-- dump date 20111121_014600 -- class Genbank::CDS -- table cds_note -- id note YP_004412447.1 COGs: COG0593 ATPase involved in DNA replication initiation; InterPro IPR003593:IPR013317:IPR001957:IPR013159; KEGG: tjr:TherJR_0001 chromosomal replication initiator protein DnaA; PFAM: Chromosomal replication control, initiator (DnaA)/regulator (Hda); Chromosomal replication initiator, DnaA C-terminal; SMART: Chromosomal replication initiator, DnaA C-terminal; ATPase, AAA+ type, core; SPTR: Chromosomal replication initiator protein dnaA; TIGRFAM: Chromosomal replication control, initiator DnaA; IMG reference gene:2504585450; PFAM: domain; Bacterial dnaA protein; TIGRFAM: chromosomal replication initiator protein DnaA YP_004412448.1 IMG reference gene:2504585451 YP_004412449.1 COGs: COG0592 DNA polymerase sliding clamp subunit (PCNA homolog); InterPro IPR022635:IPR022634:IPR022637:IPR001001; KEGG: vpr:Vpar_0002 DNA polymerase III, beta subunit; PFAM: DNA polymerase III, beta chain, N-terminal; DNA polymerase III, beta chain, C-terminal; DNA polymerase III, beta chain, central; PRIAM: DNA-directed DNA polymerase; SMART: DNA polymerase III, beta chain; SPTR: DNA polymerase III, beta subunit; TIGRFAM: DNA polymerase III, beta chain; IMG reference gene:2504585452; PFAM: DNA polymerase III beta subunit, C-terminal domain; DNA polymerase III beta subunit, N-terminal domain; DNA polymerase III beta subunit, central domain; TIGRFAM: DNA polymerase III, beta subunit YP_004412450.1 COGs: COG1195 Recombinational DNA repair ATPase (RecF pathway); InterPro IPR001238:IPR003395; KEGG: aar:Acear_0004 DNA replication and repair protein RecF; PFAM: RecF/RecN/SMC; SPTR: DNA replication and repair protein recF; TIGRFAM: DNA-binding, RecF; IMG reference gene:2504585453; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: recF protein YP_004412451.1 InterPro IPR007922; KEGG: nth:Nther_0005 hypothetical protein; PFAM: Protein of unknown function DUF721/UPF0232; SPTR: Putative uncharacterized protein; IMG reference gene:2504585454; PFAM: Protein of unknown function (DUF721) YP_004412452.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585455 YP_004412453.1 COGs: COG0187 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) B subunit; InterProIPR001241:IPR003594:IPR006171:IPR011557:IPR 013506:IPR002288; KEGG: afn:Acfer_0008 DNA gyrase, B subunit; PFAM: DNA topoisomerase, type IIA, subunit B, domain 2; ATPase-like, ATP-binding domain; Toprim domain; DNA topoisomerase, type IIA, subunit B, C-terminal; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit B/N-terminal; ATPase-like, ATP-binding domain; SPTR: DNA gyrase subunit B; TIGRFAM: DNA gyrase, subunit B; IMG reference gene:2504585456; PFAM: Toprim domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; DNA gyrase B; DNA gyrase B subunit, carboxyl terminus; TIGRFAM: DNA gyrase, B subunit YP_004412454.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: dhd:Dhaf_4768 hypothetical protein; SPTR: ATPase; IMG reference gene:2504585457 YP_004412455.1 COGs: COG3412 conserved hypothetical protein; InterPro IPR012844:IPR004701; KEGG: elm:ELI_3082 dihydroxyacetone kinase; PFAM: Phosphotransferase system, fructose subfamily IIA component; SPTR: Dihydroxyacetone kinase, phosphotransfer subunit; TIGRFAM: Dihydroxyacetone kinase, subunit phosphotransferase; IMG reference gene:2504585458; PFAM: PTS system fructose IIA component; TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit YP_004412456.1 COGs: COG2376 Dihydroxyacetone kinase; InterPro IPR012737:IPR004007; KEGG: elm:ELI_3083 hypothetical protein; PFAM: Dak phosphatase; SPTR: Dihydroxyacetone kinase, L subunit; TIGRFAM: Dihydroxyacetone kinase, subunit L; IMG reference gene:2504585459; PFAM: DAK2 domain; TIGRFAM: dihydroxyacetone kinase, phosphoprotein-dependent, L subunit YP_004412457.1 COGs: COG0279 Phosphoheptose isomerase; InterPro IPR001347; KEGG: dma:DMR_p1_00410 putative phosphoheptose isomerase; PFAM: Sugar isomerase (SIS); SPTR: Phosphoheptose isomerase; IMG reference gene:2504585462; PFAM: SIS domain YP_004412458.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585463 YP_004412459.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585464 YP_004412460.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585465 YP_004412461.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR012763:IPR003593:IPR003959; KEGG: afn:Acfer_1728 DNA polymerase III, subunits gamma and tau; PFAM: ATPase, AAA-type, core; PRIAM: DNA-directed DNA polymerase; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, gamma and tau subunit; TIGRFAM: DNA polymerase III, subunit gamma/ tau; IMG reference gene:2504585467; PFAM: ATPase family associated with various cellular activities (AAA); DNA polymerase III subunits gamma and tau domain III; TIGRFAM: DNA polymerase III, delta' subunit; DNA polymerase III, subunit gamma and tau YP_004412462.1 COGs: COG0718 conserved hypothetical protein; InterPro IPR004401; KEGG: vpr:Vpar_1635 hypothetical protein; PFAM: Uncharacterised protein family UPF0133; SPTR: UPF0133 protein SELSPUOL_01346; TIGRFAM: Uncharacterised protein family UPF0133; IMG reference gene:2504585468; PFAM: Uncharacterised BCR, YbaB family COG0718; TIGRFAM: DNA-binding protein, YbaB/EbfC family YP_004412463.1 COGs: COG0353 Recombinational DNA repair protein (RecF pathway); InterPro IPR015967:IPR006171:IPR000093; KEGG: tjr:TherJR_0070 recombination protein RecR; SMART: Toprim domain; SPTR: Recombination protein recR; TIGRFAM: RecR protein; IMG reference gene:2504585469; PFAM: Toprim domain; RecR protein; TIGRFAM: recombination protein RecR YP_004412464.1 InterPro IPR010001; KEGG: cno:NT01CX_0822 sigma-K factor processing regulatory protein BofA; PFAM: SigmaK-factor processing regulatory BofA; SPTR: Sigma-K factor processing regulatory protein BofA; IMG reference gene:2504585470; PFAM: SigmaK-factor processing regulatory protein BofA; TIGRFAM: pro-sigmaK processing inhibitor BofA YP_004412465.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: vpr:Vpar_0600 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator family transporter; IMG reference gene:2504585471; PFAM: Major Facilitator Superfamily YP_004412466.1 KEGG: cow:Calow_2025 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585472 YP_004412467.1 COGs: COG1427 periplasmic solute-binding protein; InterPro IPR003773; KEGG: swo:Swol_1158 hypothetical protein; PFAM: Protein of unknown function DUF178; SPTR: Hypothetical cytosolic protein; IMG reference gene:2504585473; PFAM: Putative periplasminc binding protein (DUF178) YP_004412468.1 COGs: COG0351 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; InterPro IPR004399:IPR013749; KEGG: cac:CA_C3095 hydroxyethylthiazole kinase ThiM/ThiK; PFAM: Phosphomethylpyrimidine kinase type-1; PRIAM: Phosphomethylpyrimidine kinase; SPTR: Phosphomethylpyrimidine kinase; TIGRFAM: Phosphomethylpyrimidine kinase type-2; IMG reference gene:2504585474; PFAM: Phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase YP_004412469.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585475 YP_004412470.1 COGs: COG0035 Uracil phosphoribosyltransferase; InterPro IPR005765:IPR000836; KEGG: vpr:Vpar_1092 uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Uracil phosphoribosyltransferase; TIGRFAM: Uracil phosphoribosyl transferase; IMG reference gene:2504585477; PFAM: Phosphoribosyl transferase domain; TIGRFAM: uracil phosphoribosyltransferase YP_004412471.1 COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: vpr:Vpar_1093 glycine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Serine hydroxymethyltransferase; IMG reference gene:2504585478; PFAM: Serine hydroxymethyltransferase YP_004412472.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR006674; KEGG: vpr:Vpar_0618 Ppx/GppA phosphatase; PFAM: Ppx/GppA phosphatase; Metal-dependent phosphohydrolase, HD subdomain; PRIAM: Guanosine-5'-triphosphate,3'-diphosphate diphosphatase; SPTR: Exopolyphosphatase; IMG reference gene:2504585479; PFAM: HD domain; Ppx/GppA phosphatase family; TIGRFAM: exopolyphosphatase YP_004412473.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: pca:Pcar_2324 metalloendopeptidase-like membrane protein; PFAM: Peptidase M23; SPTR: Peptidase, M23/M37 family; IMG reference gene:2504585480; PFAM: Peptidase family M23 YP_004412474.1 COGs: COG1664 Integral membrane protein CcmA involved in cell shape determination; InterPro IPR007607; KEGG: aar:Acear_2337 protein of unknown function DUF583; PFAM: Protein of unknown function DUF583; SPTR: Putative uncharacterized protein; IMG reference gene:2504585481; PFAM: Protein of unknown function, DUF583 YP_004412475.1 KEGG: dhd:Dhaf_2399 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585482 YP_004412476.1 COGs: COG0274 Deoxyribose-phosphate aldolase; InterPro IPR002915:IPR011343; KEGG: afl:Aflv_2780 deoxyribose-phosphate aldolase; PFAM: Deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase; PRIAM: Deoxyribose-phosphate aldolase; SPTR: Deoxyribose-phosphate aldolase; TIGRFAM: Deoxyribose-phosphate aldolase; IMG reference gene:2504585484; PFAM: DeoC/LacD family aldolase; TIGRFAM: deoxyribose-phosphate aldolase YP_004412477.1 COGs: COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family; InterPro IPR003342; KEGG: afn:Acfer_0165 glycosyl transferase family 39; PFAM: Glycosyl transferase, family 39; SPTR: Putative cell division ATP-binding protein FtsE; IMG reference gene:2504585485; PFAM: Dolichyl-phosphate-mannose-protein mannosyltransferase YP_004412478.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: fnu:FN1223 dihydropteridine reductase; PFAM: Nitroreductase-like; SPTR: Oxygen-insensitive NAD(P)H nitroreductase; IMG reference gene:2504585486; PFAM: Nitroreductase family YP_004412479.1 COGs: COG1596 Periplasmic protein involved in polysaccharide export; InterPro IPR003715:IPR019554; KEGG: afn:Acfer_0563 polysaccharide export protein; PFAM: Polysaccharide export protein; Soluble ligand binding domain; SPTR: Putative polysaccharide export protein; IMG reference gene:2504585487; PFAM: Polysaccharide biosynthesis/export protein; SLBB domain YP_004412480.1 COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: vpr:Vpar_0670 lipopolysaccharide biosynthesis protein; PFAM: Lipopolysaccharide biosynthesis; SPTR: Putative chain length determinant protein; IMG reference gene:2504585488; PFAM: Chain length determinant protein YP_004412481.1 COGs: COG2148 Sugar transferase involved in lipopolysaccharide synthesis; InterPro IPR003362:IPR017475:IPR017472; KEGG: vpr:Vpar_0021 exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; PFAM: Bacterial sugar transferase; PRIAM: Undecaprenyl-phosphate galactose phosphotransferase; SPTR: Undecaprenyl-phosphate galactose phosphotransferase; TIGRFAM: Undecaprenyl-phosphate galactose phosphotransferase, WbaP; Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; IMG reference gene:2504585489; PFAM: Bacterial sugar transferase; TIGRFAM: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Undecaprenyl-phosphate galactose phosphotransferase, WbaP YP_004412482.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: hya:HY04AAS1_1578 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; manually curated; IMG reference gene:2504585490; PFAM: Glycosyl transferase family 2 YP_004412483.1 InterPro IPR007016; KEGG: cno:NT01CX_1531 hypothetical protein; PFAM: O-antigen ligase-related; SPTR: O-antigen polymerase family protein; IMG reference gene:2504585491; PFAM: O-Antigen ligase YP_004412484.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: mpo:Mpop_2183 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Lipopolysaccharide N-acetylglucosaminyltransferase; IMG reference gene:2504585492; PFAM: Glycosyl transferases group 1 YP_004412485.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585493 YP_004412486.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dae:Dtox_2838 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Mannosyltransferase; IMG reference gene:2504585494; PFAM: Glycosyl transferases group 1 YP_004412487.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509; KEGG: gur:Gura_3780 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; IMG reference gene:2504585495; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004412488.1 COGs: COG1089 GDP-D-mannose dehydratase; InterPro IPR001509:IPR006368; KEGG: cac:CA_C2180 GDP-D-mannose dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-mannose 4,6-dehydratase; SPTR: GDP-mannose 4,6-dehydratase; TIGRFAM: GDP-mannose 4,6-dehydratase; IMG reference gene:2504585496; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: GDP-mannose 4,6-dehydratase YP_004412489.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: bpb:bpr_I2578 NAD-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: GDP-L-fucose synthase; SPTR: GDP-L-fucose synthase; manually curated; IMG reference gene:2504585497; PFAM: NAD dependent epimerase/dehydratase family YP_004412490.1 COGs: COG2274 ABC-type bacteriocin/lantibiotic exporter contain an N-terminal double-glycine peptidase domain; InterPro IPR003593:IPR003439; KEGG: tel:tll0214 ATP-binding protein of ABC transporter; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ATP-binding protein of ABC transporter; IMG reference gene:2504585498; PFAM: ABC transporter YP_004412491.1 KEGG: tye:THEYE_A0483 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585499; PFAM: Capsule polysaccharide biosynthesis protein YP_004412492.1 COGs: COG1035 Coenzyme F420-reducing hydrogenase beta subunit; InterPro IPR001450:IPR007525; KEGG: amt:Amet_0212 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; PFAM: Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal; 4Fe-4S binding domain; SPTR: Dehydrogenase, beta subunit; IMG reference gene:2504585500; PFAM: 4Fe-4S binding domain; Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus YP_004412493.1 InterPro IPR007345; KEGG: smd:Smed_3879 hypothetical protein; PFAM: Polysaccharide pyruvyl transferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504585502; PFAM: Polysaccharide pyruvyl transferase YP_004412494.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001451; KEGG: bde:BDP_1853 acetyltransferase; SPTR: Nodulation protein l; IMG reference gene:2504585503 YP_004412495.1 COGs: COG1086 nucleoside-diphosphate sugar epimerase; InterPro IPR020025:IPR003869; KEGG: rpf:Rpic12D_0580 polysaccharide biosynthesis protein CapD; PFAM: Polysaccharide biosynthesis protein CapD-like; SPTR: UDP-N-acetylglucosamine 4,6-dehydratase; TIGRFAM: Pseudaminic acid biosynthesis, PseB; IMG reference gene:2504585504; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: UDP-N-acetylglucosamine 4,6-dehydratase YP_004412496.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653:IPR020026; KEGG: npu:Npun_R0689 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase; TIGRFAM: Pseudaminic acid biosynthesis, PseC; IMG reference gene:2504585505; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; TIGRFAM: UDP-4-keto-6-deoxy-N-acetylglucosamine 4-aminotransferase YP_004412497.1 COGs: COG0667 oxidoreductase (related to aryl-alcohol dehydrogenase); InterPro IPR023210; KEGG: swo:Swol_0202 oxidoreductase; PFAM: NADP-dependent oxidoreductase domain; SPTR: Putative oxidoreductase; IMG reference gene:2504585506; PFAM: Aldo/keto reductase family YP_004412498.1 COGs: COG1861 Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase homolog; InterPro IPR003329; KEGG: tai:Taci_0677 acylneuraminate cytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase; SPTR: Spore coat polysaccharide biosynthesis protein SpsF; IMG reference gene:2504585507; PFAM: Cytidylyltransferase YP_004412499.1 COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR005814; KEGG: cts:Ctha_2091 aminotransferase class-III; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde 2,1-aminomutase; IMG reference gene:2504585508; PFAM: Aminotransferase class-III YP_004412500.1 COGs: COG3980 Spore coat polysaccharide biosynthesis protein predicted glycosyltransferase; InterPro IPR007235:IPR020023; KEGG: bae:BATR1942_16230 pseudaminic acid biosynthesis-associated protein PseG; PFAM: Glycosyl transferase, family 28, C-terminal; SPTR: Pseudaminic acid biosynthesis-associated protein PseG; TIGRFAM: Pseudaminic acid biosynthesis-associated protein PseG; IMG reference gene:2504585509; PFAM: Glycosyltransferase family 28 C-terminal domain; TIGRFAM: pseudaminic acid biosynthesis-associated protein PseG YP_004412501.1 COGs: COG0223 Methionyl-tRNA formyltransferase; KEGG: swo:Swol_0208 methionyl-tRNA formyltransferase-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585510; PFAM: Formyl transferase YP_004412502.1 COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376; KEGG: cth:Cthe_2224 putative methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; SPTR: Putative methionyl-tRNA formyltransferase; IMG reference gene:2504585511; PFAM: Formyl transferase YP_004412503.1 COGs: COG2120 conserved hypothetical protein LmbE homologs; InterPro IPR003737; KEGG: swo:Swol_0211 putative LmbE-like protein; PFAM: N-acetylglucosaminyl phosphatidylinositol deacetylase; SPTR: N-acetylglucosaminylphosphatidylinositol deacetylase family protein; IMG reference gene:2504585512; PFAM: GlcNAc-PI de-N-acetylase YP_004412504.1 COGs: COG2089 Sialic acid synthase; InterPro IPR020030:IPR013974:IPR013132; KEGG: swo:Swol_0210 N-acylneuraminate-9-phosphate synthase; PFAM: N-acetylneuraminic acid synthase, N-terminal; SAF domain; PRIAM: N-acetylneuraminate synthase; SMART: SAF domain; SPTR: Pseudaminic acid synthase; TIGRFAM: Pseudaminic acid biosynthesis, PseI; IMG reference gene:2504585513; PFAM: SAF domain; NeuB family; TIGRFAM: pseudaminic acid synthase YP_004412505.1 COGs: COG0836 Mannose-1-phosphate guanylyltransferase; InterPro IPR005835:IPR013096; KEGG: bpb:bpr_I2267 mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase; PFAM: Nucleotidyl transferase; Cupin 2, conserved barrel; PRIAM: Mannose-1-phosphate guanylyltransferase; SPTR: Mannose-6-phosphate isomerase mannose-1-phosphate guanylyl transferase; IMG reference gene:2504585515; PFAM: Nucleotidyl transferase; Mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase YP_004412506.1 KEGG: bcr:BCAH187_E0057 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585517 YP_004412507.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585518 YP_004412508.1 KEGG: cbt:CLH_2472 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585519 YP_004412509.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585520; PFAM: Reverse transcriptase (RNA-dependent DNA polymerase) YP_004412510.1 KEGG: afn:Acfer_0728 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585521 YP_004412511.1 COGs: COG1106 ATPase; KEGG: clj:CLJU_c32430 hypothetical protein; SPTR: Putative abortive infection protein; IMG reference gene:2504585523 YP_004412512.1 KEGG: sfu:Sfum_3792 abortive phage resistance protein-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504585524 YP_004412513.1 InterPro IPR006311:IPR004843; KEGG: afn:Acfer_0329 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Putative metallophosphoesterase; IMG reference gene:2504585525; PFAM: Calcineurin-like phosphoesterase YP_004412514.1 COGs: COG3041 conserved hypothetical protein; InterPro IPR012753:IPR007712:IPR004386; KEGG: tde:TDE0505 hypothetical protein; PFAM: Plasmid stabilisation system; SPTR: Toxin-antitoxin system, toxin component, RelE family; TIGRFAM: Addiction module toxin, RelE/StbE; Conserved hypothetical protein CHP00053; IMG reference gene:2504585526; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin component, YafQ family; addiction module toxin, RelE/StbE family YP_004412515.1 InterPro IPR007337; KEGG: tde:TDE0302 hypothetical protein; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504585527; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004412516.1 COGs: COG2194 membrane-associated metal-dependent hydrolase; InterPro IPR000917; KEGG: vpr:Vpar_0824 sulfatase; PFAM: Sulfatase; SPTR: Integral membrane protein; IMG reference gene:2504585528; PFAM: Sulfatase YP_004412517.1 InterPro IPR002781; KEGG: bpu:BPUM_3167 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative membrane protein; IMG reference gene:2504585529; PFAM: Sulfite exporter TauE/SafE YP_004412518.1 KEGG: afl:Aflv_2564 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585530 YP_004412519.1 COGs: COG4784 Putative Zn-dependent protease; InterPro IPR019734:IPR001915:IPR001440; KEGG: afn:Acfer_2088 peptidase M48 Ste24p; PFAM: Peptidase M48; Tetratricopeptide TPR-1; SPTR: TPR domain protein; IMG reference gene:2504585532; PFAM: Peptidase family M48 YP_004412520.1 SPTR: NADH-ubiquinone oxidoreductase chain 3; IMG reference gene:2504585533 YP_004412521.1 COGs: COG1235 Metal-dependent hydrolase of the beta-lactamase superfamily I; InterPro IPR001279; KEGG: tmt:Tmath_2182 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: VicX protein; IMG reference gene:2504585534; PFAM: Metallo-beta-lactamase superfamily YP_004412522.1 KEGG: lma:LmjF34.0690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585535 YP_004412523.1 COGs: COG0692 Uracil DNA glycosylase; HAMAP: Uracil-DNA glycosylase; InterPro IPR002043:IPR005122; KEGG: gmc:GY4MC1_3764 uracil-DNA glycosylase; PFAM: Uracil-DNA glycosylase-like; SPTR: Uracil-DNA glycosylase; TIGRFAM: Uracil-DNA glycosylase; IMG reference gene:2504585536; PFAM: Uracil DNA glycosylase superfamily; TIGRFAM: uracil-DNA glycosylase YP_004412524.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR001638; KEGG: cdf:CD1476 putative signaling protein; PFAM: Diguanylate cyclase, predicted; Extracellular solute-binding protein, family 3; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504585537; PFAM: GGDEF domain; Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004412525.1 InterPro IPR019734:IPR013105:IPR001440; KEGG: afn:Acfer_1229 hypothetical protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SMART: Tetratricopeptide repeat; SPTR: Putative lipoprotein; IMG reference gene:2504585538; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Tetratricopeptide repeat YP_004412526.1 InterPro IPR006842; KEGG: tde:TDE0948 hypothetical protein; PFAM: Transposase (putative), YhgA-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504585539; PFAM: Putative transposase, YhgA-like; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004412527.1 COGs: COG2831 Hemolysin activation/secretion protein; InterPro IPR013686; KEGG: avn:Avin_37880 hypothetical protein; PFAM: Polypeptide-transport-associated, ShlB-type; SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504585540; PFAM: POTRA domain, ShlB-type YP_004412528.1 InterPro IPR006311:IPR008638:IPR011102; KEGG: mgm:Mmc1_2695 filamentous haemagglutinin outer membrane protein; PFAM: Filamentous haemagglutinin, N-terminal, bacterial; SMART: Signal transduction histidine kinase, HWE region; SPTR: Putative uncharacterized protein; TIGRFAM: Filamentous haemagglutinin, N-terminal, bacterial; Twin-arginine translocation pathway, signal sequence; IMG reference gene:2504585541; PFAM: haemagglutination activity domain; TIGRFAM: filamentous haemagglutinin family N-terminal domain YP_004412529.1 InterPro IPR008619; KEGG: pin:Ping_2394 filamentous haemagglutinin outer membrane protein; SPTR: Hemaglutinin repeat-containing domain protein; IMG reference gene:2504585542 YP_004412530.1 KEGG: tde:TDE0948 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585543; PFAM: Putative transposase, YhgA-like YP_004412531.1 InterPro IPR001119; KEGG: vpr:Vpar_0557 S-layer domain protein; PFAM: S-layer homology domain; SPTR: Putative S-layer domain protein; IMG reference gene:2504585544; PFAM: S-layer homology domain YP_004412532.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585545 YP_004412533.1 COGs: COG0474 Cation transport ATPase; InterProIPR006408:IPR001757:IPR004014:IPR008250:IPR 005834:IPR006068; KEGG: aoe:Clos_2053 calcium-translocating P-type ATPase, PMCA-type; PFAM: ATPase, P-type, ATPase-associated domain; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal; PRIAM: Calcium-transporting ATPase; SMART: ATPase, P-type cation-transporter, N-terminal; SPTR: Calcium-translocating P-type ATPase, PMCA-type; TIGRFAM: ATPase, P-type, calcium-transporting, PMCA-type; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504585546; PFAM: E1-E2 ATPase; Cation transporting ATPase, C-terminus; haloacid dehalogenase-like hydrolase; Cation transporter/ATPase, N-terminus; TIGRFAM: plasma-membrane calcium-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004412534.1 COGs: COG4110 Uncharacterized protein involved in stress response; InterPro IPR003325:IPR019303; KEGG: ppy:PPE_00942 tellurium resistance protein TerA; PFAM: Bacterial stress protein; Tellurium resistance; SPTR: Tellurium resistance protein TerA; IMG reference gene:2504585547; PFAM: Tellurium resistance protein; Bacterial stress protein YP_004412535.1 COGs: COG2310 Uncharacterized protein involved in stress response homologs of TerZ and putative cAMP-binding protein CABP1; InterPro IPR019303:IPR003325; KEGG: drm:Dred_0337 stress protein; PFAM: Bacterial stress protein; Tellurium resistance; SPTR: Tellurium resistance protein TerD; IMG reference gene:2504585548; PFAM: Tellurium resistance protein; Bacterial stress protein YP_004412536.1 COGs: COG2310 Uncharacterized protein involved in stress response homologs of TerZ and putative cAMP-binding protein CABP1; InterPro IPR003325; KEGG: ctc:CTC02234 tellurium resistance protein TerD; PFAM: Bacterial stress protein; SPTR: Tellurium resistance protein TerD; IMG reference gene:2504585549; PFAM: Bacterial stress protein YP_004412537.1 COGs: COG2013 conserved hypothetical protein; InterPro IPR002838; KEGG: dae:Dtox_1044 protein of unknown function DUF124; PFAM: Protein of unknown function DUF124; SPTR: Putative uncharacterized protein; TIGRFAM: Protein of unknown function DUF124; IMG reference gene:2504585550; PFAM: Protein of unknown function DUF124; TIGRFAM: TIGR00266 family protein YP_004412538.1 COGs: COG2310 Uncharacterized protein involved in stress response homologs of TerZ and putative cAMP-binding protein CABP1; InterPro IPR003325; KEGG: cno:NT01CX_0666 stress protein; PFAM: Bacterial stress protein; SPTR: Tellurium resistance protein TerD; IMG reference gene:2504585551; PFAM: Bacterial stress protein YP_004412539.1 COGs: COG2310 Uncharacterized protein involved in stress response homologs of TerZ and putative cAMP-binding protein CABP1; InterPro IPR003325; KEGG: dae:Dtox_2988 stress protein; PFAM: Bacterial stress protein; SPTR: Tellurium resistance protein TerD; IMG reference gene:2504585552; PFAM: Bacterial stress protein YP_004412540.1 COGs: COG2301 Citrate lyase beta subunit; KEGG: ppm:PPSC2_c1007 citrate lyase beta subunit-like protein; SPTR: Putative ATP/GTP-binding protein; IMG reference gene:2504585553 YP_004412541.1 KEGG: bbe:BBR47_58710 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585554 YP_004412542.1 InterPro IPR000836:IPR022537; KEGG: nwa:Nwat_2032 hypothetical protein; PFAM: Domain of unknown function DUF3706; Phosphoribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504585555; PFAM: Phosphoribosyl transferase domain; Protein of unknown function (DUF3706) YP_004412543.1 KEGG: aoe:Clos_0704 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585556; PFAM: Protein of unknown function (DUF2983) YP_004412544.1 InterPro IPR013200; KEGG: fri:FraEuI1c_0978 hypothetical protein; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Putative uncharacterized protein; IMG reference gene:2504585557 YP_004412545.1 KEGG: ere:EUBREC_1097 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585558 YP_004412546.1 COGs: COG1670 Acetyltransferase including N-acetylase of ribosomal protein; InterPro IPR000182; KEGG: cst:CLOST_0135 gcn5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative spermidine N1-acetyltransferase; IMG reference gene:2504585559; PFAM: Acetyltransferase (GNAT) family YP_004412547.1 COGs: COG1015 Phosphopentomutase; InterPro IPR010045:IPR006124; KEGG: cpy:Cphy_3719 phosphopentomutase; PFAM: Metalloenzyme; PRIAM: Phosphopentomutase; SPTR: Phosphopentomutase; TIGRFAM: Phosphopentomutase; IMG reference gene:2504585560; PFAM: Metalloenzyme superfamily; TIGRFAM: phosphopentomutase YP_004412548.1 InterPro IPR001119; KEGG: afn:Acfer_1669 S-layer domain protein; PFAM: S-layer homology domain; SPTR: Porin; major outer membrane protein; IMG reference gene:2504585561; PFAM: S-layer homology domain YP_004412549.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585562 YP_004412550.1 InterPro IPR021321; PFAM: Protein of unknown function DUF2922; SPTR: Putative uncharacterized protein; IMG reference gene:2504585563; PFAM: Protein of unknown function (DUF2922) YP_004412551.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585564 YP_004412552.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: amt:Amet_3255 two component, sigma54 specific, Fis family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Chemotaxis protein CheY; IMG reference gene:2504585565; PFAM: Response regulator receiver domain YP_004412553.1 KEGG: hmo:HM1_2628 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585566 YP_004412554.1 COGs: COG1740 Ni Fe-hydrogenase I small subunit; InterPro IPR001821:IPR006311:IPR006137; KEGG: vpr:Vpar_1188 hydrogenase (NiFe) small subunit HydA; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: Hydrogenase (acceptor); SPTR: Quinone-reactive Ni/Fe-hydrogenase, small subunit; TIGRFAM: [Ni-Fe]-hydrogenase, small subunit; Twin-arginine translocation pathway, signal sequence; IMG reference gene:2504585568; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: hydrogenase (NiFe) small subunit (hydA) YP_004412555.1 COGs: COG0374 Ni Fe-hydrogenase I large subunit; InterPro IPR001501; KEGG: vpr:Vpar_1187 nickel-dependent hydrogenase large subunit; PFAM: Nickel-dependent hydrogenase, large subunit; PRIAM: Cytochrome-c3 hydrogenase; SPTR: Uptake hydrogenase large subunit; IMG reference gene:2504585569; PFAM: Nickel-dependent hydrogenase YP_004412556.1 COGs: COG1969 Ni Fe-hydrogenase I cytochrome b subunit; InterPro IPR000516:IPR005797; KEGG: tal:Thal_1107 Ni/Fe-hydrogenase, b-type cytochrome subunit; PFAM: Cytochrome b/b6, N-terminal; SPTR: Ni/Fe-hydrogenase, B-type cytochrome subunit; TIGRFAM: Nickel-dependent hydrogenase b-type cytochrome subunit; IMG reference gene:2504585570; PFAM: Cytochrome b(N-terminal)/b6/petB; TIGRFAM: Ni/Fe-hydrogenase, b-type cytochrome subunit YP_004412557.1 SPTR: Conserved domain protein; IMG reference gene:2504585571 YP_004412558.1 COGs: COG0375 Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); HAMAP: Hydrogenase nickel incorporation protein HypA/HybF; InterPro IPR000688; KEGG: vpr:Vpar_1518 hydrogenase expression/synthesis HypA; PFAM: Hydrogenase nickel incorporation protein HypA/HybF; SPTR: Hydrogenase nickel insertion protein HypA; TIGRFAM: Hydrogenase nickel incorporation protein HypA/HybF; IMG reference gene:2504585572; PFAM: Hydrogenase expression/synthesis hypA family; TIGRFAM: hydrogenase nickel insertion protein HypA YP_004412559.1 COGs: COG0378 Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase; InterPro IPR004392:IPR003495; KEGG: hmo:HM1_1483 hydrogenase accessory protein HypB; PFAM: Cobalamin (vitamin B12) biosynthesis CobW-like; SPTR: Hydrogenase accessory protein HypB; TIGRFAM: Hydrogenase accessory protein HypB; IMG reference gene:2504585573; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB YP_004412560.1 COGs: COG0680 Ni Fe-hydrogenase maturation factor; InterPro IPR000671; KEGG: aae:aq_667 HupD hydrogenase related function; PFAM: Peptidase A31, hydrogen uptake protein; SPTR: Ribulose bisphosphate carboxylase, small subunit; TIGRFAM: Peptidase A31, hydrogen uptake protein; IMG reference gene:2504585574; PFAM: Hydrogenase maturation protease; TIGRFAM: hydrogenase expression/formation protein; hydrogenase maturation protease YP_004412561.1 COGs: COG0298 Hydrogenase maturation factor; InterPro IPR001109; KEGG: deb:DehaBAV1_1241 hydrogenase assembly chaperone HypC/HupF; PFAM: Hydrogenase expression/formation protein, HupF/HypC; SPTR: Hydrogenase assembly chaperone HypC/HupF; TIGRFAM: Hydrogenase expression/formation protein, HupF/HypC; IMG reference gene:2504585575; PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF YP_004412562.1 COGs: COG0409 Hydrogenase maturation factor; InterPro IPR002780; KEGG: gme:Gmet_0117 hydrogenase formation HypD protein; PFAM: Hydrogenase formation HypD protein; SPTR: Hydrogenase expression/formation protein HypD; TIGRFAM: Hydrogenase formation HypD protein; IMG reference gene:2504585576; PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD YP_004412563.1 COGs: COG0309 Hydrogenase maturation factor; InterPro IPR011854:IPR000728:IPR010918; KEGG: dly:Dehly_1413 hydrogenase expression/formation protein HypE; PFAM: AIR synthase-related protein; AIR synthase-related protein, C-terminal; SPTR: Hydrogenase expression/formation protein HypE; TIGRFAM: Hydrogenase expression/formation protein HypE; IMG reference gene:2504585577; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE YP_004412564.1 KEGG: vpr:Vpar_1007 hypothetical protein; SPTR: Putative BioX protein; IMG reference gene:2504585578 YP_004412565.1 COGs: COG0156 7-keto-8-aminopelargonate synthetase; InterPro IPR004839:IPR004723:IPR005499; KEGG: ckp:ckrop_1506 pimeloyl-CoA synthetase/8-amino-7-oxononanoate synthase; PFAM: 6-carboxyhexanoate--CoA ligase; Aminotransferase, class I/classII; PRIAM: 6-carboxyhexanoate--CoA ligase., 8-amino-7-oxononanoate synthase; SPTR: Glycine C-acetyltransferase; TIGRFAM: 8-amino-7-oxononanoate synthase/2-amino-3-ketobutyrate coenzyme A ligase; IMG reference gene:2504585579; PFAM: 6-carboxyhexanoate--CoA ligase; Aminotransferase class I and II; TIGRFAM: 8-amino-7-oxononanoate synthase; 6-carboxyhexanoate--CoA ligase YP_004412566.1 COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327; KEGG: lba:Lebu_2246 DNA adenine methylase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: DNA adenine methylase; TIGRFAM: D12 class N6 adenine-specific DNA methyltransferase; IMG reference gene:2504585580; PFAM: D12 class N6 adenine-specific DNA methyltransferase; TIGRFAM: DNA adenine methylase (dam) YP_004412567.1 SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504585581 YP_004412568.1 COGs: COG1757 Na+/H+ antiporter; InterPro IPR018461; KEGG: cpy:Cphy_1066 Na+/H+ antiporter NhaC; PFAM: Na+/H+ antiporter NhaC-like; SPTR: Na+/H+ antiporter family protein; IMG reference gene:2504585582; PFAM: Na+/H+ antiporter family YP_004412569.1 InterPro IPR007197; KEGG: fsu:Fisuc_1354 radical SAM domain protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504585583; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM protein, TatD family-associated YP_004412570.1 COGs: COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway); InterPro IPR002529; KEGG: aac:Aaci_2886 5-carboxymethyl-2-hydroxymuconateDelta-isomerase; PFAM: Fumarylacetoacetase, C-terminal-like; PRIAM: 5-carboxymethyl-2-hydroxymuconate Delta-isomerase; SPTR: Fumarylacetoacetate hydrolase family protein; IMG reference gene:2504585584; PFAM: Fumarylacetoacetate (FAA) hydrolase family YP_004412571.1 KEGG: chy:CHY_0146 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585585 YP_004412572.1 InterPro IPR020483; KEGG: vpa:VPA0976 hypothetical protein; PFAM: Uncharacterised protein family YgbA; SPTR: Putative uncharacterized protein; IMG reference gene:2504585586; PFAM: Nitrous oxide-stimulated promoter YP_004412573.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712:IPR008595; KEGG: nth:Nther_2326 histidine kinase; PFAM: Sensor DegS; Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Histidine kinase; IMG reference gene:2504585587; PFAM: Histidine kinase; Sensor protein DegS; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004412574.1 COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: sth:STH3269 arginine/lysine/ornithine decarboxylase; PFAM: Orn/Lys/Arg decarboxylase, major domain; Orn/Lys/Arg decarboxylase, C-terminal; PRIAM: Arginine decarboxylase; SPTR: Lysine decarboxylase; IMG reference gene:2504585588; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain YP_004412575.1 COGs: COG1091 dTDP-4-dehydrorhamnose reductase; InterPro IPR005913; KEGG: csh:Closa_0401 dTDP-4-dehydrorhamnose reductase; PFAM: dTDP-4-dehydrorhamnose reductase; PRIAM: dTDP-4-dehydrorhamnose reductase; SPTR: dTDP-4-dehydrorhamnose reductase; TIGRFAM: dTDP-4-dehydrorhamnose reductase; IMG reference gene:2504585589; PFAM: RmlD substrate binding domain; TIGRFAM: dTDP-4-dehydrorhamnose reductase YP_004412576.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: hmo:HM1_1189 nad-dependent epimerase/dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; IMG reference gene:2504585590; PFAM: NAD dependent epimerase/dehydratase family YP_004412577.1 InterPro IPR013096; KEGG: dhd:Dhaf_0788 cupin 2 conserved barrel domain protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative mannose-6-phosphate isomerase; IMG reference gene:2504585591; PFAM: Cupin domain YP_004412578.1 COGs: COG1434 conserved hypothetical protein; InterPro IPR003848; KEGG: ppm:PPSC2_c3685 protein of hypothetical function duf218; PFAM: Domain of unknown function DUF218; SPTR: Putative membrane protein; IMG reference gene:2504585592; PFAM: DUF218 domain YP_004412579.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: gym:GYMC10_3705 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504585593; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_004412580.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: sab:SAB2287c hypothetical protein; PFAM: Addiction module toxin, Txe/YoeB; SPTR: Addiction module toxin, Txe/YoeB family; TIGRFAM: Addiction module toxin, Txe/YoeB; IMG reference gene:2504585594; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_004412581.1 InterPro IPR006442; KEGG: ere:EUBREC_0316 hypothetical protein; PFAM: Prevent-host-death protein; SPTR: Toxin-antitoxin system, antitoxin component, PHD family; IMG reference gene:2504585595; PFAM: Phd_YefM YP_004412582.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: bth:BT_4728 putative hexose phosphate transport protein; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative regulatory protein UhpC; IMG reference gene:2504585596; PFAM: Major Facilitator Superfamily YP_004412583.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: tro:trd_A0295 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585597; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412584.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: afn:Acfer_1125 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase CwlB; IMG reference gene:2504585598; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004412585.1 InterPro IPR010106; KEGG: afn:Acfer_1503 tetracycline resistance leader peptide; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504585599; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004412586.1 COGs: COG0838 NADH:ubiquinone oxidoreductase subunit 3 (chain A); InterPro IPR000440; KEGG: cbe:Cbei_2996 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 3; SPTR: NADH-quinone oxidoreductase subunit; IMG reference gene:2504585600; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 YP_004412587.1 COGs: COG0377 NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductase; InterPro IPR006137:IPR006138; KEGG: hmo:HM1_2197 NADH dehydrogenase subunit B; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit B; TIGRFAM: NADH-ubiquinone oxidoreductase, 20 Kd subunit; IMG reference gene:2504585601; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit; TIGRFAM: NADH-quinone oxidoreductase, B subunit YP_004412588.1 COGs: COG0852 NADH:ubiquinone oxidoreductase 27 kD subunit; InterPro IPR001268; KEGG: mta:Moth_0979 NADH (or F420H2) dehydrogenase, subunit C; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; SPTR: NADH-quinone oxidoreductase; IMG reference gene:2504585602; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit YP_004412589.1 COGs: COG0649 NADH:ubiquinone oxidoreductase 49 kD subunit 7; InterPro IPR001135; KEGG: hmo:HM1_2199 proton-translocating NADH-ubiquinone oxidoreductase, chain D; PFAM: NADH-quinone oxidoreductase, subunit D; PRIAM: NADH dehydrogenase (quinone); SPTR: Proton-translocating NADH-quinone oxidoreductase, D subunit; IMG reference gene:2504585603; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit YP_004412590.1 COGs: COG1005 NADH:ubiquinone oxidoreductase subunit 1 (chain H); InterPro IPR001694; KEGG: mta:Moth_0981 respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I, H subunit; IMG reference gene:2504585604; PFAM: NADH dehydrogenase YP_004412591.1 COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); InterPro IPR001450; KEGG: hmo:HM1_2201 proton-translocating NADH-ubiquinone oxidoreductase, 23 kd, chain I; PFAM: 4Fe-4S binding domain; SPTR: NADH-quinone oxidoreductase, I subunit; IMG reference gene:2504585605; PFAM: 4Fe-4S binding domain; TIGRFAM: NADH-quinone oxidoreductase, chain I YP_004412592.1 COGs: COG0839 NADH:ubiquinone oxidoreductase subunit 6 (chain J); InterPro IPR001457; KEGG: hmo:HM1_2202 proton-translocating NADH-ubiquinone oxidoreductase, chain J; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase, chain 6; SPTR: NADH dehydrogenase I, J subunit; IMG reference gene:2504585606; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 6 YP_004412593.1 COGs: COG0713 NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); InterPro IPR001133; KEGG: chy:CHY_1418 proton-translocating NADH-quinone oxidoreductase subunit K; PFAM: NADH-ubiquinone oxidoreductase chain 4L/K; SPTR: NADH-quinone oxidoreductase subunit K; IMG reference gene:2504585607; PFAM: NADH-ubiquinone/plastoquinone oxidoreductase chain 4L YP_004412594.1 COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR003945:IPR001516:IPR001750; KEGG: hmo:HM1_2204 proton-translocating NADH-ubiquinone oxidoreductase, chain L; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; NADH:ubiquinone oxidoreductase, chain 5/L, N-terminal; PRIAM: NADH dehydrogenase (quinone); SPTR: Proton-translocating NADH-quinone oxidoreductase, L subunit; TIGRFAM: NADH-plastoquinone oxidoreductase, chain 5; IMG reference gene:2504585608; PFAM: NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L YP_004412595.1 COGs: COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M); InterPro IPR010227:IPR001750; KEGG: hmo:HM1_2205 proton-translocating NADH-ubiquinone oxidoreductase, chain M; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I, M subunit; TIGRFAM: NADH-quinone oxidoreductase, chain M/4; IMG reference gene:2504585609; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain M YP_004412596.1 COGs: COG1007 NADH:ubiquinone oxidoreductase subunit 2 (chain N); InterPro IPR010096:IPR001750; KEGG: hmo:HM1_2206 proton-translocating NADH-ubiquinone oxidoreductase, chain N; PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-quinone oxidoreductase subunit N; TIGRFAM: NAD(P)H-quinone oxidoreductase, subunit N/subunit 2; IMG reference gene:2504585610; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain N YP_004412597.1 KEGG: rrs:RoseRS_0279 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585611 YP_004412598.1 InterPro IPR018647; KEGG: cbe:Cbei_2021 hypothetical protein; PFAM: Protein of unknown function DUF2075; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504585612; PFAM: Uncharacterized conserved protein (DUF2075) YP_004412599.1 KEGG: ere:EUBREC_2827 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585613 YP_004412600.1 COGs: COG3666 Transposase and inactivated derivatives; InterPro IPR002559:IPR008490; KEGG: bpb:bpr_IV196 IS4 family transposase; SPTR: ISCpe5, transposase; IMG reference gene:2504585614; PFAM: Transposase DDE domain; Transposase domain (DUF772) YP_004412601.1 KEGG: csc:Csac_0013 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585616 YP_004412602.1 KEGG: cbe:Cbei_3559 transcriptional regulator-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585617 YP_004412603.1 KEGG: vpr:Vpar_1822 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585618 YP_004412604.1 KEGG: vpr:Vpar_1818 CRISPR-associated protein, putative; SPTR: Putative uncharacterized protein; IMG reference gene:2504585619 YP_004412605.1 KEGG: vpr:Vpar_1822 hypothetical protein; SPTR: Putative 30S ribosomal protein S20; IMG reference gene:2504585620; PFAM: CRISPR-associated protein (cas_TM1812) YP_004412606.1 KEGG: vpr:Vpar_1817 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585622 YP_004412607.1 KEGG: vpr:Vpar_1816 protein of unknown function DUF324; SPTR: Putative uncharacterized protein; IMG reference gene:2504585623 YP_004412608.1 KEGG: vpr:Vpar_1815 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585624 YP_004412609.1 COGs: COG1337 Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily); InterPro IPR005537; KEGG: vpr:Vpar_1814 protein of unknown function DUF324; PFAM: Protein of unknown function DUF324; SPTR: CRISPR-associated RAMP protein; IMG reference gene:2504585625; PFAM: RAMP superfamily YP_004412610.1 KEGG: vpr:Vpar_1813 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585626; TIGRFAM: CRISPR-associated protein, TIGR03984 family YP_004412611.1 InterPro IPR005537; KEGG: vpr:Vpar_1812 protein of unknown function DUF324; PFAM: Protein of unknown function DUF324; SPTR: Putative uncharacterized protein; IMG reference gene:2504585627; PFAM: RAMP superfamily; TIGRFAM: CRISPR-associated protein YP_004412612.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; InterPro IPR004527:IPR020058; KEGG: clo:HMPREF0868_0766 glutamate--tRNA ligase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; PRIAM: Glutamate--tRNA ligase; SPTR: Glutamate--tRNA ligase; TIGRFAM: Glutamyl-tRNA synthetase, class Ic, bacterial/mitochondrial; IMG reference gene:2504585629; PFAM: tRNA synthetases class I (E and Q), catalytic domain; TIGRFAM: glutamyl-tRNA synthetase, bacterial family YP_004412613.1 COGs: COG2968 conserved hypothetical protein; InterPro IPR007497; KEGG: gau:GAU_0029 hypothetical protein; PFAM: Protein of unknown function DUF541; SPTR: Putativeouter membrane protein; IMG reference gene:2504585630; PFAM: Protein of unknown function (DUF541) YP_004412614.1 KEGG: afn:Acfer_1670 S-layer domain protein; SPTR: Putative translation initiation factor IF-2; IMG reference gene:2504585631 YP_004412615.1 COGs: COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase; InterPro IPR017476:IPR014027:IPR001732:IPR014026; KEGG: cth:Cthe_2340 UDP-glucose/GDP-mannose dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase, N-terminal; UDP-glucose/GDP-mannose dehydrogenase, C-terminal; UDP-glucose/GDP-mannose dehydrogenase, dimerisation; PRIAM: UDP-glucose 6-dehydrogenase; SPTR: UDP-glucose/GDP-mannose dehydrogenase family protein; TIGRFAM: Nucleotide sugar dehydrogenase; IMG reference gene:2504585632; PFAM: UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; UDP-glucose/GDP-mannose dehydrogenase family, central domain; UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; TIGRFAM: nucleotide sugar dehydrogenase YP_004412616.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: cpy:Cphy_2213 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase; IMG reference gene:2504585633; PFAM: Polysaccharide deacetylase YP_004412617.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR009875:IPR001173; KEGG: cpy:Cphy_2212 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; Type IV pilus assembly PilZ; PRIAM: Hyaluronan synthase; SPTR: Chitin synthase; IMG reference gene:2504585634; PFAM: Glycosyl transferase family 2; PilZ domain YP_004412618.1 KEGG: cpy:Cphy_2211 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585635 YP_004412619.1 COGs: COG3858 glycosyl hydrolase; KEGG: gym:GYMC10_2039 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504585636; PFAM: Glycosyl hydrolases family 18 YP_004412620.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: cpy:Cphy_2213 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Putative polysaccharide deacetylase; IMG reference gene:2504585637; PFAM: Polysaccharide deacetylase YP_004412621.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR007197; KEGG: afn:Acfer_0102 radical SAM domain protein; PFAM: Radical SAM; SPTR: Glutamate 5-kinase; IMG reference gene:2504585638; PFAM: Radical SAM superfamily YP_004412622.1 COGs: COG2078 conserved hypothetical protein; InterPro IPR004183:IPR002733; KEGG: elm:ELI_2034 3,4-dihydroxyphenylacetate 2,3-dioxygenase, AMMECR1 domain protein; PFAM: AMMECR1; Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B; SPTR: 3,4-dihydroxyphenylacetate 2,3-dioxygenase, AMMECR1 domain protein; TIGRFAM: AMMECR1; IMG reference gene:2504585639; PFAM: AMMECR1; Catalytic LigB subunit of aromatic ring-opening dioxygenase; TIGRFAM: uncharacterized protein, PH0010 family YP_004412623.1 KEGG: afn:Acfer_0837 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585640 YP_004412624.1 COGs: COG1027 Aspartate ammonia-lyase; InterPro IPR022761:IPR018951; KEGG: vpr:Vpar_1504 fumarate lyase; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal; PRIAM: Aspartate ammonia-lyase; SPTR: Aspartate ammonia-lyase; IMG reference gene:2504585641; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: aspartate ammonia-lyase YP_004412625.1 SPTR: Putative 8-amino-7-oxononanoate synthase; IMG reference gene:2504585642 YP_004412626.1 InterPro IPR001387; KEGG: vei:Veis_4125 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504585643; PFAM: Helix-turn-helix YP_004412627.1 COGs: COG1313 Uncharacterized Fe-S protein PflX homolog of pyruvate formate lyase activating protein; InterPro IPR007197; KEGG: cno:NT01CX_1001 uncharacterized Fe-S protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504585644; PFAM: Radical SAM superfamily YP_004412628.1 COGs: COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR000917; KEGG: vpr:Vpar_0015 sulfatase; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585645; PFAM: Sulfatase YP_004412629.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: cbe:Cbei_0466 DeoR family transcriptional regulator; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504585646; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004412630.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: afn:Acfer_0056 BioY protein; PFAM: BioY protein; SPTR: BioY family protein; IMG reference gene:2504585647; PFAM: BioY family YP_004412631.1 COGs: COG0132 Dethiobiotin synthetase; InterPro IPR002586:IPR004472; KEGG: afn:Acfer_0057 dethiobiotin synthase; PFAM: Cobyrinic acid a,c-diamide synthase; PRIAM: Dethiobiotin synthase; SPTR: Dethiobiotin synthetase; TIGRFAM: Dethiobiotin synthase; IMG reference gene:2504585648; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: dethiobiotin synthase YP_004412632.1 COGs: COG0161 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; InterPro IPR005814:IPR005815; KEGG: afn:Acfer_0058 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Adenosylmethionine--8-amino-7-oxononanoate transaminase; SPTR: Adenosylmethionine-8-amino-7-oxononanoate transaminase; TIGRFAM: Adenosylmethionine--8-amino-7-oxononanoate aminotransferase; IMG reference gene:2504585649; PFAM: Aminotransferase class-III; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate transaminase YP_004412633.1 COGs: COG2893 Phosphotransferase system mannose/fructose-specific component IIA; InterPro IPR013789:IPR004701; KEGG: ppy:PPE_01463 phosphotransferase system, mannose/fructose-specific component IIA; PFAM: Phosphotransferase system, fructose subfamily IIA component; SPTR: PTS system mannose-specific EIIAB component; TIGRFAM: Phosphotransferase system, fructose subfamily IIA component, subgroup; IMG reference gene:2504585650; PFAM: PTS system fructose IIA component; TIGRFAM: PTS system, mannose/fructose/sorbose family, IIA component YP_004412634.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR012828:IPR000023; KEGG: hmo:HM1_0078 6-phosphofructokinase; PFAM: Phosphofructokinase domain; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase; TIGRFAM: 6-phosphofructokinase; IMG reference gene:2504585651; PFAM: Phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004412635.1 InterPro IPR000846:IPR010190; KEGG: bpb:bpr_I0298 diaminopimelate dehydrogenase; PFAM: Dihydrodipicolinate reductase, N-terminal; PRIAM: Diaminopimelate dehydrogenase; SPTR: Diaminopimelate dehydrogenase; TIGRFAM: Diaminopimelate dehydrogenase; IMG reference gene:2504585652; PFAM: Dihydrodipicolinate reductase, N-terminus; TIGRFAM: diaminopimelate dehydrogenase YP_004412636.1 COGs: COG2962 permease; InterPro IPR000620:IPR004626; KEGG: vpr:Vpar_1764 RarD protein, DMT superfamily transporter; PFAM: Drug/metabolite transporter; SPTR: Protein RarD; TIGRFAM: RarD protein; IMG reference gene:2504585653; PFAM: EamA-like transporter family; TIGRFAM: rarD protein YP_004412637.1 COGs: COG3859 membrane protein; InterPro IPR012651; KEGG: ckr:CKR_1784 hypothetical protein; PFAM: Thiamine transporter YuaJ; SPTR: Putative proton-coupled thiamine transporter YuaJ; TIGRFAM: Thiamine transporter YuaJ; IMG reference gene:2504585654; PFAM: Thiamine transporter protein (Thia_YuaJ); TIGRFAM: putative proton-coupled thiamine transporter YuaJ YP_004412638.1 COGs: COG1835 acyltransferase; InterPro IPR002656; KEGG: efa:EF0783 acyltransferase, putative; PFAM: Acyltransferase 3; SPTR: Acyltransferase 3; IMG reference gene:2504585655; PFAM: Acyltransferase family YP_004412639.1 KEGG: ttm:Tthe_1877 YcfA family protein; SPTR: Toxin-antitoxin system, toxin component, HicA family; IMG reference gene:2504585656 YP_004412640.1 COGs: COG1598 conserved hypothetical protein; InterPro IPR005357:IPR008651; KEGG: pth:PTH_2782 hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, HicB family; IMG reference gene:2504585657; PFAM: HicB family; Uncharacterised protein family (UPF0150) YP_004412641.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585658 YP_004412642.1 KEGG: sus:Acid_6029 PEGA domain-containing protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585659 YP_004412643.1 InterPro IPR010652; KEGG: pam:PANA_2553 hypothetical protein; PFAM: Protein of unknown function DUF1232; SPTR: Putative membrane protein; IMG reference gene:2504585660; PFAM: Protein of unknown function (DUF1232) YP_004412644.1 COGs: COG3152 membrane protein; InterPro IPR008523; KEGG: pfs:PFLU5551 hypothetical protein; PFAM: Protein of unknown function DUF805; SPTR: Putative cell division protein FtsK; IMG reference gene:2504585661; PFAM: Protein of unknown function (DUF805) YP_004412645.1 KEGG: afn:Acfer_0870 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585662 YP_004412646.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: cce:Ccel_3266 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504585666; PFAM: Transposase IS200 like YP_004412647.1 KEGG: lmc:Lm4b_00645 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585667 YP_004412648.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR002290:IPR020635:IPR017442; KEGG: lmh:LMHCC_2012 protein kinase domain protein; PFAM: Serine/threonine-protein kinase-like domain; SMART: Serine/threonine-protein kinase domain; Tyrosine-protein kinase, catalytic domain; SPTR: Protein kinase domain protein; IMG reference gene:2504585668; PFAM: Protein kinase domain YP_004412649.1 SPTR: TcdA-E operon negative regulator; IMG reference gene:2504585669 YP_004412650.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585670 YP_004412651.1 KEGG: afn:Acfer_0433 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585671 YP_004412652.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: ctc:CTC01487 methyl-accepting chemotaxis-like protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585672; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412653.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: cbt:CLH_2034 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor; PFAM: Diguanylate cyclase, predicted; SPTR: Putative sensory box protein/GGDEF domain protein; IMG reference gene:2504585673; PFAM: GGDEF domain YP_004412654.1 COGs: COG0586 membrane-associated protein; InterPro IPR015414; KEGG: mta:Moth_0719 hypothetical protein; PFAM: SNARE associated Golgi protein; SPTR: DedA family protein; IMG reference gene:2504585674; PFAM: SNARE associated Golgi protein YP_004412655.1 COGs: COG0679 permease; InterPro IPR004776; KEGG: sat:SYN_03357 hypothetical protein; PFAM: Auxin efflux carrier; SPTR: Transporter, auxin efflux carrier family; IMG reference gene:2504585675; PFAM: Membrane transport protein YP_004412656.1 COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: cce:Ccel_1179 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2504585676; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I YP_004412657.1 InterPro IPR021330; PFAM: Protein of unknown function DUF2939; SPTR: Putative uncharacterized protein; IMG reference gene:2504585677; PFAM: Protein of unknown function (DUF2939) YP_004412658.1 InterPro IPR007404; KEGG: ppd:Ppro_3763 membrane-bound metal-dependent hydrolase; PFAM: Protein of unknown function DUF457, transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504585678; PFAM: Predicted membrane-bound metal-dependent hydrolase (DUF457) YP_004412659.1 COGs: COG3855 conserved hypothetical protein; HAMAP: Fructose-1,6-bisphosphatase, Bacillus type; InterPro IPR009164; KEGG: ols:Olsu_1042 fructose-16-bisphosphatase; PFAM: Fructose-1,6-bisphosphatase, Bacillus type; PRIAM: Fructose-bisphosphatase; SPTR: Fructose-1,6-bisphosphatase class 3; IMG reference gene:2504585679; PFAM: Firmicute fructose-1,6-bisphosphatase YP_004412660.1 COGs: COG1342 DNA-binding protein; InterPro IPR002852:IPR003731; KEGG: ere:EUBREC_1223 putative DNA-binding protein; PFAM: Uncharacterised protein family UPF0251; Dinitrogenase iron-molybdenum cofactor biosynthesis; SPTR: Putative DNA-binding protein; IMG reference gene:2504585680; PFAM: Protein of unknown function DUF134; Dinitrogenase iron-molybdenum cofactor YP_004412661.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR001327; KEGG: cno:NT01CX_2374 thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin-disulfide reductase; IMG reference gene:2504585681; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: thioredoxin-disulfide reductase YP_004412662.1 InterPro IPR002109; KEGG: cno:NT01CX_2375 glutaredoxin; PFAM: Glutaredoxin; SPTR: Glutaredoxin; IMG reference gene:2504585682; PFAM: Glutaredoxin; TIGRFAM: Glutaredoxin-like protein, YruB-family YP_004412663.1 COGs: COG0766 UDP-N-acetylglucosamine enolpyruvyl transferase; InterPro IPR001986:IPR005750; KEGG: vpr:Vpar_0517 UDP-N-acetylglucosamine1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; SPTR: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase; IMG reference gene:2504585683; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_004412664.1 COGs: COG0302 GTP cyclohydrolase I; InterPro IPR020602; KEGG: vpr:Vpar_0493 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase 1; IMG reference gene:2504585685; PFAM: GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I YP_004412665.1 COGs: COG0294 Dihydropteroate synthase; InterPro IPR006390:IPR000489; KEGG: tjr:TherJR_0210 dihydropteroate synthase; PFAM: Pterin-binding; PRIAM: Dihydropteroate synthase; SPTR: Dihydropteroate synthase; TIGRFAM: Dihydropteroate synthase; IMG reference gene:2504585686; PFAM: Pterin binding enzyme; TIGRFAM: dihydropteroate synthase YP_004412666.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006156:IPR006157; KEGG: krh:KRH_19250 dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; PRIAM: Dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase; SPTR: Dihydroneopterin aldolase; TIGRFAM: Dihydroneopterin aldolase subgroup; Dihydroneopterin aldolase; IMG reference gene:2504585687; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004412667.1 COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: sga:GALLO_1229 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR:2-amino-4-hydroxy-6-hydroxymethyldihydropterid inediphosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; IMG reference gene:2504585688; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase YP_004412668.1 COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: bpb:bpr_I1677 GGDEF/EAL domain-containing protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; SPTR: Putative sensory box sensor/GGDEF/EAL domain protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504585689; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004412669.1 KEGG: vcj:VCD_000991 hypothetical protein; SPTR: Procyclic form-specific polypeptide A-beta; IMG reference gene:2504585690 YP_004412670.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: gmc:GY4MC1_2562 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: TlpA protein; IMG reference gene:2504585691; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412671.1 COGs: COG0489 ATPase involved in chromosome partitioning; InterPro IPR005129:IPR019591; KEGG: dhd:Dhaf_1985 nucleotide-binding protein; PFAM: ATPase-like, ParA/MinD; ArgK protein; SPTR: Nucleotide-binding protein; IMG reference gene:2504585692; PFAM: ParA/MinD ATPase like; ArgK protein YP_004412672.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cbt:CLH_3316 transcriptional regulator, MarR family; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504585693; PFAM: MarR family YP_004412673.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: apr:Apre_0701 periplasmic solute binding protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Zinc ABC transporter, periplasmic zinc-binding protein; IMG reference gene:2504585694; PFAM: Periplasmic solute binding protein family YP_004412674.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: cag:Cagg_3554 ABC transporter-like protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Iron chelate ABC transporter, ATP-binding protein; IMG reference gene:2504585695; PFAM: ABC transporter YP_004412675.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: apr:Apre_0703 ABC-3 protein; PFAM: ABC-3; SPTR: Manganese transport system membrane protein MntC; IMG reference gene:2504585696; PFAM: ABC 3 transport family YP_004412676.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: apr:Apre_0704 ABC-3 protein; PFAM: ABC-3; SPTR: Zinc ABC transporter, permease protein; IMG reference gene:2504585697; PFAM: ABC 3 transport family YP_004412677.1 InterPro IPR019613; KEGG: vpr:Vpar_1323 hypothetical protein; PFAM: Nickel transport complex, NikM subunit, transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504585698; PFAM: Nickel uptake substrate-specific transmembrane region YP_004412678.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: vpr:Vpar_1341 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family domain protein; IMG reference gene:2504585699; PFAM: MotA/TolQ/ExbB proton channel family YP_004412679.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: vpr:Vpar_1756 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504585700; PFAM: Biopolymer transport protein ExbD/TolR YP_004412680.1 InterPro IPR006260; KEGG: mfa:Mfla_1560 TonB-like protein; PFAM: TonB, C-terminal; SPTR: Putative ferric siderophore transporter, periplasmic energy transduction protein TonB; IMG reference gene:2504585701; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004412681.1 COGs: COG0672 High-affinity Fe2+/Pb2+ permease; InterPro IPR004923; KEGG: wsu:WS1566 high-affinity Fe2+/Pb2+ permease; PFAM: Iron permease FTR1; SPTR: Putative membrane protein; IMG reference gene:2504585702; PFAM: Iron permease FTR1 family; TIGRFAM: FTR1 family protein YP_004412682.1 COGs: COG3470 Uncharacterized protein probably involved in high-affinity Fe2+ transport; InterPro IPR018470; KEGG: cko:CKO_02056 hypothetical protein; PFAM: Ferrous iron transport protein, bacterial; SPTR: Putative pathogen-specific surface antigen; IMG reference gene:2504585703; PFAM: Fe2+ transport protein YP_004412683.1 COGs: COG4393 membrane protein; InterPro IPR018758; KEGG: tde:TDE1512 hypothetical protein; PFAM: Protein of unknown function DUF2318, membrane; SPTR: Putative integral membrane protein; IMG reference gene:2504585704; PFAM: Predicted membrane protein (DUF2318) YP_004412684.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: tde:TDE1514 permease domain protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Permease domain protein; IMG reference gene:2504585705; PFAM: Predicted permease YP_004412685.1 COGs: COG4591 ABC-type transport system involved in lipoprotein release permease component; InterPro IPR003838; KEGG: tde:TDE1515 permease domain protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Permease domain protein; IMG reference gene:2504585706; PFAM: Predicted permease YP_004412686.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: fnu:FN1352 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Macrolide-specific ABC-type efflux carrier MacB; IMG reference gene:2504585707; PFAM: ABC transporter YP_004412687.1 COGs: COG4939 Major membrane immunogen membrane-anchored lipoprotein; InterPro IPR007329; KEGG: fma:FMG_0930 putative lipoprotein precursor; PFAM: FMN-binding; SMART: FMN-binding; SPTR: Lipoprotein; IMG reference gene:2504585708; PFAM: FMN-binding domain YP_004412688.1 COGs: COG1477 Membrane-associated lipoprotein involved in thiamine biosynthesis; InterPro IPR003374; KEGG: ele:Elen_0693 ApbE family lipoprotein; PFAM: Thiamine synthesis ApbE/UPF0280; SPTR: Membrane-associated lipoprotein; IMG reference gene:2504585709; PFAM: ApbE family YP_004412689.1 COGs: COG5341 conserved hypothetical protein; InterPro IPR010739; KEGG: ele:Elen_0692 protein of unknown function DUF1312; PFAM: Protein of unknown function DUF1312; SPTR: Putative uncharacterized protein; IMG reference gene:2504585710; PFAM: Protein of unknown function (DUF1312) YP_004412690.1 COGs: COG4769 membrane protein; InterPro IPR010898; KEGG: cpe:CPE2104 hypothetical protein; PFAM: Heptaprenyl diphosphate synthase component I; SPTR: Putative membrane protein; IMG reference gene:2504585711; PFAM: Heptaprenyl diphosphate synthase component I YP_004412691.1 InterPro IPR013096; KEGG: ccu:Ccur_09790 cupin domain-containing protein; PFAM: Cupin 2, conserved barrel; SPTR: Cupin region protein; IMG reference gene:2504585712; PFAM: Cupin domain YP_004412692.1 COGs: COG0148 Enolase; InterPro IPR020811:IPR000941:IPR020810; KEGG: ere:EUBREC_2823 enolase; PFAM: Enolase, C-terminal; Enolase, N-terminal; PRIAM: Phosphopyruvate hydratase; SPTR: Enolase; TIGRFAM: Enolase; IMG reference gene:2504585713; PFAM: Enolase, N-terminal domain; Enolase, C-terminal TIM barrel domain; TIGRFAM: phosphopyruvate hydratase YP_004412693.1 InterPro IPR006121; KEGG: eel:EUBELI_01465 hypothetical protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Conserved domain protein; IMG reference gene:2504585714; PFAM: Heavy-metal-associated domain YP_004412694.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: mta:Moth_2263 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504585715; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004412695.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: mta:Moth_2263 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Metal dependent phosphohydrolase; IMG reference gene:2504585716; PFAM: HD domain YP_004412696.1 KEGG: ptm:GSPATT00028323001 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585717 YP_004412697.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585718 YP_004412698.1 KEGG: gtn:GTNG_2007 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585719 YP_004412699.1 KEGG: gtn:GTNG_2006 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585720 YP_004412700.1 KEGG: bwe:BcerKBAB4_0823 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585721 YP_004412701.1 InterPro IPR002934; KEGG: ere:EUBREC_0313 hypothetical protein; PFAM: Nucleotidyl transferase domain; SPTR: Putative toxin-antitoxin system, toxin component; IMG reference gene:2504585722; PFAM: Nucleotidyltransferase domain YP_004412702.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: ccv:CCV52592_1605 NADPH-flavin oxidoreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase family protein; IMG reference gene:2504585724; PFAM: Nitroreductase family YP_004412703.1 COGs: COG4679 Phage-related protein; InterPro IPR009241; KEGG: afn:Acfer_1073 protein of unknown function DUF891; PFAM: Protein of unknown function DUF891; SPTR: Toxin-antitoxin system, toxin component, RelE family; IMG reference gene:2504585725; PFAM: Phage derived protein Gp49-like (DUF891) YP_004412704.1 InterPro IPR001387; KEGG: afn:Acfer_1074 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504585726; PFAM: Helix-turn-helix YP_004412705.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: axy:AXYL_03141 ferrichrome receptor FcuA 1; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative TonB-dependent receptor; IMG reference gene:2504585727; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004412706.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: vpr:Vpar_0062 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504585728; PFAM: Periplasmic binding protein YP_004412707.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: elm:ELI_3971 hypothetical protein; PFAM: ABC transporter permease protein; SPTR: Hemin ABC transporter, permease protein; IMG reference gene:2504585729; PFAM: FecCD transport family YP_004412708.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: vpr:Vpar_1603 sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter; SPTR: Sodium:dicarboxylate symporter family protein; IMG reference gene:2504585730; PFAM: Sodium:dicarboxylate symporter family YP_004412709.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR004812:IPR011701; KEGG: bbe:BBR47_33660 drug resistance transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: TcaB protein; TIGRFAM: Drug resistance transporter Bcr/CflA subfamily; IMG reference gene:2504585731; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, Bcr/CflA subfamily YP_004412710.1 COGs: COG0318 Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II; InterPro IPR000873; KEGG: afn:Acfer_0829 AMP-dependent synthetase and ligase; PFAM: AMP-dependent synthetase/ligase; PRIAM: o-succinylbenzoate--CoA ligase; SPTR: CoA ligase; IMG reference gene:2504585732; PFAM: AMP-binding enzyme; TIGRFAM: O-succinylbenzoate-CoA ligase YP_004412711.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: scb:SCAB_63951 solute-binding protein; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Periplasmic ribose-binding protein; IMG reference gene:2504585733; PFAM: family YP_004412712.1 KEGG: cki:Calkr_0678 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585734 YP_004412713.1 InterPro IPR022453; KEGG: ckl:CKL_0470 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Zinc finger, YgiT-type; IMG reference gene:2504585735; TIGRFAM: YgiT-type zinc finger domain YP_004412714.1 InterPro IPR004692; KEGG: vpr:Vpar_1010 preprotein translocase, SecG subunit; PFAM: Preprotein translocase SecG subunit; SPTR: Preprotein translocase, SecG subunit; TIGRFAM: Preprotein translocase SecG subunit; IMG reference gene:2504585736; PFAM: Preprotein translocase SecG subunit; TIGRFAM: protein translocase, SecG subunit YP_004412715.1 COGs: COG1647 Esterase/lipase; InterPro IPR002925; KEGG: afn:Acfer_0972 alpha/beta hydrolase fold protein; PFAM: Dienelactone hydrolase; PRIAM: Carboxylesterase; SPTR: Putative carboxylesterase; IMG reference gene:2504585737; PFAM: Dienelactone hydrolase family YP_004412716.1 InterPro IPR006683; KEGG: dau:Daud_0327 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family protein; IMG reference gene:2504585738; PFAM: Thioesterase superfamily YP_004412717.1 COGs: COG0557 Exoribonuclease R; InterProIPR011805:IPR001900:IPR003029:IPR022967:IPR 013223:IPR011129:IPR004476; KEGG: afn:Acfer_0974 ribonuclease R; PFAM: Ribonuclease II/R; Ribosomal protein S1, RNA-binding domain; Ribonuclease B, N-terminal OB domain; PRIAM: Exoribonuclease II; SMART: Ribonuclease II/R; RNA-binding domain, S1; Cold shock protein; SPTR: Ribonuclease R; TIGRFAM: Ribonuclease R, bacterial; Ribonuclease II/ribonuclease R, bacteria; IMG reference gene:2504585739; PFAM: RNB domain; Ribonuclease B OB domain; S1 RNA binding domain; TIGRFAM: ribonuclease R; VacB and RNase II family 3'-5' exoribonucleases YP_004412718.1 COGs: COG0691 tmRNA-binding protein; InterPro IPR000037; KEGG: bae:BATR1942_14765 SsrA-binding protein; PFAM: SsrA-binding protein; SPTR: SsrA-binding protein; TIGRFAM: SsrA-binding protein; IMG reference gene:2504585740; PFAM: SmpB protein; TIGRFAM: SsrA-binding protein YP_004412719.1 InterPro IPR007712; KEGG: gct:GC56T3_3131 plasmid stabilization system; PFAM: Plasmid stabilisation system; SPTR: Toxin-antitoxin system, toxin component, RelE family; IMG reference gene:2504585741 YP_004412720.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585742 YP_004412721.1 InterPro IPR001845; KEGG: aoe:Clos_0896 ArsR family transcriptional regulator; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional repressor PagR; IMG reference gene:2504585743; PFAM: Bacterial regulatory protein, arsR family YP_004412722.1 COGs: COG3467 flavin-nucleotide-binding protein; InterPro IPR011576; KEGG: cbi:CLJ_B0881 5-nitroimidazole resistance protein NimA; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: 5-nitroimidazole resistance protein NimA; IMG reference gene:2504585745; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004412723.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: amt:Amet_0616 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: Putative Na+ driven multidrug efflux pump; IMG reference gene:2504585746; PFAM: MatE YP_004412724.1 InterPro IPR000064; KEGG: afn:Acfer_1665 NLP/P60 protein; PFAM: NLP/P60; SPTR: NlpC/P60 family protein; IMG reference gene:2504585747; PFAM: NlpC/P60 family YP_004412725.1 COGs: COG4295 conserved hypothetical protein; InterPro IPR019261; KEGG: fsu:Fisuc_1152 protein of unknown function DUF2263; PFAM: Protein of unknown function DUF2263; SPTR: Putative uncharacterized protein; IMG reference gene:2504585749; PFAM: Uncharacterized protein conserved in bacteria (DUF2263); TIGRFAM: TIGR02452 family protein YP_004412726.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585750 YP_004412727.1 InterPro IPR002145; KEGG: llc:LACR_C29 hypothetical protein; PFAM: CopG-like DNA-binding; SPTR: Ribbon-helix-helix protein, CopG family; IMG reference gene:2504585751; PFAM: Ribbon-helix-helix protein, copG family YP_004412728.1 InterPro IPR021215; KEGG: tcu:Tcur_2876 putative transmembrane protein; PFAM: Protein of unknown function DUF2752; SPTR: Putative membrane protein; IMG reference gene:2504585752; PFAM: Protein of unknown function (DUF2752) YP_004412729.1 KEGG: cth:Cthe_0307 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585753 YP_004412730.1 KEGG: bpb:bpr_I0018 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585754 YP_004412731.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: adg:Adeg_1282 protein of unknown function DUF322; PFAM: Alkaline shock protein Asp23; SPTR: Gls24 protein; IMG reference gene:2504585755; PFAM: Protein of unknown function (DUF322) YP_004412732.1 COGs: COG2367 Beta-lactamase class A; KEGG: afn:Acfer_0879 beta-lactamase class A-like protein; SPTR: Beta-lactamase; IMG reference gene:2504585756; PFAM: D-alanyl-D-alanine carboxypeptidase YP_004412733.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: dsy:DSY4849 hypothetical protein; PFAM: Polysaccharide deacetylase; SPTR: Peptidoglycan N-acetylglucosamine deacetylase A; IMG reference gene:2504585757; PFAM: Polysaccharide deacetylase YP_004412734.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004839:IPR005861; KEGG: eel:EUBELI_00629 histidinol-phosphate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: Histidinol-phosphate transaminase; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: Histidinol-phosphate aminotransferase; IMG reference gene:2504585758; PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase YP_004412735.1 KEGG: str:Sterm_1305 protein of unknown function DUF1121; SPTR: Putative uncharacterized protein; IMG reference gene:2504585759; PFAM: Uncharacterised ACR, YkgG family COG1556 YP_004412736.1 COGs: COG1472 Beta-glucosidase-related glycosidase; InterPro IPR001764; KEGG: vpr:Vpar_1773 glycoside hydrolase family 3 domain protein; PFAM: Glycoside hydrolase, family 3, N-terminal; SPTR: Beta-hexosaminidase; IMG reference gene:2504585760; PFAM: Glycosyl hydrolase family 3 N terminal domain YP_004412737.1 KEGG: ere:EUBREC_1021 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585761; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004412738.1 KEGG: afn:Acfer_2052 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585762 YP_004412739.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027; KEGG: cpy:Cphy_1503 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: Thioredoxin-disulfide reductase; SPTR: Thioredoxin-disulfide reductase; IMG reference gene:2504585763; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004412740.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013702:IPR004089:IPR019494; KEGG: sdl:Sdel_0982 domain of unknown function DUF1745; PFAM: FIST C domain; FIST domain, N-terminal; Chemotaxis methyl-accepting receptor, signalling; SMART: FIST domain, N-terminal; Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative mcp-domain signal transduction protein; IMG reference gene:2504585764; PFAM: FIST C domain; Methyl-accepting chemotaxis protein (MCP) signaling domain; FIST N domain YP_004412741.1 COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: afn:Acfer_1854 AzlC family protein; PFAM: Branched-chain amino acid transport, permease; SPTR: Branched-chain amino acid transport protein AzlC; IMG reference gene:2504585765; PFAM: AzlC protein; TIGRFAM: 4-azaleucine resistance probable transporter AzlC YP_004412742.1 COGs: COG1687 branched-chain amino acid permease (azaleucine resistance); InterPro IPR008407; KEGG: afn:Acfer_1855 branched-chain amino acid transport; PFAM: Branched-chain amino acid transport, AzlD; SPTR: Branched-chain amino acid transport protein AzlD; IMG reference gene:2504585766; PFAM: Branched-chain amino acid transport protein (AzlD) YP_004412743.1 COGs: COG3118 Thioredoxin domain-containing protein; InterPro IPR005746:IPR013766; KEGG: csh:Closa_4027 thioredoxin; PFAM: Thioredoxin domain; SPTR: Thioredoxin; TIGRFAM: Thioredoxin; IMG reference gene:2504585767; PFAM: Thioredoxin; TIGRFAM: thioredoxin YP_004412744.1 COGs: COG0288 Carbonic anhydrase; InterPro IPR001765; KEGG: vpr:Vpar_1311 carbonic anhydrase; PFAM: Carbonic anhydrase; PRIAM: Carbonate dehydratase; SMART: Carbonic anhydrase; SPTR: Carbonate dehydratase; IMG reference gene:2504585768; PFAM: Carbonic anhydrase YP_004412745.1 COGs: COG4720 membrane protein; InterPro IPR009825; KEGG: eel:EUBELI_20609 hypothetical protein; PFAM: Protein of unknown function DUF1393; SPTR: Putative membrane spanning protein; IMG reference gene:2504585769; PFAM: Protein of unknown function (DUF1393) YP_004412746.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR022432:IPR020050:IPR006638:IPR007197; KEGG: slp:Slip_1167 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Menaquinone biosynthesis protein, SCO4494 family; TIGRFAM: Menaquinone biosynthesis, SCO4494, predicted; FO synthase, subunit 2; IMG reference gene:2504585770; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily YP_004412747.1 KEGG: dae:Dtox_0466 hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, PHD family; IMG reference gene:2504585772; PFAM: Phd_YefM YP_004412748.1 COGs: COG1393 Arsenate reductase and related protein glutaredoxin family; InterPro IPR006504:IPR006660; KEGG: cth:Cthe_1508 hypothetical protein; PFAM: Arsenate reductase-like; SPTR: ArsC family protein; TIGRFAM: Transcriptional regulator Spx/MgsR; IMG reference gene:2504585773; PFAM: ArsC family; TIGRFAM: transcriptional regulator, Spx/MgsR family YP_004412749.1 KEGG: hor:Hore_17170 flagellar protein; SPTR: Flagellar protein; IMG reference gene:2504585774 YP_004412750.1 InterPro IPR007412; PFAM: Anti-sigma-28 factor, FlgM; SPTR: Negative regulator of flagellin synthesis FlgM; IMG reference gene:2504585775; PFAM: Anti-sigma-28 factor, FlgM YP_004412751.1 InterPro IPR007809; PFAM: FlgN-like domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504585776; PFAM: FlgN protein YP_004412752.1 InterPro IPR007809; KEGG: toc:Toce_1598 FlgN family protein; PFAM: FlgN-like domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504585777; PFAM: FlgN protein YP_004412753.1 COGs: COG1256 Flagellar hook-associated protein; InterPro IPR010930:IPR002371; KEGG: adg:Adeg_0248 flagellar hook-associated protein FlgK; PFAM: Domain of unknown function DUF1078, C-terminal; SPTR: Flagellar hook-associated protein FlgK; TIGRFAM: Flagellar hook-associated protein, FlgK; IMG reference gene:2504585778; PFAM: Domain of unknown function (DUF1078); TIGRFAM: flagellar hook-associated protein FlgK YP_004412754.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001029:IPR013384; KEGG: aoe:Clos_2520 flagellar hook-associated protein 3; PFAM: Flagellin, D0/D1 domain; SPTR: Flagellar hook-associated protein 3; TIGRFAM: Flagellar hook-associated protein 3; IMG reference gene:2504585779; PFAM: Bacterial flagellin N-terminal helical region; TIGRFAM: flagellar hook-associated protein 3 YP_004412755.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585780 YP_004412756.1 COGs: COG1699 conserved hypothetical protein; InterPro IPR003775; KEGG: swo:Swol_0195 hypothetical protein; PFAM: Flagellar assembly factor FliW; SPTR: Flagellar assembly factor fliW; IMG reference gene:2504585781; PFAM: FliW protein YP_004412757.1 COGs: COG1551 Carbon storage regulator (could also regulate swarming and quorum sensing); InterPro IPR003751; KEGG: dsy:DSY3024 hypothetical protein; PFAM: Carbon storage regulator; SPTR: Carbon storage regulator homolog; TIGRFAM: Carbon storage regulator; IMG reference gene:2504585782; PFAM: Global regulator protein family; TIGRFAM: carbon storage regulator (csrA) YP_004412758.1 COGs: COG1334 Uncharacterized flagellar protein FlaG; InterPro IPR005186; KEGG: aae:aq_2000 hypothetical protein; PFAM: Flagellar protein FlaG protein; SPTR: FlaG protein; IMG reference gene:2504585783; PFAM: FlaG protein YP_004412759.1 COGs: COG1345 Flagellar capping protein; InterPro IPR010809:IPR003481; KEGG: hmo:HM1_1211 flagellar hook-associated protein 2; PFAM: Flagellar hook-associated 2, C-terminal; Flagellar hook-associated protein 2, N-terminal; SPTR: Putative flagellar hook-associated protein 2; IMG reference gene:2504585784; PFAM: Flagellar hook-associated protein 2 C-terminus YP_004412760.1 COGs: COG1516 Flagellin-specific chaperone FliS; InterPro IPR003713; KEGG: cth:Cthe_2217 flagellar protein FliS; PFAM: Flagellar protein FliS; SPTR: Flagellar protein FliS; TIGRFAM: Flagellar protein FliS; IMG reference gene:2504585785; PFAM: Flagellar protein FliS; TIGRFAM: flagellar biosynthetic protein FliS YP_004412761.1 KEGG: dhd:Dhaf_4162 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585786 YP_004412762.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001029; KEGG: hmo:HM1_1250 flagellin protein; PFAM: Flagellin, D0/D1 domain; SPTR: Flagellin; IMG reference gene:2504585787; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region YP_004412763.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: dsy:DSY3021 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Putative glycosyltransferase; IMG reference gene:2504585788; PFAM: Glycosyl transferase family 2 YP_004412764.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: clj:CLJU_c09640 putative glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyltransferase; IMG reference gene:2504585789; PFAM: Glycosyl transferase family 2 YP_004412765.1 COGs: COG3914 O-linked N-acetylglucosamine transferase SPINDLY family; InterPro IPR019734; KEGG: glo:Glov_2093 TPR repeat-containing protein; SPTR: Putative tetratricopeptide repeat-containing domain protein; IMG reference gene:2504585790 YP_004412766.1 COGs: COG3914 O-linked N-acetylglucosamine transferase SPINDLY family; KEGG: gem:GM21_3825 tetratricopeptide TPR_2 repeat protein; SPTR: Putative UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SPINDLY; IMG reference gene:2504585791 YP_004412767.1 SPTR: Putative tetratricopeptide repeat-containing domain protein; IMG reference gene:2504585792 YP_004412768.1 KEGG: met:M446_3121 O-methyltransferase; SPTR: O-methyltransferase I; IMG reference gene:2504585793; PFAM: Cephalosporin hydroxylase YP_004412769.1 InterPro IPR001173; KEGG: mch:Mchl_3179 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Putative uncharacterized protein; IMG reference gene:2504585794 YP_004412770.1 COGs: COG4750 CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes; InterPro IPR005835; KEGG: ele:Elen_2028 CTP:phosphocholine cytidylyltransferase-like protein; PFAM: Nucleotidyl transferase; SPTR: Putative choline kinase; IMG reference gene:2504585795; PFAM: Nucleotidyl transferase YP_004412771.1 COGs: COG2513 PEP phosphonomutase; InterPro IPR004821:IPR004820:IPR012698; KEGG: ols:Olsu_0594 phosphoenolpyruvate phosphomutase; PFAM: Cytidylyltransferase; PRIAM: Phosphoenolpyruvate mutase; SPTR: Phosphoenolpyruvate mutase; TIGRFAM: Phosphoenolpyruvate phosphomutase, core; Cytidyltransferase-related; IMG reference gene:2504585796; PFAM: Cytidylyltransferase; TIGRFAM: phosphoenolpyruvate phosphomutase; cytidyltransferase-related domain YP_004412772.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: cdf:CD0212 putative choline sulfatase; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585797; PFAM: Sulfatase YP_004412773.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: cdf:CD0212 putative choline sulfatase; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585798; PFAM: Sulfatase YP_004412774.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ppy:PPE_04397 hypothetical protein; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585799; PFAM: Sulfatase YP_004412775.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ppy:PPE_04397 hypothetical protein; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585800; PFAM: Sulfatase YP_004412776.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: cbb:CLD_1848 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504585801; PFAM: Glycosyl transferase family 2 YP_004412777.1 COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: elm:ELI_2397 lipopolysaccharide biosynthesis protein RfbH; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: Lipopolysaccharide biosynthesis protein RfbH; IMG reference gene:2504585802; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family YP_004412778.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: mpt:Mpe_A2764 lipopolysaccharide heptosyltransferase-1, putative; PFAM: Glycosyl transferase, family 9; SPTR: Heptosyltransferase family protein; IMG reference gene:2504585803; PFAM: Glycosyltransferase family 9 (heptosyltransferase) YP_004412779.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585804 YP_004412780.1 KEGG: chy:CHY_0980 glycosyl transferase family protein; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504585805 YP_004412781.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR013445; KEGG: csh:Closa_0495 CDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: CDP-glucose 4,6-dehydratase; SPTR: CDP-glucose 4,6-dehydratase; TIGRFAM: CDP-glucose 4,6-dehydratase; IMG reference gene:2504585806; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: CDP-glucose 4,6-dehydratase YP_004412782.1 InterPro IPR005358; KEGG: slp:Slip_1896 hypothetical protein; PFAM: Uncharacterised protein family UPF0153; SPTR: FliB family protein; IMG reference gene:2504585807 YP_004412783.1 InterPro IPR013344:IPR000788; KEGG: ipo:Ilyop_1136 ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; PFAM: Ribonucleotide reductase large subunit, C-terminal; PRIAM: Ribonucleoside-diphosphate reductase; SPTR: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; TIGRFAM: Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; IMG reference gene:2504585808; PFAM: Ribonucleotide reductase, barrel domain; TIGRFAM: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent YP_004412784.1 COGs: COG1742 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0060; InterPro IPR003844; KEGG: cbe:Cbei_2176 hypothetical protein; PFAM: Uncharacterised protein family UPF0060; SPTR: UPF0060 membrane protein SELSPUOL_02349; IMG reference gene:2504585809; PFAM: Uncharacterised BCR, YnfA/UPF0060 family YP_004412785.1 InterPro IPR005546:IPR006315; KEGG: dvm:DvMF_1880 outer membrane autotransporter barrel domain protein; SMART: Autotransporter beta-domain; SPTR: Putative outer membrane autotransporter barrel domain protein; TIGRFAM: Outer membrane autotransporter barrel; IMG reference gene:2504585810 YP_004412786.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: afn:Acfer_0288 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Membrane bound protein LytR; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504585811; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004412787.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: vpr:Vpar_0662 ABC transporter related protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter domain protein; IMG reference gene:2504585812; PFAM: ABC transporter YP_004412788.1 COGs: COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member; InterPro IPR003583:IPR000606:IPR003593:IPR006345; KEGG: afn:Acfer_1467 helicase, RecD/TraA family; PFAM: Helicase domain, viral-like; PRIAM: Exodeoxyribonuclease V; SMART: ATPase, AAA+ type, core; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Helicase, RecD/TraA family; TIGRFAM: DNA helicase, RecD/TraA type; IMG reference gene:2504585813; PFAM: Viral (Superfamily 1) RNA helicase; TIGRFAM: helicase, putative, RecD/TraA family YP_004412789.1 COGs: COG1040 amidophosphoribosyltransferase; InterPro IPR000836; KEGG: dra:DR_1389 competence protein ComF, putative; PFAM: Phosphoribosyltransferase; SPTR: Competence protein F; IMG reference gene:2504585814; PFAM: Phosphoribosyl transferase domain; TIGRFAM: comF family protein YP_004412790.1 COGs: COG0441 Threonyl-tRNA synthetase; InterPro IPR012947:IPR002320:IPR002314:IPR004154; KEGG: tro:trd_1067 threonyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Threonyl/alanyl tRNA synthetase, SAD; Anticodon-binding; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Threonyl-tRNA synthetase; TIGRFAM: Threonyl-tRNA synthetase, class IIa; IMG reference gene:2504585815; PFAM: Anticodon binding domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: threonyl-tRNA synthetase YP_004412791.1 InterPro IPR012650:IPR004260; KEGG: lba:Lebu_1626 hypothetical protein; PFAM: Pyrimidine dimer DNA glycosylase; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP02328; IMG reference gene:2504585817; PFAM: Pyrimidine dimer DNA glycosylase; TIGRFAM: conserved hypothetical protein YP_004412792.1 COGs: COG0001 Glutamate-1-semialdehyde aminotransferase; InterPro IPR004639:IPR005814; KEGG: mta:Moth_1244 glutamate-1-semialdehyde 2,1-aminomutase; PFAM: Aminotransferase class-III; PRIAM: Glutamate-1-semialdehyde 2,1-aminomutase; SPTR: Glutamate-1-semialdehyde-2,1-aminomutase; TIGRFAM: Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase; IMG reference gene:2504585818; PFAM: Aminotransferase class-III; TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase YP_004412793.1 COGs: COG0113 Delta-aminolevulinic acid dehydratase; InterPro IPR001731; KEGG: vpr:Vpar_1423 delta-aminolevulinic acid dehydratase; PFAM: Tetrapyrrole biosynthesis, porphobilinogen synthase; PRIAM: Porphobilinogen synthase; SPTR: Delta-aminolevulinic acid dehydratase; IMG reference gene:2504585819; PFAM: Delta-aminolevulinic acid dehydratase YP_004412794.1 COGs: COG0007 Uroporphyrinogen-III methylase; InterPro IPR003754:IPR006366:IPR000878; KEGG: pth:PTH_0973 uroporphyrinogen-III methylase and uroporphyrinogen-III synthase; PFAM: Tetrapyrrole biosynthesis, uroporphyrinogen III synthase; Tetrapyrrole methylase; PRIAM: Uroporphyrinogen-III C-methyltransferase., Uroporphyrinogen-III synthase; SPTR: Uroporphyrinogen III synthase/methyltransferase; TIGRFAM: Uroporphyrin-III C-methyltransferase, C-terminal; IMG reference gene:2504585820; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; Uroporphyrinogen-III synthase HemD; TIGRFAM: uroporphyrin-III C-methyltransferase YP_004412795.1 COGs: COG0181 Porphobilinogen deaminase; HAMAP: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; InterPro IPR000860:IPR022417:IPR022418; KEGG: gsu:GSU3285 porphobilinogen deaminase; PFAM: Porphobilinogen deaminase, N-terminal; Porphobilinogen deaminase, C-terminal domain; SPTR: Hydroxymethylbilane synthase; TIGRFAM: Tetrapyrrole biosynthesis, hydroxymethylbilane synthase; IMG reference gene:2504585821; PFAM: Porphobilinogen deaminase, C-terminal domain; Porphobilinogen deaminase, dipyromethane cofactor binding domain; TIGRFAM: porphobilinogen deaminase YP_004412796.1 COGs: COG0373 Glutamyl-tRNA reductase; InterPro IPR015895:IPR015896:IPR000343:IPR006151; KEGG: vpr:Vpar_1426 glutamyl-tRNA reductase; PFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal; Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Glutamyl-tRNA reductase; TIGRFAM: Tetrapyrrole biosynthesis, glutamyl-tRNA reductase; IMG reference gene:2504585822; PFAM: Shikimate / quinate 5-dehydrogenase; Glutamyl-tRNAGlu reductase, N-terminal domain; Glutamyl-tRNAGlu reductase, dimerisation domain; TIGRFAM: glutamyl-tRNA reductase YP_004412797.1 COGs: COG1648 Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain); InterPro IPR006367:IPR019478; KEGG: adg:Adeg_1261 siroheme synthase; PFAM: Sirohaem synthase, dimerisation domain; SPTR: Siroheme synthase; TIGRFAM: Sirohaem synthase, N-terminal; IMG reference gene:2504585823; PFAM: Sirohaem synthase dimerisation region; TIGRFAM: siroheme synthase, N-terminal domain YP_004412798.1 COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR006096:IPR006097; KEGG: cpf:CPF_1770 glutamate dehydrogenase; PFAM: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain; PRIAM: Glutamate dehydrogenase (NADP(+)); SMART: Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal; SPTR: Glutamate dehydrogenase, NADP-specific; IMG reference gene:2504585824; PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain YP_004412799.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585825 YP_004412800.1 COGs: COG0253 Diaminopimelate epimerase; InterPro IPR001653; KEGG: mta:Moth_0888 diaminopimelate epimerase; PFAM: Diaminopimelate epimerase; PRIAM: Diaminopimelate epimerase; SPTR: Diaminopimelate epimerase; TIGRFAM: Diaminopimelate epimerase; IMG reference gene:2504585826; PFAM: Diaminopimelate epimerase; TIGRFAM: diaminopimelate epimerase YP_004412801.1 KEGG: tde:TDE0948 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585827; PFAM: Putative transposase, YhgA-like YP_004412802.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: afn:Acfer_0613 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Purine transporter, AzgA family; IMG reference gene:2504585828; PFAM: Permease family YP_004412803.1 COGs: COG3189 conserved hypothetical protein; InterPro IPR007438; KEGG: tva:TVAG_003130 hypothetical protein; PFAM: Protein of unknown function DUF488; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504585829; PFAM: Protein of unknown function, DUF488 YP_004412804.1 COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: bad:BAD_0527 low specificity-threonine aldolase; PFAM: Aromatic amino acid beta-eliminating lyase/threonine aldolase; SPTR: Low specificity L-threonine aldolase; IMG reference gene:2504585830; PFAM: Beta-eliminating lyase YP_004412805.1 InterPro IPR011576; KEGG: bpb:bpr_I2719 pyridoxamine 5'-phosphate oxidase family protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Pyridoxamine 5'-phosphate oxidase family protein; IMG reference gene:2504585831; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004412806.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: hmo:HM1_0231 2-nitropropane dioxygenase; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Enoyl-(Acyl-carrier-protein) reductase II; IMG reference gene:2504585833; PFAM: 2-nitropropane dioxygenase; TIGRFAM: putative enoyl-(acyl-carrier-protein) reductase II YP_004412807.1 COGs: COG4679 Phage-related protein; InterPro IPR009241; KEGG: bpb:bpr_I0707 hypothetical protein; PFAM: Protein of unknown function DUF891; SPTR: Toxin-antitoxin system, toxin component, RelE family; manually curated; IMG reference gene:2504585834; PFAM: Phage derived protein Gp49-like (DUF891) YP_004412808.1 COGs: COG4463 Transcriptional repressor of class III stress genes; InterPro IPR008463; KEGG: ppm:PPSC2_c4814 transcriptional repressor; PFAM: Firmicute transcriptional repressor of class III stress genes; SPTR: Transcriptional regulator CtsR; IMG reference gene:2504585835; PFAM: Firmicute transcriptional repressor of class III stress genes (CtsR) YP_004412809.1 COGs: COG3880 Uncharacterized protein with conserved CXXC pairs; InterPro IPR001943; KEGG: tmt:Tmath_1959 UvrB/UvrC protein; PFAM: UvrB/UvrC protein; SPTR: Modulator of CtsR repression McsA; IMG reference gene:2504585836; PFAM: UvrB/uvrC motif YP_004412810.1 COGs: COG3869 Arginine kinase; InterPro IPR022414; KEGG: gym:GYMC10_5781 ATP:guanido phosphotransferase; PFAM: ATP:guanido phosphotransferase, catalytic domain; SPTR: ATP:guanido phosphotransferase domain protein; IMG reference gene:2504585837; PFAM: ATP:guanido phosphotransferase, C-terminal catalytic domain YP_004412811.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR003959:IPR001943:IPR013093:IPR003593:IPR 004176:IPR019489; KEGG: adg:Adeg_1948 ATPase AAA-2 domain protein; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; UvrB/UvrC protein; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Negative regulator of genetic competence ClpC/MecB; IMG reference gene:2504585838; PFAM: AAA domain (Cdc48 subfamily); Clp amino terminal domain; C-terminal, D2-small domain, of ClpB protein; ATPase family associated with various cellular activities (AAA); UvrB/uvrC motif YP_004412812.1 IMG reference gene:2504585839 YP_004412813.1 COGs: COG1066 ATP-dependent serine protease; InterPro IPR003593:IPR004504; KEGG: sth:STH3128 DNA repair protein RadA; SMART: ATPase, AAA+ type, core; SPTR: DNA repair protein radA; TIGRFAM: DNA repair protein RadA; IMG reference gene:2504585840; PFAM: KaiC; Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: DNA repair protein RadA YP_004412814.1 COGs: COG1115 Na+/alanine symporter; InterPro IPR001463; KEGG: hmo:HM1_1545 sodium:alanine symporter; PFAM: Sodium:alanine symporter; SPTR: Amino acid carrier protein; TIGRFAM: Sodium:alanine symporter; IMG reference gene:2504585841; PFAM: Sodium:alanine symporter family; TIGRFAM: amino acid carrier protein YP_004412815.1 COGs: COG0853 Aspartate 1-decarboxylase; InterPro IPR003190; KEGG: pth:PTH_0222 aspartate alpha-decarboxylase; PFAM: Aspartate decarboxylase; PRIAM: Aspartate 1-decarboxylase; SPTR: Aspartate 1-decarboxylase; TIGRFAM: Aspartate decarboxylase; IMG reference gene:2504585842; PFAM: Aspartate decarboxylase; TIGRFAM: L-aspartate-alpha-decarboxylase YP_004412816.1 COGs: COG0414 Panthothenate synthetase; InterPro IPR003721:IPR004821; KEGG: pth:PTH_0221 pantoate--beta-alanine ligase; PFAM: Pantoate-beta-alanine ligase; SPTR: Pantothenate synthetase; TIGRFAM: Pantoate-beta-alanine ligase; Cytidyltransferase-related; IMG reference gene:2504585843; PFAM: Pantoate-beta-alanine ligase; TIGRFAM: pantoate--beta-alanine ligase; cytidyltransferase-related domain YP_004412817.1 COGs: COG0385 Na+-dependent transporter; InterPro IPR002657; KEGG: afn:Acfer_0775 bile acid:sodium symporter; PFAM: Bile acid:sodium symporter; SPTR: Sodium/bile acid transporter family protein; IMG reference gene:2504585844; PFAM: Sodium Bile acid symporter family; TIGRFAM: bile acid transporter YP_004412818.1 KEGG: vpr:Vpar_0646 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585845 YP_004412819.1 KEGG: afn:Acfer_1656 hypothetical protein; SPTR: Putative Tat pathway protein; IMG reference gene:2504585846 YP_004412820.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611; KEGG: aar:Acear_0222 PfkB domain protein; PFAM: Carbohydrate/purine kinase; SPTR: D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenosyltransferase; IMG reference gene:2504585847; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I YP_004412821.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR004821:IPR004820:IPR011914; KEGG: fnu:FN0930 glycerol-3-phosphate cytidylyltransferase; PFAM: Cytidylyltransferase; SPTR: Protein RfaE, domain II; TIGRFAM: RfaE bifunctional protein, domain II; Cytidyltransferase-related; IMG reference gene:2504585848; PFAM: Cytidylyltransferase; TIGRFAM: rfaE bifunctional protein, domain II; cytidyltransferase-related domain YP_004412822.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: hor:Hore_18890 3-deoxy-D-manno-octulosonic-acid transferase domain protein; PFAM: Glycosyl transferase, family 9; SPTR: Putative lipopolysaccharide heptosyltransferase-1; IMG reference gene:2504585849; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase I; lipopolysaccharide heptosyltransferase II YP_004412823.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: afn:Acfer_1650 glycosyl transferase family 9; PFAM: Glycosyl transferase, family 9; SPTR: Heptosyltransferase family protein; IMG reference gene:2504585850; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II YP_004412824.1 COGs: COG2870 ADP-heptose synthase bifunctional sugar kinase/adenylyltransferase; InterPro IPR011611:IPR011913; KEGG: afn:Acfer_1654 RfaE bifunctional protein; PFAM: Carbohydrate/purine kinase; SPTR: Protein RfaE, domain I; TIGRFAM: RfaE bifunctional protein, domain I; IMG reference gene:2504585851; PFAM: pfkB family carbohydrate kinase; TIGRFAM: rfaE bifunctional protein, domain I YP_004412825.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; HAMAP: ADP-L-glycero-D-manno-heptose-6-epimerase; InterPro IPR011912:IPR001509; KEGG: vpr:Vpar_0757 ADP-L-glycero-D-manno-heptose-6-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: ADP-glyceromanno-heptose 6-epimerase; SPTR: ADP-glyceromanno-heptose 6-epimerase; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase; IMG reference gene:2504585852; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: ADP-L-glycero-D-manno-heptose-6-epimerase YP_004412826.1 COGs: COG0241 Histidinol phosphatase and related phosphatase; InterPro IPR006543:IPR013954:IPR006549; KEGG: dma:DMR_02160 D,D-heptose 1,7-bisphosphate phosphatase; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpA; TIGRFAM: HAD-superfamily hydrolase, subfamily IIIA; Histidinol-phosphate phosphatase; IMG reference gene:2504585853; PFAM: Polynucleotide kinase 3 phosphatase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; HAD-superfamily hydrolase, subfamily IIIA; D,D-heptose 1,7-bisphosphate phosphatase; histidinol-phosphate phosphatase family domain YP_004412827.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: vfi:VF_0149 glycosyltransferase; PFAM: Glycosyl transferase, group 1; SPTR: Putative glycosyl transferase, group 1; IMG reference gene:2504585854; PFAM: Glycosyl transferases group 1 YP_004412828.1 COGs: COG4641 conserved hypothetical protein; KEGG: gym:GYMC10_1460 hypothetical protein; SPTR: Maturation of the outermost layer of the spore; IMG reference gene:2504585855 YP_004412829.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: pay:PAU_04357 putative LPS biosynthesis enzyme (lipopolysaccharide core biosynthesi protein rfaq); PFAM: Glycosyl transferase, family 9; SPTR: Putative ADP-heptose--LPS heptosyltransferase II; IMG reference gene:2504585856; PFAM: Glycosyltransferase family 9 (heptosyltransferase) YP_004412830.1 KEGG: tbd:Tbd_1883 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585857 YP_004412831.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585858 YP_004412832.1 COGs: COG1368 Phosphoglycerol transferase and related protein alkaline phosphatase superfamily; InterPro IPR000917; KEGG: vpr:Vpar_0015 sulfatase; PFAM: Sulfatase; SPTR: Putative arylsulfatase; IMG reference gene:2504585859; PFAM: Sulfatase YP_004412833.1 KEGG: bba:Bd1672 putative N-acetylglucosaminyltransferase; SPTR: Beta-1,4-N-acetylglucosaminyltransferase; IMG reference gene:2504585860; PFAM: Glycosyltransferase family 17 YP_004412834.1 COGs: COG2990 conserved hypothetical protein; InterPro IPR007488; KEGG: afn:Acfer_1658 protein of unknown function DUF535; PFAM: Protein of unknown function DUF535; SPTR: Putative uncharacterized protein; IMG reference gene:2504585861; PFAM: Protein of unknown function (DUF535) YP_004412835.1 COGs: COG4637 ATPase; InterPro IPR003395; KEGG: dak:DaAHT2_2162 SMC domain protein; PFAM: RecF/RecN/SMC; SPTR: Putative RecF/RecN/SMC N domain protein; IMG reference gene:2504585862 YP_004412836.1 KEGG: plu:plu3301 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585863 YP_004412837.1 InterPro IPR010235; KEGG: afn:Acfer_0872 nucleotidyltransferase substrate binding protein, HI0074 family; PFAM: Nucleotidyltransferase substrate binding protein, HI0074; SPTR: Putative toxin-antitoxin system, antitoxin component; TIGRFAM: Nucleotidyltransferase substrate binding protein, HI0074; manually curated; IMG reference gene:2504585864; PFAM: Nucleotidyltransferase substrate binding protein like; TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family YP_004412838.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: cjk:jk0129 putative DNA-binding protein; PFAM: ATPase, AAA-4; SPTR: Putative DNA-binding protein; IMG reference gene:2504585865; PFAM: Divergent AAA domain YP_004412839.1 InterPro IPR002934; KEGG: ere:EUBREC_2415 putative nucleotidyltransferase; PFAM: Nucleotidyl transferase domain; SPTR: Putative toxin-antitoxin system, toxin component; manually curated; IMG reference gene:2504585866; PFAM: Nucleotidyltransferase domain YP_004412840.1 InterPro IPR010235; KEGG: ere:EUBREC_2414 nucleotidyltransferase; PFAM: Nucleotidyltransferase substrate binding protein, HI0074; SPTR: Putative toxin-antitoxin system, antitoxin component; TIGRFAM: Nucleotidyltransferase substrate binding protein, HI0074; manually curated; IMG reference gene:2504585867; PFAM: Nucleotidyltransferase substrate binding protein like; TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family YP_004412841.1 COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: ele:Elen_3019 filamentation induced by cAMP protein Fic; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Putative bacterial regulatory protein; IMG reference gene:2504585868; PFAM: Fic/DOC family YP_004412842.1 COGs: COG1853 Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family; KEGG: cdl:CDR20291_2028 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585869; PFAM: Flavin reductase like domain YP_004412843.1 COGs: COG0664 cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinase; InterPro IPR000595; KEGG: dds:Ddes_1827 transcriptional regulator, Crp/Fnr family; PFAM: Cyclic nucleotide-binding domain; SMART: Cyclic nucleotide-binding domain; SPTR: Cyclic nucleotide binding domain protein; IMG reference gene:2504585870; PFAM: Cyclic nucleotide-binding domain YP_004412844.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: dae:Dtox_3120 citrate transporter; PFAM: Divalent ion symporter; SPTR: Arsenic transporter family protein; IMG reference gene:2504585871; PFAM: Citrate transporter YP_004412845.1 KEGG: ere:EUBREC_2192 hypothetical protein; SPTR: Transposase; IMG reference gene:2504585872; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004412846.1 KEGG: afn:Acfer_1831 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585873 YP_004412847.1 COGs: COG0424 Nucleotide-binding protein implicated in inhibition of septum formation; InterPro IPR003697; KEGG: afn:Acfer_1830 maf protein; PFAM: Maf-like protein; SPTR: Maf-like protein SELSPUOL_02280; TIGRFAM: Maf-like protein; IMG reference gene:2504585874; PFAM: Maf-like protein; TIGRFAM: MAF protein YP_004412848.1 COGs: COG2003 DNA repair protein; InterPro IPR001405:IPR003583; KEGG: dae:Dtox_3340 DNA repair protein RadC; PFAM: Uncharacterised protein family UPF0758; SPTR: DNA repair protein RadC; TIGRFAM: Uncharacterised protein family UPF0758; IMG reference gene:2504585875; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc YP_004412849.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: toc:Toce_0740 rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Rod shape-determining protein MreB; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504585876; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004412850.1 COGs: COG1792 Cell shape-determining protein; InterPro IPR005223:IPR007221; KEGG: vpr:Vpar_1226 rod shape-determining protein MreC; PFAM: Rod shape-determining protein MreC; SPTR: Rod shape-determining protein MreC; TIGRFAM: Rod shape-determining protein MreC, subtype; IMG reference gene:2504585877; PFAM: rod shape-determining protein MreC; TIGRFAM: rod shape-determining protein MreC YP_004412851.1 InterPro IPR007227; KEGG: aoe:Clos_1763 hypothetical protein; PFAM: Cell shape-determining protein MreD; SPTR: Rod shape-determining protein MreD; TIGRFAM: Cell shape-determining protein MreD; IMG reference gene:2504585878; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD YP_004412852.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR017790:IPR005311:IPR001460; KEGG: afn:Acfer_1825 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 2; TIGRFAM: Penicillin-binding protein 2; IMG reference gene:2504585879; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2 YP_004412853.1 COGs: COG0850 Septum formation inhibitor; InterPro IPR013033:IPR005526; KEGG: dhd:Dhaf_4347 septum site-determining protein MinC; PFAM: Septum formation inhibitor MinC, C-terminal; SPTR: Probable septum site-determining protein minC; TIGRFAM: Septum formation inhibitor MinC; IMG reference gene:2504585880; PFAM: Septum formation inhibitor MinC, C-terminal domain; TIGRFAM: septum site-determining protein MinC YP_004412854.1 COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223:IPR002586; KEGG: ere:EUBREC_0094 septum site-determining protein MinD; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Septum site-determining protein MinD; TIGRFAM: Septum site-determining protein MinD; IMG reference gene:2504585881; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD YP_004412855.1 COGs: COG0851 Septum formation topological specificity factor; InterPro IPR005527; KEGG: drm:Dred_2542 cell division topological specificity factor MinE; PFAM: Septum formation topological specificity factor MinE; SPTR: Cell division topological specificity factor; TIGRFAM: Septum formation topological specificity factor MinE; IMG reference gene:2504585882; PFAM: Septum formation topological specificity factor MinE; TIGRFAM: cell division topological specificity factor MinE YP_004412856.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR011923:IPR001182; KEGG: afn:Acfer_1824 rod shape-determining protein RodA; PFAM: Cell cycle protein; SPTR: Rod shape-determining protein RodA; TIGRFAM: Rod shape-determining protein RodA; IMG reference gene:2504585883; PFAM: Cell cycle protein; TIGRFAM: rod shape-determining protein RodA YP_004412857.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: vpr:Vpar_1221 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504585884; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein YP_004412858.1 COGs: COG5011 conserved hypothetical protein; InterPro IPR018768; KEGG: afn:Acfer_1822 protein of unknown function DUF2344; PFAM: Protein of unknown function DUF2344; SPTR: Radical SAM domain protein; IMG reference gene:2504585885; PFAM: Uncharacterized protein conserved in bacteria (DUF2344); TIGRFAM: radical SAM-linked protein YP_004412859.1 COGs: COG1530 Ribonuclease G and E; InterPro IPR019307:IPR003029:IPR022967:IPR004659; KEGG: tjr:TherJR_2534 ribonuclease, Rne/Rng family; PFAM: RNA-binding protein AU-1/Ribonuclease E/G; Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: Cytoplasmic axial filament protein; TIGRFAM: Ribonuclease E/G; IMG reference gene:2504585886; PFAM: Ribonuclease E/G family; S1 RNA binding domain; TIGRFAM: ribonuclease, Rne/Rng family YP_004412860.1 COGs: COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3); InterPro IPR013027:IPR001327:IPR004099; KEGG: elm:ELI_3758 pyridine nucleotide-disulfide oxidoreductase family protein; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; PRIAM: Dihydrolipoyl dehydrogenase; SPTR: Pyridine nucleotide-disulfide oxidoreductase family protein; IMG reference gene:2504585887; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain YP_004412861.1 COGs: COG1344 Flagellin and related hook-associated protein; InterPro IPR001029; KEGG: dhd:Dhaf_4189 flagellin domain protein; PFAM: Flagellin, D0/D1 domain; SPTR: Flagellin; IMG reference gene:2504585888; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region YP_004412862.1 InterPro IPR011102:IPR008638; KEGG: mmw:Mmwyl1_0481 filamentous haemagglutinin outer membrane protein; PFAM: Filamentous haemagglutinin, N-terminal, bacterial; SMART: Signal transduction histidine kinase, HWE region; SPTR: Putative filamentous hemagglutinin family protein; TIGRFAM: Filamentous haemagglutinin, N-terminal, bacterial; IMG reference gene:2504585889; PFAM: haemagglutination activity domain; TIGRFAM: filamentous haemagglutinin family N-terminal domain YP_004412863.1 SPTR: Putative toxin-antitoxin system protein; IMG reference gene:2504585890 YP_004412864.1 InterPro IPR002716; KEGG: tde:TDE0236 PilT domain-containing protein; PFAM: PilT protein, N-terminal; SPTR: Toxin-antitoxin system, toxin component, PIN family; IMG reference gene:2504585891; PFAM: PIN domain YP_004412865.1 InterPro IPR001029; KEGG: rpt:Rpal_0707 flagellin domain protein; PFAM: Flagellin, D0/D1 domain; SPTR: Bacterial flagellin family protein; IMG reference gene:2504585892; PFAM: Bacterial flagellin N-terminal helical region; Bacterial flagellin C-terminal helical region YP_004412866.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585893 YP_004412867.1 COGs: COG3654 Prophage maintenance system killer protein; InterPro IPR003812:IPR006440; KEGG: ctc:CTC01933 death on curing protein; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Toxin-antitoxin system, toxin component, Fic family; TIGRFAM: Death-on-curing protein; IMG reference gene:2504585894; PFAM: Fic/DOC family; TIGRFAM: death-on-curing family protein YP_004412868.1 COGs: COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenase; InterPro IPR013149:IPR013154; KEGG: sea:SeAg_B4593 oxidoreductase, zinc-binding dehydrogenase family; PFAM: Alcohol dehydrogenase GroES-like; Alcohol dehydrogenase, C-terminal; PRIAM: L-iditol 2-dehydrogenase; SPTR: Putative L-iditol 2-dehydrogenase; IMG reference gene:2504585895; PFAM: Alcohol dehydrogenase GroES-like domain; Zinc-binding dehydrogenase YP_004412869.1 COGs: COG3914 O-linked N-acetylglucosamine transferase SPINDLY family; KEGG: gem:GM21_3825 tetratricopeptide TPR_2 repeat protein; SPTR: Putative TPR domain/SEC-C motif protein; IMG reference gene:2504585896 YP_004412870.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585897 YP_004412871.1 SPTR: 50S ribosomal protein L9; IMG reference gene:2504585898 YP_004412872.1 COGs: COG1897 Homoserine trans-succinylase; HAMAP: Homoserine O-succinyltransferase; InterPro IPR005697; KEGG: tjr:TherJR_2227 homoserine O-succinyltransferase; PFAM: Homoserine O-succinyltransferase; PRIAM: Homoserine O-succinyltransferase; SPTR: Homoserine O-succinyltransferase; TIGRFAM: Homoserine O-succinyltransferase; IMG reference gene:2504585899; PFAM: Homoserine O-succinyltransferase; TIGRFAM: homoserine O-succinyltransferase YP_004412873.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585900 YP_004412874.1 COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR010722:IPR006638; KEGG: thx:Thet_0618 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; Biotin/thiamin synthesis-associated protein; SPTR: Radical SAM domain protein; IMG reference gene:2504585901; PFAM: Radical SAM superfamily; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydE YP_004412875.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR012001:IPR012000:IPR011766; KEGG: dhd:Dhaf_3617 acetolactate synthase, large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504585902; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004412876.1 COGs: COG3119 Arylsulfatase A; InterPro IPR000917; KEGG: ppy:PPE_04397 hypothetical protein; PFAM: Sulfatase; SPTR: Putative sulfatase-domain-containing protein; IMG reference gene:2504585903; PFAM: Sulfatase YP_004412877.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR004789:IPR019455; KEGG: dhd:Dhaf_3616 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504585904; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004412878.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR001967; KEGG: pth:PTH_1876 D-alanyl-D-alanine carboxypeptidase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; IMG reference gene:2504585905; PFAM: D-alanyl-D-alanine carboxypeptidase YP_004412879.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR006638:IPR010722:IPR007197; KEGG: elm:ELI_3377 thiamine biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Biotin/thiamin synthesis-associated protein; Elongator protein 3/MiaB/NifB; SPTR: Putative thiazole biosynthesis protein ThiH; IMG reference gene:2504585906; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: iron-only hydrogenase maturation rSAM protein HydG; thiazole biosynthesis protein ThiH YP_004412880.1 COGs: COG3041 conserved hypothetical protein; InterPro IPR012753:IPR007712; KEGG: dae:Dtox_1713 addiction module toxin, RelE/StbE family; PFAM: Plasmid stabilisation system; SPTR: Toxin-antitoxin system, toxin component, RelE family; TIGRFAM: Addiction module toxin, RelE/StbE; IMG reference gene:2504585907; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin component, YafQ family; addiction module toxin, RelE/StbE family YP_004412881.1 InterPro IPR007337; KEGG: cdl:CDR20291_1760 addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504585908; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004412882.1 IMG reference gene:2504585909 YP_004412883.1 InterPro IPR001387; KEGG: ere:EUBREC_3010 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504585910; PFAM: Helix-turn-helix YP_004412884.1 InterPro IPR010035:IPR003749; KEGG: fsu:Fisuc_2908 thiamine biosynthesis protein ThiS; PFAM: ThiamineS; SPTR: Thiamine biosynthesis protein ThiS; TIGRFAM: ThiS, thiamine-biosynthesis; IMG reference gene:2504585911; PFAM: ThiS family; TIGRFAM: thiamine biosynthesis protein ThiS YP_004412885.1 COGs: COG2022 Uncharacterized protein of thiazole biosynthesis; InterPro IPR008867; KEGG: fsu:Fisuc_2910 thiazole synthase; PFAM: Thiazole biosynthesis; SPTR: Thiazole synthase; IMG reference gene:2504585912; PFAM: Thiazole biosynthesis protein ThiG YP_004412886.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR007197:IPR010722:IPR012726; KEGG: fsu:Fisuc_2911 thiamine biosynthesis protein ThiH; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; SMART: Biotin/thiamin synthesis-associated protein; SPTR: Thiazole biosynthesis protein ThiH; TIGRFAM: Thiazole biosynthesis ThiH; IMG reference gene:2504585913; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: thiazole biosynthesis protein ThiH YP_004412887.1 COGs: COG0352 Thiamine monophosphate synthase; InterPro IPR003733; KEGG: afn:Acfer_1200 thiamine monophosphate synthase; PFAM: Thiamine monophosphate synthase; SPTR: Thiamine-phosphate diphosphorylase; IMG reference gene:2504585914; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004412888.1 COGs: COG0114 Fumarase; HAMAP: Fumarate hydratase, class II; InterPro IPR005677:IPR022761:IPR018951; KEGG: afn:Acfer_2053 fumarate hydratase, class II; PFAM: Lyase 1, N-terminal; Fumarase C, C-terminal; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class II; TIGRFAM: Fumarate hydratase, class II; IMG reference gene:2504585915; PFAM: Fumarase C C-terminus; Lyase; TIGRFAM: fumarate hydratase, class II YP_004412889.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: apv:Apar_1269 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: SAM-dependent methyltransferase; IMG reference gene:2504585916; PFAM: Methyltransferase domain YP_004412890.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: bld:BLi02183 TlpB; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585917; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412891.1 InterPro IPR000086; KEGG: ere:EUBREC_0178 mutator MutT protein; PFAM: NUDIX hydrolase domain; SPTR: Mutator MutT protein; IMG reference gene:2504585918; PFAM: NUDIX domain YP_004412892.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: bao:BAMF_2923 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; Cache; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein signaling domain protein; IMG reference gene:2504585919; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412893.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004010:IPR004089; KEGG: bbe:BBR47_11740 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585920; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412894.1 SPTR: KH domain/HD domain protein; IMG reference gene:2504585921 YP_004412895.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585922 YP_004412896.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585923 YP_004412897.1 COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: elm:ELI_4527 hypothetical protein; PFAM: ROK; SPTR: ROK family protein; IMG reference gene:2504585924; PFAM: ROK family YP_004412898.1 COGs: COG1820 N-acetylglucosamine-6-phosphate deacetylase; InterPro IPR003764:IPR006680; KEGG: cbi:CLJ_B3061 N-acetylglucosamine-6-phosphate deacetylase; PFAM: Amidohydrolase 1; PRIAM: N-acetylglucosamine-6-phosphate deacetylase; SPTR: N-acetylglucosamine-6-phosphate deacetylase; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase; IMG reference gene:2504585925; PFAM: Amidohydrolase family; TIGRFAM: N-acetylglucosamine-6-phosphate deacetylase YP_004412899.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200:IPR000150; KEGG: afn:Acfer_0542 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD-superfamily hydrolase, family protein IIB; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504585926; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004412900.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200:IPR000150; KEGG: mta:Moth_0257 HAD family hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD hydrolase, IIB family; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504585927; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004412901.1 COGs: COG1660 P-loop-containing kinase; InterPro IPR005337; KEGG: vpr:Vpar_0559 hypothetical protein; SPTR: UPF0042 nucleotide-binding protein SELSPUOL_02221; IMG reference gene:2504585928; PFAM: P-loop ATPase protein family YP_004412902.1 COGs: COG0391 conserved hypothetical protein; InterPro IPR010119:IPR002882; KEGG: aar:Acear_0318 protein of unknown function UPF0052 and CofD; PFAM: LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052; SPTR: Putative structural protein; TIGRFAM: Uncharacterised protein family UPF0052; IMG reference gene:2504585929; PFAM: Uncharacterised protein family UPF0052; TIGRFAM: conserved hypothetical protein, cofD-related YP_004412903.1 COGs: COG1481 conserved hypothetical protein; InterPro IPR023054:IPR003802:IPR018478; KEGG: pth:PTH_2727 hypothetical protein; PFAM: Sporulation regulator WhiA, C-terminal; Sporulation regulator WhiA, N-terminal; SPTR: Putative sporulation transcription regulator whiA; TIGRFAM: Sporulation regulator WhiA; IMG reference gene:2504585930; PFAM: Sporulation Regulator WhiA N terminal; Sporulation Regulator WhiA C terminal domain; TIGRFAM: conserved hypothetical protein YP_004412904.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: ttr:Tter_2114 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase family protein; IMG reference gene:2504585931; PFAM: Polysaccharide deacetylase YP_004412905.1 KEGG: afn:Acfer_1539 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585932 YP_004412906.1 COGs: COG0517 FOG: CBS domain; InterPro IPR000644:IPR002912; KEGG: mta:Moth_1136 signal transduction protein; PFAM: Cystathionine beta-synthase, core; Amino acid-binding ACT; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain protein/ACT domain protein; IMG reference gene:2504585933; PFAM: CBS domain; ACT domain YP_004412907.1 COGs: COG0410 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: hmo:HM1_0494 branched-chain amino acid abc transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid ABC transporter, ATP-binding protein; IMG reference gene:2504585934; PFAM: ABC transporter YP_004412908.1 COGs: COG0411 ABC-type branched-chain amino acid transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: afn:Acfer_0018 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Amino acid ABC transporter, ATP-binding protein; IMG reference gene:2504585935; PFAM: ABC transporter; Branched-chain amino acid ATP-binding cassette transporter YP_004412909.1 COGs: COG4177 ABC-type branched-chain amino acid transport system permease component; InterPro IPR001851; KEGG: afn:Acfer_0017 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Amino acid ABC transporter, permease protein; IMG reference gene:2504585936; PFAM: Branched-chain amino acid transport system / permease component YP_004412910.1 COGs: COG0559 Branched-chain amino acid ABC-type transport system permease components; InterPro IPR001851; KEGG: afn:Acfer_0016 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: Amino acid ABC transporter, permease protein LivH; IMG reference gene:2504585937; PFAM: Branched-chain amino acid transport system / permease component YP_004412911.1 COGs: COG0683 ABC-type branched-chain amino acid transport systems periplasmic component; InterPro IPR001828; KEGG: gtn:GTNG_2930 branched chain amino acid ABC transporter amino acid-binding protein; PFAM: Extracellular ligand-binding receptor; SPTR: Branched-chain amino acid ABC transporter, amino acid-binding protein; IMG reference gene:2504585938; PFAM: Receptor family ligand binding region YP_004412912.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585939 YP_004412913.1 SPTR: H+ ATP synthase subunit C; IMG reference gene:2504585940 YP_004412914.1 InterPro IPR004316; KEGG: rdn:HMPREF0733_10506 integral membrane protein; PFAM: RAG1-activating protein-1-related; SPTR: Integral membrane protein; IMG reference gene:2504585941; PFAM: MtN3/saliva family YP_004412915.1 COGs: COG3585 Molybdopterin-binding protein; InterPro IPR004606:IPR005116; KEGG: pmu:PM0216 MopI; PFAM: Transport-associated OB, type 1; SPTR: Molybdenum transport regulatory protein ModE; TIGRFAM: Molybdenum-pterin binding; IMG reference gene:2504585942; PFAM: TOBE domain; TIGRFAM: molybdenum-pterin binding domain YP_004412916.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585943 YP_004412917.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cce:Ccel_0924 transcriptional regulator, BadM/Rrf2 family; PFAM: Transcription regulator Rrf2; SPTR: Rrf2 family protein; TIGRFAM: Transcription regulator Rrf2; IMG reference gene:2504585944; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004412918.1 COGs: COG0031 Cysteine synthase; InterPro IPR005856:IPR001926:IPR005859; KEGG: elm:ELI_3635 cysteine synthase A; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Cysteine synthase; SPTR: Cysteine synthase; TIGRFAM: Cysteine synthase K/M; Cysteine synthase A; IMG reference gene:2504585945; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: cysteine synthase A; cysteine synthases YP_004412919.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_0061 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB dependent siderophore receptor; IMG reference gene:2504585946; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004412920.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: vpr:Vpar_0062 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Putative iron compound ABC transporter, periplasmic iron compound-binding protein; IMG reference gene:2504585947; PFAM: Periplasmic binding protein YP_004412921.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: vpr:Vpar_0063 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: Hemin ABC transporter, permease protein; IMG reference gene:2504585948; PFAM: FecCD transport family YP_004412922.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: elm:ELI_3970 hypothetical protein; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Iron compound ABC transporter, ATP-binding protein; IMG reference gene:2504585949; PFAM: ABC transporter YP_004412923.1 COGs: COG0077 Prephenate dehydratase; InterPro IPR001086:IPR002912; KEGG: dau:Daud_1904 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Chorismate mutase/prephenate dehydratase; IMG reference gene:2504585950; PFAM: Prephenate dehydratase; ACT domain YP_004412924.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504585951; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004412925.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: tmt:Tmath_0501 methyl-accepting chemotaxis sensory transducer with cache sensor; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585952; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412926.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004010:IPR004089; KEGG: bpf:BpOF4_05865 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585953; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412927.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: bcy:Bcer98_1516 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein signaling domain protein; IMG reference gene:2504585954; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412928.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR004010; KEGG: bpf:BpOF4_19984 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585955; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412929.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004010:IPR004089; KEGG: btk:BT9727_0469 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504585956; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004412930.1 COGs: COG0525 Valyl-tRNA synthetase; HAMAP: Valyl-tRNA synthetase; InterPro IPR002303:IPR002300:IPR013155:IPR019499; KEGG: vpr:Vpar_1252 valyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; Valyl-tRNA synthetase, class Ia, tRNA-binding arm; PRIAM: Valine--tRNA ligase; SPTR: Valyl-tRNA synthetase; TIGRFAM: Valyl-tRNA synthetase; IMG reference gene:2504585957; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; Valyl tRNA synthetase tRNA binding arm; TIGRFAM: valyl-tRNA synthetase YP_004412931.1 COGs: COG0285 Folylpolyglutamate synthase; InterPro IPR013221:IPR001645:IPR004101; KEGG: afn:Acfer_0398 FolC bifunctional protein; PFAM: Mur ligase, central; Mur ligase, C-terminal; PRIAM: Tetrahydrofolate synthase; SPTR: Tetrahydrofolate synthase; TIGRFAM: Folylpolyglutamate synthetase; IMG reference gene:2504585958; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: folylpolyglutamate synthase/dihydrofolate synthase YP_004412932.1 COGs: COG3307 Lipid A core - O-antigen ligase; InterPro IPR007016; KEGG: vpr:Vpar_1250 O-antigen polymerase; PFAM: O-antigen ligase-related; SPTR: Putative O-antigen polymerase; IMG reference gene:2504585959; PFAM: O-Antigen ligase YP_004412933.1 COGs: COG0427 Acetyl-CoA hydrolase; InterPro IPR017821:IPR003702:IPR006472; KEGG: toc:Toce_1836 succinate CoA transferase; PFAM: Acetyl-CoA hydrolase/transferase; Citrate lyase, alpha subunit; PRIAM: Acetyl-CoA hydrolase; SPTR: Coenzyme A transferase PsecoA; TIGRFAM: Succinate CoA transferase; IMG reference gene:2504585960; PFAM: Acetyl-CoA hydrolase/transferase N-terminal domain; Citrate lyase, alpha subunit (CitF); TIGRFAM: succinate CoA transferases YP_004412934.1 COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR006098; KEGG: vpr:Vpar_1248 methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; IMG reference gene:2504585961; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain YP_004412935.1 COGs: COG2185 Methylmalonyl-CoA mutase C-terminal domain/subunit (cobalamin-binding); InterPro IPR006159:IPR006158; KEGG: vpr:Vpar_1247 cobalamin B12-binding domain protein; PFAM: Cobalamin (vitamin B12)-binding; SPTR: Methylmalonyl-CoA mutase; TIGRFAM: Methylmalonyl-CoA mutase, C-terminal; IMG reference gene:2504585962; PFAM: B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain YP_004412936.1 COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR003593:IPR005129; KEGG: vpr:Vpar_1246 LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: ATPase, AAA+ type, core; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein; IMG reference gene:2504585963; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase YP_004412937.1 InterPro IPR004360:IPR017515; KEGG: vpr:Vpar_1245 methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Methylmalonyl-CoA epimerase; TIGRFAM: Methylmalonyl-CoA epimerase; IMG reference gene:2504585964; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: methylmalonyl-CoA epimerase YP_004412938.1 COGs: COG4799 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta); InterPro IPR000022; KEGG: vpr:Vpar_1244 carboxyl transferase; PFAM: Carboxyl transferase; PRIAM: Propionyl-CoA carboxylase; SPTR: Propionyl-CoA carboxylase, beta subunit; IMG reference gene:2504585965; PFAM: Carboxyl transferase domain; TIGRFAM: methylmalonyl-CoA decarboxylase alpha subunit YP_004412939.1 SPTR: Methylmalonyl-CoA carboxytransferase; IMG reference gene:2504585966 YP_004412940.1 COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR000089; KEGG: aoe:Clos_0442 biotin/lipoyl attachment domain-containing protein; PFAM: Biotin/lipoyl attachment; SPTR: Methylmalonyl-CoA decarboxylase, gamma subunit; IMG reference gene:2504585967; PFAM: Biotin-requiring enzyme YP_004412941.1 InterPro IPR011528; KEGG: ccb:Clocel_2731 NERD domain-containing protein; PFAM: NERD; SPTR: Nuclease-related domain protein; IMG reference gene:2504585968; PFAM: Nuclease-related domain YP_004412942.1 SPTR: Putative flagella-related protein d; IMG reference gene:2504585969 YP_004412943.1 KEGG: afn:Acfer_1053 hypothetical protein; SPTR: Inner membrane protein YeeR; IMG reference gene:2504585970 YP_004412944.1 COGs: COG0790 FOG: TPR repeat SEL1 subfamily; InterPro IPR006597; KEGG: afn:Acfer_1052 Sel1 domain protein repeat-containing protein; SPTR: Putative tetratricopeptide repeat-containing domain protein; IMG reference gene:2504585971; PFAM: Sel1 repeat YP_004412945.1 KEGG: dba:Dbac_2567 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504585972 YP_004412946.1 InterPro IPR018841; KEGG: dba:Dbac_2568 hypothetical protein; PFAM: Protein of unknown function DUF2442; SPTR: Putative uncharacterized protein; IMG reference gene:2504585973; PFAM: Protein of unknown function (DUF2442) YP_004412947.1 COGs: COG0052 Ribosomal protein S2; InterPro IPR005706:IPR001865; KEGG: eat:EAT1b_2942 30S ribosomal protein S2; PFAM: Ribosomal protein S2; SPTR: 30S ribosomal protein S2; TIGRFAM: Ribosomal protein S2, bacteria/mitochondria/plastid; IMG reference gene:2504585974; PFAM: Ribosomal protein S2; TIGRFAM: ribosomal protein S2, bacterial type YP_004412948.1 COGs: COG0264 Translation elongation factor Ts; InterPro IPR001816:IPR000449:IPR014039; KEGG: afn:Acfer_1381 translation elongation factor Ts; PFAM: Translation elongation factor EFTs/EF1B, dimerisation; Ubiquitin-associated/translation elongation factor EF1B, N-terminal; SPTR: Translation elongation factor Ts; TIGRFAM: Translation elongation factor EFTs/EF1B; IMG reference gene:2504585975; PFAM: Elongation factor TS; UBA/TS-N domain; TIGRFAM: translation elongation factor Ts YP_004412949.1 COGs: COG0528 Uridylate kinase; InterPro IPR015963:IPR001048; KEGG: afn:Acfer_1380 uridylate kinase; PFAM: Aspartate/glutamate/uridylate kinase; SPTR: UMP kinase; TIGRFAM: Uridylate kinase, bacteria; IMG reference gene:2504585976; PFAM: Amino acid kinase family; TIGRFAM: uridylate kinase YP_004412950.1 COGs: COG0233 Ribosome recycling factor; InterPro IPR002661; KEGG: tjr:TherJR_1359 ribosome recycling factor; PFAM: Ribosome recycling factor; SPTR: Ribosome-recycling factor; TIGRFAM: Ribosome recycling factor; IMG reference gene:2504585977; PFAM: Ribosome recycling factor; TIGRFAM: ribosome recycling factor YP_004412951.1 SPTR: Putative aliphatic sulfonates transport permease protein; IMG reference gene:2504585978 YP_004412952.1 InterPro IPR001450; KEGG: clj:CLJU_c01440 ferredoxin; PFAM: 4Fe-4S binding domain; SPTR: Conserved domain protein; IMG reference gene:2504585979; PFAM: 4Fe-4S binding domain YP_004412953.1 COGs: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; InterPro IPR005854:IPR000836:IPR000583; KEGG: hfe:Hfelis_06440 amidophosphoribosyltransferase; PFAM: Glutamine amidotransferase, class-II; Phosphoribosyltransferase; PRIAM: Amidophosphoribosyltransferase; SPTR: Amidophosphoribosyltransferase; TIGRFAM: Amidophosphoribosyl transferase; IMG reference gene:2504585980; PFAM: Phosphoribosyl transferase domain; Glutamine amidotransferases class-II; TIGRFAM: amidophosphoribosyltransferase YP_004412954.1 COGs: COG2831 Hemolysin activation/secretion protein; InterPro IPR000184:IPR013686; KEGG: pna:Pnap_3704 polypeptide-transport-associated domain-containing protein; PFAM: Polypeptide-transport-associated, ShlB-type; Bacterial surface antigen (D15); SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504585981; PFAM: POTRA domain, ShlB-type; Surface antigen YP_004412955.1 InterPro IPR007159:IPR006339; KEGG: tjr:TherJR_0092 transcriptional regulator, AbrB family; PFAM: Transcription regulator AbrB/SpoV, predicted; SMART: Transcription regulator AbrB/SpoV, predicted; SPTR: Transition state transcriptional regulatory protein AbrB; TIGRFAM: Transcription regulator AbrB; IMG reference gene:2504585982; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family YP_004412956.1 COGs: COG0143 Methionyl-tRNA synthetase; HAMAP: Methionyl-tRNA synthetase, class Ia; InterPro IPR014758:IPR004495:IPR015413:IPR002547; KEGG: afn:Acfer_1438 methionyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class I (M); tRNA-binding domain; PRIAM: Methionine--tRNA ligase; SPTR: Methionine--tRNA ligase; TIGRFAM: Methionyl-tRNA synthetase, class Ia; Methionyl-tRNA synthetase, class Ia, beta subunit, C-terminal; IMG reference gene:2504585983; PFAM: Anticodon-binding domain; tRNA synthetases class I (M); Putative tRNA binding domain; TIGRFAM: methionyl-tRNA synthetase C-terminal region/beta chain; methionyl-tRNA synthetase YP_004412957.1 COGs: COG0084 Mg-dependent DNase; InterPro IPR015991:IPR001130; KEGG: hmo:HM1_0751 hydrolase, TatD family; PFAM: Deoxyribonuclease, TatD-related; SPTR: Hydrolase, TatD family; TIGRFAM: Deoxyribonuclease, TatD Mg-dependent, prokaryote; IMG reference gene:2504585984; PFAM: TatD related DNase; TIGRFAM: hydrolase, TatD family YP_004412958.1 COGs: COG3584 conserved hypothetical protein; InterPro IPR010611; KEGG: vpr:Vpar_0621 3D domain protein; PFAM: 3D; SPTR: Hypothetical membrane associated protein; IMG reference gene:2504585985; PFAM: 3D domain YP_004412959.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504585986 YP_004412960.1 COGs: COG1113 Gamma-aminobutyrate permease and related permease; InterPro IPR004841; KEGG: dhd:Dhaf_1325 amino acid permease-associated region; PFAM: Amino acid permease domain; SPTR: Aromatic amino acid transporter; IMG reference gene:2504585987; PFAM: Amino acid permease YP_004412961.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001173; KEGG: pjd:Pjdr2_5756 transferase hexapeptide repeat containing protein; PFAM: Glycosyl transferase, family 2; SPTR: Chloramphenicol O-acetyltransferase; IMG reference gene:2504585988; PFAM: Glycosyl transferase family 2 YP_004412962.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: eel:EUBELI_00266 hypothetical protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504585989; PFAM: Glycosyl transferase family 2 YP_004412963.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: cbb:CLD_1847 glycosyltransferase; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyltransferase; IMG reference gene:2504585990; PFAM: Glycosyl transferase family 2 YP_004412964.1 COGs: COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon); InterPro IPR013446:IPR005835; KEGG: pru:PRU_0434 glucose-1-phosphate cytidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate cytidylyltransferase; SPTR: Glucose-1-phosphate cytidylyltransferase; TIGRFAM: Glucose-1-phosphate cytidylyltransferase; IMG reference gene:2504585991; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate cytidylyltransferase YP_004412965.1 COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR001173; KEGG: chy:CHY_0980 glycosyl transferase family protein; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504585992; PFAM: Glycosyl transferase family 2 YP_004412966.1 InterPro IPR006342; KEGG: tmz:Tmz1t_2883 methyltransferase FkbM family; SPTR: Methyltransferase, FkbM family; TIGRFAM: Methyltransferase FkbM; IMG reference gene:2504585993; PFAM: Met-10+ like-protein; TIGRFAM: methyltransferase, FkbM family YP_004412967.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: glo:Glov_0787 pyruvate carboxyltransferase; PFAM: Pyruvate carboxyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504585994; PFAM: HMGL-like YP_004412968.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: nmr:Nmar_0026 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase LinC; IMG reference gene:2504585995; PFAM: short chain dehydrogenase YP_004412969.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR011766:IPR012001:IPR012000; KEGG: csh:Closa_0571 thiamine pyrophosphate protein domain protein TPP-binding protein; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central domain; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase; IMG reference gene:2504585996; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain YP_004412970.1 InterPro IPR004360; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase; IMG reference gene:2504585997; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004412971.1 COGs: COG0337 3-dehydroquinate synthetase; InterPro IPR002658; KEGG: glo:Glov_0789 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; IMG reference gene:2504585998; PFAM: 3-dehydroquinate synthase YP_004412972.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197; KEGG: azl:AZL_f00370 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Putative radical SAM domain protein; IMG reference gene:2504585999; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004412973.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509; KEGG: vpa:VP1321 putative dTDP-glucose 4-6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; SPTR: Putative nucleotide sugar dehydratase; IMG reference gene:2504586000; PFAM: NAD dependent epimerase/dehydratase family YP_004412974.1 KEGG: tjr:TherJR_2954 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586001; TIGRFAM: rSAM-modified six-cysteine peptide SCIFF YP_004412975.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197:IPR006638; KEGG: afn:Acfer_0548 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504586002; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain; six-Cys-in-45 modification radical SAM protein YP_004412976.1 COGs: COG1349 Transcriptional regulators of sugar metabolism; InterPro IPR001034:IPR014036; KEGG: fnu:FN0228 DeoR family transcriptional regulator; PFAM: HTH transcriptional regulator, DeoR; HTH transcriptional regulator, DeoR N-terminal; SMART: HTH transcriptional regulator, DeoR N-terminal; SPTR: Transcriptional regulator, DeoR family; IMG reference gene:2504586003; PFAM: Bacterial regulatory proteins, deoR family; DeoR-like helix-turn-helix domain YP_004412977.1 COGs: COG3395 conserved hypothetical protein; InterPro IPR010737; KEGG: fnu:FN0227 hypothetical protein; PFAM: Protein of unknown function, DUF1537; SPTR: Putative uncharacterized protein; IMG reference gene:2504586004; PFAM: Protein of unknown function, DUF1537 YP_004412978.1 COGs: COG1995 Pyridoxal phosphate biosynthesis protein; InterPro IPR005255; KEGG: fnu:FN0226 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; PRIAM: 4-hydroxythreonine-4-phosphate dehydrogenase; SPTR: 4-hydroxythreonine-4-phosphate dehydrogenase; TIGRFAM: Pyridoxal phosphate (active vitamin B6) biosynthesis PdxA; IMG reference gene:2504586005; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase YP_004412979.1 COGs: COG2610 H+/gluconate symporter and related permease; InterPro IPR003474; KEGG: fnu:FN0225 gluconate permease; PFAM: Gluconate transporter; SPTR: Transporter, gluconate:H+ symporter family; TIGRFAM: Gluconate transporter; IMG reference gene:2504586006; PFAM: GntP family permease; TIGRFAM: gluconate transporter YP_004412980.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: cpf:CPF_0681 rubredoxin/rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubredoxin/rubrerythrin; IMG reference gene:2504586007; PFAM: Rubrerythrin YP_004412981.1 COGs: COG0802 ATPase or kinase; InterPro IPR003442; KEGG: cce:Ccel_0799 protein of unknown function UPF0079; PFAM: Uncharacterised protein family UPF0079, ATPase bacteria; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0079, ATPase bacteria; IMG reference gene:2504586008; PFAM: Uncharacterised P-loop hydrolase UPF0079; TIGRFAM: ATPase, YjeE family YP_004412982.1 COGs: COG1214 Inactive homolog of metal-dependent protease putative molecular chaperone; InterPro IPR022496:IPR000905; KEGG: afn:Acfer_1580 peptidase M22 glycoprotease; PFAM: Peptidase M22, glycoprotease; SPTR: Universal bacterial protein YeaZ; TIGRFAM: Conserved hypothetical protein CHP03725, YeaZ; IMG reference gene:2504586009; PFAM: Glycoprotease family; TIGRFAM: universal bacterial protein YeaZ YP_004412983.1 COGs: COG0456 Acetyltransferase; InterPro IPR006464:IPR000182; KEGG: eat:EAT1b_2086 ribosomal-protein-alanine acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Ribosomal-protein-alanine acetyltransferase; TIGRFAM: Ribosomal-protein-alanine acetyltransferase; IMG reference gene:2504586010; PFAM: Acetyltransferase (GNAT) family; TIGRFAM: ribosomal-protein-alanine acetyltransferase YP_004412984.1 COGs: COG0533 Metal-dependent protease with possible chaperone activity; InterPro IPR017861:IPR000905:IPR022450; KEGG: vpr:Vpar_1038 metalloendopeptidase, glycoprotease family; PFAM: Peptidase M22, glycoprotease; PRIAM: O-sialoglycoprotein endopeptidase; SPTR: Probable O-sialoglycoprotein endopeptidase; TIGRFAM: Peptidase M22, glycoprotease, subgroup; Peptidase M22, O-sialoglycoprotein peptidase; IMG reference gene:2504586011; PFAM: Glycoprotease family; TIGRFAM: putative glycoprotease GCP; metallohydrolase, glycoprotease/Kae1 family YP_004412985.1 KEGG: swo:Swol_0236 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586012 YP_004412986.1 InterPro IPR008254; KEGG: dds:Ddes_0527 flavodoxin family protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin family protein; IMG reference gene:2504586013 YP_004412987.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504586014 YP_004412988.1 COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR017688:IPR000192; KEGG: bfs:BF1899 putative LPS biosynthesis related 2-aminoethylphosphonate pyruvate aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: 2-aminoethylphosphonate--pyruvate transaminase; SPTR: Nucleotidyl transferase/aminotransferase, class V; TIGRFAM: 2-aminoethylphosphonate aminotransferase; IMG reference gene:2504586015; PFAM: Aminotransferase class-V; TIGRFAM: 2-aminoethylphosphonate aminotransferase YP_004412989.1 InterPro IPR013216; KEGG: cyj:Cyan7822_6770 methyltransferase type 12; PFAM: Methyltransferase type 11; SPTR: Methyltransferase; IMG reference gene:2504586016; PFAM: Methyltransferase domain YP_004412990.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR017684:IPR011766; KEGG: ols:Olsu_0592 phosphonopyruvate decarboxylase; PFAM: Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Phosphonopyruvate decarboxylase; SPTR: Phosphonopyruvate decarboxylase; TIGRFAM: Phosphonopyruvate decarboxylase; IMG reference gene:2504586017; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: phosphonopyruvate decarboxylase YP_004412991.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586018 YP_004412992.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586019 YP_004412993.1 KEGG: vcn:VOLCADRAFT_91593 hypothetical protein; SPTR: Keratin, type II cytoskeletal I; IMG reference gene:2504586020 YP_004412994.1 COGs: COG2217 Cation transport ATPase; InterPro IPR006416:IPR001757:IPR008250:IPR005834; KEGG: ccb:Clocel_3930 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Heavy metal translocating P-type ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504586021; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004412995.1 KEGG: ccb:Clocel_2128 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586022; PFAM: Uncharacterized protein conserved in bacteria (DUF2325) YP_004412996.1 COGs: COG1918 Fe2+ transport system protein A; InterPro IPR007167; KEGG: bpb:bpr_I2290 ferrous iron transport protein FeoA/B; PFAM: Ferrous iron transporter, FeoA subunit; SMART: Ferrous iron transporter, FeoA subunit; SPTR: Ferrous iron transport protein B; IMG reference gene:2504586023; PFAM: FeoA domain YP_004412997.1 COGs: COG0370 Fe2+ transport system protein B; InterProIPR003373:IPR011642:IPR011640:IPR011619:IPR 005225; KEGG: drm:Dred_2723 ferrous iron transport protein B; PFAM: Ferrous iron transport protein B, N-terminal; Ferrous iron transport protein B, C-terminal; Nucleoside recognition; SPTR: Ferrous iron transport protein B; TIGRFAM: Ferrous iron transport protein B; Small GTP-binding protein; IMG reference gene:2504586024; PFAM: Ferrous iron transport protein B; Ferrous iron transport protein B C terminus; Nucleoside recognition; TIGRFAM: ferrous iron transporter FeoB YP_004412998.1 SPTR: Putative membrane protein; IMG reference gene:2504586025 YP_004412999.1 COGs: COG3315 O-Methyltransferase involved in polyketide biosynthesis; KEGG: mac:MA3472 hypothetical protein; SPTR: Putative tetracenomycin polyketide synthesis O-methyltransferase TcmP; IMG reference gene:2504586026; PFAM: Leucine carboxyl methyltransferase YP_004413000.1 COGs: COG0464 ATPase of the AAA+ class; InterPro IPR003593:IPR003959; KEGG: cbo:CBO2323 ATPase; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: ATPase, AAA-superfamily; IMG reference gene:2504586027; PFAM: ATPase family associated with various cellular activities (AAA) YP_004413001.1 InterPro IPR000209; KEGG: cno:NT01CX_2155 hypothetical protein; PFAM: Peptidase S8/S53, subtilisin/kexin/sedolisin; SPTR: Putative uncharacterized protein; IMG reference gene:2504586028; PFAM: Subtilase family YP_004413002.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586029 YP_004413003.1 COGs: COG0849 Actin-like ATPase involved in cell division; InterPro IPR003494; KEGG: bbe:BBR47_41670 hypothetical protein; PFAM: Cell division protein FtsA domain; SMART: Cell division protein FtsA domain; SPTR: Putative cell division protein FtsA; IMG reference gene:2504586031; PFAM: Cell division protein FtsA; TIGRFAM: cell division protein FtsA YP_004413004.1 COGs: COG1461 kinase related to dihydroxyacetone kinase; InterPro IPR004007; KEGG: chy:CHY_1528 DAK2 domain-containing protein; PFAM: Dak phosphatase; SPTR: Putative DAK2 domain protein; IMG reference gene:2504586032; PFAM: DAK2 domain YP_004413005.1 COGs: COG2707 membrane protein; InterPro IPR007382; KEGG: afn:Acfer_0268 protein of unknown function DUF441; PFAM: Uncharacterised protein family UPF0756, transmembrame; SPTR: UPF0756 membrane protein SELSPUOL_02096; IMG reference gene:2504586033; PFAM: Protein of unknown function (DUF441) YP_004413006.1 KEGG: vpr:Vpar_1746 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586034 YP_004413007.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001320:IPR001638; KEGG: afn:Acfer_0649 extracellular solute-binding protein family 3; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; Ionotropic glutamate receptor; SPTR: Putative cysteine ABC transporter, periplasmic cysteine-binding protein; IMG reference gene:2504586035; PFAM: Bacterial extracellular solute-binding proteins, family 3; TIGRFAM: lysine-arginine-ornithine-binding periplasmic protein YP_004413008.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: vpr:Vpar_0796 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Glutamine ABC transporter, permease protein; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; IMG reference gene:2504586036; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family; ectoine/hydroxyectoine ABC transporter, permease protein EhuC YP_004413009.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: afn:Acfer_0651 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Glutamine ABC transporter, ATP-binding protein; IMG reference gene:2504586037; PFAM: ABC transporter YP_004413010.1 COGs: COG0335 Ribosomal protein L19; InterPro IPR001857; KEGG: vpr:Vpar_0974 ribosomal protein L19; PFAM: Ribosomal protein L19; SPTR: 50S ribosomal protein L19; TIGRFAM: Ribosomal protein L19; IMG reference gene:2504586038; PFAM: Ribosomal protein L19; TIGRFAM: ribosomal protein L19, bacterial type YP_004413011.1 COGs: COG0681 Signal peptidase I; InterPro IPR000223:IPR019759; KEGG: afn:Acfer_0473 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; PRIAM: Signal peptidase I; SPTR: Signal peptidase I; TIGRFAM: Peptidase S26A, signal peptidase I; IMG reference gene:2504586039; PFAM: Peptidase S24-like; TIGRFAM: signal peptidase I, bacterial type YP_004413012.1 KEGG: ols:Olsu_0417 acetyltransferase; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504586040 YP_004413013.1 InterPro IPR002921; KEGG: afn:Acfer_0382 lipase class 3; PFAM: Lipase, class 3; SPTR: Lipase; IMG reference gene:2504586041; PFAM: Lipase (class 3) YP_004413014.1 COGs: COG2264 Ribosomal protein L11 methylase; HAMAP: Ribosomal protein L11 methyltransferase; InterPro IPR004498:IPR010456; KEGG: afn:Acfer_0709 ribosomal protein L11 methyltransferase; PFAM: Ribosomal L11 methyltransferase, PrmA; SPTR: Ribosomal protein L11 methyltransferase; TIGRFAM: Ribosomal protein L11 methyltransferase; IMG reference gene:2504586042; PFAM: Ribosomal protein L11 methyltransferase (PrmA); TIGRFAM: ribosomal protein L11 methyltransferase YP_004413015.1 COGs: COG1385 conserved hypothetical protein; InterPro IPR006700; KEGG: adg:Adeg_0610 protein of unknown function DUF558; PFAM: Ribosomal RNA small subunit methyltransferase E; SPTR: RNA methyltransferase, RsmE family; TIGRFAM: Ribosomal RNA small subunit methyltransferase E; IMG reference gene:2504586043; PFAM: RNA methyltransferase; TIGRFAM: RNA methyltransferase, RsmE family YP_004413016.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR006638:IPR005839:IPR006467:IPR013848:IPR 007197; KEGG: afn:Acfer_0711 RNA modification enzyme, MiaB family; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: tRNA-I(6)A37 thiotransferase enzyme MiaB; TIGRFAM: Methylthiotransferase; MiaB-like tRNA modifying enzyme; IMG reference gene:2504586044; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: MiaB-like tRNA modifying enzyme; radical SAM methylthiotransferase, MiaB/RimO family YP_004413017.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586045 YP_004413018.1 KEGG: bde:BDP_0479 putative histidine kinase; SPTR: Putative uncharacterized protein; IMG reference gene:2504586046 YP_004413019.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: elm:ELI_2014 hypothetical protein; PFAM: LytTr, DNA-binding domain; Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; LytTr, DNA-binding domain; SPTR: LytTr DNA-binding domain protein; IMG reference gene:2504586047; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004413020.1 InterPro IPR005821; KEGG: mgm:Mmc1_0798 ion transport protein; PFAM: Ion transport; SPTR: Voltage-gated sodium channel; IMG reference gene:2504586048; PFAM: Ion transport protein YP_004413021.1 InterPro IPR008638:IPR011102; KEGG: met:M446_5785 filamentous haemagglutinin outer membrane protein; PFAM: Filamentous haemagglutinin, N-terminal, bacterial; SMART: Signal transduction histidine kinase, HWE region; SPTR: Putative filamentous hemagglutinin family protein; TIGRFAM: Filamentous haemagglutinin, N-terminal, bacterial; IMG reference gene:2504586049; PFAM: haemagglutination activity domain; TIGRFAM: filamentous haemagglutinin family N-terminal domain YP_004413022.1 COGs: COG2831 Hemolysin activation/secretion protein; InterPro IPR013686:IPR000184; KEGG: pfl:PFL_1466 HlyB family hemolysin activator protein; PFAM: Polypeptide-transport-associated, ShlB-type; Bacterial surface antigen (D15); SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504586050; PFAM: POTRA domain, ShlB-type YP_004413023.1 COGs: COG3041 conserved hypothetical protein; InterPro IPR012753:IPR007712; KEGG: clo:HMPREF0868_1611 RelE family toxin-antitoxin system toxin protein; PFAM: Plasmid stabilisation system; SPTR: Addiction module toxin component YafQ; TIGRFAM: Addiction module toxin, RelE/StbE; IMG reference gene:2504586051; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin component, YafQ family; addiction module toxin, RelE/StbE family YP_004413024.1 COGs: COG3077 DNA-damage-inducible protein J; InterPro IPR007337; KEGG: clo:HMPREF0868_1610 putative toxin-antitoxin system antitoxin component ribbon-helix-helix domain-containing protein; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504586052; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004413025.1 COGs: COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolase; InterPro IPR001310; KEGG: ckr:CKR_0820 hypothetical protein; PFAM: Histidine triad (HIT) protein; SPTR: Purine nucleoside phosphoramidase; IMG reference gene:2504586053; PFAM: HIT domain YP_004413026.1 InterPro IPR001911; KEGG: vpr:Vpar_0888 ribosomal protein S21; PFAM: Ribosomal protein S21; SPTR: 30S ribosomal protein S21; TIGRFAM: Ribosomal protein S21; IMG reference gene:2504586054; PFAM: Ribosomal protein S21; TIGRFAM: ribosomal protein S21 YP_004413027.1 COGs: COG0595 hydrolase of the metallo-beta-lactamase superfamily; InterPro IPR001279:IPR004613:IPR011108; KEGG: afn:Acfer_1020 RNA-metabolising metallo-beta-lactamase; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase family protein; TIGRFAM: Ribonuclease J; IMG reference gene:2504586055; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; TIGRFAM: conserved hypothetical protein YP_004413028.1 InterPro IPR001387; KEGG: afn:Acfer_1162 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586056; PFAM: Helix-turn-helix YP_004413029.1 COGs: COG0243 Anaerobic dehydrogenase typically selenocysteine-containing; InterPro IPR006963:IPR006657:IPR006656; KEGG: gsu:GSU0880 molybdopterin oxidoreductase family protein; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding domain; Molybdopterin oxidoreductase, Fe4S4 domain; PRIAM: Nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; SPTR: Molybdopterin oxidoreductase family protein; IMG reference gene:2504586058; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; Molybdopterin oxidoreductase Fe4S4 domain YP_004413030.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterPro IPR000432; KEGG: cdl:CDR20291_3230 putative DNA mismatch repair protein; PFAM: DNA mismatch repair protein MutS, C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; SPTR: Putative MutS domain protein; IMG reference gene:2504586059; PFAM: MutS domain V YP_004413031.1 InterPro IPR007337; KEGG: dhd:Dhaf_2606 addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504586060; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004413032.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: ahe:Arch_0467 addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB; SPTR: Addiction module toxin, Txe/YoeB family; TIGRFAM: Addiction module toxin, Txe/YoeB; IMG reference gene:2504586061; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_004413033.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR005895:IPR003439; KEGG: rmr:Rmar_1411 heme exporter protein CcmA; PFAM: ABC transporter-like; PRIAM: Heme-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Heme ABC exporter, ATP-binding protein CcmA; TIGRFAM: ABC transporter, haem export, CcmA; IMG reference gene:2504586062; PFAM: ABC transporter; TIGRFAM: heme ABC exporter, ATP-binding protein CcmA YP_004413034.1 InterPro IPR003544; KEGG: srm:SRM_02413 heme exporter protein B; PFAM: Cytochrome c-type biogenesis protein CcmB; SPTR: Putative cytochrome c-type biogenesis protein CcmB; IMG reference gene:2504586063; PFAM: CcmB protein YP_004413035.1 InterPro IPR002541; KEGG: cag:Cagg_1852 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Heme exporter protein C; IMG reference gene:2504586064; PFAM: Cytochrome C assembly protein YP_004413036.1 InterPro IPR004329; KEGG: hau:Haur_2721 hypothetical protein; PFAM: CcmE/CycJ protein; SPTR: Putative cytochrome c-type biogenesis protein CcmE; IMG reference gene:2504586065; PFAM: CcmE YP_004413037.1 COGs: COG1138 Cytochrome c biogenesis factor; InterPro IPR002541; KEGG: cts:Ctha_0617 cytochrome c assembly protein; PFAM: Cytochrome c assembly protein; SPTR: Cytochrome c assembly protein; IMG reference gene:2504586066; PFAM: Cytochrome C assembly protein; TIGRFAM: c-type cytochrome biogenesis protein CcmF YP_004413038.1 COGs: COG3005 Nitrate/TMAO reductase membrane-bound tetraheme cytochrome c subunit; InterPro IPR005126; KEGG: sat:SYN_02615 cytochrome c-type protein; PFAM: NapC/NirT cytochrome c, N-terminal; SPTR: Putative cytochrome c nitrite reductase, small subunit NrfH; IMG reference gene:2504586067; PFAM: NapC/NirT cytochrome c family, N-terminal region; TIGRFAM: cytochrome c nitrate reductase, small subunit YP_004413039.1 COGs: COG3303 Formate-dependent nitrite reductase periplasmic cytochrome c552 subunit; InterPro IPR003321; KEGG: sat:SYN_02616 cytochrome c552; PFAM: Cytochrome c552; PRIAM: Nitrite reductase (cytochrome; ammonia-forming); SPTR: Nitrite reductase; IMG reference gene:2504586068; PFAM: Cytochrome c552 YP_004413040.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089:IPR013163; KEGG: bpb:bpr_I1155 methyl-accepting chemotaxis protein McpK; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache, type 2; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504586069; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413041.1 COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235:IPR000277; KEGG: afn:Acfer_0064 O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine sulfhydrylase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; IMG reference gene:2504586070; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase YP_004413042.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586071 YP_004413043.1 COGs: COG1893 Ketopantoate reductase; InterPro IPR003710:IPR013332:IPR013752; KEGG: swo:Swol_1181 putative oxidoreductase; PFAM: Ketopantoate reductase ApbA/PanE, N-terminal; Ketopantoate reductase ApbA/PanE, C-terminal; SPTR: 2-dehydropantoate 2-reductase; TIGRFAM: Ketopantoate reductase ApbA/PanE; IMG reference gene:2504586072; PFAM: Ketopantoate reductase PanE/ApbA; Ketopantoate reductase PanE/ApbA C terminal; TIGRFAM: 2-dehydropantoate 2-reductase YP_004413044.1 COGs: COG1929 Glycerate kinase; InterPro IPR004381; KEGG: cdl:CDR20291_2923 glycerate kinase; PFAM: Glycerate kinase; PRIAM: Glycerate kinase; SPTR: Glycerate kinase; TIGRFAM: Glycerate kinase; IMG reference gene:2504586073; PFAM: Glycerate kinase family; TIGRFAM: glycerate kinase YP_004413045.1 COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: cce:Ccel_2696 filamentation induced by cAMP protein Fic; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Cell filamentation protein; IMG reference gene:2504586075; PFAM: Fic/DOC family YP_004413046.1 COGs: COG0328 Ribonuclease HI; HAMAP: Ribonuclease H; InterPro IPR002156:IPR022892; KEGG: dak:DaAHT2_2667 ribonuclease H; PFAM: Ribonuclease H domain; SPTR: Ribonuclease H; IMG reference gene:2504586076; PFAM: RNase H; Caulimovirus viroplasmin YP_004413047.1 InterPro IPR008523; PFAM: Protein of unknown function DUF805; SPTR: Putative uncharacterized protein; IMG reference gene:2504586077; PFAM: Protein of unknown function (DUF805) YP_004413048.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695; KEGG: mla:Mlab_0394 hypothetical protein; PFAM: Ppx/GppA phosphatase; SPTR: Putative exopolyphosphatase; IMG reference gene:2504586078; PFAM: Ppx/GppA phosphatase family YP_004413049.1 COGs: COG0730 permease; InterPro IPR002781; KEGG: bca:BCE_0337 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative membrane protein; IMG reference gene:2504586079; PFAM: Sulfite exporter TauE/SafE YP_004413050.1 COGs: COG0322 Nuclease subunit of the excinuclease complex; HAMAP: Excinuclease ABC, C subunit; InterPro IPR000305:IPR001943:IPR001162:IPR004791; KEGG: dae:Dtox_3952 excinuclease ABC subunit C; PFAM: Excinuclease ABC, C subunit, C-terminal; Excinuclease ABC, C subunit, N-terminal; UvrB/UvrC protein; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: UvrABC system protein C; TIGRFAM: Excinuclease ABC, C subunit; IMG reference gene:2504586080; PFAM: UvrB/uvrC motif; UvrC Helix-hairpin-helix N-terminal; GIY-YIG catalytic domain; TIGRFAM: excinuclease ABC, C subunit YP_004413051.1 COGs: COG1598 conserved hypothetical protein; InterPro IPR005357; KEGG: dsy:DSY3841 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; SPTR: Toxin-antitoxin system, antitoxin component, HicB family; IMG reference gene:2504586081; PFAM: Uncharacterised protein family (UPF0150) YP_004413052.1 COGs: COG0468 RecA/RadA recombinase; InterPro IPR003593:IPR013765; KEGG: dhd:Dhaf_3106 RecA protein; PFAM: DNA recombination and repair protein RecA; SMART: ATPase, AAA+ type, core; SPTR: Protein recA; TIGRFAM: DNA recombination and repair protein RecA; IMG reference gene:2504586083; PFAM: recA bacterial DNA recombination protein; TIGRFAM: protein RecA YP_004413053.1 COGs: COG2137 conserved hypothetical protein; InterPro IPR003783; KEGG: aac:Aaci_1474 regulatory protein RecX; PFAM: Regulatory protein RecX; SPTR: Regulatory protein RecX; IMG reference gene:2504586084; PFAM: RecX family YP_004413054.1 COGs: COG0519 GMP synthase PP-ATPase domain/subunit; HAMAP: GMP synthase; InterProIPR000991:IPR004506:IPR001674:IPR004739:IPR 022955; KEGG: csh:Closa_2953 GMP synthase, large subunit; PFAM: GMP synthase, C-terminal; Glutamine amidotransferase class-I, C-terminal; tRNA-specific 2-thiouridylase; PRIAM: GMP synthase (glutamine-hydrolyzing); SPTR: GMP synthase [glutamine-hydrolyzing]; TIGRFAM: GMP synthase, C-terminal; GMP synthase, N-terminal; IMG reference gene:2504586085; PFAM: GMP synthase C terminal domain; Glutamine amidotransferase class-I; tRNA methyl transferase; TIGRFAM: GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit; GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit YP_004413055.1 COGs: COG0338 Site-specific DNA methylase; InterPro IPR012327; KEGG: mpe:MYPE1230 adenine-specific DNA methyltransferase; PFAM: D12 class N6 adenine-specific DNA methyltransferase; SPTR: DNA adenine methylase; TIGRFAM: D12 class N6 adenine-specific DNA methyltransferase; IMG reference gene:2504586086; PFAM: D12 class N6 adenine-specific DNA methyltransferase; TIGRFAM: DNA adenine methylase (dam) YP_004413056.1 InterPro IPR007637; KEGG: eel:EUBELI_01767 type II restriction enzyme; PFAM: Restriction endonuclease, type II, DpmII-like; PRIAM: Type II site-specific deoxyribonuclease; SPTR: Type II restriction enzyme DpnII; IMG reference gene:2504586087; PFAM: DpnII restriction endonuclease YP_004413057.1 SPTR: Putative aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; IMG reference gene:2504586088 YP_004413058.1 COGs: COG1041 DNA modification methylase; InterPro IPR000241; KEGG: smf:Smon_1038 putative RNA methylase; PFAM: Putative RNA methylase; SPTR: Putative DNA methylase; IMG reference gene:2504586089; PFAM: Putative RNA methylase family UPF0020 YP_004413059.1 KEGG: nmi:NMO_0325 putative ATP/GTP-binding protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586090 YP_004413060.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; InterPro IPR001584; KEGG: apa:APP7_A0002 transposase; PFAM: Integrase, catalytic core; SPTR: Transposase InsI for insertion sequence element IS30B/C/D; IMG reference gene:2504586091; PFAM: Integrase core domain YP_004413061.1 InterPro IPR020941; KEGG: ccv:CCV52592_1800 riboflavin biosynthesis protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586092; PFAM: Suppressor of fused protein (SUFU) YP_004413062.1 COGs: COG3328 Transposase and inactivated derivatives; InterPro IPR001207; KEGG: efa:EF1855 IS256 family transposase; PFAM: Transposase, mutator type; SPTR: Transposase, Mutator family; IMG reference gene:2504586093; PFAM: Transposase, Mutator family YP_004413063.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504586094 YP_004413064.1 InterPro IPR001584; KEGG: bbe:BBR47_48770 transposase orfB for insertion sequence element IS3 family; PFAM: Integrase, catalytic core; SPTR: Putative transposase InsK; IMG reference gene:2504586095; PFAM: Integrase core domain YP_004413065.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586096 YP_004413066.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586097 YP_004413067.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586098 YP_004413068.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586099 YP_004413069.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: elm:ELI_2110 methylated-DNA-protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504586100; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004413070.1 KEGG: ate:Athe_2404 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586101; PFAM: Domain of unknown function (DUF2828) YP_004413071.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: dsy:DSY1392 hypothetical protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504586102; PFAM: Transposase IS200 like YP_004413072.1 COGs: COG3505 Type IV secretory pathway VirD4 protein; InterPro IPR003688; KEGG: dsa:Desal_1688 TraG family protein; PFAM: Ti-type conjugative transfer system, TraG-like; SPTR: Plasmid transfer factor, TraG; IMG reference gene:2504586104; PFAM: TraG/TraD family YP_004413073.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586105 YP_004413074.1 COGs: COG4962 Flp pilus assembly protein ATPase CpaF; InterPro IPR001482; KEGG: ipo:Ilyop_2887 P-type conjugative transfer ATPase TrbB; PFAM: Type II secretion system protein E; SPTR: Conjugal transfer protein TrbB; IMG reference gene:2504586106; PFAM: Type II/IV secretion system protein; TIGRFAM: P-type conjugative transfer ATPase TrbB YP_004413075.1 InterPro IPR007039; PFAM: Conjugal transfer,TrbC; SPTR: Putative conjugal transfer protein; IMG reference gene:2504586107; PFAM: TrbC/VIRB2 family YP_004413076.1 InterPro IPR007792; PFAM: Type IV secretion system, VirB3 / TrbD / AvhB; SPTR: Putative conjugal transfer TrbD transmembrane protein; IMG reference gene:2504586108; PFAM: Type IV secretory pathway, VirB3-like protein YP_004413077.1 COGs: COG3451 Type IV secretory pathway VirB4 protein; InterPro IPR003593; KEGG: gem:GM21_2348 conjugal transfer ATPase TrbE; SMART: ATPase, AAA+ type, core; SPTR: Putative conjugal transfer protein TrbE part 2; IMG reference gene:2504586109; PFAM: FtsK/SpoIIIE family; CagE, TrbE, VirB family, component of type IV transporter system; TIGRFAM: type IV secretion/conjugal transfer ATPase, VirB4 family YP_004413078.1 InterPro IPR012991; KEGG: pna:Pnap_4199 conjugal transfer protein TrbJ; PFAM: Type IV secretion system; SPTR: Putative P-type conjugative transfer protein TrbJ; IMG reference gene:2504586110; TIGRFAM: P-type conjugative transfer protein TrbJ YP_004413079.1 COGs: COG3846 Type IV secretory pathway TrbL protein; InterPro IPR014150:IPR007688; KEGG: gem:GM21_2346 P-type conjugative transfer protein TrbL; PFAM: Conjugal transfer, TrbL/VirB6; SPTR: P-type conjugative transfer protein TrbL; TIGRFAM: Conjugal transfer, TrbL; IMG reference gene:2504586111; PFAM: TrbL/VirB6 plasmid conjugal transfer protein; TIGRFAM: P-type conjugative transfer protein TrbL YP_004413080.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR016047:IPR008258; KEGG: kvu:EIO_1085 transglycosylase SLT domain protein; PFAM: Lytic transglycosylase-like, catalytic; Peptidase M23; SPTR: Transglycosylase SLT domain protein; IMG reference gene:2504586112; PFAM: Transglycosylase SLT domain; TrbL/VirB6 plasmid conjugal transfer protein; Peptidase family M23 YP_004413081.1 COGs: COG4959 Type IV secretory pathway protease TraF; InterPro IPR019533; KEGG: dps:DPPB25 conjugal transfer protein TraF precursor; PFAM: Peptidase S26, conserved region; SPTR: Putative conjugal transfer protein TraF; IMG reference gene:2504586113; PFAM: Peptidase S26 YP_004413082.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586114 YP_004413083.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586115 YP_004413084.1 InterPro IPR001387; KEGG: pth:PTH_1071 transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586116; PFAM: Helix-turn-helix YP_004413085.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR013497:IPR005738:IPR003601:IPR 003602; KEGG: bam:Bamb_6614 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacterial-type; IMG reference gene:2504586117; PFAM: Toprim domain; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid YP_004413086.1 KEGG: tet:TTHERM_00155290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586118 YP_004413087.1 SPTR: Cytochrome c; IMG reference gene:2504586119 YP_004413088.1 COGs: COG2184 Protein involved in cell division; InterPro IPR003812; KEGG: xfn:XfasM23_1067 filamentation induced by cAMP protein Fic; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Toxin-antitoxin system, toxin component, Fic family; IMG reference gene:2504586120; PFAM: Fic/DOC family YP_004413089.1 COGs: COG1961 Site-specific recombinase DNA invertase Pin homologs; InterPro IPR006119:IPR006120; KEGG: bcz:BCZK4228 resolvase family site-specific recombinase; PFAM: Resolvase, N-terminal; Resolvase, helix-turn-helix domain; SMART: Resolvase, N-terminal; SPTR: Site-specific recombinase, resolvase family; IMG reference gene:2504586121; PFAM: Resolvase, N terminal domain YP_004413090.1 IMG reference gene:2504586122 YP_004413091.1 SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504586123 YP_004413092.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586124 YP_004413093.1 SPTR: Putative formate dehydrogenase accessory protein FdhD; IMG reference gene:2504586125 YP_004413094.1 KEGG: llc:LACR_C29 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586126 YP_004413095.1 COGs: COG0350 Methylated DNA-protein cysteine methyltransferase; InterPro IPR014048; KEGG: elm:ELI_2110 methylated-DNA-protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; SPTR: Methylated-DNA--protein-cysteine methyltransferase; TIGRFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding; IMG reference gene:2504586127; PFAM: 6-O-methylguanine DNA methyltransferase, DNA binding domain; TIGRFAM: O-6-methylguanine DNA methyltransferase YP_004413096.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; HAMAP: Hybrid cluster protein; InterPro IPR004137:IPR010048; KEGG: afn:Acfer_0367 hybrid cluster protein; PFAM: Prismane; SPTR: Hydroxylamine reductase; TIGRFAM: Hybrid cluster protein; IMG reference gene:2504586129; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: hydroxylamine reductase YP_004413097.1 SPTR: Conserved domain protein; IMG reference gene:2504586130 YP_004413098.1 COGs: COG2703 Hemerythrin; InterPro IPR012312:IPR012827; KEGG: eel:EUBELI_00442 hemerythrin; PFAM: Haemerythrin/HHE cation-binding motif; SPTR: Putative hemerythrin HHE cation binding domain protein; TIGRFAM: Haemerythrin-like, metal-binding; IMG reference gene:2504586131; PFAM: Hemerythrin HHE cation binding domain; TIGRFAM: hemerythrin-like metal-binding domain YP_004413099.1 COGs: COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase; InterPro IPR003959:IPR003593; KEGG: shi:Shel_24410 recombination factor protein RarA; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: Replication-associated recombination protein A; IMG reference gene:2504586132; PFAM: MgsA AAA+ ATPase C terminal; ATPase family associated with various cellular activities (AAA) YP_004413100.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: gmc:GY4MC1_0706 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504586133; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413101.1 COGs: COG1101 ABC-type uncharacterized transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: afn:Acfer_1633 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504586134; PFAM: ABC transporter YP_004413102.1 COGs: COG4120 ABC-type uncharacterized transport system permease component; InterPro IPR001851; KEGG: afn:Acfer_1634 inner-membrane translocator; PFAM: ABC transporter permease; SPTR: ABC transporter, permease protein; IMG reference gene:2504586135; PFAM: Branched-chain amino acid transport system / permease component YP_004413103.1 COGs: COG2984 ABC-type uncharacterized transport system periplasmic component; InterPro IPR007487; KEGG: afn:Acfer_1636 protein of unknown function DUF534; PFAM: ABC transporter substrate binding protein; SPTR: ABC transporter, substrate-binding protein; IMG reference gene:2504586136; PFAM: ABC transporter substrate binding protein YP_004413104.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR013655:IPR004089:IPR001610; KEGG: bpu:BPUM_3598 sensor histidine kinase; PFAM: PAS fold-3; Chemotaxis methyl-accepting receptor, signalling; SMART: PAC motif; Chemotaxis methyl-accepting receptor, signalling; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504586137; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain; PAS fold; TIGRFAM: PAS domain S-box YP_004413105.1 COGs: COG0834 ABC-type amino acid transport/signal transduction systems periplasmic component/domain; InterPro IPR001638; KEGG: vpr:Vpar_0302 extracellular solute-binding protein family 3; PFAM: Extracellular solute-binding protein, family 3; SMART: Extracellular solute-binding protein, family 3; SPTR: Amino acid ABC transporter, periplasmic amino acid-binding protein; IMG reference gene:2504586138; PFAM: Bacterial extracellular solute-binding proteins, family 3 YP_004413106.1 InterPro IPR006842; KEGG: tde:TDE0975 hypothetical protein; PFAM: Transposase (putative), YhgA-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504586139; PFAM: Putative transposase, YhgA-like YP_004413107.1 COGs: COG0253 Diaminopimelate epimerase; KEGG: ami:Amir_3920 hypothetical protein; SPTR: Putative diaminopimelate epimerase; IMG reference gene:2504586140 YP_004413108.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cst:CLOST_1320 MarR-family transcriptional regulator (transcriptional regulator, MarR family); PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504586141; PFAM: MarR family YP_004413109.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: dat:HRM2_40100 ArcE; PFAM: Secretion protein HlyD; SPTR: Efflux transporter, RND family, MFP subunit; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504586142; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004413110.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036; KEGG: dat:HRM2_40090 ArcD; PFAM: Acriflavin resistance protein; SPTR: RND efflux transporter, hydrophobe/amphiphile efflux-1 family; IMG reference gene:2504586143; PFAM: AcrB/AcrD/AcrF family YP_004413111.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: abu:Abu_0820 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504586144; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004413112.1 InterPro IPR010398; KEGG: ele:Elen_1902 hypothetical protein; PFAM: Protein of unknown function DUF997; SPTR: Putative membrane protein; IMG reference gene:2504586145; PFAM: Protein of unknown function (DUF997) YP_004413113.1 COGs: COG4145 Na+/panthothenate symporter; InterPro IPR001734:IPR011849:IPR019900; KEGG: ele:Elen_1901 sodium/panthothenate symporter; PFAM: Sodium/solute symporter; SPTR: Sodium/pantothenate symporter; TIGRFAM: Sodium/pantothenate symporter; Sodium/solute symporter, subgroup; IMG reference gene:2504586146; PFAM: Sodium:solute symporter family; TIGRFAM: transporter, SSS family; sodium/pantothenate symporter YP_004413114.1 COGs: COG0420 DNA repair exonuclease; InterPro IPR004843:IPR004593; KEGG: slp:Slip_0522 nuclease SbcCD, D subunit; PFAM: Metallo-dependent phosphatase; SPTR: Putative exonuclease SbcD; TIGRFAM: Exonuclease SbcD; IMG reference gene:2504586147; PFAM: Calcineurin-like phosphoesterase; Type 5 capsule protein repressor C terminal; TIGRFAM: exonuclease SbcD YP_004413115.1 COGs: COG0419 ATPase involved in DNA repair; InterPro IPR003395; KEGG: hmo:HM1_1589 exonuclease sbcc, putative; PFAM: RecF/RecN/SMC; SPTR: Putative exonuclease SbcC; IMG reference gene:2504586148; TIGRFAM: exonuclease SbcC YP_004413116.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586149 YP_004413117.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586150 YP_004413118.1 COGs: COG3472 conserved hypothetical protein; InterPro IPR004919:IPR018651; KEGG: mhu:Mhun_2961 hypothetical protein; PFAM: Protein of unknown function DUF2081; Domain of unknown function DUF262; SPTR: Putative uncharacterized protein; IMG reference gene:2504586151; PFAM: Uncharacterized conserved protein (DUF2081); Protein of unknown function DUF262 YP_004413119.1 COGs: COG0286 Type I restriction-modification system methyltransferase subunit; InterPro IPR022749:IPR004546:IPR003356; KEGG: tai:Taci_1545 type I restriction-modification system, M subunit; PFAM: DNA methylase, adenine-specific; N6 adenine-specific DNA methyltransferase, N12 class, N-terminal; PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Type I restriction-modification system, M subunit; TIGRFAM: Restriction endonuclease, type I, EcoRI, M subunit; IMG reference gene:2504586152; PFAM: N-6 DNA Methylase; HsdM N-terminal domain; TIGRFAM: type I restriction system adenine methylase (hsdM) YP_004413120.1 COGs: COG0732 Restriction endonuclease S subunits; InterPro IPR000055; KEGG: hip:CGSHiEE_02145 hypothetical protein; PFAM: Restriction endonuclease, type I, S subunit, EcoBI; SPTR: Putative type I restriction-modification system; IMG reference gene:2504586153; PFAM: Type I restriction modification DNA specificity domain YP_004413121.1 InterPro IPR001387; KEGG: bpb:bpr_I0708 HTH domain-containing protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586155; PFAM: Helix-turn-helix YP_004413122.1 COGs: COG0610 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR007409:IPR006935:IPR004473:IPR014001; KEGG: tai:Taci_1543 type I site-specific deoxyribonuclease, HsdR family; PFAM: Restriction endonuclease, type I, EcoRI, R subunit/Type III, Res subunit, N-terminal; Restriction endonuclease, type I, R subunit/Type III, Res subunit; PRIAM: Type I site-specific deoxyribonuclease; SMART: DEAD-like helicase, N-terminal; SPTR: Type I restriction enzyme r protein; TIGRFAM: Restriction endonuclease, type I, EcoRI, R subunit; IMG reference gene:2504586156; PFAM: Type I restriction enzyme R protein N terminus (HSDR_N); Type I restriction and modification enzyme - subunit R C terminal; Type III restriction enzyme, res subunit; TIGRFAM: type I site-specific deoxyribonuclease, HsdR family YP_004413123.1 COGs: COG0422 Thiamine biosynthesis protein ThiC; HAMAP: Thiamine biosynthesis protein ThiC; InterPro IPR002817; KEGG: afn:Acfer_0488 thiamine biosynthesis protein ThiC; PFAM: Thiamine biosynthesis protein ThiC; SPTR: Phosphomethylpyrimidine synthase; TIGRFAM: Thiamine biosynthesis protein ThiC; IMG reference gene:2504586157; PFAM: ThiC family; TIGRFAM: thiamine biosynthesis protein ThiC YP_004413124.1 IMG reference gene:2504586158 YP_004413125.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: dhd:Dhaf_2112 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504586159; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413126.1 COGs: COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); InterPro IPR008331; KEGG: lba:Lebu_1926 ferritin Dps family protein; PFAM: Ferritin/Dps protein; SPTR: Antigen TpF1; IMG reference gene:2504586160; PFAM: Ferritin-like domain YP_004413127.1 COGs: COG1968 Uncharacterized bacitracin resistance protein; HAMAP: Bacitracin resistance protein BacA; InterPro IPR003824; KEGG: aoe:Clos_0946 putative undecaprenol kinase; PFAM: Bacitracin resistance protein BacA; SPTR: Undecaprenyl-diphosphatase; TIGRFAM: Bacitracin resistance protein BacA; IMG reference gene:2504586161; PFAM: Bacitracin resistance protein BacA; TIGRFAM: undecaprenyl-diphosphatase UppP YP_004413128.1 COGs: COG0708 Exonuclease III; InterPro IPR000097:IPR005135:IPR004808; KEGG: vpr:Vpar_1553 exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Exodeoxyribonuclease III; TIGRFAM: AP endonuclease, family 1; Exodeoxyribonuclease III xth; IMG reference gene:2504586162; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth) YP_004413129.1 KEGG: cha:CHAB381_0064 modification methylase EcoRI (adenine-specificmethyltransferase EcoRI) (M.EcoRI); PRIAM: Site-specific DNA-methyltransferase (adenine-specific); SPTR: Adenine-specific DNA modification methylase; IMG reference gene:2504586163 YP_004413130.1 InterPro IPR003615:IPR004919:IPR002711; KEGG: blt:Balat_1446 hypothetical protein; PFAM: Domain of unknown function DUF262; HNH endonuclease; SMART: HNH nuclease; SPTR: Putative HNH endonuclease domain protein; IMG reference gene:2504586165; PFAM: HNH endonuclease; Protein of unknown function DUF262 YP_004413131.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: bln:Blon_0026 ATPase (AAA+ superfamily)-like protein; SPTR: ATPase; IMG reference gene:2504586166 YP_004413132.1 COGs: COG0234 Co-chaperonin GroES (HSP10); InterPro IPR020818; KEGG: gtn:GTNG_0222 co-chaperonin GroES; PFAM: Chaperonin Cpn10; SMART: Chaperonin Cpn10; SPTR: 10 kDa chaperonin; IMG reference gene:2504586167; PFAM: Chaperonin 10 Kd subunit YP_004413133.1 COGs: COG0459 Chaperonin GroEL (HSP60 family); InterPro IPR001844:IPR002423; KEGG: vpr:Vpar_1034 chaperonin GroEL; PFAM: Chaperonin Cpn60/TCP-1; SPTR: 60 kDa chaperonin; TIGRFAM: Chaperonin Cpn60; IMG reference gene:2504586168; PFAM: TCP-1/cpn60 chaperonin family; TIGRFAM: chaperonin GroL YP_004413134.1 COGs: COG4149 ABC-type molybdate transport system permease component; InterPro IPR011867:IPR000515; KEGG: bhy:BHWA1_00530 ModC, ABC-type molybdate transport system, permease component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Molybdate ABC transporter, permease protein; TIGRFAM: Molybdate ABC transporter, permease protein; IMG reference gene:2504586169; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: molybdate ABC transporter, permease protein YP_004413135.1 COGs: COG1118 ABC-type sulfate/molybdate transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: apv:Apar_0256 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Molybdate ABC transporter, permease protein; IMG reference gene:2504586170; PFAM: ABC transporter YP_004413136.1 COGs: COG0725 ABC-type molybdate transport system periplasmic component; InterPro IPR006059:IPR005950; KEGG: ckr:CKR_2732 hypothetical protein; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Molybdate ABC transporter, periplasmic molybdate-binding protein; TIGRFAM: Molybdenum ABC transporter, periplasmic binding protein; IMG reference gene:2504586171; PFAM: Bacterial extracellular solute-binding protein; TIGRFAM: molybdenum ABC transporter, periplasmic molybdate-binding protein YP_004413137.1 COGs: COG5013 Nitrate reductase alpha subunit; InterPro IPR006468:IPR006963:IPR006657:IPR006656; KEGG: vpr:Vpar_0222 nitrate reductase, alpha subunit; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide-binding domain; PRIAM: Nitrate reductase; SMART: Molybdopterin oxidoreductase, Fe4S4 domain; SPTR: Nitrate reductase, alpha subunit; TIGRFAM: Nitrate reductase, alpha subunit; IMG reference gene:2504586172; PFAM: Molybdopterin oxidoreductase; Molydopterin dinucleotide binding domain; TIGRFAM: respiratory nitrate reductase, alpha subunit YP_004413138.1 COGs: COG1140 Nitrate reductase beta subunit; InterPro IPR006547; KEGG: vpr:Vpar_0223 nitrate reductase, beta subunit; PRIAM: Nitrate reductase; SPTR: Nitrate reductase, beta subunit; TIGRFAM: Nitrate reductase, beta subunit; IMG reference gene:2504586173; TIGRFAM: nitrate reductase, beta subunit YP_004413139.1 COGs: COG2180 Nitrate reductase delta subunit; InterPro IPR003765:IPR020945; KEGG: vpr:Vpar_0224 nitrate reductase molybdenum cofactor assembly chaperone; PFAM: DMSO/Nitrate reductase chaperone; SPTR: Nitrate reductase molybdenum cofactor assembly chaperone; TIGRFAM: Nitrate reductase chaperone, NarJ; IMG reference gene:2504586174; PFAM: Nitrate reductase delta subunit; TIGRFAM: nitrate reductase molybdenum cofactor assembly chaperone YP_004413140.1 COGs: COG2181 Nitrate reductase gamma subunit; InterPro IPR003816; KEGG: vpr:Vpar_0225 respiratory nitrate reductase, gamma subunit; PFAM: Nitrate reductase, gamma subunit; PRIAM: Nitrate reductase; SPTR: Respiratory nitrate reductase, gamma subunit; TIGRFAM: Nitrate reductase, gamma subunit; IMG reference gene:2504586175; PFAM: Nitrate reductase gamma subunit; TIGRFAM: respiratory nitrate reductase, gamma subunit YP_004413141.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR001453; KEGG: csh:Closa_1040 molybdopterin binding domain protein; PFAM: Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Molybdopterin-binding domain protein; IMG reference gene:2504586176; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain YP_004413142.1 COGs: COG0303 Molybdopterin biosynthesis enzyme; InterPro IPR005110:IPR005111:IPR001453:IPR020817; KEGG: aoe:Clos_0210 molybdenum cofactor synthesis domain-containing protein; PFAM: MoeA, N-terminal and linker domain; MoeA, C-terminal, domain IV; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: Molybdopterin biosynthesis MoeA protein; TIGRFAM: Molybdenum cofactor synthesis; IMG reference gene:2504586177; PFAM: Probable molybdopterin binding domain; MoeA N-terminal region (domain I and II); MoeA C-terminal region (domain IV); TIGRFAM: molybdenum cofactor synthesis domain YP_004413143.1 COGs: COG2896 Molybdenum cofactor biosynthesis protein; InterPro IPR007197:IPR010505:IPR013483:IPR006638; KEGG: cbe:Cbei_1989 molybdenum cofactor biosynthesis protein A; PFAM: Radical SAM; Molybdenum cofactor synthesis C-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: Molybdenum cofactor biosynthesis protein A; TIGRFAM: Molybdenum cofactor biosynthesis protein A; IMG reference gene:2504586178; PFAM: Molybdenum Cofactor Synthesis C; Radical SAM superfamily; TIGRFAM: molybdenum cofactor biosynthesis protein A, bacterial YP_004413144.1 COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR005302:IPR001453:IPR020817; KEGG: cpy:Cphy_1481 molybdenum cofactor synthesis domain-containing protein; PFAM: Molybdopterin binding; Molybdenum cofactor sulfurase, C-terminal; SMART: Molybdopterin binding; SPTR: Molybdenum cofactor biosynthesis protein B; TIGRFAM: Molybdenum cofactor synthesis; IMG reference gene:2504586179; PFAM: Probable molybdopterin binding domain; MOSC domain; TIGRFAM: molybdenum cofactor synthesis domain YP_004413145.1 COGs: COG0746 Molybdopterin-guanine dinucleotide biosynthesis protein A; HAMAP: Molybdopterin-guanine dinucleotide biosynthesis protein A; InterPro IPR004435:IPR013482; KEGG: vpr:Vpar_1299 molybdopterin-guanine dinucleotide biosynthesis protein; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein MobB; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB), conserved domain; IMG reference gene:2504586180; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB YP_004413146.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: ckr:CKR_1462 hypothetical protein; PFAM: Methyltransferase type 11; SPTR: Methlytransferase, UbiE/COQ5 family; IMG reference gene:2504586181; PFAM: Methyltransferase domain YP_004413147.1 COGs: COG2223 Nitrate/nitrite transporter; InterPro IPR011701; KEGG: vpr:Vpar_0220 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Nitrate/nitrite transporter; IMG reference gene:2504586182; PFAM: Major Facilitator Superfamily YP_004413148.1 COGs: COG0315 Molybdenum cofactor biosynthesis enzyme; InterPro IPR002820:IPR023045; KEGG: cbt:CLH_1100 molybdenum cofactor biosynthesis protein C; PFAM: Molybdopterin cofactor biosynthesis C (MoaC) domain; SPTR: Molybdenum cofactor biosynthesis protein C; TIGRFAM: Molybdenum cofactor biosynthesis C; IMG reference gene:2504586183; PFAM: MoaC family; TIGRFAM: molybdenum cofactor biosynthesis protein MoaC YP_004413149.1 KEGG: ere:EUBREC_2192 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586184; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413150.1 COGs: COG4760 membrane protein; KEGG: xop:PXO_02484 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2504586185 YP_004413151.1 COGs: COG0449 Glucosamine 6-phosphate synthetase contains amidotransferase and phosphosugar isomerase domains; InterPro IPR001347:IPR005855:IPR000583; KEGG: afn:Acfer_0925 glucosamine/fructose-6-phosphate aminotransferase, isomerizing; PFAM: Sugar isomerase (SIS); Glutamine amidotransferase, class-II; PRIAM: Glutamine--fructose-6-phosphate transaminase (isomerizing); SPTR: Glutamine-fructose-6-phosphate transaminase; TIGRFAM: Glucosamine-fructose-6-phosphate aminotransferase, isomerising; IMG reference gene:2504586186; PFAM: SIS domain; Glutamine amidotransferases class-II; TIGRFAM: glucosamine--fructose-6-phosphate aminotransferase (isomerizing) YP_004413152.1 COGs: COG0516 IMP dehydrogenase/GMP reductase; InterPro IPR000644:IPR001093; KEGG: cbe:Cbei_2114 inosine 5-monophosphate dehydrogenase; PFAM: IMP dehydrogenase/GMP reductase; Cystathionine beta-synthase, core; PRIAM: IMP dehydrogenase; SPTR: Inosine-5'-monophosphate dehydrogenase; IMG reference gene:2504586187; PFAM: CBS domain; IMP dehydrogenase / GMP reductase domain; TIGRFAM: inosine-5'-monophosphate dehydrogenase YP_004413153.1 InterPro IPR014948; KEGG: dsy:DSY0675 hypothetical protein; PFAM: Protein of unknown function DUF1819, putative inner membrane; SPTR: Putative inner membrane protein DUF1819; IMG reference gene:2504586188; PFAM: Putative inner membrane protein (DUF1819) YP_004413154.1 InterPro IPR014858; KEGG: esi:Exig_0313 hypothetical protein; PFAM: Protein of unknown function DUF1788; SPTR: Putative cytoplasmic protein; IMG reference gene:2504586189; PFAM: Domain of unknown function (DUF1788) YP_004413155.1 KEGG: dsy:DSY0676 hypothetical protein; SPTR: Putative ATPase; IMG reference gene:2504586190 YP_004413156.1 InterPro IPR003356; KEGG: chy:CHY_2653 putative restriction enzyme; PFAM: DNA methylase, adenine-specific; SPTR: Putative restriction enzyme; IMG reference gene:2504586191; PFAM: N-6 DNA Methylase YP_004413157.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421; KEGG: sar:SAR2299 hypothetical protein; PFAM: ATPase, AAA-4; SPTR: Toxin-antitoxin system, toxin component, Fic family; IMG reference gene:2504586192; PFAM: Divergent AAA domain YP_004413158.1 InterPro IPR014060:IPR013973; KEGG: dsy:DSY0679 hypothetical protein; PFAM: PglZ domain; SPTR: Putative cytoplasmic protein; TIGRFAM: Conserved hypothetical protein CHP02687; IMG reference gene:2504586193; PFAM: PglZ domain; TIGRFAM: TIGR02687 family protein YP_004413159.1 COGs: COG0261 Ribosomal protein L21; InterPro IPR001787; KEGG: vpr:Vpar_1217 ribosomal protein L21; PFAM: Ribosomal protein L21; SPTR: 50S ribosomal protein L21; TIGRFAM: Ribosomal protein L21; IMG reference gene:2504586195; PFAM: Ribosomal prokaryotic L21 protein; TIGRFAM: ribosomal protein L21 YP_004413160.1 COGs: COG2868 ribosomal protein; InterPro IPR007422; KEGG: aar:Acear_0569 protein of unknown function DUF464; PFAM: Protein of unknown function DUF464; SPTR: Putative ribosomal protein; IMG reference gene:2504586196; PFAM: Protein of unknown function (DUF464) YP_004413161.1 COGs: COG0211 Ribosomal protein L27; InterPro IPR001684; KEGG: vpr:Vpar_1215 ribosomal protein L27; PFAM: Ribosomal protein L27; SPTR: 50S ribosomal protein L27; TIGRFAM: Ribosomal protein L27; IMG reference gene:2504586197; PFAM: Ribosomal L27 protein; TIGRFAM: ribosomal protein L27 YP_004413162.1 COGs: COG0536 GTPase; InterProIPR014100:IPR006169:IPR002917:IPR005225:IPR 015349; KEGG: afn:Acfer_0227 GTP-binding protein Obg/CgtA; PFAM: GTP1/OBG subdomain; GTP-binding protein, HSR1-related; GTP-binding protein GTP1/OBG, C-terminal; SPTR: GTPase obg; TIGRFAM: GTP-binding protein Obg/CgtA; Small GTP-binding protein; GTP-binding protein GTP1/OBG, C-terminal; IMG reference gene:2504586198; PFAM: GTPase of unknown function; GTP1/OBG; Domain of unknown function (DUF1967); TIGRFAM: Obg family GTPase CgtA; Obg family GTPase CgtA, C-terminal extension; small GTP-binding protein domain YP_004413163.1 COGs: COG0263 Glutamate 5-kinase; InterPro IPR001048:IPR002478:IPR005715; KEGG: afn:Acfer_0228 glutamate 5-kinase; PFAM: Aspartate/glutamate/uridylate kinase; Pseudouridine synthase/archaeosine transglycosylase; SMART: Pseudouridine synthase/archaeosine transglycosylase; SPTR: Glutamate 5-kinase; TIGRFAM: Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase; IMG reference gene:2504586199; PFAM: Amino acid kinase family; PUA domain; TIGRFAM: glutamate 5-kinase YP_004413164.1 COGs: COG0014 Gamma-glutamyl phosphate reductase; InterPro IPR000965:IPR015590; KEGG: tte:TTE1278 gamma-glutamyl phosphate reductase; PFAM: Aldehyde dehydrogenase domain; PRIAM: Glutamate-5-semialdehyde dehydrogenase; SPTR: Gamma-glutamyl phosphate reductase; TIGRFAM: Gamma-glutamyl phosphate reductase GPR; IMG reference gene:2504586200; PFAM: Aldehyde dehydrogenase family; TIGRFAM: gamma-glutamyl phosphate reductase YP_004413165.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586201 YP_004413166.1 COGs: COG1057 Nicotinic acid mononucleotide adenylyltransferase; HAMAP: Probable nicotinate-nucleotide adenylyltransferase; InterPro IPR004820:IPR004821:IPR005248; KEGG: dau:Daud_1868 nicotinic acid mononucleotide adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Nicotinate-nucleotide adenylyltransferase; SPTR: Probable nicotinate-nucleotide adenylyltransferase; TIGRFAM: Probable nicotinate-nucleotide adenylyltransferase; Cytidyltransferase-related; IMG reference gene:2504586202; PFAM: Cytidylyltransferase; TIGRFAM: nicotinate (nicotinamide) nucleotide adenylyltransferase; cytidyltransferase-related domain YP_004413167.1 COGs: COG1713 HD superfamily hydrolase involved in NAD metabolism; InterPro IPR005249:IPR003607:IPR006675:IPR006674; KEGG: tte:TTE0919 HD superfamily hydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: HD domain protein; TIGRFAM: Conserved hypothetical protein CHP00488; Uncharacterised protein family HDIG; IMG reference gene:2504586203; PFAM: HD domain; TIGRFAM: putative HD superfamily hydrolase of NAD metabolism; uncharacterized domain HDIG YP_004413168.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: afn:Acfer_0144 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Putative cell envelope-related function transcriptional attenuator; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504586204; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004413169.1 COGs: COG0799 Iojap protein; InterPro IPR004394; KEGG: afn:Acfer_0145 iojap-like protein; PFAM: Ribosome-associated, Iojap-like; SPTR: Iojap-like protein; TIGRFAM: Ribosome-associated, Iojap-like; IMG reference gene:2504586205; PFAM: Domain of unknown function DUF143; TIGRFAM: iojap-like ribosome-associated protein YP_004413170.1 COGs: COG2996 conserved hypothetical protein; InterPro IPR022967; KEGG: vpr:Vpar_0819 RNA binding S1 domain protein; SPTR: Nucleic acid-binding protein YitL; IMG reference gene:2504586206 YP_004413171.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR001789:IPR002545; KEGG: afl:Aflv_1927 chemotaxis protein CheV (CheW-REC domains); PFAM: CheW-like protein; Signal transduction response regulator, receiver domain; SMART: CheW-like protein; Signal transduction response regulator, receiver domain; SPTR: Chemotaxis protein CheV; IMG reference gene:2504586207; PFAM: CheW-like domain; Response regulator receiver domain YP_004413172.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504586208 YP_004413173.1 COGs: COG0102 Ribosomal protein L13; InterPro IPR005823:IPR005822; KEGG: vpr:Vpar_1450 ribosomal protein L13; PFAM: Ribosomal protein L13; SPTR: 50S ribosomal protein L13; TIGRFAM: Ribosomal protein L13, bacterial-type; IMG reference gene:2504586211; PFAM: Ribosomal protein L13; TIGRFAM: ribosomal protein L13, bacterial type YP_004413174.1 COGs: COG0103 Ribosomal protein S9; InterPro IPR000754; KEGG: vpr:Vpar_1449 ribosomal protein S9; PFAM: Ribosomal protein S9; SPTR: 30S ribosomal protein S9; IMG reference gene:2504586212; PFAM: Ribosomal protein S9/S16 YP_004413175.1 KEGG: afn:Acfer_1042 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586213 YP_004413176.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: afn:Acfer_0798 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504586214; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_004413177.1 COGs: COG0737 5'-nucleotidase/2' 3'-cyclic phosphodiesterase and related esterase; InterPro IPR008334:IPR004843; KEGG: afn:Acfer_0834 5'-nucleotidase domain protein; PFAM: 5'-Nucleotidase, C-terminal; Metallo-dependent phosphatase; PRIAM: 5'-nucleotidase; SPTR: 5'-nucleotidase family protein; IMG reference gene:2504586215; PFAM: 5'-nucleotidase, C-terminal domain; Calcineurin-like phosphoesterase YP_004413178.1 COGs: COG2385 Sporulation protein and related protein; InterPro IPR013693:IPR013486; KEGG: vpr:Vpar_0593 SpoIID/LytB domain protein; PFAM: Sporulation stage II protein D, amidase enhancer LytB N-terminal; SPTR: SpoIID/LytB domain protein; TIGRFAM: Sporulation stage II protein D, amidase enhancer LytB; IMG reference gene:2504586216; PFAM: Stage II sporulation protein; TIGRFAM: SpoIID/LytB domain YP_004413179.1 COGs: COG0809 S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase); InterPro IPR003699; KEGG: afn:Acfer_1526 S-adenosylmethionine/tRNA-ribosyltransferase-isomerase; PFAM: Queuosine biosynthesis protein; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; TIGRFAM: Queuosine biosynthesis protein; IMG reference gene:2504586217; PFAM: Queuosine biosynthesis protein; TIGRFAM: S-adenosylmethionine:tRNA ribosyltransferase-isomerase YP_004413180.1 COGs: COG0343 Queuine/archaeosine tRNA-ribosyltransferase; HAMAP: Queuine tRNA-ribosyltransferase; InterPro IPR002616:IPR004803; KEGG: pth:PTH_1032 queuine tRNA-ribosyltransferase; PFAM: Queuine/other tRNA-ribosyltransferase; PRIAM: tRNA-guanine transglycosylase; SPTR: Queuine tRNA-ribosyltransferase; TIGRFAM: Queuine tRNA-ribosyltransferase; Queuine/other tRNA-ribosyltransferase; IMG reference gene:2504586218; PFAM: Queuine tRNA-ribosyltransferase; TIGRFAM: tRNA-guanine transglycosylases, various specificities; tRNA-guanine transglycosylase, queuosine-34-forming YP_004413181.1 COGs: COG1862 Preprotein translocase subunit YajC; InterPro IPR003849; KEGG: nth:Nther_1790 preprotein translocase, YajC subunit; PFAM: Preprotein translocase YajC; SPTR: Preprotein translocase, YajC subunit; TIGRFAM: Preprotein translocase YajC; IMG reference gene:2504586219; PFAM: Preprotein translocase subunit; TIGRFAM: preprotein translocase, YajC subunit YP_004413182.1 COGs: COG0212 5-formyltetrahydrofolate cyclo-ligase; InterPro IPR002698; KEGG: toc:Toce_0352 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; SPTR: 5-formyltetrahydrofolate cyclo-ligase; TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; IMG reference gene:2504586220; PFAM: 5-formyltetrahydrofolate cyclo-ligase family; TIGRFAM: 5,10-methenyltetrahydrofolate synthetase YP_004413183.1 COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR010822:IPR001932; KEGG: nth:Nther_1283 protein serine/threonine phosphatase; PFAM: Sporulation stage II, protein E C-terminal; SMART: Protein phosphatase 2C-like; SPTR: Putative stage II sporulation protein E; IMG reference gene:2504586221; PFAM: Stage II sporulation protein E (SpoIIE) YP_004413184.1 KEGG: nth:Nther_1284 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586222 YP_004413185.1 COGs: COG0342 Preprotein translocase subunit SecD; InterPro IPR022646:IPR022813:IPR005791:IPR022645; KEGG: afn:Acfer_1522 protein-export membrane protein SecD; PFAM: Preprotein translocase, SecD/SecF/SecDF; SecD/SecF/SecDF export membrane protein, GG motif, N-terminal; SPTR: Protein-export membrane protein SecD; TIGRFAM: SecD export membrane protein; SecD/SecF/SecDF export membrane protein, bacteria; IMG reference gene:2504586223; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein SecD; protein-export membrane protein, SecD/SecF family YP_004413186.1 COGs: COG0341 Preprotein translocase subunit SecF; InterPro IPR005665:IPR022646:IPR022813:IPR022645; KEGG: dae:Dtox_1124 preprotein translocase subunit SecF; PFAM: Preprotein translocase, SecD/SecF/SecDF; SecD/SecF/SecDF export membrane protein, GG motif, N-terminal; SPTR: Protein-export membrane protein SecF; TIGRFAM: SecF protein; SecD/SecF/SecDF export membrane protein, bacteria; IMG reference gene:2504586224; PFAM: Protein export membrane protein; SecD/SecF GG Motif; TIGRFAM: protein-export membrane protein, SecD/SecF family; protein-export membrane protein SecF YP_004413187.1 COGs: COG0608 Single-stranded DNA-specific exonuclease; InterPro IPR003156:IPR001667:IPR004610; KEGG: hor:Hore_12210 single-stranded-DNA-specific exonuclease RecJ; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Single-stranded-DNA-specific exonuclease RecJ; TIGRFAM: Bacterial RecJ exonuclease; IMG reference gene:2504586225; PFAM: DHH family; DHHA1 domain; TIGRFAM: single-stranded-DNA-specific exonuclease RecJ YP_004413188.1 COGs: COG0317 Guanosine polyphosphate pyrophosphohydrolase/synthetase; InterProIPR006674:IPR007685:IPR004095:IPR002912:IPR 004811:IPR003607; KEGG: afn:Acfer_1517 (p)ppGpp synthetase I, SpoT/RelA; PFAM: RelA/SpoT; Metal-dependent phosphohydrolase, HD subdomain; TGS; Amino acid-binding ACT; PRIAM: GTP diphosphokinase; SMART: RelA/SpoT; Metal-dependent phosphohydrolase, HD domain; SPTR: GTP diphosphokinase; TIGRFAM: RelA/SpoT protein; IMG reference gene:2504586226; PFAM: HD domain; Region found in RelA / SpoT proteins; TGS domain; TIGRFAM: (p)ppGpp synthetase, RelA/SpoT family YP_004413189.1 COGs: COG0491 Zn-dependent hydrolase including glyoxylase; InterPro IPR001279; KEGG: tjr:TherJR_1208 hydroxyacylglutathione hydrolase; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504586227; PFAM: Metallo-beta-lactamase superfamily YP_004413190.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tjr:TherJR_1326 ferric uptake regulator, Fur family; PFAM: Ferric-uptake regulator; SPTR: Ferric uptake regulator; IMG reference gene:2504586228; PFAM: Ferric uptake regulator family YP_004413191.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cth:Cthe_1341 coproporphyrinogen III oxidase; PFAM: Radical SAM; PRIAM: Coproporphyrinogen dehydrogenase; SMART: Elongator protein 3/MiaB/NifB; SPTR: Coproporphyrinogen oxidase, anaerobic; IMG reference gene:2504586229; PFAM: Radical SAM superfamily; TIGRFAM: coproporphyrinogen dehydrogenase HemZ YP_004413192.1 COGs: COG0124 Histidyl-tRNA synthetase; HAMAP: Histidyl-tRNA synthetase, class IIa, subgroup; InterPro IPR002314:IPR004154:IPR015807; KEGG: afn:Acfer_1513 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Anticodon-binding; PRIAM: Histidine--tRNA ligase; SPTR: Histidyl-tRNA synthetase; TIGRFAM: Histidyl-tRNA synthetase, class IIa, subgroup; IMG reference gene:2504586230; PFAM: Anticodon binding domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: histidyl-tRNA synthetase YP_004413193.1 COGs: COG0173 Aspartyl-tRNA synthetase; InterPro IPR004115:IPR004365:IPR004524:IPR004364; KEGG: vpr:Vpar_1207 aspartyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); GAD domain; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Aspartate--tRNA ligase; SPTR: Aspartyl-tRNA synthetase; TIGRFAM: Aspartyl-tRNA synthetase, class IIb, bacterial/mitochondrial type; IMG reference gene:2504586231; PFAM: GAD domain; tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: aspartyl-tRNA synthetase, bacterial type YP_004413194.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586232 YP_004413195.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089; KEGG: cbi:CLJ_B0457 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein signaling domain protein; IMG reference gene:2504586233; PFAM: HAMP domain; Cache domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413196.1 InterPro IPR001705; KEGG: vpr:Vpar_1512 ribosomal protein L33; PFAM: Ribosomal protein L33; SPTR: 50S ribosomal protein L33; TIGRFAM: Ribosomal protein L33; IMG reference gene:2504586234; PFAM: Ribosomal protein L33; TIGRFAM: ribosomal protein L33, bacterial type YP_004413197.1 InterPro IPR005807:IPR001901; KEGG: toc:Toce_2105 preprotein translocase, SecE subunit; PFAM: Protein SecE/Sec61-gamma protein; SPTR: Preprotein translocase, SecE subunit; TIGRFAM: SecE subunit of protein translocation complex; manually curated; IMG reference gene:2504586235; PFAM: SecE/Sec61-gamma subunits of protein translocation complex; TIGRFAM: preprotein translocase, SecE subunit, bacterial YP_004413198.1 COGs: COG0250 Transcription antiterminator; InterPro IPR001062:IPR005824:IPR006645; KEGG: tjr:TherJR_0282 NusG antitermination factor; PFAM: Transcription antitermination protein, NusG, N-terminal; KOW; SMART: Transcription antitermination protein, NusG, N-terminal; KOW; SPTR: Transcription antitermination protein nusG; TIGRFAM: Transcription antitermination protein, NusG; IMG reference gene:2504586236; PFAM: Transcription termination factor nusG; KOW motif; TIGRFAM: transcription termination/antitermination factor NusG YP_004413199.1 COGs: COG0080 Ribosomal protein L11; InterPro IPR006519:IPR000911:IPR020783:IPR020784; KEGG: pth:PTH_0306 50S ribosomal protein L11; PFAM: Ribosomal protein L11, N-terminal domain; Ribosomal protein L11, C-terminal domain; SMART: Ribosomal protein L11; SPTR: 50S ribosomal protein L11; TIGRFAM: Ribosomal protein L11, bacterial-type; IMG reference gene:2504586237; PFAM: Ribosomal protein L11, RNA binding domain; Ribosomal protein L11, N-terminal domain; TIGRFAM: 50S ribosomal protein L11 YP_004413200.1 COGs: COG0081 Ribosomal protein L1; InterPro IPR005878:IPR002143; KEGG: afn:Acfer_0261 ribosomal protein L1; PFAM: Ribosomal protein L1; SPTR: 50S ribosomal protein L1; TIGRFAM: Ribosomal protein L1, bacterial-type; IMG reference gene:2504586238; PFAM: Ribosomal protein L1p/L10e family; TIGRFAM: ribosomal protein L1, bacterial/chloroplast YP_004413201.1 COGs: COG0244 Ribosomal protein L10; InterPro IPR001790; KEGG: afn:Acfer_0262 ribosomal protein L10; PFAM: Ribosomal protein L10/acidic P0; SPTR: 50S ribosomal protein L10; IMG reference gene:2504586239; PFAM: Ribosomal protein L10 YP_004413202.1 COGs: COG0222 Ribosomal protein L7/L12; InterPro IPR000206:IPR013823; KEGG: drm:Dred_0206 50S ribosomal protein L7/L12; PFAM: Ribosomal protein L7/L12, C-terminal; SPTR: 50S ribosomal protein L7/L12; TIGRFAM: Ribosomal protein L7/L12; IMG reference gene:2504586240; PFAM: Ribosomal protein L7/L12 C-terminal domain; TIGRFAM: ribosomal protein L7/L12 YP_004413203.1 COGs: COG2271 Sugar phosphate permease; InterPro IPR011701; KEGG: vpr:Vpar_1394 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator family transporter; IMG reference gene:2504586241; PFAM: Major Facilitator Superfamily YP_004413204.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586242 YP_004413205.1 COGs: COG1329 Transcriptional regulators similar to M. xanthus CarD; InterPro IPR003711; KEGG: tjr:TherJR_0251 transcriptional regulator, CarD family; PFAM: Transcription factor CarD; SPTR: Transcriptional regulator, CarD family; IMG reference gene:2504586243; PFAM: CarD-like/TRCF domain YP_004413206.1 COGs: COG4956 Integral membrane protein (PIN domain superfamily); InterPro IPR002716:IPR002792:IPR006596; KEGG: ttm:Tthe_0403 PilT protein domain protein; PFAM: PilT protein, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Nucleotide binding protein, PINc; SPTR: PIN/TRAM domain protein; IMG reference gene:2504586244; PFAM: TRAM domain; PIN domain YP_004413207.1 COGs: COG1211 4-diphosphocytidyl-2-methyl-D-erithritol synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; InterPro IPR001228; KEGG: tjr:TherJR_0253 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; PFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; SPTR: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; IMG reference gene:2504586245; PFAM: Uncharacterized protein family UPF0007; TIGRFAM: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_004413208.1 COGs: COG0245 2C-methyl-D-erythritol 2 4-cyclodiphosphate synthase; InterPro IPR003526; KEGG: gbm:Gbem_3798 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; PFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; SPTR: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, core; IMG reference gene:2504586246; PFAM: YgbB family; TIGRFAM: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_004413209.1 COGs: COG0215 Cysteinyl-tRNA synthetase; InterPro IPR015803:IPR015273; KEGG: vpr:Vpar_1015 cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase, class Ia; Cysteinyl-tRNA synthetase, class Ia, DALR; PRIAM: Cysteine--tRNA ligase; SMART: Cysteinyl-tRNA synthetase, class Ia, DALR; SPTR: Cysteinyl-tRNA synthetase; TIGRFAM: Cysteinyl-tRNA synthetase, class Ia; IMG reference gene:2504586247; PFAM: tRNA synthetases class I (C) catalytic domain; DALR domain; TIGRFAM: cysteinyl-tRNA synthetase YP_004413210.1 COGs: COG1939 conserved hypothetical protein; InterPro IPR000999; KEGG: afn:Acfer_0722 ribonuclease III; PFAM: Ribonuclease III; SPTR: RNase3 domain protein; IMG reference gene:2504586248; PFAM: RNase3 domain YP_004413211.1 COGs: COG1351 alternative thymidylate synthase; InterPro IPR003669; KEGG: bai:BAA_3835 prophage LambdaBa01, thymidylate synthase-complementing protein; PFAM: Thymidylate synthase ThyX; PRIAM: Thymidylate synthase (FAD); SPTR: Thymidylate synthase thyX; TIGRFAM: Thymidylate synthase ThyX; IMG reference gene:2504586249; PFAM: Thymidylate synthase complementing protein; TIGRFAM: thymidylate synthase, flavin-dependent YP_004413212.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537:IPR004441; KEGG: afn:Acfer_0251 RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase TrmH, group 3; IMG reference gene:2504586250; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding; TIGRFAM: rRNA methylase, putative, group 3 YP_004413213.1 COGs: COG3688 RNA-binding protein containing a PIN domain; InterPro IPR010298; KEGG: amt:Amet_4496 hypothetical protein; PFAM: Protein of unknown function DUF901; SPTR: Putative tetracycline resistance protein; IMG reference gene:2504586251; PFAM: Protein of unknown function (DUF901) YP_004413214.1 COGs: COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog; InterPro IPR007627:IPR013249:IPR014218:IPR014284; KEGG: hmo:HM1_1361 RNA polymerase factor sigma-70; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma factor 70, region 4 type 2; SPTR: RNA polymerase sigma-H factor; TIGRFAM: RNA polymerase sigma-H type; RNA polymerase sigma-70; IMG reference gene:2504586252; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma-H factor YP_004413215.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586253 YP_004413216.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200; KEGG: cbe:Cbei_2524 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: Putative hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504586254; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004413217.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR001279; KEGG: vpr:Vpar_1045 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504586255; PFAM: Metallo-beta-lactamase superfamily YP_004413218.1 InterPro IPR021377; PFAM: Protein of unknown function DUF3006; SPTR: Putative uncharacterized protein; IMG reference gene:2504586256; PFAM: Protein of unknown function (DUF3006) YP_004413219.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: vpr:Vpar_1044 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504586257; PFAM: N-acetylmuramoyl-L-alanine amidase; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD YP_004413220.1 COGs: COG5401 Spore germination protein; InterPro IPR019606; KEGG: tjr:TherJR_2573 lipoprotein LpqB, GerMN domain protein; PFAM: GerMN domain; SMART: GerMN domain; SPTR: Putative lipoprotein; IMG reference gene:2504586258; PFAM: Sporulation and spore germination YP_004413221.1 InterPro IPR007337; KEGG: lba:Lebu_0151 addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504586259; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004413222.1 KEGG: cpv:cgd4_200 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586260 YP_004413223.1 COGs: COG0591 Na+/proline symporter; InterPro IPR001734:IPR011851:IPR019900; KEGG: vpr:Vpar_1387 sodium/proline symporter; PFAM: Sodium/solute symporter; SPTR: Sodium/proline symporter; TIGRFAM: Sodium/proline symporter; Sodium/solute symporter, subgroup; IMG reference gene:2504586261; PFAM: Sodium:solute symporter family; TIGRFAM: sodium/proline symporter; transporter, SSS family YP_004413224.1 InterPro IPR001387; PFAM: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586263; PFAM: Helix-turn-helix YP_004413225.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR006076; KEGG: hmo:HM1_1957 fad dependent oxidoreductase, putative; PFAM: FAD dependent oxidoreductase; SPTR: FAD dependent oxidoreductase; IMG reference gene:2504586264; PFAM: FAD dependent oxidoreductase YP_004413226.1 COGs: COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain; InterPro IPR001789; KEGG: cst:CLOST_1623 CheY-related protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Chemotaxis protein CheY; IMG reference gene:2504586265; PFAM: Response regulator receiver domain YP_004413227.1 COGs: COG1406 inhibitor of MCP methylation homolog of CheC; InterPro IPR007597; KEGG: cbi:CLJ_B1966 chemotaxis protein CheX; PFAM: CheC-like protein; SPTR: Putative chemotaxis protein CheX; IMG reference gene:2504586266; PFAM: CheC-like family YP_004413228.1 COGs: COG0024 Methionine aminopeptidase; InterPro IPR004027:IPR000994:IPR002467; KEGG: cbe:Cbei_1823 methionine aminopeptidase, type I; PFAM: Peptidase M24, structural domain; SEC-C motif; PRIAM: Methionyl aminopeptidase; SPTR: Methionine aminopeptidase; TIGRFAM: Peptidase M24A, methionine aminopeptidase, subfamily 1; IMG reference gene:2504586267; PFAM: Metallopeptidase family M24; SEC-C motif; TIGRFAM: methionine aminopeptidase, type I YP_004413229.1 COGs: COG0513 Superfamily II DNA and RNA helicase; InterPro IPR011545:IPR001650:IPR014001; KEGG: bbe:BBR47_56570 ATP-dependent RNA helicase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: ATP-dependent RNA helicase DeaD; IMG reference gene:2504586268; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase YP_004413230.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004010:IPR003660:IPR004089; KEGG: hmo:HM1_3092 methyl-accepting chemotaxis signaling protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; Cache; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504586269; PFAM: Cache domain; HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413231.1 COGs: COG2252 Permease; InterPro IPR006043; KEGG: pjd:Pjdr2_0338 xanthine/uracil/vitamin C permease; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Xanthine/uracil permease family protein; IMG reference gene:2504586274 YP_004413232.1 KEGG: afn:Acfer_1229 hypothetical protein; SPTR: Putative lipoprotein; IMG reference gene:2504586275; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase YP_004413233.1 COGs: COG0488 ATPase components of ABC transporter with duplicated ATPase domains; InterPro IPR003593:IPR003439; KEGG: hmo:HM1_2657 abc transporter; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504586276; PFAM: ABC transporter YP_004413234.1 COGs: COG0661 unusual protein kinase; InterPro IPR004147; KEGG: elm:ELI_0454 hypothetical protein; PFAM: ABC-1; SPTR: Protein kinase, ABC1 family; IMG reference gene:2504586277; PFAM: ABC1 family YP_004413235.1 COGs: COG4401 Chorismate mutase; InterPro IPR008243; KEGG: gvi:glr2705 chorismate mutase; PFAM: Chorismate mutase, AroH class; SPTR: Chorismate mutase; TIGRFAM: Chorismate mutase, AroH class; IMG reference gene:2504586278; PFAM: Chorismate mutase type I; TIGRFAM: monofunctional chorismate mutase, gram positive type, clade 1 YP_004413236.1 COGs: COG0251 Putative translation initiation inhibitor yjgF family; InterPro IPR006175:IPR006056; KEGG: pho:PH0854 hypothetical protein; PFAM: Endoribonuclease L-PSP; SPTR: Putative endoribonuclease L-PSP; TIGRFAM: YjgF-like protein; IMG reference gene:2504586279; PFAM: Endoribonuclease L-PSP; TIGRFAM: endoribonuclease L-PSP, putative YP_004413237.1 COGs: COG0227 Ribosomal protein L28; InterPro IPR001383; KEGG: vpr:Vpar_1057 ribosomal protein L28; PFAM: Ribosomal protein L28; SPTR: 50S ribosomal protein L28; TIGRFAM: Ribosomal protein L28; IMG reference gene:2504586280; PFAM: Ribosomal L28 family; TIGRFAM: ribosomal protein L28 YP_004413238.1 COGs: COG0171 NAD synthase; InterPro IPR003010:IPR022310:IPR003694; KEGG: drm:Dred_1460 NAD+ synthetase; PFAM: NAD/GMP synthase; Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; PRIAM: NAD(+) synthase (glutamine-hydrolyzing); SPTR: NAD synthase family protein; TIGRFAM: NAD synthase; IMG reference gene:2504586281; PFAM: NAD synthase; Carbon-nitrogen hydrolase; TIGRFAM: NAD+ synthetase YP_004413239.1 InterPro IPR005357:IPR001387; KEGG: dsy:DSY3841 hypothetical protein; PFAM: Uncharacterised protein family UPF0150; Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, HicB family; IMG reference gene:2504586282; PFAM: Helix-turn-helix; Uncharacterised protein family (UPF0150) YP_004413240.1 InterPro IPR012933; KEGG: afn:Acfer_1288 YcfA family protein; PFAM: Uncharacterised protein family UPF0395; SPTR: Conserved domain protein; IMG reference gene:2504586283; PFAM: YcfA-like protein YP_004413241.1 COGs: COG2606 conserved hypothetical protein; InterPro IPR007214:IPR004369; KEGG: sus:Acid_5432 YbaK/EbsC protein; PFAM: YbaK/aminoacyl-tRNA synthetase-associated domain; SPTR: YbaK/ebsC protein; TIGRFAM: Prolyl-tRNA editing protein, YbaK/EbsC; IMG reference gene:2504586284; PFAM: YbaK / prolyl-tRNA synthetases associated domain; TIGRFAM: ybaK/ebsC protein YP_004413242.1 COGs: COG0498 Threonine synthase; InterPro IPR001926:IPR004450; KEGG: cth:Cthe_1381 threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; TIGRFAM: Threonine synthase; IMG reference gene:2504586285; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004413243.1 COGs: COG1866 Phosphoenolpyruvate carboxykinase (ATP); InterPro IPR001272; KEGG: eel:EUBELI_01169 phosphoenolpyruvate carboxykinase; PFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising; SPTR: Phosphoenolpyruvate carboxykinase [ATP]; TIGRFAM: Phosphoenolpyruvate carboxykinase, ATP-utilising; IMG reference gene:2504586286; PFAM: Phosphoenolpyruvate carboxykinase; TIGRFAM: phosphoenolpyruvate carboxykinase (ATP) YP_004413244.1 COGs: COG1200 RecG-like helicase; InterProIPR004365:IPR011545:IPR001650:IPR004609:IPR 014001; KEGG: tjr:TherJR_2099 ATP-dependent DNA helicase RecG; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: ATP-dependent DNA helicase RecG; TIGRFAM: DNA helicase, ATP-dependent, RecG; IMG reference gene:2504586287; PFAM: Helicase conserved C-terminal domain; OB-fold nucleic acid binding domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecG YP_004413245.1 KEGG: afn:Acfer_0012 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586288 YP_004413246.1 COGs: COG1209 dTDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005907; KEGG: sbc:SbBS512_E1194 glucose-1-phosphate thymidylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate thymidylyltransferase; SPTR: Glucose-1-phosphate thymidylyltransferase; TIGRFAM: Glucose-1-phosphate thymidylyltransferase, long form; IMG reference gene:2504586289; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate thymidylyltransferase, short form YP_004413247.1 COGs: COG1898 dTDP-4-dehydrorhamnose 3 5-epimerase; InterPro IPR000888; KEGG: btb:BMB171_C4864 glucose-1-phosphate thymidylyltransferase; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase-related; PRIAM: dTDP-4-dehydrorhamnose 3,5-epimerase; SPTR: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase-related; IMG reference gene:2504586290; PFAM: dTDP-4-dehydrorhamnose 3,5-epimerase; TIGRFAM: dTDP-4-dehydrorhamnose 3,5-epimerase YP_004413248.1 COGs: COG1088 dTDP-D-glucose 4 6-dehydratase; InterPro IPR001509:IPR005888; KEGG: afn:Acfer_0578 dTDP-glucose 4,6-dehydratase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: dTDP-glucose 4,6-dehydratase; SPTR: dTDP-glucose 4,6-dehydratase; TIGRFAM: dTDP-glucose 4,6-dehydratase; IMG reference gene:2504586291; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: dTDP-glucose 4,6-dehydratase YP_004413249.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: afn:Acfer_1030 transcriptional regulator, LysR family; PFAM: HTH transcriptional regulator, LysR; LysR, substrate-binding; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504586293; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004413250.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; KEGG: afn:Acfer_1029 major facilitator superfamily MFS_1; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator family transporter; IMG reference gene:2504586294; PFAM: Major Facilitator Superfamily YP_004413251.1 COGs: COG0813 Purine-nucleoside phosphorylase; InterPro IPR000845:IPR004402; KEGG: lsa:LSA0797 purine nucleoside phosphorylase; PFAM: Nucleoside phosphorylase domain; PRIAM: Purine-nucleoside phosphorylase; SPTR: Purine nucleoside phosphorylase deoD-type; TIGRFAM: Purine nucleoside phosphorylase; IMG reference gene:2504586300; PFAM: Phosphorylase superfamily; TIGRFAM: purine-nucleoside phosphorylase, family 1 (deoD) YP_004413252.1 COGs: COG1959 transcriptional regulator protein; InterPro IPR000944; KEGG: cpy:Cphy_0009 BadM/Rrf2 family transcriptional regulator; PFAM: Transcription regulator Rrf2; SPTR: Iron-sulfur cluster assembly transcription factor IscR; TIGRFAM: Transcription regulator Rrf2; IMG reference gene:2504586301; PFAM: Transcriptional regulator; TIGRFAM: Rrf2 family protein YP_004413253.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: swo:Swol_0680 trans-hexaprenyltranstransferase; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Heptaprenyl diphosphate synthase component II; IMG reference gene:2504586302; PFAM: Polyprenyl synthetase YP_004413254.1 COGs: COG1826 Sec-independent protein secretion pathway components; InterPro IPR006312:IPR003369; KEGG: tjr:TherJR_1816 twin-arginine translocation protein, TatA/E family subunit; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Sec-independent protein translocase protein tatA/E homolog; TIGRFAM: Twin-arginine translocation protein TatA/E; IMG reference gene:2504586303; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family; twin arginine-targeting protein translocase TatB YP_004413255.1 InterPro IPR006312:IPR003369; KEGG: tth:TTC0018 sec-independent protein translocase protein TatA; PFAM: Bacterial sec-independent translocation protein MttA/Hcf106; SPTR: Sec-independent protein translocase protein TatA; TIGRFAM: Twin-arginine translocation protein TatA/E; IMG reference gene:2504586304; PFAM: mttA/Hcf106 family; TIGRFAM: twin arginine-targeting protein translocase, TatA/E family YP_004413256.1 COGs: COG0805 Sec-independent protein secretion pathway component TatC; InterPro IPR002033:IPR019822; KEGG: vpr:Vpar_1253 sec-independent protein translocase, TatC subunit; PFAM: Sec-independent periplasmic protein translocase; SPTR: Twin arginine-targeting protein translocase TatC; TIGRFAM: Twin arginine-targeting protein translocase, TatC; IMG reference gene:2504586305; PFAM: Sec-independent protein translocase protein (TatC); TIGRFAM: Twin arginine targeting (Tat) protein translocase TatC YP_004413257.1 COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830:IPR022390; KEGG: chy:CHY_1808 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; PFAM: Carboxylyase-related; SPTR: Menaquinone biosynthesis decarboxylase, SCO4490 family; TIGRFAM: Menaquinone biosynthesis decarboxylase, SCO4490; Carboxylyase-related; IMG reference gene:2504586306; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; menaquinone biosynthesis decarboxylase, SCO4490 family YP_004413258.1 COGs: COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferase; InterPro IPR000537:IPR006371; KEGG: mta:Moth_0096 4-hydroxybenzoate octaprenyltransferase; PFAM: UbiA prenyltransferase; SPTR: Putative 4-hydroxybenzoate polyprenyltransferase; TIGRFAM: 4-hydroxybenzoate polyprenyltransferase-related; IMG reference gene:2504586307; PFAM: UbiA prenyltransferase family; TIGRFAM: putative 4-hydroxybenzoate polyprenyltransferase YP_004413259.1 COGs: COG0190 5 10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase; InterPro IPR020631:IPR020630; KEGG: mta:Moth_1516 methenyltetrahydrofolate cyclohydrolase; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; PRIAM: Methylenetetrahydrofolate dehydrogenase (NADP(+)); SPTR: Bifunctional protein folD; IMG reference gene:2504586308; PFAM: Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain YP_004413260.1 COGs: COG2759 Formyltetrahydrofolate synthetase; InterPro IPR000559; KEGG: chy:CHY_2385 formate--tetrahydrofolate ligase; PFAM: Formate-tetrahydrofolate ligase, FTHFS; PRIAM: Formate--tetrahydrofolate ligase; SPTR: Formate--tetrahydrofolate ligase; IMG reference gene:2504586309; PFAM: Formate--tetrahydrofolate ligase YP_004413261.1 InterPro IPR002934; KEGG: ere:EUBREC_1031 hypothetical protein; PFAM: Nucleotidyl transferase domain; SPTR: Putative toxin-antitoxin system, toxin component; IMG reference gene:2504586310; PFAM: Nucleotidyltransferase domain YP_004413262.1 InterPro IPR010235; KEGG: ere:EUBREC_1032 nucleotidyltransferase; PFAM: Nucleotidyltransferase substrate binding protein, HI0074; SPTR: Putative toxin-antitoxin system, antitoxin component; TIGRFAM: Nucleotidyltransferase substrate binding protein, HI0074; IMG reference gene:2504586311; PFAM: Nucleotidyltransferase substrate binding protein like; TIGRFAM: nucleotidyltransferase substrate binding protein, HI0074 family YP_004413263.1 COGs: COG0685 5 10-methylenetetrahydrofolate reductase; InterPro IPR003171; KEGG: hmo:HM1_1450 5,10-methylenetetrahydrofolate reductase; PFAM: Methylenetetrahydrofolate reductase; SPTR: Methylenetetrahydrofolate reductase; IMG reference gene:2504586312; PFAM: Methylenetetrahydrofolate reductase YP_004413264.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333:IPR001433:IPR019480; KEGG: dhd:Dhaf_3502 ferredoxin-NADP(+) reductase subunit alpha; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Oxidoreductase, NAD-binding; IMG reference gene:2504586313; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004413265.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR006004:IPR013027:IPR001327; KEGG: ckr:CKR_0405 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, homotetrameric; TIGRFAM: Glutamate synthase (NADPH), homotetrameric; IMG reference gene:2504586314; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: glutamate synthase (NADPH), homotetrameric YP_004413266.1 COGs: COG0847 DNA polymerase III epsilon subunit and related 3'-5' exonuclease; InterPro IPR013520:IPR006055; KEGG: vpr:Vpar_0406 exonuclease RNase T and DNA polymerase III; PFAM: Exonuclease, RNase T/DNA polymerase III; SMART: Exonuclease; SPTR: Exonuclease; IMG reference gene:2504586315; PFAM: Exonuclease YP_004413267.1 COGs: COG2240 Pyridoxal/pyridoxine/pyridoxamine kinase; InterPro IPR013749; KEGG: dhd:Dhaf_2653 phosphomethylpyrimidine kinase type-1; PFAM: Phosphomethylpyrimidine kinase type-1; SPTR: Putative pyridoxal kinase; IMG reference gene:2504586316; PFAM: Phosphomethylpyrimidine kinase YP_004413268.1 COGs: COG0184 Ribosomal protein S15P/S13E; InterPro IPR000589:IPR005290; KEGG: vpr:Vpar_0768 ribosomal protein S15; PFAM: Ribosomal protein S15; SPTR: 30S ribosomal protein S15; TIGRFAM: Ribosomal protein S15, bacterial-type; IMG reference gene:2504586317; PFAM: Ribosomal protein S15; TIGRFAM: ribosomal protein S15, bacterial/organelle YP_004413269.1 COGs: COG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase); InterProIPR015847:IPR003029:IPR022967:IPR018111:IPR 001247:IPR015848:IPR004087:IPR012162; KEGG: hmo:HM1_2322 polynucleotide phosphorylase/polyadenylase; PFAM: Exoribonuclease, phosphorolytic domain 1; Ribosomal protein S1, RNA-binding domain; Exoribonuclease, phosphorolytic domain 2; K Homology, type 1, subgroup; Polynucleotide phosphorylase, phosphorolytic RNA-binding, bacterial/organelle-type; PRIAM: Polyribonucleotide nucleotidyltransferase; SMART: RNA-binding domain, S1; K Homology; SPTR: Polyribonucleotide nucleotidyltransferase; TIGRFAM: Polyribonucleotide nucleotidyltransferase; IMG reference gene:2504586318; PFAM: KH domain; S1 RNA binding domain; 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; Polyribonucleotide nucleotidyltransferase, RNA binding domain; TIGRFAM: polyribonucleotide nucleotidyltransferase YP_004413270.1 COGs: COG1426 conserved hypothetical protein; InterPro IPR001387; KEGG: mta:Moth_1073 XRE family transcriptional regulator; SMART: Helix-turn-helix type 3; SPTR: Transcriptional regulator, XRE family; IMG reference gene:2504586319 YP_004413271.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR013704:IPR007197:IPR006638; KEGG: aco:Amico_1278 radical SAM domain protein; PFAM: Radical SAM N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: UPF0313 protein SELSPUOL_01650; manually curated; IMG reference gene:2504586320; PFAM: Domain of unknown function (DUF3362); Radical SAM superfamily; Radical SAM N-terminal; TIGRFAM: uncharacterized radical SAM protein YgiQ YP_004413272.1 COGs: COG1327 transcriptional regulator protein consists of a Zn-ribbon and ATP-cone domains; InterPro IPR003796:IPR005144; KEGG: tjr:TherJR_2142 ATP-cone domain protein; PFAM: ATP-cone; SPTR: Transcriptional repressor NrdR; TIGRFAM: Ribonucleotide reductase regulator NrdR-like; IMG reference gene:2504586321; PFAM: ATP cone domain; TIGRFAM: transcriptional regulator NrdR YP_004413273.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR006158:IPR007197:IPR006638; KEGG: vpr:Vpar_1433 radical SAM domain protein; PFAM: Radical SAM; Cobalamin (vitamin B12)-binding; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504586322; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM family uncharacterized protein YP_004413274.1 COGs: COG1496 conserved hypothetical protein; InterPro IPR003730; KEGG: pth:PTH_1832 hypothetical protein; PFAM: Multi-copper polyphenol oxidoreductase, laccase; SPTR: Putative ABC transporter, permease protein; TIGRFAM: Multi-copper polyphenol oxidoreductase, laccase; IMG reference gene:2504586323; PFAM: Multi-copper polyphenol oxidoreductase laccase; TIGRFAM: uncharacterized protein, YfiH family YP_004413275.1 COGs: COG0325 enzyme with a TIM-barrel fold; InterPro IPR001608:IPR011078; KEGG: vpr:Vpar_1431 alanine racemase domain protein; PFAM: Alanine racemase, N-terminal; SPTR: Pyridoxal phosphate enzyme, YggS family; TIGRFAM: pyridoxal phosphate-dependent enzyme, YBL036C type; IMG reference gene:2504586324; PFAM: Alanine racemase, N-terminal domain; TIGRFAM: pyridoxal phosphate enzyme, YggS family YP_004413276.1 COGs: COG1799 conserved hypothetical protein; InterPro IPR007561; KEGG: vpr:Vpar_1430 protein of unknown function DUF552; PFAM: Cell division protein SepF/SepF-related; SPTR: Cell division protein sepF 1; IMG reference gene:2504586325; PFAM: Protein of unknown function (DUF552) YP_004413277.1 COGs: COG0345 Pyrroline-5-carboxylate reductase; InterPro IPR004455:IPR000304; KEGG: adg:Adeg_1017 pyrroline-5-carboxylate reductase; PFAM: NADP oxidoreductase, coenzyme F420-dependent; PRIAM: Pyrroline-5-carboxylate reductase; SPTR: Pyrroline-5-carboxylate reductase; TIGRFAM: Pyrroline-5-carboxylate reductase; IMG reference gene:2504586326; PFAM: NADP oxidoreductase coenzyme F420-dependent; TIGRFAM: pyrroline-5-carboxylate reductase YP_004413278.1 COGs: COG2302 conserved hypothetical protein contains S4-like domain; InterPro IPR002942; KEGG: afn:Acfer_0982 RNA-binding S4 domain protein; PFAM: RNA-binding S4; SMART: RNA-binding S4; SPTR: S4 domain protein; IMG reference gene:2504586327; PFAM: S4 domain YP_004413279.1 COGs: COG0597 Lipoprotein signal peptidase; HAMAP: Peptidase A8, signal peptidase II; InterPro IPR001872; KEGG: nth:Nther_1323 lipoprotein signal peptidase; PFAM: Peptidase A8, signal peptidase II; SPTR: Lipoprotein signal peptidase; TIGRFAM: Peptidase A8, signal peptidase II; IMG reference gene:2504586328; PFAM: Signal peptidase (SPase) II; TIGRFAM: lipoprotein signal peptidase YP_004413280.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR002942:IPR006145; KEGG: afn:Acfer_1508 pseudouridine synthase, RluA family; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; IMG reference gene:2504586329; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase, RluA family YP_004413281.1 COGs: COG2065 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase; InterPro IPR000836; KEGG: pth:PTH_1813 bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Uracil phosphoribosyltransferase; SPTR: Bifunctional protein pyrR; IMG reference gene:2504586330; PFAM: Phosphoribosyl transferase domain YP_004413282.1 KEGG: tde:TDE0948 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586331; PFAM: Putative transposase, YhgA-like YP_004413283.1 InterPro IPR005546:IPR006315; KEGG: ote:Oter_1689 cell wall surface anchor family protein; PFAM: Autotransporter beta-domain; SMART: Autotransporter beta-domain; SPTR: Outer membrane autotransporter barrel domain protein; TIGRFAM: Outer membrane autotransporter barrel; IMG reference gene:2504586332 YP_004413284.1 COGs: COG1098 RNA binding protein (contains ribosomal protein S1 domain); InterPro IPR003029:IPR022967; KEGG: afn:Acfer_1599 RNA binding S1 domain protein; PFAM: Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: RNA-binding protein; IMG reference gene:2504586333; PFAM: S1 RNA binding domain YP_004413285.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; HAMAP: Lysidine-tRNA(Ile) synthetase; InterProIPR011063:IPR015262:IPR012795:IPR012796:IPR 012094; KEGG: mta:Moth_0104 tRNA(Ile)-lysidine synthetase-like; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; Lysidine-tRNA(Ile) synthetase, substrate-binding domain; SMART: Lysidine-tRNA(Ile) synthetase, C-terminal; SPTR: tRNA(Ile)-lysidine synthase; TIGRFAM: Lysidine-tRNA(Ile) synthetase, N-terminal; Lysidine-tRNA(Ile) synthetase, C-terminal; IMG reference gene:2504586334; PFAM: TilS substrate C-terminal domain; PP-loop family; TIGRFAM: tRNA(Ile)-lysidine synthetase, C-terminal domain; tRNA(Ile)-lysidine synthetase, N-terminal domain YP_004413286.1 COGs: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; InterPro IPR005904:IPR000836; KEGG: chy:CHY_1067 hypoxanthine phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Hypoxanthine phosphoribosyltransferase; SPTR: Hypoxanthine phosphoribosyltransferase; TIGRFAM: Hypoxanthine phosphoribosyl transferase; IMG reference gene:2504586335; PFAM: Phosphoribosyl transferase domain; TIGRFAM: hypoxanthine phosphoribosyltransferase YP_004413287.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tpd:Teth39_0404 cobalt transporter ATP-binding subunit; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cobalt import ATP-binding protein CbiO 2; IMG reference gene:2504586336; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit YP_004413288.1 COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: toc:Toce_0150 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cobalt import ATP-binding protein CbiO 1; IMG reference gene:2504586337; PFAM: ABC transporter; Cobalt ATP-binding cassette C terminal; TIGRFAM: cobalt transport protein ATP-binding subunit YP_004413289.1 COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: vpr:Vpar_1463 cobalt transport protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport family protein; IMG reference gene:2504586338; PFAM: Cobalt transport protein YP_004413290.1 COGs: COG0101 Pseudouridylate synthase; InterPro IPR001406:IPR020097; KEGG: tjr:TherJR_0330 tRNA pseudouridine synthase A; PFAM: Pseudouridine synthase I, TruA, alpha/beta domain; PRIAM: tRNA-pseudouridine synthase I; SPTR: tRNA pseudouridine synthase A; TIGRFAM: Pseudouridine synthase I, TruA; IMG reference gene:2504586339; PFAM: tRNA pseudouridine synthase; TIGRFAM: pseudouridylate synthase I YP_004413291.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504586340 YP_004413292.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586341 YP_004413293.1 InterPro IPR007337; KEGG: fsu:Fisuc_2927 addiction module antitoxin, RelB/DinJ family; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504586342; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004413294.1 KEGG: fsu:Fisuc_1833 nucleic acid binding protein; SPTR: Toxin-antitoxin system, toxin component, PIN family; IMG reference gene:2504586343; TIGRFAM: putative toxin-antitoxin system toxin component, PIN family YP_004413295.1 COGs: COG0556 Helicase subunit of the DNA excision repair complex; InterProIPR004807:IPR001650:IPR001943:IPR006935:IPR 014001; KEGG: vpr:Vpar_0708 excinuclease ABC, B subunit; PFAM: Helicase, C-terminal; UvrB/UvrC protein; Restriction endonuclease, type I, R subunit/Type III, Res subunit; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: UvrABC system protein B; TIGRFAM: Excinuclease ABC, B subunit; IMG reference gene:2504586344; PFAM: Helicase conserved C-terminal domain; UvrB/uvrC motif; Type III restriction enzyme, res subunit; Ultra-violet resistance protein B; TIGRFAM: excinuclease ABC, B subunit YP_004413296.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586345 YP_004413297.1 InterPro IPR006674; KEGG: dae:Dtox_1720 HD domain-containing protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Metal-dependent phosphohydrolase; IMG reference gene:2504586346; PFAM: HD domain YP_004413298.1 COGs: COG0008 Glutamyl- and glutaminyl-tRNA synthetase; HAMAP: Glutaminyl-tRNA synthetase, bacterial; InterPro IPR020058:IPR020059:IPR004514:IPR022861; KEGG: slp:Slip_2326 glutaminyl-tRNA synthetase; PFAM: Glutamyl/glutaminyl-tRNA synthetase, class Ic, catalytic domain; Glutamyl/glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain; PRIAM: Glutamine--tRNA ligase; SPTR: Glutaminyl-tRNA synthetase; TIGRFAM: Glutaminyl-tRNA synthetase, class Ic; IMG reference gene:2504586347; PFAM: tRNA synthetases class I (E and Q), catalytic domain; tRNA synthetases class I (E and Q), anti-codon binding domain; TIGRFAM: glutaminyl-tRNA synthetase YP_004413299.1 KEGG: drm:Dred_1414 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586348 YP_004413300.1 COGs: COG1055 Na+/H+ antiporter NhaD and related arsenite permease; InterPro IPR004680; KEGG: bbe:BBR47_24210 hypothetical protein; PFAM: Divalent ion symporter; SPTR: Arsenic transporter family protein; IMG reference gene:2504586349; PFAM: Citrate transporter YP_004413301.1 COGs: COG0495 Leucyl-tRNA synthetase; InterPro IPR002300:IPR013155:IPR002302; KEGG: afn:Acfer_0634 leucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Leucine--tRNA ligase; SPTR: Leucyl-tRNA synthetase; TIGRFAM: Leucyl-tRNA synthetase, class Ia, bacterial/mitochondrial; IMG reference gene:2504586350; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family YP_004413302.1 COGs: COG1197 Transcription-repair coupling factor (superfamily II helicase); InterProIPR004576:IPR011545:IPR003711:IPR001650:IPR 005118:IPR014001; KEGG: vpr:Vpar_1362 transcription-repair coupling factor; PFAM: Transcription factor CarD; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Transcription-repair-coupling factor domain; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Transcription-repair coupling factor; TIGRFAM: Transcription-repair coupling factor; IMG reference gene:2504586351; PFAM: Helicase conserved C-terminal domain; TRCF domain; CarD-like/TRCF domain; DEAD/DEAH box helicase; TIGRFAM: transcription-repair coupling factor (mfd) YP_004413303.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR000878; KEGG: cac:CA_C3212 hypothetical protein; PFAM: Tetrapyrrole methylase; SPTR: Tetrapyrrole methylase family protein; IMG reference gene:2504586352; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases YP_004413304.1 COGs: COG0776 Bacterial nucleoid DNA-binding protein; InterPro IPR000119; KEGG: mta:Moth_0085 nucleoid protein Hbs; PFAM: Histone-like bacterial DNA-binding protein; SMART: Histone-like bacterial DNA-binding protein; SPTR: DNA-binding protein HU; IMG reference gene:2504586353; PFAM: Bacterial DNA-binding protein YP_004413305.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198; KEGG: vpr:Vpar_0426 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SPTR: Cyclopentanol dehydrogenase; IMG reference gene:2504586354; PFAM: short chain dehydrogenase YP_004413306.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR009695:IPR007235; KEGG: vpr:Vpar_1358 monogalactosyldiacylglycerol synthase; PFAM: Monogalactosyldiacylglycerol synthase; Glycosyl transferase, family 28, C-terminal; SPTR: Putative UDP-glucuronosyltransferase; IMG reference gene:2504586355; PFAM: Glycosyltransferase family 28 C-terminal domain; Monogalactosyldiacylglycerol (MGDG) synthase YP_004413307.1 SPTR: Conserved domain protein; IMG reference gene:2504586356 YP_004413308.1 InterPro IPR007060; KEGG: cac:CA_C3207 hypothetical protein; PFAM: Septum formation initiator; SPTR: Putative cell division protein FtsL; IMG reference gene:2504586357; PFAM: Septum formation initiator YP_004413309.1 InterPro IPR005357; KEGG: bbp:BBPR_0901 phage protein; PFAM: Uncharacterised protein family UPF0150; SPTR: Toxin-antitoxin system, antitoxin component, HicB family; IMG reference gene:2504586358; PFAM: Uncharacterised protein family (UPF0150) YP_004413310.1 InterPro IPR012933; KEGG: bbp:BBPR_0900 YcfA family protein; PFAM: Uncharacterised protein family UPF0395; SPTR: Toxin-antitoxin system, toxin component, HicA family; IMG reference gene:2504586359; PFAM: YcfA-like protein YP_004413311.1 IMG reference gene:2504586360 YP_004413312.1 COGs: COG1161 GTPase; InterPro IPR002917:IPR019991; KEGG: tjr:TherJR_2041 ribosome biogenesis GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; SPTR: Ribosome biogenesis GTP-binding protein YlqF; TIGRFAM: GTP-binding protein, ribosome biogenesis, YlqF; IMG reference gene:2504586361; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YlqF YP_004413313.1 COGs: COG0164 Ribonuclease HII; InterPro IPR001352; KEGG: bcb:BCB4264_A3935 ribonuclease HII; PFAM: Ribonuclease HII/HIII; PRIAM: Ribonuclease H; SPTR: Ribonuclease HII; IMG reference gene:2504586362; PFAM: Ribonuclease HII YP_004413314.1 KEGG: rdn:HMPREF0733_10170 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586363 YP_004413315.1 COGs: COG2257 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB; InterPro IPR006135; KEGG: bbe:BBR47_36070 hypothetical protein; PFAM: Type III secretion exporter; SPTR: Flagellar biosynthesis protein; IMG reference gene:2504586364; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: flhB C-terminus-related protein YP_004413316.1 COGs: COG0792 endonuclease distantly related to Holliday junction resolvase; InterPro IPR003509; KEGG: afn:Acfer_0476 protein of unknown function UPF0102; PFAM: Uncharacterised protein family UPF0102; SPTR: UPF0102 protein SELSPUOL_01728; TIGRFAM: Uncharacterised protein family UPF0102; IMG reference gene:2504586365; PFAM: Uncharacterised protein family UPF0102; TIGRFAM: TIGR00252 family protein YP_004413317.1 COGs: COG2243 Precorrin-2 methylase; InterPro IPR006364:IPR000878; KEGG: vpr:Vpar_1130 precorrin-2 C20-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-2 C(20)-methyltransferase; SPTR: Precorrin-2 C(20)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobI/CbiL, precorrin-2 C20-methyltransferase, core; IMG reference gene:2504586366; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-2 C20-methyltransferase YP_004413318.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dsy:DSY3874 hypothetical protein; PFAM: Periplasmic binding protein; SPTR: Putative lipoprotein; IMG reference gene:2504586367; PFAM: Periplasmic binding protein YP_004413319.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: vpr:Vpar_1138 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: Ferrichrome transport system permease protein FhuB; IMG reference gene:2504586368; PFAM: FecCD transport family YP_004413320.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: bcy:Bcer98_2406 ABC transporter-related protein; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ferrichrome transport ATP-binding protein FhuC; IMG reference gene:2504586369; PFAM: ABC transporter YP_004413321.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: chy:CHY_0059 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504586370; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004413322.1 COGs: COG1196 Chromosome segregation ATPase; InterPro IPR003395:IPR010935:IPR011890; KEGG: afn:Acfer_1506 chromosome segregation protein SMC; PFAM: RecF/RecN/SMC; SMCs flexible hinge; SMART: SMCs flexible hinge; SPTR: Putative cell division protein Smc; TIGRFAM: Chromosome segregation protein SMC; IMG reference gene:2504586371; PFAM: RecF/RecN/SMC N terminal domain; SMC proteins Flexible Hinge Domain; TIGRFAM: chromosome segregation protein SMC, common bacterial type YP_004413323.1 COGs: COG0552 Signal recognition particle GTPase; InterPro IPR013822:IPR003593:IPR004390:IPR000897; KEGG: vpr:Vpar_0706 signal recognition particle-docking protein FtsY; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; SMART: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; ATPase, AAA+ type, core; SPTR: Signal recognition particle-docking protein FtsY; TIGRFAM: Cell division transporter substrate-binding protein FtsY; IMG reference gene:2504586372; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; TIGRFAM: signal recognition particle-docking protein FtsY YP_004413324.1 COGs: COG1217 membrane GTPase involved in stress response; InterProIPR005225:IPR006298:IPR000795:IPR004161:IPR 000640; KEGG: vpr:Vpar_1324 GTP-binding protein TypA; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, C-terminal; SPTR: GTP-binding protein TypA/BipA; TIGRFAM: GTP-binding protein TypA; Small GTP-binding protein; IMG reference gene:2504586373; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; TIGRFAM: GTP-binding protein TypA/BipA; small GTP-binding protein domain YP_004413325.1 COGs: COG1799 conserved hypothetical protein; HAMAP: Cell division protein SepF; InterPro IPR007561:IPR023052; KEGG: pjd:Pjdr2_3877 protein of unknown function DUF552; PFAM: Cell division protein SepF/SepF-related; SPTR: Cell division protein sepF 2; IMG reference gene:2504586374; PFAM: Protein of unknown function (DUF552) YP_004413326.1 COGs: COG2195 Di- and tripeptidase; InterPro IPR001160:IPR002933; KEGG: aba:Acid345_1504 peptidase M20C, Xaa-His dipeptidase; PFAM: Peptidase M20; PRIAM: Xaa-His dipeptidase; SPTR: Aminoacyl-histidine dipeptidase; TIGRFAM: Peptidase M20C, Xaa-His dipeptidase; IMG reference gene:2504586375; PFAM: Peptidase family M20/M25/M40; TIGRFAM: aminoacyl-histidine dipeptidase YP_004413327.1 InterPro IPR002656; KEGG: vpr:Vpar_0420 hypothetical protein; PFAM: Acyltransferase 3; SPTR: Putative membrane protein; IMG reference gene:2504586376; PFAM: Acyltransferase family YP_004413328.1 COGs: COG0796 Glutamate racemase; HAMAP: Glutamate racemase; InterPro IPR015942:IPR004391; KEGG: cpf:CPF_2893 glutamate racemase; PFAM: Asp/Glu/hydantoin racemase; PRIAM: Glutamate racemase; SPTR: Glutamate racemase; TIGRFAM: Glutamate racemase; IMG reference gene:2504586377; PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: glutamate racemase YP_004413329.1 COGs: COG5496 thioesterase; InterPro IPR006683; KEGG: afn:Acfer_0121 hypothetical protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family protein; IMG reference gene:2504586378; PFAM: Thioesterase superfamily YP_004413330.1 COGs: COG1296 branched-chain amino acid permease (azaleucine resistance); InterPro IPR011606; KEGG: ols:Olsu_1157 AzlC family protein; PFAM: Branched-chain amino acid transport, permease; SPTR: Putative branched-chain amino acid transporter; IMG reference gene:2504586379; PFAM: AzlC protein YP_004413331.1 InterPro IPR008407; KEGG: ols:Olsu_1156 branched-chain amino acid transport; PFAM: Branched-chain amino acid transport, AzlD; SPTR: Branched-chain amino acid transport protein; IMG reference gene:2504586380; PFAM: Branched-chain amino acid transport protein (AzlD) YP_004413332.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: ctc:CTC01487 methyl-accepting chemotaxis-like protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504586381; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413333.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: cbl:CLK_2081 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504586382; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413334.1 COGs: COG1160 GTPase; InterPro IPR002917:IPR005225; KEGG: csh:Closa_2395 small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein; TIGRFAM: Small GTP-binding protein; IMG reference gene:2504586383; PFAM: GTPase of unknown function; TIGRFAM: hydrogenase maturation GTPase HydF; small GTP-binding protein domain YP_004413335.1 COGs: COG0068 Hydrogenase maturation factor; InterPro IPR006070:IPR001792:IPR004421:IPR011125; KEGG: clj:CLJU_c23090 putative hydrogenase maturation protein HypF; PFAM: Sua5/YciO/YrdC, N-terminal; Acylphosphatase-like; Zinc finger, HypF-type; SPTR: [NiFe] hydrogenase maturation protein HypF; TIGRFAM: Carbamoyltransferase, HypF-type; IMG reference gene:2504586384; PFAM: HypF finger; yrdC domain; Acylphosphatase; TIGRFAM: [NiFe] hydrogenase maturation protein HypF YP_004413336.1 COGs: COG0174 Glutamine synthetase; InterPro IPR008146; KEGG: vpr:Vpar_0890 glutamine synthetase catalytic region; PFAM: Glutamine synthetase, catalytic domain; SPTR: Glutamate--ammonia ligase; IMG reference gene:2504586385; PFAM: Glutamine synthetase, catalytic domain YP_004413337.1 KEGG: mem:Memar_1738 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586386 YP_004413338.1 COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR006098; KEGG: vpr:Vpar_1763 methylmalonyl-CoA mutase; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase beta subunit; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; IMG reference gene:2504586387; PFAM: Methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase, heterodimeric type, beta chain YP_004413339.1 COGs: COG1884 Methylmalonyl-CoA mutase N-terminal domain/subunit; InterPro IPR006099:IPR006159:IPR006158:IPR006098; KEGG: vpr:Vpar_1762 methylmalonyl-CoA mutase, large subunit; PFAM: Methylmalonyl-CoA mutase, alpha/beta chain, catalytic; Cobalamin (vitamin B12)-binding; PRIAM: Methylmalonyl-CoA mutase; SPTR: Methylmalonyl-CoA mutase, large subunit; TIGRFAM: Methylmalonyl-CoA mutase, alpha chain, catalytic; Methylmalonyl-CoA mutase, C-terminal; IMG reference gene:2504586388; PFAM: Methylmalonyl-CoA mutase; B12 binding domain; TIGRFAM: methylmalonyl-CoA mutase N-terminal domain; methylmalonyl-CoA mutase C-terminal domain YP_004413340.1 COGs: COG1703 Putative periplasmic protein kinase ArgK and related GTPase of G3E family; InterPro IPR005129; KEGG: vpr:Vpar_1761 LAO/AO transport system ATPase; PFAM: ArgK protein; SPTR: LAO/AO transport system ATPase; TIGRFAM: ArgK protein; IMG reference gene:2504586389; PFAM: ArgK protein; TIGRFAM: LAO/AO transport system ATPase YP_004413341.1 COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569; KEGG: pgn:PGN_0140 peptide methionine sulfoxide reductase; PFAM: Peptide methionine sulphoxide reductase MsrA; SPTR: Peptide-methionine (S)-S-oxide reductase; IMG reference gene:2504586390; PFAM: Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase YP_004413342.1 COGs: COG1903 Cobalamin biosynthesis protein CbiD; InterPro IPR002748; KEGG: vpr:Vpar_1146 cobalamin biosynthesis protein CbiD; PFAM: Cobalamin (vitamin B12) biosynthesis CbiD; SPTR: Putative cobalt-precorrin-6A synthase [deacetylating]; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiD; IMG reference gene:2504586391; PFAM: CbiD; TIGRFAM: cobalamin biosynthesis protein CbiD YP_004413343.1 COGs: COG2241 Precorrin-6B methylase 1; InterPro IPR000878:IPR012818; KEGG: vpr:Vpar_1145 precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; PFAM: Tetrapyrrole methylase; SPTR: Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; manually curated; IMG reference gene:2504586392; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit YP_004413344.1 COGs: COG2242 Precorrin-6B methylase 2; InterPro IPR003682:IPR014008; KEGG: has:Halsa_2200 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: rRNA small subunit methyltransferase G; SPTR: Precorrin-6y c5,15-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiT, precorrin-6Y methyltransferase-core; IMG reference gene:2504586393; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit YP_004413345.1 COGs: COG2875 Precorrin-4 methylase; InterPro IPR006362:IPR000878; KEGG: vpr:Vpar_1143 precorrin-4 C11-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-4 C(11)-methyltransferase; SPTR: Precorrin-4 C(11)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase, core; IMG reference gene:2504586394; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-4 C11-methyltransferase YP_004413346.1 COGs: COG2073 Cobalamin biosynthesis protein CbiG; InterPro IPR021744:IPR002750; KEGG: aar:Acear_0836 cobalamin (vitamin B12) biosynthesis CbiG protein; PFAM: Cobalamin synthesis G N-terminal; Cobalamin (vitamin B12) biosynthesis CbiG, core; SPTR: CbiG protein; IMG reference gene:2504586395; PFAM: Cobalamin synthesis G C-terminus; Cobalamin synthesis G N-terminal YP_004413347.1 COGs: COG1010 Precorrin-3B methylase; InterPro IPR006363:IPR000878; KEGG: vpr:Vpar_1141 precorrin-3B C17-methyltransferase; PFAM: Tetrapyrrole methylase; PRIAM: Precorrin-3B C(17)-methyltransferase; SPTR: Precorrin-3B C(17)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobJ/CibH, precorrin-3B C17-methyltransferase, core; IMG reference gene:2504586396; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: precorrin-3B C17-methyltransferase YP_004413348.1 COGs: COG2099 Precorrin-6x reductase; InterPro IPR003723; KEGG: vpr:Vpar_1140 precorrin-6x reductase; PFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; SPTR: Precorrin-6x reductase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CobK/CbiJ, precorrin-6x reductase; IMG reference gene:2504586397; PFAM: Precorrin-6x reductase CbiJ/CobK; TIGRFAM: precorrin-6x reductase YP_004413349.1 COGs: COG2082 Precorrin isomerase; InterPro IPR003722; KEGG: vpr:Vpar_1139 precorrin-8X methylmutase CbiC/CobH; PFAM: Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase, core; PRIAM: Precorrin-8X methylmutase; SPTR: Precorrin-8X methylmutase; IMG reference gene:2504586398; PFAM: Precorrin-8X methylmutase YP_004413350.1 COGs: COG1797 Cobyrinic acid a c-diamide synthase; InterPro IPR002586:IPR004484:IPR011698; KEGG: vpr:Vpar_1129 cobyrinic acid a,c-diamide synthase; PFAM: CobB/CobQ-like glutamine amidotransferase; Cobyrinic acid a,c-diamide synthase; SPTR: Cobyrinic Acid a,c-diamide synthase; TIGRFAM: Cobyrinic acid a,c-diamide synthase CbiA; IMG reference gene:2504586399; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyrinic acid a,c-diamide synthase YP_004413351.1 COGs: COG2087 Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase; InterPro IPR003203; KEGG: rrs:RoseRS_0575 adenosylcobinamide-phosphate guanylyltransferase; PFAM: Cobinamide kinase/cobinamide phosphate guanyltransferase; PRIAM: Adenosylcobinamide-phosphate guanylyltransferase; SPTR: Adenosylcobalamin biosynthesis protein CobU; IMG reference gene:2504586400; PFAM: Cobinamide kinase / cobinamide phosphate guanyltransferase YP_004413352.1 COGs: COG1492 Cobyric acid synthase; HAMAP: Cobyric acid synthase CobQ; InterPro IPR004459:IPR002586:IPR011698; KEGG: vpr:Vpar_0906 cobyric acid synthase CobQ; PFAM: CobB/CobQ-like glutamine amidotransferase; Cobyrinic acid a,c-diamide synthase; SPTR: Cobyric acid synthase; TIGRFAM: Cobyric acid synthase CobQ; IMG reference gene:2504586401; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; CobB/CobQ-like glutamine amidotransferase domain; TIGRFAM: cobyric acid synthase CobQ YP_004413353.1 COGs: COG1270 Cobalamin biosynthesis protein CobD/CbiB; InterPro IPR004485; KEGG: vpr:Vpar_0907 cobalamin biosynthesis protein CobD; PFAM: Cobalamin biosynthesis CobD/CbiB; SPTR: Cobalamin biosynthesis protein CobD; TIGRFAM: Cobalamin biosynthesis CobD/CbiB; IMG reference gene:2504586402; PFAM: CobD/Cbib protein; TIGRFAM: cobalamin biosynthesis protein CobD YP_004413354.1 COGs: COG0368 Cobalamin-5-phosphate synthase; HAMAP: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; InterPro IPR003805; KEGG: vpr:Vpar_0908 cobalamin 5'-phosphate synthase; PFAM: Cobalamin (vitamin B12) biosynthesis CobS, cobalamin-5-phosphate synthase; SPTR: Cobalamin synthase; IMG reference gene:2504586403; PFAM: Cobalamin-5-phosphate synthase; TIGRFAM: cobalamin 5'-phosphate synthase/cobalamin synthase YP_004413355.1 COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005860:IPR004839; KEGG: tjr:TherJR_1312 L-threonine-O-3-phosphate decarboxylase; PFAM: Aminotransferase, class I/classII; SPTR: Threonine-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; manually curated; IMG reference gene:2504586404; PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase YP_004413356.1 COGs: COG0406 Fructose-2 6-bisphosphatase; InterPro IPR013078; KEGG: drm:Dred_1908 phosphoglycerate mutase; PFAM: Histidine phosphatase superfamily, clade-1; SMART: Histidine phosphatase superfamily, clade-1; SPTR: Phosphoglycerate mutase family protein; IMG reference gene:2504586405; PFAM: Phosphoglycerate mutase family; TIGRFAM: alpha-ribazole phosphatase YP_004413357.1 COGs: COG1323 nucleotidyltransferase; InterPro IPR008513; KEGG: aoe:Clos_1446 hypothetical protein; PFAM: Uncharacterised protein family UPF0348; SPTR: UPF0348 protein SELSPUOL_00285; IMG reference gene:2504586411; PFAM: Protein of unknown function (DUF795) YP_004413358.1 COGs: COG0482 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain; HAMAP: tRNA-specific 2-thiouridylase; InterPro IPR004506; KEGG: tte:TTE1243 tRNA-specific 2-thiouridylase MnmA; PFAM: tRNA-specific 2-thiouridylase; SPTR: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; TIGRFAM: tRNA-specific 2-thiouridylase; IMG reference gene:2504586412; PFAM: tRNA methyl transferase; TIGRFAM: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase YP_004413359.1 KEGG: afn:Acfer_1323 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586413 YP_004413360.1 COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: afn:Acfer_0374 BioY protein; PFAM: BioY protein; SPTR: BioY family protein; IMG reference gene:2504586414; PFAM: BioY family YP_004413361.1 InterPro IPR021139; KEGG: fjo:Fjoh_2410 hypothetical protein; PFAM: Domain of unknown function DUF88; SPTR: Putative uncharacterized protein; IMG reference gene:2504586415; PFAM: Protein of unknown function DUF88 YP_004413362.1 KEGG: ere:EUBREC_0207 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586416 YP_004413363.1 KEGG: ngr:NAEGRDRAFT_52736 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586417 YP_004413364.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR015168:IPR001638; KEGG: toc:Toce_1346 extracellular solute-binding protein family 3; SMART: Extracellular solute-binding protein, family 3; SPTR: NLPA lipoprotein; IMG reference gene:2504586418; PFAM: NMT1/THI5 like YP_004413365.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: toc:Toce_1345 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Taurine ABC transporter, ATP-binding protein; IMG reference gene:2504586419; PFAM: ABC transporter YP_004413366.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: toc:Toce_1344 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: ABC transporter, permease protein; IMG reference gene:2504586420; PFAM: Binding-protein-dependent transport system inner membrane component YP_004413367.1 InterPro IPR019657; KEGG: mta:Moth_0071 hypothetical protein; PFAM: Late competence development protein ComFB; SPTR: Putative ComF operon protein; IMG reference gene:2504586421; PFAM: Late competence development protein ComFB YP_004413368.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR002550:IPR000644:IPR005170; KEGG: mru:mru_1952 CBS domain-containing protein; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain protein; IMG reference gene:2504586422; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004413369.1 COGs: COG2720 Uncharacterized vancomycin resistance protein; InterPro IPR007391; KEGG: cdf:CD2149 hypothetical protein; PFAM: Vancomycin resistance VanW; SPTR: VanW protein; IMG reference gene:2504586423; PFAM: Putative peptidoglycan binding domain; VanW like protein YP_004413370.1 COGs: COG0163 3-polyprenyl-4-hydroxybenzoate decarboxylase; InterPro IPR004507:IPR003382; KEGG: cro:ROD_30701 putative 4-hydroxybenzoate decarboxylase subunit B; PFAM: Flavoprotein; SPTR: Phenylacrylic acid decarboxylase, 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: Phenylacrylic acid decarboxylase; IMG reference gene:2504586424; PFAM: Flavoprotein; TIGRFAM: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases YP_004413371.1 COGs: COG1236 exonuclease of the beta-lactamase fold involved in RNA processing; InterPro IPR001279:IPR011108; KEGG: afn:Acfer_0551 RNA-metabolising metallo-beta-lactamase; PFAM: Beta-lactamase-like; RNA-metabolising metallo-beta-lactamase; SMART: Beta-lactamase-like; SPTR: Metallo-beta-lactamase family protein; IMG reference gene:2504586425; PFAM: Metallo-beta-lactamase superfamily; RNA-metabolising metallo-beta-lactamase; Beta-Casp domain YP_004413372.1 COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; HAMAP: Aspartate carbamoyltransferase, eukaryotic; InterPro IPR002082:IPR006132:IPR006131; KEGG: vpr:Vpar_0563 aspartate carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2504586426; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase YP_004413373.1 COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; InterPro IPR004722:IPR006680; KEGG: afn:Acfer_1317 dihydroorotase, multifunctional complex type; PFAM: Amidohydrolase 1; PRIAM: Dihydroorotase; SPTR: Dihydroorotase; TIGRFAM: Dihydroorotase; IMG reference gene:2504586427; PFAM: Amidohydrolase family; TIGRFAM: dihydroorotase, multifunctional complex type YP_004413374.1 COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR002474:IPR000991:IPR006274; KEGG: vpr:Vpar_0565 carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase, small subunit, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; IMG reference gene:2504586428; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit YP_004413375.1 COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR011607:IPR005480:IPR005479:IPR 005481; KEGG: afn:Acfer_1315 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; Carbamoyl-phosphate synthase, large subunit, N-terminal; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate synthase, large subunit; IMG reference gene:2504586429; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit YP_004413376.1 COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR014732:IPR001754; KEGG: vpr:Vpar_0405 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase; IMG reference gene:2504586430; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 1 YP_004413377.1 COGs: COG0461 Orotate phosphoribosyltransferase; InterPro IPR000836:IPR006273; KEGG: afn:Acfer_1311 orotate phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; PRIAM: Orotate phosphoribosyltransferase; SPTR: Orotate phosphoribosyltransferase; TIGRFAM: Orotate phosphoribosyltransferase, Thermus type; IMG reference gene:2504586431; PFAM: Phosphoribosyl transferase domain; TIGRFAM: orotate phosphoribosyltransferase, Thermus family; orotate phosphoribosyltransferase YP_004413378.1 KEGG: afn:Acfer_0724 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586432 YP_004413379.1 COGs: COG4100 Cystathionine beta-lyase family protein involved in aluminum resistance; InterPro IPR009651; KEGG: dae:Dtox_2133 aluminium resistance family protein; PFAM: Aluminium resistance; SPTR: Aluminum resistance protein; IMG reference gene:2504586433; PFAM: Aluminium resistance protein YP_004413380.1 COGs: COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidase); HAMAP: Peptidase S24, LexA repressor; InterPro IPR006200:IPR006199:IPR019759; KEGG: afl:Aflv_1506 SOS-response transcriptional repressor (RecA-mediated autopeptidase); PFAM: LexA, DNA-binding domain; Peptidase S24/S26A/S26B, conserved region; SPTR: Repressor LexA; TIGRFAM: Peptidase S24, LexA repressor; IMG reference gene:2504586434; PFAM: LexA DNA binding domain; Peptidase S24-like; TIGRFAM: SOS regulatory protein LexA YP_004413381.1 InterPro IPR007560; KEGG: ttm:Tthe_0929 hypothetical protein; PFAM: Restriction endonuclease, type IV-like, Mrr; SPTR: Putative uncharacterized protein; IMG reference gene:2504586435; PFAM: Restriction endonuclease YP_004413382.1 InterPro IPR002934; KEGG: swo:Swol_1102 hypothetical protein; PFAM: Nucleotidyl transferase domain; SPTR: Nucleotidyltransferase domain protein; IMG reference gene:2504586438; PFAM: Nucleotidyltransferase domain YP_004413383.1 COGs: COG2361 conserved hypothetical protein; InterPro IPR008201; KEGG: tte:TTE0752 hypothetical protein; PFAM: Protein of unknown function DUF86; SPTR: Putative toxin-antitoxin system, antitoxin component; IMG reference gene:2504586439; PFAM: Protein of unknown function DUF86 YP_004413384.1 COGs: COG2831 Hemolysin activation/secretion protein; InterPro IPR013686:IPR005565; KEGG: afn:Acfer_1778 polypeptide-transport-associated domain protein ShlB-type; PFAM: Polypeptide-transport-associated, ShlB-type; Haemolysin activator HlyB; SPTR: Outer membrane hemolysin activator protein; IMG reference gene:2504586440; PFAM: Haemolysin secretion/activation protein ShlB/FhaC/HecB; POTRA domain, ShlB-type YP_004413385.1 KEGG: afn:Acfer_1769 hypothetical protein; SPTR: Protein A15; IMG reference gene:2504586441 YP_004413386.1 KEGG: afn:Acfer_1770 hypothetical protein; SPTR: Filamentous hemagglutinin family protein; IMG reference gene:2504586442 YP_004413387.1 SPTR: Putative transcriptional regulator; manually curated; IMG reference gene:2504586443 YP_004413388.1 KEGG: afn:Acfer_1776 adhesin HecA family; SPTR: Putative hemagglutinin-related protein; IMG reference gene:2504586444 YP_004413389.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: cce:Ccel_3266 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504586445; PFAM: Transposase IS200 like YP_004413390.1 COGs: COG2378 transcriptional regulator protein; KEGG: bpb:bpr_IV145 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586447 YP_004413391.1 KEGG: dda:Dd703_0812 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586448 YP_004413392.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR012441:IPR005502; KEGG: drt:Dret_0672 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; Protein of unknown function DUF1643; SPTR: ADP-ribosylglycohydrolase family protein; IMG reference gene:2504586449; PFAM: ADP-ribosylglycohydrolase; Protein of unknown function (DUF1643) YP_004413393.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586450 YP_004413394.1 InterPro IPR001584; KEGG: bbe:BBR47_48770 transposase orfB for insertion sequence element IS3 family; PFAM: Integrase, catalytic core; SPTR: Putative transposase InsK; IMG reference gene:2504586451; PFAM: Integrase core domain YP_004413395.1 KEGG: avn:Avin_36430 hypothetical protein; SPTR: 3-deoxy-7-phosphoheptulonate synthase; IMG reference gene:2504586452 YP_004413396.1 InterPro IPR002514; KEGG: dsy:DSY0820 hypothetical protein; PFAM: Transposase IS3/IS911family; SPTR: Transposase; IMG reference gene:2504586454; PFAM: Transposase YP_004413397.1 COGs: COG2801 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: dsy:DSY0819 hypothetical protein; PFAM: Integrase, catalytic core; SPTR: Putative ISMca2, transposase, OrfB; IMG reference gene:2504586455; PFAM: Integrase core domain YP_004413398.1 KEGG: ere:EUBREC_0928 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586456; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413399.1 KEGG: ere:EUBREC_1158 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586457 YP_004413400.1 InterPro IPR001584; KEGG: bbe:BBR47_48770 transposase orfB for insertion sequence element IS3 family; PFAM: Integrase, catalytic core; SPTR: Putative transposase InsK; IMG reference gene:2504586458; PFAM: Integrase core domain YP_004413401.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586459 YP_004413402.1 KEGG: csh:Closa_3687 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586460 YP_004413403.1 KEGG: rdn:HMPREF0733_11805 Mg chelatase-like protein; SPTR: Mg chelatase-like protein; IMG reference gene:2504586461 YP_004413404.1 COGs: COG0606 ATPase with chaperone activity; InterPro IPR004482:IPR000523:IPR003593; KEGG: afn:Acfer_0477 Mg chelatase, subunit ChlI; PFAM: Magnesium chelatase, ChlI subunit; SMART: ATPase, AAA+ type, core; SPTR: Mg chelatase-like protein; TIGRFAM: Mg chelatase-related protein; IMG reference gene:2504586462; PFAM: Magnesium chelatase, subunit ChlI; TIGRFAM: Mg chelatase-related protein YP_004413405.1 InterPro IPR007076; KEGG: mru:mru_0517 TfoX N-terminal domain-containing protein; PFAM: TfoX, N-terminal; SPTR: TfoX domain protein; IMG reference gene:2504586463; PFAM: TfoX N-terminal domain YP_004413406.1 COGs: COG1392 Phosphate transport regulator (distant homolog of PhoU); InterPro IPR018445; KEGG: hmo:HM1_2747 conserved hypothetical protein, possible phosphate transport regulator; PFAM: Putitive phosphate transport regulator; SPTR: Phosphate transport regulator; IMG reference gene:2504586464; PFAM: Protein of unknown function DUF47 YP_004413407.1 COGs: COG0306 Phosphate/sulphate permease; InterPro IPR001204; KEGG: vpr:Vpar_1353 phosphate transporter; PFAM: Phosphate transporter; SPTR: Phosphate transporter; IMG reference gene:2504586465; PFAM: Phosphate transporter family YP_004413408.1 COGs: COG0572 Uridine kinase; InterPro IPR006083; KEGG: tte:TTE1778 uridine kinase; PFAM: Phosphoribulokinase/uridine kinase; SPTR: Phosphoribulokinase family protein; IMG reference gene:2504586466; PFAM: Phosphoribulokinase / Uridine kinase family YP_004413409.1 COGs: COG5016 Pyruvate/oxaloacetate carboxyltransferase; InterPro IPR000891:IPR003379; KEGG: tit:Thit_1131 conserved carboxylase region; PFAM: Carboxylase, conserved domain; Pyruvate carboxyltransferase; PRIAM: Pyruvate carboxylase; SPTR: Oxaloacetate decarboxylase alpha subunit; IMG reference gene:2504586467; PFAM: HMGL-like; Conserved carboxylase domain YP_004413410.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR005784:IPR001544; KEGG: lsp:Bsph_4219 D-alanine aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: D-amino-acid transaminase; SPTR: D-amino-acid transaminase; TIGRFAM: D-amino acid aminotransferase; IMG reference gene:2504586468; PFAM: Aminotransferase class IV; TIGRFAM: D-amino acid aminotransferase YP_004413411.1 COGs: COG3830 ACT domain-containing protein; InterPro IPR002912; KEGG: chd:Calhy_0638 act domain-containing protein; PFAM: Amino acid-binding ACT; SPTR: UPF0237 protein SELSPUOL_00227; IMG reference gene:2504586469; PFAM: ACT domain YP_004413412.1 COGs: COG2848 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0210; InterPro IPR007841; KEGG: afn:Acfer_1482 protein of unknown function DUF711; PFAM: Uncharacterised protein family UPF0210; SPTR: UPF0210 protein SELSPUOL_00226; IMG reference gene:2504586470; PFAM: Uncharacterized ACR (DUF711) YP_004413413.1 COGs: COG0177 EndoIII-related endonuclease; InterProIPR003583:IPR003265:IPR000445:IPR003651:IPR 005759; KEGG: vpr:Vpar_1103 endonuclease III; PFAM: HhH-GPD domain; Helix-hairpin-helix motif; Endonuclease III-like, iron-sulphur cluster loop motif; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Endonuclease III; TIGRFAM: Endonuclease III/Nth; IMG reference gene:2504586471; PFAM: HhH-GPD superfamily base excision DNA repair protein; Iron-sulfur binding domain of endonuclease III; Helix-hairpin-helix motif; TIGRFAM: endonuclease III YP_004413414.1 COGs: COG1246 N-acetylglutamate synthase and related acetyltransferase; InterPro IPR000182; KEGG: sth:STH2891 acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Acetyltransferase, GNAT family; IMG reference gene:2504586472; PFAM: Acetyltransferase (GNAT) family YP_004413415.1 COGs: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; InterPro IPR006218:IPR006268; KEGG: tmt:Tmath_1028 phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-7-phosphoheptulonate synthase; SPTR: 3-deoxy-7-phosphoheptulonate synthase; TIGRFAM: Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2; IMG reference gene:2504586473; PFAM: DAHP synthetase I family; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase YP_004413416.1 COGs: COG0287 Prephenate dehydrogenase; InterPro IPR003099; KEGG: gur:Gura_1463 prephenate dehydrogenase; PFAM: Prephenate dehydrogenase; PRIAM: Prephenate dehydrogenase; SPTR: Prephenate dehydrogenase; IMG reference gene:2504586474; PFAM: Prephenate dehydrogenase YP_004413417.1 KEGG: sus:Acid_3466 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586475; PFAM: Uncharacterised protein family (UPF0158) YP_004413418.1 COGs: COG0085 DNA-directed RNA polymerase beta subunit/140 kD subunit; InterProIPR010243:IPR007642:IPR007120:IPR007645:IPR 007641:IPR007644:IPR019462; KEGG: toc:Toce_0111 DNA-directed RNA polymerase subunit beta; PFAM: DNA-directed RNA polymerase, subunit 2, domain 6; RNA polymerase Rpb2, domain 2; RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 7; RNA polymerase, beta subunit, protrusion; DNA-directed RNA polymerase, beta subunit, external 1 domain; SPTR: DNA-directed RNA polymerase subunit beta; TIGRFAM: DNA-directed RNA polymerase, beta subunit, bacterial-type; IMG reference gene:2504586476; PFAM: RNA polymerase Rpb2, domain 3; RNA polymerase Rpb2, domain 6; RNA polymerase beta subunit external 1 domain; RNA polymerase Rpb2, domain 2; RNA polymerase beta subunit; RNA polymerase Rpb2, domain 7; TIGRFAM: DNA-directed RNA polymerase, beta subunit YP_004413419.1 COGs: COG0086 DNA-directed RNA polymerase beta' subunit/160 kD subunit; HAMAP: DNA-directed RNA polymerase, subunit beta-prime; InterProIPR012754:IPR007080:IPR000722:IPR007066:IPR 007083:IPR007081:IPR006592; KEGG: vpr:Vpar_1502 DNA-directed RNA polymerase, beta' subunit; PFAM: RNA polymerase Rpb1, domain 1; RNA polymerase, alpha subunit; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 5; SMART: RNA polymerase, N-terminal; SPTR: DNA-directed RNA polymerase subunit beta'; TIGRFAM: DNA-directed RNA polymerase, subunit beta-prime; IMG reference gene:2504586477; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb1, domain 4; RNA polymerase Rpb1, domain 1; RNA polymerase Rpb1, domain 3; RNA polymerase Rpb1, domain 5; TIGRFAM: DNA-directed RNA polymerase, beta' subunit, predominant form YP_004413420.1 COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: hor:Hore_14780 4-aminobutyrate aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Alanine--glyoxylate transaminase; SPTR: 4-aminobutyrate transaminase; IMG reference gene:2504586478; PFAM: Aminotransferase class-III YP_004413421.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: hor:Hore_14790 peptidase U32; PFAM: Peptidase U32; SPTR: Peptidase U32; IMG reference gene:2504586479; PFAM: Peptidase family U32 YP_004413422.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: bld:BLi02686 Zur; PFAM: Ferric-uptake regulator; SPTR: Transcriptional regulator ZurR; IMG reference gene:2504586480; PFAM: Ferric uptake regulator family YP_004413423.1 COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333:IPR001433:IPR019480; KEGG: vpr:Vpar_0567 oxidoreductase FAD/NAD(P)-binding domain protein; PFAM: Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; SPTR: Dihydroorotate dehydrogenase, electron transfer subunit; IMG reference gene:2504586481; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain YP_004413424.1 COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR005720:IPR012135; KEGG: gur:Gura_2150 dihydroorotate dehydrogenase 1B; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; SPTR: Dihydroorotate dehydrogenase; TIGRFAM: Dihydroorotate dehydrogenase, class 1; IMG reference gene:2504586482; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein YP_004413425.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586483 YP_004413426.1 COGs: COG2309 Leucyl aminopeptidase (aminopeptidase T); InterPro IPR000787; KEGG: dhd:Dhaf_2902 peptidase M29 aminopeptidase II; PFAM: Peptidase M29, aminopeptidase II; SPTR: Aminopeptidase PepS; IMG reference gene:2504586484; PFAM: Thermophilic metalloprotease (M29) YP_004413427.1 KEGG: cst:CLOST_1052 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586486 YP_004413428.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586487 YP_004413429.1 COGs: COG1555 DNA uptake protein and related DNA-binding protein; InterPro IPR003583:IPR000445:IPR019554:IPR004509; KEGG: toc:Toce_0773 competence protein ComEA helix-hairpin-helix repeat protein; PFAM: Soluble ligand binding domain; Helix-hairpin-helix motif; SMART: Helix-hairpin-helix DNA-binding motif, class 1; SPTR: Competence protein; TIGRFAM: Competence protein ComEA, helix-hairpin-helix domain; IMG reference gene:2504586488; PFAM: SLBB domain; Helix-hairpin-helix motif; TIGRFAM: competence protein ComEA helix-hairpin-helix repeat region; comEA protein YP_004413430.1 COGs: COG2333 hydrolase (metallo-beta-lactamase superfamily); InterPro IPR004797:IPR004477:IPR001279; KEGG: pth:PTH_0857 hydrolase; PFAM: ComEC/Rec2-related protein; Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: DNA internalization-related competence protein ComEC/Rec2; TIGRFAM: Competence protein ComEC/Rec2; ComEC/Rec2-related protein; IMG reference gene:2504586489; PFAM: Competence protein; Metallo-beta-lactamase superfamily; TIGRFAM: ComEC/Rec2-related protein; DNA internalization-related competence protein ComEC/Rec2 YP_004413431.1 COGs: COG1216 glycosyltransferase; InterPro IPR001173; KEGG: dhd:Dhaf_4180 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Putative glycosyltransferase; IMG reference gene:2504586490; PFAM: Glycosyl transferase family 2 YP_004413432.1 InterPro IPR018770:IPR007829; KEGG: cce:Ccel_1421 TM2 domain containing protein; PFAM: 5-bromo-4-chloroindolyl phosphate hydrolysis protein; TM2; SPTR: Conserved domain protein; IMG reference gene:2504586491; PFAM: TM2 domain; 5-bromo-4-chloroindolyl phosphate hydrolysis protein YP_004413433.1 COGs: COG3853 Uncharacterized protein involved in tellurite resistance; InterPro IPR008863; KEGG: cpy:Cphy_1971 toxic anion resistance family protein; PFAM: Toxic anion resistance; SPTR: Putative tellurite resistance protein; IMG reference gene:2504586492; PFAM: Toxic anion resistance protein (TelA) YP_004413434.1 COGs: COG0041 Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase; InterPro IPR000031; KEGG: afn:Acfer_1281 phosphoribosylaminoimidazole carboxylase, catalytic subunit; PFAM: Phosphoribosylaminoimidazole carboxylase, core; PRIAM: Phosphoribosylaminoimidazole carboxylase; SPTR: Phosphoribosylaminoimidazole carboxylase, catalytic subunit; TIGRFAM: Phosphoribosylaminoimidazole carboxylase, core; IMG reference gene:2504586493; PFAM: AIR carboxylase; TIGRFAM: phosphoribosylaminoimidazole carboxylase, PurE protein YP_004413435.1 COGs: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; InterPro IPR001636; KEGG: tle:Tlet_1916 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase; PRIAM: Phosphoribosylaminoimidazolesuccinocarboxamide synthase; SPTR: Phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: SAICAR synthetase; IMG reference gene:2504586494; PFAM: SAICAR synthetase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase YP_004413436.1 COGs: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; InterPro IPR004733:IPR010918:IPR000728; KEGG: afn:Acfer_1279 phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase-related protein, C-terminal; AIR synthase-related protein; PRIAM: Phosphoribosylformylglycinamidine cyclo-ligase; SPTR: Phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; IMG reference gene:2504586495; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylaminoimidazole synthetase YP_004413437.1 COGs: COG0299 Folate-dependent phosphoribosylglycinamide formyltransferase PurN; InterPro IPR002376:IPR004607; KEGG: drm:Dred_2363 phosphoribosylglycinamide formyltransferase; PFAM: Formyl transferase, N-terminal; PRIAM: Phosphoribosylglycinamide formyltransferase; SPTR: Phosphoribosylglycinamide formyltransferase; TIGRFAM: Phosphoribosylglycinamide formyltransferase; IMG reference gene:2504586496; PFAM: Formyl transferase; TIGRFAM: phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent YP_004413438.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR011607:IPR013982; KEGG: afn:Acfer_1277 IMP cyclohydrolase; PFAM: Methylglyoxal synthase-like domain; AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: Methylglyoxal synthase-like domain; SPTR: Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; IMG reference gene:2504586497; PFAM: AICARFT/IMPCHase bienzyme; MGS-like domain YP_004413439.1 SPTR: Chaperonin 2; IMG reference gene:2504586498 YP_004413440.1 COGs: COG0151 Phosphoribosylamine-glycine ligase; InterPro IPR000115:IPR020561:IPR020562:IPR020560; KEGG: afn:Acfer_1276 phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; PRIAM: Phosphoribosylamine--glycine ligase; SPTR: Phosphoribosylamine--glycine ligase; TIGRFAM: Phosphoribosylglycinamide synthetase; IMG reference gene:2504586500; PFAM: Phosphoribosylglycinamide synthetase, N domain; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, C domain; TIGRFAM: phosphoribosylamine--glycine ligase YP_004413441.1 COGs: COG1026 Zn-dependent peptidase insulinase-like; InterPro IPR011765:IPR007863:IPR013578; KEGG: cbi:CLJ_B3592 peptidase family protein; PFAM: Peptidase M16C associated; Peptidase M16, C-terminal; Peptidase M16, N-terminal; SPTR: Peptidase, M16 family; IMG reference gene:2504586501; PFAM: Peptidase M16C associated; Peptidase M16 inactive domain; Insulinase (Peptidase family M16) YP_004413442.1 COGs: COG0329 Dihydrodipicolinate synthase/N-acetylneuraminate lyase; InterPro IPR005263:IPR002220; KEGG: cbe:Cbei_4776 dihydrodipicolinate synthase; PFAM: Dihydrodipicolinate synthetase; PRIAM: Dihydrodipicolinate synthase; SPTR: Dihydrodipicolinate synthase; TIGRFAM: Dihydrodipicolinate synthase subfamily; IMG reference gene:2504586502; PFAM: Dihydrodipicolinate synthetase family; TIGRFAM: dihydrodipicolinate synthase YP_004413443.1 SPTR: Putative coenzyme F(420) biosynthesis enzyme; IMG reference gene:2504586503 YP_004413444.1 COGs: COG2832 conserved hypothetical protein; InterPro IPR007401; KEGG: vpr:Vpar_1345 protein of unknown function DUF454; PFAM: Protein of unknown function DUF454; SPTR: Putative membrane protein; IMG reference gene:2504586504; PFAM: Protein of unknown function (DUF454) YP_004413445.1 COGs: COG5009 Membrane carboxypeptidase/penicillin-binding protein; InterPro IPR001264; KEGG: vpr:Vpar_1064 penicillin-binding protein, 1A family; PFAM: Glycosyl transferase, family 51; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Penicillin-binding protein 1A; IMG reference gene:2504586505; PFAM: Transglycosylase YP_004413446.1 InterPro IPR018841; KEGG: pph:Ppha_2376 hypothetical protein; PFAM: Protein of unknown function DUF2442; SPTR: Putative uncharacterized protein mobA; IMG reference gene:2504586506; PFAM: Protein of unknown function (DUF2442) YP_004413447.1 KEGG: cli:Clim_1341 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586507 YP_004413448.1 COGs: COG0002 Acetylglutamate semialdehyde dehydrogenase; InterPro IPR000706:IPR000534:IPR012280; KEGG: pth:PTH_0501 N-acetyl-gamma-glutamyl-phosphate reductase; PFAM: Semialdehyde dehydrogenase, NAD-binding; Semialdehyde dehydrogenase, dimerisation domain; PRIAM: N-acetyl-gamma-glutamyl-phosphate reductase; SMART: Semialdehyde dehydrogenase, NAD-binding; SPTR: N-acetyl-gamma-glutamyl-phosphate reductase; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, type 1; IMG reference gene:2504586508; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: N-acetyl-gamma-glutamyl-phosphate reductase, common form YP_004413449.1 COGs: COG1364 N-acetylglutamate synthase (N-acetylornithine aminotransferase); InterPro IPR002813; KEGG: tjr:TherJR_0347 arginine biosynthesis bifunctional protein ArgJ; PFAM: Arginine biosynthesis protein ArgJ; PRIAM: Amino-acid N-acetyltransferase; SPTR: Glutamate N-acetyltransferase/amino-acid acetyltransferase; TIGRFAM: Arginine biosynthesis protein ArgJ; IMG reference gene:2504586509; PFAM: ArgJ family; TIGRFAM: glutamate N-acetyltransferase/amino-acid acetyltransferase YP_004413450.1 COGs: COG0548 Acetylglutamate kinase; InterPro IPR004662:IPR001048; KEGG: afn:Acfer_0595 acetylglutamate kinase; PFAM: Aspartate/glutamate/uridylate kinase; PRIAM: Acetylglutamate kinase; SPTR: Acetylglutamate kinase; TIGRFAM: Acetylglutamate kinase; IMG reference gene:2504586510; PFAM: Amino acid kinase family; TIGRFAM: acetylglutamate kinase YP_004413451.1 COGs: COG4992 Ornithine/acetylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; InterPro IPR004636:IPR005814; KEGG: afn:Acfer_0596 acetylornithine and succinylornithine aminotransferase; PFAM: Aminotransferase class-III; PRIAM: Acetylornithine transaminase; SPTR: Acetylornithine transaminase; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; IMG reference gene:2504586511; PFAM: Aminotransferase class-III; TIGRFAM: acetylornithine and succinylornithine aminotransferases YP_004413452.1 COGs: COG0078 Ornithine carbamoyltransferase; InterPro IPR002292:IPR006132:IPR006131; KEGG: drm:Dred_0276 ornithine carbamoyltransferase; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Ornithine carbamoyltransferase; SPTR: Ornithine carbamoyltransferase; TIGRFAM: Ornithine carbamoyltransferase; IMG reference gene:2504586512; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: ornithine carbamoyltransferase YP_004413453.1 COGs: COG0137 Argininosuccinate synthase; InterPro IPR001518; KEGG: hmo:HM1_1436 argininosuccinate synthase; PFAM: Argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: Argininosuccinate synthase; IMG reference gene:2504586513; PFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase YP_004413454.1 COGs: COG0165 Argininosuccinate lyase; InterPro IPR022761:IPR009049; KEGG: vpr:Vpar_1567 argininosuccinate lyase; PFAM: Lyase 1, N-terminal; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: Argininosuccinate lyase; IMG reference gene:2504586514; PFAM: Lyase; TIGRFAM: argininosuccinate lyase YP_004413455.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: amt:Amet_3876 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504586515; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_004413456.1 KEGG: afn:Acfer_0607 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586516 YP_004413457.1 COGs: COG0598 Mg2+ and Co2+ transporter; InterPro IPR002523; KEGG: dhd:Dhaf_3494 Mg2 transporter protein CorA family protein; PFAM: Mg2+ transporter protein, CorA-like; SPTR: Magnesium transporter, CorA family; IMG reference gene:2504586517; PFAM: CorA-like Mg2+ transporter protein YP_004413458.1 COGs: COG3581 conserved hypothetical protein; InterPro IPR018709:IPR008275:IPR010327:IPR002731; KEGG: ccv:CCV52592_1797 CoA-substrate-specific enzyme activase domain-containing protein; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; 2-hydroxyglutaryl-CoA dehydratase, D-component; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: BadF/BadG/BcrA/BcrD ATPase family protein; TIGRFAM: CoA enzyme activase; IMG reference gene:2504586518; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative YP_004413459.1 COGs: COG2733 membrane protein; InterPro IPR007383; KEGG: dae:Dtox_1997 protein of unknown function DUF445; PFAM: Protein of unknown function DUF445, transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504586519; PFAM: Protein of unknown function (DUF445) YP_004413460.1 COGs: COG2733 membrane protein; InterPro IPR007383; KEGG: hmo:HM1_1667 hypothetical protein; PFAM: Protein of unknown function DUF445, transmembrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504586520; PFAM: Protein of unknown function (DUF445) YP_004413461.1 InterPro IPR001440:IPR013105:IPR019734; KEGG: pmt:PMT0296 TPR repeat-containing protein; PFAM: Tetratricopeptide TPR2; Tetratricopeptide TPR-1; SPTR: Putative TPR repeat-containing domain protein; IMG reference gene:2504586521; PFAM: Tetratricopeptide repeat YP_004413462.1 COGs: COG1586 S-adenosylmethionine decarboxylase; InterPro IPR017716:IPR003826; KEGG: afn:Acfer_1468 S-adenosylmethionine decarboxylase related protein; PFAM: S-adenosylmethionine decarboxylase, bacterial/archaeal; SPTR: S-adenosylmethionine decarboxylase proenzyme; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme; IMG reference gene:2504586522; PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Bacillus form YP_004413463.1 COGs: COG0775 Nucleoside phosphorylase; InterPro IPR000845; KEGG: aci:ACIAD0773 putative MTA/SAH nucleosidase; PFAM: Nucleoside phosphorylase domain; SPTR: Putative MTA/SAH nucleosidase; IMG reference gene:2504586523; PFAM: Phosphorylase superfamily YP_004413464.1 COGs: COG2831 Hemolysin activation/secretion protein; InterPro IPR000184; KEGG: hse:Hsero_0306 hemolysin activation/secretion protein; PFAM: Bacterial surface antigen (D15); SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504586525; PFAM: Surface antigen YP_004413465.1 InterPro IPR008638:IPR011102; KEGG: dar:Daro_2106 filamentous haemagglutinin, N-terminal; PFAM: Filamentous haemagglutinin, N-terminal, bacterial; SMART: Signal transduction histidine kinase, HWE region; SPTR: Putative filamentous hemagglutinin family protein; TIGRFAM: Filamentous haemagglutinin, N-terminal, bacterial; IMG reference gene:2504586526; PFAM: haemagglutination activity domain; TIGRFAM: filamentous haemagglutinin family N-terminal domain YP_004413466.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: cce:Ccel_3266 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504586527; PFAM: Transposase IS200 like YP_004413467.1 COGs: COG0289 Dihydrodipicolinate reductase; HAMAP: Dihydrodipicolinate reductase, bacterial/plant; InterPro IPR011770:IPR000846:IPR022663; KEGG: hmo:HM1_2327 dihydrodipicolinate reductase; PFAM: Dihydrodipicolinate reductase, C-terminal; Dihydrodipicolinate reductase, N-terminal; PRIAM: Dihydrodipicolinate reductase; SPTR: Dihydrodipicolinate reductase; TIGRFAM: Dihydrodipicolinate reductase, bacterial/plant; IMG reference gene:2504586528; PFAM: Dihydrodipicolinate reductase, N-terminus; Dihydrodipicolinate reductase, C-terminus; TIGRFAM: dihydrodipicolinate reductase YP_004413468.1 COGs: COG0136 Aspartate-semialdehyde dehydrogenase; InterPro IPR005986:IPR000534:IPR012280; KEGG: afn:Acfer_1195 aspartate-semialdehyde dehydrogenase; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD-binding; PRIAM: Aspartate-semialdehyde dehydrogenase; SMART: Semialdehyde dehydrogenase, NAD-binding; SPTR: Aspartate-semialdehyde dehydrogenase; TIGRFAM: Aspartate-semialdehyde dehydrogenase, bacterial; IMG reference gene:2504586529; PFAM: Semialdehyde dehydrogenase, dimerisation domain; Semialdehyde dehydrogenase, NAD binding domain; TIGRFAM: aspartate-semialdehyde dehydrogenase (peptidoglycan organisms) YP_004413469.1 COGs: COG4472 conserved hypothetical protein; InterPro IPR009309; KEGG: hmo:HM1_0531 hypothetical protein; PFAM: Uncharacterised protein family UPF0297; SPTR: Putative uncharacterized protein; IMG reference gene:2504586530; PFAM: Bacterial protein of unknown function (DUF965) YP_004413470.1 COGs: COG0816 endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis); HAMAP: Resolvase, holliday junction-type, YqgF-like; InterPro IPR005227:IPR006641; KEGG: vpr:Vpar_1179 Holliday junction resolvase YqgF; PFAM: Resolvase, holliday junction-type, YqgF-like; SMART: Resolvase, RNase H-like fold; SPTR: Putative Holliday junction resolvase; TIGRFAM: Resolvase, holliday junction-type, YqgF-like; IMG reference gene:2504586531; PFAM: Uncharacterised protein family (UPF0081); TIGRFAM: RNAse H-fold protein YqgF YP_004413471.1 InterPro IPR009711; KEGG: afn:Acfer_0898 protein of unknown function DUF1292; PFAM: Uncharacterised protein family UPF0473; SPTR: Putative uncharacterized protein; IMG reference gene:2504586532; PFAM: Protein of unknown function (DUF1292) YP_004413472.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586533 YP_004413473.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586534 YP_004413474.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586535 YP_004413475.1 SPTR: Putative MoaD; IMG reference gene:2504586536 YP_004413476.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586537 YP_004413477.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504586538 YP_004413478.1 COGs: COG1559 periplasmic solute-binding protein; InterPro IPR003770; KEGG: vpr:Vpar_1177 aminodeoxychorismate lyase; PFAM: Uncharacterised protein family UPF0755; SPTR: Aminodeoxychorismate lyase; TIGRFAM: Uncharacterised protein family UPF0755; IMG reference gene:2504586539; PFAM: YceG-like family; TIGRFAM: conserved hypothetical protein, YceG family YP_004413479.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: afn:Acfer_0900 peptidase U32; PFAM: Peptidase U32; SPTR: Peptidase, U32 family; IMG reference gene:2504586540; PFAM: Peptidase family U32 YP_004413480.1 COGs: COG1254 Acylphosphatase; InterPro IPR001792; KEGG: csh:Closa_1868 acylphosphatase; PFAM: Acylphosphatase-like; SPTR: Acylphosphatase; IMG reference gene:2504586541; PFAM: Acylphosphatase YP_004413481.1 COGs: COG0757 3-dehydroquinate dehydratase II; HAMAP: Dehydroquinase, class II; InterPro IPR001874; KEGG: sth:STH1866 3-dehydroquinate dehydratase; PFAM: Dehydroquinase, class II; PRIAM: 3-dehydroquinate dehydratase; SPTR: 3-dehydroquinate dehydratase, type II; TIGRFAM: Dehydroquinase, class II; IMG reference gene:2504586542; PFAM: Dehydroquinase class II; TIGRFAM: 3-dehydroquinate dehydratase, type II YP_004413482.1 COGs: COG0006 Xaa-Pro aminopeptidase; InterPro IPR000587:IPR000994; KEGG: tte:TTE1280 Xaa-Pro aminopeptidase; PFAM: Peptidase M24, structural domain; Creatinase; SPTR: Xaa-Pro dipeptidase; IMG reference gene:2504586543; PFAM: Metallopeptidase family M24; Creatinase/Prolidase N-terminal domain YP_004413483.1 COGs: COG0231 Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A); InterPro IPR015365:IPR013185:IPR011768:IPR001059; KEGG: afn:Acfer_0902 translation elongation factor P; PFAM: Translation elongation factor, KOW-like; Elongation factor P, C-terminal; Translation elongation factor P/YeiP, central; SMART: Elongation factor P, C-terminal; SPTR: Elongation factor P; TIGRFAM: Translation elongation factor P; IMG reference gene:2504586544; PFAM: Elongation factor P, C-terminal; Elongation factor P (EF-P) KOW-like domain; Elongation factor P (EF-P) OB domain; TIGRFAM: translation elongation factor P YP_004413484.1 COGs: COG1302 conserved hypothetical protein; InterPro IPR005531; KEGG: toc:Toce_1314 protein of unknown function DUF322; PFAM: Alkaline shock protein Asp23; SPTR: Alkaline shock protein 23; IMG reference gene:2504586545; PFAM: Protein of unknown function (DUF322) YP_004413485.1 KEGG: sth:STH1851 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586546 YP_004413486.1 InterPro IPR018730; KEGG: swo:Swol_0563 hypothetical protein; PFAM: Protein of unknown function DUF2273; SPTR: Putative uncharacterized protein; IMG reference gene:2504586547; PFAM: Small integral membrane protein (DUF2273) YP_004413487.1 COGs: COG0781 Transcription termination factor; HAMAP: NusB antitermination factor; InterPro IPR011605:IPR006027; KEGG: afn:Acfer_0846 NusB antitermination factor; PFAM: NusB/RsmB/TIM44; SPTR: N utilization substance protein B homolog; TIGRFAM: NusB antitermination factor; IMG reference gene:2504586548; PFAM: NusB family; TIGRFAM: transcription antitermination factor NusB YP_004413488.1 COGs: COG1570 Exonuclease VII large subunit; HAMAP: Exonuclease VII, large subunit; InterPro IPR003753:IPR004365:IPR020579; KEGG: cce:Ccel_1904 exodeoxyribonuclease VII, large subunit; PFAM: Exonuclease VII, large subunit, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SPTR: Exodeoxyribonuclease 7 large subunit; TIGRFAM: Exonuclease VII, large subunit; IMG reference gene:2504586549; PFAM: Exonuclease VII, large subunit; OB-fold nucleic acid binding domain; TIGRFAM: exodeoxyribonuclease VII, large subunit YP_004413489.1 HAMAP: Exonuclease VII, small subunit; InterPro IPR003761; KEGG: pag:PLES_09341 exodeoxyribonuclease VII small subunit; PFAM: Exonuclease VII, small subunit; SPTR: Exodeoxyribonuclease 7 small subunit; TIGRFAM: Exonuclease VII, small subunit; IMG reference gene:2504586550; PFAM: Exonuclease VII small subunit; TIGRFAM: exodeoxyribonuclease VII, small subunit YP_004413490.1 COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: pth:PTH_1194 geranylgeranyl pyrophosphate synthase; PFAM: Polyprenyl synthetase; SPTR: Geranyltranstransferase; IMG reference gene:2504586551; PFAM: Polyprenyl synthetase YP_004413491.1 COGs: COG1154 Deoxyxylulose-5-phosphate synthase; HAMAP: Deoxyxylulose-5-phosphate synthase; InterPro IPR005477:IPR005475:IPR005476; KEGG: adg:Adeg_1398 deoxyxylulose-5-phosphate synthase; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: 1-deoxy-D-xylulose-5-phosphate synthase; TIGRFAM: Deoxyxylulose-5-phosphate synthase; IMG reference gene:2504586552; PFAM: Dehydrogenase E1 component; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: 1-deoxy-D-xylulose-5-phosphate synthase YP_004413492.1 COGs: COG1189 rRNA methylase; InterPro IPR002942:IPR004538:IPR002877; KEGG: afn:Acfer_0852 hemolysin A; PFAM: Ribosomal RNA methyltransferase RrmJ/FtsJ; RNA-binding S4; SMART: RNA-binding S4; SPTR: Hemolysin A; TIGRFAM: Haemolysin A; IMG reference gene:2504586553; PFAM: S4 domain; FtsJ-like methyltransferase; TIGRFAM: hemolysin TlyA family protein YP_004413493.1 COGs: COG0061 sugar kinase; InterPro IPR002504; KEGG: toc:Toce_1304 ATP-NAD/AcoX kinase; PFAM: Inorganic polyphosphate/ATP-NAD kinase, predicted; SPTR: Probable inorganic polyphosphate/ATP-NAD kinase; IMG reference gene:2504586554; PFAM: ATP-NAD kinase YP_004413494.1 COGs: COG1438 Arginine repressor; InterPro IPR020900:IPR020899:IPR001669; KEGG: sth:STH1836 transcriptional regulator; PFAM: Arginine repressor, C-terminal; Arginine repressor, DNA-binding domain; SPTR: Arginine repressor; TIGRFAM: Arginine repressor; IMG reference gene:2504586555; PFAM: Arginine repressor, C-terminal domain; Arginine repressor, DNA binding domain; TIGRFAM: arginine repressor YP_004413495.1 COGs: COG0497 ATPase involved in DNA repair; InterPro IPR004604:IPR003395; KEGG: bss:BSUW23_11995 double strand breaks DNA repair and genetic recombination protein; PFAM: RecF/RecN/SMC; SPTR: DNA repair protein RecN; TIGRFAM: DNA recombination/repair protein RecN; IMG reference gene:2504586556; PFAM: RecF/RecN/SMC N terminal domain; TIGRFAM: DNA repair protein RecN YP_004413496.1 InterPro IPR000086; KEGG: rmr:Rmar_1927 NUDIX hydrolase; PFAM: NUDIX hydrolase domain; SPTR: ADP-ribose pyrophosphatase(Adenosine diphosphoribose pyrophosphatase); IMG reference gene:2504586557; PFAM: NUDIX domain YP_004413497.1 COGs: COG1994 Zn-dependent protease; InterPro IPR008915; KEGG: tpd:Teth39_1128 peptidase M50; PFAM: Peptidase M50; SPTR: Peptidase, M50 family; IMG reference gene:2504586558; PFAM: Peptidase family M50 YP_004413498.1 COGs: COG1354 conserved hypothetical protein; InterPro IPR003768; KEGG: tjr:TherJR_1637 chromosome segregation and condensation protein ScpA; PFAM: Prokaryotic chromosome segregation/condensation protein ScpA; SPTR: Segregation and condensation protein A; manually curated; IMG reference gene:2504586559; PFAM: ScpA/B protein YP_004413499.1 COGs: COG1386 transcriptional regulator protein containing the HTH domain; InterPro IPR005234; KEGG: afn:Acfer_1244 chromosome segregation and condensation protein, ScpB; PFAM: Chromosome segregation/condensation protein ScpB, prokaryote; SPTR: Segregation and condensation protein B; TIGRFAM: Chromosome segregation/condensation protein ScpB, prokaryote; IMG reference gene:2504586560; PFAM: Putative transcriptional regulators (Ypuh-like); TIGRFAM: segregation and condensation protein B YP_004413500.1 COGs: COG0826 Collagenase and related protease; InterPro IPR001539; KEGG: afn:Acfer_1284 peptidase U32; PFAM: Peptidase U32; SPTR: Protease; IMG reference gene:2504586561; PFAM: Collagenase; Peptidase family U32 YP_004413501.1 COGs: COG1193 Mismatch repair ATPase (MutS family); InterPro IPR005747:IPR002625:IPR000432:IPR007696; KEGG: gwc:GWCH70_2632 recombination and DNA strand exchange inhibitor protein; PFAM: DNA mismatch repair protein MutS, C-terminal; Smr protein/MutS2 C-terminal; SMART: DNA mismatch repair protein MutS, C-terminal; Smr protein/MutS2 C-terminal; DNA mismatch repair protein MutS, core; SPTR: MutS2 protein; TIGRFAM: DNA mismatch repair protein MutS, type 2; IMG reference gene:2504586562; PFAM: MutS domain V; Smr domain; TIGRFAM: MutS2 family protein YP_004413502.1 COGs: COG0744 Membrane carboxypeptidase (penicillin-binding protein); InterPro IPR001460:IPR011816:IPR001264; KEGG: vpr:Vpar_1064 penicillin-binding protein, 1A family; PFAM: Glycosyl transferase, family 51; Penicillin-binding protein, transpeptidase; SPTR: Penicillin-binding protein, 1A family; TIGRFAM: Penicillin-binding protein 1A; IMG reference gene:2504586563; PFAM: Penicillin binding protein transpeptidase domain; Transglycosylase; TIGRFAM: penicillin-binding protein, 1A family YP_004413503.1 COGs: COG0162 Tyrosyl-tRNA synthetase; HAMAP: Tyrosyl-tRNA synthetase, class Ib; InterPro IPR002307:IPR002305:IPR002942; KEGG: afn:Acfer_0828 tyrosyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ib; RNA-binding S4; PRIAM: Tyrosine--tRNA ligase; SMART: RNA-binding S4; SPTR: Tyrosyl-tRNA synthetase; TIGRFAM: Tyrosyl-tRNA synthetase, class Ib; IMG reference gene:2504586564; PFAM: S4 domain; tRNA synthetases class I (W and Y); TIGRFAM: tyrosyl-tRNA synthetase YP_004413504.1 COGs: COG0217 conserved hypothetical protein; InterPro IPR002876; KEGG: afn:Acfer_1531 protein of unknown function DUF28; PFAM: Protein of unknown function DUF28; SPTR: UPF0082 protein SELSPUOL_01162; TIGRFAM: Protein of unknown function DUF28; IMG reference gene:2504586565; PFAM: Domain of unknown function DUF28; TIGRFAM: DNA-binding regulatory protein, YebC/PmpR family YP_004413505.1 COGs: COG0817 Holliday junction resolvasome endonuclease subunit; InterPro IPR002176; KEGG: vpr:Vpar_0590 crossover junction endodeoxyribonuclease RuvC; PFAM: Crossover junction endodeoxyribonuclease RuvC; PRIAM: Crossover junction endodeoxyribonuclease; SPTR: Crossover junction endodeoxyribonuclease ruvC; TIGRFAM: Crossover junction endodeoxyribonuclease RuvC; IMG reference gene:2504586566; PFAM: Crossover junction endodeoxyribonuclease RuvC; TIGRFAM: crossover junction endodeoxyribonuclease RuvC YP_004413506.1 COGs: COG0632 Holliday junction resolvasome DNA-binding subunit; InterPro IPR003583:IPR013849:IPR000085:IPR011114; KEGG: vpr:Vpar_0591 Holliday junction DNA helicase RuvA; PFAM: DNA helicase, Holliday junction RuvA type, domain I, bacterial; DNA helicase, Holliday junction RuvA type, domain III, C-terminal; SPTR: Holliday junction ATP-dependent DNA helicase ruvA; TIGRFAM: Bacterial DNA recombination protein RuvA; IMG reference gene:2504586567; PFAM: RuvA, C-terminal domain; RuvA N terminal domain; TIGRFAM: Holliday junction DNA helicase, RuvA subunit YP_004413507.1 COGs: COG2255 Holliday junction resolvasome helicase subunit; InterPro IPR004605:IPR003593:IPR008823:IPR008824; KEGG: vpr:Vpar_0592 Holliday junction DNA helicase RuvB; PFAM: DNA helicase, Holliday junction RuvB type, N-terminal; DNA helicase, Holliday junction RuvB type, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: Holliday junction ATP-dependent DNA helicase ruvB; TIGRFAM: DNA helicase, Holliday junction RuvB type; IMG reference gene:2504586568; PFAM: Holliday junction DNA helicase ruvB C-terminus; Holliday junction DNA helicase ruvB N-terminus; TIGRFAM: Holliday junction DNA helicase, RuvB subunit YP_004413508.1 COGs: COG1636 conserved hypothetical protein; InterPro IPR003828; KEGG: tjr:TherJR_1183 protein of unknown function DUF208; PFAM: Protein of unknown function DUF208; SPTR: Putative DNA integration/recombination/invertion protein; IMG reference gene:2504586569; PFAM: Uncharacterized BCR, COG1636 YP_004413509.1 COGs: COG3589 conserved hypothetical protein; InterPro IPR008589; KEGG: cbe:Cbei_1919 hypothetical protein; PFAM: Protein of unknown function DUF871, prokaryotic; SPTR: Outer surface protein; IMG reference gene:2504586570; PFAM: Bacterial protein of unknown function (DUF871) YP_004413510.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR003352:IPR018113; KEGG: afn:Acfer_0138 phosphotransferase system EIIC; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system EIIB/cysteine, phosphorylation site; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: Phosphotransferase system PTS, EIIB domain,Phosphotransferase system, EIIC; IMG reference gene:2504586571; PFAM: Phosphotransferase system, EIIC; phosphotransferase system, EIIB YP_004413511.1 COGs: COG2103 sugar phosphate isomerase; InterPro IPR005488:IPR001347; KEGG: cbe:Cbei_1917 N-acetylmuramic acid-6-phosphate etherase; PFAM: Sugar isomerase (SIS); SPTR: N-acetylmuramic acid 6-phosphate etherase; TIGRFAM: N-acetylmuramic acid 6-phosphate etherase; IMG reference gene:2504586572; PFAM: SIS domain; TIGRFAM: N-acetylmuramic acid 6-phosphate etherase YP_004413512.1 KEGG: afn:Acfer_1413 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586573 YP_004413513.1 COGs: COG1376 conserved hypothetical protein; InterPro IPR005490; KEGG: ttm:Tthe_1098 ErfK/YbiS/YcfS/YnhG family protein; PFAM: YkuD domain; SPTR: ErfK/YbiS/YcfS/YnhG family protein; IMG reference gene:2504586574; PFAM: L,D-transpeptidase catalytic domain YP_004413514.1 COGs: COG0749 DNA polymerase I - 3'-5' exonuclease and polymerase domains; InterProIPR018320:IPR020046:IPR020047:IPR001098:IPR 002421:IPR008918; KEGG: afn:Acfer_0443 DNA polymerase I; PFAM: DNA-directed DNA polymerase, family A, palm domain; 5'-3' exonuclease, alpha-helical arch, N-terminal; 5'-3' exonuclease, SAM-fold domain; SMART: 5'-3' exonuclease, N-terminal; Helix-hairpin-helix motif, class 2; DNA-directed DNA polymerase, family A, palm domain; SPTR: DNA polymerase I; TIGRFAM: DNA polymerase 1; IMG reference gene:2504586575; PFAM: 5'-3' exonuclease, C-terminal SAM fold; 5'-3' exonuclease, N-terminal resolvase-like domain; DNA polymerase family A; TIGRFAM: DNA polymerase I YP_004413515.1 COGs: COG0266 Formamidopyrimidine-DNA glycosylase; InterProIPR012319:IPR000191:IPR001977:IPR015886:IPR 010663; KEGG: acl:ACL_0351 bifunctional formamidopyrimidine-DNA glycosylase/dephospho-CoA kinase; PFAM: Dephospho-CoA kinase; DNA glycosylase/AP lyase, H2TH DNA-binding; DNA glycosylase/AP lyase, catalytic domain; Zinc finger, DNA glycosylase/AP lyase/isoleucyl tRNA synthetase; PRIAM: DNA-formamidopyrimidine glycosylase., Dephospho-CoA kinase; SMART: DNA glycosylase/AP lyase, catalytic domain; SPTR: Formamidopyrimidine-DNA glycosylase; TIGRFAM: DNA glycosylase/AP lyase; Dephospho-CoA kinase; IMG reference gene:2504586576; PFAM: Dephospho-CoA kinase; Formamidopyrimidine-DNA glycosylase H2TH domain; Formamidopyrimidine-DNA glycosylase N-terminal domain; Zinc finger found in FPG and IleRS; TIGRFAM: formamidopyrimidine-DNA glycosylase (fpg); dephospho-CoA kinase YP_004413516.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: dhd:Dhaf_2473 lytic transglycosylase catalytic; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Soluble lytic murein transglycosylase; IMG reference gene:2504586577; PFAM: Transglycosylase SLT domain YP_004413517.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterProIPR006308:IPR004365:IPR004013:IPR011708:IPR 003141; KEGG: hmo:HM1_2272 DNA polymerase III, alpha subunit, gram-positive type; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit, Gram-positive type; IMG reference gene:2504586578; PFAM: DNA polymerase III polC-type N-terminus; PHP domain; Bacterial DNA polymerase III alpha subunit; OB-fold nucleic acid binding domain; TIGRFAM: DNA polymerase III, alpha chain, Gram-positive type YP_004413518.1 COGs: COG0621 2-methylthioadenine synthetase; InterProIPR005839:IPR013848:IPR006463:IPR007197:IPR 006638:IPR002792; KEGG: tte:TTE1356 (dimethylallyl)adenosine tRNA methylthiotransferase; PFAM: Radical SAM; Methylthiotransferase, N-terminal; Deoxyribonuclease/rho motif-related TRAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: tRNA-I(6)A37 thiotransferase enzyme MiaB; TIGRFAM: Methylthiotransferase; tRNA-i(6)A37 modification enzyme MiaB; IMG reference gene:2504586579; PFAM: TRAM domain; Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: tRNA-N(6)-(isopentenyl)adenosine-37 thiotransferase enzyme MiaB; radical SAM methylthiotransferase, MiaB/RimO family YP_004413519.1 COGs: COG0249 Mismatch repair ATPase (MutS family); InterProIPR007696:IPR007695:IPR000432:IPR005748:IPR 007861; KEGG: afn:Acfer_1212 DNA mismatch repair protein MutS; PFAM: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS-like, N-terminal; DNA mismatch repair protein MutS, core; DNA mismatch repair protein MutS, clamp; SMART: DNA mismatch repair protein MutS, C-terminal; DNA mismatch repair protein MutS, core; SPTR: DNA mismatch repair protein mutS; TIGRFAM: DNA mismatch repair protein MutS, type 1; IMG reference gene:2504586580; PFAM: MutS family domain IV; MutS domain V; MutS domain I; MutS domain III; TIGRFAM: DNA mismatch repair protein MutS YP_004413520.1 COGs: COG0323 DNA mismatch repair enzyme (predicted ATPase); InterPro IPR014763:IPR013507:IPR014790:IPR003594; KEGG: vpr:Vpar_0872 DNA mismatch repair protein MutL; PFAM: MutL, C-terminal, dimerisation; DNA mismatch repair protein, C-terminal; ATPase-like, ATP-binding domain; SMART: MutL, C-terminal, dimerisation; ATPase-like, ATP-binding domain; SPTR: DNA mismatch repair protein mutL; TIGRFAM: DNA mismatch repair protein, N-terminal; IMG reference gene:2504586581; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; MutL C terminal dimerisation domain; DNA mismatch repair protein, C-terminal domain; TIGRFAM: DNA mismatch repair protein MutL YP_004413521.1 InterPro IPR007536; KEGG: dau:Daud_0555 hypothetical protein; PFAM: Protein of unknown function DUF548; SPTR: Putative uncharacterized protein; IMG reference gene:2504586582; PFAM: Protein of unknown function (DUF548) YP_004413522.1 COGs: COG2159 metal-dependent hydrolase of the TIM-barrel fold; InterPro IPR006992; KEGG: afn:Acfer_0383 amidohydrolase 2; PFAM: Amidohydrolase 2; SPTR: Amidohydrolase family protein; IMG reference gene:2504586583; PFAM: Amidohydrolase YP_004413523.1 COGs: COG0242 N-formylmethionyl-tRNA deformylase; InterPro IPR000181; KEGG: tjr:TherJR_1797 peptide deformylase; PFAM: Formylmethionine deformylase; SPTR: Peptide deformylase; TIGRFAM: Formylmethionine deformylase; IMG reference gene:2504586584; PFAM: Polypeptide deformylase; TIGRFAM: peptide deformylase YP_004413524.1 COGs: COG0223 Methionyl-tRNA formyltransferase; InterPro IPR002376:IPR005794:IPR005793; KEGG: cce:Ccel_1529 methionyl-tRNA formyltransferase; PFAM: Formyl transferase, N-terminal; Formyl transferase, C-terminal; PRIAM: Methionyl-tRNA formyltransferase; SPTR: Methionyl-tRNA formyltransferase; TIGRFAM: Methionyl-tRNA formyltransferase; IMG reference gene:2504586585; PFAM: Formyl transferase; Formyl transferase, C-terminal domain; TIGRFAM: methionyl-tRNA formyltransferase YP_004413525.1 COGs: COG1852 conserved hypothetical protein; InterPro IPR002829; KEGG: afn:Acfer_0312 protein of unknown function DUF116; PFAM: Protein of unknown function DUF116; SPTR: Putative nucleotide-binding protein; IMG reference gene:2504586586; PFAM: Protein of unknown function DUF116 YP_004413526.1 COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678:IPR006027:IPR011023:IPR004573; KEGG: drm:Dred_1707 sun protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; NusB/RsmB/TIM44; SPTR: Ribosomal RNA small subunit methyltransferase B; TIGRFAM: Fmu, rRNA SAM-dependent methyltransferase; Nop2p; IMG reference gene:2504586587; PFAM: NOL1/NOP2/sun family; NusB family; TIGRFAM: ribosomal RNA small subunit methyltransferase RsmB; NOL1/NOP2/sun family putative RNA methylase; transcription antitermination factor NusB YP_004413527.1 COGs: COG0820 Fe-S-cluster redox enzyme; InterPro IPR007197:IPR004383:IPR006638; KEGG: sth:STH1351 hypothetical protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Ribosomal RNA large subunit methyltransferase N; TIGRFAM: Ribosomal RNA large subunit methyltransferase RlmN; IMG reference gene:2504586588; PFAM: Radical SAM superfamily; TIGRFAM: 23S rRNA m2A2503 methyltransferase YP_004413528.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253:IPR022128; KEGG: tjr:TherJR_1792 FHA domain containing protein; PFAM: Protein of unknown function DUF3662; Forkhead-associated (FHA) domain; SMART: Forkhead-associated (FHA) domain; SPTR: FHA domain containing protein; IMG reference gene:2504586589; PFAM: Protein of unknown function (DUF2662); FHA domain YP_004413529.1 COGs: COG1716 FOG: FHA domain; InterPro IPR000253; KEGG: dae:Dtox_2308 FHA domain-containing protein; PFAM: Forkhead-associated (FHA) domain; SMART: Forkhead-associated (FHA) domain; SPTR: FHA domain containing protein; IMG reference gene:2504586590; PFAM: FHA domain YP_004413530.1 COGs: COG0631 Serine/threonine protein phosphatase; InterPro IPR014045:IPR001932; KEGG: cth:Cthe_0573 protein serine/threonine phosphatases; PFAM: Protein phosphatase 2C, N-terminal; SMART: Protein phosphatase 2C-like; SPTR: Protein phosphatase 1; IMG reference gene:2504586591; PFAM: Protein phosphatase 2C YP_004413531.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: dae:Dtox_2306 cell cycle protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; IMG reference gene:2504586592; PFAM: Cell cycle protein YP_004413532.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR001460; KEGG: toc:Toce_0254 peptidoglycan glycosyltransferase; PFAM: Penicillin-binding protein, transpeptidase; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Peptidoglycan glycosyltransferase; IMG reference gene:2504586593; PFAM: Penicillin binding protein transpeptidase domain YP_004413533.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR005543:IPR017442:IPR002290; KEGG: vpr:Vpar_0853 serine/threonine protein kinase with PASTA sensor(s); PFAM: Serine/threonine-protein kinase-like domain; PASTA; PRIAM: Non-specific protein-tyrosine kinase; SMART: Serine/threonine-protein kinase domain; PASTA; SPTR: Serine/threonine-protein kinase PrkC; IMG reference gene:2504586594; PFAM: Protein kinase domain; PASTA domain YP_004413534.1 COGs: COG1162 GTPase; HAMAP: Ribosome biogenesis GTPase RsgA, putative; InterPro IPR004881; KEGG: tte:TTE1499 GTPase; PFAM: Ribosome biogenesis GTPase RsgA, putative; SPTR: Putative ribosome biogenesis GTPase RsgA; TIGRFAM: Ribosome biogenesis GTPase RsgA, putative; IMG reference gene:2504586595; PFAM: Protein of unknown function, DUF258; TIGRFAM: ribosome small subunit-dependent GTPase A YP_004413535.1 COGs: COG0036 Pentose-5-phosphate-3-epimerase; InterPro IPR000056; KEGG: dau:Daud_1586 ribulose-phosphate 3-epimerase; PFAM: Ribulose-phosphate 3-epimerase; PRIAM: Ribulose-phosphate 3-epimerase; SPTR: Ribulose-phosphate 3-epimerase; TIGRFAM: Ribulose-phosphate 3-epimerase; IMG reference gene:2504586596; PFAM: Ribulose-phosphate 3 epimerase family; TIGRFAM: ribulose-phosphate 3-epimerase YP_004413536.1 COGs: COG0603 PP-loop superfamily ATPase; InterPro IPR018317; KEGG: tjr:TherJR_0947 ExsB protein; PFAM: Queuosine synthesis; SPTR: 7-cyano-7-deazaguanine synthase; TIGRFAM: Queuosine synthesis; IMG reference gene:2504586597; PFAM: ExsB; TIGRFAM: queuosine biosynthesis protein QueC YP_004413537.1 COGs: COG1469 conserved hypothetical protein; InterPro IPR003801; KEGG: gur:Gura_4045 putative GTP cyclohydrolase; PFAM: GTP cyclohydrolase FolE2/MptA; PRIAM: GTP cyclohydrolase I; SPTR: GTP cyclohydrolase folE2; IMG reference gene:2504586598; PFAM: Uncharacterized ACR, COG1469 YP_004413538.1 InterPro IPR022791:IPR005242; KEGG: vpr:Vpar_0897 hypothetical protein; PFAM: Lysylphosphatidylglycerol synthetase/UPF0104; SPTR: Putative uncharacterized protein; IMG reference gene:2504586599; PFAM: Uncharacterised protein family (UPF0104); TIGRFAM: conserved hypothetical protein YP_004413539.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: vpr:Vpar_1564 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Glutathione ABC transporter, permease protein GsiC; IMG reference gene:2504586600; PFAM: Binding-protein-dependent transport system inner membrane component YP_004413540.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: vpr:Vpar_1563 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Nickel ABC transporter, permease protein; IMG reference gene:2504586601; PFAM: Binding-protein-dependent transport system inner membrane component YP_004413541.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: vpr:Vpar_1562 extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Dipeptide-binding protein; IMG reference gene:2504586602; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004413542.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR013563:IPR003439; KEGG: lba:Lebu_0026 ABC transporter related; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide ABC transporter, ATP-binding protein OppD; IMG reference gene:2504586603; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region YP_004413543.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR010066:IPR013563:IPR003439; KEGG: elm:ELI_4369 dipeptide ABC transporter; PFAM: ABC transporter-like; Oligopeptide/dipeptide ABC transporter, C-terminal; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Oligopeptide ABC transporter, ATP-binding protein OppF; TIGRFAM: Oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal; IMG reference gene:2504586604; PFAM: ABC transporter; Oligopeptide/dipeptide transporter, C-terminal region; TIGRFAM: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain YP_004413544.1 COGs: COG0534 Na+-driven multidrug efflux pump; InterPro IPR002528; KEGG: amt:Amet_1122 MATE efflux family protein; PFAM: Multi antimicrobial extrusion protein; SPTR: MATE efflux family protein; TIGRFAM: Multi antimicrobial extrusion protein; IMG reference gene:2504586605; PFAM: MatE; TIGRFAM: putative efflux protein, MATE family YP_004413545.1 InterPro IPR001119; KEGG: afn:Acfer_1670 S-layer domain protein; PFAM: S-layer homology domain; SPTR: Putative S-layer domain protein; IMG reference gene:2504586606; PFAM: S-layer homology domain YP_004413546.1 COGs: COG4496 conserved hypothetical protein; InterPro IPR013368:IPR000831; KEGG: vpr:Vpar_0424 TrpR like protein, YerC/YecD; PFAM: Trp repressor; SPTR: TrpR protein; TIGRFAM: TrpR homologue YerC/YecD; IMG reference gene:2504586607; PFAM: Trp repressor protein; TIGRFAM: TrpR-related protein YerC/YecD YP_004413547.1 COGs: COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis; HAMAP: ATP phosphoribosyltransferase regulatory subunit; InterPro IPR004517:IPR002314; KEGG: hmo:HM1_3053 histidyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; PRIAM: Histidine--tRNA ligase; SPTR: ATP phosphoribosyltransferase, regulatory subunit; TIGRFAM: Histidyl-tRNA synthetase, class IIa, putative; IMG reference gene:2504586608; PFAM: tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: ATP phosphoribosyltransferase, regulatory subunit; histidyl-tRNA synthetase YP_004413548.1 KEGG: amt:Amet_3691 putative metal dependent phosphohydrolase; SPTR: Putative uncharacterized protein; IMG reference gene:2504586609; PFAM: HD domain YP_004413549.1 COGs: COG0040 ATP phosphoribosyltransferase; InterPro IPR013820; KEGG: afn:Acfer_0916 ATP phosphoribosyltransferase; PFAM: ATP phosphoribosyltransferase, catalytic domain; PRIAM: ATP phosphoribosyltransferase; SPTR: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase, catalytic domain; IMG reference gene:2504586610; PFAM: ATP phosphoribosyltransferase; TIGRFAM: ATP phosphoribosyltransferase YP_004413550.1 COGs: COG0141 Histidinol dehydrogenase; InterPro IPR012131; KEGG: afn:Acfer_0917 histidinol dehydrogenase; PFAM: Histidinol dehydrogenase, prokaryotic-type; PRIAM: Histidinol dehydrogenase; SPTR: Histidinol dehydrogenase; TIGRFAM: Histidinol dehydrogenase, prokaryotic-type; IMG reference gene:2504586611; PFAM: Histidinol dehydrogenase; TIGRFAM: histidinol dehydrogenase YP_004413551.1 COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807; KEGG: cth:Cthe_2884 imidazoleglycerol-phosphate dehydratase; PFAM: Imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase; IMG reference gene:2504586612; PFAM: Imidazoleglycerol-phosphate dehydratase YP_004413552.1 COGs: COG0118 Glutamine amidotransferase; InterPro IPR000991:IPR010139; KEGG: rxy:Rxyl_1104 imidazole glycerol phosphate synthase subunit HisH; PFAM: Glutamine amidotransferase class-I, C-terminal; SPTR: Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; TIGRFAM: Imidazole glycerol phosphate synthase, subunit H; IMG reference gene:2504586613; PFAM: Glutamine amidotransferase class-I; TIGRFAM: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit YP_004413553.1 COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062:IPR006063; KEGG: dae:Dtox_0756 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA; IMG reference gene:2504586614; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase YP_004413554.1 COGs: COG0107 Imidazoleglycerol-phosphate synthase; InterPro IPR004651:IPR006062; KEGG: adg:Adeg_0317 imidazole glycerol phosphate synthase subunit HisF; PFAM: Histidine biosynthesis; PRIAM:1-(5-phosphoribosyl)-5-((5-phosphoribosylamin o)methylideneamino)imidazole-4-carboxamideisomerase; SPTR: Imidazole glycerol phosphate synthase subunit hisF; TIGRFAM: Histidine biosynthesis, HisF; IMG reference gene:2504586615; PFAM: Histidine biosynthesis protein; TIGRFAM: imidazoleglycerol phosphate synthase, cyclase subunit YP_004413555.1 COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR008179:IPR002496:IPR021130; KEGG: ipo:Ilyop_2707 phosphoribosyl-AMP cyclohydrolase ;phosphoribosyl-ATP pyrophosphatase; PFAM: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; PRIAM: Phosphoribosyl-AMP cyclohydrolase., Phosphoribosyl-ATP diphosphatase; SPTR: Histidine biosynthesis protein HisIE; TIGRFAM: Phosphoribosyl-ATP pyrophosphohydrolase; IMG reference gene:2504586616; PFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase YP_004413556.1 InterPro IPR000415:IPR020051; KEGG: mpl:Mpal_0441 nitroreductase; PFAM: Nitroreductase-like; SPTR: NADH oxidase; TIGRFAM: SagB-type dehydrogenase domain; IMG reference gene:2504586617; PFAM: Nitroreductase family; TIGRFAM: SagB-type dehydrogenase domain YP_004413557.1 COGs: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; InterPro IPR000644:IPR010766:IPR004097; KEGG: dhd:Dhaf_1515 putative manganese-dependent inorganic pyrophosphatase; PFAM: DHHA2; Cystathionine beta-synthase, core; DRTGG; PRIAM: Inorganic diphosphatase; SMART: Cystathionine beta-synthase, core; SPTR: Putative manganese-dependent inorganic pyrophosphatase; IMG reference gene:2504586618; PFAM: DHH family; DRTGG domain; DHHA2 domain; CBS domain YP_004413558.1 COGs: COG0210 Superfamily I DNA and RNA helicase; InterPro IPR005751:IPR000212; KEGG: vpr:Vpar_1000 ATP-dependent DNA helicase PcrA; PFAM: DNA helicase, UvrD/REP type; SPTR: ATP-dependent DNA helicase PcrA; TIGRFAM: DNA helicase, ATP-dependent, PcrA type; IMG reference gene:2504586619; PFAM: UvrD/REP helicase; TIGRFAM: ATP-dependent DNA helicase PcrA YP_004413559.1 COGs: COG0272 NAD-dependent DNA ligase (contains BRCT domain type II); InterProIPR003583:IPR013839:IPR013840:IPR004149:IPR 001357:IPR001679:IPR004150; KEGG: clj:CLJU_c36970 DNA ligase; PFAM: NAD-dependent DNA ligase, adenylation; Zinc-finger, NAD-dependent DNA ligase C4-type; BRCT; NAD-dependent DNA ligase, OB-fold; PRIAM: DNA ligase (NAD(+)); SMART: NAD-dependent DNA ligase, N-terminal; Helix-hairpin-helix DNA-binding motif, class 1; BRCT; SPTR: DNA ligase, NAD-dependent; TIGRFAM: NAD-dependent DNA ligase; IMG reference gene:2504586620; PFAM: NAD-dependent DNA ligase OB-fold domain; NAD-dependent DNA ligase adenylation domain; NAD-dependent DNA ligase C4 zinc finger domain; BRCA1 C Terminus (BRCT) domain; TIGRFAM: DNA ligase, NAD-dependent YP_004413560.1 COGs: COG0037 ATPase of the PP-loop superfamily protein implicated in cell cycle control; InterPro IPR011063; KEGG: tjr:TherJR_2388 PP-loop domain protein; PFAM: tRNA(Ile)-lysidine/2-thiocytidine synthase; SPTR: ExsB family protein; IMG reference gene:2504586621; PFAM: PP-loop family YP_004413561.1 COGs: COG0602 Organic radical activating protein; InterPro IPR007197; KEGG: drm:Dred_1757 radical SAM domain-containing protein; PFAM: Radical SAM; SPTR: Radical SAM domain protein; IMG reference gene:2504586622; PFAM: Radical SAM superfamily YP_004413562.1 COGs: COG0720 6-pyruvoyl-tetrahydropterin synthase; InterPro IPR007115; KEGG: drm:Dred_1754 putative 6-pyruvoyl tetrahydropterin synthase; PFAM: 6-pyruvoyl tetrahydropterin synthase-related; SPTR: Queuosine biosynthesis protein QueD; TIGRFAM: queuosine biosynthesis protein QueD; IMG reference gene:2504586623; PFAM: 6-pyruvoyl tetrahydropterin synthase; TIGRFAM: queuosine biosynthesis protein QueD; 6-pyruvoyl tetrahydropterin synthase/QueD family protein YP_004413563.1 COGs: COG1215 Glycosyltransferase probably involved in cell wall biogenesis; InterPro IPR001173; KEGG: afn:Acfer_0771 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504586624; PFAM: Glycosyl transferase family 2 YP_004413564.1 COGs: COG1183 Phosphatidylserine synthase; InterPro IPR004533:IPR000462; KEGG: afn:Acfer_0770 CDP-diacylglycerol/serineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol--serine O-phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; IMG reference gene:2504586625; PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase YP_004413565.1 COGs: COG0688 Phosphatidylserine decarboxylase; HAMAP: Phosphatidylserine decarboxylase-related protein; InterPro IPR004428:IPR003817; KEGG: vpr:Vpar_1052 phosphatidylserine decarboxylase related protein; PFAM: Phosphatidylserine decarboxylase-related; PRIAM: Phosphatidylserine decarboxylase; SPTR: Phosphatidylserine decarboxylase proenzyme; TIGRFAM: Phosphatidylserine decarboxylase-related protein; IMG reference gene:2504586626; PFAM: Phosphatidylserine decarboxylase; TIGRFAM: phosphatidylserine decarboxylase precursor-related protein YP_004413566.1 COGs: COG1922 Teichoic acid biosynthesis protein; InterPro IPR004629; KEGG: afn:Acfer_0768 glycosyl transferase, WecB/TagA/CpsF family; PFAM: Glycosyl transferase WecB/TagA/CpsF; PRIAM: N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase; SPTR: Glycosyl transferase, WecB/TagA/CpsF family; TIGRFAM: Glycosyl transferase WecB/TagA/CpsF; IMG reference gene:2504586627; PFAM: Glycosyl transferase WecB/TagA/CpsF family; TIGRFAM: bacterial polymer biosynthesis proteins, WecB/TagA/CpsF family YP_004413567.1 COGs: COG0196 FAD synthase; InterPro IPR004821:IPR015864:IPR002606:IPR015865; KEGG: pth:PTH_1273 FAD synthase; PFAM: Riboflavin kinase; FAD synthetase; PRIAM: FAD synthetase., Riboflavin kinase; SMART: Riboflavin kinase; SPTR: Riboflavin biosynthesis protein RibF; TIGRFAM: Riboflavin kinase/FAD synthetase; Cytidyltransferase-related; IMG reference gene:2504586628; PFAM: Riboflavin kinase; FAD synthetase; TIGRFAM: riboflavin kinase/FMN adenylyltransferase; cytidyltransferase-related domain YP_004413568.1 COGs: COG0130 Pseudouridine synthase; InterPro IPR014780:IPR002501; KEGG: tte:TTE1390 tRNA pseudouridine synthase B; PFAM: Pseudouridine synthase II; SPTR: tRNA pseudouridine synthase B; TIGRFAM: tRNA pseudouridine synthase II, TruB; IMG reference gene:2504586629; PFAM: TruB family pseudouridylate synthase (N terminal domain); TIGRFAM: tRNA pseudouridine 55 synthase YP_004413569.1 COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR003156:IPR001667; KEGG: afn:Acfer_1354 phosphoesterase RecJ domain protein; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: Exopolyphosphatase family protein; IMG reference gene:2504586630; PFAM: DHH family; DHHA1 domain YP_004413570.1 COGs: COG0858 Ribosome-binding factor A; HAMAP: Ribosome-binding factor A; InterPro IPR000238; KEGG: bpf:BpOF4_19720 ribosome-binding factor A; PFAM: Ribosome-binding factor A; SPTR: Ribosome-binding factor A; TIGRFAM: Ribosome-binding factor A; IMG reference gene:2504586631; PFAM: Ribosome-binding factor A; TIGRFAM: ribosome-binding factor A YP_004413571.1 COGs: COG0532 Translation initiation factor 2 (IF-2; GTPase); InterProIPR000178:IPR005225:IPR006847:IPR000795:IPR 004161; KEGG: afn:Acfer_1356 translation initiation factor IF-2; PFAM: Protein synthesis factor, GTP-binding; Translation initiation factor IF-2, N-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Translation initiation factor IF-2; TIGRFAM: Translation initiation factor aIF-2, bacterial-like; Small GTP-binding protein; IMG reference gene:2504586632; PFAM: Elongation factor Tu domain 2; Translation-initiation factor 2; Translation initiation factor IF-2, N-terminal region; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation initiation factor IF-2 YP_004413572.1 COGs: COG2740 nucleic-acid-binding protein implicated in transcription termination; InterPro IPR007393; KEGG: cth:Cthe_0993 hypothetical protein; PFAM: Protein of unknown function DUF448; SPTR: Ribosomal protein L7Ae family protein; IMG reference gene:2504586633; PFAM: Protein of unknown function (DUF448) YP_004413573.1 COGs: COG0195 Transcription elongation factor; InterProIPR010213:IPR013735:IPR003029:IPR018111:IPR 022967:IPR004087; KEGG: tjr:TherJR_1374 transcription termination factor NusA; PFAM: Transcription factor NusA, N-terminal; Ribosomal protein S1, RNA-binding domain; K Homology, type 1, subgroup; SMART: RNA-binding domain, S1; K Homology; SPTR: Transcription termination factor NusA; TIGRFAM: Transcription termination factor NusA; IMG reference gene:2504586634; PFAM: NusA N-terminal domain; S1 RNA binding domain; TIGRFAM: transcription termination factor NusA YP_004413574.1 HAMAP: Ribosome maturation factor RimP; InterPro IPR003728; KEGG: vpr:Vpar_0782 protein of unknown function DUF150; PFAM: Ribosome maturation factor RimP; SPTR: Ribosome maturation factor rimP; IMG reference gene:2504586635; PFAM: Uncharacterised BCR, YhbC family COG0779 YP_004413575.1 COGs: COG0812 UDP-N-acetylmuramate dehydrogenase; InterPro IPR003170:IPR011601:IPR006094; KEGG: vpr:Vpar_1326 UDP-N-acetylenolpyruvoylglucosamine reductase; PFAM: UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: UDP-N-acetylmuramate dehydrogenase; SPTR: UDP-N-acetylenolpyruvoylglucosamine reductase; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase; IMG reference gene:2504586636; PFAM: FAD binding domain; UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; TIGRFAM: UDP-N-acetylenolpyruvoylglucosamine reductase YP_004413576.1 COGs: COG0219 rRNA methylase (SpoU class); InterPro IPR001537; KEGG: hor:Hore_11010 RNA methyltransferase, TrmH family, group 2; PFAM: tRNA/rRNA methyltransferase, SpoU; SPTR: RNA methyltransferase, TrmH family; IMG reference gene:2504586637; PFAM: SpoU rRNA Methylase family; TIGRFAM: rRNA methylase, putative, group 2 YP_004413577.1 COGs: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; HAMAP: Dihydroxy-acid dehydratase; InterPro IPR004404:IPR000581; KEGG: afn:Acfer_1425 dihydroxy-acid dehydratase; PFAM: Dihydroxy-acid/6-phosphogluconate dehydratase; PRIAM: Dihydroxy-acid dehydratase; SPTR: Dihydroxy-acid dehydratase; TIGRFAM: Dihydroxy-acid dehydratase; IMG reference gene:2504586638; PFAM: Dehydratase family; TIGRFAM: dihydroxy-acid dehydratase YP_004413578.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: chy:CHY_2619 cob(I)alamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; PRIAM: Cob(I)yrinic acid a,c-diamide adenosyltransferase; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; IMG reference gene:2504586639; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004413579.1 InterPro IPR001087; KEGG: afn:Acfer_0991 lipolytic protein G-D-S-L family; PFAM: Lipase, GDSL; SPTR: Putative uncharacterized protein; IMG reference gene:2504586640; PFAM: GDSL-like Lipase/Acylhydrolase YP_004413580.1 KEGG: mpd:MCP_1604 hypothetical protein; SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504586641 YP_004413581.1 COGs: COG1674 DNA segregation ATPase FtsK/SpoIIIE and related protein; InterPro IPR002543:IPR018541:IPR003593; KEGG: vpr:Vpar_1205 cell divisionFtsK/SpoIIIE; PFAM: Cell divisionFtsK/SpoIIIE; DNA translocase FtsK gamma; SMART: DNA translocase FtsK gamma; ATPase, AAA+ type, core; SPTR: Cell division FtsK/SpoIIIE; IMG reference gene:2504586642; PFAM: Ftsk gamma domain; FtsK/SpoIIIE family YP_004413582.1 COGs: COG0402 Cytosine deaminase and related metal-dependent hydrolase; InterPro IPR006680; KEGG: afn:Acfer_1329 amidohydrolase; PFAM: Amidohydrolase 1; PRIAM: S-adenosylhomocysteine deaminase; SPTR: Chlorohydrolase family protein; IMG reference gene:2504586643; PFAM: Amidohydrolase family YP_004413583.1 COGs: COG0499 S-adenosylhomocysteine hydrolase; InterPro IPR000043:IPR015878; KEGG: tjr:TherJR_2058 adenosylhomocysteinase; PFAM: Adenosylhomocysteinase; S-adenosyl-L-homocysteine hydrolase, NAD binding; PRIAM: Adenosylhomocysteinase; SPTR: Adenosylhomocysteinase; TIGRFAM: Adenosylhomocysteinase; IMG reference gene:2504586644; PFAM: S-adenosyl-L-homocysteine hydrolase, NAD binding domain; S-adenosyl-L-homocysteine hydrolase; TIGRFAM: adenosylhomocysteinase YP_004413584.1 COGs: COG0496 acid phosphatase; HAMAP: Survival protein SurE-like phosphatase/nucleotidase; InterPro IPR002828; KEGG: toc:Toce_1169 5'-nucleotidase ;exopolyphosphatase ;3'-nucleotidase; PFAM: Survival protein SurE-like phosphatase/nucleotidase; SPTR: 5'-nucleotidase surE; TIGRFAM: Survival protein SurE-like phosphatase/nucleotidase; IMG reference gene:2504586645; PFAM: Survival protein SurE; TIGRFAM: 5'/3'-nucleotidase SurE YP_004413585.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR000089; KEGG: oca:OCAR_5230 secretion protein HlyD family protein; PFAM: Biotin/lipoyl attachment; SPTR: Putative uncharacterized protein; IMG reference gene:2504586646 YP_004413586.1 COGs: COG0013 Alanyl-tRNA synthetase; InterPro IPR002318:IPR018164:IPR012947:IPR003156; KEGG: vpr:Vpar_1181 alanyl-tRNA synthetase; PFAM: Alanyl-tRNA synthetase, class IIc, N-terminal; Threonyl/alanyl tRNA synthetase, SAD; Phosphoesterase, DHHA1; SMART: Threonyl/alanyl tRNA synthetase, SAD; SPTR: Alanine--tRNA ligase; TIGRFAM: Alanyl-tRNA synthetase, class IIc; IMG reference gene:2504586647; PFAM: DHHA1 domain; Threonyl and Alanyl tRNA synthetase second additional domain; tRNA synthetases class II (A); TIGRFAM: alanine--tRNA ligase YP_004413587.1 KEGG: eck:EC55989_1691 putative tail fiber protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586648 YP_004413588.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: vpr:Vpar_0474 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase family protein; IMG reference gene:2504586649; PFAM: Polysaccharide deacetylase YP_004413589.1 COGs: COG0682 Prolipoprotein diacylglyceryltransferase; InterPro IPR001640; KEGG: vpr:Vpar_0966 prolipoprotein diacylglyceryl transferase; PFAM: Prolipoprotein diacylglyceryl transferase; SPTR: Prolipoprotein diacylglyceryl transferase; TIGRFAM: Prolipoprotein diacylglyceryl transferase; IMG reference gene:2504586650; PFAM: Prolipoprotein diacylglyceryl transferase; TIGRFAM: prolipoprotein diacylglyceryl transferase YP_004413590.1 COGs: COG0648 Endonuclease IV; InterPro IPR001719:IPR012307; KEGG: shi:Shel_21620 apurinic endonuclease APN1; PFAM: Xylose isomerase, TIM barrel domain; PRIAM: Deoxyribonuclease IV (phage-T(4)-induced); SMART: Endodeoxyribonuclease IV; SPTR: Probable endonuclease 4; TIGRFAM: Endodeoxyribonuclease IV; IMG reference gene:2504586651; PFAM: Xylose isomerase-like TIM barrel; TIGRFAM: apurinic endonuclease (APN1) YP_004413591.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: vpr:Vpar_0306 UspA domain protein; PFAM: UspA; SPTR: Universal stress family protein; IMG reference gene:2504586652; PFAM: Universal stress protein family YP_004413592.1 COGs: COG2327 conserved hypothetical protein; InterPro IPR019896:IPR007345; KEGG: drm:Dred_3108 polysaccharide pyruvyl transferase; PFAM: Polysaccharide pyruvyl transferase; SPTR: Polysaccharide pyruvyl transferase CsaB; TIGRFAM: Polysaccharide pyruvyl transferase, CsaB; IMG reference gene:2504586653; PFAM: Polysaccharide pyruvyl transferase; TIGRFAM: polysaccharide pyruvyl transferase CsaB YP_004413593.1 KEGG: vpr:Vpar_0803 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586654 YP_004413594.1 KEGG: aar:Acear_0278 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586655; PFAM: Protein of unknown function (DUF2993) YP_004413595.1 KEGG: bpm:BURPS1710b_3602 hypothetical protein; SPTR: Peptide chain release factor 2; manually curated; IMG reference gene:2504586656; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 2 YP_004413596.1 COGs: COG0653 Preprotein translocase subunit SecA (ATPase RNA helicase); HAMAP: SecA protein; InterProIPR000185:IPR011115:IPR011130:IPR011116:IPR 004027; KEGG: afn:Acfer_0653 preprotein translocase, SecA subunit; PFAM: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; SecA Wing/Scaffold; SEC-C motif; SMART: SecA DEAD-like, N-terminal; SecA preprotein, cross-linking domain; SPTR: Protein translocase subunit secA; TIGRFAM: SecA protein; IMG reference gene:2504586657; PFAM: SecA DEAD-like domain; SecA preprotein cross-linking domain; SEC-C motif; SecA Wing and Scaffold domain; TIGRFAM: preprotein translocase, SecA subunit YP_004413597.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR019264:IPR003740; KEGG: afn:Acfer_1451 protein of unknown function DUF2179; PFAM: Domain of unknown function DUF2179; Protein of unknown function DUF161; SPTR: YitT family protein; IMG reference gene:2504586658; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004413598.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586659 YP_004413599.1 COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR005790:IPR010372; KEGG: afn:Acfer_1453 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit; IMG reference gene:2504586660; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit YP_004413600.1 COGs: COG1052 Lactate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: cbe:Cbei_4594 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Glycerate dehydrogenase; IMG reference gene:2504586661; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004413601.1 InterPro IPR000620; KEGG: cbe:Cbei_3410 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Transporter, EamA family; IMG reference gene:2504586662; PFAM: EamA-like transporter family YP_004413602.1 COGs: COG0021 Transketolase; InterPro IPR005478:IPR005476:IPR005475:IPR005474; KEGG: csh:Closa_0072 transketolase; PFAM: Transketolase, N-terminal; Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: Formaldehyde transketolase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase; TIGRFAM: Transketolase, bacterial-like; IMG reference gene:2504586663; PFAM: Transketolase, thiamine diphosphate binding domain; Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain; TIGRFAM: transketolase, bacterial and yeast YP_004413603.1 COGs: COG1448 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: afn:Acfer_0480 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; SPTR: Aspartate/aromatic aminotransferase; IMG reference gene:2504586664; PFAM: Aminotransferase class I and II YP_004413604.1 COGs: COG0527 Aspartokinase; InterPro IPR001341:IPR001048:IPR002912:IPR005260; KEGG: vpr:Vpar_1126 aspartate kinase; PFAM: Aspartate/glutamate/uridylate kinase; Amino acid-binding ACT; SPTR: Aspartokinase; TIGRFAM: Aspartate kinase domain; Aspartate kinase, monofunctional class; IMG reference gene:2504586665; PFAM: ACT domain; Amino acid kinase family; TIGRFAM: aspartate kinase, monofunctional class; aspartate kinase YP_004413605.1 COGs: COG0564 Pseudouridylate synthase 23S RNA-specific; InterPro IPR006225:IPR006145; KEGG: drm:Dred_1348 RluA family pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RluC/RluD; IMG reference gene:2504586666; PFAM: RNA pseudouridylate synthase; TIGRFAM: pseudouridine synthase, RluA family YP_004413606.1 COGs: COG0191 Fructose/tagatose bisphosphate aldolase; InterPro IPR000771:IPR011289; KEGG: cce:Ccel_2222 fructose-1,6-bisphosphate aldolase, class II; PFAM: Ketose-bisphosphate aldolase, class-II; PRIAM: Fructose-bisphosphate aldolase; SPTR: Fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: Fructose-1,6-bisphosphate aldolase, class 2; Ketose-bisphosphate aldolase, class-II; IMG reference gene:2504586667; PFAM: Fructose-bisphosphate aldolase class-II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II, various bacterial and amitochondriate protist YP_004413607.1 COGs: COG3588 Fructose-1 6-bisphosphate aldolase; InterPro IPR000741; KEGG: fjo:Fjoh_0953 fructose-1,6-bisphosphate aldolase; PFAM: Fructose-bisphosphate aldolase, class-I; SPTR: Fructose-bisphosphate aldolase class-I; IMG reference gene:2504586668; PFAM: Fructose-bisphosphate aldolase class-I YP_004413608.1 SPTR: Putative cell division protein ZipA; IMG reference gene:2504586669 YP_004413609.1 InterPro IPR011733; KEGG: tde:TDE0907 hypothetical protein; PFAM: Conserved hypothetical CHP02185, integral membrane; SPTR: Putative membrane protein; TIGRFAM: Conserved hypothetical CHP02185, integral membrane; IMG reference gene:2504586670; PFAM: Hypothetical bacterial integral membrane protein (Trep_Strep); TIGRFAM: conserved hypothetical integral membrane protein TIGR02185 YP_004413610.1 COGs: COG1123 ATPase components of various ABC-type transport systems contain duplicated ATPase; InterPro IPR003593:IPR003439; KEGG: tde:TDE0906 ABC transporter, ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504586671; PFAM: ABC transporter YP_004413611.1 InterPro IPR003339; KEGG: tde:TDE0905 hypothetical protein; PFAM: Cobalt transport protein; SPTR: Putative membrane protein; IMG reference gene:2504586672; PFAM: Cobalt transport protein YP_004413612.1 KEGG: tde:TDE0975 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586673 YP_004413613.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1343 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Putative TonB-dependent receptor plug domain protein; manually curated; IMG reference gene:2504586674; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004413614.1 COGs: COG1074 ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains); InterPro IPR014152:IPR000212; KEGG: tjr:TherJR_1006 recombination helicase AddA; PFAM: DNA helicase, UvrD/REP type; PRIAM: Exodeoxyribonuclease V; SPTR: ATP-dependent helicase/nuclease subunit A; TIGRFAM: DNA helicase subunit AddA; IMG reference gene:2504586675; PFAM: UvrD/REP helicase; TIGRFAM: helicase-exonuclease AddAB, AddA subunit, Firmicutes type YP_004413615.1 COGs: COG3857 ATP-dependent nuclease subunit B; InterPro IPR014140; KEGG: tjr:TherJR_1005 ATP-dependent nuclease subunit B; SPTR: ATP-dependent nuclease subunit B; TIGRFAM: DNA helicase subunit AddB; IMG reference gene:2504586676; TIGRFAM: helicase-exonuclease AddAB, AddB subunit YP_004413616.1 COGs: COG1541 Coenzyme F390 synthetase; KEGG: sfu:Sfum_4074 phenylacetate-CoA ligase; SPTR: Putative phenylacetate-coenzyme A ligase; IMG reference gene:2504586677 YP_004413617.1 COGs: COG1352 Methylase of chemotaxis methyl-accepting protein; InterPro IPR022641:IPR022642:IPR000780; KEGG: nth:Nther_1604 MCP methyltransferase, CheR-type; PFAM: MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal; MCP methyltransferase, CheR-type, all-alpha domain, N-terminal; PRIAM: Protein-glutamate O-methyltransferase; SMART: MCP methyltransferase, CheR-type; SPTR: CheR methyltransferase, SAM binding domain protein; IMG reference gene:2504586678; PFAM: CheR methyltransferase, SAM binding domain; CheR methyltransferase, all-alpha domain YP_004413618.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: has:Halsa_2169 heat shock protein HSP20; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein 16; IMG reference gene:2504586679; PFAM: Hsp20/alpha crystallin family YP_004413619.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: vpr:Vpar_0068 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: Hemin ABC transporter, permease protein; IMG reference gene:2504586680; PFAM: FecCD transport family YP_004413620.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003439:IPR003593; KEGG: afn:Acfer_0321 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Hemin import ATP-binding protein HmuV; IMG reference gene:2504586681; PFAM: ABC transporter YP_004413621.1 COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510; KEGG: dal:Dalk_0724 oxidoreductase/nitrogenase component 1; PFAM: Nitrogenase/oxidoreductase, component 1; SPTR: Putative nitrogenase associated protein E; IMG reference gene:2504586682; PFAM: Nitrogenase component 1 type Oxidoreductase YP_004413622.1 COGs: COG2710 Nitrogenase molybdenum-iron protein alpha and beta chains; InterPro IPR000510; KEGG: ckr:CKR_0741 hypothetical protein; PFAM: Nitrogenase/oxidoreductase, component 1; SPTR: Putative nitrogenase; IMG reference gene:2504586683; PFAM: Nitrogenase component 1 type Oxidoreductase YP_004413623.1 COGs: COG1348 Nitrogenase subunit NifH (ATPase); InterPro IPR000392; KEGG: clj:CLJU_c23530 nitrogenase iron protein; PFAM: Nitrogenase iron protein, subunit NifH/Protochlorophyllide reductase, subunit ChlL; PRIAM: Nitrogenase; SPTR: Nitrogenase iron protein; IMG reference gene:2504586684; PFAM: 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family; TIGRFAM: nitrogenase iron protein YP_004413624.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: afn:Acfer_0320 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504586685; PFAM: Periplasmic binding protein YP_004413625.1 COGs: COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatase; InterPro IPR003672; KEGG: vpr:Vpar_0072 CobN/magnesium chelatase; PFAM: CobN/magnesium chelatase; PRIAM: Cobaltochelatase; SPTR: Cobaltochelatase, CobN subunit; IMG reference gene:2504586686; PFAM: CobN/Magnesium Chelatase; TIGRFAM: magnesium chelatase, H subunit; cobaltochelatase, CobN subunit YP_004413626.1 COGs: COG1865 conserved hypothetical protein; InterPro IPR002808; KEGG: tjr:TherJR_1261 protein of unknown function DUF105; PFAM: Adenosylcobinamide amidohydrolase, CbiZ; SPTR: Putative adenosylcobinamide amidohydrolase; IMG reference gene:2504586687; PFAM: Adenosylcobinamide amidohydrolase YP_004413627.1 COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR002035; KEGG: dsy:DSY3869 hypothetical protein; PFAM: von Willebrand factor, type A; PRIAM: Magnesium chelatase; SMART: von Willebrand factor, type A; SPTR: Magnesium-chelatase, subunit D/I family; IMG reference gene:2504586688; PFAM: von Willebrand factor type A domain; AAA domain (dynein-related subfamily) YP_004413628.1 COGs: COG1239 Mg-chelatase subunit ChlI; InterPro IPR003593; KEGG: aoe:Clos_2327 magnesium chelatase; PRIAM: Magnesium chelatase; SMART: ATPase, AAA+ type, core; SPTR: Magnesium chelatase, ATPase subunit I; IMG reference gene:2504586689; PFAM: Magnesium chelatase, subunit ChlI YP_004413629.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: afn:Acfer_0320 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504586690; PFAM: Periplasmic binding protein YP_004413630.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197:IPR006638; KEGG: mtp:Mthe_0433 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative radical SAM; IMG reference gene:2504586691; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004413631.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: cce:Ccel_3204 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Putative periplasmic binding protein; IMG reference gene:2504586692; PFAM: Periplasmic binding protein YP_004413632.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_0065 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: TonB-dependent receptor; IMG reference gene:2504586693; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004413633.1 InterPro IPR007197:IPR006638; KEGG: dae:Dtox_0061 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504586694; PFAM: Radical SAM superfamily YP_004413634.1 COGs: COG0193 Peptidyl-tRNA hydrolase; InterPro IPR001328; KEGG: vpr:Vpar_0609 peptidyl-tRNA hydrolase; PFAM: Peptidyl-tRNA hydrolase; PRIAM: Aminoacyl-tRNA hydrolase; SPTR: Peptidyl-tRNA hydrolase; TIGRFAM: Peptidyl-tRNA hydrolase; IMG reference gene:2504586695; PFAM: Peptidyl-tRNA hydrolase; TIGRFAM: peptidyl-tRNA hydrolase YP_004413635.1 InterPro IPR010181; KEGG: eel:EUBELI_20402 hypothetical protein; PFAM: CGCAxxGCC motif; SPTR: Redox family protein; IMG reference gene:2504586696; PFAM: Putative redox-active protein (C_GCAxxG_C_C) YP_004413636.1 COGs: COG1194 A/G-specific DNA glycosylase; InterPro IPR003265:IPR000445:IPR005760:IPR003651; KEGG: csh:Closa_2490 A/G-specific adenine glycosylase; PFAM: HhH-GPD domain; Helix-hairpin-helix motif; SMART: HhH-GPD domain; Endonuclease III-like, iron-sulphur cluster loop motif; SPTR: A/G-specific adenine glycosylase; TIGRFAM: A/G-specific adenine glycosylase MutY, bacterial form; IMG reference gene:2504586697; PFAM: HhH-GPD superfamily base excision DNA repair protein; Helix-hairpin-helix motif; TIGRFAM: A/G-specific adenine glycosylase YP_004413637.1 COGs: COG1213 sugar nucleotidyltransferase; KEGG: hhe:HH0077 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586698; PFAM: Uncharacterized protein family UPF0007 YP_004413638.1 COGs: COG0560 Phosphoserine phosphatase; InterPro IPR006383:IPR005834; KEGG: dds:Ddes_1017 HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase-like hydrolase; SPTR: Phosphoserine phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IB, PSPase-like; IMG reference gene:2504586699; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Haloacid Dehalogenase superfamily, subfamily IB, phosphoserine phosphatase-like; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004413639.1 InterPro IPR001173; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase; IMG reference gene:2504586701; PFAM: Glycosyl transferase family 2 YP_004413640.1 COGs: COG0546 phosphatase; InterPro IPR006402:IPR005834; KEGG: dat:HRM2_44240 Gph2; PFAM: Haloacid dehalogenase-like hydrolase; PRIAM: Phosphoglycolate phosphatase; SPTR: Phosphoglycolate phosphatase; TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; IMG reference gene:2504586702; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED; haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E; 2-phosphoglycolate phosphatase, prokaryotic YP_004413641.1 COGs: COG2265 SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase; InterPro IPR001566:IPR002792:IPR013216:IPR010280; KEGG: afn:Acfer_1736 RNA methyltransferase, TrmA family; PFAM: Deoxyribonuclease/rho motif-related TRAM; Methyltransferase type 11; (Uracil-5)-methyltransferase; SPTR: 23S rRNA (Uracil-5-)-methyltransferase RumA; TIGRFAM: 23S rRNA methyltransferase/RumA; IMG reference gene:2504586703; PFAM: TRAM domain; tRNA (Uracil-5-)-methyltransferase; TIGRFAM: 23S rRNA (uracil-5-)-methyltransferase RumA YP_004413642.1 COGs: COG0064 Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog); InterPro IPR006075:IPR018027:IPR004413; KEGG: tjr:TherJR_0872 glutamyl-tRNA(Gln) amidotransferase, B subunit; PFAM: Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, N-terminal; Asn/Gln amidotransferase; SMART: Asn/Gln amidotransferase; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase, B subunit; IMG reference gene:2504586704; PFAM: GatB/GatE catalytic domain; GatB domain; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit YP_004413643.1 COGs: COG0154 Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidase; HAMAP: Glutamyl-tRNA(Gln) amidotransferase A subunit; InterPro IPR004412:IPR000120; KEGG: mta:Moth_2009 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A; PFAM: Amidase; PRIAM: Amidase; SPTR: Glutamyl-tRNA(Gln) amidotransferase subunit A; TIGRFAM: Glutamyl-tRNA(Gln) amidotransferase A subunit; IMG reference gene:2504586705; PFAM: Amidase; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit YP_004413644.1 COGs: COG0721 Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit; HAMAP: Glu-tRNAGln amidotransferase, C subunit; InterPro IPR003837; KEGG: gsu:GSU3383 glutamyl-tRNA(Gln) amidotransferase subunit C; PFAM: Glu-tRNAGln amidotransferase, C subunit; SPTR: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; TIGRFAM: Glu-tRNAGln amidotransferase, C subunit; IMG reference gene:2504586706; PFAM: Glu-tRNAGln amidotransferase C subunit; TIGRFAM: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit YP_004413645.1 COGs: COG0028 Thiamine pyrophosphate-requiring protein; InterPro IPR012846:IPR011766:IPR012001:IPR012000; KEGG: thx:Thet_0020 acetolactate synthase large subunit, biosynthetic type; PFAM: Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Thiamine pyrophosphate enzyme, central domain; PRIAM: Acetolactate synthase; SPTR: Acetolactate synthase, large subunit; TIGRFAM: Acetolactate synthase, large subunit, biosynthetic; IMG reference gene:2504586707; PFAM: Thiamine pyrophosphate enzyme, central domain; Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type YP_004413646.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR004429:IPR001804; KEGG: afn:Acfer_0154 3-isopropylmalate dehydrogenase; PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: 3-isopropylmalate dehydrogenase; SPTR: 3-isopropylmalate dehydrogenase; TIGRFAM: Isopropylmalate dehydrogenase; IMG reference gene:2504586708; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: 3-isopropylmalate dehydrogenase YP_004413647.1 COGs: COG0066 3-isopropylmalate dehydratase small subunit; InterPro IPR000573:IPR011827; KEGG: dth:DICTH_1065 3-isopropylmalate dehydratase, small subunit; PFAM: Aconitase A/isopropylmalate dehydratase small subunit, swivel; PRIAM: (R)-2-methylmalate dehydratase; SPTR: 3-isopropylmalate dehydratase, small subunit; TIGRFAM: 3-isopropylmalate dehydratase, small subunit, subgroup; IMG reference gene:2504586709; PFAM: Aconitase C-terminal domain; TIGRFAM: 3-isopropylmalate dehydratase, small subunit YP_004413648.1 COGs: COG0065 3-isopropylmalate dehydratase large subunit; InterPro IPR006251:IPR011826:IPR011823:IPR001030; KEGG: vpr:Vpar_0095 3-isopropylmalate dehydratase, large subunit; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; SPTR: 3-isopropylmalate dehydratase large subunit; TIGRFAM: Homoaconitase/3-isopropylmalate dehydratase, large subunit, subgroup; Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic; 3-isopropylmalate dehydratase, large subunit, prokaryotic; IMG reference gene:2504586710; PFAM: Aconitase family (aconitate hydratase); TIGRFAM: 3-isopropylmalate dehydratase, large subunit; homoaconitate hydratase family protein YP_004413649.1 COGs: COG0059 Ketol-acid reductoisomerase; InterPro IPR013023:IPR013116:IPR000506; KEGG: afn:Acfer_0158 ketol-acid reductoisomerase; PFAM: Acetohydroxy acid isomeroreductase, catalytic; Acetohydroxy acid isomeroreductase C-terminal; PRIAM: Ketol-acid reductoisomerase; SPTR: Ketol-acid reductoisomerase; TIGRFAM: Acetohydroxy acid isomeroreductase; IMG reference gene:2504586711; PFAM: Acetohydroxy acid isomeroreductase, catalytic domain; TIGRFAM: ketol-acid reductoisomerase YP_004413650.1 COGs: COG0440 Acetolactate synthase small (regulatory) subunit; InterPro IPR002912:IPR004789:IPR019455; KEGG: ate:Athe_0503 acetolactate synthase small subunit; PFAM: Acetolactate synthase, small subunit, C-terminal; Amino acid-binding ACT; SPTR: Acetolactate synthase, small subunit; TIGRFAM: Acetolactate synthase, small subunit; IMG reference gene:2504586712; PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit YP_004413651.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR004540:IPR005517:IPR005225:IPR000795:IPR 004161:IPR000640; KEGG: afn:Acfer_0459 translation elongation factor G; PFAM: Translation elongation factor EFG/EF2, domain IV; Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Translation elongation factor G; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; IMG reference gene:2504586713; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004413652.1 COGs: COG2096 conserved hypothetical protein; InterPro IPR017858:IPR002779; KEGG: vpr:Vpar_0903 ATP/cobalamin adenosyltransferase; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, EutT/PduO type; SPTR: ATP:cob(I)alamin adenosyltransferase; TIGRFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase, PduO-type, N-terminal; IMG reference gene:2504586714; PFAM: Cobalamin adenosyltransferase; TIGRFAM: ATP:cob(I)alamin adenosyltransferase YP_004413653.1 COGs: COG0105 Nucleoside diphosphate kinase; HAMAP: Nucleoside diphosphate kinase; InterPro IPR001564; KEGG: sde:Sde_1430 nucleoside diphosphate kinase; PFAM: Nucleoside diphosphate kinase; PRIAM: Nucleoside-diphosphate kinase; SMART: Nucleoside diphosphate kinase; SPTR: Nucleoside diphosphate kinase; IMG reference gene:2504586715; PFAM: Nucleoside diphosphate kinase YP_004413654.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: tmt:Tmath_1072 carbonic anhydrase; SPTR: Transferase hexapeptide repeat family protein; IMG reference gene:2504586716 YP_004413655.1 COGs: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; InterPro IPR003607:IPR006674:IPR002646; KEGG: tcx:Tcr_0240 metal dependent phosphohydrolase; PFAM: Poly A polymerase, head domain; Metal-dependent phosphohydrolase, HD subdomain; PRIAM: tRNA adenylyltransferase; SPTR: tRNA nucleotidyltransferase; IMG reference gene:2504586717; PFAM: HD domain; Poly A polymerase head domain YP_004413656.1 COGs: COG0083 Homoserine kinase; InterPro IPR013750:IPR006204:IPR000870; KEGG: hmo:HM1_1938 homoserine kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; SPTR: Homoserine kinase; TIGRFAM: Homoserine kinase; IMG reference gene:2504586718; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: homoserine kinase YP_004413657.1 COGs: COG0460 Homoserine dehydrogenase; InterPro IPR001342:IPR005106:IPR002912; KEGG: drm:Dred_1165 homoserine dehydrogenase; PFAM: Homoserine dehydrogenase, catalytic; Aspartate/homoserine dehydrogenase, NAD-binding; Amino acid-binding ACT; SPTR: Homoserine dehydrogenase; IMG reference gene:2504586719; PFAM: Homoserine dehydrogenase; Homoserine dehydrogenase, NAD binding domain; ACT domain YP_004413658.1 COGs: COG4492 ACT domain-containing protein; KEGG: afn:Acfer_1234 amino acid-binding ACT domain protein; SPTR: ACT domain-containing protein PheB; IMG reference gene:2504586720 YP_004413659.1 COGs: COG0344 membrane protein; InterPro IPR003811; KEGG: aar:Acear_1046 acyl-phosphate glycerol-3-phosphate acyltransferase; PFAM: Glycerol-3-phosphate acyltransferase, bacteria; SPTR: Glycerol-3-phosphate acyltransferase; TIGRFAM: Glycerol-3-phosphate acyltransferase, bacteria; IMG reference gene:2504586721; PFAM: Domain of unknown function (DUF205); TIGRFAM: acyl-phosphate glycerol 3-phosphate acyltransferase YP_004413660.1 COGs: COG1160 GTPase; InterPro IPR003593:IPR002917:IPR005225:IPR016484; KEGG: tjr:TherJR_1582 ribosome-associated GTPase EngA; PFAM: GTP-binding protein, HSR1-related; SMART: ATPase, AAA+ type, core; SPTR: GTP-binding protein engA; TIGRFAM: GTP-binding, EngA; Small GTP-binding protein; IMG reference gene:2504586722; PFAM: GTPase of unknown function; TIGRFAM: ribosome-associated GTPase EngA; small GTP-binding protein domain YP_004413661.1 COGs: COG1625 Fe-S oxidoreductase related to NifB/MoaA family; InterPro IPR001478:IPR007549; KEGG: dau:Daud_1173 hypothetical protein; PFAM: Domain of unknown function DUF512; PDZ/DHR/GLGF; SPTR: PDZ domain protein; IMG reference gene:2504586723; PFAM: PDZ domain (Also known as DHR or GLGF); Protein of unknown function (DUF512); TIGRFAM: putative FeS-containing Cyanobacterial-specific oxidoreductase YP_004413662.1 COGs: COG0539 Ribosomal protein S1; InterPro IPR003029:IPR022967; KEGG: amt:Amet_2624 RNA-binding S1 domain-containing protein; PFAM: Ribosomal protein S1, RNA-binding domain; SMART: RNA-binding domain, S1; SPTR: Hydroxymethylbutenyl pyrophosphate reductase; IMG reference gene:2504586724; PFAM: S1 RNA binding domain; TIGRFAM: ribosomal protein S1 YP_004413663.1 COGs: COG0761 Penicillin tolerance protein; InterPro IPR003451; KEGG: vpr:Vpar_0831 hydroxymethylbutenyl pyrophosphate reductase; PFAM: LytB protein; PRIAM: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; SPTR: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; TIGRFAM: LytB protein; IMG reference gene:2504586725; PFAM: LytB protein; TIGRFAM: (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate reductase (IPP and DMAPP forming) YP_004413664.1 COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: afn:Acfer_1240 1-acyl-sn-glycerol-3-phosphate acyltransferase; PFAM: Phospholipid/glycerol acyltransferase; SMART: Phospholipid/glycerol acyltransferase; SPTR: 1-acyl-sn-glycerol-3-phosphate acyltransferase; IMG reference gene:2504586726; PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases YP_004413665.1 COGs: COG0283 Cytidylate kinase; HAMAP: Cytidylate kinase; InterPro IPR003136:IPR000623:IPR011994; KEGG: sth:STH1668 cytidylate kinase; PFAM: Cytidylate kinase domain; Shikimate kinase; SPTR: Cytidylate kinase; TIGRFAM: Cytidylate kinase; IMG reference gene:2504586727; PFAM: Cytidylate kinase; Rad17 cell cycle checkpoint protein; TIGRFAM: cytidylate kinase YP_004413666.1 COGs: COG0128 5-enolpyruvylshikimate-3-phosphate synthase; InterPro IPR001986:IPR006264; KEGG: dau:Daud_1181 3-phosphoshikimate 1-carboxyvinyltransferase; PFAM: Enolpyruvate transferase domain; PRIAM: 3-phosphoshikimate 1-carboxyvinyltransferase; SPTR: 3-phosphoshikimate 1-carboxyvinyltransferase; TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase; IMG reference gene:2504586728; PFAM: EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); TIGRFAM: 3-phosphoshikimate 1-carboxyvinyltransferase YP_004413667.1 COGs: COG2081 flavoprotein; InterPro IPR004792; KEGG: afn:Acfer_1242 HI0933 family protein; PFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; SPTR: Pyridine nucleotide-disulfide oxidoreductase; TIGRFAM: Conserved hypothetical protein CHP00275, flavoprotein HI0933-like; IMG reference gene:2504586729; PFAM: HI0933-like protein; TIGRFAM: flavoprotein, HI0933 family YP_004413668.1 COGs: COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthase; InterPro IPR002942:IPR006145:IPR000748; KEGG: drm:Dred_1142 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; SPTR: Pseudouridine synthase; TIGRFAM: Pseudouridine synthase, RsuA/RluB/E/F; IMG reference gene:2504586730; PFAM: RNA pseudouridylate synthase; S4 domain; TIGRFAM: pseudouridine synthase YP_004413669.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586731 YP_004413670.1 COGs: COG0587 DNA polymerase III alpha subunit; InterProIPR004013:IPR011708:IPR004365:IPR003141:IPR 004805; KEGG: dae:Dtox_0809 DNA polymerase III DnaE; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: DNA-directed DNA polymerase; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; TIGRFAM: DNA polymerase III, alpha subunit; IMG reference gene:2504586732; PFAM: Bacterial DNA polymerase III alpha subunit; PHP domain; OB-fold nucleic acid binding domain; TIGRFAM: DNA-directed DNA polymerase III (polc) YP_004413671.1 COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633; KEGG: ele:Elen_1281 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; SPTR: Putative sensory box sensor/GGDEF/EAL domain protein; tmRNA as predicted by Rfam (RF00023), score 184.64; IMG reference gene:2504586733; PFAM: EAL domain; GGDEF domain YP_004413672.1 COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: ere:EUBREC_1577 serine acetyltransferase, plasmid; PRIAM: Serine O-acetyltransferase; SPTR: Serine acetyltransferase; IMG reference gene:2504586734; TIGRFAM: serine O-acetyltransferase YP_004413673.1 COGs: COG4947 conserved hypothetical protein; InterPro IPR000801; KEGG: lba:Lebu_1199 putative esterase; PFAM: Putative esterase; SPTR: Putative esterase; IMG reference gene:2504586735; PFAM: Putative esterase YP_004413674.1 COGs: COG0239 Integral membrane protein possibly involved in chromosome condensation; InterPro IPR003691; KEGG: gbm:Gbem_0702 camphor resistance protein CrcB; PFAM: Camphor resistance CrcB protein; SPTR: Protein CrcB homolog; TIGRFAM: Camphor resistance CrcB protein; IMG reference gene:2504586736; PFAM: CrcB-like protein; TIGRFAM: crcB protein YP_004413675.1 COGs: COG2814 Arabinose efflux permease; InterPro IPR005828; KEGG: acd:AOLE_18385 major facilitator superfamily protein; PFAM: General substrate transporter; SPTR: Major facilitator family transporter; IMG reference gene:2504586737; PFAM: Sugar (and other) transporter; TIGRFAM: benzoate transport YP_004413676.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR005730:IPR022643; KEGG: bha:BH3958 carboxynorspermidine decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, C-terminal; SPTR: Carboxynorspermidine decarboxylase; TIGRFAM: Carboxynorspermidine decarboxylase; IMG reference gene:2504586738; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; TIGRFAM: carboxynorspermidine decarboxylase YP_004413677.1 COGs: COG1748 Saccharopine dehydrogenase and related protein; InterPro IPR005097; KEGG: bha:BH3957 hypothetical protein; PFAM: Saccharopine dehydrogenase / Homospermidine synthase; SPTR: Saccharopine dehydrogenase; IMG reference gene:2504586739; PFAM: Saccharopine dehydrogenase YP_004413678.1 COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035:IPR005925; KEGG: lba:Lebu_1823 agmatinase; PFAM: Ureohydrolase; PRIAM: Agmatinase; SPTR: Agmatinase; TIGRFAM: Putative agmatinase; IMG reference gene:2504586740; PFAM: Arginase family; TIGRFAM: agmatinase YP_004413679.1 COGs: COG0421 Spermidine synthase; InterPro IPR001045; KEGG: cpf:CPF_0529 spermidine synthase; PFAM: Spermine synthase; SPTR: Spermidine synthase; TIGRFAM: Spermine synthase; IMG reference gene:2504586741; PFAM: Spermine/spermidine synthase; TIGRFAM: spermidine synthase YP_004413680.1 COGs: COG1982 Arginine/lysine/ornithine decarboxylase; InterPro IPR000310:IPR008286; KEGG: afn:Acfer_1890 Orn/Lys/Arg decarboxylase major region; PFAM: Orn/Lys/Arg decarboxylase, major domain; Orn/Lys/Arg decarboxylase, C-terminal; PRIAM: Arginine decarboxylase; SPTR: Lysine decarboxylase; IMG reference gene:2504586742; PFAM: Orn/Lys/Arg decarboxylase, C-terminal domain; Orn/Lys/Arg decarboxylase, major domain YP_004413681.1 COGs: COG1586 S-adenosylmethionine decarboxylase; InterPro IPR003826:IPR009165; KEGG: cbe:Cbei_4412 S-adenosylmethionine decarboxylase; PFAM: S-adenosylmethionine decarboxylase, bacterial/archaeal; PRIAM: Adenosylmethionine decarboxylase; SPTR: S-adenosylmethionine decarboxylase proenzyme; TIGRFAM: S-adenosylmethionine decarboxylase, bacterial; IMG reference gene:2504586743; PFAM: S-adenosylmethionine decarboxylase; TIGRFAM: S-adenosylmethionine decarboxylase proenzyme, Escherichia coli form YP_004413682.1 InterPro IPR010106; KEGG: afn:Acfer_1259 tetracycline resistance leader peptide; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504586744; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413683.1 COGs: COG0326 Molecular chaperone HSP90 family; InterPro IPR020576:IPR003594; KEGG: aar:Acear_1255 heat shock protein HSP90; PFAM: Heat shock protein Hsp90, C-terminal; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Chaperone protein htpG; IMG reference gene:2504586745; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Hsp90 protein YP_004413684.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586746 YP_004413685.1 COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR008136; KEGG: adg:Adeg_0626 competence damage-inducible protein A; PFAM: CinA, C-terminal; SPTR: Competence/damage-inducible protein CinA; TIGRFAM: CinA, C-terminal; IMG reference gene:2504586747; PFAM: Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA C-terminal domain YP_004413686.1 COGs: COG0621 2-methylthioadenine synthetase; HAMAP: Ribosomal protein S12 methylthiotransferase RimO; InterProIPR005840:IPR013848:IPR007197:IPR006638:IPR 005839; KEGG: afn:Acfer_1017 MiaB-like tRNA modifying enzyme YliG; PFAM: Methylthiotransferase, N-terminal; Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: RNA modification enzyme, MiaB family; TIGRFAM: Ribosomal protein S12 methylthiotransferase RimO; Methylthiotransferase; IMG reference gene:2504586748; PFAM: Radical SAM superfamily; Uncharacterized protein family UPF0004; TIGRFAM: ribosomal protein S12 methylthiotransferase RimO; radical SAM methylthiotransferase, MiaB/RimO family YP_004413687.1 COGs: COG1840 ABC-type Fe3+ transport system periplasmic component; InterPro IPR006059; KEGG: vpr:Vpar_1202 extracellular solute-binding protein family 1; PFAM: Bacterial extracellular solute-binding, family 1; SPTR: Putative bacterial extracellular solute-binding protein; IMG reference gene:2504586749; PFAM: Bacterial extracellular solute-binding protein YP_004413688.1 COGs: COG1293 RNA-binding protein homologous to eukaryotic snRNP; InterPro IPR008616:IPR008532; KEGG: tit:Thit_1324 fibronectin-binding A domain protein; PFAM: Fibronectin-binding A, N-terminal; Domain of unknown function DUF814; SPTR: Fibronectin-binding protein; IMG reference gene:2504586750; PFAM: Domain of unknown function (DUF814); Fibronectin-binding protein A N-terminus (FbpA) YP_004413689.1 COGs: COG0756 dUTPase; InterPro IPR008180:IPR008181; KEGG: vpr:Vpar_0770 deoxyUTP pyrophosphatase; PFAM: DeoxyUTP pyrophosphatase domain; SPTR: DUTP diphosphatase; TIGRFAM: DeoxyUTP pyrophosphatase; IMG reference gene:2504586751; PFAM: dUTPase; TIGRFAM: deoxyuridine 5'-triphosphate nucleotidohydrolase (dut) YP_004413690.1 COGs: COG1923 Uncharacterized host factor I protein; HAMAP: Host factor Hfq; InterPro IPR005001:IPR001163; KEGG: chy:CHY_1393 hfq protein; PFAM: Like-Sm ribonucleoprotein (LSM) domain; SPTR: RNA chaperone Hfq; TIGRFAM: Host factor Hfq; IMG reference gene:2504586752; PFAM: LSM domain; TIGRFAM: RNA chaperone Hfq YP_004413691.1 COGs: COG0324 tRNA delta(2)-isopentenylpyrophosphate transferase; InterPro IPR018022:IPR002627; KEGG: bay:RBAM_017130 tRNA delta(2)-isopentenylpyrophosphate transferase; PFAM: tRNA isopentenyltransferase; PRIAM: tRNA isopentenyltransferase; SPTR: tRNA dimethylallyltransferase; TIGRFAM: tRNA delta(2)-isopentenylpyrophosphate transferase; IMG reference gene:2504586753; PFAM: IPP transferase; TIGRFAM: tRNA dimethylallyltransferase YP_004413692.1 COGs: COG2220 Zn-dependent hydrolase of the beta-lactamase fold; InterPro IPR001279; KEGG: afn:Acfer_1231 beta-lactamase domain protein; PFAM: Beta-lactamase-like; SMART: Beta-lactamase-like; SPTR: UPF0173 metal-dependent hydrolase SELSPUOL_00953; IMG reference gene:2504586754; PFAM: Metallo-beta-lactamase superfamily YP_004413693.1 COGs: COG1564 Thiamine pyrophosphokinase; InterPro IPR006282:IPR007371; KEGG: aco:Amico_0854 thiamine pyrophosphokinase; PFAM: Thiamin pyrophosphokinase, catalytic domain; SPTR: Thiamine diphosphokinase; TIGRFAM: Thiamin pyrophosphokinase; IMG reference gene:2504586755; PFAM: Thiamin pyrophosphokinase, vitamin B1 binding domain; Thiamin pyrophosphokinase, catalytic domain; TIGRFAM: thiamine pyrophosphokinase YP_004413694.1 COGs: COG0566 rRNA methylase; InterPro IPR013123:IPR001537; KEGG: dae:Dtox_2397 tRNA/rRNA methyltransferase (SpoU); PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; SMART: RNA 2-O ribose methyltransferase, substrate binding; SPTR: RNA methyltransferase, TrmH family; IMG reference gene:2504586756; PFAM: SpoU rRNA Methylase family; RNA 2'-O ribose methyltransferase substrate binding YP_004413695.1 COGs: COG0292 Ribosomal protein L20; InterPro IPR005813; KEGG: vpr:Vpar_1167 ribosomal protein L20; PFAM: Ribosomal protein L20; SPTR: 50S ribosomal protein L20; TIGRFAM: Ribosomal protein L20; IMG reference gene:2504586757; PFAM: Ribosomal protein L20; TIGRFAM: ribosomal protein L20 YP_004413696.1 InterPro IPR001706:IPR021137; KEGG: vpr:Vpar_1168 ribosomal protein L35; PFAM: Ribosomal protein L35; SPTR: 50S ribosomal protein L35; TIGRFAM: Ribosomal protein L35, non-mitochondrial; IMG reference gene:2504586758; PFAM: Ribosomal protein L35; TIGRFAM: ribosomal protein L35 YP_004413697.1 COGs: COG0290 Translation initiation factor 3 (IF-3); HAMAP: Translation initiation factor 3; InterPro IPR001288:IPR019814:IPR019815; KEGG: vpr:Vpar_1169 translation initiation factor IF-3; PFAM: Translation initiation factor 3, N-terminal; Translation initiation factor 3, C-terminal; SPTR: Translation initiation factor IF-3; TIGRFAM: Translation initiation factor 3; IMG reference gene:2504586759; PFAM: Translation initiation factor IF-3, C-terminal domain; Translation initiation factor IF-3, N-terminal domain; TIGRFAM: translation initiation factor IF-3 YP_004413698.1 InterPro IPR007838; KEGG: tjr:TherJR_1869 protein of unknown function DUF710; PFAM: Cell division protein ZapA-like; SPTR: Putative product ZapA; IMG reference gene:2504586760; PFAM: Cell division protein ZapA YP_004413699.1 COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; InterProIPR005121:IPR005147:IPR005146:IPR004532:IPR 002547; KEGG: vpr:Vpar_1067 phenylalanyl-tRNA synthetase, beta subunit; PFAM: B3/B4 tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; tRNA-binding domain; SMART: B3/B4 tRNA-binding domain; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; tRNA synthetase, B5; SPTR: Phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; IMG reference gene:2504586761; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial YP_004413700.1 COGs: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; InterPro IPR004529:IPR004188:IPR002319; KEGG: vpr:Vpar_1068 phenylalanyl-tRNA synthetase, alpha subunit; PFAM: Phenylalanyl-tRNA synthetase; Phenylalanyl-tRNA synthetase, class II, N-terminal; SPTR: Phenylalanyl-tRNA synthetase alpha chain; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504586762; PFAM: tRNA synthetases class II core domain (F); Aminoacyl tRNA synthetase class II, N-terminal domain; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit YP_004413701.1 COGs: COG0803 ABC-type metal ion transport system periplasmic component/surface adhesin; InterPro IPR006127; KEGG: dae:Dtox_0333 periplasmic solute binding protein; PFAM: ABC transporter metal-binding lipoprotein; SPTR: Putative adhesion lipoprotein; IMG reference gene:2504586763; PFAM: Periplasmic solute binding protein family YP_004413702.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: vpr:Vpar_0936 integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Integrase/recombinase XerD-like protein; IMG reference gene:2504586764; PFAM: Phage integrase, N-terminal SAM-like domain; Phage integrase family YP_004413703.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006675:IPR006674; KEGG: cth:Cthe_0898 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative HD domain protein; IMG reference gene:2504586765; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG YP_004413704.1 KEGG: ele:Elen_2024 Hpt protein; SPTR: Putative hybrid sensory kinase; IMG reference gene:2504586766; PFAM: Hpt domain YP_004413705.1 COGs: COG1720 conserved hypothetical protein; InterPro IPR001378; KEGG: ckn:Calkro_2320 hypothetical protein; PFAM: Uncharacterised protein family UPF0066; SPTR: Protein VirR; TIGRFAM: Uncharacterised protein family UPF0066; IMG reference gene:2504586767; PFAM: Uncharacterised protein family UPF0066; TIGRFAM: putative methyltransferase, YaeB/AF_0241 family YP_004413706.1 COGs: COG0060 Isoleucyl-tRNA synthetase; HAMAP: Isoleucyl-tRNA synthetase, class Ia; InterPro IPR002301:IPR002300:IPR013155; KEGG: csh:Closa_2895 isoleucyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class Ia; Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding; PRIAM: Isoleucine--tRNA ligase; SPTR: Isoleucyl-tRNA synthetase; TIGRFAM: Isoleucyl-tRNA synthetase, class Ia; IMG reference gene:2504586768; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: isoleucyl-tRNA synthetase YP_004413707.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1342 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Putative TonB-dependent receptor plug domain protein; IMG reference gene:2504586769; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004413708.1 KEGG: tde:TDE0975 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586770 YP_004413709.1 COGs: COG1297 membrane protein; InterPro IPR004814:IPR004813; KEGG: vpr:Vpar_1656 oligopeptide transporter, OPT family; PFAM: Oligopeptide transporter OPT superfamily; SPTR: Oligopeptide transporter, OPT family; TIGRFAM: Oligopeptide transporter OPT; Oligopeptide transporter OPT superfamily; IMG reference gene:2504586771; PFAM: OPT oligopeptide transporter protein; TIGRFAM: putative oligopeptide transporter, OPT family; oligopeptide transporters, OPT superfamily YP_004413710.1 COGs: COG4115 conserved hypothetical protein; InterPro IPR009614; KEGG: dhd:Dhaf_2026 addiction module toxin, Txe/YoeB family; PFAM: Addiction module toxin, Txe/YoeB; SPTR: Addiction module toxin, Txe/YoeB family; TIGRFAM: Addiction module toxin, Txe/YoeB; IMG reference gene:2504586772; PFAM: Plasmid encoded toxin Txe; TIGRFAM: toxin-antitoxin system, toxin component, Txe/YoeB family YP_004413711.1 InterPro IPR007337; KEGG: cco:CCC13826_1068 addiction module antitoxin; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504586773; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004413712.1 COGs: COG0793 Periplasmic protease; InterPro IPR001478:IPR005151:IPR004447; KEGG: pth:PTH_2744 periplasmic protease; PFAM: Peptidase S41; PDZ/DHR/GLGF; SMART: Peptidase S41; PDZ/DHR/GLGF; SPTR: C-processing peptidase; TIGRFAM: Peptidase S41A, C-terminal peptidase; IMG reference gene:2504586774; PFAM: Peptidase family S41; PDZ domain (Also known as DHR or GLGF); TIGRFAM: C-terminal peptidase (prc) YP_004413713.1 COGs: COG4942 Membrane-bound metallopeptidase; InterPro IPR016047; KEGG: vpr:Vpar_0809 peptidase M23; PFAM: Peptidase M23; SPTR: Membrane protein metalloendopeptidase; IMG reference gene:2504586775; PFAM: Peptidase family M23 YP_004413714.1 COGs: COG2177 Cell division protein; InterPro IPR003838; KEGG: afn:Acfer_0658 protein of unknown function DUF214; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Cell division ABC transporter, permease protein FtsX; IMG reference gene:2504586776; PFAM: Predicted permease YP_004413715.1 COGs: COG2884 ATPase involved in cell division; InterPro IPR003439:IPR003593:IPR005286; KEGG: afn:Acfer_0657 cell division ATP-binding protein FtsE; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division ATP-binding protein FtsE; TIGRFAM: Cell division ATP-binding protein FtsE; IMG reference gene:2504586777; PFAM: ABC transporter; TIGRFAM: cell division ATP-binding protein FtsE YP_004413716.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR000023; KEGG: tai:Taci_1743 6-phosphofructokinase; PFAM: Phosphofructokinase domain; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase, pyrophosphate-dependent; IMG reference gene:2504586778; PFAM: Phosphofructokinase YP_004413717.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: afn:Acfer_0715 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate aminotransferase; IMG reference gene:2504586779; PFAM: Aminotransferase class I and II YP_004413718.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: aar:Acear_0547 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Nitrite reductase heme biosynthesis H protein; IMG reference gene:2504586780 YP_004413719.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019888; KEGG: nth:Nther_1129 putative transcriptional regulator, AsnC family; SMART: Transcription regulator AsnC-type; SPTR: Putative NirD protein; IMG reference gene:2504586781 YP_004413720.1 COGs: COG0218 GTPase; InterPro IPR019987:IPR002917:IPR005225; KEGG: afn:Acfer_0507 ribosome biogenesis GTP-binding protein YsxC; PFAM: GTP-binding protein, HSR1-related; SPTR: Probable GTP-binding protein engB; TIGRFAM: GTP-binding protein, ribosome biogenesis, YsxC; Small GTP-binding protein; IMG reference gene:2504586782; PFAM: GTPase of unknown function; TIGRFAM: ribosome biogenesis GTP-binding protein YsxC/EngB; small GTP-binding protein domain YP_004413721.1 COGs: COG0466 ATP-dependent Lon protease; InterProIPR004815:IPR003111:IPR003959:IPR008269:IPR 003593; KEGG: tjr:TherJR_2560 ATP-dependent protease La; PFAM: Peptidase S16, Lon C-terminal; Peptidase S16, lon N-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: Peptidase S16, lon N-terminal; ATPase, AAA+ type, core; SPTR: ATP-dependent protease La; TIGRFAM: Peptidase S16, ATP-dependent protease La; IMG reference gene:2504586783; PFAM: ATP-dependent protease La (LON) domain; ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: ATP-dependent protease La YP_004413722.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterProIPR004487:IPR013093:IPR003593:IPR019489:IPR 010603; KEGG: toc:Toce_1766 ATP-dependent Clp protease ATP-binding subunit ClpX; PFAM: ATPase, AAA-2; Clp ATPase, C-terminal; Zinc finger, C4-type; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX; IMG reference gene:2504586784; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; ClpX C4-type zinc finger; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004413723.1 COGs: COG0740 Protease subunit of ATP-dependent Clp protease; InterPro IPR001907; KEGG: drm:Dred_2562 ATP-dependent Clp protease proteolytic subunit; PFAM: Peptidase S14, ClpP; PRIAM: Endopeptidase Clp; SPTR: ATP-dependent Clp protease proteolytic subunit; TIGRFAM: Peptidase S14, ClpP; IMG reference gene:2504586785; PFAM: Clp protease; TIGRFAM: ATP-dependent Clp protease, proteolytic subunit ClpP YP_004413724.1 COGs: COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); InterPro IPR008880:IPR008881:IPR001179:IPR005215; KEGG: vpr:Vpar_1259 trigger factor; PFAM: Trigger factor, ribosome-binding, bacterial; Trigger factor, C-terminal, bacterial; Peptidyl-prolyl cis-trans isomerase, FKBP-type; SPTR: Trigger factor; TIGRFAM: Trigger factor; IMG reference gene:2504586786; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Bacterial trigger factor protein (TF); Bacterial trigger factor protein (TF) C-terminus; TIGRFAM: trigger factor YP_004413725.1 COGs: COG0398 conserved hypothetical protein; InterPro IPR015414; KEGG: vpr:Vpar_0747 SNARE associated Golgi protein-related protein; PFAM: SNARE associated Golgi protein; SPTR: Putative membrane protein; IMG reference gene:2504586787; PFAM: SNARE associated Golgi protein YP_004413726.1 SPTR: Glycoprotease family protein; IMG reference gene:2504586788 YP_004413727.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508; KEGG: hmo:HM1_2806 N-acetylmuramoyl-L-alanine amidase, putative; PFAM: Cell wall hydrolase/autolysin, catalytic; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504586789; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004413728.1 SPTR: Putative prophage LambdaLm01, holin; IMG reference gene:2504586790; PFAM: Holin family YP_004413729.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586791 YP_004413730.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586792 YP_004413731.1 InterPro IPR007001; KEGG: eoi:ECO111_p2-031 major tail fiber protein; PFAM: Bacterial shufflon protein, N-terminal; SPTR: Side tail fiber protein; IMG reference gene:2504586793; PFAM: Bacterial shufflon protein, N-terminal constant region YP_004413732.1 InterPro IPR021283; KEGG: reu:Reut_A2411 putative bacteriophage protein; PFAM: Protein of unknown function DUF2612; SPTR: Putative uncharacterized protein; IMG reference gene:2504586794; PFAM: Protein of unknown function (DUF2612) YP_004413733.1 COGs: COG3299 Uncharacterized homolog of phage Mu protein gp47; KEGG: rpf:Rpic12D_2245 putative bacteriophage protein; SPTR: Putative bacteriophage protein; IMG reference gene:2504586795; PFAM: Baseplate J-like protein YP_004413734.1 KEGG: rpf:Rpic12D_2246 hypothetical protein; SPTR: Putative bacteriophage protein; IMG reference gene:2504586796 YP_004413735.1 InterPro IPR008727; KEGG: hoh:Hoch_4775 PaaR repeat-containing protein; PFAM: PAAR motif; SPTR: PAAR repeat-containing protein; IMG reference gene:2504586797; PFAM: PAAR motif YP_004413736.1 KEGG: bmj:BMULJ_01433 putative bacteriophage protein; SPTR: Putative bacteriophage protein; IMG reference gene:2504586798 YP_004413737.1 KEGG: clj:CLJU_c36460 putative hydrolase; SPTR: Putative uncharacterized protein; IMG reference gene:2504586799 YP_004413738.1 SPTR: Putative bacteriophage protein; IMG reference gene:2504586800 YP_004413739.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586801 YP_004413740.1 KEGG: afn:Acfer_1344 hypothetical protein; SPTR: Phage-related tail protein; IMG reference gene:2504586802 YP_004413741.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586803 YP_004413742.1 InterPro IPR021695; KEGG: bmj:BMULJ_01425 putative bacteriophage protein; PFAM: Protein of unknown function DUF3277; SPTR: Putative bacteriophage protein; IMG reference gene:2504586804; PFAM: Protein of unknown function (DUF3277) YP_004413743.1 InterPro IPR021808; KEGG: sty:STY1058 hypothetical protein; PFAM: Protein of unknown function DUF3383; SPTR: Putative bacteriophage protein; IMG reference gene:2504586805; PFAM: Protein of unknown function (DUF3383) YP_004413744.1 SPTR: Putative aldehyde dehydrogenase; IMG reference gene:2504586806 YP_004413745.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586807 YP_004413746.1 KEGG: abm:ABSDF2474 putative bacteriophage protein; SPTR: Putative bacteriophage protein; manually curated; IMG reference gene:2504586808 YP_004413747.1 KEGG: bgl:bglu_1g15630 putative bacteriophage protein; SPTR: Putative bacteriophage protein; IMG reference gene:2504586809 YP_004413748.1 SPTR: 2-nitropropane dioxygenase; IMG reference gene:2504586810 YP_004413749.1 COGs: COG4834 conserved hypothetical protein; InterPro IPR020049; KEGG: bmj:BMULJ_01418 putative bacteriophage protein; PFAM: Protein of unknown function DUF2184; SPTR: Putative bacteriophage protein; IMG reference gene:2504586811; PFAM: Uncharacterized protein conserved in bacteria (DUF2184) YP_004413750.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586812 YP_004413751.1 COGs: COG3566 conserved hypothetical protein; InterPro IPR019246; KEGG: rpf:Rpic12D_2263 putative bacteriophage protein; PFAM: Protein of unknown function DUF2213; SPTR: Putative bacteriophage protein; IMG reference gene:2504586813; PFAM: Uncharacterized protein conserved in bacteria (DUF2213) YP_004413752.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586814 YP_004413753.1 InterPro IPR006528; KEGG: clj:CLJU_c36440 putative phage-like protein; PFAM: Phage putative head morphogenesis protein, SPP1 gp7; SPTR: Phage putative head morphogeneis protein, SPP1 gp7; IMG reference gene:2504586815; PFAM: Phage Mu protein F like protein YP_004413754.1 KEGG: ypp:YPDSF_0643 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586816 YP_004413755.1 COGs: COG3567 conserved hypothetical protein; InterPro IPR006445; KEGG: bcj:BCAM1064 hypothetical protein; SPTR: Phage-associated protein, HI1409 family; TIGRFAM: Phage-related protein HI1409; IMG reference gene:2504586817; PFAM: Protein of unknown function (DUF1073); TIGRFAM: phage-related protein, HI1409 family YP_004413756.1 InterPro IPR006437:IPR004921; KEGG: ckr:CKR_1734 hypothetical protein; SPTR: Phage terminase, large subunit, PBSX family; TIGRFAM: Phage terminase, large subunit, PBSX; IMG reference gene:2504586818; PFAM: Terminase-like family; TIGRFAM: phage terminase, large subunit, PBSX family YP_004413757.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586819 YP_004413758.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586820 YP_004413759.1 COGs: COG3617 Prophage antirepressor; InterPro IPR003497; KEGG: cdc:CD196_1442 hypothetical protein; PFAM: BRO, N-terminal; SPTR: Toxin-antitoxin system, toxin component, Bro family; IMG reference gene:2504586821; PFAM: BRO family, N-terminal domain YP_004413760.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586822 YP_004413761.1 InterPro IPR001387; KEGG: ljf:FI9785_1788 hypothetical protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586823; PFAM: Helix-turn-helix YP_004413762.1 COGs: COG2369 conserved hypothetical protein homolog of phage Mu protein gp30; InterPro IPR006528; KEGG: clj:CLJU_c36440 putative phage-like protein; PFAM: Phage putative head morphogenesis protein, SPP1 gp7; SPTR: Phage putative head morphogeneis protein, SPP1 gp7; TIGRFAM: Phage putative head morphogenesis protein, SPP1 gp7; IMG reference gene:2504586824; PFAM: Phage Mu protein F like protein; TIGRFAM: phage putative head morphogenesis protein, SPP1 gp7 family YP_004413763.1 KEGG: amt:Amet_2583 putative sigma factor; SPTR: Putative uncharacterized protein; IMG reference gene:2504586825 YP_004413764.1 COGs: COG4570 Holliday junction resolvase; InterPro IPR008822; KEGG: bsu:BSU26250 putative Holliday junction resolvase; skin element; PFAM: Endodeoxyribonuclease, RusA-like; SPTR: Endodeoxyribonuclease RusA; IMG reference gene:2504586826; PFAM: Endodeoxyribonuclease RusA YP_004413765.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: dsy:DSY2197 hypothetical protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504586827; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004413766.1 InterPro IPR007710; PFAM: Nucleoside 2-deoxyribosyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2504586828; PFAM: Nucleoside 2-deoxyribosyltransferase YP_004413767.1 COGs: COG1484 DNA replication protein; InterPro IPR003593:IPR002611; KEGG: amt:Amet_2601 IstB ATP binding domain-containing protein; PFAM: IstB-like ATP-binding protein; SMART: ATPase, AAA+ type, core; SPTR: Putative primosomal protein DnaI; IMG reference gene:2504586829; PFAM: IstB-like ATP binding protein YP_004413768.1 InterPro IPR010056:IPR006343; KEGG: cbi:CLJ_B1878 putative phage replisome organizer; PFAM: Phage replisome organiser, putative, N-terminal; Replication protein, DnaD/DnaB domain; SPTR: Putative phage-associated protein; TIGRFAM: Phage replisome organiser, putative, N-terminal; Replication protein, DnaD/DnaB domain; IMG reference gene:2504586830; PFAM: N-terminal phage replisome organiser (Phage_rep_org_N); Replication initiation and membrane attachment protein (DnaB); TIGRFAM: phage replisome organizer, putative, N-terminal region YP_004413769.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586831 YP_004413770.1 COGs: COG3723 Recombinational DNA repair protein (RecE pathway); InterPro IPR004590:IPR018330; KEGG: tit:Thit_1406 RecT protein; PFAM: DNA single-strand annealing protein RecT-like; SPTR: Protein RecT; TIGRFAM: DNA single-strand annealing protein RecT; IMG reference gene:2504586832; PFAM: RecT family; TIGRFAM: recombinase, phage RecT family YP_004413771.1 COGs: COG5377 Phage-related protein predicted endonuclease; InterPro IPR019080:IPR017482; KEGG: gyc:GYMC61_0602 phage-type endonuclease; PFAM: YqaJ viral recombinase family; SPTR: Phage-type endonuclease family protein; TIGRFAM: Putative phage-type endonuclease; IMG reference gene:2504586833; PFAM: YqaJ-like viral recombinase domain; TIGRFAM: putative phage-type endonuclease YP_004413772.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586834 YP_004413773.1 InterPro IPR018392; PFAM: Peptidoglycan-binding lysin domain; SPTR: XkdP protein; IMG reference gene:2504586835; PFAM: LysM domain YP_004413774.1 InterPro IPR015122; PFAM: Excisionase from transposon Tn916; SPTR: Putative uncharacterized protein; IMG reference gene:2504586836; PFAM: Excisionase from transposon Tn916 YP_004413775.1 KEGG: clj:CLJU_c31700 hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504586837 YP_004413776.1 SPTR: Guanosine-3,5-bis(Diphosphate) 3-diphosphatase, (PpGpp)ase; IMG reference gene:2504586838 YP_004413777.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586839 YP_004413778.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586840 YP_004413779.1 InterPro IPR001387; KEGG: csh:Closa_2770 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Immunity repressor protein; IMG reference gene:2504586841; PFAM: Helix-turn-helix YP_004413780.1 InterPro IPR003477; KEGG: kol:Kole_1306 transcriptional modulator of MazE/toxin, MazF; PFAM: PemK-like protein; SPTR: Toxin-antitoxin system, toxin component, MazF family; IMG reference gene:2504586842; PFAM: PemK-like protein YP_004413781.1 InterPro IPR010359; KEGG: toc:Toce_0399 protein of unknown function DUF955; PFAM: Protein of unknown function DUF955; SPTR: Putative toxin-antitoxin system, toxin component; IMG reference gene:2504586843; PFAM: Domain of unknown function (DUF955) YP_004413782.1 KEGG: bsu:BSU26230 conserved hypothetical protein; skin element; SPTR: Putative uncharacterized protein; IMG reference gene:2504586844 YP_004413783.1 InterPro IPR003477; KEGG: nth:Nther_2959 hypothetical protein; PFAM: PemK-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586845; PFAM: PemK-like protein YP_004413784.1 COGs: COG4974 Site-specific recombinase XerD; InterPro IPR002104; KEGG: deb:DehaBAV1_0846 phage integrase family protein; PFAM: Integrase, catalytic core, phage; SPTR: Site-specific recombinase, phage integrase family; IMG reference gene:2504586846; PFAM: Phage integrase family YP_004413785.1 COGs: COG1597 Sphingosine kinase; InterPro IPR005218:IPR001206; KEGG: cpe:CPE1328 putative lipid kinase; PFAM: Diacylglycerol kinase, catalytic domain; SMART: Diacylglycerol kinase, catalytic domain; SPTR: Diacylglycerol kinase catalytic domain protein; TIGRFAM: Diacylglycerol/lipid kinase; IMG reference gene:2504586848; PFAM: Diacylglycerol kinase catalytic domain; TIGRFAM: lipid kinase, YegS/Rv2252/BmrU family YP_004413786.1 COGs: COG2244 Membrane protein involved in the export of O-antigen and teichoic acid; InterPro IPR002797; KEGG: afn:Acfer_0169 polysaccharide biosynthesis protein; PFAM: Polysaccharide biosynthesis protein; SPTR: Putative stage V sporulation protein B; manually curated; IMG reference gene:2504586849; PFAM: Polysaccharide biosynthesis protein; TIGRFAM: stage V sporulation protein B YP_004413787.1 COGs: COG1085 Galactose-1-phosphate uridylyltransferase; KEGG: bmq:BMQ_1260 hypothetical protein; SPTR: UTP--hexose-1-phosphate uridylyltransferase; IMG reference gene:2504586850 YP_004413788.1 COGs: COG1490 D-Tyr-tRNAtyr deacylase; InterPro IPR003732; KEGG: lcb:LCABL_17530 D-tyrosyl-tRNA(Tyr) deacylase; PFAM: D-tyrosyl-tRNA(Tyr) deacylase; SPTR: D-tyrosyl-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase; IMG reference gene:2504586851; PFAM: D-Tyr-tRNA(Tyr) deacylase; TIGRFAM: D-tyrosyl-tRNA(Tyr) deacylase YP_004413789.1 COGs: COG2267 Lysophospholipase; InterPro IPR001375; KEGG: lsp:Bsph_4253 hypothetical protein; SPTR: Alpha/beta hydrolase; IMG reference gene:2504586852; PFAM: Prolyl oligopeptidase family YP_004413790.1 COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR013709:IPR000891; KEGG: elm:ELI_3982 hypothetical protein; PFAM: Pyruvate carboxyltransferase; 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; PRIAM: 2-isopropylmalate synthase; SMART: 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain; SPTR: 2-isopropylmalate synthase; IMG reference gene:2504586853; PFAM: HMGL-like; LeuA allosteric (dimerisation) domain; TIGRFAM: 2-isopropylmalate synthase, yeast type YP_004413791.1 InterPro IPR022453; KEGG: ckl:CKL_0470 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Zinc finger, YgiT-type; IMG reference gene:2504586854; TIGRFAM: YgiT-type zinc finger domain YP_004413792.1 COGs: COG0180 Tryptophanyl-tRNA synthetase; InterPro IPR002306:IPR002305; KEGG: bvu:BVU_0408 tryptophanyl-tRNA synthetase II; PFAM: Aminoacyl-tRNA synthetase, class Ib; PRIAM: Tryptophan--tRNA ligase; SPTR: Tryptophan--tRNA ligase; TIGRFAM: Tryptophanyl-tRNA synthetase, class Ib; IMG reference gene:2504586855; PFAM: tRNA synthetases class I (W and Y); TIGRFAM: tryptophanyl-tRNA synthetase YP_004413793.1 COGs: COG0476 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 2; InterPro IPR007901:IPR000594; KEGG: ere:EUBREC_0899 hypothetical protein; PFAM: UBA/THIF-type NAD/FAD binding fold; MoeZ/MoeB; SPTR: Thiazole biosynthesis adenylyltransferase ThiF; IMG reference gene:2504586856; PFAM: MoeZ/MoeB domain; ThiF family YP_004413794.1 SPTR: Putative ATP-dependent RNA helicase DDX6; IMG reference gene:2504586857 YP_004413795.1 KEGG: afn:Acfer_0870 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586858 YP_004413796.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_0065 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative receptor; IMG reference gene:2504586859; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004413797.1 InterPro IPR006260; KEGG: gvi:glr1815 hypothetical protein; PFAM: TonB, C-terminal; SPTR: TonB protein; TIGRFAM: TonB, C-terminal; IMG reference gene:2504586860; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004413798.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: vpr:Vpar_1698 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Transport energizing protein, ExbD/TolR family; IMG reference gene:2504586861; PFAM: Biopolymer transport protein ExbD/TolR YP_004413799.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: vpr:Vpar_1341 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family protein; IMG reference gene:2504586862; PFAM: MotA/TolQ/ExbB proton channel family YP_004413800.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: afn:Acfer_0320 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Heme ABC superfamily ATP binding cassette transporter, binding protein; IMG reference gene:2504586863; PFAM: Periplasmic binding protein YP_004413801.1 SPTR: Putative secreted protein; IMG reference gene:2504586864 YP_004413802.1 COGs: COG3663 G:T/U mismatch-specific DNA glycosylase; InterPro IPR005122; KEGG: tkm:TK90_2433 hypothetical protein; PFAM: Uracil-DNA glycosylase-like; SPTR: Putative G/U mismatch-specific DNA glycosylase; IMG reference gene:2504586865; PFAM: Uracil DNA glycosylase superfamily YP_004413803.1 InterPro IPR005531; KEGG: afn:Acfer_1025 protein of unknown function DUF322; PFAM: Alkaline shock protein Asp23; SPTR: Putative uncharacterized protein; IMG reference gene:2504586866; PFAM: Protein of unknown function (DUF322) YP_004413804.1 COGs: COG0613 metal-dependent phosphoesterase (PHP family); InterPro IPR004013:IPR003141; KEGG: slp:Slip_1055 PHP domain protein; PFAM: PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: S-adenosylmethionine:tRNA ribosyltransferase-isomerase; IMG reference gene:2504586867; PFAM: PHP domain YP_004413805.1 COGs: COG2359 conserved hypothetical protein; InterPro IPR007347; KEGG: tmt:Tmath_1216 stage V sporulation protein S; PFAM: Stage V sporulation protein S; SPTR: Stage V sporulation protein S; IMG reference gene:2504586868; PFAM: Stage V sporulation protein S (SpoVS) YP_004413806.1 COGs: COG1692 conserved hypothetical protein; InterPro IPR004843:IPR005235; KEGG: tjr:TherJR_1281 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Ser/Thr protein phosphatase family protein; TIGRFAM: Conserved hypothetical protein CHP00282; IMG reference gene:2504586869; TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family YP_004413807.1 KEGG: mta:Moth_1082 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586870 YP_004413808.1 COGs: COG1418 HD superfamily hydrolase; HAMAP: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; InterProIPR017705:IPR018111:IPR006674:IPR004087:IPR 003607:IPR006675; KEGG: afn:Acfer_0360 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; K Homology, type 1, subgroup; SMART: Metal-dependent phosphohydrolase, HD domain; K Homology; SPTR: HDIG/KH domain protein; TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; Uncharacterised protein family HDIG; IMG reference gene:2504586871; PFAM: KH domain; HD domain; Domain of unknown function (DUF3552); TIGRFAM: conserved hypothetical protein YmdA/YtgF; uncharacterized domain HDIG YP_004413809.1 COGs: COG1606 ATP-utilizing protein of the PP-loop superfamily; InterPro IPR001962:IPR005232; KEGG: toc:Toce_0386 PP-loop domain protein; PFAM: Asparagine synthase; SPTR: PP-loop family protein; TIGRFAM: Conserved hypothetical protein CHP00268; IMG reference gene:2504586872; PFAM: Asparagine synthase; TIGRFAM: TIGR00268 family protein YP_004413810.1 COGs: COG1641 conserved hypothetical protein; HAMAP: Uncharacterised protein family UPF0272; InterPro IPR002822; KEGG: cac:CA_C0774 hypothetical protein; PFAM: Uncharacterised protein family UPF0272; SPTR: Hypothetical cytosolic protein; TIGRFAM: Uncharacterised protein family UPF0272; IMG reference gene:2504586873; PFAM: Protein of unknown function DUF111; TIGRFAM: TIGR00299 family protein YP_004413811.1 COGs: COG1691 NCAIR mutase (PurE)-related protein; InterPro IPR000031; KEGG: chy:CHY_1282 hypothetical protein; PFAM: Phosphoribosylaminoimidazole carboxylase, core; SPTR: Putative AIR carboxylase; manually curated; IMG reference gene:2504586874; PFAM: AIR carboxylase YP_004413812.1 KEGG: afn:Acfer_1402 hypothetical protein; SPTR: Putative ATPase subunit H; IMG reference gene:2504586875 YP_004413813.1 COGs: COG0669 Phosphopantetheine adenylyltransferase; InterPro IPR004821:IPR004820:IPR001980; KEGG: vpr:Vpar_0836 pantetheine-phosphate adenylyltransferase; PFAM: Cytidylyltransferase; PRIAM: Pantetheine-phosphate adenylyltransferase; SPTR: Phosphopantetheine adenylyltransferase; TIGRFAM: Coenzyme A biosynthesis protein; Cytidyltransferase-related; IMG reference gene:2504586876; PFAM: Cytidylyltransferase; TIGRFAM: pantetheine-phosphate adenylyltransferase, bacterial; cytidyltransferase-related domain YP_004413814.1 COGs: COG0742 N6-adenine-specific methylase; InterPro IPR004398; KEGG: sth:STH1438 putative RNA methylase; PFAM: RNA methyltransferase, RsmD; SPTR: RNA methyltransferase, RsmD family; TIGRFAM: RNA methyltransferase, RsmD; IMG reference gene:2504586877; PFAM: Conserved hypothetical protein 95; TIGRFAM: RNA methyltransferase, RsmD family YP_004413815.1 KEGG: afn:Acfer_1405 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586878 YP_004413816.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586880 YP_004413817.1 COGs: COG0053 Co/Zn/Cd cation transporter; InterPro IPR002524; KEGG: eel:EUBELI_00361 hypothetical protein; PFAM: Cation efflux protein; SPTR: Cation efflux family protein; TIGRFAM: Cation efflux protein; IMG reference gene:2504586881; PFAM: Cation efflux family; TIGRFAM: cation diffusion facilitator family transporter YP_004413818.1 COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: cbe:Cbei_1409 putative aminopeptidase 1; PFAM: Peptidase M18; SPTR: M18 family aminopeptidase; IMG reference gene:2504586882; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004413819.1 COGs: COG0042 tRNA-dihydrouridine synthase; InterPro IPR001269:IPR004652; KEGG: amt:Amet_4527 nifR3 family TIM-barrel protein; PFAM: tRNA-dihydrouridine synthase; SPTR: tRNA-dihydrouridine synthase; TIGRFAM: tRNA-dihydrouridine synthase, TIM-barrel, NifR3; IMG reference gene:2504586883; PFAM: Dihydrouridine synthase (Dus); TIGRFAM: putative TIM-barrel protein, nifR3 family YP_004413820.1 COGs: COG1521 Putative transcriptional regulator protein; InterPro IPR004619; KEGG: pth:PTH_0258 pantothenate kinase; PFAM: Type III pantothenate kinase; PRIAM: Pantothenate kinase; SPTR: Type III pantothenate kinase; TIGRFAM: Type III pantothenate kinase; IMG reference gene:2504586884; PFAM: Bordetella pertussis Bvg accessory factor family; TIGRFAM: pantothenate kinase, type III YP_004413821.1 COGs: COG0340 Biotin-(acetyl-CoA carboxylase) ligase; InterPro IPR013196:IPR004143:IPR003142:IPR004408; KEGG: afn:Acfer_1595 biotin/acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase; Helix-turn-helix, type 11; Biotin protein ligase, C-terminal; PRIAM: Biotin--[acetyl-CoA-carboxylase] ligase; SPTR: Biotin-[acetyl-CoA-carboxylase] ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; IMG reference gene:2504586885; PFAM: HTH domain; Biotin protein ligase C terminal domain; Biotin/lipoate A/B protein ligase family; TIGRFAM: birA, biotin-[acetyl-CoA-carboxylase] ligase region; BirA biotin operon repressor domain YP_004413822.1 COGs: COG0465 ATP-dependent Zn protease; InterProIPR011546:IPR003959:IPR000642:IPR003593:IPR 005936; KEGG: afn:Acfer_1596 ATP-dependent metalloprotease FtsH; PFAM: Peptidase M41; ATPase, AAA-type, core; Peptidase M41, FtsH extracellular; PRIAM: Microtubule-severing ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cell division protein FtsH; TIGRFAM: Peptidase M41, FtsH; IMG reference gene:2504586886; PFAM: FtsH Extracellular; Peptidase family M41; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent metalloprotease FtsH YP_004413823.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cth:Cthe_1563 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: D-methionine ABC transporter, ATP-binding protein; IMG reference gene:2504586887; PFAM: ABC transporter YP_004413824.1 InterPro IPR003838; KEGG: cth:Cthe_1562 hypothetical protein; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Putative permease; IMG reference gene:2504586888; PFAM: Predicted permease YP_004413825.1 KEGG: gva:HMPREF0424_0366 hypothetical protein; SPTR: Putative integral membrane protein; IMG reference gene:2504586889 YP_004413826.1 COGs: COG2206 HD-GYP domain; InterPro IPR021812:IPR003607:IPR006674; KEGG: cth:Cthe_0898 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; Protein of unknown function DUF3391; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative HD-GYP domain containing protein; IMG reference gene:2504586890; PFAM: Domain of unknown function (DUF3391); HD domain YP_004413827.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674; KEGG: nth:Nther_2124 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SPTR: Putative HD domain protein; IMG reference gene:2504586891; PFAM: HD domain YP_004413828.1 COGs: COG2206 HD-GYP domain; InterPro IPR006674:IPR003607; KEGG: hor:Hore_22020 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative HD-GYP domain containing protein; IMG reference gene:2504586892; PFAM: HD domain YP_004413829.1 COGs: COG0542 ATPase with chaperone activity ATP-binding subunit; InterProIPR017730:IPR003959:IPR013093:IPR003593:IPR 004176:IPR019489; KEGG: tjr:TherJR_0928 ATP-dependent chaperone ClpB; PFAM: ATPase, AAA-2; ATPase, AAA-type, core; Clp, N-terminal; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent chaperone protein ClpB; TIGRFAM: Chaperonin ClpB; IMG reference gene:2504586893; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB YP_004413830.1 COGs: COG4679 Phage-related protein; InterPro IPR009241; KEGG: bpb:bpr_I0707 hypothetical protein; PFAM: Protein of unknown function DUF891; SPTR: Toxin-antitoxin system, toxin component, RelE family; IMG reference gene:2504586894; PFAM: Phage derived protein Gp49-like (DUF891) YP_004413831.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586896 YP_004413832.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: vpr:Vpar_1135 anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Cobalt chelatase; IMG reference gene:2504586897; PFAM: Cobalt chelatase (CbiK) YP_004413833.1 COGs: COG2217 Cation transport ATPase; InterProIPR006403:IPR006121:IPR001757:IPR008250:IPR 006122:IPR006416:IPR005834; KEGG: ere:EUBREC_0615 heavy-metal transporting P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Heavy metal transport/detoxification protein; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-exporting ATPase; TIGRFAM: ATPase, P type, cation/copper-transporter; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; Copper ion-binding; ATPase, P-type, heavy metal translocating; IMG reference gene:2504586898; PFAM: E1-E2 ATPase; Heavy-metal-associated domain; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; copper ion binding protein; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004413834.1 COGs: COG1473 Metal-dependent amidase/aminoacylase/carboxypeptidase; InterPro IPR002933:IPR010168; KEGG: clj:CLJU_c06270 putative amidohydrolase; PFAM: Peptidase M20; PRIAM: N-acetyldiaminopimelate deacetylase; SPTR: Peptidase, M20D family; TIGRFAM: Peptidase M20D, amidohydrolase; IMG reference gene:2504586899; PFAM: Peptidase family M20/M25/M40; Peptidase dimerisation domain; TIGRFAM: amidohydrolase YP_004413835.1 COGs: COG1124 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: dsy:DSY4092 hypothetical protein; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Peptide/opine/nickel uptake ABC transporter family, ATP-binding protein; IMG reference gene:2504586900; PFAM: ABC transporter YP_004413836.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: dhd:Dhaf_1863 oligopeptide/dipeptide ABC transporter, ATPase subunit; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Peptide/opine/nickel uptake ABC transporter family, ATP-binding protein; IMG reference gene:2504586901; PFAM: ABC transporter YP_004413837.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dsy:DSY4094 hypothetical protein; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Peptide/opine/nickel ABC transporter family, permease protein; IMG reference gene:2504586902; PFAM: Binding-protein-dependent transport system inner membrane component YP_004413838.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: dhd:Dhaf_1272 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter, permease protein AppB; IMG reference gene:2504586903; PFAM: Binding-protein-dependent transport system inner membrane component YP_004413839.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: dhd:Dhaf_2550 extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Peptide/opine/nickel ABC transporter family, periplasmic substrate-binding protein; IMG reference gene:2504586904; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004413840.1 COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518; KEGG: cpy:Cphy_0132 MazG family protein; PFAM: NTP pyrophosphohydrolase MazG, putative catalytic core; SPTR: Tetrapyrrole methylase family protein/MazG family protein; IMG reference gene:2504586905; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein YP_004413841.1 COGs: COG0778 Nitroreductase; InterPro IPR000415; KEGG: dap:Dacet_1946 nitroreductase; PFAM: Nitroreductase-like; SPTR: Nitroreductase family protein; IMG reference gene:2504586906; PFAM: Nitroreductase family YP_004413842.1 InterPro IPR011496; KEGG: cpe:CPE1234 hyaluronidase; PFAM: Beta-N-acetylglucosaminidase; PRIAM: Beta-N-acetylhexosaminidase; SPTR: O-GlcNAcase NagJ; IMG reference gene:2504586907; PFAM: beta-N-acetylglucosaminidase YP_004413843.1 COGs: COG0504 CTP synthase (UTP-ammonia lyase); HAMAP: CTP synthase; InterPro IPR004468:IPR017456:IPR000991; KEGG: vpr:Vpar_1584 CTP synthase; PFAM: CTP synthase, N-terminal; Glutamine amidotransferase class-I, C-terminal; PRIAM: CTP synthase; SPTR: CTP synthase; TIGRFAM: CTP synthase; IMG reference gene:2504586908; PFAM: Glutamine amidotransferase class-I; CTP synthase N-terminus; TIGRFAM: CTP synthase YP_004413844.1 InterPro IPR007759; KEGG: dhd:Dhaf_4845 DNA-directed RNA polymerase delta subunit, putative; PFAM: DNA-directed RNA polymerase delta subunit; SPTR: Putative DNA-directed RNA polymerase subunit delta; IMG reference gene:2504586909; PFAM: DNA-directed RNA polymerase delta subunit YP_004413845.1 COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: vpr:Vpar_1585 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; Arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: Arginine--tRNA ligase; SMART: DALR anticodon binding; SPTR: Arginyl-tRNA synthetase; TIGRFAM: Arginyl-tRNA synthetase, class Ic; IMG reference gene:2504586910; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: arginyl-tRNA synthetase YP_004413846.1 COGs: COG4506 conserved hypothetical protein; InterPro IPR015231; KEGG: dhd:Dhaf_4847 domain of unknown function DUF1934; PFAM: Protein of unknown function DUF1934; SPTR: Putative uncharacterized protein; IMG reference gene:2504586911; PFAM: Domain of unknown function (DUF1934) YP_004413847.1 InterPro IPR021147; KEGG: ppm:PPSC2_c5117 hypothetical protein; PFAM: Protein of unknown function DUF697; SPTR: Putative uncharacterized protein; IMG reference gene:2504586912; PFAM: Domain of unknown function (DUF697) YP_004413848.1 COGs: COG3542 conserved hypothetical protein; InterPro IPR009327; KEGG: aac:Aaci_0879 protein of unknown function DUF985; PFAM: Protein of unknown function DUF985; SPTR: Cupin superfamily DUF985; IMG reference gene:2504586913; PFAM: Cupin superfamily (DUF985) YP_004413849.1 InterPro IPR002641; KEGG: clj:CLJU_c03780 putative patatin-like phospholipase; PFAM: Patatin/Phospholipase A2-related; SPTR: Phospholipase, patatin family; IMG reference gene:2504586914; PFAM: Patatin-like phospholipase YP_004413850.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586915 YP_004413851.1 COGs: COG0442 Prolyl-tRNA synthetase; HAMAP: Prolyl-tRNA synthetase, class IIa, bacterial; InterPro IPR004500:IPR002314:IPR007214:IPR004154; KEGG: tjr:TherJR_1368 prolyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; YbaK/aminoacyl-tRNA synthetase-associated domain; Anticodon-binding; SPTR: Proline--tRNA ligase; TIGRFAM: Prolyl-tRNA synthetase, class IIa, bacterial; IMG reference gene:2504586916; PFAM: Anticodon binding domain; YbaK / prolyl-tRNA synthetases associated domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: prolyl-tRNA synthetase, family II YP_004413852.1 COGs: COG0821 Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis; InterPro IPR004588; KEGG: afn:Acfer_1373 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; PFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; SPTR: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; TIGRFAM: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type; IMG reference gene:2504586917; PFAM: GcpE protein; TIGRFAM: 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase YP_004413853.1 COGs: COG0750 membrane-associated Zn-dependent protease 1; InterPro IPR001478:IPR008915:IPR004387; KEGG: afn:Acfer_1374 membrane-associated zinc metalloprotease; PFAM: Peptidase M50; SMART: PDZ/DHR/GLGF; SPTR: RIP metalloprotease RseP; TIGRFAM: Peptidase M50, putative membrane-associated zinc metallopeptidase; IMG reference gene:2504586918; PFAM: Peptidase family M50; TIGRFAM: RIP metalloprotease RseP YP_004413854.1 COGs: COG0743 1-deoxy-D-xylulose 5-phosphate reductoisomerase; InterPro IPR013512:IPR013644:IPR003821; KEGG: afn:Acfer_1375 1-deoxy-D-xylulose 5-phosphate reductoisomerase; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal; 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate reductoisomerase; SPTR: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; IMG reference gene:2504586919; PFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase; 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; TIGRFAM: 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_004413855.1 COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: afn:Acfer_1376 phosphatidate cytidylyltransferase; PFAM: Phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; IMG reference gene:2504586920; PFAM: Cytidylyltransferase family YP_004413856.1 COGs: COG0020 Undecaprenyl pyrophosphate synthase; InterPro IPR001441; KEGG: vpr:Vpar_0861 undecaprenyl diphosphate synthase; PFAM:Di-trans-poly-cis-decaprenylcistransferase-lik e; PRIAM: Di-trans,poly-cis-decaprenylcistransferase; SPTR: Di-trans,poly-cis-decaprenylcistransferase; TIGRFAM:Di-trans-poly-cis-decaprenylcistransferase- like; IMG reference gene:2504586921; PFAM: Putative undecaprenyl diphosphate synthase; TIGRFAM: undecaprenyl diphosphate synthase YP_004413857.1 COGs: COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase; InterPro IPR011545:IPR001650:IPR014001:IPR005259; KEGG: afn:Acfer_0309 primosomal protein N'; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Primosomal protein; TIGRFAM: Primosomal protein n; IMG reference gene:2504586922; PFAM: Helicase conserved C-terminal domain; DEAD/DEAH box helicase; TIGRFAM: primosomal protein N' YP_004413858.1 COGs: COG3584 conserved hypothetical protein; InterPro IPR002477:IPR010611; KEGG: vpr:Vpar_0605 3D domain protein; PFAM: 3D; Peptidoglycan binding-like; SPTR: LysM domain protein; IMG reference gene:2504586923; PFAM: Putative peptidoglycan binding domain; 3D domain YP_004413859.1 COGs: COG0336 tRNA-(guanine-N1)-methyltransferase; HAMAP: tRNA (guanine-N1-)-methyltransferase, bacteria; InterPro IPR002649:IPR016009; KEGG: ppm:PPSC2_c2063 tRNA (guanine-n1)-methyltransferase; PFAM: tRNA (guanine-N1-)-methyltransferase; PRIAM: tRNA (guanine-N(1)-)-methyltransferase; SPTR: tRNA (guanine-N(1)-)-methyltransferase; TIGRFAM: tRNA (guanine-N1-)-methyltransferase, bacteria; IMG reference gene:2504586924; PFAM: tRNA (Guanine-1)-methyltransferase; TIGRFAM: tRNA (guanine-N1)-methyltransferase YP_004413860.1 COGs: COG0806 RimM protein required for 16S rRNA processing; HAMAP: 16S rRNA processing protein RimM; InterPro IPR011961:IPR002676:IPR007903; KEGG: dau:Daud_0659 16S rRNA processing protein RimM; PFAM: RimM protein; PRC-barrel; SPTR: Ribosome maturation factor rimM; TIGRFAM: 16S rRNA processing protein RimM; IMG reference gene:2504586925; PFAM: PRC-barrel domain; RimM N-terminal domain; TIGRFAM: 16S rRNA processing protein RimM YP_004413861.1 InterPro IPR021297; KEGG: tjr:TherJR_2048 hypothetical protein; PFAM: Protein of unknown function DUF2869; SPTR: Putative uncharacterized protein; IMG reference gene:2504586926; PFAM: Protein of unknown function (DUF2869) YP_004413862.1 COGs: COG1837 RNA-binding protein (contains KH domain); InterPro IPR018111; KEGG: bpb:bpr_I1564 RNA binding protein; SPTR: KH domain protein; IMG reference gene:2504586927; PFAM: KH domain YP_004413863.1 COGs: COG0228 Ribosomal protein S16; InterPro IPR000307; KEGG: afn:Acfer_0467 ribosomal protein S16; PFAM: Ribosomal protein S16; SPTR: 30S ribosomal protein S16; TIGRFAM: Ribosomal protein S16; IMG reference gene:2504586928; PFAM: Ribosomal protein S16; TIGRFAM: ribosomal protein S16 YP_004413864.1 COGs: COG0541 Signal recognition particle GTPase; InterProIPR004125:IPR013822:IPR003593:IPR000897:IPR 004780; KEGG: tjr:TherJR_2051 signal recognition particle protein; PFAM: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, M-domain; Signal recognition particle, SRP54 subunit, helical bundle; SMART: Signal recognition particle, SRP54 subunit, GTPase; Signal recognition particle, SRP54 subunit, helical bundle; ATPase, AAA+ type, core; SPTR: Signal recognition particle protein; TIGRFAM: Signal recognition particle, SRP; IMG reference gene:2504586929; PFAM: SRP54-type protein, GTPase domain; SRP54-type protein, helical bundle domain; Signal peptide binding domain; TIGRFAM: signal recognition particle-docking protein FtsY; signal recognition particle protein YP_004413865.1 COGs: COG2739 conserved hypothetical protein; InterPro IPR007394; KEGG: slp:Slip_0905 putative helix-turn-helix protein YlxM/p13 family protein; PFAM: Putative helix-turn-helix protein, YlxM/p13-like; SPTR: UPF0122 protein SELSPUOL_00762; IMG reference gene:2504586930; PFAM: Putative helix-turn-helix protein, YlxM / p13 like YP_004413866.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504586931 YP_004413867.1 COGs: COG1190 Lysyl-tRNA synthetase (class II); HAMAP: Lysyl-tRNA synthetase, class II; InterPro IPR002313:IPR004365:IPR004364; KEGG: bmd:BMD_0098 lysyl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (D/K/N); Nucleic acid binding, OB-fold, tRNA/helicase-type; PRIAM: Lysine--tRNA ligase; SPTR: Lysyl-tRNA synthetase; TIGRFAM: Lysyl-tRNA synthetase, class II; IMG reference gene:2504586932; PFAM: tRNA synthetases class II (D, K and N); OB-fold nucleic acid binding domain; TIGRFAM: lysyl-tRNA synthetase, eukaryotic and non-spirochete bacterial YP_004413868.1 COGs: COG0782 Transcription elongation factor; InterPro IPR022691:IPR001437:IPR006359; KEGG: nth:Nther_0116 transcription elongation factor GreA; PFAM: Transcription elongation factor, GreA/GreB, C-terminal; Transcription elongation factor, GreA/GreB, N-terminal; SPTR: Transcription elongation factor; TIGRFAM: Transcription elongation factor GreA; IMG reference gene:2504586933; PFAM: domain; Transcription elongation factor, GreA/GreB, C-term; TIGRFAM: transcription elongation factor GreA YP_004413869.1 COGs: COG2827 endonuclease containing a URI domain; InterPro IPR000305; KEGG: cno:NT01CX_2293 endo/excinuclease domain-containing protein; PFAM: Excinuclease ABC, C subunit, N-terminal; SMART: Excinuclease ABC, C subunit, N-terminal; SPTR: Endo/excinuclease domain protein; IMG reference gene:2504586934; PFAM: GIY-YIG catalytic domain YP_004413870.1 COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130; KEGG: afn:Acfer_0194 peptidyl-prolyl cis-trans isomerase cyclophilin type; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; PRIAM: Peptidylprolyl isomerase; SPTR: Peptidyl-prolyl cis-trans isomerase; IMG reference gene:2504586935; PFAM: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YP_004413871.1 KEGG: vpr:Vpar_1710 hypothetical protein; SPTR: Putative metal dependent hydrolase; IMG reference gene:2504586936 YP_004413872.1 COGs: COG3177 conserved hypothetical protein; InterPro IPR003812; KEGG: hpc:HPPC_08204 R2; PFAM: Filamentation induced by cAMP/death on curing-related; SPTR: Putative filamentation induced by cAMP protein Fic; IMG reference gene:2504586937; PFAM: Fic/DOC family YP_004413873.1 InterPro IPR014998; KEGG: afn:Acfer_0800 hypothetical protein; PFAM: Protein of unknown function DUF1848; SPTR: Putative uncharacterized protein; IMG reference gene:2504586938; PFAM: Domain of unknown function (DUF1848) YP_004413874.1 COGs: COG0115 Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase; InterPro IPR001544:IPR005786; KEGG: eel:EUBELI_01912 branched-chain amino acid aminotransferase; PFAM: Aminotransferase, class IV; PRIAM: Branched-chain-amino-acid transaminase; SPTR: Branched-chain-amino-acid transaminase; TIGRFAM: Branched-chain amino acid aminotransferase II; IMG reference gene:2504586939; PFAM: Aminotransferase class IV; TIGRFAM: branched-chain amino acid aminotransferase, group II YP_004413875.1 KEGG: afn:Acfer_1798 protein tyrosine phosphatase II superfamily protein; SPTR: Putative phytase; IMG reference gene:2504586940 YP_004413876.1 InterPro IPR005546:IPR006626:IPR006315; KEGG: bch:Bcen2424_6767 outer membrane autotransporter; PFAM: Autotransporter beta-domain; SMART: Autotransporter beta-domain; Parallel beta-helix repeat; SPTR: Putative autotransporter beta-domain protein; TIGRFAM: Outer membrane autotransporter barrel; IMG reference gene:2504586941 YP_004413877.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: vpr:Vpar_0944 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: SmtA protein; IMG reference gene:2504586943; PFAM: Methyltransferase domain YP_004413878.1 COGs: COG0203 Ribosomal protein L17; InterPro IPR000456; KEGG: ppy:PPE_04249 50S ribosomal protein L17; PFAM: Ribosomal protein L17; SPTR: 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; IMG reference gene:2504586944; PFAM: Ribosomal protein L17; TIGRFAM: ribosomal protein L17 YP_004413879.1 COGs: COG0202 DNA-directed RNA polymerase alpha subunit/40 kD subunit; InterProIPR011260:IPR011263:IPR011262:IPR011773:IPR 011261; KEGG: tjr:TherJR_0324 DNA-directed RNA polymerase, alpha subunit; PFAM: RNA polymerase, alpha subunit, C-terminal; DNA-directed RNA polymerase, insert domain; DNA-directed RNA polymerase, dimerisation; PRIAM: DNA-directed RNA polymerase; SMART: DNA-directed RNA polymerase, RpoA/D/Rpb3-type; SPTR: DNA-directed RNA polymerase subunit alpha; TIGRFAM: DNA-directed RNA polymerase, alpha subunit; IMG reference gene:2504586945; PFAM: RNA polymerase Rpb3/Rpb11 dimerisation domain; RNA polymerase Rpb3/RpoA insert domain; Bacterial RNA polymerase, alpha chain C terminal domain; TIGRFAM: DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type YP_004413880.1 COGs: COG0522 Ribosomal protein S4 and related protein; InterPro IPR005709:IPR002942:IPR001912; KEGG: afn:Acfer_1903 ribosomal protein S4; PFAM: RNA-binding S4; Ribosomal protein S4/S9, N-terminal; SMART: RNA-binding S4; SPTR: 30S ribosomal protein S4; TIGRFAM: Ribosomal protein S4, bacterial-type; IMG reference gene:2504586946; PFAM: Ribosomal protein S4/S9 N-terminal domain; S4 domain; TIGRFAM: ribosomal protein S4, bacterial/organelle type YP_004413881.1 COGs: COG0100 Ribosomal protein S11; InterPro IPR001971:IPR019981; KEGG: ppm:PPSC2_c4748 30S ribosomal protein S11; PFAM: Ribosomal protein S11; SPTR: 30S ribosomal protein S11; TIGRFAM: Ribosomal protein S11, bacterial-type; IMG reference gene:2504586947; PFAM: Ribosomal protein S11; TIGRFAM: 30S ribosomal protein S11 YP_004413882.1 COGs: COG0099 Ribosomal protein S13; InterPro IPR001892:IPR019980; KEGG: sti:Sthe_1061 ribosomal protein S13; PFAM: Ribosomal protein S13; SPTR: 30S ribosomal protein S13; TIGRFAM: Ribosomal protein S13, bacterial-type; IMG reference gene:2504586948; PFAM: Ribosomal protein S13/S18; TIGRFAM: 30S ribosomal protein S13 YP_004413883.1 HAMAP: Ribosomal protein L36; InterPro IPR000473; KEGG: afn:Acfer_1906 ribosomal protein L36; PFAM: Ribosomal protein L36; SPTR: 50S ribosomal protein L36; TIGRFAM: Ribosomal protein L36; IMG reference gene:2504586949; PFAM: Ribosomal protein L36; TIGRFAM: ribosomal protein L36, bacterial type YP_004413884.1 COGs: COG0361 Translation initiation factor 1 (IF-1); HAMAP: Translation initiation factor IF-1; InterPro IPR004368:IPR006196:IPR022967; KEGG: vpr:Vpar_1471 translation initiation factor IF-1; PFAM: RNA-binding domain, S1, IF1 type; SMART: RNA-binding domain, S1; SPTR: Translation initiation factor IF-1; TIGRFAM: Translation initiation factor IF-1; IMG reference gene:2504586950; PFAM: Translation initiation factor 1A / IF-1; TIGRFAM: translation initiation factor IF-1 YP_004413885.1 COGs: COG0563 Adenylate kinase and related kinase; InterPro IPR006259:IPR007862:IPR000850; KEGG: afn:Acfer_1908 adenylate kinase; PFAM: Adenylate kinase; Adenylate kinase, active site lid domain; SPTR: Adenylate kinase; TIGRFAM: Adenylate kinase, subfamily; IMG reference gene:2504586951; PFAM: Adenylate kinase, active site lid; Adenylate kinase; TIGRFAM: adenylate kinases YP_004413886.1 COGs: COG0201 Preprotein translocase subunit SecY; InterPro IPR002208; KEGG: afn:Acfer_1909 preprotein translocase, SecY subunit; PFAM: SecY protein; SPTR: Preprotein translocase subunit secY; TIGRFAM: SecY protein; IMG reference gene:2504586952; PFAM: eubacterial secY protein; TIGRFAM: preprotein translocase, SecY subunit YP_004413887.1 COGs: COG0200 Ribosomal protein L15; InterPro IPR021131:IPR005749; KEGG: vpr:Vpar_1475 ribosomal protein L15; PFAM: Ribosomal protein L18e/L15; SPTR: 50S ribosomal protein L15; TIGRFAM: Ribosomal protein L15, bacterial-type; IMG reference gene:2504586953; PFAM: Ribosomal protein L18e/L15; TIGRFAM: ribosomal protein L15, bacterial/organelle YP_004413888.1 COGs: COG1841 Ribosomal protein L30/L7E; InterPro IPR016082:IPR005996; KEGG: vpr:Vpar_1476 ribosomal protein L30; PFAM: Ribosomal protein L30, ferredoxin-like fold domain; SPTR: 50S ribosomal protein L30; TIGRFAM: Ribosomal protein L30, bacterial-type; IMG reference gene:2504586954; PFAM: Ribosomal protein L30p/L7e; TIGRFAM: ribosomal protein L30, bacterial/organelle YP_004413889.1 COGs: COG0098 Ribosomal protein S5; InterPro IPR005712:IPR013810:IPR005324; KEGG: afn:Acfer_1912 ribosomal protein S5; PFAM: Ribosomal protein S5, C-terminal; Ribosomal protein S5, N-terminal; SPTR: 30S ribosomal protein S5; TIGRFAM: Ribosomal protein S5, bacterial-type; IMG reference gene:2504586955; PFAM: Ribosomal protein S5, N-terminal domain; Ribosomal protein S5, C-terminal domain; TIGRFAM: ribosomal protein S5, bacterial/organelle type YP_004413890.1 COGs: COG0256 Ribosomal protein L18; InterPro IPR005484:IPR004389; KEGG: afn:Acfer_1913 ribosomal protein L18; PFAM: Ribosomal protein L18/L5; SPTR: 50S ribosomal protein L18; TIGRFAM: Ribosomal protein L18, bacterial; IMG reference gene:2504586956; PFAM: Ribosomal L18p/L5e family; TIGRFAM: ribosomal protein L18, bacterial type YP_004413891.1 COGs: COG0097 Ribosomal protein L6P/L9E; InterPro IPR019906:IPR020040; KEGG: vpr:Vpar_1479 ribosomal protein L6; PFAM: Ribosomal protein L6, alpha-beta domain; SPTR: 50S ribosomal protein L6; TIGRFAM: Ribosomal protein L6, bacterial-type; IMG reference gene:2504586957; PFAM: Ribosomal protein L6; TIGRFAM: ribosomal protein L6, bacterial type YP_004413892.1 COGs: COG0096 Ribosomal protein S8; InterPro IPR000630; KEGG: chy:CHY_2295 30S ribosomal protein S8; PFAM: Ribosomal protein S8; SPTR: 30S ribosomal protein S8; IMG reference gene:2504586958; PFAM: Ribosomal protein S8 YP_004413893.1 COGs: COG0199 Ribosomal protein S14; InterPro IPR001209; KEGG: afn:Acfer_1916 ribosomal protein S14; PFAM: Ribosomal protein S14; SPTR: Ribosomal protein S14p/S29e; IMG reference gene:2504586959; PFAM: Ribosomal protein S14p/S29e YP_004413894.1 COGs: COG0094 Ribosomal protein L5; InterPro IPR002132; KEGG: gct:GC56T3_0118 ribosomal protein L5; PFAM: Ribosomal protein L5; SPTR: 50S ribosomal protein L5; IMG reference gene:2504586960; PFAM: ribosomal L5P family C-terminus; Ribosomal protein L5 YP_004413895.1 COGs: COG0198 Ribosomal protein L24; InterPro IPR005824:IPR003256; KEGG: afn:Acfer_1918 ribosomal protein L24; PFAM: KOW; SMART: KOW; SPTR: 50S ribosomal protein L24; TIGRFAM: Ribosomal protein L24; IMG reference gene:2504586961; PFAM: KOW motif; TIGRFAM: ribosomal protein L24, bacterial/organelle YP_004413896.1 COGs: COG0093 Ribosomal protein L14; InterPro IPR000218:IPR005745; KEGG: afn:Acfer_1919 ribosomal protein L14; PFAM: Ribosomal protein L14b/L23e; SPTR: 50S ribosomal protein L14; TIGRFAM: Ribosomal protein L14, bacterial-type; IMG reference gene:2504586962; PFAM: Ribosomal protein L14p/L23e; TIGRFAM: ribosomal protein L14, bacterial/organelle YP_004413897.1 COGs: COG0186 Ribosomal protein S17; InterPro IPR019984:IPR000266; KEGG: bts:Btus_0162 30S ribosomal protein S17; PFAM: Ribosomal protein S17; SPTR: 30S ribosomal protein S17; TIGRFAM: Ribosomal protein S17, bacterial-type; IMG reference gene:2504586963; PFAM: Ribosomal protein S17; TIGRFAM: 30S ribosomal protein S17 YP_004413898.1 COGs: COG0255 Ribosomal protein L29; InterPro IPR001854; KEGG: vpr:Vpar_1486 ribosomal protein L29; PFAM: Ribosomal protein L29; SPTR: 50S ribosomal protein L29; TIGRFAM: Ribosomal protein L29; IMG reference gene:2504586964; PFAM: Ribosomal L29 protein; TIGRFAM: ribosomal protein L29 YP_004413899.1 COGs: COG0197 Ribosomal protein L16/L10E; InterPro IPR000114:IPR016180; KEGG: vpr:Vpar_1487 ribosomal protein L16; PFAM: Ribosomal protein L10e/L16; SPTR: 50S ribosomal protein L16; TIGRFAM: Ribosomal protein L16; IMG reference gene:2504586965; PFAM: Ribosomal protein L16p/L10e; TIGRFAM: ribosomal protein L16, bacterial/organelle YP_004413900.1 COGs: COG0092 Ribosomal protein S3; InterProIPR008282:IPR004044:IPR001351:IPR004087:IPR 005704; KEGG: vpr:Vpar_1488 ribosomal protein S3; PFAM: Ribosomal protein S3, C-terminal; Ribosomal protein S3, N-terminal; K Homology, type 2; SMART: K Homology; SPTR: 30S ribosomal protein S3; TIGRFAM: Ribosomal protein S3, bacterial; IMG reference gene:2504586966; PFAM: KH domain; Ribosomal protein S3, C-terminal domain; Ribosomal protein S3, N-terminal domain; TIGRFAM: ribosomal protein S3, bacterial type YP_004413901.1 COGs: COG0091 Ribosomal protein L22; InterPro IPR001063:IPR005727; KEGG: vpr:Vpar_1489 ribosomal protein L22; PFAM: Ribosomal protein L22/L17; SPTR: 50S ribosomal protein L22; TIGRFAM: Ribosomal protein L22, bacterial-type; IMG reference gene:2504586967; PFAM: Ribosomal protein L22p/L17e; TIGRFAM: ribosomal protein L22, bacterial type YP_004413902.1 COGs: COG0185 Ribosomal protein S19; InterPro IPR002222:IPR005732; KEGG: cce:Ccel_0762 30S ribosomal protein S19; PFAM: Ribosomal protein S19/S15; SPTR: 30S ribosomal protein S19; TIGRFAM: Ribosomal protein S19, bacterial-type; IMG reference gene:2504586968; PFAM: Ribosomal protein S19; TIGRFAM: ribosomal protein S19, bacterial/organelle YP_004413903.1 COGs: COG0090 Ribosomal protein L2; InterPro IPR022666:IPR022669:IPR005880; KEGG: afn:Acfer_1926 ribosomal protein L2; PFAM: Ribosomal protein L2, C-terminal; Ribosomal Proteins L2, RNA binding domain; SPTR: 50S ribosomal protein L2; TIGRFAM: Ribosomal protein L2, bacterial-type; IMG reference gene:2504586969; PFAM: Ribosomal Proteins L2, RNA binding domain; Ribosomal Proteins L2, C-terminal domain; TIGRFAM: ribosomal protein L2, bacterial/organellar YP_004413904.1 COGs: COG0089 Ribosomal protein L23; InterPro IPR013025; KEGG: vpr:Vpar_1492 ribosomal protein L25/L23; PFAM: Ribosomal protein L25/L23; SPTR: 50S ribosomal protein L23; IMG reference gene:2504586970; PFAM: Ribosomal protein L23 YP_004413905.1 COGs: COG0088 Ribosomal protein L4; InterPro IPR002136; KEGG: bha:BH0135 50S ribosomal protein L4; PFAM: Ribosomal protein L4/L1e; SPTR: 50S ribosomal protein L4; IMG reference gene:2504586971; PFAM: Ribosomal protein L4/L1 family; TIGRFAM: 50S ribosomal protein L4, bacterial/organelle YP_004413906.1 COGs: COG0087 Ribosomal protein L3; InterPro IPR000597:IPR019927; KEGG: vpr:Vpar_1494 ribosomal protein L3; PFAM: Ribosomal protein L3; SPTR: 50S ribosomal protein L3; TIGRFAM: Ribosomal protein L3, bacterial/organelle-type; IMG reference gene:2504586972; PFAM: Ribosomal protein L3; TIGRFAM: 50S ribosomal protein L3, bacterial YP_004413907.1 COGs: COG0051 Ribosomal protein S10; HAMAP: Ribosomal protein S10 subgroup; InterPro IPR005731:IPR001848; KEGG: dhd:Dhaf_0421 30S ribosomal protein S10; PFAM: Ribosomal protein S10; SPTR: 30S ribosomal protein S10; TIGRFAM: Ribosomal protein S10 subgroup; IMG reference gene:2504586973; PFAM: Ribosomal protein S10p/S20e; TIGRFAM: ribosomal protein S10, bacterial/organelle YP_004413908.1 COGs: COG0050 GTPase - translation elongation factors; InterProIPR004160:IPR004541:IPR005225:IPR004161:IPR 000795; KEGG: vpr:Vpar_1514 translation elongation factor Tu; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, C-terminal; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Elongation factor Tu; TIGRFAM: Translation elongation factor EFTu/EF1A, bacterial/organelle; Small GTP-binding protein; IMG reference gene:2504586974; PFAM: Elongation factor Tu domain 2; Elongation factor Tu C-terminal domain; Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; translation elongation factor TU YP_004413909.1 COGs: COG0480 Translation elongation factors (GTPase); InterProIPR000795:IPR004161:IPR005517:IPR000640:IPR 004540:IPR005225; KEGG: afn:Acfer_1932 translation elongation factor G; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, domain IV; Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor G; TIGRFAM: Translation elongation factor EFG/EF2; Small GTP-binding protein; IMG reference gene:2504586975; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; Elongation factor G, domain IV; TIGRFAM: translation elongation factor EF-G; small GTP-binding protein domain YP_004413910.1 COGs: COG0049 Ribosomal protein S7; InterPro IPR000235:IPR005717; KEGG: vpr:Vpar_1498 ribosomal protein S7; PFAM: Ribosomal protein S7; SPTR: 30S ribosomal protein S7; TIGRFAM: Ribosomal protein S7, bacterial-type; IMG reference gene:2504586976; PFAM: Ribosomal protein S7p/S5e; TIGRFAM: ribosomal protein S7, bacterial/organelle YP_004413911.1 COGs: COG0048 Ribosomal protein S12; InterPro IPR006032:IPR005679; KEGG: tjr:TherJR_0291 ribosomal protein S12; PFAM: Ribosomal protein S12/S23; SPTR: 30S ribosomal protein S12; TIGRFAM: Ribosomal protein S12, bacteria; IMG reference gene:2504586977; PFAM: Ribosomal protein S12; TIGRFAM: ribosomal protein S12, bacterial/organelle YP_004413912.1 InterPro IPR004038; KEGG: mta:Moth_2466 50S ribosomal protein L7AE; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45; SPTR: Ribosomal protein L7ae family protein; IMG reference gene:2504586978; PFAM: Ribosomal protein L7Ae/L30e/S12e/Gadd45 family YP_004413913.1 InterPro IPR010106; KEGG: cbt:CLH_2455 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504586979; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413914.1 InterPro IPR019267; KEGG: vpr:Vpar_1811 hypothetical protein; PFAM: Protein of unknown function DUF2276; SPTR: Putative CRISPR-associated protein; IMG reference gene:2504586980; PFAM: Uncharacterized conserved protein (DUF2276); TIGRFAM: CRISPR-associated endoribonuclease Cas6 YP_004413915.1 COGs: COG0622 phosphoesterase; InterPro IPR000979:IPR004843; KEGG: tpd:Teth39_1576 phosphodiesterase; PFAM: Metallo-dependent phosphatase; SPTR: Phosphodiesterase, MJ0936 family; TIGRFAM: Phosphodiesterase MJ0936; IMG reference gene:2504586981; PFAM: Calcineurin-like phosphoesterase; TIGRFAM: phosphoesterase, MJ0936 family YP_004413916.1 COGs: COG0054 Riboflavin synthase beta-chain; InterPro IPR002180; KEGG: gym:GYMC10_2153 6,7-dimethyl-8-ribityllumazine synthase; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; SPTR: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase; IMG reference gene:2504586982; PFAM: 6,7-dimethyl-8-ribityllumazine synthase; TIGRFAM: 6,7-dimethyl-8-ribityllumazine synthase YP_004413917.1 InterPro IPR002818; KEGG: bfr:BF3075 hypothetical protein; PFAM: ThiJ/PfpI; SPTR: DJ-1/PfpI family protein; manually curated; IMG reference gene:2504586983; PFAM: DJ-1/PfpI family YP_004413918.1 COGs: COG0108 3 4-dihydroxy-2-butanone 4-phosphate synthase; InterPro IPR000926:IPR000422; KEGG: afn:Acfer_0355 3,4-dihydroxy-2-butanone 4-phosphate synthase; PFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; SPTR: Riboflavin biosynthesis protein ribBA; TIGRFAM: 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB; GTP cyclohydrolase II, RibA; IMG reference gene:2504586984; PFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase; TIGRFAM: GTP cyclohydrolase II; 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_004413919.1 COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: cth:Cthe_0105 riboflavin synthase subunit alpha; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; IMG reference gene:2504586985; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit YP_004413920.1 COGs: COG1985 Pyrimidine reductase riboflavin biosynthesis; InterProIPR002734:IPR006401:IPR004794:IPR002125:IPR 011549; KEGG: drm:Dred_2093 riboflavin biosynthesis protein RibD; PFAM: Bacterial bifunctional deaminase-reductase, C-terminal; CMP/dCMP deaminase, zinc-binding; PRIAM: Diaminohydroxyphosphoribosylaminopyrimidine deaminase., 5-amino-6-(5-phosphoribosylamino)uracil reductase; SPTR: Riboflavin biosynthesis protein RibD; TIGRFAM: Riboflavin biosynthesis protein RibD; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal; Riboflavin-specific deaminase, C-terminal; IMG reference gene:2504586986; PFAM: RibD C-terminal domain; Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: riboflavin-specific deaminase C-terminal domain; 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1'-reductase, archaeal; riboflavin biosynthesis protein RibD YP_004413921.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR002477:IPR000064; KEGG: afn:Acfer_0818 NLP/P60 protein; PFAM: NLP/P60; Peptidoglycan binding-like; SPTR: Endopeptidase, cell wall lytic activity; IMG reference gene:2504586987; PFAM: NlpC/P60 family; Putative peptidoglycan binding domain YP_004413922.1 COGs: COG0327 conserved hypothetical protein; InterPro IPR002678; KEGG: dau:Daud_0497 hypothetical protein; PFAM: NGG1p interacting factor 3, NIF3; SPTR: Putative NIF3 family protein family protein; TIGRFAM: NGG1p interacting factor 3, NIF3; IMG reference gene:2504586989; PFAM: NIF3 (NGG1p interacting factor 3); TIGRFAM: dinuclear metal center protein, YbgI/SA1388 family YP_004413923.1 COGs: COG2384 SAM-dependent methyltransferase; InterPro IPR006901; KEGG: pth:PTH_0913 SAM-dependent methyltransferase; PFAM: Protein of unknown function DUF633; SPTR: SAM-dependent methyltransferase; IMG reference gene:2504586990; PFAM: Family of unknown function (DUF633) YP_004413924.1 COGs: COG0568 DNA-directed RNA polymerase sigma subunit (sigma70/sigma32); InterProIPR007624:IPR007127:IPR014284:IPR007627:IPR 007630:IPR012760:IPR009042; KEGG: hmo:HM1_1995 RNA polymerase sigma factor RpoD; PFAM: RNA polymerase sigma-70 region 3; RNA polymerase sigma factor 70, region 1.1; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 1.2; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor RpoD, C-terminal; RNA polymerase sigma-70; IMG reference gene:2504586991; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 factor, region 1.1; Sigma-70 region 2; Sigma-70 factor, region 1.2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family; RNA polymerase sigma factor RpoD, C-terminal domain YP_004413925.1 COGs: COG0358 DNA primase; InterPro IPR002694:IPR013264:IPR006171:IPR006295; KEGG: afn:Acfer_1782 DNA primase; PFAM: DNA primase, catalytic core, N-terminal; Zinc finger, CHC2-type; Toprim domain; SPTR: DNA primase; TIGRFAM: DNA primase, DnaG; IMG reference gene:2504586992; PFAM: Toprim domain; DNA primase catalytic core, N-terminal domain; CHC2 zinc finger; TIGRFAM: DNA primase, catalytic core YP_004413926.1 COGs: COG0232 dGTP triphosphohydrolase; InterPro IPR003607:IPR006261:IPR006674; KEGG: dhd:Dhaf_4219 deoxyguanosinetriphosphate triphosphohydrolase-like protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative deoxyguanosinetriphosphate triphosphohydrolase; TIGRFAM: Deoxyguanosinetriphosphate triphosphohydrolase; IMG reference gene:2504586993; PFAM: HD domain; TIGRFAM: deoxyguanosinetriphosphate triphosphohydrolase, putative YP_004413927.1 InterPro IPR005653; PFAM: Organic solvent tolerance-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504586994; PFAM: OstA-like protein YP_004413928.1 COGs: COG1808 membrane protein; InterPro IPR005240; KEGG: bcj:BCAS0106 hypothetical protein; PFAM: Protein of unknown function DUF389; SPTR: Putative membrane protein; IMG reference gene:2504586995; PFAM: Domain of unknown function (DUF389); TIGRFAM: uncharacterized hydrophobic domain YP_004413929.1 COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926:IPR006654; KEGG: cbk:CLL_A1973 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 2; TIGRFAM: Tryptophan synthase, beta chain; IMG reference gene:2504586996; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004413930.1 COGs: COG4783 Putative Zn-dependent protease contains TPR repeats; InterPro IPR001915; KEGG: afn:Acfer_0326 peptidase M48 Ste24p; PFAM: Peptidase M48; SPTR: Peptidase family M48 family protein; IMG reference gene:2504586997; PFAM: Peptidase family M48 YP_004413931.1 KEGG: hor:Hore_18030 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504586998 YP_004413932.1 COGs: COG0698 Ribose 5-phosphate isomerase RpiB; InterPro IPR003500; KEGG: sth:STH77 ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase; SPTR: Ribose 5-phosphate isomerase B; TIGRFAM: Ribose/galactose isomerase; IMG reference gene:2504587001; PFAM: Ribose/Galactose Isomerase; TIGRFAM: sugar-phosphate isomerases, RpiB/LacA/LacB family YP_004413933.1 HAMAP: Ribosomal protein S20; InterPro IPR002583; KEGG: vpr:Vpar_0777 ribosomal protein S20; PFAM: Ribosomal protein S20; SPTR: 30S ribosomal protein S20; TIGRFAM: Ribosomal protein S20; IMG reference gene:2504587002; PFAM: Ribosomal protein S20; TIGRFAM: ribosomal protein S20 YP_004413934.1 KEGG: afn:Acfer_1536 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587003; PFAM: Glutaredoxin YP_004413935.1 COGs: COG4260 Putative virion core protein (lumpy skin disease virus); KEGG: afn:Acfer_0836 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587004 YP_004413936.1 KEGG: afn:Acfer_0837 hypothetical protein; SPTR: Zinc finger domain, LSD1 subclass subfamily; IMG reference gene:2504587005 YP_004413937.1 COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: afn:Acfer_0838 protein of unknown function DUF477; PFAM: Protein of unknown function DUF477; SPTR: Putative uncharacterized protein; IMG reference gene:2504587006; PFAM: Domain of unknown function (DUF477) YP_004413938.1 COGs: COG1408 phosphohydrolase; InterPro IPR004843; KEGG: hmo:HM1_0407 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Ser/Thr protein phosphatase family protein; IMG reference gene:2504587007; PFAM: Calcineurin-like phosphoesterase YP_004413939.1 COGs: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; InterPro IPR002023; KEGG: tme:Tmel_0492 NADH dehydrogenase (ubiquinone), 24 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 24kDa subunit; SPTR: NADH-quinone oxidoreductase, E subunit; IMG reference gene:2504587008; PFAM: Respiratory-chain NADH dehydrogenase 24 Kd subunit YP_004413940.1 COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538:IPR019575:IPR019554; KEGG: dhd:Dhaf_1397 NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; Soluble ligand binding domain; PRIAM: NADH dehydrogenase (quinone); SMART: NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; SPTR: Protein HymB; IMG reference gene:2504587009; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain YP_004413941.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR003149:IPR019574:IPR004108:IPR013352; KEGG: adg:Adeg_1783 hydrogenase, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; Iron hydrogenase, small subunit-like; PRIAM: Ferredoxin hydrogenase; SMART: Iron hydrogenase, small subunit-like; NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding; SPTR: Ferredoxin hydrogenase; TIGRFAM: Iron hydrogenase, subset; IMG reference gene:2504587010; PFAM: Iron only hydrogenase large subunit, C-terminal domain; NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Iron hydrogenase small subunit; TIGRFAM: hydrogenase, Fe-only YP_004413942.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: pdi:BDI_3405 hypothetical protein; PFAM: Protein of unknown function DUF1212; SPTR: Putative uncharacterized protein; IMG reference gene:2504587011; PFAM: Protein of unknown function (DUF1212) YP_004413943.1 COGs: COG2966 conserved hypothetical protein; InterPro IPR010619; KEGG: pdi:BDI_3405 hypothetical protein; PFAM: Protein of unknown function DUF1212; SPTR: Putative uncharacterized protein; IMG reference gene:2504587012; PFAM: Protein of unknown function (DUF1212) YP_004413944.1 SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; IMG reference gene:2504587013 YP_004413945.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587014 YP_004413946.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587015 YP_004413947.1 COGs: COG3279 Response regulator of the LytR/AlgR family; InterPro IPR001789:IPR007492; KEGG: elm:ELI_2014 hypothetical protein; PFAM: Signal transduction response regulator, receiver domain; LytTr, DNA-binding domain; SMART: Signal transduction response regulator, receiver domain; LytTr, DNA-binding domain; SPTR: Putative response regulator receiver domain protein; IMG reference gene:2504587016; PFAM: Response regulator receiver domain; LytTr DNA-binding domain YP_004413948.1 InterPro IPR003594; KEGG: afn:Acfer_0033 hypothetical protein; PFAM: ATPase-like, ATP-binding domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504587017 YP_004413949.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587018 YP_004413950.1 COGs: COG0074 Succinyl-CoA synthetase alpha subunit; InterPro IPR005810:IPR003781:IPR005811; KEGG: lsp:Bsph_1538 succinyl-CoA synthetase subunit alpha; PFAM: CoA-binding; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SMART: CoA-binding; SPTR: Succinyl-CoA ligase [ADP-forming] subunit alpha; TIGRFAM: Succinyl-CoA ligase, alpha subunit; IMG reference gene:2504587019; PFAM: CoA binding domain; CoA-ligase; TIGRFAM: succinyl-CoA synthetase, alpha subunit YP_004413951.1 COGs: COG0045 Succinyl-CoA synthetase beta subunit; HAMAP: Succinyl-CoA synthetase, beta subunit; InterPro IPR013650:IPR005811:IPR005809; KEGG: gmc:GY4MC1_2701 succinyl-CoA synthetase, beta subunit; PFAM: ATP-grasp fold, succinyl-CoA synthetase-type; ATP-citrate lyase/succinyl-CoA ligase; PRIAM: Succinate--CoA ligase (ADP-forming); SPTR: Succinyl-CoA ligase [ADP-forming] subunit beta; TIGRFAM: Succinyl-CoA synthetase, beta subunit; IMG reference gene:2504587020; PFAM: CoA-ligase; ATP-grasp domain; TIGRFAM: succinyl-CoA synthetase, beta subunit YP_004413952.1 COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR001347:IPR000644:IPR004800; KEGG: afn:Acfer_1681 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; PRIAM: Arabinose-5-phosphate isomerase; SMART: Cystathionine beta-synthase, core; SPTR: Arabinose 5-phosphate isomerase; TIGRFAM: KpsF/GutQ; IMG reference gene:2504587021; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein YP_004413953.1 COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: elm:ELI_0465 putative carbon starvation protein CstA; PFAM: Carbon starvation protein CstA; SPTR: Carbon starvation protein CstA; IMG reference gene:2504587022; PFAM: Carbon starvation protein CstA YP_004413954.1 SPTR: Putative periplasmic binding protein/LacI transcriptional regulator; IMG reference gene:2504587023 YP_004413955.1 InterPro IPR002917; KEGG: pna:Pnap_2751 GTP-binding protein, HSR1-related; PFAM: GTP-binding protein, HSR1-related; SPTR: Putative GTP-binding protein; IMG reference gene:2504587024; PFAM: GTPase of unknown function YP_004413956.1 COGs: COG1032 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: cpy:Cphy_3574 radical SAM domain-containing protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative radical SAM domain protein; IMG reference gene:2504587025; PFAM: Radical SAM superfamily YP_004413957.1 COGs: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); InterPro IPR007197:IPR006638; KEGG: mst:Msp_0612 arylsulfatase regulatory protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative radical SAM domain protein; IMG reference gene:2504587026; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM additional 4Fe4S-binding domain YP_004413958.1 KEGG: pna:Pnap_2750 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587027 YP_004413959.1 SPTR: Putative geminin; IMG reference gene:2504587028 YP_004413960.1 InterPro IPR006703; KEGG: hse:Hsero_1315 hypothetical protein; PFAM: AIG1; SPTR: Putative uncharacterized protein; IMG reference gene:2504587029; PFAM: AIG1 family YP_004413961.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587030 YP_004413962.1 InterPro IPR001387; KEGG: cyh:Cyan8802_3920 transcriptional regulator, XRE family; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; manually curated; IMG reference gene:2504587031; PFAM: Helix-turn-helix YP_004413963.1 COGs: COG0515 Serine/threonine protein kinase; InterPro IPR017442; KEGG: lwe:lwe0588 protein kinase domain-containing protein; PFAM: Serine/threonine-protein kinase-like domain; SPTR: Protein kinase domain protein; IMG reference gene:2504587032; PFAM: Protein kinase domain YP_004413964.1 KEGG: ere:EUBREC_0928 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587033; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413965.1 InterPro IPR001387; KEGG: lsg:lse_0528 hypothetical protein; SMART: Helix-turn-helix type 3; SPTR: Putative uncharacterized protein; IMG reference gene:2504587034 YP_004413966.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089:IPR003660; KEGG: cbl:CLK_0094 methyl-accepting chemotaxis protein; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504587035; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004413967.1 COGs: COG0577 ABC-type antimicrobial peptide transport system permease component; InterPro IPR003838; KEGG: afn:Acfer_0232 protein of unknown function DUF214; PFAM: Domain of unknown function DUF214, ABC transporter permease; SPTR: Macrolide export ATP-binding/permease protein MacB; IMG reference gene:2504587036; PFAM: Predicted permease YP_004413968.1 COGs: COG1136 ABC-type antimicrobial peptide transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: vpr:Vpar_1071 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Macrolide export ATP-binding/permease protein MacB; IMG reference gene:2504587037; PFAM: ABC transporter YP_004413969.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: vpr:Vpar_1072 efflux transporter, RND family, MFP subunit; SPTR: Putative periplasmic component of efflux system; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504587038; TIGRFAM: RND family efflux transporter, MFP subunit YP_004413970.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: afn:Acfer_1698 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Putative outer membrane efflux protein; IMG reference gene:2504587039; PFAM: Outer membrane efflux protein YP_004413971.1 COGs: COG0514 Superfamily II DNA helicase; InterProIPR011545:IPR001650:IPR006293:IPR004589:IPR 002121:IPR018982:IPR014001; KEGG: dsy:DSY1775 hypothetical protein; PFAM: RQC domain; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase/RNase D C-terminal, HRDC domain; SMART: RQC domain; Helicase/RNase D C-terminal, HRDC domain; Helicase, C-terminal; DEAD-like helicase, N-terminal; SPTR: ATP-dependent DNA helicase RecQ; TIGRFAM: DNA helicase, ATP-dependent, RecQ type, bacterial; DNA helicase, ATP-dependent, RecQ type; IMG reference gene:2504587040; PFAM: Helicase conserved C-terminal domain; RQC domain; HRDC domain; DEAD/DEAH box helicase; TIGRFAM: ATP-dependent DNA helicase RecQ; ATP-dependent DNA helicase, RecQ family YP_004413972.1 InterPro IPR011701; KEGG: pfl:PFL_4038 transporter, putative; PFAM: Major facilitator superfamily MFS-1; SPTR: Putative transporter; IMG reference gene:2504587041; PFAM: Major Facilitator Superfamily YP_004413973.1 InterPro IPR021729; KEGG: bpb:bpr_III072 hypothetical protein; PFAM: Domain of unknown function DUF3298; SPTR: Putative uncharacterized protein; IMG reference gene:2504587042; PFAM: Protein of unknown function (DUF3298) YP_004413974.1 COGs: COG2233 Xanthine/uracil permease; InterPro IPR006042:IPR006043; KEGG: drm:Dred_1317 uracil transporter; PFAM: Xanthine/uracil/vitamin C permease; SPTR: Uracil permease; TIGRFAM: Xanthine/uracil permease; IMG reference gene:2504587043; PFAM: Permease family; TIGRFAM: uracil-xanthine permease YP_004413975.1 COGs: COG0733 Na+-dependent transporter of the SNF family; InterPro IPR000175; KEGG: ere:EUBREC_1419 Na+-dependent transporters of the SNF family; PFAM: Sodium:neurotransmitter symporter; SPTR: Transporter; IMG reference gene:2504587044; PFAM: Sodium:neurotransmitter symporter family YP_004413976.1 COGs: COG0663 Carbonic anhydrase/acetyltransferase isoleucine patch superfamily; InterPro IPR001451; KEGG: ipo:Ilyop_0999 ferripyochelin binding protein (fbp); SPTR: Hexapeptide transferase family protein; IMG reference gene:2504587045 YP_004413977.1 KEGG: ere:EUBREC_2192 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587046; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004413978.1 COGs: COG1381 Recombinational DNA repair protein (RecF pathway); InterPro IPR003717:IPR022572; KEGG: afn:Acfer_0624 DNA repair protein RecO; PFAM: DNA replication/recombination mediator RecO, N-terminal; Recombination protein O, RecO; SPTR: DNA repair protein recO; TIGRFAM: Recombination protein O, RecO; IMG reference gene:2504587048; PFAM: Recombination protein O C terminal; Recombination protein O N terminal; TIGRFAM: DNA repair protein RecO YP_004413979.1 COGs: COG2928 conserved hypothetical protein; InterPro IPR007462; KEGG: mep:MPQ_2397 hypothetical protein; PFAM: Protein of unknown function DUF502; SPTR: Putative integral membrane protein; IMG reference gene:2504587049; PFAM: Protein of unknown function (DUF502) YP_004413980.1 COGs: COG1159 GTPase; InterPro IPR004044:IPR002917:IPR005662:IPR005225; KEGG: vpr:Vpar_0990 GTP-binding protein Era; PFAM: GTP-binding protein, HSR1-related; K Homology, type 2; SPTR: GTP-binding protein era homolog; TIGRFAM: GTP-binding protein Era; Small GTP-binding protein; IMG reference gene:2504587050; PFAM: KH domain; GTPase of unknown function; TIGRFAM: GTP-binding protein Era; small GTP-binding protein domain YP_004413981.1 COGs: COG0319 metal-dependent hydrolase; InterPro IPR002036; KEGG: dsy:DSY3109 hypothetical protein; PFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; SPTR: Putative metalloprotease SELSPUOL_00620; TIGRFAM: Uncharacterised protein family UPF0054, metalloprotease YbeY, predicted; IMG reference gene:2504587051; PFAM: Uncharacterized protein family UPF0054; TIGRFAM: metalloprotein, YbeY/UPF0054 family YP_004413982.1 COGs: COG1702 Phosphate starvation-inducible protein PhoH predicted ATPase; InterPro IPR003714; KEGG: afn:Acfer_0619 PhoH family protein; PFAM: PhoH-like protein; SPTR: PhoH family protein; IMG reference gene:2504587052; PFAM: PhoH-like protein YP_004413983.1 COGs: COG0502 Biotin synthase; InterPro IPR007197:IPR002684:IPR010722:IPR006638; KEGG: afn:Acfer_1537 biotin synthase; PFAM: Biotin/thiamin synthesis-associated protein; Radical SAM; PRIAM: Biotin synthase; SMART: Elongator protein 3/MiaB/NifB; Biotin/thiamin synthesis-associated protein; SPTR: Biotin synthase; TIGRFAM: Biotin synthase; IMG reference gene:2504587053; PFAM: Radical SAM superfamily; Biotin and Thiamin Synthesis associated domain; TIGRFAM: biotin synthetase YP_004413984.1 COGs: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase; InterPro IPR013027:IPR001327; KEGG: cpy:Cphy_3412 putative oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Glutamate synthase (NADPH); SPTR: Glutamate synthase, homotetrameric; IMG reference gene:2504587054; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004413985.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR019264:IPR003740; KEGG: cbi:CLJ_B1141 hypothetical protein; PFAM: Domain of unknown function DUF2179; Protein of unknown function DUF161; SPTR: Transporter; IMG reference gene:2504587055; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004413986.1 COGs: COG0463 Glycosyltransferase involved in cell wall biogenesis; InterPro IPR001173; KEGG: vpr:Vpar_1183 glycosyl transferase family 2; PFAM: Glycosyl transferase, family 2; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504587056; PFAM: Glycosyl transferase family 2 YP_004413987.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003661:IPR003594; KEGG: afn:Acfer_0937 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; ATPase-like, ATP-binding domain; SPTR: Sensor histidine kinase; IMG reference gene:2504587057; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004413988.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: afn:Acfer_0936 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: DNA-binding response regulator DltR; IMG reference gene:2504587058; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004413989.1 COGs: COG2357 conserved hypothetical protein; InterPro IPR007685; KEGG: smc:SmuNN2025_1101 hypothetical protein; PFAM: RelA/SpoT; SMART: RelA/SpoT; SPTR: RelA/SpoT domain protein; IMG reference gene:2504587059; PFAM: Region found in RelA / SpoT proteins YP_004413990.1 COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR001182; KEGG: vpr:Vpar_0347 cell cycle protein; PFAM: Cell cycle protein; SPTR: Cell division protein FtsW; IMG reference gene:2504587060; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW YP_004413991.1 COGs: COG0220 S-adenosylmethionine-dependent methyltransferase; HAMAP: tRNA (guanine-N-7) methyltransferase; InterPro IPR003358; KEGG: vpr:Vpar_0346 tRNA (guanine-N(7)-)-methyltransferase; PFAM: tRNA (guanine-N-7) methyltransferase; SPTR: tRNA (guanine-N(7)-)-methyltransferase; TIGRFAM: tRNA (guanine-N-7) methyltransferase; IMG reference gene:2504587061; PFAM: Putative methyltransferase; TIGRFAM: tRNA (guanine-N(7)-)-methyltransferase YP_004413992.1 COGs: COG3829 Transcriptional regulator containing PAS AAA-type ATPase and DNA-binding domains; InterPro IPR002078:IPR003593:IPR002197; KEGG: afn:Acfer_0116 sigma54 specific transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Helix-turn-helix, Fis-type; SMART: ATPase, AAA+ type, core; SPTR: Two component, sigma54 specific, transcriptional regulator, Fis family; IMG reference gene:2504587062; PFAM: Bacterial regulatory protein, Fis family; Sigma-54 interaction domain YP_004413993.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587063 YP_004413994.1 COGs: COG2865 transcriptional regulator protein; InterPro IPR007421:IPR000835; KEGG: fsu:Fisuc_1186 putative transcriptional regulator; PFAM: ATPase, AAA-4; HTH transcriptional regulator, MarR; SPTR: Divergent AAA domain protein; IMG reference gene:2504587064; PFAM: Divergent AAA domain; MarR family YP_004413995.1 KEGG: ere:EUBREC_1097 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587065 YP_004413996.1 COGs: COG2109 ATP:corrinoid adenosyltransferase; InterPro IPR003724; KEGG: vpr:Vpar_1843 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; PFAM: Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR; SPTR: Cob(I)yrinic acid a,c-diamide adenosyltransferase; IMG reference gene:2504587066; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP; TIGRFAM: cob(I)alamin adenosyltransferase YP_004413997.1 COGs: COG0780 Enzyme related to GTP cyclohydrolase I; HAMAP: Nitrile oxidoreductase, NADPH-dependent, QueF; InterPro IPR020602:IPR016856; KEGG: bwe:BcerKBAB4_1259 7-cyano-7-deazaguanine reductase; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase; PRIAM: PreQ(1) synthase; SPTR: NADPH-dependent 7-cyano-7-deazaguanine reductase; TIGRFAM: Nitrile oxidoreductase, NADPH-dependent, QueF; IMG reference gene:2504587067; PFAM: GTP cyclohydrolase I; TIGRFAM: 7-cyano-7-deazaguanine reductase YP_004413998.1 COGs: COG2200 FOG: EAL domain; InterPro IPR000160:IPR001633:IPR001610:IPR013655; KEGG: elm:ELI_1550 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAS fold-3; SMART: Diguanylate phosphodiesterase, EAL domain; Diguanylate cyclase, predicted; PAC motif; SPTR: Putative pas:ggdef protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504587068; PFAM: EAL domain; GGDEF domain; PAS fold; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004413999.1 COGs: COG4666 TRAP-type uncharacterized transport system fused permease components; InterPro IPR011853:IPR010656; KEGG: drm:Dred_3211 TRAP transporter, 4TM/12TM fusion protein; PFAM: TRAP C4-dicarboxylate transport system permease DctM subunit; SPTR: TRAP transporter, 4TM/12TM fusion protein; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein; IMG reference gene:2504587069; PFAM: DctM-like transporters; TIGRFAM: TRAP transporter, 4TM/12TM fusion protein YP_004414000.1 InterPro IPR015001; KEGG: drm:Dred_3212 hypothetical protein; PFAM: Protein of unknown function DUF1850; SPTR: Putative uncharacterized protein; IMG reference gene:2504587070; PFAM: Domain of unknown function (DUF1850) YP_004414001.1 COGs: COG2358 TRAP-type uncharacterized transport system periplasmic component; InterPro IPR011852:IPR015168; KEGG: drm:Dred_3213 TRAP transporter solute receptor TAXI family protein; SPTR: TRAP transporter solute receptor, TAXI family; TIGRFAM: TRAP transporter solute receptor, TAXI family; IMG reference gene:2504587071; PFAM: NMT1/THI5 like; TIGRFAM: TRAP transporter solute receptor, TAXI family YP_004414002.1 COGs: COG1179 Dinucleotide-utilizing protein involved in molybdopterin and thiamine biosynthesis family 1; InterPro IPR000594; KEGG: thx:Thet_1429 UBA/ThiF-type NAD/FAD-binding protein; PFAM: UBA/THIF-type NAD/FAD binding fold; SPTR: Hydrogenase accessory protein HypB; IMG reference gene:2504587072; PFAM: ThiF family YP_004414003.1 COGs: COG0206 Cell division GTPase; InterPro IPR003008:IPR000158:IPR018316; KEGG: tmt:Tmath_1467 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; SMART: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal; IMG reference gene:2504587073; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004414004.1 InterPro IPR000620; KEGG: pjd:Pjdr2_0615 protein of unknown function DUF6 transmembrane; PFAM: Drug/metabolite transporter; SPTR: Putative membrane protein; IMG reference gene:2504587074; PFAM: EamA-like transporter family YP_004414005.1 COGs: COG4866 conserved hypothetical protein; KEGG: vpr:Vpar_1640 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587075; PFAM: Uncharacterized conserved protein (DUF2156) YP_004414006.1 COGs: COG1607 Acyl-CoA hydrolase; InterPro IPR006683; KEGG: msl:Msil_2092 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family protein; IMG reference gene:2504587076; PFAM: Thioesterase superfamily YP_004414007.1 COGs: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase synthetase domain; InterPro IPR010918:IPR010141; KEGG: tjr:TherJR_0822 phosphoribosylformylglycinamidine synthase; PFAM: AIR synthase-related protein, C-terminal; PRIAM: Phosphoribosylformylglycinamidine synthase; SPTR: Phosphoribosylformylglycinamidine synthase; TIGRFAM: Phosphoribosylformylglycinamidine synthase, FGAM; IMG reference gene:2504587077; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: phosphoribosylformylglycinamidine synthase, clade II YP_004414008.1 COGs: COG2731 Beta-galactosidase beta subunit; InterPro IPR004375; KEGG: eum:ECUMN_4089 hypothetical protein; PFAM: Conserved hypothetical protein CHP00022; SPTR: Protein YiaL; TIGRFAM: Conserved hypothetical protein CHP00022; IMG reference gene:2504587078; PFAM: Domain of unknown function (DUF386); TIGRFAM: uncharacterized protein, YhcH/YjgK/YiaL family YP_004414009.1 COGs: COG1522 Transcriptional regulators; InterPro IPR019887:IPR019888; KEGG: tjr:TherJR_2931 transcriptional regulator, AsnC family; PFAM: Transcription regulator AsnC-type, C-terminal; SMART: Transcription regulator AsnC-type; SPTR: Transcriptional regulator, AsnC family; IMG reference gene:2504587079; PFAM: AsnC family YP_004414010.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: drm:Dred_3192 aminotransferase, class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Aspartate transaminase; SPTR: Aspartate transaminase; IMG reference gene:2504587080; PFAM: Aminotransferase class I and II YP_004414011.1 COGs: COG0628 permease; InterPro IPR002549; KEGG: cki:Calkr_1317 hypothetical protein; PFAM: Uncharacterised protein family UPF0118; SPTR: Putative uncharacterized protein; IMG reference gene:2504587081; PFAM: Domain of unknown function DUF20 YP_004414012.1 COGs: COG0751 Glycyl-tRNA synthetase beta subunit; InterPro IPR015944:IPR008909:IPR002311; KEGG: afn:Acfer_1779 glycyl-tRNA synthetase, beta subunit; PFAM: Glycyl-tRNA synthetase, class IIc, beta subunit, N-terminal; DALR anticodon binding; PRIAM: Glycine--tRNA ligase; SMART: DALR anticodon binding; SPTR: Glycyl-tRNA synthetase beta subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, beta subunit; IMG reference gene:2504587082; PFAM: Glycyl-tRNA synthetase beta subunit; DALR anticodon binding domain; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, beta subunit YP_004414013.1 COGs: COG0752 Glycyl-tRNA synthetase alpha subunit; HAMAP: Glycyl-tRNA synthetase, class IIc, alpha subunit; InterPro IPR002310; KEGG: afn:Acfer_1780 glycyl-tRNA synthetase, alpha subunit; PFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit; PRIAM: Glycine--tRNA ligase; SPTR: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: Glycyl-tRNA synthetase, class IIc, alpha subunit; IMG reference gene:2504587083; PFAM: Glycyl-tRNA synthetase alpha subunit; TIGRFAM: glycyl-tRNA synthetase, tetrameric type, alpha subunit YP_004414014.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR001140:IPR003439:IPR003593; KEGG: ckr:CKR_1407 hypothetical protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; IMG reference gene:2504587084; PFAM: ABC transporter; ABC transporter transmembrane region YP_004414015.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR003439; KEGG: ckr:CKR_1406 hypothetical protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, permease/ATP-binding protein; IMG reference gene:2504587085; PFAM: ABC transporter transmembrane region; ABC transporter YP_004414016.1 COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterProIPR019456:IPR011895:IPR002880:IPR011766:IPR 019752; KEGG: cbi:CLJ_B2987 pyruvate ferredoxin oxidoreductase; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; PRIAM: Pyruvate dehydrogenase (NADP(+)); SMART: Pyruvate-flavodoxin oxidoreductase, EKR domain; SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavodoxin oxidoreductase; IMG reference gene:2504587086; PFAM: Domain of unknown function; domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; TIGRFAM: pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric YP_004414017.1 InterPro IPR001087; KEGG: afn:Acfer_0534 hypothetical protein; PFAM: Lipase, GDSL; SPTR: Putative lipolytic enzyme, G-D-S-L; IMG reference gene:2504587087 YP_004414018.1 COGs: COG0426 flavoprotein; InterPro IPR008254:IPR001279; KEGG: cpy:Cphy_0262 beta-lactamase domain-containing protein; PFAM: Beta-lactamase-like; Flavodoxin/nitric oxide synthase; SMART: Beta-lactamase-like; SPTR: Rubredoxin-oxygen oxidoreductase; IMG reference gene:2504587088; PFAM: Metallo-beta-lactamase superfamily; Flavodoxin YP_004414019.1 COGs: COG1883 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase beta subunit; InterPro IPR005661; KEGG: vpr:Vpar_1240 sodium ion-translocating decarboxylase, beta subunit; PFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; PRIAM: Glutaconyl-CoA decarboxylase; SPTR: Oxaloacetate decarboxylase, beta subunit; TIGRFAM: Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit; IMG reference gene:2504587089; PFAM: subunit; TIGRFAM: sodium ion-translocating decarboxylase, beta subunit YP_004414020.1 InterPro IPR005899; KEGG: vpr:Vpar_1243 sodium pump decarboxylase, gamma subunit; PFAM: Sodium ion-translocating decarboxylase; SPTR: Glutaconyl-CoA decarboxylase subunit delta; IMG reference gene:2504587090; PFAM: Oxaloacetate decarboxylase, gamma chain YP_004414021.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: ssm:Spirs_0173 sirohydrochlorin cobaltochelatase; PFAM: Anaerobic cobalt chelatase; SPTR: Putative cobalt chelatase; IMG reference gene:2504587091; PFAM: Cobalt chelatase (CbiK) YP_004414022.1 COGs: COG1109 Phosphomannomutase; InterProIPR006352:IPR005846:IPR005845:IPR005844:IPR 005843; KEGG: vpr:Vpar_0295 phosphoglucosamine mutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; PRIAM: Phosphoglucosamine mutase; SPTR: Phosphoglucosamine mutase; TIGRFAM: Phosphoglucosamine mutase; IMG reference gene:2504587092; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I; TIGRFAM: phosphoglucosamine mutase YP_004414023.1 COGs: COG2509 Uncharacterized FAD-dependent dehydrogenase; InterPro IPR003953; KEGG: tjr:TherJR_0378 monooxygenase FAD-binding protein; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Oxidoreductase, FAD-dependent; IMG reference gene:2504587093; PFAM: FAD binding domain YP_004414024.1 COGs: COG4856 conserved hypothetical protein; InterPro IPR012505; KEGG: vpr:Vpar_0293 YbbR family protein; PFAM: YbbR-like; SPTR: Putative uncharacterized protein; IMG reference gene:2504587094; PFAM: YbbR-like protein YP_004414025.1 COGs: COG1624 conserved hypothetical protein; InterPro IPR003390:IPR014046; KEGG: afn:Acfer_0601 protein of unknown function DUF147; PFAM: DNA integrity scanning protein, DisA, N-terminal; SPTR: Putative membrane protein; TIGRFAM: Conserved hypothetical protein CHP00159; IMG reference gene:2504587095; PFAM: DisA bacterial checkpoint controller nucleotide-binding; TIGRFAM: TIGR00159 family protein YP_004414026.1 COGs: COG0063 sugar kinase; InterPro IPR004443:IPR000631; KEGG: tjr:TherJR_0655 carbohydrate kinase, YjeF related protein; PFAM: YjeF-related protein, N-terminal; Uncharacterised protein family, carbohydrate kinase-related; SPTR: YjeF family protein; TIGRFAM: Uncharacterised protein family, carbohydrate kinase-related; YjeF-related protein, N-terminal; IMG reference gene:2504587096; PFAM: Carbohydrate kinase; YjeF-related protein N-terminus; TIGRFAM: yjeF N-terminal region; yjeF C-terminal region, hydroxyethylthiazole kinase-related YP_004414027.1 COGs: COG0736 Phosphopantetheinyl transferase (holo-ACP synthase); HAMAP: Holo-[acyl carrier protein] synthase; InterPro IPR008278:IPR002582:IPR004568; KEGG: afn:Acfer_1629 holo-acyl-carrier-protein synthase; PFAM: 4'-phosphopantetheinyl transferase; SPTR: Holo-[acyl-carrier-protein] synthase; TIGRFAM: Phosphopantethiene-protein transferase; Holo-[acyl carrier protein] synthase; IMG reference gene:2504587097; PFAM: 4'-phosphopantetheinyl transferase superfamily; TIGRFAM: phosphopantethiene--protein transferase domain; holo-[acyl-carrier-protein] synthase YP_004414028.1 COGs: COG1360 Flagellar motor protein; InterPro IPR006665; KEGG: gym:GYMC10_0086 OmpA/MotB domain protein; PFAM: Outer membrane protein, OmpA/MotB, C-terminal; SPTR: Chemotaxis protein MotB; IMG reference gene:2504587098; PFAM: OmpA family YP_004414029.1 COGs: COG1291 Flagellar motor component; InterPro IPR002898; KEGG: bbe:BBR47_08690 flagellar motor protein MotA; PFAM: MotA/TolQ/ExbB proton channel; SPTR: Chemotaxis protein MotA; IMG reference gene:2504587099; PFAM: MotA/TolQ/ExbB proton channel family YP_004414030.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: chy:CHY_0059 LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504587100; PFAM: LysR substrate binding domain; Bacterial regulatory helix-turn-helix protein, lysR family YP_004414031.1 COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839:IPR019942; KEGG: cth:Cthe_3101 L,L-diaminopimelate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase, plant-related; IMG reference gene:2504587101; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase YP_004414032.1 COGs: COG2607 ATPase (AAA+ superfamily); InterPro IPR008533:IPR003593; KEGG: afn:Acfer_0163 protein of unknown function DUF815; PFAM: Domain of unknown function DUF815; SMART: ATPase, AAA+ type, core; SPTR: Type I restriction-modification system, M subunit; IMG reference gene:2504587102; PFAM: Protein of unknown function (DUF815) YP_004414033.1 SPTR: Conotoxin LiCr95; IMG reference gene:2504587103 YP_004414034.1 COGs: COG0192 S-adenosylmethionine synthetase; HAMAP: S-adenosylmethionine synthetase; InterPro IPR022628:IPR022629:IPR022630:IPR002133; KEGG: tjr:TherJR_1806 S-adenosylmethionine synthetase; PFAM: S-adenosylmethionine synthetase, C-terminal; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal; PRIAM: Methionine adenosyltransferase; SPTR: S-adenosylmethionine synthase; TIGRFAM: S-adenosylmethionine synthetase; IMG reference gene:2504587104; PFAM: S-adenosylmethionine synthetase, C-terminal domain; S-adenosylmethionine synthetase, central domain; S-adenosylmethionine synthetase, N-terminal domain; TIGRFAM: S-adenosylmethionine synthetase YP_004414035.1 COGs: COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; InterPro IPR007085:IPR003382:IPR005252; KEGG: aar:Acear_1449 phosphopantothenoylcysteine decarboxylase ;phosphopantothenate-cysteine ligase; PFAM: DNA/pantothenate metabolism flavoprotein, C-terminal; Flavoprotein; PRIAM: Phosphopantothenate--cysteine ligase; SPTR: Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; TIGRFAM: Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; IMG reference gene:2504587105; PFAM: DNA / pantothenate metabolism flavoprotein; Flavoprotein; TIGRFAM: phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase, prokaryotic YP_004414036.1 InterPro IPR006110:IPR003716; KEGG: hmo:HM1_2128 DNA-directed RNA polymerase, omega subunit; PFAM: RNA polymerase, subunit omega/K/RPABC2; SPTR: DNA-directed RNA polymerase subunit omega; TIGRFAM: DNA-directed RNA polymerase, omega subunit; IMG reference gene:2504587106; PFAM: RNA polymerase Rpb6; TIGRFAM: DNA-directed RNA polymerase, omega subunit YP_004414037.1 COGs: COG0194 Guanylate kinase; InterPro IPR008144:IPR017665:IPR008145; KEGG: tpd:Teth39_1324 guanylate kinase; PFAM: Guanylate kinase; PRIAM: Guanylate kinase; SMART: Guanylate kinase/L-type calcium channel; SPTR: Guanylate kinase; TIGRFAM: Guanylate kinase, sub-group; IMG reference gene:2504587107; PFAM: Guanylate kinase; TIGRFAM: guanylate kinase YP_004414038.1 COGs: COG2052 conserved hypothetical protein; InterPro IPR007169; KEGG: pth:PTH_1796 hypothetical protein; PFAM: Uncharacterised protein family UPF0296; SPTR: UPF0296 protein SELSPUOL_00549; IMG reference gene:2504587108; PFAM: Domain of unknown function (DUF370) YP_004414039.1 COGs: COG1561 Uncharacterized stress-induced protein; InterPro IPR013527:IPR005229:IPR013551; KEGG: cth:Cthe_1317 hypothetical protein; PFAM: YicC-like, N-terminal; Domain of unknown function DUF1732; SPTR: YicC protein; TIGRFAM: Conserved hypothetical protein CHP00255; IMG reference gene:2504587109; PFAM: YicC-like family, N-terminal region; Domain of unknown function (DUF1732); TIGRFAM: TIGR00255 family protein YP_004414040.1 COGs: COG4108 Peptide chain release factor RF-3; InterPro IPR000795:IPR004161:IPR004548:IPR005225; KEGG: afn:Acfer_0767 peptide chain release factor 3; PFAM: Protein synthesis factor, GTP-binding; Translation elongation factor EFTu/EF1A, domain 2; SPTR: Peptide chain release factor 3; TIGRFAM: Peptide chain release factor 3; Small GTP-binding protein; IMG reference gene:2504587110; PFAM: Elongation factor Tu GTP binding domain; TIGRFAM: small GTP-binding protein domain; peptide chain release factor 3 YP_004414041.1 COGs: COG0479 Succinate dehydrogenase/fumarate reductase Fe-S protein subunit; InterPro IPR004489; KEGG: bsu:BSU28430 succinate dehydrogenase iron-sulfur subunit; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase, iron-sulfur protein; TIGRFAM: Succinate dehydrogenase/fumarate reductase iron-sulphur protein; IMG reference gene:2504587114; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein YP_004414042.1 COGs: COG1053 Succinate dehydrogenase/fumarate reductase flavoprotein subunit; InterPro IPR004112:IPR011280:IPR003953; KEGG: lsp:Bsph_4053 succinate dehydrogenase flavoprotein subunit; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; Fumarate reductase/succinate dehydrogenase flavoprotein, C-terminal; PRIAM: Succinate dehydrogenase; SPTR: Succinate dehydrogenase, flavoprotein subunit; TIGRFAM: Succinate dehydrogenase/fumarate reductase, flavoprotein subunit, low-GC Gram-positive bacteria; IMG reference gene:2504587115; PFAM: domain; FAD binding domain; TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit, Bacillus subtilis subgroup YP_004414043.1 InterPro IPR011138:IPR000701; KEGG: afl:Aflv_0580 succinate dehydrogenase, cytochrome b subunit; PFAM: Succinate dehydrogenase/Fumarate reductase, transmembrane subunit; SPTR: Succinate dehydrogenase cytochrome B558 subunit; TIGRFAM: Succinate dehydrogenase, cytochrome b558 subunit; IMG reference gene:2504587116; PFAM: Succinate dehydrogenase/Fumarate reductase transmembrane subunit; TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family YP_004414044.1 COGs: COG1838 Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain; InterPro IPR004647; KEGG: vpr:Vpar_1528 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain; IMG reference gene:2504587117; PFAM: Fumarase C-terminus; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region YP_004414045.1 COGs: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I N-terminal domain; InterPro IPR004646; KEGG: vpr:Vpar_1529 hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; PRIAM: Fumarate hydratase; SPTR: Fumarate hydratase, class I; TIGRFAM: Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain; IMG reference gene:2504587118; PFAM: Fumarate hydratase (Fumerase); TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region YP_004414046.1 COGs: COG0622 phosphoesterase; InterPro IPR000979; KEGG: afn:Acfer_0692 phosphodiesterase, MJ0936 family; SPTR: Phosphoesterase family protein; TIGRFAM: Phosphodiesterase MJ0936; IMG reference gene:2504587119; TIGRFAM: phosphoesterase, MJ0936 family YP_004414047.1 COGs: COG0127 Xanthosine triphosphate pyrophosphatase; InterPro IPR002637; KEGG: vpr:Vpar_0436 non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; PFAM: Ham1-like protein; PRIAM: Nucleoside-triphosphatase; SPTR: Nucleoside-triphosphatase; TIGRFAM: Ham1-like protein; IMG reference gene:2504587120; PFAM: Ham1 family; TIGRFAM: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family YP_004414048.1 COGs: COG0689 RNase PH; InterPro IPR015847:IPR001247:IPR002381; KEGG: tit:Thit_0596 ribonuclease PH; PFAM: Exoribonuclease, phosphorolytic domain 1; Exoribonuclease, phosphorolytic domain 2; PRIAM: tRNA nucleotidyltransferase; SPTR: Ribonuclease PH; TIGRFAM: Ribonuclease phosphorolytic, bacterial-type; IMG reference gene:2504587121; PFAM: 3' exoribonuclease family, domain 1; 3' exoribonuclease family, domain 2; TIGRFAM: ribonuclease PH YP_004414049.1 InterPro IPR002847; KEGG: afn:Acfer_0690 protein of unknown function DUF129; PFAM: F420-0 gamma-glutamyl ligase-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504587122; PFAM: F420-0:Gamma-glutamyl ligase YP_004414050.1 KEGG: vpr:Vpar_0431 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587123 YP_004414051.1 COGs: COG0824 thioesterase; InterPro IPR006683:IPR006684; KEGG: vpr:Vpar_0429 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Thioesterase family protein; TIGRFAM: 4-hydroxybenzoyl-CoA thioesterase; IMG reference gene:2504587124; PFAM: Thioesterase superfamily; TIGRFAM: acyl-CoA thioester hydrolase, YbgC/YbaW family YP_004414052.1 COGs: COG0462 Phosphoribosylpyrophosphate synthetase; InterPro IPR000836:IPR005946; KEGG: vpr:Vpar_0608 ribose-phosphate pyrophosphokinase; PFAM: Phosphoribosyltransferase; PRIAM: Ribose-phosphate diphosphokinase; SPTR: Ribose-phosphate pyrophosphokinase; TIGRFAM: Phosphoribosyl pyrophosphokinase; IMG reference gene:2504587125; PFAM: Phosphoribosyl transferase domain; TIGRFAM: ribose-phosphate pyrophosphokinase YP_004414053.1 COGs: COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains); HAMAP: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; InterPro IPR005835:IPR001451:IPR005882; KEGG: afn:Acfer_1446 UDP-N-acetylglucosamine pyrophosphorylase; PFAM: Nucleotidyl transferase; Bacterial transferase hexapeptide repeat; PRIAM: Glucosamine-1-phosphate N-acetyltransferase; SPTR: Bifunctional protein glmU; TIGRFAM: Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase; IMG reference gene:2504587126; PFAM: Nucleotidyl transferase; TIGRFAM: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase YP_004414054.1 IMG reference gene:2504587127 YP_004414055.1 COGs: COG1802 Transcriptional regulators; InterPro IPR011711:IPR000524; KEGG: vpr:Vpar_1548 transcriptional regulator, GntR family; PFAM: GntR, C-terminal; HTH transcriptional regulator, GntR; SMART: GntR, C-terminal; HTH transcriptional regulator, GntR; SPTR: Transcriptional regulator, GntR family; IMG reference gene:2504587128; PFAM: Bacterial regulatory proteins, gntR family; FCD domain YP_004414056.1 COGs: COG1947 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase; HAMAP: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; InterPro IPR006204:IPR013750:IPR004424; KEGG: bha:BH0061 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; PFAM: GHMP kinase; GHMP kinase, C-terminal; PRIAM: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; SPTR: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; IMG reference gene:2504587129; PFAM: GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase YP_004414057.1 COGs: COG2217 Cation transport ATPase; InterPro IPR008250:IPR005834; KEGG: cpf:CPF_0534 copper-translocating P-type ATPase; PFAM: Haloacid dehalogenase-like hydrolase; ATPase, P-type, ATPase-associated domain; PRIAM: Copper-exporting ATPase; SPTR: Copper-exporting ATPase; IMG reference gene:2504587130; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004414058.1 COGs: COG1271 Cytochrome bd-type quinol oxidase subunit 1; InterPro IPR002585; KEGG: drm:Dred_1639 cytochrome bd ubiquinol oxidase, subunit I; PFAM: Cytochrome d ubiquinol oxidase, subunit I; SPTR: Cytochrome D ubiquinol oxidase, subunit 1; IMG reference gene:2504587131; PFAM: Bacterial Cytochrome Ubiquinol Oxidase YP_004414059.1 COGs: COG1294 Cytochrome bd-type quinol oxidase subunit 2; InterPro IPR003317; KEGG: dhd:Dhaf_1311 cytochrome d ubiquinol oxidase, subunit II; PFAM: Cytochrome d ubiquinol oxidase, subunit II; SPTR: Cytochrome D ubiquinol oxidase, subunit II; TIGRFAM: Cytochrome d ubiquinol oxidase, subunit II; IMG reference gene:2504587132; PFAM: Cytochrome oxidase subunit II; TIGRFAM: cytochrome d oxidase, subunit II (cydB) YP_004414060.1 COGs: COG4988 ABC-type transport system involved in cytochrome bd biosynthesis ATPase and permease components; InterPro IPR014216:IPR003593:IPR001140:IPR003439; KEGG: sma:SAV_4258 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; ABC transporter, transmembrane domain; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, CydDC cysteine exporter family, permease/ATP-binding protein CydD; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD; IMG reference gene:2504587133; PFAM: ABC transporter; ABC transporter transmembrane region; TIGRFAM: thiol reductant ABC exporter, CydD subunit YP_004414061.1 COGs: COG4987 ABC-type transport system involved in cytochrome bd biosynthesis fused ATPase and permease components; InterPro IPR003593:IPR014223:IPR003439; KEGG: tcu:Tcur_0354 cysteine ABC transporterppermease/ATP-binding protein CydC; PFAM: ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, CydDC cysteine exporter family, permease/ATP-binding protein CydC; TIGRFAM: ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC; IMG reference gene:2504587134; PFAM: ABC transporter YP_004414062.1 COGs: COG3633 Na+/serine symporter; HAMAP: Serine/threonine transporter SstT; InterPro IPR001991:IPR023025; KEGG: afn:Acfer_1269 sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter; SPTR: Serine/threonine transporter sstT; IMG reference gene:2504587135; PFAM: Sodium:dicarboxylate symporter family YP_004414063.1 InterPro IPR001119; KEGG: afn:Acfer_1668 S-layer domain protein; PFAM: S-layer homology domain; SPTR: Putative S-layer domain protein; IMG reference gene:2504587136; PFAM: S-layer homology domain YP_004414064.1 KEGG: efa:EF2164 hypothetical protein; SPTR: Putative membrane protein; IMG reference gene:2504587137 YP_004414065.1 COGs: COG3394 conserved hypothetical protein; InterPro IPR006879:IPR017836; KEGG: afn:Acfer_1035 YdjC family protein; PFAM: Uncharacterised protein family UPF0249/HpnK; SPTR: Molybdopterin converting factor, subunit 2; TIGRFAM: Hopanoid biosynthesis associated protein HpnK; IMG reference gene:2504587138; PFAM: YdjC-like protein; TIGRFAM: hopanoid biosynthesis associated protein HpnK YP_004414066.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587139 YP_004414067.1 COGs: COG0590 Cytosine/adenosine deaminase; InterPro IPR002125; KEGG: vpr:Vpar_0417 CMP/dCMP deaminase zinc-binding protein; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: tRNA-specific adenosine deaminase; IMG reference gene:2504587140; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004414068.1 SPTR: Putative rubrerythrin; IMG reference gene:2504587141 YP_004414069.1 InterPro IPR011528; KEGG: ilo:IL2046 hypothetical protein; PFAM: NERD; SPTR: Nuclease-related domain protein; IMG reference gene:2504587142; PFAM: Nuclease-related domain YP_004414070.1 InterPro IPR021652; KEGG: kse:Ksed_06230 hypothetical protein; PFAM: Telomeric repeat-binding factor 2; SPTR: rRNA-processing protein cgr-1; IMG reference gene:2504587143; PFAM: Telomeric repeat-binding factor 2 YP_004414071.1 COGs: COG0039 Malate/lactate dehydrogenase; HAMAP: Malate dehydrogenase, NAD-dependent; InterPro IPR001236:IPR022383:IPR011275; KEGG: bfs:BF3753 malate dehydrogenase; PFAM: Lactate/malate dehydrogenase, N-terminal; Lactate/malate dehydrogenase, C-terminal; PRIAM: Malate dehydrogenase; SPTR: Lactate dehydrogenase; IMG reference gene:2504587144; PFAM: lactate/malate dehydrogenase, alpha/beta C-terminal domain; lactate/malate dehydrogenase, NAD binding domain; TIGRFAM: malate dehydrogenase, NAD-dependent YP_004414072.1 COGs: COG1773 Rubredoxin; InterPro IPR004039; KEGG: afn:Acfer_0518 rubredoxin-type Fe(Cys)4 protein; PFAM: Rubredoxin-type Fe(Cys)4 protein; SPTR: Rubredoxin; IMG reference gene:2504587145; PFAM: Rubredoxin YP_004414073.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR011644:IPR004089; KEGG: cno:NT01CX_1000 methyl-accepting chemotaxis protein; PFAM: Haem NO binding; Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein; IMG reference gene:2504587146; PFAM: Heme NO binding; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004414074.1 InterPro IPR007267; KEGG: cbe:Cbei_2531 GtrA family protein; PFAM: GtrA-like protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587147; PFAM: GtrA-like protein YP_004414075.1 COGs: COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenase; InterPro IPR006115; KEGG: gwc:GWCH70_0924 6-phosphogluconate dehydrogenase NAD-binding; PFAM: 6-phosphogluconate dehydrogenase, NAD-binding; PRIAM: 2-hydroxy-3-oxopropionate reductase; SPTR: 2-hydroxy-3-oxopropionate reductase; IMG reference gene:2504587148; PFAM: NAD binding domain of 6-phosphogluconate dehydrogenase YP_004414076.1 SPTR: Putative dihydropteroate synthase; IMG reference gene:2504587149 YP_004414077.1 COGs: COG4864 conserved hypothetical protein; KEGG: vpr:Vpar_0350 hypothetical protein; SPTR: UPF0365 protein SELSPUOL_00504; IMG reference gene:2504587150; PFAM: SigmaW regulon antibacterial YP_004414078.1 COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: bsu:BSU25390 putative membrane bound hydrolase; PFAM: Nodulation efficiency, NfeD; SPTR: Putative protease/transporter; IMG reference gene:2504587151; PFAM: NfeD-like YP_004414079.1 COGs: COG0591 Na+/proline symporter; InterPro IPR001734; KEGG: nth:Nther_2163 Na+/solute symporter; PFAM: Sodium/solute symporter; SPTR: Transporter, solute:sodium symporter family; IMG reference gene:2504587152; PFAM: Sodium:solute symporter family YP_004414080.1 COGs: COG1362 Aspartyl aminopeptidase; InterPro IPR001948; KEGG: afn:Acfer_1038 aspartyl aminopeptidase; PFAM: Peptidase M18; PRIAM: Aspartyl aminopeptidase; SPTR: M18 family aminopeptidase; IMG reference gene:2504587153; PFAM: Aminopeptidase I zinc metalloprotease (M18) YP_004414081.1 InterPro IPR009875; KEGG: tjr:TherJR_1519 type IV pilus assembly PilZ; PFAM: Type IV pilus assembly PilZ; SPTR: Type IV pilus assembly protein PilZ; IMG reference gene:2504587154; PFAM: PilZ domain YP_004414082.1 InterPro IPR004843; KEGG: vpr:Vpar_1310 metallophosphoesterase; PFAM: Metallo-dependent phosphatase; SPTR: Putative metallophosphoesterase; IMG reference gene:2504587155; PFAM: Calcineurin-like phosphoesterase YP_004414083.1 COGs: COG4822 Cobalamin biosynthesis protein CbiK Co2+ chelatase; InterPro IPR010388; KEGG: vpr:Vpar_1135 anaerobic cobalt chelatase; PFAM: Anaerobic cobalt chelatase; PRIAM: Sirohydrochlorin cobaltochelatase; SPTR: Cobalt chelatase; IMG reference gene:2504587156; PFAM: Cobalt chelatase (CbiK) YP_004414084.1 KEGG: hoh:Hoch_3149 ATP-dependent DNA helicase, RecQ family; SPTR: Putative uncharacterized protein; IMG reference gene:2504587159 YP_004414085.1 KEGG: hmo:HM1_2253 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587160 YP_004414086.1 COGs: COG1315 polymerase most protein contain PALM domain HD hydrolase domain and Zn-ribbon domain; InterPro IPR005646; KEGG: toc:Toce_1126 protein of unknown function DUF342; PFAM: Protein of unknown function DUF342; SPTR: Putative uncharacterized protein; IMG reference gene:2504587161; PFAM: Protein of unknown function (DUF342) YP_004414087.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterProIPR007624:IPR014284:IPR007627:IPR007630:IPR 012845; KEGG: hmo:HM1_2251 RNA polymerase sigma factor, FliA/whig family; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 3; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG; RNA polymerase sigma-70; IMG reference gene:2504587162; PFAM: Sigma-70, region 4; Sigma-70 region 3; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, FliA/WhiG family; RNA polymerase sigma factor, sigma-70 family YP_004414088.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587163 YP_004414089.1 COGs: COG1871 Chemotaxis protein; stimulates methylation of MCP protein; InterPro IPR005659; KEGG: hmo:HM1_2249 chemotaxis protein CheD; PFAM: Chemoreceptor glutamine deamidase CheD; PRIAM: Protein-glutamine glutaminase; SPTR: Probable chemoreceptor glutamine deamidase CheD; IMG reference gene:2504587164; PFAM: CheD YP_004414090.1 COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597; KEGG: slp:Slip_0980 CheC, inhibitor of MCP methylation; PFAM: CheC-like protein; SPTR: Chemotaxis protein CheC; IMG reference gene:2504587165; PFAM: CheC-like family YP_004414091.1 COGs: COG0835 Chemotaxis signal transduction protein; InterPro IPR002545; KEGG: hmo:HM1_2248 purine-binding chemotaxis protein CheW; PFAM: CheW-like protein; SMART: CheW-like protein; SPTR: Chemotaxis protein CheW; IMG reference gene:2504587166; PFAM: CheW-like domain YP_004414092.1 COGs: COG0643 Chemotaxis protein histidine kinase and related kinase; InterProIPR008207:IPR010808:IPR004105:IPR003594:IPR 002545; KEGG: hmo:HM1_2247 CheA signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, P2 response regulator-binding; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; Signal transduction histidine kinase, subgroup, homodimeric; ATPase-like, ATP-binding domain; CheW-like protein; SMART: CheW-like protein; Signal transduction histidine kinase, phosphotransfer (Hpt) domain; ATPase-like, ATP-binding domain; SPTR: Histidine kinase; IMG reference gene:2504587167; PFAM: CheW-like domain; P2 response regulator binding domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; Signal transducing histidine kinase, homodimeric domain; Hpt domain YP_004414093.1 COGs: COG5581 glycosyltransferase; InterPro IPR009875; KEGG: nth:Nther_1416 type IV pilus assembly PilZ; PFAM: Type IV pilus assembly PilZ; SPTR: Type IV pilus assembly protein PilZ; IMG reference gene:2504587168; PFAM: PilZ domain YP_004414094.1 COGs: COG0455 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: amt:Amet_2701 cobyrinic acid a,c-diamide synthase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Flagellar synthesis regulator FleN; IMG reference gene:2504587169; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004414095.1 COGs: COG1419 Flagellar GTP-binding protein; InterPro IPR000897:IPR003593; KEGG: gym:GYMC10_4170 flagellar biosynthetic protein FlhF; PFAM: Signal recognition particle, SRP54 subunit, GTPase; SMART: Signal recognition particle, SRP54 subunit, GTPase; ATPase, AAA+ type, core; SPTR: Flagellar biosynthesis protein FlhF; IMG reference gene:2504587170; PFAM: SRP54-type protein, GTPase domain; TIGRFAM: flagellar biosynthetic protein FlhF YP_004414096.1 COGs: COG1298 Flagellar biosynthesis pathway component FlhA; InterPro IPR001712:IPR006301; KEGG: tjr:TherJR_1522 flagellar biosynthesis protein FlhA; PFAM: Type III secretion system FHIPEP; SPTR: Flagellar biosynthesis protein FlhA; TIGRFAM: Flagellar biosynthesis protein FlhA; IMG reference gene:2504587171; PFAM: FHIPEP family; TIGRFAM: flagellar biosynthesis protein FlhA YP_004414097.1 COGs: COG1377 Flagellar biosynthesis pathway component FlhB; InterPro IPR006135:IPR006136; KEGG: hmo:HM1_2242 flagellar biosynthetic protein FlhB, putative; PFAM: Type III secretion exporter; SPTR: Flagellar biosynthetic protein FlhB; TIGRFAM: Flagellar biosynthetic protein FlhB; IMG reference gene:2504587172; PFAM: FlhB HrpN YscU SpaS Family; TIGRFAM: type III secretion protein, YscU/HrpY family; flagellar biosynthetic protein FlhB YP_004414098.1 COGs: COG1684 Flagellar biosynthesis pathway component FliR; InterPro IPR002010:IPR006303; KEGG: tjr:TherJR_1524 flagellar biosynthetic protein FliR; PFAM: Type III secretion system inner membrane R protein; SPTR: Flagellar biosynthetic protein fliR; TIGRFAM: Flagellar biosynthesis protein FliR; IMG reference gene:2504587173; PFAM: Bacterial export proteins, family 1; TIGRFAM: flagellar biosynthetic protein FliR YP_004414099.1 COGs: COG1987 Flagellar biosynthesis pathway component FliQ; InterPro IPR006305:IPR002191; KEGG: aar:Acear_1627 flagellar biosynthetic protein FliQ; PFAM: Bacterial export protein FliQ, family 3; SPTR: Flagellar biosynthetic protein FliQ; TIGRFAM: Flagellar biosynthesis protein FliQ; IMG reference gene:2504587174; PFAM: Bacterial export proteins, family 3; TIGRFAM: flagellar biosynthetic protein FliQ YP_004414100.1 COGs: COG1338 Flagellar biosynthesis pathway component FliP; InterPro IPR005838:IPR005837; KEGG: tjr:TherJR_1526 flagellar biosynthetic protein FliP; PFAM: Type III secretion system inner membrane P protein; SPTR: Flagellar biosynthetic protein FliP; TIGRFAM: Flagellar transport protein FliP; IMG reference gene:2504587175; PFAM: FliP family; TIGRFAM: flagellar biosynthetic protein FliP YP_004414101.1 InterPro IPR022781; KEGG: dma:DMR_46190 putative flagellar protein FliO; PFAM: Flagellar biosynthesis protein, FliO; SPTR: Putative flagellar biosynthesis protein, FliO; TIGRFAM: Flagellar biosynthesis protein, FliO; IMG reference gene:2504587176; PFAM: Flagellar biosynthesis protein, FliO; TIGRFAM: flagellar biosynthetic protein FliO YP_004414102.1 COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: tjr:TherJR_1528 response regulator receiver protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Sporulation initiation phosphotransferase F; IMG reference gene:2504587177; PFAM: Response regulator receiver domain YP_004414103.1 COGs: COG1776 Chemotaxis protein CheC inhibitor of MCP methylation; InterPro IPR007597:IPR001543:IPR012826; KEGG: tjr:TherJR_1529 CheC, inhibitor of MCP methylation / FliN fusion protein; PFAM: Surface presentation of antigen (SpoA); CheC-like protein; SPTR: Flagellar motor switch phosphatase FliY; TIGRFAM: Flagellar motor switch FliN; IMG reference gene:2504587178; PFAM: Surface presentation of antigens (SPOA); CheC-like family; TIGRFAM: flagellar motor switch protein FliN YP_004414104.1 COGs: COG1868 Flagellar motor switch protein; InterPro IPR001689:IPR001543; KEGG: tjr:TherJR_1530 flagellar motor switch protein FliM; PFAM: Flagellar motor switch protein FliM; Surface presentation of antigen (SpoA); SPTR: Flagellar motor switch protein FliM; TIGRFAM: Flagellar motor switch protein FliM; IMG reference gene:2504587179; PFAM: Surface presentation of antigens (SPOA); Flagellar motor switch protein FliM; TIGRFAM: flagellar motor switch protein FliM YP_004414105.1 InterPro IPR005503; KEGG: cff:CFF8240_0923 flagellar basal body-associated protein FliL; PFAM: Flagellar basal body-associated protein FliL; SPTR: Flagellar basal body-associated protein FliL; IMG reference gene:2504587180; PFAM: Flagellar basal body-associated protein FliL YP_004414106.1 COGs: COG1582 Uncharacterized protein possibly involved in motility; InterPro IPR009384; KEGG: sth:STH1485 putative flagellar protein; PFAM: Flagellar; SPTR: Putative flagellar protein FlbD; IMG reference gene:2504587181; PFAM: Flagellar protein (FlbD) YP_004414107.1 COGs: COG1749 Flagellar hook protein FlgE; InterPro IPR010930:IPR020013:IPR011491:IPR001444; KEGG: hmo:HM1_2230 flagellar hook protein; PFAM: Domain of unknown function DUF1078, C-terminal; Flagellar basal body FlaE; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar hook protein FlgE; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504587182; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); Flagellar basal body protein FlaE; TIGRFAM: fagellar hook-basal body proteins YP_004414108.1 InterPro IPR013367; KEGG: hmo:HM1_2229 flagellar operon protein, putative; PFAM: Flagellar, putative; SPTR: Flagellar operon protein; TIGRFAM: Flagellar, putative; IMG reference gene:2504587183; PFAM: Protein of unknown function (DUF3766); TIGRFAM: flagellar operon protein YP_004414109.1 COGs: COG1843 Flagellar hook capping protein; InterPro IPR005648; KEGG: bse:Bsel_1748 flagellar hook capping protein; PFAM: Flagellar hook capping protein; SPTR: Flagellar hook capping protein; IMG reference gene:2504587184; PFAM: Flagellar hook capping protein YP_004414110.1 InterPro IPR021136; KEGG: ppm:PPSC2_c2094 flagellar hook-length control protein; PFAM: Flagellar hook-length control protein-like, C-terminal domain; SPTR: Putative flagellar hook-length control protein; IMG reference gene:2504587185; PFAM: Flagellar hook-length control protein FliK YP_004414111.1 InterPro IPR006668; KEGG: nth:Nther_1396 hypothetical protein; PFAM: Magnesium transporter, MgtE intracellular domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504587186; PFAM: MgtE intracellular N domain YP_004414112.1 COGs: COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM/invasin domains); InterPro IPR008258; KEGG: tte:TTE0883 lytic murein transglycosylase; PFAM: Lytic transglycosylase-like, catalytic; SPTR: Transglycosylase, SLT family; IMG reference gene:2504587187; PFAM: Transglycosylase SLT domain YP_004414113.1 InterPro IPR012823; KEGG: slp:Slip_0957 flagellar export protein FliJ; PFAM: Flagellar export FliJ; SPTR: Flagellar export protein FliJ; TIGRFAM: Flagellar export FliJ; IMG reference gene:2504587188; PFAM: Flagellar FliJ protein; TIGRFAM: flagellar export protein FliJ YP_004414114.1 COGs: COG1157 Flagellar biosynthesis/type III secretory pathway ATPase; InterProIPR003593:IPR004100:IPR000194:IPR005714:IPR 022425; KEGG: tjr:TherJR_1539 flagellar protein export ATPase FliI; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; PRIAM: H(+)-transporting two-sector ATPase; SMART: ATPase, AAA+ type, core; SPTR: Flagellar protein export ATPase FliI; TIGRFAM: ATPase, type III secretion system, FliI/YscN; Flagellar export ATPase, FliI, clade 2; IMG reference gene:2504587189; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATPase FliI/YscN family; type III secretion apparatus H+-transporting two-sector ATPase; flagellar protein export ATPase FliI YP_004414115.1 COGs: COG1317 Flagellar biosynthesis/type III secretory pathway protein; InterPro IPR018035; KEGG: hmo:HM1_2223 flagellar assembly protein FliH, putative; PFAM: Flagellar assembly protein FliH/Type III secretion system HrpE; SPTR: Putative flagellar assembly protein FliH; IMG reference gene:2504587190; PFAM: Flagellar assembly protein FliH YP_004414116.1 COGs: COG1536 Flagellar motor switch protein; InterPro IPR006668:IPR023087:IPR000090; KEGG: tjr:TherJR_1541 flagellar motor switch protein FliG; PFAM: Flagellar motor switch protein FliG, C-terminal; Magnesium transporter, MgtE intracellular domain; SPTR: Flagellar motor switch protein FliG; TIGRFAM: Flagellar motor switch protein FliG; IMG reference gene:2504587191; PFAM: FliG C-terminal domain; TIGRFAM: flagellar motor switch protein FliG YP_004414117.1 COGs: COG1766 Flagellar biosynthesis/type III secretory pathway lipoprotein; InterPro IPR000067:IPR006182:IPR013556; KEGG: tjr:TherJR_1542 flagellar M-ring protein FliF; PFAM: Secretory protein YscJ/FliF; Flagellar M-ring C-terminal; SPTR: Flagellar M-ring protein FliF; TIGRFAM: Flagellar FliF M-ring protein; IMG reference gene:2504587192; PFAM: Flagellar M-ring protein C-terminal; Secretory protein of YscJ/FliF family; TIGRFAM: flagellar basal-body M-ring protein/flagellar hook-basal body protein (fliF) YP_004414118.1 COGs: COG1677 Flagellar hook-basal body protein; InterPro IPR001624; KEGG: hmo:HM1_2220 flagellar hook-basal body complex protein FliE, putative; PFAM: Flagellar hook-basal body complex protein FliE; SPTR: Flagellar hook-basal body complex protein fliE; TIGRFAM: Flagellar hook-basal body complex protein FliE; IMG reference gene:2504587193; PFAM: Flagellar hook-basal body complex protein FliE; TIGRFAM: flagellar hook-basal body complex protein FliE YP_004414119.1 COGs: COG1558 Flagellar basal body rod protein; InterPro IPR010930:IPR006299:IPR001444; KEGG: toc:Toce_1093 flagellar basal-body rod protein FlgC; PFAM: Domain of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgC; TIGRFAM: Flagellar basal-body rod protein FlgC; IMG reference gene:2504587194; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: flagellar basal-body rod protein FlgC YP_004414120.1 COGs: COG1815 Flagellar basal body protein; InterPro IPR001444:IPR006300; KEGG: mta:Moth_0768 flagellar basal-body rod protein FlgB; PFAM: Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgB; TIGRFAM: Flagellar basal-body rod protein FlgB; IMG reference gene:2504587195; PFAM: Flagella basal body rod protein; TIGRFAM: flagellar basal-body rod protein FlgB YP_004414121.1 COGs: COG4465 Pleiotropic transcriptional repressor; InterPro IPR014154:IPR013198:IPR010312; KEGG: hor:Hore_07580 transcriptional repressor CodY; PFAM: GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal; GTP-sensing helix-turn-helix, CodY, C-terminal; SPTR: GTP-sensing transcriptional pleiotropic repressor CodY; TIGRFAM: GTP-sensing transcriptional pleiotropic repressor CodY; IMG reference gene:2504587196; PFAM: CodY helix-turn-helix domain; CodY GAF-like domain; TIGRFAM: GTP-sensing transcriptional pleiotropic repressor CodY YP_004414122.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; HAMAP: NAD-dependent histone deacetylase, silent information regulator Sir2; InterPro IPR003000; KEGG: cpf:CPF_0249 NAD-dependent deacetylase; PFAM: NAD-dependent histone deacetylase, silent information regulator Sir2; SPTR: NAD-dependent deacetylase; IMG reference gene:2504587197; PFAM: Sir2 family YP_004414123.1 COGs: COG3914 O-linked N-acetylglucosamine transferase SPINDLY family; KEGG: azl:AZL_f01630 TPR repeat-containing protein; SPTR: Putative tetratricopeptide repeat-containing domain protein; IMG reference gene:2504587198 YP_004414124.1 KEGG: chy:CHY_0980 glycosyl transferase family protein; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504587199 YP_004414125.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587200 YP_004414126.1 KEGG: bpf:BpOF4_06165 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587201 YP_004414127.1 COGs: COG0860 N-acetylmuramoyl-L-alanine amidase; InterPro IPR002508:IPR021731; KEGG: vpr:Vpar_1044 cell wall hydrolase/autolysin; PFAM: Cell wall hydrolase/autolysin, catalytic; Localisation of periplasmic protein complexes; PRIAM: N-acetylmuramoyl-L-alanine amidase; SMART: Cell wall hydrolase/autolysin, catalytic; SPTR: N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504587202; PFAM: N-acetylmuramoyl-L-alanine amidase; Localisation of periplasmic protein complexes; TIGRFAM: N-acetylmuramoyl-L-alanine amidase CwlD YP_004414128.1 COGs: COG1126 ABC-type polar amino acid transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: tmz:Tmz1t_3930 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Glutamine ABC transporter, ATP-binding protein; IMG reference gene:2504587203; PFAM: ABC transporter YP_004414129.1 COGs: COG0765 ABC-type amino acid transport system permease component; InterPro IPR010065:IPR000515; KEGG: dia:Dtpsy_0712 polar amino acid ABC transporter, inner membrane subunit; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: L-cystine ABC transporter, permease protein; TIGRFAM: Amino acid ABC transporter, permease protein, 3-TM domain, His/Glu/Gln/Arg/opine family; IMG reference gene:2504587204; PFAM: Binding-protein-dependent transport system inner membrane component; TIGRFAM: amine acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family YP_004414130.1 COGs: COG0841 Cation/multidrug efflux pump; InterPro IPR001036:IPR004764; KEGG: vpr:Vpar_1002 transporter, hydrophobe/amphiphile efflux-1 (HAE1) family; PFAM: Acriflavin resistance protein; SPTR: Multidrug efflux RND transporter MexF; TIGRFAM: Hydrophobe/amphiphile efflux-1 HAE1; IMG reference gene:2504587205; PFAM: AcrB/AcrD/AcrF family; TIGRFAM: The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family YP_004414131.1 COGs: COG0845 Membrane-fusion protein; InterPro IPR006143; KEGG: afn:Acfer_0246 efflux transporter, RND family, MFP subunit; PFAM: Secretion protein HlyD; SPTR: Putative multidrug efflux periplasmic linker protein BpeA; TIGRFAM: Secretion protein HlyD; IMG reference gene:2504587206; PFAM: HlyD family secretion protein; TIGRFAM: RND family efflux transporter, MFP subunit YP_004414132.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: vpr:Vpar_1337 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: HutW protein; IMG reference gene:2504587207; PFAM: Radical SAM superfamily YP_004414133.1 InterPro IPR008254; KEGG: vpr:Vpar_1338 flavodoxin family protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin family protein; IMG reference gene:2504587208 YP_004414134.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: vpr:Vpar_1339 TonB family protein; PFAM: TonB, C-terminal; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; IMG reference gene:2504587209; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain YP_004414135.1 COGs: COG0848 Biopolymer transport protein; InterPro IPR003400; KEGG: vpr:Vpar_1340 biopolymer transport protein ExbD/TolR; PFAM: Biopolymer transport protein ExbD/TolR; SPTR: Proton transporter, ExbD/TolR family; IMG reference gene:2504587210; PFAM: Biopolymer transport protein ExbD/TolR YP_004414136.1 COGs: COG0811 Biopolymer transport protein; InterPro IPR002898; KEGG: vpr:Vpar_1341 MotA/TolQ/ExbB proton channel; PFAM: MotA/TolQ/ExbB proton channel; SPTR: MotA/TolQ/ExbB proton channel family protein; IMG reference gene:2504587211; PFAM: MotA/TolQ/ExbB proton channel family YP_004414137.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1696 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Outer membrane ferric enterobactin receptor; IMG reference gene:2504587212; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004414138.1 COGs: COG0571 dsRNA-specific ribonuclease; InterPro IPR001159:IPR000999:IPR011907; KEGG: aar:Acear_1020 RNAse III; PFAM: Ribonuclease III; Double-stranded RNA-binding; PRIAM: Ribonuclease III; SMART: Ribonuclease III; Double-stranded RNA-binding; SPTR: Ribonuclease 3; TIGRFAM: Ribonuclease III, bacterial; IMG reference gene:2504587213; PFAM: Double-stranded RNA binding motif; RNase3 domain; TIGRFAM: ribonuclease III, bacterial YP_004414139.1 COGs: COG0304 3-oxoacyl-(acyl-carrier-protein) synthase; InterPro IPR014030:IPR014031:IPR017568:IPR020841; KEGG: afn:Acfer_1389 3-oxoacyl-(acyl-carrier-protein) synthase 2; PFAM: Beta-ketoacyl synthase, N-terminal; Beta-ketoacyl synthase, C-terminal; PRIAM: Beta-ketoacyl-acyl-carrier-protein synthase II; SMART: Polyketide synthase, beta-ketoacyl synthase domain; SPTR: Beta-ketoacyl-acyl-carrier-protein synthase II; TIGRFAM: 3-oxoacyl-[acyl-carrier-protein] synthase 2; IMG reference gene:2504587214; PFAM: Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: beta-ketoacyl-acyl-carrier-protein synthase II YP_004414140.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136; KEGG: vpr:Vpar_0701 2-nitropropane dioxygenase NPD; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Enoyl-(Acyl-carrier-protein) reductase II; IMG reference gene:2504587215; PFAM: 2-nitropropane dioxygenase YP_004414141.1 COGs: COG0236 Acyl carrier protein; HAMAP: Acyl carrier protein (ACP); InterPro IPR006163:IPR003231:IPR020806; KEGG: vpr:Vpar_0700 acyl carrier protein; PFAM: Phosphopantetheine-binding; SMART: Polyketide synthase, phosphopantetheine-binding; SPTR: Acyl carrier protein; TIGRFAM: Acyl carrier protein (ACP); IMG reference gene:2504587216; PFAM: Phosphopantetheine attachment site; TIGRFAM: acyl carrier protein YP_004414142.1 COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR011284; KEGG: afn:Acfer_1392 3-oxoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: 3-oxoacyl-[acyl-carrier-protein] reductase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase; IMG reference gene:2504587217; PFAM: short chain dehydrogenase; TIGRFAM: 3-oxoacyl-(acyl-carrier-protein) reductase YP_004414143.1 COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR004410:IPR020801; KEGG: vpr:Vpar_0698 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: Malonyl CoA-acyl carrier protein transacylase; IMG reference gene:2504587218; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase YP_004414144.1 COGs: COG2070 Dioxygenase related to 2-nitropropane dioxygenase; InterPro IPR004136:IPR017569; KEGG: vpr:Vpar_0697 enoyl-(acyl-carrier-protein) reductase II; PFAM: 2-nitropropane dioxygenase, NPD; SPTR: Putative enoyl-(Acyl-carrier-protein) reductase II; TIGRFAM: Enoyl-(acyl-carrier-protein) reductase II, putative; IMG reference gene:2504587219; PFAM: 2-nitropropane dioxygenase; TIGRFAM: putative enoyl-(acyl-carrier-protein) reductase II YP_004414145.1 COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; HAMAP: Phospholipid biosynthesis protein, PlsX-like; InterPro IPR003664:IPR012281; KEGG: vpr:Vpar_0695 fatty acid/phospholipid synthesis protein PlsX; PFAM: Fatty acid synthesis PlsX protein; SPTR: Phosphate acyltransferase; TIGRFAM: Phospholipid biosynthesis protein, PlsX-like; IMG reference gene:2504587220; PFAM: Fatty acid synthesis protein; TIGRFAM: fatty acid/phospholipid synthesis protein PlsX YP_004414146.1 COGs: COG0333 Ribosomal protein L32; HAMAP: Ribosomal protein L32p; InterPro IPR002677; KEGG: afn:Acfer_1398 ribosomal protein L32; PFAM: Ribosomal protein L32p; SPTR: 50S ribosomal protein L32 1; TIGRFAM: Ribosomal protein L32p; IMG reference gene:2504587221; PFAM: Ribosomal L32p protein family; TIGRFAM: ribosomal protein L32 YP_004414147.1 COGs: COG1399 metal-binding possibly nucleic acid-binding protein; InterPro IPR003772; KEGG: ttm:Tthe_1500 protein of unknown function DUF177; PFAM: Protein of unknown function DUF177; SPTR: Putative zinc finger protein; IMG reference gene:2504587222; PFAM: Uncharacterized ACR, COG1399 YP_004414148.1 COGs: COG2206 HD-GYP domain; InterPro IPR003607:IPR006674; KEGG: hor:Hore_22020 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative HD-GYP hydrolase domain containing protein; IMG reference gene:2504587223; PFAM: HD domain YP_004414149.1 COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: afn:Acfer_0272 secretion protein HlyD family protein; PFAM: Secretion protein HlyD; SPTR: HtpX protein; IMG reference gene:2504587224; PFAM: HlyD family secretion protein YP_004414150.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: glo:Glov_3106 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Monosaccharide-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP binding/permease protein; IMG reference gene:2504587225; PFAM: ABC transporter YP_004414151.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: str:Sterm_1478 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: Biotin synthesis protein BioC; IMG reference gene:2504587226; PFAM: ABC-2 type transporter YP_004414152.1 COGs: COG0842 ABC-type multidrug transport system permease component; InterPro IPR013525; KEGG: str:Sterm_4064 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: BioH protein; IMG reference gene:2504587227; PFAM: ABC-2 type transporter YP_004414153.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587228 YP_004414154.1 COGs: COG1220 ATP-dependent protease HslVU (ClpYQ) ATPase subunit; HAMAP: Heat shock protein HslU; InterPro IPR013093:IPR019489:IPR004491:IPR003593; KEGG: adg:Adeg_0577 ATP-dependent protease ATP-binding subunit HslU; PFAM: ATPase, AAA-2; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease ATPase subunit HslU; TIGRFAM: Heat shock protein HslU; IMG reference gene:2504587229; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: ATP-dependent protease HslVU, ATPase subunit YP_004414155.1 COGs: COG5405 ATP-dependent protease HslVU (ClpYQ) peptidase subunit; InterPro IPR001353:IPR022281; KEGG: dae:Dtox_1226 ATP-dependent protease peptidase subunit; PFAM: Proteasome, subunit alpha/beta; SPTR: ATP-dependent protease subunit HslV; TIGRFAM: ATP-dependent protease, HslV subunit; IMG reference gene:2504587230; PFAM: Proteasome subunit; TIGRFAM: ATP-dependent protease HslVU, peptidase subunit YP_004414156.1 COGs: COG1206 NAD(FAD)-utilizing enzyme possibly involved in translation; HAMAP: Folate-dependent ribothymidyl synthase; InterPro IPR002218:IPR004417; KEGG: adg:Adeg_0573 tRNA (uracil-5-)-methyltransferase Gid; PFAM: Glucose-inhibited division protein A-related; PRIAM:Methylenetetrahydrofolate--tRNA-(uracil-5-)-m ethyltransferase(FADH(2)-oxidizing); SPTR:Methylenetetrahydrofolate--tRNA-(uracil-5-)-me thyltransferaseTrmFO; TIGRFAM: Folate-dependent ribothymidyl synthase; IMG reference gene:2504587231; PFAM: Glucose inhibited division protein A; TIGRFAM: tRNA:m(5)U-54 methyltransferase YP_004414157.1 COGs: COG0550 Topoisomerase IA; InterProIPR009970:IPR006171:IPR013497:IPR013498:IPR 005733:IPR003601:IPR003602; KEGG: drm:Dred_1984 DNA topoisomerase I; PFAM: DNA topoisomerase, type IA, central; Toprim domain; Histone H1-like nucleoprotein HC2; DNA topoisomerase, type IA, zn finger; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial-type; IMG reference gene:2504587232; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; Histone H1-like nucleoprotein HC2; DNA topoisomerase; TIGRFAM: DNA topoisomerase I, bacterial YP_004414158.1 COGs: COG0758 Rossmann fold nucleotide-binding protein involved in DNA uptake; InterPro IPR003488; KEGG: gme:Gmet_0890 smf protein; PFAM: DNA recombination-mediator protein A; SPTR: DNA processing protein DprA; TIGRFAM: DNA recombination-mediator protein A; IMG reference gene:2504587233; PFAM: DNA recombination-mediator protein A; TIGRFAM: DNA protecting protein DprA YP_004414159.1 COGs: COG1539 Dihydroneopterin aldolase; InterPro IPR006156:IPR006157; KEGG: vpr:Vpar_0495 dihydroneopterin aldolase; PFAM: Dihydroneopterin aldolase; SMART: Dihydroneopterin aldolase; SPTR: Dihydroneopterin aldolase; TIGRFAM: Dihydroneopterin aldolase subgroup; Dihydroneopterin aldolase; IMG reference gene:2504587234; PFAM: Dihydroneopterin aldolase; TIGRFAM: dihydroneopterin aldolase; FolB domain YP_004414160.1 KEGG: adg:Adeg_1883 dihydropteroate synthase; SPTR: Dihydropteroate synthase; IMG reference gene:2504587235 YP_004414161.1 InterPro IPR010106; KEGG: afn:Acfer_1259 tetracycline resistance leader peptide; SPTR: Putative uncharacterized protein; TIGRFAM: Conserved hypothetical protein CHP01784; IMG reference gene:2504587236; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004414162.1 COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991:IPR006221; KEGG: nla:NLA_12940 anthranilate synthase component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component II; TIGRFAM: Anthranilate synthase, glutamine amidotransferase domain; IMG reference gene:2504587237; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase YP_004414163.1 COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805:IPR015890:IPR005256; KEGG: rrs:RoseRS_1455 anthranilate synthase component I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase component I; TIGRFAM: Anthranilate synthase component I, PabB-like; IMG reference gene:2504587238; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: anthranilate synthase component I, non-proteobacterial lineages YP_004414164.1 COGs: COG0159 Tryptophan synthase alpha chain; InterPro IPR002028; KEGG: adg:Adeg_1156 tryptophan synthase, alpha subunit; PFAM: Tryptophan synthase, alpha chain; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase alpha chain; TIGRFAM: Tryptophan synthase, alpha chain; IMG reference gene:2504587239; PFAM: Tryptophan synthase alpha chain; TIGRFAM: tryptophan synthase, alpha subunit YP_004414165.1 COGs: COG0133 Tryptophan synthase beta chain; InterPro IPR001926:IPR006654; KEGG: ana:all3794 tryptophan synthase subunit beta; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Tryptophan synthase; SPTR: Tryptophan synthase beta chain 1; TIGRFAM: Tryptophan synthase, beta chain; IMG reference gene:2504587240; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: tryptophan synthase, beta subunit YP_004414166.1 COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: gme:Gmet_2494 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Indole-3-glycerol phosphate synthase; IMG reference gene:2504587241; PFAM: Indole-3-glycerol phosphate synthase YP_004414167.1 COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: gem:GM21_2257 N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; IMG reference gene:2504587242; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase YP_004414168.1 IMG reference gene:2504587243 YP_004414169.1 COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: ypb:YPTS_3036 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative membrane protein; IMG reference gene:2504587244; PFAM: EamA-like transporter family YP_004414170.1 COGs: COG0122 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase; InterPro IPR003265; KEGG: elm:ELI_2109 DNA-3-methyladenine glycosylase II; PFAM: HhH-GPD domain; SMART: HhH-GPD domain; SPTR: Putative DNA-3-methyladenine glycosidase II; IMG reference gene:2504587245; PFAM: HhH-GPD superfamily base excision DNA repair protein YP_004414171.1 COGs: COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain; InterPro IPR012724:IPR001623:IPR002939:IPR001305; KEGG: afn:Acfer_0705 chaperone protein DnaJ; PFAM: Chaperone DnaJ, C-terminal; Heat shock protein DnaJ, cysteine-rich domain; Heat shock protein DnaJ, N-terminal; SMART: Heat shock protein DnaJ, N-terminal; SPTR: Chaperone protein dnaJ; TIGRFAM: Chaperone DnaJ; IMG reference gene:2504587246; PFAM: DnaJ C terminal region; DnaJ central domain (4 repeats); DnaJ domain; TIGRFAM: chaperone protein DnaJ YP_004414172.1 COGs: COG0443 Molecular chaperone; InterPro IPR013126:IPR012725; KEGG: tjr:TherJR_2450 chaperone protein DnaK; PFAM: Heat shock protein 70; SPTR: Chaperone protein dnaK; TIGRFAM: Chaperone DnaK; IMG reference gene:2504587247; PFAM: Hsp70 protein; TIGRFAM: chaperone protein DnaK YP_004414173.1 COGs: COG0576 Molecular chaperone GrpE (heat shock protein); HAMAP: GrpE nucleotide exchange factor; InterPro IPR000740; KEGG: bca:BCE_4396 heat shock protein GrpE; PFAM: GrpE nucleotide exchange factor; SPTR: Protein grpE; IMG reference gene:2504587248; PFAM: GrpE YP_004414174.1 COGs: COG1420 Transcriptional regulator of heat shock gene; InterPro IPR021153:IPR002571; KEGG: afn:Acfer_0702 heat-inducible transcription repressor HrcA; PFAM: Winged helix-turn-helix transcription repressor, HrcA, C-terminal; SPTR: Heat-inducible transcription repressor hrcA; TIGRFAM: Winged helix-turn-helix transcription repressor, HrcA; IMG reference gene:2504587249; PFAM: HrcA protein C terminal domain; TIGRFAM: heat shock gene repressor HrcA YP_004414175.1 KEGG: gvg:HMPREF0421_20942 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587250 YP_004414176.1 KEGG: gvg:HMPREF0421_20941 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587251 YP_004414177.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587252 YP_004414178.1 COGs: COG0635 Coproporphyrinogen III oxidase and related Fe-S oxidoreductase; InterPro IPR007197:IPR010723:IPR004559:IPR006638; KEGG: tjr:TherJR_2454 oxygen-independent coproporphyrinogen III oxidase; PFAM: Radical SAM; HemN, C-terminal; SMART: Elongator protein 3/MiaB/NifB; SPTR: Putative oxygen-independent coproporphyrinogen III oxidase; TIGRFAM: Putative oxygen-independent coproporphyrinogen III oxidase; IMG reference gene:2504587253; PFAM: Radical SAM superfamily; HemN C-terminal region; TIGRFAM: putative oxygen-independent coproporphyrinogen III oxidase YP_004414179.1 COGs: COG0481 Membrane GTPase LepA; InterProIPR005225:IPR013842:IPR000795:IPR004161:IPR 006297:IPR000640; KEGG: dhd:Dhaf_4307 GTP-binding protein LepA; PFAM: Protein synthesis factor, GTP-binding; GTP-binding protein LepA, C-terminal; Translation elongation factor EFTu/EF1A, domain 2; Translation elongation factor EFG/EF2, C-terminal; SMART: Translation elongation factor EFG/EF2, C-terminal; SPTR: Elongation factor 4; TIGRFAM: GTP-binding protein LepA; Small GTP-binding protein; IMG reference gene:2504587254; PFAM: Elongation factor Tu domain 2; Elongation factor G C-terminus; Elongation factor Tu GTP binding domain; GTP-binding protein LepA C-terminus; TIGRFAM: GTP-binding protein LepA; small GTP-binding protein domain YP_004414180.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587255 YP_004414181.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR004013; KEGG: str:Sterm_1709 histidinol phosphate phosphatase HisJ family; PFAM: PHP, C-terminal; SPTR: Histidinol-phosphatase; IMG reference gene:2504587256; TIGRFAM: histidinol phosphate phosphatase HisJ family YP_004414182.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200:IPR000150; KEGG: sma:SAV_4444 hypothetical protein; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD hydrolase, IIB family; TIGRFAM: Cof protein; HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504587257; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004414183.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3350 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Radical SAM domain protein; IMG reference gene:2504587258; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ2; radical SAM additional 4Fe4S-binding domain YP_004414184.1 COGs: COG0535 Fe-S oxidoreductase; InterPro IPR007197:IPR006638; KEGG: dhd:Dhaf_3352 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Nitrite reductase heme biosynthesis J protein; IMG reference gene:2504587259; PFAM: Radical SAM superfamily; TIGRFAM: putative heme d1 biosynthesis radical SAM protein NirJ1; radical SAM additional 4Fe4S-binding domain YP_004414185.1 InterPro IPR001647; KEGG: tjr:TherJR_0157 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504587260; PFAM: Bacterial regulatory proteins, tetR family YP_004414186.1 COGs: COG1284 conserved hypothetical protein; InterPro IPR019264:IPR003740; KEGG: bbe:BBR47_26440 hypothetical protein; PFAM: Domain of unknown function DUF2179; Protein of unknown function DUF161; SPTR: Putative membrane protein; IMG reference gene:2504587262; PFAM: Uncharacterized BCR, YitT family COG1284; Uncharacterized protein conserved in bacteria (DUF2179) YP_004414187.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: vpr:Vpar_0198 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Phosphonate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ferrichrome transport ATP-binding protein FhuC; IMG reference gene:2504587263; PFAM: ABC transporter YP_004414188.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: vpr:Vpar_0197 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: Hemin ABC transporter, permease protein; IMG reference gene:2504587264; PFAM: FecCD transport family YP_004414189.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: vpr:Vpar_0196 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Periplasmic binding protein; IMG reference gene:2504587265; PFAM: Periplasmic binding protein YP_004414190.1 COGs: COG0194 Guanylate kinase; InterPro IPR008144:IPR008145; KEGG: saf:SULAZ_0277 guanylate kinase; PFAM: Guanylate kinase; SMART: Guanylate kinase/L-type calcium channel; SPTR: Putative guanylate kinase; IMG reference gene:2504587266; PFAM: Guanylate kinase YP_004414191.1 COGs: COG0498 Threonine synthase; InterPro IPR001926; KEGG: mpd:MCP_0979 putative threonine synthase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; PRIAM: Threonine synthase; SPTR: Threonine synthase; IMG reference gene:2504587267; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine synthase YP_004414192.1 COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005482:IPR005479:IPR005481; KEGG: tjr:TherJR_1719 acetyl-CoA carboxylase, biotin carboxylase; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Biotin carboxylase, C-terminal; Carbamoyl-phosphate synthase, large subunit, N-terminal; PRIAM: Biotin carboxylase; SMART: Biotin carboxylase, C-terminal; SPTR: Acetyl-CoA carboxylase, biotin carboxylase subunit; IMG reference gene:2504587268; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: acetyl-CoA carboxylase, biotin carboxylase subunit YP_004414193.1 COGs: COG3077 DNA-damage-inducible protein J; InterPro IPR007337; KEGG: clo:HMPREF0868_0245 putative toxin-antitoxin system antitoxin component ribbon-helix-helix domain-containing protein; PFAM: RelB antitoxin; SPTR: Toxin-antitoxin system protein; TIGRFAM: RelB antitoxin; IMG reference gene:2504587269; PFAM: RelB antitoxin; TIGRFAM: addiction module antitoxin, RelB/DinJ family YP_004414194.1 KEGG: plt:Plut_0838 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587270 YP_004414195.1 InterPro IPR006597; PFAM: Sel1-like; SPTR: Sel1 repeat family protein; IMG reference gene:2504587271; PFAM: Sel1 repeat YP_004414196.1 KEGG: cce:Ccel_0191 Appr-1-p processing domain protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504587272 YP_004414197.1 COGs: COG2510 membrane protein; InterPro IPR000620; KEGG: ypb:YPTS_3036 hypothetical protein; PFAM: Drug/metabolite transporter; SPTR: Putative membrane protein; IMG reference gene:2504587274; PFAM: EamA-like transporter family YP_004414198.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: dhd:Dhaf_4874 ATPase; SPTR: ATPase; IMG reference gene:2504587275 YP_004414199.1 COGs: COG1196 Chromosome segregation ATPase; KEGG: cpr:CPR_0357 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587276 YP_004414200.1 KEGG: cpr:CPR_0356 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587277 YP_004414201.1 KEGG: cpr:CPR_0355 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587278 YP_004414202.1 KEGG: cpr:CPR_0354 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587279; PFAM: Uncharacterized protein conserved in bacteria C-term(DUF2220) YP_004414203.1 InterPro IPR003615; KEGG: cli:Clim_1461 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587280; TIGRFAM: TIGR02646 family protein YP_004414204.1 COGs: COG3950 ATP-binding protein involved in virulence; InterPro IPR003395; KEGG: cyp:PCC8801_0626 SMC domain protein; PFAM: RecF/RecN/SMC; SPTR: Hypothetical ATP-binding protein; IMG reference gene:2504587281; PFAM: RecF/RecN/SMC N terminal domain YP_004414205.1 COGs: COG1114 Branched-chain amino acid permease; InterPro IPR004685; KEGG: bld:BLi03102 BraB; PFAM: Branched-chain amino acid transport system II carrier protein; SPTR: Branched-chain amino acid transport system II carrier protein; TIGRFAM: Branched-chain amino acid transport system II carrier protein; IMG reference gene:2504587282; PFAM: Branched-chain amino acid transport protein; TIGRFAM: branched-chain amino acid uptake carrier YP_004414206.1 COGs: COG0178 Excinuclease ATPase subunit; InterPro IPR003593:IPR004602:IPR003439; KEGG: vpr:Vpar_0709 excinuclease ABC, A subunit; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Excinuclease ABC subunit A; TIGRFAM: Excinuclease ABC, A subunit; IMG reference gene:2504587283; PFAM: ABC transporter; TIGRFAM: excinuclease ABC, A subunit YP_004414207.1 COGs: COG0313 methyltransferase; InterPro IPR008189:IPR000878; KEGG: pth:PTH_0066 methyltransferase; PFAM: Tetrapyrrole methylase; SPTR: Tetrapyrrole methylase family protein; TIGRFAM: Uncharacterised protein family UPF0011; IMG reference gene:2504587284; PFAM: Tetrapyrrole (Corrin/Porphyrin) Methylases; TIGRFAM: probable S-adenosylmethionine-dependent methyltransferase, YraL family YP_004414208.1 COGs: COG1774 Uncharacterized homolog of PSP1; InterPro IPR007557; KEGG: afn:Acfer_0638 PSP1 domain protein; PFAM: PSP1, C-terminal; SPTR: Stage 0 sporulation protein YaaT; IMG reference gene:2504587285; PFAM: PSP1 C-terminal conserved region YP_004414209.1 COGs: COG2812 DNA polymerase III gamma/tau subunits; InterPro IPR003593:IPR003959; KEGG: geo:Geob_2151 DNA polymerase III, delta prime subunit; PFAM: ATPase, AAA-type, core; SMART: ATPase, AAA+ type, core; SPTR: DNA polymerase III, delta prime subunit; IMG reference gene:2504587286; PFAM: ATPase family associated with various cellular activities (AAA); TIGRFAM: DNA polymerase III, delta' subunit YP_004414210.1 COGs: COG1728 conserved hypothetical protein; InterPro IPR005585; KEGG: tjr:TherJR_0086 protein of unknown function DUF327; PFAM: Protein of unknown function DUF327; SPTR: Putative uncharacterized protein; IMG reference gene:2504587287; PFAM: Protein of unknown function (DUF327) YP_004414211.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: vpr:Vpar_0532 lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Putative lipid A biosynthesis acyltransferase; IMG reference gene:2504587288; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004414212.1 COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); HAMAP: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; InterPro IPR020573:IPR001451:IPR007691; KEGG: afn:Acfer_1692 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region; Bacterial transferase hexapeptide repeat; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; IMG reference gene:2504587289; PFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase YP_004414213.1 KEGG: aar:Acear_2198 outer membrane chaperone Skp (OmpH); SPTR: DNA-binding protein; IMG reference gene:2504587290 YP_004414214.1 KEGG: gsu:GSU3278 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587291 YP_004414215.1 InterPro IPR005632; KEGG: vpr:Vpar_0528 outer membrane chaperone Skp (OmpH); PFAM: Outer membrane chaperone Skp (OmpH); SMART: Outer membrane chaperone Skp (OmpH); SPTR: Chaperone protein skp; IMG reference gene:2504587292; PFAM: Outer membrane protein (OmpH-like) YP_004414216.1 KEGG: aco:Amico_1506 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587293 YP_004414217.1 COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184; KEGG: afn:Acfer_1696 surface antigen (D15); PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Outer membrane protein, OMP85 family; IMG reference gene:2504587294; PFAM: Surface antigen variable number repeat; Surface antigen; POTRA domain, ShlB-type; TIGRFAM: outer membrane protein assembly complex, YaeT protein YP_004414218.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587295 YP_004414219.1 COGs: COG1191 DNA-directed RNA polymerase specialized sigma subunit; InterPro IPR014284:IPR007627:IPR007630; KEGG: hor:Hore_17700 RNA polymerase, sigma 28 subunit, FliA/WhiG family; PFAM: RNA polymerase sigma-70 region 2; RNA polymerase sigma-70 region 4; SPTR: RNA polymerase sigma factor; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504587296; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004414220.1 COGs: COG2911 conserved hypothetical protein; InterPro IPR007452; KEGG: vpr:Vpar_0526 protein of unknown function DUF490; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein; IMG reference gene:2504587297; PFAM: Family of unknown function (DUF490) YP_004414221.1 COGs: COG1538 Outer membrane protein; InterPro IPR003423; KEGG: afn:Acfer_1698 outer membrane efflux protein; PFAM: Outer membrane efflux protein; SPTR: Putative outer membrane efflux protein; IMG reference gene:2504587298; PFAM: Outer membrane efflux protein YP_004414222.1 COGs: COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component; InterPro IPR003399; KEGG: afn:Acfer_1699 mammalian cell entry related domain protein; PFAM: Mammalian cell entry-related; SPTR: Putative ABC transport system substrate-binding protein; IMG reference gene:2504587299; PFAM: mce related protein; TIGRFAM: virulence factor Mce family protein YP_004414223.1 COGs: COG1127 ABC-type transport system involved in resistance to organic solvents ATPase component; InterPro IPR003593:IPR003439; KEGG: vpr:Vpar_0523 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Toluene tolerance ABC efflux transporter, ATP-binding protein; IMG reference gene:2504587300; PFAM: ABC transporter YP_004414224.1 COGs: COG0767 ABC-type transport system involved in resistance to organic solvents permease component; InterPro IPR003453; KEGG: vpr:Vpar_0522 protein of unknown function DUF140; PFAM: Domain of unknown function DUF140; SPTR: Toluene tolerance ABC efflux transporter, permease; TIGRFAM: Domain of unknown function DUF140; IMG reference gene:2504587301; PFAM: Domain of unknown function DUF140; TIGRFAM: conserved hypothetical integral membrane protein YP_004414225.1 KEGG: vpr:Vpar_0521 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587302; PFAM: SpoIVB peptidase S55 YP_004414226.1 SPTR: Putative Acetyl-CoA carboxylase alpha chain; IMG reference gene:2504587303 YP_004414227.1 COGs: COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase; InterPro IPR018711:IPR021731; KEGG: afn:Acfer_1704 N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase-like exopolysaccharide biosynthesis protein; PFAM: Phosphodiester alpha-GlcNAcase; Localisation of periplasmic protein complexes; SPTR: Putative secreted protein; IMG reference gene:2504587304; PFAM: Predicted periplasmic protein (DUF2233); Localisation of periplasmic protein complexes YP_004414228.1 COGs: COG0206 Cell division GTPase; InterPro IPR003008:IPR018316:IPR000158; KEGG: tjr:TherJR_2152 cell division protein FtsZ; PFAM: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SMART: Tubulin/FtsZ, GTPase domain; Tubulin/FtsZ, 2-layer sandwich domain; SPTR: Cell division protein ftsZ; TIGRFAM: Cell division protein FtsZ, N-terminal; IMG reference gene:2504587305; PFAM: Tubulin/FtsZ family, GTPase domain; FtsZ family, C-terminal domain; TIGRFAM: cell division protein FtsZ YP_004414229.1 COGs: COG3856 conserved hypothetical protein (small basic protein); InterPro IPR009709; KEGG: mta:Moth_0848 hypothetical protein; PFAM: Protein of unknown function DUF1290; SPTR: Small basic protein; IMG reference gene:2504587306; PFAM: Protein of unknown function (DUF1290) YP_004414230.1 COGs: COG3879 conserved hypothetical protein; InterPro IPR010273; KEGG: afn:Acfer_1298 protein of unknown function DUF881; PFAM: Protein of unknown function DUF881; SPTR: Putative membrane protein; IMG reference gene:2504587307; PFAM: Bacterial protein of unknown function (DUF881) YP_004414231.1 COGs: COG1589 Cell division septal protein; InterPro IPR005548:IPR013685; KEGG: vpr:Vpar_1110 polypeptide-transport-associated domain protein FtsQ-type; PFAM: Polypeptide-transport-associated, FtsQ-type; Cell division protein FtsQ; SPTR: Putative cell division protein FtsQ; IMG reference gene:2504587308; PFAM: Cell division protein FtsQ; POTRA domain, FtsQ-type YP_004414232.1 COGs: COG1181 D-alanine-D-alanine ligase and related ATP-grasp protein; InterPro IPR005905:IPR011095:IPR011127; KEGG: vpr:Vpar_1111 D-alanine/D-alanine ligase; PFAM: D-alanine--D-alanine ligase, C-terminal; D-alanine--D-alanine ligase, N-terminal; PRIAM: D-alanine--D-alanine ligase; SPTR: D-alanine--D-alanine ligase; TIGRFAM: D-alanine--D-alanine ligase; IMG reference gene:2504587309; PFAM: D-ala D-ala ligase C-terminus; D-ala D-ala ligase N-terminus; TIGRFAM: D-alanine--D-alanine ligase YP_004414233.1 COGs: COG0773 UDP-N-acetylmuramate-alanine ligase; HAMAP: UDP-N-acetylmuramate-alanine ligase; InterPro IPR000713:IPR013221:IPR004101:IPR005758; KEGG: afn:Acfer_1301 UDP-N-acetylmuramate/alanine ligase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM: UDP-N-acetylmuramate--L-alanine ligase; SPTR: UDP-N-acetylmuramate--L-alanine ligase; TIGRFAM: UDP-N-acetylmuramate-alanine ligase; IMG reference gene:2504587310; PFAM: Mur ligase family, catalytic domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramate--alanine ligase YP_004414234.1 COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR007235:IPR006009:IPR004276; KEGG: vpr:Vpar_1113 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; PFAM: Glycosyl transferase, family 28, C-terminal; Glycosyl transferase, family 28; SPTR:UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; TIGRFAM: N-acetylglucosaminyltransferase, MurG; IMG reference gene:2504587311; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; TIGRFAM: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase YP_004414235.1 COGs: COG0771 UDP-N-acetylmuramoylalanine-D-glutamate ligase; HAMAP: UDP-N-acetylmuramoylalanine-D-glutamate ligase; InterPro IPR006076:IPR013221:IPR004101:IPR005762; KEGG: tpd:Teth39_0811 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; PFAM: Mur ligase, central; FAD dependent oxidoreductase; Mur ligase, C-terminal; SPTR: UDP-N-acetylmuramoylalanine--D-glutamate ligase; TIGRFAM: UDP-N-acetylmuramoylalanine-D-glutamate ligase; IMG reference gene:2504587312; PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Mur ligase family, glutamate ligase domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_004414236.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR003524:IPR018480:IPR000715; KEGG: afl:Aflv_1833 phospho-N-acetylmuramoyl-pentapeptide-transferase; PFAM: Glycosyl transferase, family 4; Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site; SPTR:Phospho-N-acetylmuramoyl-pentapeptide-transfer ase; TIGRFAM: Phospho-N-acetylmuramoyl-pentapeptide transferase; IMG reference gene:2504587313; PFAM: Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1; Glycosyl transferase family 4; TIGRFAM: phospho-N-acetylmuramoyl-pentapeptide-transferase YP_004414237.1 COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; HAMAP:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-di aminopimelateligase; InterProIPR000713:IPR013221:IPR004101:IPR005761:IPR 005863; KEGG: hoh:Hoch_1954 UDP-N-acetylmuramyl-tripeptide synthetase; PFAM: Mur ligase, central; Mur ligase, N-terminal; Mur ligase, C-terminal; PRIAM:UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelateligase.,UDP-N-acetylmuramoyl-tripeptide-- D-alanyl-D-alanineligase; SPTR:UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-al anineligase; TIGRFAM:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6- diaminopimelate ligase; UDP-MurNAc-pentapeptide synthetase; IMG reference gene:2504587314; PFAM: Mur ligase family, glutamate ligase domain; Mur ligase family, catalytic domain; Mur ligase middle domain; TIGRFAM: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; UDP-N-acetylmuramyl-tripeptide synthetase YP_004414238.1 InterPro IPR007082; KEGG: mta:Moth_0836 cell division protein FtsL; PFAM: Cell division protein FtsL; SPTR: Putative cell division protein FtsL; IMG reference gene:2504587315; PFAM: Cell division protein FtsL; TIGRFAM: cell division protein FtsL YP_004414239.1 COGs: COG0275 S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis; InterPro IPR002903; KEGG: afn:Acfer_1308 S-adenosyl-methyltransferase MraW; PFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; SPTR: Ribosomal RNA small subunit methyltransferase H; TIGRFAM: S-adenosyl-L-methionine-dependent methyltransferase, MraW; IMG reference gene:2504587316; PFAM: MraW methylase family; TIGRFAM: S-adenosyl-methyltransferase MraW YP_004414240.1 COGs: COG2001 conserved hypothetical protein; InterPro IPR020603:IPR003444; KEGG: tmt:Tmath_1482 MraZ protein; PFAM: MraZ domain; SPTR: Protein MraZ; TIGRFAM: MraZ; IMG reference gene:2504587317; PFAM: MraZ protein; TIGRFAM: mraZ protein YP_004414241.1 COGs: COG0726 xylanase/chitin deacetylase; InterPro IPR002509; KEGG: vpr:Vpar_0474 polysaccharide deacetylase; PFAM: Polysaccharide deacetylase; SPTR: Polysaccharide deacetylase family protein; IMG reference gene:2504587318; PFAM: Polysaccharide deacetylase YP_004414242.1 COGs: COG2268 conserved hypothetical protein; InterPro IPR001107; KEGG: bpb:bpr_III014 SPFH domain/band 7 family protein; PFAM: Band 7 protein; SMART: Band 7 protein; SPTR: Epidermal surface antigen; IMG reference gene:2504587319; PFAM: SPFH domain / Band 7 family YP_004414243.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: eel:EUBELI_20041 chromate transporter; PFAM: Chromate transporter; SPTR: Chromate transport protein; IMG reference gene:2504587320; PFAM: Chromate transporter YP_004414244.1 COGs: COG2059 Chromate transport protein ChrA; InterPro IPR003370; KEGG: csh:Closa_0917 chromate transporter; PFAM: Chromate transporter; SPTR: Putative chromate transport protein; IMG reference gene:2504587321; PFAM: Chromate transporter YP_004414245.1 KEGG: afn:Acfer_0202 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587322 YP_004414246.1 COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR005546:IPR006315; KEGG: vpr:Vpar_1322 outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta-domain; SMART: Autotransporter beta-domain; SPTR: Putative outer membrane autotransporter barrel domain protein; TIGRFAM: Outer membrane autotransporter barrel; IMG reference gene:2504587323; PFAM: Autotransporter beta-domain; TIGRFAM: outer membrane autotransporter barrel domain YP_004414247.1 COGs: COG4206 Outer membrane cobalamin receptor protein; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_0074 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative TonB-dependent receptor; IMG reference gene:2504587324; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004414248.1 InterPro IPR012307; KEGG: clj:CLJU_c22240 hypothetical protein; PFAM: Xylose isomerase, TIM barrel domain; SPTR: AP endonuclease, family 2; IMG reference gene:2504587325; PFAM: Xylose isomerase-like TIM barrel YP_004414249.1 COGs: COG2217 Cation transport ATPase; InterPro IPR001757:IPR008250:IPR006416:IPR005834; KEGG: vpr:Vpar_0252 heavy metal translocating P-type ATPase; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Copper-exporting ATPase; SPTR: Copper-exporting ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504587326; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: copper-(or silver)-translocating P-type ATPase; heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC YP_004414250.1 InterPro IPR001647; KEGG: vpr:Vpar_0251 transcriptional regulator, TetR family; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator, TetR family; IMG reference gene:2504587327; PFAM: Bacterial regulatory proteins, tetR family YP_004414251.1 KEGG: ere:EUBREC_2192 hypothetical protein; SPTR: Transposase; IMG reference gene:2504587328; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004414252.1 COGs: COG0355 F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); HAMAP: ATPase, F1 complex, delta/epsilon subunit; InterPro IPR001469:IPR020546:IPR020547; KEGG: bpf:BpOF4_06845 ATP synthase epsilon subunit; PFAM: ATPase, F1 complex, delta/epsilon subunit, N-terminal; ATPase, F1 complex, delta/epsilon subunit, C-terminal; SPTR: ATP synthase epsilon chain; TIGRFAM: ATPase, F1 complex, delta/epsilon subunit; IMG reference gene:2504587330; PFAM: ATP synthase, Delta/Epsilon chain, beta-sandwich domain; ATP synthase, Delta/Epsilon chain, long alpha-helix domain; TIGRFAM: ATP synthase, F1 epsilon subunit (delta in mitochondria) YP_004414253.1 COGs: COG0055 F0F1-type ATP synthase beta subunit; HAMAP: ATPase, F1 complex, beta subunit; InterProIPR003593:IPR005722:IPR004100:IPR000194:IPR 000793; KEGG: vpr:Vpar_1532 ATP synthase F1, beta subunit; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP synthase F1, beta subunit; TIGRFAM: ATPase, F1 complex, beta subunit; IMG reference gene:2504587331; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: ATP synthase, F1 beta subunit YP_004414254.1 COGs: COG0224 F0F1-type ATP synthase gamma subunit; HAMAP: ATPase, F1 complex, gamma subunit; InterPro IPR000131; KEGG: vpr:Vpar_1533 ATP synthase F1, gamma subunit; PFAM: ATPase, F1 complex, gamma subunit; SPTR: ATP synthase gamma chain; TIGRFAM: ATPase, F1 complex, gamma subunit; IMG reference gene:2504587332; PFAM: ATP synthase; TIGRFAM: ATP synthase, F1 gamma subunit YP_004414255.1 COGs: COG0056 F0F1-type ATP synthase alpha subunit; InterPro IPR004100:IPR000793:IPR000194:IPR005294; KEGG: vpr:Vpar_1534 ATP synthase F1, alpha subunit; PFAM: ATPase, alpha/beta subunit, nucleotide-binding domain; ATPase, F1/V1/A1 complex, alpha/beta subunit, C-terminal; ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal; SPTR: ATP synthase subunit alpha; TIGRFAM: ATPase, F1 complex, alpha subunit; IMG reference gene:2504587333; PFAM: ATP synthase alpha/beta family, beta-barrel domain; ATP synthase alpha/beta chain, C terminal domain; ATP synthase alpha/beta family, nucleotide-binding domain; TIGRFAM: proton translocating ATP synthase, F1 alpha subunit YP_004414256.1 COGs: COG0712 F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); InterPro IPR000711; KEGG: tjr:TherJR_2890 ATP synthase F1, delta subunit; PFAM: ATPase, F1 complex, OSCP/delta subunit; SPTR: ATP synthase F1, delta subunit; TIGRFAM: ATPase, F1 complex, OSCP/delta subunit; IMG reference gene:2504587334; PFAM: ATP synthase delta (OSCP) subunit; TIGRFAM: ATP synthase, F1 delta subunit YP_004414257.1 COGs: COG0711 F0F1-type ATP synthase subunit b; HAMAP: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; InterPro IPR005864:IPR002146; KEGG: dhd:Dhaf_4795 ATP synthase F0, B subunit; PFAM: ATPase, F0 complex, subunit B/B', bacterial/chloroplast; SPTR: ATP synthase subunit b; TIGRFAM: ATPase, F0 complex, subunit B, bacterial; IMG reference gene:2504587335; PFAM: ATP synthase B/B' CF(0); TIGRFAM: ATP synthase, F0 subunit b YP_004414258.1 InterPro IPR002379:IPR005953; KEGG: hmo:HM1_1099 ATP synthase f0, C subunit; PFAM: ATPase, F0/V0 complex, subunit C; SPTR: ATP synthase F0, C subunit; TIGRFAM: ATPase, F0 complex, subunit C, bacterial/chloroplast; IMG reference gene:2504587336; PFAM: ATP synthase subunit C; TIGRFAM: ATP synthase, F0 subunit c YP_004414259.1 COGs: COG0356 F0F1-type ATP synthase subunit a; InterPro IPR000568; KEGG: vpr:Vpar_1538 ATP synthase F0, A subunit; PFAM: ATPase, F0 complex, subunit A; SPTR: ATP synthase subunit a; TIGRFAM: ATPase, F0 complex, subunit A; IMG reference gene:2504587337; PFAM: ATP synthase A chain; TIGRFAM: ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes) YP_004414260.1 SPTR: Putative ATP synthase protein I; IMG reference gene:2504587338 YP_004414261.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587339 YP_004414262.1 COGs: COG0381 UDP-N-acetylglucosamine 2-epimerase; InterPro IPR003331; KEGG: pth:PTH_2821 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; PRIAM: UDP-N-acetylglucosamine 2-epimerase; SPTR: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; IMG reference gene:2504587340; PFAM: UDP-N-acetylglucosamine 2-epimerase; TIGRFAM: UDP-N-acetylglucosamine 2-epimerase YP_004414263.1 COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR000715; KEGG: afn:Acfer_1718 glycosyl transferase, family 4, conserved region; PFAM: Glycosyl transferase, family 4; SPTR: Undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase; IMG reference gene:2504587341; PFAM: Glycosyl transferase family 4 YP_004414264.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: cce:Ccel_3266 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504587342; PFAM: Transposase IS200 like YP_004414265.1 COGs: COG1544 Ribosome-associated protein Y (PSrp-1); InterPro IPR003489; KEGG: mta:Moth_0227 sigma 54 modulation protein / SSU ribosomal protein S30P; PFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; SPTR: Ribosomal subunit interface protein; TIGRFAM: Ribosomal protein S30Ae/sigma 54 modulation protein; IMG reference gene:2504587343; PFAM: Sigma 54 modulation protein / S30EA ribosomal protein; TIGRFAM: ribosomal subunit interface protein YP_004414266.1 KEGG: ere:EUBREC_2192 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587344; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004414267.1 COGs: COG1278 Cold shock protein; InterPro IPR011129:IPR002059; KEGG: cst:CLOST_2266 DNA-binding transcriptional repressor; PFAM: Cold-shock protein, DNA-binding; SMART: Cold shock protein; SPTR: Conserved domain protein; IMG reference gene:2504587345; PFAM: 'Cold-shock' DNA-binding domain YP_004414268.1 COGs: COG0337 3-dehydroquinate synthetase; HAMAP: 3-dehydroquinate synthase AroB, subgroup; InterPro IPR016037:IPR002658; KEGG: tjr:TherJR_1740 3-dehydroquinate synthase; PFAM: 3-dehydroquinate synthase AroB; PRIAM: 3-dehydroquinate synthase; SPTR: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase AroB, subgroup; IMG reference gene:2504587346; PFAM: 3-dehydroquinate synthase; TIGRFAM: 3-dehydroquinate synthase YP_004414269.1 COGs: COG0703 Shikimate kinase; InterPro IPR000623; KEGG: pth:PTH_1131 shikimate kinase; PFAM: Shikimate kinase; PRIAM: Shikimate kinase; SPTR: Shikimate kinase; IMG reference gene:2504587347; PFAM: Shikimate kinase YP_004414270.1 COGs: COG0082 Chorismate synthase; InterPro IPR000453; KEGG: gsu:GSU2027 chorismate synthase; PFAM: Chorismate synthase; PRIAM: Chorismate synthase; SPTR: Chorismate synthase; TIGRFAM: Chorismate synthase; IMG reference gene:2504587348; PFAM: Chorismate synthase; TIGRFAM: chorismate synthase YP_004414271.1 KEGG: tjr:TherJR_1743 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587349; PFAM: Pilus assembly protein, PilO YP_004414272.1 InterPro IPR007813; PFAM: Fimbrial assembly; SPTR: Putative general secretion pathway protein L; IMG reference gene:2504587350; PFAM: Fimbrial assembly protein (PilN) YP_004414273.1 SPTR: Transcriptional regulator protein, MarR family; IMG reference gene:2504587351 YP_004414274.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587352 YP_004414275.1 SPTR: TolQ protein; IMG reference gene:2504587353 YP_004414276.1 InterPro IPR012902; SPTR: Putative general secretion pathway protein H; IMG reference gene:2504587354; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004414277.1 InterPro IPR012902; KEGG: aar:Acear_1770 type II secretion system protein G; SPTR: General secretion pathway protein GspG; IMG reference gene:2504587356; PFAM: Prokaryotic N-terminal methylation motif; TIGRFAM: prepilin-type N-terminal cleavage/methylation domain YP_004414278.1 COGs: COG1459 Type II secretory pathway component PulF; InterPro IPR018076; KEGG: gka:GK2627 hypothetical protein; PFAM: Type II secretion system F domain; SPTR: General secretion pathway protein F; IMG reference gene:2504587357; PFAM: Bacterial type II secretion system protein F domain YP_004414279.1 COGs: COG2805 Tfp pilus assembly protein pilus retraction ATPase PilT; InterPro IPR001482:IPR006321; KEGG: pca:Pcar_0871 putative protein transport, PilT-like; PFAM: Type II secretion system protein E; SPTR: 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; TIGRFAM: Pilus retraction protein PilT; IMG reference gene:2504587358; PFAM: Type II/IV secretion system protein; TIGRFAM: pilus retraction protein PilT YP_004414280.1 COGs: COG2804 Type II secretory pathway ATPase PulE/Tfp pilus assembly pathway ATPase PilB; InterPro IPR001482:IPR003593; KEGG: adg:Adeg_1725 general secretory pathway protein E; PFAM: Type II secretion system protein E; SMART: ATPase, AAA+ type, core; SPTR: General secretory pathway protein E; IMG reference gene:2504587359; PFAM: Type II/IV secretion system protein YP_004414281.1 COGs: COG0169 Shikimate 5-dehydrogenase; HAMAP: Shikimate, quinate/shikimate dehydrogenase; InterPro IPR011342:IPR013708:IPR006151:IPR022893; KEGG: dly:Dehly_0222 shikimate 5-dehydrogenase; PFAM: Shikimate dehydrogenase substrate binding, N-terminal; Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase; SPTR: Shikimate dehydrogenase; TIGRFAM: Shikimate dehydrogenase; IMG reference gene:2504587360; PFAM: Shikimate dehydrogenase substrate binding domain; Shikimate / quinate 5-dehydrogenase; TIGRFAM: shikimate 5-dehydrogenase YP_004414282.1 COGs: COG0547 Anthranilate phosphoribosyltransferase; InterPro IPR005940:IPR000312:IPR017459; KEGG: bpb:bpr_I0012 anthranilate phosphoribosyltransferase TrpD; PFAM: Glycosyl transferase, family 3; Glycosyl transferase, family 3, N-terminal; PRIAM: Anthranilate phosphoribosyltransferase; SPTR: Anthranilate phosphoribosyltransferase; TIGRFAM: Anthranilate phosphoribosyl transferase; IMG reference gene:2504587361; PFAM: Glycosyl transferase family, a/b domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: anthranilate phosphoribosyltransferase YP_004414283.1 COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027; KEGG: phe:Phep_1419 NADH dehydrogenase (ubiquinone); PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: NADH dehydrogenase (ubiquinone); SPTR: NADH dehydrogenase; IMG reference gene:2504587362; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004414284.1 COGs: COG1512 Beta-propeller domains of methanol dehydrogenase type; InterPro IPR007621; KEGG: tpt:Tpet_1787 hypothetical protein; PFAM: Protein of unknown function DUF477; SPTR: Putative membrane protein; IMG reference gene:2504587363; PFAM: Domain of unknown function (DUF477) YP_004414285.1 COGs: COG1704 conserved hypothetical protein; InterPro IPR007156; KEGG: trq:TRQ2_1831 LemA family protein; PFAM: LemA; SPTR: LemA protein; IMG reference gene:2504587364; PFAM: LemA family YP_004414286.1 IMG reference gene:2504587367 YP_004414287.1 COGs: COG3345 Alpha-galactosidase; InterPro IPR000111; KEGG: ssa:SSA_0419 alpha-galactosidase, putative; PFAM: Glycoside hydrolase, clan GH-D; PRIAM: Alpha-galactosidase; SPTR: Alpha-galactosidase; IMG reference gene:2504587368; PFAM: Melibiase YP_004414288.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cbe:Cbei_4422 alanine racemase; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Ribose operon repressor; IMG reference gene:2504587369; PFAM: Bacterial regulatory proteins, lacI family; family YP_004414289.1 COGs: COG4468 Galactose-1-phosphate uridyltransferase; HAMAP: Galactose-1-phosphate uridylyltransferase; InterPro IPR000766:IPR005849:IPR005850; KEGG: cbe:Cbei_4421 galactose-1-phosphate uridylyltransferase; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal; Galactose-1-phosphate uridyl transferase, N-terminal; PRIAM: UDP-glucose--hexose-1-phosphate uridylyltransferase; SPTR: UTP--hexose-1-phosphate uridylyltransferase; TIGRFAM: Galactose-1-phosphate uridyl transferase, class II; IMG reference gene:2504587370; PFAM: Galactose-1-phosphate uridyl transferase, C-terminal domain; Galactose-1-phosphate uridyl transferase, N-terminal domain; TIGRFAM: galactose-1-phosphate uridylyltransferase, family 2 YP_004414290.1 COGs: COG1087 UDP-glucose 4-epimerase; InterPro IPR001509:IPR005886; KEGG: cbe:Cbei_4420 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; PRIAM: UDP-glucose 4-epimerase; SPTR: UDP-glucose 4-epimerase; TIGRFAM: UDP-glucose 4-epimerase; IMG reference gene:2504587371; PFAM: NAD dependent epimerase/dehydratase family; TIGRFAM: UDP-glucose-4-epimerase YP_004414291.1 COGs: COG0153 Galactokinase; HAMAP: Galactokinase, bacterial; InterProIPR000705:IPR019539:IPR006204:IPR013750:IPR 022963; KEGG: cac:CA_C2959 galactokinase; PFAM: Galactokinase galactose-binding domain; GHMP kinase; GHMP kinase, C-terminal; PRIAM: Galactokinase; SPTR: Galactokinase; TIGRFAM: Galactokinase; IMG reference gene:2504587372; PFAM: Galactokinase galactose-binding signature; GHMP kinases C terminal; GHMP kinases N terminal domain; TIGRFAM: galactokinase YP_004414292.1 COGs: COG3250 Beta-galactosidase/beta-glucuronidase; InterPro IPR006104:IPR006102:IPR006103:IPR004199; KEGG: bpb:bpr_I0279 beta-galactosidase Bga2A; PFAM: Glycoside hydrolase, family 2, TIM barrel; Glycoside hydrolase, family 2, carbohydrate-binding; Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich; Glycoside hydrolase, family 42, domain 5; SPTR: Beta-galactosidase; IMG reference gene:2504587373; PFAM: domain; Glycosyl hydrolases family 2, TIM barrel domain; Glycosyl hydrolases family 2, sugar binding domain; Beta galactosidase small chain YP_004414293.1 COGs: COG2211 Na+/melibiose symporter and related transporter; InterPro IPR001927:IPR011701; KEGG: lgs:LEGAS_0556 lactose permease; PFAM: Major facilitator superfamily MFS-1; SPTR: Lactose permease; TIGRFAM: Sodium:galactoside symporter; IMG reference gene:2504587374; PFAM: Major Facilitator Superfamily; TIGRFAM: sugar (Glycoside-Pentoside-Hexuronide) transporter YP_004414294.1 KEGG: cpy:Cphy_3531 hypothetical protein; SPTR: Putative cytidylate kinase; IMG reference gene:2504587375 YP_004414295.1 KEGG: dvm:DvMF_1880 outer membrane autotransporter barrel domain protein; SPTR: Putative outer membrane autotransporter barrel domain protein; IMG reference gene:2504587376 YP_004414296.1 COGs: COG1737 Transcriptional regulators; InterPro IPR001347:IPR000281; KEGG: cpe:CPE0197 hypothetical protein; PFAM: Helix-turn-helix protein RpiR; Sugar isomerase (SIS); SPTR: Putative transcriptional regulator GlvR; IMG reference gene:2504587377; PFAM: Helix-turn-helix domain, rpiR family; SIS domain YP_004414297.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterProIPR010975:IPR018113:IPR001127:IPR011535:IPR 003352; KEGG: cac:CA_C0532 PTS system, arbutin-like IIBC component; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: PTS system maltose-specific EIICB component; TIGRFAM: Phosphotransferase system, alpha-glucoside-specific IIBC component; Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system, glucose-like IIB component; IMG reference gene:2504587378; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component; PTS system, alpha-glucoside-specific IIBC component YP_004414298.1 COGs: COG0366 Glycosidase; InterPro IPR006589:IPR006047; KEGG: bmd:BMD_3759 oligo-1,6-glucosidase; PFAM: Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Oligo-1,6-glucosidase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: Alpha-glucosidase; IMG reference gene:2504587379; PFAM: Alpha amylase, catalytic domain YP_004414299.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR006379:IPR013200; KEGG: bhy:BHWA1_02099 putative hydrolase (HAD superfamily); PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD-superfamily hydrolase, subfamily IIB; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504587380; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: Cof subfamily of IIB subfamily of haloacid dehalogenase superfamily; HAD-superfamily hydrolase, subfamily IIB YP_004414300.1 COGs: COG5026 Hexokinase; InterPro IPR022673:IPR022672; KEGG: hmo:HM1_0763 hexokinase, putative; PFAM: Hexokinase, N-terminal; Hexokinase, C-terminal; PRIAM: Hexokinase; SPTR: Glucokinase; IMG reference gene:2504587381; PFAM: Hexokinase YP_004414301.1 InterPro IPR015077; KEGG: mta:Moth_2496 hypothetical protein; PFAM: Domain of unknown function DUF1858; SPTR: Putative uncharacterized protein; IMG reference gene:2504587382; PFAM: Domain of unknown function (DUF1858); TIGRFAM: hydrid cluster protein-associated redox disulfide domain YP_004414302.1 KEGG: afn:Acfer_0202 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587384 YP_004414303.1 InterPro IPR006641; KEGG: cyt:cce_0463 putative resolvase, RNase H-like fold; SMART: Resolvase, RNase H-like fold; SPTR: Putative uncharacterized protein; IMG reference gene:2504587385 YP_004414304.1 COGs: COG4372 Uncharacterized protein with the myosin-like domain; InterPro IPR021435; KEGG: afn:Acfer_1672 hypothetical protein; PFAM: Protein of unknown function DUF3084; SPTR: Putative uncharacterized protein; IMG reference gene:2504587386; PFAM: Protein of unknown function (DUF3084) YP_004414305.1 COGs: COG0795 permease; InterPro IPR005495; KEGG: vpr:Vpar_0550 permease YjgP/YjgQ family protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Membrane protein, YjgP/YjgQ family; IMG reference gene:2504587387; PFAM: Predicted permease YjgP/YjgQ family YP_004414306.1 COGs: COG1137 ABC-type (unclassified) transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: vpr:Vpar_0549 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Lipopolysaccharide ABC transporter, ATP-binding protein; IMG reference gene:2504587388; PFAM: ABC transporter YP_004414307.1 InterPro IPR005653; KEGG: vpr:Vpar_0548 OstA family protein; PFAM: Organic solvent tolerance-like, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504587389; PFAM: OstA-like protein YP_004414308.1 InterPro IPR010664; KEGG: afn:Acfer_1678 protein of unknown function DUF1239; PFAM: Lipopolysccharide assembly, LptC-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504587390; PFAM: Protein of unknown function (DUF1239) YP_004414309.1 COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: afn:Acfer_1679 lipid A biosynthesis acyltransferase; PFAM: Bacterial lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase; IMG reference gene:2504587391; PFAM: Bacterial lipid A biosynthesis acyltransferase YP_004414310.1 COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR010023:IPR013200:IPR006549; KEGG: alv:Alvin_2843 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PFAM: HAD superfamily hydrolase-like, type 3; PRIAM: 3-deoxy-manno-octulosonate-8-phosphatase; SPTR: 3-deoxy-manno-octulosonate-8-phosphatase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase; HAD-superfamily hydrolase, subfamily IIIA; IMG reference gene:2504587392; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family YP_004414311.1 COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; HAMAP: 3-deoxy-8-phosphooctulonate synthase; InterPro IPR006269:IPR006218; KEGG: vpr:Vpar_0543 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; IMG reference gene:2504587393; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase YP_004414312.1 COGs: COG1212 CMP-2-keto-3-deoxyoctulosonic acid synthetase; InterPro IPR004528:IPR003329; KEGG: vpr:Vpar_0542 3-deoxy-D-manno-octulosonatecytidylyltransferase; PFAM: Acylneuraminate cytidylyltransferase; PRIAM: 3-deoxy-manno-octulosonate cytidylyltransferase; SPTR: 3-deoxy-manno-octulosonate cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase; IMG reference gene:2504587394; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase YP_004414313.1 COGs: COG1519 3-deoxy-D-manno-octulosonic-acid transferase; InterPro IPR003758:IPR007507:IPR001296; KEGG: afn:Acfer_1684 tetraacyldisaccharide 4'-kinase; PFAM: Tetraacyldisaccharide 4'-kinase; Three-deoxy-D-manno-octulosonic-acid transferase, N-terminal; Glycosyl transferase, group 1; PRIAM: Tetraacyldisaccharide 4'-kinase; SPTR: 3-deoxy-D-manno-octulosonic-acid transferase; TIGRFAM: Tetraacyldisaccharide 4'-kinase; IMG reference gene:2504587395; PFAM: Glycosyl transferases group 1; 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Tetraacyldisaccharide-1-P 4'-kinase; TIGRFAM: tetraacyldisaccharide 4'-kinase YP_004414314.1 COGs: COG1132 ABC-type multidrug transport system ATPase and permease components; InterPro IPR003593:IPR001140:IPR011917:IPR003439; KEGG: afn:Acfer_1685 lipid A ABC exporter, fused ATPase and inner membrane subunits MsbA; PFAM: ABC transporter, transmembrane domain; ABC transporter-like; PRIAM: Xenobiotic-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Lipid A export permease/ATP-binding protein MsbA; TIGRFAM: ABC transporter, lipid A export, MsbA; IMG reference gene:2504587396; PFAM: ABC transporter transmembrane region; ABC transporter; TIGRFAM: lipid A export permease/ATP-binding protein MsbA YP_004414315.1 COGs: COG0763 Lipid A disaccharide synthetase; InterPro IPR003835; KEGG: afn:Acfer_1686 lipid-A-disaccharide synthase; PFAM: Glycosyl transferase, family 19; PRIAM: Lipid-A-disaccharide synthase; SPTR: Lipid-A-disaccharide synthase; TIGRFAM: Glycosyl transferase, family 19; IMG reference gene:2504587397; PFAM: Lipid-A-disaccharide synthetase; TIGRFAM: lipid-A-disaccharide synthase YP_004414316.1 COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: afn:Acfer_1687 protein of unknown function DUF1009; PFAM: Protein of unknown function DUF1009; SPTR: Putative uncharacterized protein; IMG reference gene:2504587398; PFAM: Protein of unknown function (DUF1009) YP_004414317.1 COGs: COG1043 Acyl-(acyl carrier protein); HAMAP:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; InterPro IPR010137:IPR001451; KEGG: vpr:Vpar_0535 acyl-(acyl-carrier-protein)--UDP-N-acetylglucosa mineO-acyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluc osamineO-acyltransferase; SPTR:Acyl-[acyl-carrier-protein]--UDP-N-acetylgluco samineO-acyltransferase; TIGRFAM:Acyl-[acyl-carrier-protein]--UDP-N-acetylgl ucosamineO-acyltransferase; IMG reference gene:2504587399; TIGRFAM: acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase YP_004414318.1 COGs: COG0764 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase; InterPro IPR010084:IPR013114; KEGG: afn:Acfer_1689 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase, FabA/FabZ; SPTR: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase; TIGRFAM: Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; IMG reference gene:2504587400; PFAM: FabA-like domain; TIGRFAM: beta-hydroxyacyl-[acyl carrier protein] dehydratase FabZ YP_004414319.1 COGs: COG0774 UDP-3-O-acyl-N-acetylglucosamine deacetylase; InterPro IPR004463; KEGG: afn:Acfer_1689 beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; PFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase; SPTR: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; TIGRFAM: UDP-3-O-acyl N-acetylglucosamine deacetylase; IMG reference gene:2504587401; PFAM: UDP-3-O-acyl N-acetylglycosamine deacetylase; TIGRFAM: UDP-3-0-acyl N-acetylglucosamine deacetylase YP_004414320.1 COGs: COG2131 Deoxycytidylate deaminase; InterPro IPR002125; KEGG: fnu:FN1902 deoxycytidylate deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; PRIAM: dCMP deaminase; SPTR: Putative deoxycytidylate deaminase; IMG reference gene:2504587402; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region YP_004414321.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR004089; KEGG: slp:Slip_1365 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; SMART: Chemotaxis methyl-accepting receptor, signalling; SPTR: Putative methyl-accepting chemotaxis protein signaling domain protein; IMG reference gene:2504587403; PFAM: Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004414322.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: vpr:Vpar_0306 UspA domain protein; PFAM: UspA; SPTR: Universal stress protein; IMG reference gene:2504587404; PFAM: Universal stress protein family YP_004414323.1 InterPro IPR014284:IPR007627:IPR007630; KEGG: ttm:Tthe_0707 putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: RNA polymerase sigma-70 region 4; RNA polymerase sigma-70 region 2; SPTR: DNA-directed RNA polymerase general stress sigma factor sigma-B; TIGRFAM: RNA polymerase sigma-70; IMG reference gene:2504587405; PFAM: Sigma-70, region 4; Sigma-70 region 2; TIGRFAM: RNA polymerase sigma factor, sigma-70 family YP_004414324.1 KEGG: toc:Toce_0474 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587406 YP_004414325.1 InterPro IPR006186:IPR004843; KEGG: sat:SYN_00526 calcineurin-like phosphoesterase; PFAM: Metallo-dependent phosphatase; SMART: Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase; SPTR: Ser/Thr protein phosphatase family protein; IMG reference gene:2504587407; PFAM: Calcineurin-like phosphoesterase YP_004414326.1 COGs: COG4624 Iron only hydrogenase large subunit C-terminal domain; InterPro IPR004108; KEGG: csh:Closa_3666 hydrogenase large subunit domain protein; PFAM: Iron hydrogenase, large subunit, C-terminal; SPTR: Hydrogenase subunit; IMG reference gene:2504587408; PFAM: Iron only hydrogenase large subunit, C-terminal domain YP_004414327.1 InterPro IPR001387; KEGG: amt:Amet_0838 helix-turn-helix domain-containing protein; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504587410; PFAM: Helix-turn-helix YP_004414328.1 KEGG: ere:EUBREC_1021 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587411 YP_004414329.1 COGs: COG0578 Glycerol-3-phosphate dehydrogenase; InterPro IPR007419:IPR017752:IPR006076; KEGG: drm:Dred_2844 FAD dependent oxidoreductase; PFAM: FAD dependent oxidoreductase; BFD-like [2Fe-2S]-binding domain; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, A subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic A subunit; IMG reference gene:2504587412; PFAM: BFD-like [2Fe-2S] binding domain; FAD dependent oxidoreductase; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit YP_004414330.1 COGs: COG3075 Anaerobic glycerol-3-phosphate dehydrogenase; InterPro IPR009158:IPR003953; KEGG: dds:Ddes_1520 anaerobic glycerol-3-phosphate dehydrogenase subunit B; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; PRIAM: Glycerol-3-phosphate dehydrogenase; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, B subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic B subunit; IMG reference gene:2504587413; PFAM: FAD binding domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, B subunit YP_004414331.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017:IPR017753; KEGG: dds:Ddes_1519 sn-glycerol-3-phosphate dehydrogenase subunit C; PFAM: Cysteine-rich domain; SPTR: Glycerol-3-phosphate dehydrogenase [NAD(P)+ ], anaerobic, C subunit; TIGRFAM: Glycerol-3-phosphate dehydrogenase, anaerobic C subunit; IMG reference gene:2504587414; PFAM: Cysteine-rich domain; TIGRFAM: glycerol-3-phosphate dehydrogenase, anaerobic, C subunit YP_004414332.1 COGs: COG0554 Glycerol kinase; InterPro IPR018485:IPR005999:IPR018484; KEGG: chy:CHY_1839 glycerol kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Glycerol kinase; SPTR: Glycerol kinase 2; TIGRFAM: Glycerol kinase; IMG reference gene:2504587415; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004414333.1 COGs: COG0580 Glycerol uptake facilitator and related permease (Major Intrinsic Protein Family); InterPro IPR000425; KEGG: tai:Taci_1557 major intrinsic protein; PFAM: Major intrinsic protein; SPTR: Glycerol uptake facilitator; IMG reference gene:2504587416; PFAM: Major intrinsic protein; TIGRFAM: MIP family channel proteins YP_004414334.1 COGs: COG0554 Glycerol kinase; InterPro IPR018485:IPR005999:IPR018484; KEGG: trq:TRQ2_1322 glycerol kinase; PFAM: Carbohydrate kinase, FGGY, N-terminal; Carbohydrate kinase, FGGY, C-terminal; PRIAM: Glycerol kinase; SPTR: Glycerol kinase; TIGRFAM: Glycerol kinase; IMG reference gene:2504587417; PFAM: FGGY family of carbohydrate kinases, N-terminal domain; FGGY family of carbohydrate kinases, C-terminal domain; TIGRFAM: glycerol kinase YP_004414335.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1343 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Putative TonB-dependent receptor plug domain protein; IMG reference gene:2504587418; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004414336.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR001898:IPR004680; KEGG: vpr:Vpar_1238 anion transporter; PFAM: Divalent ion symporter; SPTR: Cation transporter; TIGRFAM: Sodium/sulphate symporter; IMG reference gene:2504587419; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_004414337.1 COGs: COG0112 Glycine/serine hydroxymethyltransferase; InterPro IPR001085; KEGG: cni:Calni_0592 serine hydroxymethyltransferase; PFAM: Serine hydroxymethyltransferase; PRIAM: Glycine hydroxymethyltransferase; SPTR: Glycine hydroxymethyltransferase; IMG reference gene:2504587420; PFAM: Serine hydroxymethyltransferase YP_004414338.1 COGs: COG1620 L-lactate permease; InterPro IPR003804; KEGG: drm:Dred_2205 L-lactate transport; PFAM: L-lactate permease; SPTR: L-lactate permease; IMG reference gene:2504587421; PFAM: L-lactate permease; TIGRFAM: L-lactate transport YP_004414339.1 COGs: COG1139 conserved hypothetical protein containing a ferredoxin-like domain; InterPro IPR004017:IPR003741; KEGG: hmo:HM1_0363 4fe-4S ferredoxin, iron-sulfur binding protein, putative; PFAM: Domain of unknown function DUF162; Cysteine-rich domain; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504587422; PFAM: Cysteine-rich domain; Uncharacterised ACR, YkgG family COG1556; TIGRFAM: iron-sulfur cluster-binding protein YP_004414340.1 COGs: COG1556 conserved hypothetical protein; InterPro IPR003741; KEGG: dhd:Dhaf_3084 protein of unknown function DUF162; PFAM: Domain of unknown function DUF162; SPTR: Putative iron-sulfur cluster-binding protein; IMG reference gene:2504587423; PFAM: Uncharacterised ACR, YkgG family COG1556 YP_004414341.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: cpy:Cphy_1317 FAD linked oxidase domain-containing protein; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; IMG reference gene:2504587424; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_004414342.1 COGs: COG2025 Electron transfer flavoprotein alpha subunit; InterPro IPR014730:IPR014731; KEGG: clj:CLJU_c21580 putative electron transfer flavoprotein subunit alpha; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; Electron transfer flavoprotein, alpha subunit, C-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein, alpha subunit; IMG reference gene:2504587425; PFAM: Electron transfer flavoprotein domain; Electron transfer flavoprotein FAD-binding domain YP_004414343.1 COGs: COG2086 Electron transfer flavoprotein beta subunit; InterPro IPR014730; KEGG: cbl:CLK_0447 electron transfer flavoprotein, beta subunit/FixA family protein; PFAM: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SMART: Electron transfer flavoprotein, alpha/beta-subunit, N-terminal; SPTR: Electron transfer flavoprotein, beta subunit; IMG reference gene:2504587426; PFAM: Electron transfer flavoprotein domain YP_004414344.1 KEGG: vpr:Vpar_0135 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587427 YP_004414345.1 COGs: COG1080 Phosphoenolpyruvate-protein kinase (PTS system EI component); InterPro IPR006318:IPR008731:IPR008279:IPR000121; KEGG: hmo:HM1_0836 phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilising enzyme; Phosphotransferase system, PEP-utilising enzyme, N-terminal; PEP-utilising enzyme, mobile domain; PRIAM: Phosphoenolpyruvate--protein phosphotransferase; SPTR: Phosphoenolpyruvate-protein phosphotransferase; TIGRFAM: Phosphoenolpyruvate-protein phosphotransferase; IMG reference gene:2504587428; PFAM: PEP-utilising enzyme, mobile domain; PEP-utilising enzyme, TIM barrel domain; PEP-utilising enzyme, N-terminal; TIGRFAM: phosphoenolpyruvate-protein phosphotransferase YP_004414346.1 COGs: COG1925 Phosphotransferase system HPr-related protein; InterPro IPR005698; KEGG: hmo:HM1_0837 phosphocarrier protein hpr, putative; PFAM: Phosphotransferase system, phosphocarrier HPr protein; SPTR: Phosphocarrier protein HPr; TIGRFAM: Phosphotransferase system, phosphocarrier HPr protein; IMG reference gene:2504587429; PFAM: PTS HPr component phosphorylation site; TIGRFAM: Phosphotransferase System HPr (HPr) Family YP_004414347.1 KEGG: cth:Cthe_1890 cellulosome enzyme, dockerin type I; SPTR: Cellulosome enzyme, dockerin type I; IMG reference gene:2504587430 YP_004414348.1 COGs: COG3881 conserved hypothetical protein; InterPro IPR007903; KEGG: hmo:HM1_0107 prc-barrel, putative; PFAM: PRC-barrel; SPTR: Putative PRC-barrel domain protein; IMG reference gene:2504587431; PFAM: PRC-barrel domain YP_004414349.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587432 YP_004414350.1 KEGG: blj:BLD_1093 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504587433; TIGRFAM: small redox-active disulfide protein 2 YP_004414351.1 SPTR: Putative uncharacterized protein; manually curated; IMG reference gene:2504587434 YP_004414352.1 COGs: COG0701 permease; InterPro IPR005524; KEGG: blj:BLD_1092 hypothetical permease; PFAM: Protein of unknown function DUF318, transmembrane; SPTR: Permease family protein; IMG reference gene:2504587435; PFAM: Predicted permease YP_004414353.1 COGs: COG0640 transcriptional regulator protein; InterPro IPR001845; KEGG: dae:Dtox_4284 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Arsenical resistance operon repressor; IMG reference gene:2504587436; PFAM: Bacterial regulatory protein, arsR family YP_004414354.1 KEGG: ere:EUBREC_0928 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587437; TIGRFAM: conserved hypothetical protein (putative transposase or invertase) YP_004414355.1 COGs: COG0225 Peptide methionine sulfoxide reductase; InterPro IPR002569:IPR002579; KEGG: amu:Amuc_0906 methionine-R-sulfoxide reductase; PFAM: Peptide methionine sulphoxide reductase MsrA; Methionine sulphoxide reductase B; PRIAM: Peptide-methionine (S)-S-oxide reductase., Peptide-methionine (R)-S-oxide reductase; SPTR: Peptide-methionine (S)-S-oxide reductase; TIGRFAM: Methionine sulphoxide reductase B; Peptide methionine sulphoxide reductase MsrA; IMG reference gene:2504587438; PFAM: SelR domain; Peptide methionine sulfoxide reductase; TIGRFAM: methionine-S-sulfoxide reductase; methionine-R-sulfoxide reductase YP_004414356.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: eel:EUBELI_20169 trk system potassium uptake protein TrkH; PFAM: Cation transporter; PRIAM: H(+)-transporting two-sector ATPase; SPTR: Potassium uptake protein KtrB; IMG reference gene:2504587439; PFAM: Cation transport protein; TIGRFAM: potassium uptake protein, TrkH family YP_004414357.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR006037:IPR003148; KEGG: eel:EUBELI_20168 trk system potassium uptake protein TrkA; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Potassium uptake protein KtrA; IMG reference gene:2504587440; PFAM: TrkA-N domain; TrkA-C domain YP_004414358.1 InterPro IPR000160; KEGG: cbt:CLH_2034 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor; PFAM: Diguanylate cyclase, predicted; SPTR: Putative GGDEF domain protein; IMG reference gene:2504587442; PFAM: GGDEF domain YP_004414359.1 COGs: COG0822 NifU homolog involved in Fe-S cluster formation; InterPro IPR011341:IPR002871; KEGG: vpr:Vpar_1027 SUF system FeS assembly protein, NifU family; PFAM: NIF system FeS cluster assembly, NifU, N-terminal; SPTR: SUF system FeS assembly protein, NifU family; TIGRFAM: SUF system FeS cluster assembly, SufU scaffold; IMG reference gene:2504587443; PFAM: NifU-like N terminal domain; TIGRFAM: SUF system FeS assembly protein, NifU family YP_004414360.1 COGs: COG0520 Selenocysteine lyase; InterPro IPR010970:IPR000192; KEGG: cac:CA_C3291 selenocysteine lyase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Selenocysteine lyase; SPTR: Cysteine desulfurase; TIGRFAM: Cysteine desulfurase, SufS; IMG reference gene:2504587444; PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurases, SufS subfamily YP_004414361.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR000825; KEGG: cac:CA_C3290 iron-regulated ABC-type transporter membrane component (SufB); PFAM: SUF system FeS cluster assembly, SufBD; SPTR: Iron-regulated ABC-type transporter membrane component; IMG reference gene:2504587445; PFAM: Uncharacterized protein family (UPF0051) YP_004414362.1 COGs: COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component; InterPro IPR010231:IPR000825; KEGG: cac:CA_C3289 iron-regulated ABC-type transporter membrane component (SufB); PFAM: SUF system FeS cluster assembly, SufBD; SPTR: FeS assembly protein SufB; TIGRFAM: SUF system FeS cluster assembly, SufB; IMG reference gene:2504587446; PFAM: Uncharacterized protein family (UPF0051); TIGRFAM: FeS assembly protein SufB YP_004414363.1 COGs: COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component; InterPro IPR010230:IPR003593:IPR003439; KEGG: cac:CA_C3288 iron-regulated ABC transporter ATPase; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: FeS assembly ATPase SufC; TIGRFAM: ATPase SufC, SUF system FeS cluster assembly; IMG reference gene:2504587447; PFAM: ABC transporter; TIGRFAM: FeS assembly ATPase SufC YP_004414364.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: amt:Amet_3141 two component LuxR family transcriptional regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: DNA-binding response regulator DegU; IMG reference gene:2504587448; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004414365.1 COGs: COG1450 Type II secretory pathway component PulD; InterPro IPR011662:IPR004846; KEGG: afn:Acfer_0509 type II and III secretion system protein; PFAM: Type II/III secretion system; Secretin/TonB, short N-terminal; SMART: Secretin/TonB, short N-terminal; SPTR: Putative secretin and TonB short domain protein; IMG reference gene:2504587449; PFAM: Bacterial type II/III secretion system short domain; Bacterial type II and III secretion system protein YP_004414366.1 SPTR: Putative membrane protein; IMG reference gene:2504587450 YP_004414367.1 COGs: COG0166 Glucose-6-phosphate isomerase; InterPro IPR001672; KEGG: vpr:Vpar_0658 phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2504587451; PFAM: Phosphoglucose isomerase YP_004414368.1 COGs: COG1210 UDP-glucose pyrophosphorylase; InterPro IPR005835:IPR005771; KEGG: cpf:CPF_0483 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: UTP--glucose-1-phosphate uridylyltransferase; SPTR: UTP-glucose-1-phosphate uridylyltransferase; TIGRFAM: UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal type; IMG reference gene:2504587452; PFAM: Nucleotidyl transferase; TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase YP_004414369.1 COGs: COG1109 Phosphomannomutase; InterPro IPR005846:IPR005845:IPR005844:IPR005843; KEGG: dae:Dtox_0895 phosphomannomutase; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, C-terminal; SPTR: Phosphomannomutase; IMG reference gene:2504587453; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I YP_004414370.1 COGs: COG1706 Flagellar basal-body P-ring protein; InterPro IPR001782; KEGG: aar:Acear_2205 flagellar P-ring protein; PFAM: Flagellar P-ring protein; SPTR: Flagellar P-ring protein; IMG reference gene:2504587455; PFAM: Flagellar P-ring protein YP_004414371.1 COGs: COG2063 Flagellar basal body L-ring protein; InterPro IPR000527; KEGG: tai:Taci_1145 flagellar L-ring protein; PFAM: Flagellar L-ring protein; SPTR: Flagellar L-ring protein FlgH; IMG reference gene:2504587456; PFAM: Flagellar L-ring protein YP_004414372.1 COGs: COG1261 Flagellar basal body P-ring biosynthesis protein; InterPro IPR013974:IPR017585; KEGG: geo:Geob_0629 flagella basal body P-ring formation protein FlgA; PFAM: SAF domain; SMART: SAF domain; SPTR: Putative flagella basal body P-ring formation protein FlgA; TIGRFAM: Flagella basal body P-ring formation protein FlgA; IMG reference gene:2504587457; PFAM: SAF domain; TIGRFAM: flagella basal body P-ring formation protein FlgA YP_004414373.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR010930:IPR020013:IPR012834:IPR001444; KEGG: tai:Taci_1147 flagellar basal-body rod protein FlgG; PFAM: Domain of unknown function DUF1078, C-terminal; Flagellar basal body rod protein, N-terminal; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: Flagellar basal-body rod FlgG; Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504587458; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: fagellar hook-basal body proteins; flagellar basal-body rod protein FlgG, Gram-negative bacteria YP_004414374.1 COGs: COG4786 Flagellar basal body rod protein; InterPro IPR010930:IPR020013:IPR001444; KEGG: tjr:TherJR_2882 flagellar basal-body rod protein FlgF; PFAM: Flagellar basal body rod protein, N-terminal; Domain of unknown function DUF1078, C-terminal; SPTR: Flagellar basal-body rod protein FlgG; TIGRFAM: Fagellar hook-basal body protein, FlgE/F/G; IMG reference gene:2504587459; PFAM: Flagella basal body rod protein; Domain of unknown function (DUF1078); TIGRFAM: fagellar hook-basal body proteins YP_004414375.1 COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: cth:Cthe_2619 rod shape-determining protein Mbl; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Mbl protein; TIGRFAM: Cell shape determining protein MreB/Mrl; IMG reference gene:2504587460; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family YP_004414376.1 SPTR: Putative keto/oxoacid ferredoxin oxidoreductase, delta subunit; IMG reference gene:2504587461 YP_004414377.1 COGs: COG0503 Adenine/guanine phosphoribosyltransferase and related PRPP-binding protein; InterPro IPR000836; KEGG: afn:Acfer_1856 phosphoribosyltransferase; PFAM: Phosphoribosyltransferase; SPTR: Adenine phosphoribosyltransferase; IMG reference gene:2504587481; PFAM: Phosphoribosyl transferase domain YP_004414378.1 COGs: COG3875 conserved hypothetical protein; InterPro IPR018657; KEGG: vpr:Vpar_0984 hypothetical protein; PFAM: Protein of unknown function DUF2088; SPTR: Putative transcriptional regulator; IMG reference gene:2504587482; PFAM: Uncharacterized conserved protein (DUF2088) YP_004414379.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587483 YP_004414380.1 SPTR: 50S ribosomal protein L21; IMG reference gene:2504587484 YP_004414381.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587485 YP_004414382.1 IMG reference gene:2504587488 YP_004414383.1 IMG reference gene:2504587489 YP_004414384.1 COGs: COG1343 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR021127:IPR019199; KEGG: afn:Acfer_0762 CRISPR-associated protein Cas2; PFAM: Virulence-associated protein D / CRISPR associated protein Cas2; SPTR: CRISPR-associated protein Cas2; TIGRFAM: CRISPR associated protein Cas2; IMG reference gene:2504587490; PFAM: CRISPR associated protein Cas2; TIGRFAM: CRISPR-associated endoribonuclease Cas2 YP_004414385.1 COGs: COG1518 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR019856:IPR002729; KEGG: ele:Elen_1974 CRISPR-associated protein Cas1; PFAM: CRISPR-associated protein Cas1; SPTR: CRISPR-associated protein Cas1; TIGRFAM: CRISPR-associated protein Cas1, DVULG subtype; CRISPR-associated protein Cas1; IMG reference gene:2504587491; PFAM: CRISPR associated protein Cas1; TIGRFAM: CRISPR-associated endonuclease Cas1, subtype I-C/DVULG; CRISPR-associated endonuclease Cas1 YP_004414386.1 COGs: COG1468 RecB family exonuclease; InterPro IPR013343:IPR022765; KEGG: dae:Dtox_3647 CRISPR-associated protein Cas4; PFAM: Dna2/Cas4, domain of unknown function DUF83; SPTR: CRISPR-associated protein Cas4; TIGRFAM: CRISPR-associated protein Cas4; IMG reference gene:2504587492; PFAM: Domain of unknown function DUF83; TIGRFAM: CRISPR-associated protein Cas4 YP_004414387.1 COGs: COG3649 Uncharacterized protein predicted to be involved in DNA repair; InterPro IPR013418:IPR006482; KEGG: afn:Acfer_0759 CRISPR-associated protein, Csd2 family; PFAM: CRISPR-associated protein TM1801; SPTR: CRISPR-associated protein, Csd2 family; TIGRFAM: CRISPR-associated protein Csd2; CRISPR-associated protein TM1801; IMG reference gene:2504587493; PFAM: Family of unknown function (DUF694); TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein Cas7/Csd2, subtype I-C/DVULG YP_004414388.1 InterPro IPR010144; KEGG: afn:Acfer_0758 CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein, Csd1-type; SPTR: CRISPR-associated protein, Csd1 family; TIGRFAM: CRISPR-associated protein, Csd1-type; manually curated; IMG reference gene:2504587494; PFAM: CRISPR-associated protein (Cas_Csd1); TIGRFAM: CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG YP_004414389.1 InterPro IPR013422:IPR021124:IPR010155; KEGG: afn:Acfer_0757 CRISPR-associated protein Cas5 family; PFAM: CRISPR-associated protein, Cas5; SPTR: CRISPR-associated protein Cas5, Dvulg subtype; TIGRFAM: CRISPR-associated protein, Cas5d-type; CRISPR-associated protein Cas5, N-terminal domain; IMG reference gene:2504587495; PFAM: CRISPR-associated protein (Cas_Cas5); TIGRFAM: CRISPR-associated protein Cas5, subtype I-C/DVULG; CRISPR-associated protein Cas5, N-terminal domain YP_004414390.1 COGs: COG1203 helicase; InterProIPR011545:IPR006483:IPR006474:IPR003607:IPR 014001:IPR006674; KEGG: afn:Acfer_0756 metal dependent phosphohydrolase; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Metal-dependent phosphohydrolase, HD subdomain; SMART: DEAD-like helicase, N-terminal; Metal-dependent phosphohydrolase, HD domain; SPTR: CRISPR-associated helicase Cas3; TIGRFAM: CRISPR-associated HD domain; Helicase Cas3, CRISPR-associated, core; IMG reference gene:2504587496; PFAM: HD domain; DEAD/DEAH box helicase; TIGRFAM: CRISPR-associated helicase Cas3; CRISPR-associated endonuclease Cas3-HD YP_004414391.1 COGs: COG1451 metal-dependent hydrolase; InterPro IPR002725; KEGG: nhl:Nhal_1045 protein of unknown function DUF45; PFAM: Protein of unknown function DUF45; SPTR: Phosphonate metabolism protein PhnI; IMG reference gene:2504587497; PFAM: Protein of unknown function DUF45 YP_004414392.1 COGs: COG0188 Type IIA topoisomerase (DNA gyrase/topo II topoisomerase IV) A subunit; InterPro IPR002205:IPR005743:IPR006691; KEGG: tjr:TherJR_0009 DNA gyrase, A subunit; PFAM: DNA topoisomerase, type IIA, subunit A/C-terminal; DNA gyrase/topoisomerase IV, subunit A, C-terminal beta-pinwheel; PRIAM: DNA topoisomerase (ATP-hydrolyzing); SMART: DNA topoisomerase, type IIA, subunit A/C-terminal; SPTR: DNA gyrase, A subunit; TIGRFAM: DNA gyrase, subunit A; IMG reference gene:2504587498; PFAM: DNA gyrase/topoisomerase IV, subunit A; DNA gyrase C-terminal domain, beta-propeller; TIGRFAM: DNA gyrase, A subunit YP_004414393.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504587499 YP_004414394.1 COGs: COG1281 Disulfide bond chaperones of the HSP33 family; InterPro IPR000397; KEGG: drm:Dred_1343 HSP33 protein; PFAM: Heat shock protein Hsp33 protein; SPTR: 33 kDa chaperonin; IMG reference gene:2504587500; PFAM: Hsp33 protein YP_004414395.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587501 YP_004414396.1 KEGG: hso:HS_0447 hypothetical protein; SPTR: Toxin-antitoxin system protein; IMG reference gene:2504587502 YP_004414397.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR012753:IPR007712; KEGG: sss:SSUSC84_1348 plasmid stabilisation system protein; PFAM: Plasmid stabilisation system; SPTR: Toxin-antitoxin system, toxin component, RelE family; TIGRFAM: Addiction module toxin, RelE/StbE; IMG reference gene:2504587503; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004414398.1 COGs: COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB); InterPro IPR011611:IPR022463:IPR017583; KEGG: elm:ELI_1088 hypothetical protein; PFAM: Carbohydrate/purine kinase; PRIAM: 1-phosphofructokinase; SPTR: 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; Tagatose/fructose phosphokinase; IMG reference gene:2504587504; PFAM: pfkB family carbohydrate kinase; TIGRFAM: 1-phosphofructokinase; hexose kinase, 1-phosphofructokinase family YP_004414399.1 COGs: COG1299 Phosphotransferase system fructose-specific IIC component; InterProIPR006327:IPR004715:IPR003501:IPR003352:IPR 002178:IPR003353; KEGG: vpr:Vpar_1578 PTS system, fructose subfamily, IIC subunit; PFAM: Phosphotransferase system, phosphoenolpyruvate-dependent sugar EIIA 2; Phosphotransferase system, EIIC; Phosphotransferase system, EIIB component, type 2/3; SPTR: PTS system, fructose-specific IIABC component; TIGRFAM: Phosphotransferase system, fructose IIC component; Phosphotransferase system, IIA component fructose subfamily; Phosphotransferase system, fructose-specific IIB subunit; IMG reference gene:2504587505; PFAM: Phosphotransferase system, EIIC; PTS system, Lactose/Cellobiose specific IIB subunit; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; TIGRFAM: PTS system, fructose-specific, IIB component; PTS system, fructose subfamily, IIC component; PTS system, fructose subfamily, IIA component YP_004414400.1 InterPro IPR001845; KEGG: afn:Acfer_0809 transcriptional regulator, ArsR family; PFAM: HTH transcriptional regulator, ArsR; SMART: HTH transcriptional regulator, ArsR; SPTR: Transcriptional regulator, ArsR family; IMG reference gene:2504587506; PFAM: Bacterial regulatory protein, arsR family YP_004414401.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587507 YP_004414402.1 COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034:IPR004550; KEGG: bpr:GBP346_A2376 L-asparaginase (L-asparagine amidohydrolase) (L-ASNase); PFAM: Asparaginase/glutaminase; PRIAM: Asparaginase; SMART: Asparaginase/glutaminase; SPTR: L-asparaginase; TIGRFAM: L-asparaginase, type II; IMG reference gene:2504587508; PFAM: Asparaginase; TIGRFAM: L-asparaginases, type II YP_004414403.1 InterPro IPR011112:IPR012912; KEGG: csh:Closa_0369 plasmid pRiA4b ORF-3 family protein; PFAM: Plasmid pRiA4b ORF-3-like; Rho termination factor, N-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504587509; PFAM: Plasmid pRiA4b ORF-3-like protein; Rho termination factor, N-terminal domain YP_004414404.1 COGs: COG0012 GTPase probable translation factor; InterPro IPR004396:IPR002917:IPR013029; KEGG: afn:Acfer_0140 GTP-binding protein YchF; PFAM: Domain of unknown function DUF933; GTP-binding protein, HSR1-related; SPTR: GTP-binding protein YchF; TIGRFAM: Conserved hypothetical protein CHP00092; IMG reference gene:2504587510; PFAM: GTPase of unknown function; Protein of unknown function (DUF933); TIGRFAM: GTP-binding protein YchF YP_004414405.1 InterPro IPR011701; KEGG: drm:Dred_0599 major facilitator transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Major facilitator family protein; IMG reference gene:2504587511; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily YP_004414406.1 COGs: COG4481 conserved hypothetical protein; InterPro IPR009296; KEGG: afn:Acfer_0021 protein of unknown function DUF951; PFAM: Protein of unknown function DUF951; SPTR: Putative uncharacterized protein; IMG reference gene:2504587512; PFAM: Bacterial protein of unknown function (DUF951) YP_004414407.1 COGs: COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain; InterPro IPR000673; KEGG: cbe:Cbei_4826 response regulator receiver modulated CheB methylesterase; PFAM: Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase; PRIAM: Protein-glutamate methylesterase; SPTR: Chemotaxis response regulator protein-glutamate methylesterase; manually curated; IMG reference gene:2504587513; PFAM: CheB methylesterase YP_004414408.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587514 YP_004414409.1 COGs: COG2323 membrane protein; InterPro IPR007353; KEGG: vpr:Vpar_1434 protein of unknown function DUF421; PFAM: Protein of unknown function DUF421; SPTR: Putative membrane protein; IMG reference gene:2504587516; PFAM: Protein of unknown function (DUF421) YP_004414410.1 KEGG: aap:NT05HA_1252 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587517; PFAM: Protein of unknown function (DUF3290) YP_004414411.1 COGs: COG1108 ABC-type Mn2+/Zn2+ transport systems permease components; InterPro IPR001626; KEGG: cpy:Cphy_3489 ABC-3 protein; PFAM: ABC-3; SPTR: Putative cation ABC transporter, permease protein; IMG reference gene:2504587518; PFAM: ABC 3 transport family YP_004414412.1 COGs: COG1121 ABC-type Mn/Zn transport systems ATPase component; InterPro IPR003593:IPR003439; KEGG: cce:Ccel_3414 ABC transporter related; PFAM: ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: Zinc import ATP-binding protein ZnuC; IMG reference gene:2504587519; PFAM: ABC transporter YP_004414413.1 InterPro IPR013525; KEGG: adg:Adeg_0558 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: ABC-2 transporter, permease protein; IMG reference gene:2504587520; PFAM: ABC-2 type transporter YP_004414414.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: adg:Adeg_0557 daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504587521; PFAM: ABC transporter YP_004414415.1 COGs: COG1397 ADP-ribosylglycohydrolase; InterPro IPR005502; KEGG: cth:Cthe_2755 ADP-ribosylation/crystallin J1; PFAM: ADP-ribosylation/Crystallin J1; SPTR: ADP-ribosylglycohydrolase family protein; IMG reference gene:2504587522; PFAM: ADP-ribosylglycohydrolase YP_004414416.1 COGs: COG2110 phosphatase homologous to the C-terminal domain of histone macroH2A1; InterPro IPR002589; KEGG: tde:TDE0674 hypothetical protein; PFAM: Appr-1-p processing; SMART: Appr-1-p processing; SPTR: Appr-1-p processing enzyme family domain protein; IMG reference gene:2504587523; PFAM: Macro domain YP_004414417.1 COGs: COG0846 NAD-dependent protein deacetylase SIR2 family; KEGG: ols:Olsu_0253 hypothetical protein; SPTR: SIR2 family protein; IMG reference gene:2504587524 YP_004414418.1 COGs: COG1125 ABC-type proline/glycine betaine transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: ols:Olsu_0637 ABC transporter related protein; PFAM: ABC transporter-like; PRIAM: Polyamine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Glycine betaine/L-proline ABC transporter, ATP-binding protein; IMG reference gene:2504587525; PFAM: ABC transporter YP_004414419.1 COGs: COG1732 Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein); InterPro IPR007210:IPR000515; KEGG: ols:Olsu_0636 substrate-binding region of ABC-type glycine betaine transport system; PFAM: ABC-type glycine betaine transport system, substrate-binding domain; Binding-protein-dependent transport systems inner membrane component; SPTR: Glycine betaine/L-proline ABC transporter, permease/glycine betaine/L-proline-binding protein; IMG reference gene:2504587526; PFAM: Binding-protein-dependent transport system inner membrane component; Substrate binding domain of ABC-type glycine betaine transport system YP_004414420.1 COGs: COG5015 conserved hypothetical protein; InterPro IPR011576; KEGG: mac:MA0739 hypothetical protein; PFAM: Pyridoxamine 5'-phosphate oxidase-like, FMN-binding domain; SPTR: Putative 4Fe-4S binding domain protein; IMG reference gene:2504587527; PFAM: Pyridoxamine 5'-phosphate oxidase YP_004414421.1 COGs: COG1609 Transcriptional regulators; InterPro IPR000843:IPR001761; KEGG: cbe:Cbei_5011 periplasmic binding protein/LacI transcriptional regulator; PFAM: Periplasmic binding protein/LacI transcriptional regulator; HTH transcriptional regulator, LacI; SMART: HTH transcriptional regulator, LacI; SPTR: Sucrose operon repressor; IMG reference gene:2504587528; PFAM: Bacterial regulatory proteins, lacI family; family YP_004414422.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR006232:IPR013148:IPR001362; KEGG: cbe:Cbei_5010 sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolases family 32, N-terminal; PRIAM: Beta-fructofuranosidase; SMART: Glycoside hydrolase, family 32; SPTR: Sucrose-6-phosphate hydrolase; TIGRFAM: Sucrose-6-phosphate hydrolase; IMG reference gene:2504587529; PFAM: Glycosyl hydrolases family 32 N-terminal domain; TIGRFAM: sucrose-6-phosphate hydrolase YP_004414423.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR001127:IPR010973:IPR018113:IPR003352; KEGG: cbe:Cbei_5012 PTS system, sucrose-specific IIBC subunit; PFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site; Phosphotransferase system, EIIC; PRIAM: Protein-N(pi)-phosphohistidine--sugar phosphotransferase; SPTR: PTS system, sucrose-specific IIBC component; TIGRFAM: Phosphotransferase system, sucrose-specific IIBC component; Phosphotransferase system, sugar-specific permease EIIA 1 domain; IMG reference gene:2504587530; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, sucrose-specific IIBC component; PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component YP_004414424.1 COGs: COG1151 6Fe-6S prismane cluster-containing protein; InterPro IPR010047:IPR004137; KEGG: vpr:Vpar_0209 carbon-monoxide dehydrogenase, catalytic subunit; PFAM: Prismane; PRIAM: Carbon-monoxide dehydrogenase (acceptor); SPTR: Carbon-monoxide dehydrogenase, catalytic subunit; TIGRFAM: Carbon-monoxide dehydrogenase, catalytic subunit; IMG reference gene:2504587531; PFAM: Prismane/CO dehydrogenase family; TIGRFAM: carbon-monoxide dehydrogenase, catalytic subunit YP_004414425.1 COGs: COG0715 ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components; InterPro IPR015168; KEGG: vpr:Vpar_1690 twin-arginine translocation pathway signal; SPTR: NLPA lipoprotein; IMG reference gene:2504587532; PFAM: NMT1/THI5 like YP_004414426.1 COGs: COG0600 ABC-type nitrate/sulfonate/bicarbonate transport system permease component; InterPro IPR000515; KEGG: vpr:Vpar_1689 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Taurine ABC transporter, permease protein; IMG reference gene:2504587533; PFAM: Binding-protein-dependent transport system inner membrane component YP_004414427.1 COGs: COG1116 ABC-type nitrate/sulfonate/bicarbonate transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cce:Ccel_0435 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Taurine-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Nitrate ABC transporter, ATP-binding protein NtrD; IMG reference gene:2504587534; PFAM: ABC transporter YP_004414428.1 KEGG: ccv:CCV52592_1956 flavodoxin; SPTR: Putative uncharacterized protein; IMG reference gene:2504587535 YP_004414429.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006236:IPR006139:IPR006140:IPR002912; KEGG: pth:PTH_0012 D-3-phosphoglycerate dehydrogenase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; Amino acid-binding ACT; PRIAM: Phosphoglycerate dehydrogenase; SPTR: Phosphoglycerate dehydrogenase; TIGRFAM: D-3-phosphoglycerate dehydrogenase; IMG reference gene:2504587536; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; ACT domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; TIGRFAM: D-3-phosphoglycerate dehydrogenase YP_004414430.1 COGs: COG1932 Phosphoserine aminotransferase; HAMAP: Phosphoserine aminotransferase; InterPro IPR003248:IPR000192:IPR022278; KEGG: hmo:HM1_2036 phosphoserine aminotransferase; PFAM: Aminotransferase, class V/Cysteine desulfurase; PRIAM: Phosphoserine transaminase; SPTR: Phosphoserine aminotransferase; TIGRFAM: Phosphoserine aminotransferase, subgroup; IMG reference gene:2504587537; PFAM: Aminotransferase class-V; TIGRFAM: phosphoserine aminotransferase YP_004414431.1 KEGG: vpr:Vpar_0419 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587538 YP_004414432.1 COGs: COG1655 conserved hypothetical protein; InterPro IPR018708; KEGG: cth:Cthe_1061 hypothetical protein; PFAM: Protein of unknown function DUF2225; SPTR: Putative uncharacterized protein; IMG reference gene:2504587539; PFAM: Uncharacterized protein conserved in bacteria (DUF2225) YP_004414433.1 COGs: COG1640 4-alpha-glucanotransferase; InterPro IPR006589:IPR003385:IPR006047; KEGG: nth:Nther_0557 putative bifunctional 4-alpha-glucanotransferase/glycogen debranching enzyme; PFAM: Glycoside hydrolase, family 77; Glycosyl hydrolase, family 13, catalytic domain; PRIAM: Pullulanase., 4-alpha-glucanotransferase; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: 4-alpha-glucanotransferase; TIGRFAM: Glycoside hydrolase, family 77; IMG reference gene:2504587540; PFAM: 4-alpha-glucanotransferase; Alpha amylase, catalytic domain; TIGRFAM: 4-alpha-glucanotransferase YP_004414434.1 COGs: COG0297 Glycogen synthase; HAMAP: Glycogen/starch synthases, ADP-glucose type; InterPro IPR011835:IPR013534:IPR001296; KEGG: dae:Dtox_0821 glycogen/starch synthase, ADP-glucose type; PFAM: Starch synthase, catalytic domain; Glycosyl transferase, group 1; PRIAM: Starch synthase; SPTR: Glycogen synthase; TIGRFAM: Glycogen/starch synthases, ADP-glucose type; IMG reference gene:2504587541; PFAM: Starch synthase catalytic domain; Glycosyl transferases group 1; TIGRFAM: glycogen/starch synthases, ADP-glucose type YP_004414435.1 COGs: COG0296 1 4-alpha-glucan branching enzyme; HAMAP: 1,4-alpha-glucan-branching enzyme; InterProIPR006589:IPR006407:IPR004193:IPR006047:IPR 006048; KEGG: afn:Acfer_0403 1,4-alpha-glucan branching enzyme; PFAM: Alpha-amylase, C-terminal all beta; Glycoside hydrolase, family 13, N-terminal; Glycosyl hydrolase, family 13, catalytic domain; PRIAM: 1,4-alpha-glucan branching enzyme; SMART: Glycosyl hydrolase, family 13, subfamily, catalytic domain; SPTR: 1,4-alpha-glucan-branching enzyme; TIGRFAM: 1,4-alpha-glucan-branching enzyme; IMG reference gene:2504587542; PFAM: Alpha amylase, C-terminal all-beta domain; Carbohydrate-binding module 48 (Isoamylase N-terminal domain); Alpha amylase, catalytic domain; TIGRFAM: alpha-1,4-glucan:alpha-1,4-glucan 6-glycosyltransferase YP_004414436.1 COGs: COG0058 Glucan phosphorylase; InterPro IPR011833:IPR000811; KEGG: tjr:TherJR_0908 glycogen/starch/alpha-glucan phosphorylase; PFAM: Glycosyl transferase, family 35; SPTR: Phosphorylase; TIGRFAM: Glycogen/starch/alpha-glucan phosphorylase; IMG reference gene:2504587543; PFAM: Carbohydrate phosphorylase; TIGRFAM: glycogen/starch/alpha-glucan phosphorylases YP_004414437.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR011832:IPR005835; KEGG: drm:Dred_1456 glucose-1-phosphate adenylyltransferase, GlgD subunit; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase, GlgD subunit; TIGRFAM: Glucose-1-phosphate adenylyltransferase, GlgD subunit; IMG reference gene:2504587544; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase, GlgD subunit YP_004414438.1 COGs: COG0448 ADP-glucose pyrophosphorylase; InterPro IPR005835:IPR011831; KEGG: afn:Acfer_0400 glucose-1-phosphate adenylyltransferase; PFAM: Nucleotidyl transferase; PRIAM: Glucose-1-phosphate adenylyltransferase; SPTR: Glucose-1-phosphate adenylyltransferase; TIGRFAM: Glucose-1-phosphate adenylyltransferase; IMG reference gene:2504587545; PFAM: Nucleotidyl transferase; TIGRFAM: glucose-1-phosphate adenylyltransferase YP_004414439.1 SPTR: Multiple antibiotic resistance (MarC)-related protein; IMG reference gene:2504587546 YP_004414440.1 InterPro IPR006619:IPR002502:IPR006311; KEGG: ctc:CTC_p55 putative N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase, family 2; SMART: N-acetylmuramoyl-L-alanine amidase, family 2; Peptidoglycan recognition protein, metazoa/bacteria; SPTR: Prophage LambdaCh01, N-acetylmuramoyl-L-alanine amidase; IMG reference gene:2504587547; PFAM: N-acetylmuramoyl-L-alanine amidase YP_004414441.1 COGs: COG4178 ABC-type uncharacterized transport system permease and ATPase components; InterPro IPR003593:IPR010509:IPR003439; KEGG: afn:Acfer_0248 ABC transporter domain protein; PFAM: ABC transporter, N-terminal; ABC transporter-like; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504587548; PFAM: ABC transporter; ABC transporter transmembrane region 2 YP_004414442.1 COGs: COG2227 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1 4-benzoquinol methylase; InterPro IPR013217; KEGG: cdl:CDR20291_0242 glycosyl transferase family 2; PFAM: Methyltransferase type 12; SPTR: Glycosyl transferase, group 2 family; IMG reference gene:2504587549; PFAM: Methyltransferase domain YP_004414443.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587550 YP_004414444.1 COGs: COG0833 Amino acid transporter; InterPro IPR004841; KEGG: drm:Dred_1373 amino acid permease-associated region; PFAM: Amino acid permease domain; SPTR: Lysine-specific permease; IMG reference gene:2504587551; PFAM: Amino acid permease YP_004414445.1 COGs: COG1739 conserved hypothetical protein; InterPro IPR015269:IPR001498:IPR015796; KEGG: eat:EAT1b_0944 protein of unknown function UPF0029; PFAM: Uncharacterised protein family UPF0029, Impact, N-terminal; Uncharacterised protein family UPF0029, Impact, C-terminal; SPTR: IMPACT family protein; TIGRFAM: Uncharacterised protein family UPF0029, Impact; IMG reference gene:2504587552; PFAM: Uncharacterized protein family UPF0029; Domain of unknown function (DUF1949); TIGRFAM: uncharacterized protein, YigZ family YP_004414446.1 SPTR: Molybdenum cofactor biosynthesis protein D; manually curated; IMG reference gene:2504587553 YP_004414447.1 InterPro IPR001087; KEGG: afn:Acfer_1759 hypothetical protein; PFAM: Lipase, GDSL; SPTR: Putative DNA-binding protein; IMG reference gene:2504587554 YP_004414448.1 COGs: COG1252 NADH dehydrogenase FAD-containing subunit; InterPro IPR013027:IPR001327; KEGG: lil:LB_036 NADH dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: NADH dehydrogenase (ubiquinone); SPTR: NADH dehydrogenase; IMG reference gene:2504587555; PFAM: Pyridine nucleotide-disulphide oxidoreductase YP_004414449.1 InterPro IPR004360; KEGG: afn:Acfer_0826 glyoxalase/bleomycin resistance protein/dioxygenase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Lactoylglutathione lyase; IMG reference gene:2504587556; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; TIGRFAM: lactoylglutathione lyase YP_004414450.1 COGs: COG4096 Type I site-specific restriction-modification system R (restriction) subunit and related helicase; InterPro IPR006935:IPR001650:IPR014001; KEGG: ere:EUBREC_2410 type I restriction-modification system R subunit (endonuclease); PFAM: Restriction endonuclease, type I, R subunit/Type III, Res subunit; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; SPTR: Type I restriction-modification system R subunit; IMG reference gene:2504587557; PFAM: Helicase conserved C-terminal domain; Type III restriction enzyme, res subunit YP_004414451.1 COGs: COG1253 Hemolysins and related protein containing CBS domains; InterPro IPR000644:IPR002550:IPR005170; KEGG: bts:Btus_0302 protein of unknown function DUF21; PFAM: Domain of unknown function DUF21; Cystathionine beta-synthase, core; Transporter-associated domain; SMART: Cystathionine beta-synthase, core; SPTR: CBS domain protein; IMG reference gene:2504587558; PFAM: CBS domain; Domain of unknown function DUF21; Transporter associated domain YP_004414452.1 COGs: COG0550 Topoisomerase IA; InterProIPR006171:IPR003601:IPR003602:IPR005738:IPR 013497:IPR013498; KEGG: vpr:Vpar_0629 DNA topoisomerase III; PFAM: DNA topoisomerase, type IA, central; Toprim domain; DNA topoisomerase, type IA, zn finger; PRIAM: DNA topoisomerase; SMART: DNA topoisomerase, type IA, DNA-binding; DNA topoisomerase, type IA, domain 2; Toprim domain; SPTR: DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacterial-type; IMG reference gene:2504587559; PFAM: Toprim domain; Topoisomerase DNA binding C4 zinc finger; DNA topoisomerase; TIGRFAM: DNA topoisomerase III, bacteria and conjugative plasmid YP_004414453.1 COGs: COG0019 Diaminopimelate decarboxylase; InterPro IPR022644:IPR022643; KEGG: dhd:Dhaf_4876 diaminopimelate decarboxylase; PFAM: Orn/DAP/Arg decarboxylase 2, N-terminal; Orn/DAP/Arg decarboxylase 2, C-terminal; PRIAM: Diaminopimelate decarboxylase; SPTR: Diaminopimelate decarboxylase; IMG reference gene:2504587560; PFAM: Pyridoxal-dependent decarboxylase, C-terminal sheet domain; Pyridoxal-dependent decarboxylase, pyridoxal binding domain; TIGRFAM: diaminopimelate decarboxylase YP_004414454.1 SPTR: Putative NA+/H+ antiporter NHAC; IMG reference gene:2504587562 YP_004414455.1 COGs: COG0717 Deoxycytidine deaminase; InterPro IPR008180; KEGG: hya:HY04AAS1_0561 deoxycytidine triphosphate deaminase; PFAM: DeoxyUTP pyrophosphatase domain; SPTR: Putative deoxycytidine triphosphate deaminase; IMG reference gene:2504587563; PFAM: dUTPase; TIGRFAM: deoxycytidine triphosphate deaminase YP_004414456.1 COGs: COG4241 membrane protein; InterPro IPR018710; KEGG: aco:Amico_1419 protein of unknown function DUF2232, membrane; PFAM: Protein of unknown function DUF2232, membrane; SPTR: Putative uncharacterized protein; IMG reference gene:2504587565; PFAM: Predicted membrane protein (DUF2232) YP_004414457.1 COGs: COG3887 signaling protein consisting of a modified GGDEF domain and a DHH domain; InterPro IPR000160:IPR001667:IPR003156; KEGG: afn:Acfer_0042 diguanylate cyclase and phosphoesterase; PFAM: Phosphoesterase, RecJ-like; Diguanylate cyclase, predicted; Phosphoesterase, DHHA1; SMART: Diguanylate cyclase, predicted; SPTR: DHH family protein; IMG reference gene:2504587566; PFAM: DHHA1 domain; DHH family; GGDEF domain YP_004414458.1 COGs: COG0359 Ribosomal protein L9; InterPro IPR020594:IPR020069:IPR020070; KEGG: vpr:Vpar_1682 ribosomal protein L9; PFAM: Ribosomal protein L9, C-terminal; Ribosomal protein L9, N-terminal; SPTR: 50S ribosomal protein L9; TIGRFAM: Ribosomal protein L9, bacteria/chloroplast; IMG reference gene:2504587567; PFAM: Ribosomal protein L9, N-terminal domain; Ribosomal protein L9, C-terminal domain; TIGRFAM: ribosomal protein L9 YP_004414459.1 COGs: COG1067 ATP-dependent protease; InterPro IPR008269:IPR003593:IPR003959:IPR014252; KEGG: drm:Dred_3302 endopeptidase La; PFAM: Peptidase S16, Lon C-terminal; ATPase, AAA-type, core; PRIAM: Endopeptidase La; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent protease, Lon family; TIGRFAM: Sporulation protease LonC; IMG reference gene:2504587568; PFAM: ATPase family associated with various cellular activities (AAA); Lon protease (S16) C-terminal proteolytic domain; TIGRFAM: lon-related putative ATP-dependent protease; ATP-dependent protease, Lon family YP_004414460.1 COGs: COG0305 Replicative DNA helicase; InterPro IPR007694:IPR007693:IPR007692; KEGG: tjr:TherJR_2972 replicative DNA helicase; PFAM: DNA helicase, DnaB-like, C-terminal; DNA helicase, DnaB-like, N-terminal; SPTR: Replicative DNA helicase; TIGRFAM: DNA helicase, DnaB type; IMG reference gene:2504587569; PFAM: DnaB-like helicase N terminal domain; DnaB-like helicase C terminal domain; TIGRFAM: replicative DNA helicase YP_004414461.1 COGs: COG1621 Beta-fructosidase (levanase/invertase); InterPro IPR013148:IPR001362; KEGG: cbt:CLH_3235 sucrose-6-phosphate hydrolase; PFAM: Glycosyl hydrolases family 32, N-terminal; PRIAM: Beta-fructofuranosidase; SMART: Glycoside hydrolase, family 32; SPTR: Sucrose-6-phosphate dehydrogenase; IMG reference gene:2504587570; PFAM: Glycosyl hydrolases family 32 N-terminal domain YP_004414462.1 COGs: COG0492 Thioredoxin reductase; InterPro IPR013027:IPR001327:IPR017561; KEGG: apv:Apar_0907 thioredoxin-disulfide reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region; PRIAM: Thioredoxin-disulfide reductase; SPTR: Putative alkyl hydroperoxide reductase F subunit; TIGRFAM: Putative alkyl hydroperoxide reductase F subunit; IMG reference gene:2504587571; PFAM: Pyridine nucleotide-disulphide oxidoreductase; TIGRFAM: putative alkyl hydroperoxide reductase F subunit; thioredoxin-disulfide reductase YP_004414463.1 COGs: COG0450 Peroxiredoxin; InterPro IPR017559:IPR019479:IPR000866; KEGG: ccu:Ccur_01110 peroxiredoxin; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; Peroxiredoxin, C-terminal; PRIAM: Peroxiredoxin; SPTR: Peroxiredoxin; TIGRFAM: Peroxiredoxin; IMG reference gene:2504587572; PFAM: C-terminal domain of 1-Cys peroxiredoxin; AhpC/TSA family; TIGRFAM: peroxiredoxin YP_004414464.1 COGs: COG1387 Histidinol phosphatase and related hydrolase of the PHP family; InterPro IPR010140:IPR004013; KEGG: cac:CA_C2727 histidinol-phosphatase; PFAM: PHP, C-terminal; PRIAM: Histidinol-phosphatase; SPTR: Putative histidinol-phosphatase; TIGRFAM: Histidinol phosphate phosphatase, HisJ; IMG reference gene:2504587573; PFAM: PHP domain; TIGRFAM: histidinol phosphate phosphatase HisJ family YP_004414465.1 COGs: COG0030 Dimethyladenosine transferase (rRNA methylation); InterPro IPR020598:IPR011530:IPR001737; KEGG: vpr:Vpar_0626 dimethyladenosine transferase; PFAM: Ribosomal RNA adenine methylase transferase; SMART: Ribosomal RNA adenine methylase transferase, N-terminal; SPTR: Ribosomal RNA small subunit methyltransferase A; TIGRFAM: Ribosomal RNA adenine dimethylase; IMG reference gene:2504587574; PFAM: Ribosomal RNA adenine dimethylase; TIGRFAM: dimethyladenosine transferase YP_004414466.1 COGs: COG1658 Small primase-like protein (Toprim domain); InterPro IPR006171:IPR004466; KEGG: afn:Acfer_1435 primase/topoisomerase like protein; PFAM: Toprim domain; SMART: Toprim domain; SPTR: Primase-like protein; TIGRFAM: Primase-related protein; manually curated; IMG reference gene:2504587575; PFAM: Toprim domain; TIGRFAM: ribonuclease M5 YP_004414467.1 COGs: COG0125 Thymidylate kinase; HAMAP: Thymidylate kinase; InterPro IPR018094; KEGG: clj:CLJU_c01390 thymidylate kinase; PFAM: Thymidylate kinase; SPTR: dTMP kinase; IMG reference gene:2504587576; PFAM: Thymidylate kinase YP_004414468.1 COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660:IPR003594:IPR003661; KEGG: tjr:TherJR_2683 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Two component system histidine kinase; IMG reference gene:2504587577; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004414469.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: aar:Acear_1915 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: DNA-binding response regulator YycF; IMG reference gene:2504587578; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004414470.1 COGs: COG0583 Transcriptional regulator; InterPro IPR000847:IPR005119; KEGG: clj:CLJU_c42440 putative LysR family transcriptional regulator; PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; SPTR: Transcriptional regulator, LysR family; IMG reference gene:2504587579; PFAM: Bacterial regulatory helix-turn-helix protein, lysR family; LysR substrate binding domain YP_004414471.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1342 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Putative outer membrane ferric enterobactin receptor; IMG reference gene:2504587580; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004414472.1 SPTR: 60S acidic ribosomal protein P1; IMG reference gene:2504587581 YP_004414473.1 InterPro IPR005546:IPR006315; KEGG: dvm:DvMF_1880 outer membrane autotransporter barrel domain protein; PFAM: Autotransporter beta-domain; SPTR: Putative autotransporter beta-domain protein; TIGRFAM: Outer membrane autotransporter barrel; IMG reference gene:2504587582; PFAM: Autotransporter beta-domain YP_004414474.1 COGs: COG0855 Polyphosphate kinase; InterPro IPR003414; KEGG: vpr:Vpar_0620 polyphosphate kinase; PFAM: Polyphosphate kinase; PRIAM: Polyphosphate kinase; SPTR: Polyphosphate kinase; TIGRFAM: Polyphosphate kinase; IMG reference gene:2504587583; PFAM: Polyphosphate kinase; TIGRFAM: polyphosphate kinase 1 YP_004414475.1 COGs: COG0248 Exopolyphosphatase; InterPro IPR003695:IPR003607; KEGG: vpr:Vpar_0619 exopolyphosphatase-like protein; PFAM: Ppx/GppA phosphatase; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative uncharacterized protein; IMG reference gene:2504587584; PFAM: Ppx/GppA phosphatase family YP_004414476.1 COGs: COG1335 Amidase related to nicotinamidase; InterPro IPR000868; KEGG: csh:Closa_1661 isochorismatase hydrolase; PFAM: Isochorismatase-like; SPTR: Amidase; IMG reference gene:2504587585; PFAM: Isochorismatase family YP_004414477.1 COGs: COG1686 D-alanyl-D-alanine carboxypeptidase; InterPro IPR012907:IPR001967; KEGG: mta:Moth_1058 serine-type D-Ala-D-Ala carboxypeptidase; PFAM: Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal; Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; PRIAM: Serine-type D-Ala-D-Ala carboxypeptidase; SMART: Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal; SPTR: Serine-type D-Ala-D-Ala carboxypeptidase; IMG reference gene:2504587586; PFAM: D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5, C-terminal domain YP_004414478.1 InterPro IPR007159; KEGG: lic:LIC12659 putative virulence-associated protein; PFAM: Transcription regulator AbrB/SpoV, predicted; SPTR: Toxin-antitoxin system, antitoxin component, AbrB famil; manually curated; IMG reference gene:2504587587; PFAM: SpoVT / AbrB like domain YP_004414479.1 COGs: COG1487 nucleic acid-binding protein contains PIN domain; InterPro IPR002716:IPR006596; KEGG: dal:Dalk_1528 PilT protein domain protein; PFAM: PilT protein, N-terminal; SMART: Nucleotide binding protein, PINc; SPTR: Virulence associated protein C; IMG reference gene:2504587588; PFAM: PIN domain YP_004414480.1 COGs: COG5438 multitransmembrane protein; InterPro IPR012507; KEGG: nth:Nther_2866 YibE/F family protein; PFAM: YibE/F-like; SPTR: Putative membrane protein; IMG reference gene:2504587589; PFAM: YibE/F-like protein YP_004414481.1 COGs: COG2050 Uncharacterized protein possibly involved in aromatic compounds catabolism; InterPro IPR003736:IPR006683; KEGG: ccb:Clocel_3832 thioesterase superfamily protein; PFAM: Thioesterase superfamily; SPTR: Phenylacetic acid degradation-related protein; TIGRFAM: Phenylacetic acid degradation-related protein; IMG reference gene:2504587590; PFAM: Thioesterase superfamily; TIGRFAM: uncharacterized domain 1 YP_004414482.1 COGs: COG1488 Nicotinic acid phosphoribosyltransferase; InterPro IPR006405:IPR015977; KEGG: eel:EUBELI_00163 nicotinate phosphoribosyltransferase; PFAM: Nicotinate phosphoribosyltransferase-like; SPTR: Nicotinate phosphoribosyltransferase; TIGRFAM: Nicotinate phosphoribosyltransferase putative; IMG reference gene:2504587591; PFAM: Nicotinate phosphoribosyltransferase (NAPRTase) family; TIGRFAM: putative nicotinate phosphoribosyltransferase YP_004414483.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR001898; KEGG: chy:CHY_0060 anion transporter family protein; PFAM: Sodium/sulphate symporter; SPTR: 2-oxoglutarate/malate translocator; TIGRFAM: Sodium/sulphate symporter; IMG reference gene:2504587592; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_004414484.1 COGs: COG3182 Uncharacterized iron-regulated membrane protein; InterPro IPR005625; KEGG: vpr:Vpar_0602 PepSY-associated TM helix domain protein; PFAM: PepSY-associated TM helix; SPTR: Putative PepSY-associated TM helix domain protein; IMG reference gene:2504587593; PFAM: PepSY-associated TM helix YP_004414485.1 COGs: COG0601 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: elm:ELI_4374 glutathione ABC transporter; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Oligopeptide ABC transporter, permease protein AppB; IMG reference gene:2504587594; PFAM: Binding-protein-dependent transport system inner membrane component YP_004414486.1 COGs: COG1173 ABC-type dipeptide/oligopeptide/nickel transport systems permease components; InterPro IPR000515; KEGG: vpr:Vpar_0085 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: Nickel ABC transporter, permease protein; IMG reference gene:2504587595; PFAM: Binding-protein-dependent transport system inner membrane component YP_004414487.1 COGs: COG0444 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: lba:Lebu_0026 ABC transporter related; PFAM: ABC transporter-like; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Dipeptide ABC transporter, ATP-binding protein; IMG reference gene:2504587596; PFAM: ABC transporter YP_004414488.1 COGs: COG1124 ABC-type dipeptide/oligopeptide/nickel transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: cef:CE2227 putative ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Nickel-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: ABC transporter, ATP-binding protein; IMG reference gene:2504587597; PFAM: ABC transporter YP_004414489.1 COGs: COG0747 ABC-type dipeptide transport system periplasmic component; InterPro IPR000914; KEGG: vpr:Vpar_0086 extracellular solute-binding protein family 5; PFAM: Bacterial extracellular solute-binding protein, family 5; SPTR: Dipeptide-binding protein; IMG reference gene:2504587598; PFAM: Bacterial extracellular solute-binding proteins, family 5 Middle YP_004414490.1 InterPro IPR001119; KEGG: afn:Acfer_1670 S-layer domain protein; PFAM: S-layer homology domain; SPTR: Putative S-layer domain protein; IMG reference gene:2504587599; PFAM: S-layer homology domain YP_004414491.1 COGs: COG0352 Thiamine monophosphate synthase; HAMAP: Thiamine monophosphate synthase; InterPro IPR003733; KEGG: bad:BAD_1145 bifunctional protein thiEC; PFAM: Thiamine monophosphate synthase; PRIAM: Thiamine-phosphate diphosphorylase; SPTR: Thiamine-phosphate diphosphorylase; IMG reference gene:2504587600; PFAM: Thiamine monophosphate synthase/TENI; TIGRFAM: thiamine-phosphate pyrophosphorylase YP_004414492.1 COGs: COG0238 Ribosomal protein S18; HAMAP: Ribosomal protein S18; InterPro IPR001648; KEGG: afn:Acfer_0040 ribosomal protein S18; PFAM: Ribosomal protein S18; SPTR: 30S ribosomal protein S18; TIGRFAM: Ribosomal protein S18; IMG reference gene:2504587601; PFAM: Ribosomal protein S18; TIGRFAM: ribosomal protein S18 YP_004414493.1 COGs: COG0629 Single-stranded DNA-binding protein; InterPro IPR000424:IPR011344; KEGG: elm:ELI_4586 single strand DNA binding protein; PFAM: Primosome PriB/single-strand DNA-binding; SPTR: Single-stranded DNA-binding protein; TIGRFAM: Single-strand DNA-binding; IMG reference gene:2504587602; PFAM: Single-strand binding protein family; TIGRFAM: single stranded DNA-binding protein (ssb) YP_004414494.1 COGs: COG0360 Ribosomal protein S6; HAMAP: Ribosomal protein S6, plastid/chloroplast; InterPro IPR000529:IPR020814; KEGG: afn:Acfer_0038 ribosomal protein S6; PFAM: Ribosomal protein S6; SPTR: 30S ribosomal protein S6; TIGRFAM: Ribosomal protein S6; IMG reference gene:2504587603; PFAM: Ribosomal protein S6; TIGRFAM: ribosomal protein S6 YP_004414495.1 InterPro IPR010809; KEGG: bcj:BCAL0113 B-type flagellar hook-associated protein 2; PFAM: Flagellar hook-associated 2, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504587604; PFAM: Flagellar hook-associated protein 2 C-terminus YP_004414496.1 KEGG: cac:CA_C0208 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587605 YP_004414497.1 COGs: COG0696 Phosphoglyceromutase; InterPro IPR005995:IPR011258:IPR006124; KEGG: tjr:TherJR_2708 phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; PFAM: Metalloenzyme; BPG-independent PGAM, N-terminal; PRIAM: Phosphoglycerate mutase; SPTR: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; TIGRFAM: Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent; IMG reference gene:2504587606; PFAM: Metalloenzyme superfamily; BPG-independent PGAM N-terminus (iPGM_N); TIGRFAM: 2,3-bisphosphoglycerate-independent phosphoglycerate mutase YP_004414498.1 COGs: COG0149 Triosephosphate isomerase; InterPro IPR000652; KEGG: cac:CA_C0711 triosephosphate isomerase; PFAM: Triosephosphate isomerase; PRIAM: Triose-phosphate isomerase; SPTR: Triosephosphate isomerase; TIGRFAM: Triosephosphate isomerase; IMG reference gene:2504587607; PFAM: Triosephosphate isomerase; TIGRFAM: triosephosphate isomerase YP_004414499.1 COGs: COG0126 3-phosphoglycerate kinase; InterPro IPR001576; KEGG: cth:Cthe_0138 phosphoglycerate kinase; PFAM: Phosphoglycerate kinase; PRIAM: Phosphoglycerate kinase; SPTR: Phosphoglycerate kinase; IMG reference gene:2504587608; PFAM: Phosphoglycerate kinase YP_004414500.1 COGs: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; InterPro IPR020828:IPR020829:IPR006424; KEGG: bpb:bpr_I2050 glyceraldehyde-3-phosphate dehydrogenase Gap; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain; PRIAM: Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating); SMART: Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain; SPTR: Glyceraldehyde-3-phosphate dehydrogenase, type I; TIGRFAM: Glyceraldehyde-3-phosphate dehydrogenase, type I; IMG reference gene:2504587609; PFAM: Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I YP_004414501.1 KEGG: lbu:LBUL_1826 surface antigen; SPTR: Putative uncharacterized protein; IMG reference gene:2504587610 YP_004414502.1 COGs: COG3600 Uncharacterized phage-associated protein; KEGG: bln:Blon_1491 hypothetical protein; SPTR: Toxin-antitoxin system, antitoxin component, Xre family; IMG reference gene:2504587611 YP_004414503.1 KEGG: aco:Amico_1149 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587612 YP_004414504.1 KEGG: afn:Acfer_0100 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587613 YP_004414505.1 COGs: COG2176 DNA polymerase III alpha subunit (gram-positive type); InterPro IPR011708:IPR003141:IPR004013; KEGG: slp:Slip_0998 DNA polymerase III, alpha subunit; PFAM: Bacterial DNA polymerase III, alpha subunit; PHP, C-terminal; SMART: Polymerase/histidinol phosphatase, N-terminal; SPTR: DNA polymerase III, alpha subunit; IMG reference gene:2504587614; PFAM: PHP domain; Bacterial DNA polymerase III alpha subunit; TIGRFAM: DNA polymerase III, alpha chain, Gram-positive type YP_004414506.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587615 YP_004414507.1 KEGG: clj:CLJU_c36340 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587616 YP_004414508.1 COGs: COG2378 transcriptional regulator protein; KEGG: bpb:bpr_IV145 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587617 YP_004414509.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587618 YP_004414510.1 COGs: COG5002 Signal transduction histidine kinase; InterPro IPR003660:IPR003594:IPR003661; KEGG: afn:Acfer_0160 integral membrane sensor signal transduction histidine kinase; PFAM: ATPase-like, ATP-binding domain; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SPTR: Sensor histidine kinase; IMG reference gene:2504587619; PFAM: HAMP domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain YP_004414511.1 COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789:IPR001867; KEGG: elm:ELI_4390 response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Alkaline phosphatase synthesis transcriptional regulatory protein PhoP; IMG reference gene:2504587620; PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal YP_004414512.1 COGs: COG1464 ABC-type metal ion transport system periplasmic component/surface antigen; InterPro IPR004478:IPR004872; KEGG: afn:Acfer_0694 lipoprotein, YaeC family; PFAM: NLPA lipoprotein; SPTR: D-methionine-binding lipoprotein MetQ; TIGRFAM: Lipoprotein YaeC; IMG reference gene:2504587621; PFAM: NLPA lipoprotein; TIGRFAM: lipoprotein, YaeC family YP_004414513.1 COGs: COG2011 ABC-type metal ion transport system permease component; InterPro IPR000515; KEGG: afn:Acfer_1180 binding-protein-dependent transport systems inner membrane component; PFAM: Binding-protein-dependent transport systems inner membrane component; SPTR: D-methionine ABC transporter, permease protein; IMG reference gene:2504587622; PFAM: Binding-protein-dependent transport system inner membrane component YP_004414514.1 COGs: COG1135 ABC-type metal ion transport system ATPase component; InterPro IPR003593:IPR018449:IPR003439; KEGG: afn:Acfer_1179 ABC transporter related protein; PFAM: ABC transporter-like; NIL domain; PRIAM: Phosphonate-transporting ATPase; SMART: NIL domain; ATPase, AAA+ type, core; SPTR: D-methionine ABC transporter, ATP-binding protein; IMG reference gene:2504587623; PFAM: ABC transporter; NIL domain; TIGRFAM: D-methionine ABC transporter, ATP-binding protein YP_004414515.1 COGs: COG2826 Transposase and inactivated derivatives IS30 family; KEGG: sak:SAK_1545 ISSag9, transposase; SPTR: ISSag9, transposase; IMG reference gene:2504587624 YP_004414516.1 COGs: COG0038 Chloride channel protein EriC; InterPro IPR001807:IPR006037; KEGG: drm:Dred_2944 Cl-channel, voltage-gated family protein; PFAM: Chloride channel, voltage gated; Regulator of K+ conductance, C-terminal; SPTR: Chloride channel protein; IMG reference gene:2504587625; PFAM: Voltage gated chloride channel; TrkA-C domain YP_004414517.1 COGs: COG2017 Galactose mutarotase; InterPro IPR008183; KEGG: rmr:Rmar_0474 aldose 1-epimerase; PFAM: Aldose 1-epimerase; PRIAM: Aldose 1-epimerase; SPTR: Aldose 1-epimerase; IMG reference gene:2504587626; PFAM: Aldose 1-epimerase YP_004414518.1 COGs: COG2200 FOG: EAL domain; InterPro IPR001633:IPR001789:IPR000160; KEGG: elm:ELI_3413 hypothetical protein; PFAM: Diguanylate phosphodiesterase, EAL domain; Signal transduction response regulator, receiver domain; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, EAL domain; Signal transduction response regulator, receiver domain; SPTR: Putative hybrid signal transduction histidine kinase and diguanylate cyclase/phosphodiesterase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504587627; PFAM: EAL domain; GGDEF domain; Response regulator receiver domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004414519.1 COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005543:IPR005311:IPR001460; KEGG: vpr:Vpar_1520 penicillin-binding protein transpeptidase; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA; PRIAM: Peptidoglycan glycosyltransferase; SMART: PASTA; SPTR: Penicillin-binding protein; IMG reference gene:2504587628; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; PASTA domain YP_004414520.1 COGs: COG1576 conserved hypothetical protein; InterPro IPR016051:IPR003742; KEGG: vpr:Vpar_1261 protein of unknown function DUF163; PFAM: SPOUT methyltransferase, predicted; SPTR: Ribosomal RNA large subunit methyltransferase H; TIGRFAM: Ribosomal RNA large subunit methyltransferase H; IMG reference gene:2504587629; PFAM: Predicted SPOUT methyltransferase; TIGRFAM: rRNA large subunit m3Psi methyltransferase RlmH YP_004414521.1 COGs: COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain; InterPro IPR001478:IPR001254; KEGG: afn:Acfer_1792 HtrA2 peptidase; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; PRIAM: HtrA2 peptidase; SMART: PDZ/DHR/GLGF; SPTR: Putative serine protease HtrA; IMG reference gene:2504587630; PFAM: Trypsin; PDZ domain (Also known as DHR or GLGF) YP_004414522.1 KEGG: mms:mma_1168 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587631 YP_004414523.1 KEGG: afn:Acfer_0433 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587632 YP_004414524.1 InterPro IPR010652; KEGG: net:Neut_0371 hypothetical protein; PFAM: Protein of unknown function DUF1232; SPTR: Putative uncharacterized protein; IMG reference gene:2504587633; PFAM: Protein of unknown function (DUF1232) YP_004414525.1 SPTR: Putative cell division protein FtsZ; IMG reference gene:2504587634 YP_004414526.1 COGs: COG1943 Transposase and inactivated derivatives; InterPro IPR002686; KEGG: cce:Ccel_3266 transposase IS200-family protein; PFAM: Transposase IS200-like; SPTR: Transposase, IS200 family; IMG reference gene:2504587635; PFAM: Transposase IS200 like YP_004414527.1 COGs: COG2378 transcriptional regulator protein; InterPro IPR013196; KEGG: cst:CLOST_1278 hypothetical protein; SPTR: HTH domain protein; IMG reference gene:2504587636; PFAM: HTH domain YP_004414528.1 SPTR: Adhesin HecA 20-residue repeat x2; IMG reference gene:2504587637 YP_004414529.1 InterPro IPR002917; KEGG: pfo:Pfl01_2664 GTP-binding protein, HSR1-like; PFAM: GTP-binding protein, HSR1-related; SPTR: Putative uncharacterized protein; IMG reference gene:2504587638; PFAM: GTPase of unknown function YP_004414530.1 KEGG: pfo:Pfl01_2663 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587639 YP_004414531.1 SPTR: Putative cell division protein FtsZ; IMG reference gene:2504587640 YP_004414532.1 COGs: COG1690 conserved hypothetical protein; InterPro IPR001233; KEGG: cbe:Cbei_3556 hypothetical protein; PFAM: Uncharacterised protein family UPF0027; SPTR: Putative uncharacterized protein; IMG reference gene:2504587641; PFAM: Uncharacterized protein family UPF0027 YP_004414533.1 IMG reference gene:2504587642 YP_004414534.1 COGs: COG4185 conserved hypothetical protein; InterPro IPR010488; KEGG: bpb:bpr_II331 hypothetical protein; PFAM: Zeta toxin; SPTR: Putative uncharacterized protein; IMG reference gene:2504587643; PFAM: Zeta toxin YP_004414535.1 SPTR: Phosphoglucosamine mutase; IMG reference gene:2504587644 YP_004414536.1 KEGG: fsu:Fisuc_1356 von Willebrand factor type A; SPTR: Putative von Willebrand factor type A domain protein; IMG reference gene:2504587645 YP_004414537.1 KEGG: cce:Ccel_0191 Appr-1-p processing domain protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587646 YP_004414538.1 COGs: COG0501 Zn-dependent protease with chaperone function; InterPro IPR001915; KEGG: gme:Gmet_1156 HtpX-2 peptidase; PFAM: Peptidase M48; SPTR: Protease HtpX homolog; IMG reference gene:2504587647; PFAM: Peptidase family M48 YP_004414539.1 COGs: COG1966 Carbon starvation protein predicted membrane protein; InterPro IPR003706; KEGG: afn:Acfer_0616 carbon starvation protein CstA; PFAM: Carbon starvation protein CstA; SPTR: Carbon starvation-induced protein; IMG reference gene:2504587648; PFAM: Carbon starvation protein CstA YP_004414540.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587649 YP_004414541.1 KEGG: vpr:Vpar_1316 hypothetical protein; SPTR: Putative cytoplasmic protein; IMG reference gene:2504587650; PFAM: Nitrous oxide-stimulated promoter YP_004414542.1 COGs: COG4245 Uncharacterized protein encoded in toxicity protection region of plasmid R478 contains von Willebrand factor (vWF) domain; InterPro IPR002035; KEGG: hso:HS_0628 hypothetical protein; PFAM: von Willebrand factor, type A; SMART: von Willebrand factor, type A; SPTR: Tellurium resistance protein; IMG reference gene:2504587651; PFAM: von Willebrand factor type A domain YP_004414543.1 KEGG: alv:Alvin_1030 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587652 YP_004414544.1 InterPro IPR017442; KEGG: cpi:Cpin_1174 hypothetical protein; PFAM: Serine/threonine-protein kinase-like domain; SPTR: Putative kinase protein; IMG reference gene:2504587653; PFAM: Protein kinase domain YP_004414545.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012837:IPR007197; KEGG: elm:ELI_3634 anaerobic ribonucleoside-triphosphate reductase activating protein; PFAM: Radical SAM; SPTR: Anaerobic ribonucleoside-triphosphate reductase-activating protein; TIGRFAM: Ribonucleoside-triphosphate reductase activating, anaerobic; IMG reference gene:2504587654; PFAM: Radical SAM superfamily; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase activating protein YP_004414546.1 COGs: COG1328 Oxygen-sensitive ribonucleoside-triphosphate reductase; InterPro IPR005144:IPR012833; KEGG: elm:ELI_3633 anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone; PRIAM: Ribonucleoside-triphosphate reductase; SPTR: Anaerobic ribonucleoside-triphosphate reductase; TIGRFAM: Ribonucleoside-triphosphate reductase, anaerobic; IMG reference gene:2504587655; PFAM: ATP cone domain; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase YP_004414547.1 COGs: COG3264 Small-conductance mechanosensitive channel; InterPro IPR006685; KEGG: gsu:GSU2357 hypothetical protein; PFAM: Mechanosensitive ion channel MscS; SPTR: MscS Mechanosensitive ion channel; IMG reference gene:2504587656; PFAM: Mechanosensitive ion channel YP_004414548.1 COGs: COG1937 conserved hypothetical protein; InterPro IPR003735; KEGG: vpr:Vpar_1572 protein of unknown function DUF156; PFAM: Protein of unknown function DUF156; SPTR: Hypothetical cytosolic protein; IMG reference gene:2504587657; PFAM: Uncharacterised BCR, COG1937 YP_004414549.1 COGs: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenase; InterPro IPR006140:IPR006139; KEGG: afn:Acfer_1520 D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding protein; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain; PRIAM: Glyoxylate reductase (NADP(+)); SPTR: Dehydrogenase; IMG reference gene:2504587658; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain YP_004414550.1 COGs: COG2217 Cation transport ATPase; InterProIPR006404:IPR006416:IPR001757:IPR008250:IPR 005834; KEGG: ere:EUBREC_2968 cation-transporting ATPase, P-type; PFAM: ATPase, P-type, ATPase-associated domain; Haloacid dehalogenase-like hydrolase; PRIAM: Cadmium-exporting ATPase; SPTR: Cadmium-exporting ATPase; TIGRFAM: ATPase, P-type, heavy metal translocating; ATPase, P-type, heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; IMG reference gene:2504587659; PFAM: E1-E2 ATPase; haloacid dehalogenase-like hydrolase; TIGRFAM: heavy metal translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase YP_004414551.1 InterPro IPR006121; KEGG: eel:EUBELI_01434 hypothetical protein; PFAM: Heavy metal transport/detoxification protein; SPTR: Cadmium-exporting ATPase; IMG reference gene:2504587660; PFAM: Heavy-metal-associated domain YP_004414552.1 COGs: COG3182 Uncharacterized iron-regulated membrane protein; InterPro IPR005625; KEGG: axy:AXYL_02326 PepSY-associated TM helix family protein 3; PFAM: PepSY-associated TM helix; SPTR: PepSY-associated TM helix family protein; IMG reference gene:2504587661; PFAM: PepSY-associated TM helix YP_004414553.1 COGs: COG1629 Outer membrane receptor protein mostly Fe transport; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_0719 TonB-dependent receptor plug; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative receptor; IMG reference gene:2504587662; PFAM: TonB-dependent Receptor Plug Domain; TonB dependent receptor YP_004414554.1 COGs: COG2461 conserved hypothetical protein; InterPro IPR015077:IPR007380:IPR012312; KEGG: vpr:Vpar_1721 hypothetical protein; PFAM: Domain of unknown function DUF438; Domain of unknown function DUF1858; Haemerythrin/HHE cation-binding motif; SPTR: Sensory box protein; IMG reference gene:2504587663; PFAM: Family of unknown function (DUF438); Domain of unknown function (DUF1858) YP_004414555.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587664 YP_004414556.1 COGs: COG1301 Na+/H+-dicarboxylate symporter; InterPro IPR001991; KEGG: toc:Toce_0627 sodium:dicarboxylate symporter; PFAM: Sodium:dicarboxylate symporter; SPTR: Proton/sodium-glutamate symport protein GltT; IMG reference gene:2504587665; PFAM: Sodium:dicarboxylate symporter family YP_004414557.1 COGs: COG1285 membrane protein; InterPro IPR003416; KEGG: chy:CHY_1773 MgtC family protein; PFAM: MgtC/SapB transporter; SPTR: Magnesium transporter, MgtC family; IMG reference gene:2504587666; PFAM: MgtC family YP_004414558.1 COGs: COG2855 membrane protein; InterPro IPR018383; KEGG: clj:CLJU_c37810 hypothetical protein; PFAM: Uncharacterised protein family UPF0324, prokaryote; SPTR: Membrane protein; IMG reference gene:2504587667; PFAM: Conserved hypothetical protein 698; TIGRFAM: conserved hypothetical integral membrane protein YP_004414559.1 COGs: COG2262 GTPase; InterPro IPR016496:IPR002917; KEGG: afn:Acfer_1014 GTP-binding proten HflX; PFAM: GTP-binding protein, HSR1-related; SPTR: GTP-binding protein; TIGRFAM: GTP-binding protein, HflX; IMG reference gene:2504587668; PFAM: GTPase of unknown function; TIGRFAM: GTP-binding protein HflX YP_004414560.1 KEGG: phe:Phep_0146 glycosyl transferase family 11; SPTR: Putative alpha-1,2-fucosyltransferase; IMG reference gene:2504587669; PFAM: Glycosyl transferase family 11 YP_004414561.1 InterPro IPR007358; KEGG: vpr:Vpar_0653 hypothetical protein; PFAM: Nucleoid-associated protein NdpA; SPTR: Putative uncharacterized protein; IMG reference gene:2504587670; PFAM: 37-kD nucleoid-associated bacterial protein YP_004414562.1 KEGG: bfo:BRAFLDRAFT_92858 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587671 YP_004414563.1 COGs: COG0673 dehydrogenase and related protein; InterPro IPR000683:IPR004104; KEGG: sss:SSUSC84_0203 putative oxidoreductase; PFAM: Oxidoreductase, N-terminal; Oxidoreductase, C-terminal; PRIAM: Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; SPTR: Oxidoreductase, Gfo/Idh/MocA family; IMG reference gene:2504587673; PFAM: Oxidoreductase family, NAD-binding Rossmann fold; Oxidoreductase family, C-terminal alpha/beta domain YP_004414564.1 COGs: COG5505 integral membrane protein; InterPro IPR008537; KEGG: eel:EUBELI_00204 hypothetical protein; PFAM: Protein of unknown function DUF819; SPTR: Putative membrane protein; IMG reference gene:2504587674; PFAM: Protein of unknown function (DUF819) YP_004414565.1 COGs: COG1879 ABC-type sugar transport system periplasmic component; InterPro IPR001761; KEGG: ret:RHE_CH01210 sugar ABC transporter, substrate-binding protein; PFAM: Periplasmic binding protein/LacI transcriptional regulator; SPTR: Sugar ABC transporter, periplasmic sugar-binding protein; IMG reference gene:2504587676; PFAM: family YP_004414566.1 COGs: COG0840 Methyl-accepting chemotaxis protein; InterPro IPR003660:IPR004089; KEGG: cbe:Cbei_2787 methyl-accepting chemotaxis sensory transducer; PFAM: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SMART: Chemotaxis methyl-accepting receptor, signalling; HAMP linker domain; SPTR: Methyl-accepting chemotaxis protein; IMG reference gene:2504587677; PFAM: HAMP domain; Methyl-accepting chemotaxis protein (MCP) signaling domain YP_004414567.1 COGs: COG0716 Flavodoxins; InterPro IPR010087:IPR008254; KEGG: eel:EUBELI_00571 hypothetical protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin; TIGRFAM: Flavodoxin, short chain; IMG reference gene:2504587678; PFAM: Flavodoxin; TIGRFAM: flavodoxin, short chain YP_004414568.1 KEGG: elm:ELI_2754 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587679 YP_004414569.1 COGs: COG0426 flavoprotein; InterPro IPR010087:IPR008254; KEGG: eel:EUBELI_00571 hypothetical protein; PFAM: Flavodoxin/nitric oxide synthase; SPTR: Flavodoxin; TIGRFAM: Flavodoxin, short chain; IMG reference gene:2504587680; PFAM: Flavodoxin; TIGRFAM: flavodoxin, short chain YP_004414570.1 COGs: COG2342 extracellular endo alpha-1 4 polygalactosaminidase or related polysaccharide hydrolase; InterPro IPR004352; KEGG: fbc:FB2170_04690 hypothetical protein; PFAM: TM1410 hypothetical-related protein; SPTR: Cysteine--tRNA ligase; IMG reference gene:2504587681; PFAM: TM1410 hypothetical-related protein; TIGRFAM: possible cysteinyl-tRNA synthetase, Methanococcus type YP_004414571.1 KEGG: cre:CHLREDRAFT_6783 SNF2 superfamily protein; SPTR: Dyp-type peroxidase family protein; IMG reference gene:2504587682 YP_004414572.1 COGs: COG4267 membrane protein; KEGG: cac:CA_C0735 hypothetical protein; SPTR: Putative Transmembrane protein; IMG reference gene:2504587683 YP_004414573.1 COGs: COG0438 Glycosyltransferase; InterPro IPR001296:IPR022622; KEGG: bbe:BBR47_05590 hypothetical protein; PFAM: Domain of unknown function DUF3492; Glycosyl transferase, group 1; SPTR: Glycosyl transferase, group 1 family; IMG reference gene:2504587684; PFAM: Glycosyl transferases group 1; Domain of unknown function (DUF3492) YP_004414574.1 COGs: COG4878 conserved hypothetical protein; InterPro IPR018695; KEGG: bbe:BBR47_05580 hypothetical protein; PFAM: Protein of unknown function DUF2194; SPTR: Putative uncharacterized protein; IMG reference gene:2504587685; PFAM: Uncharacterized protein conserved in bacteria (DUF2194) YP_004414575.1 KEGG: bbe:BBR47_05570 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587686 YP_004414576.1 COGs: COG0451 Nucleoside-diphosphate-sugar epimerase; InterPro IPR001509:IPR003018; KEGG: bbe:BBR47_05560 hypothetical protein; PFAM: NAD-dependent epimerase/dehydratase; SMART: GAF; SPTR: Putative GAF domain protein; IMG reference gene:2504587687; PFAM: NAD dependent epimerase/dehydratase family YP_004414577.1 COGs: COG0791 Cell wall-associated hydrolase (invasion-associated protein); InterPro IPR002477:IPR000064; KEGG: vpr:Vpar_1182 NLP/P60 protein; PFAM: NLP/P60; Peptidoglycan binding-like; SPTR: LysM domain/NLP/P60 family protein; IMG reference gene:2504587688; PFAM: NlpC/P60 family; Putative peptidoglycan binding domain YP_004414578.1 COGs: COG1316 Transcriptional regulator; InterPro IPR004474; KEGG: afn:Acfer_0288 cell envelope-related transcriptional attenuator; PFAM: Cell envelope-related transcriptional attenuator; SPTR: Regulation of penicillin binding protein 5 production; TIGRFAM: Cell envelope-related transcriptional attenuator; IMG reference gene:2504587689; PFAM: Cell envelope-related transcriptional attenuator domain; TIGRFAM: cell envelope-related function transcriptional attenuator common domain YP_004414579.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587690 YP_004414580.1 COGs: COG2038 NaMN:DMB phosphoribosyltransferase; InterPro IPR017846:IPR003200; KEGG: vpr:Vpar_1457 nicotinate-nucleotide/dimethylbenzimidazolephosp horibosyltransferase; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like; PRIAM: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; SPTR: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; TIGRFAM:Nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase, prokaryotic; IMG reference gene:2504587691; PFAM: Phosphoribosyltransferase; TIGRFAM: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase YP_004414581.1 COGs: COG2183 Transcriptional accessory protein; InterPro IPR018974:IPR003029:IPR022967:IPR006641; KEGG: afn:Acfer_2044 Tex-like protein; PFAM: Tex-like protein, N-terminal; Ribosomal protein S1, RNA-binding domain; SMART: Resolvase, RNase H-like fold; RNA-binding domain, S1; SPTR: Protein YhgF; IMG reference gene:2504587692; PFAM: Tex-like protein N-terminal domain; S1 RNA binding domain YP_004414582.1 COGs: COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system; InterPro IPR012753:IPR007712; KEGG: spp:SPP_0032 plasmid addiction system poison protein; PFAM: Plasmid stabilisation system; SPTR: Toxin-antitoxin system, toxin component, RelE family; TIGRFAM: Addiction module toxin, RelE/StbE; IMG reference gene:2504587693; PFAM: Plasmid stabilisation system protein; TIGRFAM: addiction module toxin, RelE/StbE family YP_004414583.1 KEGG: fma:FMG_0052 hypothetical protein; SPTR: Conserved domain protein; IMG reference gene:2504587694 YP_004414584.1 SPTR: Toxin-antitoxin system protein; IMG reference gene:2504587695 YP_004414585.1 InterPro IPR001450; KEGG: sth:STH228 putative polyferredoxin; PFAM: 4Fe-4S binding domain; SPTR: Putative polyferredoxin; IMG reference gene:2504587696 YP_004414586.1 COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: aar:Acear_2169 glycosyl transferase family 9; PFAM: Glycosyl transferase, family 9; SPTR: Putative lipopolysaccharide heptosyltransferase II; IMG reference gene:2504587697; PFAM: Glycosyltransferase family 9 (heptosyltransferase); TIGRFAM: lipopolysaccharide heptosyltransferase II YP_004414587.1 COGs: COG0553 Superfamily II DNA/RNA helicase SNF2 family; InterProIPR014001:IPR001650:IPR007527:IPR013663:IPR 000330; KEGG: cth:Cthe_2451 SNF2-related protein; PFAM: SNF2-related; Helicase, SWF/SNF/SWI type, bacterial; Zinc finger, SWIM-type; Helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; Helicase, C-terminal; SPTR: Helicase, Snf2 family; IMG reference gene:2504587698; PFAM: Helicase conserved C-terminal domain; SNF2 family N-terminal domain; Bacterial SNF2 helicase associated; SWIM zinc finger YP_004414588.1 COGs: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; InterPro IPR001126; KEGG: afn:Acfer_0062 DNA-directed DNA polymerase; PFAM: DNA-repair protein, UmuC-like; PRIAM: DNA-directed DNA polymerase; SPTR: DNA polymerase IV; IMG reference gene:2504587699; PFAM: impB/mucB/samB family C-terminal; IMS family HHH motif; impB/mucB/samB family YP_004414589.1 COGs: COG3731 Phosphotransferase system sorbitol-specific component IIA; InterPro IPR004716; KEGG: cdl:CDR20291_2305 PTS system, IIa component; PFAM: Phosphotransferase system, glucitol/sorbitol-specific IIA component; SPTR: Putative PTS system, glucitol/sorbitol-specific, IIA component; IMG reference gene:2504587701; PFAM: PTS system glucitol/sorbitol-specific IIA component YP_004414590.1 COGs: COG1048 Aconitase A; InterPro IPR006250:IPR001030:IPR000573; KEGG: tjr:TherJR_2355 aconitate hydratase; PFAM: Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha; Aconitase A/isopropylmalate dehydratase small subunit, swivel; SPTR: Putative aconitate hydratase; TIGRFAM: Aconitase, putative; IMG reference gene:2504587702; PFAM: Aconitase C-terminal domain; Aconitase family (aconitate hydratase); TIGRFAM: aconitate hydratase, putative, Aquifex type YP_004414591.1 COGs: COG0372 Citrate synthase; InterPro IPR002020; KEGG: csh:Closa_2133 citrate synthase; PFAM: Citrate synthase-like; SPTR: 2-methylcitrate synthase; IMG reference gene:2504587703; PFAM: Citrate synthase YP_004414592.1 COGs: COG0473 Isocitrate/isopropylmalate dehydrogenase; InterPro IPR001804; KEGG: amt:Amet_1319 isocitrate dehydrogenase (NAD(+)); PFAM: Isocitrate/isopropylmalate dehydrogenase; PRIAM: Isocitrate dehydrogenase (NAD(+)); SPTR: Isocitrate dehydrogenase; IMG reference gene:2504587704; PFAM: Isocitrate/isopropylmalate dehydrogenase; TIGRFAM: isocitrate dehydrogenase, NAD-dependent, mitochondrial type; isopropylmalate/isohomocitrate dehydrogenases YP_004414593.1 COGs: COG0469 Pyruvate kinase; InterPro IPR015795:IPR001697:IPR015793; KEGG: vpr:Vpar_1405 pyruvate kinase; PFAM: Pyruvate kinase, barrel; Pyruvate kinase, C-terminal-like; PRIAM: Pyruvate kinase; SPTR: Pyruvate kinase; TIGRFAM: Pyruvate kinase; IMG reference gene:2504587705; PFAM: Pyruvate kinase, barrel domain; Pyruvate kinase, alpha/beta domain; TIGRFAM: pyruvate kinase YP_004414594.1 COGs: COG0254 Ribosomal protein L31; InterPro IPR002150; KEGG: afn:Acfer_0419 ribosomal protein L31; PFAM: Ribosomal protein L31; SPTR: 50S ribosomal protein L31; TIGRFAM: Ribosomal protein L31; IMG reference gene:2504587706; PFAM: Ribosomal protein L31; TIGRFAM: ribosomal protein L31 YP_004414595.1 COGs: COG3872 metal-dependent protein; InterPro IPR010787; KEGG: afn:Acfer_0420 protein of unknown function DUF1385; PFAM: Protein of unknown function DUF1385; SPTR: Putative membrane protein; IMG reference gene:2504587707; PFAM: Protein of unknown function (DUF1385) YP_004414596.1 COGs: COG0216 Protein chain release factor A; HAMAP: Peptide chain release factor 1; InterPro IPR004373:IPR005139:IPR000352; KEGG: tjr:TherJR_2905 peptide chain release factor 1; PFAM: Peptide chain release factor class I/class II; Peptide chain release factor; SMART: Peptide chain release factor; SPTR: Peptide chain release factor 1; TIGRFAM: Peptide chain release factor 1; IMG reference gene:2504587708; PFAM: PCRF domain; RF-1 domain; TIGRFAM: peptide chain release factor 1 YP_004414597.1 COGs: COG2890 Methylase of polypeptide chain release factors; InterPro IPR019874:IPR004556:IPR007848; KEGG: gsu:GSU3103 HemK family modification methylase; PFAM: Methyltransferase small; SPTR: Protein-(Glutamine-N5) methyltransferase; TIGRFAM: Protein-(glutamine-N5) methyltransferase, release factor-specific; Modification methylase HemK; IMG reference gene:2504587709; PFAM: Methyltransferase small domain; TIGRFAM: HemK family putative methylases; protein-(glutamine-N5) methyltransferase, release factor-specific YP_004414598.1 COGs: COG0009 Putative translation factor (SUA5); InterPro IPR004388:IPR006070:IPR005145; KEGG: afn:Acfer_0423 SUA5/YciO/YrdC/YwlC family protein; PFAM: Sua5/YciO/YrdC, N-terminal; SUA5; SPTR: SUA5 protein; TIGRFAM: Sua5/YciO/YrdC/YwlC; IMG reference gene:2504587710; PFAM: yrdC domain; SUA5 domain; TIGRFAM: Sua5/YciO/YrdC/YwlC family protein YP_004414599.1 KEGG: ere:EUBREC_3089 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587711 YP_004414600.1 InterPro IPR018841; KEGG: cow:Calow_1395 hypothetical protein; PFAM: Protein of unknown function DUF2442; SPTR: Putative uncharacterized protein; IMG reference gene:2504587712; PFAM: Protein of unknown function (DUF2442) YP_004414601.1 COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: cbf:CLI_0721 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Transcriptional regulator, MarR family; IMG reference gene:2504587713; PFAM: MarR family YP_004414602.1 COGs: COG0561 hydrolase of the HAD superfamily; InterPro IPR013200; KEGG: cce:Ccel_1851 Cof-like hydrolase; PFAM: HAD superfamily hydrolase-like, type 3; SPTR: HAD-superfamily hydrolase, subfamily IIB; IMG reference gene:2504587714; PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: HAD-superfamily hydrolase, subfamily IIB YP_004414603.1 COGs: COG0295 Cytidine deaminase; InterPro IPR002125:IPR006262; KEGG: vpr:Vpar_0409 cytidine deaminase; PFAM: CMP/dCMP deaminase, zinc-binding; SPTR: Cytidine deaminase; TIGRFAM: Cytidine deaminase, homotetrameric; IMG reference gene:2504587715; PFAM: Cytidine and deoxycytidylate deaminase zinc-binding region; TIGRFAM: cytidine deaminase, homotetrameric YP_004414604.1 COGs: COG0213 Thymidine phosphorylase; InterPro IPR018090:IPR013102:IPR000312:IPR017459; KEGG: clo:HMPREF0868_0655 pyrimidine-nucleoside phosphorylase; PFAM: Glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal; Glycosyl transferase, family 3, N-terminal; PRIAM: Pyrimidine-nucleoside phosphorylase; SMART: Pyrimidine nucleoside phosphorylase, C-terminal; SPTR: Pyrimidine-nucleoside phosphorylase; TIGRFAM: Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic; IMG reference gene:2504587716; PFAM: Glycosyl transferase family, a/b domain; Pyrimidine nucleoside phosphorylase C-terminal domain; Glycosyl transferase family, helical bundle domain; TIGRFAM: pyrimidine-nucleoside phosphorylase YP_004414605.1 COGs: COG0785 Cytochrome c biogenesis protein; InterPro IPR003834; KEGG: afn:Acfer_1010 cytochrome c biogenesis protein transmembrane region; PFAM: Cytochrome c assembly protein, transmembrane domain; SPTR: Cytochrome c biogenesis protein CcdA; IMG reference gene:2504587717; PFAM: Cytochrome C biogenesis protein transmembrane region YP_004414606.1 COGs: COG0526 Thiol-disulfide isomerase and thioredoxins; InterPro IPR000866; KEGG: afn:Acfer_1009 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen; PFAM: Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant; SPTR: Thioredoxin family protein; IMG reference gene:2504587718; PFAM: AhpC/TSA family YP_004414607.1 COGs: COG2768 Uncharacterized Fe-S center protein; InterPro IPR007160; KEGG: afn:Acfer_1790 4Fe-4S ferredoxin iron-sulfur binding domain protein; PFAM: Domain of unknown function DUF362; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504587719; PFAM: Domain of unknown function (DUF362) YP_004414608.1 COGs: COG0569 K+ transport systems NAD-binding component; InterPro IPR003148:IPR006037; KEGG: dhd:Dhaf_2907 potassium transporter peripheral membrane component; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; SPTR: Trk system potassium uptake protein TrkA 1; IMG reference gene:2504587720; PFAM: TrkA-N domain; TrkA-C domain YP_004414609.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: rxy:Rxyl_1271 cation transporter; PFAM: Cation transporter; SPTR: Putative Trk system potassium uptake protein; IMG reference gene:2504587721; PFAM: Cation transport protein YP_004414610.1 COGs: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; InterPro IPR004839; KEGG: elm:ELI_3637 aminotransferase class I and II; PFAM: Aminotransferase, class I/classII; PRIAM: Cystathionine beta-lyase; SPTR: Hemolysin; IMG reference gene:2504587722; PFAM: Aminotransferase class I and II YP_004414611.1 COGs: COG1373 ATPase (AAA+ superfamily); KEGG: tit:Thit_0639 AAA family ATPase; SPTR: Putative uncharacterized protein; IMG reference gene:2504587723 YP_004414612.1 COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: amt:Amet_3707 cystathionine gamma-synthase; PFAM: Cys/Met metabolism, pyridoxal phosphate-dependent enzyme; SPTR: Cystathionine beta-lyase; IMG reference gene:2504587724; PFAM: Cys/Met metabolism PLP-dependent enzyme YP_004414613.1 COGs: COG0787 Alanine racemase; HAMAP: Alanine racemase; InterPro IPR000821:IPR001608:IPR011079; KEGG: dds:Ddes_0171 alanine racemase; PFAM: Alanine racemase, N-terminal; Alanine racemase, C-terminal; PRIAM: Alanine racemase; SPTR: Alanine racemase; TIGRFAM: Alanine racemase; IMG reference gene:2504587725; PFAM: Alanine racemase, C-terminal domain; Alanine racemase, N-terminal domain; TIGRFAM: alanine racemase YP_004414614.1 COGs: COG0172 Seryl-tRNA synthetase; HAMAP: Seryl-tRNA synthetase, class IIa; InterPro IPR002317:IPR015866:IPR002314; KEGG: tjr:TherJR_0014 seryl-tRNA synthetase; PFAM: Aminoacyl-tRNA synthetase, class II (G/ H/ P/ S), conserved domain; Seryl-tRNA synthetase, class IIa, N-terminal; PRIAM: Serine--tRNA ligase; SPTR: Seryl-tRNA synthetase; TIGRFAM: Seryl-tRNA synthetase, class IIa; IMG reference gene:2504587726; PFAM: Seryl-tRNA synthetase N-terminal domain; tRNA synthetase class II core domain (G, H, P, S and T); TIGRFAM: seryl-tRNA synthetase YP_004414615.1 KEGG: rci:RRC32 hypothetical protein; SPTR: ATP-dependent DNA helicase RecG; IMG reference gene:2504587727 YP_004414616.1 COGs: COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain; InterPro IPR001789:IPR000792; KEGG: dma:DMR_15450 NarL family two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SMART: Signal transduction response regulator, receiver domain; Transcription regulator LuxR, C-terminal; SPTR: DNA-binding response regulator UhpA; IMG reference gene:2504587728; PFAM: Response regulator receiver domain; Bacterial regulatory proteins, luxR family YP_004414617.1 COGs: COG4585 Signal transduction histidine kinase; InterPro IPR003594:IPR011712; KEGG: dma:DMR_15440 two-component sensor histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; SPTR: Sensor histidine kinase; IMG reference gene:2504587729; PFAM: Histidine kinase; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YP_004414618.1 COGs: COG3221 ABC-type phosphate/phosphonate transport system periplasmic component; InterPro IPR005770; KEGG: dma:DMR_15430 hypothetical protein; SPTR: Putative phosphonate-binding periplasmic protein; TIGRFAM: Phosphonate-binding periplasmic protein; IMG reference gene:2504587730; TIGRFAM: phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein YP_004414619.1 InterPro IPR001401; KEGG: gmc:GY4MC1_1648 dynamin family protein; PFAM: Dynamin, GTPase domain; SPTR: Dynamin family protein; IMG reference gene:2504587731; PFAM: Dynamin family YP_004414620.1 InterPro IPR001173; KEGG: bpb:bpr_I0357 glycosyl transferase GT2 family protein; PFAM: Glycosyl transferase, family 2; SPTR: Putative glycosyl transferase; IMG reference gene:2504587732; PFAM: Glycosyl transferase family 2 YP_004414621.1 InterPro IPR003748; KEGG: dhd:Dhaf_2252 protein of unknown function DUF169; PFAM: Protein of unknown function DUF169; SPTR: Putative uncharacterized protein; IMG reference gene:2504587733; PFAM: Uncharacterised ArCR, COG2043 YP_004414622.1 COGs: COG0168 Trk-type K+ transport systems membrane components; InterPro IPR003445; KEGG: dhd:Dhaf_2905 cation transporter; PFAM: Cation transporter; SPTR: Potassium uptake protein TrkH; IMG reference gene:2504587734; PFAM: Cation transport protein YP_004414623.1 COGs: COG0005 Purine nucleoside phosphorylase; InterPro IPR000845; KEGG: slp:Slip_1164 purine or other phosphorylase family 1; PFAM: Nucleoside phosphorylase domain; SPTR: Phosphorylase, family 2; IMG reference gene:2504587735; PFAM: Phosphorylase superfamily YP_004414624.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050:IPR007197:IPR022431:IPR006638; KEGG: slp:Slip_1165 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: Menaquinone biosynthesis protein, SCO4550 family; TIGRFAM: FO synthase, subunit 2; Menaquinone biosynthesis, SCO4550; IMG reference gene:2504587736; PFAM: Radical SAM superfamily; TIGRFAM: radical SAM domain protein, CofH subfamily; menaquinone biosynthesis protein, SCO4550 family YP_004414625.1 COGs: COG1060 Thiamine biosynthesis protein ThiH; InterPro IPR020050:IPR007197:IPR006638; KEGG: slp:Slip_1167 radical SAM domain protein; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB; SPTR: FO synthase; TIGRFAM: FO synthase, subunit 2; IMG reference gene:2504587737; PFAM: Radical SAM superfamily; TIGRFAM: putative menaquinone biosynthesis protein, SCO4494 family; radical SAM domain protein, CofH subfamily YP_004414626.1 KEGG: csh:Closa_3690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587738 YP_004414627.1 KEGG: csh:Closa_3691 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587739 YP_004414628.1 KEGG: csh:Closa_3692 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587740 YP_004414629.1 COGs: COG0607 Rhodanese-related sulfurtransferase; InterPro IPR001763; KEGG: bpb:bpr_I2677 rhodanese domain-containing protein; PFAM: Rhodanese-like; SMART: Rhodanese-like; SPTR: Rhodanese domain protein; IMG reference gene:2504587741; PFAM: Rhodanese-like domain YP_004414630.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587742 YP_004414631.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587743 YP_004414632.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587744 YP_004414633.1 COGs: COG2367 Beta-lactamase class A; KEGG: afn:Acfer_0879 beta-lactamase class A-like protein; SPTR: Beta-lactamase; IMG reference gene:2504587745 YP_004414634.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587746 YP_004414635.1 KEGG: vei:Veis_1817 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587747 YP_004414636.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587748 YP_004414637.1 COGs: COG1263 Phosphotransferase system IIC components glucose/maltose/N-acetylglucosamine-specific; InterPro IPR001127:IPR003352:IPR018113:IPR011535; KEGG: ere:EUBREC_1425 PTS system, glucose subfamily, IIA subunit; PFAM: Phosphotransferase system, EIIC; Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system EIIB/cysteine, phosphorylation site; SPTR: PTS system glucose-specific EIICBA component; TIGRFAM: Phosphotransferase system, sugar-specific permease EIIA 1 domain; Phosphotransferase system, glucose-like IIB component; IMG reference gene:2504587749; PFAM: Phosphotransferase system, EIIC; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1; phosphotransferase system, EIIB; TIGRFAM: PTS system, glucose-like IIB component; PTS system, glucose subfamily, IIA component YP_004414638.1 COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216; KEGG: apv:Apar_0744 methyltransferase type 11; PFAM: Methyltransferase type 11; SPTR: Putative methyltransferase; IMG reference gene:2504587750; PFAM: Methyltransferase domain YP_004414639.1 COGs: COG1592 Rubrerythrin; InterPro IPR003251; KEGG: cce:Ccel_1869 rubrerythrin; PFAM: Rubrerythrin; SPTR: Rubrerythrin; IMG reference gene:2504587751; PFAM: Rubrerythrin YP_004414640.1 COGs: COG0071 Molecular chaperone (small heat shock protein); InterPro IPR002068; KEGG: cac:CA_C3714 molecular chaperone (small heat shock protein), HSP18; PFAM: Heat shock protein Hsp20; SPTR: Heat shock protein, Hsp20 family; IMG reference gene:2504587752; PFAM: Hsp20/alpha crystallin family YP_004414641.1 InterPro IPR004360; KEGG: etr:ETAE_1244 glyoxalase/bleomycin resistance; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; SPTR: Glyoxalase family protein; IMG reference gene:2504587753; PFAM: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily YP_004414642.1 COGs: COG1882 Pyruvate-formate lyase; InterPro IPR004184:IPR005949:IPR001150; KEGG: eel:EUBELI_20055 formate C-acetyltransferase; PFAM: Pyruvate formate-lyase, PFL; Formate C-acetyltransferase glycine radical; PRIAM: Formate C-acetyltransferase; SPTR: Formate acetyltransferase; TIGRFAM: Formate acetyltransferase; IMG reference gene:2504587754; PFAM: Glycine radical; Pyruvate formate lyase; TIGRFAM: formate acetyltransferase 1 YP_004414643.1 COGs: COG1180 Pyruvate-formate lyase-activating enzyme; InterPro IPR012838:IPR007197; KEGG: fsu:Fisuc_1047 pyruvate formate-lyase activating enzyme; PFAM: Radical SAM; PRIAM: [Formate-C-acetyltransferase]-activating enzyme; SPTR: Pyruvate formate-lyase 1-activating enzyme; TIGRFAM: Pyruvate formate-lyase activating; IMG reference gene:2504587755; PFAM: Radical SAM superfamily; TIGRFAM: pyruvate formate-lyase 1-activating enzyme YP_004414644.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587756 YP_004414645.1 KEGG: hor:Hore_15690 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587757 YP_004414646.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587758 YP_004414647.1 KEGG: ccv:CCV52592_1750 von Willebrand factor type A domain-containing protein; SPTR: Putative von Willebrand factor type A domain protein; IMG reference gene:2504587759; PFAM: von Willebrand factor type A domain YP_004414648.1 COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dhd:Dhaf_4517 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; SPTR: Iron-sulfur cluster-binding protein; IMG reference gene:2504587761; PFAM: Cysteine-rich domain YP_004414649.1 COGs: COG0277 FAD/FMN-containing dehydrogenase; InterPro IPR006094:IPR004113; KEGG: mta:Moth_2308 FAD linked oxidase-like; PFAM: FAD-linked oxidase, C-terminal; FAD linked oxidase, N-terminal; PRIAM: D-lactate dehydrogenase (cytochrome); SPTR: Glycolate oxidase, subunit GlcD; IMG reference gene:2504587762; PFAM: FAD binding domain; FAD linked oxidases, C-terminal domain; TIGRFAM: glycolate oxidase, subunit GlcD YP_004414650.1 COGs: COG0471 Di- and tricarboxylate transporter; InterPro IPR001898; KEGG: shi:Shel_26980 anion transporter; PFAM: Sodium/sulphate symporter; SPTR: Anion transporter; TIGRFAM: Sodium/sulphate symporter; IMG reference gene:2504587763; PFAM: Sodium:sulfate symporter transmembrane region; TIGRFAM: anion transporter YP_004414651.1 COGs: COG2954 conserved hypothetical protein; InterPro IPR008172; KEGG: hha:Hhal_1263 adenylate cyclase; PFAM: Adenylate cyclase; SPTR: Adenylate cyclase; IMG reference gene:2504587764; PFAM: CYTH domain YP_004414652.1 COGs: COG0015 Adenylosuccinate lyase; InterPro IPR022761:IPR004769:IPR019468; KEGG: bhy:BHWA1_00426 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2504587766; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase YP_004414653.1 COGs: COG0104 Adenylosuccinate synthase; InterPro IPR001114; KEGG: afn:Acfer_0046 adenylosuccinate synthetase; PFAM: Adenylosuccinate synthetase; PRIAM: Adenylosuccinate synthase; SMART: Adenylosuccinate synthetase; SPTR: Adenylosuccinate synthetase; TIGRFAM: Adenylosuccinate synthetase; IMG reference gene:2504587767; PFAM: Adenylosuccinate synthetase; TIGRFAM: adenylosuccinate synthase YP_004414654.1 COGs: COG0609 ABC-type Fe3+-siderophore transport system permease component; InterPro IPR000522; KEGG: vpr:Vpar_1694 transport system permease protein; PFAM: ABC transporter permease protein; SPTR: Ferrichrome transport system permease protein FhuG; IMG reference gene:2504587768; PFAM: FecCD transport family YP_004414655.1 COGs: COG1120 ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components; InterPro IPR003593:IPR003439; KEGG: rxy:Rxyl_0416 ABC transporter-like protein; PFAM: ABC transporter-like; PRIAM: Iron-chelate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Ferrichrome transport ATP-binding protein FhuC; IMG reference gene:2504587769; PFAM: ABC transporter YP_004414656.1 COGs: COG1131 ABC-type multidrug transport system ATPase component; InterPro IPR003593:IPR003439; KEGG: bpt:Bpet0143 ABC transporter ATP-binding protein; PFAM: ABC transporter-like; PRIAM: Sulfate-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Nodulation ATP-binding protein I; IMG reference gene:2504587770; PFAM: ABC transporter YP_004414657.1 InterPro IPR013525; KEGG: dap:Dacet_0817 ABC-2 type transporter; PFAM: ABC-2 type transporter; SPTR: Putative ABC-2 transporter, permease protein; IMG reference gene:2504587771; PFAM: ABC-2 type transporter YP_004414658.1 COGs: COG0614 ABC-type Fe3+-hydroxamate transport system periplasmic component; InterPro IPR002491; KEGG: dap:Dacet_0821 periplasmic binding protein; PFAM: Periplasmic binding protein; SPTR: Putative iron compound ABC transporter, iron compound-binding protein; IMG reference gene:2504587772; PFAM: Periplasmic binding protein YP_004414659.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: afn:Acfer_0385 TonB-dependent receptor; PFAM: TonB-dependent receptor, beta-barrel; TonB-dependent receptor, plug; SPTR: Putative receptor; IMG reference gene:2504587773; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004414660.1 COGs: COG4771 Outer membrane receptor for ferrienterochelin and colicins; InterPro IPR012910:IPR000531; KEGG: vpr:Vpar_1696 TonB-dependent receptor; PFAM: TonB-dependent receptor, plug; TonB-dependent receptor, beta-barrel; SPTR: Putative receptor; IMG reference gene:2504587774; PFAM: TonB dependent receptor; TonB-dependent Receptor Plug Domain YP_004414661.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587775 YP_004414662.1 COGs: COG1979 Uncharacterized oxidoreductase Fe-dependent alcohol dehydrogenase family; InterPro IPR001670; KEGG: bpb:bpr_III156 iron-containing alcohol dehydrogenase; PFAM: Alcohol dehydrogenase, iron-type; PRIAM: Alcohol dehydrogenase (NADP(+)); SPTR: NADH-dependent butanol dehydrogenase A; IMG reference gene:2504587776; PFAM: Iron-containing alcohol dehydrogenase YP_004414663.1 KEGG: sub:SUB0098 lipoprotein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587777; PFAM: Peptidase propeptide and YPEB domain YP_004414664.1 COGs: COG2801 Transposase and inactivated derivatives; InterPro IPR001584; KEGG: ppy:PPE_03165 putative transposase InsK for insertion sequence element IS150; PFAM: Integrase, catalytic core; SPTR: Putative transposase InsK; IMG reference gene:2504587778; PFAM: Integrase core domain YP_004414665.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587779 YP_004414666.1 IMG reference gene:2504587780 YP_004414667.1 COGs: COG1219 ATP-dependent protease Clp ATPase subunit; InterPro IPR004487:IPR003593:IPR013093:IPR019489; KEGG: pmx:PERMA_1325 ATP-dependent protease ATP-binding subunit ClpX; PFAM: ATPase, AAA-2; Clp ATPase, C-terminal; SMART: ATPase, AAA+ type, core; SPTR: ATP-dependent Clp protease, ATP-binding subunit ClpX; TIGRFAM: Clp protease, ATP-binding subunit ClpX; IMG reference gene:2504587781; PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; TIGRFAM: endopeptidase Clp ATP-binding regulatory subunit (clpX) YP_004414668.1 SPTR: Glycosyltransferase; IMG reference gene:2504587782 YP_004414669.1 InterPro IPR012893; KEGG: elm:ELI_1895 hypothetical protein; PFAM: HipA-like, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504587783; PFAM: HipA-like C-terminal domain YP_004414670.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587784 YP_004414671.1 SPTR: Putative uncharacterized protein; IMG reference gene:2504587785 YP_004414672.1 InterPro IPR012893; KEGG: hpm:HPSJM_06985 hypothetical protein; PFAM: HipA-like, C-terminal; SPTR: Putative uncharacterized protein; IMG reference gene:2504587786; PFAM: HipA-like C-terminal domain YP_004414673.1 COGs: COG0620 Methionine synthase II (cobalamin-independent); InterPro IPR002629; KEGG: afn:Acfer_0167 methionine synthase vitamin-B12 independent; PFAM: Methionine synthase, vitamin-B12 independent; SPTR: Vitamin-B12 independent methionine synthase family protein; IMG reference gene:2504587787; PFAM: Cobalamin-independent synthase, Catalytic domain YP_004414674.1 COGs: COG0531 Amino acid transporter; InterPro IPR004841; KEGG: mpd:MCP_2610 amino acid transporter; PFAM: Amino acid permease domain; SPTR: Amino acid permease family protein; IMG reference gene:2504587788; PFAM: Amino acid permease; TIGRFAM: amino acid transporter YP_004414675.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR013702:IPR019494; KEGG: lhk:LHK_01115 GGDEF domain protein; PFAM: Diguanylate cyclase, predicted; FIST C domain; FIST domain, N-terminal; SMART: Diguanylate cyclase, predicted; FIST domain, N-terminal; SPTR: Putative sensory box-containing diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504587789; PFAM: FIST C domain; GGDEF domain; FIST N domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004414676.1 COGs: COG0735 Fe2+/Zn2+ uptake regulation protein; InterPro IPR002481; KEGG: tte:TTE1767 Fe2+/Zn2+ uptake regulation proteins; PFAM: Ferric-uptake regulator; SPTR: Peroxide operon transcriptional regulator; IMG reference gene:2504587790; PFAM: Ferric uptake regulator family YP_004414677.1 KEGG: pat:Patl_3900 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587791; PFAM: Protein of unknown function (DUF3225) YP_004414678.1 COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160:IPR001610; KEGG: elm:ELI_4129 putative GGDEF domain protein; PFAM: Diguanylate cyclase, predicted; SMART: PAC motif; SPTR: Putative diguanylate cyclase domain protein; TIGRFAM: Diguanylate cyclase, predicted; IMG reference gene:2504587792; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain YP_004414679.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: vpr:Vpar_0306 UspA domain protein; PFAM: UspA; SPTR: Universal stress protein; IMG reference gene:2504587793; PFAM: Universal stress protein family YP_004414680.1 COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: adg:Adeg_1585 UspA domain protein; PFAM: UspA; SPTR: Universal stress family protein; IMG reference gene:2504587794; PFAM: Universal stress protein family YP_004414681.1 COGs: COG1171 Threonine dehydratase; InterPro IPR001926:IPR005789; KEGG: clj:CLJU_c15090 threonine dehydratase; PFAM: Pyridoxal phosphate-dependent enzyme, beta subunit; SPTR: Threonine ammonia-lyase; TIGRFAM: Threonine dehydratase II; IMG reference gene:2504587795; PFAM: Pyridoxal-phosphate dependent enzyme; TIGRFAM: threonine ammonia-lyase, biosynthetic, long form; threonine dehydratase, medium form YP_004414682.1 InterPro IPR002781; KEGG: amt:Amet_1578 hypothetical protein; PFAM: Protein of unknown function DUF81; SPTR: Putative uncharacterized protein; IMG reference gene:2504587796; PFAM: Sulfite exporter TauE/SafE YP_004414683.1 COGs: COG2033 Desulfoferrodoxin; InterPro IPR002742; KEGG: csh:Closa_2525 desulfoferrodoxin ferrous iron-binding region; PFAM: Desulfoferrodoxin, ferrous iron-binding domain; SPTR: Superoxide reductase; IMG reference gene:2504587797; PFAM: Desulfoferrodoxin, N-terminal domain; Desulfoferrodoxin; TIGRFAM: desulfoferrodoxin FeS4 iron-binding domain; desulfoferrodoxin; desulfoferrodoxin ferrous iron-binding domain YP_004414684.1 InterPro IPR013096; KEGG: ccu:Ccur_00420 cupin domain-containing protein; PFAM: Cupin 2, conserved barrel; SPTR: Putative mannose-6-phosphate isomerase; IMG reference gene:2504587798; PFAM: Cupin domain YP_004414685.1 COGs: COG0739 Membrane protein related to metalloendopeptidase; InterPro IPR016047; KEGG: vpr:Vpar_1844 peptidase M23; PFAM: Peptidase M23; SPTR: Membrane protein metalloendopeptidase; IMG reference gene:2504587799; PFAM: Peptidase family M23 YP_004414686.1 KEGG: clj:CLJU_c42860 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2504587800 YP_004414687.1 COGs: COG1475 transcriptional regulator protein; InterPro IPR004437:IPR003115; KEGG: bss:BSUW23_20405 site-specific DNA-binding protein; PFAM: ParB-like nuclease; SMART: ParB-like nuclease; SPTR: Stage 0 sporulation protein J; TIGRFAM: ParB-like partition protein; IMG reference gene:2504587801; PFAM: ParB-like nuclease domain; KorB domain; TIGRFAM: ParB-like partition proteins YP_004414688.1 COGs: COG1192 ATPase involved in chromosome partitioning; InterPro IPR002586; KEGG: toc:Toce_2276 chromosome segregation ATPase; PFAM: Cobyrinic acid a,c-diamide synthase; SPTR: Sporulation initiation inhibitor protein Soj; IMG reference gene:2504587802; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain YP_004414689.1 InterPro IPR004223; KEGG: vpr:Vpar_1849 vitamin B12 dependent methionine synthase activation region; PFAM: Vitamin B12-dependent methionine synthase, activation domain; SPTR: Putative 5-methyltetrahydrofolate--homocysteine methyltransferase; IMG reference gene:2504587803; PFAM: Vitamin B12 dependent methionine synthase, activation domain YP_004414690.1 COGs: COG1410 Methionine synthase I cobalamin-binding domain; InterPro IPR006158:IPR003759:IPR003726:IPR000489; KEGG: hmo:HM1_2499 methionine synthase, putative; PFAM: Homocysteine S-methyltransferase; Cobalamin (vitamin B12)-binding; Methionine synthase, cobalamin (vitamin B12)-binding module, cap; Pterin-binding; PRIAM: Methionine synthase; SPTR: Vitamin B12-dependent methionine synthase family protein; IMG reference gene:2504587804; PFAM: Pterin binding enzyme; B12 binding domain; Homocysteine S-methyltransferase; TIGRFAM: methylmalonyl-CoA mutase C-terminal domain; 5-methyltetrahydrofolate--homocysteine methyltransferase YP_004414691.1 COGs: COG0205 6-phosphofructokinase; InterPro IPR012828:IPR000023; KEGG: gmc:GY4MC1_0828 6-phosphofructokinase; PFAM: Phosphofructokinase domain; PRIAM: 6-phosphofructokinase; SPTR: 6-phosphofructokinase 1; TIGRFAM: 6-phosphofructokinase; IMG reference gene:2504587805; PFAM: Phosphofructokinase; TIGRFAM: 6-phosphofructokinase YP_004414692.1 COGs: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); InterPro IPR013982; KEGG: cbe:Cbei_3561 5-aminoimidazole-4-carboxamide ribonucleotide transformylase; PFAM: AICARFT/IMPCHase bienzyme, transformylase domain; PRIAM: Phosphoribosylaminoimidazolecarboxamide formyltransferase; SMART: AICARFT/IMPCHase bienzyme, transformylase domain; SPTR: Purine biosynthesis protein PURH; IMG reference gene:2504587806; PFAM: AICARFT/IMPCHase bienzyme YP_004414693.1 KEGG: tva:TVAG_377870 hypothetical protein; SPTR: Putative phage head-tail adaptor; IMG reference gene:2504587807 YP_004414694.1 COGs: COG0357 S-adenosylmethionine-dependent methyltransferase involved in cell division; InterPro IPR003682; KEGG: afn:Acfer_2075 methyltransferase GidB; PFAM: rRNA small subunit methyltransferase G; SPTR: Ribosomal RNA small subunit methyltransferase G; TIGRFAM: rRNA small subunit methyltransferase G; IMG reference gene:2504587808; PFAM: rRNA small subunit methyltransferase G; TIGRFAM: 16S rRNA (guanine(527)-N(7))-methyltransferase GidB YP_004414695.1 COGs: COG0445 NAD/FAD-utilizing enzyme apparently involved in cell division; HAMAP: Glucose-inhibited division protein A; InterPro IPR004416:IPR002218; KEGG: afn:Acfer_2076 glucose inhibited division protein A; PFAM: Glucose-inhibited division protein A-related; SPTR: tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG; TIGRFAM: Glucose-inhibited division protein A; IMG reference gene:2504587809; PFAM: Glucose inhibited division protein A; TIGRFAM: glucose-inhibited division protein A YP_004414696.1 COGs: COG0486 GTPase; HAMAP: tRNA modification GTPase TrmE; InterPro IPR004520:IPR005225:IPR018948:IPR002917; KEGG: amt:Amet_4797 tRNA modification GTPase TrmE; PFAM: GTP-binding protein TrmE, N-terminal; GTP-binding protein, HSR1-related; SPTR: tRNA modification GTPase mnmE; TIGRFAM: tRNA modification GTPase TrmE; Small GTP-binding protein; IMG reference gene:2504587810; PFAM: GTPase of unknown function; GTP-binding protein TrmE N-terminus; TIGRFAM: small GTP-binding protein domain; tRNA modification GTPase TrmE YP_004414697.1 COGs: COG1847 RNA-binding protein; InterPro IPR001374; KEGG: eel:EUBELI_02066 spoIIIJ-associated protein; PFAM: Single-stranded nucleic acid binding R3H; SMART: Single-stranded nucleic acid binding R3H; SPTR: Jag protein; IMG reference gene:2504587811; PFAM: R3H domain YP_004414698.1 COGs: COG0706 Preprotein translocase subunit YidC; InterPro IPR001708; KEGG: vpr:Vpar_1856 60 kDa inner membrane insertion protein; PFAM: Membrane insertion protein, OxaA/YidC; SPTR: Stage III sporulation protein J; TIGRFAM: Membrane insertion protein, OxaA/YidC; IMG reference gene:2504587812; PFAM: 60Kd inner membrane protein; TIGRFAM: membrane protein insertase, YidC/Oxa1 family, C-terminal domain YP_004414699.1 COGs: COG0759 conserved hypothetical protein; HAMAP: Protein of unknown function DUF37; InterPro IPR002696; KEGG: cyj:Cyan7822_4705 hypothetical protein; PFAM: Protein of unknown function DUF37; SPTR: UPF0161 protein SELSPUOL_01324; TIGRFAM: Protein of unknown function DUF37; IMG reference gene:2504587813; PFAM: Domain of unknown function DUF37; TIGRFAM: conserved hypothetical protein YidD YP_004414700.1 COGs: COG0594 RNase P protein component; InterPro IPR000100; KEGG: ere:EUBREC_3711 ribonuclease P; PFAM: Ribonuclease P; SPTR: Ribonuclease P protein component; TIGRFAM: Ribonuclease P; IMG reference gene:2504587814; PFAM: Ribonuclease P; TIGRFAM: ribonuclease P protein component, eubacterial YP_004414701.1 InterPro IPR000271; KEGG: vpr:Vpar_1859 ribosomal protein L34; PFAM: Ribosomal protein L34; SPTR: 50S ribosomal protein L34; TIGRFAM: Ribosomal protein L34; IMG reference gene:2504587815; PFAM: Ribosomal protein L34; TIGRFAM: ribosomal protein L34, bacterial type