 YP_003805099.1 CDS Spirs_3416 NC_014364.1 3673808 3675217 D COGs: COG1027 aspartate ammonia-lyase; InterPro IPR000362:IPR018951:IPR020557:IPR019775; KEGG: pca:Pcar_1630 aspartate ammonia-lyase; PFAM: fumarate lyase; Fumarase C-like; SPTR: aspartate ammonia-lyase; PFAM: Fumarase C C-terminus; Lyase; fumarate lyase 3673808..3675217 Spirochaeta smaragdinae DSM 11293 9491540 YP_003805100.1 CDS Spirs_3417 NC_014364.1 3675221 3676465 D COGs: COG1160 GTPase; InterPro IPR002917:IPR001806:IPR005225; KEGG: pca:Pcar_1629 GTPases; PFAM: GTP-binding protein HSR1-related; SPTR: Predicted GTPases; TIGRFAM: small GTP-binding protein; PFAM: GTPase of unknown function; TIGRFAM: small GTP-binding protein domain; small GTP-binding protein 3675221..3676465 Spirochaeta smaragdinae DSM 11293 9491541 YP_003805101.1 CDS Spirs_3418 NC_014364.1 3676527 3677561 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: cce:Ccel_1226 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(3676527..3677561) Spirochaeta smaragdinae DSM 11293 9491542 YP_003805102.1 CDS Spirs_3419 NC_014364.1 3677558 3678643 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: cce:Ccel_1225 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(3677558..3678643) Spirochaeta smaragdinae DSM 11293 9491543 YP_003805103.1 CDS Spirs_3420 NC_014364.1 3678640 3680169 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: cce:Ccel_1224 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ATP binding protein of ABC transporter; PFAM: ABC transporter; ABC transporter complement(3678640..3680169) Spirochaeta smaragdinae DSM 11293 9491544 YP_003805104.1 CDS Spirs_3421 NC_014364.1 3680245 3681231 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: cce:Ccel_1223 periplasmic binding protein/LacI transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: ABC transporter periplasmic-binding protein YtfQ; PFAM: family; sugar ABC transporter periplasmic protein complement(3680245..3681231) Spirochaeta smaragdinae DSM 11293 9491545 YP_003805105.1 CDS Spirs_3422 NC_014364.1 3681356 3682963 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789:IPR018060:IPR000005:IPR020449; KEGG: cce:Ccel_1228 two component AraC family transcriptional regulator; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component AraC family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(3681356..3682963) Spirochaeta smaragdinae DSM 11293 9491546 YP_003805106.1 CDS Spirs_3423 NC_014364.1 3682956 3684434 R COGs: COG2972 signal transduction protein with a C-terminal ATPase domain; InterPro IPR003660:IPR003594:IPR010559; KEGG: hau:Haur_2122 histidine kinase internal region; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: histidine kinase internal region; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(3682956..3684434) Spirochaeta smaragdinae DSM 11293 9491547 YP_003805107.1 CDS Spirs_3424 NC_014364.1 3684397 3685410 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR005479; KEGG: sro:Sros_6223 periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: family; sugar ABC transporter periplasmic protein complement(3684397..3685410) Spirochaeta smaragdinae DSM 11293 9491548 YP_003805108.1 CDS Spirs_3425 NC_014364.1 3685867 3686274 R COGs: COG3744 conserved hypothetical protein; InterPro IPR002716; KEGG: lil:LA0936 hypothetical protein; PFAM: twitching motility protein PilT; SPTR: uncharacterized protein; PFAM: PIN domain; twitching motility protein PilT complement(3685867..3686274) Spirochaeta smaragdinae DSM 11293 9491549 YP_003805109.1 CDS Spirs_3426 NC_014364.1 3686271 3686525 R InterPro IPR003756:IPR006442; KEGG: pph:Ppha_0754 prevent-host-death family protein; PFAM: protein of unknown function DUF172; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(3686271..3686525) Spirochaeta smaragdinae DSM 11293 9491550 YP_003805110.1 CDS Spirs_3427 NC_014364.1 3686759 3688120 D COGs: COG0371 glycerol dehydrogenase; InterPro IPR002658; KEGG: bcv:Bcav_1503 glycerol-1-phosphate dehydrogenase (NAD(P)(+)); PFAM: 3-dehydroquinate synthase; PRIAM: glycerol-1-phosphate dehydrogenase (NAD(P)(+)); SPTR: glycerol-1-phosphate dehydrogenase (NAD(P)(+)); PFAM: 3-dehydroquinate synthase; glycerol-1-phosphate dehydrogenase (NAD(P)(+)) 3686759..3688120 Spirochaeta smaragdinae DSM 11293 9491551 YP_003805111.1 CDS Spirs_3428 NC_014364.1 3688202 3689227 D COGs: COG1609 transcriptional regulators; InterPro IPR000843; KEGG: dfe:Dfer_4879 LacI family transcriptional regulator; PFAM: regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; LacI family transcriptional regulator 3688202..3689227 Spirochaeta smaragdinae DSM 11293 9491552 YP_003805112.1 CDS Spirs_3429 NC_014364.1 3689260 3690939 D COGs: COG1069 ribulose kinase; InterPro IPR005929:IPR018484:IPR018485; KEGG: sli:Slin_1239 L-ribulokinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: Ribulokinase; TIGRFAM: L-ribulokinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: L-ribulokinase; L-ribulokinase 3689260..3690939 Spirochaeta smaragdinae DSM 11293 9491553 YP_003805113.1 CDS Spirs_3430 NC_014364.1 3690952 3691647 D COGs: COG0235 ribulose-5-phosphate 4-epimerase and related epimerase and aldolase; InterPro IPR001303; KEGG: dfe:Dfer_2396 class II aldolase/adducin family protein; PFAM: class II aldolase/adducin family protein; SPTR: class II aldolase/adducin family protein; PFAM: class II Aldolase and Adducin N-terminal domain; TIGRFAM: L-ribulose-5-phosphate 4-epimerase; class II aldolase/adducin family protein 3690952..3691647 Spirochaeta smaragdinae DSM 11293 9491554 YP_003805114.1 CDS Spirs_3431 NC_014364.1 3691670 3693184 D COGs: COG2160 L-arabinose isomerase; InterPro IPR003762; KEGG: aba:acid345_0326 L-arabinose isomerase; PFAM: L-arabinose isomerase; PRIAM: L-arabinose isomerase; SPTR: L-arabinose isomerase; PFAM: L-arabinose isomerase; L-arabinose isomerase C-terminal domain; L-arabinose isomerase 3691670..3693184 Spirochaeta smaragdinae DSM 11293 9491555 YP_003805115.1 CDS Spirs_3432 NC_014364.1 3693314 3693994 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR012318; KEGG: plu:plu2771 hypothetical protein; PFAM: cyclic nucleotide-binding; SPTR: Similar to transcription regulator; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator complement(3693314..3693994) Spirochaeta smaragdinae DSM 11293 9491556 YP_003805116.1 CDS Spirs_3433 NC_014364.1 3694302 3696410 R COGs: COG0840 methyl-accepting chemotaxis protein; InterProIPR004089:IPR001450:IPR007202:IPR017900:IPR 004090:IPR017896; KEGG: ckr:CKR_1969 hypothetical protein; PFAM: chemotaxis sensory transducer; 4Fe-4S ferredoxin iron-sulfur binding domain protein; Fe-S cluster domain protein; SMART: chemotaxis sensory transducer; SPTR: uncharacterized protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; 4Fe-4S binding domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer complement(3694302..3696410) Spirochaeta smaragdinae DSM 11293 9491557 YP_003805117.1 CDS Spirs_3434 NC_014364.1 3696595 3697002 R InterPro IPR006016:IPR006015; KEGG: cte:CT1011 universal stress protein; PFAM: UspA domain protein; SPTR: Universal stress protein family; PFAM: Universal stress protein family; UspA domain-containing protein complement(3696595..3697002) Spirochaeta smaragdinae DSM 11293 9491558 YP_003805118.1 CDS Spirs_3435 NC_014364.1 3697002 3698237 R COGs: COG1914 Mn2+ and Fe2+ transporter of the NRAMP family; InterPro IPR001046; KEGG: cte:CT1010 natural resistance-associated macrophage protein family protein; PFAM: natural resistance-associated macrophage protein; SPTR: Natural resistance-associated macrophage protein family protein; PFAM: Natural resistance-associated macrophage protein; TIGRFAM: NRAMP (natural resistance-associated macrophage protein) metal ion transporters; natural resistance-associated macrophage protein complement(3697002..3698237) Spirochaeta smaragdinae DSM 11293 9491559 YP_003805119.1 CDS Spirs_3436 NC_014364.1 3698329 3699834 R COGs: COG3333 conserved hypothetical protein; InterPro IPR002823; KEGG: pmu:PM1681 hypothetical protein; PFAM: protein of unknown function DUF112 transmembrane; SPTR: uncharacterized protein; PFAM: tripartite tricarboxylate transporter TctA family; hypothetical protein complement(3698329..3699834) Spirochaeta smaragdinae DSM 11293 9491560 YP_003805120.1 CDS Spirs_3437 NC_014364.1 3699848 3700312 R KEGG: pmu:PM1680 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3699848..3700312) Spirochaeta smaragdinae DSM 11293 9491561 YP_003805121.1 CDS Spirs_3438 NC_014364.1 3700372 3701343 R COGs: COG3181 conserved hypothetical protein; InterPro IPR005064; KEGG: pmu:PM1679 hypothetical protein; PFAM: conserved hypothetical protein; SPTR: Twin-arginine translocation pathway signal; PFAM: tripartite tricarboxylate transporter family receptor; hypothetical protein complement(3700372..3701343) Spirochaeta smaragdinae DSM 11293 9491562 YP_003805122.1 CDS Spirs_3439 NC_014364.1 3701340 3702311 R COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); KEGG: cno:NT01CX_0354 metallo-beta-lactamase superfamily protein; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; hydrolase complement(3701340..3702311) Spirochaeta smaragdinae DSM 11293 9491563 YP_003805123.1 CDS Spirs_3440 NC_014364.1 3702320 3703315 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: transcriptional regulator family protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3702320..3703315) Spirochaeta smaragdinae DSM 11293 9491564 YP_003805124.1 CDS Spirs_3441 NC_014364.1 3703528 3704172 D InterPro IPR001647; KEGG: dol:Dole_0805 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 3703528..3704172 Spirochaeta smaragdinae DSM 11293 9491565 YP_003805125.1 CDS Spirs_3442 NC_014364.1 3704144 3705493 D COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: dol:Dole_0806 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein; outer membrane efflux protein 3704144..3705493 Spirochaeta smaragdinae DSM 11293 9491566 YP_003805126.1 CDS Spirs_3443 NC_014364.1 3705490 3706377 D COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: dol:Dole_0807 secretion protein HlyD; PFAM: secretion protein HlyD; SPTR: Secretion protein HlyD family protein; PFAM: HlyD family secretion protein; secretion protein HlyD 3705490..3706377 Spirochaeta smaragdinae DSM 11293 9491567 YP_003805127.1 CDS Spirs_3444 NC_014364.1 3706364 3707314 D COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: cts:Ctha_1315 ABC transporter-related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter 3706364..3707314 Spirochaeta smaragdinae DSM 11293 9491568 YP_003805128.1 CDS Spirs_3445 NC_014364.1 3707311 3708066 D COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593:IPR003439; KEGG: cpi:Cpin_2918 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: BAC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 3707311..3708066 Spirochaeta smaragdinae DSM 11293 9491569 YP_003805129.1 CDS Spirs_3446 NC_014364.1 3708063 3709166 D COGs: COG0842 ABC-type multidrug transporter permease; InterPro IPR013525:IPR013526:IPR000412; KEGG: dol:Dole_0810 ABC transporter; PFAM: ABC transporter; SPTR: ABC-2 type transporter; PFAM: ABC transporter; TIGRFAM: ABC transporter efflux protein, DrrB family; ABC transporter 3708063..3709166 Spirochaeta smaragdinae DSM 11293 9491570 YP_003805130.1 CDS Spirs_3447 NC_014364.1 3709170 3710279 D COGs: COG0842 ABC-type multidrug transporter permease; InterPro IPR013525:IPR000412; KEGG: dol:Dole_0811 ABC-2 type transporter; PFAM: ABC transporter; SPTR: ABC-2 type transporter; PFAM: ABC transporter; ABC transporter 3709170..3710279 Spirochaeta smaragdinae DSM 11293 9491571 YP_003805131.1 CDS Spirs_3448 NC_014364.1 3710459 3711397 R COGs: COG2390 transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: bpu:BPUM_1177 transcriptional regulator; PFAM: sugar-binding domain protein; SPTR: uncharacterized protein; PFAM: sugar-binding domain; DeoR family transcriptional regulator complement(3710459..3711397) Spirochaeta smaragdinae DSM 11293 9491572 YP_003805132.1 CDS Spirs_3449 NC_014364.1 3711394 3711912 R KEGG: ttr:Tter_2376 hypothetical protein; SPTR: uncharacterized protein; PFAM: adenylate kinase; hypothetical protein complement(3711394..3711912) Spirochaeta smaragdinae DSM 11293 9491573 YP_003805133.1 CDS Spirs_3450 NC_014364.1 3711928 3712776 R COGs: COG0191 fructose/tagatose bisphosphate aldolase; InterPro IPR000771; KEGG: tit:Thit_0120 fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase class-II; PRIAM: Tagatose-bisphosphate aldolase; SPTR: fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; ketose-bisphosphate aldolase complement(3711928..3712776) Spirochaeta smaragdinae DSM 11293 9491574 YP_003805134.1 CDS Spirs_3451 NC_014364.1 3712766 3713671 R COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: ctc:CTC00230 transcriptional repressor; PFAM: ROK family protein; SPTR: transcriptional regulator; PFAM: ROK family; ROK family protein complement(3712766..3713671) Spirochaeta smaragdinae DSM 11293 9491575 YP_003805135.1 CDS Spirs_3452 NC_014364.1 3713673 3714500 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_20610 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3713673..3714500) Spirochaeta smaragdinae DSM 11293 9491576 YP_003805136.1 CDS Spirs_3453 NC_014364.1 3714500 3715363 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: pjd:Pjdr2_6109 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3714500..3715363) Spirochaeta smaragdinae DSM 11293 9491577 YP_003805137.1 CDS Spirs_3455 NC_014364.1 3715968 3716987 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tit:Thit_1753 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3715968..3716987) Spirochaeta smaragdinae DSM 11293 9491579 YP_003805138.1 CDS Spirs_3456 NC_014364.1 3717173 3718222 R COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR002328; KEGG: cwo:Cwoe_5447 alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; TIGRFAM: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide A dehydrogenase; alcohol dehydrogenase GroES domain-containing protein complement(3717173..3718222) Spirochaeta smaragdinae DSM 11293 9491580 YP_003805139.1 CDS Spirs_3457 NC_014364.1 3718272 3719051 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: kol:Kole_0163 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(3718272..3719051) Spirochaeta smaragdinae DSM 11293 9491581 YP_003805140.1 CDS Spirs_3458 NC_014364.1 3719070 3720041 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: gka:GK1893 sugar ABC transporter (permease); PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(3719070..3720041) Spirochaeta smaragdinae DSM 11293 9491582 YP_003805141.1 CDS Spirs_3459 NC_014364.1 3720112 3721620 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: str:Sterm_4010 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(3720112..3721620) Spirochaeta smaragdinae DSM 11293 9491583 YP_003805142.1 CDS Spirs_3460 NC_014364.1 3721739 3722686 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: gka:GK1896 sugar ABC transporter (sugar-binding protein); SPTR: Sugar ABC transporter (Sugar-binding protein); PFAM: family; sugar ABC transporter periplasmic protein complement(3721739..3722686) Spirochaeta smaragdinae DSM 11293 9491584 YP_003805143.1 CDS Spirs_3461 NC_014364.1 3723487 3725040 R KEGG: oih:OB0366 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3723487..3725040) Spirochaeta smaragdinae DSM 11293 9491585 YP_003805144.1 CDS Spirs_3462 NC_014364.1 3725075 3725887 R COGs: COG1082 Sugar phosphate isomerase/epimerase; InterPro IPR012307; KEGG: tnp:Tnap_0208 xylose isomerase domain protein TIM barrel; PFAM: Xylose isomerase domain protein TIM barrel; SPTR: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; xylose isomerase complement(3725075..3725887) Spirochaeta smaragdinae DSM 11293 9491586 YP_003805145.1 CDS Spirs_3463 NC_014364.1 3725933 3727051 R COGs: COG1402 Uncharacterized protein amidase; KEGG: tma:TM0413 creatinine amidohydrolase, SPTR: creatinine amidohydrolase; PFAM: Creatinine amidohydrolase; creatinine amidohydrolase complement(3725933..3727051) Spirochaeta smaragdinae DSM 11293 9491587 YP_003805146.1 CDS Spirs_3464 NC_014364.1 3727231 3728010 D COGs: COG2186 transcriptional regulators; InterPro IPR000524:IPR011711; KEGG: gka:GK2015 transcriptional regulator; PFAM: regulatory protein GntR HTH; GntR family transcriptional regulator; SMART: regulatory protein GntR HTH; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; FCD domain; regulatory protein GntR 3727231..3728010 Spirochaeta smaragdinae DSM 11293 9491588 YP_003805147.1 CDS Spirs_3465 NC_014364.1 3728061 3730163 D COGs: COG1523 type II secretory pathway pullulanase PulA and related glycosidase; InterPro IPR006589:IPR004193:IPR006047:IPR011837; KEGG: mca:MCA0296 glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase family 13 domain protein; alpha amylase catalytic region; SMART: alpha amylase catalytic sub domain; SPTR: glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: carbohydrate-binding module 48 (Isoamylase N-terminal domain); alpha amylase, catalytic domain; TIGRFAM: glycogen debranching enzyme GlgX; glycogen debranching protein GlgX 3728061..3730163 Spirochaeta smaragdinae DSM 11293 9491589 YP_003805148.1 CDS Spirs_3466 NC_014364.1 3730299 3730622 R InterPro IPR007712; KEGG: dhd:Dhaf_0570 plasmid stabilization system; PFAM: plasmid stabilization system; SPTR: Plasmid stabilization system; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family; plasmid stabilization system complement(3730299..3730622) Spirochaeta smaragdinae DSM 11293 9491590 YP_003805149.1 CDS Spirs_3467 NC_014364.1 3730625 3730912 R InterPro IPR003756:IPR006442; KEGG: cpb:Cphamn1_1669 prevent-host-death family protein; PFAM: protein of unknown function DUF172; SPTR: Prevent-host-death family protein; TIGRFAM: prevent-host-death family protein; PFAM: Phd_YefM; TIGRFAM: prevent-host-death family protein; prevent-host-death family protein complement(3730625..3730912) Spirochaeta smaragdinae DSM 11293 9491591 YP_003805150.1 CDS Spirs_3468 NC_014364.1 3731199 3731558 D COGs: COG0239 integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: dol:Dole_2979 camphor resistance protein CrcB; PFAM: Camphor resistance CrcB protein; SPTR: protein crcB homolog; TIGRFAM: CrcB protein; PFAM: CrcB-like protein; TIGRFAM: crcB protein; CrcB protein 3731199..3731558 Spirochaeta smaragdinae DSM 11293 9491592 YP_003805151.1 CDS Spirs_3469 NC_014364.1 3731569 3732810 D COGs: COG3448 CBS-domain-containing membrane protein; InterPro IPR000644:IPR003793; KEGG: dol:Dole_2980 signal transduction protein; PFAM: CBS domain containing protein; protein of unknown function DUF190; SMART: CBS domain containing protein; SPTR: signal transduction protein with CBS domains; PFAM: CBS domain; Uncharacterized ACR, COG1993; CBS domain containing membrane protein 3731569..3732810 Spirochaeta smaragdinae DSM 11293 9491593 YP_003805152.1 CDS Spirs_3470 NC_014364.1 3732855 3733940 R COGs: COG0502 Biotin synthase; InterPro IPR006638:IPR007197; KEGG: swo:Swol_1674 hypothetical protein; PFAM: radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: uncharacterized protein; PFAM: radical SAM superfamily; radical SAM protein complement(3732855..3733940) Spirochaeta smaragdinae DSM 11293 9491594 YP_003805153.1 CDS Spirs_3471 NC_014364.1 3733944 3735017 R COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: swo:Swol_1675 hypothetical protein; PFAM: periplasmic binding protein; SPTR: uncharacterized protein; PFAM: Periplasmic binding protein; periplasmic binding protein complement(3733944..3735017) Spirochaeta smaragdinae DSM 11293 9491595 YP_003805154.1 CDS Spirs_3472 NC_014364.1 3735113 3735871 R KEGG: tai:Taci_1616 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF364); hypothetical protein complement(3735113..3735871) Spirochaeta smaragdinae DSM 11293 9491596 YP_003805155.1 CDS Spirs_3473 NC_014364.1 3735890 3736582 R COGs: COG4149 ABC-type molybdate transporter permease; InterPro IPR000515; KEGG: dma:DMR_19540 molybdenum ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: Binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport system inner membrane component; binding-protein-dependent transporters inner membrane component complement(3735890..3736582) Spirochaeta smaragdinae DSM 11293 9491597 YP_003805156.1 CDS Spirs_3474 NC_014364.1 3736584 3737312 R COGs: COG0725 ABC-type molybdate transporter periplasmic component; InterPro IPR005950; KEGG: dma:DMR_19530 molybdenum ABC transporter substrate binding protein precursor; SPTR: Molybdenum ABC transporter periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; TIGRFAM: molybdenum ABC transporter periplasmic molybdate-binding protein; molybdenum ABC transporter periplasmic molybdate-binding protein complement(3736584..3737312) Spirochaeta smaragdinae DSM 11293 9491598 YP_003805157.1 CDS Spirs_3475 NC_014364.1 3737326 3738030 R COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: dma:DMR_19520 molybdenum ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: molybdenum ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(3737326..3738030) Spirochaeta smaragdinae DSM 11293 9491599 YP_003805158.1 CDS Spirs_3476 NC_014364.1 3738174 3738608 D InterPro IPR000835; KEGG: aoe:Clos_2679 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR-family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator 3738174..3738608 Spirochaeta smaragdinae DSM 11293 9491600 YP_003805159.1 CDS Spirs_3477 NC_014364.1 3738605 3740350 D COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR001140:IPR003439:IPR017871:IPR 017940; KEGG: ttr:Tter_2351 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter 3738605..3740350 Spirochaeta smaragdinae DSM 11293 9491601 YP_003805160.1 CDS Spirs_3478 NC_014364.1 3740343 3742184 D COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR001140:IPR003439:IPR017871:IPR 017940; KEGG: ctc:CTC00426 multidrug resistance ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter; SMART: AAA ATPase; SPTR: Multidrug resistance ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter transmembrane protein 3740343..3742184 Spirochaeta smaragdinae DSM 11293 9491602 YP_003805161.1 CDS Spirs_3479 NC_014364.1 3742433 3743572 D InterPro IPR000014:IPR000792:IPR013656:IPR000700; KEGG: sat:SYN_02593 GerE family transcriptional regulator; PFAM: regulatory protein LuxR; hypothetical protein; SMART: regulatory protein LuxR; PAS domain containing protein; SPTR: transcriptional regulator GerE family; TIGRFAM: PAS sensor protein; PFAM: Bacterial regulatory proteins, luxR family; PAS fold; TIGRFAM: PAS domain S-box; LuxR family transcriptional regulator 3742433..3743572 Spirochaeta smaragdinae DSM 11293 9491603 YP_003805162.1 CDS Spirs_3480 NC_014364.1 3743693 3745648 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010:IPR016160; KEGG: dsa:Desal_3035 methyl-accepting chemotaxis sensory transducer; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 3743693..3745648 Spirochaeta smaragdinae DSM 11293 9491604 YP_003805163.1 CDS Spirs_3481 NC_014364.1 3745661 3746188 D COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: gsu:GSU0684 purine-binding chemotaxis protein CheW; PFAM: CheW domain protein; SMART: CheW domain protein; SPTR: Purine-binding chemotaxis protein CheW; PFAM: CheW-like domain; chemotaxis protein CheW 3745661..3746188 Spirochaeta smaragdinae DSM 11293 9491605 YP_003805164.1 CDS Spirs_3482 NC_014364.1 3746207 3747355 R COGs: COG1929 glycerate kinase; InterPro IPR004381; KEGG: chy:CHY_1268 glycerate kinase 2; PFAM: glycerate kinase; PRIAM: glycerate kinase; SPTR: glycerate kinase 2; TIGRFAM: glycerate kinase; PFAM: glycerate kinase family; TIGRFAM: glycerate kinase; glycerate kinase complement(3746207..3747355) Spirochaeta smaragdinae DSM 11293 9491606 YP_003805165.1 CDS Spirs_3483 NC_014364.1 3747373 3748206 R COGs: COG1237 metal-dependent hydrolase of the beta-lactamase superfamily II; KEGG: cbk:CLL_A2950 beta-lactamase domain protein; SPTR: beta-lactamase; manually curated; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(3747373..3748206) Spirochaeta smaragdinae DSM 11293 9491607 YP_003805166.1 CDS Spirs_3484 NC_014364.1 3748304 3749437 R COGs: COG0136 aspartate-semialdehyde dehydrogenase; InterProIPR000534:IPR012280:IPR000319:IPR012080:IPR 005676; KEGG: tro:trd_0366 aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase dimerisation region; semialdehyde dehydrogenase NAD - binding; PRIAM: aspartate-semialdehyde dehydrogenase; SPTR: aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (non-peptidoglycan organisms); aspartate-semialdehyde dehydrogenase complement(3748304..3749437) Spirochaeta smaragdinae DSM 11293 9491608 YP_003805167.1 CDS Spirs_3485 NC_014364.1 3749689 3750435 R InterPro IPR003675; KEGG: pfs:PFLU3455 hypothetical protein; PFAM: hypothetical protein; SPTR: membrane protein; PFAM: CAAX amino terminal protease family; hypothetical protein complement(3749689..3750435) Spirochaeta smaragdinae DSM 11293 9491609 YP_003805168.1 CDS Spirs_3486 NC_014364.1 3750541 3750909 D COGs: COG0640 transcriptional regulator protein; InterPro IPR001845:IPR018334; KEGG: mta:Moth_2202 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR; SPTR: ArsR family transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family; ArsR family transcriptional regulator 3750541..3750909 Spirochaeta smaragdinae DSM 11293 9491610 YP_003805169.1 CDS Spirs_3487 NC_014364.1 3750917 3752923 D COGs: COG2217 Cation transport ATPase; InterProIPR008250:IPR005834:IPR018303:IPR001757:IPR 000695:IPR006404:IPR006416; KEGG: ddf:DEFDS_0300 heavy-metal transporting P-type ATPase; PFAM: E1-E2 ATPase-associated domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Heavy-metal transporting P-type ATPase; TIGRFAM: ATPase P; cadmium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase P; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; ATPase P 3750917..3752923 Spirochaeta smaragdinae DSM 11293 9491611 YP_003805170.1 CDS Spirs_3488 NC_014364.1 3752974 3753963 D COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR016160; KEGG: pmx:PERMA_0097 signal transduction response regulator; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Signal transduction response regulator; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase 3752974..3753963 Spirochaeta smaragdinae DSM 11293 9491612 YP_003805171.1 CDS Spirs_3489 NC_014364.1 3754010 3754693 D COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: cth:Cthe_3048 DNA repair protein RadC; PFAM: DNA repair protein RadC; SPTR: DNA repair protein; TIGRFAM: DNA repair protein RadC; PFAM: protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; DNA repair protein RadC 3754010..3754693 Spirochaeta smaragdinae DSM 11293 9491613 YP_003805172.1 CDS Spirs_3490 NC_014364.1 3754724 3756775 R COGs: COG0370 Fe2+ transporter protein B; InterProIPR002917:IPR011619:IPR011642:IPR011640:IPR 005225:IPR003373; KEGG: ckr:CKR_1889 hypothetical protein; PFAM: GTP-binding protein HSR1-related; Ferrous iron transporter B domain protein; nucleoside recognition domain protein; Ferrous iron transport B domain protein; SPTR: uncharacterized protein; TIGRFAM: ferrous iron transporter B; small GTP-binding protein; PFAM: Ferrous iron transporter B; Ferrous iron transporter B C terminus; nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB; small GTP-binding protein domain; ferrous iron transporter B complement(3754724..3756775) Spirochaeta smaragdinae DSM 11293 9491614 YP_003805173.1 CDS Spirs_3491 NC_014364.1 3756776 3757003 R InterPro IPR007167; KEGG: smr:Smar_1579 FeoA family protein; PFAM: FeoA family protein; SPTR: FeoA family protein; PFAM: FeoA domain; FeoA family protein complement(3756776..3757003) Spirochaeta smaragdinae DSM 11293 9491615 YP_003805174.1 CDS Spirs_3492 NC_014364.1 3757069 3757374 R KEGG: sma:SAV_6558 MarR family transcriptional regulator; SPTR: MarR-family transcriptional regulator; hypothetical protein complement(3757069..3757374) Spirochaeta smaragdinae DSM 11293 9491616 YP_003805175.1 CDS Spirs_3493 NC_014364.1 3757361 3758713 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cbl:CLK_2227 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(3757361..3758713) Spirochaeta smaragdinae DSM 11293 9491617 YP_003805176.1 CDS Spirs_3494 NC_014364.1 3758729 3760483 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR003593:IPR003439:IPR017871:IPR017940; KEGG: dsy:DSY4742 hypothetical protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3758729..3760483) Spirochaeta smaragdinae DSM 11293 9491618 YP_003805177.1 CDS Spirs_3495 NC_014364.1 3760476 3762251 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR001140:IPR003439:IPR017871:IPR 017940; KEGG: dhd:Dhaf_4629 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3760476..3762251) Spirochaeta smaragdinae DSM 11293 9491619 YP_003805178.1 CDS Spirs_3496 NC_014364.1 3762290 3762907 R InterPro IPR001647; KEGG: dsy:DSY4740 hypothetical protein; PFAM: regulatory protein TetR; SPTR: uncharacterized protein; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(3762290..3762907) Spirochaeta smaragdinae DSM 11293 9491620 YP_003805179.1 CDS Spirs_3497 NC_014364.1 3763161 3764492 D COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002293; KEGG: dsa:Desal_3806 amino acid permease-associated region; PFAM: amino acid permease-associated region; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; amino acid permease-associated protein 3763161..3764492 Spirochaeta smaragdinae DSM 11293 9491621 YP_003805180.1 CDS Spirs_3498 NC_014364.1 3764510 3765286 D InterPro IPR000792; KEGG: sat:SYN_01476 LuxR family regulatory protein; PFAM: regulatory protein LuxR; SMART: regulatory protein LuxR; SPTR: Bacterial regulatory protein, LuxR family; PFAM: Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 3764510..3765286 Spirochaeta smaragdinae DSM 11293 9491622 YP_003805181.1 CDS Spirs_3499 NC_014364.1 3765375 3765770 D KEGG: azl:AZL_d04670 regulator of nucleoside diphosphate kinase; SPTR: Regulator of nucleoside diphosphate kinase; PFAM: transcription elongation factor, GreA/GreB, C-term; GreA/GreB family elongation factor 3765375..3765770 Spirochaeta smaragdinae DSM 11293 9491623 YP_003805182.1 CDS Spirs_3500 NC_014364.1 3765795 3766781 D KEGG: tde:TDE1725 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3765795..3766781 Spirochaeta smaragdinae DSM 11293 9491624 YP_003805183.1 CDS Spirs_3501 NC_014364.1 3766760 3770008 R COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR014016:IPR014017; KEGG: rmr:Rmar_0317 UvrD/REP helicase; PFAM: UvrD/REP helicase; SPTR: UvrD/REP helicase; PFAM: UvrD/REP helicase; TIGRFAM: conserved hypothetical protein TIGR00375; UvrD/REP helicase complement(3766760..3770008) Spirochaeta smaragdinae DSM 11293 9491625 YP_003805184.1 CDS Spirs_3502 NC_014364.1 3770106 3771164 D COGs: COG3180 ammonia monooxygenase; InterPro IPR007820:IPR017516; KEGG: tau:Tola_1805 membrane protein AbrB duplication; PFAM: ammonia monooxygenase; SPTR: ammonia monooxygenase; TIGRFAM: membrane protein AbrB duplication; PFAM: ammonia monooxygenase; TIGRFAM: membrane protein AbrB duplication; membrane protein 3770106..3771164 Spirochaeta smaragdinae DSM 11293 9491626 YP_003805185.1 CDS Spirs_3503 NC_014364.1 3771238 3771624 R COGs: COG3576 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase; InterPro IPR011576; KEGG: mtp:Mthe_1045 pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: pyridoxamine 5'-phosphate oxidase-related FMN-binding; SPTR: pyridoxamine 5'-phosphate oxidase-related, FMN-binding; PFAM: pyridoxamine 5'-phosphate oxidase; pyridoxamine 5'-phosphate oxidase-like FMN-binding protein complement(3771238..3771624) Spirochaeta smaragdinae DSM 11293 9491627 YP_003805186.1 CDS Spirs_3504 NC_014364.1 3771810 3772277 R COGs: COG0054 riboflavin synthase beta-chain; InterPro IPR002180; KEGG: apa:APP7_0409 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 67-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; 6,7-dimethyl-8-ribityllumazine synthase complement(3771810..3772277) Spirochaeta smaragdinae DSM 11293 9491628 YP_003805187.1 CDS Spirs_3505 NC_014364.1 3772274 3772933 R COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR000422:IPR010916; KEGG: tai:Taci_1008 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 34-dihydroxy-2-butanone 4-phosphate synthase; SPTR: 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(3772274..3772933) Spirochaeta smaragdinae DSM 11293 9491629 YP_003805188.1 CDS Spirs_3506 NC_014364.1 3772934 3773560 R COGs: COG0307 riboflavin synthase alpha chain; InterPro IPR001783; KEGG: sul:SYO3AOP1_0177 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: riboflavin synthase; SPTR: riboflavin synthase, subunit alpha; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, subunit alpha; riboflavin synthase complement(3772934..3773560) Spirochaeta smaragdinae DSM 11293 9491630 YP_003805189.1 CDS Spirs_3507 NC_014364.1 3774171 3775307 R COGs: COG0719 ABC-type transporter involved in Fe-S cluster assembly permease; InterPro IPR000825; KEGG: gur:Gura_2451 SufBD protein; PFAM: SufBD protein; SPTR: SufBD protein; PFAM: Uncharacterized protein family (UPF0051); SufBD protein complement(3774171..3775307) Spirochaeta smaragdinae DSM 11293 9491631 YP_003805190.1 CDS Spirs_3508 NC_014364.1 3775291 3776043 R COGs: COG0396 ABC-type transporter involved in Fe-S cluster assembly ATPase component; InterPro IPR003439; KEGG: mae:Maeo_0319 ABC transporter related; PFAM: ABC transporter; SPTR: ABC transporter related; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC; ABC transporter complement(3775291..3776043) Spirochaeta smaragdinae DSM 11293 9491632 YP_003805191.1 CDS Spirs_3509 NC_014364.1 3776079 3776516 R InterPro IPR000835; KEGG: cac:CAC0559 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator complement(3776079..3776516) Spirochaeta smaragdinae DSM 11293 9491633 YP_003805192.1 CDS Spirs_3510 NC_014364.1 3776735 3777352 D COGs: COG0522 ribosomal protein S4 and related protein; InterPro IPR002942:IPR001912:IPR018079:IPR005709; KEGG: tde:TDE1943 30S ribosomal protein S4; PFAM: ribosomal protein S4; RNA-binding S4 domain protein; SMART: RNA-binding S4 domain protein; SPTR: 30S ribosomal protein S4; TIGRFAM: ribosomal protein S4; PFAM: ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type; 30S ribosomal protein S4 3776735..3777352 Spirochaeta smaragdinae DSM 11293 9491634 YP_003805193.1 CDS Spirs_3511 NC_014364.1 3777481 3778368 D COGs: COG3588 fructose-1 6-bisphosphate aldolase; InterPro IPR000741; KEGG: fjo:Fjoh_0953 fructose-1,6-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I; SPTR: fructose-bisphosphate aldolase; PFAM: fructose-bisphosphate aldolase class-I; fructose-bisphosphate aldolase class-I 3777481..3778368 Spirochaeta smaragdinae DSM 11293 9491635 YP_003805194.1 CDS Spirs_3512 NC_014364.1 3778437 3780170 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR001140:IPR003439:IPR017871:IPR 017940; KEGG: pgn:PGN_1916 ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3778437..3780170) Spirochaeta smaragdinae DSM 11293 9491636 YP_003805195.1 CDS Spirs_3513 NC_014364.1 3780172 3781971 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR003593:IPR001140:IPR003439:IPR017871:IPR 017940; KEGG: pgn:PGN_1917 ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(3780172..3781971) Spirochaeta smaragdinae DSM 11293 9491637 YP_003805196.1 CDS Spirs_3514 NC_014364.1 3782256 3782720 D InterPro IPR000835; KEGG: tde:TDE0259 MarR family transcriptional regulator; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator 3782256..3782720 Spirochaeta smaragdinae DSM 11293 9491638 YP_003805197.1 CDS Spirs_3515 NC_014364.1 3782717 3783595 D InterPro IPR001450:IPR017900:IPR017896; KEGG: tde:TDE0260 iron-sulfur cluster-binding protein; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: 4Fe-4S binding domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein 3782717..3783595 Spirochaeta smaragdinae DSM 11293 9491639 YP_003805198.1 CDS Spirs_3516 NC_014364.1 3783595 3784230 D COGs: COG2910 NADH-flavin reductase; KEGG: cpi:Cpin_3281 NAD-dependent epimerase/dehydratase; SPTR: NAD-dependent epimerase/dehydratase; PFAM: NmrA-like family; NAD-dependent epimerase/dehydratase 3783595..3784230 Spirochaeta smaragdinae DSM 11293 9491640 YP_003805199.1 CDS Spirs_3517 NC_014364.1 3784262 3785149 R COGs: COG0583 transcriptional regulator; InterPro IPR000847; KEGG: dal:Dalk_5021 chromosome replication initiation inhibitor protein; PFAM: regulatory protein LysR; SPTR: transcriptional regulator, ArgP, LysR family; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; TIGRFAM: transcriptional regulator, ArgP family; LysR family transcriptional regulator complement(3784262..3785149) Spirochaeta smaragdinae DSM 11293 9491641 YP_003805200.1 CDS Spirs_3518 NC_014364.1 3785255 3787480 D COGs: COG1882 pyruvate-formate lyase; InterPro IPR004184:IPR001150:IPR019777:IPR005949; KEGG: cyc:PCC7424_2838 formate acetyltransferase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: formate C-acetyltransferase; SPTR: formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: glycine radical; pyruvate formate lyase; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; formate acetyltransferase 1; formate acetyltransferase 3785255..3787480 Spirochaeta smaragdinae DSM 11293 9491642 YP_003805201.1 CDS Spirs_3519 NC_014364.1 3787496 3788233 D COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterPro IPR007197:IPR001989:IPR012838; KEGG: cyb:CYB_0243 pyruvate formate-lyase activating enzyme; PFAM: radical SAM protein; PRIAM: [formate-C-acetyltransferase]-activating enzyme; SPTR: pyruvate formate-lyase activating enzyme; TIGRFAM: pyruvate formate-lyase activating enzyme; PFAM: radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme; pyruvate formate-lyase activating enzyme 3787496..3788233 Spirochaeta smaragdinae DSM 11293 9491643 YP_003805202.1 CDS Spirs_3520 NC_014364.1 3788456 3789076 D KEGG: cau:Caur_1651 GAF domain-containing protein; SPTR: GAF domain protein; hypothetical protein 3788456..3789076 Spirochaeta smaragdinae DSM 11293 9491644 YP_003805203.1 CDS Spirs_3521 NC_014364.1 3789061 3789321 R KEGG: saq:Sare_3766 HK97 family phage prohead protease; SPTR: 30S ribosomal protein S3, chloroplastic; hypothetical protein complement(3789061..3789321) Spirochaeta smaragdinae DSM 11293 9491645 YP_003805204.1 CDS Spirs_3522 NC_014364.1 3789420 3790211 R COGs: COG0647 sugar phosphatase of the HAD superfamily; InterPro IPR005834:IPR006357; KEGG: fnu:FN1255 NagD protein; PFAM: haloacid dehalogenase; SPTR: NagD protein; TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; TIGRFAM: HAD-superfamily subfamily IIA hydrolase, TIGR01457; phosphoglycolate/pyridoxal phosphate phosphatase family; Haloacid Dehalogenase Superfamily class (subfamily) IIA; HAD-superfamily hydrolase complement(3789420..3790211) Spirochaeta smaragdinae DSM 11293 9491646 YP_003805205.1 CDS Spirs_3523 NC_014364.1 3790239 3791525 R COGs: COG1593 TRAP-type C4-dicarboxylate transporter large permease; InterPro IPR010656:IPR004681; KEGG: fnu:FN1256 C4-dicarboxylate transporter large subunit; PFAM: TRAP C4-dicarboxylate transporter permease DctM subunit; SPTR: C4-dicarboxylate transporter large subunit; TIGRFAM: TRAP dicarboxylate transporter DctM subunit; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter DctM subunit; TRAP dicarboxylate transporter subunit DctM complement(3790239..3791525) Spirochaeta smaragdinae DSM 11293 9491647 YP_003805206.1 CDS Spirs_3524 NC_014364.1 3791527 3792021 R COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: fnu:FN1257 C4-dicarboxylate transporter small subunit; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: C4-dicarboxylate transporter small subunit; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ component complement(3791527..3792021) Spirochaeta smaragdinae DSM 11293 9491648 YP_003805207.1 CDS Spirs_3525 NC_014364.1 3792120 3793265 R COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389; KEGG: fnu:FN1258 C4-dicarboxylate-binding protein; PFAM: extracellular solute-binding protein, family 7; SPTR: C4-dicarboxylate-binding protein; PFAM: Bacterial extracellular solute-binding protein, family 7; extracellular solute-binding protein, family 7 complement(3792120..3793265) Spirochaeta smaragdinae DSM 11293 9491649 YP_003805208.1 CDS Spirs_3526 NC_014364.1 3793553 3793768 D InterPro IPR006121:IPR017969:IPR001802; KEGG: cco:CCC13826_2066 mercuric transporter periplasmic component; PFAM: Heavy metal transport/detoxification protein; SPTR: Mercuric transporter periplasmic component (Periplasmic mercury ion-binding protein) (Mercury scavenger protein); PFAM: Heavy-metal-associated domain; Heavy metal transport/detoxification protein 3793553..3793768 Spirochaeta smaragdinae DSM 11293 9491650 YP_003805209.1 CDS Spirs_3527 NC_014364.1 3793921 3794649 D InterPro IPR013216; KEGG: dsy:DSY3212 hypothetical protein; PFAM: methyltransferase type 11; SPTR: uncharacterized protein; PFAM: methyltransferase domain; type 11 methyltransferase 3793921..3794649 Spirochaeta smaragdinae DSM 11293 9491651 YP_003805210.1 CDS Spirs_3528 NC_014364.1 3794687 3795703 R InterPro IPR013217:IPR010916; KEGG: dae:Dtox_2658 O-methyltransferase family 2; PFAM: methyltransferase type 12; SPTR: uncharacterized protein; PFAM: O-methyltransferase; type 12 methyltransferase complement(3794687..3795703) Spirochaeta smaragdinae DSM 11293 9491652 YP_003805211.1 CDS Spirs_3529 NC_014364.1 3795718 3796074 R KEGG: apo:Arcpr_0152 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3795718..3796074) Spirochaeta smaragdinae DSM 11293 9491653 YP_003805212.1 CDS Spirs_3530 NC_014364.1 3796124 3797272 R InterPro IPR013217; KEGG: dae:Dtox_2658 O-methyltransferase family 2; PFAM: methyltransferase type 12; SPTR: O-methyltransferase family 2; PFAM: O-methyltransferase; type 12 methyltransferase complement(3796124..3797272) Spirochaeta smaragdinae DSM 11293 9491654 YP_003805213.1 CDS Spirs_3531 NC_014364.1 3797324 3798178 R COGs: COG1176 ABC-type spermidine/putrescine transport system permease I; InterPro IPR000515; KEGG: clo:HMPREF0868_0379 ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter permease protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3797324..3798178) Spirochaeta smaragdinae DSM 11293 9491655 YP_003805214.1 CDS Spirs_3532 NC_014364.1 3798253 3799428 R COGs: COG4134 ABC-type uncharacterized transporter periplasmic component; InterPro IPR006059; KEGG: clo:HMPREF0868_0378 bacterial extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: Bacterial extracellular solute-binding protein; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(3798253..3799428) Spirochaeta smaragdinae DSM 11293 9491656 YP_003805215.1 CDS Spirs_3533 NC_014364.1 3799480 3800460 R COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR003593:IPR003439:IPR013611:IPR017871; KEGG: clo:HMPREF0868_0377 ABC transporter ATP-binding protein; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain; ABC transporter complement(3799480..3800460) Spirochaeta smaragdinae DSM 11293 9491657 YP_003805216.1 CDS Spirs_3534 NC_014364.1 3800495 3801367 R COGs: COG1177 ABC-type spermidine/putrescine transport system permease II; InterPro IPR000515; KEGG: clo:HMPREF0868_0376 ABC transporter permease; PFAM: binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter permease protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3800495..3801367) Spirochaeta smaragdinae DSM 11293 9491658 YP_003805217.1 CDS Spirs_3535 NC_014364.1 3801376 3802137 R COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: clo:HMPREF0868_0382 hypothetical protein; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase family; glycerophosphoryl diester phosphodiesterase complement(3801376..3802137) Spirochaeta smaragdinae DSM 11293 9491659 YP_003805218.1 CDS Spirs_3536 NC_014364.1 3802296 3803294 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761:IPR000394; KEGG: pjd:Pjdr2_2899 transcriptional regulator, LacI family; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 3802296..3803294 Spirochaeta smaragdinae DSM 11293 9491660 YP_003805219.1 CDS Spirs_3537 NC_014364.1 3803338 3806568 R COGs: COG0458 carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005481:IPR005479:IPR005480:IPR011607:IPR 005483:IPR006275:IPR011761; KEGG: gdj:Gdia_3031 carbamoyl phosphate synthase large subunit; PFAM: carbamoyl-phosphate synthase L chain ATP-binding; carbamoyl-phosphate synthetase large chain domain protein; carbamoyl-phosphate synthetase large chain oligomerisation; MGS domain protein; SPTR: carbamoyl-phosphate synthase, large subunit; TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; carbamoyl-phosphate synthetase large chain, oligomerisation domain; carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; carbamoyl-phosphate synthase, large subunit complement(3803338..3806568) Spirochaeta smaragdinae DSM 11293 9491661 YP_003805220.1 CDS Spirs_3538 NC_014364.1 3806565 3807761 R COGs: COG0505 carbamoylphosphate synthase small subunit; InterProIPR002474:IPR000991:IPR001317:IPR011702:IPR 006220:IPR006274:IPR017926; KEGG: chl:Chy400_0938 carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; carbamoyl-phosphate synthase small chain; SPTR: carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: carbamoyl-phosphate synthase small chain, CPSase domain; glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; carbamoyl-phosphate synthase, small subunit complement(3806565..3807761) Spirochaeta smaragdinae DSM 11293 9491662 YP_003805221.1 CDS Spirs_3539 NC_014364.1 3808017 3810188 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR001789:IPR000014:IPR001610:IPR013655:IPR 013767:IPR011495:IPR003594:IPR005467:IPR000700:IPR001385; KEGG: cyn:Cyan7425_4138 signal transduction histidine kinase; PFAM: PAS fold-3 domain protein; response regulator receiver; PAS fold domain protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: response regulator receiver; PAS domain containing protein; PAC repeat-containing protein; SPTR: Signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 3808017..3810188 Spirochaeta smaragdinae DSM 11293 9491663 YP_003805222.1 CDS Spirs_3540 NC_014364.1 3810229 3812127 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR000014:IPR003661:IPR003594:IPR001789:IPR 013656:IPR013655:IPR004358:IPR005467; KEGG: lbf:LBF_0869 sensor histidine kinase and response regulator of a two component complex; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold-3 domain protein; response regulator receiver; SMART: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor hybrid histidine kinase 3810229..3812127 Spirochaeta smaragdinae DSM 11293 9491664 YP_003805223.1 CDS Spirs_3541 NC_014364.1 3812192 3813694 R COGs: COG0554 glycerol kinase; InterPro IPR018484:IPR018485:IPR018483:IPR005999; KEGG: aoe:Clos_1002 glycerol kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: glycerol kinase; TIGRFAM: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; glycerol kinase complement(3812192..3813694) Spirochaeta smaragdinae DSM 11293 9491665 YP_003805224.1 CDS Spirs_3542 NC_014364.1 3813719 3814471 R COGs: COG0580 glycerol uptake facilitator and related permease (Major Intrinsic protein Family); InterPro IPR000425:IPR012269; KEGG: tex:Teth514_1019 MIP family channel protein; PFAM: major intrinsic protein; SPTR: MIP family channel protein; TIGRFAM: MIP family channel protein; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins; MIP family channel protein complement(3813719..3814471) Spirochaeta smaragdinae DSM 11293 9491666 YP_003805225.1 CDS Spirs_3543 NC_014364.1 3814942 3816453 D COGs: COG0579 dehydrogenase; InterPro IPR006076:IPR007419; KEGG: tpd:Teth39_0537 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD domain protein [2Fe-2S]-binding domain protein; SPTR: FAD dependent oxidoreductase; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; FAD dependent oxidoreductase 3814942..3816453 Spirochaeta smaragdinae DSM 11293 9491667 YP_003805226.1 CDS Spirs_3544 NC_014364.1 3816431 3817708 D COGs: COG1249 pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027; KEGG: amt:Amet_0974 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; FAD-dependent pyridine nucleotide-disulfide oxidoreductase 3816431..3817708 Spirochaeta smaragdinae DSM 11293 9491668 YP_003805227.1 CDS Spirs_3545 NC_014364.1 3817705 3818085 D COGs: COG3862 Uncharacterized protein with conserved CXXC pairs; InterPro IPR012460; KEGG: tnp:Tnap_1378 protein of unknown function DUF1667; PFAM: protein of unknown function DUF1667; SPTR: Uncharacterized protein with conserved CXXC pairs; PFAM: protein of unknown function (DUF1667); hypothetical protein 3817705..3818085 Spirochaeta smaragdinae DSM 11293 9491669 YP_003805228.1 CDS Spirs_3546 NC_014364.1 3818201 3819184 D COGs: COG2390 transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: ddr:Deide_2p00240 DeoR family transcriptional regulator; PFAM: sugar-binding domain protein; SPTR: DeoR family transcriptional regulator; PFAM: sugar-binding domain; DeoR family transcriptional regulator 3818201..3819184 Spirochaeta smaragdinae DSM 11293 9491670 YP_003805229.1 CDS Spirs_3547 NC_014364.1 3819256 3819726 D KEGG: ssp:SSP1352 peptidase; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport; hypothetical protein 3819256..3819726 Spirochaeta smaragdinae DSM 11293 9491671 YP_003805230.1 CDS Spirs_3548 NC_014364.1 3819760 3820695 R COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; KEGG: cbt:CLH_1640 hypothetical protein; SPTR: uncharacterized protein; PFAM: RibD C-terminal domain; hypothetical protein complement(3819760..3820695) Spirochaeta smaragdinae DSM 11293 9491672 YP_003805231.1 CDS Spirs_3549 NC_014364.1 3820764 3820997 R KEGG: sth:STH3130 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF3343); hypothetical protein complement(3820764..3820997) Spirochaeta smaragdinae DSM 11293 9491673 YP_003805232.1 CDS Spirs_3550 NC_014364.1 3820994 3822199 R COGs: COG0520 Selenocysteine lyase; InterPro IPR000192:IPR020578:IPR010969; KEGG: sth:STH3131 cysteine desulfurase; PFAM: aminotransferase class V; SPTR: cysteine desulfurase; TIGRFAM: cysteine desulfurase family protein; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein; cysteine desulfurase family protein complement(3820994..3822199) Spirochaeta smaragdinae DSM 11293 9491674 YP_003805233.1 CDS Spirs_3551 NC_014364.1 3822199 3822417 R InterPro IPR001455; KEGG: tai:Taci_0248 hypothetical protein; PFAM: SirA family protein; SPTR: uncharacterized protein; PFAM: SirA-like protein; SirA family protein complement(3822199..3822417) Spirochaeta smaragdinae DSM 11293 9491675 YP_003805234.1 CDS Spirs_3552 NC_014364.1 3822419 3823531 R KEGG: pca:Pcar_0820 hypothetical protein; SPTR: uncharacterized protein; PFAM: YeeE/YedE family (DUF395); hypothetical protein complement(3822419..3823531) Spirochaeta smaragdinae DSM 11293 9491676 YP_003805235.1 CDS Spirs_3553 NC_014364.1 3823880 3824455 D COGs: COG1971 membrane protein; InterPro IPR003810; KEGG: dvl:Dvul_0455 hypothetical protein; PFAM: protein of unknown function DUF204; SPTR: uncharacterized protein; manually curated; PFAM: Domain of unknown function DUF; hypothetical protein 3823880..3824455 Spirochaeta smaragdinae DSM 11293 9491677 YP_003805236.1 CDS Spirs_3554 NC_014364.1 3824437 3826494 R COGs: COG3711 transcriptional antiterminator; InterPro IPR013196; KEGG: gyc:GYMC61_2796 PTS modulated transcriptional regulator, MtlR family; PFAM: hypothetical protein; SPTR: PTS modulated transcriptional regulator, MtlR family; PFAM: HTH domain; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; transcriptional antiterminator BglG complement(3824437..3826494) Spirochaeta smaragdinae DSM 11293 9491678 YP_003805237.1 CDS Spirs_3555 NC_014364.1 3826491 3828212 R COGs: COG1080 phosphoenolpyruvate-protein kinase (PTS system EI component); InterProIPR008731:IPR008279:IPR000121:IPR018274:IPR 006318; KEGG: hde:HDEF_0323 PTS family enzyme I and HPr components, PEP-protein phosphotransferase; PFAM: PEP-utilizing protein; PEP-utilising protein mobile region; PEP-utilising protein domain protein; SPTR: PTS family enzyme I and Hpr components, PEP-protein phosphotransferase; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; phosphoenolpyruvate-protein phosphotransferase complement(3826491..3828212) Spirochaeta smaragdinae DSM 11293 9491679 YP_003805238.1 CDS Spirs_3556 NC_014364.1 3828209 3828484 R COGs: COG1925 phosphotransferase system HPr-related protein; InterPro IPR005698:IPR001020:IPR000032; KEGG: sth:STH3280 PTS system phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: PTS family porter component HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: phosphotransferase System HPr (HPr) Family; phosphotransferase system, phosphocarrier protein HPr complement(3828209..3828484) Spirochaeta smaragdinae DSM 11293 9491680 YP_003805239.1 CDS Spirs_3557 NC_014364.1 3828510 3829460 R COGs: COG1105 fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR002173; KEGG: edi:EDI_134140 Tagatose-6-phosphate kinase; PFAM: PfkB domain protein; SPTR: Tagatose-6-phosphate kinase, ; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(3828510..3829460) Spirochaeta smaragdinae DSM 11293 9491681 YP_003805240.1 CDS Spirs_3558 NC_014364.1 3829460 3830734 R COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013149; KEGG: csc:Csac_0869 alcohol dehydrogenase; PFAM: alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase, zinc-binding domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(3829460..3830734) Spirochaeta smaragdinae DSM 11293 9491682 YP_003805241.1 CDS Spirs_3559 NC_014364.1 3830731 3831216 R COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: etr:ETAE_3294 L-ascorbate-specific enzyme IIA component of PTS; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: L-ascorbate-specific enzyme IIA component of PTS; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS IIA-like nitrogen-regulatory protein PtsN complement(3830731..3831216) Spirochaeta smaragdinae DSM 11293 9491683 YP_003805242.1 CDS Spirs_3560 NC_014364.1 3831303 3832685 R COGs: COG2213 phosphotransferase system mannitol-specific IIBC component; InterProIPR003352:IPR003501:IPR004718:IPR013011:IPR 013014; KEGG: amt:Amet_4271 PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system lactose/cellobiose-specific IIsubunit beta; phosphotransferase system EIIC; PRIAM: protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, mannitol-specific IIC subunit; TIGRFAM: PTS system, mannitol-specific IIC subunit; PFAM: phosphotransferase system, EIIC; PTS system, Lactose/cellobiose specific IIsubunit beta; TIGRFAM: PTS system, mannitol-specific IIC component; PTS system, mannitol-specific IIC subunit complement(3831303..3832685) Spirochaeta smaragdinae DSM 11293 9491684 YP_003805243.1 CDS Spirs_3561 NC_014364.1 3832859 3833827 R COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: sli:Slin_3046 aldose 1-epimerase; PFAM: aldose 1-epimerase; SPTR: aldose 1-epimerase; PFAM: aldose 1-epimerase; aldose 1-epimerase complement(3832859..3833827) Spirochaeta smaragdinae DSM 11293 9491685 YP_003805244.1 CDS Spirs_3562 NC_014364.1 3833824 3834600 R COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: ace:Acel_0374 LmbE family protein; PFAM: LmbE family protein; SPTR: LmbE family protein; PFAM: GlcNAc-PI de-N-acetylase; LmbE family protein complement(3833824..3834600) Spirochaeta smaragdinae DSM 11293 9491686 YP_003805245.1 CDS Spirs_3563 NC_014364.1 3834597 3835616 R COGs: COG2222 phosphosugar isomerase; InterPro IPR001347; KEGG: azl:AZL_b05010 glucosamine--fructose-6-phosphate aminotransferase (isomerizing); PFAM: sugar isomerase (SIS); SPTR: Predicted phosphosugar isomerase; PFAM: SIS domain; sugar isomerase (SIS) complement(3834597..3835616) Spirochaeta smaragdinae DSM 11293 9491687 YP_003805246.1 CDS Spirs_3564 NC_014364.1 3835666 3836847 R COGs: COG0205 6-phosphofructokinase; InterPro IPR000023:IPR011404; KEGG: ttr:Tter_0679 phosphofructokinase; PFAM: phosphofructokinase; SPTR: 6-phosphofructokinase; PFAM: phosphofructokinase; phosphofructokinase complement(3835666..3836847) Spirochaeta smaragdinae DSM 11293 9491688 YP_003805247.1 CDS Spirs_3565 NC_014364.1 3836837 3837823 R KEGG: cai:Caci_2491 ROK family protein; SPTR: ROK family protein; PFAM: ROK family; hypothetical protein complement(3836837..3837823) Spirochaeta smaragdinae DSM 11293 9491689 YP_003805248.1 CDS Spirs_3566 NC_014364.1 3837944 3839650 D COGs: COG2414 aldehyde:ferredoxin oxidoreductase; InterPro IPR013983; KEGG: dat:HRM2_02020 Aor1; SMART: aldehyde ferredoxin oxidoreductase; SPTR: Aor1; PFAM: aldehyde ferredoxin oxidoreductase, N-terminal domain; aldehyde ferredoxin oxidoreductase, domains 2 & 3; aldehyde ferredoxin oxidoreductase 3837944..3839650 Spirochaeta smaragdinae DSM 11293 9491690 YP_003805249.1 CDS Spirs_3567 NC_014364.1 3839915 3840349 D COGs: COG0394 protein-tyrosine-phosphatase; InterPro IPR017867; KEGG: dap:Dacet_2115 protein-tyrosine phosphatase, low molecular weight; PFAM: protein-tyrosine phosphatase, low molecular weight; SMART: protein-tyrosine phosphatase, low molecular weight; SPTR: protein-tyrosine phosphatase, low molecular weight; PFAM: Low molecular weight phosphotyrosine protein phosphatase; protein-tyrosine phosphatase, low molecular weight 3839915..3840349 Spirochaeta smaragdinae DSM 11293 9491692 YP_003805250.1 CDS Spirs_3568 NC_014364.1 3840325 3842169 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR000014:IPR001610:IPR000160:IPR013655; KEGG: pmo:Pmob_1834 diguanylate cyclase with PAS/PAC sensor; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: GGDEF domain containing protein; PAC repeat-containing protein; PAS domain containing protein; SPTR: Diguanylate cyclase with PAS/PAC sensor; TIGRFAM: diguanylate cyclase; PAS sensor protein; PFAM: GGDEF domain; PAS fold; TIGRFAM: PAS domain S-box; diguanylate cyclase (GGDEF) domain; PAS/PAC sensor-containing diguanylate cyclase complement(3840325..3842169) Spirochaeta smaragdinae DSM 11293 9491693 YP_003805251.1 CDS Spirs_3569 NC_014364.1 3842250 3842642 R InterPro IPR013766:IPR017936; KEGG: cts:Ctha_2208 thioredoxin domain; PFAM: thioredoxin domain; SPTR: thioredoxin domain; PFAM: thioredoxin; thioredoxin complement(3842250..3842642) Spirochaeta smaragdinae DSM 11293 9491694 YP_003805252.1 CDS Spirs_3570 NC_014364.1 3842706 3843749 D COGs: COG0123 Deacetylase including yeast histone deacetylase and acetoin utilization protein; InterPro IPR000286; KEGG: cti:RALTA_A1299 histone deacetylase; PFAM: histone deacetylase superfamily; SPTR: histone deacetylase/AcuC/AphA family protein; PFAM: histone deacetylase domain; histone deacetylase superfamily protein 3842706..3843749 Spirochaeta smaragdinae DSM 11293 9491695 YP_003805253.1 CDS Spirs_3571 NC_014364.1 3843808 3844137 R KEGG: cwo:Cwoe_0215 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3843808..3844137) Spirochaeta smaragdinae DSM 11293 9491696 YP_003805254.1 CDS Spirs_3572 NC_014364.1 3844127 3845218 R COGs: COG1162 GTPase; InterPro IPR004881:IPR010914; KEGG: gym:GYMC10_5999 GTPase EngC; PFAM: GTPase EngC; SPTR: GTPase EngC; TIGRFAM: ribosome small subunit-dependent GTPase A; PFAM: protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A; ribosome small subunit-dependent GTPase A complement(3844127..3845218) Spirochaeta smaragdinae DSM 11293 9491697 YP_003805255.1 CDS Spirs_3573 NC_014364.1 3845453 3847651 R COGs: COG0815 Apolipoprotein N-acyltransferase; InterPro IPR004563:IPR003010; KEGG: tde:TDE1708 apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: Apolipoprotein N-acyltransferase 1; TIGRFAM: apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; TIGRFAM: apolipoprotein N-acyltransferase; apolipoprotein N-acyltransferase complement(3845453..3847651) Spirochaeta smaragdinae DSM 11293 9491698 YP_003805256.1 CDS Spirs_3574 NC_014364.1 3847705 3848307 R COGs: COG0637 phosphatase/phosphohexomutase; InterPro IPR005834:IPR005833:IPR006402; KEGG: bba:Bd2810 phosphatase; PFAM: haloacid dehalogenase; SPTR: phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; HAD-superfamily hydrolase complement(3847705..3848307) Spirochaeta smaragdinae DSM 11293 9491699 YP_003805257.1 CDS Spirs_3575 NC_014364.1 3848319 3848678 R COGs: COG0662 mannose-6-phosphate isomerase; InterPro IPR013096; KEGG: bcz:BCZK2699 hypothetical protein; PFAM: Cupin 2 conserved barrel domain protein; SPTR: polyketide synthesis domain protein; PFAM: Cupin domain; cupin complement(3848319..3848678) Spirochaeta smaragdinae DSM 11293 9491700 YP_003805258.1 CDS Spirs_3576 NC_014364.1 3848708 3850264 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485; KEGG: bcb:BCB4264_A2981 autoinducer-2 (AI-2) kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: uncharacterized protein; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(3848708..3850264) Spirochaeta smaragdinae DSM 11293 9491701 YP_003805259.1 CDS Spirs_3577 NC_014364.1 3850322 3851362 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: monosacharide ABC transporter periplasmic monosacharide-binding protein; SPTR: uncharacterized protein; sugar ABC transporter periplasmic protein complement(3850322..3851362) Spirochaeta smaragdinae DSM 11293 9491702 YP_003805260.1 CDS Spirs_3578 NC_014364.1 3851442 3852449 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: bcb:BCB4264_A2977 ribose ABC transporter permease; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; sugar ABC transporter permease complement(3851442..3852449) Spirochaeta smaragdinae DSM 11293 9491703 YP_003805261.1 CDS Spirs_3579 NC_014364.1 3852446 3853450 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: monosacharide ABC transporter permease; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator complement(3852446..3853450) Spirochaeta smaragdinae DSM 11293 9491704 YP_003805262.1 CDS Spirs_3580 NC_014364.1 3853443 3854951 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: monosacharide ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(3853443..3854951) Spirochaeta smaragdinae DSM 11293 9491705 YP_003805263.1 CDS Spirs_3581 NC_014364.1 3854969 3855835 R COGs: COG1830 DhnA-type fructose-1 6-bisphosphate aldolase; InterPro IPR002915:IPR018294; KEGG: bcz:BCZK2700 aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; SPTR: Possible fructose-bisphosphate aldolase; PFAM: DeoC/LacD family aldolase; deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase complement(3854969..3855835) Spirochaeta smaragdinae DSM 11293 9491706 YP_003805264.1 CDS Spirs_3582 NC_014364.1 3856049 3857032 D COGs: COG2390 transcriptional regulator contains sigma factor-related N-terminal domain; InterPro IPR007324; KEGG: ttr:Tter_2050 DeoR family transcriptional regulator; PFAM: sugar-binding domain protein; SPTR: DeoR family transcriptional regulator; PFAM: sugar-binding domain; DeoR family transcriptional regulator 3856049..3857032 Spirochaeta smaragdinae DSM 11293 9491707 YP_003805265.1 CDS Spirs_3583 NC_014364.1 3857032 3857982 D InterPro IPR004776; KEGG: pmo:Pmob_1605 hypothetical protein; PFAM: hypothetical protein; SPTR: hypothetical protein; hypothetical protein 3857032..3857982 Spirochaeta smaragdinae DSM 11293 9491708 YP_003805266.1 CDS Spirs_3584 NC_014364.1 3858208 3858978 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: azl:AZL_b01550 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier-protein] reductase; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 3858208..3858978 Spirochaeta smaragdinae DSM 11293 9491709 YP_003805267.1 CDS Spirs_3585 NC_014364.1 3859075 3860133 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sus:acid_2122 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; TIGRFAM: bacteriochlorophyll 4-vinyl reductase; PfkB domain-containing protein complement(3859075..3860133) Spirochaeta smaragdinae DSM 11293 9491710 YP_003805268.1 CDS Spirs_3586 NC_014364.1 3860126 3860758 R COGs: COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase; InterPro IPR000887; KEGG: aco:Amico_1665 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; SPTR: uncharacterized protein; TIGRFAM: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; PFAM: KDPG and KHG aldolase; TIGRFAM: Entner-Doudoroff aldolase; 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase complement(3860126..3860758) Spirochaeta smaragdinae DSM 11293 9491711 YP_003805269.1 CDS Spirs_3587 NC_014364.1 3860910 3861758 D COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: bpu:BPUM_3680 hypothetical protein; PFAM: protein of unknown function DUF62; SPTR: uncharacterized protein; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase; hypothetical protein 3860910..3861758 Spirochaeta smaragdinae DSM 11293 9491712 YP_003805270.1 CDS Spirs_3588 NC_014364.1 3861788 3862633 D COGs: COG1912 conserved hypothetical protein; InterPro IPR002747; KEGG: aha:AHA_0746 hypothetical protein; PFAM: protein of unknown function DUF62; SPTR: Molybdate/tungstate binding protein; PFAM: S-adenosyl-l-methionine hydroxide adenosyltransferase; hypothetical protein 3861788..3862633 Spirochaeta smaragdinae DSM 11293 9491713 YP_003805271.1 CDS Spirs_3589 NC_014364.1 3862651 3863205 D COGs: COG4720 membrane protein; InterPro IPR009825; KEGG: vsa:VSAL_I1988 hypothetical protein; PFAM: protein of unknown function DUF1393; SPTR: UPF0397 protein VSAL_I1988; PFAM: protein of unknown function (DUF1393); hypothetical protein 3862651..3863205 Spirochaeta smaragdinae DSM 11293 9491714 YP_003805272.1 CDS Spirs_3590 NC_014364.1 3863202 3864944 D COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR003593:IPR003439:IPR017871; KEGG: vex:VEA_001242 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Cobalt import ATP-binding protein CbiO; PFAM: ABC transporter; ATP-binding cassette cobalt transporter; ABC transporter 3863202..3864944 Spirochaeta smaragdinae DSM 11293 9491715 YP_003805273.1 CDS Spirs_3591 NC_014364.1 3864905 3865744 D COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: vpa:VPA1483 ABC transporter membrane-spanning permease; PFAM: cobalt transport protein; SPTR: transmembrane component MtsC of energizing module of methionine-regulated ECF transporter; PFAM: Cobalt transporter; cobalt transporter 3864905..3865744 Spirochaeta smaragdinae DSM 11293 9491716 YP_003805274.1 CDS Spirs_3592 NC_014364.1 3866167 3867087 D COGs: COG1131 ABC-type multidrug transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871:IPR005894; KEGG: amt:Amet_0234 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter; TIGRFAM: daunorubicin resistance ABC transporter ATP-binding subunit; daunorubicin resistance ABC transporter ATPase 3866167..3867087 Spirochaeta smaragdinae DSM 11293 9491717 YP_003805275.1 CDS Spirs_3593 NC_014364.1 3867087 3867914 D InterPro IPR013525:IPR013526:IPR000412; KEGG: ckr:CKR_2155 hypothetical protein; PFAM: ABC transporter; SPTR: ABC-2 type transporter; PFAM: ABC transporter; ABC transporter 3867087..3867914 Spirochaeta smaragdinae DSM 11293 9491718 YP_003805276.1 CDS Spirs_3594 NC_014364.1 3867945 3868505 D InterPro IPR000835; KEGG: dae:Dtox_1920 transcriptional regulator, MarR family; PFAM: regulatory protein MarR; SMART: regulatory protein MarR; SPTR: MarR family transcriptional regulator; PFAM: MarR family; MarR family transcriptional regulator 3867945..3868505 Spirochaeta smaragdinae DSM 11293 9491719 YP_003805277.1 CDS Spirs_3595 NC_014364.1 3868570 3870033 R COGs: COG0362 6-phosphogluconate dehydrogenase; InterProIPR006115:IPR006114:IPR006184:IPR006183:IPR 006113; KEGG: cja:CJA_3099 6-phosphogluconate dehydrogenase; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase NAD-binding; SPTR: 6-phosphogluconate dehydrogenase, decarboxylating; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, C-terminal domain; TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase complement(3868570..3870033) Spirochaeta smaragdinae DSM 11293 9491720 YP_003805278.1 CDS Spirs_3596 NC_014364.1 3870036 3871310 R COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: aba:acid345_4308 hypothetical protein; PFAM: protein of unknown function DUF2088; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2088); hypothetical protein complement(3870036..3871310) Spirochaeta smaragdinae DSM 11293 9491721 YP_003805279.1 CDS Spirs_3597 NC_014364.1 3871312 3872127 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: rfr:Rfer_0952 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3871312..3872127) Spirochaeta smaragdinae DSM 11293 9491722 YP_003805280.1 CDS Spirs_3598 NC_014364.1 3872138 3873016 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: rfr:Rfer_0953 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3872138..3873016) Spirochaeta smaragdinae DSM 11293 9491723 YP_003805281.1 CDS Spirs_3599 NC_014364.1 3873104 3874381 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: rfr:Rfer_0954 extracellular solute-binding protein; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein, family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3873104..3874381) Spirochaeta smaragdinae DSM 11293 9491724 YP_003805282.1 CDS Spirs_3600 NC_014364.1 3874536 3875378 D COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: transcriptional regulator (RpiR family) protein; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator 3874536..3875378 Spirochaeta smaragdinae DSM 11293 9491725 YP_003805283.1 CDS Spirs_3601 NC_014364.1 3875426 3876502 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: sus:acid_7084 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 3875426..3876502 Spirochaeta smaragdinae DSM 11293 9491726 YP_003805284.1 CDS Spirs_3602 NC_014364.1 3876519 3877553 D COGs: COG1063 threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013154:IPR013149:IPR002328; KEGG: sus:acid_7535 alcohol dehydrogenase; PFAM: alcohol dehydrogenase GroES domain protein; alcohol dehydrogenase zinc-binding domain protein; SPTR: alcohol dehydrogenase GroES domain protein; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase GroES domain-containing protein 3876519..3877553 Spirochaeta smaragdinae DSM 11293 9491727 YP_003805285.1 CDS Spirs_3603 NC_014364.1 3877550 3878617 D COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sli:Slin_4507 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase domain protein; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein 3877550..3878617 Spirochaeta smaragdinae DSM 11293 9491728 YP_003805286.1 CDS Spirs_3604 NC_014364.1 3878648 3880066 R COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR003953:IPR010960; KEGG: ctc:CTC01522 fumarate reductase flavoprotein; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; PRIAM: succinate dehydrogenase; SPTR: fumarate reductase flavoprotein; TIGRFAM: flavocytochrome C; PFAM: FAD binding domain; TIGRFAM: flavocytochrome C; flavocytochrome C complement(3878648..3880066) Spirochaeta smaragdinae DSM 11293 9491729 YP_003805287.1 CDS Spirs_3605 NC_014364.1 3880063 3880782 R COGs: COG4565 Response regulator of citrate/malate metabolism; InterPro IPR001789; KEGG: cbe:Cbei_4004 response regulator receiver; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator; PFAM: HTH domain; Response regulator receiver domain; response regulator receiver and unknown domain-containing protein complement(3880063..3880782) Spirochaeta smaragdinae DSM 11293 9491730 YP_003805288.1 CDS Spirs_3606 NC_014364.1 3880779 3882362 R COGs: COG3290 Signal transduction histidine kinase regulating citrate/malate metabolism; InterPro IPR003594:IPR013767:IPR004358:IPR005467; KEGG: cbe:Cbei_4005 signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: ATP-binding region ATPase domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase regulating citrate/malate metabolism; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase regulating citrate/malate metabolism complement(3880779..3882362) Spirochaeta smaragdinae DSM 11293 9491731 YP_003805289.1 CDS Spirs_3607 NC_014364.1 3882452 3884188 R COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR007329:IPR003953:IPR002202:IPR010960; KEGG: aoe:Clos_0390 flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; PRIAM: succinate dehydrogenase; SPTR: succinate dehydrogenase; TIGRFAM: flavocytochrome C; PFAM: FAD binding domain; FMN-binding domain; TIGRFAM: flavocytochrome C; flavocytochrome C complement(3882452..3884188) Spirochaeta smaragdinae DSM 11293 9491732 YP_003805290.1 CDS Spirs_3608 NC_014364.1 3884328 3884630 R InterPro IPR003477; KEGG: npu:Npun_R1595 MazF family transcriptional regulator; PFAM: PemK family protein; SPTR: MazF family transcriptional regulator; manually curated; PFAM: PemK-like protein; MazF family transcriptional regulator complement(3884328..3884630) Spirochaeta smaragdinae DSM 11293 9491733 YP_003805291.1 CDS Spirs_3609 NC_014364.1 3884614 3885798 R COGs: COG2856 Zn peptidase; InterPro IPR001387:IPR010359; KEGG: adg:Adeg_0686 helix-turn-helix domain protein; PFAM: protein of unknown function DUF955; helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: Helix-turn-helix domain protein; PFAM: Helix-turn-helix; Domain of unknown function (DUF955); hypothetical protein complement(3884614..3885798) Spirochaeta smaragdinae DSM 11293 9491734 YP_003805292.1 CDS Spirs_3610 NC_014364.1 3886023 3887156 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: aoe:Clos_0218 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 3886023..3887156 Spirochaeta smaragdinae DSM 11293 9491735 YP_003805293.1 CDS Spirs_3611 NC_014364.1 3887170 3888378 D COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR001453:IPR020817; KEGG: aoe:Clos_0219 molybdenum cofactor synthesis domain-containing protein; PFAM: molybdopterin binding domain; MoeA domain protein domain I and II; SPTR: Molybdenum cofactor synthesis domain protein; TIGRFAM: molybdenum cofactor synthesis protein; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor synthesis protein 3887170..3888378 Spirochaeta smaragdinae DSM 11293 9491736 YP_003805294.1 CDS Spirs_3612 NC_014364.1 3888365 3889393 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: ckr:CKR_1584 hypothetical protein; PFAM: transporter permease; SPTR: transporter permease; PFAM: FecCD transport family; transporter permease 3888365..3889393 Spirochaeta smaragdinae DSM 11293 9491737 YP_003805295.1 CDS Spirs_3613 NC_014364.1 3889390 3890172 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR003593:IPR003439:IPR017871; KEGG: ckr:CKR_1585 hypothetical protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 3889390..3890172 Spirochaeta smaragdinae DSM 11293 9491738 YP_003805296.1 CDS Spirs_3615 NC_014364.1 3890734 3891693 D COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: cac:CAC1453 ribose ABC transporter periplasmic ribose-binding protein; SPTR: uncharacterized protein; PFAM: family; sugar ABC transporter periplasmic protein 3890734..3891693 Spirochaeta smaragdinae DSM 11293 9491740 YP_003805297.1 CDS Spirs_3616 NC_014364.1 3891782 3893290 D COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: str:Sterm_3540 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: uncharacterized protein; PFAM: ABC transporter; sugar ABC transporter ATPase 3891782..3893290 Spirochaeta smaragdinae DSM 11293 9491741 YP_003805298.1 CDS Spirs_3617 NC_014364.1 3893283 3894302 D COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: lhk:LHK_01713 RbsC; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease; inner-membrane translocator 3893283..3894302 Spirochaeta smaragdinae DSM 11293 9491742 YP_003805299.1 CDS Spirs_3618 NC_014364.1 3894318 3895793 D COGs: COG1621 beta-fructosidase (levanase/invertase); InterPro IPR001362:IPR013148; KEGG: fgr:FG02067.1 hypothetical protein; PFAM: glycosyl hydrolase family 32; SMART: glycoside hydrolase family 32; SPTR: uncharacterized protein; PFAM: glycosyl hydrolases family 32 N-terminal domain; glycoside hydrolase family protein 3894318..3895793 Spirochaeta smaragdinae DSM 11293 9491743 YP_003805300.1 CDS Spirs_3619 NC_014364.1 3895889 3897916 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: two-component sensor histidine kinase/response regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: Monosaccharide ABC transporter substrate-binding protein, CUT2 family (TC 3.A.1.2.-); PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3895889..3897916) Spirochaeta smaragdinae DSM 11293 9491744 YP_003805301.1 CDS Spirs_3621 NC_014364.1 3898992 3900197 R COGs: COG2942 N-acyl-D-glucosamine 2-epimerase; InterPro IPR010819; KEGG: phe:Phep_3251 N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase; PRIAM: N-acylglucosamine 2-epimerase; SPTR: N-acylglucosamine 2-epimerase; PFAM: N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase); N-acylglucosamine 2-epimerase complement(3898992..3900197) Spirochaeta smaragdinae DSM 11293 9491746 YP_003805302.1 CDS Spirs_3622 NC_014364.1 3900216 3901376 R COGs: COG4214 ABC-type xylose transporter permease component; InterPro IPR001851; KEGG: hor:Hore_19480 monosaccharide-transporting ATPase; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(3900216..3901376) Spirochaeta smaragdinae DSM 11293 9491747 YP_003805303.1 CDS Spirs_3623 NC_014364.1 3901389 3902912 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003593:IPR003439:IPR017871; KEGG: amt:Amet_2813 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(3901389..3902912) Spirochaeta smaragdinae DSM 11293 9491748 YP_003805304.1 CDS Spirs_3624 NC_014364.1 3902993 3904057 R COGs: COG4213 ABC-type xylose transporter periplasmic component; KEGG: afl:Aflv_1310 ABC-type ribose transporter, periplasmic component; SPTR: ABC-type ribose transporter, periplasmic component; PFAM: family; TIGRFAM: D-xylose ABC transporter substrate-binding protein; ABC-type ribose transporter, periplasmic component complement(3902993..3904057) Spirochaeta smaragdinae DSM 11293 9491749 YP_003805305.1 CDS Spirs_3625 NC_014364.1 3904097 3905041 R InterPro IPR010181; KEGG: aco:Amico_1256 C_GCAxxG_C_C family protein; PFAM: C_GCAxxG_C_C family protein; SPTR: C_GCAxxG_C_C family protein; PFAM: redox-active protein (C_GCAxxG_C_C); C_GCAxxG_C_C family protein complement(3904097..3905041) Spirochaeta smaragdinae DSM 11293 9491750 YP_003805306.1 CDS Spirs_3626 NC_014364.1 3905061 3905759 R COGs: COG0274 deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: rrs:RoseRS_1083 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: deoxyribose-phosphate aldolase; SPTR: deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase complement(3905061..3905759) Spirochaeta smaragdinae DSM 11293 9491751 YP_003805307.1 CDS Spirs_3627 NC_014364.1 3905852 3906865 R COGs: COG1609 transcriptional regulators; InterPro IPR000524; KEGG: tex:Teth514_0985 periplasmic binding protein/LacI transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: Periplasmic binding protein/LacI transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; regulatory protein GntR complement(3905852..3906865) Spirochaeta smaragdinae DSM 11293 9491752 YP_003805308.1 CDS Spirs_3628 NC_014364.1 3906866 3907516 R COGs: COG0176 transaldolase; InterPro IPR018225; KEGG: mes:Meso_3212 translaldolase; SPTR: Probable transaldolase; PFAM: transaldolase; transaldolase complement(3906866..3907516) Spirochaeta smaragdinae DSM 11293 9491753 YP_003805309.1 CDS Spirs_3629 NC_014364.1 3907537 3908295 R COGs: COG4821 Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain; KEGG: rca:Rcas_2756 hypothetical protein; SPTR: Uncharacterized protein containing SIS (Sugar isomerase) phosphosugar binding domain-like protein; hypothetical protein complement(3907537..3908295) Spirochaeta smaragdinae DSM 11293 9491754 YP_003805310.1 CDS Spirs_3630 NC_014364.1 3908394 3909344 D COGs: COG1940 transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: sli:Slin_2646 ROK family protein; PFAM: ROK family protein; SPTR: ROK family protein; PFAM: ROK family; ROK family protein 3908394..3909344 Spirochaeta smaragdinae DSM 11293 9491755 YP_003805311.1 CDS Spirs_3631 NC_014364.1 3909372 3912512 R COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterProIPR014001:IPR001650:IPR007527:IPR000330:IPR 014021; KEGG: drt:Dret_0283 SNF2-related protein; PFAM: SNF2-related protein; zinc finger SWIM domain protein; helicase; SMART: DEAD-like helicase ; helicase; SPTR: SNF2-related protein; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; SWIM zinc finger; SNF2-like protein complement(3909372..3912512) Spirochaeta smaragdinae DSM 11293 9491756 YP_003805312.1 CDS Spirs_3632 NC_014364.1 3912618 3913607 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: tpd:Teth39_0633 LacI family transcription regulator; PFAM: regulatory protein LacI; periplasmic binding protein/LacI transcriptional regulator; SMART: regulatory protein LacI; SPTR: LacI family transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(3912618..3913607) Spirochaeta smaragdinae DSM 11293 9491757 YP_003805313.1 CDS Spirs_3633 NC_014364.1 3913608 3914480 R COGs: COG1235 metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: efa:EF1816 hypothetical protein; SPTR: Predicted protein; hypothetical protein complement(3913608..3914480) Spirochaeta smaragdinae DSM 11293 9491758 YP_003805314.1 CDS Spirs_3634 NC_014364.1 3914483 3915334 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hau:Haur_1152 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3914483..3915334) Spirochaeta smaragdinae DSM 11293 9491759 YP_003805315.1 CDS Spirs_3635 NC_014364.1 3915339 3916286 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hau:Haur_1151 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3915339..3916286) Spirochaeta smaragdinae DSM 11293 9491760 YP_003805316.1 CDS Spirs_3636 NC_014364.1 3916325 3917605 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: hor:Hore_15560 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3916325..3917605) Spirochaeta smaragdinae DSM 11293 9491761 YP_003805317.1 CDS Spirs_3637 NC_014364.1 3917909 3918700 D InterPro IPR004843:IPR010916:IPR011152; KEGG: rrs:RoseRS_4037 metallophosphoesterase; PFAM: metallophosphoesterase; SPTR: metallophosphoesterase; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family; metallophosphoesterase 3917909..3918700 Spirochaeta smaragdinae DSM 11293 9491762 YP_003805318.1 CDS Spirs_3638 NC_014364.1 3918697 3919386 D COGs: COG2365 protein tyrosine/serine phosphatase; KEGG: apr:Apre_0673 protein tyrosine/serine phosphatase; SPTR: protein tyrosine/serine phosphatase; protein tyrosine/serine phosphatase 3918697..3919386 Spirochaeta smaragdinae DSM 11293 9491763 YP_003805319.1 CDS Spirs_3639 NC_014364.1 3919666 3922644 R COGs: COG1554 Trehalose and maltose hydrolase ( phosphorylase); InterProIPR005196:IPR005195:IPR005194:IPR005834:IPR 010972:IPR010976:IPR006402; KEGG: mdi:METDI0534 glycoside hydrolase or sugar phosphorilase; PFAM: glycoside hydrolase family 65 central catalytic; glycoside hydrolase family 65 domain protein; Haloacid dehalogenase domain protein hydrolase; SPTR: Trehalose phosphorylase; TIGRFAM: beta-phosphoglucomutase; beta-phosphoglucomutase family hydrolase; HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: glycosyl hydrolase family 65, C-terminal domain; glycosyl hydrolase family 65, N-terminal domain; glycosyl hydrolase family 65 central catalytic domain; haloacid dehalogenase-like hydrolase; TIGRFAM: beta-phosphoglucomutase family hydrolase; beta-phosphoglucomutase; haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; beta-phosphoglucomutase complement(3919666..3922644) Spirochaeta smaragdinae DSM 11293 9491764 YP_003805320.1 CDS Spirs_3640 NC_014364.1 3922762 3924282 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR000014:IPR003594:IPR011495:IPR005467; KEGG: rci:RCIX420 signal transduction histidine kinase, fragment 2; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: Predicted signal transduction histidine kinase, 2; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 3922762..3924282 Spirochaeta smaragdinae DSM 11293 9491765 YP_003805321.1 CDS Spirs_3641 NC_014364.1 3924342 3925103 D KEGG: htu:Htur_1349 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 3924342..3925103 Spirochaeta smaragdinae DSM 11293 9491766 YP_003805322.1 CDS Spirs_3642 NC_014364.1 3925198 3926847 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484; KEGG: bhy:BHWA1_00789 xylulose kinase; PFAM: carbohydrate kinase, FGGY-like; PRIAM: xylulokinase; SPTR: Xylulose kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; xylulokinase complement(3925198..3926847) Spirochaeta smaragdinae DSM 11293 9491767 YP_003805323.1 CDS Spirs_3643 NC_014364.1 3926934 3928217 R COGs: COG2233 xanthine/uracil permease; InterPro IPR006043:IPR000627:IPR006042; KEGG: afw:Anae109_0056 uracil-xanthine permease; PFAM: xanthine/uracil/vitamin C permease; SPTR: uracil-xanthine permease; TIGRFAM: uracil-xanthine permease; PFAM: Permease family; TIGRFAM: uracil-xanthine permease; uracil-xanthine permease complement(3926934..3928217) Spirochaeta smaragdinae DSM 11293 9491768 YP_003805324.1 CDS Spirs_3644 NC_014364.1 3928405 3929379 R COGs: COG1052 lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: dal:Dalk_2294 glyoxylate reductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: glyoxylate reductase; manually curated; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase complement(3928405..3929379) Spirochaeta smaragdinae DSM 11293 9491769 YP_003805325.1 CDS Spirs_3645 NC_014364.1 3929596 3930183 D COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR003781; KEGG: dth:DICTH_0414 redox-sensing transcriptional repressor REX; PFAM: CoA-binding protein; SPTR: Redox-sensing transcriptional repressor rex 2; PFAM: CoA binding domain; DNA-binding protein N-terminus; CoA-binding protein 3929596..3930183 Spirochaeta smaragdinae DSM 11293 9491770 YP_003805326.1 CDS Spirs_3646 NC_014364.1 3930380 3931042 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: gem:GM21_3105 two component transcriptional regulator, LuxR family; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(3930380..3931042) Spirochaeta smaragdinae DSM 11293 9491771 YP_003805327.1 CDS Spirs_3647 NC_014364.1 3931121 3931987 D COGs: COG0483 fructose-1 6-bisphosphatase of inositol monophosphatase family; InterPro IPR000760:IPR020583:IPR020550; KEGG: gsu:GSU0942 inositol-1-monophosphatase; PFAM: inositol monophosphatase; SPTR: inositol-1-monophosphatase; PFAM: inositol monophosphatase family; inositol monophosphatase 3931121..3931987 Spirochaeta smaragdinae DSM 11293 9491772 YP_003805328.1 CDS Spirs_3648 NC_014364.1 3932105 3932977 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: hor:Hore_20850 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3932105..3932977) Spirochaeta smaragdinae DSM 11293 9491773 YP_003805329.1 CDS Spirs_3649 NC_014364.1 3932967 3934040 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hor:Hore_20860 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3932967..3934040) Spirochaeta smaragdinae DSM 11293 9491774 YP_003805330.1 CDS Spirs_3650 NC_014364.1 3934117 3935454 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: hor:Hore_20870 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(3934117..3935454) Spirochaeta smaragdinae DSM 11293 9491775 YP_003805331.1 CDS Spirs_3651 NC_014364.1 3935649 3936119 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 3935649..3936119 Spirochaeta smaragdinae DSM 11293 9491776 YP_003805332.1 CDS Spirs_3652 NC_014364.1 3936082 3936969 R COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: dsy:DSY0819 hypothetical protein; PFAM: Integrase catalytic region; SPTR: uncharacterized protein; PFAM: Integrase core domain; Integrase catalytic subunit complement(3936082..3936969) Spirochaeta smaragdinae DSM 11293 9491777 YP_003805333.1 CDS Spirs_3653 NC_014364.1 3936981 3937256 R InterPro IPR002514; KEGG: dsy:DSY0820 hypothetical protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase; PFAM: transposase; transposase IS3/IS911 family protein complement(3936981..3937256) Spirochaeta smaragdinae DSM 11293 9491778 YP_003805334.1 CDS Spirs_3654 NC_014364.1 3937280 3938050 D KEGG: hor:Hore_06690 methyl-accepting chemotaxis sensory transducer; SPTR: Myosin-like protein; hypothetical protein 3937280..3938050 Spirochaeta smaragdinae DSM 11293 9491779 YP_003805335.1 CDS Spirs_3655 NC_014364.1 3938041 3938472 D KEGG: tai:Taci_0690 hypothetical protein; SPTR: uncharacterized protein; PFAM: DRTGG domain; hypothetical protein 3938041..3938472 Spirochaeta smaragdinae DSM 11293 9491780 YP_003805336.1 CDS Spirs_3656 NC_014364.1 3938492 3938908 D COGs: COG2172 anti-sigma regulatory factor (Ser/Thr protein kinase); InterPro IPR003594; KEGG: pdi:BDI_1096 anti-sigma regulatory factor; PFAM: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; anti-sigma regulatory factor, serine/threonine protein kinase 3938492..3938908 Spirochaeta smaragdinae DSM 11293 9491781 YP_003805337.1 CDS Spirs_3657 NC_014364.1 3938915 3940258 D COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR001450:IPR007202:IPR017900:IPR017896; KEGG: pdi:BDI_1095 ferredoxin 2; PFAM: Fe-S cluster domain protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SPTR: uncharacterized protein; PFAM: Iron only hydrogenase large subunit, C-terminal domain; Fe-S cluster; 4Fe-4S binding domain; Fe-S cluster domain-containing protein 3938915..3940258 Spirochaeta smaragdinae DSM 11293 9491782 YP_003805338.1 CDS Spirs_3658 NC_014364.1 3940502 3941251 D COGs: COG0588 phosphoglycerate mutase 1; InterPro IPR005952:IPR013078:IPR001345; KEGG: tte:TTE2487 phosphoglycerate mutase 1; PFAM: phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; TIGRFAM: phosphoglycerate mutase 1 family; PFAM: phosphoglycerate mutase family; TIGRFAM: phosphoglycerate mutase, BPG-dependent, family 1; phosphoglycerate mutase 1 family 3940502..3941251 Spirochaeta smaragdinae DSM 11293 9491783 YP_003805339.1 CDS Spirs_3659 NC_014364.1 3941266 3942621 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cby:CLM_3203 MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(3941266..3942621) Spirochaeta smaragdinae DSM 11293 9491784 YP_003805340.1 CDS Spirs_3660 NC_014364.1 3942618 3945587 R COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR007863:IPR013578; KEGG: sat:SYN_00812 insulinase family metalloprotease; PFAM: peptidase M16C associated domain protein; peptidase M16 domain protein; SPTR: metalloprotease insulinase family; PFAM: peptidase M16C associated; peptidase M16 inactive domain; peptidase M16C associated domain-containing protein complement(3942618..3945587) Spirochaeta smaragdinae DSM 11293 9491785 YP_003805341.1 CDS Spirs_3661 NC_014364.1 3945606 3947804 R COGs: COG2183 transcriptional accessory protein; InterPro IPR006641:IPR018974:IPR003029; KEGG: sfu:Sfum_1838 RNA-binding S1 domain-containing protein; PFAM: Tex-like protein-like; RNA binding S1 domain protein; SMART: Resolvase RNase H domain protein fold; SPTR: RNA binding S1 domain protein; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; Tex-like protein complement(3945606..3947804) Spirochaeta smaragdinae DSM 11293 9491786 YP_003805342.1 CDS Spirs_3662 NC_014364.1 3947970 3949253 R COGs: COG1457 Purine-cytosine permease and related protein; InterPro IPR001248; KEGG: bld:BLi01981 hypothetical protein; PFAM: permease for cytosine/purines uracil thiamine allantoin; SPTR: Permease for cytosine/purine, uracil, thiamine, allantoin; PFAM: Permease for cytosine/purines, uracil, thiamine, allantoin; TIGRFAM: NCS1 nucleoside transporter family; cytosine/purines uracil thiamine allantoin permease complement(3947970..3949253) Spirochaeta smaragdinae DSM 11293 9491787 YP_003805343.1 CDS Spirs_3663 NC_014364.1 3949268 3950398 R COGs: COG3535 conserved hypothetical protein; InterPro IPR010318; KEGG: dhd:Dhaf_2201 protein of unknown function DUF917; PFAM: protein of unknown function DUF917; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF917); hypothetical protein complement(3949268..3950398) Spirochaeta smaragdinae DSM 11293 9491788 YP_003805344.1 CDS Spirs_3664 NC_014364.1 3950422 3951189 R COGs: COG1414 transcriptional regulator; InterPro IPR005471:IPR014757; KEGG: tle:Tlet_1864 transcriptional regulator, TrmB; PFAM: transcriptional regulator IclR ; regulatory protein IclR; SMART: regulatory protein IclR; SPTR: transcriptional regulator, TrmB; PFAM: IclR helix-turn-helix domain; Bacterial transcriptional regulator; IclR family transcriptional regulator complement(3950422..3951189) Spirochaeta smaragdinae DSM 11293 9491789 YP_003805345.1 CDS Spirs_3665 NC_014364.1 3951323 3952297 D COGs: COG2269 Truncated possibly inactive lysyl-tRNA synthetase (class II); InterPro IPR004364:IPR018149:IPR006195; KEGG: tpp:TPASS_1040 lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); SPTR: tRNA synthetase, class II family; PFAM: tRNA synthetases class II (D, K and N); TIGRFAM: lysyl-tRNA synthetase-related protein GenX; tRNA synthetase class II (D K and N) 3951323..3952297 Spirochaeta smaragdinae DSM 11293 9491790 YP_003805346.1 CDS Spirs_3666 NC_014364.1 3952359 3952922 D COGs: COG0231 translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterProIPR011768:IPR013185:IPR001059:IPR015365:IPR 013852:IPR020599; KEGG: tde:TDE0968 translation elongation factor P; PFAM: Elongation factor P ; Elongation factor KOW domain protein; Elongation factor P/YeiP protein; SPTR: Elongation factor P; TIGRFAM: translation elongation factor P; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P; translation elongation factor P 3952359..3952922 Spirochaeta smaragdinae DSM 11293 9491791 YP_003805347.1 CDS Spirs_3667 NC_014364.1 3952900 3954153 D COGs: COG2813 16S RNA G1207 methylase RsmC; InterPro IPR007848; KEGG: rrs:RoseRS_3753 methyltransferase small; PFAM: methyltransferase small; SPTR: methyltransferase small; PFAM: methyltransferase small domain; methyltransferase small 3952900..3954153 Spirochaeta smaragdinae DSM 11293 9491792 YP_003805348.1 CDS Spirs_3668 NC_014364.1 3954201 3954617 D COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: nhl:Nhal_1929 iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; SPTR: Predicted transcriptional regulator, YjeB/RRF2 family protein; TIGRFAM: transcriptional regulator, Rrf2 family; PFAM: transcriptional regulator; TIGRFAM: rrf2 family protein ( transcriptional regulator); BadM/Rrf2 family transcriptional regulator 3954201..3954617 Spirochaeta smaragdinae DSM 11293 9491793 YP_003805349.1 CDS Spirs_3669 NC_014364.1 3954574 3955770 R COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: pvi:Cvib_0174 MscS mechanosensitive ion channel; PFAM: MscS Mechanosensitive ion channel; SPTR: MscS Mechanosensitive ion channel; PFAM: Mechanosensitive ion channel; mechanosensitive ion channel MscS complement(3954574..3955770) Spirochaeta smaragdinae DSM 11293 9491794 YP_003805350.1 CDS Spirs_3670 NC_014364.1 3955721 3957526 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterProIPR000014:IPR003607:IPR013767:IPR013656:IPR 006674:IPR000700; KEGG: dol:Dole_1678 PAS/PAC sensor protein; PFAM: metal-dependent phosphohydrolase HD sub domain; hypothetical protein; PAS fold domain protein; SMART: metal-dependent phosphohydrolase HD region; PAS domain containing protein; SPTR: PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; PFAM: HD domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor protein complement(3955721..3957526) Spirochaeta smaragdinae DSM 11293 9491795 YP_003805351.1 CDS Spirs_3671 NC_014364.1 3957638 3958669 D COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: OmpA/MotB domain-containing protein; PFAM: OmpA/MotB domain protein; SPTR: OmpA family protein; PFAM: OmpA family; OmpA/MotB domain-containing protein 3957638..3958669 Spirochaeta smaragdinae DSM 11293 9491796 YP_003805352.1 CDS Spirs_3672 NC_014364.1 3958677 3959801 R COGs: COG1509 lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: min:Minf_0017 lysine 2,3-aminomutase; PFAM: radical SAM domain protein; PRIAM: lysine 2,3-aminomutase; SPTR: lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; manually curated; PFAM: radical SAM superfamily; TIGRFAM: KamA family protein; lysine 2,3-aminomutase YodO family protein complement(3958677..3959801) Spirochaeta smaragdinae DSM 11293 9491797 YP_003805353.1 CDS Spirs_3673 NC_014364.1 3959882 3961195 D COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR011701; KEGG: tde:TDE0798 transporter PFAM: major facilitator superfamily MFS_1; SPTR: transporter ; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 3959882..3961195 Spirochaeta smaragdinae DSM 11293 9491798 YP_003805354.1 CDS Spirs_3674 NC_014364.1 3961267 3961983 R InterPro IPR007730; KEGG: tde:TDE1639 sporulation repeat-containing protein; PFAM: sporulation domain protein; SPTR: sporulation related repeat protein; PFAM: sporulation related domain; sporulation domain-containing protein complement(3961267..3961983) Spirochaeta smaragdinae DSM 11293 9491799 YP_003805355.1 CDS Spirs_3675 NC_014364.1 3962001 3962588 R COGs: COG0237 Dephospho-CoA kinase; InterPro IPR001977; KEGG: acp:A2cp1_2870 dephospho-CoA kinase; SPTR: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; TIGRFAM: dephospho-CoA kinase; dephospho-CoA kinase complement(3962001..3962588) Spirochaeta smaragdinae DSM 11293 9491800 YP_003805356.1 CDS Spirs_3676 NC_014364.1 3962588 3965323 R COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR019825:IPR019760:IPR002421:IPR008918:IPR 002562:IPR001098:IPR020046:IPR020047:IPR018320:IPR002298; KEGG: tde:TDE1637 DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease, N-terminal resolvase-like domain; 5'-3' exonuclease, SAM-fold domain; 3'-5' exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: 5'-3' exonuclease; Helix-hairpin-helix domain protein class 2; 3'-5' exonuclease; DNA-directed DNA polymerase; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: 3'-5' exonuclease; 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I; DNA polymerase I complement(3962588..3965323) Spirochaeta smaragdinae DSM 11293 9491801 YP_003805357.1 CDS Spirs_3677 NC_014364.1 3965320 3965772 R KEGG: tde:TDE0118 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3965320..3965772) Spirochaeta smaragdinae DSM 11293 9491802 YP_003805358.1 CDS Spirs_3678 NC_014364.1 3965801 3966229 R COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: tde:TDE0119 flagellar protein FliS; PFAM: flagellar protein FliS; SPTR: flagellar protein FliS; TIGRFAM: flagellar protein FliS; PFAM: flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS; flagellar protein FliS complement(3965801..3966229) Spirochaeta smaragdinae DSM 11293 9491803 YP_003805359.1 CDS Spirs_3679 NC_014364.1 3966226 3966354 R hypothetical protein complement(3966226..3966354) Spirochaeta smaragdinae DSM 11293 9491804 YP_003805360.1 CDS Spirs_3680 NC_014364.1 3966351 3968609 R COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: tde:TDE2434 polysaccharide deacetylase family protein; PFAM: polysaccharide deacetylase; SPTR: polysaccharide deacetylase family protein; PFAM: polysaccharide deacetylase; polysaccharide deacetylase complement(3966351..3968609) Spirochaeta smaragdinae DSM 11293 9491805 YP_003805361.1 CDS Spirs_3681 NC_014364.1 3968647 3968916 R KEGG: lpj:JDM1_2527 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(3968647..3968916) Spirochaeta smaragdinae DSM 11293 9491806 YP_003805362.1 CDS Spirs_3682 NC_014364.1 3969071 3969868 R COGs: COG1235 metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR000408; KEGG: hor:Hore_11000 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase complement(3969071..3969868) Spirochaeta smaragdinae DSM 11293 9491807 YP_003805363.1 CDS Spirs_3683 NC_014364.1 3969868 3971160 R COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524; KEGG: cbe:Cbei_4224 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; Aminotransferase class I and II; GntR family transcriptional regulator complement(3969868..3971160) Spirochaeta smaragdinae DSM 11293 9491808 YP_003805364.1 CDS Spirs_3684 NC_014364.1 3971307 3972176 D COGs: COG0214 pyridoxine biosynthesis enzyme; InterPro IPR001852; KEGG: mhu:Mhun_2322 pyridoxal biosynthesis lyase PdxS; PFAM: Vitamin B6 biosynthesis protein; SPTR: Vitamin B6 biosynthesis protein; TIGRFAM: pyridoxine biosynthesis protein; PFAM: SOR/SNZ family; TIGRFAM: pyridoxine biosynthesis protein; pyridoxine biosynthesis protein 3971307..3972176 Spirochaeta smaragdinae DSM 11293 9491809 YP_003805365.1 CDS Spirs_3685 NC_014364.1 3972173 3972865 D COGs: COG0311 glutamine amidotransferase involved in pyridoxine biosynthesis; InterPro IPR002161; KEGG: ele:Elen_1110 SNO glutamine amidotransferase; PFAM: SNO glutamine amidotransferase; SPTR: SNO glutamine amidotransferase; PFAM: SNO glutamine amidotransferase family; SNO glutamine amidotransferase 3972173..3972865 Spirochaeta smaragdinae DSM 11293 9491810 YP_003805366.1 CDS Spirs_3686 NC_014364.1 3972780 3974102 R COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR006596:IPR003714; KEGG: ppd:Ppro_2494 PhoH family protein; PFAM: PhoH family protein; SMART: nucleotide binding protein PINc; SPTR: PhoH family protein; PFAM: PhoH-like protein; PhoH family protein complement(3972780..3974102) Spirochaeta smaragdinae DSM 11293 9491811 YP_003805367.1 CDS Spirs_3687 NC_014364.1 3974283 3976034 R COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterProIPR017900:IPR001041:IPR019574:IPR001450:IPR 004108:IPR003149:IPR017896:IPR013352; KEGG: ote:Oter_1544 hydrogenase, Fe-only; PFAM: hydrogenase large subunit domain protein; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; ferredoxin; 4Fe-4S ferredoxin iron-sulfur binding domain protein; iron hydrogenase small subunit; SPTR: hydrogenase, Fe-only; TIGRFAM: hydrogenase, Fe-only; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenases, Fe-only; NAD(P)-dependent iron-only hydrogenase catalytic subunit complement(3974283..3976034) Spirochaeta smaragdinae DSM 11293 9491812 YP_003805368.1 CDS Spirs_3688 NC_014364.1 3976050 3977837 R COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterProIPR017900:IPR001949:IPR011538:IPR019554:IPR 019575:IPR001450:IPR017896; KEGG: ate:Athe_1298 NADH dehydrogenase (quinone); PFAM: Respiratory-chain NADH dehydrogenase domain 51 kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein complement(3976050..3977837) Spirochaeta smaragdinae DSM 11293 9491813 YP_003805369.1 CDS Spirs_3689 NC_014364.1 3977851 3978243 R KEGG: tle:Tlet_1521 NADP-reducing hydrogenase, subunit B; SPTR: NADP-reducing hydrogenase, subunit B; NAD(P)-dependent iron-only hydrogenase iron-sulfur protein complement(3977851..3978243) Spirochaeta smaragdinae DSM 11293 9491814 YP_003805370.1 CDS Spirs_3690 NC_014364.1 3978258 3978809 R COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: dth:DICTH_0767 sensory transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: uncharacterized protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; histidine kinase complement(3978258..3978809) Spirochaeta smaragdinae DSM 11293 9491815 YP_003805371.1 CDS Spirs_3691 NC_014364.1 3978809 3979294 R COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: dtu:Dtur_0916 NADH dehydrogenase (ubiquinone) 24 kDa subunit; PFAM: NADH dehydrogenase (ubiquinone) 24 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone) 24 kDa subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; PFAM: HIRAN domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, E subunit; NADH-quinone oxidoreductase subunit E complement(3978809..3979294) Spirochaeta smaragdinae DSM 11293 9491816 YP_003805372.1 CDS Spirs_3692 NC_014364.1 3979621 3980280 D COGs: COG2344 AT-rich DNA-binding protein; InterPro IPR009718:IPR003781; KEGG: bhy:BHWA1_01894 redox-sensing transcriptional repressor REX; PFAM: CoA-binding protein; Rex DNA-binding domain protein; SPTR: AT-rich DNA-binding protein; PFAM: CoA binding domain; DNA-binding protein N-terminus; CoA-binding protein 3979621..3980280 Spirochaeta smaragdinae DSM 11293 9491817 YP_003805373.1 CDS Spirs_3693 NC_014364.1 3980270 3981127 D COGs: COG1322 conserved hypothetical protein; InterPro IPR003798; KEGG: lpc:LPC_2332 hypothetical protein; PFAM: protein of unknown function DUF195; SPTR: DNA recombination protein; PFAM: RmuC family; TIGRFAM: phage shock protein B; hypothetical protein 3980270..3981127 Spirochaeta smaragdinae DSM 11293 9491818 YP_003805374.1 CDS Spirs_3694 NC_014364.1 3981135 3982226 R InterPro IPR005135; KEGG: tde:TDE2587 endonuclease/exonuclease/phosphatase family protein; PFAM: endonuclease/exonuclease/phosphatase; SPTR: endonuclease/exonuclease/phosphatase family protein; PFAM: endonuclease/exonuclease/phosphatase family; endonuclease/exonuclease/phosphatase complement(3981135..3982226) Spirochaeta smaragdinae DSM 11293 9491819 YP_003805375.1 CDS Spirs_3695 NC_014364.1 3982348 3984279 D COGs: COG1022 Long-chain acyl-CoA synthetase (AMP-forming); InterPro IPR020845:IPR000873; KEGG: pdi:BDI_0615 long-chain-fatty-acid-CoA ligase, PFAM: AMP-dependent synthetase and ligase; SPTR: uncharacterized protein; PFAM: AMP-binding enzyme; AMP-dependent synthetase and ligase 3982348..3984279 Spirochaeta smaragdinae DSM 11293 9491820 YP_003805376.1 CDS Spirs_3696 NC_014364.1 3984311 3985435 D KEGG: pgn:PGN_0374 hypothetical protein; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; hypothetical protein 3984311..3985435 Spirochaeta smaragdinae DSM 11293 9491821 YP_003805377.1 CDS Spirs_3697 NC_014364.1 3985449 3986060 R COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR018215:IPR001907; KEGG: tde:TDE2388 ATP-dependent Clp protease proteolytic subunit; PFAM: peptidase S14 ClpP; PRIAM: endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit 2; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease proteolytic subunit ClpP; endopeptidase Clp complement(3985449..3986060) Spirochaeta smaragdinae DSM 11293 9491822 YP_003805378.1 CDS Spirs_3698 NC_014364.1 3986200 3987084 D COGs: COG1159 GTPase; InterProIPR005662:IPR002917:IPR004044:IPR005225:IPR 006073; KEGG: tde:TDE1895 GTP-binding protein Era; PFAM: GTP-binding protein HSR1-related; KH type 2 domain protein; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; small GTP-binding protein; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain; GTP-binding protein Era 3986200..3987084 Spirochaeta smaragdinae DSM 11293 9491823 YP_003805379.1 CDS Spirs_3699 NC_014364.1 3987099 3988676 R COGs: COG1384 Lysyl-tRNA synthetase (class I); InterPro IPR020756:IPR001412:IPR020754:IPR002904; KEGG: tde:TDE2553 lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase, class Ic; PRIAM: lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; lysyl-tRNA synthetase complement(3987099..3988676) Spirochaeta smaragdinae DSM 11293 9491824 YP_003805380.1 CDS Spirs_3700 NC_014364.1 3988806 3990476 D COGs: COG1283 Na+/phosphate symporter; InterPro IPR003841:IPR008170:IPR004633; KEGG: tde:TDE1964 Na/Pi cotransporter family protein; PFAM: Na+/Picotransporter; PhoU family protein; SPTR: Na/Pi-cotransporter II-related protein, ; TIGRFAM: Na/Pi-cotransporter II-related protein; PFAM: Na+/Pi-cotransporter; PhoU domain; TIGRFAM: Na/Pi-cotransporter; Na/Pi-cotransporter II-like protein 3988806..3990476 Spirochaeta smaragdinae DSM 11293 9491825 YP_003805381.1 CDS Spirs_3701 NC_014364.1 3990473 3991837 R COGs: COG0165 Argininosuccinate lyase; InterPro IPR009049:IPR020557:IPR000362:IPR003031; KEGG: ttr:Tter_0314 argininosuccinate lyase; PFAM: fumarate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: Lyase; TIGRFAM: argininosuccinate lyase; argininosuccinate lyase complement(3990473..3991837) Spirochaeta smaragdinae DSM 11293 9491826 YP_003805382.1 CDS Spirs_3702 NC_014364.1 3992079 3992855 D COGs: COG2014 conserved hypothetical protein; InterPro IPR007161; KEGG: sat:SYN_01176 cytoplasmic protein; PFAM: protein of unknown function DUF364; SPTR: Hypothetical cytosolic protein; PFAM: Domain of unknown function (DUF364); hypothetical protein 3992079..3992855 Spirochaeta smaragdinae DSM 11293 9491827 YP_003805383.1 CDS Spirs_3703 NC_014364.1 3992822 3993370 R KEGG: mta:Moth_2484 cysteinyl-tRNA synthetase; SPTR: Cysteinyl-tRNA synthetase; hypothetical protein complement(3992822..3993370) Spirochaeta smaragdinae DSM 11293 9491828 YP_003805384.1 CDS Spirs_3704 NC_014364.1 3993509 3994462 R COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR001638:IPR015168:IPR010067; KEGG: dat:HRM2_01560 ABC-type transporter substrate-binding protein; PFAM: NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; SPTR: ABC transporter substrate-binding protein, aliphatic sulphonates; TIGRFAM: aliphatic sulfonates family ABC transporter periplsmic ligand-binding protein; PFAM: NMT1/THI5 like; TIGRFAM: ABC transporter substrate-binding protein, aliphatic sulfonates family; aliphatic sulfonates family ABC transporter periplasmic ligand-binding protein complement(3993509..3994462) Spirochaeta smaragdinae DSM 11293 9491829 YP_003805385.1 CDS Spirs_3705 NC_014364.1 3994462 3995229 R COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: drm:Dred_1574 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(3994462..3995229) Spirochaeta smaragdinae DSM 11293 9491830 YP_003805386.1 CDS Spirs_3706 NC_014364.1 3995229 3996002 R COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: drm:Dred_1575 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(3995229..3996002) Spirochaeta smaragdinae DSM 11293 9491831 YP_003805387.1 CDS Spirs_3707 NC_014364.1 3996244 3997425 D COGs: COG2267 lysophospholipase; InterPro IPR000073; KEGG: dal:Dalk_0756 hypothetical protein; PFAM: alpha/beta hydrolase fold; SPTR: uncharacterized protein; PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 3996244..3997425 Spirochaeta smaragdinae DSM 11293 9491832 YP_003805388.1 CDS Spirs_3708 NC_014364.1 3997422 3998147 D COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014284; KEGG: psl:Psta_4074 RNA polymerase, sigma-24 subunit, ECF subfamily; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: Sigma-70 region 2 family protein; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 3997422..3998147 Spirochaeta smaragdinae DSM 11293 9491833 YP_003805389.1 CDS Spirs_3709 NC_014364.1 3998144 3998572 D KEGG: mac:MA2949 hypothetical protein; SPTR: Predicted protein; hypothetical protein 3998144..3998572 Spirochaeta smaragdinae DSM 11293 9491834 YP_003805390.1 CDS Spirs_3710 NC_014364.1 3998708 3999583 D COGs: COG0789 transcriptional regulator protein; InterPro IPR000551; KEGG: smc:SmuNN2025_1444 transcriptional regulator; PFAM: regulatory protein MerR; SMART: regulatory protein MerR; SPTR: transcriptional regulator; PFAM: MerR, DNA binding; MerR family regulatory protein; MerR family transcriptional regulator 3998708..3999583 Spirochaeta smaragdinae DSM 11293 9491835 YP_003805391.1 CDS Spirs_3711 NC_014364.1 3999604 4000758 D COGs: COG3804 conserved hypothetical protein related to dihydrodipicolinate reductase; InterPro IPR000846; KEGG: lhk:LHK_02682 DapB; PFAM: dihydrodipicolinate reductase; SPTR: DapB; dihydrodipicolinate reductase 3999604..4000758 Spirochaeta smaragdinae DSM 11293 9491836 YP_003805392.1 CDS Spirs_3712 NC_014364.1 4000853 4003630 D KEGG: sli:Slin_1741 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4000853..4003630 Spirochaeta smaragdinae DSM 11293 9491837 YP_003805393.1 CDS Spirs_3713 NC_014364.1 4003636 4005462 R COGs: COG0449 glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR000583:IPR001347:IPR017932:IPR005855; KEGG: gau:GAU_2427 glucosamine--fructose-6-phosphate aminotransferase; PFAM: glutamine amidotransferase class-II; sugar isomerase (SIS); SPTR: glucosamine--fructose-6-phosphate aminotransferase; TIGRFAM: glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: SIS domain; glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing); glucosamine/fructose-6-phosphate aminotransferase complement(4003636..4005462) Spirochaeta smaragdinae DSM 11293 9491838 YP_003805394.1 CDS Spirs_3714 NC_014364.1 4005532 4006161 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR018488:IPR000595:IPR002373; KEGG: mxa:MXAN_2702 cyclic nucleotide-binding domain-containing protein; PFAM: cyclic nucleotide-binding; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding domain protein; PFAM: Cyclic nucleotide-binding domain; Crp/Fnr family transcriptional regulator complement(4005532..4006161) Spirochaeta smaragdinae DSM 11293 9491839 YP_003805395.1 CDS Spirs_3715 NC_014364.1 4006222 4007265 D KEGG: mxa:MXAN_5455 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4006222..4007265 Spirochaeta smaragdinae DSM 11293 9491840 YP_003805396.1 CDS Spirs_3716 NC_014364.1 4007271 4007594 R COGs: COG3118 thioredoxin domain-containing protein; InterProIPR017937:IPR013766:IPR017936:IPR005746:IPR 006662; KEGG: tte:TTE1233 thiol-disulfide isomerase and thioredoxins; PFAM: thioredoxin domain; SPTR: thiol-disulfide isomerase and thioredoxins; TIGRFAM: thioredoxin; PFAM: thioredoxin; TIGRFAM: thioredoxin; thioredoxin complement(4007271..4007594) Spirochaeta smaragdinae DSM 11293 9491841 YP_003805397.1 CDS Spirs_3717 NC_014364.1 4007598 4008539 R KEGG: bhy:BHWA1_02653 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4007598..4008539) Spirochaeta smaragdinae DSM 11293 9491842 YP_003805398.1 CDS Spirs_3718 NC_014364.1 4008573 4008995 R COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: hth:HTH_0374 single-stranded DNA-binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; SPTR: Single-stranded DNA-binding protein; TIGRFAM: single-strand binding protein; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb); single-strand binding protein complement(4008573..4008995) Spirochaeta smaragdinae DSM 11293 9491843 YP_003805399.1 CDS Spirs_3719 NC_014364.1 4009112 4009990 D KEGG: tde:TDE0981 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4009112..4009990 Spirochaeta smaragdinae DSM 11293 9491844 YP_003805400.1 CDS Spirs_3720 NC_014364.1 4010268 4011353 R InterPro IPR018247; KEGG: dol:Dole_2458 outer membrane autotransporter; SPTR: porin; hypothetical protein complement(4010268..4011353) Spirochaeta smaragdinae DSM 11293 9491845 YP_003805401.1 CDS Spirs_3721 NC_014364.1 4011577 4012212 D InterPro IPR001647; KEGG: cts:Ctha_1211 transcriptional regulator, TetR family; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 4011577..4012212 Spirochaeta smaragdinae DSM 11293 9491846 YP_003805402.1 CDS Spirs_3722 NC_014364.1 4012321 4015092 D COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR000731:IPR001036; KEGG: tde:TDE2704 hypothetical protein; SPTR: membrane protein; PFAM: MMPL family; hypothetical protein 4012321..4015092 Spirochaeta smaragdinae DSM 11293 9491847 YP_003805403.1 CDS Spirs_3723 NC_014364.1 4015094 4015870 D KEGG: tde:TDE2703 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1329); hypothetical protein 4015094..4015870 Spirochaeta smaragdinae DSM 11293 9491848 YP_003805404.1 CDS Spirs_3724 NC_014364.1 4015880 4017280 D KEGG: tde:TDE2702 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4015880..4017280 Spirochaeta smaragdinae DSM 11293 9491849 YP_003805405.1 CDS Spirs_3725 NC_014364.1 4017316 4017456 D hypothetical protein 4017316..4017456 Spirochaeta smaragdinae DSM 11293 9491850 YP_003805406.1 CDS Spirs_3726 NC_014364.1 4017667 4018275 D InterPro IPR001647; KEGG: fba:FIC_01315 transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 4017667..4018275 Spirochaeta smaragdinae DSM 11293 9491851 YP_003805407.1 CDS Spirs_3727 NC_014364.1 4018398 4021097 D COGs: COG1033 exporter of the RND superfamily protein; InterPro IPR000731:IPR001036; KEGG: tde:TDE2704 hypothetical protein; SPTR: membrane protein, ; PFAM: MMPL family; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; hypothetical protein 4018398..4021097 Spirochaeta smaragdinae DSM 11293 9491852 YP_003805408.1 CDS Spirs_3728 NC_014364.1 4021099 4021875 D KEGG: tde:TDE2703 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1329); sigma E regulatory protein, MucB/RseB 4021099..4021875 Spirochaeta smaragdinae DSM 11293 9491853 YP_003805409.1 CDS Spirs_3729 NC_014364.1 4021885 4023363 D KEGG: tde:TDE2702 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4021885..4023363 Spirochaeta smaragdinae DSM 11293 9491854 YP_003805410.1 CDS Spirs_3730 NC_014364.1 4023624 4024601 R KEGG: esa:ESA_03112 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4023624..4024601) Spirochaeta smaragdinae DSM 11293 9491855 YP_003805411.1 CDS Spirs_3731 NC_014364.1 4024851 4025426 D COGs: COG0655 Multimeric flavodoxin WrbA; InterPro IPR005025; KEGG: mpl:Mpal_1543 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; SPTR: NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; NADPH-dependent FMN reductase 4024851..4025426 Spirochaeta smaragdinae DSM 11293 9491856 YP_003805412.1 CDS Spirs_3732 NC_014364.1 4025423 4026394 D KEGG: bfo:BRAFLDRAFT_125170 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4025423..4026394 Spirochaeta smaragdinae DSM 11293 9491857 YP_003805413.1 CDS Spirs_3733 NC_014364.1 4026447 4027562 R COGs: COG0836 mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR001538; KEGG: gme:Gmet_1104 mannose-1-phosphate guanylyltransferase (GDP); PFAM: nucleotidyl transferase; mannose-6-phosphate isomerase type II; PRIAM: mannose-1-phosphate guanylyltransferase; SPTR: mannose-1-phosphate guanylyltransferase (GDP); PFAM: nucleotidyl transferase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; mannose-1-phosphate guanylyltransferase complement(4026447..4027562) Spirochaeta smaragdinae DSM 11293 9491858 YP_003805414.1 CDS Spirs_3734 NC_014364.1 4027851 4028942 D COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR018300:IPR001544:IPR005786; KEGG: bgr:Bgr_12240 branched-chain amino acid aminotransferase; PFAM: aminotransferase class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid aminotransferase; TIGRFAM: branched-chain amino acid aminotransferase; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II; branched-chain amino acid aminotransferase 4027851..4028942 Spirochaeta smaragdinae DSM 11293 9491859 YP_003805415.1 CDS Spirs_3735 NC_014364.1 4028960 4031956 R COGs: COG5271 ATPase AAA containing von Willebrand factor A (vWA) domain; InterPro IPR019734:IPR013026; KEGG: tde:TDE1092 hypothetical protein; SPTR: uncharacterized protein; von Willebrand factor A complement(4028960..4031956) Spirochaeta smaragdinae DSM 11293 9491860 YP_003805416.1 CDS Spirs_3736 NC_014364.1 4032080 4032883 D InterPro IPR004193; KEGG: tpp:TPASS_0989 protein P26; PFAM: glycoside hydrolase family 13 domain protein; SPTR: uncharacterized protein; PFAM: carbohydrate-binding module 48 (Isoamylase N-terminal domain); glycoside hydrolase family protein 4032080..4032883 Spirochaeta smaragdinae DSM 11293 9491861 YP_003805417.1 CDS Spirs_3737 NC_014364.1 4032867 4033796 R COGs: COG0388 amidohydrolase; InterPro IPR003010; KEGG: kol:Kole_1210 nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; SPTR: nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PFAM: carbon-nitrogen hydrolase; nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase complement(4032867..4033796) Spirochaeta smaragdinae DSM 11293 9491862 YP_003805418.1 CDS Spirs_3738 NC_014364.1 4033800 4034789 R COGs: COG1052 lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: gka:GK1954 dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase complement(4033800..4034789) Spirochaeta smaragdinae DSM 11293 9491863 YP_003805419.1 CDS Spirs_3739 NC_014364.1 4034834 4035466 D COGs: COG1011 hydrolase (HAD superfamily); InterPro IPR005834:IPR006402:IPR005833; KEGG: tpp:TPASS_0158 hypothetical protein; PFAM: haloacid dehalogenase; SPTR: Pyrimidine 5'-nucleotidase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; pyrimidine 5'-nucleotidase; HAD-superfamily hydrolase 4034834..4035466 Spirochaeta smaragdinae DSM 11293 9491864 YP_003805420.1 CDS Spirs_3740 NC_014364.1 4035517 4036584 R COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003593:IPR003439:IPR013563:IPR 010066; KEGG: chl:Chy400_1767 oligopeptide/dipeptide ABC transporter ATPase; PFAM: ABC transporter; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: oligopeptide/dipeptide ABC transporter ATPase; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase complement(4035517..4036584) Spirochaeta smaragdinae DSM 11293 9491865 YP_003805421.1 CDS Spirs_3741 NC_014364.1 4036574 4037875 R COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transporter ATPase component; InterProIPR017871:IPR003593:IPR003439:IPR013563:IPR 010066; KEGG: tvo:TVN1329 ABC-type peptide transporter, ATPase component; PFAM: ABC transporter related; oligopeptide/dipeptide ABC transporter domain protein; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein P1P2A1A2; TIGRFAM: oligopeptide/dipeptide ABC transporter ATPase subunit; PFAM: ABC transporter; oligopeptide/dipeptide transporter C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter ATP-binding protein, C-terminal domain; oligopeptide/dipeptide ABC transporter ATPase complement(4036574..4037875) Spirochaeta smaragdinae DSM 11293 9491866 YP_003805422.1 CDS Spirs_3742 NC_014364.1 4037875 4038834 R COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kcr:Kcr_1095 ABC-type dipeptide/oligopeptide/nickel transporter, permease component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type dipeptide/oligopeptide/nickel transporter, permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4037875..4038834) Spirochaeta smaragdinae DSM 11293 9491867 YP_003805423.1 CDS Spirs_3743 NC_014364.1 4038852 4039886 R COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transporters permeases; InterPro IPR000515; KEGG: kcr:Kcr_1094 ABC-type dipeptide/oligopeptide/nickel transporter, permease component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type dipeptide/oligopeptide/nickel transporter, permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4038852..4039886) Spirochaeta smaragdinae DSM 11293 9491868 YP_003805424.1 CDS Spirs_3744 NC_014364.1 4039982 4041778 R COGs: COG0747 ABC-type dipeptide transporter periplasmic component; InterPro IPR000914; KEGG: kcr:Kcr_1093 ABC-type dipeptide transporter, periplasmic component; PFAM: extracellular solute-binding protein family 5; SPTR: ABC-type dipeptide transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein complement(4039982..4041778) Spirochaeta smaragdinae DSM 11293 9491869 YP_003805425.1 CDS Spirs_3745 NC_014364.1 4041864 4042778 R InterPro IPR000182; KEGG: dal:Dalk_4241 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; Uncharacterised protein family (UPF0158); GCN5-like N-acetyltransferase complement(4041864..4042778) Spirochaeta smaragdinae DSM 11293 9491870 YP_003805426.1 CDS Spirs_3746 NC_014364.1 4042778 4044466 R COGs: COG0442 prolyl-tRNA synthetase; InterProIPR002314:IPR007214:IPR004154:IPR006195:IPR 004500:IPR002316; KEGG: tpt:Tpet_0408 prolyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); YbaK/prolyl-tRNA synthetase associated region; anticodon-binding domain protein; SPTR: prolyl-tRNA synthetase; TIGRFAM: prolyl-tRNA synthetase; manually curated; PFAM: YbaK / prolyl-tRNA synthetases associated domain; anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II; prolyl-tRNA synthetase complement(4042778..4044466) Spirochaeta smaragdinae DSM 11293 9491871 YP_003805427.1 CDS Spirs_3747 NC_014364.1 4044578 4045873 D COGs: COG0148 Enolase; InterPro IPR000941:IPR020809:IPR020811:IPR020810; KEGG: bbz:BbuZS7_0341 phosphopyruvate hydratase; PFAM: Enolase-like; PRIAM: phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: enolase; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase; enolase 4044578..4045873 Spirochaeta smaragdinae DSM 11293 9491872 YP_003805428.1 CDS Spirs_3748 NC_014364.1 4045970 4046245 R COGs: COG1254 acylphosphatase; InterPro IPR017968:IPR001792; KEGG: nca:Noca_4339 acylphosphatase; PFAM: acylphosphatase; SPTR: acylphosphatase; PFAM: acylphosphatase; acylphosphatase complement(4045970..4046245) Spirochaeta smaragdinae DSM 11293 9491873 YP_003805429.1 CDS Spirs_3749 NC_014364.1 4046242 4046610 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: ppw:PputW619_2110 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver modulated metal dependent phosphohydrolase; PFAM: Response regulator receiver domain; response regulator receiver protein complement(4046242..4046610) Spirochaeta smaragdinae DSM 11293 9491874 YP_003805430.1 CDS Spirs_3750 NC_014364.1 4046616 4047221 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; KEGG: tde:TDE0855 DNA-binding response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: DNA-binding response regulator; PFAM: Response regulator receiver domain; TIGRFAM: DNA binding domain, excisionase family; response regulator receiver protein complement(4046616..4047221) Spirochaeta smaragdinae DSM 11293 9491875 YP_003805431.1 CDS Spirs_3751 NC_014364.1 4047286 4047909 R COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: cpb:Cphamn1_2010 regulatory protein RecX; PFAM: regulatory protein RecX; SPTR: Regulatory protein recX; PFAM: RecX family; regulatory protein RecX complement(4047286..4047909) Spirochaeta smaragdinae DSM 11293 9491876 YP_003805432.1 CDS Spirs_3752 NC_014364.1 4047912 4048304 R COGs: COG0103 ribosomal protein S9; InterPro IPR020574:IPR000754; KEGG: tde:TDE0853 30S ribosomal protein S9; PFAM: ribosomal protein S9; SPTR: 30S ribosomal protein S9; PFAM: ribosomal protein S9/S16; 30S ribosomal protein S9 complement(4047912..4048304) Spirochaeta smaragdinae DSM 11293 9491877 YP_003805433.1 CDS Spirs_3753 NC_014364.1 4048324 4048752 R COGs: COG0102 ribosomal protein L13; InterPro IPR005822:IPR005823; KEGG: tro:trd_0954 ribosomal protein L13; PFAM: ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: ribosomal protein L13; PFAM: ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type; 50S ribosomal protein L13 complement(4048324..4048752) Spirochaeta smaragdinae DSM 11293 9491878 YP_003805434.1 CDS Spirs_3754 NC_014364.1 4048951 4049178 D InterPro IPR017896; KEGG: mab:MAB_1213c ferredoxin; SPTR: Conserved domain protein; ferredoxin 4048951..4049178 Spirochaeta smaragdinae DSM 11293 9491879 YP_003805435.1 CDS Spirs_3755 NC_014364.1 4049144 4049443 R KEGG: tde:TDE2375 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4049144..4049443) Spirochaeta smaragdinae DSM 11293 9491880 YP_003805436.1 CDS Spirs_3756 NC_014364.1 4049430 4050335 R InterPro IPR005814; KEGG: tde:TDE2376 hypothetical protein; PFAM: aminotransferase class-III; SPTR: uncharacterized protein; PFAM: Aminotransferase class-III; class III aminotransferase complement(4049430..4050335) Spirochaeta smaragdinae DSM 11293 9491881 YP_003805437.1 CDS Spirs_3757 NC_014364.1 4050325 4052511 R COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR000212:IPR014016:IPR014017; KEGG: tde:TDE2335 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase, UvrD/Rep family; PFAM: UvrD/REP helicase; UvrD/REP helicase complement(4050325..4052511) Spirochaeta smaragdinae DSM 11293 9491882 YP_003805438.1 CDS Spirs_3758 NC_014364.1 4052508 4053833 R COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005840:IPR006638:IPR013848:IPR007197:IPR 005839; KEGG: tde:TDE2609 tRNA modifying protein; PFAM: protein of unknown function UPF0004 ; radical SAM protein; SMART: Elongator protein 3/MiaB/NifB; SPTR: ribosomal protein S12 methylthiotransferase rimO; TIGRFAM: MiaB-like tRNA modifying enzyme YliG; RNA modification enzyme, MiaB family; PFAM: radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme YliG, TIGR01125; RNA modification enzyme, MiaB family; MiaB-like tRNA modifying protein YliG complement(4052508..4053833) Spirochaeta smaragdinae DSM 11293 9491883 YP_003805439.1 CDS Spirs_3759 NC_014364.1 4053840 4054958 R COGs: COG1426 conserved hypothetical protein; InterPro IPR001387; KEGG: tde:TDE2608 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: uncharacterized protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator complement(4053840..4054958) Spirochaeta smaragdinae DSM 11293 9491884 YP_003805440.1 CDS Spirs_3760 NC_014364.1 4054961 4055656 R COGs: COG2834 Outer membrane lipoprotein-sorting protein; InterPro IPR004564; KEGG: tpp:TPASS_0333 hypothetical protein; PFAM: outer membrane lipoprotein carrier protein LolA; SPTR: Outer membrane lipoprotein carrier protein LolA; PFAM: Outer membrane lipoprotein carrier protein LolA; outer membrane lipoprotein carrier protein LolA complement(4054961..4055656) Spirochaeta smaragdinae DSM 11293 9491885 YP_003805441.1 CDS Spirs_3761 NC_014364.1 4055667 4058249 R InterPro IPR019734:IPR001440:IPR013105:IPR013026; KEGG: tde:TDE1687 hypothetical protein; PFAM: Tetratricopeptide TPR_2 repeat protein; hypothetical protein; SPTR: hypothetical protein; hypothetical protein complement(4055667..4058249) Spirochaeta smaragdinae DSM 11293 9491886 YP_003805442.1 CDS Spirs_3762 NC_014364.1 4058335 4059033 D COGs: COG0528 Uridylate kinase; InterPro IPR001048:IPR011818; KEGG: tde:TDE2085 uridylate kinase; PFAM: aspartate/glutamate/uridylate kinase; SPTR: Amino acid kinase family protein; TIGRFAM: uridylate kinase; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase; uridylate kinase 4058335..4059033 Spirochaeta smaragdinae DSM 11293 9491887 YP_003805443.1 CDS Spirs_3763 NC_014364.1 4059042 4059962 R COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterProIPR006162:IPR018114:IPR001989:IPR007197:IPR 016431; KEGG: tde:TDE2506 radical SAM domain-containing protein; PFAM: radical SAM domain protein; SPTR: radical SAM protein; PFAM: radical SAM superfamily; radical SAM protein complement(4059042..4059962) Spirochaeta smaragdinae DSM 11293 9491888 YP_003805444.1 CDS Spirs_3764 NC_014364.1 4060122 4060490 D KEGG: aoe:Clos_2092 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4060122..4060490 Spirochaeta smaragdinae DSM 11293 9491889 YP_003805445.1 CDS Spirs_3765 NC_014364.1 4060465 4060926 D COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR000408:IPR002178; KEGG: rmr:Rmar_1620 PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; PTS IIA-like nitrogen-regulatory protein PtsN 4060465..4060926 Spirochaeta smaragdinae DSM 11293 9491890 YP_003805446.1 CDS Spirs_3766 NC_014364.1 4060923 4061435 D COGs: COG1863 Multisubunit Na+/H+ antiporter MnhE subunit; InterPro IPR002758; KEGG: tsi:TSIB_1917 membrane-bound NADP+-reducing complex MBX, subunit MbxA (Na+/H+ transporter subunit); PFAM: cation antiporter; SPTR: Na+/H+ ion antiporter subunit family; PFAM: Na+/H+ ion antiporter subunit; cation antiporter 4060923..4061435 Spirochaeta smaragdinae DSM 11293 9491891 YP_003805447.1 CDS Spirs_3767 NC_014364.1 4061445 4061738 D InterPro IPR007208; KEGG: abi:Aboo_0665 multiple resistance and pH regulation protein F; PFAM: multiple resistance and pH regulation protein F; SPTR: Multiple resistance and pH regulation protein F; PFAM: Multiple resistance and pH regulation protein F (MrpF / PhaF); multiple resistance and pH regulation protein F 4061445..4061738 Spirochaeta smaragdinae DSM 11293 9491892 YP_003805448.1 CDS Spirs_3768 NC_014364.1 4061735 4062040 D COGs: COG1320 Multisubunit Na+/H+ antiporter MnhG subunit; InterPro IPR005133; KEGG: kol:Kole_0562 monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; SPTR: Monovalent cation/proton antiporter, MnhG/PhaG subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; PFAM: Na+/H+ antiporter subunit; TIGRFAM: monovalent cation/proton antiporter, MnhG/PhaG subunit; monovalent cation/proton antiporter subunit MnhG/PhaG 4061735..4062040 Spirochaeta smaragdinae DSM 11293 9491893 YP_003805449.1 CDS Spirs_3769 NC_014364.1 4062028 4062288 D KEGG: pfu:PF1426 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4062028..4062288 Spirochaeta smaragdinae DSM 11293 9491894 YP_003805450.1 CDS Spirs_3770 NC_014364.1 4062285 4062710 D InterPro IPR007182; KEGG: tsi:TSIB_1290 membrane-bound hydrogenase MBH 2, subunit Mbh2F (Na+/H+ transporter subunit); PFAM: Na+/H+ antiporter Mnhsubunit beta-related protein; SPTR: membrane-bound hydrogenase MBH 2, subunit Mbh2F (Na+/H+ transporter subunit); PFAM: Domain related to MnhB subunit of Na+/H+ antiporter; Na+/H+ antiporter subunit MnhB-like protein 4062285..4062710 Spirochaeta smaragdinae DSM 11293 9491895 YP_003805451.1 CDS Spirs_3771 NC_014364.1 4062997 4064445 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR000014:IPR003594:IPR013656:IPR011495:IPR 005467:IPR001789; KEGG: mth:MTH468 sensory transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; hypothetical protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; SPTR: sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; PAS fold; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 4062997..4064445 Spirochaeta smaragdinae DSM 11293 9491897 YP_003805452.1 CDS Spirs_3772 NC_014364.1 4064519 4064860 R COGs: COG0347 nitrogen regulatory protein PII; InterPro IPR017918:IPR002187; KEGG: fsu:Fisuc_1821 nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; SPTR: nitrogen regulatory protein P-II; PFAM: nitrogen regulatory protein P-II; nitrogen regulatory protein P-II complement(4064519..4064860) Spirochaeta smaragdinae DSM 11293 9491898 YP_003805453.1 CDS Spirs_3773 NC_014364.1 4064874 4066217 R COGs: COG0004 Ammonia permease; InterPro IPR018047:IPR001905; KEGG: dsa:Desal_3066 ammonium transporter; PFAM: ammonium transporter; SPTR: Ammonium transporter; TIGRFAM: ammonium transporter; PFAM: Ammonium transporter Family; TIGRFAM: ammonium transporter; ammonium transporter complement(4064874..4066217) Spirochaeta smaragdinae DSM 11293 9491899 YP_003805454.1 CDS Spirs_3774 NC_014364.1 4066441 4067097 R KEGG: lsl:LSL_0585 IS3 family transposase; SPTR: Predicted protein; hypothetical protein complement(4066441..4067097) Spirochaeta smaragdinae DSM 11293 9491900 YP_003805455.1 CDS Spirs_3775 NC_014364.1 4067192 4069861 R InterPro IPR018247; KEGG: cpi:Cpin_3437 WD-40 repeat protein; SPTR: hypothetical protein; hypothetical protein complement(4067192..4069861) Spirochaeta smaragdinae DSM 11293 9491901 YP_003805456.1 CDS Spirs_3776 NC_014364.1 4069963 4070703 D KEGG: gsu:GSU1295 hypothetical protein; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding proteins, family 3; hypothetical protein 4069963..4070703 Spirochaeta smaragdinae DSM 11293 9491902 YP_003805457.1 CDS Spirs_3777 NC_014364.1 4070709 4072067 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR003594:IPR003660:IPR011495:IPR005467:IPR 004358; KEGG: rci:LRC135 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Predicted signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 4070709..4072067 Spirochaeta smaragdinae DSM 11293 9491903 YP_003805458.1 CDS Spirs_3778 NC_014364.1 4072108 4072956 D COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR018170:IPR001395:IPR020471; KEGG: oih:OB2664 plant-metabolite dehydrogenase; PFAM: aldo/keto reductase; PRIAM: methylglyoxal reductase (NADPH-dependent); SPTR: Plant-metabolite dehydrogenase; manually curated; PFAM: Aldo/keto reductase family; methylglyoxal reductase 4072108..4072956 Spirochaeta smaragdinae DSM 11293 9491904 YP_003805459.1 CDS Spirs_3779 NC_014364.1 4072960 4073502 D InterPro IPR016130:IPR003595:IPR000242:IPR000387; KEGG: tsi:TSIB_1060 protein tyrosine/serine/threonine phosphatase; PFAM: tyrosine specific protein phosphatase; SMART: protein-tyrosine phosphatase, catalytic; SPTR: protein tyrosine/serine/threonine phosphatase; PFAM: Dual specificity phosphatase, catalytic domain; dual specificity protein phosphatase 4072960..4073502 Spirochaeta smaragdinae DSM 11293 9491905 YP_003805460.1 CDS Spirs_3780 NC_014364.1 4073545 4074597 D KEGG: lic:LIC12218 histidine kinase sensor protein; SPTR: sensory transduction histidine kinases; PFAM: histidine kinase; signal transduction histidine kinase 4073545..4074597 Spirochaeta smaragdinae DSM 11293 9491906 YP_003805461.1 CDS Spirs_3781 NC_014364.1 4074658 4074924 D KEGG: nth:Nther_0505 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4074658..4074924 Spirochaeta smaragdinae DSM 11293 9491907 YP_003805462.1 CDS Spirs_3782 NC_014364.1 4074921 4075277 D COGs: COG1006 Multisubunit Na+/H+ antiporter MnhC subunit; InterPro IPR001133; KEGG: amt:Amet_4153 NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone oxidoreductase chain 4L; SPTR: NADH-ubiquinone oxidoreductase, chain 4L; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L; NADH-ubiquinone oxidoreductase chain 4L 4074921..4075277 Spirochaeta smaragdinae DSM 11293 9491908 YP_003805463.1 CDS Spirs_3783 NC_014364.1 4075261 4076976 D COGs: COG0651 formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter MnhD subunit; InterPro IPR001750; KEGG: amt:Amet_4152 NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); SPTR: NADH dehydrogenase (Quinone); PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH/Ubiquinone/plastoquinone (complex I) 4075261..4076976 Spirochaeta smaragdinae DSM 11293 9491909 YP_003805464.1 CDS Spirs_3784 NC_014364.1 4077003 4078850 R COGs: COG0531 Amino acid transporter; InterPro IPR004841:IPR002178; KEGG: hoh:Hoch_4824 amino acid permease-associated region; PFAM: amino acid permease-associated region; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: Amino acid permease-associated region; PFAM: Amino acid permease; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; amino acid permease-associated protein complement(4077003..4078850) Spirochaeta smaragdinae DSM 11293 9491910 YP_003805465.1 CDS Spirs_3785 NC_014364.1 4078882 4079712 R COGs: COG4977 transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain; InterProIPR018062:IPR018060:IPR003313:IPR000005:IPR 020449; KEGG: lba:Lebu_1490 AraC family transcriptional regulator; PFAM: AraC protein arabinose-binding/dimerisation; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator, AraC family; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(4078882..4079712) Spirochaeta smaragdinae DSM 11293 9491911 YP_003805466.1 CDS Spirs_3786 NC_014364.1 4079802 4081142 D COGs: COG2115 Xylose isomerase; InterPro IPR001998:IPR012307:IPR013452; KEGG: rbi:RB2501_04540 xylose isomerase; PFAM: xylose isomerase; PRIAM: Xylose isomerase; SPTR: Xylose isomerase; TIGRFAM: xylose isomerase; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: xylose isomerase; xylose isomerase 4079802..4081142 Spirochaeta smaragdinae DSM 11293 9491912 YP_003805467.1 CDS Spirs_3787 NC_014364.1 4081272 4082201 D KEGG: rpd:RPD_2736 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4081272..4082201 Spirochaeta smaragdinae DSM 11293 9491913 YP_003805468.1 CDS Spirs_3788 NC_014364.1 4082198 4083196 D KEGG: mno:Mnod_0096 adenylate/guanylate cyclase; SPTR: adenylate cyclase 3; hypothetical protein 4082198..4083196 Spirochaeta smaragdinae DSM 11293 9491914 YP_003805469.1 CDS Spirs_3789 NC_014364.1 4083248 4084087 D COGs: COG1876 D-alanyl-D-alanine carboxypeptidase; InterPro IPR003709; KEGG: tde:TDE0633 D-alanyl-D-alanine carboxypeptidase, PFAM: peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin; SPTR: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; PFAM: D-alanyl-D-alanine carboxypeptidase; peptidase M15B and M15C DD-carboxypeptidase VanY/endolysin 4083248..4084087 Spirochaeta smaragdinae DSM 11293 9491915 YP_003805470.1 CDS Spirs_3790 NC_014364.1 4084088 4084930 R KEGG: sma:SAV_7144 secreted protein; SPTR: uncharacterized protein; hypothetical protein complement(4084088..4084930) Spirochaeta smaragdinae DSM 11293 9491916 YP_003805471.1 CDS Spirs_3791 NC_014364.1 4084927 4086660 R KEGG: noc:Noc_2170 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4084927..4086660) Spirochaeta smaragdinae DSM 11293 9491917 YP_003805472.1 CDS Spirs_3792 NC_014364.1 4086657 4088030 R KEGG: nhl:Nhal_3624 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4086657..4088030) Spirochaeta smaragdinae DSM 11293 9491918 YP_003805473.1 CDS Spirs_3793 NC_014364.1 4088148 4088651 R KEGG: rfr:Rfer_2715 VCBS; SPTR: uncharacterized protein; hypothetical protein complement(4088148..4088651) Spirochaeta smaragdinae DSM 11293 9491919 YP_003805474.1 CDS Spirs_3794 NC_014364.1 4088841 4089335 R KEGG: rso:RSc0115 hemagglutinin-related protein; SPTR: Probable hemagglutinin-related autotransporter protein; hypothetical protein complement(4088841..4089335) Spirochaeta smaragdinae DSM 11293 9491920 YP_003805475.1 CDS Spirs_3795 NC_014364.1 4089357 4090040 R KEGG: tde:TDE1324 hypothetical protein; SPTR: uncharacterized protein; PFAM: FecR protein; hypothetical protein complement(4089357..4090040) Spirochaeta smaragdinae DSM 11293 9491921 YP_003805476.1 CDS Spirs_3796 NC_014364.1 4090055 4091233 R KEGG: tde:TDE1327 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4090055..4091233) Spirochaeta smaragdinae DSM 11293 9491922 YP_003805477.1 CDS Spirs_3797 NC_014364.1 4091230 4091661 R KEGG: tde:TDE1328 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4091230..4091661) Spirochaeta smaragdinae DSM 11293 9491923 YP_003805478.1 CDS Spirs_3798 NC_014364.1 4091843 4094566 D COGs: COG2114 adenylate cyclase family 3 (some protein contain HAMP domain); InterPro IPR001901:IPR001054:IPR007890; KEGG: tde:TDE0932 adenylate/guanylate cyclase catalytic domain-containing protein; PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; CHASE2 domain protein; SMART: adenylyl cyclase class-3/4/guanylyl cyclase; SPTR: adenylate/guanylate cyclase catalytic domain protein; PFAM: adenylate and Guanylate cyclase catalytic domain; CHASE2 domain; adenylate/guanylate cyclase with Chase sensor 4091843..4094566 Spirochaeta smaragdinae DSM 11293 9491924 YP_003805479.1 CDS Spirs_3799 NC_014364.1 4094579 4095313 D InterPro IPR002198:IPR005122; KEGG: dat:HRM2_39870 SmuG; PFAM: uracil-DNA glycosylase superfamily; SPTR: SmuG; PFAM: uracil DNA glycosylase superfamily; uracil-DNA glycosylase superfamily protein 4094579..4095313 Spirochaeta smaragdinae DSM 11293 9491925 YP_003805480.1 CDS Spirs_3800 NC_014364.1 4095342 4096967 D COGs: COG0513 Superfamily II DNA and RNA helicase; InterProIPR000629:IPR014001:IPR001650:IPR011545:IPR 014021:IPR014014; KEGG: dal:Dalk_2316 DEAD/DEAH box helicase domain protein; PFAM: DEAD/DEAH box helicase; helicase domain protein; SMART: DEAD-like helicase ; helicase; SPTR: ATP-dependent RNA helicase DbpA; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; DEAD/DEAH box helicase 4095342..4096967 Spirochaeta smaragdinae DSM 11293 9491926 YP_003805481.1 CDS Spirs_3801 NC_014364.1 4096981 4097925 D COGs: COG1597 Sphingosine kinase; InterPro IPR001206:IPR005218; KEGG: rca:Rcas_2760 diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase; SMART: diacylglycerol kinase catalytic region; SPTR: diacylglycerol kinase catalytic region; PFAM: diacylglycerol kinase catalytic domain; TIGRFAM: conserved protein of unknown function cotranscribed with Bmr (bmrU); diacylglycerol kinase 4096981..4097925 Spirochaeta smaragdinae DSM 11293 9491927 YP_003805482.1 CDS Spirs_3802 NC_014364.1 4097922 4098617 D COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: tro:trd_0439 acyltransferase domain protein; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: acyltransferase domain protein; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase 4097922..4098617 Spirochaeta smaragdinae DSM 11293 9491928 YP_003805483.1 CDS Spirs_3803 NC_014364.1 4098610 4099278 D COGs: COG0560 phosphoserine phosphatase; InterPro IPR006385; KEGG: mab:MAB_0431c hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; TIGRFAM: HAD-superfamily subfamily IB hydrolase, TIGR01490; Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; HAD superfamily hydrolase 4098610..4099278 Spirochaeta smaragdinae DSM 11293 9491929 YP_003805484.1 CDS Spirs_3804 NC_014364.1 4099286 4100833 D COGs: COG0554 glycerol kinase; InterPro IPR018483:IPR018484:IPR018485; KEGG: lic:LIC10629 glycerol kinase; PFAM: carbohydrate kinase, FGGY-like; SPTR: glycerol kinase; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase; carbohydrate kinase FGGY 4099286..4100833 Spirochaeta smaragdinae DSM 11293 9491930 YP_003805485.1 CDS Spirs_3805 NC_014364.1 4100842 4101576 D COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: cbt:CLH_3257 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; phospholipid/glycerol acyltransferase 4100842..4101576 Spirochaeta smaragdinae DSM 11293 9491931 YP_003805486.1 CDS Spirs_3806 NC_014364.1 4101604 4102158 D KEGG: min:Minf_2394 dTDP-glucose pyrophosphorylase; SPTR: glucose-1-phosphate thymidylyltransferase; hypothetical protein 4101604..4102158 Spirochaeta smaragdinae DSM 11293 9491932 YP_003805487.1 CDS Spirs_3807 NC_014364.1 4102286 4104604 R COGs: COG1752 esterase of the alpha-beta hydrolase superfamily; InterPro IPR002641; KEGG: tmz:Tmz1t_1473 patatin; PFAM: patatin; SPTR: patatin; PFAM: patatin-like phospholipase; patatin complement(4102286..4104604) Spirochaeta smaragdinae DSM 11293 9491933 YP_003805488.1 CDS Spirs_3808 NC_014364.1 4104706 4106049 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR003660:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: bpf:BpOF4_20474 two component system histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase complement(4104706..4106049) Spirochaeta smaragdinae DSM 11293 9491934 YP_003805489.1 CDS Spirs_3809 NC_014364.1 4106053 4106736 R COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR005829:IPR001789:IPR001867; KEGG: csc:Csac_2559 two component transcriptional regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; SMART: response regulator receiver; SPTR: Two component transcriptional regulator, winged helix family; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator complement(4106053..4106736) Spirochaeta smaragdinae DSM 11293 9491935 YP_003805490.1 CDS Spirs_3810 NC_014364.1 4106887 4108203 D COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827; KEGG: ade:Adeh_1155 outer membrane protein/protective antigen OMA87-like; PFAM: surface antigen variable number repeat protein; SPTR: Surface antigen variable number repeat domain protein; surface antigen variable number repeat protein 4106887..4108203 Spirochaeta smaragdinae DSM 11293 9491936 YP_003805491.1 CDS Spirs_3811 NC_014364.1 4108234 4109283 D COGs: COG0845 membrane-fusion protein; InterPro IPR006143; KEGG: cts:Ctha_2722 efflux transporter RND family, MFP subunit; SPTR: uncharacterized protein; TIGRFAM: efflux transporter RND family, MFP subunit; TIGRFAM: RND family efflux transporter MFP subunit; RND family efflux transporter MFP subunit 4108234..4109283 Spirochaeta smaragdinae DSM 11293 9491937 YP_003805492.1 CDS Spirs_3812 NC_014364.1 4109293 4112385 D COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: cts:Ctha_2723 acriflavin resistance protein; PFAM: acriflavin resistance protein; SPTR: Acriflavin resistance protein; PFAM: AcrB/AcrD/AcrF family; acriflavin resistance protein 4109293..4112385 Spirochaeta smaragdinae DSM 11293 9491938 YP_003805493.1 CDS Spirs_3813 NC_014364.1 4112388 4113749 D COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: cts:Ctha_2724 outer membrane efflux protein; PFAM: outer membrane efflux protein; SPTR: Outer membrane efflux protein; PFAM: Outer membrane efflux protein; outer membrane efflux protein 4112388..4113749 Spirochaeta smaragdinae DSM 11293 9491939 YP_003805494.1 CDS Spirs_3814 NC_014364.1 4113827 4114756 R COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: sth:STH108 hypothetical protein; PFAM: rhodanese; SMART: rhodanese; SPTR: Rhodanese; PFAM: Rhodanese-like domain; rhodanese complement(4113827..4114756) Spirochaeta smaragdinae DSM 11293 9491940 YP_003805495.1 CDS Spirs_3815 NC_014364.1 4114786 4115709 R COGs: COG2897 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: glo:Glov_1161 rhodanese domain protein; PFAM: rhodanese; SMART: rhodanese; SPTR: rhodanese-like protein; PFAM: Rhodanese-like domain; rhodanese complement(4114786..4115709) Spirochaeta smaragdinae DSM 11293 9491941 YP_003805496.1 CDS Spirs_3816 NC_014364.1 4115779 4117518 D COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; KEGG: gtn:GTNG_3085 hypothetical protein; SPTR: uncharacterized protein; 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family 4115779..4117518 Spirochaeta smaragdinae DSM 11293 9491942 YP_003805497.1 CDS Spirs_3817 NC_014364.1 4117391 4118143 R COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: azc:AZC_2715 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(4117391..4118143) Spirochaeta smaragdinae DSM 11293 9491943 YP_003805498.1 CDS Spirs_3818 NC_014364.1 4118143 4118898 R COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: mno:Mnod_0055 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4118143..4118898) Spirochaeta smaragdinae DSM 11293 9491944 YP_003805499.1 CDS Spirs_3819 NC_014364.1 4118895 4119887 R COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR017985:IPR015168; KEGG: sth:STH1653 ABC transporter substrate-binding protein; PFAM: NMT1/THI5 like domain protein; SPTR: ABC transporter substrate-binding protein; PFAM: NMT1/THI5 like; NMT1/THI5 like domain-containing protein complement(4118895..4119887) Spirochaeta smaragdinae DSM 11293 9491945 YP_003805500.1 CDS Spirs_3820 NC_014364.1 4119884 4121926 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173:IPR011761; KEGG: cdl:CDR20291_0245 carbamoyl-phosphate-synthetase; PFAM: glycosyl transferase family 2; SPTR: carbamoyl-phosphate-synthetase; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4119884..4121926) Spirochaeta smaragdinae DSM 11293 9491946 YP_003805501.1 CDS Spirs_3821 NC_014364.1 4121923 4122300 R KEGG: hmo:HM1_0451 small multidrug resistance transmembrane protein, SPTR: Small multidrug resistance transmembrane protein, ; PFAM: EamA-like transporter family; small multidrug resistance transmembrane protein complement(4121923..4122300) Spirochaeta smaragdinae DSM 11293 9491947 YP_003805502.1 CDS Spirs_3822 NC_014364.1 4122297 4122689 R InterPro IPR000620; KEGG: bcb:BCB4264_A5060 transporter; PFAM: protein of unknown function DUF6 transmembrane; SPTR: uncharacterized protein; PFAM: EamA-like transporter family; hypothetical protein complement(4122297..4122689) Spirochaeta smaragdinae DSM 11293 9491948 YP_003805503.1 CDS Spirs_3823 NC_014364.1 4122673 4125072 R COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR003593:IPR002543:IPR018541; KEGG: tde:TDE0173 FtsK/SpoIIIE family protein; PFAM: cell divisionFtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: ATPase AAA; SPTR: DNA translocase ftsk; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family; cell division protein FtsK/SpoIIIE complement(4122673..4125072) Spirochaeta smaragdinae DSM 11293 9491949 YP_003805504.1 CDS Spirs_3824 NC_014364.1 4125165 4125959 R COGs: COG1968 Uncharacterized bacitracin resistance protein; InterPro IPR003824; KEGG: tde:TDE0172 undecaprenyl pyrophosphate phosphatase; PFAM: bacitracin resistance protein BacA; SPTR: undecaprenyl-diphosphatase; PFAM: bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP; bacitracin resistance protein BacA complement(4125165..4125959) Spirochaeta smaragdinae DSM 11293 9491950 YP_003805505.1 CDS Spirs_3825 NC_014364.1 4125982 4128189 R COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: tpp:TPASS_0043 soluble lytic transglycosylase; PFAM: lytic transglycosylase catalytic; SPTR: Soluble lytic transglycosylase, ; PFAM: transglycosylase SLT domain; lytic transglycosylase complement(4125982..4128189) Spirochaeta smaragdinae DSM 11293 9491951 YP_003805506.1 CDS Spirs_3826 NC_014364.1 4128155 4129072 R InterPro IPR002482:IPR018392; KEGG: tde:TDE2281 LysM domain-containing protein; PFAM: peptidoglycan-binding lysin domain; SMART: peptidoglycan-binding LysM; SPTR: LysM domain protein; PFAM: Hsp70 protein; LysM domain; peptidoglycan-binding lysin domain-containing protein complement(4128155..4129072) Spirochaeta smaragdinae DSM 11293 9491952 YP_003805507.1 CDS Spirs_3827 NC_014364.1 4129174 4130535 D InterProIPR019734:IPR013105:IPR001440:IPR007560:IPR 013026; KEGG: tpp:TPASS_0915 hypothetical protein; PFAM: restriction endonuclease; hypothetical protein; TPR repeat-containing protein; SMART: Tetratricopeptide repeat; SPTR: TPR domain protein; PFAM: Restriction endonuclease; restriction endonuclease 4129174..4130535 Spirochaeta smaragdinae DSM 11293 9491953 YP_003805508.1 CDS Spirs_3828 NC_014364.1 4130504 4131175 R COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: hha:Hhal_0001 methyltransferase GidB; PFAM: glucose inhibited division protein; SPTR: ribosomal RNA small subunit methyltransferase G; TIGRFAM: methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA methyltransferase GidB; methyltransferase GidB complement(4130504..4131175) Spirochaeta smaragdinae DSM 11293 9491954 YP_003805509.1 CDS Spirs_3829 NC_014364.1 4131172 4133031 R COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; InterPro IPR004416:IPR020595:IPR002218; KEGG: bhr:BH0178 tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; PFAM: glucose-inhibited division protein A; SPTR: tRNA (5-carboxymethylaminomethyl-2-thiouridylate) synthase subunit GidA; TIGRFAM: glucose inhibited division protein A; PFAM: glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A; glucose inhibited division protein A complement(4131172..4133031) Spirochaeta smaragdinae DSM 11293 9491955 YP_003805510.1 CDS Spirs_3830 NC_014364.1 4133050 4134420 R COGs: COG0486 GTPase; InterPro IPR004520:IPR018948:IPR002917:IPR005225; KEGG: bbz:BbuZS7_0179 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE-like; GTP-binding protein HSR1-related; SPTR: tRNA modification GTPase TrmE; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: tRNA modification GTPase TrmE; small GTP-binding protein domain; tRNA modification GTPase TrmE complement(4133050..4134420) Spirochaeta smaragdinae DSM 11293 9491956 YP_003805511.1 CDS Spirs_3831 NC_014364.1 4134567 4135652 D InterPro IPR013217; KEGG: mta:Moth_1421 O-methyltransferase family protein; PFAM: methyltransferase type 12; SPTR: O-methyltransferase, family 2; PFAM: O-methyltransferase; type 12 methyltransferase 4134567..4135652 Spirochaeta smaragdinae DSM 11293 9491957 YP_003805512.1 CDS Spirs_3832 NC_014364.1 4135682 4136536 D COGs: COG2014 conserved hypothetical protein; InterPro IPR007161; KEGG: mbn:Mboo_2364 hypothetical protein; PFAM: protein of unknown function DUF364; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF364); hypothetical protein 4135682..4136536 Spirochaeta smaragdinae DSM 11293 9491958 YP_003805513.1 CDS Spirs_3833 NC_014364.1 4136550 4137617 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: mta:Moth_1422 periplasmic binding protein; PFAM: periplasmic binding protein; SPTR: Periplasmic binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 4136550..4137617 Spirochaeta smaragdinae DSM 11293 9491959 YP_003805514.1 CDS Spirs_3834 NC_014364.1 4137659 4138678 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: mhu:Mhun_2017 transporter permease; PFAM: transporter permease; SPTR: transport system permease; PFAM: FecCD transport family; transporter permease 4137659..4138678 Spirochaeta smaragdinae DSM 11293 9491960 YP_003805515.1 CDS Spirs_3835 NC_014364.1 4138726 4139526 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR017871:IPR003593:IPR003439; KEGG: mba:Mbar_A2262 iron(III) ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Iron(III) ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 4138726..4139526 Spirochaeta smaragdinae DSM 11293 9491961 YP_003805516.1 CDS Spirs_3836 NC_014364.1 4139533 4140264 R KEGG: syp:SYNPCC7002_G0120 hypothetical protein; SPTR: Conserved hypothetical membrane protein; hypothetical protein complement(4139533..4140264) Spirochaeta smaragdinae DSM 11293 9491962 YP_003805517.1 CDS Spirs_3837 NC_014364.1 4140264 4141190 R COGs: COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductase; InterPro IPR002328:IPR013154:IPR013149; KEGG: bmq:BMQ_3328 oxidoreductase, zinc-binding dehydrogenase family; PFAM: alcohol dehydrogenase zinc-binding domain protein; alcohol dehydrogenase GroES domain protein; SPTR: oxidoreductase; PFAM: alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase; alcohol dehydrogenase zinc-binding domain-containing protein complement(4140264..4141190) Spirochaeta smaragdinae DSM 11293 9491963 YP_003805518.1 CDS Spirs_3838 NC_014364.1 4141569 4141820 R KEGG: ctc:CTC01384 membrane spanning protein; SPTR: membrane spanning protein; membrane spanning protein complement(4141569..4141820) Spirochaeta smaragdinae DSM 11293 9491964 YP_003805519.1 CDS Spirs_3839 NC_014364.1 4141893 4142315 D KEGG: cth:Cthe_1015 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4141893..4142315 Spirochaeta smaragdinae DSM 11293 9491965 YP_003805520.1 CDS Spirs_3840 NC_014364.1 4142543 4143424 D COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR011063:IPR005232; KEGG: cbi:CLJ_B0142 conserved hypothetical protein TIGR00268; PFAM: PP-loop domain protein; SPTR: uncharacterized protein; PFAM: Asparagine synthase; TIGRFAM: conserved hypothetical protein TIGR00268; PP-loop domain-containing protein 4142543..4143424 Spirochaeta smaragdinae DSM 11293 9491966 YP_003805521.1 CDS Spirs_3841 NC_014364.1 4143437 4144675 D COGs: COG1641 conserved hypothetical protein; InterPro IPR002822; KEGG: sat:SYN_00476 hypothetical protein; PFAM: protein of unknown function DUF111; SPTR: Hypothetical cytosolic protein; PFAM: protein of unknown function DUF111; TIGRFAM: conserved hypothetical protein TIGR00299; hypothetical protein 4143437..4144675 Spirochaeta smaragdinae DSM 11293 9491967 YP_003805522.1 CDS Spirs_3842 NC_014364.1 4144672 4145448 D COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: sat:SYN_00474 phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; SPTR: phosphoribosylaminoimidazole carboxylase NCAIR mutase subunit; PFAM: AIR carboxylase; 1-(5-phosphoribosyl)-5-amino-4-imidazole- carboxylate (AIR) carboxylase 4144672..4145448 Spirochaeta smaragdinae DSM 11293 9491968 YP_003805523.1 CDS Spirs_3843 NC_014364.1 4145441 4146292 D InterPro IPR013216; KEGG: mmz:MmarC7_1469 methyltransferase type 11; PFAM: methyltransferase type 11; SPTR: methyltransferase type 11; PFAM: ribosomal RNA adenine dimethylase; type 11 methyltransferase 4145441..4146292 Spirochaeta smaragdinae DSM 11293 9491969 YP_003805524.1 CDS Spirs_3844 NC_014364.1 4146282 4147481 D COGs: COG0614 ABC-type Fe3+-hydroxamate transporter periplasmic component; InterPro IPR002491; KEGG: mba:Mbar_A1176 ABC transporter solute-binding protein; PFAM: periplasmic binding protein; SPTR: ABC transporter substrate-binding protein; PFAM: Periplasmic binding protein; periplasmic binding protein 4146282..4147481 Spirochaeta smaragdinae DSM 11293 9491970 YP_003805525.1 CDS Spirs_3845 NC_014364.1 4147471 4148502 D COGs: COG0609 ABC-type Fe3+-siderophore transporter permease; InterPro IPR000522; KEGG: mac:MA1131 iron ABC transporter permease; PFAM: transporter permease; SPTR: Iron ABC transporter permease; PFAM: FecCD transport family; transporter permease 4147471..4148502 Spirochaeta smaragdinae DSM 11293 9491971 YP_003805526.1 CDS Spirs_3846 NC_014364.1 4148513 4149268 D COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transporters ATPase components; InterPro IPR017871:IPR003593:IPR003439; KEGG: mba:Mbar_A1172 iron ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Iron ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 4148513..4149268 Spirochaeta smaragdinae DSM 11293 9491972 YP_003805527.1 CDS Spirs_3847 NC_014364.1 4149374 4151962 D COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR005467:IPR 004358; KEGG: cyc:PCC7424_0118 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; integral membrane sensor hybrid histidine kinase 4149374..4151962 Spirochaeta smaragdinae DSM 11293 9491973 YP_003805528.1 CDS Spirs_3848 NC_014364.1 4151955 4153079 D COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789:IPR011495; KEGG: dma:DMR_10920 two-component hybrid sensor and regulator; PFAM: response regulator receiver; histidine kinase dimerisation/phosphoacceptor; SMART: response regulator receiver; SPTR: Two-component hybrid sensor and regulator; PFAM: histidine kinase; Response regulator receiver domain; response regulator receiver protein 4151955..4153079 Spirochaeta smaragdinae DSM 11293 9491974 YP_003805529.1 CDS Spirs_3849 NC_014364.1 4153105 4154415 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: hvo:HVO_0165 chlorohydrolase family protein; PFAM: amidohydrolase; SPTR: chlorohydrolase family protein; PFAM: Amidohydrolase family; amidohydrolase complement(4153105..4154415) Spirochaeta smaragdinae DSM 11293 9491975 YP_003805530.1 CDS Spirs_3850 NC_014364.1 4154412 4155143 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: rrs:RoseRS_0542 short-chain dehydrogenase/reductase SDR; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(4154412..4155143) Spirochaeta smaragdinae DSM 11293 9491976 YP_003805531.1 CDS Spirs_3851 NC_014364.1 4155183 4156025 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: tit:Thit_0424 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4155183..4156025) Spirochaeta smaragdinae DSM 11293 9491977 YP_003805532.1 CDS Spirs_3852 NC_014364.1 4156028 4156876 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: tex:Teth514_0396 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Sugar ABC transporter permease; manually curated; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4156028..4156876) Spirochaeta smaragdinae DSM 11293 9491978 YP_003805533.1 CDS Spirs_3853 NC_014364.1 4157011 4158303 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: sme:SM_b21221 sugar uptake ABC transporter periplasmic solute-binding protein precursor; PFAM: extracellular solute-binding protein family 1; SPTR: ABC sugar transporter periplasmic ligand binding protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(4157011..4158303) Spirochaeta smaragdinae DSM 11293 9491979 YP_003805534.1 CDS Spirs_3854 NC_014364.1 4158602 4159255 R COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR000792:IPR001789; KEGG: amt:Amet_1559 two component LuxR family transcriptional regulator; PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: Two component LuxR family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator complement(4158602..4159255) Spirochaeta smaragdinae DSM 11293 9491980 YP_003805535.1 CDS Spirs_3855 NC_014364.1 4159233 4160474 R COGs: COG4585 Signal transduction histidine kinase; InterPro IPR005479:IPR003594:IPR011712; KEGG: cbi:CLJ_B1493 sensor histidine kinase; PFAM: histidine kinase dimerisation and phosphoacceptor region; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(4159233..4160474) Spirochaeta smaragdinae DSM 11293 9491981 YP_003805536.1 CDS Spirs_3856 NC_014364.1 4160575 4161084 R KEGG: gbr:Gbro_4611 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SPTR: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; hypothetical protein complement(4160575..4161084) Spirochaeta smaragdinae DSM 11293 9491982 YP_003805537.1 CDS Spirs_3857 NC_014364.1 4161235 4161717 D COGs: COG1803 methylglyoxal synthase; InterPro IPR004363:IPR018148:IPR011607; KEGG: sfu:Sfum_2894 methylglyoxal synthase; PFAM: MGS domain protein; PRIAM: methylglyoxal synthase; SPTR: methylglyoxal synthase; TIGRFAM: methylglyoxal synthase; PFAM: MGS-like domain; TIGRFAM: methylglyoxal synthase; methylglyoxal synthase 4161235..4161717 Spirochaeta smaragdinae DSM 11293 9491983 YP_003805538.1 CDS Spirs_3858 NC_014364.1 4161807 4162904 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 4161807..4162904 Spirochaeta smaragdinae DSM 11293 9491984 YP_003805539.1 CDS Spirs_3860 NC_014364.1 4163235 4164122 D COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: dsy:DSY0819 hypothetical protein; PFAM: Integrase catalytic region; SPTR: uncharacterized protein; PFAM: Integrase core domain; Integrase catalytic subunit 4163235..4164122 Spirochaeta smaragdinae DSM 11293 9491986 YP_003805540.1 CDS Spirs_3861 NC_014364.1 4164243 4165682 R KEGG: mta:Moth_2225 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4164243..4165682) Spirochaeta smaragdinae DSM 11293 9491987 YP_003805541.1 CDS Spirs_3862 NC_014364.1 4165679 4166164 R InterPro IPR000182; KEGG: vha:VIBHAR_06850 acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase complement(4165679..4166164) Spirochaeta smaragdinae DSM 11293 9491988 YP_003805542.1 CDS Spirs_3863 NC_014364.1 4166161 4167018 R COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: bwe:BcerKBAB4_5507 von Willebrand factor A; PFAM: von Willebrand factor A; SPTR: Vancomycin B-type resistance protein vanW; PFAM: VanW like protein; von Willebrand factor A complement(4166161..4167018) Spirochaeta smaragdinae DSM 11293 9491989 YP_003805543.1 CDS Spirs_3864 NC_014364.1 4167031 4168179 R InterPro IPR000421:IPR010900; KEGG: lbf:LBF_0675 hypothetical protein; PFAM: nicotine adenine dinucleotide glycohydrolase; coagulation factor 5/8 type domain protein; SPTR: uncharacterized protein; PFAM: nicotine adenine dinucleotide glycohydrolase (NADase); nicotine adenine dinucleotide glycohydrolase complement(4167031..4168179) Spirochaeta smaragdinae DSM 11293 9491990 YP_003805544.1 CDS Spirs_3865 NC_014364.1 4168292 4169377 R COGs: COG3839 ABC-type sugar transporters ATPase components; InterPro IPR017871:IPR003593:IPR003439:IPR013611; KEGG: tna:CTN_0249 sugar ABC transporter ATP-binding protein; PFAM: ABC transporter related; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: Sugar ABC transporter ATP-binding protein; PFAM: ABC transporter; TOBE domain; ABC transporter complement(4168292..4169377) Spirochaeta smaragdinae DSM 11293 9491991 YP_003805545.1 CDS Spirs_3866 NC_014364.1 4169390 4170259 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: rxy:Rxyl_2069 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4169390..4170259) Spirochaeta smaragdinae DSM 11293 9491992 YP_003805546.1 CDS Spirs_3867 NC_014364.1 4170271 4171185 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: rxy:Rxyl_2070 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4170271..4171185) Spirochaeta smaragdinae DSM 11293 9491993 YP_003805547.1 CDS Spirs_3868 NC_014364.1 4171256 4172647 R COGs: COG2182 maltose-binding periplasmic protein/domains; InterPro IPR006059; KEGG: rxy:Rxyl_2071 twin-arginine translocation pathway signal; PFAM: extracellular solute-binding protein family 1; SPTR: Twin-arginine translocation pathway signal; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein complement(4171256..4172647) Spirochaeta smaragdinae DSM 11293 9491994 YP_003805548.1 CDS Spirs_3869 NC_014364.1 4172754 4173740 D COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: dth:DICTH_0016 transcriptional regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator 4172754..4173740 Spirochaeta smaragdinae DSM 11293 9491995 YP_003805549.1 CDS Spirs_3870 NC_014364.1 4173762 4174439 D COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129:IPR000909; KEGG: dps:DP0335 glcerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: Probable glcerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase family; glycerophosphoryl diester phosphodiesterase 4173762..4174439 Spirochaeta smaragdinae DSM 11293 9491996 YP_003805550.1 CDS Spirs_3871 NC_014364.1 4174452 4175321 R COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: clo:HMPREF0868_0372 hypothetical protein; PFAM: PfkB domain protein; SPTR: uncharacterized protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein complement(4174452..4175321) Spirochaeta smaragdinae DSM 11293 9491997 YP_003805551.1 CDS Spirs_3872 NC_014364.1 4175345 4176106 R COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: pjd:Pjdr2_2906 glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphoryl diester phosphodiesterase; PFAM: glycerophosphoryl diester phosphodiesterase family; glycerophosphoryl diester phosphodiesterase complement(4175345..4176106) Spirochaeta smaragdinae DSM 11293 9491998 YP_003805552.1 CDS Spirs_3873 NC_014364.1 4176106 4176942 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: ddc:Dd586_0844 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4176106..4176942) Spirochaeta smaragdinae DSM 11293 9491999 YP_003805553.1 CDS Spirs_3874 NC_014364.1 4176939 4177817 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: hch:HCH_03297 ABC-type sugar transport system, permeases; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC-type sugar transporter, permease components; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4176939..4177817) Spirochaeta smaragdinae DSM 11293 9492000 YP_003805554.1 CDS Spirs_3875 NC_014364.1 4177913 4179184 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: hch:HCH_03296 ABC-type sugar transport system, periplasmic component; PFAM: extracellular solute-binding protein family 1; SPTR: ABC-type sugar transporter, periplasmic component; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(4177913..4179184) Spirochaeta smaragdinae DSM 11293 9492001 YP_003805555.1 CDS Spirs_3876 NC_014364.1 4179332 4180297 D KEGG: cgb:cg2115 transcriptional regulators of sugar metabolism, DeoR family; SPTR: transcriptional regulators of sugar metabolism; DeoR family transcriptional regulator 4179332..4180297 Spirochaeta smaragdinae DSM 11293 9492002 YP_003805556.1 CDS Spirs_3877 NC_014364.1 4180326 4180790 D InterPro IPR000182; KEGG: dap:Dacet_2510 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4180326..4180790 Spirochaeta smaragdinae DSM 11293 9492003 YP_003805557.1 CDS Spirs_3878 NC_014364.1 4180873 4181241 D KEGG: dap:Dacet_1955 hypothetical protein; SPTR: uncharacterized protein; PFAM: rubrerythrin; hypothetical protein 4180873..4181241 Spirochaeta smaragdinae DSM 11293 9492004 YP_003805558.1 CDS Spirs_3879 NC_014364.1 4181250 4182047 D COGs: COG1659 conserved hypothetical protein; InterPro IPR007544; KEGG: dap:Dacet_1956 Linocin_M18 bacteriocin protein; PFAM: Linocin_M18 bacteriocin protein; SPTR: Linocin_M18 bacteriocin protein; PFAM: Encapsulating protein for peroxidase; Linocin_M18 bacteriocin protein 4181250..4182047 Spirochaeta smaragdinae DSM 11293 9492005 YP_003805559.1 CDS Spirs_3880 NC_014364.1 4182267 4182650 R COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: rer:RER_15410 HxlR family transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: transcriptional regulator; PFAM: HxlR-like helix-turn-helix; HxlR family transcriptional regulator complement(4182267..4182650) Spirochaeta smaragdinae DSM 11293 9492006 YP_003805560.1 CDS Spirs_3881 NC_014364.1 4182777 4183625 D COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR008030; KEGG: predicted nucleoside-diphosphate sugar epimerase; PFAM: NmrA family protein; SPTR: Predicted nucleoside-diphosphate sugar epimerase; PFAM: NmrA-like family; NmrA family protein 4182777..4183625 Spirochaeta smaragdinae DSM 11293 9492007 YP_003805561.1 CDS Spirs_3882 NC_014364.1 4183864 4184676 R COGs: COG3384 conserved hypothetical protein; InterPro IPR004183:IPR014436; KEGG: dat:HRM2_39660 LigB; PFAM: extradiol ring-cleavage dioxygenase class III protein subunit B; SPTR: extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; PFAM: Catalytic Ligsubunit beta of aromatic ring-opening dioxygenase; extradiol ring-cleavage dioxygenase class III protein subunit B complement(4183864..4184676) Spirochaeta smaragdinae DSM 11293 9492008 YP_003805562.1 CDS Spirs_3883 NC_014364.1 4184727 4185557 R COGs: COG1737 transcriptional regulators; InterPro IPR000281:IPR001347; KEGG: smd:Smed_4018 RpiR family transcriptional regulator; PFAM: helix-turn-helix protein RpiR; sugar isomerase (SIS); SPTR: RpiR family transcriptional regulator; PFAM: Helix-turn-helix domain, rpiR family; SIS domain; RpiR family transcriptional regulator complement(4184727..4185557) Spirochaeta smaragdinae DSM 11293 9492009 YP_003805563.1 CDS Spirs_3884 NC_014364.1 4185617 4186441 R InterPro IPR009825:IPR010387; KEGG: tex:Teth514_1877 hypothetical protein; PFAM: protein of unknown function DUF988; protein of unknown function DUF1393; SPTR: uncharacterized protein; PFAM: QueT transporter; hypothetical protein complement(4185617..4186441) Spirochaeta smaragdinae DSM 11293 9492010 YP_003805564.1 CDS Spirs_3885 NC_014364.1 4186495 4187298 R COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: tpd:Teth39_0881 cobalt transporter; PFAM: cobalt transporter; SPTR: Cobalt transporter; PFAM: Cobalt transporter; cobalt transporter complement(4186495..4187298) Spirochaeta smaragdinae DSM 11293 9492011 YP_003805565.1 CDS Spirs_3886 NC_014364.1 4187300 4189012 R COGs: COG1123 ATPase components of various ABC-type transporters contain duplicated ATPase; InterPro IPR017871:IPR003593:IPR003439; KEGG: tpd:Teth39_0880 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; TIGRFAM: cobalt transporter ATP-binding subunit; ABC transporter complement(4187300..4189012) Spirochaeta smaragdinae DSM 11293 9492012 YP_003805566.1 CDS Spirs_3887 NC_014364.1 4189134 4190183 R COGs: COG0182 translation initiation factor 2subunit beta eIF-2B alpha/beta/delta family; InterPro IPR000649:IPR011559; KEGG: amt:Amet_3757 methylthioribose-1-phosphate isomerase; PFAM: initiation factor 2B related; PRIAM: S-methyl-5-thioribose-1-phosphate isomerase; SPTR: uncharacterized protein; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized protein; PFAM: Initiation factor 2 subunit family; TIGRFAM: eIF-2B alpha/beta/delta-related uncharacterized proteins; eIF-2B alpha/beta/delta-like protein complement(4189134..4190183) Spirochaeta smaragdinae DSM 11293 9492013 YP_003805567.1 CDS Spirs_3888 NC_014364.1 4190305 4191543 R KEGG: deb:DehaBAV1_1284 extracellular solute-binding protein; SPTR: peptide ABC transporter periplasmic peptide-binding protein; hypothetical protein complement(4190305..4191543) Spirochaeta smaragdinae DSM 11293 9492014 YP_003805568.1 CDS Spirs_3889 NC_014364.1 4191540 4192373 R KEGG: hor:Hore_23220 sigma E regulatory protein, MucB/RseB; SPTR: sigma E regulatory protein, MucB/RseB; hypothetical protein complement(4191540..4192373) Spirochaeta smaragdinae DSM 11293 9492015 YP_003805569.1 CDS Spirs_3890 NC_014364.1 4192370 4193656 R COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838; KEGG: hor:Hore_23230 ABC-type transporter, involved in lipoprotein release, permease; PFAM: protein of unknown function DUF214; SPTR: ABC-type transporter, involved in lipoprotein release, permease; PFAM: Predicted permease; hypothetical protein complement(4192370..4193656) Spirochaeta smaragdinae DSM 11293 9492016 YP_003805570.1 CDS Spirs_3891 NC_014364.1 4193668 4195362 R COGs: COG4591 ABC-type transporter involved in lipoprotein release permease; InterPro IPR003838; KEGG: hor:Hore_23270 ABC-type transporter, involved in lipoprotein release, permease; PFAM: protein of unknown function DUF214; SPTR: ABC-type transporter, involved in lipoprotein release, permease; PFAM: Predicted permease; hypothetical protein complement(4193668..4195362) Spirochaeta smaragdinae DSM 11293 9492017 YP_003805571.1 CDS Spirs_3892 NC_014364.1 4195359 4196042 R COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: rmr:Rmar_2536 ABC transporter; PFAM: ABC transporter related; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(4195359..4196042) Spirochaeta smaragdinae DSM 11293 9492018 YP_003805572.1 CDS Spirs_3893 NC_014364.1 4196029 4197135 R COGs: COG0330 membrane protease subunits stomatin/prohibitin homologs; InterPro IPR001107:IPR001972; KEGG: sus:acid_1595 SPFH domain-containing protein/band 7 family protein; PFAM: band 7 protein; SMART: band 7 protein; SPTR: Band 7 protein; PFAM: SPFH domain / Band 7 family; band 7 protein complement(4196029..4197135) Spirochaeta smaragdinae DSM 11293 9492019 YP_003805573.1 CDS Spirs_3894 NC_014364.1 4197132 4197533 R COGs: COG1725 transcriptional regulator protein; InterPro IPR000524; KEGG: sus:acid_1594 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator complement(4197132..4197533) Spirochaeta smaragdinae DSM 11293 9492020 YP_003805574.1 CDS Spirs_3895 NC_014364.1 4197635 4198660 D COGs: COG3920 Signal transduction histidine kinase; InterPro IPR003594:IPR011495; KEGG: cts:Ctha_0145 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Signal transduction histidine kinase; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 4197635..4198660 Spirochaeta smaragdinae DSM 11293 9492021 YP_003805575.1 CDS Spirs_3896 NC_014364.1 4198657 4199034 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: azl:AZL_b02970 two-component hybrid sensor and regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Two-component hybrid sensor and regulator; PFAM: Response regulator receiver domain; response regulator receiver protein 4198657..4199034 Spirochaeta smaragdinae DSM 11293 9492022 YP_003805576.1 CDS Spirs_3897 NC_014364.1 4199094 4199666 R KEGG: oaa:100074041 hypothetical protein LOC100074041; SPTR: uncharacterized protein; hypothetical protein complement(4199094..4199666) Spirochaeta smaragdinae DSM 11293 9492023 YP_003805577.1 CDS Spirs_3898 NC_014364.1 4199704 4200093 R KEGG: cpr:CPR_0311 calcium-translocating P-type ATPase, PMCA-type; SPTR: PX; hypothetical protein complement(4199704..4200093) Spirochaeta smaragdinae DSM 11293 9492024 YP_003805578.1 CDS Spirs_3899 NC_014364.1 4200090 4201655 R InterPro IPR002345:IPR013378:IPR019501; KEGG: slg:SLGD_00154 hypothetical protein; PFAM: Listeria/Bacterioides repeat protein; peptidase M30, hyicolysin; SPTR: uncharacterized protein; TIGRFAM: cell wall/surface repeat protein; PFAM: Listeria-Bacteroides repeat domain (List_Bact_rpt); peptidase M30; TIGRFAM: Listeria/Bacterioides repeat; cell wall/surface repeat protein complement(4200090..4201655) Spirochaeta smaragdinae DSM 11293 9492025 YP_003805579.1 CDS Spirs_3900 NC_014364.1 4201899 4202930 R COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: ace:Acel_1421 peptidase M48, Ste24p; PFAM: peptidase M48 Ste24p; SPTR: peptidase M48, Ste24p; PFAM: peptidase family M48; peptidase M48 Ste24p complement(4201899..4202930) Spirochaeta smaragdinae DSM 11293 9492026 YP_003805580.1 CDS Spirs_3901 NC_014364.1 4202935 4204767 R COGs: COG1217 membrane GTPase involved in stress response; InterProIPR000795:IPR004161:IPR000640:IPR005225:IPR 006298; KEGG: dsa:Desal_3190 GTP-binding protein TypA; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain protein; SPTR: GTP-binding protein TypA; TIGRFAM: GTP-binding protein TypA; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain; GTP-binding protein TypA complement(4202935..4204767) Spirochaeta smaragdinae DSM 11293 9492027 YP_003805581.1 CDS Spirs_3902 NC_014364.1 4204866 4205291 D KEGG: tcr:509269.4 Tb-291 membrane-associated protein-like; SPTR: Tb-291 membrane-associated protein-like; Tb-291 membrane-associated protein 4204866..4205291 Spirochaeta smaragdinae DSM 11293 9492028 YP_003805582.1 CDS Spirs_3903 NC_014364.1 4205288 4206097 D COGs: COG0584 glycerophosphoryl diester phosphodiesterase; InterPro IPR004129; KEGG: tde:TDE0799 glycerophosphoryl diester phosphodiesterase, PFAM: glycerophosphoryl diester phosphodiesterase; SPTR: glycerophosphoryl diester phosphodiesterase, ; PFAM: glycerophosphoryl diester phosphodiesterase family; glycerophosphoryl diester phosphodiesterase 4205288..4206097 Spirochaeta smaragdinae DSM 11293 9492029 YP_003805583.1 CDS Spirs_3904 NC_014364.1 4206106 4207587 R KEGG: tde:TDE0730 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4206106..4207587) Spirochaeta smaragdinae DSM 11293 9492030 YP_003805584.1 CDS Spirs_3905 NC_014364.1 4207589 4208971 R KEGG: tde:TDE0732 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4207589..4208971) Spirochaeta smaragdinae DSM 11293 9492031 YP_003805585.1 CDS Spirs_3906 NC_014364.1 4208986 4210287 R KEGG: tde:TDE0733 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4208986..4210287) Spirochaeta smaragdinae DSM 11293 9492032 YP_003805586.1 CDS Spirs_3907 NC_014364.1 4210377 4211714 R KEGG: afv:AFLA_103650 aldose 1-epimerase, SPTR: Predicted mutarotase; hypothetical protein complement(4210377..4211714) Spirochaeta smaragdinae DSM 11293 9492033 YP_003805587.1 CDS Spirs_3908 NC_014364.1 4211777 4212895 R InterPro IPR006860; KEGG: lic:LIC10387 hypothetical protein; PFAM: FecR protein; SPTR: uncharacterized protein; PFAM: FecR protein; anti-FecI sigma factor FecR complement(4211777..4212895) Spirochaeta smaragdinae DSM 11293 9492034 YP_003805588.1 CDS Spirs_3909 NC_014364.1 4212952 4214223 R COGs: COG2195 Di- and tripeptidase; InterPro IPR001261:IPR002933:IPR011650:IPR010161; KEGG: tva:TVAG_379940 Clan MH, family M20, peptidase T-like metallopeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein; PRIAM: Tripeptide aminopeptidase; SPTR: Clan MH, family M20, peptidase T-like metallopeptidase; TIGRFAM: peptidase T; manually curated; PFAM: peptidase family M20/M25/M40; TIGRFAM: peptidase T; peptidase T complement(4212952..4214223) Spirochaeta smaragdinae DSM 11293 9492035 YP_003805589.1 CDS Spirs_3910 NC_014364.1 4214352 4215221 D COGs: COG4866 conserved hypothetical protein; InterPro IPR016732; KEGG: dat:HRM2_23720 hypothetical protein; PFAM: Uncharacterised conserved protein UCP018688; SPTR: uncharacterized protein; PFAM: Uncharacterized conserved protein (DUF2156); hypothetical protein 4214352..4215221 Spirochaeta smaragdinae DSM 11293 9492036 YP_003805590.1 CDS Spirs_3911 NC_014364.1 4215414 4217549 D COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: cbe:Cbei_0444 glutamine synthetase, catalytic region; PFAM: glutamine synthetase catalytic region; SPTR: glutamine synthetase; PFAM: glutamine synthetase, catalytic domain; glutamine synthetase type III N terminal; glutamine synthetase 4215414..4217549 Spirochaeta smaragdinae DSM 11293 9492037 YP_003805591.1 CDS Spirs_3912 NC_014364.1 4217635 4218822 R COGs: COG1167 transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: pab:PAB2227 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Multiple substrate aminotransferase; PFAM: Aminotransferase class I and II; GntR family transcriptional regulator complement(4217635..4218822) Spirochaeta smaragdinae DSM 11293 9492038 YP_003805592.1 CDS Spirs_3913 NC_014364.1 4218868 4220607 R COGs: COG0475 Kef-type K+ transporters membrane components; InterPro IPR006153; KEGG: bre:BRE_449 Na+/H+ antiporter; PFAM: sodium/hydrogen exchanger; SPTR: Na+ /H+ antiporter; PFAM: Sodium/hydrogen exchanger family; sodium/hydrogen exchanger complement(4218868..4220607) Spirochaeta smaragdinae DSM 11293 9492039 YP_003805593.1 CDS Spirs_3914 NC_014364.1 4220620 4221060 R COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: tde:TDE0062 PTS system, IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: PTS system, IIA component; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose subfamily, IIA component; PTS IIA-like nitrogen-regulatory protein PtsN complement(4220620..4221060) Spirochaeta smaragdinae DSM 11293 9492040 YP_003805594.1 CDS Spirs_3915 NC_014364.1 4221096 4222703 R COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003594:IPR005467:IPR004358; KEGG: ppd:Ppro_0904 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; integral membrane sensor signal transduction histidine kinase complement(4221096..4222703) Spirochaeta smaragdinae DSM 11293 9492041 YP_003805595.1 CDS Spirs_3916 NC_014364.1 4222704 4223486 R KEGG: bdu:BDU_632 hypothetical protein; SPTR: Uncharacterized conserved protein; hypothetical protein complement(4222704..4223486) Spirochaeta smaragdinae DSM 11293 9492042 YP_003805596.1 CDS Spirs_3917 NC_014364.1 4223507 4224673 D COGs: COG5505 integral membrane protein; InterPro IPR008537; KEGG: sil:SPOA0019 hypothetical protein; PFAM: protein of unknown function DUF819; SPTR: membrane protein, ; PFAM: protein of unknown function (DUF819); hypothetical protein 4223507..4224673 Spirochaeta smaragdinae DSM 11293 9492043 YP_003805597.1 CDS Spirs_3918 NC_014364.1 4224709 4225686 R COGs: COG1957 inosine-uridine nucleoside N-ribohydrolase; InterPro IPR015910:IPR001910; KEGG: lba:Lebu_1571 purine nucleosidase; PFAM: inosine/uridine-preferring nucleoside hydrolase; SPTR: uncharacterized protein; PFAM: inosine-uridine preferring nucleoside hydrolase; inosine/uridine-preferring nucleoside hydrolase complement(4224709..4225686) Spirochaeta smaragdinae DSM 11293 9492044 YP_003805598.1 CDS Spirs_3919 NC_014364.1 4225715 4227037 R COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: nth:Nther_1148 N-ethylammeline chlorohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase complement(4225715..4227037) Spirochaeta smaragdinae DSM 11293 9492045 YP_003805599.1 CDS Spirs_3920 NC_014364.1 4227040 4227813 R COGs: COG2820 Uridine phosphorylase; InterPro IPR018016:IPR000845; KEGG: str:Sterm_0544 purine or other phosphorylase family 1; PFAM: purine or other phosphorylase family 1; SPTR: uncharacterized protein; PFAM: phosphorylase superfamily; TIGRFAM: uridine phosphorylase; purine or other phosphorylase family 1 complement(4227040..4227813) Spirochaeta smaragdinae DSM 11293 9492046 YP_003805600.1 CDS Spirs_3921 NC_014364.1 4227850 4229040 R COGs: COG0738 Fucose permease; InterPro IPR011701; KEGG: spq:SPAB_01973 hypothetical protein; PFAM: major facilitator superfamily MFS_1; SPTR: MFS family major facilitator transporter; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein complement(4227850..4229040) Spirochaeta smaragdinae DSM 11293 9492047 YP_003805601.1 CDS Spirs_3922 NC_014364.1 4229037 4229852 R COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR003593:IPR003439; KEGG: gym:GYMC10_6248 ABC transporter related protein; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related protein; PFAM: ABC transporter; ABC transporter complement(4229037..4229852) Spirochaeta smaragdinae DSM 11293 9492048 YP_003805602.1 CDS Spirs_3923 NC_014364.1 4229862 4230713 R COGs: COG1122 ABC-type cobalt transporter ATPase component; InterPro IPR017871:IPR003593:IPR003439; KEGG: gym:GYMC10_6247 ABC transporter related protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(4229862..4230713) Spirochaeta smaragdinae DSM 11293 9492049 YP_003805603.1 CDS Spirs_3924 NC_014364.1 4230704 4231459 R COGs: COG0619 ABC-type cobalt transporter permease component CbiQ and related transporter; InterPro IPR003339; KEGG: gym:GYMC10_6246 cobalt transporter; PFAM: cobalt transporter; SPTR: uncharacterized protein; PFAM: Cobalt transporter; cobalt transporter complement(4230704..4231459) Spirochaeta smaragdinae DSM 11293 9492050 YP_003805604.1 CDS Spirs_3925 NC_014364.1 4231562 4232197 R KEGG: lba:Lebu_0306 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1393); signal transduction histidine kinase LytS complement(4231562..4232197) Spirochaeta smaragdinae DSM 11293 9492051 YP_003805605.1 CDS Spirs_3926 NC_014364.1 4232285 4233028 R COGs: COG2188 transcriptional regulators; InterPro IPR000524; KEGG: tit:Thit_0434 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; GntR family transcriptional regulator complement(4232285..4233028) Spirochaeta smaragdinae DSM 11293 9492052 YP_003805606.1 CDS Spirs_3927 NC_014364.1 4233190 4233750 D COGs: COG5418 secreted protein; InterPro IPR019274; KEGG: cbh:CLC_1547 hypothetical protein; PFAM: protein of unknown function DUF2297; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF523); hypothetical protein 4233190..4233750 Spirochaeta smaragdinae DSM 11293 9492053 YP_003805607.1 CDS Spirs_3928 NC_014364.1 4233880 4234788 D COGs: COG1715 Restriction endonuclease; InterPro IPR007560; KEGG: ana:alr7132 mrr restriction system protein; PFAM: restriction endonuclease; SPTR: Mrr restriction system protein; PFAM: Restriction endonuclease; restriction endonuclease 4233880..4234788 Spirochaeta smaragdinae DSM 11293 9492054 YP_003805608.1 CDS Spirs_3929 NC_014364.1 4234829 4235590 D COGs: COG2226 methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: bhy:BHWA1_02457 methyltransferase; PFAM: methyltransferase type 11; SPTR: methyltransferase; PFAM: methyltransferase domain; type 11 methyltransferase 4234829..4235590 Spirochaeta smaragdinae DSM 11293 9492055 YP_003805609.1 CDS Spirs_3930 NC_014364.1 4235644 4236072 D InterPro IPR000182; KEGG: vap:Vapar_1348 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4235644..4236072 Spirochaeta smaragdinae DSM 11293 9492056 YP_003805610.1 CDS Spirs_3931 NC_014364.1 4236080 4236958 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dol:Dole_0985 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase family 2; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4236080..4236958) Spirochaeta smaragdinae DSM 11293 9492057 YP_003805611.1 CDS Spirs_3932 NC_014364.1 4236977 4237456 R KEGG: rce:RC1_4001 alkaline protease SPTR: uncharacterized protein; hypothetical protein complement(4236977..4237456) Spirochaeta smaragdinae DSM 11293 9492058 YP_003805612.1 CDS Spirs_3933 NC_014364.1 4237453 4243989 R InterPro IPR008619; KEGG: sml:Smlt1009 glycine-rich autotransporter protein; PFAM: Haemagluttinin repeat-containing protein; SPTR: Outer membrane autotransporter barrel domain protein; Hemagluttinin repeat-containing protein complement(4237453..4243989) Spirochaeta smaragdinae DSM 11293 9492059 YP_003805613.1 CDS Spirs_3934 NC_014364.1 4243986 4248941 R InterPro IPR001969:IPR008619; KEGG: bcj:BCAS0321 hypothetical glycine-rich autotransporter protein; PFAM: Haemagluttinin repeat-containing protein; SPTR: Outer membrane autotransporter barrel domain protein; Hemagluttinin repeat-containing protein complement(4243986..4248941) Spirochaeta smaragdinae DSM 11293 9492060 YP_003805614.1 CDS Spirs_3935 NC_014364.1 4249034 4249939 R KEGG: mbr:MONBRDRAFT_33649 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4249034..4249939) Spirochaeta smaragdinae DSM 11293 9492061 YP_003805615.1 CDS Spirs_3936 NC_014364.1 4249932 4250717 R COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: bpf:BpOF4_10720 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short chain dehydrogenase; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(4249932..4250717) Spirochaeta smaragdinae DSM 11293 9492062 YP_003805616.1 CDS Spirs_3937 NC_014364.1 4250759 4251694 R InterPro IPR006124; KEGG: rmr:Rmar_1180 metalloenzyme domain protein; PFAM: metalloenzyme domain protein; SPTR: metalloenzyme domain protein; PFAM: metalloenzyme superfamily; metalloenzyme domain-containing protein complement(4250759..4251694) Spirochaeta smaragdinae DSM 11293 9492063 YP_003805617.1 CDS Spirs_3938 NC_014364.1 4251684 4253216 R KEGG: taf:THA_1948 tryptophan synthase subunit beta; SPTR: DNA primase (Bacterial type); hypothetical protein complement(4251684..4253216) Spirochaeta smaragdinae DSM 11293 9492064 YP_003805618.1 CDS Spirs_3939 NC_014364.1 4253251 4254543 D COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR006264:IPR001986:IPR016228; KEGG: cth:Cthe_3086 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; 3-phosphoshikimate 1-carboxyvinyltransferase 4253251..4254543 Spirochaeta smaragdinae DSM 11293 9492065 YP_003805619.1 CDS Spirs_3940 NC_014364.1 4254557 4255588 D COGs: COG2008 threonine aldolase; InterPro IPR001597; KEGG: bhy:BHWA1_00425 L-allo-threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: threonine aldolase; SPTR: threonine aldolase; PFAM: beta-eliminating lyase; threonine aldolase 4254557..4255588 Spirochaeta smaragdinae DSM 11293 9492066 YP_003805620.1 CDS Spirs_3941 NC_014364.1 4255592 4256161 R KEGG: afn:Acfer_0870 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4255592..4256161) Spirochaeta smaragdinae DSM 11293 9492067 YP_003805621.1 CDS Spirs_3942 NC_014364.1 4256233 4257174 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR002173:IPR011611; KEGG: nca:Noca_4622 ribokinase-like domain-containing protein; PFAM: PfkB domain protein; SPTR: PfkB domain protein; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 4256233..4257174 Spirochaeta smaragdinae DSM 11293 9492068 YP_003805622.1 CDS Spirs_3943 NC_014364.1 4257161 4258105 D COGs: COG2313 Uncharacterized protein involved in pigment biosynthesis; InterPro IPR007342; KEGG: tte:TTE0327 uncharacterized enzyme involved in pigment biosynthesis; PFAM: indigoidine synthase A family protein; SPTR: Pseudouridine-5'-phosphate glycosidase; PFAM: indigoidine synthase A like protein; indigoidine synthase A family protein 4257161..4258105 Spirochaeta smaragdinae DSM 11293 9492069 YP_003805623.1 CDS Spirs_3944 NC_014364.1 4258110 4261523 R COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR000212:IPR014016:IPR014017; KEGG: tde:TDE0085 ATP-dependent DNA helicase UvrD; PFAM: UvrD/REP helicase; SPTR: ATP-dependent DNA helicase, UvrD/Rep family; PFAM: UvrD/REP helicase; UvrD/REP helicase complement(4258110..4261523) Spirochaeta smaragdinae DSM 11293 9492070 YP_003805624.1 CDS Spirs_3945 NC_014364.1 4261514 4264213 R KEGG: tde:TDE0086 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4261514..4264213) Spirochaeta smaragdinae DSM 11293 9492071 YP_003805625.1 CDS Spirs_3946 NC_014364.1 4264224 4264751 R COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; KEGG: amu:Amuc_0597 hypothetical protein; SPTR: uncharacterized protein; PFAM: Flavin reductase like domain; hypothetical protein complement(4264224..4264751) Spirochaeta smaragdinae DSM 11293 9492072 YP_003805626.1 CDS Spirs_3947 NC_014364.1 4264833 4266428 D COGs: COG0840 methyl-accepting chemotaxis protein; InterProIPR003660:IPR004089:IPR013163:IPR000727:IPR 004090; KEGG: dvm:DvMF_1869 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache type 2 domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis sensory transducer with Cache sensor; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 4264833..4266428 Spirochaeta smaragdinae DSM 11293 9492073 YP_003805627.1 CDS Spirs_3948 NC_014364.1 4266412 4267200 D COGs: COG1028 dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR002347; KEGG: hch:HCH_00126 short-chain alcohol dehydrogenase-like protein; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain alcohol dehydrogenase-like protein; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR 4266412..4267200 Spirochaeta smaragdinae DSM 11293 9492074 YP_003805628.1 CDS Spirs_3949 NC_014364.1 4267207 4267818 D COGs: COG2095 Multiple antibiotic transporter; InterPro IPR002771; KEGG: pab:PAB2220 hypothetical protein; PFAM: multiple antibiotic resistance (MarC)-related protein; SPTR: UPF0056 membrane protein PYRAB02000; PFAM: MarC family integral membrane protein; TIGRFAM: conserved hypothetical protein TIGR00427; multiple antibiotic resistance (MarC)-like protein 4267207..4267818 Spirochaeta smaragdinae DSM 11293 9492075 YP_003805629.1 CDS Spirs_3950 NC_014364.1 4267915 4268322 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 4267915..4268322 Spirochaeta smaragdinae DSM 11293 9492076 YP_003805630.1 CDS Spirs_3951 NC_014364.1 4268352 4268627 D InterPro IPR002514; KEGG: dsy:DSY0820 hypothetical protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase; PFAM: transposase; transposase IS3/IS911 family protein 4268352..4268627 Spirochaeta smaragdinae DSM 11293 9492077 YP_003805631.1 CDS Spirs_3952 NC_014364.1 4268639 4269526 D COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: dsy:DSY0819 hypothetical protein; PFAM: Integrase catalytic region; SPTR: uncharacterized protein; PFAM: Integrase core domain; Integrase catalytic subunit 4268639..4269526 Spirochaeta smaragdinae DSM 11293 9492078 YP_003805632.1 CDS Spirs_3953 NC_014364.1 4269687 4270316 D KEGG: ptm:GSPATT00017706001 hypothetical protein; SPTR: chromosome undetermined scaffold_53, whole genome shotgun sequence; hypothetical protein 4269687..4270316 Spirochaeta smaragdinae DSM 11293 9492079 YP_003805633.1 CDS Spirs_3954 NC_014364.1 4270376 4271548 D COGs: COG2205 osmosensitive K+ channel histidine kinase; InterPro IPR003661:IPR003594:IPR005467:IPR004358; KEGG: hau:Haur_4061 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 4270376..4271548 Spirochaeta smaragdinae DSM 11293 9492080 YP_003805634.1 CDS Spirs_3955 NC_014364.1 4271541 4272239 D COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: tma:TM1655 response regulator DrrA; PFAM: response regulator receiver; transcriptional regulator; SMART: response regulator receiver; SPTR: Response regulator DrrA; PFAM: Response regulator receiver domain; transcriptional regulatory protein, C terminal; winged helix family two component transcriptional regulator 4271541..4272239 Spirochaeta smaragdinae DSM 11293 9492081 YP_003805635.1 CDS Spirs_3956 NC_014364.1 4272334 4273362 D COGs: COG1840 ABC-type Fe3+ transporter periplasmic component; InterPro IPR006059; KEGG: kol:Kole_1985 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; family 1 extracellular solute-binding protein 4272334..4273362 Spirochaeta smaragdinae DSM 11293 9492082 YP_003805636.1 CDS Spirs_3957 NC_014364.1 4273434 4275119 D COGs: COG1178 ABC-type Fe3+ transporter permease component; InterPro IPR000515; KEGG: kol:Kole_1984 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 4273434..4275119 Spirochaeta smaragdinae DSM 11293 9492083 YP_003805637.1 CDS Spirs_3958 NC_014364.1 4275131 4276222 D COGs: COG3842 ABC-type spermidine/putrescine transport systems ATPase components; InterPro IPR017871:IPR003593:IPR003439:IPR013611; KEGG: ctc:CTC00276 iron(III)-transport ATP-binding protein SfuC; PFAM: ABC transporter; transport-associated OB domain protein; SMART: ATPase AAA; SPTR: Iron(III)-transport ATP-binding protein sfuC; PFAM: ABC transporter; TOBE domain; ABC transporter 4275131..4276222 Spirochaeta smaragdinae DSM 11293 9492084 YP_003805638.1 CDS Spirs_3959 NC_014364.1 4276257 4277726 D KEGG: ddf:DEFDS_1656 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4276257..4277726 Spirochaeta smaragdinae DSM 11293 9492085 YP_003805639.1 CDS Spirs_3960 NC_014364.1 4277791 4279146 D COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR000644:IPR001667; KEGG: sth:STH1805 poly A polymerase; PFAM: CBS domain containing protein; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; SPTR: poly A polymerase; PFAM: DHH family; CBS domain; CBS domain containing protein 4277791..4279146 Spirochaeta smaragdinae DSM 11293 9492086 YP_003805640.1 CDS Spirs_3961 NC_014364.1 4279160 4280539 R COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: ctc:CTC00419 Na+ driven multidrug efflux pump; PFAM: multi antimicrobial extrusion protein MatE; SPTR: MATE efflux family protein; TIGRFAM: MATE efflux family protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; MATE efflux family protein complement(4279160..4280539) Spirochaeta smaragdinae DSM 11293 9492087 YP_003805641.1 CDS Spirs_3962 NC_014364.1 4280529 4281125 R InterPro IPR001647; KEGG: cbl:CLK_0533 TetR family transcriptional regulator; PFAM: regulatory protein TetR; SPTR: transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator complement(4280529..4281125) Spirochaeta smaragdinae DSM 11293 9492088 YP_003805642.1 CDS Spirs_3963 NC_014364.1 4281173 4282234 R COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523:IPR004488; KEGG: gme:Gmet_1189 magnesium/cobalt transporter CorA; PFAM: Mg2 transporter protein CorA family protein; SPTR: Magnesium and cobalt transporter CorA; TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: CorA-like Mg2+ transporter protein; TIGRFAM: magnesium Mg(2+) and cobalt Co(2+) transporter (corA); magnesium and cobalt transporter CorA complement(4281173..4282234) Spirochaeta smaragdinae DSM 11293 9492089 YP_003805643.1 CDS Spirs_3964 NC_014364.1 4282259 4282558 R InterPro IPR001789; KEGG: gsu:GSU1928 sensor histidine kinase/response regulator; SPTR: Sensor protein; response regulator receiver protein complement(4282259..4282558) Spirochaeta smaragdinae DSM 11293 9492090 YP_003805644.1 CDS Spirs_3965 NC_014364.1 4282694 4283023 D InterPro IPR001387; KEGG: bbt:BBta_3342 transcriptional regulatory protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein; SPTR: transcriptional regulatory protein; PFAM: Helix-turn-helix; XRE family transcriptional regulator 4282694..4283023 Spirochaeta smaragdinae DSM 11293 9492091 YP_003805645.1 CDS Spirs_3966 NC_014364.1 4283135 4284904 D COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160:IPR011623; KEGG: amt:Amet_4420 sensor diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor transmembrane region; SMART: GGDEF domain containing protein; SPTR: Response regulator receiver protein; TIGRFAM: diguanylate cyclase; PFAM: 7TM diverse intracellular signalling; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; 7TM domain sensor diguanylate cyclase 4283135..4284904 Spirochaeta smaragdinae DSM 11293 9492092 YP_003805646.1 CDS Spirs_3967 NC_014364.1 4284914 4285204 D InterPro IPR020822:IPR002701; KEGG: gva:HMPREF0424_0113 chorismate mutase; PFAM: chorismate mutase, type II; SPTR: chorismate mutase; manually curated; PFAM: chorismate mutase type II; TIGRFAM: monofunctional chorismate mutase, alpha proteobacterial type; chorismate mutase, type II 4284914..4285204 Spirochaeta smaragdinae DSM 11293 9492093 YP_003805647.1 CDS Spirs_3968 NC_014364.1 4285207 4285545 R InterPro IPR013096; KEGG: gem:GM21_0923 cupin 2 conserved barrel domain protein; PFAM: cupin; SPTR: cupin; PFAM: Cupin domain; cupin complement(4285207..4285545) Spirochaeta smaragdinae DSM 11293 9492094 YP_003805648.1 CDS Spirs_3969 NC_014364.1 4285546 4286481 R KEGG: bhy:BHWA1_01280 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4285546..4286481) Spirochaeta smaragdinae DSM 11293 9492095 YP_003805649.1 CDS Spirs_3970 NC_014364.1 4286681 4288750 D COGs: COG3920 Signal transduction histidine kinase; InterProIPR018303:IPR001610:IPR003594:IPR003660:IPR 013767:IPR011495:IPR005467:IPR000700:IPR000014; KEGG: sfu:Sfum_2629 signal transduction histidine kinase; PFAM: histidine kinase dimerisation/phosphoacceptor; histidine kinase HAMP region domain protein; PAS fold domain protein; ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; PAC repeat-containing protein; SPTR: Hypothetical sensory transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; TIGRFAM: PAS domain S-box; signal transduction histidine kinase 4286681..4288750 Spirochaeta smaragdinae DSM 11293 9492096 YP_003805650.1 CDS Spirs_3971 NC_014364.1 4288755 4289927 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: rrs:RoseRS_3454 oxidoreductase domain-containing protein; PFAM: oxidoreductase domain protein; oxidoreductase domain; SPTR: oxidoreductase domain protein; PFAM: oxidoreductase family, C-terminal alpha/beta domain; oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(4288755..4289927) Spirochaeta smaragdinae DSM 11293 9492097 YP_003805651.1 CDS Spirs_3972 NC_014364.1 4290257 4291252 R COGs: COG0078 ornithine carbamoyltransferase; InterPro IPR006130:IPR006132:IPR006131:IPR002292; KEGG: amt:Amet_4608 ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; SPTR: ornithine carbamoyltransferase; TIGRFAM: ornithine carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase; ornithine carbamoyltransferase complement(4290257..4291252) Spirochaeta smaragdinae DSM 11293 9492098 YP_003805652.1 CDS Spirs_3973 NC_014364.1 4291278 4292504 R COGs: COG2235 Arginine deiminase; InterPro IPR003876:IPR003198; KEGG: amt:Amet_4609 arginine deiminase; PFAM: amidinotransferase; PRIAM: Arginine deiminase; SPTR: Arginine deiminase; PFAM: Amidinotransferase; Arginine deiminase complement(4291278..4292504) Spirochaeta smaragdinae DSM 11293 9492099 YP_003805653.1 CDS Spirs_3974 NC_014364.1 4292702 4295362 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR018211:IPR015590:IPR001670:IPR012079; KEGG: tel:tlr0227 bifunctional acetaldehyde-CoA/alcohol dehydrogenase; PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; SPTR: Iron-containing alcohol dehydrogenase; PFAM: aldehyde dehydrogenase family; Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 4292702..4295362 Spirochaeta smaragdinae DSM 11293 9492100 YP_003805654.1 CDS Spirs_3975 NC_014364.1 4295464 4297944 R InterPro IPR013509:IPR000788:IPR013344; KEGG: pjd:Pjdr2_3990 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase large subunit; ribonucleotide reductase large subunit domain protein; SPTR: ribonucleoside-diphosphate reductase; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: ribonucleotide reductase, all-alpha domain; ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent complement(4295464..4297944) Spirochaeta smaragdinae DSM 11293 9492101 YP_003805655.1 CDS Spirs_3976 NC_014364.1 4298100 4298921 R KEGG: tpp:TPASS_0138 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4298100..4298921) Spirochaeta smaragdinae DSM 11293 9492102 YP_003805656.1 CDS Spirs_3977 NC_014364.1 4298930 4299622 R COGs: COG0569 K+ transporters NAD-binding component; InterPro IPR003148:IPR006037; KEGG: tpp:TPASS_0139 hypothetical protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; SPTR: uncharacterized protein; PFAM: TrkA-N domain; TrkA-C domain; TrkA-N domain-containing protein complement(4298930..4299622) Spirochaeta smaragdinae DSM 11293 9492103 YP_003805657.1 CDS Spirs_3978 NC_014364.1 4299645 4301381 R COGs: COG0168 Trk-type K+ transporters membrane components; InterPro IPR003445:IPR004772; KEGG: tde:TDE0312 TrkH family potassium uptake protein; PFAM: cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein, TrkH family; TIGRFAM: potassium uptake protein, TrkH family; PFAM: Cation transporter; TIGRFAM: potassium uptake protein, TrkH family; TrkH family potassium uptake protein complement(4299645..4301381) Spirochaeta smaragdinae DSM 11293 9492104 YP_003805658.1 CDS Spirs_3979 NC_014364.1 4301378 4302451 R COGs: COG4948 L-alanine-DL-glutamate epimerase; InterPro IPR013341:IPR013342:IPR018110; KEGG: dat:HRM2_12000 chloromuconate cycloisomerase-like protein; PFAM: mandelate racemase/muconate lactonizing protein; SPTR: chloromuconate cycloisomerase-like protein; PFAM: mandelate racemase / muconate lactonizing enzyme, C-terminal domain; mandelate racemase / muconate lactonizing enzyme, N-terminal domain; mandelate racemase/muconate lactonizing protein complement(4301378..4302451) Spirochaeta smaragdinae DSM 11293 9492105 YP_003805659.1 CDS Spirs_3980 NC_014364.1 4302448 4303527 R COGs: COG3367 conserved hypothetical protein; InterPro IPR011669; KEGG: pto:PTO0563 hypothetical protein; PFAM: protein of unknown function DUF1611; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1611); hypothetical protein complement(4302448..4303527) Spirochaeta smaragdinae DSM 11293 9492106 YP_003805660.1 CDS Spirs_3981 NC_014364.1 4303673 4303882 D KEGG: rmr:Rmar_2197 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF2892); hypothetical protein 4303673..4303882 Spirochaeta smaragdinae DSM 11293 9492107 YP_003805661.1 CDS Spirs_3982 NC_014364.1 4304054 4304947 R InterPro IPR000182; KEGG: cpc:Cpar_1398 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; GCN5-like N-acetyltransferase complement(4304054..4304947) Spirochaeta smaragdinae DSM 11293 9492108 YP_003805662.1 CDS Spirs_3983 NC_014364.1 4304940 4306250 R COGs: COG1509 lysine 2 3-aminomutase; InterPro IPR007197:IPR003739; KEGG: mbu:Mbur_0274 L-lysine 2,3-aminomutase; PFAM: radical SAM protein; PRIAM: lysine 2,3-aminomutase; SPTR: L-lysine 2,3-aminomutase; TIGRFAM: lysine 2,3-aminomutase YodO family protein; PFAM: lysine-2,3-aminomutase; radical SAM superfamily; TIGRFAM: KamA family protein; lysine 2,3-aminomutase YodO family protein complement(4304940..4306250) Spirochaeta smaragdinae DSM 11293 9492109 YP_003805663.1 CDS Spirs_3984 NC_014364.1 4306376 4308145 R COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR000559:IPR020628; KEGG: det:DET0705 formate--tetrahydrofolate ligase; PFAM: formate-tetrahydrofolate ligase FTHFS; PRIAM: formate--tetrahydrofolate ligase; SPTR: formate--tetrahydrofolate ligase; PFAM: formate--tetrahydrofolate ligase; formate--tetrahydrofolate ligase complement(4306376..4308145) Spirochaeta smaragdinae DSM 11293 9492110 YP_003805664.1 CDS Spirs_3985 NC_014364.1 4308344 4309639 R COGs: COG5026 hexokinase; InterPro IPR001312; KEGG: tpp:TPASS_0505 hexokinase; PFAM: hexokinase; PRIAM: hexokinase; SPTR: uncharacterized protein; PFAM: hexokinase; hexokinase complement(4308344..4309639) Spirochaeta smaragdinae DSM 11293 9492111 YP_003805665.1 CDS Spirs_3986 NC_014364.1 4309639 4309995 R KEGG: pgn:PGN_0779 uracil phosphoribosyltransferase; SPTR: uracil phosphoribosyltransferase; hypothetical protein complement(4309639..4309995) Spirochaeta smaragdinae DSM 11293 9492112 YP_003805666.1 CDS Spirs_3987 NC_014364.1 4309997 4311229 R COGs: COG0475 Kef-type K+ transporters membrane components; InterPro IPR006153; KEGG: cbf:CLI_2824 monovalent cation:proton antiporter-2 (CPA2) family protein; PFAM: sodium/hydrogen exchanger; SPTR: transporter monovalent cation:proton antiporter-2 (CPA2) family; PFAM: Sodium/hydrogen exchanger family; sodium/hydrogen exchanger complement(4309997..4311229) Spirochaeta smaragdinae DSM 11293 9492113 YP_003805667.1 CDS Spirs_3988 NC_014364.1 4311245 4311697 R COGs: COG1762 phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type); InterPro IPR002178; KEGG: cfe:CF0658 phosphotransferase system mannitol/fructose-specific Pts IIA; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; SPTR: uncharacterized protein; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; PTS IIA-like nitrogen-regulatory protein PtsN complement(4311245..4311697) Spirochaeta smaragdinae DSM 11293 9492114 YP_003805668.1 CDS Spirs_3989 NC_014364.1 4311798 4312472 R COGs: COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain; InterPro IPR001789; KEGG: hoh:Hoch_6548 response regulator receiver sensor signal transduction histidine kinase; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Sensor protein; PFAM: Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; response regulator receiver protein complement(4311798..4312472) Spirochaeta smaragdinae DSM 11293 9492115 YP_003805669.1 CDS Spirs_3990 NC_014364.1 4312469 4314571 R COGs: COG5002 Signal transduction histidine kinase; InterProIPR013656:IPR003661:IPR003594:IPR000014:IPR 005467:IPR004358; KEGG: cyt:cce_1138 two-component hybrid sensor and regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; multi-sensor signal transduction histidine kinase complement(4312469..4314571) Spirochaeta smaragdinae DSM 11293 9492116 YP_003805670.1 CDS Spirs_3991 NC_014364.1 4314583 4315743 R COGs: COG0857 BioD-like N-terminal domain of phosphotransacetylase; KEGG: pti:PHATRDRAFT_50625 hypothetical protein; SPTR: Predicted protein; PFAM: DRTGG domain; hypothetical protein complement(4314583..4315743) Spirochaeta smaragdinae DSM 11293 9492117 YP_003805671.1 CDS Spirs_3992 NC_014364.1 4315815 4316951 D COGs: COG0498 threonine synthase; InterPro IPR001926; KEGG: tvo:TVN0071 threonine synthase; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: threonine synthase; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase; pyridoxal-5'-phosphate-dependent protein subunit beta 4315815..4316951 Spirochaeta smaragdinae DSM 11293 9492118 YP_003805672.1 CDS Spirs_3993 NC_014364.1 4317041 4318159 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 4317041..4318159 Spirochaeta smaragdinae DSM 11293 9492119 YP_003805673.1 CDS Spirs_3994 NC_014364.1 4318269 4319606 R COGs: COG0334 glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006097:IPR006096:IPR006095:IPR014362; KEGG: bfs:BF3437 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase ; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: glutamate dehydrogenase (NADP(+)); SPTR: NAD dependent glutamate dehydrogenase 1; PFAM: glutamate/Leucine/phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; glutamate dehydrogenase (NADP(+)) complement(4318269..4319606) Spirochaeta smaragdinae DSM 11293 9492120 YP_003805674.1 CDS Spirs_3995 NC_014364.1 4319817 4322759 D InterPro IPR001789:IPR002192; KEGG: pdi:BDI_3805 phosphoenolpyruvate synthase/pyruvate phosphate dikinase; PFAM: response regulator receiver; pyruvate phosphate dikinase PEP/pyruvate-binding; SPTR: phosphoenolpyruvate synthase/pyruvate phosphate dikinase; PFAM: Response regulator receiver domain; pyruvate phosphate dikinase, PEP/pyruvate binding domain; response regulator receiver protein 4319817..4322759 Spirochaeta smaragdinae DSM 11293 9492121 YP_003805675.1 CDS Spirs_3996 NC_014364.1 4322749 4323951 R COGs: COG0436 aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR004838:IPR001176; KEGG: fjo:Fjoh_2271 aspartate aminotransferase; PFAM: aminotransferase class I and II; SPTR: aspartate aminotransferase; PFAM: Aminotransferase class I and II; class I and II aminotransferase complement(4322749..4323951) Spirochaeta smaragdinae DSM 11293 9492122 YP_003805676.1 CDS Spirs_3997 NC_014364.1 4324080 4325177 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR001789:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: bfs:BF2190 two component system histidine kinase/response regulator fusion protein; PFAM: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SMART: response regulator receiver; histidine kinase A domain protein; ATP-binding region ATPase domain protein; SPTR: Sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; response regulator receiver sensor signal transduction histidine kinase complement(4324080..4325177) Spirochaeta smaragdinae DSM 11293 9492123 YP_003805677.1 CDS Spirs_3998 NC_014364.1 4325204 4325614 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: tnp:Tnap_0250 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator receiver protein; PFAM: Response regulator receiver domain; response regulator receiver protein complement(4325204..4325614) Spirochaeta smaragdinae DSM 11293 9492124 YP_003805678.1 CDS Spirs_3999 NC_014364.1 4325637 4326782 R COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterPro IPR008207; KEGG: ppg:PputGB1_3907 chemotaxis protein CheA; PFAM: Hpt domain protein; SMART: Hpt domain protein; SPTR: Probable chemotaxis sensor histidine kinase protein; PFAM: Hpt domain; chemotaxis protein CheA complement(4325637..4326782) Spirochaeta smaragdinae DSM 11293 9492125 YP_003805679.1 CDS Spirs_4000 NC_014364.1 4326775 4327224 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: pca:Pcar_2015 two component hybrid sensor response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Stand-alone receiver (REC) domain; PFAM: Response regulator receiver domain; response regulator receiver protein complement(4326775..4327224) Spirochaeta smaragdinae DSM 11293 9492126 YP_003805680.1 CDS Spirs_4001 NC_014364.1 4327267 4329297 R KEGG: tde:TDE0585 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4327267..4329297) Spirochaeta smaragdinae DSM 11293 9492127 YP_003805681.1 CDS Spirs_4002 NC_014364.1 4329364 4330053 R COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006145; KEGG: pseudouridylate synthase; PFAM: pseudouridine synthase; SPTR: Pseudouridine synthase; PFAM: RNA pseudouridylate synthase; pseudouridine synthase complement(4329364..4330053) Spirochaeta smaragdinae DSM 11293 9492128 YP_003805682.1 CDS Spirs_4003 NC_014364.1 4330046 4331977 R COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) subunit alpha; InterPro IPR002205; KEGG: tde:TDE2118 DNA topoisomerase IV subunit A; PFAM: DNA gyrase/topoisomerase IV subunit A; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: Topoisomerase IV, subunit alpha, ; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA topoisomerase complement(4330046..4331977) Spirochaeta smaragdinae DSM 11293 9492129 YP_003805683.1 CDS Spirs_4004 NC_014364.1 4331978 4333771 R COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) subunit beta; InterPro IPR003594:IPR013506:IPR001241:IPR000565; KEGG: tde:TDE2245 DNA topoisomerase IV subunit B; PFAM: DNA topoisomerase type IIsubunit alpha B region 2 domain protein; ATP-binding region ATPase domain protein; SMART: DNA topoisomerase II; SPTR: DNA topoisomerase 4 subunit B; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase subunit beta, carboxyl terminus; DNA topoisomerase type IIA subunit B region 2 domain-containing protein complement(4331978..4333771) Spirochaeta smaragdinae DSM 11293 9492130 YP_003805684.1 CDS Spirs_4005 NC_014364.1 4333803 4336244 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR013656:IPR013767:IPR003661:IPR003594:IPR 001789:IPR000014:IPR005467:IPR000700:IPR004358; KEGG: dvl:Dvul_0331 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; PAS fold; TIGRFAM: PAS domain S-box; PAS/PAC sensor hybrid histidine kinase complement(4333803..4336244) Spirochaeta smaragdinae DSM 11293 9492131 YP_003805685.1 CDS Spirs_4006 NC_014364.1 4336420 4337151 D KEGG: sat:SYN_00536 cytoplasmic protein; SPTR: Hypothetical cytosolic protein; PFAM: nucleotidyltransferase domain; hypothetical protein 4336420..4337151 Spirochaeta smaragdinae DSM 11293 9492132 YP_003805686.1 CDS Spirs_4007 NC_014364.1 4337156 4337956 D COGs: COG1512 beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: sat:SYN_00537 beta-propeller domain-containing protein; PFAM: protein of unknown function DUF477; SPTR: beta-propeller domain of methanol dehydrogenase type protein; PFAM: Domain of unknown function (DUF477); hypothetical protein 4337156..4337956 Spirochaeta smaragdinae DSM 11293 9492133 YP_003805687.1 CDS Spirs_4008 NC_014364.1 4337986 4338570 D COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: tex:Teth514_0283 LemA family protein; PFAM: LemA family protein; SPTR: LemA family protein; PFAM: LemA family; LemA family protein 4337986..4338570 Spirochaeta smaragdinae DSM 11293 9492134 YP_003805688.1 CDS Spirs_4010 NC_014364.1 4339131 4339412 D InterPro IPR000504; KEGG: nis:NIS_0278 RNA-binding protein RNP-1; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; SPTR: RNP-1 like RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); RNP-1 like RNA-binding protein 4339131..4339412 Spirochaeta smaragdinae DSM 11293 9492136 YP_003805689.1 CDS Spirs_4011 NC_014364.1 4339729 4342104 R COGs: COG0616 Periplasmic serine protease (ClpP class); InterPro IPR002142:IPR004635; KEGG: mav:MAV_4443 signal peptide peptidase SppA, 67K type; PFAM: peptidase S49; SPTR: acid phosphatase; TIGRFAM: signal peptide peptidase SppA, 36K type; PFAM: peptidase family S49; TIGRFAM: signal peptide peptidase SppA, 36K type; signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type complement(4339729..4342104) Spirochaeta smaragdinae DSM 11293 9492137 YP_003805690.1 CDS Spirs_4012 NC_014364.1 4342101 4344296 R COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089:IPR004090; KEGG: tde:TDE0640 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor complement(4342101..4344296) Spirochaeta smaragdinae DSM 11293 9492138 YP_003805691.1 CDS Spirs_4013 NC_014364.1 4344634 4346019 D COGs: COG1509 lysine 2 3-aminomutase; InterPro IPR000169; KEGG: ote:Oter_0373 radical SAM domain-containing protein; SPTR: radical SAM protein; TIGRFAM: KamA family protein; radical SAM domain-containing protein 4344634..4346019 Spirochaeta smaragdinae DSM 11293 9492139 YP_003805692.1 CDS Spirs_4014 NC_014364.1 4346116 4347324 D COGs: COG0578 glycerol-3-phosphate dehydrogenase; InterPro IPR006076:IPR000447; KEGG: dvl:Dvul_0583 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; SPTR: Anaerobic glycerol-3-phosphate dehydrogenase, subunit A, truncation; PFAM: FAD dependent oxidoreductase; FAD dependent oxidoreductase 4346116..4347324 Spirochaeta smaragdinae DSM 11293 9492140 YP_003805693.1 CDS Spirs_4015 NC_014364.1 4347315 4347965 D COGs: COG0479 succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterProIPR001041:IPR006058:IPR017900:IPR004489:IPR 017896; KEGG: dvm:DvMF_1127 succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; SPTR: succinate dehydrogenase and fumarate reductase iron-sulfur protein; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: 2Fe-2S iron-sulfur cluster binding domain; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; succinate dehydrogenase and fumarate reductase iron-sulfur protein 4347315..4347965 Spirochaeta smaragdinae DSM 11293 9492141 YP_003805694.1 CDS Spirs_4016 NC_014364.1 4348133 4348345 D InterPro IPR005899; KEGG: cja:CJA_2756 oxaloacetate decarboxylase gamma chain; PFAM: sodium pump decarboxylase subunit gamma; SPTR: Oxaloacetate decarboxylase gamma chain; PFAM: Oxaloacetate decarboxylase, gamma chain; TIGRFAM: sodium pump decarboxylases, subunit gamma; sodium pump decarboxylase subunit gamma 4348133..4348345 Spirochaeta smaragdinae DSM 11293 9492142 YP_003805695.1 CDS Spirs_4017 NC_014364.1 4348363 4350165 D COGs: COG5016 pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR000089:IPR001882; KEGG: dsa:Desal_0778 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; pyruvate carboxyltransferase; SPTR: Biotin/lipoyl attachment domain-containing protein; PFAM: HMGL-like; Conserved carboxylase domain; Biotin-requiring enzyme; biotin/lipoyl attachment domain-containing protein 4348363..4350165 Spirochaeta smaragdinae DSM 11293 9492143 YP_003805696.1 CDS Spirs_4018 NC_014364.1 4350184 4351341 D COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase subunit beta; InterPro IPR005661; KEGG: cps:CPS_1050 oxaloacetate decarboxylase subunit beta; PFAM: Na+transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; PRIAM: Oxaloacetate decarboxylase; SPTR: Oxaloacetate decarboxylase, subunit beta; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; sodium ion-translocating decarboxylase subunit beta 4350184..4351341 Spirochaeta smaragdinae DSM 11293 9492144 YP_003805697.1 CDS Spirs_4019 NC_014364.1 4351637 4352644 D KEGG: gsu:GSU1945 fibronectin type III domain-containing protein; SPTR: uncharacterized protein; hypothetical protein 4351637..4352644 Spirochaeta smaragdinae DSM 11293 9492145 YP_003805698.1 CDS Spirs_4020 NC_014364.1 4352805 4353572 D COGs: COG3884 acyl-ACP thioesterase; InterPro IPR002864; KEGG: cth:Cthe_3072 acyl-ACP thioesterase; PFAM: acyl-ACP thioesterase; SPTR: acyl-ACP thioesterase; PFAM: acyl-ACP thioesterase; acyl-ACP thioesterase 4352805..4353572 Spirochaeta smaragdinae DSM 11293 9492146 YP_003805699.1 CDS Spirs_4021 NC_014364.1 4353612 4354667 D COGs: COG1052 lactate dehydrogenase and related dehydrogenase; InterPro IPR006139:IPR006140; KEGG: amu:Amuc_0772 phosphoglycerate mutase 1 family; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; SPTR: phosphoglycerate mutase 1 family; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; D-isomer specific 2-hydroxyacid dehydrogenase 4353612..4354667 Spirochaeta smaragdinae DSM 11293 9492147 YP_003805700.1 CDS Spirs_4022 NC_014364.1 4354762 4356660 R COGs: COG1274 phosphoenolpyruvate carboxykinase (GTP); InterPro IPR008209:IPR018091; KEGG: tga:TGAM_1771 phosphoenolpyruvate carboxykinase [GTP] (PckG); PFAM: phosphoenolpyruvate carboxykinase (GTP); PRIAM: phosphoenolpyruvate carboxykinase (GTP); SPTR: phosphoenolpyruvate carboxykinase [GTP] (PckG); PFAM: phosphoenolpyruvate carboxykinase; phosphoenolpyruvate carboxykinase (GTP) complement(4354762..4356660) Spirochaeta smaragdinae DSM 11293 9492148 YP_003805701.1 CDS Spirs_4023 NC_014364.1 4356819 4357790 D COGs: COG0111 phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140; KEGG: gme:Gmet_0106 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; SPTR: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase 4356819..4357790 Spirochaeta smaragdinae DSM 11293 9492149 YP_003805702.1 CDS Spirs_4024 NC_014364.1 4357793 4359088 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR003594:IPR000595; KEGG: tde:TDE0102 cyclic nucleotide-binding protein; PFAM: cyclic nucleotide-binding; ATP-binding region ATPase domain protein; SMART: cyclic nucleotide-binding; SPTR: Cyclic nucleotide-binding protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Cyclic nucleotide-binding domain; cyclic nucleotide modulated signal transduction histidine kinase complement(4357793..4359088) Spirochaeta smaragdinae DSM 11293 9492150 YP_003805703.1 CDS Spirs_4025 NC_014364.1 4359224 4359319 D hypothetical protein 4359224..4359319 Spirochaeta smaragdinae DSM 11293 9492151 YP_003805704.1 CDS Spirs_4026 NC_014364.1 4359407 4359598 D hypothetical protein 4359407..4359598 Spirochaeta smaragdinae DSM 11293 9492152 YP_003805705.1 CDS Spirs_4027 NC_014364.1 4359642 4360676 R COGs: COG0136 aspartate-semialdehyde dehydrogenase; InterPro IPR000534:IPR012280:IPR005676:IPR012080; KEGG: fpl:Ferp_1128 aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase NAD - binding; semialdehyde dehydrogenase dimerisation region; PRIAM: aspartate-semialdehyde dehydrogenase; SPTR: aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: semialdehyde dehydrogenase, dimerisation domain; semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (non-peptidoglycan organisms); aspartate-semialdehyde dehydrogenase complement(4359642..4360676) Spirochaeta smaragdinae DSM 11293 9492153 YP_003805706.1 CDS Spirs_4028 NC_014364.1 4360838 4361077 D SPTR: 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; hypothetical protein 4360838..4361077 Spirochaeta smaragdinae DSM 11293 9492154 YP_003805707.1 CDS Spirs_4029 NC_014364.1 4361113 4362525 R COGs: COG1463 ABC-type transporter involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: scl:sce7646 ABC-type organic solvent transporter solute-binding periplasmic protein; PFAM: hypothetical protein; SPTR: ABC-type organic solvent transporter solute-binding periplasmic protein, ; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein; hypothetical protein complement(4361113..4362525) Spirochaeta smaragdinae DSM 11293 9492155 YP_003805708.1 CDS Spirs_4030 NC_014364.1 4362510 4363289 R COGs: COG1127 ABC-type transporter involved in resistance to organic solvents ATPase component; InterPro IPR003439:IPR017871:IPR001579:IPR003593; KEGG: sat:SYN_00410 ABC-type transporter, ATP-binding component; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(4362510..4363289) Spirochaeta smaragdinae DSM 11293 9492156 YP_003805709.1 CDS Spirs_4031 NC_014364.1 4363300 4364061 R COGs: COG0767 ABC-type transporter involved in resistance to organic solvents permease; InterPro IPR003453; KEGG: drt:Dret_0676 protein of unknown function DUF140; PFAM: protein of unknown function DUF140; SPTR: uncharacterized protein; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein; hypothetical protein complement(4363300..4364061) Spirochaeta smaragdinae DSM 11293 9492157 YP_003805710.1 CDS Spirs_4033 NC_014364.1 4364464 4366560 D COGs: COG0840 methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089; KEGG: tde:TDE0850 methyl-accepting chemotaxis protein; PFAM: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; Cache domain protein; SMART: chemotaxis sensory transducer; histidine kinase HAMP region domain protein; SPTR: methyl-accepting chemotaxis protein; PFAM: Cache domain; HAMP domain; methyl-accepting chemotaxis protein (MCP) signaling domain; methyl-accepting chemotaxis sensory transducer with Cache sensor 4364464..4366560 Spirochaeta smaragdinae DSM 11293 9492159 YP_003805711.1 CDS Spirs_4034 NC_014364.1 4366600 4366866 R COGs: COG0724 RNA-binding protein (RRM domain); InterPro IPR000504:IPR003954; KEGG: dma:DMR_11610 RNA-binding protein; PFAM: RNP-1 like RNA-binding protein; SMART: RNP-1 like RNA-binding protein; RNA recognition, region 1; SPTR: RNA-binding protein; PFAM: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain); RNP-1 like RNA-binding protein complement(4366600..4366866) Spirochaeta smaragdinae DSM 11293 9492160 YP_003805712.1 CDS Spirs_4035 NC_014364.1 4367264 4367392 R hypothetical protein complement(4367264..4367392) Spirochaeta smaragdinae DSM 11293 9492162 YP_003805713.1 CDS Spirs_4036 NC_014364.1 4367392 4367877 R InterPro IPR002068; KEGG: dde:Dde_2798 small HspC2 heat shock protein; PFAM: heat shock protein Hsp20; SPTR: Small HspC2 heat shock protein; PFAM: Hsp20/alpha crystallin family; heat shock protein Hsp20 complement(4367392..4367877) Spirochaeta smaragdinae DSM 11293 9492163 YP_003805714.1 CDS Spirs_4037 NC_014364.1 4368068 4368883 D COGs: COG1692 conserved hypothetical protein; KEGG: tde:TDE1535 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: conserved hypothetical protein TIGR00282; hypothetical protein 4368068..4368883 Spirochaeta smaragdinae DSM 11293 9492164 YP_003805715.1 CDS Spirs_4038 NC_014364.1 4368880 4369296 D COGs: COG3086 Positive regulator of sigma E activity; InterPro IPR007359; KEGG: ypb:YPTS_3005 SoxR reducing system protein RseC; PFAM: Positive regulator of sigma(E) RseC/MucC; SPTR: Sigma E factor regulatory protein; PFAM: Positive regulator of sigma(E), RseC/MucC; positive regulator of sigma E, RseC/MucC 4368880..4369296 Spirochaeta smaragdinae DSM 11293 9492165 YP_003805716.1 CDS Spirs_4039 NC_014364.1 4369286 4370479 R COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR001789:IPR000673:IPR008248; KEGG: tpp:TPASS_0631 protein-glutamate methylesterase; PFAM: CheB methylesterase; response regulator receiver; PRIAM: protein-glutamate methylesterase; SMART: response regulator receiver; SPTR: Chemotaxis response regulator protein-glutamate methylesterase; PFAM: CheB methylesterase; Response regulator receiver domain; response regulator receiver modulated CheB methylesterase complement(4369286..4370479) Spirochaeta smaragdinae DSM 11293 9492166 YP_003805717.1 CDS Spirs_4041 NC_014364.1 4371212 4372261 R InterPro IPR001584; KEGG: dap:Dacet_2583 integrase catalytic region; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; manually curated; PFAM: Integrase core domain; Integrase catalytic subunit complement(4371212..4372261) Spirochaeta smaragdinae DSM 11293 9492168 YP_003805718.1 CDS Spirs_4042 NC_014364.1 4372285 4372767 R InterPro IPR002514; KEGG: paa:Paes_0650 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase; transposase IS3/IS911 family protein complement(4372285..4372767) Spirochaeta smaragdinae DSM 11293 9492169 YP_003805719.1 CDS Spirs_4043 NC_014364.1 4373057 4373548 D InterPro IPR003729; KEGG: cyh:Cyan8802_1249 protein of unknown function DUF151; PFAM: protein of unknown function DUF151; SPTR: uncharacterized protein; PFAM: Uncharacterised ACR, COG1259; hypothetical protein 4373057..4373548 Spirochaeta smaragdinae DSM 11293 9492170 YP_003805720.1 CDS Spirs_4044 NC_014364.1 4373605 4375221 D COGs: COG0504 CTP synthase (UTP-ammonia lyase); InterPro IPR017456:IPR000991:IPR004468:IPR017926; KEGG: lic:LIC11540 CTP synthetase; PFAM: CTP synthase-like; glutamine amidotransferase class-I; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; PFAM: glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase; CTP synthase 4373605..4375221 Spirochaeta smaragdinae DSM 11293 9492171 YP_003805721.1 CDS Spirs_4045 NC_014364.1 4375199 4375828 D InterPro IPR010664; KEGG: bga:BG0477 hypothetical protein; PFAM: protein of unknown function DUF1239; SPTR: uncharacterized protein; PFAM: protein of unknown function (DUF1239); hypothetical protein 4375199..4375828 Spirochaeta smaragdinae DSM 11293 9492172 YP_003805722.1 CDS Spirs_4046 NC_014364.1 4375818 4376489 D KEGG: tde:TDE0645 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4375818..4376489 Spirochaeta smaragdinae DSM 11293 9492173 YP_003805723.1 CDS Spirs_4047 NC_014364.1 4376486 4377235 D COGs: COG1137 ABC-type (unclassified) transporter ATPase component; InterPro IPR003439:IPR003593; KEGG: tde:TDE0644 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 4376486..4377235 Spirochaeta smaragdinae DSM 11293 9492174 YP_003805724.1 CDS Spirs_4048 NC_014364.1 4377282 4378667 D COGs: COG1508 DNA-directed RNA polymerase specialized sigma subunit sigma54 homolog; InterPro IPR000394:IPR007046:IPR007634; KEGG: lbl:LBL_1670 DNA-directed RNA polymerase sigma-54 subunit; PFAM: sigma-54 DNA-binding domain protein; sigma-54 factor core-binding region; sigma-54 factor; SPTR: DNA-directed RNA polymerase sigma-54 subunit; TIGRFAM: RNA polymerase sigma-54 factor, RpoN; manually curated; PFAM: Sigma-54 factor, activator interacting domain (AID); Sigma-54 factor, core binding domain; Sigma-54, DNA binding domain; TIGRFAM: RNA polymerase sigma-54 factor; RNA polymerase, sigma-54 subunit RpoN 4377282..4378667 Spirochaeta smaragdinae DSM 11293 9492175 YP_003805725.1 CDS Spirs_4049 NC_014364.1 4378730 4379050 D InterPro IPR003489; KEGG: bhr:BH0449 ribosome-associated factor Y; SPTR: ribosome-associated factor Y; TIGRFAM: ribosomal subunit interface protein; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein; ribosomal subunit interface protein 4378730..4379050 Spirochaeta smaragdinae DSM 11293 9492176 YP_003805726.1 CDS Spirs_4050 NC_014364.1 4379057 4380040 D COGs: COG1493 serine kinase of the HPr protein regulates carbohydrate metabolism; InterPro IPR011126:IPR011104:IPR003755; KEGG: tpa:TP0591 HPr kinase/phosphorylase; PFAM: HPr serine kinase domain protein; SPTR: HPr(Ser) kinase/phosphatase; TIGRFAM: HPr(Ser) kinase/phosphatase; PFAM: HPr serine kinase N terminus; HPr serine kinase C-terminal domain; TIGRFAM: Hpr(Ser) kinase/phosphatase; HPr kinase 4379057..4380040 Spirochaeta smaragdinae DSM 11293 9492177 YP_003805727.1 CDS Spirs_4051 NC_014364.1 4380049 4380315 D COGs: COG1925 phosphotransferase system HPr-related protein; InterPro IPR005698:IPR001020:IPR002114:IPR000032; KEGG: tde:TDE1294 phosphocarrier protein HPr; PFAM: phosphoryl transfer system HPr; SPTR: phosphocarrier protein HPr; TIGRFAM: phosphocarrier, HPr family; PFAM: PTS HPr component phosphorylation site; TIGRFAM: phosphotransferase System HPr (HPr) Family; phosphotransferase system, phosphocarrier protein HPr 4380049..4380315 Spirochaeta smaragdinae DSM 11293 9492178 YP_003805728.1 CDS Spirs_4052 NC_014364.1 4380272 4380874 D KEGG: afm:AFUA_8G00350 hypothetical protein; SPTR: ATP-binding protein; hypothetical protein 4380272..4380874 Spirochaeta smaragdinae DSM 11293 9492179 YP_003805729.1 CDS Spirs_4053 NC_014364.1 4380874 4382661 D COGs: COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation; InterProIPR003660:IPR003661:IPR003594:IPR005467:IPR 004358; KEGG: lbf:LBF_1603 sensor histidine kinase of a two component response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SPTR: Sensor protein; PFAM: HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain; integral membrane sensor signal transduction histidine kinase 4380874..4382661 Spirochaeta smaragdinae DSM 11293 9492180 YP_003805730.1 CDS Spirs_4054 NC_014364.1 4382662 4384026 D COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789:IPR002078:IPR002197:IPR003593; KEGG: gem:GM21_0962 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: Response regulator receiver domain; Bacterial regulatory protein, Fis family; Sigma-54 interaction domain; Fis family transcriptional regulator 4382662..4384026 Spirochaeta smaragdinae DSM 11293 9492181 YP_003805731.1 CDS Spirs_4055 NC_014364.1 4384023 4384637 D COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); InterPro IPR006199:IPR019759:IPR006200:IPR006197; KEGG: lbf:LBF_1262 LexA repressor; PFAM: LexA DNA-binding domain protein; peptidase S24/S26A/S26B, conserved region; SPTR: LexA repressor; TIGRFAM: LexA repressor; PFAM: LexA DNA binding domain; peptidase S24-like; TIGRFAM: SOS regulatory protein LexA; LexA family transcriptional repressor 4384023..4384637 Spirochaeta smaragdinae DSM 11293 9492182 YP_003805732.1 CDS Spirs_4056 NC_014364.1 4384637 4385665 D COGs: COG1466 DNA polymerase III subunit delta; InterPro IPR010372:IPR005790; KEGG: tde:TDE0729 hypothetical protein; PFAM: DNA polymerase III delta; SPTR: uncharacterized protein; TIGRFAM: DNA polymerase III, subunit delta; PFAM: DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III subunit delta; DNA polymerase III subunit delta 4384637..4385665 Spirochaeta smaragdinae DSM 11293 9492183 YP_003805733.1 CDS Spirs_4057 NC_014364.1 4385682 4386641 R COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; InterPro IPR015168:IPR001638; KEGG: hor:Hore_14770 NlpA lipoprotein; PFAM: NMT1/THI5 like domain protein; SMART: extracellular solute-binding protein family 3; SPTR: ABC transporter periplasmic substrate-binding protein; PFAM: NMT1/THI5 like; NMT1/THI5 like domain-containing protein complement(4385682..4386641) Spirochaeta smaragdinae DSM 11293 9492184 YP_003805734.1 CDS Spirs_4058 NC_014364.1 4386638 4387249 R COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR003382:IPR004507; KEGG: amt:Amet_4582 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; SPTR: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase complement(4386638..4387249) Spirochaeta smaragdinae DSM 11293 9492185 YP_003805735.1 CDS Spirs_4059 NC_014364.1 4387246 4388145 R COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: swo:Swol_0678 4-hydroxybenzoate polyprenyltransferase, PFAM: UbiA prenyltransferase; SPTR: 4-hydroxybenzoate polyprenyltransferase, ; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; PFAM: UbiA prenyltransferase family; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase; 4-hydroxybenzoate polyprenyltransferase complement(4387246..4388145) Spirochaeta smaragdinae DSM 11293 9492186 YP_003805736.1 CDS Spirs_4060 NC_014364.1 4388124 4389563 R COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: hor:Hore_14820 UbiD family decarboxylase; PFAM: carboxylyase-related protein; SPTR: UbiD family decarboxylase; TIGRFAM: UbiD family decarboxylase; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; UbiD family decarboxylase complement(4388124..4389563) Spirochaeta smaragdinae DSM 11293 9492187 YP_003805737.1 CDS Spirs_4061 NC_014364.1 4389656 4390339 R COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595:IPR012318; KEGG: cdf:CD2170 cNMP-binding regulatory protein; SPTR: Crp/Fnr family transcriptional regulator; Crp/Fnr family transcriptional regulator complement(4389656..4390339) Spirochaeta smaragdinae DSM 11293 9492188 YP_003805738.1 CDS Spirs_4062 NC_014364.1 4390502 4391515 D COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transporters periplasmic components; KEGG: dhd:Dhaf_3902 hypothetical protein; SPTR: uncharacterized protein; PFAM: NMT1/THI5 like; hypothetical protein 4390502..4391515 Spirochaeta smaragdinae DSM 11293 9492189 YP_003805739.1 CDS Spirs_4063 NC_014364.1 4391499 4392221 D COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: dhd:Dhaf_3901 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 4391499..4392221 Spirochaeta smaragdinae DSM 11293 9492190 YP_003805740.1 CDS Spirs_4064 NC_014364.1 4392214 4392909 D COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR003439:IPR003593; KEGG: dhd:Dhaf_3900 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter 4392214..4392909 Spirochaeta smaragdinae DSM 11293 9492191 YP_003805741.1 CDS Spirs_4065 NC_014364.1 4392912 4393574 D InterPro IPR013096; KEGG: cco:CCC13826_0495 5'-nucleotidase SurE; PFAM: cupin; SPTR: Cupin 2 domain-containing protein; PFAM: Cupin domain; cupin 4392912..4393574 Spirochaeta smaragdinae DSM 11293 9492192 YP_003805742.1 CDS Spirs_4066 NC_014364.1 4393667 4394413 D COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: dae:Dtox_2282 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: Taurine ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter 4393667..4394413 Spirochaeta smaragdinae DSM 11293 9492193 YP_003805743.1 CDS Spirs_4067 NC_014364.1 4394410 4395150 D COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transporter permease; InterPro IPR000515; KEGG: drm:Dred_2780 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: ABC superfamily ATP binding cassette transporter permease; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component 4394410..4395150 Spirochaeta smaragdinae DSM 11293 9492194 YP_003805744.1 CDS Spirs_4068 NC_014364.1 4395592 4397397 R COGs: COG0322 Nuclease subunit of the excinuclease complex; InterPro IPR000305:IPR001943:IPR001162:IPR004791; KEGG: hor:Hore_16210 excinuclease ABC, C subunit; PFAM: excinuclease ABC C subunit domain protein; excinuclease ABC C subunit domain protein; UvrB/UvrC protein; SMART: excinuclease ABC C subunit domain protein; SPTR: excinuclease ABC, C subunit; TIGRFAM: excinuclease ABC, C subunit; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit; excinuclease ABC subunit C complement(4395592..4397397) Spirochaeta smaragdinae DSM 11293 9492195 YP_003805745.1 CDS Spirs_4069 NC_014364.1 4397442 4398638 R COGs: COG4214 ABC-type xylose transporter permease component; InterPro IPR001851; KEGG: gtn:GTNG_1799 L-arabinose membrane permease; PFAM: inner-membrane translocator; SPTR: sugar ATP transporter ATPase; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(4397442..4398638) Spirochaeta smaragdinae DSM 11293 9492196 YP_003805746.1 CDS Spirs_4070 NC_014364.1 4398655 4400178 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: gka:GK1909 ABC transporter ATP-binding protein; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter ATP-binding protein; PFAM: ABC transporter; ABC transporter complement(4398655..4400178) Spirochaeta smaragdinae DSM 11293 9492197 YP_003805747.1 CDS Spirs_4071 NC_014364.1 4400251 4401348 R COGs: COG4213 ABC-type xylose transporter periplasmic component; KEGG: msm:MSMEG_1704 ABC transporter; SPTR: ABC transporter; ABC transporter complement(4400251..4401348) Spirochaeta smaragdinae DSM 11293 9492198 YP_003805748.1 CDS Spirs_4072 NC_014364.1 4401486 4402541 R COGs: COG4213 ABC-type xylose transporter periplasmic component; KEGG: gka:GK1881 D-xylose ABC transporter substrate-binding protein; SPTR: D-xylose ABC transporter substrate-binding protein; PFAM: family; TIGRFAM: D-xylose ABC transporter substrate-binding protein; D-xylose ABC transporter substrate-binding protein complement(4401486..4402541) Spirochaeta smaragdinae DSM 11293 9492199 YP_003805749.1 CDS Spirs_4073 NC_014364.1 4402528 4404042 R COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterProIPR001789:IPR000005:IPR018062:IPR018060:IPR 020449; KEGG: cpy:Cphy_1583 AraC family transcriptional regulator; PFAM: response regulator receiver; helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; response regulator receiver; SPTR: Two component AraC family transcriptional regulator; PFAM: Response regulator receiver domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(4402528..4404042) Spirochaeta smaragdinae DSM 11293 9492200 YP_003805750.1 CDS Spirs_4074 NC_014364.1 4404027 4405508 R COGs: COG3275 regulator of cell autolysis; InterPro IPR003660:IPR010559:IPR003594; KEGG: tit:Thit_0243 signal transduction histidine kinase, LytS; PFAM: histidine kinase internal region; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain protein; SPTR: histidine kinase family protein; PFAM: histidine kinase; HAMP domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase LytS complement(4404027..4405508) Spirochaeta smaragdinae DSM 11293 9492201 YP_003805751.1 CDS Spirs_4075 NC_014364.1 4405505 4406464 R COGs: COG1879 ABC-type sugar transporter periplasmic component; KEGG: tte:TTE0286 periplasmic sugar-binding proteins; SPTR: Periplasmic sugar-binding proteins; PFAM: family; sugar ABC transporter periplasmic protein complement(4405505..4406464) Spirochaeta smaragdinae DSM 11293 9492202 YP_003805752.1 CDS Spirs_4076 NC_014364.1 4406612 4408183 D InterPro IPR003961; KEGG: tde:TDE0446 fibronectin type III domain-containing protein; PFAM: Fibronectin type III domain protein; SMART: Fibronectin type III domain protein; SPTR: Fibronectin type III domain protein; PFAM: Fibronectin type III domain; fibronectin type III 4406612..4408183 Spirochaeta smaragdinae DSM 11293 9492203 YP_003805753.1 CDS Spirs_4077 NC_014364.1 4408186 4410648 D COGs: COG5010 Flp pilus assembly protein TadD contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734:IPR013026; KEGG: cyh:Cyan8802_1328 peptidase S1 and S6 chymotrypsin/Hap; PFAM: hypothetical protein; hypothetical protein; SPTR: TPR domain protein; PFAM: Tetratricopeptide repeat; hypothetical protein 4408186..4410648 Spirochaeta smaragdinae DSM 11293 9492204 YP_003805754.1 CDS Spirs_4078 NC_014364.1 4410645 4411526 D COGs: COG1639 signal transduction protein; InterPro IPR013976:IPR003607; KEGG: dps:DP0004 hypothetical protein; PFAM: metal-dependent hydrolase HDOD; SMART: metal-dependent phosphohydrolase HD region; SPTR: metal-dependent phosphohydrolase, HD subdomain; PFAM: HDOD domain; TIGRFAM: uncharacterized domain HDIG; metal dependent phosphohydrolase 4410645..4411526 Spirochaeta smaragdinae DSM 11293 9492205 YP_003805755.1 CDS Spirs_4079 NC_014364.1 4411523 4412446 D COGs: COG1235 metal-dependent hydrolase of the beta-lactamase superfamily I; KEGG: dps:DP0003 hypothetical protein; SPTR: uncharacterized protein; PFAM: metallo-beta-lactamase superfamily; hypothetical protein 4411523..4412446 Spirochaeta smaragdinae DSM 11293 9492206 YP_003805756.1 CDS Spirs_4080 NC_014364.1 4412500 4413216 D COGs: COG2186 transcriptional regulators; InterPro IPR000524; KEGG: fal:FRAAL2830 GntR family transcriptional regulator; PFAM: regulatory protein GntR HTH; SMART: regulatory protein GntR HTH; SPTR: GntR-family transcriptional regulator; PFAM: Bacterial regulatory proteins, gntR family; regulatory protein GntR 4412500..4413216 Spirochaeta smaragdinae DSM 11293 9492207 YP_003805757.1 CDS Spirs_4081 NC_014364.1 4413213 4414547 D COGs: COG1533 DNA repair photolyase; KEGG: dat:HRM2_08590 DNA repair photolyase SplB-like protein; SPTR: DNA repair photolyase SplB-like protein; DNA repair photolyase SplB-like protein 4413213..4414547 Spirochaeta smaragdinae DSM 11293 9492208 YP_003805758.1 CDS Spirs_4082 NC_014364.1 4414728 4414877 D hypothetical protein 4414728..4414877 Spirochaeta smaragdinae DSM 11293 9492210 YP_003805759.1 CDS Spirs_4083 NC_014364.1 4414874 4416034 D COGs: COG1454 alcohol dehydrogenase class IV; InterPro IPR001670:IPR018211; KEGG: chy:CHY_0925 lactaldehyde reductase; PFAM: iron-containing alcohol dehydrogenase; SPTR: alcohol dehydrogenase; PFAM: Iron-containing alcohol dehydrogenase; iron-containing alcohol dehydrogenase 4414874..4416034 Spirochaeta smaragdinae DSM 11293 9492212 YP_003805760.1 CDS Spirs_4084 NC_014364.1 4416035 4416412 R COGs: COG1539 dihydroneopterin aldolase; InterPro IPR006157:IPR006156; KEGG: drm:Dred_0155 dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; SPTR: dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; PFAM: dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain; dihydroneopterin aldolase complement(4416035..4416412) Spirochaeta smaragdinae DSM 11293 9492213 YP_003805761.1 CDS Spirs_4085 NC_014364.1 4416467 4417354 R COGs: COG0657 esterase/lipase; InterPro IPR013094; KEGG: reh:H16_B1249 esterase/lipase; PFAM: alpha/beta hydrolase fold-3 domain protein; SPTR: esterase/lipase; PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold-3 domain-containing protein complement(4416467..4417354) Spirochaeta smaragdinae DSM 11293 9492214 YP_003805762.1 CDS Spirs_4086 NC_014364.1 4417386 4418525 R COGs: COG0530 Ca2+/Na+ antiporter; InterPro IPR004837:IPR004481; KEGG: syn:slr0681 hypothetical protein; PFAM: sodium/calcium exchanger membrane region; SPTR: uncharacterized protein; TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: Sodium/calcium exchanger protein; TIGRFAM: K+-dependent Na+/Ca+ exchanger related-protein; CaCA family Na+/Ca+ antiporter complement(4417386..4418525) Spirochaeta smaragdinae DSM 11293 9492215 YP_003805763.1 CDS Spirs_4088 NC_014364.1 4419038 4419880 R COGs: COG4221 Short-chain alcohol dehydrogenase of unknown specificity; InterPro IPR002198:IPR002347; KEGG: pjd:Pjdr2_1690 short chain dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; SPTR: Short-chain dehydrogenase/reductase SDR; PFAM: short chain dehydrogenase; short-chain dehydrogenase/reductase SDR complement(4419038..4419880) Spirochaeta smaragdinae DSM 11293 9492217 YP_003805764.1 CDS Spirs_4089 NC_014364.1 4419974 4420861 R InterPro IPR001611; KEGG: lmy:LM5923_0305 internalin G; PFAM: leucine-rich repeat protein; SPTR: S4 domain protein; PFAM: Leucine Rich Repeat; leucine-rich repeat protein complement(4419974..4420861) Spirochaeta smaragdinae DSM 11293 9492218 YP_003805765.1 CDS Spirs_4090 NC_014364.1 4420953 4421366 D COGs: COG1186 protein chain release factor B; InterPro IPR000352; KEGG: dba:Dbac_2864 class I peptide chain release factor; PFAM: class I peptide chain release factor; SPTR: class I peptide chain release factor; PFAM: RF-1 domain; class I peptide chain release factor 4420953..4421366 Spirochaeta smaragdinae DSM 11293 9492219 YP_003805766.1 CDS Spirs_4091 NC_014364.1 4421430 4422080 R KEGG: bth:BT_3335 hypothetical protein; SPTR: uncharacterized protein; PFAM: Domain of unknown function (DUF1083); hypothetical protein complement(4421430..4422080) Spirochaeta smaragdinae DSM 11293 9492220 YP_003805767.1 CDS Spirs_4092 NC_014364.1 4422088 4423086 R COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683; KEGG: gym:GYMC10_1295 oxidoreductase domain protein; PFAM: oxidoreductase domain protein; SPTR: oxidoreductase domain protein; PFAM: oxidoreductase family, NAD-binding Rossmann fold; oxidoreductase domain-containing protein complement(4422088..4423086) Spirochaeta smaragdinae DSM 11293 9492221 YP_003805768.1 CDS Spirs_4093 NC_014364.1 4423101 4423931 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: gym:GYMC10_1296 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4423101..4423931) Spirochaeta smaragdinae DSM 11293 9492222 YP_003805769.1 CDS Spirs_4094 NC_014364.1 4423934 4424812 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: gym:GYMC10_1297 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: uncharacterized protein; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4423934..4424812) Spirochaeta smaragdinae DSM 11293 9492223 YP_003805770.1 CDS Spirs_4095 NC_014364.1 4424882 4426201 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: gym:GYMC10_1298 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: uncharacterized protein; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(4424882..4426201) Spirochaeta smaragdinae DSM 11293 9492224 YP_003805771.1 CDS Spirs_4096 NC_014364.1 4426373 4427638 D COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594; KEGG: cbe:Cbei_3866 integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein; SPTR: Two-component system sensor histidine kinase; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; signal transduction histidine kinase 4426373..4427638 Spirochaeta smaragdinae DSM 11293 9492225 YP_003805772.1 CDS Spirs_4097 NC_014364.1 4427616 4428260 D COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: cbl:CLK_3042 transcriptional regulatory protein DegU (protease production enhancerprotein); PFAM: response regulator receiver; regulatory protein LuxR; SMART: response regulator receiver; regulatory protein LuxR; SPTR: transcriptional regulatory protein DegU; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family; LuxR family transcriptional regulator 4427616..4428260 Spirochaeta smaragdinae DSM 11293 9492226 YP_003805773.1 CDS Spirs_4098 NC_014364.1 4428263 4428829 R COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: nth:Nther_2176 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase complement(4428263..4428829) Spirochaeta smaragdinae DSM 11293 9492227 YP_003805774.1 CDS Spirs_4099 NC_014364.1 4428937 4429710 D COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR000838:IPR014284; KEGG: cbb:CLD_3538 sigma-70 family RNA polymerase sigma factor; PFAM: sigma-70 region 2 domain protein; Sigma-70 region 4 type 2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; ECF subfamily RNA polymerase sigma-24 subunit 4428937..4429710 Spirochaeta smaragdinae DSM 11293 9492228 YP_003805775.1 CDS Spirs_4100 NC_014364.1 4429778 4430221 D KEGG: cbf:CLI_1113 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4429778..4430221 Spirochaeta smaragdinae DSM 11293 9492229 YP_003805776.1 CDS Spirs_4101 NC_014364.1 4430218 4431138 R COGs: COG1893 Ketopantoate reductase; InterPro IPR013332:IPR013752:IPR003710; KEGG: alv:Alvin_2715 2-dehydropantoate 2-reductase; PFAM: ketopantoate reductase; PRIAM: 2-dehydropantoate 2-reductase; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase; 2-dehydropantoate 2-reductase complement(4430218..4431138) Spirochaeta smaragdinae DSM 11293 9492230 YP_003805777.1 CDS Spirs_4102 NC_014364.1 4431196 4431366 R hypothetical protein complement(4431196..4431366) Spirochaeta smaragdinae DSM 11293 9492231 YP_003805778.1 CDS Spirs_4103 NC_014364.1 4431475 4432359 D COGs: COG0702 nucleoside-diphosphate-sugar epimerase; InterPro IPR008030; KEGG: pmr:PMI1161 hypothetical protein; PFAM: NmrA family protein; SPTR: uncharacterized protein; PFAM: NmrA-like family; NmrA family protein 4431475..4432359 Spirochaeta smaragdinae DSM 11293 9492232 YP_003805779.1 CDS Spirs_4104 NC_014364.1 4432382 4433287 R KEGG: pgi:PG0160 hypothetical protein; SPTR: Conserved domain protein; PFAM: nucleotidyl transferase; hypothetical protein complement(4432382..4433287) Spirochaeta smaragdinae DSM 11293 9492233 YP_003805780.1 CDS Spirs_4105 NC_014364.1 4433420 4435861 D KEGG: azo:azo3061 GGDEF/EAL/PAS/PAC/GAF-domain-containing protein; SPTR: signal transduction GGDEF domain membrane protein; hypothetical protein 4433420..4435861 Spirochaeta smaragdinae DSM 11293 9492234 YP_003805781.1 CDS Spirs_4106 NC_014364.1 4435876 4436715 R COGs: COG1351 alternative thymidylate synthase; InterPro IPR003669; KEGG: tde:TDE0311 FAD-dependent thymidylate synthase; PFAM: thymidylate synthase complementing protein ThyX; SPTR: Thymidylate synthase thyX; TIGRFAM: thymidylate synthase, flavin-dependent; PFAM: Thymidylate synthase complementing protein; TIGRFAM: thymidylate synthase, flavin-dependent; thymidylate synthase, flavin-dependent complement(4435876..4436715) Spirochaeta smaragdinae DSM 11293 9492235 YP_003805782.1 CDS Spirs_4107 NC_014364.1 4436828 4438108 D KEGG: gym:GYMC10_3761 alcohol acetyltransferase; SPTR: uncharacterized protein; alcohol acetyltransferase 4436828..4438108 Spirochaeta smaragdinae DSM 11293 9492236 YP_003805783.1 CDS Spirs_4108 NC_014364.1 4438113 4438976 D KEGG: str:Sterm_2786 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4438113..4438976 Spirochaeta smaragdinae DSM 11293 9492237 YP_003805784.1 CDS Spirs_4109 NC_014364.1 4438939 4439712 R COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: tde:TDE2720 16S ribosomal RNA methyltransferase RsmE; PFAM: protein of unknown function DUF558; SPTR: uncharacterized protein; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family; hypothetical protein complement(4438939..4439712) Spirochaeta smaragdinae DSM 11293 9492238 YP_003805785.1 CDS Spirs_4110 NC_014364.1 4439804 4441537 D COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR001140:IPR003439:IPR017871:IPR003593:IPR 017940; KEGG: tit:Thit_0781 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter 4439804..4441537 Spirochaeta smaragdinae DSM 11293 9492239 YP_003805786.1 CDS Spirs_4111 NC_014364.1 4441537 4443654 D COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR001140:IPR003439:IPR003593:IPR017940; KEGG: dth:DICTH_0509 ABC-type multidrug/protein/lipid transporter, ATPase component; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: AAA ATPase; SPTR: ABC-type multidrug/protein/lipid transporter, ATPase component; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter 4441537..4443654 Spirochaeta smaragdinae DSM 11293 9492240 YP_003805787.1 CDS Spirs_4112 NC_014364.1 4443743 4444753 D COGs: COG0095 Lipoate-protein ligase A; InterPro IPR004143:IPR019491:IPR004562; KEGG: pcr:Pcryo_0197 lipoyltransferase and lipoate-protein ligase; PFAM: biotin/lipoate A/B protein ligase; Lipoate protein ligase-like; SPTR: Lipoate-protein ligase A; TIGRFAM: lipoyltransferase and lipoate-protein ligase; PFAM: Bacterial lipoate protein ligase C-terminus; Biotin/lipoate A/B protein ligase family; TIGRFAM: lipoyltransferase and lipoate-protein ligase; lipoyltransferase and lipoate-protein ligase 4443743..4444753 Spirochaeta smaragdinae DSM 11293 9492241 YP_003805788.1 CDS Spirs_4114 NC_014364.1 4445175 4446842 D COGs: COG4166 ABC-type oligopeptide transporter periplasmic component; InterPro IPR000914; KEGG: tde:TDE2049 solute-binding family 5 protein; PFAM: extracellular solute-binding protein family 5; SPTR: Bacterial extracellular solute-binding protein, family 5; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle; family 5 extracellular solute-binding protein 4445175..4446842 Spirochaeta smaragdinae DSM 11293 9492243 YP_003805789.1 CDS Spirs_4115 NC_014364.1 4446817 4448385 R COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR003385; KEGG: rca:Rcas_2645 4-alpha-glucanotransferase; PFAM: glycoside hydrolase family 77; PRIAM: 4-alpha-glucanotransferase; SPTR: glycoside hydrolase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; 4-alpha-glucanotransferase complement(4446817..4448385) Spirochaeta smaragdinae DSM 11293 9492244 YP_003805790.1 CDS Spirs_4116 NC_014364.1 4448463 4448978 D COGs: COG1329 transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: tpp:TPASS_0511 transcription factor; PFAM: transcription factor CarD; SPTR: transcription factor (CarD); PFAM: CarD-like/TRCF domain; CarD family transcriptional regulator 4448463..4448978 Spirochaeta smaragdinae DSM 11293 9492245 YP_003805791.1 CDS Spirs_4117 NC_014364.1 4448975 4449676 D COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; InterPro IPR001228:IPR018294; KEGG: tde:TDE2291 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase 4448975..4449676 Spirochaeta smaragdinae DSM 11293 9492246 YP_003805792.1 CDS Spirs_4118 NC_014364.1 4449673 4450173 D COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; InterPro IPR003526:IPR020555; KEGG: sus:acid_1861 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: MECDP-synthase; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: YgbB family; TIGRFAM: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 4449673..4450173 Spirochaeta smaragdinae DSM 11293 9492247 YP_003805793.1 CDS Spirs_4119 NC_014364.1 4450170 4450844 D COGs: COG0177 endoIII-related endonuclease; InterPro IPR003265:IPR003651:IPR004035:IPR004036; KEGG: pmx:PERMA_0607 probable endonuclease III (DNA-(apurinic orapyrimidinic site) lyase); PFAM: HhH-GPD family protein; iron-sulfur cluster loop; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD family protein; SPTR: Probable endonuclease III (DNA-(Apurinic orapyrimidinic site) lyase); PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III; DNA-(apurinic or apyrimidinic site) lyase 4450170..4450844 Spirochaeta smaragdinae DSM 11293 9492248 YP_003805794.1 CDS Spirs_4120 NC_014364.1 4451105 4452547 D COGs: COG0147 anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR019999; KEGG: fsu:Fisuc_0137 anthranilate synthase; PFAM: chorismate binding-like; anthranilate synthase component I domain protein; PRIAM: anthranilate synthase; SPTR: anthranilate synthase component 1; PFAM: anthranilate synthase component I, N terminal region; chorismate binding enzyme; anthranilate synthase 4451105..4452547 Spirochaeta smaragdinae DSM 11293 9492249 YP_003805795.1 CDS Spirs_4121 NC_014364.1 4452544 4454169 D COGs: COG0547 anthranilate phosphoribosyltransferase; InterProIPR000991:IPR017459:IPR000312:IPR006221:IPR 005940:IPR017926:IPR006220:IPR011702:IPR001317; KEGG: fsu:Fisuc_0138 anthranilate phosphoribosyltransferase; PFAM: glycosyl transferase family 3; glutamine amidotransferase class-I; glycosyl transferase, family 3-like; SPTR: anthranilate phosphoribosyltransferase; TIGRFAM: anthranilate phosphoribosyltransferase; glutamine amidotransferase of anthranilate synthase; PFAM: glycosyl transferase family, a/b domain; glutamine amidotransferase class-I; glycosyl transferase family, helical bundle domain; TIGRFAM: glutamine amidotransferase or aminodeoxychorismate synthase; anthranilate phosphoribosyltransferase; anthranilate phosphoribosyltransferase 4452544..4454169 Spirochaeta smaragdinae DSM 11293 9492250 YP_003805796.1 CDS Spirs_4122 NC_014364.1 4454159 4455739 D COGs: COG0134 indole-3-glycerol phosphate synthase; InterPro IPR013798:IPR001240:IPR001468:IPR018208; KEGG: fsu:Fisuc_0176 indole-3-glycerol-phosphate synthase., phosphoribosylanthranilate isomerase; PFAM: indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate isomerase (PRAI); SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: indole-3-glycerol phosphate synthase; N-(5'phosphoribosyl)anthranilate (PRA) isomerase; indole-3-glycerol phosphate synthase 4454159..4455739 Spirochaeta smaragdinae DSM 11293 9492251 YP_003805797.1 CDS Spirs_4123 NC_014364.1 4455736 4456989 D COGs: COG0133 tryptophan synthase beta chain; InterPro IPR001926:IPR006653:IPR006654; KEGG: fsu:Fisuc_0179 tryptophan synthase, beta subunit; PFAM: pyridoxal-5'-phosphate-dependent protein subunit beta; SPTR: tryptophan synthase subunit beta; TIGRFAM: tryptophan synthase, beta subunit; PFAM: pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase subunit beta; tryptophan synthase subunit beta 4455736..4456989 Spirochaeta smaragdinae DSM 11293 9492252 YP_003805798.1 CDS Spirs_4124 NC_014364.1 4456986 4457768 D COGs: COG0159 tryptophan synthase alpha chain; InterPro IPR002028; KEGG: fsu:Fisuc_0180 tryptophan synthase, subunit alpha; PFAM: tryptophan synthase alpha chain; SPTR: tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, subunit alpha; PFAM: tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, subunit alpha; tryptophan synthase subunit alpha 4456986..4457768 Spirochaeta smaragdinae DSM 11293 9492253 YP_003805799.1 CDS Spirs_4125 NC_014364.1 4457893 4458594 R KEGG: tde:TDE1050 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4457893..4458594) Spirochaeta smaragdinae DSM 11293 9492254 YP_003805800.1 CDS Spirs_4126 NC_014364.1 4458655 4460745 R COGs: COG0480 translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 004540:IPR005225; KEGG: tde:TDE1049 elongation factor G; PFAM: protein synthesis factor GTP-binding; elongation factor Tu domain 2 protein; elongation factor G domain IV; elongation factor G domain protein; SPTR: translation elongation factor G; TIGRFAM: translation elongation factor G; small GTP-binding protein; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain; translation elongation factor G complement(4458655..4460745) Spirochaeta smaragdinae DSM 11293 9492255 YP_003805801.1 CDS Spirs_4127 NC_014364.1 4460953 4461756 D COGs: COG1801 conserved hypothetical protein; InterPro IPR002763; KEGG: mta:Moth_0268 hypothetical protein; PFAM: protein of unknown function DUF72; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF72; hypothetical protein 4460953..4461756 Spirochaeta smaragdinae DSM 11293 9492256 YP_003805802.1 CDS Spirs_4128 NC_014364.1 4461716 4462150 D KEGG: pan:PODANSg5041 hypothetical protein; SPTR: Predicted protein; hypothetical protein 4461716..4462150 Spirochaeta smaragdinae DSM 11293 9492257 YP_003805803.1 CDS Spirs_4129 NC_014364.1 4462147 4464750 D InterPro IPR004155; KEGG: ter:Tery_1841 peptidase C14, caspase catalytic subunit P20; PFAM: PBS lyase HEAT domain protein repeat-containing protein; SPTR: peptidase C14, caspase catalytic subunit p20; PFAM: HEAT repeat; PBS lyase HEAT domain-containing protein repeat-containing protein 4462147..4464750 Spirochaeta smaragdinae DSM 11293 9492258 YP_003805804.1 CDS Spirs_4130 NC_014364.1 4464756 4465349 D KEGG: apr:Apre_1054 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4464756..4465349 Spirochaeta smaragdinae DSM 11293 9492259 YP_003805805.1 CDS Spirs_4131 NC_014364.1 4465346 4466074 D KEGG: mka:MK1429 Fe-S oxidoreductase; SPTR: Fe-S oxidoreductase; hypothetical protein 4465346..4466074 Spirochaeta smaragdinae DSM 11293 9492260 YP_003805806.1 CDS Spirs_4132 NC_014364.1 4466041 4468449 R COGs: COG0642 Signal transduction histidine kinase; InterProIPR003661:IPR003594:IPR001789:IPR008207:IPR 000014:IPR005467:IPR000700:IPR004358; KEGG: dal:Dalk_3917 multi-sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; response regulator receiver; Hpt domain protein; SPTR: Sensor protein; TIGRFAM: PAS sensor protein; PFAM: histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; His Kinase A (phosphoacceptor) domain; Hpt domain; TIGRFAM: PAS domain S-box; multi-sensor hybrid histidine kinase complement(4466041..4468449) Spirochaeta smaragdinae DSM 11293 9492261 YP_003805807.1 CDS Spirs_4133 NC_014364.1 4468458 4469729 R COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tde:TDE2501 response regulator; PFAM: response regulator receiver; SMART: response regulator receiver; SPTR: Response regulator; PFAM: Response regulator receiver domain; response regulator receiver protein complement(4468458..4469729) Spirochaeta smaragdinae DSM 11293 9492262 YP_003805808.1 CDS Spirs_4134 NC_014364.1 4469865 4470356 R COGs: COG1839 conserved hypothetical protein; InterPro IPR007153; KEGG: ppd:Ppro_2837 hypothetical protein; PFAM: protein of unknown function DUF355; SPTR: uncharacterized protein; PFAM: adenosine specific kinase; hypothetical protein complement(4469865..4470356) Spirochaeta smaragdinae DSM 11293 9492263 YP_003805809.1 CDS Spirs_4135 NC_014364.1 4470356 4472077 R COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterPro IPR005147:IPR004531; KEGG: tde:TDE1927 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase B5; PRIAM: phenylalanine--tRNA ligase; SPTR: Phenylalanyl-tRNA synthetase subunit beta; TIGRFAM: phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase B5 domain; TIGRFAM: phenylalanyl-tRNA synthetase subunit beta; phenylalanyl-tRNA synthetase subunit beta complement(4470356..4472077) Spirochaeta smaragdinae DSM 11293 9492264 YP_003805810.1 CDS Spirs_4136 NC_014364.1 4472080 4473621 R COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR002319:IPR004529:IPR006195; KEGG: tde:TDE0109 phenylalanyl-tRNA synthetase subunit alpha; PFAM: phenylalanyl-tRNA synthetase class IIc; SPTR: Phenylalanyl-tRNA synthetase, subunit alpha; TIGRFAM: phenylalanyl-tRNA synthetase, subunit alpha; PFAM: tRNA synthetases class II core domain (F); TIGRFAM: phenylalanyl-tRNA synthetase, subunit alpha; phenylalanyl-tRNA synthetase subunit alpha complement(4472080..4473621) Spirochaeta smaragdinae DSM 11293 9492265 YP_003805811.1 CDS Spirs_4137 NC_014364.1 4473720 4474994 R KEGG: chl:Chy400_0110 Xaa-Pro aminopeptidase family enzyme; SPTR: Xaa-Pro aminopeptidase family enzyme; PFAM: metallopeptidase family M24; Xaa-Pro aminopeptidase family enzyme complement(4473720..4474994) Spirochaeta smaragdinae DSM 11293 9492266 YP_003805812.1 CDS Spirs_4138 NC_014364.1 4475036 4476352 D COGs: COG0402 cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: drt:Dret_0482 amidohydrolase; PFAM: amidohydrolase; SPTR: Amidohydrolase; PFAM: Amidohydrolase family; amidohydrolase 4475036..4476352 Spirochaeta smaragdinae DSM 11293 9492267 YP_003805813.1 CDS Spirs_4139 NC_014364.1 4476362 4477186 R COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845:IPR018099:IPR011268:IPR011270; KEGG: bbe:BBR47_23830 purine nucleoside phosphorylase I; PFAM: purine or other phosphorylase family 1; SPTR: Purine nucleoside phosphorylase I; TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase family; PFAM: phosphorylase superfamily; TIGRFAM: purine nucleoside phosphorylase I, inosine and guanosine-specific; inosine guanosine and xanthosine phosphorylase family; purine nucleoside phosphorylase I, inosine and guanosine-specific complement(4476362..4477186) Spirochaeta smaragdinae DSM 11293 9492268 YP_003805814.1 CDS Spirs_4140 NC_014364.1 4477256 4478314 R COGs: COG1744 Uncharacterized ABC-type transporter periplasmic component/surface lipoprotein; InterPro IPR003760; KEGG: rxy:Rxyl_0155 basic membrane lipoprotein; PFAM: basic membrane lipoprotein; SPTR: Basic membrane lipoprotein; PFAM: Basic membrane protein; basic membrane lipoprotein complement(4477256..4478314) Spirochaeta smaragdinae DSM 11293 9492269 YP_003805815.1 CDS Spirs_4141 NC_014364.1 4478392 4479339 R COGs: COG1079 ABC-type transporter permease component; InterPro IPR001851; KEGG: hor:Hore_08800 inner-membrane translocator; PFAM: inner-membrane translocator; SPTR: Inner-membrane translocator; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(4478392..4479339) Spirochaeta smaragdinae DSM 11293 9492270 YP_003805816.1 CDS Spirs_4142 NC_014364.1 4479344 4480603 R COGs: COG4603 ABC-type uncharacterized transporter permease; InterPro IPR001851; KEGG: tte:TTE0459 uncharacterized ABC-type transporter, permease; PFAM: inner-membrane translocator; SPTR: amino acid or sugar ABC transporter, permease; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(4479344..4480603) Spirochaeta smaragdinae DSM 11293 9492271 YP_003805817.1 CDS Spirs_4143 NC_014364.1 4480608 4482137 R COGs: COG3845 ABC-type uncharacterized transporters ATPase components; InterPro IPR003439:IPR017871:IPR003593; KEGG: tme:Tmel_0017 ABC transporter; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter; PFAM: ABC transporter; ABC transporter complement(4480608..4482137) Spirochaeta smaragdinae DSM 11293 9492272 YP_003805818.1 CDS Spirs_4144 NC_014364.1 4482352 4483833 D COGs: COG1785 alkaline phosphatase; InterPro IPR001952:IPR018299; KEGG: drt:Dret_2292 alkaline phosphatase; PFAM: alkaline phosphatase; SMART: alkaline phosphatase; SPTR: alkaline phosphatase; PFAM: alkaline phosphatase; alkaline phosphatase 4482352..4483833 Spirochaeta smaragdinae DSM 11293 9492273 YP_003805819.1 CDS Spirs_4145 NC_014364.1 4484064 4485218 D COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: cts:Ctha_1960 YibE/F family protein; PFAM: YibE/F family protein; SPTR: YibE/F family protein; PFAM: YibE/F-like protein; YibE/F family protein 4484064..4485218 Spirochaeta smaragdinae DSM 11293 9492274 YP_003805820.1 CDS Spirs_4146 NC_014364.1 4485200 4487011 R COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR000644:IPR000160; KEGG: dae:Dtox_1949 diguanylate cyclase/phosphodiesterase; PFAM: EAL domain protein; CBS domain containing protein; GGDEF domain containing protein; SMART: EAL domain protein; GGDEF domain containing protein; SPTR: Diguanylate cyclase/phosphodiesterase; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase/phosphodiesterase complement(4485200..4487011) Spirochaeta smaragdinae DSM 11293 9492275 YP_003805821.1 CDS Spirs_4147 NC_014364.1 4487071 4488786 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterProIPR001140:IPR003439:IPR017871:IPR003593:IPR 017940; KEGG: cpy:Cphy_0337 ABC transporter; PFAM: ABC transporter related; ABC transporter transmembrane region; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(4487071..4488786) Spirochaeta smaragdinae DSM 11293 9492276 YP_003805822.1 CDS Spirs_4148 NC_014364.1 4488875 4491373 R COGs: COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein; InterPro IPR006665; KEGG: tde:TDE2028 OmpA family protein; SPTR: OmpA family protein; PFAM: OmpA family; hypothetical protein complement(4488875..4491373) Spirochaeta smaragdinae DSM 11293 9492277 YP_003805823.1 CDS Spirs_4149 NC_014364.1 4491462 4492118 R COGs: COG0274 deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: sth:STH565 deoxyribose-phosphate aldolase; PFAM: deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: deoxyribose-phosphate aldolase; SPTR: deoxyribose-phosphate aldolase; TIGRFAM: deoxyribose-phosphate aldolase; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase; deoxyribose-phosphate aldolase complement(4491462..4492118) Spirochaeta smaragdinae DSM 11293 9492278 YP_003805824.1 CDS Spirs_4150 NC_014364.1 4492119 4493435 R COGs: COG0213 thymidine phosphorylase; InterProIPR017459:IPR000312:IPR013102:IPR017872:IPR 018090:IPR000053; KEGG: drm:Dred_1101 pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; glycosyl transferase, family 3-like; Pyrimidine nucleoside phosphorylase domain; PRIAM: Pyrimidine-nucleoside phosphorylase; SPTR: thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: Pyrimidine nucleoside phosphorylase C-terminal domain; glycosyl transferase family, a/b domain; glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase; pyrimidine-nucleoside phosphorylase complement(4492119..4493435) Spirochaeta smaragdinae DSM 11293 9492279 YP_003805825.1 CDS Spirs_4151 NC_014364.1 4493916 4495034 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 4493916..4495034 Spirochaeta smaragdinae DSM 11293 9492280 YP_003805826.1 CDS Spirs_4153 NC_014364.1 4495311 4496099 D COGs: COG0596 hydrolase or acyltransferase (alpha/beta hydrolase superfamily); InterPro IPR000073; KEGG: bxe:Bxe_B1693 hydrolase; PFAM: alpha/beta hydrolase fold; SPTR: hydrolase; PFAM: alpha/beta hydrolase fold; alpha/beta hydrolase fold protein 4495311..4496099 Spirochaeta smaragdinae DSM 11293 9492282 YP_003805827.1 CDS Spirs_4154 NC_014364.1 4496263 4496748 D KEGG: apo:Arcpr_1208 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4496263..4496748 Spirochaeta smaragdinae DSM 11293 9492283 YP_003805828.1 CDS Spirs_4155 NC_014364.1 4497271 4497843 D COGs: COG4430 conserved hypothetical protein; KEGG: ana:alr0739 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4497271..4497843 Spirochaeta smaragdinae DSM 11293 9492284 YP_003805829.1 CDS Spirs_4156 NC_014364.1 4497932 4498342 D KEGG: cbb:CLD_2991 hypothetical protein; SPTR: uncharacterized protein; PFAM: polyketide cyclase / dehydrase and lipid transport; hypothetical protein 4497932..4498342 Spirochaeta smaragdinae DSM 11293 9492285 YP_003805830.1 CDS Spirs_4158 NC_014364.1 4499074 4499619 D COGs: COG1670 acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: bce:BC4359 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: ribosomal-protein-alanine acetyltransferase; GCN5-like N-acetyltransferase 4499074..4499619 Spirochaeta smaragdinae DSM 11293 9492287 YP_003805831.1 CDS Spirs_4159 NC_014364.1 4499794 4500351 D InterPro IPR000182; KEGG: dsy:DSY0022 hypothetical protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4499794..4500351 Spirochaeta smaragdinae DSM 11293 9492288 YP_003805832.1 CDS Spirs_4160 NC_014364.1 4500355 4500636 D KEGG: abb:ABBFA_000507 peroxisomal trans-2-enoyl-CoA reductase; SPTR: oxidoreductase short-chain dehydrogenase/reductase family; hypothetical protein 4500355..4500636 Spirochaeta smaragdinae DSM 11293 9492289 YP_003805833.1 CDS Spirs_4161 NC_014364.1 4500650 4501042 D InterPro IPR004360; KEGG: cbt:CLH_2446 glyoxalase family protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; glyoxalase/bleomycin resistance protein/dioxygenase 4500650..4501042 Spirochaeta smaragdinae DSM 11293 9492290 YP_003805834.1 CDS Spirs_4162 NC_014364.1 4501185 4501604 D InterPro IPR004360; KEGG: cbf:CLI_0887 glyoxalase family protein; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase family protein; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; glyoxalase/bleomycin resistance protein/dioxygenase 4501185..4501604 Spirochaeta smaragdinae DSM 11293 9492291 YP_003805835.1 CDS Spirs_4163 NC_014364.1 4502008 4502265 D KEGG: lme:LEUM_1144 acetyltransferase; SPTR: acetyltransferase, GNAT family; hypothetical protein 4502008..4502265 Spirochaeta smaragdinae DSM 11293 9492292 YP_003805836.1 CDS Spirs_4164 NC_014364.1 4502467 4502673 D KEGG: lbf:LBF_2178 hypothetical protein; SPTR: uncharacterized protein; MazE family transcriptional regulator 4502467..4502673 Spirochaeta smaragdinae DSM 11293 9492293 YP_003805837.1 CDS Spirs_4165 NC_014364.1 4502675 4503025 D COGs: COG3654 Prophage maintenance system killer protein; InterPro IPR003812:IPR006440; KEGG: swo:Swol_2275 death-on-curing protein; PFAM: filamentation induced by cAMP protein Fic; SPTR: Death-on-curing family protein; TIGRFAM: death-on-curing family protein; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein; death-on-curing family protein 4502675..4503025 Spirochaeta smaragdinae DSM 11293 9492294 YP_003805838.1 CDS Spirs_4166 NC_014364.1 4503187 4503441 D COGs: COG2929 conserved hypothetical protein; InterPro IPR007460; KEGG: dol:Dole_0658 hypothetical protein; PFAM: protein of unknown function DUF497; SPTR: uncharacterized protein; manually curated; PFAM: protein of unknown function (DUF497); hypothetical protein 4503187..4503441 Spirochaeta smaragdinae DSM 11293 9492295 YP_003805839.1 CDS Spirs_4167 NC_014364.1 4503446 4503661 D KEGG: fsu:Fisuc_0795 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4503446..4503661 Spirochaeta smaragdinae DSM 11293 9492296 YP_003805840.1 CDS Spirs_4169 NC_014364.1 4504305 4505066 D COGs: COG0491 Zn-dependent hydrolase including glyoxylase; KEGG: ppd:Ppro_2620 beta-lactamase; SPTR: beta-lactamase; PFAM: metallo-beta-lactamase superfamily; beta-lactamase 4504305..4505066 Spirochaeta smaragdinae DSM 11293 9492298 YP_003805841.1 CDS Spirs_4170 NC_014364.1 4505347 4507689 R COGs: COG1882 pyruvate-formate lyase; InterPro IPR004184:IPR001150:IPR010098; KEGG: pca:Pcar_1397 glycerol dehydratase; PFAM: pyruvate formate-lyase PFL; formate C-acetyltransferase glycine radical; PRIAM: formate C-acetyltransferase; SPTR: glycerol dehydratase; TIGRFAM: pyruvate formate-lyase; PFAM: glycine radical; pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1; pyruvate formate-lyase; pyruvate formate-lyase complement(4505347..4507689) Spirochaeta smaragdinae DSM 11293 9492299 YP_003805842.1 CDS Spirs_4171 NC_014364.1 4507734 4508657 R COGs: COG1180 pyruvate-formate lyase-activating enzyme; InterProIPR007197:IPR001450:IPR017900:IPR001989:IPR 012839:IPR017896:IPR011352; KEGG: dde:Dde_3281 radical-activating enzyme; PFAM: radical SAM protein; 4Fe-4S ferredoxin iron-sulfur binding domain protein; PRIAM: [formate-C-acetyltransferase]-activating enzyme; SPTR: radical-activating enzyme; TIGRFAM: glycyl-radical enzyme activating protein family; PFAM: 4Fe-4S binding domain; radical SAM superfamily; TIGRFAM: glycyl-radical enzyme activating protein family; glycyl-radical enzyme activating protein family complement(4507734..4508657) Spirochaeta smaragdinae DSM 11293 9492300 YP_003805843.1 CDS Spirs_4173 NC_014364.1 4510393 4510887 R COGs: COG3090 TRAP-type C4-dicarboxylate transporter small permease; InterPro IPR007387; KEGG: hypothetical TRAP-type C4-dicarboxylate transporter, small permease; PFAM: tripartite ATP-independent periplasmic transporter DctQ component; SPTR: uncharacterized protein; PFAM: tripartite ATP-independent periplasmic transporters, DctQ component; tripartite ATP-independent periplasmic transporter DctQ component complement(4510393..4510887) Spirochaeta smaragdinae DSM 11293 9492302 YP_003805844.1 CDS Spirs_4174 NC_014364.1 4510905 4511909 R COGs: COG1638 TRAP-type C4-dicarboxylate transporter periplasmic component; InterPro IPR018389:IPR004682; KEGG: amt:Amet_1288 TRAP dicarboxylate transporter DctP subunit; PFAM: extracellular solute-binding protein, family 7; SPTR: C4-dicarboxylate transporter C4-dicarboxylate-binding protein, ; TIGRFAM: TRAP dicarboxylate transporter DctP subunit; PFAM: Bacterial extracellular solute-binding protein, family 7; TIGRFAM: tripartite ATP-independent periplasmic transporter solute receptor, DctP family; TRAP dicarboxylate transporter subunit DctP complement(4510905..4511909) Spirochaeta smaragdinae DSM 11293 9492303 YP_003805845.1 CDS Spirs_4175 NC_014364.1 4511991 4513004 R COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891:IPR012425:IPR017629; KEGG: dhd:Dhaf_1245 4-hydroxy-2-oxovalerate aldolase; PFAM: pyruvate carboxyltransferase; DmpG communication domain protein; SPTR: 4-hydroxy-2-oxovalerate aldolase; TIGRFAM: 4-hydroxy-2-oxovalerate aldolase; PFAM: DmpG-like communication domain; HMGL-like; TIGRFAM: 4-hydroxy-2-oxovalerate aldolase; 4-hydroxy-2-oxovalerate aldolase complement(4511991..4513004) Spirochaeta smaragdinae DSM 11293 9492304 YP_003805846.1 CDS Spirs_4176 NC_014364.1 4513026 4513931 R COGs: COG4569 acetaldehyde dehydrogenase (acetylating); InterPro IPR000534:IPR015426:IPR003361; KEGG: dhd:Dhaf_1244 acetaldehyde dehydrogenase (acetylating); PFAM: acetaldehyde dehydrogenase ; semialdehyde dehydrogenase NAD - binding; PRIAM: acetaldehyde dehydrogenase (acetylating); SPTR: acetaldehyde dehydrogenase; TIGRFAM: acetaldehyde dehydrogenase (acetylating); PFAM: semialdehyde dehydrogenase, NAD binding domain; Prokaryotic acetaldehyde dehydrogenase, dimerisation; TIGRFAM: acetaldehyde dehydrogenase (acetylating); acetaldehyde dehydrogenase complement(4513026..4513931) Spirochaeta smaragdinae DSM 11293 9492305 YP_003805847.1 CDS Spirs_4177 NC_014364.1 4514262 4514720 D KEGG: tde:TDE0356 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4514262..4514720 Spirochaeta smaragdinae DSM 11293 9492306 YP_003805848.1 CDS Spirs_4178 NC_014364.1 4514838 4515998 D COGs: COG3835 Sugar diacid utilization regulator; InterPro IPR008599; KEGG: sfr:Sfri_2640 transcriptional regulator, CdaR; PFAM: sugar diacid recognition domain protein; SPTR: uncharacterized protein; PFAM: sugar diacid recognition; transcriptional regulator, CdaR 4514838..4515998 Spirochaeta smaragdinae DSM 11293 9492307 YP_003805849.1 CDS Spirs_4179 NC_014364.1 4516327 4516653 D COGs: COG0599 gamma-carboxymuconolactone decarboxylase subunit; InterPro IPR003779; KEGG: bvu:BVU_2208 hypothetical protein; PFAM: carboxymuconolactone decarboxylase; SPTR: carboxymuconolactone decarboxylase family protein; PFAM: carboxymuconolactone decarboxylase family; carboxymuconolactone decarboxylase 4516327..4516653 Spirochaeta smaragdinae DSM 11293 9492308 YP_003805850.1 CDS Spirs_4180 NC_014364.1 4516733 4517167 D COGs: COG1917 conserved hypothetical protein contains double-stranded beta-helix domain; InterPro IPR013096; KEGG: mmp:MMP0486 hypothetical protein; PFAM: cupin; SPTR: uncharacterized protein; PFAM: Cupin domain; cupin 4516733..4517167 Spirochaeta smaragdinae DSM 11293 9492309 YP_003805851.1 CDS Spirs_4181 NC_014364.1 4517181 4518047 D COGs: COG0656 Aldo/keto reductase related to diketogulonate reductase; InterPro IPR001395:IPR018170:IPR020471; KEGG: glo:Glov_1440 aldo/keto reductase; PFAM: aldo/keto reductase; SPTR: aldose reductase; PFAM: Aldo/keto reductase family; aldo/keto reductase 4517181..4518047 Spirochaeta smaragdinae DSM 11293 9492310 YP_003805852.1 CDS Spirs_4182 NC_014364.1 4518214 4518726 D InterPro IPR000182; KEGG: dhd:Dhaf_2363 prolyl aminopeptidase; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4518214..4518726 Spirochaeta smaragdinae DSM 11293 9492311 YP_003805853.1 CDS Spirs_4183 NC_014364.1 4518790 4519227 D InterPro IPR000182; KEGG: mba:Mbar_A1998 acetyltransferase (GNAT) family protein; PFAM: GCN5-related N-acetyltransferase; SPTR: uncharacterized protein; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4518790..4519227 Spirochaeta smaragdinae DSM 11293 9492312 YP_003805854.1 CDS Spirs_4184 NC_014364.1 4519227 4520384 D COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: bur:Bcep18194_B2673 major facilitator transporter; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator family protein; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 4519227..4520384 Spirochaeta smaragdinae DSM 11293 9492313 YP_003805855.1 CDS Spirs_4185 NC_014364.1 4520463 4521122 D InterPro IPR001647:IPR019793; KEGG: ckr:CKR_2241 hypothetical protein; PFAM: regulatory protein TetR; SPTR: transcriptional regulator, TetR family; PFAM: Bacterial regulatory proteins, tetR family; TetR family transcriptional regulator 4520463..4521122 Spirochaeta smaragdinae DSM 11293 9492314 YP_003805856.1 CDS Spirs_4186 NC_014364.1 4521195 4522334 D KEGG: gvi:gll2718 hypothetical protein; SPTR: Gll2718 protein; PFAM: acyltransferase family; hypothetical protein 4521195..4522334 Spirochaeta smaragdinae DSM 11293 9492315 YP_003805857.1 CDS Spirs_4187 NC_014364.1 4522409 4524703 R COGs: COG3533 conserved hypothetical protein; InterPro IPR011081:IPR012878; KEGG: cpi:Cpin_4617 protein of unknown function DUF1680; PFAM: protein of unknown function DUF1680; Ig domain protein; SPTR: Secreted protein; PFAM: glycosyl hydrolase of unknown function (DUF1680); hypothetical protein complement(4522409..4524703) Spirochaeta smaragdinae DSM 11293 9492316 YP_003805858.1 CDS Spirs_4188 NC_014364.1 4524963 4525859 D COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR000005:IPR018062:IPR018060; KEGG: gwc:GWCH70_0692 transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator; PFAM: AraC-like ligand binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 4524963..4525859 Spirochaeta smaragdinae DSM 11293 9492317 YP_003805859.1 CDS Spirs_4189 NC_014364.1 4526089 4526937 D COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018062:IPR018060:IPR000182; KEGG: cce:Ccel_1051 AraC family transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: uncharacterized protein; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator 4526089..4526937 Spirochaeta smaragdinae DSM 11293 9492318 YP_003805860.1 CDS Spirs_4190 NC_014364.1 4526948 4528309 D COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: cdf:CD3361 multidrug efflux protein; PFAM: multi antimicrobial extrusion protein MatE; SPTR: uncharacterized protein; PFAM: MatE; TIGRFAM: efflux protein, MATE family; multi antimicrobial extrusion protein MatE 4526948..4528309 Spirochaeta smaragdinae DSM 11293 9492319 YP_003805861.1 CDS Spirs_4191 NC_014364.1 4528401 4529465 R COGs: COG1609 transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cpy:Cphy_0590 LacI family transcription regulator; PFAM: periplasmic binding protein/LacI transcriptional regulator; regulatory protein LacI; SMART: regulatory protein LacI; SPTR: transcriptional regulator, LacI family; PFAM: Bacterial regulatory proteins, lacI family; family; LacI family transcriptional regulator complement(4528401..4529465) Spirochaeta smaragdinae DSM 11293 9492320 YP_003805862.1 CDS Spirs_4192 NC_014364.1 4529475 4531427 R COGs: COG3533 conserved hypothetical protein; InterPro IPR012878; KEGG: cpy:Cphy_0591 hypothetical protein; PFAM: protein of unknown function DUF1680; SPTR: cytoplasmic protein; PFAM: glycosyl hydrolase of unknown function (DUF1680); hypothetical protein complement(4529475..4531427) Spirochaeta smaragdinae DSM 11293 9492321 YP_003805863.1 CDS Spirs_4193 NC_014364.1 4531427 4532260 R COGs: COG0395 ABC-type sugar transporter permease component; InterPro IPR000515; KEGG: cce:Ccel_3244 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4531427..4532260) Spirochaeta smaragdinae DSM 11293 9492322 YP_003805864.1 CDS Spirs_4194 NC_014364.1 4532257 4533123 R COGs: COG1175 ABC-type sugar transporters permease components; InterPro IPR000515; KEGG: gym:GYMC10_0455 binding-protein-dependent transporters inner membrane component; PFAM: binding-protein-dependent transporters inner membrane component; SPTR: Binding-protein-dependent transporters inner membrane component; PFAM: Binding-protein-dependent transporter inner membrane component; binding-protein-dependent transporters inner membrane component complement(4532257..4533123) Spirochaeta smaragdinae DSM 11293 9492323 YP_003805865.1 CDS Spirs_4195 NC_014364.1 4533226 4534506 R COGs: COG1653 ABC-type sugar transporter periplasmic component; InterPro IPR006059; KEGG: cce:Ccel_3246 extracellular solute-binding protein family 1; PFAM: extracellular solute-binding protein family 1; SPTR: extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding protein; sugar ABC transporter periplasmic protein complement(4533226..4534506) Spirochaeta smaragdinae DSM 11293 9492324 YP_003805866.1 CDS Spirs_4196 NC_014364.1 4534503 4536572 R KEGG: cce:Ccel_1261 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4534503..4536572) Spirochaeta smaragdinae DSM 11293 9492325 YP_003805867.1 CDS Spirs_4198 NC_014364.1 4538001 4538387 R COGs: COG1733 transcriptional regulator protein; InterPro IPR002577; KEGG: shi:Shel_25590 predicted transcriptional regulator; PFAM: helix-turn-helix HxlR type; SPTR: Predicted transcriptional regulator; PFAM: HxlR-like helix-turn-helix; HxlR family transcriptional regulator complement(4538001..4538387) Spirochaeta smaragdinae DSM 11293 9492327 YP_003805868.1 CDS Spirs_4199 NC_014364.1 4538643 4539821 D COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: dap:Dacet_2634 major facilitator superfamily MFS_1; PFAM: major facilitator superfamily MFS_1; SPTR: Major facilitator superfamily MFS_1; PFAM: Major Facilitator Superfamily; major facilitator superfamily protein 4538643..4539821 Spirochaeta smaragdinae DSM 11293 9492328 YP_003805869.1 CDS Spirs_4201 NC_014364.1 4540405 4540770 R InterPro IPR004360; KEGG: cbe:Cbei_2157 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; glyoxalase/bleomycin resistance protein/dioxygenase complement(4540405..4540770) Spirochaeta smaragdinae DSM 11293 9492330 YP_003805870.1 CDS Spirs_4202 NC_014364.1 4540854 4541033 D KEGG: dsy:DSY2840 transposase; SPTR: uncharacterized protein; transposase 4540854..4541033 Spirochaeta smaragdinae DSM 11293 9492331 YP_003805871.1 CDS Spirs_4203 NC_014364.1 4541035 4541517 D InterPro IPR000182; KEGG: gwc:GWCH70_0864 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4541035..4541517 Spirochaeta smaragdinae DSM 11293 9492332 YP_003805872.1 CDS Spirs_4204 NC_014364.1 4541548 4542315 D KEGG: amt:Amet_3352 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4541548..4542315 Spirochaeta smaragdinae DSM 11293 9492333 YP_003805873.1 CDS Spirs_4205 NC_014364.1 4542495 4543058 R COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347; KEGG: lbr:LVIS_0443 sugar phosphate isomerase; PFAM: sugar isomerase (SIS); PRIAM: 6-phospho-3-hexuloisomerase; SPTR: uncharacterized protein; PFAM: SIS domain; TIGRFAM: 6-phospho 3-hexuloisomerase; 6-phospho-3-hexuloisomerase complement(4542495..4543058) Spirochaeta smaragdinae DSM 11293 9492334 YP_003805874.1 CDS Spirs_4206 NC_014364.1 4543080 4544105 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: dsh:Dshi_0528 ribose/xylose/arabinose/galactoside ABC-type transporter protein; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(4543080..4544105) Spirochaeta smaragdinae DSM 11293 9492335 YP_003805875.1 CDS Spirs_4207 NC_014364.1 4544117 4545130 R COGs: COG1172 ribose/xylose/arabinose/galactoside ABC-type transporters permeases; InterPro IPR001851; KEGG: yen:YE2753 branched-chain amino acid transporter, permease component; PFAM: inner-membrane translocator; SPTR: uncharacterized protein; PFAM: Branched-chain amino acid transporter / permease component; inner-membrane translocator complement(4544117..4545130) Spirochaeta smaragdinae DSM 11293 9492336 YP_003805876.1 CDS Spirs_4208 NC_014364.1 4545114 4546643 R COGs: COG1129 ABC-type sugar transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: nca:Noca_3319 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: uncharacterized protein; PFAM: ABC transporter; ABC transporter complement(4545114..4546643) Spirochaeta smaragdinae DSM 11293 9492337 YP_003805877.1 CDS Spirs_4209 NC_014364.1 4546719 4547723 R COGs: COG1879 ABC-type sugar transporter periplasmic component; InterPro IPR001761; KEGG: dsh:Dshi_0531 ribose/xylose/arabinose/galactoside ABC-type transporter protein; PFAM: periplasmic binding protein/LacI transcriptional regulator; SPTR: uncharacterized protein; PFAM: family; sugar ABC transporter periplasmic protein complement(4546719..4547723) Spirochaeta smaragdinae DSM 11293 9492338 YP_003805878.1 CDS Spirs_4210 NC_014364.1 4547899 4548684 R COGs: COG1349 transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036:IPR018356; KEGG: cbk:CLL_A0733 deoxyribose operon repressor; PFAM: regulatory protein DeoR; SMART: regulatory protein DeoR; SPTR: deoxyribose operon repressor; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain; DeoR family transcriptional regulator complement(4547899..4548684) Spirochaeta smaragdinae DSM 11293 9492339 YP_003805879.1 CDS Spirs_4211 NC_014364.1 4548723 4550180 R COGs: COG1070 Sugar (pentulose and hexulose) kinase; InterPro IPR018484:IPR018485:IPR018483; KEGG: nml:Namu_3323 carbohydrate kinase FGGY; PFAM: carbohydrate kinase, FGGY-like; SPTR: carbohydrate kinase FGGY; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; carbohydrate kinase FGGY complement(4548723..4550180) Spirochaeta smaragdinae DSM 11293 9492340 YP_003805880.1 CDS Spirs_4212 NC_014364.1 4550323 4550850 D COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: bcm:Bcenmc03_4955 aminotransferase class IV; PFAM: formylmethionine deformylase; SPTR: Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase; formylmethionine deformylase 4550323..4550850 Spirochaeta smaragdinae DSM 11293 9492341 YP_003805881.1 CDS Spirs_4213 NC_014364.1 4551088 4551996 R COGs: COG0384 epimerase PhzC/PhzF homolog; InterPro IPR003719; KEGG: mla:Mlab_0381 hypothetical protein; PFAM: Phenazine biosynthesis PhzC/PhzF protein; SPTR: Phenazine biosynthesis protein PhzF family; TIGRFAM: phenazine biosynthesis protein PhzF family; PFAM: Phenazine biosynthesis-like protein; TIGRFAM: phenazine biosynthesis protein PhzF family; phenazine biosynthesis protein PhzF family complement(4551088..4551996) Spirochaeta smaragdinae DSM 11293 9492342 YP_003805882.1 CDS Spirs_4214 NC_014364.1 4552026 4552715 R COGs: COG1600 Uncharacterized Fe-S protein; InterPro IPR017896; KEGG: bth:BT_2346 iron-sulfur cluster-binding protein; SPTR: uncharacterized protein; iron-sulfur cluster-binding protein complement(4552026..4552715) Spirochaeta smaragdinae DSM 11293 9492343 YP_003805883.1 CDS Spirs_4215 NC_014364.1 4552828 4553619 D InterPro IPR002934; KEGG: cbe:Cbei_2024 DNA polymerase subunit beta; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase, beta domain protein region; PFAM: nucleotidyltransferase domain; DNA polymerase beta domain-containing protein region 4552828..4553619 Spirochaeta smaragdinae DSM 11293 9492344 YP_003805884.1 CDS Spirs_4216 NC_014364.1 4553616 4554140 D COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: drm:Dred_1591 peptide deformylase; PFAM: formylmethionine deformylase; PRIAM: peptide deformylase; SPTR: peptide deformylase; TIGRFAM: peptide deformylase; PFAM: polypeptide deformylase; TIGRFAM: peptide deformylase; peptide deformylase 4553616..4554140 Spirochaeta smaragdinae DSM 11293 9492345 YP_003805885.1 CDS Spirs_4217 NC_014364.1 4554182 4555054 D KEGG: acp:A2cp1_1904 methyltransferase type 11; SPTR: methyltransferase type 11; hypothetical protein 4554182..4555054 Spirochaeta smaragdinae DSM 11293 9492346 YP_003805886.1 CDS Spirs_4218 NC_014364.1 4555323 4555937 D COGs: COG1896 hydrolase of HD superfamily; InterPro IPR006674:IPR003607; KEGG: tde:TDE0276 HD domain-containing protein; PFAM: metal-dependent phosphohydrolase HD sub domain; SMART: metal-dependent phosphohydrolase HD region; SPTR: HD domain protein; PFAM: HD domain; metal dependent phosphohydrolase 4555323..4555937 Spirochaeta smaragdinae DSM 11293 9492347 YP_003805887.1 CDS Spirs_4219 NC_014364.1 4555940 4556389 R COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: tro:trd_0514 conserved hypothetical protein TIGR00149; PFAM: protein of unknown function UPF0047; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: conserved hypothetical protein TIGR00149; hypothetical protein complement(4555940..4556389) Spirochaeta smaragdinae DSM 11293 9492348 YP_003805888.1 CDS Spirs_4220 NC_014364.1 4556429 4557511 R COGs: COG0180 tryptophanyl-tRNA synthetase; InterPro IPR002305:IPR001412:IPR002306; KEGG: ppd:Ppro_0579 tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib; PRIAM: tryptophan--tRNA ligase; SPTR: tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase complement(4556429..4557511) Spirochaeta smaragdinae DSM 11293 9492349 YP_003805889.1 CDS Spirs_4221 NC_014364.1 4557705 4558199 D InterPro IPR000182; KEGG: mmx:MmarC6_0403 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; SPTR: GCN5-related N-acetyltransferase; PFAM: acetyltransferase (GNAT) family; GCN5-like N-acetyltransferase 4557705..4558199 Spirochaeta smaragdinae DSM 11293 9492350 YP_003805890.1 CDS Spirs_4222 NC_014364.1 4558301 4558768 D COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: mem:Memar_1254 hypothetical protein; PFAM: protein of unknown function UPF0066; SPTR: uncharacterized protein; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: conserved hypothetical protein TIGR00104; hypothetical protein 4558301..4558768 Spirochaeta smaragdinae DSM 11293 9492351 YP_003805891.1 CDS Spirs_4223 NC_014364.1 4558760 4559638 R COGs: COG2207 AraC-type DNA-binding domain-containing protein; InterPro IPR000005:IPR018060; KEGG: bbe:BBR47_50660 probable transcriptional regulator; PFAM: helix-turn-helix- domain containing protein AraC type; SMART: Helix-turn-helix, AraC domain; SPTR: transcriptional regulator AraC family; PFAM: Bacterial transcription activator, effector binding domain; Bacterial regulatory helix-turn-helix proteins, AraC family; AraC family transcriptional regulator complement(4558760..4559638) Spirochaeta smaragdinae DSM 11293 9492352 YP_003805892.1 CDS Spirs_4224 NC_014364.1 4560165 4561361 R COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: dsa:Desal_0928 diguanylate cyclase with extracellular sensor; PFAM: GGDEF domain containing protein; SMART: GGDEF domain containing protein; SPTR: Diguanylate cyclase; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain; diguanylate cyclase complement(4560165..4561361) Spirochaeta smaragdinae DSM 11293 9492353 YP_003805893.1 CDS Spirs_4225 NC_014364.1 4561442 4562866 R KEGG: tde:TDE0688 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4561442..4562866) Spirochaeta smaragdinae DSM 11293 9492354 YP_003805894.1 CDS Spirs_4226 NC_014364.1 4563379 4565193 R KEGG: krh:KRH_13610 protein-export membrane protein SecF; SPTR: uncharacterized protein; hypothetical protein complement(4563379..4565193) Spirochaeta smaragdinae DSM 11293 9492355 YP_003805895.1 CDS Spirs_4227 NC_014364.1 4565215 4565949 R COGs: COG1213 sugar nucleotidyltransferase; InterPro IPR001228; KEGG: bmq:BMQ_0786 2-aminoethylphosphonate aminotransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: nucleotidyl transferase; PFAM: nucleotidyl transferase; 4-diphosphocytidyl-2C-methyl-D-erythritol synthase complement(4565215..4565949) Spirochaeta smaragdinae DSM 11293 9492356 YP_003805896.1 CDS Spirs_4228 NC_014364.1 4565960 4567060 R COGs: COG0075 serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192:IPR017688; KEGG: noc:Noc_1315 aminotransferase, class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class-V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; PFAM: Aminotransferase class-V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; 2-aminoethylphosphonate aminotransferase complement(4565960..4567060) Spirochaeta smaragdinae DSM 11293 9492357 YP_003805897.1 CDS Spirs_4229 NC_014364.1 4567089 4568234 R COGs: COG4032 thiamine-pyrophosphate-binding protein; InterPro IPR011766:IPR017684; KEGG: bmj:BMULJ_04038 thiamine pyrophosphate-requiring 3-phosphonopyruvate decarboxylase; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; SPTR: phosphonopyruvate decarboxylase; TIGRFAM: phosphonopyruvate decarboxylase; PFAM: thiamine pyrophosphate enzyme, N-terminal TPP binding domain; thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase; phosphonopyruvate decarboxylase complement(4567089..4568234) Spirochaeta smaragdinae DSM 11293 9492358 YP_003805898.1 CDS Spirs_4230 NC_014364.1 4568250 4569872 R COGs: COG2513 PEP phosphonomutase; InterPro IPR012698; KEGG: rme:Rmet_1808 2,3-dimethylmalate lyase; SPTR: phosphoenolpyruvate phosphomutase; TIGRFAM: phosphoenolpyruvate phosphomutase; TIGRFAM: phosphoenolpyruvate phosphomutase; phosphoenolpyruvate phosphomutase complement(4568250..4569872) Spirochaeta smaragdinae DSM 11293 9492359 YP_003805899.1 CDS Spirs_4231 NC_014364.1 4569950 4571365 R COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017475; KEGG: cth:Cthe_1349 undecaprenyl-phosphate galactose phosphotransferase; PFAM: sugar transferase; PRIAM: undecaprenyl-phosphate galactose phosphotransferase; SPTR: undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase complement(4569950..4571365) Spirochaeta smaragdinae DSM 11293 9492360 YP_003805900.1 CDS Spirs_4232 NC_014364.1 4571377 4572285 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: syp:SYNPCC7002_A1423 glycosyl transferase group 2 family protein; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase, group 2 family domain protein; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4571377..4572285) Spirochaeta smaragdinae DSM 11293 9492361 YP_003805901.1 CDS Spirs_4233 NC_014364.1 4572278 4573816 R KEGG: dde:Dde_3315 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4572278..4573816) Spirochaeta smaragdinae DSM 11293 9492362 YP_003805902.1 CDS Spirs_4234 NC_014364.1 4573773 4574198 R InterPro IPR007267; KEGG: psl:Psta_3554 GtrA family protein; PFAM: GtrA family protein; SPTR: uncharacterized protein; PFAM: GtrA-like protein; GtrA family protein complement(4573773..4574198) Spirochaeta smaragdinae DSM 11293 9492363 YP_003805903.1 CDS Spirs_4235 NC_014364.1 4574217 4575851 R KEGG: fno:Fnod_1051 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4574217..4575851) Spirochaeta smaragdinae DSM 11293 9492364 YP_003805904.1 CDS Spirs_4236 NC_014364.1 4575911 4577020 R COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: sbc:SbBS512_E1201 WbwZ; PFAM: glycosyl transferase group 1; SPTR: WbwZ; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase complement(4575911..4577020) Spirochaeta smaragdinae DSM 11293 9492365 YP_003805905.1 CDS Spirs_4237 NC_014364.1 4577021 4578427 R COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017473:IPR017475; KEGG: lic:LIC11459 UDP-glucosyltransferase; PFAM: sugar transferase; PRIAM: undecaprenyl-phosphate galactose phosphotransferase; SPTR: colanic biosynthesis UDP-glucose lipid carrier transferase; TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; TIGRFAM: undecaprenyl-phosphate glucose phosphotransferase; exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; undecaprenyl-phosphate glucose phosphotransferase complement(4577021..4578427) Spirochaeta smaragdinae DSM 11293 9492366 YP_003805906.1 CDS Spirs_4238 NC_014364.1 4578408 4579136 R InterPro IPR000462; KEGG: tcu:Tcur_4106 CDP-alcohol phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: uncharacterized protein; PFAM: CDP-alcohol phosphatidyltransferase; CDP-alcohol phosphatidyltransferase complement(4578408..4579136) Spirochaeta smaragdinae DSM 11293 9492367 YP_003805907.1 CDS Spirs_4239 NC_014364.1 4579142 4580221 R KEGG: rde:RD1_B0051 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4579142..4580221) Spirochaeta smaragdinae DSM 11293 9492368 YP_003805908.1 CDS Spirs_4240 NC_014364.1 4580290 4581411 D COGs: COG0438 glycosyltransferase; InterPro IPR001296:IPR005479; KEGG: sti:Sthe_0904 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glycosyl transferase group 1; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase 4580290..4581411 Spirochaeta smaragdinae DSM 11293 9492369 YP_003805909.1 CDS Spirs_4241 NC_014364.1 4581401 4582546 R COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: mrd:Mrad2831_2711 glycosyl transferase group 1; PFAM: glycosyl transferase group 1; SPTR: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase complement(4581401..4582546) Spirochaeta smaragdinae DSM 11293 9492370 YP_003805910.1 CDS Spirs_4242 NC_014364.1 4582533 4583510 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: gur:Gura_3057 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase, family 2; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4582533..4583510) Spirochaeta smaragdinae DSM 11293 9492371 YP_003805911.1 CDS Spirs_4243 NC_014364.1 4583500 4584810 R InterPro IPR002797; KEGG: sme:SM_b21244 membrane protein, polysaccharide transporter; PFAM: polysaccharide biosynthesis protein; SPTR: polysaccharide biosynthesis protein; PFAM: polysaccharide biosynthesis protein; polysaccharide biosynthesis protein complement(4583500..4584810) Spirochaeta smaragdinae DSM 11293 9492372 YP_003805912.1 CDS Spirs_4244 NC_014364.1 4584821 4586227 R KEGG: rmr:Rmar_0898 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4584821..4586227) Spirochaeta smaragdinae DSM 11293 9492373 YP_003805913.1 CDS Spirs_4245 NC_014364.1 4586247 4587128 R COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: pcu:pc0125 dTDP-4-keto-L-rhamnose reductase, (TDP-rhamnose synthetase), RfbD; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase; dTDP-4-dehydrorhamnose reductase complement(4586247..4587128) Spirochaeta smaragdinae DSM 11293 9492374 YP_003805914.1 CDS Spirs_4246 NC_014364.1 4587125 4587682 R COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: tal:Thal_1464 dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 35-epimerase related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; dTDP-4-dehydrorhamnose 3,5-epimerase complement(4587125..4587682) Spirochaeta smaragdinae DSM 11293 9492375 YP_003805915.1 CDS Spirs_4247 NC_014364.1 4587696 4588451 R KEGG: cts:Ctha_2069 glycosyltransferase; SPTR: glycosyl transferase; PFAM: protein of unknown function (DUF616); glycosyltransferase complement(4587696..4588451) Spirochaeta smaragdinae DSM 11293 9492376 YP_003805916.1 CDS Spirs_4248 NC_014364.1 4588488 4589498 R COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR008089; KEGG: ilo:IL0564 nucleoside-diphosphate-sugar epimerase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: nucleoside-diphosphate-sugar epimerase; manually curated; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase complement(4588488..4589498) Spirochaeta smaragdinae DSM 11293 9492377 YP_003805917.1 CDS Spirs_4249 NC_014364.1 4589495 4590310 R KEGG: xbo:XBJ1_2692 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4589495..4590310) Spirochaeta smaragdinae DSM 11293 9492378 YP_003805918.1 CDS Spirs_4250 NC_014364.1 4590367 4592115 R KEGG: sdy:SDY_0454 potassium efflux protein KefA; SPTR: uncharacterized protein; hypothetical protein complement(4590367..4592115) Spirochaeta smaragdinae DSM 11293 9492379 YP_003805919.1 CDS Spirs_4251 NC_014364.1 4592106 4593206 R KEGG: ppu:PP_3167 benzoate transporter; SPTR: uncharacterized protein; hypothetical protein complement(4592106..4593206) Spirochaeta smaragdinae DSM 11293 9492380 YP_003805920.1 CDS Spirs_4252 NC_014364.1 4593343 4594485 R COGs: COG0438 glycosyltransferase; InterPro IPR001296; KEGG: bpt:Bpet4027 glycosyltransferase; PFAM: glycosyl transferase group 1; SPTR: glycosyltranferase; PFAM: glycosyl transferases group 1; group 1 glycosyl transferase complement(4593343..4594485) Spirochaeta smaragdinae DSM 11293 9492381 YP_003805921.1 CDS Spirs_4253 NC_014364.1 4594482 4595555 R KEGG: hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4594482..4595555) Spirochaeta smaragdinae DSM 11293 9492382 YP_003805922.1 CDS Spirs_4254 NC_014364.1 4595552 4596274 R InterPro IPR003447; KEGG: wsu:WS0049 hypothetical protein; SPTR: uncharacterized protein; PFAM: FemAB family; hypothetical protein complement(4595552..4596274) Spirochaeta smaragdinae DSM 11293 9492383 YP_003805923.1 CDS Spirs_4255 NC_014364.1 4596271 4597023 R KEGG: wsu:WS0048 hypothetical protein; SPTR: uncharacterized protein; PFAM: Uncharacterized protein conserved in bacteria (DUF2334); hypothetical protein complement(4596271..4597023) Spirochaeta smaragdinae DSM 11293 9492384 YP_003805924.1 CDS Spirs_4256 NC_014364.1 4597013 4597990 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: hha:Hhal_0798 glycosyl transferase family protein; PFAM: glycosyl transferase family 2; SPTR: glycosyl transferase, family 2; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4597013..4597990) Spirochaeta smaragdinae DSM 11293 9492385 YP_003805925.1 CDS Spirs_4257 NC_014364.1 4597993 4598913 R KEGG: hsa:2524 fucosyltransferase 2 (secretor status included); SPTR: uncharacterized protein; PFAM: glycosyl transferase family 11; hypothetical protein complement(4597993..4598913) Spirochaeta smaragdinae DSM 11293 9492386 YP_003805926.1 CDS Spirs_4258 NC_014364.1 4598917 4600245 R COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: cvi:CV_4129 udpglucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: Similar to UDP-glucose/GDP-mannose dehydrogenase family; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; nucleotide sugar dehydrogenase complement(4598917..4600245) Spirochaeta smaragdinae DSM 11293 9492387 YP_003805927.1 CDS Spirs_4259 NC_014364.1 4600247 4601461 R COGs: COG0438 glycosyltransferase; KEGG: mpl:Mpal_2186 glycosyl transferase group 1; SPTR: glycosyl transferase group 1; group 1 glycosyl transferase complement(4600247..4601461) Spirochaeta smaragdinae DSM 11293 9492388 YP_003805928.1 CDS Spirs_4260 NC_014364.1 4601431 4602180 R COGs: COG0463 glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: mma:MM_0653 glycosyltransferase involved in cell wall biogenesis; PFAM: glycosyl transferase family 2; SPTR: glycosyltransferase involved in cell wall biogenesis; PFAM: glycosyl transferase family 2; family 2 glycosyl transferase complement(4601431..4602180) Spirochaeta smaragdinae DSM 11293 9492389 YP_003805929.1 CDS Spirs_4261 NC_014364.1 4602461 4603126 R COGs: COG0110 acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: cyn:Cyan7425_4944 hexapeptide repeat-containing protein acetyltransferase; SPTR: O-acetyltransferase; acetyltransferase (isoleucine patch superfamily) complement(4602461..4603126) Spirochaeta smaragdinae DSM 11293 9492390 YP_003805930.1 CDS Spirs_4262 NC_014364.1 4603119 4604021 R KEGG: cyn:Cyan7425_4943 hypothetical protein; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF115; hypothetical protein complement(4603119..4604021) Spirochaeta smaragdinae DSM 11293 9492391 YP_003805931.1 CDS Spirs_4263 NC_014364.1 4604009 4604875 R COGs: COG2089 Sialic acid synthase; InterPro IPR013132; KEGG: pca:Pcar_1277 sialic acid synthase; PFAM: N-acetylneuraminic acid synthase domain; PRIAM: N-acetylneuraminate synthase; SPTR: N-acetylneuraminate synthase; PFAM: NeuB family; N-acetylneuraminate synthase complement(4604009..4604875) Spirochaeta smaragdinae DSM 11293 9492392 YP_003805932.1 CDS Spirs_4264 NC_014364.1 4604865 4606040 R COGs: COG1083 CMP-N-acetylneuraminic acid synthetase; InterPro IPR003329:IPR005834:IPR010023:IPR006549; KEGG: mac:MA3766 acylneuraminate cytidylyltransferase; PFAM: acylneuraminate cytidylyltransferase; haloacid dehalogenase; SPTR: acylneuraminate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA; PFAM: Cytidylyltransferase; haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; HAD-superfamily hydrolase, subfamily IIIA; 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family complement(4604865..4606040) Spirochaeta smaragdinae DSM 11293 9492393 YP_003805933.1 CDS Spirs_4265 NC_014364.1 4606187 4607458 R COGs: COG1134 ABC-type polysaccharide/polyol phosphate transporter ATPase component; InterPro IPR003439:IPR017871:IPR003593; KEGG: mhu:Mhun_3088 ABC transporter related; PFAM: ABC transporter; SMART: ATPase AAA; SPTR: ABC transporter related; PFAM: ABC transporter; ABC transporter complement(4606187..4607458) Spirochaeta smaragdinae DSM 11293 9492394 YP_003805934.1 CDS Spirs_4266 NC_014364.1 4607460 4608329 R COGs: COG1682 ABC-type polysaccharide/polyol phosphate export systems permease; InterPro IPR013525:IPR000412; KEGG: sat:SYN_02655 ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; SPTR: ABC-type polysaccharide/polyol phosphate export systems, permease; PFAM: ABC transporter; ABC transporter complement(4607460..4608329) Spirochaeta smaragdinae DSM 11293 9492395 YP_003805935.1 CDS Spirs_4267 NC_014364.1 4608360 4610180 R COGs: COG1132 ABC-type multidrug transporter ATPase and permeases; InterPro IPR003439:IPR017871:IPR003593:IPR017940; KEGG: srm:SRM_01195 ABC transporter ATP-binding/permease; PFAM: ABC transporter; SMART: AAA ATPase; SPTR: ABC transporter; PFAM: ABC transporter transmembrane region; ABC transporter; ABC transporter complement(4608360..4610180) Spirochaeta smaragdinae DSM 11293 9492396 YP_003805936.1 CDS Spirs_4268 NC_014364.1 4610177 4611121 R COGs: COG0451 nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: mba:Mbar_A0035 GDP-fucose synthetase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: GDP-fucose synthetase; PFAM: NAD dependent epimerase/dehydratase family; NAD-dependent epimerase/dehydratase complement(4610177..4611121) Spirochaeta smaragdinae DSM 11293 9492397 YP_003805937.1 CDS Spirs_4269 NC_014364.1 4611114 4612199 R COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509:IPR002198:IPR006368; KEGG: drm:Dred_3135 GDP-mannose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: GDP-mannose 4,6-dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase; GDP-mannose 4,6-dehydratase complement(4611114..4612199) Spirochaeta smaragdinae DSM 11293 9492398 YP_003805938.1 CDS Spirs_4271 NC_014364.1 4612900 4613172 R KEGG: vei:Veis_2845 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4612900..4613172) Spirochaeta smaragdinae DSM 11293 9492400 YP_003805939.1 CDS Spirs_4272 NC_014364.1 4613246 4613470 R InterPro IPR012933; KEGG: cpb:Cphamn1_1951 YcfA family protein; PFAM: YcfA family protein; SPTR: YcfA family protein; PFAM: YcfA-like protein; YcfA family protein complement(4613246..4613470) Spirochaeta smaragdinae DSM 11293 9492401 YP_003805940.1 CDS Spirs_4273 NC_014364.1 4613470 4613709 R InterPro IPR005357; KEGG: mpl:Mpal_1357 hypothetical protein; PFAM: protein of unknown function UPF0150; SPTR: uncharacterized protein; hypothetical protein complement(4613470..4613709) Spirochaeta smaragdinae DSM 11293 9492402 YP_003805941.1 CDS Spirs_4274 NC_014364.1 4613887 4615209 R COGs: COG1004 UDP-glucose 6-dehydrogenase; InterPro IPR001732:IPR014026:IPR014027:IPR017476; KEGG: bwe:BcerKBAB4_5066 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose 6-dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase; nucleotide sugar dehydrogenase complement(4613887..4615209) Spirochaeta smaragdinae DSM 11293 9492403 YP_003805942.1 CDS Spirs_4275 NC_014364.1 4615273 4615692 R COGs: COG2445 conserved hypothetical protein; InterPro IPR008201; KEGG: bcz:pE33L466_0270 hypothetical protein; PFAM: protein of unknown function DUF86; SPTR: uncharacterized protein; PFAM: protein of unknown function DUF86; hypothetical protein complement(4615273..4615692) Spirochaeta smaragdinae DSM 11293 9492404 YP_003805943.1 CDS Spirs_4276 NC_014364.1 4615673 4616077 R InterPro IPR002934; KEGG: pph:Ppha_1397 DNA polymerase beta domain protein region; PFAM: DNA polymerase beta domain protein region; SPTR: DNA polymerase beta domain protein region; PFAM: nucleotidyltransferase domain; DNA polymerase beta domain-containing protein region complement(4615673..4616077) Spirochaeta smaragdinae DSM 11293 9492405 YP_003805944.1 CDS Spirs_4277 NC_014364.1 4616074 4616634 R InterPro IPR000835; KEGG: pmo:Pmob_1291 regulatory protein MarR; PFAM: regulatory protein MarR; SPTR: Regulatory protein MarR; PFAM: MarR family; MarR family transcriptional regulator complement(4616074..4616634) Spirochaeta smaragdinae DSM 11293 9492406 YP_003805945.1 CDS Spirs_4278 NC_014364.1 4616665 4617231 R COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR000836:IPR005904; KEGG: apa:APP7_0722 hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase; hypoxanthine phosphoribosyltransferase complement(4616665..4617231) Spirochaeta smaragdinae DSM 11293 9492407 YP_003805946.1 CDS Spirs_4279 NC_014364.1 4617554 4618549 D COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611:IPR002173; KEGG: gvi:glr0791 sugar kinase; PFAM: PfkB domain protein; SPTR: Sugar kinase, ribokinase; PFAM: pfkB family carbohydrate kinase; PfkB domain-containing protein 4617554..4618549 Spirochaeta smaragdinae DSM 11293 9492408 YP_003805947.1 CDS Spirs_4280 NC_014364.1 4618551 4619900 R COGs: COG3920 Signal transduction histidine kinase; InterProIPR001789:IPR013656:IPR011495:IPR003594:IPR 000014; KEGG: lbl:LBL_2788 histidine kinase of a two-component regulator system; PFAM: response regulator receiver; hypothetical protein; histidine kinase dimerisation/phosphoacceptor; ATP-binding region ATPase domain protein; SMART: response regulator receiver; ATP-binding region ATPase domain protein; SPTR: histidine kinase of a two-component regulator system; TIGRFAM: PAS sensor protein; PFAM: histidine kinase; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Response regulator receiver domain; TIGRFAM: PAS domain S-box; signal transduction histidine kinase complement(4618551..4619900) Spirochaeta smaragdinae DSM 11293 9492409 YP_003805948.1 CDS Spirs_4281 NC_014364.1 4619975 4620595 D KEGG: bvu:BVU_3214 hypothetical protein; SPTR: membrane protein; hypothetical protein 4619975..4620595 Spirochaeta smaragdinae DSM 11293 9492410 YP_003805949.1 CDS Spirs_4282 NC_014364.1 4620571 4621989 D KEGG: cpi:Cpin_2056 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein 4620571..4621989 Spirochaeta smaragdinae DSM 11293 9492411 YP_003805950.1 CDS Spirs_4283 NC_014364.1 4622075 4622827 D COGs: COG0106 phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR006063; KEGG: syf:Synpcc7942_1829 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: histidine biosynthesis protein; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase 4622075..4622827 Spirochaeta smaragdinae DSM 11293 9492412 YP_003805951.1 CDS Spirs_4284 NC_014364.1 4622831 4623424 D COGs: COG0140 phosphoribosyl-ATP pyrophosphohydrolase; InterPro IPR008179; KEGG: bay:RBAM_032070 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; SPTR: phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-ATP pyrophosphohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; phosphoribosyl-ATP diphosphatase 4622831..4623424 Spirochaeta smaragdinae DSM 11293 9492413 YP_003805952.1 CDS Spirs_4285 NC_014364.1 4623432 4625279 D COGs: COG0646 methionine synthase I (cobalamin-dependent) methyltransferase domain; InterPro IPR003726:IPR003171; KEGG: sus:acid_7115 bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein; PFAM: homocysteine S-methyltransferase; methylenetetrahydrofolate reductase; SPTR: methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Homocysteine S-methyltransferase; homocysteine S-methyltransferase 4623432..4625279 Spirochaeta smaragdinae DSM 11293 9492414 YP_003805953.1 CDS Spirs_4286 NC_014364.1 4625276 4627267 D COGs: COG0021 transketolase; InterProIPR005474:IPR005475:IPR005476:IPR020826:IPR 005478; KEGG: tde:TDE1308 transketolase; PFAM: transketolase; transketolase; SPTR: transketolase; TIGRFAM: transketolase; PFAM: transketolase, thiamine diphosphate binding domain; transketolase, C-terminal domain; transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast; transketolase 4625276..4627267 Spirochaeta smaragdinae DSM 11293 9492415 YP_003805954.1 CDS Spirs_4287 NC_014364.1 4627411 4628319 R InterPro IPR000620; KEGG: shi:Shel_27470 predicted membrane protein; PFAM: protein of unknown function DUF6 transmembrane; SPTR: Predicted membrane protein; PFAM: EamA-like transporter family; hypothetical protein complement(4627411..4628319) Spirochaeta smaragdinae DSM 11293 9492416 YP_003805955.1 CDS Spirs_4288 NC_014364.1 4628485 4629363 D COGs: COG0583 transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: ava:Ava_0824 LysR family transcriptional regulator; PFAM: LysR substrate-binding; regulatory protein LysR; SPTR: LysR family transcriptional regulator; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family; LysR family transcriptional regulator 4628485..4629363 Spirochaeta smaragdinae DSM 11293 9492417 YP_003805956.1 CDS Spirs_4289 NC_014364.1 4629530 4631752 D COGs: COG1053 succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR010960:IPR007329:IPR003953; KEGG: amt:Amet_0327 flavocytochrome C; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FMN-binding domain protein; SPTR: Flavocytochrome C; TIGRFAM: flavocytochrome C; PFAM: FAD binding domain; FMN-binding domain; TIGRFAM: flavocytochrome C; flavocytochrome C 4629530..4631752 Spirochaeta smaragdinae DSM 11293 9492418 YP_003805957.1 CDS Spirs_4290 NC_014364.1 4632092 4633417 R COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: tdn:Suden_0947 transcriptional regulator; PFAM: AAA-4 family protein; SPTR: transcriptional regulator; PFAM: Divergent AAA domain; transcriptional regulator complement(4632092..4633417) Spirochaeta smaragdinae DSM 11293 9492419 YP_003805958.1 CDS Spirs_4291 NC_014364.1 4633731 4634567 R COGs: COG2801 transposase and inactivated derivatives; InterPro IPR001584; KEGG: maq:Maqu_0236 integrase catalytic subunit; PFAM: Integrase catalytic region; SPTR: Integrase catalytic region; PFAM: Integrase core domain; Integrase catalytic subunit complement(4633731..4634567) Spirochaeta smaragdinae DSM 11293 9492420 YP_003805959.1 CDS Spirs_4292 NC_014364.1 4634612 4634896 R InterPro IPR002514; KEGG: pvi:Cvib_1307 transposase IS3/IS911 family protein; PFAM: transposase IS3/IS911 family protein; SPTR: transposase IS3/IS911 family protein; PFAM: transposase; transposase IS3/IS911 family protein complement(4634612..4634896) Spirochaeta smaragdinae DSM 11293 9492421 YP_003805960.1 CDS Spirs_4293 NC_014364.1 4634910 4635614 R KEGG: cyp:PCC8801_2996 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4634910..4635614) Spirochaeta smaragdinae DSM 11293 9492422 YP_003805961.1 CDS Spirs_4294 NC_014364.1 4635699 4636256 R KEGG: pmo:Pmob_1495 HNH endonuclease; SPTR: HNH endonuclease; PFAM: HNH endonuclease; HNH endonuclease complement(4635699..4636256) Spirochaeta smaragdinae DSM 11293 9492423 YP_003805962.1 CDS Spirs_4295 NC_014364.1 4636696 4638528 R KEGG: tde:TDE0994 hypothetical protein; SPTR: uncharacterized protein; hypothetical protein complement(4636696..4638528) Spirochaeta smaragdinae DSM 11293 9492424 YP_003805963.1 CDS Spirs_4296 NC_014364.1 4638626 4640017 D COGs: COG4783 Zn-dependent protease contains TPR repeats; InterPro IPR001440:IPR013105:IPR019734:IPR013026; KEGG: tde:TDE0993 lipoprotein; PFAM: hypothetical protein; TPR repeat-containing protein; SPTR: lipoprotein; PFAM: Tetratricopeptide repeat; hypothetical protein 4638626..4640017 Spirochaeta smaragdinae DSM 11293 9492425 YP_003805964.1 CDS Spirs_4297 NC_014364.1 4640004 4641194 D COGs: COG1916 Uncharacterized homolog of PrgY (pheromone shutdown protein); InterPro IPR005230:IPR002816; KEGG: tde:TDE0026 TraB family protein; PFAM: TraB determinant protein; SPTR: TraB family protein; TIGRFAM: TraB family protein; PFAM: TraB family; TIGRFAM: pheromone shutdown-related protein TraB; TraB family protein 4640004..4641194 Spirochaeta smaragdinae DSM 11293 9492426 YP_003805965.1 CDS Spirs_4298 NC_014364.1 4641191 4642573 R COGs: COG1066 ATP-dependent serine protease; InterPro IPR004504:IPR003593; KEGG: tde:TDE2517 DNA repair protein RadA; SMART: AAA ATPase; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; PFAM: KaiC; TIGRFAM: DNA repair protein RadA; DNA repair protein RadA complement(4641191..4642573) Spirochaeta smaragdinae DSM 11293 9492427 YP_003805966.1 CDS Spirs_4299 NC_014364.1 4642625 4644883 D KEGG: cpi:Cpin_1999 hypothetical protein; SPTR: uncharacterized protein; TIGRFAM: glutamate--cysteine ligase/gamma-glutamylcysteine synthetase, Streptococcus agalactiae type; hypothetical protein 4642625..4644883 Spirochaeta smaragdinae DSM 11293 9492428 YP_003805967.1 CDS Spirs_4300 NC_014364.1 4644845 4645738 R COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: tde:TDE0606 ParB family protein; PFAM: ParB domain protein nuclease; SMART: ParB domain protein nuclease; SPTR: ParB family protein; TIGRFAM: parB-like partition protein; PFAM: ParB-like nuclease domain; TIGRFAM: ParB-like partition proteins; parB-like partition protein complement(4644845..4645738) Spirochaeta smaragdinae DSM 11293 9492429 YP_003805968.1 CDS Spirs_4301 NC_014364.1 4645731 4646489 R COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: tde:TDE0607 ParA family ATPase; PFAM: cobyrinic acid ac-diamide synthase; SPTR: sporulation initiation inhibitor protein soj; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; cobyrinic acid ac-diamide synthase complement(4645731..4646489) Spirochaeta smaragdinae DSM 11293 9492430 YP_003805969.1 CDS Spirs_4302 NC_014364.1 4646590 4646823 D COGs: COG0694 thioredoxin-like protein and domains; InterPro IPR001075; KEGG: sat:SYN_02452 NifU-like domain-containing protein; PFAM: nitrogen-fixing NifU domain protein; SPTR: NifU-like domain protein; PFAM: NifU-like domain; nitrogen-fixing NifU domain-containing protein 4646590..4646823 Spirochaeta smaragdinae DSM 11293 9492431 YP_003805970.1 CDS Spirs_4303 NC_014364.1 4646976 4648046 D COGs: COG1816 adenosine deaminase; InterPro IPR006330:IPR001365; KEGG: lic:LIC10459 adenosine deaminase; PFAM: adenosine/AMP deaminase; PRIAM: adenosine deaminase; SPTR: adenosine deaminase; TIGRFAM: adenosine deaminase; PFAM: adenosine/AMP deaminase; TIGRFAM: adenosine deaminase; adenosine deaminase 4646976..4648046 Spirochaeta smaragdinae DSM 11293 9492432 YP_003805971.1 CDS Spirs_4304 NC_014364.1 4648145 4649263 D KEGG: bgl:bglu_1g23870 transposase; SPTR: transposase; hypothetical protein 4648145..4649263 Spirochaeta smaragdinae DSM 11293 9492433 YP_003805972.1 CDS Spirs_4305 NC_014364.1 4649348 4651804 R COGs: COG0188 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) subunit alpha; InterPro IPR005743:IPR002205:IPR006691:IPR018120; KEGG: tde:TDE0295 DNA gyrase A subunit; PFAM: DNA gyrase/topoisomerase IV subunit A; DNA gyrase repeat beta-propeller; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA gyrase/topoisomerase IV subunit A; SPTR: DNA gyrase subunit alpha; TIGRFAM: DNA gyrase subunit alpha; PFAM: DNA gyrase C-terminal domain, beta-propeller; DNA gyrase/topoisomerase IV, subunit A; TIGRFAM: DNA gyrase subunit alpha; DNA gyrase subunit alpha complement(4649348..4651804) Spirochaeta smaragdinae DSM 11293 9492434 YP_003805973.1 CDS Spirs_4306 NC_014364.1 4651841 4653751 R COGs: COG0187 type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR011557:IPR003594:IPR013506:IPR006171:IPR 002288:IPR018522:IPR001241:IPR000565; KEGG: bcy:Bcer98_0005 DNA gyrase subunit B; PFAM: DNA topoisomerase type IIsubunit alpha B region 2 domain protein; ATP-binding region ATPase domain protein; TOPRIM domain protein; DNA gyrase subunit B domain protein; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase II; ATP-binding region ATPase domain protein; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase subunit beta; PFAM: Toprim domain; histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase subunit beta, carboxyl terminus; TIGRFAM: DNA gyrase subunit beta; DNA gyrase subunit beta complement(4651841..4653751) Spirochaeta smaragdinae DSM 11293 9492435 Spirs_R0002 tRNA Spirs_R0002 NC_014364.1 93503 93590 R tRNA-Ser complement(93503..93590) Spirochaeta smaragdinae DSM 11293 9488161 Spirs_R0003 tRNA Spirs_R0003 NC_014364.1 93616 93702 R tRNA-Ser complement(93616..93702) Spirochaeta smaragdinae DSM 11293 9488162 Spirs_R0004 tRNA Spirs_R0004 NC_014364.1 93714 93787 R tRNA-Arg complement(93714..93787) Spirochaeta smaragdinae DSM 11293 9488163 Spirs_R0005 tRNA Spirs_R0005 NC_014364.1 93796 93883 R tRNA-Ser complement(93796..93883) Spirochaeta smaragdinae DSM 11293 9488164 Spirs_R0006 tRNA Spirs_R0006 NC_014364.1 93901 93985 R tRNA-Ser complement(93901..93985) Spirochaeta smaragdinae DSM 11293 9488165 Spirs_R0007 tRNA Spirs_R0007 NC_014364.1 336002 336075 R tRNA-Ala complement(336002..336075) Spirochaeta smaragdinae DSM 11293 9488403 Spirs_R0008 tRNA Spirs_R0008 NC_014364.1 456124 456197 R tRNA-Arg complement(456124..456197) Spirochaeta smaragdinae DSM 11293 9488521 Spirs_R0009 tRNA Spirs_R0009 NC_014364.1 560554 560627 R tRNA-Met complement(560554..560627) Spirochaeta smaragdinae DSM 11293 9488620 Spirs_R0010 tRNA Spirs_R0010 NC_014364.1 915326 915397 R tRNA-Cys complement(915326..915397) Spirochaeta smaragdinae DSM 11293 9488952 Spirs_R0011 tRNA Spirs_R0011 NC_014364.1 997343 997415 D tRNA-Thr 997343..997415 Spirochaeta smaragdinae DSM 11293 9489023 Spirs_R0012 tRNA Spirs_R0012 NC_014364.1 997700 997773 D tRNA-Trp 997700..997773 Spirochaeta smaragdinae DSM 11293 9489025 Spirs_R0013 tRNA Spirs_R0013 NC_014364.1 1371883 1371967 R tRNA-Leu complement(1371883..1371967) Spirochaeta smaragdinae DSM 11293 9489370 Spirs_R0014 tRNA Spirs_R0014 NC_014364.1 1383471 1383542 R tRNA-Gly complement(1383471..1383542) Spirochaeta smaragdinae DSM 11293 9489381 Spirs_R0015 tRNA Spirs_R0015 NC_014364.1 1383569 1383650 R tRNA-Leu complement(1383569..1383650) Spirochaeta smaragdinae DSM 11293 9489382 Spirs_R0016 tRNA Spirs_R0016 NC_014364.1 1383698 1383770 R tRNA-Lys complement(1383698..1383770) Spirochaeta smaragdinae DSM 11293 9489383 Spirs_R0017 tRNA Spirs_R0017 NC_014364.1 1383784 1383860 R tRNA-Arg complement(1383784..1383860) Spirochaeta smaragdinae DSM 11293 9489384 Spirs_R0018 tRNA Spirs_R0018 NC_014364.1 1383869 1383943 R tRNA-His complement(1383869..1383943) Spirochaeta smaragdinae DSM 11293 9489385 Spirs_R0019 tRNA Spirs_R0019 NC_014364.1 1632343 1632415 D tRNA-Lys 1632343..1632415 Spirochaeta smaragdinae DSM 11293 9489610 Spirs_R0020 tRNA Spirs_R0020 NC_014364.1 1632493 1632567 D tRNA-Glu 1632493..1632567 Spirochaeta smaragdinae DSM 11293 9489611 Spirs_R0022 tRNA Spirs_R0022 NC_014364.1 1643748 1643821 D tRNA-Ala 1643748..1643821 Spirochaeta smaragdinae DSM 11293 9489623 Spirs_R0025 tRNA Spirs_R0025 NC_014364.1 1773614 1773684 D tRNA-Gly 1773614..1773684 Spirochaeta smaragdinae DSM 11293 9489752 Spirs_R0026 tRNA Spirs_R0026 NC_014364.1 1871505 1871579 D tRNA-Thr 1871505..1871579 Spirochaeta smaragdinae DSM 11293 9489834 Spirs_R0027 tRNA Spirs_R0027 NC_014364.1 1946829 1946899 D tRNA-Gln 1946829..1946899 Spirochaeta smaragdinae DSM 11293 9489896 Spirs_R0028 tRNA Spirs_R0028 NC_014364.1 1946908 1946979 D tRNA-Glu 1946908..1946979 Spirochaeta smaragdinae DSM 11293 9489897 Spirs_R0029 tRNA Spirs_R0029 NC_014364.1 1958410 1958482 D tRNA-Gln 1958410..1958482 Spirochaeta smaragdinae DSM 11293 9489913 Spirs_R0030 tRNA Spirs_R0030 NC_014364.1 2024798 2024869 R tRNA-Gly complement(2024798..2024869) Spirochaeta smaragdinae DSM 11293 9489966 Spirs_R0033 tRNA Spirs_R0033 NC_014364.1 2252518 2252599 R tRNA-Tyr complement(2252518..2252599) Spirochaeta smaragdinae DSM 11293 9490187 Spirs_R0034 tRNA Spirs_R0034 NC_014364.1 2252647 2252720 R tRNA-Thr complement(2252647..2252720) Spirochaeta smaragdinae DSM 11293 9490188 Spirs_R0035 tRNA Spirs_R0035 NC_014364.1 2329325 2329398 D tRNA-Asp 2329325..2329398 Spirochaeta smaragdinae DSM 11293 9490263 Spirs_R0036 tRNA Spirs_R0036 NC_014364.1 2329476 2329548 D tRNA-Pro 2329476..2329548 Spirochaeta smaragdinae DSM 11293 9490264 Spirs_R0037 tRNA Spirs_R0037 NC_014364.1 2511572 2511644 R tRNA-Met complement(2511572..2511644) Spirochaeta smaragdinae DSM 11293 9490451 Spirs_R0038 tRNA Spirs_R0038 NC_014364.1 2565121 2565207 D tRNA-Leu 2565121..2565207 Spirochaeta smaragdinae DSM 11293 9490496 Spirs_R0039 tRNA Spirs_R0039 NC_014364.1 2666060 2666135 D tRNA-Val 2666060..2666135 Spirochaeta smaragdinae DSM 11293 9490583 Spirs_R0040 tRNA Spirs_R0040 NC_014364.1 2700517 2700588 R tRNA-Met complement(2700517..2700588) Spirochaeta smaragdinae DSM 11293 9490632 Spirs_R0041 tRNA Spirs_R0041 NC_014364.1 2724720 2724795 D tRNA-Asn 2724720..2724795 Spirochaeta smaragdinae DSM 11293 9490655 Spirs_R0042 tRNA Spirs_R0042 NC_014364.1 2724805 2724876 D tRNA-Val 2724805..2724876 Spirochaeta smaragdinae DSM 11293 9490656 Spirs_R0044 tRNA Spirs_R0044 NC_014364.1 2976490 2976562 D tRNA-Pro 2976490..2976562 Spirochaeta smaragdinae DSM 11293 9490891 Spirs_R0045 tRNA Spirs_R0045 NC_014364.1 2976571 2976647 D tRNA-Arg 2976571..2976647 Spirochaeta smaragdinae DSM 11293 9490892 Spirs_R0046 tRNA Spirs_R0046 NC_014364.1 3117263 3117336 R tRNA-Val complement(3117263..3117336) Spirochaeta smaragdinae DSM 11293 9491034 Spirs_R0047 tRNA Spirs_R0047 NC_014364.1 3260777 3260850 R tRNA-Arg complement(3260777..3260850) Spirochaeta smaragdinae DSM 11293 9491158 Spirs_R0048 tRNA Spirs_R0048 NC_014364.1 3373747 3373822 D tRNA-Phe 3373747..3373822 Spirochaeta smaragdinae DSM 11293 9491266 Spirs_R0051 tRNA Spirs_R0051 NC_014364.1 3456437 3456510 R tRNA-Ile complement(3456437..3456510) Spirochaeta smaragdinae DSM 11293 9491344 Spirs_R0053 tRNA Spirs_R0053 NC_014364.1 3497363 3497436 D tRNA-Pro 3497363..3497436 Spirochaeta smaragdinae DSM 11293 9491380 Spirs_R0054 tRNA Spirs_R0054 NC_014364.1 3611677 3611749 D tRNA-Met 3611677..3611749 Spirochaeta smaragdinae DSM 11293 9491481 Spirs_R0055 tRNA Spirs_R0055 NC_014364.1 3839691 3839764 D tRNA-Asp 3839691..3839764 Spirochaeta smaragdinae DSM 11293 9491691 Spirs_R0056 tRNA Spirs_R0056 NC_014364.1 4062765 4062851 D tRNA-Leu 4062765..4062851 Spirochaeta smaragdinae DSM 11293 9491896 Spirs_R0057 tRNA Spirs_R0057 NC_014364.1 4367098 4367181 R tRNA-Leu complement(4367098..4367181) Spirochaeta smaragdinae DSM 11293 9492161 Spirs_R0058 tRNA Spirs_R0058 NC_014364.1 4414564 4414637 D tRNA-Ala 4414564..4414637 Spirochaeta smaragdinae DSM 11293 9492209 Spirs_R0021 rRNA Spirs_R0021 NC_014364.1 1642104 1643633 D 16S ribosomal RNA 1642104..1643633 Spirochaeta smaragdinae DSM 11293 9489622 Spirs_R0023 rRNA Spirs_R0023 NC_014364.1 1643967 1646947 D 23S ribosomal RNA 1643967..1646947 Spirochaeta smaragdinae DSM 11293 9489624 Spirs_R0024 rRNA Spirs_R0024 NC_014364.1 1646998 1647108 D 5S ribosomal RNA 1646998..1647108 Spirochaeta smaragdinae DSM 11293 9489625 Spirs_R0049 rRNA Spirs_R0049 NC_014364.1 3453187 3453297 R 5S ribosomal RNA complement(3453187..3453297) Spirochaeta smaragdinae DSM 11293 9491342 Spirs_R0050 rRNA Spirs_R0050 NC_014364.1 3453348 3456328 R 23S ribosomal RNA complement(3453348..3456328) Spirochaeta smaragdinae DSM 11293 9491343 Spirs_R0052 rRNA Spirs_R0052 NC_014364.1 3456594 3458122 R 16S ribosomal RNA complement(3456594..3458122) Spirochaeta smaragdinae DSM 11293 9491345