-- dump date 20140620_063927 -- class Genbank::CDS -- table cds_note -- id note YP_001092133.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_001092134.1 KEGG: son:SO0009 DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain YP_001092135.1 Required for DNA replication; binds preferentially to single-stranded, linear DNA YP_001092136.1 KEGG: son:SO0011 DNA gyrase subunit B; TIGRFAM: DNA gyrase, B subunit; PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; TOPRIM domain protein; DNA topoisomerase, type IIA, subunit B, region 2 domain protein; SMART: DNA topoisomerase II YP_001092138.1 PFAM: LamB/YcsF family protein; KEGG: reu:Reut_A0089 LamB/YcsF YP_001092139.1 TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2 YP_001092140.1 PFAM: Allophanate hydrolase subunit 1; KEGG: sfv:SFV_0624 putative carboxylase YP_001092141.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001092142.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_001092143.1 KEGG: shm:Shewmr7_0010 DNA-3-methyladenine glycosylase I; TIGRFAM: DNA-3-methyladenine glycosylase I; PFAM: methyladenine glycosylase YP_001092145.1 PFAM: amidohydrolase; WD40 domain protein beta Propeller; KEGG: sfr:Sfri_0009 amidohydrolase YP_001092146.1 KEGG: she:Shewmr4_0012 hypothetical protein YP_001092147.1 TusA; transfers sulfur to TusBCD complex; involved in thiouridation of U34 position of some tRNAs YP_001092148.1 TIGRFAM: ybaK/ebsC protein; PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: vfi:VF1792 regulatory protein YP_001092149.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB1061 hypothetical protein YP_001092150.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001092151.1 includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_001092152.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_001092153.1 PFAM: protein of unknown function UPF0029; KEGG: she:Shewmr4_0020 protein of unknown function UPF0029 YP_001092154.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shm:Shewmr7_0019 potassium uptake protein, TrkH family YP_001092155.1 KEGG: shm:Shewmr7_0020 protoporphyrinogen oxidase YP_001092156.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_0021 transcriptional regulator, ArsR family YP_001092157.1 KEGG: sfr:Sfri_0019 protoporphyrinogen oxidase YP_001092158.1 KEGG: shm:Shewmr7_3934 hypothetical protein YP_001092159.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: son:SO4697 glutathione S-transferase YP_001092160.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pen:PSEEN2735 transcriptional regulator, LysR family YP_001092161.1 KEGG: shm:Shewmr7_3932 conserved hypothetical 3-methyladenine DNA glycosylase YP_001092162.1 KEGG: sfr:Sfri_1989 hypothetical protein YP_001092163.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3837 efflux transporter, RND family, MFP subunit YP_001092164.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3929 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family YP_001092165.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: son:SO0152 hypothetical carboxypeptidase YP_001092166.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0139 methyltransferase type 11 YP_001092167.1 KEGG: shm:Shewmr7_0138 lipoprotein, putative YP_001092168.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: sde:Sde_1770 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like YP_001092169.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: sde:Sde_1770 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like YP_001092170.1 PFAM: Excinuclease ABC, C subunit domain protein; KEGG: she:Shewmr4_0137 excinuclease ABC, C subunit domain protein YP_001092171.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: son:SO0144 protease II YP_001092172.1 DHBP synthase; functions during riboflavin biosynthesis YP_001092173.1 KEGG: she:Shewmr4_0134 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; Nitrate and nitrite sensing domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001092174.1 PFAM: Ferritin, Dps family protein; KEGG: shm:Shewmr7_0127 ferritin, Dps family protein YP_001092175.1 KEGG: cps:CPS_4517 hypothetical protein YP_001092176.1 PFAM: acriflavin resistance protein; KEGG: sdn:Sden_3430 acriflavin resistance protein YP_001092177.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sdn:Sden_3429 secretion protein HlyD YP_001092178.1 TIGRFAM: molybdenum cofactor synthesis domain; PFAM: molybdopterin binding domain; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: son:SO0138 molybdopterin biosynthesis MoeA protein YP_001092179.1 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase YP_001092180.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_0827 short-chain dehydrogenase/reductase SDR YP_001092181.1 TIGRFAM: choline/carnitine/betaine transporter; PFAM: BCCT transporter; KEGG: vpa:VP1905 transporter, BCCT family YP_001092182.1 3'-5' exonuclease of DNA polymerase III YP_001092183.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: vpa:VP1902 CBS domain-containing protein YP_001092184.1 TIGRFAM: DNA binding domain, excisionase family; KEGG: she:Shewmr4_3713 DNA binding domain, excisionase family YP_001092185.1 PFAM: formate dehydrogenase, subunit FdhD; KEGG: she:Shewmr4_3714 formate dehydrogenase, subunit FdhD YP_001092186.1 KEGG: sfr:Sfri_0052 hypothetical protein YP_001092187.1 KEGG: son:SO4505 hypothetical protein YP_001092188.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: son:SO4506 iron-sulfur cluster-binding protein YP_001092189.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: son:SO4507 TorA specific chaperone, putative YP_001092190.1 KEGG: she:Shewmr4_3719 twin-arginine translocation pathway signal YP_001092191.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: sfr:Sfri_0057 twin-arginine translocation pathway signal YP_001092192.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3792 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001092193.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: son:SO4511 formate dehydrogenase, C subunit, putative YP_001092194.1 KEGG: son:SO4512 hypothetical protein YP_001092195.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: shm:Shewmr7_3795 twin-arginine translocation pathway signal YP_001092196.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3725 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001092197.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_3797 formate dehydrogenase, gamma subunit YP_001092199.1 KEGG: sfr:Sfri_3099 methylation site containing protein YP_001092200.1 PFAM: fumarate lyase; KEGG: pen:PSEEN1085 fumarate hydratase class II YP_001092201.1 KEGG: sdn:Sden_0559 hypothetical protein YP_001092202.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sfr:Sfri_0073 iron-containing alcohol dehydrogenase YP_001092203.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: sfr:Sfri_0074 transcriptional regulator, AraC family protein YP_001092205.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001092207.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: nar:Saro_1420 antibiotic biosynthesis monooxygenase YP_001092208.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0961 GCN5-related N-acetyltransferase YP_001092209.1 PFAM: PfkB domain protein; KEGG: she:Shewmr4_0267 PfkB domain protein YP_001092210.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: cps:CPS_0147 hydrolase, alpha/beta fold family YP_001092211.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vpa:VPA1277 sensor histidine kinase YP_001092212.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_04118 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_001092213.1 KEGG: sdn:Sden_0560 hypothetical protein YP_001092214.1 PFAM: 3-alpha; MOSC domain containing protein; KEGG: she:Shewmr4_0269 MOSC domain containing protein YP_001092215.1 KEGG: sfr:Sfri_0079 hypothetical protein YP_001092216.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3750 methyl-accepting chemotaxis sensory transducer YP_001092217.1 PFAM: FAD dependent oxidoreductase; electron transfer flavoprotein-ubiquinone oxidoreductase; KEGG: son:SO4453 electron transfer flavoprotein-ubiquinone oxidoreductase, putative YP_001092218.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001092219.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdenum cofactor biosynthesis protein B; PFAM: molybdopterin binding domain; KEGG: pat:Patl_2158 molybdenum cofactor biosynthesis protein B YP_001092220.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_001092221.1 TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: shm:Shewmr7_3746 molybdopterin converting factor, subunit 1 YP_001092222.1 PFAM: molybdopterin biosynthesis MoaE; KEGG: she:Shewmr4_0276 molybdopterin biosynthesis MoaE YP_001092223.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_3744 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001092224.1 TIGRFAM: molybdate ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3743 molybdate ABC transporter, inner membrane subunit YP_001092225.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3742 ABC transporter-related protein YP_001092226.1 PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; conserved hypothetical protein 156; KEGG: vpa:VPA0694 hypothetical protein YP_001092227.1 KEGG: shm:Shewmr7_3741 hypothetical protein YP_001092228.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3740 two component transcriptional regulator, winged helix family YP_001092229.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4427 sensor histidine kinase YP_001092230.1 TIGRFAM: pseudouridine synthase Rlu family protein, TIGR01621; PFAM: pseudouridine synthase; KEGG: she:Shewmr4_0283 pseudouridine synthase Rlu family protein, TIGR01621 YP_001092231.1 PFAM: protein of unknown function UPF0057; KEGG: shm:Shewmr7_3736 protein of unknown function UPF0057 YP_001092232.1 PFAM: Endoribonuclease L-PSP; KEGG: bha:BH3085 hypothetical protein YP_001092233.1 KEGG: shm:Shewmr7_3732 hypothetical protein YP_001092234.1 PFAM: sodium/glutamate symporter; KEGG: she:Shewmr4_1482 sodium/glutamate symporter YP_001092235.1 PFAM: protein of unknown function DUF333; KEGG: shm:Shewmr7_0123 protein of unknown function DUF333 YP_001092236.1 SMART: peptidase M14, carboxypeptidase A; KEGG: pat:Patl_4232 peptidase M14, carboxypeptidase A YP_001092237.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_001092238.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO4617 DNA-damage-inducible protein F YP_001092239.1 PFAM: polysaccharide deacetylase; KEGG: shm:Shewmr7_3874 polysaccharide deacetylase YP_001092240.1 PFAM: CheB methylesterase; response regulator receiver; KEGG: xcb:XC_2323 glutamate methylesterase YP_001092241.1 PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 12; KEGG: sde:Sde_3104 biotin biosynthesis protein BioC YP_001092242.1 PFAM: chemotaxis sensory transducer; PAS fold-4 domain protein; SMART: PAS domain containing protein; KEGG: cvi:CV3438 probable methyl-accepting chemotaxis protein YP_001092243.1 PFAM: CheW domain protein; KEGG: sde:Sde_3106 biotin synthase YP_001092244.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: tcx:Tcr_1612 CheA signal transduction histidine kinase YP_001092245.1 PFAM: response regulator receiver; KEGG: hch:HCH_00454 FOG: CheY-like receiver YP_001092247.1 PFAM: electron transport protein SCO1/SenC; KEGG: son:SO4615 SCO1/SenC family protein YP_001092248.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001092249.1 PFAM: cytochrome oxidase assembly; KEGG: sdn:Sden_3523 cytochrome oxidase assembly YP_001092250.1 KEGG: sfr:Sfri_0252 hypothetical protein YP_001092251.1 KEGG: shm:Shewmr7_3869 hypothetical protein YP_001092252.1 KEGG: sfr:Sfri_0254 hypothetical protein YP_001092253.1 PFAM: cytochrome c oxidase, subunit III; KEGG: shm:Shewmr7_3867 cytochrome c oxidase, subunit III YP_001092254.1 involved in the insertion of copper into subunit I of cytochrome C oxidase YP_001092255.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3865 cytochrome-c oxidase YP_001092256.1 PFAM: cytochrome c oxidase, subunit II; cytochrome c, class I; cytochrome C oxidase subunit II, transmembrane region; KEGG: shm:Shewmr7_3864 cytochrome c oxidase, subunit II YP_001092257.1 KEGG: sfr:Sfri_0259 hypothetical protein YP_001092258.1 Represses a number of genes involved in the response to DNA damage YP_001092259.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_0162 HAD-superfamily hydrolase, subfamily IA, variant 3 YP_001092260.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_001092261.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: sfr:Sfri_0118 3'(2'),5'-bisphosphate nucleotidase YP_001092262.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0171 GCN5-related N-acetyltransferase YP_001092263.1 KEGG: she:Shewmr4_0172 transcriptional regulator, TetR family YP_001092264.1 PFAM: phospholipid/glycerol acyltransferase; major facilitator superfamily MFS_1; KEGG: son:SO0194 acyltransferase family protein YP_001092265.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_001092266.1 catalyzes the formation of selenophosphate from selenide and ATP YP_001092267.1 PFAM: fatty acid desaturase; KEGG: she:Shewmr4_0176 stearoyl-CoA 9-desaturase YP_001092268.1 negatively controls the expression of fabA and fabB, genes involved in the unsaturated fatty acid biosynthesis YP_001092269.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_001092270.1 converts L-glutamate to D-glutamate, a component of peptidoglycan YP_001092271.1 PFAM: RNP-1 like RNA-binding protein; KEGG: shm:Shewmr7_0175 RNP-1 like RNA-binding protein YP_001092272.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_001092273.1 catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon YP_001092274.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_001092275.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001092276.1 forms a complex with SecY and SecG; SecYEG forms a putative protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force YP_001092277.1 KEGG: sfr:Sfri_0136 NusG antitermination factor; TIGRFAM: transcription termination/antitermination factor NusG; PFAM: transcription antitermination protein NusG; KOW domain protein; SMART: NGN domain protein; KOW (Kyrpides, Ouzounis, Woese) domain protein YP_001092278.1 binds directly to 23S ribosomal RNA YP_001092279.1 PFAM: ribosomal protein L1; KEGG: shm:Shewmr7_0184 ribosomal protein L1 YP_001092280.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_001092281.1 TIGRFAM: ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12-like; KEGG: she:Shewmr4_0191 ribosomal protein L7/L12 YP_001092282.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_001092283.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_001092284.1 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance YP_001092285.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_001092286.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001092287.1 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu YP_001092288.1 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex YP_001092289.1 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin YP_001092290.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_001092291.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_001092292.1 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation YP_001092293.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_001092294.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_001092295.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_001092296.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_001092297.1 one of the stabilizing components for the large ribosomal subunit YP_001092298.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_001092299.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_001092300.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_001092301.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_001092302.1 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif YP_001092303.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_001092304.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_001092305.1 binds 5S rRNA along with protein L5 and L25 YP_001092306.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_001092307.1 PFAM: ribosomal protein L30; KEGG: she:Shewmr4_0217 ribosomal protein L30 YP_001092308.1 late assembly protein YP_001092309.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_001092310.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group have the motif YP_001092311.1 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA YP_001092312.1 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3 YP_001092313.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_001092314.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_001092315.1 is a component of the macrolide binding site in the peptidyl transferase center YP_001092316.1 KEGG: she:Shewmr4_0226 hypothetical protein YP_001092317.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_001092318.1 PFAM: Heme exporter protein D (CcmD); KEGG: son:SO0260 heme exporter protein CcmD YP_001092319.1 TIGRFAM: heme exporter protein CcmC; PFAM: cytochrome c assembly protein; KEGG: sfr:Sfri_0177 heme exporter protein CcmC YP_001092320.1 TIGRFAM: heme exporter protein CcmB; PFAM: cytochrome c-type biogenesis protein CcmB; KEGG: son:SO0262 heme exporter protein CcmB YP_001092321.1 ATP-binding protein; required for proper cytochrome c maturation YP_001092322.1 PFAM: cytochrome c, class I; KEGG: sfr:Sfri_0180 cytochrome c, class I YP_001092323.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0228 TPR repeat-containing protein YP_001092324.1 TIGRFAM: cytochrome c-type biogenesis protein CcmF; PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_0229 cytochrome c-type biogenesis protein CcmF YP_001092325.1 TIGRFAM: periplasmic protein thiol--disulphide oxidoreductase DsbE; PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_0230 periplasmic protein thiol--disulphide oxidoreductase DsbE YP_001092326.1 PFAM: cytochrome C biogenesis protein; KEGG: shm:Shewmr7_0231 cytochrome c biogenesis protein YP_001092327.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_0232 redoxin domain protein YP_001092328.1 PFAM: protein of unknown function DUF796; KEGG: pae:PA0085 hypothetical protein YP_001092329.1 TIGRFAM: competence/damage-inducible protein CinA; PFAM: molybdopterin binding domain; CinA domain protein; KEGG: shm:Shewmr7_0233 competence/damage-inducible protein CinA YP_001092330.1 PFAM: protein of unknown function DUF1439; KEGG: son:SO0273 hypothetical protein YP_001092331.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_001092332.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_001092333.1 catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate YP_001092334.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_001092335.1 catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation YP_001092336.1 catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming YP_001092337.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_001092338.1 TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase; KEGG: sfr:Sfri_0369 penicillin-binding protein, 1A family protein YP_001092339.1 TIGRFAM: type IV pilus assembly protein PilM; KEGG: shm:Shewmr7_0242 type IV pilus assembly protein PilM YP_001092340.1 PFAM: Fimbrial assembly family protein; KEGG: shm:Shewmr7_0243 fimbrial assembly family protein YP_001092341.1 PFAM: Pilus assembly protein, PilO; KEGG: son:SO0283 type IV pilus biogenesis protein PilO YP_001092342.1 PFAM: Pilus assembly protein, PilQ; KEGG: shm:Shewmr7_0245 pilus assembly protein, PilQ YP_001092343.1 TIGRFAM: type IV pilus secretin PilQ; PFAM: type II and III secretion system protein; NolW domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3699 type IV pilus secretin PilQ YP_001092344.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_001092345.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_001092346.1 PFAM: Sporulation domain protein; KEGG: son:SO0288 DamX domain protein YP_001092347.1 KEGG: sdn:Sden_0264 DNA adenine methylase; TIGRFAM: DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase YP_001092348.1 KEGG: sfr:Sfri_0379 hypothetical protein YP_001092349.1 KEGG: shm:Shewmr7_0252 hypothetical protein YP_001092350.1 PFAM: ribulose-phosphate 3-epimerase; Orotidine 5'-phosphate decarboxylase; KEGG: son:SO0292 ribulose-phosphate 3-epimerase YP_001092351.1 KEGG: son:SO0293 phosphoglycolate phosphatase; TIGRFAM: phosphoglycolate phosphatase ; HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001092352.1 catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001092353.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0295 transcriptional regulator, LysR family YP_001092354.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_3688 protein of unknown function DUF6, transmembrane YP_001092355.1 PFAM: transport-associated; SMART: Transport-associated and nodulation region, bacteria; KEGG: shm:Shewmr7_0258 transport-associated YP_001092356.1 TIGRFAM: phosphoheptose isomerase; KEGG: shm:Shewmr7_0259 phosphoheptose isomerase YP_001092357.1 PFAM: protein of unknown function UPF0102; KEGG: she:Shewmr4_3685 protein of unknown function UPF0102 YP_001092358.1 PFAM: LppC family lipoprotein; KEGG: shm:Shewmr7_0261 LppC family lipoprotein YP_001092359.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0262 protein of unknown function UPF0011 YP_001092360.1 SMART: extracellular solute-binding protein, family 3; KEGG: hch:HCH_06608 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain YP_001092361.1 KEGG: sfr:Sfri_0393 hypothetical protein YP_001092362.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO0308 hypothetical protein YP_001092363.1 KEGG: shm:Shewmr7_0274 hypothetical protein YP_001092364.1 PFAM: Radical SAM domain protein; Radical SAM N-terminal domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: she:Shewmr4_3670 radical SAM N-terminal domain protein YP_001092365.1 PFAM: protein of unknown function DUF1232; KEGG: she:Shewmr4_3655 protein of unknown function DUF1232 YP_001092366.1 PFAM: isochorismatase hydrolase; KEGG: cps:CPS_0771 isochorismatase family protein YP_001092367.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0770 transcriptional regulator, LysR family YP_001092368.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_3839 methyl-accepting chemotaxis protein YP_001092369.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_3663 porin, gram-negative type YP_001092370.1 TIGRFAM: formate dehydrogenase, gamma subunit; KEGG: shm:Shewmr7_0283 formate dehydrogenase, gamma subunit YP_001092371.1 PFAM: cytoplasmic chaperone TorD family protein; KEGG: shm:Shewmr7_0284 cytoplasmic chaperone TorD family protein YP_001092372.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_0285 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001092373.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: shm:Shewmr7_0286 twin-arginine translocation pathway signal YP_001092374.1 PFAM: regulatory protein, LysR; KEGG: she:Shewmr4_3657 transcriptional regulator, LysR family YP_001092375.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: vvy:VV2222 tetrathionate reductase, subunit B YP_001092376.1 PFAM: molydopterin dinucleotide-binding region; KEGG: ppr:PBPRB1372 hypothetical tetrathionate reductase YP_001092377.1 KEGG: shm:Shewmr7_0292 hypothetical protein YP_001092378.1 KEGG: pae:PA1038 hypothetical protein YP_001092379.1 PFAM: GCN5-related N-acetyltransferase; KEGG: psp:PSPPH_3302 ribosomal protein alanine acetyltransferase YP_001092380.1 PFAM: GCN5-related N-acetyltransferase; KEGG: vvy:VV0134 predicted acetyltransferase YP_001092381.1 PFAM: regulatory protein, MerR; Methyltransferase type 11; Methyltransferase type 12; KEGG: vvy:VV0135 putative transcriptional regulator YP_001092382.1 PFAM: phage integrase family protein; KEGG: vvu:VV20655 integrase YP_001092383.1 KEGG: vvy:VV0136 hypothetical protein YP_001092384.1 PFAM: secretion protein HlyD family protein; KEGG: vvy:VV0137 multidrug resistance efflux pump YP_001092385.1 KEGG: vvy:VV0138 hypothetical protein YP_001092386.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: vvy:VV0139 hypothetical protein YP_001092387.1 KEGG: son:SO0322 hypothetical protein YP_001092388.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: sdn:Sden_0280 peptidase S9, prolyl oligopeptidase active site region YP_001092389.1 KEGG: shm:Shewmr7_0294 hypothetical protein YP_001092390.1 KEGG: sfr:Sfri_0404 hypothetical protein YP_001092391.1 KEGG: she:Shewmr4_3647 hypothetical protein YP_001092392.1 KEGG: sfr:Sfri_0406 hypothetical protein YP_001092393.1 PFAM: protein of unknown function UPF0061; KEGG: she:Shewmr4_3645 protein of unknown function UPF0061 YP_001092394.1 KEGG: son:SO0331 hypothetical protein YP_001092395.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_001092396.1 PFAM: DSBA oxidoreductase; KEGG: sdn:Sden_0285 DsbA oxidoreductase YP_001092397.1 PFAM: protein of unknown function DUF1107; KEGG: son:SO0334 hypothetical protein YP_001092398.1 PFAM: protein of unknown function DUF904; KEGG: son:SO0335 hypothetical protein YP_001092399.1 PFAM: Modulator of Rho-dependent transcription termination; KEGG: shm:Shewmr7_0308 transcriptional antiterminator, Rof YP_001092400.1 PFAM: protein of unknown function DUF1223; KEGG: shm:Shewmr7_0309 protein of unknown function DUF1223 YP_001092401.1 KEGG: ppr:PBPRB1460 hypothetical protein YP_001092402.1 KEGG: lpp:lpp1568 phospholipase YP_001092403.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: she:Shewmr4_0303 hypothetical protein YP_001092404.1 KEGG: son:SO1411 hypothetical protein YP_001092405.1 KEGG: she:Shewmr4_0301 hypothetical protein YP_001092406.1 KEGG: son:SO1413 tetraheme cytochrome c, putative YP_001092407.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0299 flavocytochrome c YP_001092408.1 PFAM: regulatory protein, TetR; KEGG: son:SO1415 transcriptional regulator, TetR family YP_001092409.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001092411.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: shm:Shewmr7_0316 transcriptional regulator, GntR family YP_001092412.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_3626 phospholipid/glycerol acyltransferase YP_001092413.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_0319 phospholipid/glycerol acyltransferase YP_001092414.1 KEGG: son:SO0349 magnesium chelatase family protein; TIGRFAM: Mg chelatase, subunit ChlI; PFAM: magnesium chelatase, ChlI subunit; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001092415.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: son:SO4351 CBS domain protein YP_001092416.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sdn:Sden_0972 GGDEF domain YP_001092417.1 SMART: extracellular solute-binding protein, family 3; KEGG: she:Shewmr4_0358 ABC-type amino acid transport/signal transduction systems periplasmic component/domain-like protein YP_001092418.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_001092419.1 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis YP_001092420.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_001092421.1 KEGG: shm:Shewmr7_3663 acetolactate synthase small subunit YP_001092422.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_001092423.1 catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis YP_001092424.1 threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway YP_001092425.1 PFAM: aminotransferase, class V; KEGG: son:SO4343 aminotransferase, class V YP_001092427.1 PFAM: heat shock protein Hsp20; KEGG: bja:blr7961 probable HspC2 heat shock protein YP_001092428.1 KEGG: she:Shewmr4_0503 hypothetical protein YP_001092429.1 KEGG: pat:Patl_0737 Zn-dependent hydrolase of the beta-lactamase fold YP_001092430.1 PFAM: regulatory protein, TetR; KEGG: hch:HCH_03535 transcriptional regulator YP_001092431.1 PFAM: sodium:neurotransmitter symporter; KEGG: son:SO4339 sodium-dependent transporter, putative YP_001092432.1 PFAM: regulatory protein, AsnC/Lrp family; KEGG: son:SO4337 transcriptional regulator, AsnC family YP_001092433.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: shm:Shewmr7_3657 phosphoesterase, PA-phosphatase related YP_001092434.1 PFAM: Inner membrane CreD family protein; KEGG: shm:Shewmr7_3656 inner membrane CreD family protein YP_001092435.1 PFAM: protein of unknown function DUF526; KEGG: shm:Shewmr7_3651 protein of unknown function DUF526 YP_001092436.1 TIGRFAM: ATP-dependent DNA helicase Rep; PFAM: UvrD/REP helicase; KEGG: son:SO4325 ATP-dependent DNA helicase Rep YP_001092437.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_0377 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001092438.1 PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO4323 GGDEF domain protein YP_001092439.1 KEGG: son:SO4322 hypothetical protein YP_001092440.1 PFAM: OmpA/MotB domain protein; KEGG: sdn:Sden_0380 OmpA/MotB YP_001092441.1 TIGRFAM: type I secretion outer membrane protein, TolC family; PFAM: outer membrane efflux protein; KEGG: sdn:Sden_0381 type I secretion outer membrane protein, TolC YP_001092442.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3644 type I secretion membrane fusion protein, HlyD family YP_001092443.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4318 toxin secretion ATP-binding protein YP_001092444.1 TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; von Willebrand factor, type A; KEGG: shm:Shewmr7_3642 putative outer membrane adhesin like protein YP_001092445.1 KEGG: sdn:Sden_0384 hypothetical protein; TIGRFAM: putative outer membrane adhesin like proteiin; PFAM: Hemolysin-type calcium-binding region; SMART: Cadherin YP_001092446.1 PFAM: HemY domain protein; KEGG: she:Shewmr4_0385 HemY domain protein YP_001092447.1 PFAM: protein of unknown function DUF513, hemX; KEGG: she:Shewmr4_0386 protein of unknown function DUF513, HemX YP_001092448.1 PFAM: Uroporphyrinogen III synthase HEM4; KEGG: son:SO4314 uroporphyrinogen-III synthase YP_001092449.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_001092450.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_001092451.1 PFAM: Frataxin family protein; KEGG: shm:Shewmr7_3636 frataxin family protein YP_001092453.1 TIGRFAM: diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_3634 diaminopimelate decarboxylase YP_001092454.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_001092455.1 PFAM: protein of unknown function DUF484; KEGG: sfr:Sfri_0446 protein of unknown function DUF484 YP_001092456.1 TIGRFAM: tyrosine recombinase XerC; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: shm:Shewmr7_3631 tyrosine recombinase XerC YP_001092457.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: shm:Shewmr7_3630 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001092458.1 PFAM: HupE/UreJ protein; KEGG: she:Shewmr4_0396 HupE/UreJ protein YP_001092459.1 PFAM: protein of unknown function DUF542, ScdA domain protein; Hemerythrin HHE cation binding domain protein; KEGG: she:Shewmr4_0398 hemerythrin HHE cation binding domain protein YP_001092460.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_001092461.1 TIGRFAM: putative TIM-barrel protein, nifR3 family; PFAM: dihydrouridine synthase, DuS; dihydroorotate dehydrogenase; KEGG: son:SO0394 tRNA-dihydrouridine synthase B YP_001092462.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_001092463.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit YP_001092464.1 PFAM: fumarate reductase respiratory complex, transmembrane subunit; KEGG: she:Shewmr4_0403 fumarate reductase respiratory complex, transmembrane subunit YP_001092465.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001092466.1 part of three member fumarate reductase enzyme complex FrdABC which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdC is the cytochrome b-556 subunit; the catalytic subunits are similar to succinate dehydrogenase SdhAB YP_001092467.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0402 transcriptional regulator, LysR family YP_001092468.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_001092469.1 TIGRFAM: thioredoxin; PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_3615 thioredoxin YP_001092470.1 enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation YP_001092471.1 PFAM: Ppx/GppA phosphatase; KEGG: shm:Shewmr7_3613 Ppx/GppA phosphatase YP_001092472.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sdn:Sden_2404 TonB-dependent receptor YP_001092473.1 KEGG: son:SO0409 hypothetical protein YP_001092474.1 KEGG: son:SO0474 hypothetical protein YP_001092475.1 PFAM: Na+/H+ antiporter NhaC; KEGG: sdn:Sden_3405 Na+/H+ antiporter NhaC YP_001092476.1 PFAM: Redoxin domain protein; KEGG: son:SO0476 thioredoxin, putative YP_001092477.1 PFAM: cytochrome C biogenesis protein; KEGG: son:SO0477 cytochrome c-type biogenesis protein NrfF precursor YP_001092478.1 PFAM: cytochrome c assembly protein; KEGG: she:Shewmr4_0487 cytochrome c-type biogenesis protein CcmF YP_001092479.1 KEGG: shm:Shewmr7_3542 cytochrome c, putative YP_001092480.1 SMART: Rhodanese domain protein; KEGG: son:SO0480 hypothetical protein YP_001092481.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: she:Shewmr4_0490 FKBP-type peptidyl-prolyl isomerase domain protein YP_001092482.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO0482 formate-dependent nitrite reductase, NrfG protein YP_001092483.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_0492 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001092484.1 PFAM: Polysulphide reductase, NrfD; KEGG: she:Shewmr4_0493 polysulphide reductase, NrfD YP_001092485.1 PFAM: NosL family protein; KEGG: shm:Shewmr7_3536 NosL family protein YP_001092486.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: shm:Shewmr7_3535 periplasmic copper-binding protein YP_001092487.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0496 ABC transporter-related protein YP_001092488.1 KEGG: son:SO0488 copper ABC transporter, permease protein YP_001092489.1 PFAM: transcriptional regulator domain protein; KEGG: shm:Shewmr7_3532 transcriptional regulator, CadC YP_001092490.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_001092491.1 TIGRFAM: UbiD family decarboxylases; PFAM: Carboxylyase-related protein; KEGG: shm:Shewmr7_3525 UbiD family decarboxylases YP_001092492.1 KEGG: sfr:Sfri_3388 hypothetical protein YP_001092493.1 KEGG: she:Shewmr4_1481 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001092494.1 manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily YP_001092495.1 KEGG: vfi:VF0366 MshA, mannose-sensitive haemaglutinin YP_001092496.1 KEGG: sfr:Sfri_0225 hypothetical protein YP_001092497.1 TIGRFAM: ubiquinol oxidase, subunit II; PFAM: cytochrome c oxidase, subunit II; COX aromatic rich domain protein; KEGG: she:Shewmr4_3823 ubiquinol oxidase, subunit II YP_001092498.1 PFAM: cytochrome c oxidase, subunit I; KEGG: shm:Shewmr7_3915 cytochrome-c oxidase YP_001092499.1 PFAM: cytochrome c oxidase, subunit III; KEGG: she:Shewmr4_3825 cytochrome c oxidase, subunit III YP_001092500.1 PFAM: cytochrome C oxidase subunit IV; KEGG: shm:Shewmr7_3917 cytochrome c oxidase subunit IV YP_001092501.1 converts protoheme IX and farnesyl diphosphate to heme O YP_001092502.1 PFAM: helix-turn-helix- domain containing protein, AraC type; transcription activator, effector binding; KEGG: stt:t3096 possible AraC-family transcriptional regulator YP_001092503.1 KEGG: sfr:Sfri_3594 hypothetical protein YP_001092504.1 PFAM: protein of unknown function DUF971; KEGG: she:Shewmr4_3523 protein of unknown function DUF971 YP_001092505.1 heat shock protein involved in degradation of misfolded proteins YP_001092506.1 heat shock protein involved in degradation of misfolded proteins YP_001092507.1 PFAM: Curlin associated repeat protein; KEGG: sfr:Sfri_1514 curlin associated repeat protein YP_001092508.1 PFAM: Sporulation domain protein; KEGG: sfr:Sfri_3763 sporulation domain protein YP_001092509.1 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase YP_001092510.1 KEGG: son:SO4122 primosomal protein N'; TIGRFAM: primosomal protein N'; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001092511.1 KEGG: sdn:Sden_3355 hypothetical protein YP_001092512.1 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome YP_001092513.1 PFAM: nuclease (SNase domain protein); KEGG: noc:Noc_1218 micrococcal nuclease (SNase-like) YP_001092514.1 PFAM: malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: sfr:Sfri_3757 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) YP_001092515.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_001092516.1 KEGG: sdn:Sden_3351 conserved hypothetical biogenesis protein MshI YP_001092517.1 PFAM: Fimbrial assembly family protein; KEGG: she:Shewmr4_3489 hypothetical protein YP_001092518.1 KEGG: son:SO4114 MSHA biogenesis protein MshJ YP_001092519.1 KEGG: she:Shewmr4_3487 MSHA biogenesis protein MshK YP_001092520.1 TIGRFAM: pilus (MSHA type) biogenesis protein MshL; PFAM: type II and III secretion system protein; Secretin domain protein; Secretin/TonB, short N-terminal domain; KEGG: she:Shewmr4_3486 pilus (MSHA type) biogenesis protein MshL YP_001092521.1 KEGG: she:Shewmr4_3485 MSHA biogenesis protein MshM YP_001092522.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0468 tetratricopeptide TPR_2 repeat protein YP_001092523.1 PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_0469 type II secretion system protein E YP_001092524.1 PFAM: type II secretion system protein; KEGG: son:SO4108 MSHA biogenesis protein MshG YP_001092525.1 KEGG: shm:Shewmr7_0471 hypothetical protein YP_001092526.1 KEGG: shm:Shewmr7_0472 methylation site containing protein YP_001092527.1 KEGG: she:Shewmr4_3296 methylation site containing protein YP_001092528.1 KEGG: she:Shewmr4_3479 methylation site containing protein YP_001092529.1 KEGG: son:SO4104 MSHA pilin protein MshC YP_001092530.1 KEGG: she:Shewmr4_3476 methylation site containing protein YP_001092531.1 KEGG: sfr:Sfri_3741 methylation site containing protein YP_001092532.1 KEGG: sfr:Sfri_3740 MSHA biogenesis protein MshP YP_001092533.1 KEGG: she:Shewmr4_3473 MSHA biogenesis protein MshQ YP_001092534.1 functions in MreBCD complex in some organisms YP_001092535.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_001092536.1 PFAM: Rod shape-determining protein MreD; KEGG: sfr:Sfri_3736 rod shape-determining protein MreD YP_001092537.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: sdn:Sden_3331 maf protein YP_001092538.1 involved in the processing of the 5'end of 16S rRNA YP_001092539.1 KEGG: she:Shewmr4_3467 hypothetical protein YP_001092540.1 PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: son:SO4092 hydrolase, carbon-nitrogen family YP_001092541.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: shm:Shewmr7_0486 peptidase U62, modulator of DNA gyrase YP_001092542.1 PFAM: outer membrane efflux protein; KEGG: shm:Shewmr7_0487 outer membrane efflux protein YP_001092543.1 PFAM: secretion protein HlyD family protein; KEGG: son:SO4089 HlyD family secretion protein YP_001092544.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3462 ABC-2 type transporter YP_001092545.1 PFAM: ABC-2 type transporter; KEGG: she:Shewmr4_3461 ABC-2 type transporter YP_001092546.1 PFAM: protein of unknown function DUF615; KEGG: sdn:Sden_3068 protein of unknown function DUF615 YP_001092547.1 PFAM: peptidase U62, modulator of DNA gyrase; KEGG: sfr:Sfri_3721 peptidase U62, modulator of DNA gyrase YP_001092548.1 PFAM: regulatory protein, ArsR; KEGG: she:Shewmr4_0532 transcriptional regulator, ArsR family YP_001092549.1 TIGRFAM: arsenical-resistance protein; PFAM: Bile acid:sodium symporter; KEGG: sde:Sde_3779 arsenical pump membrane protein, putative YP_001092550.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate YP_001092551.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0539 transporter, putative YP_001092552.1 PFAM: PspC domain protein; KEGG: nfa:nfa8710 hypothetical protein YP_001092553.1 KEGG: ilo:IL0802 hypothetical protein YP_001092554.1 PFAM: regulatory protein, MerR; KEGG: ilo:IL0801 transcriptional regulator, MerR family YP_001092555.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: sdn:Sden_0649 amino acid carrier protein YP_001092556.1 PFAM: ABC-2 type transporter; KEGG: sfr:Sfri_3539 ABC-2 type transporter YP_001092557.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sfr:Sfri_3538 ABC transporter-related protein YP_001092558.1 KEGG: sfr:Sfri_3537 hypothetical protein YP_001092559.1 KEGG: shm:Shewmr7_3488 hypothetical protein YP_001092560.1 KEGG: she:Shewmr4_0547 hypothetical protein YP_001092561.1 PFAM: histone family protein DNA-binding protein; KEGG: sfr:Sfri_3532 histone family protein DNA-binding protein YP_001092562.1 KEGG: son:SO0550 hypothetical protein YP_001092563.1 KEGG: shm:Shewmr7_3479 hypothetical protein YP_001092565.1 KEGG: shm:Shewmr7_3477 hypothetical protein YP_001092566.1 KEGG: son:SO0554 hypothetical protein YP_001092567.1 PFAM: GGDEF domain containing protein; CBS domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3475 diguanylate cyclase/phosphodiesterase YP_001092568.1 KEGG: shm:Shewmr7_3474 hypothetical protein YP_001092569.1 PFAM: GumN family protein; KEGG: son:SO0557 hypothetical protein YP_001092570.1 PFAM: CheD family protein; KEGG: sde:Sde_3103 CheD, stimulates methylation of MCP proteins YP_001092571.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3472 methyltransferase type 11 YP_001092572.1 PFAM: MaoC domain protein dehydratase; KEGG: shm:Shewmr7_3471 MaoC domain protein dehydratase YP_001092573.1 PFAM: aldo/keto reductase; KEGG: she:Shewmr4_0560 aldo/keto reductase YP_001092574.1 catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate YP_001092575.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_3468 MscS mechanosensitive ion channel YP_001092576.1 KEGG: she:Shewmr4_0563 hypothetical protein YP_001092577.1 KEGG: sfr:Sfri_3518 hypothetical protein YP_001092578.1 KEGG: shm:Shewmr7_3464 hypothetical protein YP_001092579.1 PFAM: periplasmic solute binding protein; KEGG: shm:Shewmr7_3463 periplasmic solute binding protein YP_001092580.1 PFAM: ABC-3 protein; KEGG: shm:Shewmr7_3462 ABC-3 protein YP_001092581.1 KEGG: son:SO0567 1-acyl-sn-glycerol-3-phosphate acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; PFAM: phospholipid/glycerol acyltransferase YP_001092582.1 PFAM: protein of unknown function DUF1260; KEGG: sfr:Sfri_3513 protein of unknown function DUF1260 YP_001092583.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sfr:Sfri_3512 diguanylate cyclase YP_001092584.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_3458 response regulator receiver protein YP_001092585.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001092586.1 PFAM: uncharacterized protein UPF0114; KEGG: cps:CPS_1797 hypothetical protein YP_001092587.1 KEGG: she:Shewmr4_0574 hypothetical protein YP_001092588.1 transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA YP_001092589.1 PFAM: PhoH family protein; SMART: AAA ATPase; Nucleotide binding protein, PINc; KEGG: son:SO0576 PhoH family protein YP_001092590.1 KEGG: she:Shewmr4_0577 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001092591.1 KEGG: sfr:Sfri_3501 hypothetical protein YP_001092594.1 KEGG: she:Shewmr4_3425 hypothetical protein YP_001092596.1 KEGG: rba:RB544 hypothetical protein YP_001092597.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_0550 acriflavin resistance protein YP_001092598.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3401 efflux transporter, RND family, MFP subunit YP_001092599.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_1434 transcriptional regulator, LysR family protein YP_001092600.1 PFAM: pentapeptide repeat protein; KEGG: ppr:PBPRB0125 hypothetical protein YP_001092601.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: she:Shewmr4_3399 MATE efflux family protein YP_001092602.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_001092603.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001092605.1 KEGG: vfi:VF2040 hypothetical protein YP_001092606.1 KEGG: vfi:VF2039 hypothetical protein YP_001092607.1 PFAM: protein of unknown function DUF88; KEGG: sfr:Sfri_3658 protein of unknown function DUF88 YP_001092609.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0557 transcriptional regulator, XRE family YP_001092610.1 PFAM: HipA domain protein; KEGG: she:Shewmr4_3395 HipA domain protein YP_001092611.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: lpp:lpp1174 hypothetical protein YP_001092612.1 KEGG: sfr:Sfri_3654 hypothetical protein YP_001092613.1 KEGG: sfr:Sfri_2138 hypothetical protein YP_001092614.1 KEGG: sfr:Sfri_2137 hypothetical protein YP_001092616.1 PFAM: Cold-shock protein, DNA-binding; Excalibur domain protein; SMART: Cold shock protein; KEGG: sfr:Sfri_3647 cold-shock DNA-binding domain protein YP_001092617.1 PFAM: permease; KEGG: sfr:Sfri_1725 permease YP_001092618.1 TIGRFAM: redox-active disulfide protein 2; KEGG: mbu:Mbur_0943 redox-active disulfide protein 2 YP_001092619.1 PFAM: regulatory protein, ArsR; KEGG: dps:DP0944 similar to ArsR-family transcription regulator YP_001092621.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: shm:Shewmr7_3813 peptidase S9, prolyl oligopeptidase active site domain protein YP_001092622.1 KEGG: son:SO0721 hypothetical protein YP_001092623.1 TIGRFAM: hemerythrin-like metal-binding protein; PFAM: chemotaxis sensory transducer; Hemerythrin HHE cation binding domain protein; KEGG: son:SO3890 methyl-accepting chemotaxis protein YP_001092624.1 KEGG: son:SO0720 hypothetical protein YP_001092626.1 KEGG: she:Shewmr4_3378 hypothetical protein YP_001092627.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: shm:Shewmr7_3308 amino acid carrier protein YP_001092628.1 putative role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_001092629.1 KEGG: son:SO0492 hypothetical flavoprotein oxygenase YP_001092630.1 KEGG: ilo:IL1431 Xaa-Pro aminopeptidase family enzyme YP_001092631.1 KEGG: dps:DP1291 hypothetical protein YP_001092632.1 PFAM: protein of unknown function DUF134; KEGG: son:SO0727 hypothetical protein YP_001092633.1 KEGG: son:SO0728 hypothetical protein YP_001092634.1 KEGG: shm:Shewmr7_0578 thioredoxin domain YP_001092635.1 PFAM: NnrS family protein; KEGG: sfr:Sfri_3037 NnrS family protein YP_001092636.1 PFAM: cytochrome c552; KEGG: sfr:Sfri_3036 nitrite reductase (cytochrome; ammonia-forming) YP_001092637.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4154 transcriptional regulator, LysR family YP_001092638.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: son:SO4153 N-ethylmaleimide reductase, putative YP_001092639.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: she:Shewmr4_3514 sulphate transporter YP_001092640.1 KEGG: vpa:VPA1145 hypothetical protein YP_001092641.1 TIGRFAM: putative outer membrane adhesin like proteiin; KEGG: son:SO4149 RTX toxin, putative YP_001092642.1 TIGRFAM: type I secretion membrane fusion protein, HlyD family; PFAM: secretion protein HlyD family protein; KEGG: son:SO4148 HlyD family secretion protein YP_001092643.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4147 ABC transporter, ATP-binding/permease protein YP_001092644.1 PFAM: ABC transporter-related protein; KEGG: son:SO4146 toxin secretion ABC transporter protein, HlyB family YP_001092645.1 KEGG: shm:Shewmr7_0439 cytochrome c, putative YP_001092646.1 KEGG: son:SO4143 hypothetical protein YP_001092647.1 KEGG: shm:Shewmr7_0441 cytochrome c family protein YP_001092648.1 KEGG: eca:ECA0549 putative plasmid transfer protein YP_001092649.1 PFAM: protein of unknown function DUF81; KEGG: son:SO4058 hypothetical protein YP_001092650.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_001092651.1 KEGG: she:Shewmr4_3439 O-succinylhomoserine (thiol)-lyase; TIGRFAM: O-succinylhomoserine (thiol)-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001092652.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001092653.1 MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor YP_001092654.1 KEGG: shm:Shewmr7_0519 cytochrome c family protein YP_001092655.1 PFAM: cytochrome c, class I; KEGG: son:SO4047 cytochrome c family protein YP_001092656.1 KEGG: sdn:Sden_0645 hypothetical protein YP_001092657.1 KEGG: sfr:Sfri_3540 hypothetical protein YP_001092658.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfr:Sfri_3249 Sel1 domain protein repeat-containing protein YP_001092659.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfr:Sfri_3249 Sel1 domain protein repeat-containing protein YP_001092660.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfr:Sfri_3249 Sel1 domain protein repeat-containing protein YP_001092661.1 PFAM: FAD dependent oxidoreductase; KEGG: pae:PA5145 hypothetical protein YP_001092662.1 PFAM: helicase domain protein; DbpA, RNA-binding domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_0528 DEAD/DEAH box helicase domain protein YP_001092663.1 PFAM: peptidase M28; KEGG: shm:Shewmr7_0529 peptidase M28 YP_001092664.1 TIGRFAM: excinuclease ABC, A subunit; PFAM: ABC transporter-related protein; KEGG: shm:Shewmr7_0531 excinuclease ABC, A subunit YP_001092665.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3420 major facilitator superfamily MFS_1 YP_001092666.1 TIGRFAM: single-strand binding protein; PFAM: single-strand binding protein/Primosomal replication protein n; KEGG: sfr:Sfri_3710 single-strand binding protein YP_001092667.1 TIGRFAM: TIM-barrel protein, yjbN family; PFAM: dihydrouridine synthase, DuS; KEGG: shm:Shewmr7_0746 TIM-barrel protein, YjbN family YP_001092668.1 KEGG: shm:Shewmr7_0747 hypothetical protein YP_001092669.1 PFAM: PspC domain protein; KEGG: she:Shewmr4_3241 phage shock protein C, PspC YP_001092671.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_0749 enoyl-CoA hydratase/isomerase YP_001092672.1 PFAM: protein of unknown function DUF461; KEGG: shm:Shewmr7_0750 protein of unknown function DUF461 YP_001092673.1 KEGG: son:SO3906 hypothetical protein YP_001092674.1 KEGG: she:Shewmr4_3237 hypothetical protein YP_001092675.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_001092676.1 PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_3235 nucleoside diphosphate pyrophosphatase YP_001092677.1 PFAM: protein of unknown function DUF1249; KEGG: she:Shewmr4_3234 protein of unknown function DUF1249 YP_001092678.1 PFAM: metallophosphoesterase; Calcineurin phosphoesterase C-terminal domain protein; KEGG: she:Shewmr4_3233 calcineurin phosphoesterase C-terminal domain protein YP_001092679.1 PFAM: protein of unknown function UPF0227; KEGG: she:Shewmr4_3232 protein of unknown function UPF0227 YP_001092680.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001092681.1 KEGG: shm:Shewmr7_0759 L-sorbosone dehydrogenase, putative YP_001092682.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_001092683.1 PFAM: BFD domain protein [2Fe-2S]-binding domain protein; KEGG: sdn:Sden_3217 BFD-like (2Fe-2S)-binding region YP_001092684.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: she:Shewmr4_0584 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding YP_001092685.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: shm:Shewmr7_3444 glycerophosphoryl diester phosphodiesterase YP_001092686.1 PFAM: MscS Mechanosensitive ion channel; KEGG: she:Shewmr4_0587 MscS mechanosensitive ion channel YP_001092687.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_3442 protein of unknown function DUF6, transmembrane YP_001092688.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_001092689.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_001092690.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_001092691.1 KEGG: son:SO0595 hypothetical protein YP_001092692.1 TIGRFAM: carbohydrate kinase, YjeF-related protein; PFAM: protein of unknown function UPF0031; YjeF-family N-terminal domain protein; KEGG: she:Shewmr4_0593 carbohydrate kinase, YjeF-related protein YP_001092693.1 PFAM: protein of unknown function UPF0079; KEGG: she:Shewmr4_0594 protein of unknown function UPF0079 YP_001092694.1 PFAM: Peptidoglycan-binding LysM; cell wall hydrolase/autolysin; KEGG: she:Shewmr4_0595 N-acetylmuramoyl-L-alanine amidase YP_001092695.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_001092696.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_001092697.1 TIGRFAM: RNA chaperone Hfq; PFAM: Like-Sm ribonucleoprotein, core; KEGG: shm:Shewmr7_3432 RNA chaperone Hfq YP_001092698.1 PFAM: GTP-binding protein, HSR1-related; KEGG: son:SO0604 GTP-binding protein HflX YP_001092699.1 TIGRFAM: HflK protein; PFAM: band 7 protein; KEGG: shm:Shewmr7_3430 HflK protein YP_001092700.1 TIGRFAM: HflC protein; PFAM: band 7 protein; KEGG: shm:Shewmr7_3429 HflC protein YP_001092701.1 TIGRFAM: ubiquinol-cytochrome c reductase, iron-sulfur subunit; PFAM: Rieske [2Fe-2S] domain protein; KEGG: shm:Shewmr7_3428 ubiquinol-cytochrome c reductase, iron-sulfur subunit YP_001092702.1 PFAM: Cytochrome b/b6, N-terminal domain; Cytochrome b/b6, C-terminal domain; KEGG: shm:Shewmr7_3427 cytochrome b/b6, N-terminal domain protein YP_001092703.1 PFAM: cytochrome c1; KEGG: shm:Shewmr7_3426 cytochrome c1 YP_001092704.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_001092705.1 PFAM: Stringent starvation protein B; KEGG: shm:Shewmr7_3424 stringent starvation protein B YP_001092706.1 TIGRFAM: glutamine amidotransferase of anthranilate synthase; PFAM: glutamine amidotransferase class-I; KEGG: son:SO0613 para-aminobenzoate synthase glutamine amidotransferase, component II YP_001092707.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: she:Shewmr4_0608 peptidase S9, prolyl oligopeptidase active site domain protein YP_001092708.1 PFAM: HDOD; KEGG: son:SO0615 hypothetical protein YP_001092709.1 DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate YP_001092710.1 PFAM: arginine N-succinyltransferase beta subunit; KEGG: son:SO0618 arginine N-succinyltransferase YP_001092711.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_001092712.1 KEGG: shm:Shewmr7_3416 hypothetical protein YP_001092713.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO0621 sensor histidine kinase YP_001092714.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3414 two component transcriptional regulator, winged helix family YP_001092715.1 KEGG: shm:Shewmr7_3413 hypothetical protein YP_001092716.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_001092717.1 KEGG: sfr:Sfri_3291 tetratricopeptide TPR_2 repeat protein YP_001092718.1 PFAM: phosphoribulokinase/uridine kinase; KEGG: son:SO0878 phosphoribulokinase YP_001092719.1 PFAM: protein of unknown function UPF0270; KEGG: sdn:Sden_3187 protein of unknown function UPF0270 YP_001092720.1 PFAM: alpha/beta hydrolase fold; KEGG: she:Shewmr4_0736 alpha/beta hydrolase fold YP_001092721.1 KEGG: son:SO0881 hypothetical protein YP_001092722.1 PFAM: glucose-methanol-choline oxidoreductase; GMC oxidoreductase; KEGG: son:SO0882 oxidoreductase, GMC family YP_001092723.1 KEGG: sfr:Sfri_3285 hypothetical protein YP_001092724.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3281 ABC transporter-related protein YP_001092725.1 KEGG: sdn:Sden_3177 hypothetical protein YP_001092727.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: cps:CPS_1439 methyl-accepting chemotaxis protein YP_001092728.1 PFAM: major facilitator superfamily MFS_1; KEGG: bth:BT0821 putative permease YP_001092729.1 exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA YP_001092730.1 KEGG: btk:BT9727_0331 hypothetical protein YP_001092732.1 KEGG: net:Neut_1865 hypothetical protein YP_001092733.1 PFAM: Methyltransferase type 12; KEGG: hch:HCH_01556 SAM-dependent methyltransferase YP_001092734.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: she:Shewmr4_0739 glutathione-dependent formaldehyde-activating, GFA YP_001092735.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3783 ATP-dependent RNA helicase, DEAD box family YP_001092736.1 KEGG: sfr:Sfri_0822 hypothetical protein YP_001092737.1 PFAM: Polysulphide reductase, NrfD; KEGG: she:Shewmr4_3442 polysulphide reductase, NrfD YP_001092738.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_0508 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001092739.1 PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_3444 twin-arginine translocation pathway signal YP_001092740.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: son:SO4157 DNA-binding response regulator YP_001092741.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4155 sensor histidine kinase YP_001092744.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001092745.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_001092746.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain YP_001092747.1 SMART: SH3 domain protein domain protein; KEGG: shm:Shewmr7_0851 SH3 domain protein domain protein YP_001092748.1 PFAM: phosphate transporter; KEGG: sdn:Sden_0691 phosphate transporter YP_001092749.1 PFAM: protein of unknown function DUF47; KEGG: sfr:Sfri_0565 protein of unknown function DUF47 YP_001092750.1 PFAM: adenylate cyclase; KEGG: she:Shewmr4_3118 adenylate cyclase YP_001092751.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: sfr:Sfri_3269 ion transport 2 domain protein YP_001092752.1 KEGG: shm:Shewmr7_0856 hypothetical protein YP_001092753.1 KEGG: son:SO3766 hypothetical protein YP_001092754.1 PFAM: PspA/IM30 family protein; KEGG: son:SO3765 hypothetical protein YP_001092755.1 KEGG: shm:Shewmr7_0859 hypothetical protein YP_001092756.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_001092757.1 KEGG: sfr:Sfri_3263 protein of unknown function DUF350 YP_001092758.1 KEGG: she:Shewmr4_3110 hypothetical protein YP_001092759.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_001092760.1 SMART: extracellular solute-binding protein, family 3; KEGG: vvy:VV1499 hypothetical protein YP_001092761.1 PFAM: conserved hypothetical protein 245; KEGG: vpa:VP1159 putative ABC transport system permease protein YP_001092762.1 PFAM: AFG1-family ATPase; KEGG: shm:Shewmr7_0870 AFG1-family ATPase YP_001092763.1 PFAM: OmpA/MotB domain protein; KEGG: sfr:Sfri_0594 OmpA/MotB domain protein YP_001092764.1 KEGG: sdn:Sden_2001 hypothetical protein YP_001092765.1 KEGG: she:Shewmr4_3460 hypothetical protein YP_001092768.1 KEGG: sfr:Sfri_0597 hypothetical protein YP_001092769.1 PFAM: cell surface receptor IPT/TIG domain protein; KEGG: hwa:HQ3601A cell surface calcium-binding acidic-repeat protein YP_001092770.1 KEGG: bxe:Bxe_B2925 hypothetical protein YP_001092771.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: mba:Mbar_A2604 TPR repeat YP_001092772.1 PFAM: protein of unknown function DUF192; KEGG: bba:Bd0471 putative secreted protein YP_001092773.1 PFAM: type II secretion system protein; KEGG: bxe:Bxe_B2923 putative type II secretion system protein F YP_001092774.1 PFAM: type II secretion system protein; KEGG: bxe:Bxe_B2922 putative type II secretion system protein F YP_001092775.1 PFAM: Forkhead-associated protein; type II secretion system protein E; KEGG: bxe:Bxe_B2921 type II/IV secretion system protein E YP_001092776.1 PFAM: type II and III secretion system protein; KEGG: bxe:Bxe_B2920 putative type II and III secretion system outermembrane protein, secretin YP_001092777.1 PFAM: SAF domain; KEGG: bxe:Bxe_B2919 putative Flp pilus assembly CpaB YP_001092779.1 KEGG: bxe:Bxe_B2917 hypothetical protein YP_001092780.1 KEGG: bxe:Bxe_B2916 hypothetical protein YP_001092781.1 KEGG: ilo:IL0909 uncharacterized secreted protein YP_001092782.1 KEGG: ilo:IL0910 Flp/Fap pilin homolog YP_001092783.1 KEGG: ilo:IL0910 Flp/Fap pilin homolog YP_001092784.1 PFAM: regulatory protein, LuxR; KEGG: sfr:Sfri_0602 transcriptional regulator, LuxR family protein YP_001092785.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_3094 peptidase M16 domain protein YP_001092786.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_3093 peptidase M16 domain protein YP_001092787.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_001092788.1 KEGG: shm:Shewmr7_0883 putative nitric oxide reductase (subunit B) transmembrane protein YP_001092789.1 TIGRFAM: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; PFAM: lipid A biosynthesis acyltransferase; KEGG: sfr:Sfri_3201 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase YP_001092790.1 catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose YP_001092791.1 KEGG: son:SO3744 hypothetical protein YP_001092792.1 KEGG: sfr:Sfri_3497 hypothetical protein YP_001092793.1 PFAM: NAD(P) transhydrogenase, beta subunit; KEGG: abo:ABO_1327 pyridine nucleotide transhydrogenase, B subunit YP_001092794.1 KEGG: abo:ABO_1328 oxidoreductase YP_001092795.1 PFAM: alanine dehydrogenase/PNT domain protein; KEGG: abo:ABO_1329 pyridine nucleotide transhydrogenase A subunit YP_001092796.1 TIGRFAM: sulfite reductase [NADPH] flavoprotein, alpha chain; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; FAD-binding domain protein; flavodoxin/nitric oxide synthase; KEGG: son:SO3738 sulfite reductase (NADPH) flavoprotein alpha-component YP_001092797.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_001092798.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_001092799.1 KEGG: son:SO3733 hypothetical protein YP_001092800.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cps:CPS_2601 antioxidant, AhpC/Tsa family YP_001092801.1 KEGG: she:Shewmr4_3075 hypothetical protein YP_001092802.1 PFAM: phospholipase A1; KEGG: sdn:Sden_0955 phospholipase A1 YP_001092803.1 TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: shm:Shewmr7_0899 uroporphyrin-III C-methyltransferase YP_001092804.1 KEGG: shm:Shewmr7_0904 hypothetical protein YP_001092805.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3067 major facilitator superfamily MFS_1 YP_001092806.1 KEGG: sfr:Sfri_0810 hypothetical protein YP_001092807.1 KEGG: sfr:Sfri_0811 putative lipoprotein YP_001092808.1 PFAM: protein of unknown function DUF1111; KEGG: sdn:Sden_0723 protein of unknown function DUF1111 YP_001092809.1 KEGG: shm:Shewmr7_0906 protoporphyrinogen oxidase YP_001092810.1 KEGG: she:Shewmr4_3065 hypothetical protein YP_001092811.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pfl:PFL_5747 transcriptional regulator, LysR family YP_001092812.1 KEGG: vch:VCA0877 hydrolase, putative YP_001092813.1 KEGG: vvu:VV20703 permease of the major facilitator superfamily YP_001092814.1 PFAM: secretion protein HlyD family protein; KEGG: vvu:VV13195 multidrug resistance efflux pump YP_001092816.1 KEGG: deh:cbdb_A1523 hypothetical membrane protein YP_001092817.1 PFAM: DSBA oxidoreductase; KEGG: shm:Shewmr7_0909 DsbA oxidoreductase YP_001092818.1 PFAM: heat shock protein DnaJ domain protein; KEGG: sdn:Sden_0724 heat shock protein DnaJ-like protein YP_001092819.1 catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive YP_001092820.1 KEGG: son:SO1045 hypothetical protein YP_001092821.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_0969 endonuclease/exonuclease/phosphatase YP_001092822.1 PFAM: protein of unknown function UPF0118; KEGG: ppr:PBPRA1562 hypothetical protein YP_001092823.1 KEGG: shm:Shewmr7_1015 hypothetical protein YP_001092825.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: cps:CPS_2587 membrane protein YP_001092826.1 PFAM: protein of unknown function DUF331; KEGG: shm:Shewmr7_0498 protein of unknown function DUF331 YP_001092827.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_001092828.1 Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific YP_001092829.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1936 Na+/H+ antiporter NhaC YP_001092830.1 KEGG: shm:Shewmr7_3245 Na+/H+ antiporter YP_001092831.1 PFAM: Pirin domain protein domain protein; Pirin domain protein; KEGG: shm:Shewmr7_3276 pirin domain protein domain protein YP_001092832.1 KEGG: hch:HCH_04210 hypothetical protein YP_001092833.1 PFAM: Rhomboid family protein; KEGG: jan:Jann_3255 rhomboid-like protein YP_001092834.1 PFAM: response regulator receiver; KEGG: pha:PSHAa1150 response regulator CheB (receptor modification enzyme, protein-glutamate methylesterase) YP_001092837.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: son:SO0510 oxidoreductase, short-chain dehydrogenase/reductase family YP_001092838.1 PFAM: YbaK/prolyl-tRNA synthetase associated region; KEGG: vpa:VPA0766 hypothetical protein YP_001092839.1 KEGG: shm:Shewmr7_2638 hypothetical protein YP_001092840.1 KEGG: sfr:Sfri_3122 catalase/peroxidase HPI; TIGRFAM: catalase/peroxidase HPI; PFAM: Haem peroxidase YP_001092841.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_001092842.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO1031 alpha-ribazole-5'-phosphate phosphatase, putative YP_001092843.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0840 ABC transporter-related protein YP_001092844.1 PFAM: transport system permease protein; KEGG: she:Shewmr4_0841 transport system permease protein YP_001092845.1 catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole YP_001092846.1 TIGRFAM: cobalamin 5'-phosphate synthase; PFAM: cobalamin-5-phosphate synthase CobS; KEGG: sfr:Sfri_0877 cobalamin 5'-phosphate synthase YP_001092847.1 PFAM: cobalbumin biosynthesis enzyme; KEGG: son:SO1037 cobinamide kinase/cobinamide phosphate guanylyltransferase YP_001092848.1 catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation YP_001092849.1 catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide YP_001092850.1 PFAM: periplasmic binding protein; KEGG: she:Shewmr4_0848 periplasmic binding protein YP_001092851.1 KEGG: son:SO3708 hypothetical protein YP_001092852.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sfr:Sfri_0897 efflux transporter, RND family, MFP subunit YP_001092854.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3159 ABC transporter-related protein YP_001092855.1 PFAM: protein of unknown function DUF214; KEGG: sfr:Sfri_0899 protein of unknown function DUF214 YP_001092856.1 PFAM: protein of unknown function DUF214; KEGG: sdn:Sden_2848 protein of unknown function DUF214 YP_001092857.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_3156 two component, sigma54 specific, transcriptional regulator, fis family YP_001092858.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3155 periplasmic sensor signal transduction histidine kinase YP_001092859.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_001092860.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ppr:PBPRA1421 putative NADH oxidase YP_001092861.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: ppr:PBPRA1422 conserved hypothetical protein YP_001092862.1 PFAM: protein of unknown function DUF395, YeeE/YedE; KEGG: pat:Patl_2106 protein of unknown function DUF395, YeeE/YedE YP_001092863.1 KEGG: pfo:Pfl_3508 putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein YP_001092864.1 KEGG: shm:Shewmr7_3361 hypothetical protein YP_001092865.1 PFAM: Fe-S metabolism associated SufE; KEGG: sfr:Sfri_3182 Fe-S metabolism associated SufE YP_001092866.1 TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase, class V; KEGG: son:SO3789 aminotransferase, class V YP_001092867.1 PFAM: aldo/keto reductase; KEGG: shm:Shewmr7_3273 aldo/keto reductase YP_001092868.1 PFAM: GCN5-related N-acetyltransferase; regulatory protein, MarR; KEGG: shm:Shewmr7_3265 transcriptional regulator, MarR family with acetyltransferase activity YP_001092869.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_001092870.1 PFAM: aromatic amino acid permease; KEGG: shm:Shewmr7_3262 amino acid transporter, transmembrane YP_001092871.1 KEGG: ecp:ECP_1757 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001092872.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0762 GCN5-related N-acetyltransferase YP_001092873.1 KEGG: son:SO0921 hypothetical protein YP_001092874.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3259 sodium:dicarboxylate symporter YP_001092875.1 PFAM: protein of unknown function DUF306, Meta and HslJ; KEGG: shm:Shewmr7_3258 protein of unknown function DUF306, MetA and HslJ YP_001092876.1 KEGG: she:Shewmr4_0766 hypothetical protein YP_001092877.1 PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_3256 GGDEF domain protein YP_001092878.1 KEGG: shm:Shewmr7_3256 GGDEF domain protein YP_001092879.1 KEGG: son:SO0926 acetyltransferase, GNAT family YP_001092880.1 KEGG: sfr:Sfri_0644 hypothetical protein YP_001092881.1 KEGG: sfr:Sfri_3020 hypothetical protein YP_001092882.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_001092883.1 catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase YP_001092884.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_001092885.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_001092886.1 class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis YP_001092887.1 PFAM: protein of unknown function DUF481; KEGG: shm:Shewmr7_3246 protein of unknown function DUF481 YP_001092888.1 KEGG: she:Shewmr4_0779 response regulator receiver protein YP_001092889.1 KEGG: shm:Shewmr7_3242 hypothetical protein YP_001092890.1 KEGG: sfr:Sfri_3633 cytochrome c, putative YP_001092891.1 PFAM: transcriptional regulator domain protein; KEGG: son:SO0940 transcriptional regulator-related protein YP_001092892.1 KEGG: shm:Shewmr7_3239 hypothetical protein YP_001092893.1 KEGG: son:SO0942 hypothetical protein YP_001092894.1 PFAM: PAS fold domain protein; SMART: PAS domain containing protein; KEGG: shm:Shewmr7_3237 putative PAS/PAC sensor protein YP_001092895.1 PFAM: Radical SAM domain protein; KEGG: shm:Shewmr7_3236 radical SAM domain protein YP_001092896.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3235 acriflavin resistance protein YP_001092897.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_0789 efflux transporter, RND family, MFP subunit YP_001092898.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_001092899.1 PFAM: methyltransferase small; KEGG: she:Shewmr4_0793 methyltransferase small YP_001092900.1 PFAM: branched-chain amino acid transport system II carrier protein; KEGG: sfr:Sfri_0662 branched-chain amino acid transport system II carrier protein YP_001092901.1 TIGRFAM: tyrosine recombinase XerD; PFAM: phage integrase family protein; phage integrase domain protein SAM domain protein; KEGG: she:Shewmr4_0795 tyrosine recombinase XerD YP_001092902.1 KEGG: son:SO0951 thiol:disulfide interchange protein DsbC YP_001092903.1 TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: shm:Shewmr7_3226 single-stranded-DNA-specific exonuclease RecJ YP_001092904.1 catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate YP_001092905.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9B, dipeptidylpeptidase IV domain protein; KEGG: shm:Shewmr7_3372 peptidase S9B, dipeptidylpeptidase IV domain protein YP_001092906.1 PFAM: regulatory protein, TetR; KEGG: vpa:VPA1299 putative transcriptional regulator YP_001092907.1 PFAM: bifunctional deaminase-reductase domain protein; KEGG: vpa:VPA1300 hypothetical protein YP_001092908.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3371 two component transcriptional regulator, winged helix family YP_001092909.1 KEGG: shm:Shewmr7_3370 hypothetical protein YP_001092910.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_001092911.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: shm:Shewmr7_3368 succinylglutamate desuccinylase/aspartoacylase YP_001092912.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sfr:Sfri_0513 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001092913.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_001092914.1 PFAM: pseudouridine synthase; KEGG: she:Shewmr4_3139 pseudouridylate synthase YP_001092915.1 KEGG: shm:Shewmr7_3212 hypothetical protein YP_001092916.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_0810 methyltransferase type 12 YP_001092917.1 KEGG: she:Shewmr4_0809 hypothetical protein YP_001092918.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3216 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001092919.1 PFAM: dienelactone hydrolase; KEGG: she:Shewmr4_0806 dienelactone hydrolase YP_001092920.1 PFAM: Mg2+ transporter protein, CorA family protein; KEGG: sfr:Sfri_0943 Mg2 transporter protein, CorA family protein YP_001092921.1 KEGG: shm:Shewmr7_3219 hypothetical protein YP_001092922.1 PFAM: Spermine synthase; KEGG: shm:Shewmr7_3220 spermine synthase YP_001092923.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_3222 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001092924.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0800 FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001092925.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: spt:SPA1005 hypothetical protein YP_001092926.1 KEGG: cps:CPS_4848 hypothetical protein YP_001092927.1 KEGG: sdn:Sden_3162 hypothetical protein YP_001092928.1 KEGG: shm:Shewmr7_3210 hypothetical protein YP_001092930.1 PFAM: regulatory protein, MarR; KEGG: sfr:Sfri_0578 transcriptional regulator, MarR family protein YP_001092931.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_3207 FAD dependent oxidoreductase YP_001092932.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_001092933.1 TIGRFAM: chromate transporter, chromate ion transporter (CHR) family; PFAM: Chromate transporter; KEGG: sfr:Sfri_0580 chromate transporter, chromate ion transporter (CHR) family protein YP_001092934.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_0818 periplasmic sensor signal transduction histidine kinase YP_001092935.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3204 two component transcriptional regulator, winged helix family YP_001092936.1 KEGG: she:Shewmr4_0820 hypothetical protein YP_001092937.1 PFAM: MltA-interacting MipA family protein; KEGG: shm:Shewmr7_3202 MltA-interacting MipA family protein YP_001092938.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: shm:Shewmr7_3201 LPXTG-motif cell wall anchor domain YP_001092939.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_0630 methyl-accepting chemotaxis sensory transducer YP_001092940.1 TIGRFAM: formate dehydrogenase, alpha subunit; PFAM: ferredoxin; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; molybdopterin oxidoreductase Fe4S4 region; KEGG: she:Shewmr4_0825 formate dehydrogenase, alpha subunit YP_001092941.1 PFAM: pentapeptide repeat protein; Ion transport 2 domain protein,; KEGG: vvy:VV0782 putative potassium channel protein YP_001092942.1 TIGRFAM: peptide chain release factor 2; PFAM: Class I peptide chain release factor; PCRF domain protein; KEGG: shm:Shewmr7_3197 peptide chain release factor 2 YP_001092943.1 class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 YP_001092944.1 KEGG: shm:Shewmr7_1231 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001092945.1 PFAM: pseudouridine synthase; KEGG: cps:CPS_1154 RNA pseudouridine synthase family protein YP_001092946.1 TIGRFAM: glucosamine-6-phosphate isomerase; PFAM: glucosamine/galactosamine-6-phosphate isomerase; KEGG: hch:HCH_06984 glucosamine-6-phosphate isomerase YP_001092947.1 KEGG: sdn:Sden_0648 hypothetical protein YP_001092948.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: mbu:Mbur_1476 cupin family protein YP_001092949.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_0828 peptidase U32 YP_001092950.1 PFAM: protein of unknown function DUF1696; KEGG: shm:Shewmr7_0829 protein of unknown function DUF1696 YP_001092951.1 KEGG: she:Shewmr4_3134 hypothetical protein YP_001092952.1 KEGG: xac:XAC3907 mitomycin resistance protein YP_001092953.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: bte:BTH_II0577 hypothetical protein YP_001092954.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_0776 transcriptional regulator, LysR family protein YP_001092955.1 KEGG: shm:Shewmr7_0612 NAD-dependent epimerase/dehydratase YP_001092956.1 Catalyzes D-ribose 5-phosphate --> D-ribulose 5-phosphate in the nonoxidative branch of the pentose phosphate pathway YP_001092957.1 PFAM: protein of unknown function DUF808; KEGG: son:SO1151 hypothetical protein YP_001092958.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_2838 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001092959.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1046 transcriptional regulator, LysR family YP_001092960.1 PFAM: LrgA family protein; KEGG: she:Shewmr4_3050 LrgA family protein YP_001092961.1 PFAM: LrgB family protein; KEGG: she:Shewmr4_3049 LrgB family protein YP_001092962.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_0640 CBS domain containing membrane protein YP_001092963.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0641 twin-arginine translocation pathway signal YP_001092964.1 KEGG: shm:Shewmr7_0642 hypoxanthine-guanine phosphoribosyltransferase YP_001092966.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: she:Shewmr4_3040 aminopeptidase N YP_001092967.1 TIGRFAM: Prokaryotic membrane lipoprotein lipid attachment site; KEGG: shm:Shewmr7_0935 hypothetical protein YP_001092968.1 PFAM: Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: son:SO1061 TPR domain protein YP_001092969.1 PFAM: SlyX family protein; KEGG: sdn:Sden_2911 SlyX YP_001092970.1 PFAM: WD-40 repeat protein; KEGG: shm:Shewmr7_0939 WD-40 repeat protein YP_001092971.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_0940 peptidylprolyl isomerase, FKBP-type YP_001092972.1 PFAM: uncharacterized conserved protein UCP006287; KEGG: son:SO3983 hypothetical protein YP_001092973.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: shm:Shewmr7_3365 two component transcriptional regulator, LuxR family YP_001092974.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_3364 signal transduction histidine kinase, nitrate/nitrite-specific, NarQ YP_001092975.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_001092976.1 PFAM: isochorismatase hydrolase; KEGG: she:Shewmr4_3363 isochorismatase hydrolase YP_001092977.1 PFAM: nitrogen regulatory protein P-II; KEGG: sfr:Sfri_0623 nitrogen regulatory protein P-II YP_001092978.1 PFAM: Rh family protein/ammonium transporter; KEGG: shm:Shewmr7_0592 Rh family protein/ammonium transporter YP_001092979.1 KEGG: shm:Shewmr7_0593 hypothetical protein YP_001092980.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_0594 tetratricopeptide TPR_2 repeat protein YP_001092981.1 KEGG: sfr:Sfri_0627 ABC-type amino acid transport/signal transduction systems YP_001092982.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive YP_001092983.1 KEGG: shm:Shewmr7_0596 hypothetical protein YP_001092984.1 PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0597 ABC transporter-related protein YP_001092985.1 KEGG: shm:Shewmr7_0598 hypothetical protein YP_001092986.1 KEGG: son:SO0752 hypothetical protein YP_001092987.1 PFAM: Phosphoglycerate mutase; KEGG: son:SO0749 hypothetical protein YP_001092988.1 KEGG: son:SO0748 hypothetical protein YP_001092989.1 PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: son:SO0747 ferredoxin--NADP reductase YP_001092990.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: son:SO0746 glutathione S-transferase family protein YP_001092991.1 KEGG: son:SO0745 hypothetical protein YP_001092992.1 PFAM: extracellular solute-binding protein, family 1; KEGG: shm:Shewmr7_0606 extracellular solute-binding protein, family 1 YP_001092993.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sfr:Sfri_0637 binding-protein-dependent transport systems inner membrane component YP_001092994.1 PFAM: ABC transporter-related protein; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sfr:Sfri_0638 ABC transporter-related protein YP_001092995.1 TIGRFAM: Dyp-type peroxidase family; PFAM: Dyp-type peroxidase; KEGG: son:SO0740 melanin biosynthesis protein TyrA, putative YP_001092996.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: gvi:glr3306 hypothetical protein YP_001092997.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_001092998.1 oxidizes malate to oxaloacetate YP_001092999.1 PFAM: Polyprenyl synthetase; KEGG: son:SO3653 octaprenyl-diphosphate synthase YP_001093000.1 PFAM: ribosomal protein L21; KEGG: sfr:Sfri_3089 ribosomal protein L21 YP_001093001.1 involved in the peptidyltransferase reaction during translation YP_001093002.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_001093003.1 PFAM: protein of unknown function DUF1212; KEGG: son:SO3648 hypothetical protein YP_001093004.1 KEGG: son:SO3647 hypothetical protein YP_001093005.1 PFAM: dihydrofolate reductase region; KEGG: son:SO3646 dihydrofolate reductase YP_001093006.1 KEGG: sdn:Sden_2921 hypothetical protein YP_001093007.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: son:SO3642 methyl-accepting chemotaxis protein YP_001093008.1 hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP YP_001093009.1 protein associated with Co2+ and Mg2+ efflux YP_001093010.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_001093011.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_001093012.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: she:Shewmr4_0907 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001093013.1 PFAM: OstA family protein; Organic solvent tolerance protein; KEGG: shm:Shewmr7_3112 organic solvent tolerance protein YP_001093014.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_3111 aminoglycoside phosphotransferase YP_001093015.1 PFAM: Nucleotidyl transferase; KEGG: shm:Shewmr7_3110 nucleotidyl transferase YP_001093016.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_001093017.1 KEGG: she:Shewmr4_0912 hypothetical protein YP_001093018.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: shm:Shewmr7_3107 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding protein YP_001093019.1 KEGG: shm:Shewmr7_3097 hypothetical protein YP_001093020.1 PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_3016 secretion protein HlyD family protein YP_001093021.1 KEGG: vch:VC1406 methyl-accepting chemotaxis protein; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001093022.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3100 AAA ATPase, central domain protein YP_001093023.1 KEGG: she:Shewmr4_3009 hypothetical protein YP_001093024.1 PFAM: protein of unknown function DUF1289; KEGG: she:Shewmr4_3008 protein of unknown function DUF1289 YP_001093025.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3007 periplasmic sensor signal transduction histidine kinase YP_001093026.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_3087 two component transcriptional regulator, winged helix family YP_001093027.1 KEGG: son:SO3593 hypothetical protein YP_001093028.1 PFAM: MltA-interacting MipA family protein; KEGG: son:SO3592 putative outer membrane protein YP_001093029.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sdn:Sden_3019 regulatory protein, LysR YP_001093030.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sdn:Sden_3018 acyl-CoA dehydrogenase-like protein YP_001093031.1 PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein; KEGG: sdn:Sden_3017 transketolase, central region YP_001093032.1 KEGG: sdn:Sden_3016 (acyl-carrier-protein) S-malonyltransferase YP_001093033.1 PFAM: GCN5-related N-acetyltransferase; KEGG: ppr:PBPRB0529 hypothetical acetyltransferase YP_001093034.1 PFAM: GPR1/FUN34/yaaH family protein; KEGG: ppr:PBPRA2415 putative membrane protein YP_001093035.1 PFAM: response regulator receiver; KEGG: cps:CPS_4695 response regulator YP_001093036.1 PFAM: Hpt domain protein; KEGG: nmu:Nmul_A1556 multi-sensor hybrid histidine kinase YP_001093037.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; KEGG: cyb:CYB_0507 sensory box histidine kinase/response regulator YP_001093038.1 PFAM: OmpA/MotB domain protein; 17 kDa surface antigen; KEGG: sfr:Sfri_1135 OmpA/MotB domain protein YP_001093039.1 KEGG: shm:Shewmr7_3082 hypothetical protein YP_001093040.1 KEGG: sdy:SDY_1697 hypothetical protein YP_001093043.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: shm:Shewmr7_3081 glyoxalase/bleomycin resistance protein/dioxygenase YP_001093044.1 PFAM: NADPH-dependent FMN reductase; KEGG: son:SO3585 azoreductase, putative YP_001093045.1 KEGG: she:Shewmr4_2998 putative transcriptional regulator YP_001093046.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: sdn:Sden_2876 pseudouridine synthase, Rsu YP_001093047.1 PFAM: regulatory protein, LysR; KEGG: son:SO1661 transcriptional regulator, LysR family YP_001093048.1 KEGG: sfr:Sfri_0913 decaheme cytochrome c YP_001093049.1 PFAM: EAL domain protein; phosphotransferase system, EIIC; KEGG: shm:Shewmr7_3254 diguanylate phosphodiesterase YP_001093050.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_2826 major facilitator superfamily MFS_1 YP_001093051.1 KEGG: hch:HCH_03041 hypothetical protein YP_001093052.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: vch:VC1643 methyl-accepting chemotaxis protein YP_001093053.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_001093054.1 PFAM: DNA polymerase III chi subunit, HolC; KEGG: shm:Shewmr7_1202 DNA polymerase III chi subunit, HolC YP_001093055.1 KEGG: msu:MS0989 hypothetical protein YP_001093056.1 KEGG: hso:HS_1731 Haemophilus-specific protein, uncharacterized YP_001093057.1 PFAM: Amidohydrolase 3; KEGG: mmc:Mmcs_3318 twin-arginine translocation pathway signal YP_001093058.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein YP_001093059.1 PFAM: Ig family protein; KEGG: shm:Shewmr7_0560 putative outer membrane adhesin like protein YP_001093060.1 PFAM: AMMECR1 domain protein; KEGG: mag:amb3706 predicted dioxygenase YP_001093061.1 PFAM: protein of unknown function DUF52; KEGG: hch:HCH_05946 predicted dioxygenase YP_001093062.1 PFAM: Radical SAM domain protein; KEGG: hch:HCH_05222 pyruvate-formate lyase-activating enzyme YP_001093063.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: dps:DP0496 hypothetical protein YP_001093064.1 PFAM: TPR repeat-containing protein; SMART: Tetratricopeptide domain protein; KEGG: ppr:PBPRA2309 hypothetical protein YP_001093065.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; SMART: Dystroglycan-type cadherin domain protein; KEGG: shm:Shewmr7_0825 protease-associated PA domain protein YP_001093066.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; KEGG: son:SO3800 serine protease, subtilase family YP_001093067.1 PFAM: transcriptional regulator domain protein; KEGG: she:Shewmr4_2883 transcriptional regulator domain protein YP_001093068.1 KEGG: sde:Sde_1353 TonB-dependent receptor YP_001093069.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_001093070.1 PFAM: permease YjgP/YjgQ family protein; KEGG: she:Shewmr4_2826 permease YjgP/YjgQ family protein YP_001093071.1 PFAM: permease YjgP/YjgQ family protein; KEGG: she:Shewmr4_2825 permease YjgP/YjgQ family protein YP_001093072.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_2823 RDD domain containing protein YP_001093073.1 KEGG: she:Shewmr4_2822 hypothetical protein YP_001093074.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_2903 GCN5-related N-acetyltransferase YP_001093075.1 PFAM: protein of unknown function DUF1449; KEGG: shm:Shewmr7_2900 protein of unknown function DUF1449 YP_001093076.1 PFAM: band 7 protein; KEGG: shm:Shewmr7_2899 band 7 protein YP_001093077.1 PFAM: peptidase M32, carboxypeptidase Taq metallopeptidase; KEGG: shm:Shewmr7_2902 carboxypeptidase Taq YP_001093078.1 KEGG: son:SO1380 hypothetical protein YP_001093079.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sfr:Sfri_3069 redoxin domain protein YP_001093080.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO1383 ATP-dependent RNA helicase, DEAD box family YP_001093081.1 PFAM: EAL domain protein; response regulator receiver; KEGG: pha:PSHAa0134 hypothetical protein YP_001093082.1 PFAM: peptidase M24; KEGG: she:Shewmr4_2807 peptidase M24 YP_001093083.1 PFAM: major facilitator superfamily MFS_1; KEGG: sde:Sde_3481 conserved hypothetical drug transport transmembrane protein YP_001093084.1 PFAM: ROK family protein; KEGG: son:SO1389 ROK family protein YP_001093085.1 PFAM: peptidase M24; KEGG: sfr:Sfri_3046 peptidase M24 YP_001093086.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO1390 peptidyl-prolyl cis-trans isomerase, FKBP-type YP_001093087.1 PFAM: protein of unknown function DUF1294; KEGG: shm:Shewmr7_2883 protein of unknown function DUF1294 YP_001093088.1 KEGG: sfr:Sfri_0740 hypothetical protein YP_001093089.1 KEGG: sdn:Sden_2841 hypothetical protein YP_001093090.1 PFAM: protein of unknown function DUF368; KEGG: sdn:Sden_2840 protein of unknown function DUF368 YP_001093091.1 KEGG: shm:Shewmr7_1246 hypothetical protein YP_001093092.1 KEGG: shm:Shewmr7_1247 hypothetical protein YP_001093093.1 KEGG: she:Shewmr4_2930 hypothetical protein YP_001093094.1 PFAM: protein of unknown function DUF861, cupin_3; KEGG: shm:Shewmr7_3011 protein of unknown function DUF861, cupin_3 YP_001093095.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2928 methylmalonate-semialdehyde dehydrogenase YP_001093096.1 catalyzes the formation of pyruvate and beta-alanine from L-alanine and 3-oxopropanoate YP_001093097.1 PFAM: aldehyde dehydrogenase; KEGG: sfr:Sfri_3021 aldehyde dehydrogenase (NAD(+)) YP_001093098.1 PFAM: Rhodanese domain protein; KEGG: shm:Shewmr7_3006 3-mercaptopyruvate sulfurtransferase YP_001093099.1 PFAM: FAD dependent oxidoreductase; KEGG: she:Shewmr4_2922 FAD dependent oxidoreductase YP_001093100.1 PFAM: helix-turn-helix domain protein; Cupin 2, conserved barrel domain protein; KEGG: shm:Shewmr7_3003 transcriptional regulator, XRE family with cupin sensor YP_001093101.1 PFAM: peptidase C26; KEGG: sfr:Sfri_3012 peptidase C26 YP_001093102.1 PFAM: glutamine synthetase, catalytic region; KEGG: shm:Shewmr7_3001 glutamate--ammonia ligase YP_001093103.1 PFAM: extracellular solute-binding protein, family 1; KEGG: she:Shewmr4_2918 extracellular solute-binding protein, family 1 YP_001093104.1 KEGG: shm:Shewmr7_2999 spermidine/putrescine ABC transporter ATPase subunit; TIGRFAM: spermidine/putrescine ABC transporter ATPase subunit; PFAM: ABC transporter-related protein; Transport-associated OB domain protein; SMART: AAA ATPase YP_001093105.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2998 binding-protein-dependent transport systems inner membrane component YP_001093106.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2997 binding-protein-dependent transport systems inner membrane component YP_001093107.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2996 FAD dependent oxidoreductase YP_001093108.1 PFAM: band 7 protein; KEGG: ecp:ECP_2928 putative SPFH domain protein YP_001093109.1 KEGG: sfr:Sfri_3384 response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001093110.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; KEGG: pat:Patl_2104 multi-sensor hybrid histidine kinase YP_001093111.1 PFAM: response regulator receiver; KEGG: sdn:Sden_1684 GGDEF domain YP_001093112.1 PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: vpa:VP1365 hypothetical protein YP_001093113.1 PFAM: amidohydrolase; KEGG: mba:Mbar_A1663 hypothetical protein YP_001093114.1 PFAM: beta-lactamase; KEGG: cps:CPS_2086 putative beta-lactamase YP_001093115.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: aci:ACIAD1881 putative phospholipase D protein YP_001093116.1 KEGG: vpa:VP2266 hypothetical protein YP_001093118.1 KEGG: rme:Rmet_2827 putative TraY/DotA-like type IV secretion system protein YP_001093119.1 PFAM: MobA/MobL protein; KEGG: atc:AGR_L_66 hypothetical protein YP_001093121.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: psb:Psyr_2668 helix-turn-helix, fis-type YP_001093122.1 PFAM: BsuBIPstI restriction endonuclease domain protein; KEGG: ssn:SSO_1584 putative restriction endonuclease YP_001093123.1 PFAM: Eco57I restriction endonuclease; KEGG: ssn:SSO_1583 putative methylase YP_001093124.1 KEGG: ecs:pO157p27 KfrAs YP_001093125.1 PFAM: phage integrase family protein; KEGG: bxe:Bxe_A3110 putative phage integrase YP_001093126.1 TIGRFAM: RNA polymerase sigma factor RpoD; RNA polymerase sigma factor RpoD domain protein; PFAM: sigma-70 1.1 domain protein; sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70, non-essential domain protein; sigma-70 region 1.2; KEGG: she:Shewmr4_2908 RNA polymerase, sigma 70 subunit, RpoD YP_001093127.1 KEGG: shm:Shewmr7_2989 DNA primase; TIGRFAM: DNA primase; PFAM: zinc finger, CHC2-family protein; TOPRIM domain protein; DNA primase DnaG, DnaB-binding; DNA primase catalytic core, N-terminal domain; SMART: Toprim sub domain protein YP_001093128.1 PFAM: GatB/Yqey domain protein; KEGG: she:Shewmr4_2906 GatB/YqeY domain protein YP_001093129.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_001093130.1 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity YP_001093131.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_001093132.1 TIGRFAM: dihydroneopterin aldolase; KEGG: sdn:Sden_2828 dihydroneopterin aldolase YP_001093133.1 TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; KEGG: she:Shewmr4_2901 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_001093134.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_001093135.1 PFAM: Methyltransferase type 11; KEGG: she:Shewmr4_2899 rRNA (guanine-N(1)-)-methyltransferase YP_001093136.1 PFAM: Peptidoglycan-binding LysM; ErfK/YbiS/YcfS/YnhG family protein; KEGG: vpa:VPA1470 hypothetical protein YP_001093137.1 KEGG: son:SO1295 major outer membrane lipoprotein, putative YP_001093138.1 PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase, HD sub domain; KEGG: shm:Shewmr7_2979 metal dependent phosphohydrolase YP_001093139.1 PFAM: Peptidoglycan-binding domain 1 protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2896 peptidoglycan-binding domain 1 protein YP_001093140.1 KEGG: she:Shewmr4_2895 general secretion pathway protein B YP_001093141.1 PFAM: Citrate transporter; KEGG: shm:Shewmr7_2976 citrate transporter YP_001093142.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_001093143.1 Catalyzes the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate YP_001093144.1 PFAM: helix-turn-helix domain protein; KEGG: cvi:CV0910 hypothetical protein YP_001093145.1 PFAM: Cl- channel, voltage-gated family protein; KEGG: shm:Shewmr7_2973 Cl-channel, voltage-gated family protein YP_001093146.1 KEGG: shm:Shewmr7_2972 hypothetical protein YP_001093147.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_001093148.1 KEGG: she:Shewmr4_2888 hypothetical protein YP_001093149.1 KEGG: shm:Shewmr7_2969 hypothetical protein YP_001093150.1 catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling YP_001093151.1 PFAM: peptidase M23B; Opacity-associated protein A, N-terminal domain protein; KEGG: shm:Shewmr7_2963 peptidase M23B YP_001093152.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_001093153.1 KEGG: shm:Shewmr7_2960 hypothetical protein YP_001093154.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_2959 protein of unknown function UPF0126 YP_001093155.1 KEGG: son:SO1320 hypothetical protein YP_001093156.1 PFAM: cobalamin biosynthesis protein CbiB; KEGG: she:Shewmr4_2875 cobalamin biosynthesis protein CbiB YP_001093157.1 PFAM: purine and other phosphorylases, family 1; KEGG: she:Shewmr4_2874 methylthioadenosine nucleosidase YP_001093158.1 KEGG: mes:Meso_4150 hypothetical protein YP_001093159.1 KEGG: cyb:CYB_0385 hypothetical protein YP_001093161.1 glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate YP_001093162.1 catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate YP_001093163.1 KEGG: son:SO1326 hypothetical protein; TIGRFAM: conserved hypothetical radical SAM protein; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001093164.1 PFAM: Hpt domain protein; KEGG: shm:Shewmr7_2951 Hpt protein YP_001093165.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1328 transcriptional regulator, LysR family YP_001093166.1 KEGG: shm:Shewmr7_2949 putative adenylate/guanylate cyclase YP_001093167.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_001093168.1 hydrolyzes diadenosine polyphosphate YP_001093169.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; GAF domain protein; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: shm:Shewmr7_2946 PTSINtr with GAF domain, PtsP YP_001093170.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2945 protein of unknown function DUF81 YP_001093171.1 ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived YP_001093172.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_001093173.1 KEGG: son:SO1337 hypothetical protein YP_001093174.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_001093175.1 PFAM: protein of unknown function DUF339; KEGG: shm:Shewmr7_2939 protein of unknown function DUF339 YP_001093176.1 KEGG: she:Shewmr4_2856 hypothetical protein YP_001093177.1 catalyzes the formation of oxaloacetate from L-aspartate YP_001093178.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_001093179.1 PFAM: Anti sigma-E protein RseA family protein; Anti sigma-E protein RseA domain protein; KEGG: shm:Shewmr7_2935 anti sigma-E protein, RseA YP_001093180.1 PFAM: MucB/RseB family protein; KEGG: she:Shewmr4_2852 sigma E regulatory protein, MucB/RseB YP_001093181.1 PFAM: Positive regulator of sigma(E), RseC/MucC; KEGG: sdn:Sden_2769 positive regulator of sigma(E), RseC/MucC YP_001093182.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_001093183.1 KEGG: shm:Shewmr7_2931 signal peptidase I; TIGRFAM: signal peptidase I; PFAM: peptidase S24, S26A and S26B YP_001093184.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_001093185.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_001093186.1 TIGRFAM: DNA repair protein RecO; PFAM: Recombination protein O, RecO; KEGG: shm:Shewmr7_2928 DNA repair protein RecO YP_001093187.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_001093188.1 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids YP_001093189.1 PFAM: protein of unknown function DUF962; KEGG: sfr:Sfri_2924 protein of unknown function DUF962 YP_001093190.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; transporter-associated region; KEGG: sfr:Sfri_2923 protein of unknown function DUF21 YP_001093191.1 PFAM: cytochrome c assembly protein; KEGG: shm:Shewmr7_2922 cytochrome c assembly protein YP_001093192.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_001093193.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_001093194.1 Essential for efficient processing of 16S rRNA YP_001093195.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_001093196.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_001093197.1 catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive YP_001093198.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_001093199.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_001093200.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: sfr:Sfri_3608 oxidoreductase FAD-binding domain protein YP_001093201.1 KEGG: son:SO1365 hypothetical protein YP_001093202.1 TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: shm:Shewmr7_2910 chorismate mutase YP_001093203.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_1203 sigma 54 modulation protein/ribosomal protein S30EA YP_001093204.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_1133 cytochrome b561 YP_001093205.1 PFAM: cytochrome c, class II; KEGG: sfr:Sfri_2910 cytochrome c, class II YP_001093206.1 TIGRFAM: trp operon repressor; PFAM: Trp repressor; KEGG: sdn:Sden_2743 Trp repressor YP_001093207.1 KEGG: shm:Shewmr7_1207 hypothetical protein YP_001093208.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: son:SO3417 peptidyl-prolyl cis-trans isomerase SlyD YP_001093209.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_001093210.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_001093211.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_001093212.1 KEGG: shm:Shewmr7_1212 hypothetical protein YP_001093213.1 KEGG: spt:SPA0648 endonuclease IV; TIGRFAM: apurinic endonuclease Apn1; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2 YP_001093214.1 KEGG: mag:amb3313 signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001093215.1 PFAM: response regulator receiver; KEGG: dar:Daro_3172 response regulator receiver YP_001093216.1 PFAM: Hemerythrin HHE cation binding domain protein; KEGG: sdn:Sden_2737 hemerythrin HHE cation binding region YP_001093217.1 KEGG: sfr:Sfri_2902 hypothetical protein YP_001093218.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_001093219.1 KEGG: sdn:Sden_2734 transaldolase; TIGRFAM: transaldolase; PFAM: Transaldolase YP_001093220.1 PFAM: OmpA domain protein transmembrane region-containing protein; OmpA/MotB domain protein; KEGG: sfr:Sfri_2899 OmpA/MotB domain protein YP_001093221.1 PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase; KEGG: shm:Shewmr7_3047 phosphoketolase YP_001093222.1 TIGRFAM: amino acid carrier protein; PFAM: sodium:alanine symporter; KEGG: dps:DP1274 probable sodium/alanine symporter YP_001093223.1 PFAM: protein of unknown function DUF328; KEGG: ppr:PBPRA0561 hypothetical protein YP_001093224.1 PFAM: peptidase M20; peptidase M28; KEGG: she:Shewmr4_2962 peptidase M28 YP_001093225.1 PFAM: regulatory protein, ArsR; KEGG: shm:Shewmr7_3043 transcriptional regulator, ArsR family YP_001093226.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_001093227.1 TIGRFAM: integral membrane protein MviN; PFAM: virulence factor MVIN family protein; KEGG: she:Shewmr4_2959 integral membrane protein MviN YP_001093228.1 TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; KEGG: she:Shewmr4_2958 riboflavin biosynthesis protein RibF YP_001093229.1 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme YP_001093230.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_001093231.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_3037 peptidylprolyl isomerase, FKBP-type YP_001093232.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_001093233.1 TIGRFAM: type IV pilus modification protein PilV; KEGG: shm:Shewmr7_3035 type IV pilus modification protein PilV YP_001093234.1 KEGG: she:Shewmr4_2952 prepilin-type cleavage/methylation-like protein YP_001093235.1 KEGG: she:Shewmr4_2951 type IV pilus assembly protein PilX YP_001093236.1 KEGG: she:Shewmr4_2950 type IV pilin biogenesis protein, putative YP_001093237.1 KEGG: shm:Shewmr7_3031 methylation site containing protein YP_001093238.1 KEGG: she:Shewmr4_2947 methylation site containing protein YP_001093239.1 KEGG: son:SO3520 type IV pilus biogenesis protein, putative YP_001093240.1 PFAM: nitrogen regulatory protein P-II; KEGG: sdn:Sden_2711 nitrogen regulatory protein P-II YP_001093241.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: son:SO3516 transcriptional regulator, LacI family YP_001093242.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3024 TonB-dependent receptor YP_001093243.1 PFAM: tryptophan halogenase; KEGG: shm:Shewmr7_3023 tryptophan halogenase YP_001093244.1 PFAM: SapC family protein; KEGG: pha:PSHAa1142 hypothetical protein YP_001093245.1 PFAM: glycoside hydrolase, family 20; Carbohydrate-binding, chitobiase/hexosaminidase-type domain protein; glycoside hydrolase, family 20 domain protein; KEGG: she:Shewmr4_2936 beta-N-acetylhexosaminidase YP_001093246.1 PFAM: ATPase, BadF/BadG/BcrA/BcrD type; KEGG: she:Shewmr4_2935 ATPase, BadF/BadG/BcrA/BcrD type YP_001093247.1 KEGG: sdn:Sden_2704 N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; PFAM: amidohydrolase YP_001093248.1 KEGG: shm:Shewmr7_3014 hypothetical protein YP_001093249.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_3013 glucose/galactose transporter YP_001093250.1 PFAM: cytochrome B561; KEGG: son:SO3371 hypothetical cytochrome B561 YP_001093251.1 PFAM: YceI family protein; KEGG: sfr:Sfri_2875 YceI family protein YP_001093252.1 PFAM: Fe(II) trafficking protein YggX; KEGG: sfr:Sfri_2874 Fe(II) trafficking protein YggX YP_001093253.1 TIGRFAM: A/G-specific adenine glycosylase; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; KEGG: she:Shewmr4_1180 A/G-specific adenine glycosylase YP_001093254.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_001093255.1 PFAM: protein of unknown function DUF469; KEGG: sdn:Sden_2696 protein of unknown function DUF469 YP_001093256.1 catalyzes the formation of glutamate from glutamine YP_001093257.1 KEGG: shm:Shewmr7_1255 hypothetical protein YP_001093258.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1256 transcriptional regulator, LysR family YP_001093259.1 KEGG: vfi:VF1468 hypothetical protein YP_001093260.1 PFAM: protein of unknown function DUF885; KEGG: shm:Shewmr7_1257 protein of unknown function DUF885 YP_001093261.1 KEGG: shm:Shewmr7_1258 putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM domain protein; HemN domain protein; SMART: Elongator protein 3/MiaB/NifB YP_001093262.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_001093263.1 KEGG: shm:Shewmr7_1260 hypothetical protein YP_001093264.1 PFAM: protein of unknown function DUF167; KEGG: ppr:PBPRA3146 hypothetical protein YP_001093265.1 PFAM: protein of unknown function YGGT; KEGG: sdn:Sden_2684 protein of unknown function YGGT YP_001093266.1 KEGG: son:SO3354 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein YP_001093267.1 PFAM: alanine racemase domain protein; KEGG: sfr:Sfri_2860 protein of unknown function UPF0001 YP_001093268.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: sfr:Sfri_2859 twitching motility protein YP_001093269.1 TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; KEGG: shm:Shewmr7_1266 twitching motility protein YP_001093270.1 PFAM: ferrochelatase; KEGG: sfr:Sfri_2852 ferrochelatase YP_001093271.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein YP_001093272.1 PFAM: AAA-4 family protein; KEGG: tbd:Tbd_1077 predicted transcriptional regulator YP_001093273.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_001093274.1 PFAM: protein of unknown function DUF179; KEGG: shm:Shewmr7_1270 protein of unknown function DUF179 YP_001093275.1 involved in start site selection during the initiation of translation YP_001093276.1 KEGG: she:Shewmr4_1201 hypothetical protein YP_001093277.1 KEGG: son:SO3343 hypothetical protein YP_001093278.1 KEGG: hch:HCH_04766 hypothetical protein YP_001093279.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_0421 transcription regulator, LysR family YP_001093280.1 PFAM: transmembrane pair domain protein; KEGG: vpa:VP1155 hypothetical protein YP_001093281.1 PFAM: OmpA/MotB domain protein; KEGG: son:SO3339 OmpA family protein YP_001093282.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_1276 MscS mechanosensitive ion channel YP_001093283.1 PFAM: protein of unknown function UPF0126; KEGG: shm:Shewmr7_1274 protein of unknown function UPF0126 YP_001093284.1 PFAM: aminotransferase, class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO3338 L-allo-threonine aldolase YP_001093285.1 KEGG: shm:Shewmr7_0585 hypothetical protein YP_001093286.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0584 alkaline phosphatase YP_001093287.1 PFAM: Alkaline phosphatase; KEGG: shm:Shewmr7_0583 alkaline phosphatase YP_001093288.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2843 thioesterase superfamily protein YP_001093289.1 KEGG: son:SO1487 hypothetical protein YP_001093290.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: stt:t1709 NADH dehydrogenase YP_001093291.1 KEGG: she:Shewmr4_2763 hypothetical protein YP_001093292.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: cps:CPS_1536 efflux transporter, MFP subunit, AcrA/E family YP_001093293.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: vpa:VPA0471 putative multidrug efflux membrane fusion protein YP_001093294.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: ppr:PBPRB1929 putative Cold shock-like protein YP_001093295.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: shm:Shewmr7_2840 iron-containing alcohol dehydrogenase YP_001093296.1 KEGG: son:SO1493 4-alpha-glucanotransferase; TIGRFAM: 4-alpha-glucanotransferase; PFAM: glycoside hydrolase, family 77 YP_001093297.1 catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain YP_001093298.1 KEGG: shm:Shewmr7_2835 glycogen debranching enzyme GlgX; TIGRFAM: glycogen debranching enzyme GlgX; PFAM: glycoside hydrolase, family 13 domain protein; alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain YP_001093299.1 KEGG: she:Shewmr4_2756 glycogen/starch/alpha-glucan phosphorylases; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases; PFAM: glycosyl transferase, family 35 YP_001093300.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_001093301.1 PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: son:SO1499 glycogen synthase YP_001093302.1 PFAM: protein of unknown function DUF88; KEGG: she:Shewmr4_1080 protein of unknown function DUF88 YP_001093303.1 PFAM: sulfotransferase; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: sfr:Sfri_0890 sulfotransferase YP_001093304.1 PFAM: SEC-C motif domain protein; Aspartyl/Asparaginyl beta-hydroxylase; Cupin 2, conserved barrel domain protein; KEGG: sfr:Sfri_0891 sec-C motif domain protein YP_001093305.1 PFAM: sulfotransferase; SEC-C motif domain protein; KEGG: sfr:Sfri_0892 sec-C motif domain protein YP_001093306.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_1150 efflux transporter, RND family, MFP subunit YP_001093307.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1149 acriflavin resistance protein YP_001093308.1 KEGG: she:Shewmr4_1087 type IV pilin biogenesis protein, putative YP_001093309.1 KEGG: she:Shewmr4_1088 hypothetical protein YP_001093310.1 PFAM: PepSY-associated TM helix domain protein; KEGG: cps:CPS_2723 putative iron-regulated membrane protein YP_001093311.1 PFAM: metallophosphoesterase; KEGG: she:Shewmr4_1086 metallophosphoesterase YP_001093312.1 ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence YP_001093313.1 KEGG: ade:Adeh_0489 hypothetical protein YP_001093314.1 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate YP_001093315.1 PFAM: ATP-cone domain protein; KEGG: sfr:Sfri_1034 ribonucleotide reductase regulator NrdR-like protein YP_001093316.1 KEGG: she:Shewmr4_1096 riboflavin biosynthesis protein RibD; TIGRFAM: riboflavin biosynthesis protein RibD; PFAM: CMP/dCMP deaminase, zinc-binding; bifunctional deaminase-reductase domain protein YP_001093317.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001093318.1 PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; KEGG: sdn:Sden_1146 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_001093319.1 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not YP_001093320.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_001093321.1 KEGG: she:Shewmr4_1101 thiamine-monophosphate kinase; TIGRFAM: thiamine-monophosphate kinase; PFAM: AIR synthase related protein domain protein YP_001093322.1 PFAM: phosphatidylglycerophosphatase A; KEGG: son:SO3463 phosphatidylglycerophosphatase A YP_001093323.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: sde:Sde_3850 hypothetical protein YP_001093324.1 KEGG: son:SO2460 hypothetical protein YP_001093325.1 TIGRFAM: DNA repair protein RecN; PFAM: SMC domain protein; KEGG: son:SO3462 DNA repair protein RecN YP_001093326.1 PFAM: Auxin Efflux Carrier; KEGG: shm:Shewmr7_1171 auxin efflux carrier YP_001093327.1 KEGG: sfr:Sfri_1045 hypothetical protein YP_001093328.1 PFAM: protein of unknown function DUF416; KEGG: son:SO3458 hypothetical protein YP_001093329.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_001093330.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_001093331.1 KEGG: shm:Shewmr7_1177 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; RelA/SpoT domain protein YP_001093332.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_001093333.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_001093334.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_001093335.1 PFAM: Septum formation initiator; KEGG: shm:Shewmr7_1187 septum formation initiator YP_001093336.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_001093337.1 catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate YP_001093338.1 PFAM: tRNA pseudouridine synthase D, TruD; KEGG: sfr:Sfri_1056 pseudouridylate synthase YP_001093339.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_001093340.1 KEGG: son:SO3434 protein-L-isoaspartate O-methyltransferase; TIGRFAM: protein-L-isoaspartate O-methyltransferase; PFAM: protein-L-isoaspartate(D-aspartate) O-methyltransferase YP_001093341.1 PFAM: Peptidoglycan-binding LysM; peptidase M23B; KEGG: shm:Shewmr7_1193 peptidase M23B YP_001093342.1 TIGRFAM: RNA polymerase sigma factor RpoS; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; sigma-70 region 1.2; KEGG: sdn:Sden_1204 RNA polymerase sigma factor RpoS YP_001093343.1 This protein performs the mismatch recognition step during the DNA repair process YP_001093344.1 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs YP_001093345.1 PFAM: regulatory protein RecX; KEGG: shm:Shewmr7_1197 regulatory protein RecX YP_001093346.1 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001093347.1 affects carbohydrate metabolism; has regulatory role in many processes YP_001093348.1 TIGRFAM: sodium pump decarboxylases, gamma subunit; PFAM: sodium pump decarboxylase, gamma subunit; KEGG: sfr:Sfri_1065 sodium pump decarboxylases, gamma subunit YP_001093349.1 catalyzes the formation of pyruvate from oxaloacetate YP_001093350.1 KEGG: sfr:Sfri_1067 sodium ion-translocating decarboxylase, beta subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit YP_001093351.1 KEGG: vfi:VF1529 hypothetical protein YP_001093352.1 KEGG: shm:Shewmr7_3066 hypothetical protein YP_001093353.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_3065 sodium:dicarboxylate symporter YP_001093354.1 KEGG: son:SO3561 hypothetical protein YP_001093355.1 PFAM: peptidase M16 domain protein; KEGG: she:Shewmr4_2981 peptidase M16 domain protein YP_001093356.1 involved in the first step of glutathione biosynthesis YP_001093357.1 KEGG: shm:Shewmr7_3061 hypothetical protein YP_001093358.1 KEGG: shm:Shewmr7_3060 hypothetical protein YP_001093359.1 KEGG: ppr:PBPRA3574 hypothetical phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001093360.1 PFAM: sigma-70 region 2 domain protein; KEGG: she:Shewmr4_2972 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001093361.1 KEGG: sfr:Sfri_1079 hypothetical protein YP_001093362.1 KEGG: pat:Patl_1076 hypothetical protein YP_001093363.1 PFAM: peptidase S41; WD40 domain protein beta Propeller; SMART: PDZ/DHR/GLGF domain protein; KEGG: shm:Shewmr7_1214 peptidase S41 YP_001093364.1 KEGG: shm:Shewmr7_2273 hypothetical protein YP_001093365.1 PFAM: OsmC family protein; KEGG: sdn:Sden_1225 OsmC-like protein YP_001093367.1 KEGG: shm:Shewmr7_1217 hypothetical protein YP_001093368.1 PFAM: PepSY-associated TM helix domain protein; KEGG: shm:Shewmr7_1218 PepSY-associated TM helix domain protein YP_001093369.1 KEGG: neu:NE1084 hypothetical protein YP_001093370.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: son:SO3403 ribosomal subunit interface protein YP_001093371.1 KEGG: sdn:Sden_2617 hypothetical protein YP_001093372.1 KEGG: sdn:Sden_2616 peptidyl-Lys metalloendopeptidase YP_001093373.1 PFAM: OsmC family protein; KEGG: vfi:VFA0335 osmotically inducible protein C YP_001093374.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cyb:CYB_1948 transcriptional regulator, LysR family YP_001093376.1 PFAM: protein of unknown function DUF897; KEGG: ttj:TTHA0515 hypothetical protein YP_001093377.1 KEGG: mmr:Mmar10_2567 phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase YP_001093378.1 KEGG: hch:HCH_04604 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); TIGRFAM: phosphoribosylaminoimidazole carboxylase, ATPase subunit; PFAM: ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp YP_001093381.1 KEGG: vfi:VFA0515 transposase YP_001093382.1 KEGG: son:SO1447 retinol acyltransferase domain protein YP_001093383.1 PFAM: phage integrase family protein; KEGG: she:Shewmr4_1694 phage integrase family protein YP_001093384.1 KEGG: shm:Shewmr7_1772 hypothetical protein YP_001093385.1 KEGG: she:Shewmr4_1698 hypothetical protein YP_001093386.1 PFAM: DNA repair protein RadC; KEGG: son:SO1455 DNA repair protein, RadC family YP_001093387.1 PFAM: Prophage CP4-57 regulatory; KEGG: ilo:IL0640 predicted transcriptional regulator YP_001093388.1 PFAM: Prophage CP4-57 regulatory; KEGG: vvy:VV0810 predicted transcriptional regulator YP_001093389.1 PFAM: DNA methylase N-4/N-6 domain protein; KEGG: cgb:cg1028 putative restriction-modification system: methylase YP_001093390.1 PFAM: type III restriction enzyme, res subunit; KEGG: ecj:JW0270 hypothetical protein YP_001093392.1 KEGG: sty:HCM1.102 hypothetical protein YP_001093393.1 PFAM: UvrD/REP helicase; KEGG: sty:HCM1.103 putative DNA helicase YP_001093395.1 PFAM: helix-turn-helix domain protein YP_001093396.1 PFAM: phage integrase family protein; KEGG: she:Shewmr4_2777 phage integrase family protein YP_001093397.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_001093398.1 PFAM: cyclase/dehydrase; KEGG: shm:Shewmr7_2853 cyclase/dehydrase YP_001093399.1 PFAM: protein of unknown function UPF0125; KEGG: sfr:Sfri_1096 protein of unknown function UPF0125 YP_001093400.1 PFAM: SmpA/OmlA domain protein; KEGG: shm:Shewmr7_2851 SmpA/OmlA domain protein YP_001093401.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: she:Shewmr4_2772 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001093402.1 KEGG: sfr:Sfri_1099 hypothetical protein YP_001093403.1 KEGG: son:SO1480 GGDEF family protein; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_001093404.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001093405.1 TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: she:Shewmr4_2766 isocitrate lyase YP_001093406.1 PFAM: GAF domain protein; HDOD; KEGG: sdn:Sden_1247 hypothetical protein YP_001093407.1 KEGG: shm:Shewmr7_1280 hypothetical protein YP_001093408.1 PFAM: protein of unknown function DUF980; KEGG: sfr:Sfri_1105 protein of unknown function DUF980 YP_001093409.1 KEGG: she:Shewmr4_1213 transcriptional regulator, CopG family YP_001093410.1 KEGG: shm:Shewmr7_1285 hypothetical protein YP_001093411.1 KEGG: shm:Shewmr7_1287 hypothetical protein YP_001093412.1 KEGG: son:SO3325 NrfJ-related protein YP_001093413.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1289 GCN5-related N-acetyltransferase YP_001093414.1 PFAM: metallophosphoesterase; 5'-Nucleotidase domain protein; KEGG: she:Shewmr4_1223 metallophosphoesterase YP_001093415.1 PFAM: CBS domain containing protein; protein of unknown function DUF21; KEGG: shm:Shewmr7_1295 protein of unknown function DUF21 YP_001093416.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_001093417.1 KEGG: shm:Shewmr7_1297 type IV pilus biogenesis/stability protein PilW; TIGRFAM: type IV pilus biogenesis/stability protein PilW; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein YP_001093418.1 KEGG: sfr:Sfri_1115 hypothetical protein YP_001093419.1 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis YP_001093420.1 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG YP_001093421.1 PFAM: Tetratricopeptide TPR_4; KEGG: shm:Shewmr7_1301 hypothetical protein YP_001093422.1 with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis YP_001093423.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_001093424.1 KEGG: vpa:VP2004 hypothetical protein YP_001093425.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_001093426.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_001093427.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_001093428.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: she:Shewmr4_1236 CMP/dCMP deaminase, zinc-binding YP_001093429.1 YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function YP_001093430.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_001093431.1 PFAM: cytochrome bd ubiquinol oxidase, subunit I; KEGG: shm:Shewmr7_1310 cytochrome bd ubiquinol oxidase, subunit I YP_001093432.1 TIGRFAM: cytochrome d ubiquinol oxidase, subunit II; PFAM: cytochrome bd ubiquinol oxidase, subunit II; KEGG: son:SO3285 cytochrome bd-I oxidase subunit II YP_001093433.1 TIGRFAM: cyd operon protein YbgT; PFAM: membrane bound YbgT family protein; KEGG: sfr:Sfri_1144 cyd operon protein YbgT YP_001093434.1 PFAM: HNH endonuclease; SMART: HNH nuclease YP_001093435.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: tma:TM1828 diaminohydroxyphosphoribosylaminopyrimidine deaminase / 5-amino-6-(5-phosphoribosylamino)uracil reductase YP_001093438.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_1243 methyl-accepting chemotaxis sensory transducer YP_001093439.1 PFAM: acriflavin resistance protein; KEGG: sdn:Sden_1277 acriflavin resistance protein YP_001093440.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: son:SO3278 hypothetical protein YP_001093441.1 PFAM: regulatory protein, TetR; KEGG: sdn:Sden_1279 regulatory protein, TetR YP_001093442.1 KEGG: sfr:Sfri_1150 hypothetical protein YP_001093443.1 KEGG: shm:Shewmr7_1319 hypothetical protein YP_001093444.1 KEGG: sdn:Sden_1282 hypothetical protein YP_001093445.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: sdn:Sden_1285 protein of unknown function DUF115 YP_001093446.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; Male sterility C-terminal domain; KEGG: son:SO3271 polysaccharide biosynthesis protein YP_001093447.1 PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG: sdn:Sden_1287 DegT/DnrJ/EryC1/StrS aminotransferase YP_001093448.1 PFAM: Methyltransferase type 12; KEGG: sdn:Sden_3104 methyltransferase type 12 YP_001093449.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_3105 methyltransferase type 12 YP_001093450.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3106 short-chain dehydrogenase/reductase SDR YP_001093451.1 KEGG: sdn:Sden_3107 acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II-like protein YP_001093452.1 KEGG: sdn:Sden_3108 hypothetical protein YP_001093453.1 KEGG: sdn:Sden_3109 acetyltransferases including N-acetylases of ribosomal proteins-like protein YP_001093454.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3110 short-chain dehydrogenase/reductase SDR YP_001093455.1 KEGG: sdn:Sden_3111 hypothetical protein YP_001093456.1 PFAM: acylneuraminate cytidylyltransferase; KEGG: sdn:Sden_3112 acylneuraminate cytidylyltransferase YP_001093457.1 PFAM: N-acetylneuraminic acid synthase, N-terminal domain; SAF domain; KEGG: sdn:Sden_3113 N-acetylneuraminic acid synthase-like protein YP_001093458.1 PFAM: Rieske [2Fe-2S] domain protein; KEGG: sdn:Sden_3114 Rieske (2Fe-2S) region YP_001093459.1 KEGG: sdn:Sden_3115 spore coat polysaccharide biosynthesis protein predicted glycosyltransferase-like protein YP_001093460.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: sdn:Sden_3118 short-chain dehydrogenase/reductase SDR YP_001093461.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: sdn:Sden_3119 3-oxoacyl-(acyl-carrier protein) synthase YP_001093462.1 PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: sdn:Sden_3120 3-oxoacyl-(acyl-carrier protein) synthase YP_001093463.1 KEGG: son:SO3260 hypothetical protein YP_001093464.1 KEGG: son:SO3259 hypothetical protein YP_001093465.1 KEGG: shm:Shewmr7_1321 hypothetical protein YP_001093466.1 KEGG: shm:Shewmr7_1322 hypothetical protein YP_001093467.1 PFAM: protein of unknown function DUF400; KEGG: shm:Shewmr7_1323 protein of unknown function DUF400 YP_001093468.1 PFAM: FlgN family protein; KEGG: shm:Shewmr7_1324 FlgN family protein YP_001093469.1 PFAM: Anti-sigma-28 factor, FlgM family protein; KEGG: sfr:Sfri_1157 anti-sigma-28 factor, FlgM YP_001093470.1 required for the assembly of the flagellar basal body P-ring YP_001093471.1 PFAM: response regulator receiver; CheW domain protein; KEGG: she:Shewmr4_1257 response regulator receiver modulated CheW protein YP_001093472.1 PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 12; KEGG: shm:Shewmr7_1328 MCP methyltransferase, CheR-type YP_001093473.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod YP_001093474.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_001093475.1 acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production YP_001093476.1 the hook connects flagellar basal body to the flagellar filament YP_001093477.1 FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod YP_001093478.1 makes up the distal portion of the flagellar basal body rod YP_001093479.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001093480.1 part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum YP_001093481.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_001093482.1 TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: shm:Shewmr7_1338 flagellar hook-associated protein FlgK YP_001093483.1 with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes. YP_001093484.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1314 flagellin-like protein YP_001093485.1 PFAM: flagellin domain protein; KEGG: sdn:Sden_1315 flagellin-like protein YP_001093486.1 PFAM: flagellar protein FlaG protein; KEGG: son:SO3236 flagellin FlaG YP_001093487.1 PFAM: flagellar hook-associated protein 2 domain protein; flagellar hook-associated 2 domain protein; flagellin hook IN repeat protein; KEGG: son:SO3235 flagellar hook-associated protein FliD YP_001093488.1 KEGG: sdn:Sden_1318 hypothetical protein YP_001093489.1 flagellin specific chaperone YP_001093490.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; flagellar regulatory FleQ domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_1278 sigma54 specific transcriptional regulator, fis family YP_001093491.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: PAS domain containing protein; KEGG: she:Shewmr4_1279 PAS/PAC sensor signal transduction histidine kinase YP_001093492.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_1180 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001093493.1 TIGRFAM: flagellar hook-basal body complex subunit FliE; PFAM: flagellar hook-basal body complex protein FliE; KEGG: shm:Shewmr7_1348 flagellar hook-basal body complex subunit FliE YP_001093494.1 the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod YP_001093495.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001093496.1 PFAM: flagellar assembly protein FliH; KEGG: shm:Shewmr7_1351 flagellar assembly protein FliH YP_001093497.1 involved in type III protein export during flagellum assembly YP_001093498.1 TIGRFAM: flagellar export protein FliJ; KEGG: shm:Shewmr7_1353 flagellar export protein FliJ YP_001093499.1 PFAM: flagellar hook-length control protein; KEGG: sfr:Sfri_1187 flagellar hook-length control protein YP_001093500.1 interacts with the cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_001093501.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_001093502.1 One of three proteins involved in switching the direction of the flagellar rotation YP_001093503.1 PFAM: flagellar biosynthesis protein, FliO; KEGG: sfr:Sfri_1191 flagellar biosynthesis protein, FliO YP_001093504.1 FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus YP_001093505.1 TIGRFAM: flagellar biosynthetic protein FliQ; PFAM: export protein FliQ, family 3; KEGG: sdn:Sden_1337 flagellar biosynthetic protein FliQ YP_001093506.1 FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus YP_001093507.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_001093508.1 membrane protein involved in the flagellar export apparatus YP_001093509.1 positive regulator of class III flagellar genes YP_001093510.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1365 cobyrinic acid a,c-diamide synthase YP_001093511.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_001093512.1 PFAM: response regulator receiver; KEGG: shm:Shewmr7_1367 response regulator receiver protein YP_001093513.1 PFAM: Chemotaxis phosphatase, CheZ; KEGG: sfr:Sfri_1201 chemotaxis phosphatase, CheZ YP_001093514.1 PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: shm:Shewmr7_1369 CheA signal transduction histidine kinases YP_001093515.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_001093516.1 KEGG: shm:Shewmr7_1371 hypothetical protein YP_001093517.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_1372 cobyrinic acid a,c-diamide synthase YP_001093518.1 PFAM: CheW domain protein; KEGG: shm:Shewmr7_1373 CheW protein YP_001093519.1 PFAM: CheW domain protein; KEGG: shm:Shewmr7_1374 CheW protein YP_001093520.1 KEGG: shm:Shewmr7_1375 hypothetical protein YP_001093521.1 KEGG: shm:Shewmr7_1376 FlhB domain protein YP_001093522.1 KEGG: she:Shewmr4_1310 hypothetical protein YP_001093523.1 PFAM: VacJ family lipoprotein; KEGG: shm:Shewmr7_1378 VacJ family lipoprotein YP_001093524.1 PFAM: response regulator receiver; KEGG: son:SO3196 response regulator YP_001093525.1 TIGRFAM: amino acid/peptide transporter; PFAM: TGF-beta receptor, type I/II extracellular region; major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1380 amino acid/peptide transporter YP_001093526.1 KEGG: sfr:Sfri_2844 NusG antitermination factor; TIGRFAM: transcriptional activator RfaH; PFAM: transcription antitermination protein NusG; SMART: NGN domain protein YP_001093527.1 PFAM: polysaccharide export protein; KEGG: son:SO3193 polysaccharide biosynthesis protein YP_001093528.1 PFAM: lipopolysaccharide biosynthesis protein; KEGG: son:SO3191 chain length determinant protein YP_001093529.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_001093530.1 TIGRFAM: glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfr:Sfri_2829 glucose-1-phosphate thymidylyltransferase YP_001093531.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sdn:Sden_2661 dTDP-4-dehydrorhamnose reductase YP_001093532.1 KEGG: sfr:Sfri_2827 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001093533.1 PFAM: glycosyl transferase, group 1; KEGG: sfr:Sfri_2826 glycosyl transferase, group 1 YP_001093534.1 PFAM: polysaccharide biosynthesis protein; KEGG: bfs:BF2791 putative transmembrane protein YP_001093535.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: blo:BL0232 probable 3-oxoacyl-[acyl-carrier protein] reductase YP_001093536.1 PFAM: thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: blo:BL0231 2-oxoglutarate decarboxylase / 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase YP_001093537.1 KEGG: bfs:BF2794 hypothetical protein YP_001093538.1 PFAM: glycosyl transferase, group 1; KEGG: sat:SYN_00823 glycosyltransferase YP_001093539.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: pfl:PFL_5101 O-acetyltransferase, putative YP_001093540.1 KEGG: ter:Tery_3239 tetratricopeptide TPR_2 YP_001093542.1 PFAM: glycosyl transferase, family 2; KEGG: bfs:BF1562 putative glycosyltransferase O-antigen related protein YP_001093543.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4; KEGG: sfr:Sfri_2825 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001093544.1 TIGRFAM: undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase; PFAM: glycosyl transferase, family 4; KEGG: shm:Shewmr7_1397 undecaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphatetransferase YP_001093545.1 TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; KEGG: sfr:Sfri_2823 UTP-glucose-1-phosphate uridylyltransferase YP_001093546.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sfr:Sfri_3709 PHP C-terminal domain protein YP_001093548.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_001093549.1 KEGG: cps:CPS_2143 sulfate adenylate transferase, subunit 1; TIGRFAM: small GTP-binding protein; sulfate adenylyltransferase, large subunit; PFAM: protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein YP_001093550.1 PFAM: Citrate transporter; TrkA-C domain protein; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: cps:CPS_2144 putative transporter YP_001093551.1 PFAM: adenylylsulfate kinase; KEGG: cps:CPS_2145 adenylylsulfate kinase YP_001093552.1 KEGG: sfr:Sfri_3925 hypothetical protein YP_001093553.1 TIGRFAM: 3'(2'),5'-bisphosphate nucleotidase; PFAM: inositol monophosphatase; KEGG: sfr:Sfri_1320 3'(2'),5'-bisphosphate nucleotidase YP_001093554.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_001093555.1 PFAM: protein of unknown function DUF218; KEGG: son:SO1657 hypothetical protein YP_001093556.1 KEGG: sdn:Sden_2599 hypothetical protein YP_001093557.1 PFAM: protein of unknown function DUF583; KEGG: sfr:Sfri_3256 protein of unknown function DUF583 YP_001093558.1 TIGRFAM: ferredoxin-type protein NapF; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfr:Sfri_1326 ferredoxin-type protein NapF YP_001093559.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_2676 UDP-glucose 4-epimerase YP_001093560.1 KEGG: son:SO1665 UTP--glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase YP_001093561.1 phenylalanine 4-hydroxylase; phenylalanine 4-hydroxylase; catalyzes the formation of 4a-hydroxytetrahydrobiopterin and tyrosine from phenylalanine and tetrahydrobiopterin YP_001093562.1 4-alpha-hydroxytetrahydrobiopterin dehydratase activity; catalyzes the formation of (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7, 8-dihydro-6H-pterin from (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7, 8-tetrahydro-4a-hydroxypterin; functions in recycling tetrahydrobiopterin (BH4) in phenylalanine hydroxylase reaction YP_001093563.1 PFAM: sigma-54 factor, interaction domain-containing protein; amino acid-binding ACT domain protein; SMART: AAA ATPase; KEGG: son:SO1669 transcriptional regulatory protein TyrR YP_001093564.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: sdn:Sden_2592 fumarylacetoacetate (FAA) hydrolase YP_001093565.1 TIGRFAM: maleylacetoacetate isomerase; PFAM: Glutathione S-transferase, N-terminal domain; KEGG: shm:Shewmr7_2670 maleylacetoacetate isomerase YP_001093566.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_1696 transcriptional regulator, LysR family YP_001093567.1 PFAM: major facilitator superfamily MFS_1; KEGG: son:SO1917 multidrug resistance protein, putative YP_001093568.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: son:SO3138 C4-dicarboxylate transport transcriptional regulatory protein YP_001093569.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_1360 periplasmic sensor signal transduction histidine kinase YP_001093570.1 TIGRFAM: TRAP dicarboxylate transporter, DctM subunit; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: sfr:Sfri_2717 TRAP dicarboxylate transporter, DctM subunit YP_001093571.1 PFAM: Tripartite ATP-independent periplasmic transporter, DctQ component; KEGG: shm:Shewmr7_1427 tripartite ATP-independent periplasmic transporter, DctQ component YP_001093572.1 TIGRFAM: TRAP dicarboxylate transporter, DctP subunit; PFAM: TRAP dicarboxylate transporter- DctP subunit; KEGG: sfr:Sfri_2715 TRAP dicarboxylate transporter, DctP subunit YP_001093573.1 PFAM: major facilitator superfamily MFS_1; KEGG: ftf:FTF0444 multidrug transporter (tetracycline resistance protein) YP_001093574.1 KEGG: shm:Shewmr7_1429 hypothetical protein YP_001093575.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_001093576.1 KEGG: cps:CPS_2544 putative cytochrome P460 YP_001093577.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_1431 ABC transporter-related protein YP_001093578.1 PFAM: helix-turn-helix- domain containing protein, AraC type; Ada, metal-binding domain protein; AlkA domain protein; SMART: HhH-GPD family protein; KEGG: she:Shewmr4_1367 transcriptional regulator, AraC family YP_001093579.1 KEGG: shm:Shewmr7_1433 methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: methylated-DNA--protein-cysteine methyltransferase; PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; methylguanine DNA methyltransferase, ribonuclease domain protein YP_001093580.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO3125 ATP-dependent RNA helicase, DEAD box family YP_001093581.1 PFAM: Dual specificity protein phosphatase; KEGG: son:SO3124 tyrosine-specific protein phosphatase, putative YP_001093582.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: shm:Shewmr7_1436 phospholipase D/transphosphatidylase YP_001093583.1 PFAM: response regulator receiver; CheW domain protein; KEGG: shm:Shewmr7_1437 response regulator receiver modulated CheW protein YP_001093584.1 involved in the import of serine and threonine coupled with the import of sodium YP_001093585.1 KEGG: son:SO3119 hypothetical protein YP_001093586.1 PFAM: pseudouridine synthase; KEGG: sdn:Sden_2524 pseudouridylate synthase YP_001093587.1 KEGG: cps:CPS_1467 zinc carboxypeptidase-related protein YP_001093588.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: son:SO0765 threonine efflux protein, putative YP_001093589.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO0766 transcriptional regulator, AraC/XylS family YP_001093590.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_001093591.1 KEGG: she:Shewmr4_2245 hypothetical protein YP_001093592.1 KEGG: she:Shewmr4_2244 hypothetical protein YP_001093593.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: sdn:Sden_1435 GGDEF domain YP_001093595.1 KEGG: gsu:GSU0552 hypothetical protein YP_001093596.1 PFAM: sulfatase; KEGG: shm:Shewmr7_2295 sulfatase YP_001093597.2 PFAM: protein of unknown function DUF1414; KEGG: shm:Shewmr7_2294 protein of unknown function DUF1414 YP_001093598.1 PFAM: 37 kDa nucleoid-associated protein; KEGG: she:Shewmr4_2217 37 kDa nucleoid-associated protein YP_001093599.1 KEGG: sdn:Sden_2379 hypothetical protein YP_001093600.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_2290 peptidase M23B YP_001093601.1 KEGG: sdn:Sden_3375 hypothetical protein YP_001093602.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001093603.1 TIGRFAM: anti-sigma factor, putative, ChrR family; KEGG: sdn:Sden_3373 anti-sigma factor ChrR , putative YP_001093604.1 PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: cps:CPS_1379 hypothetical protein YP_001093605.1 PFAM: DNA photolyase, FAD-binding; DNA photolyase domain protein; KEGG: pha:PSHAb0453 putative deoxyribodipyrimidine photolyase YP_001093606.1 PFAM: protein of unknown function DUF1486; KEGG: sdn:Sden_3372 hypothetical protein YP_001093607.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_3371 short-chain dehydrogenase/reductase SDR YP_001093608.1 PFAM: amine oxidase; KEGG: sdn:Sden_3370 amine oxidase YP_001093609.1 PFAM: protein of unknown function DUF1365; KEGG: sdn:Sden_3369 protein of unknown function DUF1365 YP_001093610.1 PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_3368 cyclopropane-fatty-acyl-phospholipid synthase YP_001093611.1 KEGG: sdn:Sden_3367 hypothetical protein YP_001093612.1 KEGG: sdn:Sden_3366 hypothetical protein YP_001093613.1 KEGG: sdn:Sden_3365 hypothetical protein YP_001093614.1 PFAM: FAD linked oxidase domain protein; Berberine/berberine domain protein; KEGG: vpa:VPA0635 putative oxidoreductase, oxygen dependent, FAD-dependent protein YP_001093615.1 PFAM: protein of unknown function DUF991; KEGG: sdn:Sden_2377 protein of unknown function DUF991 YP_001093616.1 PFAM: ErfK/YbiS/YcfS/YnhG family protein; KEGG: shm:Shewmr7_2287 hypothetical protein YP_001093617.1 PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: she:Shewmr4_2209 ion transport protein YP_001093618.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; virulence factor MVIN family protein; KEGG: son:SO1918 MATE efflux family protein YP_001093619.1 KEGG: son:SO1921 hypothetical protein YP_001093620.1 PFAM: uncharacterized conserved protein UCP029143; KEGG: vvu:VV20047 hypothetical protein YP_001093621.1 KEGG: abo:ABO_1607 hypothetical protein YP_001093622.1 KEGG: son:SO2799 lipoprotein, putative YP_001093623.1 PFAM: protein of unknown function DUF1538; KEGG: sfr:Sfri_2271 protein of unknown function DUF1538 YP_001093624.1 PFAM: protein of unknown function DUF1538; KEGG: sfr:Sfri_2272 protein of unknown function DUF1538 YP_001093625.1 KEGG: sfr:Sfri_2273 putative nitrogen regulatory protein P-II YP_001093626.1 PFAM: CBS domain containing protein; KEGG: sfr:Sfri_2274 putative signal-transduction protein with CBS domains YP_001093627.1 PFAM: glutaredoxin; KEGG: shm:Shewmr7_2487 glutaredoxin YP_001093628.1 PFAM: protein of unknown function DUF748; KEGG: she:Shewmr4_2416 protein of unknown function DUF748 YP_001093629.1 PFAM: ferredoxin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mxa:MXAN_6919 ferredoxin reductase YP_001093630.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_2038 hypothetical protein YP_001093631.1 KEGG: shm:Shewmr7_2484 hypothetical protein YP_001093632.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_1598 glyoxalase/bleomycin resistance protein/dioxygenase YP_001093633.1 PFAM: 5-carboxymethyl-2-hydroxymuconate isomerase; KEGG: vch:VC2669 5-carboxymethyl-2-hydroxymuconate delta isomerase, putative YP_001093634.1 SMART: extracellular solute-binding protein, family 3; KEGG: dvu:DVUA0150 bacterial extracellular solute-binding protein, family 3 YP_001093635.1 functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP YP_001093636.1 PFAM: peptidase M28; KEGG: sfr:Sfri_1604 peptidase M28 YP_001093637.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IIA; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: she:Shewmr4_2382 HAD-superfamily hydrolase, subfamily IIA YP_001093638.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_001093639.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_001093640.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_001093641.1 PFAM: Gluconate transporter; Citrate transporter; Na+/H+ antiporter NhaC; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: she:Shewmr4_2377 Na+/H+ antiporter NhaC YP_001093642.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_2448 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen YP_001093643.1 TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: son:SO3778 adenylate cyclase CyaB, putative YP_001093644.1 KEGG: sdn:Sden_0883 hypothetical protein YP_001093645.1 KEGG: shm:Shewmr7_0087 hypothetical protein YP_001093646.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_001093647.1 PFAM: OmpA/MotB domain protein; KEGG: shm:Shewmr7_2446 OmpA/MotB domain protein YP_001093648.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; peptidase S9A, prolyl oligopeptidase domain protein beta-propeller; KEGG: shm:Shewmr7_2445 prolyl oligopeptidase YP_001093649.1 TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2444 4-hydroxybenzoyl-CoA thioesterase YP_001093650.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: son:SO2751 MotA/TolQ/ExbB proton channel family protein YP_001093651.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: shm:Shewmr7_2442 biopolymer transport protein ExbD/TolR YP_001093652.1 PFAM: TolA family protein; KEGG: sfr:Sfri_1461 TolA family protein YP_001093653.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_001093654.1 TIGRFAM: OmpA domain protein; PFAM: OmpA/MotB domain protein; KEGG: shm:Shewmr7_2439 OmpA/MotB domain protein YP_001093655.1 PFAM: Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_2438 hypothetical protein YP_001093656.1 PFAM: porin; KEGG: she:Shewmr4_2365 hypothetical protein YP_001093657.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_001093658.1 PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: shm:Shewmr7_2435 type III restriction enzyme, res subunit YP_001093659.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_001093660.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_2361 multi-sensor hybrid histidine kinase YP_001093661.1 PFAM: fumarylacetoacetate (FAA) hydrolase; KEGG: vch:VCA1004 hypothetical protein YP_001093662.1 KEGG: dps:DP1720 probable chloramphenicol acetyltransferase YP_001093663.1 PFAM: FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2193 FAD dependent oxidoreductase YP_001093664.1 KEGG: pat:Patl_1355 hypothetical protein YP_001093665.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1785 transcriptional regulator, LysR family YP_001093666.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: shm:Shewmr7_2191 alcohol dehydrogenase, zinc-binding domain protein YP_001093667.1 PFAM: putative esterase; KEGG: sfr:Sfri_4058 carboxylesterase YP_001093668.1 PFAM: major facilitator superfamily MFS_1; KEGG: ppr:PBPRB0490 hypothetical protein YP_001093669.1 PFAM: secretion protein HlyD family protein; KEGG: ppr:PBPRB0491 hypothetical secretion protein YP_001093670.1 PFAM: regulatory protein, TetR; KEGG: ppr:PBPRB0492 hypothetical protein YP_001093671.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_1663 two component transcriptional regulator, LuxR family YP_001093672.1 PFAM: thioesterase superfamily protein; KEGG: son:SO2647 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_001093673.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_001093674.1 PFAM: protein of unknown function DUF299; KEGG: sfr:Sfri_2298 protein of unknown function DUF299 YP_001093675.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_001093676.1 PFAM: FAD linked oxidase domain protein; KEGG: son:SO2643 oxidoreductase, FAD-binding, putative YP_001093677.1 KEGG: sdn:Sden_2007 hypothetical protein YP_001093678.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_1670 transcriptional regulator, MarR family YP_001093679.1 KEGG: bpa:BPP2691 hypothetical protein YP_001093680.1 KEGG: shm:Shewmr7_1672 hypothetical protein YP_001093681.1 PFAM: Glu/Leu/Phe/Val dehydrogenase, C terminal; Glu/Leu/Phe/Val dehydrogenase, dimerisation region; KEGG: sdn:Sden_1823 Glu/Leu/Phe/Val dehydrogenase, dimerisation region YP_001093682.1 KEGG: shm:Shewmr7_1674 hypothetical protein YP_001093683.1 PFAM: Cupin 4 family protein; SMART: transcription factor jumonji, jmjC domain protein; KEGG: sfr:Sfri_2263 cupin 4 family protein YP_001093684.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_001093685.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_001093686.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_001093687.1 PFAM: NUDIX hydrolase; KEGG: son:SO2631 MutT/nudix family protein YP_001093688.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_2258 pseudouridine synthase, Rsu YP_001093689.1 KEGG: shm:Shewmr7_1681 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: Isocitrate dehydrogenase NADP-dependent, monomeric type YP_001093690.1 KEGG: shm:Shewmr7_1721 cold-shock DNA-binding domain protein; TIGRFAM: cold shock domain protein CspD; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein YP_001093691.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_001093692.1 KEGG: shm:Shewmr7_1723 ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase YP_001093693.1 stimulates the activities of the other two initiation factors, IF-2 and IF-3 YP_001093694.1 Conjugates Arg from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate YP_001093695.1 leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys YP_001093696.1 PFAM: 17 kDa surface antigen; KEGG: she:Shewmr4_1652 17 kDa surface antigen YP_001093697.1 KEGG: sfr:Sfri_2249 hypothetical protein YP_001093698.1 PFAM: protein of unknown function DUF34; KEGG: son:SO2621 conserved hypothetical protein TIGR00486 YP_001093699.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_001093700.1 KEGG: son:SO2618 ATP-binding protein, Mrp/Nbp35 family YP_001093701.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_001093702.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_001093703.1 PFAM: aminotransferase, class IV; KEGG: shm:Shewmr7_1734 aminotransferase, class IV YP_001093704.1 PFAM: aminodeoxychorismate lyase; KEGG: shm:Shewmr7_1735 aminodeoxychorismate lyase YP_001093705.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_001093706.1 TIGRFAM: DNA polymerase III, delta prime subunit; KEGG: son:SO2612 DNA polymerase III, delta prime subunit YP_001093707.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_1738 type IV pilus biogenesis protein PilZ YP_001093708.1 TIGRFAM: hydrolase, TatD family; PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_1739 hydrolase, TatD family YP_001093709.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_001093710.1 PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1666 nucleoside recognition domain protein YP_001093711.1 KEGG: shm:Shewmr7_2273 hypothetical protein YP_001093712.1 PFAM: diacylglycerol kinase; KEGG: sfr:Sfri_1483 diacylglycerol kinase YP_001093713.1 catalyzes the formation of a phosphodiester at the site of a single-strand break in duplex DNA YP_001093714.1 PFAM: low molecular weight phosphotyrosine protein phosphatase; KEGG: she:Shewmr4_2189 protein tyrosine phosphatase YP_001093715.1 essential GTPase; functions in ribosome assembly; binds a unique part of the 23S rRNA; interacts with ribosomal protein L25(Ctc) YP_001093716.1 PFAM: 2OG-Fe(II) oxygenase; KEGG: shm:Shewmr7_2262 2OG-Fe(II) oxygenase YP_001093717.1 this fusion consists of methionine sulfoxide B reductase at the N-terminus and A at the C-terminus; A and B are stereospecific enzymes that recognize the damaged produces of oxidative stress, S and R epimers of methionine sulfoxide, respectively; a fusion protein of these enzymes with thioredoxin provides protection against oxidative stress in Neisseria gonorrhoeae YP_001093718.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sdn:Sden_2303 sulphate transporter YP_001093719.1 TIGRFAM: ribonuclease, Rne/Rng family; PFAM: RNA binding S1 domain protein; KEGG: shm:Shewmr7_2475 ribonuclease, Rne/Rng family YP_001093720.1 KEGG: shm:Shewmr7_2474 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001093721.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sfr:Sfri_1492 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001093722.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-4 domain protein; KEGG: mca:MCA0985 sensory box protein YP_001093723.1 TIGRFAM: maf protein; PFAM: Maf family protein; KEGG: son:SO2782 maf protein, putative YP_001093724.1 PFAM: protein of unknown function DUF177; KEGG: son:SO2781 hypothetical protein YP_001093725.1 some L32 proteins have zinc finger motifs consisting of CXXC while others do not YP_001093726.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_001093727.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001093728.1 TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: acyl transferase domain protein; KEGG: she:Shewmr4_2397 malonyl CoA-acyl carrier protein transacylase YP_001093729.1 TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_2466 3-oxoacyl-(acyl-carrier-protein) reductase YP_001093730.1 carries the fatty acid chain in fatty acid biosynthesis YP_001093731.1 PFAM: beta-ketoacyl synthase; KEGG: son:SO2774 3-oxoacyl-(acyl-carrier-protein) synthase II YP_001093732.1 KEGG: she:Shewmr4_2393 hypothetical protein YP_001093733.1 PFAM: thioesterase superfamily protein; KEGG: son:SO2772 cytosolic long-chain acyl-CoA thioester hydrolase family protein YP_001093734.1 PFAM: carbohydrate kinase, FGGY; KEGG: rfr:Rfer_2334 carbohydrate kinase, FGGY YP_001093735.1 PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding; KEGG: she:Shewmr4_2391 6-phosphogluconate dehydrogenase, NAD-binding YP_001093736.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_001093737.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_001093738.1 KEGG: she:Shewmr4_2409 hypothetical protein YP_001093739.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_001093740.1 PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; KEGG: shm:Shewmr7_2477 cold-shock DNA-binding domain protein YP_001093741.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_1627 ABC transporter-related protein YP_001093742.1 KEGG: son:SO1866 hypothetical protein YP_001093743.1 PFAM: protein of unknown function DUF480; KEGG: she:Shewmr4_1554 protein of unknown function DUF480 YP_001093744.1 KEGG: she:Shewmr4_1555 hypothetical protein YP_001093745.1 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_001093746.1 PFAM: S-adenosylmethionine decarboxylase; KEGG: sfr:Sfri_1699 adenosylmethionine decarboxylase YP_001093747.1 catalyzes the formation of putrescine from agmatine YP_001093748.1 KEGG: sfr:Sfri_1702 pyridoxamine 5'-phosphate oxidase; TIGRFAM: pyridoxamine 5'-phosphate oxidase; PFAM: pyridoxamine 5'-phosphate oxidase-related, FMN-binding YP_001093749.1 KEGG: shm:Shewmr7_1661 hypothetical protein YP_001093750.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_001093751.1 KEGG: shm:Shewmr7_1804 L-serine dehydratase 1; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain YP_001093752.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_001093753.1 PFAM: protein of unknown function UPF0227; KEGG: shm:Shewmr7_1806 protein of unknown function UPF0227 YP_001093754.1 catalyzes the hydrolysis of acylphosphate YP_001093755.1 KEGG: sfr:Sfri_2400 hypothetical protein YP_001093756.1 KEGG: she:Shewmr4_1730 transcription-repair coupling factor; TIGRFAM: transcription-repair coupling factor; PFAM: helicase domain protein; transcription factor CarD; TRCF domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001093757.1 KEGG: shm:Shewmr7_1811 hypothetical protein YP_001093758.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1812 lipoprotein releasing system, transmembrane protein, LolC/E family YP_001093759.1 KEGG: son:SO2258 lipoprotein releasing system ATP-binding protein LolD; TIGRFAM: lipoprotein releasing system, ATP-binding protein; PFAM: ABC transporter-related protein; SMART: AAA ATPase YP_001093760.1 TIGRFAM: lipoprotein releasing system, transmembrane protein, LolC/E family; PFAM: protein of unknown function DUF214; KEGG: son:SO2259 lipoprotein releasing system transmembrane protein LolC, putative YP_001093761.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; CHASE domain protein; KEGG: vch:VCA0960 GGDEF family protein YP_001093762.1 KEGG: shm:Shewmr7_2494 hypothetical protein YP_001093763.1 TIGRFAM: DNA internalization-related competence protein ComEC/Rec2; PFAM: beta-lactamase domain protein; ComEC/Rec2-related protein; KEGG: she:Shewmr4_2423 DNA internalization-related competence protein ComEC/Rec2 YP_001093764.1 KEGG: shm:Shewmr7_2492 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; TIGRFAM: lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase YP_001093765.1 transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate YP_001093766.1 PFAM: protein of unknown function DUF343; KEGG: shm:Shewmr7_2490 protein of unknown function DUF343 YP_001093767.1 KEGG: sfr:Sfri_2385 Mn2+-dependent serine/threonine protein kinase YP_001093768.1 PFAM: Peptidase M11, gametolysin; KEGG: vpa:VPA0993 hypothetical protein YP_001093769.1 KEGG: vpa:VPA0992 hypothetical protein YP_001093770.1 PFAM: DSBA oxidoreductase; KEGG: vpa:VPA0994 hypothetical protein YP_001093771.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: shm:Shewmr7_3505 sigma54 specific transcriptional regulator, fis family YP_001093772.1 PFAM: beta-lactamase domain protein; KEGG: sdn:Sden_2195 beta-lactamase-like protein YP_001093773.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1627 acriflavin resistance protein YP_001093774.1 PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_1628 acriflavin resistance protein YP_001093775.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: biotin/lipoyl attachment domain-containing protein; secretion protein HlyD family protein; KEGG: she:Shewmr4_1629 efflux transporter, RND family, MFP subunit YP_001093776.1 type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH YP_001093777.1 PFAM: succinate dehydrogenase, cytochrome b subunit; KEGG: shm:Shewmr7_1706 succinate dehydrogenase, cytochrome b subunit YP_001093778.1 KEGG: she:Shewmr4_1632 conserved hypothetical succinate dehydrogenase, hydrophobic subunit YP_001093779.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_001093780.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_001093781.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_001093782.1 TIGRFAM: 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1711 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase YP_001093783.1 catalyzes the interconversion of succinyl-CoA and succinate YP_001093784.1 TIGRFAM: succinyl-CoA synthetase, alpha subunit; PFAM: CoA-binding domain protein; ATP-citrate lyase/succinyl-CoA ligase; KEGG: sdn:Sden_2180 succinyl-CoA synthetase, alpha subunit YP_001093785.1 PFAM: ferredoxin-dependent glutamate synthase; KEGG: cps:CPS_3206 glutamate synthase domain protein YP_001093786.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1715 GCN5-related N-acetyltransferase YP_001093787.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_001093788.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_001093789.1 KEGG: she:Shewmr4_1643 hypothetical protein YP_001093790.1 KEGG: ppr:PBPRB1101 hypothetical protein YP_001093791.1 PFAM: peptidase S51, dipeptidase E; KEGG: sbo:SBO_4042 peptidase E YP_001093792.1 PFAM: putative esterase; KEGG: sdn:Sden_0711 putative esterase YP_001093793.1 KEGG: sdn:Sden_1943 acetyl-CoA C-acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein YP_001093794.1 TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase; KEGG: she:Shewmr4_2596 methylmalonate-semialdehyde dehydrogenase YP_001093795.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2662 acyl-CoA dehydrogenase domain protein YP_001093796.1 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA YP_001093797.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2660 enoyl-CoA hydratase/isomerase YP_001093798.1 KEGG: son:SO1682 3-hydroxyisobutyrate dehydrogenase; TIGRFAM: 3-hydroxyisobutyrate dehydrogenase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; 6-phosphogluconate dehydrogenase, NAD-binding YP_001093799.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001093800.1 KEGG: shm:Shewmr7_2657 hypothetical protein YP_001093801.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: shm:Shewmr7_2656 peptidase S9, prolyl oligopeptidase active site domain protein YP_001093802.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2586 ABC transporter-related protein YP_001093803.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: cps:CPS_4956 cytosol aminopeptidase family protein YP_001093804.1 KEGG: pha:PSHAb0301 hypothetical protein YP_001093805.1 PFAM: regulatory protein, TetR; KEGG: vpa:VPA1562 putative transcriptional regulator YP_001093806.1 PFAM: HPP family protein+B94; KEGG: vpa:VPA1561 hypothetical protein YP_001093807.1 KEGG: tcx:Tcr_0379 diguanylate cyclase (GGDEF domain) with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001093808.1 PFAM: ribonuclease H; KEGG: sdn:Sden_0758 ribonuclease H YP_001093809.1 PFAM: protein of unknown function DUF1415; KEGG: sfr:Sfri_1353 protein of unknown function DUF1415 YP_001093810.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sdn:Sden_2232 lysine exporter protein (LysE/YggA) YP_001093811.1 PFAM: peptidase domain protein; Peptidase M9A, collagenase C-terminal domain protein; Peptidase M9, N-terminal domain; KEGG: son:SO0639 collagenase family YP_001093812.1 KEGG: shm:Shewmr7_2633 hypothetical protein YP_001093813.1 KEGG: vpa:VPA0219 hypothetical protein YP_001093814.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_0392 TonB-dependent receptor, plug YP_001093815.1 KEGG: shm:Shewmr7_2631 hypothetical protein YP_001093819.1 KEGG: sma:SAV3995 hypothetical protein YP_001093822.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_2629 protein of unknown function DUF6, transmembrane YP_001093823.1 PFAM: amino acid-binding ACT domain protein; KEGG: she:Shewmr4_2561 amino acid-binding ACT domain protein YP_001093824.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_2560 binding-protein-dependent transport systems inner membrane component YP_001093825.1 TIGRFAM: phosphate ABC transporter, inner membrane subunit PstA; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2626 phosphate ABC transporter, inner membrane subunit PstA YP_001093826.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_001093827.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_001093828.1 PFAM: Tetratricopeptide TPR_2 repeat protein YP_001093831.1 KEGG: hch:HCH_03896 hypothetical protein YP_001093832.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: vvu:VV21212 hypothetical protein YP_001093834.1 PFAM: protein of unknown function UPF0157; KEGG: cps:CPS_2738 hypothetical protein YP_001093835.1 SMART: HNH nuclease; KEGG: son:SO1738 hypothetical protein YP_001093836.1 PFAM: protein of unknown function DUF1289; KEGG: son:SO1739 hypothetical protein YP_001093837.1 KEGG: ppr:PBPRB1467 hypothetical methyl-accepting chemotaxis protein YP_001093838.1 KEGG: she:Shewmr4_2549 hypothetical protein YP_001093839.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_001093840.1 PFAM: alpha/beta hydrolase fold; KEGG: ppr:PBPRA1463 putative haloalkane dehalogenase YP_001093841.1 Catalyzes the specific recognition and activation of amino acids during peptide synthesis YP_001093842.1 PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: ppr:PBPRA1465 steroid dehydrogenase YP_001093843.1 PFAM: globin; KEGG: cvi:CV2936 probable bacterial hemoglobin YP_001093844.1 TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: shm:Shewmr7_2432 adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_001093845.1 KEGG: shm:Shewmr7_2431 biotin synthase; TIGRFAM: biotin synthase; PFAM: Radical SAM domain protein; biotin and thiamin synthesis associated; SMART: Elongator protein 3/MiaB/NifB YP_001093846.1 PFAM: aminotransferase, class I and II; aminotransferase class-III; KEGG: son:SO2739 8-amino-7-oxononanoate synthase YP_001093847.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_2357 biotin biosynthesis protein BioC YP_001093848.1 TIGRFAM: dethiobiotin synthase; KEGG: she:Shewmr4_2356 dethiobiotin synthase YP_001093849.1 putative metalloprotease YP_001093850.1 KEGG: shm:Shewmr7_2388 cytochrome c3 YP_001093851.1 PFAM: Curlin associated repeat protein; KEGG: sfr:Sfri_1515 curlin associated repeat protein YP_001093852.1 PFAM: regulatory protein, LuxR; KEGG: sfr:Sfri_1517 transcriptional regulator, LuxR family protein YP_001093853.1 KEGG: sfr:Sfri_1518 hypothetical protein YP_001093854.1 KEGG: sfr:Sfri_1519 curli production assembly/transport component CsgF precursor YP_001093855.1 PFAM: Curli production assembly/transport component CsgG; KEGG: sfr:Sfri_1520 curli production assembly/transport component CsgG YP_001093857.1 PFAM: histidine triad (HIT) protein; KEGG: sfr:Sfri_1522 histidine triad (HIT) protein YP_001093858.1 TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: son:SO2722 hypothetical protein YP_001093859.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_2382 thioesterase superfamily protein YP_001093860.1 PFAM: protein of unknown function DUF1425; KEGG: sfr:Sfri_1525 protein of unknown function DUF1425 YP_001093861.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2310 TonB-dependent receptor YP_001093862.1 KEGG: son:SO2714 hypothetical protein YP_001093863.1 TIGRFAM: nicotinamide mononucleotide transporter PnuC; PFAM: Nicotinamide mononucleotide transporter PnuC; KEGG: son:SO2713 transporter, putative YP_001093864.1 PFAM: Choline/ethanolamine kinase; aminoglycoside phosphotransferase; KEGG: sdn:Sden_2318 aminoglycoside phosphotransferase YP_001093865.1 PFAM: DoxX family protein; KEGG: sfr:Sfri_1531 DoxX family protein YP_001093866.1 PFAM: nitroreductase; KEGG: sfr:Sfri_1532 nitroreductase YP_001093867.1 PFAM: beta-lactamase domain protein; KEGG: vvy:VV2889 uncharacterized flavoprotein YP_001093868.1 KEGG: vvy:VV2888 methyl-accepting chemotaxis protein YP_001093869.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO2707 acetyltransferase, GNAT family YP_001093870.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1594 GCN5-related N-acetyltransferase YP_001093871.1 PFAM: GCN5-related N-acetyltransferase; KEGG: shm:Shewmr7_1595 GCN5-related N-acetyltransferase YP_001093872.1 KEGG: shm:Shewmr7_1596 hypothetical protein YP_001093873.1 KEGG: she:Shewmr4_1530 hypothetical protein YP_001093875.1 KEGG: vpa:VPA1301 hypothetical protein YP_001093876.1 KEGG: she:Shewmr4_2329 hypothetical protein YP_001093877.1 PFAM: Proprotein convertase, P; KEGG: she:Shewmr4_2330 hypothetical protein YP_001093879.1 KEGG: sfr:Sfri_2114 hypothetical protein YP_001093880.1 PFAM: hydrogenase expression/synthesis, HypA; KEGG: shm:Shewmr7_2165 hydrogenase nickel insertion protein HypA YP_001093881.1 TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: sfr:Sfri_2112 hydrogenase expression/formation protein HypE YP_001093882.1 TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: shm:Shewmr7_2163 hydrogenase expression/formation protein HypD YP_001093883.1 TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: son:SO2092 hydrogenase assembly chaperone hypC/hupF YP_001093884.1 TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: she:Shewmr4_1816 hydrogenase accessory protein HypB YP_001093885.1 TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: son:SO2094 hydrogenase maturation protein HypF YP_001093886.1 KEGG: she:Shewmr4_1818 hypothetical protein YP_001093887.1 TIGRFAM: hydrogenase maturation protease; hydrogenase expression/formation protein; PFAM: peptidase M52, hydrogen uptake protein; KEGG: shm:Shewmr7_2158 hydrogenase expression/formation protein YP_001093888.1 TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: cytochrome B561; KEGG: she:Shewmr4_1820 Ni/Fe-hydrogenase, b-type cytochrome subunit YP_001093889.1 PFAM: nickel-dependent hydrogenase, large subunit; KEGG: she:Shewmr4_1821 nickel-dependent hydrogenase, large subunit YP_001093890.1 KEGG: shm:Shewmr7_2155 hydrogenase (NiFe) small subunit HydA; TIGRFAM: hydrogenase (NiFe) small subunit HydA; PFAM: NADH ubiquinone oxidoreductase, 20 kDa subunit; Nickel-iron dehydrogenase small subunit, N-terminal domain protein YP_001093891.1 PFAM: CBS domain containing protein; KEGG: shm:Shewmr7_2139 putative signal transduction protein with CBS domains YP_001093892.1 KEGG: shm:Shewmr7_2138 ATP-dependent helicase HrpA; TIGRFAM: ATP-dependent helicase HrpA; PFAM: helicase domain protein; helicase-associated domain protein; protein of unknown function DUF1605; SMART: AAA ATPase; DEAD-like helicases-like YP_001093893.1 PFAM: periplasmic nitrate reductase NapE; KEGG: shm:Shewmr7_2137 periplasmic nitrate reductase NapE YP_001093894.1 PFAM: NapD family protein; KEGG: sdn:Sden_1496 NapD YP_001093895.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001093896.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shm:Shewmr7_2134 nitrate reductase cytochrome c-type subunit (NapB) YP_001093897.1 TIGRFAM: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family; PFAM: NapC/NirT cytochrome c domain protein; KEGG: shm:Shewmr7_2133 periplasmic nitrate (or nitrite) reductase C-type cytochrome, NapC/NirT family YP_001093898.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vfi:VFA0105 transcriptional regulator YP_001093899.1 KEGG: sfr:Sfri_2545 excinuclease ATPase subunit YP_001093900.1 with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit YP_001093901.1 TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: son:SO2279 acetolactate synthase large subunit YP_001093902.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_1831 drug resistance transporter, Bcr/CflA subfamily YP_001093903.1 KEGG: lpn:lpg2606 glutamine amidotransferase YP_001093904.1 KEGG: she:Shewmr4_1752 alkaline phosphatase YP_001093905.1 PFAM: Glutathione S-transferase, N-terminal domain; KEGG: ppr:PBPRB1270 hypothetical protein YP_001093906.1 PFAM: Rhodanese domain protein; KEGG: she:Shewmr4_1760 rhodanese domain protein YP_001093907.1 PFAM: regulatory protein, MarR; KEGG: she:Shewmr4_3435 transcriptional regulator, MarR family YP_001093908.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_0517 secretion protein HlyD family protein YP_001093909.1 KEGG: son:SO4050 hypothetical protein YP_001093910.1 PFAM: band 7 protein; KEGG: sdn:Sden_2191 band 7 protein YP_001093911.1 PFAM: protein of unknown function DUF107; KEGG: sdn:Sden_2190 protein of unknown function DUF107 YP_001093912.1 KEGG: son:SO2189 conserved hypothetical protein YP_001093913.1 PFAM: CreA family protein; KEGG: she:Shewmr4_2205 CreA family protein YP_001093914.1 catalyzes the formation of L-homocysteine from cystathionine YP_001093915.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_2203 periplasmic sensor signal transduction histidine kinase YP_001093916.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_1623 two component transcriptional regulator, winged helix family protein YP_001093917.1 PFAM: OmpA/MotB domain protein; KEGG: sfr:Sfri_1624 OmpA/MotB domain protein YP_001093918.1 PFAM: von Willebrand factor, type A; Vault protein inter-alpha-trypsin domain protein; SMART: Vault protein inter-alpha-trypsin, metazoa; KEGG: shm:Shewmr7_2277 vault protein inter-alpha-trypsin domain protein YP_001093919.1 TIGRFAM: sortase family protein; PFAM: peptidase C60, sortase A and B; KEGG: she:Shewmr4_2199 sortase family protein YP_001093920.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_2198 diguanylate cyclase YP_001093921.1 PFAM: Mammalian cell entry related domain protein; KEGG: she:Shewmr4_1667 mammalian cell entry related domain protein YP_001093922.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1743 paraquat-inducible protein A YP_001093923.1 PFAM: Paraquat-inducible protein A; KEGG: shm:Shewmr7_1744 paraquat-inducible protein A YP_001093924.1 PFAM: YebG family protein; KEGG: sdn:Sden_1719 YebG YP_001093925.1 PFAM: GAF domain protein; KEGG: son:SO2603 GAF domain-containing protein YP_001093926.1 affects solute and DNA transport through an unknown mechanism YP_001093927.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_001093928.1 TIGRFAM: aminopeptidase N; PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: shm:Shewmr7_1749 aminopeptidase N YP_001093929.1 KEGG: son:SO2598 hypothetical protein YP_001093930.1 PFAM: protein of unknown function DUF1302; KEGG: shm:Shewmr7_1751 protein of unknown function DUF1302 YP_001093931.1 PFAM: protein of unknown function DUF1329; KEGG: shm:Shewmr7_1752 protein of unknown function DUF1329 YP_001093932.1 KEGG: shm:Shewmr7_1753 BNR repeat protein YP_001093933.1 KEGG: shm:Shewmr7_1754 hypothetical protein YP_001093934.1 PFAM: NAD-glutamate dehydrogenase; KEGG: shm:Shewmr7_1755 NAD-glutamate dehydrogenase YP_001093935.1 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors YP_001093936.1 PFAM: protein of unknown function DUF1379; KEGG: son:SO2591 hypothetical protein YP_001093937.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_001093938.1 PFAM: glutaredoxin 2; KEGG: shm:Shewmr7_1608 glutaredoxin 2 YP_001093939.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_001093940.1 KEGG: shm:Shewmr7_1610 hypothetical protein YP_001093941.1 PFAM: ribosome modulation factor; KEGG: shm:Shewmr7_1611 ribosome modulation factor YP_001093942.1 catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP YP_001093943.1 KEGG: she:Shewmr4_1546 conserved hypothetical ATP-dependent protease YP_001093944.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sdn:Sden_1663 GntR-like protein YP_001093945.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_001093946.1 KEGG: pat:Patl_1420 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase YP_001093947.2 Catalyzes the conversion of citrate to isocitrate YP_001093948.1 TIGRFAM: putative AcnD-accessory protein PrpF; PFAM: protein of unknown function DUF453; KEGG: pen:PSEEN1906 hypothetical protein YP_001093949.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_001093950.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_001093951.1 KEGG: shm:Shewmr7_1616 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001093952.1 KEGG: she:Shewmr4_3520 methylation site containing protein YP_001093953.1 PFAM: Peptidoglycan-binding domain 1 protein; KEGG: sfr:Sfri_1440 peptidoglycan-binding domain 1 protein YP_001093954.1 PFAM: protein of unknown function DUF882; Peptidase M15A; KEGG: shm:Shewmr7_2145 protein of unknown function DUF882 YP_001093955.1 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response YP_001093956.1 PFAM: SpoVR family protein; KEGG: sdn:Sden_1636 SpoVR YP_001093957.1 PFAM: protein of unknown function DUF444; KEGG: shm:Shewmr7_1645 protein of unknown function DUF444 YP_001093958.1 PFAM: PrkA serine kinase; PrkA AAA domain protein; KEGG: son:SO2882 hypothetical Ser protein kinas YP_001093959.1 PFAM: manganese and iron superoxide dismutase; KEGG: sfr:Sfri_1747 superoxide dismutase YP_001093960.1 TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: shm:Shewmr7_1648 glutaredoxin-like protein YP_001093961.1 TIGRFAM: uracil-xanthine permease; PFAM: Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_1649 uracil-xanthine permease YP_001093962.1 KEGG: son:SO2878 hypothetical protein YP_001093963.1 controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP YP_001093964.1 KEGG: sfr:Sfri_1753 hypothetical protein YP_001093965.1 TIGRFAM: arsenate reductase; PFAM: arsenate reductase and related; KEGG: sfr:Sfri_1754 arsenate reductase YP_001093966.1 PFAM: peptidase M48, Ste24p; KEGG: she:Shewmr4_2347 peptidase M48, Ste24p YP_001093967.1 PFAM: SirA family protein; KEGG: she:Shewmr4_2346 SirA family protein YP_001093968.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_2417 protein of unknown function UPF0118 YP_001093969.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_001093970.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_2415 lysine exporter protein (LysE/YggA) YP_001093971.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: pat:Patl_2480 redoxin YP_001093972.1 PFAM: amino acid-binding ACT domain protein; KEGG: shm:Shewmr7_2413 amino acid-binding ACT domain protein YP_001093973.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_001093974.1 PFAM: NlpBDapX family lipoprotein; KEGG: shm:Shewmr7_2411 NlpBDapX family lipoprotein YP_001093975.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: pha:PSHAa1182 hypothetical protein ; GGDEF protein YP_001093976.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_2410 efflux transporter, RND family, MFP subunit YP_001093977.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_2409 acriflavin resistance protein YP_001093978.1 KEGG: shm:Shewmr7_1688 hypothetical protein YP_001093979.1 KEGG: sfr:Sfri_3720 hypothetical protein YP_001093980.1 KEGG: sdn:Sden_2135 hypothetical protein YP_001093981.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_001093982.1 PFAM: iron-containing alcohol dehydrogenase; KEGG: sdn:Sden_2133 iron-containing alcohol dehydrogenase YP_001093983.1 PFAM: aminotransferase, class V; DegT/DnrJ/EryC1/StrS aminotransferase; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: shm:Shewmr7_2125 DegT/DnrJ/EryC1/StrS aminotransferase YP_001093984.1 PFAM: carbonic anhydrase; KEGG: shm:Shewmr7_2124 carbonate dehydratase YP_001093985.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_2123 alpha/beta hydrolase fold YP_001093986.1 PFAM: peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins; KEGG: sfr:Sfri_1764 peptidase M15B and M15C, D,D-carboxypeptidase VanY/endolysins YP_001093987.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001093988.1 PFAM: arsenate reductase and related; KEGG: she:Shewmr4_1858 hypothetical protein YP_001093989.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_001093990.1 TIGRFAM: phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing enzyme; PEP-utilising enzyme, mobile region; PEP-utilising enzyme domain protein; KEGG: shm:Shewmr7_1842 phosphoenolpyruvate-protein phosphotransferase YP_001093991.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: shm:Shewmr7_1843 phosphocarrier, HPr family YP_001093992.1 KEGG: shm:Shewmr7_1844 hypothetical protein YP_001093993.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: shm:Shewmr7_1845 methyl-accepting chemotaxis sensory transducer YP_001093994.1 KEGG: son:SO2241 hypothetical protein YP_001093995.1 PFAM: regulatory protein, LacI; periplasmic binding protein/LacI transcriptional regulator; KEGG: shm:Shewmr7_1847 transcriptional regulator, LacI family YP_001093996.1 KEGG: vfi:VFA0016 DNA polymerase III epsilon subunit (3'-5' exonuclease); TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001093997.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001093998.1 KEGG: shm:Shewmr7_2109 glucan 1,4-alpha-glucosidase; TIGRFAM: glucan 1,4-alpha-glucosidase; PFAM: glycoside hydrolase 15-related YP_001093999.1 PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_1870 major facilitator superfamily MFS_1 YP_001094000.1 PFAM: peptidase M20; Fibronectin, type III domain protein; peptidase M28; KEGG: sfr:Sfri_3859 peptidase M28 YP_001094001.1 KEGG: sfr:Sfri_1777 alpha-glucosidase YP_001094002.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: hch:HCH_05473 hypothetical protein YP_001094003.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: vpa:VPA0296 putative oxidoreductase protein YP_001094004.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_1378 GCN5-related N-acetyltransferase YP_001094005.1 KEGG: sfr:Sfri_1916 hypothetical protein YP_001094006.1 KEGG: vch:VCA0414 hypothetical protein YP_001094007.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sfr:Sfri_2300 metal dependent phosphohydrolase YP_001094009.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: vpa:VP0903 RhlE YP_001094010.1 KEGG: hch:HCH_04427 hypothetical protein YP_001094011.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: sfr:Sfri_1784 alpha amylase, catalytic region YP_001094012.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: shm:Shewmr7_2211 alpha amylase, catalytic region YP_001094013.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_2134 TonB-dependent receptor YP_001094014.1 PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: son:SO2213 alpha-glucosidase YP_001094015.1 TIGRFAM: glucose/galactose transporter; PFAM: major facilitator superfamily MFS_1; KEGG: sfr:Sfri_1789 glucose/galactose transporter YP_001094016.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO2215 sun protein, putative YP_001094017.1 PFAM: SNF2-related protein; helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pae:PA0799 probable helicase YP_001094018.1 PFAM: protein of unknown function UPF0047; KEGG: sde:Sde_0527 alpha-1,6-glucosidases, pullulanase-type YP_001094019.1 KEGG: vpa:VPA0700 hypothetical protein YP_001094020.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_2154 redoxin domain protein YP_001094021.1 KEGG: son:SO2101 lipoprotein, putative YP_001094022.1 KEGG: sfr:Sfri_1126 hypothetical protein YP_001094023.1 PFAM: ApbE family lipoprotein; KEGG: shm:Shewmr7_2151 ApbE family lipoprotein YP_001094024.1 KEGG: vpa:VP1792 hypothetical protein YP_001094025.1 catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001094026.1 KEGG: sdn:Sden_1957 hypothetical protein YP_001094027.1 PFAM: NUDIX hydrolase; KEGG: she:Shewmr4_2126 NUDIX hydrolase YP_001094028.1 TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Anthranilate synthase component I and chorismate binding protein; Anthranilate synthase component I domain protein; KEGG: shm:Shewmr7_2201 para-aminobenzoate synthase, subunit I YP_001094029.1 TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; Fe-S type hydro-lyases tartrate/fumarate beta region; KEGG: shm:Shewmr7_2200 hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit YP_001094030.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; WD40 domain protein beta Propeller; KEGG: son:SO2223 peptidase, putative YP_001094031.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_4885 acetyltransferase, GNAT family YP_001094032.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: tbd:Tbd_2410 hypothetical protein YP_001094034.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: pat:Patl_3690 2OG-Fe(II) oxygenase YP_001094035.1 PFAM: iron-containing alcohol dehydrogenase; aldehyde dehydrogenase; KEGG: she:Shewmr4_1683 iron-containing alcohol dehydrogenase YP_001094036.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: shm:Shewmr7_1759 multiple antibiotic resistance (MarC)-related proteins YP_001094037.1 dGTPase family type 2 subfamily; presumably hydrolyzes dGTP to deoxyguanosine and triphosphate YP_001094038.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: son:SO2484 hypothetical protein YP_001094039.1 broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor YP_001094040.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_001094041.1 KEGG: sdn:Sden_1991 hypothetical protein YP_001094042.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001094043.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sdn:Sden_1989 CopG-like DNA-binding YP_001094044.1 KEGG: shm:Shewmr7_1941 hypothetical protein YP_001094045.1 PFAM: alpha/beta hydrolase fold; PGAP1 family protein; KEGG: shm:Shewmr7_1942 alpha/beta hydrolase fold YP_001094046.1 negative modulator of the initiation of chromosome replication YP_001094047.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_001094048.1 KEGG: sdn:Sden_1784 peptide methionine sulfoxide reductase; TIGRFAM: peptide methionine sulfoxide reductase; PFAM: Methionine sulfoxide reductase A YP_001094049.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_001094050.1 PFAM: dehydrogenase, E1 component; KEGG: shm:Shewmr7_1947 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) YP_001094051.1 PFAM: Transketolase, central region; Transketolase domain protein; KEGG: shm:Shewmr7_1948 transketolase, central region YP_001094052.1 PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein; KEGG: shm:Shewmr7_1949 catalytic domain of components of various dehydrogenase complexes YP_001094053.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_001094054.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Nitrate and nitrite sensing domain protein; KEGG: shm:Shewmr7_1760 methyl-accepting chemotaxis sensory transducer YP_001094055.1 PFAM: CopG domain protein DNA-binding domain protein; KEGG: sfr:Sfri_1091 hypothetical protein YP_001094056.1 TIGRFAM: alkylphosphonate utilization operon protein PhnA; PFAM: PhnA protein-like; KEGG: sdn:Sden_1233 alkylphosphonate utilization operon protein PhnA YP_001094057.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_001094058.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: ppr:PBPRA2923 hypothetical protein YP_001094059.1 KEGG: dde:Dde_3063 hypothetical protein YP_001094060.1 PFAM: protein of unknown function DUF885; KEGG: son:SO2570 lipoprotein, putative YP_001094061.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_2074 two component transcriptional regulator, winged helix family YP_001094062.1 PFAM: peptidase M14, carboxypeptidase A; KEGG: sfr:Sfri_2149 peptidase M14, carboxypeptidase A YP_001094063.1 KEGG: son:SO2423 hypothetical protein YP_001094064.1 PFAM: protein of unknown function DUF1315; KEGG: son:SO2422 hypothetical protein YP_001094065.1 converts asparagine to aspartate and ammonia YP_001094066.1 TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49; KEGG: son:SO2420 signal peptide peptidase SppA, 67K type YP_001094067.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: sfr:Sfri_2144 NADH:flavin oxidoreductase/NADH oxidase YP_001094068.1 KEGG: hne:HNE_0837 YCII domain protein YP_001094069.1 PFAM: ferredoxin; KEGG: sfr:Sfri_2135 ferredoxin YP_001094070.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_001094071.1 Catalyzes the rate-limiting step in dNTP synthesis YP_001094072.1 KEGG: she:Shewmr4_1917 HAD-superfamily hydrolase, subfamily IA, variant 1; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase YP_001094073.1 Involved in ubiquinone biosynthesis YP_001094074.1 TIGRFAM: DNA gyrase, A subunit; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal repeat, beta-propeller; KEGG: shm:Shewmr7_2059 DNA gyrase, A subunit YP_001094075.2 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_001094076.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001094077.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_001094078.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_001094079.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_001094080.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001094081.1 PFAM: protein of unknown function DUF1049; KEGG: sfr:Sfri_2121 protein of unknown function DUF1049 YP_001094082.1 KEGG: son:SO2399 hypothetical protein YP_001094083.1 type 1 subfamily; involved in last step of pyrimidine biosynthesis; converts orotidine 5'-phosphate to UMP and carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase YP_001094084.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: sdn:Sden_1758 short-chain dehydrogenase/reductase SDR YP_001094085.1 KEGG: son:SO2396 hypothetical protein YP_001094086.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: she:Shewmr4_1931 acyl-CoA dehydrogenase domain protein YP_001094087.1 KEGG: son:SO2394 penicillin-binding protein 4; TIGRFAM: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; PFAM: peptidase S13, D-Ala-D-Ala carboxypeptidase C YP_001094088.1 KEGG: shm:Shewmr7_2043 hypothetical protein YP_001094089.1 KEGG: son:SO2391 hypothetical protein YP_001094090.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_001094091.1 PFAM: DTW domain containing protein; KEGG: sdn:Sden_1780 hypothetical protein YP_001094092.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sfr:Sfri_2093 amidohydrolase YP_001094093.1 PFAM: beta-lactamase; KEGG: cps:CPS_1414 putative beta-lactamase YP_001094094.1 PFAM: regulatory protein, LuxR; response regulator receiver; KEGG: son:SO1416 DNA-binding response regulator YP_001094095.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO1417 sensor histidine kinase YP_001094096.1 PFAM: ApbE family lipoprotein; KEGG: son:SO1418 ApbE family protein YP_001094097.1 PFAM: FMN-binding domain protein; KEGG: son:SO1419 hypothetical protein YP_001094098.1 PFAM: porin, Gram-negative type; KEGG: son:SO1420 outer membrane porin, putative YP_001094099.1 KEGG: cps:CPS_0919 hypothetical protein YP_001094100.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_001094101.1 KEGG: ppr:PBPRB0364 putative ATP-dependent protease La-relatedprotein YP_001094102.1 KEGG: cps:CPS_3923 sensory box/GGDEF domain protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001094103.1 KEGG: vpa:VP1677 hypothetical protein YP_001094104.1 KEGG: vpa:VP1678 putative dienelactone hydrolase and related enzymes YP_001094105.1 KEGG: vpa:VP1679 hypothetical protein YP_001094106.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: pfl:PFL_2378 transcriptional regulator, AraC family YP_001094107.1 PFAM: phage integrase family protein; KEGG: shm:Shewmr7_1973 phage integrase family protein YP_001094108.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_1971 response regulator receiver modulated metal dependent phosphohydrolase YP_001094109.1 KEGG: sfr:Sfri_2009 hypothetical protein YP_001094110.1 CcoN; FixN YP_001094111.1 CcoO; FixO YP_001094112.1 PFAM: Cbb3-type cytochrome oxidase component; KEGG: sdn:Sden_1849 Cbb3-type cytochrome oxidase component YP_001094113.1 TIGRFAM: cytochrome c oxidase, cbb3-type, subunit III; PFAM: cytochrome c, class I; KEGG: shm:Shewmr7_1966 cytochrome c oxidase, cbb3-type, subunit III YP_001094114.1 KEGG: son:SO2360 hypothetical protein YP_001094115.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: son:SO2359 cation transport ATPase, E1-E2 family YP_001094116.1 TIGRFAM: cytochrome oxidase maturation protein, cbb3-type; PFAM: cytochrome oxidase maturation protein cbb3-type; KEGG: sdn:Sden_1845 cytochrome oxidase maturation protein, cbb3-type YP_001094117.1 KEGG: shm:Shewmr7_1962 hypothetical protein YP_001094118.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_001094119.1 with UspC and UspD is involved in resistance to UV irradiation YP_001094120.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_001094121.1 KEGG: she:Shewmr4_2017 hypothetical protein YP_001094122.1 KEGG: she:Shewmr4_2018 bax protein, putative YP_001094123.1 PFAM: protein of unknown function UPF0052 and CofD; KEGG: son:SO2351 hypothetical protein YP_001094124.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_001094125.1 catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent YP_001094126.1 KEGG: sfr:Sfri_1941 hypothetical protein YP_001094127.1 KEGG: son:SO2345 glyceraldehyde 3-phosphate dehydrogenase; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase YP_001094129.1 KEGG: vfi:VF0709 hypothetical protein YP_001094130.1 PFAM: FAD dependent oxidoreductase; KEGG: sfr:Sfri_0489 FAD dependent oxidoreductase YP_001094131.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_3397 acetyltransferase, GNAT family YP_001094132.1 KEGG: sdn:Sden_0075 hypothetical protein YP_001094133.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: vfi:VF1658 short chain dehydrogenase YP_001094134.1 KEGG: pat:Patl_3439 hypothetical protein YP_001094135.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sdn:Sden_1711 secretion protein HlyD YP_001094136.1 PFAM: acriflavin resistance protein; KEGG: sfr:Sfri_1929 acriflavin resistance protein YP_001094137.1 uncharacterized member of the major facilitator superfamily (MFS) YP_001094138.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_1974 transcriptional regulator, LysR family YP_001094139.1 PFAM: protein of unknown function UPF0005; KEGG: shm:Shewmr7_2003 protein of unknown function UPF0005 YP_001094140.1 PFAM: DsrE family protein; KEGG: she:Shewmr4_1972 DsrE family protein YP_001094141.1 PFAM: DsrE family protein; KEGG: shm:Shewmr7_2005 DsrE family protein YP_001094142.1 KEGG: sdn:Sden_1806 DsrH like protein YP_001094143.1 PFAM: DsrC family protein; KEGG: sdn:Sden_1805 DsrC-like protein YP_001094144.1 KEGG: son:SO2311 hypothetical protein YP_001094145.1 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001094146.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_001094147.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_2011 AAA ATPase, central domain protein YP_001094148.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: shm:Shewmr7_2012 outer membrane lipoprotein carrier protein LolA YP_001094149.1 PFAM: cell divisionFtsK/SpoIIIE; KEGG: she:Shewmr4_1963 cell divisionFtsK/SpoIIIE YP_001094150.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_001094151.1 TIGRFAM: alanine dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: shm:Shewmr7_2015 alanine dehydrogenase YP_001094152.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Shikimate/quinate 5-dehydrogenase; alanine dehydrogenase/PNT domain protein; KEGG: sfr:Sfri_1793 alanine dehydrogenase YP_001094153.1 TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_1959 thioredoxin reductase YP_001094154.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_001094155.1 PFAM: ribosomal protein L35; KEGG: sfr:Sfri_2026 ribosomal protein L35 YP_001094156.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_001094157.1 catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001094159.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: mca:MCA2986 pteridine reductase YP_001094160.1 KEGG: shm:Shewmr7_2023 hypothetical protein YP_001094161.1 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine YP_001094162.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: shm:Shewmr7_2025 MATE efflux family protein YP_001094164.1 PFAM: GCN5-related N-acetyltransferase; CoA-binding domain protein; KEGG: she:Shewmr4_2098 CoA-binding domain protein YP_001094165.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_1872 diguanylate cyclase YP_001094166.1 PFAM: sulfatase; protein of unknown function DUF1705; KEGG: she:Shewmr4_2103 sulfatase YP_001094167.1 PFAM: regulatory protein, MarR; KEGG: ppr:PBPRA1008 putative transcriptional regulator, MarR family YP_001094168.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_1868 cation diffusion facilitator family transporter YP_001094169.1 serine protease inhibitor, inhibits trypsin and other proteases YP_001094170.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_001094171.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_001094172.1 TIGRFAM: 6-phosphogluconolactonase; KEGG: son:SO2488 6-phosphogluconolactonase YP_001094173.1 catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate YP_001094174.1 Represses the expression of the zwf, eda, glp and gap YP_001094175.1 PFAM: pyruvate kinase; KEGG: son:SO2491 pyruvate kinase II YP_001094176.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001094177.1 PFAM: regulatory protein, TetR; KEGG: son:SO2493 transcriptional regulator, TetR family YP_001094178.1 PFAM: peptidase M2, peptidyl-dipeptidase A; KEGG: she:Shewmr4_2051 peptidyl-dipeptidase A YP_001094179.1 PFAM: Smr protein/MutS2; KEGG: shm:Shewmr7_1923 Smr protein/MutS2 YP_001094180.1 KEGG: shm:Shewmr7_1922 hypothetical protein YP_001094181.1 PFAM: SEC-C motif domain protein; KEGG: she:Shewmr4_2054 sec-C motif domain protein YP_001094182.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: she:Shewmr4_2055 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) YP_001094183.1 KEGG: shm:Shewmr7_1919 hypothetical protein YP_001094184.1 KEGG: she:Shewmr4_2057 hypothetical protein YP_001094185.1 PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: sdn:Sden_2013 pyridoxal-5'-phosphate-dependent enzyme, beta subunit YP_001094186.1 PFAM: Radical SAM domain protein; KEGG: shm:Shewmr7_1917 radical activating enzyme YP_001094187.1 TIGRFAM: exsB protein; PFAM: ExsB family protein; KEGG: she:Shewmr4_2059 ExsB protein YP_001094188.1 PFAM: Rhomboid family protein; KEGG: she:Shewmr4_2060 rhomboid family protein YP_001094189.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion YP_001094190.1 PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_2063 diguanylate cyclase/phosphodiesterase YP_001094191.1 TIGRFAM: electron transport complex, RnfABCDGE type, A subunit; PFAM: RnfA-Nqr electron transport subunit; KEGG: shm:Shewmr7_1911 electron transport complex, RnfABCDGE type, A subunit YP_001094192.1 TIGRFAM: electron transport complex, RnfABCDGE type, B subunit; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; Fe-S cluster domain protein; KEGG: shm:Shewmr7_1910 electron transport complex, RnfABCDGE type, B subunit YP_001094193.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_001094194.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_001094195.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_001094196.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_001094197.1 KEGG: she:Shewmr4_2070 endonuclease III; TIGRFAM: endonuclease III; PFAM: helix-hairpin-helix motif; HhH-GPD family protein; SMART: iron-sulfur cluster loop YP_001094198.1 KEGG: son:SO2044 lactoylglutathione lyase; TIGRFAM: lactoylglutathione lyase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001094199.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2416 TonB-dependent receptor YP_001094200.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_001094201.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_001094202.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_001094203.1 PFAM: protein of unknown function DUF28; KEGG: sdn:Sden_1886 protein of unknown function DUF28 YP_001094204.1 catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes YP_001094205.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; extracellular solute-binding protein, family 3; KEGG: shm:Shewmr7_2081 diguanylate cyclase YP_001094206.1 TIGRFAM: putative methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2082 putative methyltransferase YP_001094207.1 TIGRFAM: putative methyltransferase; PFAM: methyltransferase, putative; Methyltransferase type 11; Methyltransferase type 12; KEGG: she:Shewmr4_1895 putative methyltransferase YP_001094208.1 PFAM: protein of unknown function DUF785; KEGG: she:Shewmr4_1894 protein of unknown function DUF785 YP_001094209.1 KEGG: shm:Shewmr7_2085 gonadoliberin III-related protein YP_001094210.1 TIGRFAM: alpha-L-glutamate ligase-like protein; KEGG: she:Shewmr4_1892 alpha-L-glutamate ligase-like protein YP_001094211.1 KEGG: she:Shewmr4_1891 hypothetical protein YP_001094212.1 KEGG: shm:Shewmr7_2088 hypothetical protein YP_001094213.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_2089 transcriptional regulator, LysR family YP_001094214.1 KEGG: she:Shewmr4_1888 SrpA-related protein YP_001094215.1 KEGG: son:SO2439.2 hypothetical methyl-accepting chemotaxis protein YP_001094216.1 in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center YP_001094217.1 PFAM: thiazole biosynthesis family protein; KEGG: shm:Shewmr7_2093 thiazole biosynthesis family protein YP_001094218.1 TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: sdn:Sden_1773 thiamine biosynthesis protein ThiS YP_001094219.1 PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: son:SO2443 thiF protein, putative YP_001094220.1 KEGG: shm:Shewmr7_2096 thiamine-phosphate pyrophosphorylase; TIGRFAM: thiamine-phosphate pyrophosphorylase; phosphomethylpyrimidine kinase; PFAM: thiamine monophosphate synthase; Phosphomethylpyrimidine kinase type-1 YP_001094221.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_001094222.1 KEGG: shm:Shewmr7_2098 hypothetical protein YP_001094223.1 TIGRFAM: channel protein, hemolysin III family; PFAM: Hly-III family protein; KEGG: she:Shewmr4_1879 channel protein, hemolysin III family YP_001094224.1 PFAM: DTW domain containing protein; KEGG: cps:CPS_2423 hypothetical protein YP_001094225.1 KEGG: ilo:IL2566 DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; PFAM: PHP C-terminal domain protein; nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: phosphoesterase PHP domain protein YP_001094226.1 KEGG: bxe:Bxe_A3165 hypothetical protein YP_001094227.1 KEGG: tbd:Tbd_0830 hypothetical protein YP_001094228.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001094229.1 PFAM: major facilitator superfamily MFS_1; KEGG: cps:CPS_1452 hypothetical protein YP_001094230.1 PFAM: methylated-DNA-[protein]-cysteine S-methyltransferase; KEGG: shm:Shewmr7_2220 methylated-DNA-(protein)-cysteine S-methyltransferase YP_001094231.1 KEGG: shm:Shewmr7_2221 hypothetical protein YP_001094232.1 PFAM: glutamine amidotransferase, class-II; KEGG: she:Shewmr4_2145 glutamine amidotransferase, class-II YP_001094233.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001094234.1 PFAM: sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2224 sodium/hydrogen exchanger YP_001094235.1 KEGG: shm:Shewmr7_2233 hypothetical protein YP_001094236.1 KEGG: shm:Shewmr7_2234 DNA polymerase III, epsilon subunit; TIGRFAM: DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease YP_001094237.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_001094238.1 KEGG: son:SO2562 hypothetical protein YP_001094239.1 PFAM: beta-lactamase domain protein; KEGG: shm:Shewmr7_2238 hydroxyacylglutathione hydrolase YP_001094240.1 PFAM: Peptidoglycan-binding LysM; Lytic transglycosylase, catalytic; MLTD_N domain protein; KEGG: she:Shewmr4_2162 MLTD_N domain protein YP_001094241.1 PFAM: AsmA family protein; KEGG: she:Shewmr4_2164 AsmA family protein YP_001094242.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001094243.1 KEGG: son:SO2569 hypothetical protein YP_001094244.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; Cache, type 2 domain protein; KEGG: sfr:Sfri_2212 methyl-accepting chemotaxis sensory transducer YP_001094245.1 KEGG: vvy:VV2031 hypothetical protein YP_001094246.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: sfr:Sfri_3387 diguanylate cyclase YP_001094247.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_001094248.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_001094249.1 PFAM: protein of unknown function DUF195; KEGG: shm:Shewmr7_1864 protein of unknown function DUF195 YP_001094250.1 PFAM: Lytic transglycosylase, catalytic; KEGG: sfr:Sfri_2529 lytic transglycosylase, catalytic YP_001094251.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1856 ATPase associated with various cellular activities, AAA_3 YP_001094252.1 PFAM: protein of unknown function DUF58; KEGG: shm:Shewmr7_1855 protein of unknown function DUF58 YP_001094253.1 PFAM: transglutaminase domain protein; KEGG: she:Shewmr4_1776 transglutaminase domain protein YP_001094254.1 TIGRFAM: exodeoxyribonuclease V, gamma subunit; PFAM: Exodeoxyribonuclease V, RecC subunit; KEGG: she:Shewmr4_1775 exodeoxyribonuclease V, gamma subunit YP_001094255.1 TIGRFAM: exodeoxyribonuclease V, beta subunit; PFAM: UvrD/REP helicase; KEGG: she:Shewmr4_1774 exodeoxyribonuclease V, beta subunit YP_001094256.1 TIGRFAM: exodeoxyribonuclease V, alpha subunit; KEGG: she:Shewmr4_1773 exodeoxyribonuclease V, alpha subunit YP_001094258.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_001094259.1 PFAM: heat shock protein Hsp20; KEGG: son:SO2277 16 kDa heat shock protein A YP_001094260.1 catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides YP_001094261.1 PFAM: phospholipase/Carboxylesterase; KEGG: sdn:Sden_2138 carboxylesterase YP_001094262.1 PFAM: Glutathione S-transferase, C-terminal domain; KEGG: ppr:PBPRA2730 putative glutathione S-transferase YP_001094263.1 KEGG: vch:VCA0579 hypothetical protein YP_001094264.1 PFAM: peptidylprolyl isomerase, FKBP-type; KEGG: sdn:Sden_2140 peptidylprolyl isomerase, FKBP-type YP_001094265.1 KEGG: shm:Shewmr7_1781 hypothetical protein YP_001094266.1 TIGRFAM: lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein; KEGG: she:Shewmr4_2269 lytic murein transglycosylase YP_001094267.1 KEGG: sdn:Sden_2142 hypothetical protein YP_001094268.1 KEGG: son:SO1990 hypothetical protein YP_001094269.1 PFAM: response regulator receiver; CheW domain protein; KEGG: son:SO1989 chemotaxis protein CheV YP_001094270.1 PFAM: MscS Mechanosensitive ion channel; KEGG: vvy:VVA1412 small-conductance mechanosensitive channel YP_001094271.1 KEGG: shm:Shewmr7_2349 hypothetical protein YP_001094272.1 KEGG: she:Shewmr4_2279 hypothetical protein YP_001094273.1 PFAM: protein of unknown function DUF307; KEGG: son:SO1977 hypothetical protein YP_001094274.1 KEGG: she:Shewmr4_2283 conserved hypothetical ABC transporter protein YP_001094275.1 KEGG: shm:Shewmr7_2356 integral membrane protein TerC YP_001094276.1 KEGG: she:Shewmr4_2286 hypothetical protein YP_001094277.1 KEGG: son:SO1968 hypothetical protein YP_001094278.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO1965 transcriptional regulator, LysR family YP_001094279.1 PFAM: homogentisate 1,2-dioxygenase; KEGG: shm:Shewmr7_2363 homogentisate 1,2-dioxygenase YP_001094280.1 KEGG: sdn:Sden_2163 4-hydroxyphenylpyruvate dioxygenase; TIGRFAM: 4-hydroxyphenylpyruvate dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase YP_001094281.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfr:Sfri_2328 lysine exporter protein (LysE/YggA) YP_001094282.1 PFAM: protein of unknown function DUF482; KEGG: sdn:Sden_1656 protein of unknown function DUF482 YP_001094283.1 KEGG: she:Shewmr4_2297 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase YP_001094284.1 TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; KEGG: shm:Shewmr7_1220 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor YP_001094285.1 KEGG: she:Shewmr4_2301 dipeptidase, putative; TIGRFAM: dipeptidase, putative; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001094286.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_2302 peptidyl-dipeptidase DCP YP_001094287.1 periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate YP_001094288.1 PFAM: protein of unknown function DUF938; Methyltransferase type 11; KEGG: sfr:Sfri_2306 protein of unknown function DUF938 YP_001094289.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sfr:Sfri_2744 acyl-CoA dehydrogenase domain protein YP_001094290.1 PFAM: Aldose 1-epimerase; KEGG: shm:Shewmr7_2460 aldose 1-epimerase YP_001094291.1 KEGG: she:Shewmr4_1791 hypothetical protein YP_001094292.1 KEGG: son:SO2063 hypothetical protein YP_001094293.1 PFAM: uncharacterized conserved protein UCP025560; KEGG: shm:Shewmr7_2188 uncharacterized conserved protein UCP025560 YP_001094294.1 KEGG: pat:Patl_2065 UspA YP_001094295.1 PFAM: PKD domain containing protein; Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_1534 PKD domain containing protein YP_001094296.1 PFAM: peptidase T2, asparaginase 2; KEGG: shm:Shewmr7_2140 peptidase T2, asparaginase 2 YP_001094297.1 PFAM: surface antigen (D15); KEGG: she:Shewmr4_1836 surface antigen (D15) YP_001094298.1 PFAM: protein of unknown function DUF490; KEGG: son:SO2113 hypothetical protein YP_001094299.1 Multifunctional regulator of fatty acid metabolism YP_001094300.1 involved in regulation of intracellular pH under alkaline conditions YP_001094301.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_001094304.1 KEGG: mlo:msl8646 hypothetical protein YP_001094305.1 KEGG: cte:CT0680 hypothetical protein YP_001094306.1 PFAM: protein of unknown function UPF0153; KEGG: sdn:Sden_1632 uncharacterized conserved protein UCP006173 YP_001094307.1 KEGG: shm:Shewmr7_2248 putative transglycosylase YP_001094308.1 PFAM: protein of unknown function DUF709; KEGG: sdn:Sden_1630 protein of unknown function DUF709 YP_001094309.1 blocks the formation of polar Z-ring septums YP_001094310.1 TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: shm:Shewmr7_2251 septum site-determining protein MinD YP_001094311.1 TIGRFAM: cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; KEGG: sfr:Sfri_1735 cell division topological specificity factor MinE YP_001094312.1 TIGRFAM: ribonuclease D; PFAM: HRDC domain protein; 3'-5' exonuclease; KEGG: son:SO2580 ribonuclease D YP_001094313.1 Activates fatty acids by binding to coenzyme A YP_001094314.1 KEGG: shm:Shewmr7_2255 alpha/beta hydrolase fold YP_001094315.1 KEGG: sdn:Sden_1623 hypothetical protein YP_001094316.1 KEGG: son:SO2584 hypothetical protein YP_001094317.1 KEGG: sdn:Sden_1621 hypothetical protein YP_001094318.1 PFAM: peptidase M22, glycoprotease; KEGG: son:SO2586 hypothetical protein YP_001094319.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_2651 protein of unknown function DUF6, transmembrane YP_001094320.1 PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pha:PSHAb0118 respiratory NADH dehydrogenase II YP_001094321.1 SMART: helicase c2; DEAD-like helicases-like; KEGG: shm:Shewmr7_2172 helicase C2 YP_001094322.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_001094323.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_001094324.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_001094325.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_001094326.1 with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide YP_001094327.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_001094328.1 catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase YP_001094329.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_001094330.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sde:Sde_0667 response regulator receiver domain protein (CheY-like) YP_001094331.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: hch:HCH_01757 response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain YP_001094332.1 PFAM: TPR repeat-containing protein; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: pha:PSHAa0111 hypothetical protein YP_001094333.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sdn:Sden_3290 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001094334.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; PKD domain containing protein; Proprotein convertase, P; KEGG: sdn:Sden_3093 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001094335.1 PFAM: Proprotein convertase, P; KEGG: pha:PSHAb0200 putative secreted serine protease, subtilisin family, possibly excreted YP_001094336.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_001094337.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_1525 peptidyl-dipeptidase DCP YP_001094338.1 Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA YP_001094339.1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control YP_001094340.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily YP_001094341.1 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily YP_001094342.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2170 methyl-accepting chemotaxis sensory transducer YP_001094343.1 TIGRFAM: PAS sensor protein; PFAM: histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; KEGG: son:SO2889 sensory box histidine kinase YP_001094344.1 PFAM: protein of unknown function DUF785; KEGG: she:Shewmr4_1564 protein of unknown function DUF785 YP_001094345.1 KEGG: she:Shewmr4_1563 hypothetical protein YP_001094347.1 KEGG: son:SO2891 hypothetical protein YP_001094348.1 PFAM: YceI family protein; KEGG: son:SO2893 hypothetical protein YP_001094349.1 catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity YP_001094350.1 catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation YP_001094351.1 PFAM: Ig domain protein, group 1 domain protein; KEGG: sdn:Sden_2330 Ig-like, group 1 YP_001094352.1 PFAM: sodium:dicarboxylate symporter; KEGG: shm:Shewmr7_1657 sodium:dicarboxylate symporter YP_001094353.1 PFAM: PfkB domain protein; KEGG: shm:Shewmr7_2319 inosine kinase YP_001094354.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_001094355.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_001094356.1 PFAM: Thioredoxin domain; KEGG: shm:Shewmr7_2322 thioredoxin domain YP_001094357.1 molecular chaperone YP_001094358.1 involved in a recombinational process of DNA repair, independent of the recBC complex YP_001094359.1 PFAM: conserved hypothetical protein 103; KEGG: sdn:Sden_2380 conserved hypothetical protein 103 YP_001094360.1 KEGG: shm:Shewmr7_2326 DNA polymerase III, subunits gamma and tau; TIGRFAM: DNA polymerase III, subunits gamma and tau; PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase YP_001094361.1 KEGG: sdn:Sden_2382 adenine phosphoribosyltransferase; TIGRFAM: adenine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001094362.1 PFAM: protein of unknown function DUF454; KEGG: shm:Shewmr7_2328 protein of unknown function DUF454 YP_001094363.1 KEGG: shm:Shewmr7_2329 hypothetical protein YP_001094364.1 KEGG: sfr:Sfri_2411 hypothetical protein YP_001094365.1 PFAM: protein of unknown function DUF692; Xylose isomerase domain protein TIM barrel; KEGG: sfr:Sfri_2412 protein of unknown function DUF692 YP_001094366.1 KEGG: sfr:Sfri_2413 hypothetical protein YP_001094367.1 PFAM: dihydrouridine synthase, DuS; KEGG: cps:CPS_0906 NifR3/Smm1 family protein YP_001094368.1 KEGG: shm:Shewmr7_2334 transcriptional regulators, TraR/DksA family YP_001094369.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2335 TonB-dependent receptor YP_001094370.1 KEGG: son:SO2936 hypothetical protein YP_001094371.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_1533 pseudouridine synthase, Rsu YP_001094372.1 TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB; KEGG: shm:Shewmr7_1532 putative transcriptional regulator YP_001094373.1 PFAM: chromosome segregation and condensation protein ScpA; KEGG: she:Shewmr4_1465 chromosome segregation and condensation protein ScpA YP_001094374.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: shm:Shewmr7_1530 SUA5/YciO/YrdC/YwlC family protein YP_001094375.1 PFAM: PHP C-terminal domain protein; SMART: phosphoesterase PHP domain protein; KEGG: sdn:Sden_2449 PHP-like protein YP_001094376.1 with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine YP_001094377.1 TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity YP_001094378.1 Catalyzes the conversion of N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001094379.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_001094380.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_001094381.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_001094382.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: sdn:Sden_0759 HAD-superfamily hydrolase, subfamily IA, variant 1 YP_001094383.1 PFAM: NADH:ubiquinone oxidoreductase complex I intermediate-associated protein 30; KEGG: sfr:Sfri_3246 hypothetical protein YP_001094384.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sfr:Sfri_1823 metal dependent phosphohydrolase YP_001094385.1 Involved in cell division; probably involved in intracellular septation YP_001094386.1 unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity YP_001094387.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_001094388.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_1507 methyl-accepting chemotaxis sensory transducer YP_001094389.1 PFAM: protein of unknown function DUF1097; KEGG: son:SO3047 hypothetical protein YP_001094390.1 PFAM: aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead; aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding; KEGG: shm:Shewmr7_1505 twin-arginine translocation pathway signal YP_001094391.1 PFAM: ferredoxin; [2Fe-2S]-binding domain protein; KEGG: sfr:Sfri_1414 (2Fe-2S)-binding domain protein YP_001094392.1 KEGG: sdn:Sden_2225 hypothetical protein YP_001094393.1 PFAM: protein of unknown function DUF182; KEGG: sdn:Sden_2226 protein of unknown function DUF182 YP_001094394.1 PFAM: beta-lactamase domain protein; KEGG: son:SO3054 metallo-beta-lactamase family protein YP_001094395.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO3055 proline iminopeptidase YP_001094396.1 KEGG: she:Shewmr4_2330 hypothetical protein YP_001094398.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein YP_001094399.1 SMART: AAA ATPase; KEGG: cte:CT0993 hypothetical protein YP_001094400.1 PFAM: Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; KEGG: sfr:Sfri_1824 extradiol ring-cleavage dioxygenase, class III enzyme, subunit B YP_001094401.1 KEGG: nwi:Nwi_2675 glutathione S-transferase YP_001094402.1 PFAM: DoxX family protein; KEGG: son:SO3319 hypothetical protein YP_001094403.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: par:Psyc_1132 probable transcriptional regulator, LysR family YP_001094404.1 KEGG: son:SO3056 tetraheme cytochrome c YP_001094405.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: son:SO3057 Pal/histidase family protein YP_001094406.1 TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: son:SO3058 flavocytochrome c flavin subunit, putative YP_001094407.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: son:SO3059 formate hydrogenlyase transcriptional activator, putative YP_001094408.1 PFAM: porin, Gram-negative type; KEGG: son:SO3060 outer membrane porin, putative YP_001094409.1 KEGG: ppr:PBPRA1377 hypothetical protein YP_001094410.1 TIGRFAM: UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: vpa:VPA0879 UDP-glucose 4-epimerase YP_001094411.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pha:PSHAa1768 sodium/hexose cotransport protein YP_001094412.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: pha:PSHAa1769 galactokinase YP_001094413.1 KEGG: pha:PSHAa1770 galactose-1-phosphate uridylyltransferase; TIGRFAM: galactose-1-phosphate uridylyltransferase; PFAM: galactose-1-phosphate uridyl transferase domain protein YP_001094414.1 PFAM: Glycosyl hydrolase family 98, putative carbohydrate binding module; KEGG: dge:Dgeo_2665 glycosyl hydrolase family 98, putative carbohydrate binding module YP_001094415.1 PFAM: protein of unknown function DUF606; KEGG: cvi:CV3484 hypothetical protein YP_001094416.1 PFAM: protein of unknown function DUF606; KEGG: son:SO0370 hypothetical protein YP_001094417.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0340 transcriptional regulator, LysR family YP_001094418.1 PFAM: tryptophan halogenase; KEGG: shm:Shewmr7_3023 tryptophan halogenase YP_001094420.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: msu:MS1229 AraC protein YP_001094421.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2604 TonB-dependent receptor YP_001094422.1 PFAM: PEGA domain protein YP_001094423.1 KEGG: sde:Sde_2360 putative alpha-glucosidase YP_001094424.1 decatenates replicating daughter chromosomes YP_001094426.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_2991 methyl-accepting chemotaxis sensory transducer YP_001094427.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_001094428.1 PFAM: Colicin V production protein; KEGG: shm:Shewmr7_1494 colicin V production protein YP_001094429.1 PFAM: Sporulation domain protein; KEGG: shm:Shewmr7_1493 sporulation domain protein YP_001094430.1 TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: sfr:Sfri_1396 FolC bifunctional protein YP_001094431.1 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability YP_001094432.1 KEGG: she:Shewmr4_1425 hypothetical protein YP_001094433.1 KEGG: shm:Shewmr7_1489 aspartate-semialdehyde dehydrogenase; TIGRFAM: aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, NAD - binding; Semialdehyde dehydrogenase, dimerisation region YP_001094434.1 PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: she:Shewmr4_1423 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region YP_001094435.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_001094436.1 PFAM: protein of unknown function DUF528; KEGG: shm:Shewmr7_1826 protein of unknown function DUF528 YP_001094437.1 TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin; KEGG: shm:Shewmr7_1824 ferredoxin, 2Fe-2S type, ISC system YP_001094438.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_001094439.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_001094440.1 TIGRFAM: iron-sulfur cluster assembly accessory protein; iron-sulfur cluster assembly protein IscA; PFAM: HesB/YadR/YfhF-family protein; KEGG: shm:Shewmr7_1821 iron-sulfur cluster assembly protein IscA YP_001094441.1 TIGRFAM: FeS cluster assembly scaffold IscU; PFAM: nitrogen-fixing NifU domain protein; KEGG: shm:Shewmr7_1820 FeS cluster assembly scaffold IscU YP_001094442.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_001094443.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; iron-sulfur cluster assembly transcription factor IscR; PFAM: protein of unknown function UPF0074; KEGG: shm:Shewmr7_1818 transcriptional regulator, BadM/Rrf2 family YP_001094444.1 TIGRFAM: serine O-acetyltransferase; KEGG: she:Shewmr4_1737 serine O-acetyltransferase YP_001094445.1 TIGRFAM: RNA methyltransferase, TrmH family, group 1; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: shm:Shewmr7_1816 RNA methyltransferase, TrmH family, group 1 YP_001094446.1 PFAM: inositol monophosphatase; KEGG: shm:Shewmr7_1815 inositol-phosphate phosphatase YP_001094447.1 PFAM: NnrS family protein; KEGG: shm:Shewmr7_2495 NnrS family protein YP_001094448.1 PFAM: phosphate-starvation-inducible E; KEGG: shm:Shewmr7_2496 phosphate-starvation-inducible E YP_001094449.1 PFAM: type IV pilus assembly PilZ; KEGG: shm:Shewmr7_2497 type IV pilus assembly PilZ YP_001094450.1 KEGG: sdn:Sden_1451 hypothetical protein YP_001094451.1 KEGG: son:SO2809 RepA domain protein YP_001094452.1 KEGG: sfr:Sfri_1783 hypothetical protein YP_001094453.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase internal region; 5TM Receptors of the LytS-YhcK type, transmembrane region; KEGG: shm:Shewmr7_2501 signal transduction histidine kinase, LytS YP_001094454.1 unknown function; when overproduced it confers drug-resistance YP_001094455.1 PFAM: carbon starvation protein CstA; KEGG: shm:Shewmr7_2503 carbon starvation protein CstA YP_001094456.1 PFAM: YaeQ family protein; KEGG: shm:Shewmr7_1454 YaeQ family protein YP_001094457.1 TIGRFAM: siroheme synthase; KEGG: son:SO3108 precorrin-2 oxidase / ferrochelatase YP_001094458.1 KEGG: shm:Shewmr7_1451 hypothetical protein YP_001094459.1 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF YP_001094460.1 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane YP_001094461.1 TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: son:SO3112 preprotein translocase, YajC subunit YP_001094462.1 Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr) YP_001094463.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_001094464.1 PFAM: protein of unknown function DUF479; KEGG: sfr:Sfri_2704 protein of unknown function DUF479 YP_001094465.1 PFAM: Redoxin domain protein; KEGG: shm:Shewmr7_1443 redoxin domain protein YP_001094466.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sdn:Sden_1366 sigma-54 factor, interaction region YP_001094467.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sdn:Sden_1365 ATP-binding region, ATPase-like protein YP_001094468.1 KEGG: sdn:Sden_1364 hypothetical protein YP_001094469.1 KEGG: sfr:Sfri_2525 hypothetical protein YP_001094470.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: sdn:Sden_1897 binding-protein-dependent transport systems inner membrane component YP_001094471.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: cps:CPS_3310 putative phosphonate ABC transporter, ATP-binding protein YP_001094472.1 TIGRFAM: phosphonate ABC transporter, periplasmic phosphonate-binding protein; KEGG: sfr:Sfri_2485 phosphonate ABC transporter, periplasmic phosphonate-binding protein YP_001094473.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: shm:Shewmr7_1655 two component transcriptional regulator, winged helix family YP_001094474.1 PFAM: ATP-binding region, ATPase domain protein domain protein; KEGG: she:Shewmr4_1579 periplasmic sensor signal transduction histidine kinase YP_001094475.1 PFAM: 2OG-Fe(II) oxygenase; SMART: Prolyl 4-hydroxylase, alpha subunit; KEGG: son:SO1944 hypothetical protein YP_001094476.1 KEGG: shm:Shewmr7_1652 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001094478.1 TIGRFAM: magnesium and cobalt transport protein CorA; PFAM: Mg2+ transporter protein, CorA family protein; KEGG: son:SO1941 magnesium and cobalt transport protein CorA YP_001094479.1 KEGG: sfr:Sfri_3226 hypothetical protein YP_001094480.1 KEGG: sfr:Sfri_0786 hypothetical protein YP_001094481.1 PFAM: Patatin; KEGG: she:Shewmr4_2385 patatin YP_001094482.1 Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate YP_001094483.1 PFAM: peptidase M24; peptidase M24B, X-Pro dipeptidase/aminopeptidase domain protein; KEGG: mca:MCA2770 xaa-pro aminopeptidase YP_001094484.1 PFAM: Uracil-DNA glycosylase superfamily; KEGG: dar:Daro_1297 hypothetical protein YP_001094485.1 PFAM: FAD dependent oxidoreductase; KEGG: hch:HCH_03166 glycine/D-amino acid oxidases (deaminating) YP_001094486.1 PFAM: proline racemase; KEGG: cps:CPS_1453 putative proline racemase YP_001094487.1 KEGG: cps:CPS_1449 dihydrodipicolinate synthetase family protein; TIGRFAM: dihydrodipicolinate synthase; PFAM: dihydrodipicolinate synthetase YP_001094488.1 PFAM: proline racemase; KEGG: hch:HCH_03167 proline racemase YP_001094489.1 PFAM: aldehyde dehydrogenase; KEGG: csa:Csal_1140 aldehyde dehydrogenase YP_001094490.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: she:Shewmr4_1521 transcriptional regulator, GntR family YP_001094491.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs; in Pseudomonas this protein is involved in quinolone signal biosynthesis YP_001094492.1 KEGG: shm:Shewmr7_1586 hypothetical protein YP_001094493.1 PFAM: Exonuclease, RNase T and DNA polymerase III; SMART: Exonuclease; KEGG: she:Shewmr4_1516 exonuclease, RNase T and DNA polymerase III YP_001094494.1 PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: son:SO2856 CBS domain protein YP_001094495.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: sdn:Sden_1373 methyltransferase type 12 YP_001094496.1 PFAM: Na+/solute symporter; KEGG: sfr:Sfri_1547 Na+/solute symporter YP_001094497.1 KEGG: shm:Shewmr7_1580 hypothetical protein YP_001094498.1 PFAM: DSBA oxidoreductase; KEGG: she:Shewmr4_1512 DsbA oxidoreductase YP_001094499.1 KEGG: sfr:Sfri_2458 NAD-dependent epimerase/dehydratase YP_001094500.1 KEGG: she:Shewmr4_1510 metal dependent phosphohydrolase; TIGRFAM: metal dependent phophohydrolase; PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region YP_001094501.1 KEGG: son:SO2863 hypothetical protein YP_001094502.1 KEGG: shm:Shewmr7_1575 DNA ligase, NAD-dependent; TIGRFAM: DNA ligase, NAD-dependent; PFAM: BRCT domain protein; zinc-finger, NAD-dependent DNA ligase C4-type; NAD-dependent DNA ligase, OB-fold; NAD-dependent DNA ligase, adenylation; SMART: NAD-dependent DNA ligase-like YP_001094503.1 TIGRFAM: cell division protein ZipA; PFAM: ZipA, C-terminal FtsZ-binding region; KEGG: son:SO2897 cell division protein ZipA YP_001094504.1 TIGRFAM: chromosome segregation protein SMC; PFAM: SMC domain protein; KEGG: son:SO2898 SMC family protein YP_001094505.1 putative role in sulfur assimilation YP_001094506.1 PFAM: RDD domain containing protein; KEGG: she:Shewmr4_1501 RDD domain containing protein YP_001094507.1 TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: she:Shewmr4_1500 cysteine synthase A YP_001094508.1 PFAM: regulatory protein, TetR; KEGG: psp:PSPPH_3872 transcriptional regulator, TetR family YP_001094509.1 PFAM: O-methyltransferase, family 2; KEGG: sfr:Sfri_2128 O-methyltransferase, putative YP_001094510.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_2119 TonB-dependent receptor YP_001094511.1 PFAM: C4-dicarboxylate anaerobic carrier; KEGG: shm:Shewmr7_1563 C4-dicarboxylate anaerobic carrier YP_001094512.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_2469 transcriptional regulator, LysR family protein YP_001094513.1 PFAM: formate/nitrite transporter; CBS domain containing protein; KEGG: sfr:Sfri_2470 formate/nitrite transporter YP_001094514.1 KEGG: sfr:Sfri_2472 hypothetical protein YP_001094515.1 KEGG: shm:Shewmr7_1561 formate acetyltransferase; TIGRFAM: formate acetyltransferase; PFAM: formate C-acetyltransferase glycine radical; pyruvate formate-lyase, PFL YP_001094516.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_001094517.1 PFAM: protein of unknown function DUF412; KEGG: shm:Shewmr7_1559 protein of unknown function DUF412 YP_001094518.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_001094519.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_001094520.1 KEGG: son:SO2917 hypothetical protein YP_001094521.1 KEGG: shm:Shewmr7_1552 hypothetical protein YP_001094522.1 KEGG: sfr:Sfri_2556 hypothetical protein YP_001094523.1 PFAM: protein of unknown function UPF0118; KEGG: shm:Shewmr7_1550 protein of unknown function UPF0118 YP_001094524.1 catalyzes the formation of dihydromonapterin triphosphate from dihydroneopterin triphosphate YP_001094525.1 PFAM: NAD-dependent epimerase/dehydratase; Male sterility C-terminal domain; domain of unknown function DUF1731; KEGG: she:Shewmr4_1483 hypothetical protein YP_001094526.1 PFAM: protein of unknown function DUF214; KEGG: shm:Shewmr7_1545 protein of unknown function DUF214 YP_001094527.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sdn:Sden_2367 ABC transporter-related protein YP_001094528.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: she:Shewmr4_1478 arylesterase YP_001094529.1 KEGG: shm:Shewmr7_1539 hypothetical protein YP_001094530.1 KEGG: son:SO2931 hypothetical protein YP_001094531.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: she:Shewmr4_1471 transcriptional regulator, AraC family YP_001094532.1 SohB; periplasmic protein; member of the peptidase S49 family YP_001094533.1 KEGG: she:Shewmr4_1469 hypothetical protein YP_001094534.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1534 short-chain dehydrogenase/reductase SDR YP_001094535.1 PFAM: beta-ketoacyl synthase; KEGG: sfr:Sfri_1391 beta-ketoacyl synthase YP_001094536.1 PFAM: FAD dependent oxidoreductase; KEGG: sfr:Sfri_1390 FAD dependent oxidoreductase YP_001094537.1 PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: sdn:Sden_1541 tRNA/rRNA methyltransferase (SpoU) YP_001094538.1 KEGG: sdn:Sden_1540 hypothetical protein YP_001094539.1 PFAM: ATP-NAD/AcoX kinase; KEGG: son:SO3077 hypothetical protein YP_001094540.1 PFAM: nucleoside:H+ symporter; major facilitator superfamily MFS_1; KEGG: son:SO3078 major facilitator family protein, putative YP_001094541.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_001094542.1 involved in methylation of ribosomal protein L3 YP_001094543.1 PFAM: Smr protein/MutS2; KEGG: shm:Shewmr7_1479 Smr protein/MutS2 YP_001094544.1 TIGRFAM: phosphohistidine phosphatase SixA; PFAM: Phosphoglycerate mutase; KEGG: she:Shewmr4_1413 phosphohistidine phosphatase, SixA YP_001094545.1 PFAM: peptidase M16 domain protein; KEGG: son:SO3083 peptidase, M16 family YP_001094546.1 KEGG: shm:Shewmr7_1476 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001094547.1 KEGG: she:Shewmr4_1410 hypothetical protein YP_001094548.1 KEGG: sfr:Sfri_4067 hypothetical protein YP_001094549.1 KEGG: sdn:Sden_1531 hypothetical protein YP_001094550.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_001094551.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_001094552.1 PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: shm:Shewmr7_1471 ATPase associated with various cellular activities, AAA_3 YP_001094553.1 PFAM: protein of unknown function DUF58; KEGG: she:Shewmr4_1405 protein of unknown function DUF58 YP_001094554.1 KEGG: son:SO3092 hypothetical protein YP_001094555.1 PFAM: von Willebrand factor, type A; KEGG: shm:Shewmr7_1468 von Willebrand factor, type A YP_001094556.1 PFAM: TPR repeat-containing protein; von Willebrand factor, type A; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: shm:Shewmr7_1467 tetratricopeptide TPR_2 repeat protein YP_001094557.1 KEGG: shm:Shewmr7_1466 hypothetical protein YP_001094558.1 Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription YP_001094559.1 KEGG: shm:Shewmr7_1464 hypothetical protein YP_001094560.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: she:Shewmr4_1398 sodium/proline symporter YP_001094561.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: shm:Shewmr7_1462 membrane protein involved in aromatic hydrocarbon degradation YP_001094562.1 KEGG: shm:Shewmr7_1461 hypothetical protein YP_001094563.1 PFAM: protein of unknown function DUF541; KEGG: son:SO3101 hypothetical protein YP_001094564.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: she:Shewmr4_1394 efflux transporter, RND family, MFP subunit YP_001094565.1 PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_1458 acriflavin resistance protein YP_001094566.1 KEGG: shm:Shewmr7_1457 hypothetical protein YP_001094567.1 PFAM: Rhodanese domain protein; KEGG: son:SO3105 phage shock protein E YP_001094568.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; Proprotein convertase, P; protease-associated PA domain protein; peptidase domain protein; proteinase inhibitor I9, subtilisin propeptide; KEGG: sfr:Sfri_2692 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001094569.1 KEGG: shm:Shewmr7_2504 hypothetical protein YP_001094570.1 KEGG: sdn:Sden_0862 hypothetical protein YP_001094571.1 catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate YP_001094572.1 KEGG: shm:Shewmr7_2509 hypothetical protein YP_001094573.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_001094574.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_001094575.1 KEGG: shm:Shewmr7_2512 hypothetical protein YP_001094576.1 PFAM: Patatin; KEGG: sfr:Sfri_2444 patatin YP_001094577.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: son:SO2838 ATP-dependent RNA helicase, DEAD box family YP_001094578.1 KEGG: sdn:Sden_1416 hypothetical protein YP_001094579.1 PFAM: protein of unknown function DUF45; KEGG: son:SO2840 hypothetical protein YP_001094580.1 PFAM: peptidase M23B; Opacity-associated protein A; Opacity-associated protein A, N-terminal domain protein; KEGG: shm:Shewmr7_2518 peptidase M23B YP_001094581.1 PFAM: SMC domain protein; KEGG: son:SO2843 exonuclease SbcC, putative YP_001094582.1 TIGRFAM: nuclease SbcCD, D subunit; PFAM: metallophosphoesterase; KEGG: shm:Shewmr7_2520 nuclease SbcCD, D subunit YP_001094583.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: vpa:VPA1298 putative glutathione S-transferase YP_001094584.1 KEGG: vpa:VPA0120 hypothetical protein YP_001094585.1 KEGG: chu:CHU_1911 conserved hypothetical protein with multiple MORN variant repeat domains YP_001094586.1 PFAM: MORN variant repeat protein; KEGG: shm:Shewmr7_3193 hypothetical protein YP_001094587.1 KEGG: she:Shewmr4_0831 MORN variant repeat protein YP_001094588.1 KEGG: she:Shewmr4_0832 hypothetical protein YP_001094589.1 PFAM: protein of unknown function DUF81; KEGG: son:SO2846 hypothetical protein YP_001094590.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_2452 transcriptional regulator, LysR family YP_001094591.1 KEGG: son:SO0497 hypothetical protein YP_001094592.1 PFAM: protein of unknown function DUF1260; KEGG: shm:Shewmr7_2523 protein of unknown function DUF1260 YP_001094593.1 KEGG: shm:Shewmr7_2524 RNA-binding S4 domain protein YP_001094594.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_2455 GCN5-related N-acetyltransferase YP_001094595.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: shm:Shewmr7_2526 PpiC-type peptidyl-prolyl cis-trans isomerase YP_001094596.1 PFAM: protein of unknown function DUF885; KEGG: sfr:Sfri_2620 protein of unknown function DUF885 YP_001094597.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2528 diguanylate cyclase YP_001094598.1 KEGG: sfr:Sfri_2621 tetratricopeptide domain protein YP_001094599.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; KEGG: sdn:Sden_2421 TonB-like protein YP_001094600.1 PFAM: Biopolymer transport protein ExbD/TolR; KEGG: sdn:Sden_2422 biopolymer transport protein ExbD/TolR YP_001094601.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: she:Shewmr4_2462 MotA/TolQ/ExbB proton channel YP_001094602.1 PFAM: MotA/TolQ/ExbB proton channel; KEGG: shm:Shewmr7_2533 MotA/TolQ/ExbB proton channel YP_001094603.1 KEGG: sdn:Sden_2425 hypothetical protein YP_001094604.1 PFAM: Methyltransferase type 11; KEGG: sfr:Sfri_2627 methyltransferase type 11 YP_001094605.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_2628 TonB-dependent receptor YP_001094606.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_2468 porin, gram-negative type YP_001094607.1 Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C YP_001094608.1 helicase involved in DNA repair and perhaps also replication YP_001094609.1 PFAM: protein of unknown function DUF81; KEGG: shm:Shewmr7_2539 protein of unknown function DUF81 YP_001094610.1 KEGG: son:SO1817 primosomal replication protein N'', putative YP_001094611.1 KEGG: she:Shewmr4_2473 hypothetical protein YP_001094612.1 PFAM: histone deacetylase superfamily; KEGG: she:Shewmr4_2474 histone deacetylase superfamily YP_001094613.1 KEGG: son:SO1814 hypothetical protein YP_001094614.1 KEGG: she:Shewmr4_2476 competence protein ComEA helix-hairpin-helix repeat protein; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat protein; PFAM: helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding, class 1 YP_001094615.1 TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; TRAP C4-dicarboxylate transport system permease DctM subunit; KEGG: shm:Shewmr7_3574 anion transporter YP_001094616.1 PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO1812 methionine gamma-lyase YP_001094617.1 PFAM: conserved hypothetical protein 1620; KEGG: son:SO1811 hypothetical protein YP_001094618.1 PFAM: protein of unknown function DUF463, YcjX family protein; KEGG: sfr:Sfri_2575 protein of unknown function DUF463, YcjX family protein YP_001094619.1 PFAM: PspC domain protein; KEGG: sfr:Sfri_2576 phage shock protein C, PspC YP_001094620.1 acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding YP_001094621.1 PFAM: PspA/IM30 family protein; KEGG: shm:Shewmr7_2550 phage shock protein A, PspA YP_001094622.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_2551 transcriptional regulator, fis family YP_001094623.1 PFAM: extracellular solute-binding protein, family 5; KEGG: she:Shewmr4_2484 extracellular solute-binding protein, family 5 YP_001094624.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2553 binding-protein-dependent transport systems inner membrane component YP_001094625.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_2554 binding-protein-dependent transport systems inner membrane component YP_001094626.1 TIGRFAM: oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-related protein; Oligopeptide/dipeptide ABC transporter, C-terminal domain protein; KEGG: she:Shewmr4_2487 oligopeptide/dipeptide ABC transporter, ATPase subunit YP_001094627.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2488 ABC transporter-related protein YP_001094628.1 enzyme from Treponema denticola exhibits NADH-dependent trans-2-enoyl-CoA reductase activity YP_001094629.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: son:SO1798 peptidyl-prolyl cis-trans isomerase D YP_001094630.1 PFAM: histone family protein DNA-binding protein; KEGG: sfr:Sfri_2593 histone family protein DNA-binding protein YP_001094631.1 KEGG: shm:Shewmr7_2561 ATP-dependent protease La; TIGRFAM: ATP-dependent protease La; PFAM: peptidase S16, lon domain protein; AAA ATPase, central domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001094632.1 binds and unfolds substrates as part of the ClpXP protease YP_001094633.1 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates YP_001094634.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_001094635.1 catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate YP_001094636.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_001094637.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: son:SO1790 peptidyl-prolyl cis-trans isomerase B YP_001094638.1 catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine YP_001094639.1 PFAM: tRNA--hydroxylase; KEGG: shm:Shewmr7_2569 tRNA hydroxylase YP_001094640.1 PFAM: protein of unknown function DUF1282; KEGG: she:Shewmr4_2502 protein of unknown function DUF1282 YP_001094641.1 catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA YP_001094642.1 TIGRFAM: ferrous iron transport protein B; small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Ferrous iron transport protein B domain protein; Ferrous iron transport B domain protein; nucleoside recognition domain protein; Miro domain protein; KEGG: son:SO1784 ferrous iron transport protein B YP_001094643.1 PFAM: FeoA family protein; KEGG: son:SO1783 ferrous iron transport protein A YP_001094644.1 TIGRFAM: cytochrome C family protein; KEGG: shm:Shewmr7_2574 cytochrome c family protein YP_001094645.1 KEGG: she:Shewmr4_2507 outer membrane protein, putative YP_001094646.1 KEGG: shm:Shewmr7_2576 decaheme cytochrome c MtrF YP_001094647.1 KEGG: shm:Shewmr7_2577 decaheme cytochrome c YP_001094648.1 KEGG: shm:Shewmr7_2577 decaheme cytochrome c YP_001094649.1 KEGG: shm:Shewmr7_2577 decaheme cytochrome c YP_001094650.1 KEGG: son:SO1778 decaheme cytochrome c YP_001094651.1 TIGRFAM: cytochrome C family protein; KEGG: shm:Shewmr7_2579 cytochrome c family protein YP_001094652.1 KEGG: shm:Shewmr7_2580 outer membrane protein precursor MtrB YP_001094653.1 PFAM: sugar diacid recognition domain protein; KEGG: she:Shewmr4_2516 transcriptional regulator, CdaR YP_001094654.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_0886 pseudouridine synthase YP_001094655.1 PFAM: C4-dicarboxylate transporter/malic acid transport protein; KEGG: vpa:VP2377 hypothetical protein YP_001094656.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VP2378 transcriptional regulator, LysR family YP_001094657.1 PFAM: glutamine amidotransferase class-I; peptidase C26; KEGG: pen:PSEEN2659 glutamine amidopeptidase (class I) YP_001094658.1 PFAM: Gluconate transporter; Citrate transporter; KEGG: shm:Shewmr7_2586 gluconate transporter YP_001094659.1 PFAM: glycerate kinase; KEGG: she:Shewmr4_2519 glycerate kinase YP_001094660.1 PFAM: Pyridoxal-dependent decarboxylase; KEGG: she:Shewmr4_2520 pyridoxal-dependent decarboxylase YP_001094661.1 PFAM: putative thiol-disulphide oxidoreductase DCC; KEGG: pha:PSHAa1311 hypothetical protein YP_001094662.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: son:SO1762 transcriptional regulator, AraC/XylS family YP_001094663.1 PFAM: AzlC family protein; KEGG: she:Shewmr4_2528 AzlC family protein YP_001094664.1 PFAM: branched-chain amino acid transport; KEGG: she:Shewmr4_2529 branched-chain amino acid transport YP_001094665.1 PFAM: NIPSNAP family containing protein; KEGG: bur:Bcep18194_B0447 protein of unknown function DUF1099 YP_001094666.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: shm:Shewmr7_2605 helix-turn-helix, type 11 domain protein YP_001094667.1 PFAM: transcription activator, effector binding; KEGG: she:Shewmr4_2539 transcription activator, effector binding YP_001094668.1 KEGG: cps:CPS_3399 glyoxalase family protein YP_001094669.1 PFAM: phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: shm:Shewmr7_2608 phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I YP_001094670.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: she:Shewmr4_3320 diguanylate cyclase YP_001094671.1 KEGG: sfr:Sfri_1423 hypothetical protein YP_001094672.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_0787 pseudouridine synthase YP_001094673.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: vfi:VFA0260 glutathione-regulated potassium-efflux system protein KefC YP_001094674.1 PFAM: NAD(P)H dehydrogenase (quinone); KEGG: vvy:VV2527 putative NADPH-quinone reductase YP_001094675.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sdn:Sden_0926 GCN5-related N-acetyltransferase YP_001094676.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_001094677.1 KEGG: son:SO1675 hypothetical protein YP_001094678.1 PFAM: short-chain dehydrogenase/reductase SDR; KEGG: shm:Shewmr7_2667 short-chain dehydrogenase/reductase SDR YP_001094679.1 receptor for colicin S4 YP_001094680.1 KEGG: shm:Shewmr7_1695 hypothetical protein YP_001094681.1 KEGG: shm:Shewmr7_1694 acyl-CoA thioesterase II; TIGRFAM: acyl-CoA thioesterase II; PFAM: acyl-CoA thioesterase YP_001094682.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_1693 short-chain dehydrogenase/reductase SDR YP_001094683.1 TIGRFAM: 1,4-dihydroxy-2-naphthoate octaprenyltransferase; PFAM: UbiA prenyltransferase; KEGG: son:SO1910 1,4-dihydroxy-2-naphthoate octaprenyltransferase YP_001094684.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_001094685.1 PFAM: helix-turn-helix domain protein; KEGG: she:Shewmr4_3851 transcriptional regulator, XRE family YP_001094686.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_001094687.1 PFAM: regulatory protein, MarR; KEGG: ppr:PBPRB1157 putative transcriptional regulator, MarR family YP_001094688.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; KEGG: ppr:PBPRB1158 hypothetical alcohol dehydrogenase, zinc-containing YP_001094689.1 PFAM: MltA-interacting MipA family protein; KEGG: vpa:VPA0318 putative outer membrane protein OmpV YP_001094690.1 KEGG: sfr:Sfri_3620 hypothetical protein YP_001094691.1 KEGG: son:SO4656 hypothetical protein YP_001094692.1 PFAM: MORN variant repeat protein; KEGG: fnu:FN2119 hypothetical exported 24-amino acid repeat protein YP_001094693.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_2391 AMP-dependent synthetase and ligase YP_001094694.1 PFAM: regulatory protein, MerR; KEGG: sdn:Sden_2244 regulatory protein, MerR YP_001094695.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: shm:Shewmr7_2394 acyl-CoA dehydrogenase domain protein YP_001094696.1 PFAM: carboxyl transferase; KEGG: sdn:Sden_2246 propionyl-CoA carboxylase YP_001094697.1 PFAM: Enoyl-CoA hydratase/isomerase; KEGG: shm:Shewmr7_2396 enoyl-CoA hydratase/isomerase YP_001094698.1 PFAM: biotin/lipoyl attachment domain-containing protein; phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: shm:Shewmr7_2397 carbamoyl-phosphate synthase L chain, ATP-binding protein YP_001094699.1 PFAM: pyruvate carboxyltransferase; KEGG: sfr:Sfri_2731 pyruvate carboxyltransferase YP_001094700.1 KEGG: shm:Shewmr7_2399 3-oxoacid CoA-transferase, A subunit; TIGRFAM: 3-oxoacid CoA-transferase, A subunit; PFAM: coenzyme A transferase YP_001094701.1 KEGG: sdn:Sden_2252 3-oxoacid CoA-transferase, subunit B; TIGRFAM: 3-oxoacid CoA-transferase, B subunit; PFAM: coenzyme A transferase YP_001094702.1 KEGG: shm:Shewmr7_1220 methyl-accepting chemotaxis sensory transducer with PAS/Pac sensor; TIGRFAM: PAS sensor protein; PFAM: chemotaxis sensory transducer; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAC repeat-containing protein YP_001094703.1 PFAM: extracellular solute-binding protein, family 3; KEGG: ctc:CTC02323 sensory transduction protein kinase YP_001094704.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_001094705.1 KEGG: shm:Shewmr7_1421 hypothetical protein YP_001094706.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: she:Shewmr4_1355 peptidyl-dipeptidase DCP YP_001094707.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_1419 Na+/H+ antiporter NhaC YP_001094708.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: shm:Shewmr7_1418 electron transfer flavoprotein, alpha subunit YP_001094709.1 PFAM: electron transfer flavoprotein beta-subunit; KEGG: sfr:Sfri_2748 electron transfer flavoprotein beta-subunit YP_001094710.1 PFAM: histone family protein nucleoid-structuring protein H-NS; KEGG: shm:Shewmr7_1416 histone family protein nucleoid-structuring protein H-NS YP_001094711.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: she:Shewmr4_1350 amidohydrolase YP_001094712.1 KEGG: son:SO3149 hypothetical protein YP_001094713.1 KEGG: shm:Shewmr7_1413 lipoprotein, putative YP_001094714.1 PFAM: protein of unknown function UPF0066; KEGG: she:Shewmr4_1347 protein of unknown function UPF0066 YP_001094715.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: sfr:Sfri_2752 transferase hexapeptide repeat-containing protein YP_001094717.1 PFAM: peptidase M28; KEGG: sfr:Sfri_1287 peptidase M28 YP_001094718.1 activates fatty acids by binding to coenzyme A YP_001094720.1 KEGG: cps:CPS_0198 hypothetical protein YP_001094721.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_001094723.1 KEGG: rpd:RPD_3143 hypothetical protein YP_001094724.1 PFAM: helix-turn-helix, HxlR type; KEGG: vch:VCA0094 hypothetical protein YP_001094725.1 KEGG: son:SO2061 hypothetical protein YP_001094726.1 KEGG: shm:Shewmr7_0997 hypothetical protein YP_001094728.1 KEGG: pol:Bpro_4802 hypothetical protein YP_001094729.1 PFAM: restriction endonuclease; KEGG: sfr:Sfri_2536 hypothetical protein YP_001094730.1 KEGG: cps:CPS_3411 putative phenylacetate-coenzyme A ligase YP_001094731.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sfr:Sfri_1836 ABC transporter-related protein YP_001094732.1 KEGG: sfr:Sfri_1835 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding protein YP_001094733.1 PFAM: inner-membrane translocator; KEGG: cps:CPS_3414 putative branched-chain amino acid ABC transporter, permease protein YP_001094734.1 PFAM: inner-membrane translocator; KEGG: cps:CPS_3415 putative branched-chain amino acid ABC transporter, permease protein YP_001094735.1 PFAM: AMP-dependent synthetase and ligase; KEGG: cps:CPS_3416 putative branched-chain amino acid ABC transporter, periplasmic branched-chain amino acid-binding YP_001094736.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: cps:CPS_3417 putative branched-chain amino acid ABC transporter, ATP-binding protein YP_001094737.1 KEGG: cps:CPS_3418 hypothetical protein YP_001094738.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: sfr:Sfri_1829 periplasmic sensor hybrid histidine kinase YP_001094739.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: cps:CPS_3420 DNA-binding response regulator, LuxR family YP_001094740.1 PFAM: Patatin; KEGG: shm:Shewmr7_1409 patatin YP_001094741.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: bpm:BURPS1710b_0124 GDSL-like lipase/acylhydrolase domain protein YP_001094742.1 TIGRFAM: potassium efflux system protein; PFAM: TrkA-N domain protein; TrkA-C domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_2690 potassium efflux system protein YP_001094743.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2691 diguanylate cyclase YP_001094744.1 TIGRFAM: tRNA(Ile)-lysidine synthetase; PFAM: PP-loop domain protein; KEGG: shm:Shewmr7_2692 tRNA(Ile)-lysidine synthetase YP_001094745.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_001094746.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_001094747.1 catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM YP_001094748.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_001094749.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_001094750.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_001094751.1 PFAM: outer membrane chaperone Skp (OmpH); KEGG: shm:Shewmr7_2699 outer membrane chaperone Skp (OmpH) YP_001094752.1 PFAM: surface antigen (D15); surface antigen variable number repeat protein; KEGG: shm:Shewmr7_2700 surface antigen (D15) YP_001094753.1 KEGG: son:SO1636 membrane-associated zinc metalloprotease, putative; TIGRFAM: putative membrane-associated zinc metalloprotease; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein YP_001094754.1 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_001094755.1 PFAM: phosphatidate cytidylyltransferase; KEGG: shm:Shewmr7_2703 phosphatidate cytidylyltransferase YP_001094756.1 KEGG: shm:Shewmr7_2704 undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase; PFAM: Di-trans-poly-cis-decaprenylcistransferase YP_001094757.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_001094758.1 Catalyzes the phosphorylation of UMP to UDP YP_001094759.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_001094760.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_001094761.1 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn YP_001094762.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_001094763.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_001094764.1 KEGG: she:Shewmr4_2645 hypothetical protein YP_001094765.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_001094766.1 TIGRFAM: PTS system, glucose-like IIB subunint; PFAM: phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: sfr:Sfri_1264 PTS system, glucose-like IIB subunint YP_001094767.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001094768.1 PFAM: pseudouridine synthase; KEGG: sfr:Sfri_1262 pseudouridylate synthase YP_001094769.1 PFAM: protein of unknown function DUF446; KEGG: son:SO1619 hypothetical protein YP_001094770.1 KEGG: she:Shewmr4_2652 hypothetical protein YP_001094771.1 KEGG: son:SO1617 hypothetical protein YP_001094772.1 KEGG: son:SO1615 hypothetical protein YP_001094773.1 PFAM: GCN5-related N-acetyltransferase; KEGG: son:SO1614 acetyltransferase, GNAT family YP_001094774.1 KEGG: son:SO1613 hypothetical protein YP_001094775.1 KEGG: son:SO1612 hypothetical protein YP_001094776.1 KEGG: sfr:Sfri_1252 hypothetical protein YP_001094777.1 KEGG: shm:Shewmr7_2726 hypothetical protein YP_001094778.1 putative SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_001094779.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_001094780.1 KEGG: sde:Sde_2267 hypothetical protein YP_001094781.1 PFAM: 4'-phosphopantetheinyl transferase; KEGG: son:SO1604 4'-phosphopantetheinyl transferase family protein YP_001094782.1 KEGG: ppr:PBPRB1123 hypothetical protein YP_001094783.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: ppr:PBPRB1124 putative ABC transporter, ATP-binding protein YP_001094784.1 PFAM: protein of unknown function DUF214; KEGG: ppr:PBPRB1125 hypothetical protein YP_001094785.1 PFAM: protein of unknown function DUF214; KEGG: ppr:PBPRB1126 hypothetical protein YP_001094786.1 KEGG: vpa:VPA0557 hypothetical protein YP_001094787.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: sdn:Sden_3023 cupin 2, conserved barrel YP_001094788.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_001094789.1 KEGG: shm:Shewmr7_2732 transcriptional regulator, putative YP_001094790.1 PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; KR; KEGG: ppr:PBPRA1460 omega-3 polyunsaturated fatty acid synthase PfaA YP_001094791.1 KEGG: ppr:PBPRA1459 omega-3 polyunsaturated fatty acid synthase PfaB YP_001094792.1 PFAM: beta-ketoacyl synthase; Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: ppr:PBPRA1458 omega-3 polyunsaturated fatty acid synthase PfaC YP_001094793.1 PFAM: 2-nitropropane dioxygenase, NPD; KEGG: sfr:Sfri_1218 2-nitropropane dioxygenase, NPD YP_001094794.1 PFAM: peptidase S45, penicillin amidase; KEGG: pha:PSHAa0079 hydrolase YP_001094795.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_0384 transcriptional regulator, LysR family protein YP_001094796.1 PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: sth:STH2125 putative lipase YP_001094797.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_001094798.1 PFAM: AMP-dependent synthetase and ligase; KEGG: stm:STM0071 crotonobetaine/carnitine-CoA ligase YP_001094799.1 catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine YP_001094800.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_001094801.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_001094802.1 required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase YP_001094803.1 PFAM: electron transfer flavoprotein beta-subunit; electron transfer flavoprotein, alpha subunit; KEGG: stm:STM0076 putative electron transfer flavoprotein, carnitine metabolism YP_001094804.1 PFAM: monooxygenase, FAD-binding; fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: stt:t0078 FixC protein YP_001094805.1 KEGG: stm:STM1351 putative ferredoxin YP_001094806.1 PFAM: General substrate transporter; major facilitator superfamily MFS_1; KEGG: stm:STM0079 putative transport protein YP_001094807.1 KEGG: son:SO1412 hypothetical protein YP_001094808.1 KEGG: sfr:Sfri_3228 hypothetical protein YP_001094809.1 KEGG: she:Shewmr4_3453 hypothetical protein YP_001094810.1 KEGG: cps:CPS_2706 putative lipoprotein YP_001094811.1 KEGG: cps:CPS_2706 putative lipoprotein YP_001094812.1 TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein; KEGG: she:Shewmr4_0667 molybdenum ABC transporter, periplasmic molybdate-binding protein YP_001094813.1 KEGG: sfr:Sfri_3605 amidohydrolase; TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001094814.1 PFAM: sulfotransferase; KEGG: sfr:Sfri_0789 sulfotransferase YP_001094815.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_1347 TonB-dependent receptor YP_001094816.1 KEGG: shm:Shewmr7_3765 OmpA domain protein transmembrane region-containing protein YP_001094817.1 PFAM: cytochrome B561; KEGG: shm:Shewmr7_2387 cytochrome b561 YP_001094818.1 KEGG: shm:Shewmr7_3906 hypothetical protein YP_001094819.1 PFAM: Propeptide, PepSY amd peptidase M4; KEGG: sfr:Sfri_1133 propeptide, PepSY amd peptidase M4 YP_001094820.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: she:Shewmr4_3817 two component transcriptional regulator, winged helix family YP_001094821.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: sdn:Sden_1263 ATP-binding region, ATPase-like protein YP_001094822.1 KEGG: she:Shewmr4_3819 hypothetical protein YP_001094823.1 KEGG: she:Shewmr4_2687 hypothetical protein YP_001094824.1 PFAM: cyclic nucleotide-binding; KEGG: shm:Shewmr7_2756 cyclic nucleotide-binding protein YP_001094825.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: ppr:PBPRB1064 hypothetical protein YP_001094826.1 KEGG: mac:MA3214 hypothetical protein YP_001094828.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: lpf:lpl1180 hypothetical protein YP_001094829.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001094830.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001094831.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001094832.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001094833.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001094834.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001094835.1 KEGG: sdn:Sden_0823 O-acetylhomoserine/O-acetylserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes YP_001094836.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; Cupin 2, conserved barrel domain protein; KEGG: rru:Rru_A0140 transcriptional regulator, AraC family YP_001094837.1 PFAM: peptidase S15; KEGG: pae:PA3829 hypothetical protein YP_001094838.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: hch:HCH_00654 response regulator containing a CheY-like receiver domain and an HD-GYP domain YP_001094839.1 KEGG: sfr:Sfri_3123 hypothetical protein YP_001094840.1 PFAM: protein of unknown function DUF599; KEGG: son:SO3776 hypothetical protein YP_001094841.1 PFAM: peptidase S41; KEGG: sfr:Sfri_0592 peptidase S41 YP_001094842.1 KEGG: sfr:Sfri_0593 hypothetical protein YP_001094843.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_0415 TonB-dependent receptor YP_001094844.1 KEGG: vch:VC1858 hypothetical protein YP_001094845.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: sdn:Sden_3290 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001094846.1 KEGG: son:SO1588 hypothetical protein YP_001094847.1 KEGG: sdn:Sden_2403 hypothetical protein YP_001094848.1 PFAM: NUDIX hydrolase; KEGG: ppr:PBPRB0617 putative MutT/NUDIX family protein YP_001094849.1 PFAM: Indigoidine synthase A family protein; KEGG: hch:HCH_01392 uncharacterized enzyme involved in pigment biosynthesis YP_001094850.1 PFAM: PfkB domain protein; Helix-turn-helix, type 11 domain protein; KEGG: hch:HCH_01393 sugar kinase, ribokinase family YP_001094851.1 PFAM: protein of unknown function DUF188; KEGG: cps:CPS_3584 hypothetical protein YP_001094852.1 KEGG: shm:Shewmr7_2761 hypothetical protein YP_001094853.1 KEGG: lic:LIC10692 hypothetical protein YP_001094854.1 PFAM: regulatory protein, TetR; KEGG: shm:Shewmr7_2762 transcriptional regulator, TetR family YP_001094855.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: son:SO1577 glutathione S-transferase family protein YP_001094857.1 KEGG: mag:amb3154 hypothetical protein YP_001094858.1 PFAM: GCN5-related N-acetyltransferase; KEGG: chy:CHY_0724 ribosomal-protein-alanine acetyltransferase YP_001094859.1 TIGRFAM: 4-carboxymuconolactone decarboxylase; PFAM: Carboxymuconolactone decarboxylase; KEGG: shm:Shewmr7_0571 carboxymuconolactone decarboxylase YP_001094860.1 PFAM: Patatin; KEGG: she:Shewmr4_3733 patatin YP_001094861.1 PFAM: regulatory protein, MarR; KEGG: shm:Shewmr7_2839 transcriptional regulator, MarR family YP_001094862.1 PFAM: helix-turn-helix- domain containing protein, AraC type; KEGG: cps:CPS_4694 transcriptional regulator, AraC family YP_001094863.1 TIGRFAM: alkylhydroperoxidase like protein, AhpD family; PFAM: Carboxymuconolactone decarboxylase; KEGG: pat:Patl_2623 alkylhydroperoxidase like protein, AhpD family YP_001094864.1 PFAM: Fmu (Sun) domain protein; KEGG: son:SO1575 NOL1/NOP2/sun family putative RNA methylase YP_001094865.1 PFAM: YfaZ family protein; KEGG: shm:Shewmr7_2770 YfaZ family protein YP_001094866.1 PFAM: glutathione peroxidase; KEGG: sdn:Sden_2552 glutathione peroxidase YP_001094867.1 PFAM: peptidase M1, membrane alanine aminopeptidase; KEGG: she:Shewmr4_2706 peptidase M1, membrane alanine aminopeptidase YP_001094868.1 PFAM: Peptidase M9A, collagenase C-terminal domain protein; KEGG: cps:CPS_1458 microbial collagenase YP_001094869.1 PFAM: putative esterase; KEGG: pat:Patl_3925 putative esterase YP_001094870.1 KEGG: csa:Csal_2788 hypothetical protein YP_001094871.1 KEGG: rsp:RSP_3545 hypothetical protein YP_001094872.1 TIGRFAM: phosphate binding protein; KEGG: sfr:Sfri_2766 phosphate binding protein YP_001094873.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; PAS fold domain protein; SMART: PAS domain containing protein; KEGG: son:SO1559 phosphate regulon sensor protein PhoR YP_001094874.1 TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: son:SO1558 phosphate regulon response regulator PhoB YP_001094875.1 PFAM: porin, Gram-negative type; KEGG: shm:Shewmr7_2778 porin, gram-negative type YP_001094876.1 Required for efficient pilin antigenic variation YP_001094877.1 PFAM: peptidase M61 domain protein; SMART: PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_2712 peptidase M61 domain protein YP_001094878.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: she:Shewmr4_2713 TPR repeat-containing protein YP_001094879.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: shm:Shewmr7_2782 diguanylate cyclase YP_001094880.1 PFAM: conserved hypothetical protein 730; KEGG: shm:Shewmr7_2783 conserved hypothetical protein 730 YP_001094881.1 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_001094882.1 KEGG: shm:Shewmr7_2785 hypothetical protein YP_001094883.1 KEGG: gvi:gll2461 hypothetical protein YP_001094884.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; KEGG: shm:Shewmr7_2790 peptidase S9, prolyl oligopeptidase active site domain protein YP_001094885.1 catalyzes the formation of 2-oxoglutarate from isocitrate YP_001094886.1 KEGG: son:SO1536 hypothetical protein YP_001094887.1 PFAM: protein of unknown function DUF423; KEGG: son:SO1535 hypothetical protein YP_001094888.1 PFAM: dienelactone hydrolase; KEGG: shm:Shewmr7_2794 hypothetical protein YP_001094889.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_001094890.1 KEGG: sfr:Sfri_2784 hypothetical protein YP_001094891.1 Required for the synthesis of the thiazole moiety YP_001094892.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine; Vibrio parahaemolyticus protein is associated with the polar flagella YP_001094893.1 Homologous to MotA in E. coli and Salmonella. With PomB forms the ion channels that couple flagellar rotation to sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine. YP_001094894.1 TIGRFAM: exodeoxyribonuclease VII, small subunit; PFAM: Exonuclease VII, small subunit; KEGG: shm:Shewmr7_2802 exodeoxyribonuclease VII, small subunit YP_001094895.1 PFAM: Polyprenyl synthetase; KEGG: son:SO1526 geranyltranstransferase YP_001094896.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_001094897.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_001094898.1 catalyzes the phosphorylation of NAD to NADP YP_001094899.1 TIGRFAM: TonB family protein; KEGG: son:SO4043 TonB domain protein YP_001094900.1 TIGRFAM: MATE efflux family protein; PFAM: multi antimicrobial extrusion protein MatE; KEGG: son:SO1506 MATE efflux family protein YP_001094901.1 PFAM: cobalamin synthesis protein, P47K; KEGG: shm:Shewmr7_2829 cobalamin synthesis protein, P47K YP_001094902.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_2752 DEAD/DEAH box helicase domain protein YP_001094903.1 KEGG: she:Shewmr4_2753 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; 5TM Receptors of the LytS-YhcK type, transmembrane region; PAS fold-3 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001094904.1 KEGG: sfr:Sfri_1026 conserved hypothetical amino acid ABC transporter YP_001094905.1 PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_1139 thioesterase superfamily protein YP_001094906.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: she:Shewmr4_1066 diguanylate cyclase/phosphodiesterase YP_001094907.1 PFAM: HDOD; KEGG: shm:Shewmr7_1137 putative signal transduction protein YP_001094908.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_1136 peptidase U32 YP_001094909.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: ppr:PBPRB1965 putative PAP2 family protein YP_001094910.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_1135 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001094911.1 PFAM: Sterol-binding domain protein; KEGG: shm:Shewmr7_1134 sterol-binding domain protein YP_001094912.1 PFAM: peptidase U32; KEGG: shm:Shewmr7_1133 peptidase U32 YP_001094913.1 PFAM: peptidase U32; KEGG: she:Shewmr4_1060 peptidase U32 YP_001094914.1 KEGG: she:Shewmr4_1059 hypothetical protein YP_001094915.1 PFAM: nucleoside recognition domain protein; KEGG: she:Shewmr4_1058 nucleoside recognition domain protein YP_001094916.1 PFAM: ATP-binding region, ATPase domain protein domain protein; Two component regulator propeller; Two component regulator three Y domain protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein; KEGG: son:SO0341 sensory box protein YP_001094917.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: son:SO1238 acyltransferase family protein YP_001094918.1 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica. YP_001094919.1 PFAM: CBS domain containing protein; KEGG: she:Shewmr4_1055 CBS domain containing protein YP_001094920.1 PFAM: Xanthine/uracil/vitamin C permease; sulphate transporter; KEGG: sfr:Sfri_3048 xanthine/uracil/vitamin C permease YP_001094921.1 PFAM: periplasmic nitrate reductase NapE; KEGG: sfr:Sfri_1996 periplasmic nitrate reductase NapE YP_001094922.1 TIGRFAM: trimethylamine-N-oxide reductase c-type cytochrome TorC; PFAM: NapC/NirT cytochrome c domain protein; KEGG: sfr:Sfri_1995 trimethylamine-N-oxide reductase C-type cytochrome TorC YP_001094923.1 TIGRFAM: trimethylamine-N-oxide reductase TorA; PFAM: molybdopterin oxidoreductase; molydopterin dinucleotide-binding region; KEGG: sfr:Sfri_1994 trimethylamine-N-oxide reductase TorA YP_001094924.1 TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor YP_001094925.1 PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: she:Shewmr4_1161 DEAD/DEAH box helicase domain protein YP_001094926.1 PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; KEGG: sfr:Sfri_1992 multi-sensor hybrid histidine kinase YP_001094927.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_001094928.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_001094929.1 PFAM: type IV pilus assembly PilZ; KEGG: she:Shewmr4_1046 type IV pilus assembly PilZ YP_001094930.1 PFAM: Choloylglycine hydrolase; KEGG: bba:Bd0665 choloylglycine hydrolase YP_001094931.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_2181 acetyltransferase, GNAT family YP_001094932.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_001094933.1 PFAM: type IV pilus assembly PilZ; KEGG: she:Shewmr4_1044 type IV pilus assembly PilZ YP_001094934.1 KEGG: shm:Shewmr7_1108 alpha/beta hydrolase fold YP_001094935.1 KEGG: she:Shewmr4_1042 phosphoserine phosphatase SerB; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase YP_001094936.1 KEGG: shm:Shewmr7_1106 membrane protein YP_001094937.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_001094938.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_001094939.1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate YP_001094940.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_001094941.1 PFAM: nucleoside-specific channel-forming protein, Tsx; KEGG: shm:Shewmr7_1101 nucleoside-specific channel-forming protein, Tsx YP_001094942.1 TIGRFAM: nucleoside transporter; PFAM: Na+ dependent nucleoside transporter; nucleoside recognition domain protein; Na+ dependent nucleoside transporter domain protein; KEGG: shm:Shewmr7_1100 nucleoside transporter YP_001094943.1 PFAM: TatD-related deoxyribonuclease; KEGG: son:SO1213 hydrolase, TatD family YP_001094944.1 KEGG: sfr:Sfri_0998 hypothetical protein YP_001094945.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_001094946.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_001094947.1 KEGG: son:SO1209 polyribonucleotide nucleotidyltransferase; PFAM: 3' exoribonuclease; RNA binding S1 domain protein; KH, type 1, domain protein; SMART: KH domain protein YP_001094948.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; KEGG: shm:Shewmr7_1095 diguanylate cyclase/phosphodiesterase YP_001094949.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_001094950.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_001094951.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_001094952.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_001094953.1 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination YP_001094954.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_001094955.1 TIGRFAM: preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; KEGG: son:SO1201 preprotein translocase, SecG subunit YP_001094956.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_001094957.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_001094958.1 KEGG: shm:Shewmr7_1085 dihydropteroate synthase; TIGRFAM: dihydropteroate synthase; PFAM: dihydropteroate synthase, DHPS YP_001094959.1 KEGG: son:SO1197 cell division protein FtsH; TIGRFAM: ATP-dependent metalloprotease FtsH; PFAM: peptidase M41; AAA ATPase, central domain protein; peptidase M41, FtsH extracellular; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001094960.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_001094961.1 PFAM: protein of unknown function UPF0044; KEGG: shm:Shewmr7_1082 protein of unknown function UPF0044 YP_001094962.1 TIGRFAM: transcription elongation factor GreA; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: sfr:Sfri_0977 transcription elongation factor GreA YP_001094963.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_001094964.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_001094965.1 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis YP_001094966.1 PFAM: FKBP-type peptidyl-prolyl isomerase domain protein; peptidylprolyl isomerase, FKBP-type; KEGG: shm:Shewmr7_1001 peptidylprolyl isomerase, FKBP-type YP_001094967.1 PFAM: peptidase M48, Ste24p; KEGG: shm:Shewmr7_1000 peptidase M48, Ste24p YP_001094968.1 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion YP_001094969.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_001094970.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: she:Shewmr4_0956 protein of unknown function DUF6, transmembrane YP_001094971.1 KEGG: ilo:IL0884 secreted protein containing internal repeats YP_001094972.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_001094973.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001094974.1 PFAM: Xanthine/uracil/vitamin C permease; KEGG: shm:Shewmr7_0989 xanthine/uracil/vitamin C permease YP_001094976.1 PFAM: peptidase M17, leucyl aminopeptidase domain protein; KEGG: she:Shewmr4_0949 peptidase M17, leucyl aminopeptidase domain protein YP_001094977.1 KEGG: shm:Shewmr7_0986 aminoacyl-histidine dipeptidase; TIGRFAM: aminoacyl-histidine dipeptidase; PFAM: peptidase M20; peptidase dimerisation domain protein YP_001094979.1 KEGG: vpa:VP1817 hypothetical protein YP_001094980.1 KEGG: mes:Meso_1882 hypothetical protein YP_001094981.1 PFAM: ThiJ/PfpI domain protein; KEGG: vvu:VV12405 putative intracellular protease/amidase YP_001094982.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bcn:Bcen_5015 transcriptional regulator, LysR family YP_001094983.1 KEGG: bur:Bcep18194_B3098 acetyl-CoA C-acyltransferase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase YP_001094984.1 PFAM: Phosphoglycerate mutase; KEGG: abo:ABO_0956 phosphoglycerate mutase, putative YP_001094985.1 PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: sfr:Sfri_2069 acyl-CoA dehydrogenase domain protein YP_001094986.1 PFAM: aminoglycoside phosphotransferase; KEGG: abo:ABO_0958 hypothetical protein YP_001094987.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: reu:Reut_C6406 short-chain dehydrogenase/reductase SDR YP_001094988.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: bur:Bcep18194_B3036 short-chain dehydrogenase/reductase SDR YP_001094989.1 PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding; KEGG: pat:Patl_1916 3-hydroxyacyl-CoA dehydrogenase, NAD-binding YP_001094990.1 PFAM: regulatory protein, TetR; KEGG: fal:FRAAL1231 putative TetR-family transcriptional regulator YP_001094991.1 activates fatty acids by binding to coenzyme A YP_001094992.1 PFAM: carboxyl transferase; biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: pae:PA1400 pyruvate carboxylase subunit A YP_001094993.1 PFAM: acyl-CoA dehydrogenase domain protein; KEGG: pen:PSEEN5004 probable acyl-CoA dehydrogenase YP_001094994.1 PFAM: peptidase S15; X-Pro dipeptidyl-peptidase C-terminal domain protein; KEGG: cps:CPS_3343 putative acylase YP_001094995.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_3344 TonB-dependent receptor YP_001094996.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_001094997.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: sdn:Sden_0991 bacterioferritin YP_001094998.1 TIGRFAM: bacterioferritin; PFAM: Ferritin, Dps family protein; KEGG: sdn:Sden_0990 bacterioferritin YP_001094999.1 PFAM: protein of unknown function DUF539; KEGG: shm:Shewmr7_0981 protein of unknown function DUF539 YP_001095000.1 PFAM: ApbE family lipoprotein; KEGG: she:Shewmr4_0942 ApbE family lipoprotein YP_001095001.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001095002.1 Part of the NQR complex which consists of NqrA, NqrB, NqrC, NqrD, NqrE and NqrF; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm; NqrE is probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. YP_001095003.1 Part of the NQR complex which catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm YP_001095004.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001095005.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001095006.1 uses the energy from reduction of ubiquinone-1 to ubiquinol to move Na(+) ions from the cytoplasm to the periplasm YP_001095007.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_001095008.1 PFAM: BolA family protein; KEGG: she:Shewmr4_0932 BolA family protein YP_001095009.1 KEGG: sfr:Sfri_3629 glycine cleavage system regulatory protein-like protein YP_001095010.1 KEGG: shm:Shewmr7_0969 2OG-Fe(II) oxygenase YP_001095011.1 PFAM: methyltransferase small; KEGG: shm:Shewmr7_0968 rRNA (guanine-N(2)-)-methyltransferase YP_001095012.1 KEGG: she:Shewmr4_3149 sterol desaturase family protein YP_001095013.1 KEGG: shm:Shewmr7_0817 hypothetical protein YP_001095014.1 PFAM: uncharacterized lipoprotein; KEGG: shm:Shewmr7_0815 uncharacterized lipoprotein YP_001095015.1 PFAM: peptidyl-prolyl cis-trans isomerase, cyclophilin type; KEGG: shm:Shewmr7_0814 peptidyl-prolyl cis-trans isomerase, cyclophilin type YP_001095016.1 KEGG: son:SO3813 hypothetical protein YP_001095017.1 PFAM: major facilitator superfamily MFS_1; KEGG: shm:Shewmr7_0812 major facilitator superfamily MFS_1 YP_001095018.1 putative nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_001095019.1 PFAM: VanZ family protein; KEGG: son:SO3816 hypothetical protein YP_001095020.1 KEGG: she:Shewmr4_3158 2-dehydropantoate 2-reductase; TIGRFAM: 2-dehydropantoate 2-reductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal domain protein; Ketopantoate reductase ApbA/PanE, C-terminal domain protein YP_001095021.1 PFAM: sodium:neurotransmitter symporter; KEGG: ppr:PBPRA1510 putative sodium-dependent transporter YP_001095022.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: vpa:VPA0041 transcriptional regulator, LysR family YP_001095023.1 PFAM: protein of unknown function DUF413; KEGG: vpa:VPA0040 hypothetical protein YP_001095024.1 The second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001095025.1 PFAM: protein of unknown function DUF1704; KEGG: vvy:VVA0030 hypothetical protein YP_001095026.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: gbe:GbCGDNIH1_2224 phosphoesterase, PAP2 family YP_001095027.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: sdn:Sden_3066 chemotaxis sensory transducer YP_001095028.1 KEGG: sfr:Sfri_0729 hypothetical protein YP_001095029.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_001095030.1 PFAM: protein of unknown function DUF819; KEGG: shm:Shewmr7_0802 protein of unknown function DUF819 YP_001095031.1 KEGG: shm:Shewmr7_0801 hypothetical protein YP_001095032.1 PFAM: Invasion gene expression up-regulator, SirB; KEGG: shm:Shewmr7_0800 invasion gene expression up-regulator, SirB YP_001095033.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: bur:Bcep18194_A5736 transcriptional regulator, LysR family YP_001095034.1 PFAM: GCN5-related N-acetyltransferase; KEGG: cps:CPS_2504 acetyltransferase, GNAT family YP_001095036.1 TIGRFAM: modification methylase, HemK family; PFAM: methyltransferase small; KEGG: shm:Shewmr7_0798 modification methylase, HemK family YP_001095037.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_001095038.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_001095039.1 PFAM: outer membrane lipoprotein LolB; KEGG: she:Shewmr4_3171 outer membrane lipoprotein LolB YP_001095040.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_001095041.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_001095044.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_001095045.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_001095046.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: shm:Shewmr7_1071 ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family YP_001095047.1 KEGG: shm:Shewmr7_1070 hypothetical protein YP_001095048.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_001095049.1 PFAM: PhoH family protein; KEGG: she:Shewmr4_1003 PhoH family protein YP_001095050.1 PFAM: protein of unknown function UPF0054; KEGG: sdn:Sden_0813 protein of unknown function UPF0054 YP_001095051.1 PFAM: CBS domain containing protein; transporter-associated region; KEGG: shm:Shewmr7_1066 CBS domain containing protein YP_001095052.1 Transfers the fatty acyl group on membrane lipoproteins YP_001095053.1 PFAM: protein of unknown function DUF1451; KEGG: shm:Shewmr7_1063 protein of unknown function DUF1451 YP_001095054.1 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase YP_001095055.1 PFAM: Rare lipoprotein B; KEGG: shm:Shewmr7_1061 rare lipoprotein B YP_001095056.1 KEGG: son:SO1172 DNA polymerase III delta subunit; TIGRFAM: DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta YP_001095057.1 KEGG: sfr:Sfri_0702 nicotinate (nicotinamide) nucleotide adenylyltransferase; TIGRFAM: cytidyltransferase-related domain protein; nicotinate (nicotinamide) nucleotide adenylyltransferase; PFAM: cytidylyltransferase YP_001095058.1 TIGRFAM: iojap-like protein; PFAM: Iojap-related protein; KEGG: shm:Shewmr7_1058 iojap-like protein YP_001095059.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_001095060.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: shm:Shewmr7_1056 peptidoglycan glycosyltransferase YP_001095061.1 TIGRFAM: rod shape-determining protein RodA; PFAM: cell cycle protein; KEGG: shm:Shewmr7_1055 rod shape-determining protein RodA YP_001095062.1 TIGRFAM: lytic murein transglycosylase B; KEGG: shm:Shewmr7_1054 lytic murein transglycosylase B YP_001095063.1 TIGRFAM: rare lipoprotein A; PFAM: Rare lipoprotein A; Sporulation domain protein; KEGG: sdn:Sden_0852 rare lipoprotein A YP_001095064.1 PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: she:Shewmr4_0987 serine-type D-Ala-D-Ala carboxypeptidase YP_001095065.1 PFAM: protein of unknown function DUF493; KEGG: shm:Shewmr7_1051 protein of unknown function DUF493 YP_001095066.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_001095067.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_001095068.1 TIGRFAM: ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase; FR47 domain protein; KEGG: sdn:Sden_2855 ribosomal-protein-alanine acetyltransferase YP_001095070.1 KEGG: shm:Shewmr7_3070 CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase YP_001095071.1 KEGG: shm:Shewmr7_3071 hypothetical protein YP_001095072.1 KEGG: ppr:PBPRA1913 hypothetical protein YP_001095073.1 PFAM: AAA ATPase, central domain protein; Clp N terminal domain protein; ATPase associated with various cellular activities, AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3072 ATPase AAA-2 domain protein YP_001095074.1 PFAM: protein of unknown function DUF152; KEGG: son:SO3578 conserved hypothetical protein TIGR00726 YP_001095075.1 KEGG: shm:Shewmr7_3074 pseudouridine synthase, RluA family; TIGRFAM: pseudouridine synthase, RluA family; PFAM: RNA-binding S4 domain protein; pseudouridine synthase YP_001095076.1 KEGG: shm:Shewmr7_3075 putative lipoprotein YP_001095077.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3076 methyl-accepting chemotaxis sensory transducer YP_001095078.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; CHASE4 domain protein; KEGG: sfr:Sfri_3981 diguanylate cyclase YP_001095079.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: she:Shewmr4_3174 methyl-accepting chemotaxis sensory transducer YP_001095080.1 catalyzes the formation of L-proline from L-ornithine YP_001095081.1 PFAM: sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: shm:Shewmr7_0791 RNA polymerase, sigma-24 subunit, ECF subfamily YP_001095082.1 KEGG: she:Shewmr4_3176 hypothetical protein YP_001095083.1 KEGG: she:Shewmr4_3177 hypothetical protein YP_001095084.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4542 transcriptional regulator, LysR family YP_001095085.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: son:SO4539 serine protease, subtilase family YP_001095087.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_001095088.1 PFAM: protein of unknown function DUF1456; KEGG: son:SO3852 hypothetical protein YP_001095089.1 PFAM: beta-lactamase; KEGG: shm:Shewmr7_3266 beta-lactamase YP_001095090.1 KEGG: she:Shewmr4_3186 putative manganese transporter YP_001095091.1 PFAM: membrane-flanked domain protein; KEGG: sfr:Sfri_0836 membrane-flanked domain protein YP_001095092.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3184 TonB-dependent receptor YP_001095093.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: she:Shewmr4_3183 glutathione S-transferase, N-terminal domain protein YP_001095094.1 KEGG: pha:PSHAa2040 hypothetical protein YP_001095095.1 KEGG: shm:Shewmr7_0784 hypothetical protein YP_001095096.1 KEGG: she:Shewmr4_3181 hypothetical protein YP_001095097.1 KEGG: son:SO3846 hypothetical protein YP_001095098.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_3179 endothelin-converting enzyme 1 YP_001095099.1 PFAM: transferase hexapeptide repeat containing protein; KEGG: vpa:VPA1135 putative acetyltransferase YP_001095100.1 PFAM: RNA-binding S4 domain protein; pseudouridine synthase; KEGG: shm:Shewmr7_0788 pseudouridine synthase, Rsu YP_001095101.1 KEGG: shm:Shewmr7_0775 hypothetical protein YP_001095102.1 KEGG: son:SO3859 cyclic nucleotide phosphodiesterase, putative; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; SMART: Tetratricopeptide domain protein YP_001095103.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO3860 hypothetical protein YP_001095104.1 TIGRFAM: putative iron-sulfur cluster binding protein; PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; domain of unknown function DUF1730; KEGG: shm:Shewmr7_0771 putative iron-sulfur cluster binding protein YP_001095105.1 PFAM: protein of unknown function DUF1458; KEGG: sfr:Sfri_0829 protein of unknown function DUF1458 YP_001095106.1 PFAM: beta-lactamase domain protein; KEGG: son:SO0357 metallo-beta-lactamase superfamily protein YP_001095107.1 PFAM: glucose-methanol-choline oxidoreductase; KEGG: cps:CPS_0109 hypothetical protein YP_001095108.1 KEGG: cps:CPS_0110 Tat (twin-arginine translocation) pathway signal sequence domain protein YP_001095109.1 PFAM: ferredoxin-dependent glutamate synthase; SMART: zinc finger, CDGSH-type domain protein; KEGG: cps:CPS_1903 glutamate synthase domain protein YP_001095110.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO4139 hypothetical protein YP_001095111.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_001095112.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: shm:Shewmr7_0653 transcriptional regulator, LysR family YP_001095113.1 PFAM: HDOD; KEGG: shm:Shewmr7_0652 putative signal transduction protein YP_001095114.1 PFAM: lipolytic enzyme, G-D-S-L family; KEGG: aeh:Mlg_0488 lipolytic enzyme, G-D-S-L family YP_001095115.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: son:SO0815 TonB-dependent receptor C-terminal domain protein YP_001095116.1 PFAM: protein of unknown function DUF805; KEGG: sfr:Sfri_4038 protein of unknown function DUF805 YP_001095117.1 PFAM: amidohydrolase; Amidohydrolase 3; KEGG: sfr:Sfri_0801 amidohydrolase YP_001095118.1 KEGG: she:Shewmr4_3303 hypothetical protein YP_001095119.1 PFAM: Penicillinase repressor; KEGG: sfr:Sfri_3585 transcriptional repressor, CopY family protein YP_001095120.1 TIGRFAM: TonB family protein; PFAM: Gram-negative tonB protein; peptidase M56, BlaR1; KEGG: sfr:Sfri_3584 TonB family protein YP_001095121.1 KEGG: cps:CPS_0549 hypothetical protein YP_001095122.1 KEGG: cps:CPS_0544 hypothetical protein YP_001095123.1 PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: sdn:Sden_0949 uroporphyrin-III C/tetrapyrrole (corrin/porphyrin) methyltransferase YP_001095124.1 KEGG: cps:CPS_0547 hypothetical protein YP_001095125.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: cps:CPS_0546 GGDEF domain protein YP_001095126.1 SMART: extracellular solute-binding protein, family 3; KEGG: cps:CPS_4167 sodium:dicarboxylate symporter family/bacterial extracellular solute-binding family 3 protein YP_001095127.1 KEGG: she:Shewmr4_2079 hypothetical protein YP_001095128.1 functions in fatty acid oxidation; converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA YP_001095129.1 PFAM: protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: shm:Shewmr7_2809 protein of unknown function DUF224, cysteine-rich region domain protein YP_001095130.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_2810 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001095131.1 KEGG: son:SO1518 hypothetical protein YP_001095132.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sfr:Sfri_1855 transcriptional regulator, LysR family protein YP_001095133.1 PFAM: PpiC-type peptidyl-prolyl cis-trans isomerase; KEGG: par:Psyc_0857 peptidylprolyl isomerase YP_001095134.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein YP_001095135.1 KEGG: ppr:PBPRB0920 hypothetical protein YP_001095136.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: noc:Noc_1840 divalent cation transporter YP_001095137.1 PFAM: MscS Mechanosensitive ion channel; KEGG: sdn:Sden_1606 MscS mechanosensitive ion channel YP_001095138.1 TIGRFAM: SSS sodium solute transporter superfamily; sodium/proline symporter; PFAM: Na+/solute symporter; KEGG: sfr:Sfri_0764 sodium/proline symporter YP_001095139.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_001095140.1 TIGRFAM: gamma-glutamyl phosphate reductase; KEGG: shm:Shewmr7_3942 gamma-glutamyl phosphate reductase YP_001095141.1 KEGG: sfr:Sfri_0761 pyrroline-5-carboxylate reductase; TIGRFAM: pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent YP_001095142.1 PFAM: glycerophosphoryl diester phosphodiesterase; KEGG: she:Shewmr4_3310 glycerophosphoryl diester phosphodiesterase YP_001095143.1 PFAM: alpha/beta hydrolase fold; KEGG: sfr:Sfri_0775 alpha/beta hydrolase fold YP_001095144.1 KEGG: sfr:Sfri_0774 zinc carboxypeptidase-related protein YP_001095145.1 KEGG: pfo:Pfl_4744 hypothetical protein YP_001095146.1 PFAM: peptidase domain protein; Endonuclease I; KEGG: sdn:Sden_3289 endonuclease I YP_001095147.1 KEGG: son:SO2798 hypothetical protein YP_001095148.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: sfr:Sfri_0758 diguanylate cyclase YP_001095149.1 PFAM: Amidohydrolase 3; KEGG: sdn:Sden_0948 amidohydrolase 3 YP_001095150.1 KEGG: she:Shewmr4_3207 hypothetical protein YP_001095151.1 KEGG: she:Shewmr4_3206 hypothetical protein YP_001095152.1 KEGG: tbd:Tbd_1307 hypothetical protein YP_001095153.1 PFAM: phospholipase D/Transphosphatidylase; KEGG: sdn:Sden_1075 phospholipase D/transphosphatidylase YP_001095154.1 PFAM: protein of unknown function DUF985; KEGG: she:Shewmr4_3317 protein of unknown function DUF985 YP_001095155.1 KEGG: sfr:Sfri_0741 hypothetical protein YP_001095156.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: ppr:PBPRB1965 putative PAP2 family protein YP_001095158.1 TIGRFAM: uncharacterized domain; PFAM: OsmC family protein; protein of unknown function DUF181; KEGG: she:Shewmr4_3321 uncharacterized domain YP_001095159.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: tcx:Tcr_0397 diguanylate cyclase (GGDEF domain) YP_001095160.1 KEGG: son:SO0793 hypothetical protein YP_001095161.1 KEGG: sdn:Sden_3769 hypothetical protein YP_001095162.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: RimK domain protein ATP-grasp; KEGG: sdn:Sden_3770 S6 modification enzyme RimK YP_001095163.1 TIGRFAM: asparagine synthase (glutamine-hydrolyzing); PFAM: glutamine amidotransferase, class-II; asparagine synthase; KEGG: sdn:Sden_3771 asparagine synthase, glutamine-hydrolyzing YP_001095164.1 PFAM: protein of unknown function DUF159; KEGG: sdn:Sden_3234 protein of unknown function DUF159 YP_001095167.1 KEGG: shm:Shewmr7_0629 hypothetical protein YP_001095168.1 KEGG: cps:CPS_2512 hypothetical protein YP_001095169.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: ppr:PBPRB0028 hypothetical methyl-accepting chemotaxisprotein YP_001095170.1 KEGG: son:SO3714 sugar-binding protein, putative YP_001095171.1 PFAM: Carboxymuconolactone decarboxylase; KEGG: ypn:YPN_1479 decarboxylase YP_001095172.1 KEGG: rso:RSc0206 hypothetical signal peptide protein YP_001095173.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pfl:PFL_2420 D-isomer specific 2-hydroxyacid dehydrogenase family protein YP_001095174.1 PFAM: major facilitator superfamily MFS_1; KEGG: mmp:MMP0797 general substrate transporter YP_001095175.1 KEGG: rso:RSc0630 hypothetical protein YP_001095176.1 PFAM: Cupin 2, conserved barrel domain protein; KEGG: rfr:Rfer_2441 carboxymuconolactone decarboxylase YP_001095177.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC-type transcriptional regulator domain protein; KEGG: rso:RSc0625 probable transcription regulator protein YP_001095178.1 PFAM: beta-lactamase; KEGG: bur:Bcep18194_C7182 serine-type D-Ala-D-Ala carboxypeptidase YP_001095179.1 KEGG: abo:ABO_1660 hypothetical protein YP_001095180.1 PFAM: CMP/dCMP deaminase, zinc-binding; KEGG: sfr:Sfri_3571 CMP/dCMP deaminase, zinc-binding YP_001095181.1 KEGG: ilo:IL1589 hypothetical protein YP_001095183.1 PFAM: beta-lactamase; KEGG: mxa:MXAN_6409 putative beta-lactamase YP_001095184.1 KEGG: cps:CPS_4414 hypothetical protein YP_001095185.1 KEGG: she:Shewmr4_3416 hypothetical protein YP_001095187.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_001095188.1 part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor YP_001095189.1 catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein YP_001095190.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: son:SO0778 oxidoreductase, FAD-binding, UbiH/Coq6 family YP_001095191.1 TIGRFAM: Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; 2-polyprenyl-6-methoxyphenol 4-hydroxylase; PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: she:Shewmr4_3333 2-polyprenyl-6-methoxyphenol 4-hydroxylase YP_001095192.1 TIGRFAM: yecA family protein; PFAM: protein of unknown function UPF0149; KEGG: shm:Shewmr7_0619 YecA family protein YP_001095193.1 PFAM: protein of unknown function DUF710; KEGG: son:SO0775 hypothetical protein YP_001095194.1 PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: shm:Shewmr7_0617 5-formyltetrahydrofolate cyclo-ligase YP_001095195.1 SMART: extracellular solute-binding protein, family 3; KEGG: son:SO3481 hypothetical protein YP_001095196.1 KEGG: son:SO3163 lipoprotein YP_001095197.1 KEGG: reu:Reut_A0537 cold-shock protein, DNA-binding YP_001095198.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_001095199.1 KEGG: son:SO3655 pilin, putative YP_001095200.1 KEGG: son:SO3656 hypothetical protein YP_001095201.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_3132 lysine exporter protein (LysE/YggA) YP_001095202.1 PFAM: peptidase S10, serine carboxypeptidase; KEGG: she:Shewmr4_0889 peptidase S10, serine carboxypeptidase YP_001095203.1 PFAM: Ppx/GppA phosphatase; KEGG: she:Shewmr4_2208 Ppx/GppA phosphatase YP_001095204.1 PFAM: Polyphosphate kinase; KEGG: shm:Shewmr7_2284 polyphosphate kinase YP_001095205.1 KEGG: sfr:Sfri_3095 thiol:disulfide interchange protein, putative YP_001095206.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3096 TonB-dependent receptor YP_001095207.1 KEGG: she:Shewmr4_0887 transcriptional regulator, fis family; TIGRFAM: PAS sensor protein; PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; AAA ATPase YP_001095208.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: shm:Shewmr7_3136 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001095209.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_3139 AMP-dependent synthetase and ligase YP_001095210.1 PFAM: Lipocalin family protein; KEGG: pat:Patl_0580 lipocalin-like YP_001095211.1 KEGG: sfr:Sfri_3610 hypothetical protein YP_001095212.1 KEGG: son:SO3665 ABC transporter, ATP-binding/permease protein, putative; TIGRFAM: lipid A ABC exporter family, fused ATPase and inner membrane subunits; PFAM: ABC transporter, transmembrane region; ABC transporter-related protein; SMART: AAA ATPase YP_001095213.1 PFAM: short chain fatty acid transporter; KEGG: shm:Shewmr7_2886 short chain fatty acid transporter YP_001095214.1 KEGG: cps:CPS_1442 hypothetical protein YP_001095215.1 KEGG: sfr:Sfri_0942 hypothetical protein YP_001095216.1 PFAM: membrane-flanked domain protein; KEGG: sfr:Sfri_0941 membrane-flanked domain protein YP_001095217.1 PFAM: membrane-flanked domain protein; KEGG: sfr:Sfri_0940 membrane-flanked domain protein YP_001095218.1 PFAM: protein of unknown function DUF924; KEGG: she:Shewmr4_0877 protein of unknown function DUF924 YP_001095219.1 PFAM: protein of unknown function DUF81; KEGG: ppr:PBPRA2195 hypothetical protein YP_001095221.1 KEGG: gvi:gll1663 metalloprotease MEP1 homolog YP_001095222.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: sfr:Sfri_3717 TonB-dependent siderophore receptor YP_001095223.1 PFAM: NADH:flavin oxidoreductase/NADH oxidase; KEGG: ppr:PBPRB1366 putative NADH-dependent flavin oxidoreductase YP_001095224.1 PFAM: regulatory protein, TetR; KEGG: she:Shewmr4_1157 transcriptional regulator, TetR family YP_001095225.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0938 UspA domain protein YP_001095226.1 PFAM: UspA domain protein; KEGG: sfr:Sfri_0938 UspA domain protein YP_001095227.1 KEGG: she:Shewmr4_0873 hypothetical protein YP_001095228.1 PFAM: aldehyde dehydrogenase; KEGG: son:SO3683 coniferyl aldehyde dehydrogenase YP_001095229.1 PFAM: regulatory protein, TetR; KEGG: son:SO3684 transcriptional regulator, TetR family YP_001095230.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: pat:Patl_2651 transcriptional regulator, LysR family YP_001095231.1 PFAM: ThiJ/PfpI domain protein; KEGG: pat:Patl_2650 ThiJ/PfpI YP_001095232.1 PFAM: peptidase M19, renal dipeptidase; KEGG: shm:Shewmr7_0834 twin-arginine translocation pathway signal YP_001095234.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: shm:Shewmr7_1975 protein of unknown function DUF6, transmembrane YP_001095236.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; KEGG: ppr:PBPRB1065 hypothetical oxidoreductase protein YP_001095237.1 KEGG: sfr:Sfri_3690 flavocytochrome c; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase YP_001095238.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; SMART: extracellular solute-binding protein, family 3; KEGG: sfr:Sfri_3689 periplasmic sensor signal transduction histidine kinase YP_001095239.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; SMART: AAA ATPase; KEGG: sfr:Sfri_3688 two component, sigma54 specific, transcriptional regulator, fis family protein YP_001095240.1 PFAM: sodium:dicarboxylate symporter; KEGG: sdn:Sden_2987 sodium:dicarboxylate symporter YP_001095241.1 KEGG: shm:Shewmr7_3380 hypothetical protein YP_001095242.1 KEGG: sfr:Sfri_0526 hypothetical protein YP_001095243.1 KEGG: she:Shewmr4_0638 hypothetical protein YP_001095244.1 KEGG: son:SO4011 hypothetical protein YP_001095245.1 PFAM: phosphate-selective porin O and P; KEGG: sdn:Sden_0638 phosphate-selective porin O and P YP_001095246.1 KEGG: sdn:Sden_0639 FMN-binding YP_001095247.1 PFAM: PepSY-associated TM helix domain protein; KEGG: sdn:Sden_0640 PepSY-associated TM helix YP_001095248.1 KEGG: shm:Shewmr7_3406 penicillin-binding protein 1B; TIGRFAM: penicillin-binding protein 1B; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase YP_001095249.1 KEGG: shm:Shewmr7_3407 ATP-dependent helicase HrpB; TIGRFAM: ATP-dependent helicase HrpB; PFAM: helicase domain protein; helicase-associated domain protein; DEAD/DEAH box helicase domain protein; Helicase ATP-dependent, C-terminal domain protein; SMART: DEAD-like helicases-like YP_001095250.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: shm:Shewmr7_3409 diguanylate cyclase/phosphodiesterase YP_001095251.1 TIGRFAM: 2'-5' RNA ligase; PFAM: 2',5' RNA ligase; KEGG: shm:Shewmr7_3410 2'-5' RNA ligase YP_001095252.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_001095253.1 Regulatory factor involved in maltose metabolism YP_001095254.1 TIGRFAM: RNA polymerase-binding protein DksA; PFAM: zinc finger, DksA/TraR C4-type; KEGG: shm:Shewmr7_3292 transcriptional regulators, TraR/DksA family YP_001095255.1 PFAM: glutamyl-tRNA synthetase, class Ic; KEGG: shm:Shewmr7_3293 glutamyl-tRNA synthetase, class Ic YP_001095256.1 TIGRFAM: poly(A) polymerase; PFAM: Polynucleotide adenylyltransferase region; KEGG: son:SO0872 tRNA nucleotidyltransferase (CCA-adding enzyme) YP_001095257.1 KEGG: shm:Shewmr7_3295 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK YP_001095258.1 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate YP_001095259.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_001095260.1 PFAM: L-lactate permease; KEGG: shm:Shewmr7_2807 L-lactate permease YP_001095261.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; FAD linked oxidase domain protein; KEGG: she:Shewmr4_2735 FAD linked oxidase domain protein YP_001095262.1 KEGG: she:Shewmr4_0724 hypothetical protein YP_001095265.1 PFAM: ABC-2 type transporter; KEGG: son:SO3801 ABC transporter, permease protein YP_001095266.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0823 ABC transporter-related protein YP_001095267.1 KEGG: shm:Shewmr7_0822 hypoxanthine phosphoribosyltransferase; TIGRFAM: hypoxanthine phosphoribosyltransferase; PFAM: phosphoribosyltransferase YP_001095268.1 TIGRFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: flavoprotein; KEGG: shm:Shewmr7_0821 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_001095269.1 TIGRFAM: UDP-N-acetylmuramate; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: shm:Shewmr7_0820 UDP-N-acetylmuramate YP_001095270.1 KEGG: cps:CPS_0193 hypothetical protein YP_001095272.1 KEGG: sdn:Sden_3258 hypothetical protein YP_001095273.1 PFAM: regulatory protein, MarR; KEGG: rso:RSc1851 putative transcription regulator protein YP_001095274.1 KEGG: sil:SPO1325 lipoprotein, putative YP_001095275.1 PFAM: Antibiotic biosynthesis monooxygenase; KEGG: ppr:PBPRA1783 hypothetical protein YP_001095276.1 KEGG: sfr:Sfri_0187 hypothetical protein YP_001095277.1 PFAM: peptidase S8 and S53, subtilisin, kexin, sedolisin; protease-associated PA domain protein; KEGG: shm:Shewmr7_3529 peptidase S8 and S53, subtilisin, kexin, sedolisin YP_001095278.1 PFAM: regulatory protein, LysR; KEGG: she:Shewmr4_2072 transcriptional regulator, LysR family YP_001095279.1 PFAM: regulatory protein, LysR; KEGG: shm:Shewmr7_3839 transcriptional regulator, LysR family YP_001095280.1 KEGG: shm:Shewmr7_3838 hypothetical protein YP_001095281.1 KEGG: sfr:Sfri_0615 hypothetical protein YP_001095282.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfr:Sfri_0614 twin-arginine translocation pathway signal YP_001095283.1 PFAM: Polysulphide reductase, NrfD; KEGG: shm:Shewmr7_3835 polysulphide reductase, NrfD YP_001095284.1 KEGG: cps:CPS_4482 Bax domain protein YP_001095286.1 KEGG: son:SO0403 hypothetical protein YP_001095287.1 KEGG: son:SO0404 hypothetical protein YP_001095288.1 KEGG: she:Shewmr4_0458 diguanylate cyclase with PAS/PAC sensor; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; PAS fold-3 domain protein; SMART: PAC repeat-containing protein YP_001095289.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0917 ABC transporter-related protein YP_001095290.1 TIGRFAM: polar amino acid ABC transporter, inner membrane subunit; PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: she:Shewmr4_3054 polar amino acid ABC transporter, inner membrane subunit YP_001095291.1 PFAM: extracellular solute-binding protein, family 3; SMART: ionotropic glutamate receptor; KEGG: son:SO1044 amino acid ABC transporter, periplasmic amino acid-binding protein YP_001095292.1 KEGG: son:SO3972 hypothetical transposase YP_001095293.1 PFAM: protein of unknown function DUF541; KEGG: shm:Shewmr7_0500 protein of unknown function DUF541 YP_001095294.1 KEGG: sfr:Sfri_0588 WD-40 repeat protein YP_001095295.1 PFAM: sodium/hydrogen exchanger; KEGG: sfr:Sfri_3583 sodium/hydrogen exchanger YP_001095296.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_001095297.1 KEGG: cps:CPS_4664 4-aminobutyrate aminotransferase; TIGRFAM: 4-aminobutyrate aminotransferase; PFAM: aminotransferase class-III YP_001095298.1 KEGG: cps:CPS_2023 succinate-semialdehyde dehydrogenase; TIGRFAM: succinic semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase YP_001095299.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: cps:CPS_4666 transcriptional regulator, LysR family YP_001095300.1 PFAM: outer membrane porin; KEGG: shm:Shewmr7_2788 outer membrane porin YP_001095301.1 PFAM: regulatory protein GntR, HTH; GntR domain protein; KEGG: sfr:Sfri_3695 regulatory protein GntR, HTH YP_001095302.1 KEGG: son:SO1504 hypothetical protein YP_001095303.1 PFAM: Na+/H+ antiporter NhaC; KEGG: shm:Shewmr7_0954 Na+/H+ antiporter NhaC YP_001095304.1 KEGG: shm:Shewmr7_0953 hypothetical protein YP_001095305.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0952 pseudouridine synthase, Rsu YP_001095306.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; KEGG: shm:Shewmr7_2787 twin-arginine translocation pathway signal YP_001095307.1 KEGG: sfr:Sfri_3693 hypothetical protein YP_001095310.1 KEGG: ecs:ECs0400 hypothetical protein YP_001095311.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: eca:ECA2247 Arac-family transcriptional regulator YP_001095312.1 KEGG: shm:Shewmr7_0949 hypothetical protein YP_001095313.1 PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: sfr:Sfri_0574 aromatic amino acid permease YP_001095314.1 PFAM: protein of unknown function UPF0016; KEGG: she:Shewmr4_3028 protein of unknown function UPF0016 YP_001095315.1 PFAM: Catalase domain protein; KEGG: son:SO1070 catalase YP_001095316.1 KEGG: sdn:Sden_3091 hypothetical protein YP_001095317.1 TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: shm:Shewmr7_0943 uncharacterized domain 1 protein YP_001095318.1 PFAM: Endonuclease/exonuclease/phosphatase; KEGG: she:Shewmr4_3033 endonuclease/exonuclease/phosphatase YP_001095319.1 PFAM: regulatory protein, LuxR; sigma-70 region 4 domain protein; Sigma-70, region 4 type 2; KEGG: sdn:Sden_3096 regulatory protein, LuxR YP_001095320.1 KEGG: she:Shewmr4_0719 hypothetical protein YP_001095321.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_001095323.1 PFAM: glycine cleavage T protein (aminomethyl transferase); KEGG: she:Shewmr4_0717 glycine cleavage T protein (aminomethyl transferase) YP_001095324.1 PFAM: response regulator receiver; metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3306 response regulator receiver modulated metal dependent phosphohydrolase YP_001095325.1 KEGG: son:SO0859 sensory box histidine kinase/response regulator; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001095326.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: she:Shewmr4_0713 ABC transporter-related protein YP_001095327.1 PFAM: protein of unknown function DUF214; KEGG: son:SO0856 putative ABC transport system permease protein YP_001095328.1 KEGG: she:Shewmr4_0711 hypothetical protein YP_001095329.1 PFAM: cytochrome B561; KEGG: she:Shewmr4_0244 cytochrome b561 YP_001095330.1 PFAM: NapD family protein; KEGG: shm:Shewmr7_3317 NapD family protein YP_001095331.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_001095332.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_001095333.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_001095334.1 PFAM: Nitrate reductase cytochrome c-type subunit (NapB); KEGG: shm:Shewmr7_3321 nitrate reductase cytochrome c-type subunit (NapB) YP_001095336.1 PFAM: Glutathione S-transferase, N-terminal domain; Glutathione S-transferase, C-terminal domain; KEGG: pat:Patl_0196 glutathione S-transferase-like YP_001095337.1 KEGG: sde:Sde_1847 cell division protein ZipA YP_001095338.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: vpa:VPA0104 putative ring-cleaving dioxygenase YP_001095339.1 KEGG: she:Shewmr4_2212 hypothetical protein YP_001095340.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: mes:Meso_2232 ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_001095341.1 KEGG: sfr:Sfri_2734 hypothetical protein YP_001095342.1 PFAM: sodium/hydrogen exchanger; KEGG: pcu:pc0094 putative Na(+)/H(+) antiporter YP_001095343.1 PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: she:Shewmr4_0696 carbamoyl-phosphate synthase L chain, ATP-binding YP_001095344.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: she:Shewmr4_0695 transcriptional regulator, LysR family YP_001095345.1 PFAM: penicillin-binding protein, transpeptidase; KEGG: shm:Shewmr7_3328 beta-lactamase YP_001095346.1 KEGG: sfr:Sfri_0546 hypothetical protein YP_001095347.1 PFAM: protein of unknown function DUF335, SprT; SMART: protein of unknown function SprT; KEGG: son:SO0834 sprT protein, putative YP_001095348.1 PFAM: Endonuclease I; KEGG: she:Shewmr4_0691 deoxyribonuclease I YP_001095349.1 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase YP_001095350.1 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione YP_001095351.1 PFAM: Alkaline phosphatase; KEGG: she:Shewmr4_0688 alkaline phosphatase YP_001095352.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; KEGG: cps:CPS_0952 GGDEF/EAL domain protein YP_001095353.1 KEGG: net:Neut_1424 conserved hypothetical protein YP_001095354.1 KEGG: noc:Noc_1149 hypothetical protein YP_001095355.1 PFAM: methyltransferase small; Methyltransferase type 11; Methyltransferase type 12; Methyltransferase small, N-terminal domain protein; KEGG: she:Shewmr4_0687 rRNA (guanine-N(2)-)-methyltransferase YP_001095356.1 PFAM: protein of unknown function DUF342; KEGG: shm:Shewmr7_0674 protein of unknown function DUF342 YP_001095357.1 PFAM: peptidase M50; KEGG: she:Shewmr4_3275 peptidase M50 YP_001095358.1 PFAM: cyclic nucleotide-binding; regulatory protein, Crp; KEGG: pae:PA1544 transcriptional regulator Anr YP_001095359.1 KEGG: cya:CYA_0280 thrombospondin N-terminal-like domain protein YP_001095360.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: mes:Meso_2223 multi-sensor signal transduction histidine kinase YP_001095362.1 PFAM: Na-Ca exchanger/integrin-beta4; KEGG: aba:Acid345_1066 hypothetical protein YP_001095364.1 PFAM: Na-Ca exchanger/integrin-beta4; KEGG: aba:Acid345_1066 hypothetical protein YP_001095365.1 PFAM: regulatory protein, LuxR; response regulator receiver; Sigma-70, region 4 type 2; KEGG: dar:Daro_3108 regulatory protein, LuxR:response regulator receiver YP_001095366.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: abo:ABO_2371 TonB-dependent receptor protein YP_001095367.1 PFAM: regulatory protein, LysR; KEGG: shm:Shewmr7_0288 transcriptional regulator, LysR family YP_001095368.1 PFAM: molydopterin dinucleotide-binding region; KEGG: ppr:PBPRB1372 hypothetical tetrathionate reductase YP_001095369.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: vpa:VP2011 tetrathionate reductase, subunit B YP_001095370.1 PFAM: Polysulphide reductase, NrfD; KEGG: eba:ebA1013 molybdenum enzyme of unknown function, small subunit, membrane anchor YP_001095371.1 KEGG: sfr:Sfri_3533 hypothetical protein YP_001095372.1 KEGG: sfr:Sfri_0507 hypothetical protein YP_001095373.1 KEGG: shm:Shewmr7_0765 hypothetical protein YP_001095374.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; KEGG: son:SO3894 sensor histidine kinase YP_001095375.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_001095376.1 PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: she:Shewmr4_3226 UBA/ThiF-type NAD/FAD binding protein YP_001095377.1 PFAM: porin, Gram-negative type; KEGG: she:Shewmr4_3227 outer membrane porin, putative YP_001095379.1 KEGG: sde:Sde_1944 cytochrome c family protein YP_001095380.1 KEGG: ddi:DDB0217895 hypothetical protein YP_001095381.1 PFAM: copper resistance B precursor; KEGG: pha:PSHAb0010 copper resistance protein B [precursor] (CPx-type copper ATPase) YP_001095382.1 TIGRFAM: copper-resistance protein, CopA family; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3; KEGG: sde:Sde_1947 putative copper resistance transmembrane protein YP_001095383.1 TIGRFAM: heavy metal response regulator; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: pha:PSHAb0012 transcriptional activator of copper resistance (two-component regulatory system with CusS) YP_001095384.1 TIGRFAM: heavy metal sensor kinase; PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sde:Sde_1949 putative 2-component sensor protein YP_001095385.1 PFAM: porin, Gram-negative type; KEGG: sfr:Sfri_0503 porin, gram-negative type YP_001095386.1 catalyzes the S-adenosylmethionine-dependent transmethylation of thiopurine compounds; may be involved in selenium cycling by forming dimethylselenide and/or dimethyldiselenide YP_001095387.1 KEGG: shm:Shewmr7_3450 hypothetical protein YP_001095388.1 PFAM: protein kinase; SMART: serine/threonine protein kinase; KEGG: she:Shewmr4_0579 serine/threonine protein kinase YP_001095389.1 PFAM: FxsA cytoplasmic membrane protein; KEGG: shm:Shewmr7_0548 FxsA cytoplasmic membrane protein YP_001095390.1 PFAM: CutA1 divalent ion tolerance protein; KEGG: shm:Shewmr7_0547 CutA1 divalent ion tolerance protein YP_001095391.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_001095392.1 PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: shm:Shewmr7_0545 sodium/hydrogen exchanger YP_001095393.1 KEGG: eli:ELI_02225 hypothetical protein YP_001095394.1 PFAM: glycoside hydrolase, family 42, domain 5, loop region; glycoside hydrolase family 2, immunoglobulin domain protein beta-sandwich; glycoside hydrolase family 2, TIM barrel; glycoside hydrolase family 2, sugar binding; KEGG: tma:TM1193 beta-galactosidase YP_001095395.1 TIGRFAM: SSS sodium solute transporter superfamily; PFAM: Na+/solute symporter; KEGG: pat:Patl_3683 SSS sodium solute transporter superfamily YP_001095396.1 TIGRFAM: galactokinase; PFAM: GHMP kinase; GHMP kinase, C terminal domain protein; KEGG: she:Shewmr4_3408 galactokinase YP_001095397.1 PFAM: Aldose 1-epimerase; KEGG: son:SO0693 aldose 1-epimerase YP_001095398.1 KEGG: she:Shewmr4_3410 hypothetical protein YP_001095399.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: son:SO0640 alcohol dehydrogenase, zinc-containing YP_001095400.1 PFAM: CheC domain protein; KEGG: sfr:Sfri_3344 CheC domain protein YP_001095401.1 KEGG: vpa:VP2733 hypothetical protein YP_001095402.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_001095403.1 KEGG: shm:Shewmr7_0692 replicative DNA helicase; TIGRFAM: replicative DNA helicase; PFAM: DnaB domain protein helicase, N-terminal domain protein; DnaB domain protein helicase, C-terminal domain protein; SMART: AAA ATPase YP_001095404.1 KEGG: shm:Shewmr7_0691 hypothetical protein YP_001095406.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_001095407.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_001095408.1 KEGG: sdn:Sden_0516 single-strand binding protein/primosomal replication protein N YP_001095409.1 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21 YP_001095410.1 PFAM: protein of unknown function DUF481; KEGG: she:Shewmr4_3261 protein of unknown function DUF481 YP_001095413.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_001095414.1 KEGG: she:Shewmr4_3264 ribonuclease R; TIGRFAM: VacB and RNase II family 3'-5' exoribonucleases; ribonuclease R; PFAM: ribonuclease II; RNA binding S1 domain protein; Ribonuclease B, OB region N-terminal domain; Ribonuclease R winged-helix domain protein; SMART: Cold shock protein YP_001095415.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO3936 sodium-type flagellar protein MotX YP_001095416.1 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis YP_001095417.1 KEGG: sdn:Sden_0508 hypothetical protein YP_001095418.1 forms a direct contact with the tRNA during translation YP_001095419.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_001095420.1 PFAM: AFG1-family ATPase; KEGG: sfr:Sfri_3361 AFG1-family ATPase YP_001095421.1 TIGRFAM: protease Do; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: she:Shewmr4_3271 protease Do YP_001095422.1 TIGRFAM: periplasmic serine protease DegS; PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: son:SO3943 protease DegS YP_001095423.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_001095424.1 PFAM: BolA family protein; KEGG: shm:Shewmr7_3338 BolA family protein YP_001095425.1 PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: shm:Shewmr7_3339 SpoIIAA family protein YP_001095426.1 PFAM: toluene tolerance family protein; KEGG: she:Shewmr4_0682 toluene tolerance family protein YP_001095427.1 PFAM: Mammalian cell entry related domain protein; KEGG: shm:Shewmr7_3341 mammalian cell entry related domain protein YP_001095428.1 PFAM: protein of unknown function DUF140; KEGG: son:SO3953 putative membrane protein YP_001095429.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3343 ABC transporter-related protein YP_001095430.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: sdn:Sden_0495 K+-dependent Na+/Ca+ exchanger related-protein YP_001095431.1 KEGG: shm:Shewmr7_3344 KpsF/GutQ family protein; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS) YP_001095432.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_001095433.1 PFAM: protein of unknown function DUF1239; KEGG: son:SO3958 hypothetical protein YP_001095434.1 PFAM: OstA family protein; KEGG: shm:Shewmr7_3347 OstA family protein YP_001095435.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_3348 ABC transporter-related protein YP_001095436.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen YP_001095437.1 TIGRFAM: ribosomal subunit interface protein; PFAM: sigma 54 modulation protein/ribosomal protein S30EA; KEGG: shm:Shewmr7_3350 sigma 54 modulation protein/ribosomal protein S30EA YP_001095438.1 TIGRFAM: PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; KEGG: shm:Shewmr7_3351 PTS IIA-like nitrogen-regulatory protein PtsN YP_001095439.1 PFAM: uncharacterized P-loop ATPase protein UPF0042; KEGG: shm:Shewmr7_3352 uncharacterized P-loop ATPase protein UPF0042 YP_001095440.1 TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: she:Shewmr4_0669 phosphocarrier, HPr family YP_001095441.1 TIGRFAM: magnesium transporter; PFAM: CBS domain containing protein; MgtE integral membrane region; MgtE intracellular region; KEGG: son:SO3966 magnesium transporter YP_001095442.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: vpa:VP1983 putaive two-component response regulator YP_001095443.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: vpa:VP1984 putative two-component sensor YP_001095445.1 KEGG: cps:CPS_0069 putative FG-GAP repeat lipoprotein YP_001095446.1 PFAM: protein of unknown function DUF752; KEGG: chu:CHU_0640 hypothetical protein YP_001095447.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: ppr:PBPRB1503 hypothetical membrane protein YP_001095448.1 KEGG: syn:sll1969 lipase homolog YP_001095449.1 KEGG: sdn:Sden_3286 hypothetical protein YP_001095450.1 PFAM: major facilitator superfamily MFS_1; KEGG: pha:PSHAa1259 transport protein of the major facilitator YP_001095451.1 PFAM: sodium/hydrogen exchanger; KEGG: hch:HCH_01176 NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain YP_001095452.1 PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: shm:Shewmr7_3492 RNA-metabolising metallo-beta-lactamase YP_001095453.1 PFAM: Ig domain protein, group 2 domain protein; Kelch repeat-containing protein; KEGG: hch:HCH_00094 cell wall surface anchor family protein YP_001095454.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; KEGG: shm:Shewmr7_3362 diguanylate cyclase/phosphodiesterase with GAF sensor YP_001095455.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; KEGG: son:SO4425 GGDEF family protein YP_001095456.1 PFAM: cyclic nucleotide-binding; SMART: regulatory protein, Crp; KEGG: sdn:Sden_3444 cyclic nucleotide-binding YP_001095457.1 PFAM: protein of unknown function DUF461; KEGG: sdn:Sden_3479 protein of unknown function DUF461 YP_001095458.1 PFAM: electron transport protein SCO1/SenC; KEGG: sdn:Sden_3480 electron transport protein SCO1/SenC YP_001095459.1 KEGG: sdn:Sden_3481 hypothetical protein YP_001095460.1 KEGG: sdn:Sden_3482 nitrite reductase, copper containing; TIGRFAM: nitrite reductase, copper-containing; PFAM: multicopper oxidase, type 1; multicopper oxidase, type 2; multicopper oxidase, type 3 YP_001095461.1 PFAM: regulatory protein, MarR; KEGG: sfr:Sfri_3643 transcriptional regulator, MarR family protein YP_001095462.1 PFAM: protein of unknown function DUF6, transmembrane; KEGG: sfr:Sfri_3644 protein of unknown function DUF6, transmembrane YP_001095463.1 PFAM: TOBE domain protein; KEGG: she:Shewmr4_2490 molybdenum-pterin binding YP_001095464.1 PFAM: glutathione-dependent formaldehyde-activating, GFA; KEGG: hch:HCH_10005 hypothetical protein YP_001095465.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: cps:CPS_0484 TonB-dependent receptor YP_001095466.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: vfi:VF2362 GGDEF family protein YP_001095467.1 PFAM: response regulator receiver; helix-turn-helix, Fis-type; KEGG: she:Shewmr4_3529 response regulator receiver protein YP_001095468.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3530 periplasmic sensor signal transduction histidine kinase YP_001095469.1 PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: shm:Shewmr7_0424 dTDP-4-dehydrorhamnose reductase YP_001095470.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_001095471.1 KEGG: shm:Shewmr7_0108 hypothetical protein YP_001095472.1 KEGG: she:Shewmr4_3532 hypothetical protein YP_001095473.1 PFAM: pseudouridine synthase; KEGG: shm:Shewmr7_0418 pseudouridine synthase YP_001095474.1 KEGG: son:SO4182 ATP-dependent protease La (LON) domain protein, putative YP_001095475.1 KEGG: shm:Shewmr7_0416 hypothetical protein YP_001095477.1 KEGG: pha:PSHAa1736 hypothetical protein YP_001095478.1 PFAM: conserved hypothetical protein 22; KEGG: sfr:Sfri_3560 conserved hypothetical protein 22 YP_001095479.1 PFAM: aminotransferase, class V; beta-lactamase domain protein; SMART: Rhodanese domain protein; KEGG: cps:CPS_0838 aminotransferase, class V YP_001095480.1 KEGG: cps:CPS_3938 hypothetical protein YP_001095481.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3513 heavy metal efflux pump, CzcA family YP_001095482.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: sdn:Sden_0575 secretion protein HlyD YP_001095483.1 KEGG: son:SO0518 outer membrane efflux family protein, putative YP_001095484.1 KEGG: sfr:Sfri_3589 hypothetical protein YP_001095485.1 KEGG: shm:Shewmr7_3517 hypothetical protein YP_001095486.1 KEGG: sdn:Sden_3283 hypothetical protein YP_001095487.1 PFAM: Class I peptide chain release factor; KEGG: shm:Shewmr7_3519 class I peptide chain release factor YP_001095488.1 KEGG: sdn:Sden_3285 3-dehydroquinate dehydratase, type II; TIGRFAM: 3-dehydroquinate dehydratase, type II; PFAM: dehydroquinase, class II YP_001095489.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxyl carrier protein; PFAM: biotin/lipoyl attachment domain-containing protein; KEGG: plu:plu4074 biotin carboxyl carrier protein of acetyl-CoA carboxylase (BCCP) YP_001095490.1 TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: pmu:PM1091 biotin carboxylase, a subunit YP_001095491.1 PFAM: histidine kinase, HAMP region domain protein; SMART: extracellular solute-binding protein, family 3; metal-dependent phosphohydrolase, HD region; KEGG: vvy:VV1527 hypothetical protein YP_001095492.1 KEGG: sfr:Sfri_0480 hypothetical protein YP_001095493.1 PFAM: phosphoesterase, PA-phosphatase related; KEGG: son:SO4195 PAP2 family protein YP_001095494.1 KEGG: shm:Shewmr7_0408 hypothetical protein YP_001095495.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_001095497.1 PFAM: Arginase/agmatinase/formiminoglutamase; KEGG: she:Shewmr4_3550 arginase/agmatinase/formiminoglutamase YP_001095498.1 TIGRFAM: ubiquinone/menaquinone biosynthesis methyltransferases; PFAM: UbiE/COQ5 methyltransferase; Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_0405 ubiquinone/menaquinone biosynthesis methyltransferases YP_001095499.1 PFAM: protein of unknown function DUF1243; KEGG: she:Shewmr4_3552 protein of unknown function DUF1243 YP_001095500.1 TIGRFAM: 2-polyprenylphenol 6-hydroxylase; PFAM: ABC-1 domain protein; KEGG: shm:Shewmr7_0403 2-polyprenylphenol 6-hydroxylase YP_001095501.1 TIGRFAM: twin-arginine translocation protein, TatA/E family subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: sdn:Sden_0458 twin-arginine translocation protein, TatA/E family YP_001095502.1 TIGRFAM: twin-arginine translocation protein, TatB subunit; PFAM: sec-independent translocation protein mttA/Hcf106; KEGG: shm:Shewmr7_0401 twin-arginine translocation protein, TatB subunit YP_001095503.1 TIGRFAM: Sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; KEGG: sfr:Sfri_0470 sec-independent protein translocase, TatC subunit YP_001095504.1 KEGG: she:Shewmr4_3557 hypothetical protein YP_001095505.1 PFAM: TatD-related deoxyribonuclease; KEGG: shm:Shewmr7_0398 TatD-related deoxyribonuclease YP_001095506.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; Diverse 7TM receptor, extracellular region 2; Diverse 7TM receptor, transmembrane region; KEGG: son:SO4207 GGDEF domain protein YP_001095507.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_001095509.1 catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway YP_001095510.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_001095511.1 PFAM: band 7 protein; KEGG: son:SO4128 SPFH domain/Band 7 family protein YP_001095512.1 PFAM: band 7 protein; KEGG: son:SO4129 SPFH domain/Band 7 family protein YP_001095513.1 PFAM: protein of unknown function DUF107; KEGG: son:SO4130 hypothetical protein YP_001095514.1 KEGG: sfr:Sfri_3402 hypothetical protein YP_001095515.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_001095516.1 PFAM: protein of unknown function DUF465; KEGG: son:SO4134 hypothetical protein YP_001095517.1 PFAM: Orn/DAP/Arg decarboxylase 2; KEGG: shm:Shewmr7_0445 diaminopimelate decarboxylase YP_001095518.1 KEGG: son:SO4138 hypothetical protein YP_001095519.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_0443 MscS mechanosensitive ion channel YP_001095520.1 PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: shm:Shewmr7_3501 radical SAM domain protein YP_001095521.1 KEGG: sfr:Sfri_3497 hypothetical protein YP_001095522.1 PFAM: GCN5-related N-acetyltransferase; KEGG: sfr:Sfri_0501 GCN5-related N-acetyltransferase YP_001095523.1 PFAM: cytochrome c, class I; KEGG: sdn:Sden_1464 cytochrome c, class I YP_001095524.1 PFAM: FMN-binding domain protein; KEGG: ppr:PBPRB0846 hypothetical NosR, regulator of nitric oxide reductase transcription YP_001095525.1 reduces nitrous oxide to nitrogen YP_001095526.1 PFAM: periplasmic copper-binding; SMART: Parallel beta-helix repeat; Carbohydrate-binding and sugar hydrolysis; KEGG: sdn:Sden_2218 periplasmic copper-binding YP_001095527.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: sdn:Sden_2217 ABC transporter-related protein YP_001095528.1 PFAM: ABC-2 type transporter; KEGG: ppr:PBPRB0850 hypothetical nitrous oxide metabolic protein YP_001095529.1 PFAM: NosL family protein; KEGG: ppr:PBPRB0851 hypothetical NosL protein YP_001095530.1 TIGRFAM: drug resistance transporter, EmrB/QacA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: son:SO0525 drug resistance transporter, EmrB/QacA family protein YP_001095531.1 PFAM: secretion protein HlyD family protein; KEGG: shm:Shewmr7_3509 secretion protein HlyD family protein YP_001095532.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0523 transcriptional regulator, LysR family YP_001095533.1 PFAM: protein of unknown function DUF28; KEGG: sfr:Sfri_1086 protein of unknown function DUF28 YP_001095534.1 KEGG: she:Shewmr4_3064 putative lipoprotein YP_001095535.1 PFAM: permease; KEGG: she:Shewmr4_0447 permease YP_001095536.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_001095537.1 involved in de novo purine biosynthesis YP_001095538.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_001095539.1 KEGG: vpa:VP0948 hypothetical protein YP_001095540.1 PFAM: short-chain dehydrogenase/reductase SDR; KR; KEGG: shm:Shewmr7_3588 short-chain dehydrogenase/reductase SDR YP_001095541.1 TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-4 domain protein; KEGG: son:SO0437 sensory box protein YP_001095542.1 KEGG: sfr:Sfri_0487 hypothetical protein YP_001095543.1 KEGG: shm:Shewmr7_0668 hypothetical protein YP_001095544.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_0485 two component transcriptional regulator, winged helix family protein YP_001095545.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sfr:Sfri_0484 periplasmic sensor signal transduction histidine kinase YP_001095547.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_001095548.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_001095549.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_001095550.1 YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate YP_001095551.1 PFAM: peptidase M13, neprilysin; peptidase M13; KEGG: she:Shewmr4_0433 endothelin-converting enzyme 1 YP_001095552.1 PFAM: Patatin; KEGG: she:Shewmr4_0432 patatin YP_001095553.1 KEGG: son:SO0427 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; Two component regulator propeller; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001095554.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_001095555.1 KEGG: shm:Shewmr7_3598 pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; TIGRFAM: pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein YP_001095556.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_001095557.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_001095558.1 involved in regulation of beta-lactamase; putative signaling protein YP_001095559.1 PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; KEGG: sfr:Sfri_3780 N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD YP_001095560.1 KEGG: shm:Shewmr7_3603 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase YP_001095561.1 KEGG: she:Shewmr4_0422 methylation site containing protein YP_001095562.1 PFAM: O-antigen polymerase; KEGG: she:Shewmr4_0421 O-antigen polymerase YP_001095563.1 TIGRFAM: type IV-A pilus assembly ATPase PilB; PFAM: type II secretion system protein E; General secretory system II, protein E domain protein; KEGG: shm:Shewmr7_3605 type IV-A pilus assembly ATPase PilB YP_001095564.1 PFAM: type II secretion system protein; KEGG: she:Shewmr4_0419 type II secretion system protein YP_001095565.1 PFAM: peptidase A24A, prepilin type IV; peptidase A24A domain protein; KEGG: sfr:Sfri_3785 prepilin peptidase YP_001095566.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_001095567.1 PFAM: protein of unknown function DUF1342; KEGG: shm:Shewmr7_3609 protein of unknown function DUF1342 YP_001095568.1 PFAM: protein of unknown function DUF329; KEGG: shm:Shewmr7_3610 protein of unknown function DUF329 YP_001095569.1 TIGRFAM: mutator MutT protein; PFAM: NUDIX hydrolase; KEGG: shm:Shewmr7_3611 mutator MutT protein YP_001095570.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_001095571.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0393 peptidase M23B YP_001095572.1 KEGG: shm:Shewmr7_0392 hypothetical protein YP_001095573.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_001095574.1 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function YP_001095575.1 PFAM: cell division protein FtsA; KEGG: shm:Shewmr7_0389 cell division protein FtsA YP_001095576.1 PFAM: cell division protein FtsQ; Polypeptide-transport-associated domain protein, FtsQ-type; KEGG: son:SO4217 cell division protein FtsQ YP_001095577.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_001095578.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_001095579.1 TIGRFAM: cell division protein FtsW; PFAM: cell cycle protein; KEGG: shm:Shewmr7_0385 cell division protein FtsW YP_001095580.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_001095581.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_001095582.1 TIGRFAM: UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; PFAM: cytoplasmic peptidoglycan synthetase domain protein; cytoplasmic peptidoglycan synthetases domain protein; Mur ligase, middle domain protein; KEGG: shm:Shewmr7_0382 UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl- D-alanyl ligase YP_001095583.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_001095584.1 PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; KEGG: she:Shewmr4_3576 peptidoglycan glycosyltransferase YP_001095585.1 PFAM: cell division protein FtsL; KEGG: she:Shewmr4_3577 cell division protein FtsL YP_001095586.1 TIGRFAM: S-adenosyl-methyltransferase MraW; PFAM: methyltransferase; KEGG: she:Shewmr4_3578 S-adenosyl-methyltransferase MraW YP_001095587.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_001095588.1 PFAM: PepSY-associated TM helix domain protein; KEGG: sdn:Sden_0345 PepSY-associated TM helix YP_001095589.1 PFAM: ferredoxin; KEGG: she:Shewmr4_3581 PepSY-associated TM helix domain protein YP_001095590.1 KEGG: sfr:Sfri_3814 hypothetical protein YP_001095591.1 TIGRFAM: glycerol kinase; PFAM: carbohydrate kinase, FGGY; KEGG: son:SO4230 glycerol kinase YP_001095592.1 KEGG: sdn:Sden_0341 hypothetical protein YP_001095593.1 PFAM: membrane protein involved in aromatic hydrocarbon degradation; KEGG: she:Shewmr4_3584 membrane protein involved in aromatic hydrocarbon degradation YP_001095594.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_001095595.1 dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate YP_001095596.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_001095597.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_001095598.1 KEGG: shm:Shewmr7_0367 tetratricopeptide domain protein YP_001095599.1 KEGG: son:SO4241 ATP-dependent DNA helicase RecQ; TIGRFAM: ATP-dependent DNA helicase, RecQ family; ATP-dependent DNA helicase RecQ; PFAM: helicase domain protein; HRDC domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like YP_001095600.1 TIGRFAM: uncharacterized domain 1 protein; PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_3591 uncharacterized domain 1 protein YP_001095601.1 TIGRFAM: RarD protein, DMT superfamily transporter; PFAM: protein of unknown function DUF6, transmembrane; KEGG: son:SO4243 rarD protein YP_001095602.1 KEGG: shm:Shewmr7_0363 hypothetical protein YP_001095603.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_001095604.1 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif YP_001095605.1 required for 70S ribosome assembly YP_001095606.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_001095607.1 KEGG: sfr:Sfri_3829 phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; PFAM: flavoprotein; DNA/pantothenate metabolism flavoprotein domain protein YP_001095608.1 catalyzes the formation of dUMP from dUTP YP_001095609.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_001095610.1 PFAM: peptidase S9, prolyl oligopeptidase active site domain protein; dienelactone hydrolase; KEGG: son:SO4252 prolyl oligopeptidase family protein YP_001095611.1 involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer YP_001095612.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_001095613.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_001095614.1 PFAM: YicC N-terminal domain protein; domain of unknown function DUF1732; KEGG: she:Shewmr4_3605 hypothetical protein YP_001095615.1 PFAM: helix-turn-helix domain protein; KEGG: shm:Shewmr7_0337 transcriptional regulator, XRE family YP_001095616.1 KEGG: shm:Shewmr7_0338 hypothetical protein YP_001095617.1 PFAM: Paraquat-inducible protein A; KEGG: pha:PSHAa0301 hypothetical protein YP_001095618.1 PFAM: acetyl-CoA hydrolase/transferase; KEGG: sfr:Sfri_0862 acetyl-CoA hydrolase/transferase YP_001095619.1 PFAM: aminoglycoside phosphotransferase; KEGG: shm:Shewmr7_0333 aminoglycoside phosphotransferase YP_001095620.1 KEGG: son:SO0363 hypothetical protein YP_001095621.1 KEGG: sfr:Sfri_0366 hypothetical protein YP_001095622.1 Essential for recycling GMP and indirectly, cGMP YP_001095623.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_001095624.1 KEGG: shm:Shewmr7_0328 (p)ppGpp synthetase I, SpoT/RelA; TIGRFAM: RelA/SpoT family protein; PFAM: amino acid-binding ACT domain protein; TGS domain protein; metal-dependent phosphohydrolase, HD sub domain; RelA/SpoT domain protein; SMART: metal-dependent phosphohydrolase, HD region YP_001095625.1 TIGRFAM: putative endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP; KEGG: sdn:Sden_3436 YjgF-like protein YP_001095626.1 specifically modifies tRNA at position G18 YP_001095627.1 PFAM: AMP-dependent synthetase and ligase; KEGG: son:SO0355 AMP-binding protein YP_001095628.1 TIGRFAM: Na+/Ca+ antiporter, CaCA family; PFAM: sodium/calcium exchanger membrane region; KEGG: shm:Shewmr7_0325 Na+/Ca+ antiporter, CaCA family YP_001095629.1 PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; KEGG: shm:Shewmr7_0324 TPR repeat-containing protein YP_001095630.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, dimerisation and phosphoacceptor region; KEGG: shm:Shewmr7_0323 putative signal transduction histidine kinase YP_001095631.1 PFAM: regulatory protein, LuxR; response regulator receiver; Bacterio-opsin activator, HTH domain protein; Sigma-70, region 4 type 2; KEGG: son:SO0351 DNA-binding response regulator, LuxR family YP_001095632.1 catalyzes branch migration in Holliday junction intermediates YP_001095633.1 KEGG: sfr:Sfri_0355 hypothetical protein YP_001095634.1 KEGG: shm:Shewmr7_3674 hypothetical protein YP_001095635.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: shm:Shewmr7_3675 phospholipid/glycerol acyltransferase YP_001095636.1 KEGG: shm:Shewmr7_3676 acyl carrier protein, putative YP_001095637.1 carries the fatty acid chain in fatty acid biosynthesis YP_001095638.1 KEGG: son:SO4370 hypothetical protein YP_001095639.1 KEGG: shm:Shewmr7_3679 hypothetical protein YP_001095640.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: she:Shewmr4_0346 thioester dehydrase family protein YP_001095641.1 PFAM: glycosyl transferase, family 2; lipid A biosynthesis acyltransferase; KEGG: she:Shewmr4_0345 glycosyl transferase, family 2 YP_001095642.1 PFAM: phenylalanine/histidine ammonia-lyase; KEGG: shm:Shewmr7_3682 histidine ammonia-lyase YP_001095643.1 KEGG: shm:Shewmr7_3683 thioesterase superfamily protein YP_001095644.1 PFAM: outer membrane lipoprotein carrier protein LolA; KEGG: son:SO4376 hypothetical protein YP_001095645.1 KEGG: she:Shewmr4_0341 hypothetical protein YP_001095646.1 PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; tryptophan halogenase; KEGG: shm:Shewmr7_3686 monooxygenase, FAD-binding protein YP_001095647.1 KEGG: sfr:Sfri_0341 hypothetical protein YP_001095648.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001095649.1 PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; KEGG: sfr:Sfri_0339 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ YP_001095650.1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_001095651.1 FabB; beta-ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP YP_001095652.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_0328 GCN5-related N-acetyltransferase YP_001095653.1 PFAM: Rhodanese domain protein; KEGG: son:SO4394 phage shock protein E YP_001095654.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_001095655.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_001095656.1 TIGRFAM: aromatic amino acid transporter; PFAM: aromatic amino acid permease; Amino acid transporter, transmembrane; KEGG: sfr:Sfri_0262 aromatic amino acid transporter YP_001095657.1 PFAM: globin; KEGG: cvi:CV2936 probable bacterial hemoglobin YP_001095658.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_0263 glyoxalase/bleomycin resistance protein/dioxygenase YP_001095659.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: she:Shewmr4_3783 heavy metal efflux pump, CzcA family YP_001095660.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: she:Shewmr4_3782 efflux transporter, RND family, MFP subunit YP_001095661.1 KEGG: she:Shewmr4_3781 copper-transporting ATPase domain protein YP_001095662.1 KEGG: son:SOA0156 hypothetical protein YP_001095663.1 KEGG: sfr:Sfri_0591 hypothetical protein YP_001095665.1 PFAM: NapC/NirT cytochrome c domain protein; KEGG: son:SO4591 tetraheme cytochrome c YP_001095666.1 TIGRFAM: thioesterase domain, putative; KEGG: she:Shewmr4_0320 thioesterase domain, putative YP_001095667.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_001095668.1 KEGG: son:SO4399 hypothetical protein YP_001095669.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO4400 proline iminopeptidase, putative YP_001095670.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_001095671.1 KEGG: shm:Shewmr7_3709 hypothetical protein YP_001095672.1 KEGG: shm:Shewmr7_3710 hypothetical protein YP_001095674.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: sfr:Sfri_0773 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001095675.1 PFAM: helix-turn-helix- domain containing protein, AraC type; AraC protein, arabinose-binding/dimerisation; KEGG: hch:HCH_02929 AraC-type DNA-binding domain-containing protein YP_001095676.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: vpa:VPA1016 multidrug resistance protein D YP_001095677.1 PFAM: transposase, IS111A/IS1328/IS1533; transposase IS116/IS110/IS902 family protein; KEGG: she:Shewmr4_3024 transposase IS116/IS110/IS902 family protein YP_001095678.1 TIGRFAM: small GTP-binding protein; GTP-binding protein TypA; PFAM: elongation factor G domain protein; protein synthesis factor, GTP-binding; elongation factor Tu, domain 2 protein; KEGG: shm:Shewmr7_3718 GTP-binding protein TypA YP_001095679.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_001095680.1 KEGG: shm:Shewmr7_0880 hypothetical protein YP_001095681.1 PFAM: aminotransferase, class V; KEGG: shm:Shewmr7_3724 aminotransferase, class V YP_001095682.1 KEGG: she:Shewmr4_0294 hypothetical protein YP_001095683.1 PFAM: regulatory protein, AsnC/Lrp family; Helix-turn-helix, type 11 domain protein; KEGG: pha:PSHAa0053 transcriptional regulator YP_001095684.1 KEGG: shm:Shewmr7_3762 hypothetical protein YP_001095685.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: shm:Shewmr7_3763 signal transduction histidine kinase, nitrogen specific, NtrB YP_001095686.1 KEGG: shm:Shewmr7_3764 nitrogen metabolism transcriptional regulator, NtrC, fis family; TIGRFAM: nitrogen regulation protein NR(I); PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase YP_001095687.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO0843 transcriptional regulator, LysR family YP_001095688.1 KEGG: shm:Shewmr7_2645 hypothetical protein YP_001095689.1 KEGG: shm:Shewmr7_2646 hypothetical protein YP_001095690.1 PFAM: acriflavin resistance protein; KEGG: sdn:Sden_2206 acriflavin resistance protein YP_001095691.1 TIGRFAM: efflux transporter, RND family, MFP subunit; KEGG: sdn:Sden_2205 membrane-fusion protein YP_001095692.1 PFAM: regulatory protein, TetR; KEGG: sdn:Sden_2204 regulatory protein, TetR YP_001095693.1 TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: shm:Shewmr7_3767 cation diffusion facilitator family transporter YP_001095694.1 PFAM: protein of unknown function, Spy-related; KEGG: she:Shewmr4_0253 protein of unknown function, Spy-related YP_001095695.1 PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sfr:Sfri_0311 two component transcriptional regulator, winged helix family protein YP_001095696.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: son:SO4478 sensor protein CpxA YP_001095697.1 PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: she:Shewmr4_2154 alcohol dehydrogenase, zinc-binding domain protein YP_001095698.1 PFAM: sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; GAF domain protein; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3771 GAF modulated sigma54 specific transcriptional regulator, fis family YP_001095699.1 PFAM: aldehyde dehydrogenase; KEGG: shm:Shewmr7_3772 aldehyde dehydrogenase (NAD(+)) YP_001095701.1 KEGG: rme:Rmet_2216 cysteine dioxygenase type I YP_001095702.1 TIGRFAM: RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase (SpoU); KEGG: she:Shewmr4_3736 RNA methyltransferase, TrmH family, group 2 YP_001095703.1 KEGG: she:Shewmr4_3739 hypothetical protein YP_001095704.1 KEGG: dar:Daro_0041 hypothetical protein YP_001095705.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3814 peptidase M16 domain protein YP_001095706.1 PFAM: peptidase M16 domain protein; KEGG: shm:Shewmr7_3815 peptidase M16 domain protein YP_001095707.1 KEGG: pha:PSHAa0016 hypothetical protein YP_001095708.1 PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_3819 methyltransferase type 11 YP_001095709.1 KEGG: she:Shewmr4_3747 hypothetical protein YP_001095710.1 KEGG: son:SO4552 sensory box protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; PAS fold domain protein; SMART: PAS domain containing protein YP_001095711.1 PFAM: DTW domain containing protein; KEGG: sfr:Sfri_0299 DTW domain containing protein YP_001095712.1 KEGG: sfr:Sfri_3123 hypothetical protein YP_001095713.1 TIGRFAM: drug resistance transporter, Bcr/CflA subfamily; PFAM: major facilitator superfamily MFS_1; KEGG: she:Shewmr4_3750 drug resistance transporter, Bcr/CflA subfamily YP_001095714.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: son:SO4556 transcriptional regulator, LysR family YP_001095715.1 KEGG: son:SO4558 hypothetical protein YP_001095716.1 KEGG: ccr:CC3273 hypothetical protein YP_001095717.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: son:SO4559 hypothetical protein YP_001095718.1 KEGG: she:Shewmr4_3755 hypothetical protein YP_001095719.1 KEGG: shm:Shewmr7_3829 hypothetical protein YP_001095720.1 PFAM: protein of unknown function DUF1332; KEGG: she:Shewmr4_3757 protein of unknown function DUF1332 YP_001095721.1 PFAM: Methyltransferase type 11; KEGG: cps:CPS_0687 hypothetical protein YP_001095722.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_001095723.1 PFAM: regulatory protein, AsnC/Lrp family; regulatory protein, ArsR; KEGG: shm:Shewmr7_3834 transcriptional regulator, AsnC family YP_001095724.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_001095725.1 PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3841 alpha/beta hydrolase fold YP_001095726.1 catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate YP_001095727.1 TIGRFAM: O-succinylbenzoate-CoA ligase; PFAM: AMP-dependent synthetase and ligase; KEGG: she:Shewmr4_3770 O-succinylbenzoate-CoA ligase YP_001095728.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_001095729.1 PFAM: protein of unknown function DUF214; KEGG: son:SO4584 cell division ABC transporter, permease protein FtsX YP_001095730.1 KEGG: shm:Shewmr7_3846 cell division ATP-binding protein FtsE; TIGRFAM: cell division ATP-binding protein FtsE; PFAM: ABC transporter-related protein; SMART: AAA ATPase YP_001095731.1 KEGG: shm:Shewmr7_3847 signal recognition particle-docking protein FtsY; TIGRFAM: signal recognition particle-docking protein FtsY; PFAM: GTP-binding signal recognition particle SRP54, G- domain; GTP-binding signal recognition particle SRP54, helical bundle; SMART: AAA ATPase YP_001095732.1 TIGRFAM: putative methyltransferase; PFAM: conserved hypothetical protein 95; KEGG: she:Shewmr4_3775 putative methyltransferase YP_001095733.1 PFAM: protein of unknown function DUF1145; KEGG: shm:Shewmr7_3849 protein of unknown function DUF1145 YP_001095734.1 PFAM: type II secretion system protein N; KEGG: shm:Shewmr7_0161 type II secretion system protein N YP_001095735.1 PFAM: General secretion pathway M protein; KEGG: shm:Shewmr7_0160 general secretion pathway M protein YP_001095736.1 TIGRFAM: general secretion pathway protein L; PFAM: General secretion pathway L; KEGG: shm:Shewmr7_0159 general secretion pathway protein L YP_001095737.1 PFAM: General secretion pathway protein K; KEGG: shm:Shewmr7_0158 general secretion pathway protein K YP_001095738.1 TIGRFAM: general secretion pathway protein J; KEGG: she:Shewmr4_0162 general secretion pathway protein J YP_001095739.1 TIGRFAM: general secretion pathway protein I; PFAM: type II secretion system protein I/J; KEGG: shm:Shewmr7_0156 general secretion pathway protein I YP_001095740.1 TIGRFAM: general secretion pathway protein H; KEGG: son:SO0170 general secretion pathway protein H YP_001095741.1 TIGRFAM: general secretion pathway protein G; PFAM: type II secretion system protein G; KEGG: shm:Shewmr7_0154 general secretion pathway protein G YP_001095742.1 TIGRFAM: general secretion pathway protein F; PFAM: type II secretion system protein; KEGG: sfr:Sfri_0107 general secretion pathway protein F YP_001095743.1 KEGG: shm:Shewmr7_0152 general secretory pathway protein E; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; SMART: AAA ATPase YP_001095744.1 TIGRFAM: general secretion pathway protein D; PFAM: type II and III secretion system protein; NolW domain protein; KEGG: shm:Shewmr7_0151 general secretion pathway protein D YP_001095745.1 TIGRFAM: general secretion pathway protein C; KEGG: she:Shewmr4_0155 general secretion pathway protein C YP_001095746.1 PFAM: RNA-binding S4 domain protein; KEGG: shm:Shewmr7_0149 RNA-binding S4 domain protein YP_001095747.1 becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers YP_001095748.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_001095749.1 KEGG: shm:Shewmr7_0144 hypothetical protein YP_001095750.1 PFAM: sodium:dicarboxylate symporter; KEGG: she:Shewmr4_0147 sodium:dicarboxylate symporter YP_001095751.1 KEGG: sfr:Sfri_3409 hypothetical protein YP_001095752.1 PFAM: helix-turn-helix domain protein; KEGG: ccr:CC2232 transcriptional regulator, Cro/CI family YP_001095753.1 PFAM: MgtC/SapB transporter; KEGG: ilo:IL2442 uncharacterized conserved membrane protein, SapB/MtgC family YP_001095754.1 KEGG: she:Shewmr4_3805 competence protein ComF YP_001095755.1 TIGRFAM: bioH protein; PFAM: alpha/beta hydrolase fold; KEGG: shm:Shewmr7_3882 BioH protein YP_001095756.1 KEGG: she:Shewmr4_3807 hypothetical protein YP_001095757.1 PFAM: sulfatase; KEGG: son:SO4628 sulfatase YP_001095759.1 PFAM: RNA binding S1 domain protein; SMART: Resolvase, RNase H domain protein fold; KEGG: son:SO4629 hypothetical protein YP_001095760.1 PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: sdn:Sden_1376 thiamine pyrophosphate enzyme-like TPP binding region YP_001095761.1 TIGRFAM: transcription elongation factor GreB; PFAM: transcription elongation factor GreA/GreB domain protein; KEGG: she:Shewmr4_3810 transcription elongation factor GreB YP_001095762.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_001095763.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_001095764.1 PFAM: histidine kinase, HAMP region domain protein; chemotaxis sensory transducer; KEGG: shm:Shewmr7_3904 methyl-accepting chemotaxis sensory transducer YP_001095766.1 PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: shm:Shewmr7_3905 redoxin domain protein YP_001095767.1 KEGG: sfr:Sfri_0214 hypothetical protein YP_001095768.1 KEGG: rso:RS01914 hypothetical protein YP_001095772.1 PFAM: protein of unknown function DUF548; KEGG: shm:Shewmr7_3921 protein of unknown function DUF548 YP_001095773.1 PFAM: protein of unknown function DUF519; KEGG: son:SO4659 hypothetical protein YP_001095774.1 KEGG: sdn:Sden_1152 hypothetical protein YP_001095775.1 PFAM: Lytic transglycosylase, catalytic; KEGG: shm:Shewmr7_3923 lytic transglycosylase, catalytic YP_001095776.1 KEGG: shm:Shewmr7_3924 hypothetical protein YP_001095777.1 PFAM: LemA family protein; KEGG: son:SO4662 lemA protein YP_001095779.1 PFAM: AbgT putative transporter; KEGG: she:Shewmr4_3833 AbgT putative transporter YP_001095780.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: sde:Sde_2875 transcriptional regulator, LysR family YP_001095781.1 PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: sfr:Sfri_2561 glyoxalase/bleomycin resistance protein/dioxygenase YP_001095782.1 PFAM: peptidase M3A and M3B, thimet/oligopeptidase F; KEGG: shm:Shewmr7_3935 oligopeptidase A YP_001095783.1 KEGG: son:SO4700 hypothetical protein YP_001095784.1 KEGG: son:SO4701 hypothetical protein YP_001095785.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_001095789.1 TIGRFAM: alpha-L-glutamate ligases, RimK family; PFAM: protein of unknown function DUF201; RimK domain protein ATP-grasp; KEGG: vpa:VPA0173 ribosomal protein S6 modification protein YP_001095790.1 PFAM: Succinylglutamate desuccinylase/aspartoacylase; KEGG: sde:Sde_2033 hypothetical protein YP_001095791.1 PFAM: protein of unknown function DUF785; KEGG: sde:Sde_2034 transglutaminase-like YP_001095792.1 PFAM: MgtE integral membrane region; KEGG: vpa:VPA0778 putataive Mg transporter MgtE YP_001095793.1 PFAM: conserved hypothetical protein 698; KEGG: son:SO4708 hypothetical protein YP_001095794.1 PFAM: ThiJ/PfpI domain protein; KEGG: sil:SPOA0286 ThiJ/PfpI family protein YP_001095795.1 PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: shm:Shewmr7_3954 metal dependent phosphohydrolase YP_001095796.1 KEGG: shm:Shewmr7_3955 hypothetical protein YP_001095797.1 KEGG: shm:Shewmr7_3956 hypothetical protein YP_001095798.1 KEGG: shm:Shewmr7_3957 hypothetical protein YP_001095799.1 PFAM: cobalt transport protein; KEGG: she:Shewmr4_3865 cobalt transport protein YP_001095800.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4712 ABC transporter, ATP-binding protein, putative YP_001095801.1 PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: shm:Shewmr7_3960 TonB-dependent receptor, plug YP_001095802.1 TIGRFAM: isochorismate synthases; PFAM: Anthranilate synthase component I and chorismate binding protein; KEGG: sfr:Sfri_3913 isochorismate synthases YP_001095803.1 KEGG: son:SO4714 hypothetical protein YP_001095804.1 TIGRFAM: conserved hypothetical integral membrane protein; PFAM: protein of unknown function DUF165; KEGG: son:SO4715 hypothetical protein YP_001095805.1 PFAM: GCN5-related N-acetyltransferase; KEGG: she:Shewmr4_3871 acetyltransferase, GNAT family YP_001095806.1 PFAM: ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: she:Shewmr4_3872 periplasmic sensor signal transduction histidine kinase YP_001095807.1 PFAM: response regulator receiver; sigma-54 factor, interaction domain-containing protein; helix-turn-helix, Fis-type; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: shm:Shewmr7_3966 two component, sigma54 specific, transcriptional regulator, fis family YP_001095808.1 KEGG: she:Shewmr4_3874 extracellular solute-binding protein, family 1 YP_001095809.1 PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: shm:Shewmr7_3968 binding-protein-dependent transport systems inner membrane component YP_001095810.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO4721 ABC transporter, ATP-binding protein YP_001095811.1 TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein A; KEGG: son:SO4722 molybdopterin-guanine dinucleotide biosynthesis protein YP_001095812.1 TIGRFAM: molybdenum cofactor synthesis domain; molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin binding domain; molybdopterin-guanine dinucleotide biosynthesis MobB region; MoeA domain protein, domain I and II; MoeA domain protein, domain IV; KEGG: she:Shewmr4_3878 molybdopterin-guanine dinucleotide biosynthesis protein B YP_001095813.1 together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z YP_001095814.1 KEGG: shm:Shewmr7_3973 hypothetical protein YP_001095815.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_001095816.1 KEGG: sfr:Sfri_3925 hypothetical protein YP_001095817.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_001095818.1 KEGG: sfr:Sfri_3928 ADP-heptose--lipooligosaccharide heptosyltransferase III YP_001095819.1 TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid dehydrogenase/isomerase; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: sfr:Sfri_3929 ADP-L-glycero-D-manno-heptose-6-epimerase YP_001095820.1 TIGRFAM: cytidyltransferase-related domain protein; PFAM: cytidylyltransferase; KEGG: sfr:Sfri_3930 cytidyltransferase-related domain protein YP_001095821.1 PFAM: CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase; KEGG: sfr:Sfri_3931 CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase YP_001095822.1 PFAM: glycosyl transferase, family 9; KEGG: sfr:Sfri_3932 ADP-heptose:LPS heptosyltransferase-like protein YP_001095823.1 KEGG: sfr:Sfri_3933 glycosyl transferase, family 8 YP_001095824.1 PFAM: glycosyl transferase, family 2; KEGG: vpa:VP0192 hypothetical protein YP_001095825.1 PFAM: glycosyl transferase, group 1; KEGG: she:Shewmr4_3895 glycosyl transferase, group 1 YP_001095826.1 KEGG: pha:PSHAa2321 hypothetical protein YP_001095827.1 PFAM: glycosyl transferase, family 9; KEGG: shm:Shewmr7_3988 glycosyl transferase, family 9 YP_001095828.1 KEGG: aeh:Mlg_2320 dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase related YP_001095829.1 TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; polysaccharide biosynthesis protein CapD; dTDP-4-dehydrorhamnose reductase; Male sterility C-terminal domain; KEGG: pfo:Pfl_0701 dTDP-glucose 4,6-dehydratase YP_001095830.1 PFAM: NAD-dependent epimerase/dehydratase; dTDP-4-dehydrorhamnose reductase; KEGG: sdn:Sden_2549 dTDP-4-dehydrorhamnose reductase YP_001095831.1 catalyzes the phosphorylation of 3-deoxy-D-manno-octulosonic acid at the 4-OH position YP_001095832.1 PFAM: Three-deoxy-D-manno-octulosonic-acid transferase domain protein; KEGG: she:Shewmr4_3898 three-deoxy-D-manno-octulosonic-acid transferase domain protein YP_001095833.1 PFAM: regulatory protein, TetR; KEGG: sdn:Sden_3614 regulatory protein, TetR YP_001095834.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_001095835.1 converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism YP_001095836.1 PFAM: Rhodanese domain protein; KEGG: sdn:Sden_3617 rhodanese-like protein YP_001095837.1 PFAM: Rhomboid family protein; KEGG: son:SO4671 glpG protein YP_001095838.1 PFAM: ThiJ/PfpI domain protein; KEGG: son:SO4670 enhancing lycopene biosynthesis protein YP_001095839.1 KEGG: shm:Shewmr7_3997 DNA polymerase I; TIGRFAM: DNA polymerase I; PFAM: DNA-directed DNA polymerase; 5'-3' exonuclease; 3'-5' exonuclease; SMART: Helix-hairpin-helix domain protein, class 2 YP_001095840.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_001095841.1 PFAM: cytochrome c, class I; KEGG: son:SO4666 cytochrome c YP_001095842.1 KEGG: son:SO4727 hypothetical protein YP_001095843.1 KEGG: son:SO4728 hypothetical protein YP_001095844.1 KEGG: she:Shewmr4_3910 hypothetical protein YP_001095845.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_001095846.1 catalyzes the formation of inosine from adenosine YP_001095847.1 PFAM: protein of unknown function DUF885; KEGG: son:SO4732 hypothetical protein YP_001095848.1 PFAM: alpha/beta hydrolase fold; KEGG: son:SO4733 lysophospholipase L2 YP_001095849.1 KEGG: sfr:Sfri_0038 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; histidine kinase, HAMP region domain protein; PAS fold-3 domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein YP_001095850.1 KEGG: she:Shewmr4_0039 carbonic anhydrase, family 3 YP_001095851.1 PFAM: protein of unknown function DUF1488; KEGG: vpa:VP3032 hypothetical protein YP_001095852.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_001095853.1 PFAM: globin; KEGG: sdn:Sden_0031 globin YP_001095854.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_001095855.1 TIGRFAM: Sua5/YciO/YrdC/YwlC family protein; PFAM: SUA5/yciO/yrdC, N-terminal domain; KEGG: son:SO0037 Sua5/YciO/YrdC/YwlC family protein YP_001095856.1 PFAM: DNA topoisomerase, type IA, zn finger domain protein; KEGG: shm:Shewmr7_0031 DNA topoisomerase, type IA, zn finger domain protein YP_001095857.1 PFAM: Peptidase M9A, collagenase C-terminal domain protein; KEGG: cps:CPS_2237 microbial collagenase YP_001095858.1 PFAM: protein of unknown function DUF494; KEGG: sfr:Sfri_0027 protein of unknown function DUF494 YP_001095859.1 TIGRFAM: DNA protecting protein DprA; PFAM: SMF family protein; KEGG: son:SO0034 DNA processing protein DprA, putative YP_001095860.1 PFAM: Peptidoglycan-binding LysM; KEGG: son:SO0033 LysM domain protein YP_001095861.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_001095862.1 TIGRFAM: methionyl-tRNA formyltransferase; PFAM: formyl transferase domain protein; KEGG: sfr:Sfri_0023 methionyl-tRNA formyltransferase YP_001095863.1 TIGRFAM: sun protein; PFAM: Fmu (Sun) domain protein; NusB/RsmB/TIM44; KEGG: she:Shewmr4_0027 sun protein YP_001095864.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_001095865.1 TIGRFAM: potassium uptake protein, TrkH family; PFAM: cation transporter; KEGG: shm:Shewmr7_0023 potassium uptake protein, TrkH family YP_001095866.1 PFAM: protein of unknown function DUF890; KEGG: she:Shewmr4_0128 protein of unknown function DUF890 YP_001095867.1 PFAM: flagellar basal body-associated protein FliL; KEGG: sfr:Sfri_0049 flagellar basal body-associated protein FliL YP_001095868.1 PFAM: Chorismate lyase; KEGG: son:SO0131 putative chorismate--pyruvate lyase YP_001095869.1 PFAM: PKD domain containing protein; peptidase M6, immune inhibitor A; KEGG: sfr:Sfri_0047 peptidase M6, immune inhibitor A YP_001095870.1 PFAM: glycoside hydrolase, family 37; KEGG: cpr:CPR_0360 cell wall surface anchor family protein YP_001095871.1 PFAM: multiple antibiotic resistance (MarC)-related proteins; KEGG: son:SO0129 conserved hypothetical protein TIGR00427 YP_001095872.1 KEGG: she:Shewmr4_0122 hypothetical protein YP_001095873.1 PFAM: protein of unknown function DUF833; KEGG: she:Shewmr4_0121 protein of unknown function DUF833 YP_001095874.1 KEGG: shm:Shewmr7_0115 hypothetical protein YP_001095875.1 PFAM: phospholipid/glycerol acyltransferase; KEGG: she:Shewmr4_0119 phospholipid/glycerol acyltransferase YP_001095876.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: shm:Shewmr7_0113 lysine exporter protein (LysE/YggA) YP_001095877.1 PFAM: MscS Mechanosensitive ion channel; KEGG: shm:Shewmr7_0112 MscS mechanosensitive ion channel YP_001095878.1 KEGG: son:SO0120 hypothetical protein YP_001095879.1 KEGG: sfr:Sfri_3611 hypothetical protein YP_001095880.1 PFAM: thioesterase superfamily protein; KEGG: sfr:Sfri_1838 thioesterase superfamily protein YP_001095881.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_001095882.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_001095883.1 TIGRFAM: histidine utilization repressor; PFAM: regulatory protein GntR, HTH; UbiC transcription regulator-associated domain protein; KEGG: she:Shewmr4_0098 transcriptional regulator, histidine utilization repressor, GntR family YP_001095884.1 catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway YP_001095885.1 PFAM: KAP P-loop domain protein; KEGG: sdn:Sden_3526 kap P-loop YP_001095886.1 KEGG: mag:amb2065 hypothetical protein YP_001095888.1 PFAM: regulatory protein, LuxR; KEGG: she:Shewmr4_3855 transcriptional regulator, LuxR family YP_001095889.1 KEGG: shm:Shewmr7_3949 hypothetical protein YP_001095890.1 KEGG: shm:Shewmr7_3950 hypothetical protein YP_001095891.1 TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_3951 heavy metal efflux pump, CzcA family YP_001095892.1 KEGG: shm:Shewmr7_3952 hypothetical protein YP_001095893.1 KEGG: she:Shewmr4_0541 hypothetical protein YP_001095894.1 KEGG: sfr:Sfri_3965 hypothetical protein YP_001095895.1 PFAM: Sel1 domain protein repeat-containing protein; KEGG: sfr:Sfri_3249 Sel1 domain protein repeat-containing protein YP_001095896.1 TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; 2,3-diketo-5-methylthio-1-phosphopentane phosphatase; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: son:SO0084 HAD-superfamily hydrolase, subfamily IA, variant 1 family protein YP_001095897.1 PFAM: thioesterase superfamily protein; KEGG: she:Shewmr4_0084 thioesterase superfamily protein YP_001095898.1 KEGG: vfi:VFA0508 hypothetical protein YP_001095899.1 KEGG: she:Shewmr4_0083 hypothetical protein YP_001095900.1 PFAM: thioesterase superfamily protein; KEGG: sdn:Sden_0073 thioesterase superfamily YP_001095901.1 PFAM: AMP-dependent synthetase and ligase; KEGG: shm:Shewmr7_0076 AMP-dependent synthetase and ligase YP_001095902.1 KEGG: son:SO0074 hypothetical protein YP_001095903.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: shm:Shewmr7_0074 ABC transporter-related protein YP_001095904.1 PFAM: regulatory protein GntR, HTH; KEGG: sfr:Sfri_3976 transcriptional regulator, GntR family protein YP_001095905.1 PFAM: alpha/beta hydrolase fold; TAP domain protein; KEGG: son:SO0071 hydrolase, alpha/beta hydrolase fold family YP_001095906.1 PFAM: ABC transporter-related protein; SMART: AAA ATPase; KEGG: son:SO0070 ATP-binding transport protein NatA YP_001095907.1 PFAM: ABC-2 type transporter; KEGG: sfr:Sfri_3979 ABC-2 type transporter YP_001095908.1 KEGG: sfr:Sfri_3980 hypothetical protein YP_001095910.1 PFAM: helix-turn-helix- domain containing protein, AraC type; ThiJ/PfpI domain protein; KEGG: shm:Shewmr7_0068 transcriptional regulator, AraC family YP_001095911.1 KEGG: shm:Shewmr7_0067 hypothetical protein YP_001095912.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_001095913.1 TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; KEGG: hch:HCH_00809 signal transduction histidine kinase YP_001095914.1 KEGG: sde:Sde_0403 ABC-type nitrate/sulfonate/bicarbonate transport system protein YP_001095915.1 TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; response regulator receiver; KEGG: tdn:Tmden_0218 diguanylate cyclase (GGDEF domain) YP_001095918.1 KEGG: cps:CPS_0419 hypothetical protein YP_001095920.1 PFAM: transmembrane pair domain protein; KEGG: par:Psyc_0621 hypothetical protein YP_001095921.1 TIGRFAM: transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: acriflavin resistance protein; KEGG: vpa:VPA0471 putative multidrug efflux membrane fusion protein YP_001095922.1 TIGRFAM: efflux transporter, RND family, MFP subunit; PFAM: secretion protein HlyD family protein; KEGG: vpa:VPA1191 putative multidrug efflux membrane fusion protein YP_001095923.1 PFAM: regulatory protein, LysR; LysR, substrate-binding; KEGG: rme:Rmet_0510 transcriptional regulator, LysR family YP_001095924.1 KEGG: ppr:PBPRB0103 hypothetical protein YP_001095925.1 KEGG: nar:Saro_2604 major facilitator superfamily MFS_1 YP_001095926.1 PFAM: peptidase S41; KEGG: bth:BT3291 hypothetical protein YP_001095927.1 PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: she:Shewmr4_0049 HI0933 family protein YP_001095928.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_001095929.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_001095930.1 PFAM: Rhodanese domain protein; KEGG: sfr:Sfri_4020 rhodanese domain protein YP_001095931.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_001095932.1 PFAM: peptidase M23B; KEGG: shm:Shewmr7_0042 peptidase M23B YP_001095933.1 KEGG: she:Shewmr4_0043 carboxyl-terminal protease; TIGRFAM: carboxyl-terminal protease; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41 YP_001095934.1 PFAM: protein of unknown function DUF610, YibQ; KEGG: son:SO0046 hypothetical protein YP_001095935.1 TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074; KEGG: she:Shewmr4_0041 transcriptional regulator, BadM/Rrf2 family YP_001095936.1 PFAM: protein of unknown function UPF0153; KEGG: sdn:Sden_3703 protein of unknown function UPF0153 YP_001095937.1 PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; KEGG: she:Shewmr4_3916 4Fe-4S ferredoxin, iron-sulfur binding domain protein YP_001095938.1 KEGG: sfr:Sfri_4029 hypothetical protein YP_001095939.1 catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA YP_001095940.1 KEGG: son:SO4740 hypothetical protein YP_001095941.1 KEGG: shm:Shewmr7_0816 OmpA domain protein transmembrane region-containing protein YP_001095942.1 KEGG: sfr:Sfri_0213 likely secreted protein containing plastocyanin domain YP_001095943.1 TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; copper-translocating P-type ATPase; heavy metal translocating P-type ATPase; PFAM: Haloacid dehalogenase domain protein hydrolase; Heavy metal transport/detoxification protein; E1-E2 ATPase-associated domain protein; KEGG: sfr:Sfri_0212 copper-translocating P-type ATPase YP_001095944.1 PFAM: regulatory protein, MerR; KEGG: sfr:Sfri_0211 transcriptional regulator, MerR family protein YP_001095946.1 KEGG: she:Shewmr4_2521 hypothetical protein YP_001095947.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: she:Shewmr4_2522 AAA ATPase, central domain protein YP_001095948.1 PFAM: helix-turn-helix domain protein YP_001095949.1 KEGG: ilo:IL2609 transposon Tn7 transposition transposition regulatory protein TnsE YP_001095950.1 KEGG: ssn:SSO_3894 transposition protein YP_001095951.1 KEGG: ilo:IL2611 transposon Tn7 transposition protein TnsC YP_001095952.1 KEGG: ilo:IL2612 transposon Tn7 transposition protein TnsB YP_001095953.1 KEGG: ilo:IL2613 transposon Tn7 transposition protein TnsA YP_001095954.1 PFAM: transposase IS3/IS911 family protein; KEGG: vch:VCA0792 transposase OrfAB, subunit A YP_001095955.1 PFAM: Integrase, catalytic region; KEGG: vch:VCA0791 transposase OrfAB, subunit B YP_001095956.1 KEGG: spt:SPA1006 putative hydrolase YP_001095957.1 KEGG: ppr:PBPRA1825 hypothetical ISPpu15, transposase Orf2 YP_001095958.1 PFAM: IS66 Orf2 family protein; KEGG: ppr:PBPRA1824 hypothetical protein YP_001095959.1 KEGG: vvy:VV2228 hypothetical protein YP_001095960.1 PFAM: transposase, IS4 family protein; KEGG: vch:VCA0472 IS5 transposase YP_001095961.1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source YP_001095962.1 PFAM: regulatory protein, DeoR; Helix-turn-helix, type 11 domain protein; KEGG: shm:Shewmr7_4013 transcriptional regulator, DeoR family YP_001095963.1 TIGRFAM: TonB-dependent siderophore receptor; PFAM: TonB-dependent receptor; TonB-dependent receptor, plug; KEGG: she:Shewmr4_3922 TonB-dependent siderophore receptor YP_001095964.1 KEGG: sfr:Sfri_4043 UDP-N-acetylglucosamine pyrophosphorylase; TIGRFAM: UDP-N-acetylglucosamine pyrophosphorylase; PFAM: transferase hexapeptide repeat containing protein; Nucleotidyl transferase YP_001095965.1 PFAM: DsrE family protein; KEGG: ppr:PBPRB1553 putative uncharacterized protein involved in oxidation of intracellular sulfur YP_001095966.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_001095967.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_001095968.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_001095969.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_001095970.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_001095971.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_001095972.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_001095973.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_001095974.1 PFAM: ATP synthase I chain; KEGG: son:SO4754 ATP synthase protein I YP_001095975.1 TIGRFAM: parB-like partition proteins; PFAM: ParB domain protein nuclease; KEGG: shm:Shewmr7_4025 ParB-like partition proteins YP_001095976.1 PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: son:SO4756 ParA family protein YP_001095977.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_001095978.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_001095979.1 An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group YP_001095980.1 KEGG: mes:Meso_3002 ubiquinone biosynthesis O-methyltransferase; TIGRFAM: ubiquinone biosynthesis O-methyltransferase; PFAM: Methyltransferase type 11; Methyltransferase type 12 YP_001095981.1 PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: ppr:PBPRB1417 hypothetical inosine-uridine preferring nucleoside hydrolase YP_001095982.1 PFAM: Lysine exporter protein (LYSE/YGGA); KEGG: sfr:Sfri_3118 lysine exporter protein (LysE/YggA) YP_001095983.1 KEGG: sfr:Sfri_3844 hypothetical protein YP_001095984.1 PFAM: Resolvase, N-terminal domain; Resolvase helix-turn-helix domain protein; KEGG: rha:RHA1_ro03159 resolvase YP_001095985.1 PFAM: AAA ATPase, central domain protein; SMART: AAA ATPase; KEGG: atc:AGR_pTi_158 ATPase YP_001095986.1 KEGG: rha:RHA1_ro11076 hypothetical protein YP_001095987.1 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE YP_001095988.1 PFAM: 60 kDa inner membrane insertion protein; KEGG: shm:Shewmr7_4032 60 kDa inner membrane insertion protein YP_001095989.1 PFAM: protein of unknown function DUF37; KEGG: sdn:Sden_3776 protein of unknown function DUF37 YP_001095990.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_001095991.1 in Escherichia coli transcription of this gene is enhanced by polyamines