-- dump date 20140620_053951 -- class Genbank::CDS -- table cds_note -- id note YP_001101882.1 identified by similarity to GB:CAA52023.1 YP_001101885.1 identified by match to protein family HMM PF01507 YP_001101886.1 identified by similarity to GB:BAB77476.1 YP_001101887.1 identified by similarity to GB:CAE51711.1 YP_001101892.1 identified by match to protein family HMM PF01343 YP_001101893.1 identified by match to protein family HMM PF01323 YP_001101899.1 identified by similarity to GB:BAC41575.1 YP_001101900.1 identified by match to protein family HMM PF00565 YP_001101901.1 identified by match to protein family HMM PF00216 YP_001101902.1 identified by similarity to GB:AAN87633.1 YP_001101903.1 identified by similarity to GB:AAT09653.1 YP_001101904.1 identified by similarity to GB:CAE12736.1 YP_001101910.1 identified by similarity to GB:AAV97052.1|; match to protein family HMM PF07799 YP_001101912.1 identified by match to protein family HMM PF00665 YP_001101914.1 identified by match to protein family HMM PF00665 YP_001101915.1 identified by similarity to GB:AAZ65818.1 YP_001101916.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_001101917.1 identified by match to protein family HMM PF04986 YP_001101918.1 identified by similarity to GB:AAK64586.1 YP_001101919.1 identified by similarity to GB:CAD57670.1; match to protein family HMM PF07690; match to protein family HMM TIGR00710 YP_001101920.1 identified by match to protein family HMM PF00126 YP_001101921.1 identified by similarity to SP:P02982; match to protein family HMM PF07690; match to protein family HMM TIGR00880 YP_001101922.1 identified by similarity to SP:P03038; match to protein family HMM PF00440; match to protein family HMM PF02909 YP_001101923.1 identified by similarity to GB:AAW58856.1 YP_001101924.1 identified by match to protein family HMM PF04655 YP_001101925.1 identified by match to protein family HMM PF01636 YP_001101926.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_001101928.1 identified by match to protein family HMM PF01656 YP_001101929.1 identified by match to protein family HMM PF02195; match to protein family HMM PF08535; match to protein family HMM TIGR00180 YP_001101930.1 identified by similarity to GB:CAG19260.1 YP_001101932.1 identified by similarity to GB:BAC41599.1 YP_001101936.1 identified by similarity to GB:BAB93678.1 YP_001101937.1 identified by match to protein family HMM PF00145 YP_001101940.1 identified by similarity to GB:AAP44279.1 YP_001101942.1 identified by match to protein family HMM PF01131; match to protein family HMM PF01396; match to protein family HMM PF01751; match to protein family HMM TIGR01056 YP_001101944.1 identified by similarity to GB:AAL59675.1; match to protein family HMM PF07514 YP_001101945.1 identified by similarity to GB:AAL59680.1 YP_001101947.1 identified by similarity to GB:AAL59721.1 YP_001101952.1 identified by similarity to GB:AAL59674.1; match to protein family HMM TIGR02762 YP_001101953.1 identified by similarity to GB:AAL59679.1 YP_001101954.1 identified by similarity to GB:AAM08021.1 YP_001101955.1 identified by similarity to GB:AAL59682.1; match to protein family HMM PF06447 YP_001101956.1 identified by similarity to GB:AAL59672.1; match to protein family HMM TIGR02747 YP_001101957.1 identified by similarity to GB:AAL59683.1 YP_001101958.1 identified by similarity to GB:AAM08034.1 YP_001101960.1 identified by similarity to SP:P69937; match to protein family HMM PF00893 YP_001101961.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001101962.1 identified by similarity to GB:AAX86815.1; match to protein family HMM PF00144 YP_001101963.1 identified by match to protein family HMM PF01609 YP_001101964.1 identified by similarity to GB:AAX86815.1; match to protein family HMM PF00144 YP_001101965.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_001101966.1 identified by similarity to SP:P69937; match to protein family HMM PF00893 YP_001101968.1 identified by similarity to GB:AAM08034.1 YP_001101969.1 identified by match to protein family HMM TIGR02746 YP_001101971.1 identified by similarity to GB:AAL59670.1 YP_001101972.1 identified by similarity to GB:AAL59671.1 YP_001101973.1 identified by match to protein family HMM PF00563 YP_001101974.1 identified by match to protein family HMM PF06834 YP_001101975.1 TraN; TrhN; involved in stabilizing mating pairs during plasmid conjugation; F plasmid TraN appears to recognize OmpA in the recipient cell YP_001101977.1 identified by similarity to GB:AAM08043.1 YP_001101980.1 identified by match to protein family HMM PF07728 YP_001101982.1 identified by match to protein family HMM PF00436; match to protein family HMM TIGR00621 YP_001101983.1 identified by match to protein family HMM PF03837; match to protein family HMM TIGR01913 YP_001101984.1 identified by match to protein family HMM TIGR03033 YP_001101985.1 identified by similarity to GB:AAL59707.1 YP_001101986.1 identified by match to protein family HMM PF00092 YP_001101991.1 identified by match to protein family HMM PF00111 YP_001101996.1 identified by similarity to GB:AAM08083.1 YP_001101999.1 identified by match to protein family HMM PF00145 YP_001102003.1 identified by similarity to GB:CAE51790.1 YP_001102005.1 identified by similarity to SP:P76491 YP_001102006.1 identified by similarity to GB:AAR12555.1 YP_001102009.1 identified by similarity to GB:AAK16082.1 YP_001102011.1 identified by similarity to GB:AAM08013.1; match to protein family HMM PF08273 YP_001102014.1 identified by match to protein family HMM PF02371 YP_001102015.1 identified by match to protein family HMM PF01526 YP_001102016.1 identified by match to protein family HMM PF00589; match to protein family HMM PF02899; match to protein family HMM TIGR02249 YP_001102017.1 streptomycin 3'-adenyltransferase YP_001102018.1 identified by similarity to GB:AAA16194.1; match to protein family HMM PF02522 YP_001102019.1 identified by similarity to SP:P31295; match to protein family HMM PF00166 YP_001102020.1 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth YP_001102021.1 identified by match to protein family HMM PF04986 YP_001102022.1 identified by match to protein family HMM PF00872 YP_001102023.1 identified by similarity to SP:P0AGC9; match to protein family HMM PF00893 YP_001102024.1 identified by match to protein family HMM PF00809; match to protein family HMM TIGR01496 YP_001102025.1 identified by similarity to GB:AAZ95875.1; match to protein family HMM PF00583 YP_001102026.1 identified by similarity to GB:CAE50482.1 YP_001102027.1 identified by match to protein family HMM PF01695 YP_001102028.1 identified by similarity to SP:Q46087; match to protein family HMM PF00665 YP_001102029.1 identified by match to protein family HMM PF00665; match to protein family HMM PF01527 YP_001102030.1 identified by match to protein family HMM PF05621 YP_001102031.1 identified by match to protein family HMM PF00665 YP_001102032.1 identified by match to protein family HMM PF00665 YP_001102033.1 identified by match to protein family HMM PF00563 YP_001102034.1 identified by match to protein family HMM PF05052 YP_001102035.1 identified by match to protein family HMM PF00376; match to protein family HMM TIGR02054 YP_001102036.1 cleaves the carbon-mercury bond of organomercuric compounds YP_001102037.1 identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF01266; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR02053 YP_001102038.1 identified by match to protein family HMM PF00403; match to protein family HMM TIGR02052 YP_001102039.1 identified by match to protein family HMM PF02411 YP_001102040.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02051 YP_001102041.1 identified by match to protein family HMM PF02371 YP_001102044.1 identified by similarity to GB:AAL59702.1 YP_001102045.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_001102049.1 identified by similarity to GB:BAB93677.1 YP_001102051.1 identified by similarity to GB:BAC41610.1 YP_001102052.1 identified by match to protein family HMM PF00589 YP_001102053.1 identified by match to protein family HMM PF00929 YP_001102054.1 identified by similarity to GB:BAB93565.1 YP_001102055.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_001102058.1 identified by similarity to GB:CAG73527.1 YP_001102059.1 identified by match to protein family HMM TIGR02740 YP_001102060.1 identified by match to protein family HMM PF06122 YP_001102061.1 identified by match to protein family HMM PF07916 YP_001102063.1 identified by similarity to GB:AAQ94440.1 YP_001102064.1 identified by match to protein family HMM PF01464 YP_001102069.1 identified by similarity to GB:AAL59744.1 YP_002039226.1 identified by glimmer; putative YP_002039229.1 multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002039230.1 catalyzes the formation of O-phospho-L-homoserine from L-homoserine in threonine biosynthesis from asparate YP_002039231.1 catalyzes the formation of L-threonine from O-phospho-L-homoserine YP_002039232.1 identified by match to protein family HMM PF03883 YP_002039233.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002039234.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002039235.1 forms a trimer; related to eukaryotic protein gephyrin; functions during molybdenum cofactor biosynthesis YP_002039236.1 identified by match to protein family HMM PF01184 YP_002039237.1 identified by match to protein family HMM PF03667 YP_002039239.1 identified by glimmer YP_002039240.1 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria YP_002039241.1 'chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion' YP_002039243.1 identified by match to protein family HMM PF00126 YP_002039245.1 identified by match to protein family HMM PF05838; match to protein family HMM PF09374 YP_002039247.1 identified by match to protein family HMM PF00704; match to protein family HMM PF02839 YP_002039250.1 identified by match to protein family HMM PF00419 YP_002039251.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039252.1 identified by match to protein family HMM PF00577 YP_002039253.1 identified by match to protein family HMM PF00419 YP_002039254.1 identified by match to protein family HMM PF00419 YP_002039255.1 identified by match to protein family HMM PF00419 YP_002039256.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039257.1 identified by match to protein family HMM PF01323 YP_002039260.1 identified by match to protein family HMM PF00126 YP_002039262.1 identified by match to protein family HMM PF05935 YP_002039263.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002039264.1 identified by match to protein family HMM PF07135 YP_002039265.1 identified by match to protein family HMM PF00884 YP_002039266.1 identified by match to protein family HMM PF04055 YP_002039268.1 identified by match to protein family HMM PF05935 YP_002039269.1 exports sodium by using the electrochemical proton gradient to allow protons into the cell; functions in adaptation to high salinity and alkaline pH; activity increases at higher pH; downregulated at acidic pH YP_002039270.1 Na+/H+ antiporter regulatory protein; activates the genes nhaA and osmC YP_002039271.1 identified by match to protein family HMM PF01055 YP_002039272.1 identified by match to protein family HMM TIGR00792 YP_002039273.1 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase YP_002039275.1 catalyzes the formation of FMN from riboflavin and the formation of FAD from FMN; in Bacillus the ribC gene has both flavokinase and FAD synthetase activities YP_002039276.1 'IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 1 subfamily; some organisms carry two different copies of this enzyme' YP_002039277.1 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis YP_002039278.1 identified by match to protein family HMM PF00254 YP_002039279.1 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway YP_002039280.1 identified by glimmer YP_002039282.1 catalyzes the hydrolysis of both purine and pyrimidine ribonucleosides YP_002039283.1 identified by match to protein family HMM PF00072 YP_002039284.1 identified by match to protein family HMM PF02518 YP_002039285.1 identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109 YP_002039286.1 catalyzes the formation of pyruvate from oxaloacetate YP_002039287.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002039288.1 identified by match to protein family HMM PF03390; match to protein family HMM TIGR00783 YP_002039289.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_002039290.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002039291.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_002039292.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_002039293.1 identified by match to protein family HMM PF03802; match to protein family HMM TIGR03124 YP_002039294.1 identified by match to protein family HMM PF01874; match to protein family HMM TIGR03125 YP_002039295.1 'catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis' YP_002039296.1 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers YP_002039297.1 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity YP_002039298.1 involved in the synthesis of a cofactor required for carnitine dehydratase and carnitine racemase activities YP_002039299.1 catalyzes the dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA YP_002039300.1 identified by match to protein family HMM PF00501 YP_002039301.1 'catalyzes formation of L-carnitinyl-CoA by transfering the CoA moiety from gamma-butyrobetainyl-CoA, also catalyzes the formation of crotonobetainyl-CoA by transfer of CoA from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine' YP_002039302.1 catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA YP_002039303.1 catalyzes the exchange of L-carnitine for gamma-butyrobetaine in carnitine metabolism YP_002039306.1 'required for anaerobic carnitine reduction, may act to transfer electrons to crotonobetaine reductase' YP_002039307.1 involved in electron transfer during carnitine metabolism YP_002039308.1 FAD/NAD(P)-binding domain; possibly part of an electron transfer system required for anaerobic carnitine reduction YP_002039310.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002039311.1 identified by match to protein family HMM PF06004 YP_002039313.1 identified by match to protein family HMM PF07338 YP_002039314.1 identified by match to protein family HMM PF00884; match to protein family HMM TIGR01409 YP_002039315.1 'Required for full activity of KefC, a potassium-proton antiporter' YP_002039316.1 transport system that facilitates potassium-efflux YP_002039317.1 catalyzes the reduction of dihydrofolate to tetrahydrofolate YP_002039318.1 'hydrolyzes P(1),P(4)-bis(5'-adenosyl) tetraphosphate to form 2 ADP' YP_002039319.1 protein associated with Co2+ and Mg2+ efflux YP_002039320.1 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin YP_002039321.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002039322.1 'Chaperone involved in the folding of extracytoplasmic proteins, especially OmpA, OmpF and LamB' YP_002039323.1 determines N-hexane tolerance and is involved in outer membrane permeability YP_002039324.1 identified by glimmer YP_002039325.1 functions as a co-chaperone with DnaK; involved in regulation of colanic acid capsule; inner membrane protein; dimerized via transmembrane domain; J-like domain is cytoplasmic and can functionally substitute for DnaJ; stimulates synthesis of colanic acid mucoid capsule through the RcsB/C signal transduction system YP_002039326.1 catalyzes the synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs YP_002039327.1 'transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA' YP_002039328.1 'Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C' YP_002039329.1 identified by match to protein family HMM PF02698 YP_002039330.1 identified by glimmer YP_002039332.2 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002039333.1 catalyzes the formation of L-ribulose from L-arabinose in L-arabinose catabolism YP_002039334.1 catalyzes the phosphorylation of ribulose to ribulose 5-phosphate YP_002039335.1 positive and negative regulator; regulates the araBAD and araFGH operons and other genes involved in the transport and catabolism of L-arabinose YP_002039336.1 identified by match to protein family HMM PF09335 YP_002039337.1 with TbpA and ThiP is part of the thiamine and TPP transport system YP_002039338.1 permease; with TbpA and ThiQ functions in transport of thiamine and thiamine pyrophosphate into the cell; repressed in presence of exogenous thiamine YP_002039339.1 part of the thiamine and TPP transport system tbpA-thiPQ YP_002039341.1 activates sgrS under glucose-phosphate stress conditions YP_002039343.1 catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate in leucine biosynthesis; forms a heterodimer of LeuC/D YP_002039344.1 'dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate' YP_002039345.1 catalyzes the oxidation of 3-isopropylmalate to 3-carboxy-4-methyl-2-oxopentanoate in leucine biosynthesis YP_002039346.1 catalyzes the formation of 2-isopropylmalate from acetyl-CoA and 2-oxoisovalerate in leucine biosynthesis YP_002039347.1 activator for leuABCD operon; member of LysR family of transcriptional activators YP_002039348.1 'catalyzes the formation of 2-acetolactate from pyruvate, leucine sensitive' YP_002039349.1 'with IlvI catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase 3 small subunit' YP_002039350.1 binds D-fructose as an inducer; involved in regulation of operons for central pathways of carbon metabolism YP_002039351.1 MraZ; UPF0040; crystal structure shows similarity to AbrB YP_002039352.1 identified by match to protein family HMM PF01795; match to protein family HMM TIGR00006 YP_002039353.1 membrane bound cell division protein at septum containing leucine zipper motif YP_002039354.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002039355.1 involved in cell wall formation; peptidoglycan synthesis; cytoplasmic enzyme; catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate YP_002039356.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01143 YP_002039357.1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan YP_002039358.1 UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation YP_002039359.1 integral membrane protein involved in stabilizing FstZ ring during cell division YP_002039360.1 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase; involved in cell wall formation; inner membrane-associated; last step of peptidoglycan synthesis YP_002039361.1 Catalyzes the formation of UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate and L-alanine in peptidoglycan synthesis YP_002039362.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002039363.1 involved in septum formation YP_002039364.1 ATP-binding involved in recruitment of FtsK to Z ring; essential cell division protein; colocalizes with FtsZ through direct interaction to the septal ring structure; structurally similar to eukaryotic actin; binds directly to the cell membrane YP_002039365.1 'GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function' YP_002039366.1 zinc-dependent; catalyzes the deacetylation of UDP-(3-O-acyl)-N-acetylglucosamine to UDP-3-O-(3-hydroxytetradecanoyl)-glucosamine in the second step of lipid A biosynthesis YP_002039367.1 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins YP_002039368.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00586 YP_002039370.1 identified by match to protein family HMM PF03884 YP_002039371.1 identified by match to protein family HMM PF07072 YP_002039372.1 catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; involved in coenzyme A biosynthesis YP_002039373.1 catalyzes the NADPH-dependent deamination of GMP to inosine monophosphate YP_002039374.1 identified by match to protein family HMM PF00482 YP_002039375.1 identified by match to protein family HMM PF00437 YP_002039376.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002039377.1 'catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide' YP_002039378.1 identified by match to protein family HMM PF01510 YP_002039379.1 involved in regulation of beta-lactamase; signaling protein YP_002039380.1 identified by match to protein family HMM PF04616 YP_002039381.1 identified by match to protein family HMM TIGR00792 YP_002039382.1 identified by match to protein family HMM PF00324 YP_002039383.1 activates lctPRD operon; autoregulates itself through repression of pdhR-aceEF-lpdA operon; regulates pyruvate dehydrogenase complex YP_002039384.1 E1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC YP_002039385.1 E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains YP_002039386.1 E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide YP_002039387.1 identified by glimmer YP_002039391.1 catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate YP_002039392.1 might be involved in hypersensitivity to nitrofurzone YP_002039394.1 identified by match to protein family HMM PF06062 YP_002039395.1 identified by glimmer YP_002039396.2 transports degraded pectin products into the bacterial cell YP_002039397.1 identified by match to protein family HMM PF07005 YP_002039398.1 catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) YP_002039399.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002039400.1 S-adenosylmethionine provides the aminopropyl moiety required for spermidine biosynthesis from putrescine YP_002039401.1 catalyzes the formation of spermidine from putrescine and S-adenosylmethioninamine YP_002039403.1 laccase; copper-stimulated phenoloxidase and ferroxidase which may be involved in copper detoxification YP_002039404.2 identified by match to protein family HMM PF01011; match to protein family HMM TIGR03074 YP_002039405.1 identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203 YP_002039406.1 catalyzes the interconversion of bicarbonate and carbon dioxide YP_002039407.1 identified by match to protein family HMM PF00005 YP_002039408.1 identified by match to protein family HMM PF01061 YP_002039409.1 identified by match to protein family HMM PF00419 YP_002039410.1 identified by match to protein family HMM PF00577 YP_002039411.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039412.1 identified by match to protein family HMM PF00419 YP_002039413.1 identified by glimmer YP_002039414.1 identified by match to protein family HMM PF03610 YP_002039415.1 identified by match to protein family HMM PF01522 YP_002039416.1 Converts L-aspartate to beta-alanine and provides the major route of beta-alanine production in bacteria. Beta-alanine is essential for the biosynthesis of pantothenate (vitamin B5) YP_002039417.1 catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine YP_002039418.1 'catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate' YP_002039419.1 'catalyzes the formation of 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine and ATP' YP_002039420.2 Polymerase that creates the 3' poly(A) tail found in some mRNA's YP_002039421.1 'this tRNA synthetase lacks the tRNA anticodon interaction domain; instead this enzyme modifies tRNA(Asp) with glutamate by esterifying glutamate to the 2-amino-5-(4,5-dihydroxy-2-cyclopenten-1-yl) moiety of queosine generating a modified nucleoside at the first anticodon position of tRNAAsp; the modified tRNA does not bind elongation factor Tu' YP_002039422.1 identified by match to protein family HMM PF01258; match to protein family HMM TIGR02420 YP_002039423.1 Regulatory factor involved in maltose metabolism YP_002039424.1 identified by match to protein family HMM PF02834; match to protein family HMM TIGR02258 YP_002039425.1 similar in sequence to the ATP-dependent RNA helicase HrpA YP_002039426.1 'bifunctional periplasmic enzyme; contains transglycosylase and transpeptidase activity; major enzyme for peptidoglycan biosynthesis in Escherichia coli; transmembrane protein; forms dimers; three variants, one of which may be a degradation product, while the other appears to result from an alternative initiation site, are found within the cell' YP_002039427.1 identified by glimmer YP_002039428.2 involved with the transport of ferrichrome across the outer membrane; binds the ferrichrome-iron ligand and interacts with the TonB protein YP_002039429.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter YP_002039430.1 Part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter; binds to all hydroxamate siderophores YP_002039431.1 part of the FhuBCD ATP-dependent iron (III) hydroxamate transporter involved in the high-affinity transport of Fe(3+)-ferrichrome YP_002039432.1 identified by glimmer YP_002039433.1 identified by glimmer YP_002039434.1 identified by glimmer YP_002039435.1 identified by match to protein family HMM PF00419 YP_002039436.1 identified by match to protein family HMM PF00577 YP_002039437.1 identified by match to protein family HMM PF00345 YP_002039439.1 identified by match to protein family HMM PF00419 YP_002039440.1 identified by match to protein family HMM PF00419 YP_002039442.1 Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway YP_002039443.1 Acts as an electrical shunt for an outwardly-directed proton pump that is linked to amino acid decarboxylation YP_002039444.1 essential respiratory protein A; may be involved in the transfer of iron-sulfur clusters; essential for growth using oxygen or alternate electron acceptors YP_002039445.1 identified by match to protein family HMM PF03458 YP_002039446.1 solute binding component of the vitamin B12 transport system BtuCDF YP_002039447.1 enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine YP_002039448.1 forms a homotetramer; requires magnesium for activity; catalyzes the hydrolysis of dGTP to form deoxyguanosine and triphosphate YP_002039449.1 protease Do; required at high temperature; degrades damaged proteins YP_002039450.1 'regulates the expression of the operons for the enzymes involved in galactarate, glucarate and glycerate utilization' YP_002039452.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002039453.1 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway YP_002039454.1 catalyzes the uridylylation or deuridylylation of the PII nitrogen regulatory protein YP_002039455.1 'catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn' YP_002039456.1 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit YP_002039457.1 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu YP_002039458.1 Catalyzes the phosphorylation of UMP to UDP YP_002039459.1 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs YP_002039460.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate YP_002039461.1 catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate YP_002039462.1 catalyzes the synthesis of CDP-diglyceride from CTP and phosphatidate YP_002039463.1 catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response YP_002039464.1 'part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins' YP_002039465.1 identified by match to protein family HMM PF03938 YP_002039466.1 adds the O-linked and N-linked 3(R)-hydroxy fatty acids to the glucosamine disaccharide during lipid A biosynthesis YP_002039467.1 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP YP_002039468.1 catalyzes the addition of (R)-3-hydroxytetradecanoyl to the glucosamine disaccharide in lipid A biosynthesis YP_002039469.1 'catalyzes the formation of lipid A disaccharide from UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate, lipid A disaccharide is a precursor of lipid A that anchors LPS to the OM' YP_002039470.1 RNH2; RNase HII; binds manganese; endonuclease which specifically degrades the RNA of RNA-DNA hybrids YP_002039471.1 catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase YP_002039472.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits; one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein YP_002039473.1 identified by match to protein family HMM PF00182; match to protein family HMM PF00801 YP_002039474.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002039475.1 identified by match to protein family HMM PF00903 YP_002039476.1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU; ATP-dependent; responsible for modifying the wobble-base of the CAU anticodon of tRNAIle such that it exhibits proper recognition of the AUA codon rather than the AUG codon and is in turn properly recognized by isoleucyl-tRNA synthetase YP_002039477.2 identified by match to protein family HMM PF07073 YP_002039478.1 identified by match to protein family HMM PF06786 YP_002039479.1 identified by match to protein family HMM PF07152 YP_002039480.1 identified by match to protein family HMM PF00472 YP_002039481.1 identified by match to protein family HMM PF04170 YP_002039482.1 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) YP_002039483.1 identified by match to protein family HMM PF01980; match to protein family HMM TIGR00104 YP_002039485.1 identified by match to protein family HMM PF03180; match to protein family HMM TIGR00363 YP_002039486.1 part of the MetNIQ methionine uptake system YP_002039487.1 part of the metNIQ transport system for methionine YP_002039488.1 'Converts the D-glycero-beta-D-manno-heptose 1,7-bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1-phosphate' YP_002039489.1 'catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid' YP_002039490.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039491.1 identified by match to protein family HMM PF07690 YP_002039492.1 identified by match to protein family HMM PF03372 YP_002039493.1 identified by match to protein family HMM PF01209; match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002039494.2 'catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues; may play a role in recycling muropeptides during cell division and/or cell elongation; in Helicobacter pylori MltD is a endolytic transglycosylase involved mainly in the rearrangement of the peptidoglycan layer of the bacterial cell wall' YP_002039495.1 catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione; plays an important role in cellular detoxification using glutathione YP_002039496.1 identified by match to protein family HMM PF08241 YP_002039497.1 An endonuclease that specifically degrades the RNA strand of RNA-DNA hybrids YP_002039498.1 3'-5' exonuclease of DNA polymerase III YP_002039499.1 identified by match to protein family HMM PF06812 YP_002039500.1 identified by match to protein family HMM PF06996; match to protein family HMM TIGR03347 YP_002039501.1 identified by match to protein family HMM PF05947; match to protein family HMM TIGR03359 YP_002039502.1 identified by match to protein family HMM PF04965; match to protein family HMM TIGR03357 YP_002039503.1 identified by match to protein family HMM PF07024 YP_002039505.1 identified by glimmer YP_002039506.1 identified by match to protein family HMM PF00004; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03345 YP_002039507.1 identified by match to protein family HMM PF05591; match to protein family HMM TIGR03358 YP_002039508.1 identified by match to protein family HMM PF05943; match to protein family HMM TIGR03355 YP_002039510.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002039513.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002039514.2 identified by match to protein family HMM TIGR03352 YP_002039515.1 identified by match to protein family HMM PF05936; match to protein family HMM TIGR03353 YP_002039516.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR03349; match to protein family HMM TIGR03350 YP_002039519.1 identified by match to protein family HMM PF06744; match to protein family HMM PF06761; match to protein family HMM TIGR03348 YP_002039525.1 identified by glimmer YP_002039526.1 identified by match to protein family HMM PF04524; match to protein family HMM TIGR01646; match to protein family HMM TIGR03361 YP_002039527.1 identified by match to protein family HMM PF08786 YP_002039528.1 identified by match to protein family HMM PF03527; match to protein family HMM PF05488; match to protein family HMM PF05593; match to protein family HMM TIGR01643 YP_002039530.1 identified by glimmer YP_002039532.1 identified by match to protein family HMM PF08845 YP_002039533.1 identified by glimmer YP_002039536.1 identified by glimmer YP_002039538.1 identified by glimmer YP_002039541.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039542.1 identified by match to protein family HMM PF00577 YP_002039543.1 identified by match to protein family HMM PF05775 YP_002039544.1 identified by match to protein family HMM PF01522 YP_002039546.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039549.1 identified by glimmer YP_002039550.1 identified by match to protein family HMM PF07813 YP_002039551.1 identified by match to protein family HMM PF00795 YP_002039552.1 catalyzes the isomerization of sedoheptulose 7-phosphate to D-glycero-D-manno-heptose 7-phosphate YP_002039553.1 identified by match to protein family HMM PF00310 YP_002039554.1 identified by match to protein family HMM PF06104 YP_002039555.1 involved in translesion DNA polymerization with beta clamp of polymerase III; belongs to Y family of polymerases; does not contain proofreading function YP_002039556.1 mutations in this gene result in a compromised ability for drug-inducible mexXY expression; expression is inducible by the same ribosome-targeting agents that induce mexXY YP_002039557.1 similar to release factor 1 and 2 YP_002039558.1 identified by match to protein family HMM PF01546; match to protein family HMM PF07687; match to protein family HMM TIGR01893 YP_002039559.1 'catalyzes the conversion of guanine, xanthine and, to a lesser extent, hypoxanthine to GMP, XMP and IMP, respectively' YP_002039560.1 forms a 1:1 complex with the unphosphorylated from of enzyme IIAGlc; FrsA may promote fermentation YP_002039561.1 involved in the expression of csgBA which is involved in curli formation; interacts with sigmaS YP_002039562.1 identified by match to protein family HMM PF00267 YP_002039565.1 catalyzes the formation of glutamate 5-phosphate from glutamate in proline biosynthesis YP_002039566.1 Catalyzes the phosphorylation of L-glutamate during the proline biosynthesis pathway YP_002039568.2 identified by match to protein family HMM PF07690 YP_002039569.1 'dehydratase component, catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate' YP_002039570.1 identified by match to protein family HMM PF00694; match to protein family HMM TIGR00171 YP_002039571.1 identified by match to protein family HMM PF01557 YP_002039572.1 identified by match to protein family HMM PF00561 YP_002039573.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039575.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039576.1 identified by match to protein family HMM PF00419 YP_002039577.1 identified by match to protein family HMM PF00577 YP_002039578.1 identified by match to protein family HMM PF00345 YP_002039581.1 identified by match to protein family HMM PF00563 YP_002039582.1 identified by match to protein family HMM PF00486 YP_002039584.1 identified by match to protein family HMM PF06316; match to protein family HMM TIGR03304 YP_002039587.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01845 YP_002039588.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002039589.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002039590.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002039591.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR02044 YP_002039594.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002039595.1 identified by match to protein family HMM PF01555 YP_002039596.1 identified by match to protein family HMM PF04851; match to protein family HMM PF08774 YP_002039597.1 identified by glimmer YP_002039598.1 identified by match to protein family HMM PF01654 YP_002039599.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002039601.1 identified by match to protein family HMM PF00165 YP_002039602.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002039603.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002039604.1 identified by match to protein family HMM PF07338 YP_002039605.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF06506; match to protein family HMM TIGR02329 YP_002039606.1 catalyzes the formation of pyruvate and succinate from 2-methylisocitrate YP_002039607.1 catalyzes the synthesis of 2-methylcitrate from propionyl-CoA and oxaloacetate; also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity YP_002039608.1 'functions in propionate metabolism; involved in isomerization of (2S,3S)-methylcitrate to (2R,3S)-methylisocitrate; also encodes minor aconitase or dehydratase activity; aconitase C' YP_002039609.1 'catalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent' YP_002039610.1 catalyzes the formation of porphobilinogen from 5-aminolevulinate YP_002039611.1 identified by glimmer YP_002039612.1 identified by glimmer YP_002039613.2 identified by match to protein family HMM PF03212; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002039614.1 this protein has no known enzymatic function YP_002039615.1 'in Escherichia coli SbmA is involved in uptake of microcin J25; functions along with FhuA, TonB, and ExbB/D in this capacity; in Sinorhizobium meliloti, BacA is essential and required for symbiosis; defects appear to affect the cell envelope' YP_002039616.1 identified by match to protein family HMM PF07759 YP_002039619.1 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli YP_002039620.1 identified by match to protein family HMM PF06904 YP_002039621.1 identified by match to protein family HMM PF07690 YP_002039623.1 identified by match to protein family HMM PF07769 YP_002039624.1 'catalyzes the conversion of 2 GTP into c-di-GMP; adrA overexpression induces cellulose biosynthesis, cell adherence to abiotic surfaces and swimming and swarming motility; AdrA acts post-transcriptionally on the bcsABZC operon activating cellulose biosynthesis' YP_002039625.1 catalyzes the formation of L-proline from pyrroline-5-carboxylate YP_002039626.1 identified by glimmer YP_002039627.1 identified by match to protein family HMM PF02639 YP_002039628.1 type II enzyme similar to type I but differentially regulated and with a lower Km; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002039630.1 identified by match to protein family HMM PF07302 YP_002039631.1 identified by match to protein family HMM PF06865 YP_002039632.1 Required for efficient pilin antigenic variation YP_002039633.1 catalyzes phosphorylation of fructose; cytosolic enzyme YP_002039634.1 member of the major facilitator superfamily (MFS) of transporters; unknown function; may be associated with transport or processing of arabinose polymers YP_002039635.1 with SbcD cleaves DNA hairpin structures; also has 5' single-strand endonuclease activity YP_002039636.1 'with SbcC cleaves DNA hairpin structure, also has 5' single-strand endonuclease activity' YP_002039637.1 two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB YP_002039638.1 membrane-associated histidine protein kinase that phosphorylates phoB in response to environmental signals as part of the two-component phosphate regulatory system phoR/phoB YP_002039640.1 identified by match to protein family HMM PF05525; match to protein family HMM TIGR00796 YP_002039641.1 'cryptic permease that may be involved in the transport of proline across the inner membrane; in Salmonella typhimurium, the proY gene is silent unless overexpressed on a multicopy plasmid or activated by a proZ mutation' YP_002039642.1 identified by match to protein family HMM PF00128 YP_002039643.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002039644.1 Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP YP_002039645.1 Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step YP_002039647.1 'Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr)' YP_002039648.1 member of preprotein translocase; forms a heterotrimer with SecD and SecF; links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex YP_002039649.1 'part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane' YP_002039650.1 'forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF' YP_002039651.1 identified by match to protein family HMM PF00903 YP_002039652.1 identified by match to protein family HMM PF08279 YP_002039653.1 identified by match to protein family HMM PF01844 YP_002039654.1 identified by match to protein family HMM PF03502 YP_002039656.1 identified by glimmer YP_002039657.1 identified by match to protein family HMM PF03477; match to protein family HMM TIGR00244 YP_002039658.1 'riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil' YP_002039659.1 'RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not' YP_002039660.1 Regulates rRNA biosynthesis by transcriptional antitermination YP_002039661.1 catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP YP_002039662.1 hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate YP_002039663.1 identified by match to protein family HMM PF00248 YP_002039664.1 catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate YP_002039665.1 identified by match to protein family HMM PF00348 YP_002039666.1 catalyzes the bidirectional exonucleolytic cleavage of DNA YP_002039667.1 Required for the synthesis of the thiazole moiety YP_002039668.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03255 YP_002039669.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR03226 YP_002039670.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08402; match to protein family HMM TIGR03258 YP_002039671.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR03227 YP_002039672.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR03337 YP_002039673.1 catalyzes the formation of phosphonoacetaldehyde from 2-aminoethylphosphonate and pyruvate YP_002039674.1 catalyzes the degradation of phosphonoacetaldehyde to acetaldehyde and phosphate YP_002039675.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01383 YP_002039676.1 ketopantoate reductase; catalyzes the NADPH reduction of ketopantoate to pantoate; functions in pantothenate (vitamin B5) biosynthesis YP_002039677.1 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ; the YajQ protein from Pseudomonas synringae appears to play a role in activation of bateriophage phi6 segment L transcription YP_002039678.1 identified by match to protein family HMM PF07690 YP_002039679.1 identified by match to protein family HMM PF08238 YP_002039680.1 identified by match to protein family HMM PF08238 YP_002039681.1 converts protoheme IX and farnesyl diphosphate to heme O YP_002039682.1 identified by match to protein family HMM PF03626; match to protein family HMM TIGR02847 YP_002039683.1 identified by match to protein family HMM PF00510; match to protein family HMM TIGR02842 YP_002039684.1 identified by match to protein family HMM PF00115; match to protein family HMM TIGR02843 YP_002039685.1 identified by match to protein family HMM PF00116; match to protein family HMM PF06481; match to protein family HMM TIGR01433 YP_002039686.1 identified by glimmer YP_002039687.1 in Escherichia coli this protein is a permease involved in peptidoglycan recycling; member of major facilitator superfamily; MFS; inner membrane protein YP_002039688.1 identified by glimmer YP_002039689.1 'positive transcriptional regulator of morphogenetic pathway; controlling several genes involved in oxidative stress, acid stress, heat shock, osmotic shock, and carbon-starvation stress' YP_002039690.1 Tig; RopA; peptidyl-prolyl cis/trans isomerase; promotes folding of newly synthesized proteins; binds ribosomal 50S subunit; forms a homodimer YP_002039691.1 'hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates' YP_002039692.1 binds and unfolds substrates as part of the ClpXP protease YP_002039693.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02190; match to protein family HMM PF05362; match to protein family HMM PF07728; match to protein family HMM TIGR00763 YP_002039694.1 histone-like DNA-binding protein YP_002039695.1 identified by match to protein family HMM PF00639 YP_002039696.1 identified by match to protein family HMM TIGR00426 YP_002039697.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00051 YP_002039698.1 'YbaX; catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0), as one of the early reactions of quenosine biosynthesis; quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn, Asp, Tyr, and His' YP_002039699.1 identified by match to protein family HMM PF00496 YP_002039700.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002039701.1 identified by match to protein family HMM PF00291 YP_002039702.1 identified by match to protein family HMM PF01037 YP_002039703.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002039704.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002039706.1 'indirectly regulates nitrogen metabolism; at high nitrogen levels P-II 2 prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II 2 is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; functionally it is equivalent to protein P-II (GlnB), but itsexpression is driven by the presence of uridylyltransferase, nitrogen regulator I, and the absence of ammonia.' YP_002039707.1 identified by match to protein family HMM PF00909; match to protein family HMM TIGR00836 YP_002039708.1 identified by match to protein family HMM PF02551; match to protein family HMM TIGR00189 YP_002039710.1 identified by match to protein family HMM PF01035; match to protein family HMM TIGR00589 YP_002039711.1 identified by match to protein family HMM PF00563 YP_002039712.1 'RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome' YP_002039713.1 smallest protein in the large subunit; similar to what is found with protein L31 and L33 several bacterial genomes contain paralogs which may be regulated by zinc; the protein from Thermus thermophilus has a zinc-binding motif and contains a bound zinc ion; the proteins in this group do not have the motif YP_002039715.1 identified by match to protein family HMM PF00132 YP_002039716.1 with Hns involved in transcriptional regulation of hemolysin; non-specific DNA-binding protein which affects the production of multiple proteins YP_002039718.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002039719.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002039720.1 regulates the acrAB operon which is involved in susceptibility to dephalothin and cephaloridine YP_002039721.1 small mechanosensitive ion channel (MscS) that opens in response to stretch forces in the membrane lipid bilayer; maintains cell turgor through accumulation and release of potassium; large protein class of MscS YP_002039722.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002039724.1 'PriC; protein involved in DNA replication; part of the primosome, a protein complex required to restart stalled replication forks; binds the complex formed by PriA, PriB and DNA; PriC-dependent primosome requires a gap to restart DNA replication; stimulates Rep activity at stalled forks' YP_002039725.1 identified by match to protein family HMM PF04304 YP_002039726.1 catalyzes a salvage reaction resulting in the formation of AMP which is metabolically less costly than a de novo synthesis YP_002039727.1 'catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the tau chain serves as a scaffold to help in the dimerizaton of the alpha,epsilon and theta core complex; the gamma chain seems to interact with the delta and delta' subunits to transfer the beta subunit on the DNA' YP_002039728.1 identified by match to protein family HMM PF02575; match to protein family HMM TIGR00103 YP_002039729.1 'involved in a recombinational process of DNA repair, independent of the recBC complex' YP_002039730.1 molecular chaperone YP_002039731.1 essential enzyme that recycles AMP in active cells; converts ATP and AMP to two molecules of ADP YP_002039733.1 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic YP_002039734.1 identified by match to protein family HMM PF07859 YP_002039735.1 identified by match to protein family HMM PF00294 YP_002039736.1 YbaL; member of the CPA-2 family of antiporters; uncharacterized protein YP_002039737.1 identified by glimmer YP_002039738.1 identified by match to protein family HMM PF07690 YP_002039739.1 'catalyzes the degradation of periplasmic UDP-glucose to uridine, glucose-1-phosphate and inorganic phosphate; specific for uridine nucleotides' YP_002039740.1 identified by match to protein family HMM PF04073; match to protein family HMM TIGR00011 YP_002039741.1 identified by match to protein family HMM PF07446 YP_002039743.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525 YP_002039744.1 activator of copper-responsive regulon genes YP_002039745.1 identified by match to protein family HMM PF01957 YP_002039746.1 identified by match to protein family HMM PF01145 YP_002039747.1 identified by match to protein family HMM PF00005 YP_002039748.1 identified by match to protein family HMM PF03649; match to protein family HMM TIGR00245 YP_002039749.1 identified by match to protein family HMM PF00085 YP_002039750.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002039751.1 identified by match to protein family HMM PF00657 YP_002039752.1 identified by match to protein family HMM PF00005 YP_002039753.1 identified by match to protein family HMM PF02687 YP_002039755.1 identified by match to protein family HMM PF03180 YP_002039756.1 identified by match to protein family HMM PF00005; match to protein family HMM PF09383 YP_002039757.1 identified by match to protein family HMM PF00528 YP_002039758.1 catalyzes the selenophosphate-dependent transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA YP_002039759.1 activator of the allDC-ylbA operon involved in allantoin utilization YP_002039760.1 catalyzes the formation of glyoxylate from (S)-ureidoglycolate YP_002039761.1 regulates operons involved in the utilization of allantoin YP_002039762.1 catalyzes the formation of 2-hydroxy-3-oxopropanoate (tartronate semialdehyde) from two molecules of glyoxylate YP_002039763.1 identified by match to protein family HMM PF01261; match to protein family HMM TIGR03234 YP_002039764.1 identified by match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR01505 YP_002039765.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002039766.1 identified by match to protein family HMM PF02133; match to protein family HMM TIGR00800 YP_002039767.1 Plays a crucial role on both purine and pyrimidine metabolism YP_002039768.1 identified by match to protein family HMM PF00860 YP_002039769.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002039770.1 identified by match to protein family HMM PF05899; match to protein family HMM PF07883; match to protein family HMM TIGR03214 YP_002039771.1 'allantoate amidohydrolase and N-carbamoyl-L-amino acid amidohydrolase are very similar; the allantoate amidohydrolase from Escherichia coli forms a dimer and binds zinc ions for catalytic activity and catalyzes the conversion of allantoate to (S)-ureidoglycolate and ammonia; carbamoyl amidohydrolase from Bacillus sp. converts N-carbamoyl amino acids to amino acids, ammonia, and carbon dioxide' YP_002039772.1 identified by match to protein family HMM PF02615; match to protein family HMM TIGR03175 YP_002039773.1 multicopy suppressor of dominant negative ftsH mutations YP_002039774.1 identified by match to protein family HMM PF06545 YP_002039776.1 identified by match to protein family HMM PF00696; match to protein family HMM TIGR00746 YP_002039777.1 With PurE catalyzes the conversion of aminoimidazole ribonucleotide to carboxyaminoimidazole ribonucleotide in the de novo purine nucleotide biosynthetic pathway YP_002039778.1 identified by match to protein family HMM PF00731; match to protein family HMM TIGR01162 YP_002039779.1 'catalyzes the formation of 2,3=diacylglucosamine 1-phosphate from UDP-2,3=diacylglucosamine' YP_002039780.1 identified by match to protein family HMM PF00160 YP_002039781.1 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA YP_002039784.1 identified by match to protein family HMM PF04307 YP_002039786.1 'catalyzes the formation of 5,10-methenyltetrahydrofolate from 5,10-methylenetetrahydrofolate and subsequent formation of 10-formyltetrahydrofolate from 5,10-methenyltetrahydrofolate' YP_002039787.1 identified by match to protein family HMM PF00419 YP_002039788.1 identified by match to protein family HMM PF00419 YP_002039789.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002039790.1 identified by match to protein family HMM PF00577 YP_002039792.1 identified by match to protein family HMM PF00419 YP_002039793.1 activates the production of the major fimbrae protein FimA YP_002039798.1 identified by match to protein family HMM PF00535 YP_002039799.1 identified by match to protein family HMM PF04138 YP_002039800.1 identified by glimmer YP_002039802.1 identified by match to protein family HMM PF00165 YP_002039803.1 Involved in disulfide oxidoreductase activity and electron transport YP_002039804.1 identified by glimmer YP_002039805.1 identified by match to protein family HMM PF07338 YP_002039806.1 identified by match to protein family HMM PF04224 YP_002039808.1 identified by match to protein family HMM PF00324 YP_002039809.1 identified by match to protein family HMM PF00924 YP_002039811.1 identified by match to protein family HMM PF00657; match to protein family HMM PF03797; match to protein family HMM TIGR01414 YP_002039812.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF07728 YP_002039813.1 identified by match to protein family HMM PF01380 YP_002039814.1 identified by match to protein family HMM PF01380 YP_002039815.1 identified by match to protein family HMM PF03613 YP_002039816.1 identified by match to protein family HMM PF03609 YP_002039817.1 identified by match to protein family HMM PF03830 YP_002039818.1 identified by match to protein family HMM PF03610 YP_002039819.1 'catalyzes the reduction of nitroaromatic compounds such as nitrofurazone, quinones and the anti-tumor agent CB1954; NAD(P)H-dependent; oxygen insensitive' YP_002039820.1 identified by match to protein family HMM PF04237 YP_002039821.1 identified by match to protein family HMM PF00440 YP_002039822.1 identified by match to protein family HMM PF00165 YP_002039824.1 ATP-dependent; carboxylate-amine ligase with weak glutamate--cysteine ligase activity YP_002039825.1 identified by match to protein family HMM PF01648 YP_002039826.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002039827.1 identified by match to protein family HMM PF00756 YP_002039828.1 identified by match to protein family HMM PF03621 YP_002039829.1 'with EntB, EntD, and EntE forms the multienzyme complex enterobactin synthase; EntF is the serine activating enzyme which catalyzes the formation of the amide and ester bonds of the cyclic enterobactin' YP_002039830.1 part of the ferric enterobactin transport system; necessary for enetrobactin uptake YP_002039831.1 with FepBDE is involved in the transport of ferric enterobactin YP_002039832.1 with FepBCD is involved in the transport of ferric enterobactin YP_002039833.1 with FepBCG is involved in the transport of ferric enterobactin YP_002039834.1 protein p43; inner membrane protein that exports enterobactin to the periplasmic space; member of the major facilitator superfamily (MFS) of transporters YP_002039835.1 with FepCDG is involved in the transport of ferric enterobactin YP_002039836.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002039837.1 'bifunctional 2,3-dihydroxybenzoate-AMP ligase/S-dihydroxybenzoyltransferase; activates the carboxylate group of 2,3-dihydroxy-benzoate forming (2,3-dihydroxybenzoyl)adenylate then catalyzes the acylation of holo-entB with 2,3-dihydroxy-benzoate adenylate' YP_002039838.1 identified by match to protein family HMM PF00550; match to protein family HMM PF00857 YP_002039839.1 'catalyzes the formation of 2,3-dihydroxybenzoate from 2,3-dihydro-2,3-dihydroxybenzoate; involved in the biosynthesis of siderophores, enterobactin, bacillibactin or vibriobactin' YP_002039840.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002039841.1 identified by match to protein family HMM PF02554 YP_002039842.1 identified by match to protein family HMM PF04328 YP_002039843.1 member of the iron-containing alcohol dehydrogenase family; unknown function YP_002039844.1 catalyzes the transfer of an amino moiety YP_002039845.1 identified by match to protein family HMM PF02195 YP_002039846.1 identified by match to protein family HMM PF01507 YP_002039847.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039848.2 Involved in disulfide bond formation YP_002039849.1 with AhpF catalyzes the conversion of alkyl hydroperoxides to their corresponding alcohols; AhpC reduced the hydroperoxide substrate YP_002039850.1 identified by match to protein family HMM PF06192 YP_002039851.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568 YP_002039852.1 identified by match to protein family HMM PF00037 YP_002039855.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002039856.1 'Regulates the synthesis of nucleoside triphosphates for nucleic acid synthesis, CTP for lipid synthesis, and GTP for protein elongation' YP_002039858.1 identified by match to protein family HMM PF00939; match to protein family HMM TIGR00785 YP_002039859.1 catalyzes the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA from ATP and 3-dephospho-CoA YP_002039860.1 2'-(5''-phosphoribosyl)-3'-dephospho-CoA transferase; holo-citrate lyase synthase; CitG forms the prosthetic group precursor 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA which is then transferred to apo-ACP by CitX to produce holo-ACP and pyrophosphate YP_002039861.1 identified by match to protein family HMM PF04223; match to protein family HMM TIGR01584 YP_002039862.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR01588 YP_002039863.1 acyl carrier protein; with CitE and CitF catalyzes the formation of oxaloacetate from citrate YP_002039864.1 identified by match to protein family HMM PF00583; match to protein family HMM PF08218; match to protein family HMM TIGR00124; match to protein family HMM TIGR00125 YP_002039866.1 identified by match to protein family HMM PF02518 YP_002039867.1 regulates the expression of citAB in citrate fermentation YP_002039868.1 responsible for the transport of C4-dicarboxylates during anaerobic growth YP_002039869.1 catalyzes the transfer of palmitate to lipid A YP_002039870.1 member of the CspA family; constitutively expressed RNA/ssDNA-binding protein; functions in helping cells adapt to low temperature; aids nucleic acid melting; participates in gene regulation; can act as a transcription antiterminator YP_002039871.1 may be involved in chromosome condensation; overexpression in Escherichia coli protects against decondensation by camphor; overexpressing the protein results in an increase in supercoiling YP_002039872.1 identified by match to protein family HMM PF00795 YP_002039873.1 TatE; similar to TatA and found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002039874.1 catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group YP_002039875.1 identified by glimmer YP_002039876.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039877.1 lipoyl/octanoyltransferase; catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein YP_002039878.1 identified by match to protein family HMM PF04359 YP_002039879.1 penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors YP_002039880.1 identified by match to protein family HMM PF03330; match to protein family HMM PF05036; match to protein family HMM TIGR00413 YP_002039881.1 identified by match to protein family HMM PF01098; match to protein family HMM TIGR02210 YP_002039882.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_002039883.1 SPOUT methyltransferase family protein; crystal structure shows homodimer; in Escherichia coli this protein methylates pseudouridine at position 1915 of the 23S ribosomal RNA YP_002039884.1 identified by match to protein family HMM PF02410; match to protein family HMM TIGR00090 YP_002039885.1 identified by glimmer YP_002039886.1 identified by match to protein family HMM PF00300; match to protein family HMM TIGR03162 YP_002039887.1 'cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase' YP_002039888.1 transfers an adenyl group from ATP to NaMN to form nicotinic acid adenine dinucleotide (NaAD) which is then converted to the ubiquitous compound NAD by NAD synthetase; essential enzyme in bacteria YP_002039889.1 required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA YP_002039890.1 rare lipoprotein B; involved in the assembly of LPS in the outer membrane YP_002039891.1 'leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase' YP_002039892.1 identified by match to protein family HMM PF08666 YP_002039893.1 identified by match to protein family HMM PF04295 YP_002039894.1 transports degraded pectin products into the bacterial cell YP_002039895.1 identified by match to protein family HMM PF00158; match to protein family HMM PF06506 YP_002039896.1 identified by match to protein family HMM PF07295 YP_002039897.1 identified by match to protein family HMM PF08238 YP_002039898.1 identified by match to protein family HMM PF06889 YP_002039899.1 identified by match to protein family HMM PF00226 YP_002039900.1 identified by match to protein family HMM PF06889 YP_002039901.1 identified by match to protein family HMM PF00226 YP_002039902.1 identified by match to protein family HMM PF00012 YP_002039904.1 'Hydrolyzes with equal efficiency cytidine or uridine to ribose and cytosine or uracil, respectively; pyrimidine-specific' YP_002039905.1 identified by match to protein family HMM PF00005 YP_002039906.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002039907.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002039908.1 identified by match to protein family HMM PF00497 YP_002039909.1 identified by glimmer YP_002039910.1 Transfers the fatty acyl group on membrane lipoproteins YP_002039911.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471 YP_002039912.1 identified by match to protein family HMM PF02130; match to protein family HMM TIGR00043 YP_002039913.1 identified by match to protein family HMM PF02562 YP_002039914.1 catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) YP_002039915.1 'catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol; functions in the biosynthesis of ubiquinone or coenzyme Q' YP_002039917.1 'functions in asparagine biosynthesis; converts glutamine, aspartate, ATP, and water to glutamate, asparagine, pyrophosphate and AMP' YP_002039918.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01460 YP_002039919.1 identified by match to protein family HMM PF00480 YP_002039920.1 catalyzes the formation of glucosamine 6-phosphate from N-acetylglucosamine 6-phosphate YP_002039921.1 catalyzes the reversible formation of fructose 6-phosphate from glucosamine 6-phosphate YP_002039922.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002039923.1 'catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002039924.1 identified by match to protein family HMM PF03573 YP_002039926.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002039927.1 identified by match to protein family HMM TIGR02484 YP_002039928.1 catalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica YP_002039929.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002039930.1 negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer YP_002039931.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002039932.1 identified by match to protein family HMM PF01402 YP_002039933.1 identified by glimmer YP_002039934.1 identified by match to protein family HMM PF00561; match to protein family HMM PF07819 YP_002039935.1 negative modulator of the initiation of chromosome replication YP_002039936.1 catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate YP_002039938.1 'catalyzes the uptake of putrescine via a proton symport mechanism, as well as the efflux of putrescine by a putrescine/ornithine antiport system' YP_002039939.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002039941.1 response regulator in two-component regulatory system with KdpD; regulates the kdp operon involved in potassium transport YP_002039942.1 sensory histidine kinase in two-component regulatory system with KdpE; signal sensing protein YP_002039943.1 'One of the components of the high-affinity ATP-driven potassium transport (or KDP)system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex' YP_002039944.1 'One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions' YP_002039945.1 catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions YP_002039947.1 UV-induced DNA repair; converts cyclobutane-type pyrimidine dimers created during exposure to UV ratiation to monomers; light dependent YP_002039948.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002039949.1 identified by match to protein family HMM PF01784; match to protein family HMM TIGR00486 YP_002039950.1 identified by match to protein family HMM PF02682; match to protein family HMM TIGR00370 YP_002039951.1 identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724 YP_002039952.1 identified by match to protein family HMM PF03746 YP_002039954.1 identified by match to protein family HMM PF00589 YP_002039957.1 identified by match to protein family HMM PF03275; match to protein family HMM TIGR00031 YP_002039958.1 identified by match to protein family HMM PF00535 YP_002039959.1 identified by match to protein family HMM PF00534 YP_002039960.1 identified by match to protein family HMM PF01061 YP_002039961.1 identified by match to protein family HMM PF00005 YP_002039966.1 5-formyluracil/5-hydroxymethyluracil DNA glycosylase; involved in base excision repair of DNA damaged by oxidation or by mutagenic agents; acts as DNA glycosylase that recognizes and removes damaged bases with a preference for oxidized pyrimidines; has apurinic/apyrimidinic lyase activity YP_002039967.1 identified by match to protein family HMM PF05145; match to protein family HMM TIGR03082 YP_002039968.1 'type II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH' YP_002039969.1 identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970 YP_002039970.1 identified by match to protein family HMM TIGR02968 YP_002039971.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol YP_002039972.1 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase YP_002039973.1 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide YP_002039974.1 component of 2-oxoglutarate dehydrogenase complex; catalyzes the transfer of succinyl coenzyme A to form succinyl CoA as part of the conversion of 2-oxoglutarate to succinyl-CoA YP_002039975.1 catalyzes the interconversion of succinyl-CoA and succinate YP_002039976.1 Catalyzes the only substrate-level phosphorylation in the TCA cycle YP_002039977.1 identified by glimmer YP_002039978.1 identified by glimmer YP_002039979.1 identified by glimmer YP_002039981.1 identified by match to protein family HMM PF01654 YP_002039982.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002039983.1 identified by match to protein family HMM PF08173; match to protein family HMM TIGR02106 YP_002039984.1 identified by match to protein family HMM PF09600; match to protein family HMM TIGR02112 YP_002039985.1 catalyzes the hydrolysis of short chain aliphatic acyl-CoA thioesters; physiological role remains unknown; involved in phospholipid metabolism; part of the Tol/Pal system of proteins that are critical for maintaining the integrity of the cell envelope components YP_002039986.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002039987.1 membrane spanning protein in TolA-TolQ-TolR complex; involved in the tonB-independent uptake of group A colicins YP_002039988.1 'inner membrane component of 7 member Tol-Pal envelope-spanning complex; involved in maintaining cell envelope integrity; utilized by colicins and filamentous phages for import; interacts with TolB, Pal, and through TolB to various outer membrane porins' YP_002039989.1 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA YP_002039990.1 identified by match to protein family HMM PF00691; match to protein family HMM TIGR02802 YP_002039991.1 periplasmic protein that interacts with TolA; the tol-pal system is probably involved in maintaining cell envelope integrity YP_002039992.1 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate YP_002039993.1 identified by match to protein family HMM PF04973; match to protein family HMM TIGR01528 YP_002039994.1 involved in zinc efflux across the cytoplasmic membrane YP_002039996.1 'catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, phenylalanine sensitive' YP_002039997.1 identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723 YP_002039998.1 Catalyzes the reversible hydration of fumaric acid to yield I-malic acid YP_002039999.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040000.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040001.1 identified by match to protein family HMM PF00939; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002040002.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002040003.1 catalyzes the formation of pyruvate from oxaloacetate YP_002040004.1 identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109 YP_002040006.1 identified by match to protein family HMM PF01032 YP_002040007.1 identified by match to protein family HMM PF00005 YP_002040008.1 '2,3-bisphosphoglycerate-dependent; catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate' YP_002040009.1 'catalyzes the conversion of alpha-aldose to the beta-anomer; active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose; links the metabolism of lactose and galactose' YP_002040010.1 catalyzes the formation of alpha-D-galactose 1-phosphate from D-galactose in galactose metabolism YP_002040011.1 catalyzes the interconversion of UDP-galactose and galactose-1-P with UDP-galactose and glucose-1-P YP_002040012.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01179 YP_002040014.1 contains 2 ATP-binding cassettes; involved in the transport of molybdenum YP_002040015.1 represses the modABCD operon and activates the moaABCD and napFDAGHBC operons YP_002040017.1 with ModCB is involved in the high-affinity transport of molybdate YP_002040018.1 part of ModCBA molybdate transporter; member of ABC superfamily; inner membrane component; regulated by repressor protein ModE YP_002040019.1 Part of the ABC transporter complex modABC involved in molybdenum import YP_002040020.1 'YbhA; catalyzes the dephosphorylation of pyridoxal phosphate, fructose 1,6-bisphosphate, erythrose 4-phosphate and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; phosphotransferase activity observed when using monophosphates as phosphate donor; member of the haloacid dehalogenase-like hydrolases superfamily' YP_002040021.1 catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate YP_002040022.1 outer membrane lipoprotein that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA; YbhC localizes to the cellular poles; member of pectinesterase family YP_002040023.1 'catalyzing the hydrolysis of 4-imidazolone-5-propionate to N-formimidoyl-L-glutamate, the third step in the histidine degradation pathway' YP_002040024.1 catalyzes the formation of glutamate and formamide from N-formimidoyl-L-glutamate YP_002040025.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702; match to protein family HMM TIGR02018 YP_002040026.1 catalyzes the formation of 4-imidazolone-5-propanoate from urocanate during histidine metabolism YP_002040027.1 catalyzes the degradation of histidine to urocanate and ammmonia YP_002040028.1 YbhB; similar to rat and human kinase inhibitory proteins YP_002040029.1 'catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7,8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate' YP_002040030.1 identified by match to protein family HMM PF04055; match to protein family HMM PF06968; match to protein family HMM TIGR00433 YP_002040031.1 catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine YP_002040032.1 'methyltransferase; acyl carrier protein involved in an unidentified step in the synthesis of pimeloyl-CoA, a biotin precursor; member of the bio operon (bioABFCD); in Escherichia coli, bioC-null mutants require biotin for growth' YP_002040033.1 'DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium' YP_002040034.1 'The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion' YP_002040036.1 identified by match to protein family HMM PF01933; match to protein family HMM TIGR01826 YP_002040037.1 'together with moaC, is involved in the conversion of a guanosine derivative (GXP) into molybdopterin precursor Z' YP_002040038.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR02667 YP_002040039.1 MoaC; along with MoaA is involved in conversion of a guanosine derivative into molybdopterin precursor Z; involved in molybdenum cofactor biosynthesis YP_002040040.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002040041.1 catalyzes the conversion of molybdopterin precursor Z into molybdopterin YP_002040042.1 identified by match to protein family HMM PF01027 YP_002040047.1 identified by match to protein family HMM PF00614 YP_002040048.1 identified by match to protein family HMM PF03372 YP_002040050.1 identified by match to protein family HMM PF01061 YP_002040051.1 identified by match to protein family HMM PF01061 YP_002040052.1 identified by match to protein family HMM PF00005 YP_002040053.1 identified by match to protein family HMM PF00529 YP_002040054.1 identified by match to protein family HMM PF00440; match to protein family HMM PF09209 YP_002040055.1 this helicase is not essential cell growth YP_002040056.1 helicase involved in DNA repair and perhaps also replication YP_002040057.1 identified by match to protein family HMM PF02885 YP_002040058.1 identified by match to protein family HMM PF07338 YP_002040061.1 identified by match to protein family HMM PF01258 YP_002040062.1 identified by match to protein family HMM PF05971 YP_002040063.1 identified by match to protein family HMM PF00924 YP_002040064.1 similar to ATP-binding component of ABC transporters YP_002040065.1 similar to permease component of ABC transporters; mutations impair ability of Escherichia coli to transport and utilize glutamine YP_002040066.1 similar to periplasmic-binding component of ABC transporters YP_002040067.1 identified by glimmer YP_002040068.1 binds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage YP_002040070.1 identified by match to protein family HMM PF00892 YP_002040071.1 OmpX; involved in cell adhesion; forms an eight-stranded antiparallel beta-barrel that protrudes from the cell surface; mutations in the gene increase cell-surface contact in fimbriated strains but decrease contact in nonfimbriated strains YP_002040072.1 identified by match to protein family HMM PF00884 YP_002040073.1 identified by glimmer YP_002040074.1 Transcriptional regulator that represses the manganese transporter MntH when manganese is present YP_002040075.1 identified by match to protein family HMM PF03600 YP_002040076.1 identified by match to protein family HMM PF03734 YP_002040077.1 identified by match to protein family HMM PF00005 YP_002040079.1 identified by match to protein family HMM PF08282 YP_002040080.1 identified by match to protein family HMM PF07350 YP_002040081.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002040082.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01774 YP_002040083.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002040084.1 'ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase' YP_002040085.1 is involved in the formation of active molybdenum cofactor and the chelation of molybdenum YP_002040086.1 identified by match to protein family HMM PF01112 YP_002040087.1 with GsiBCD is involved in glutathione import; GsiA contains 2 ATP-binding domains YP_002040088.1 identified by match to protein family HMM PF00496 YP_002040089.1 identified by match to protein family HMM PF00528 YP_002040090.1 identified by match to protein family HMM PF00528 YP_002040091.1 catalyzes the methylthiolation of an aspartic acid residue of the S12 protein of the 30S ribosomal subunit YP_002040092.1 identified by glimmer YP_002040093.1 'BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing' YP_002040094.1 identified by glimmer YP_002040096.1 identified by match to protein family HMM PF01012 YP_002040097.1 identified by match to protein family HMM PF00766; match to protein family HMM PF01012 YP_002040098.1 identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028 YP_002040099.1 identified by match to protein family HMM PF01266; match to protein family HMM PF05187 YP_002040100.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040102.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002040103.1 'penicillin-binding protein 6a; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002040104.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002040105.1 identified by match to protein family HMM PF01569 YP_002040106.1 identified by match to protein family HMM PF07690 YP_002040107.1 identified by match to protein family HMM PF00702; match to protein family HMM PF05116; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002040108.1 identified by match to protein family HMM PF07690 YP_002040109.1 identified by match to protein family HMM PF00440 YP_002040110.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002040112.1 functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase YP_002040113.1 YbjC; located in the same operon as the nfsA gene; member of the soxRS regulon which mediates in part the increased levels of superoxide in response to oxidative stress; induced by paraquat; regulated by SoxS; unknown function YP_002040114.1 NADPH-dependent; oxygen-insensitive; catalyzes the reduction of nitroaromatic compounds YP_002040115.1 responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 YP_002040117.1 identified by match to protein family HMM PF01547 YP_002040118.1 part of the PotFGHI ATP-dependent putrescine transporter YP_002040119.1 identified by match to protein family HMM PF00528 YP_002040120.1 identified by match to protein family HMM PF00528 YP_002040122.1 RNA uridine methyltransferase B; catalyzes the formation of 5-methyl-uridine at position 747 in 23S rRNA YP_002040123.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002040124.1 identified by match to protein family HMM PF00884 YP_002040125.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002040126.1 with ArtPQJI acts to transport arginine across the inner membrane YP_002040127.1 with ArtPMJI transports arginine across the inner membrane YP_002040128.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002040129.1 With ArtMQJI transports arginine across the inner membrane YP_002040130.1 induced during stationary phase and by acivicin (a glutamine analog); regulated by Lrp and RpoS YP_002040131.1 identified by match to protein family HMM PF01906 YP_002040132.1 identified by match to protein family HMM PF01510 YP_002040133.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002040134.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF05368 YP_002040135.1 'low- specificity; catalyzes the formation of acetaldehyde and glycine from L-threonine; acts on L-threonine, L-allo-threonine, L-threo-phenylserine, and L-erythro-phenylserine' YP_002040136.1 catalyzes the formation of acetate from pyruvate YP_002040137.1 identified by match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002040138.1 catalyzes the reduction of hydroxylamine to ammonia and water YP_002040139.1 identified by match to protein family HMM PF03956 YP_002040141.1 identified by match to protein family HMM PF04393 YP_002040142.1 confers macrolide resistance via active drug efflux YP_002040143.1 with MacA is involved in the export of macrolide YP_002040144.1 identified by match to protein family HMM PF00313; match to protein family HMM TIGR02381 YP_002040145.1 involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation; binds to the N-terminal domain of the chaperone ClpA YP_002040146.1 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates YP_002040149.1 identified by match to protein family HMM PF00857 YP_002040150.1 identified by match to protein family HMM PF02678; match to protein family HMM PF05726 YP_002040151.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040152.1 'stimulates the activities of the other two initiation factors, IF-2 and IF-3' YP_002040153.1 'leucyltransferase; phenylalanyltransferse; functions in the N-end rule pathway; transfers Leu, Phe, Met, from aminoacyl-tRNAs to N-terminal of proteins with Arg or Lys' YP_002040154.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002040155.1 in Escherichia coli the CydCD ABC transporter exports cysteine and glutathione into the periplasm in order to maintain redox balance; important for cytochrome bd and c YP_002040156.1 catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding YP_002040157.1 identified by glimmer YP_002040158.1 mediates a global response to leucine; acts as a regulator for several genes involved in the high-affinity branched-chain amino acid transport system YP_002040159.1 DNA-binding membrane protein required for chromosome resolution and partitioning YP_002040160.1 participates with LolB in the incorporation of lipoprotein into the outer membrane YP_002040161.1 identified by match to protein family HMM PF00004 YP_002040162.1 'catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002040163.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002040164.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002040165.1 identified by match to protein family HMM PF04976 YP_002040166.1 identified by match to protein family HMM PF07690 YP_002040167.1 identified by match to protein family HMM PF00324 YP_002040168.1 activates pyruvate formate-lyase 1 under anaerobic conditions YP_002040171.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002040172.1 identified by match to protein family HMM PF01226; match to protein family HMM TIGR00790 YP_002040173.1 identified by match to protein family HMM PF02624; match to protein family HMM TIGR00702 YP_002040174.1 identified by match to protein family HMM PF04239 YP_002040175.1 catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate; required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine YP_002040176.1 catalyzes the formation of 5-O-(1-carboxyvinyl)-3-phosphoshikimate from phosphoenolpyruvate and 3-phosphoshikimate in tryptophan biosynthesis YP_002040177.1 identified by match to protein family HMM PF01435 YP_002040178.1 Catalyzes the formation of (d)CDP from ATP and (d)CMP YP_002040179.1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins YP_002040180.1 'This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control' YP_002040181.1 identified by match to protein family HMM PF00753; match to protein family HMM PF03772; match to protein family HMM TIGR00360; match to protein family HMM TIGR00361 YP_002040182.1 involved in the transport of lipid A across the inner membrane YP_002040183.1 'transfers the gamma-phosphate of ATP to the 4' position of a tetraacyldisaccharide 1-phosphate intermediate to form tetraacyldisaccharide 1,4'-bis-phosphate' YP_002040184.1 identified by match to protein family HMM PF06224 YP_002040185.1 identified by match to protein family HMM PF03966 YP_002040186.1 CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS YP_002040188.1 identified by match to protein family HMM PF02698 YP_002040189.1 involved in cellular zinc and cadmium homeostasis by binding excess metal ions to its cysteine sulfurs and histidine nitrogens; expression of smtA in cyanobacteria is repressed by SmtB at low concentrations of zinc; NO elicits release of Zn ions from SmtA YP_002040190.1 acts with MukB and MukE to condense the chromosome and allow for segregation during cell division YP_002040191.1 acts with MukB and MukF to condense the chromosome and allow for segregation during cell division YP_002040192.1 SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects YP_002040193.1 identified by match to protein family HMM PF01471 YP_002040194.1 identified by match to protein family HMM PF05951; match to protein family HMM PF08291 YP_002040195.1 identified by match to protein family HMM PF00753 YP_002040196.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002040197.1 identified by match to protein family HMM PF00267 YP_002040198.1 identified by glimmer YP_002040199.1 identified by glimmer YP_002040200.1 'catalyzes a two-step reaction, first charging an asparagine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002040201.1 identified by match to protein family HMM PF01037 YP_002040202.1 identified by glimmer YP_002040203.1 'catalyzes the formation of pyruvate from 2,3-diaminopropionate' YP_002040205.1 identified by match to protein family HMM PF01235; match to protein family HMM TIGR00835 YP_002040206.1 catalyzes the formation of nictonate and 5-phospho-alpha-D-ribose 1-diphosphate from nicotinate D-ribonucleotide and diphosphate YP_002040207.1 identified by match to protein family HMM PF00589 YP_002040208.1 identified by match to protein family HMM PF06806 YP_002040210.1 identified by match to protein family HMM PF03837 YP_002040211.1 identified by match to protein family HMM PF06630 YP_002040214.1 identified by glimmer YP_002040217.1 identified by glimmer YP_002040218.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002040219.1 identified by match to protein family HMM PF01695 YP_002040220.1 identified by match to protein family HMM PF06163 YP_002040222.1 identified by match to protein family HMM PF06183 YP_002040223.1 identified by match to protein family HMM PF07105 YP_002040225.1 identified by match to protein family HMM PF05766 YP_002040228.1 identified by match to protein family HMM PF05106; match to protein family HMM TIGR01594 YP_002040229.1 identified by match to protein family HMM PF00959 YP_002040230.1 identified by match to protein family HMM PF03245 YP_002040231.1 identified by match to protein family HMM PF07278 YP_002040232.1 identified by match to protein family HMM PF05876 YP_002040234.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002040235.1 identified by match to protein family HMM PF00574 YP_002040238.1 identified by match to protein family HMM PF06763 YP_002040239.1 identified by match to protein family HMM PF06141 YP_002040240.1 identified by match to protein family HMM PF02368 YP_002040241.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002040242.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002040243.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002040244.1 identified by match to protein family HMM PF05939 YP_002040245.1 identified by match to protein family HMM PF00080 YP_002040246.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002040247.2 identified by match to protein family HMM PF00877 YP_002040248.2 identified by match to protein family HMM PF06805 YP_002040249.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002040253.2 identified by match to protein family HMM PF03406; match to protein family HMM PF07484 YP_002040254.1 identified by match to protein family HMM PF02413 YP_002040256.1 identified by match to protein family HMM PF02586 YP_002040260.1 identified by match to protein family HMM PF01433; match to protein family HMM TIGR02414 YP_002040261.1 'catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors' YP_002040262.1 identified by match to protein family HMM PF07126 YP_002040263.1 identified by match to protein family HMM PF00111; match to protein family HMM PF03473; match to protein family HMM PF03476 YP_002040264.1 catalyzes the N2-methyl guanosine modification of the G2445 residue of 23S rRNA YP_002040265.1 Uup; in Escherichia coli this cytoplasmic protein was shown to contain ATPase activity; mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth YP_002040266.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002040267.1 identified by match to protein family HMM PF02470 YP_002040268.1 identified by match to protein family HMM PF03886 YP_002040269.1 identified by glimmer YP_002040270.1 'catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2,3-decenoyl-ACP or 3,4-decenoyl-ACP' YP_002040271.1 identified by match to protein family HMM PF05362 YP_002040272.1 identified by match to protein family HMM PF06303 YP_002040273.1 'OmpA is believed to be a porin, involved in diffusion of nonspecific small solutes across the outer membrane. It is the most abundant integral protein of the outer membrane of E. coli, and it is known to play a role as a phage receptor, a mediator of F-factor dependent conjugation, and in maintaining the structural shape of the outer membrane; 3a; II*; G; d' YP_002040274.1 identified by match to protein family HMM PF03846; match to protein family HMM TIGR00623 YP_002040275.1 identified by match to protein family HMM PF04993; match to protein family HMM PF04994 YP_002040276.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01666; match to protein family HMM TIGR01667 YP_002040277.1 identified by match to protein family HMM PF03733 YP_002040278.1 catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand YP_002040279.1 catalyzes the formation of methylglyoxal from glycerone phosphate YP_002040281.1 identified by match to protein family HMM PF08755; match to protein family HMM TIGR02097 YP_002040283.1 identified by match to protein family HMM PF01161; match to protein family HMM TIGR00481 YP_002040284.1 identified by match to protein family HMM PF00165 YP_002040285.1 catalyzes the hydrolysis of acylphosphate YP_002040286.1 transfers sulfur from TusBCD complex to MnmA; involved in thiouridation of U34 position of some tRNAs YP_002040287.1 identified by match to protein family HMM PF01027 YP_002040288.1 identified by glimmer YP_002040289.1 identified by match to protein family HMM PF00589 YP_002040295.1 identified by glimmer YP_002040296.1 identified by glimmer YP_002040300.1 identified by match to protein family HMM PF03796 YP_002040303.1 identified by match to protein family HMM PF05063 YP_002040306.1 identified by match to protein family HMM PF07105 YP_002040307.1 identified by match to protein family HMM PF06576 YP_002040308.1 identified by glimmer YP_002040310.1 identified by match to protein family HMM PF00959 YP_002040312.1 identified by match to protein family HMM PF03245 YP_002040315.1 identified by match to protein family HMM PF09714; match to protein family HMM TIGR01555 YP_002040316.1 identified by match to protein family HMM PF04233; match to protein family HMM TIGR01641 YP_002040328.1 identified by match to protein family HMM PF01464 YP_002040333.1 identified by glimmer YP_002040339.1 identified by match to protein family HMM PF02413 YP_002040340.1 identified by glimmer YP_002040342.1 identified by match to protein family HMM PF07087 YP_002040343.1 identified by glimmer YP_002040345.1 identified by match to protein family HMM PF00805 YP_002040346.1 identified by match to protein family HMM PF07824 YP_002040347.1 identified by match to protein family HMM PF05925 YP_002040349.1 identified by match to protein family HMM PF03577 YP_002040350.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM TIGR01386 YP_002040351.1 induced by CusR in the presence of copper; YedW induces the expression of the upstream gene yedV (encoding a sensor kinase) as well as yedW; yedVW is one of four copper regulons found in E. coli; part of the copper homeostasis mechanism; confers resistance to copper and several drugs when induced YP_002040352.1 identified by match to protein family HMM PF00576; match to protein family HMM TIGR02962 YP_002040353.1 identified by match to protein family HMM PF01613; match to protein family HMM TIGR02296 YP_002040354.1 identified by match to protein family HMM PF03241; match to protein family HMM TIGR02310 YP_002040355.1 identified by match to protein family HMM PF01047; match to protein family HMM TIGR02337 YP_002040356.1 identified by match to protein family HMM PF01557; match to protein family HMM TIGR02303; match to protein family HMM TIGR02305 YP_002040357.1 identified by match to protein family HMM PF00171; match to protein family HMM TIGR02299 YP_002040358.1 identified by match to protein family HMM PF02900; match to protein family HMM TIGR02298 YP_002040359.1 identified by match to protein family HMM PF02962 YP_002040360.1 identified by match to protein family HMM PF01689; match to protein family HMM TIGR02312 YP_002040361.1 identified by match to protein family HMM PF03328; match to protein family HMM TIGR02311 YP_002040362.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR02332 YP_002040363.1 identified by match to protein family HMM PF00165; match to protein family HMM PF02311; match to protein family HMM TIGR02297 YP_002040364.1 identified by match to protein family HMM PF00753 YP_002040366.1 with CpbA modulates the activity of the dnaK chaperone system; interacts with CbpA and inhibits both the DnaJ-like co-chaperone activity and the DNA binding activity of CbpA YP_002040367.1 'functional analog of DnaJ; co-chaperone with DnaK, molecular chaperone in an adaptive response to environmental stresses other than heat shock' YP_002040369.1 identified by match to protein family HMM PF02683 YP_002040370.1 identified by match to protein family HMM PF01323 YP_002040371.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534 YP_002040372.1 identified by match to protein family HMM PF00328 YP_002040374.1 stationary phase protein that binds TrpR repressor YP_002040376.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08362 YP_002040377.1 identified by match to protein family HMM PF07007 YP_002040378.1 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichai coli this protein also self-regulates transcription via a DNA-binding domain at the N-terminus; forms dimers and is a peripherally membrane-associated protein YP_002040379.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; match to protein family HMM TIGR02121 YP_002040380.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002040381.1 identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813 YP_002040382.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002040383.1 identified by match to protein family HMM PF01344; match to protein family HMM PF07646; match to protein family HMM TIGR03547 YP_002040384.1 identified by match to protein family HMM PF06178 YP_002040385.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002040386.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002040387.1 identified by glimmer YP_002040388.1 identified by match to protein family HMM PF02826 YP_002040389.1 identified by match to protein family HMM PF02811 YP_002040390.1 identified by match to protein family HMM PF06192 YP_002040391.1 identified by match to protein family HMM PF06496 YP_002040392.1 identified by match to protein family HMM PF03783 YP_002040393.1 nucleator protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002040394.1 chaperone-like protein that participates in the polymerization of curlin (CsgA) subunits into curli (extracellular fibers from Escherichia and Salmonella spp. that are involved in the colonization of inert surfaces and biofilm formation); part of the curli secretion and assembly protein complex YP_002040395.1 activates the csgBA and csgDEFG operons involved in biofilm formation YP_002040396.1 CsgB; functions as a nucleator in the assembly of curli (coiled surface structures) on the cell surface YP_002040397.1 identified by match to protein family HMM PF07012 YP_002040398.1 involved in autoagglutination of curliated cells; not involved in production of curli fibers YP_002040400.1 identified by match to protein family HMM PF01661 YP_002040401.2 identified by match to protein family HMM PF00614 YP_002040402.1 required for the transfer of succinyl residues to the glucan backbone YP_002040403.1 involved in the biosynthesis of osmoregulated periplasmic glucans; required for the assembly of the polyglucose structure of glucan YP_002040404.1 necessary for biosynthesis of osmoregulated periplasmic glucans possibly involved in the transfer to the periplasmic space YP_002040405.1 identified by match to protein family HMM PF07119 YP_002040407.1 Confers resistance to fosfomycin and deoxycholate YP_002040408.1 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA YP_002040409.1 identified by match to protein family HMM PF00581 YP_002040410.1 identified by match to protein family HMM PF04264 YP_002040411.1 identified by match to protein family HMM PF01292 YP_002040414.1 catalyzes the demethylation of N-methyl-L-tryptophan forming L-tryptophan and formaldehyde; FAD-binding; can also catalyze the demethylation of other N-methyl amino acids YP_002040415.1 'BssS; regulator of biofilm through signal secretion; disruption of this gene in Escherichia coli led to effects on biofilm formation, alteration in expression of a number of genes and mutations in bssS led to defects in indole transport and autoinducer-2 uptake and processing' YP_002040416.1 identified by match to protein family HMM PF06183 YP_002040417.1 catalyzes the formation of N-carbamoyl-L-aspartate from (S)-dihydroorotate in pyrimidine biosynthesis YP_002040418.1 identified by match to protein family HMM PF07273 YP_002040419.1 cofactor involved in the reduction of disulfides YP_002040420.1 Confers resistance to norfloxacin and enoxacin YP_002040421.1 identified by match to protein family HMM PF00583 YP_002040422.1 identified by match to protein family HMM PF04337 YP_002040423.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002040424.1 identified by match to protein family HMM PF03023; match to protein family HMM TIGR01695 YP_002040425.1 identified by match to protein family HMM PF05130 YP_002040426.1 regulates the flagellar specific sigma28 transcription factor YP_002040427.1 required for the assembly of the flagellar basal body P-ring YP_002040428.1 with FlgF and C makes up the proximal portion of the flagellar basal body rod; Vibrio parahaemolyticus protein is associated with the polar flagella YP_002040429.1 with FlgF and B makes up the proximal portion of the flagellar basal body rod YP_002040430.1 'acts as a scaffold for the assembly of hook proteins onto the flagellar basal body rod; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of some flagellar genes; in V. parahaemolyticus one set used for lateral flagella production and the other is used for the polar flagella production' YP_002040431.1 the hook connects flagellar basal body to the flagellar filament YP_002040432.1 'FlgF, with FlgB and C, makes up the proximal portion of the flagellar basal body rod' YP_002040433.1 makes up the distal portion of the flagellar basal body rod YP_002040434.1 'part of the flagellar basal body which consists of four rings L,P, S and M mounted on a central rod' YP_002040435.1 'part of the basal body which consists of four rings L, P, S, and M mounted on a central rod; Vibrio parahaemolyticus, Yersinia, Bradyrhizobium and other bacteria have two copies of this and other flagellar genes; the V. parahaemolyticus protein is associated with the polar flagella and the Bradyrhizobium protein is associated with the thick flagellum' YP_002040436.1 Flagellum-specific muramidase which hydrolyzes the peptidoglycan layer to assemble the rod structure in the periplasmic space YP_002040437.1 with FlgL acts as a hook filament junction protein to join the flagellar filament to the hook YP_002040438.1 'with FlgK acts as a hook filament junction protein to join the flagellar filament to the hook; Yersinia, Vibrio parahaemolyticus, Bradyrhizobium and other organisms have 2 copies of this and other flagellar genes' YP_002040439.1 'bifunctional ribonuclease E/endoribonuclease/RNA-binding protein/RNA degradosome binding protein; forms part of the membrane-associated degradosome complex along with PNPase, RhlB, and enolase' YP_002040440.1 'catalyzes the transformation of uracil to pseudouracil at nucleotides U955, U2504, and U2580 in 23S rRNA' YP_002040443.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002040444.1 identified by match to protein family HMM PF02620 YP_002040445.1 identified by glimmer YP_002040446.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY YP_002040447.1 FabH; beta-ketoacyl-acyl carrier protein synthase III; catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation; differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs YP_002040448.1 identified by match to protein family HMM PF00698; match to protein family HMM TIGR00128 YP_002040449.1 catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis YP_002040450.1 carries the fatty acid chain in fatty acid biosynthesis YP_002040451.1 'FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP' YP_002040452.1 catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate YP_002040453.1 identified by match to protein family HMM PF02618; match to protein family HMM TIGR00247 YP_002040454.1 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP) YP_002040455.1 catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA YP_002040456.1 identified by match to protein family HMM PF01026; match to protein family HMM TIGR00010 YP_002040457.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002040458.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715; match to protein family HMM TIGR01783 YP_002040459.1 identified by match to protein family HMM PF01230 YP_002040460.1 identified by match to protein family HMM PF07233 YP_002040461.1 identified by match to protein family HMM TIGR02722 YP_002040462.1 catalyzes the phosphorylation of thiamine to thiamine phosphate YP_002040463.1 hydrolyzes the terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides YP_002040464.1 identified by match to protein family HMM PF05728 YP_002040465.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01266; match to protein family HMM PF07992 YP_002040466.1 identified by match to protein family HMM PF05433 YP_002040467.1 identified by match to protein family HMM PF00440 YP_002040468.1 identified by match to protein family HMM PF07338 YP_002040469.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002040470.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF02559; match to protein family HMM PF03461; match to protein family HMM PF04851; match to protein family HMM TIGR00580 YP_002040471.1 identified by glimmer YP_002040472.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002040473.1 'outer membrane specific; part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone' YP_002040474.1 part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane YP_002040475.1 catalyzes the formation of N-acetyl-D-glucosamine-6-phosphate from N-acetyl-D-glucosamine YP_002040476.1 Modulates the activities of several enzymes which are inactive in their acetylated form YP_002040477.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotD is a periplasmic component that binds the substrate YP_002040478.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotC is a membrane component YP_002040479.1 identified by glimmer YP_002040480.1 translocated by the type III secretion system SPI-2; required for the formation of lysosomal glycoprotein structures (Sifs); required for maintenance of membrane in the Salmonella-containing vacuole; a cysteine residue with CAAX motif is modified by isoprenoid addition of protein geranylgeranyl transferase I; also modified by S-acylation YP_002040481.1 can transport spermidine and putrescine but affinity is higher for spermidine; forms a complex of PotA2BCD; PotB is a membrane component YP_002040482.1 functions together with PotBCD (A2BCD) in ATP-dependent polyamine transport; PotA is the membrane-associated ATPase YP_002040483.1 catalyzes the release of the N-terminal amino acid from a tripeptide YP_002040484.1 identified by match to protein family HMM PF07719 YP_002040485.1 identified by match to protein family HMM PF08007 YP_002040486.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08918 YP_002040487.1 response regulator in two-component regulatory system with PhoQ; involved in magnesium starvation and stress YP_002040488.1 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide YP_002040489.1 HflD; UPF0274; in Escherichia coli this protein is peripherally associated with the membrane and appears to act with lambda CII protein; in Haemophilus influenzae a knockout of the HI0638 gene affected paracytosis YP_002040490.1 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs YP_002040491.1 identified by match to protein family HMM PF00293 YP_002040493.2 identified by match to protein family HMM PF00849; match to protein family HMM TIGR00093 YP_002040494.1 Converts isocitrate to alpha ketoglutarate YP_002040496.1 identified by glimmer YP_002040498.1 identified by match to protein family HMM PF00652 YP_002040499.1 identified by glimmer YP_002040501.1 identified by match to protein family HMM PF06316 YP_002040502.1 PliC; periplasmic lysozyme inhibitor of c-type lysozyme YP_002040505.1 identified by match to protein family HMM PF00011 YP_002040507.1 identified by match to protein family HMM PF01292 YP_002040509.1 identified by glimmer YP_002040510.1 identified by glimmer YP_002040511.1 identified by match to protein family HMM PF00496 YP_002040512.1 identified by match to protein family HMM PF00528 YP_002040513.1 identified by match to protein family HMM PF00528 YP_002040514.1 identified by match to protein family HMM PF00005 YP_002040515.1 identified by match to protein family HMM PF00005 YP_002040516.1 identified by match to protein family HMM PF00924 YP_002040517.1 identified by match to protein family HMM PF09223 YP_002040518.2 streptomycin 3'-adenyltransferase YP_002040519.1 identified by match to protein family HMM PF00196 YP_002040520.1 identified by match to protein family HMM PF00376 YP_002040522.1 catalyzes the interconversion of chorismate to prephenate YP_002040523.1 identified by match to protein family HMM PF01810 YP_002040524.1 identified by match to protein family HMM PF09313 YP_002040525.1 identified by match to protein family HMM PF08956 YP_002040528.1 identified by match to protein family HMM PF04226 YP_002040530.1 identified by match to protein family HMM PF03891 YP_002040532.1 identified by match to protein family HMM PF04343 YP_002040533.1 identified by glimmer YP_002040534.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00896 YP_002040535.1 identified by match to protein family HMM PF04284 YP_002040537.1 identified by match to protein family HMM PF04073 YP_002040538.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002040539.1 identified by glimmer YP_002040540.1 identified by match to protein family HMM PF04285 YP_002040541.1 identified by glimmer YP_002040542.1 identified by match to protein family HMM PF06798; match to protein family HMM PF08298 YP_002040543.2 identified by match to protein family HMM PF06629 YP_002040545.1 identified by match to protein family HMM PF00248 YP_002040546.1 identified by match to protein family HMM PF01263 YP_002040547.1 identified by match to protein family HMM PF00044; match to protein family HMM PF02800; match to protein family HMM TIGR01534 YP_002040548.1 this stereospecific enzymes reduces the R isomer of methionine sulfoxide while MsrA reduces the S form; provides protection against oxidative stress YP_002040549.1 identified by match to protein family HMM PF07023 YP_002040550.1 catalyzes the formation of nicotinate from nicotinamide in NAD biosynthesis and the formation of pyrazinoate from pyrazinamide YP_002040551.2 converts asparagine to aspartate and ammonia YP_002040552.1 SppA; catalyzes the degradation of cleaved signal peptides; essential to maintain secretion of mature proteins across the membrane YP_002040553.1 identified by match to protein family HMM PF00881 YP_002040554.1 catalyzes the formation of selenophosphate from selenide and ATP YP_002040555.1 decatenates replicating daughter chromosomes YP_002040556.1 converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer YP_002040557.1 identified by match to protein family HMM PF07383 YP_002040558.1 identified by match to protein family HMM PF00293 YP_002040559.1 removes the damaged DNA at cytosines and guanines by cleaving on the 3' side of the AP site by a beta-elimination reaction YP_002040561.1 catalyzes the transamination of 2-N-succinylornithine and alpha-ketoglutarate into 2-N-succinylglutamate semialdehyde and glutamate; also functions as the catabolic acetylornithine aminotransferase catalyzing the formation of 2-N-acetylglutamate semialdehyde and glutamate from 2-N-acetylornithine and alpha-ketoglutarate YP_002040562.1 identified by match to protein family HMM PF04958; match to protein family HMM TIGR03243; match to protein family HMM TIGR03244 YP_002040563.1 a high throughput screen identified this enzyme as an aldehyde dehydrogenase with broad substrate specificity; converts succinylglutamate semialdehyde and NAD to succinylglutamate and NADH YP_002040564.1 'catalyzes the hydrolysis of 2-N-succinylarginine into 2-N-succinylornithine, ammonia and carbon dioxide in arginine degradation' YP_002040565.1 catalyzes the formation of succinate and glutamate from N(2)-succinylglutamate in arginine catabolism YP_002040566.1 identified by glimmer YP_002040567.1 periplasmic protein induced by stress response via Cpx and BaeSR system; similar to CpxP YP_002040568.1 3' incision activity; acts with UvrC YP_002040569.1 catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one; forms homodimers YP_002040570.1 identified by glimmer YP_002040571.1 osmotically-inducible lipoprotein E; activator of ntr-like gene protein YP_002040572.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002040573.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved in N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002040574.1 'catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; involved N,N'-diacetylchitobiose transport; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake' YP_002040575.1 represses the celABCDF-ydjC operon involved in carbon uptake YP_002040576.1 identified by match to protein family HMM PF02056 YP_002040577.1 identified by match to protein family HMM PF04794 YP_002040578.1 Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide YP_002040580.1 identified by match to protein family HMM PF00375 YP_002040581.1 identified by match to protein family HMM PF04307 YP_002040582.1 'YniC; catalyzes the dephosphorylation of 2-deoxyglucose 6-phosphate, mannose 6-phosphate and p-nitrophenyl phosphate' YP_002040584.1 identified by match to protein family HMM PF01636; match to protein family HMM PF03881 YP_002040586.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR03168 YP_002040587.1 identified by match to protein family HMM PF04338 YP_002040589.1 identified by match to protein family HMM PF01223 YP_002040590.1 'catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002040591.1 IF-3 has several functions that are required and promote translation initiation including; preventing association of 70S by binding to 30S; monitoring codon-anticodon interactions by promoting disassociation of fMet-tRNA(fMet) from initiation complexes formed on leaderless mRNAs or incorrectly bound noninitiatior tRNAs and complexes with noncanonical start sites; stimulates codon-anticodon interactions at P-site; involved in moving mRNA to the P-site; and in recycling subunits YP_002040592.1 identified by match to protein family HMM PF01632; match to protein family HMM TIGR00001 YP_002040593.1 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit YP_002040594.1 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily' YP_002040595.1 'catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily' YP_002040596.1 'This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control' YP_002040597.1 with BtuD and BtuF transports vitamin B12 into the cell YP_002040598.1 similar to glutathione peroxidase; member of the btuCED operon which is required for vitamin B12 transport across the inner membrane YP_002040599.1 ATP-binding protein that acts with the transmembrane protein BtuC and the solute binding protein BtuF to transport vitamin B12 into the cell YP_002040600.1 identified by match to protein family HMM PF00877 YP_002040602.1 identified by match to protein family HMM PF02696 YP_002040604.1 tryptophan sensitive; catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate YP_002040605.1 identified by match to protein family HMM PF03618 YP_002040606.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002040607.1 acts in anaerobic beta-oxidation of fatty acids; possible ligase/synthase involved in anaerobic growth on fatty acids YP_002040609.1 identified by match to protein family HMM PF01266; match to protein family HMM PF01494; match to protein family HMM PF03486 YP_002040610.1 May play a role in a redox process YP_002040611.1 'YdiO, YdiQ, YdiR, YdiS, and YdiT may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain' YP_002040612.1 identified by match to protein family HMM PF00165; match to protein family HMM PF07883 YP_002040613.1 may play a role in electron transport between the anaerobic fatty acid oxidation pathway and the respiratory chain YP_002040614.1 identified by match to protein family HMM PF01144 YP_002040615.1 catalyzes the dehydration of 3-dehydroquinate to form 3-dehydroshikimate in aromatic amino acid biosynthesis YP_002040616.1 YdiB; quinate/shikimate dehydrogenase from Escherichia coli uses both NAD and NAD(P) to convert quinate and shikimate to 3-dehydroquinate and 3-dehydroshikimate YP_002040617.1 identified by match to protein family HMM PF07690 YP_002040618.1 identified by match to protein family HMM PF07690 YP_002040619.1 identified by match to protein family HMM PF08965 YP_002040620.1 'YdiK; inner membrane protein; ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated; unknown function' YP_002040621.1 identified by match to protein family HMM PF01565; match to protein family HMM PF02913 YP_002040622.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002040623.1 identified by match to protein family HMM PF00375 YP_002040624.1 functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein YP_002040625.1 with SufCD activates cysteine desulfurase SufS YP_002040626.1 part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE YP_002040627.1 with SufBC activates cysteine desulfurase SufS YP_002040628.1 catalyzes the formation of L-alanine and selenide or sulfanylcysteine from selenocysteine or cysteine YP_002040629.1 Acts with SufS to catalyze the formation of L-alanine from L-cysteine YP_002040630.1 identified by match to protein family HMM PF01476; match to protein family HMM PF03734 YP_002040631.1 identified by match to protein family HMM PF04728 YP_002040632.1 identified by match to protein family HMM PF04728 YP_002040633.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002040634.1 identified by match to protein family HMM PF00324 YP_002040635.1 identified by match to protein family HMM PF07090 YP_002040636.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08220; match to protein family HMM PF08543 YP_002040637.1 identified by match to protein family HMM PF01568; match to protein family HMM PF04879 YP_002040638.1 identified by match to protein family HMM PF03916 YP_002040639.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409 YP_002040640.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002040641.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196; match to protein family HMM PF08281 YP_002040643.1 identified by match to protein family HMM PF04463; match to protein family HMM PF08349 YP_002040644.1 identified by match to protein family HMM PF00376 YP_002040645.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00196 YP_002040646.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002040647.1 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002040648.1 identified by match to protein family HMM TIGR02500 YP_002040649.1 identified by match to protein family HMM TIGR02501 YP_002040650.1 identified by match to protein family HMM PF03433 YP_002040651.1 identified by match to protein family HMM PF07719; match to protein family HMM PF07720; match to protein family HMM TIGR02552 YP_002040652.1 identified by match to protein family HMM PF04888 YP_002040655.1 identified by match to protein family HMM TIGR02552 YP_002040658.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002040659.1 identified by match to protein family HMM TIGR02498 YP_002040660.1 identified by match to protein family HMM PF09525; match to protein family HMM TIGR02497 YP_002040661.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002040663.1 identified by match to protein family HMM TIGR02499 YP_002040664.1 identified by match to protein family HMM PF07018; match to protein family HMM TIGR02511 YP_002040666.1 with SsaC forms part of a protein export system across the inner and outer cell membranes; part of the Salmonella pathogenicity island 2; part of the type III secretion system YP_002040667.1 identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02546 YP_002040670.1 identified by match to protein family HMM PF01052; match to protein family HMM TIGR02551 YP_002040671.1 part of a set of proteins involved in the infection of eukaryotic cells; in plant pathogens involved in the hypersensitivity response YP_002040672.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_002040673.1 'member of a type III secretion system which is part of a pathogenicity island in Salmonella, Yersinia and pathogenic Escherichia coli' YP_002040674.1 NorM; MdtK; functions as a Na(+)/drug antiporter; inactivation in Vibrio cholerae results in susceptibility to fluoroquinolones YP_002040675.1 'catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine' YP_002040676.1 catalyzes the transfer of a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge YP_002040677.1 uncharacterized member of the major facilitator superfamily (MFS) YP_002040678.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040679.1 'binds to the purF operator and coregulates other genes for de novo purine nucleotide synthesis; is involved in regulation of purB, purC, purEK, purHD, purL, purMN and guaBA expression; binds hypoxanthine and guanine as inducers' YP_002040680.1 SodB; iron binding; present under aerobic and anaerobic conditions; destroys free radicals YP_002040681.1 identified by match to protein family HMM PF00877 YP_002040682.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR00365 YP_002040683.1 Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) YP_002040684.1 Ni-dependent; catalyzes the formation of S-lactoylglutathione from methylglyoxal and glutathione YP_002040685.1 FMN-linked; catalyzes the formation of N-ethylsuccinimide from N-ethylmaleimide YP_002040686.1 identified by match to protein family HMM PF00440 YP_002040688.1 identified by match to protein family HMM PF00248 YP_002040689.1 SodC; copper and zinc binding; converts superoxide radicals to hydrogen peroxide and water YP_002040690.1 identified by match to protein family HMM PF04632 YP_002040691.1 identified by match to protein family HMM PF00529 YP_002040692.1 identified by match to protein family HMM PF07869 YP_002040693.1 Transcription regulator that can both activate or repress expression YP_002040694.1 identified by match to protein family HMM PF05433 YP_002040695.1 'catalyzes hydrolysis of 1,6-anhydro bond of anyhydro-N-acetylmuramic acid (anhMurNAc) and phosphorylates anhMurNAc to produce N-acetyl-muramate-6-phosphate; involved in murein recycling' YP_002040696.1 MliC; membrane-bound lysozyme inhibitor of c-type lysozyme YP_002040697.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate YP_002040698.1 catalyzes the formation of tyrosyl-tRNA(Tyr) from tyrosine and tRNA(Tyr) YP_002040699.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002040700.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002040701.1 mutations in this gene confer resistance to the toxic peptide alafosfalin in Salmonella typhimurium; member of proton-dependent oligopeptide transport (POT) system family; in Escherichia coli this gene is regulated by OmpR although not via osmoregulation YP_002040702.1 'DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines' YP_002040703.1 in Excherichia coli RsxABCDEG reduces SoxR which turns off induction of SoxS transcription factor in the absence of oxidizing agents; similar to the rnfABCDGE operon in Rhodobacter capsulatus involved in transferring electrons to nitrogenase YP_002040704.1 part of membrane-bound complex hought to be involved in electron transport to nitrogen YP_002040705.1 RnfD; RsxD; required for nitrogen fixation in Rhodobacter capsulatus; part of a membrane-bound complex thought to be involved in electron transport to nitrogenase; in Escherichia coli this gene is part of a cluster controlling SoxR-mediated induction of the SoxS transcription factor in the absence of oxidizing agents YP_002040706.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002040707.1 part of membrane-bound complex thought to be involved in electron transport to nitrogen YP_002040708.1 identified by match to protein family HMM PF02508; match to protein family HMM TIGR01943 YP_002040710.1 'YdgT; in E. coli, when complexed with H-NS or StpA binds a 26 base-pair DNA sequence of oriC; seems to play a role in optimizing the activity of oriC; non-essential; Hha protein paralog; in an hha mutant background, cnu is overexpressed and can compensate hha-induced phenotypes' YP_002040711.1 identified by match to protein family HMM PF01118; match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002040712.1 catalyzes the formation of inosine from adenosine YP_002040713.1 identified by match to protein family HMM PF06097 YP_002040714.1 identified by match to protein family HMM PF01238; match to protein family HMM TIGR00218 YP_002040715.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002040716.1 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle YP_002040717.1 binds to DNA replication terminator sequences to prevent passage of replication forks YP_002040718.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002040719.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969 YP_002040720.1 identified by match to protein family HMM PF00267 YP_002040722.1 response regulator in two-component regulatory system with RstB YP_002040723.1 identified by match to protein family HMM PF06942 YP_002040724.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR00905 YP_002040725.1 identified by match to protein family HMM PF07338 YP_002040726.1 forms a tetramer composed of 2 alpha subunits and 2 beta subunits in the inner membrane; involved in catalyzing transfer of hydride ion equivalents between NAD and NADP; stereospecific (AB-specific); functions as a proton pump by translocating protons from cytoplasm to periplasm YP_002040727.1 catalyzes reversible transfer of hydride ion equivalent between NAD and NADP; membrane-bound proton pump that translocates protons from cytosolic to periplasmic side of the inner membrane; forms a tetramer composed of two alpha and 2 beta subunits; AB-stereospecific enzyme YP_002040728.1 transport of quorum-sensing signal; mutations in this gene alters the transport of the quorum-sensing signal autoinducer 2 (AI-2) which affects expression of a large number of genes YP_002040730.1 'with MdtI is involved in resistance to deoxycholate , nalidixic acid, fosfomycin, and SDS' YP_002040731.1 'with MdtJ is involved in resistance to deoxycholate, nalidixic acid, fosfomycin, and SDS' YP_002040732.1 identified by match to protein family HMM PF00089 YP_002040733.1 identified by glimmer YP_002040734.1 required for growth and survival under moderately acid conditions YP_002040735.1 identified by match to protein family HMM PF07690 YP_002040736.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040737.1 identified by match to protein family HMM PF00480 YP_002040738.1 'DTB synthetase; dethiobiotin synthase; involved in production of dethiobiotin from ATP and 7,8-diaminononanoate and carbon dioxide; contains magnesium' YP_002040739.1 identified by match to protein family HMM PF00654 YP_002040740.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00571; match to protein family HMM TIGR01186 YP_002040741.1 identified by match to protein family HMM PF00528 YP_002040742.1 identified by match to protein family HMM PF04069 YP_002040743.1 identified by match to protein family HMM PF00528 YP_002040744.1 'binds to the twin-arginine signal peptides of certain proteins, including dimethylsulfoxide reductase and trimethylamine N-oxide reductase that are translocated to the cytoplasmic membrane' YP_002040745.1 identified by match to protein family HMM PF04976 YP_002040746.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002040747.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002040748.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002040749.1 identified by match to protein family HMM PF06649 YP_002040750.1 identified by match to protein family HMM PF06788 YP_002040751.1 identified by match to protein family HMM PF00583 YP_002040752.1 identified by match to protein family HMM PF06932 YP_002040753.1 identified by match to protein family HMM PF02694 YP_002040754.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002040755.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002040756.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002040758.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002040759.1 identified by match to protein family HMM TIGR03318 YP_002040760.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002040761.1 'NADP(+)-dependent; catalyzes the formation of 2-aminomalonate-semialdehyde from L-serine; can also use 3-hydroxybutyrate, 3-hydroxy-isobutyrate, D-threonine, L-allo-threonine,D-serine' YP_002040762.1 identified by match to protein family HMM PF01432 YP_002040764.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002040765.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002040767.1 YdeF; uncharacterized member of the major facilitator superfamily (MFS) of transporters YP_002040768.1 identified by match to protein family HMM PF00892 YP_002040770.1 'transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype; also activates sodA, zwf and micF' YP_002040771.1 Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes YP_002040772.1 'protein involved in resistance to different drugs (tetracycline, chloramphenicol, beta-lactams, and quinolones); part of the multiple antibiotic resistance (mar) locus, which is composed by the genes marC and marRAB; unknown function' YP_002040773.1 identified by match to protein family HMM PF07690 YP_002040774.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040775.1 in Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase YP_002040776.1 catalyzes the formation of glutamate from glutamine YP_002040779.1 identified by match to protein family HMM PF00267 YP_002040780.1 identified by match to protein family HMM PF01155; match to protein family HMM TIGR00100 YP_002040782.1 identified by match to protein family HMM PF00301; match to protein family HMM PF04809 YP_002040783.1 identified by match to protein family HMM PF07449 YP_002040784.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_002040785.1 identified by match to protein family HMM PF01750; match to protein family HMM TIGR00072; match to protein family HMM TIGR00140 YP_002040786.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_002040787.1 identified by match to protein family HMM PF00374 YP_002040788.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391 YP_002040789.1 identified by match to protein family HMM PF02275 YP_002040790.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002040791.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002040792.1 identified by match to protein family HMM PF07690 YP_002040794.1 identified by match to protein family HMM PF07690 YP_002040795.1 identified by match to protein family HMM PF01494 YP_002040796.1 identified by match to protein family HMM PF01047 YP_002040799.1 identified by match to protein family HMM PF07377 YP_002040801.1 identified by glimmer YP_002040803.1 identified by match to protein family HMM PF00532 YP_002040804.1 identified by match to protein family HMM PF03553; match to protein family HMM TIGR00931 YP_002040805.1 identified by match to protein family HMM PF00155 YP_002040806.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02100 YP_002040807.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02401 YP_002040808.1 identified by match to protein family HMM PF00128; match to protein family HMM PF02922; match to protein family HMM TIGR02402 YP_002040809.1 identified by match to protein family HMM PF06884 YP_002040811.1 identified by match to protein family HMM PF02566; match to protein family HMM TIGR03562 YP_002040813.1 identified by glimmer YP_002040814.1 malic enzyme; oxaloacetate-decarboxylating; NAD-dependent; catalyzes the formation of pyruvate form malate YP_002040815.1 similar to zinc-dependent eukaryotic ADH enzymes and distinct from fermentative ADHs YP_002040816.1 'nitrate-inducible, cytochrome b556(fdn) component of formate dehydrogenase' YP_002040817.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002040818.1 identified by match to protein family HMM PF00892 YP_002040819.1 identified by match to protein family HMM PF00267 YP_002040820.1 identified by match to protein family HMM PF04828 YP_002040821.1 identified by match to protein family HMM PF07690 YP_002040822.1 identified by match to protein family HMM PF00440 YP_002040823.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002040824.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002040825.1 identified by match to protein family HMM TIGR01660 YP_002040826.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002040827.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002040828.1 identified by match to protein family HMM PF02567; match to protein family HMM TIGR00654 YP_002040829.1 identified by match to protein family HMM PF00797 YP_002040831.1 identified by match to protein family HMM PF00324 YP_002040832.1 identified by match to protein family HMM PF06004 YP_002040834.1 identified by match to protein family HMM PF00593; match to protein family HMM PF07715 YP_002040835.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002040836.1 identified by match to protein family HMM PF00107 YP_002040837.1 identified by match to protein family HMM PF00583 YP_002040838.1 identified by match to protein family HMM PF04657 YP_002040841.1 identified by match to protein family HMM PF07520 YP_002040844.1 catalyzes the formation of 4-aminobutanoate from 4-aminobutanal; involved in putrescine degradation YP_002040845.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002040846.1 identified by match to protein family HMM PF01427 YP_002040848.1 translocated by the type III secretion system SPI-2; localizes to Sifs in infected cells and specifically to Salmonella-containing vacuoles YP_002040850.1 identified by match to protein family HMM PF01136 YP_002040851.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002040852.1 identified by match to protein family HMM PF00860; match to protein family HMM PF03594; match to protein family HMM TIGR00843 YP_002040854.1 with TehA confers resistance to tellurite YP_002040855.1 identified by match to protein family HMM PF03595; match to protein family HMM TIGR00816 YP_002040857.1 identified by match to protein family HMM PF00583 YP_002040858.1 identified by match to protein family HMM PF01546; match to protein family HMM PF05343 YP_002040859.1 identified by match to protein family HMM PF02302 YP_002040860.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_002040861.1 identified by match to protein family HMM PF03437; match to protein family HMM TIGR00259 YP_002040862.1 identified by match to protein family HMM PF00359 YP_002040863.1 identified by match to protein family HMM PF00834 YP_002040864.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002040865.1 identified by match to protein family HMM PF00583 YP_002040866.1 identified by match to protein family HMM PF01070; match to protein family HMM PF01180 YP_002040867.1 identified by match to protein family HMM PF04264 YP_002040868.1 involved in the control of the structural glucose backbone of osmoregulated periplasmic glucans YP_002040869.1 identified by match to protein family HMM PF00135 YP_002040870.1 identified by match to protein family HMM PF07063 YP_002040871.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040872.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002040873.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02818 YP_002040874.1 identified by match to protein family HMM PF02583 YP_002040875.1 identified by glimmer YP_002040876.1 identified by glimmer YP_002040878.1 identified by glimmer YP_002040880.1 identified by match to protein family HMM PF06961 YP_002040881.1 identified by match to protein family HMM PF00497 YP_002040883.1 identified by match to protein family HMM PF00005 YP_002040884.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002040886.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002040887.1 B-type di-heme cytochrome with a major alpha-absorption peak at 561 nm and a minor peak at 555 nm YP_002040888.1 identified by match to protein family HMM PF02698 YP_002040889.1 'involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain' YP_002040890.1 FMN-dependent; requires NADH; catalyzes the cleavage of azo bond in aromatic azo compounds YP_002040891.1 identified by match to protein family HMM PF04828 YP_002040892.1 identified by match to protein family HMM PF07027 YP_002040895.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002040896.1 identified by match to protein family HMM PF03724 YP_002040899.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01558; match to protein family HMM PF01855; match to protein family HMM TIGR02176 YP_002040900.1 identified by match to protein family HMM PF00582 YP_002040901.1 identified by match to protein family HMM PF00893 YP_002040902.1 identified by glimmer YP_002040903.1 TtcA; YdaO; catalyzes the thiolation of cytosine 32 in specific tRNAs YP_002040904.1 'exhibits an RNA-dependent ATPase activity, specifically stimulated by bacterial 23S rRNA' YP_002040905.1 identified by match to protein family HMM PF01544 YP_002040906.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002040908.1 identified by glimmer YP_002040909.1 identified by match to protein family HMM PF01713 YP_002040910.1 identified by match to protein family HMM PF01035; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002040911.1 Global transcription factor that controls the expression of over 100 target genes in response to anoxia YP_002040912.1 with UspC and UspD is involved in resistance to UV irradiation YP_002040914.1 identified by match to protein family HMM PF00924 YP_002040915.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002040916.1 identified by match to protein family HMM PF03483 YP_002040922.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002040924.2 identified by match to protein family HMM PF06004 YP_002040925.1 identified by match to protein family HMM PF00440 YP_002040926.1 identified by match to protein family HMM PF00106 YP_002040927.1 identified by match to protein family HMM PF00248 YP_002040928.1 identified by glimmer YP_002040929.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002040930.1 identified by match to protein family HMM PF05368 YP_002040931.1 identified by match to protein family HMM PF00496 YP_002040932.1 identified by match to protein family HMM PF00246 YP_002040933.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002040934.1 antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein YP_002040935.1 regulates genes involved in the biosynthesis and transport of aromatic amino acids YP_002040936.1 identified by match to protein family HMM PF05128; match to protein family HMM TIGR01620 YP_002040937.1 identified by match to protein family HMM PF04317 YP_002040938.1 rhodanese; catalyzes the formation of thiocyanate from thiosulfate and hydrogen cyanide YP_002040939.1 identified by match to protein family HMM PF09584; match to protein family HMM TIGR02979 YP_002040940.1 'with PsbB forms toxin/antitoxin pair; activates the psp operon in response to phage infection, exposure to ethanol or osmotic shock' YP_002040941.1 'acts together with PspC to induce psp operon during infection with phage, exposure to ethanol or osmotic shock; forms a complex with PspA and C; PspC is required for PspAB binding' YP_002040942.1 involved in maintaining membrane potential under membrane stress conditions; also acts as a negative transcriptional regulator of the phage shock protein (psp) operon(pspABCDE) by regulating the transcriptional activator PspF YP_002040943.1 'transcriptional activator for pspABCE which are induced in response to phage proteins, membrane altering stresses, and impaired proton expor' YP_002040944.1 identified by match to protein family HMM PF00496 YP_002040945.1 identified by match to protein family HMM PF00528 YP_002040946.1 identified by match to protein family HMM PF00528 YP_002040947.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002040948.1 identified by match to protein family HMM PF00005 YP_002040951.1 Catalyzes a key regulatory step in fatty acid biosynthesis YP_002040952.1 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction YP_002040953.1 c-di-GMP phosphodiesterase; probably degrades signalling molecule c-di-GMP YP_002040955.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002040957.1 involved in start site selection during the initiation of translation YP_002040958.1 identified by match to protein family HMM PF00215; match to protein family HMM TIGR01740 YP_002040959.1 identified by match to protein family HMM PF07719 YP_002040960.1 identified by match to protein family HMM PF06305 YP_002040961.1 identified by match to protein family HMM PF01569 YP_002040962.2 'catalyzes the conversion of GTP to formate and 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate' YP_002040963.1 Catalyzes the conversion of citrate to isocitrate YP_002040966.1 LysR-type transcriptional regulator; contains helix-turn-helix (HTH) motif; in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon; autoregulates expression; crystal structure of Klebsiella aerogenes showed tetramer formation YP_002040967.1 identified by glimmer YP_002040968.1 'catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining, maintains net negative superhelicity' YP_002040970.1 SohB; periplasmic protein; member of the peptidase S49 family YP_002040971.1 identified by match to protein family HMM PF00106; match to protein family HMM PF08659 YP_002040972.1 'catalyzes the formation of adenosylcob(III)yrinic acid a,c-diamide from cob(I)yrinic acid a,c-diamide' YP_002040973.1 catalyzes the synthesis of pseudouridine from uracil-2605 in 23S ribosomal RNA YP_002040974.1 identified by match to protein family HMM PF01300; match to protein family HMM TIGR00057 YP_002040975.1 identified by match to protein family HMM PF02811 YP_002040976.1 'with component II, the glutamine amidotransferase, catalyzes the formation of anthranilate from chorismate and glutamine' YP_002040977.1 bifunctional anthranilate synthase II/anthranilate phosphoribosyltransferase; TrpD; forms a heterotetramer with Trp E and the complex catalyzes the formation of anthranilate from chorismate and glutamine; also catalyzes the formation of N-(5-phospho-D-ribosyl)-anthranilate from athranilate and 5-phospho-alpha-D-ribose 1-diphosphate; functions in tryptophan biosynthesis YP_002040978.1 monomeric bifunctional protein; functions in tryptophan biosynthesis pathway; phosphoribosylanthranilate is rearranged to carboxyphenylaminodeoxyribulosephosphate which is then closed to form indole-3-glycerol phosphate YP_002040979.1 catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate YP_002040980.1 catalyzes the formation of indole and glyceraldehyde 3-phosphate from indoleglycerol phosphate in tryptophan biosynthesis YP_002040982.1 identified by match to protein family HMM PF05974 YP_002040983.1 identified by match to protein family HMM PF05974 YP_002040984.1 identified by match to protein family HMM PF05067 YP_002040985.1 receptor for colicin S4 YP_002040986.1 identified by match to protein family HMM PF03692 YP_002040987.1 identified by match to protein family HMM PF06790 YP_002040988.1 Involved in cell division; probably involved in intracellular septation YP_002040989.1 YciA; hydrolase that catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA; member of the the acyl coenzyme A hydrolase family of proteins YP_002040990.1 'membrane spanning protein in TonB-ExbB-ExbD complex; transduces proton motive force of the cytoplasmic membrane to outer membrane transporters; involved in the transport of ron-siderophore complexes, vitamin B12 and colicins' YP_002040991.1 'unknown function; YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity' YP_002040993.1 catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) YP_002040994.1 identified by match to protein family HMM PF00520; match to protein family HMM PF07885 YP_002040995.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002040996.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352; match to protein family HMM TIGR01727 YP_002040997.1 identified by match to protein family HMM PF00528 YP_002040998.1 identified by match to protein family HMM PF00528 YP_002040999.1 identified by match to protein family HMM PF00496 YP_002041000.1 identified by match to protein family HMM PF01914; match to protein family HMM TIGR00427 YP_002041001.1 identified by match to protein family HMM PF00171; match to protein family HMM PF00465 YP_002041002.1 catalyzes the formation of thymidine 5'-phosphate from thymidine YP_002041003.1 identified by match to protein family HMM PF00816 YP_002041004.1 'together with GalF subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose' YP_002041005.1 identified by match to protein family HMM PF00072 YP_002041006.1 identified by match to protein family HMM PF01734 YP_002041007.1 identified by match to protein family HMM PF02810 YP_002041008.1 produces formate from formyl-tetrahydrofolate which is the major source of formate for PurT in de novo purine nucleotide biosynthesis; has a role in one-carbon metabolism; forms a homohexamer; activated by methionine and inhibited by glycine YP_002041009.1 identified by match to protein family HMM PF08238 YP_002041011.1 identified by match to protein family HMM PF02665; match to protein family HMM TIGR00351 YP_002041012.1 identified by match to protein family HMM PF02613; match to protein family HMM TIGR00684 YP_002041013.1 identified by match to protein family HMM TIGR01660 YP_002041014.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR01580 YP_002041015.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00886 YP_002041016.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002041017.1 two-component response regulator NarL; phosphorylated by NarQ; activates transcription of nitrate and nitrite reductase genes and represses transcription of fumarate reductase YP_002041019.1 identified by match to protein family HMM PF02635 YP_002041020.1 in Escherichia coli this protein ly regulates the sodium/proton (also pH-independent calcium/proton) antiporter chaA; has weak affinity for calcium and magnesium ions YP_002041021.1 identified by match to protein family HMM PF01699; match to protein family HMM TIGR00846 YP_002041022.1 catalyzes the formation of 2-dehydro-3-deoxy-D-octonate 8-phosphate from phosphoenolpyruvate and D-arabinose 5-phosphate in LPS biosynthesis YP_002041024.1 identified by match to protein family HMM PF04247 YP_002041025.1 HemK; PrmC; transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB YP_002041026.1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2 YP_002041027.1 catalyzes the formation of glutamate-1-semialdehyde from glutamyl-tRNA(Glu) and NADPH; the second step of the pathway is catalyzed by glutamate-1-semialdehyde aminomutase which results in the formation of 5-aminolevulinic acid; functions in porphyrin (tetrapyrroles) biosynthesis; the crystal structure showed a C-terminal dimerization domain that appears to be absent in Chlamydial proteins YP_002041028.1 identified by glimmer YP_002041029.1 Incorporates lipoproteins in the outer membrane after they are released by the LolA protein YP_002041030.1 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis YP_002041031.1 identified by glimmer YP_002041032.1 catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP YP_002041033.1 role in sulfate transport across the inner membrane; member of the SulP family of sulfate transporters; seems to mediate transport via sulfate/proton symport YP_002041034.1 'YchH; transcription activated by CRP (cyclic AMP receptor protein), a global transcription factor involved in regulation of metabolism in enteric bacteria; ychH presents a class II promoter to bind CRP; unknown function' YP_002041035.1 Enables the recycling of peptidyl-tRNAs produced at termination of translation YP_002041036.1 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1 YP_002041037.1 identified by glimmer YP_002041038.1 identified by glimmer YP_002041039.1 identified by glimmer YP_002041042.1 identified by glimmer YP_002041043.1 identified by match to protein family HMM PF01058; match to protein family HMM PF08425; match to protein family HMM TIGR00391; match to protein family HMM TIGR01409 YP_002041044.1 involved in hydrogen cycling during fermentative growth YP_002041045.1 identified by match to protein family HMM PF01292; match to protein family HMM TIGR02125 YP_002041046.1 HyaD; endopeptidase involved in the cleavage of the C-terminus end of HyaB (the large subunit of hydrogenase 1) YP_002041047.1 involved in processing hydrogenase proteins HyaA and HyaB YP_002041048.1 identified by match to protein family HMM PF04809 YP_002041049.1 identified by match to protein family HMM PF01654 YP_002041050.1 identified by match to protein family HMM PF02322; match to protein family HMM TIGR00203 YP_002041051.1 identified by match to protein family HMM PF00208; match to protein family HMM PF02812 YP_002041052.1 identified by glimmer YP_002041053.1 periplasmic; catalyzes the hydrolysis of trehalose to glucose which can then be imported into the cell YP_002041054.1 identified by match to protein family HMM PF04226 YP_002041055.1 identified by match to protein family HMM PF07238; match to protein family HMM PF07317 YP_002041056.1 catalyzes the release of D-alanine from L-alanyl-D-glutamyl-meso-diaminopimelyl-D-alanine YP_002041057.1 the Vibrio parahaemolyticus gene VP2867 was found to be a potassium/proton antiporter; can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli YP_002041058.1 'catabolic enzyme, converts L-alanine to D-alanine which is then oxidized to pyruvate by dadA' YP_002041059.1 catalyzes the oxidative deamination of D-amino acids YP_002041060.1 identified by match to protein family HMM PF04293 YP_002041061.1 Multifunctional regulator of fatty acid metabolism YP_002041062.1 involved in regulation of intracellular pH under alkaline conditions YP_002041063.1 disulfide oxidoreductase; integral membrane protein; required for perioplasmic disulfide bond formation; oxidizes DsbA protein YP_002041064.1 identified by match to protein family HMM PF09313 YP_002041065.1 identified by match to protein family HMM PF08178 YP_002041066.1 identified by glimmer YP_002041068.1 identified by match to protein family HMM PF03692 YP_002041069.1 identified by match to protein family HMM PF01557 YP_002041071.1 blocks the formation of polar Z-ring septums YP_002041072.1 ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums YP_002041073.1 works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell YP_002041074.1 identified by match to protein family HMM PF00570; match to protein family HMM PF01612; match to protein family HMM TIGR01388 YP_002041075.1 Activates fatty acids by binding to coenzyme A YP_002041076.1 identified by match to protein family HMM PF03843; match to protein family HMM TIGR00752 YP_002041077.1 identified by match to protein family HMM PF00814 YP_002041079.1 identified by match to protein family HMM PF01042 YP_002041080.1 identified by match to protein family HMM PF03701 YP_002041081.1 identified by match to protein family HMM PF00425; match to protein family HMM PF04715; match to protein family HMM TIGR00553 YP_002041082.1 identified by match to protein family HMM PF00293 YP_002041083.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002041084.1 identified by match to protein family HMM PF00563 YP_002041085.1 identified by match to protein family HMM PF00571; match to protein family HMM PF03471; match to protein family HMM PF03741 YP_002041086.1 identified by match to protein family HMM PF03610; match to protein family HMM PF03830; match to protein family HMM TIGR00824; match to protein family HMM TIGR00854 YP_002041087.1 identified by match to protein family HMM PF03609; match to protein family HMM TIGR00822 YP_002041088.1 hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IID with IIC forms the translocation channel YP_002041089.1 identified by match to protein family HMM PF06173 YP_002041090.1 identified by match to protein family HMM PF02659 YP_002041091.1 methylates the guanosine in position 745 of 23S rRNA; required for translation and cell growth YP_002041092.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717 YP_002041093.1 identified by match to protein family HMM PF00313 YP_002041097.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002041098.1 metalloprotease YP_002041099.1 Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 YP_002041100.1 affects solute and DNA transport through an unknown mechanism YP_002041101.2 identified by match to protein family HMM PF01590 YP_002041102.1 identified by match to protein family HMM PF04403; match to protein family HMM TIGR00155 YP_002041103.1 identified by match to protein family HMM PF02470 YP_002041104.1 in Escherichia coli this enzyme specifically methylates C1407 of the 16S rRNA YP_002041105.1 identified by match to protein family HMM PF07351 YP_002041106.1 identified by match to protein family HMM PF07358 YP_002041107.1 Plays a key role in signaling protein misfolding via the cpxR/cpxA transducing system; modulates the phosphorylated status of many phosphoproteins YP_002041108.1 identified by glimmer YP_002041111.1 identified by match to protein family HMM PF05364; match to protein family HMM PF07487 YP_002041112.1 identified by glimmer YP_002041113.1 identified by match to protein family HMM PF07166 YP_002041115.1 identified by glimmer YP_002041116.1 identified by glimmer YP_002041117.1 identified by glimmer YP_002041118.1 identified by glimmer YP_002041119.1 identified by glimmer YP_002041120.1 identified by match to protein family HMM PF01757 YP_002041121.1 identified by glimmer YP_002041122.1 identified by glimmer YP_002041126.1 identified by glimmer YP_002041127.1 identified by match to protein family HMM PF00892 YP_002041132.1 identified by match to protein family HMM PF01661; match to protein family HMM PF02413 YP_002041133.1 identified by match to protein family HMM PF07278 YP_002041134.1 identified by glimmer YP_002041137.1 identified by match to protein family HMM PF00589; match to protein family HMM PF09003 YP_002041139.1 identified by match to protein family HMM PF05425 YP_002041140.1 identified by match to protein family HMM PF04234 YP_002041141.1 identified by match to protein family HMM PF06440 YP_002041142.1 identified by match to protein family HMM PF00795 YP_002041143.1 3'-5' exonuclease activity on single or double-strand DNA YP_002041144.1 PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues YP_002041145.1 identified by match to protein family HMM PF04391 YP_002041146.1 secreted protein; unknown function YP_002041147.1 identified by match to protein family HMM PF07130 YP_002041148.1 'non-folate utilizing enzyme, catalyzes the production of beta-formyl glycinamide ribonucleotide from formate, ATP, and beta-GAR and a side reaction producing acetyl phosphate and ADP from acetate and ATP; involved in de novo purine biosynthesis' YP_002041149.1 catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate YP_002041150.1 catalyzes the formation of 2-dehydro-3-deoxy-6-phospho-D-gluconate from 6-phospho-D-gluconate YP_002041151.1 'catalyzes the formation of D-glucono-1,5-lactone 6-phosphate from D-glucose 6-phosphate' YP_002041152.1 'Represses the expression of the zwf, eda, glp and gap' YP_002041153.1 catalyzes the formation of phosphoenolpyruvate from pyruvate YP_002041154.1 'Transfers myristate or laurate, activated on ACP, to the lipid IVA moiety of (KDO)2-(lauroyl)-lipid IVA' YP_002041155.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551; match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002041156.1 involved in transport of zinc(II) with ZnuA and C YP_002041157.1 involved in transport of zinc(II) with ZnuA and C YP_002041158.1 involved in transport of zinc(II) with ZnuA and C YP_002041159.1 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration YP_002041160.1 plays an essential role in ATP-dependent branch migration of the Holliday junction YP_002041162.1 identified by match to protein family HMM PF06520 YP_002041163.1 endonuclease; resolves Holliday structures; forms a complex of RuvABC; the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration; RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity YP_002041164.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002041165.1 converts dATP to dAMP and pyrophosphate YP_002041166.1 'catalyzes a two-step reaction, first charging an aspartate molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; contains discriminating and non-discriminating subtypes' YP_002041167.1 identified by match to protein family HMM PF00857 YP_002041168.1 identified by match to protein family HMM PF01904 YP_002041170.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242; match to protein family HMM TIGR00740 YP_002041171.1 identified by match to protein family HMM PF08003; match to protein family HMM PF08241; match to protein family HMM TIGR00452 YP_002041172.1 identified by match to protein family HMM PF03932 YP_002041173.1 identified by match to protein family HMM PF06185 YP_002041174.1 identified by glimmer YP_002041175.1 'catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase' YP_002041176.1 identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423 YP_002041177.1 identified by match to protein family HMM PF07470 YP_002041178.1 identified by match to protein family HMM PF06366 YP_002041179.1 membrane protein involved in the flagellar export apparatus YP_002041180.1 membrane protein responsible for substrate specificity switching from rod/hook-type export to filament-type export YP_002041181.1 cytosolic phosphatase which functions in the chemotaxis signal transduction complex by controlling the level of phosphorylated CheY through dephosphorylation YP_002041182.1 'chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble' YP_002041183.1 regulates chemotaxis by demethylation of methyl-accepting chemotaxis proteins YP_002041184.1 methylates the MCP YP_002041185.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002041187.1 identified by match to protein family HMM PF01584 YP_002041188.1 chemotactic sensory histidine kinase in two-component regulatory system with CheB and CheY; sensory histidine kinase/signal sensing protein; CheA is the histidine kinase component YP_002041189.1 with MotA forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002041190.1 With MotB forms the ion channels that couple flagellar rotation to proton/sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine YP_002041191.1 With FlhD is involved in the activation of class 2 flagellar genes and as well as a number of other genetic systems YP_002041192.1 with FlhC is involved in the activation of class 2 flagellar genes and is involved in the regulation of a number of other genetic systems YP_002041193.1 identified by glimmer YP_002041194.1 'ppGpp-dependent; membrane-associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress' YP_002041195.1 identified by match to protein family HMM PF00982; match to protein family HMM TIGR02400 YP_002041196.1 biosynthetic; catalyzes the formation of trehalose and phosphate from trehalose-6-phosphate; expression is increased under osmotic stress and induced during the transition to stationary phase and by decreased temperature YP_002041197.1 identified by match to protein family HMM PF01965 YP_002041198.1 identified by glimmer YP_002041199.1 identified by match to protein family HMM PF00210 YP_002041200.1 identified by match to protein family HMM PF02502 YP_002041203.1 cytoplasmic iron storage protein YP_002041205.1 identified by match to protein family HMM PF01490; match to protein family HMM PF03222; match to protein family HMM TIGR00837 YP_002041206.1 identified by match to protein family HMM PF02810; match to protein family HMM TIGR02292 YP_002041208.1 identified by match to protein family HMM PF00877 YP_002041210.1 identified by glimmer YP_002041211.1 identified by match to protein family HMM PF01066; match to protein family HMM TIGR00560 YP_002041212.1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision YP_002041213.1 in Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system; in Salmonella SirA and BarA regulate virulence gene expression also via the Csr system YP_002041215.1 regulates genes involved in cell division YP_002041216.1 identified by match to protein family HMM PF00005 YP_002041217.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002041218.1 catalyzes the formation of pyruvate from D-cysteine YP_002041219.1 identified by match to protein family HMM PF00497 YP_002041220.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor directs late flagellar biosynthesis genes YP_002041222.1 'structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes' YP_002041223.1 identified by glimmer YP_002041224.1 involved in flagellin assembly YP_002041225.1 flagellin specific chaperone YP_002041226.1 binds flagellar cap subunits (FliD) and seems to prevents their oligomerization prior to its translocation through the flagellum-specific type III export pathway; acts as a repressor of flagellar class 2 operons by preventing FlhD2C2 to bind the promoter and inhibiting the FlhD2C2-dependent transcription; member of the type III cytoplasmic chaperone family YP_002041227.1 'converts 1,4-alpha-D-glucans to maltodextrin' YP_002041229.2 identified by match to protein family HMM PF04143 YP_002041230.1 identified by match to protein family HMM PF01206 YP_002041232.1 forms a junction between the M-ring and FlgB during flagella biosynthesis YP_002041234.1 'the MS-ring anchors the flagellum to the cytoplasmic membrane; part of the flagellar basal body which consists of four rings L, P, S, and M mounted on a central rod' YP_002041235.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002041236.1 binds to and inhibits the function of flagella specific ATPase FliI YP_002041237.1 involved in type III protein export during flagellum assembly YP_002041238.1 rod/hook and filament chaperone YP_002041239.1 identified by match to protein family HMM PF02120 YP_002041240.1 interacts with cytoplasmic MS ring of the basal body and may act to stabilize the MotAB complexes which surround the MS ring YP_002041241.1 with FliG and FliN makes up the switch complex which is involved in switching the direction of the flagella rotation YP_002041242.1 One of three proteins involved in switching the direction of the flagellar rotation YP_002041243.1 'with FlhA, FlhB, FliP, FliQ and FliR is one of the membrane components of the flagellar export apparatus' YP_002041244.1 'FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus' YP_002041245.1 with proteins FliP and FliR forms the core of the central channel in the flagella export apparatus YP_002041246.1 'FliR, with proteins FliP and FliQ, forms the core of the central channel in the flagella export apparatus' YP_002041247.1 identified by match to protein family HMM PF00196 YP_002041250.1 catalyzes the hydrolysis of mannosyl-3-phosphoglycerate to form the osmolyte mannosylglycerate YP_002041251.1 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002041253.1 identified by match to protein family HMM PF05661 YP_002041254.1 identified by match to protein family HMM PF00892 YP_002041255.1 identified by match to protein family HMM PF03852; match to protein family HMM TIGR00632 YP_002041256.1 identified by match to protein family HMM PF00145; match to protein family HMM TIGR00675 YP_002041257.1 identified by match to protein family HMM PF01966 YP_002041259.1 identified by glimmer YP_002041260.1 identified by match to protein family HMM PF00267 YP_002041262.1 binds processed UmuD protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002041263.1 binds with UmuC protein to form functional DNA pol V (UmuD'2UmuC); involved in translesion polymerization YP_002041265.1 identified by match to protein family HMM PF06167 YP_002041269.1 identified by match to protein family HMM PF07661; match to protein family HMM PF08238 YP_002041273.1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile YP_002041274.1 identified by glimmer YP_002041277.1 identified by match to protein family HMM PF01758; match to protein family HMM TIGR00832 YP_002041278.1 identified by match to protein family HMM PF02374; match to protein family HMM TIGR00345 YP_002041279.1 identified by match to protein family HMM PF06953 YP_002041280.1 identified by match to protein family HMM PF01451 YP_002041282.1 identified by match to protein family HMM PF03734 YP_002041283.1 'catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide and 5,6-dimethylbenzimidazole' YP_002041284.1 catalyzes the formation of adenosylcobalamin from Ado-cobinamide-GDP and alpha-ribazole YP_002041285.1 catalyzes ATP-dependent phosphorylation of adenosylcobinamide to form adenosylcobinamide phosphate and the addition of guanosine monophosphate to adenosylcobinamide phosphate to form adenosylcobinamide-GDP YP_002041286.1 'catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation' YP_002041287.1 with CbiNQ forms the ABC transporter for cobalt import YP_002041288.1 identified by match to protein family HMM PF02361; match to protein family HMM TIGR02454 YP_002041289.1 periplasmic cobalt binding component of the cobalt transport system YP_002041290.1 catalyzes the ATP-dependent transport of cobalt YP_002041291.1 catalyzes the formation of precorrin-3A from precorrin-2 YP_002041292.1 identified by match to protein family HMM PF06180 YP_002041293.1 'CobK/CbiJ; there are 2 pathways for cobalamin (vitamin B12) production, one aerobic (ex. P. denitrificans), the other anaerobic (ex. S. typhimurium); the CobK/CbiJ perform similar reactions in both; the anaerobic pathway includes the use of a chelated cobalt ion in order for ring contraction to occur; CobK thus converts precorrin 6 into dihydro-precorrin 6 while CbiJ converts cobalt-precorrin 6 into cobalt-deihydro-precorrin 6' YP_002041294.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01466 YP_002041295.1 catalyzes the formation of cobalt-precorrin 4 from cobalt-precorrin 3 YP_002041296.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR01465 YP_002041297.1 catalyzes the methylation of either C-15 or C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W; decarboxylating YP_002041298.1 catalyzes the methylation of C-5 in cobalt-precorrin-6Y to form cobalt-precorrin-7W-a YP_002041299.1 Catalyzes the methylation of C-1 in cobalt-precorrin-5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A YP_002041300.1 catalyzes the interconversion of cobalt-precorrin-8X and cobyrinic acid in the anaerobic biosynthesis of cobalamin YP_002041301.1 CobD; CbiB in Salmonella; converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group YP_002041302.1 responsible for the amidation of carboxylic groups at position A and C of cobyrinic acid or hydrogenobrynic acid YP_002041303.1 identified by match to protein family HMM PF00165 YP_002041304.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002041305.1 identified by match to protein family HMM PF00936 YP_002041306.1 identified by match to protein family HMM PF00936 YP_002041307.1 identified by match to protein family HMM PF02286 YP_002041308.1 identified by match to protein family HMM PF02288 YP_002041309.1 identified by match to protein family HMM PF02287 YP_002041310.1 identified by match to protein family HMM PF08841 YP_002041312.1 identified by match to protein family HMM PF00936 YP_002041313.1 identified by match to protein family HMM PF00936 YP_002041314.1 identified by match to protein family HMM PF06130 YP_002041316.1 identified by match to protein family HMM PF03319 YP_002041317.1 identified by match to protein family HMM PF01923; match to protein family HMM PF03928; match to protein family HMM TIGR00636 YP_002041318.1 identified by match to protein family HMM PF00171 YP_002041319.1 identified by match to protein family HMM PF00465 YP_002041320.1 identified by match to protein family HMM PF01512 YP_002041321.1 identified by match to protein family HMM PF00936 YP_002041322.1 identified by match to protein family HMM PF00936 YP_002041323.1 identified by match to protein family HMM TIGR02528 YP_002041324.1 'involved in coenzyme B(12)-dependent 1, 2-propanediol degradation; important for the synthesis of propionyl coenzyme A during growth on 1,2-propanediol' YP_002041325.1 identified by match to protein family HMM PF00288; match to protein family HMM PF08544 YP_002041326.1 identified by match to protein family HMM PF04363 YP_002041328.1 identified by match to protein family HMM PF06445 YP_002041329.1 'removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; penicillin-binding protein 6B; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002041330.1 identified by match to protein family HMM PF01292 YP_002041331.1 identified by match to protein family HMM PF00037 YP_002041332.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409 YP_002041334.1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates YP_002041335.1 identified by match to protein family HMM PF00324 YP_002041337.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041338.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370 YP_002041339.1 long form of enzyme; catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate; crucial role in histidine biosynthesis; forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors YP_002041340.1 catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis; functions as a dimer YP_002041341.1 catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis YP_002041342.1 catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate YP_002041343.1 'with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamide ribonucleotide, and glutamate in histidine biosynthesis; the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide' YP_002041344.1 catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-phosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide YP_002041345.1 'catalyzes the conversion of 5-[(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino]- 1-(5-phosphoribosyl)imidazole-4-carboxamideand glutamine to imidazole-glycerol phosphate, 5-aminoimidazol-4-carboxamideribonucleotide and glutamate; the HisF subunit acts as a cyclase' YP_002041346.1 catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis YP_002041347.1 identified by match to protein family HMM PF02706 YP_002041348.1 identified by match to protein family HMM PF00984; match to protein family HMM PF03720; match to protein family HMM PF03721; match to protein family HMM TIGR03026 YP_002041349.1 catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate YP_002041350.1 identified by match to protein family HMM PF02397; match to protein family HMM TIGR03022; match to protein family HMM TIGR03025 YP_002041351.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002041352.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002041353.1 identified by match to protein family HMM PF00534 YP_002041354.1 identified by match to protein family HMM PF00534 YP_002041355.1 identified by match to protein family HMM PF04932 YP_002041356.1 identified by match to protein family HMM PF00535 YP_002041358.1 identified by match to protein family HMM PF00535 YP_002041360.1 identified by match to protein family HMM PF01370 YP_002041361.1 identified by match to protein family HMM PF01041 YP_002041362.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF07993; match to protein family HMM TIGR02622 YP_002041363.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR02623 YP_002041364.1 identified by match to protein family HMM PF00908; match to protein family HMM TIGR01221 YP_002041365.1 identified by match to protein family HMM PF00483; match to protein family HMM TIGR01207 YP_002041366.1 'with dTDP-4-dehydrorhamnose 3,5-epimerase forms a complex known as dTDP-L-rhamnose synthetase; catalyzes the reduction of dTDP-4-dehydro-6-deoxy-L-mannose to dTDP-L-rhamnose' YP_002041367.1 NAD(P) binding; catalyzes the formation of dTDP-4-dehydro-6-deoxy-D-glucose from dTDP-glucose YP_002041368.1 'together with GalU subunit composes the UTP--glucose-1-phosphate uridylyltransferase, an enzyme that catalyzes the formation of UDP-glucose from UTP and alpha-D-glucose 1-phosphate; regulates cellular levels of UDP-glucose' YP_002041369.1 WcaM from Salmonella enterica is essential for biofilm formation on HEp-2 cells and chicken intestinal tissue but not on a plastic surface; may be involved in the biosynthesis of colanic acid YP_002041370.1 identified by match to protein family HMM PF00534 YP_002041371.1 identified by match to protein family HMM PF04230 YP_002041372.1 identified by match to protein family HMM PF01943 YP_002041373.1 WcaJ; glucose-1-phosphate transferase responsible for the addition of the first glucose-1-phosphate from UDP-glucose to the lipid carrier undecaprenyl phosphate in the biosynthesis of colanic acid YP_002041374.1 identified by match to protein family HMM PF00408; match to protein family HMM PF02878; match to protein family HMM PF02879; match to protein family HMM PF02880 YP_002041375.1 identified by match to protein family HMM PF00483; match to protein family HMM PF01050; match to protein family HMM PF07883; match to protein family HMM TIGR01479 YP_002041376.1 identified by match to protein family HMM PF00534 YP_002041377.1 identified by match to protein family HMM PF00293 YP_002041378.1 identified by match to protein family HMM PF01370 YP_002041379.1 identified by match to protein family HMM PF01370; match to protein family HMM TIGR01472 YP_002041380.1 acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit) YP_002041381.1 identified by match to protein family HMM PF00535 YP_002041382.1 essential for colanic acid biosynthesis; colanic acid is an exopolysaccharide produced under stress conditions that confers acid and heat tolerance YP_002041384.1 'acetyltransferase believed to catalyze the addition of the acetyl group that is attached through an O linkage to the first fucosyl residue of the colanic acid repetitive unit (E unit); wcaB is induced in sessile bacteria and by osmotic shock, and repressed when grown in rich medium' YP_002041385.2 identified by match to protein family HMM PF00535 YP_002041386.1 Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide) YP_002041387.1 'Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis' YP_002041388.2 identified by match to protein family HMM PF02563 YP_002041390.1 'YegA; inner membrane protein involved in the assembly of outer membrane proteins (OMPs); asmA-null mutants show low lipopolysaccharide (LPS) levels, suggesting a role in LPS biogenesis and/or in restricting outer membrane fluidity, resulting on altered assembly of OMPs' YP_002041391.1 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis YP_002041392.1 functions in pyrimidine salvage; pyrimidine ribonucleoside kinase; phosphorylates nucleosides or dinucleosides to make UMP or CMP using ATP or GTP as the donor YP_002041394.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00989; match to protein family HMM PF00990; match to protein family HMM PF05231; match to protein family HMM PF08447; match to protein family HMM PF08448; match to protein family HMM TIGR00229; match to protein family HMM TIGR00254 YP_002041395.1 'inducible, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine' YP_002041397.1 identified by glimmer YP_002041398.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate' YP_002041399.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC which confers resistance against novobiocin and deoxycholate' YP_002041400.1 'Part of a tripartite efflux system composed of MdtA, MdtB and MdtC; confers resistance against novobiocin and deoxycholate' YP_002041401.1 identified by match to protein family HMM PF07690 YP_002041402.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002041403.1 'response regulator in two-component regulatory system with BaeS; regulator of RNA synthesis, flagellar biosynthesis, chemotaxis and transport' YP_002041406.1 identified by match to protein family HMM PF01136 YP_002041409.1 identified by glimmer YP_002041411.1 cytosolic protein with phosphatidylglycerol kinase activity; undetermined physiological role YP_002041412.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002041413.1 identified by match to protein family HMM PF03747 YP_002041414.1 identified by match to protein family HMM PF00294 YP_002041415.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002041416.1 catalyzes the formation of 4-amino-2-methyl-5-diphosphomethylpyrimidine YP_002041417.1 catalyzes the formation of 4-methyl-5-(2-phosphoethyl)-thiazole and ADP from 4-methyl-5-(2-hydroxyethyl)-thiazole and ATP YP_002041418.1 identified by glimmer YP_002041421.1 identified by match to protein family HMM PF00577 YP_002041422.1 identified by match to protein family HMM PF00345 YP_002041423.1 identified by match to protein family HMM PF00419 YP_002041426.1 methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content YP_002041427.1 identified by match to protein family HMM PF06998 YP_002041428.2 identified by match to protein family HMM PF06998 YP_002041429.1 identified by match to protein family HMM PF07308 YP_002041430.1 unknown function; when overproduced it confers drug-resistance YP_002041431.1 identified by match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF06580; match to protein family HMM PF07694 YP_002041432.1 identified by match to protein family HMM PF00376 YP_002041433.1 identified by match to protein family HMM PF00528 YP_002041434.1 identified by match to protein family HMM PF00005 YP_002041435.1 identified by match to protein family HMM PF00528 YP_002041436.1 identified by match to protein family HMM PF04069 YP_002041437.1 identified by match to protein family HMM PF00933; match to protein family HMM PF01915 YP_002041438.1 'component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent' YP_002041439.1 specifically hydrolyze the DD-diaminopimelate-alanine bonds in high-molecular-mass murein sacculi; Penicillin-binding protein 7 YP_002041440.1 identified by match to protein family HMM PF06930 YP_002041441.1 identified by match to protein family HMM PF09335 YP_002041442.1 identified by match to protein family HMM PF00106 YP_002041443.1 'may be involved in resistance to puromycin, acriflavine and tetraphenylarsonium chloride' YP_002041446.1 identified by match to protein family HMM PF01207 YP_002041447.1 catalyzes the formation of catechol from salicylate YP_002041448.1 identified by match to protein family HMM PF02798; match to protein family HMM TIGR01262 YP_002041449.1 identified by match to protein family HMM PF01557 YP_002041450.1 identified by match to protein family HMM PF07883; match to protein family HMM TIGR02272 YP_002041451.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002041452.1 identified by match to protein family HMM PF03788 YP_002041453.1 identified by match to protein family HMM PF04172; match to protein family HMM TIGR00659 YP_002041454.1 Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis YP_002041455.1 identified by match to protein family HMM PF02698 YP_002041457.1 function undetermined; similar to glutamate synthase beta subunit and related oxidoreductases which transfer electrons from NADPH to an acceptor protein or protein domain YP_002041458.1 'catalyzes the first step in pyrimidine degradation: the NADPH-dependent reduction of uracil and thymine to the corresponding 5,6-dihydropyrimidines' YP_002041459.1 ABC transporter; functions in galactose transport; part of MglA2C2B transporter complex YP_002041460.1 with MglBC transports galactose or methyl galactoside into the cell; contains 2 ATP binding domains YP_002041462.1 identified by match to protein family HMM PF00532 YP_002041463.1 negative regulator of the mglBAC operon for galactose utilization YP_002041464.1 identified by match to protein family HMM PF04171; match to protein family HMM PF04235 YP_002041465.1 'involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer' YP_002041466.1 identified by match to protein family HMM PF00756; match to protein family HMM TIGR02821 YP_002041467.1 identified by match to protein family HMM PF01381 YP_002041468.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002041469.1 identified by match to protein family HMM PF00702; match to protein family HMM PF06888; match to protein family HMM PF08282; match to protein family HMM TIGR00338; match to protein family HMM TIGR01488 YP_002041470.1 identified by match to protein family HMM PF07690 YP_002041471.1 'Cir; FeuA; CirA; receptor protein for siderophores (colicin IA, IB and V) and microcins (E492, H47, and M); TonB-dependent; able to transport monomers, dimer, and linear trimers of 2,3-dihydorxybenzoylserine; outer membrane protein' YP_002041472.1 identified by match to protein family HMM PF00324 YP_002041473.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041475.1 identified by match to protein family HMM PF03601; match to protein family HMM TIGR00698 YP_002041476.1 Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues YP_002041477.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002041478.1 'converts fructose-1-phosphate and ATP to fructose-1,6-bisphosphate and ADP; highly specific for fructose-1-phopshate; similar to PfkB; forms homodimers' YP_002041479.1 'phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIA is phosphorylated by phospho-HP which then transfers the phosphoryl group to the IIB componentr' YP_002041480.1 identified by glimmer YP_002041481.1 identified by glimmer YP_002041482.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00899 YP_002041486.1 'Stimulates the peptidyltransferase activity of the 70S ribosome and enhances dipeptide synthesis with N-formylmethionyl-tRNA and puromycin in vitro, suggesting its involvement in the formation of the first peptide bond of a protein' YP_002041487.1 identified by match to protein family HMM PF02492 YP_002041488.1 identified by match to protein family HMM PF01569 YP_002041489.2 'by similarity, Spr seems to have peptidase activity; involved in thermoresistance' YP_002041490.1 identified by match to protein family HMM PF00563 YP_002041491.1 identified by match to protein family HMM PF00496 YP_002041492.1 identified by match to protein family HMM PF00528 YP_002041493.1 identified by match to protein family HMM PF00528 YP_002041494.1 identified by match to protein family HMM PF00005; match to protein family HMM PF08352 YP_002041496.1 Involved in sulfonamide (sulfathiazole) and bicyclomycin resistance YP_002041497.1 catalyzes the synthesis pseudouridine from uracil-516 in 16S ribosomal RNA YP_002041498.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04851 YP_002041499.1 'the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response' YP_002041501.1 identified by match to protein family HMM PF04245 YP_002041502.1 identified by match to protein family HMM PF07208 YP_002041503.1 identified by match to protein family HMM PF00884 YP_002041505.1 identified by glimmer YP_002041506.1 identified by match to protein family HMM PF03406 YP_002041508.1 identified by match to protein family HMM PF09411 YP_002041509.1 nitrate/nitrite response regulator NarP; NarP is phosphorylated by NarX and NarQ and can activate fdnG and nitrite or nitrate reductase systems; represses expression of other anaerobic genes YP_002041510.1 identified by match to protein family HMM PF03918 YP_002041511.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_002041512.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_002041513.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002041514.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_002041515.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_002041516.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_002041517.1 ATP-binding protein; required for proper cytochrome c maturation YP_002041518.1 with NapABDFGH functions as a nitrate reductase; NapC functions as an electron shuttle between NapAB and NapGH or quinone YP_002041519.1 small subunit of periplasmic nitrate reductase; receives electrons from the membrane-bound NapC and passes them to NapA YP_002041520.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA YP_002041521.1 part of NapHG quinol dehydrogenase; couples electron transfer from ubiquinone-ubiquinol couple via NapC/B to NapA; secreted by twin arginine translocation pathway YP_002041522.1 periplasmic; catalytic subunit; with NapBC catalyzes the reduction of nitrate to nitrite; NapAB receives electrons from NapC YP_002041523.1 Predicted role in electron transfer to the periplasmic nitrate reductase protein NapA. YP_002041524.1 'serine protease inhibitor, inhibits trypsin and other proteases' YP_002041525.1 efflux pump for the antibacterial peptide microcin J25 YP_002041526.1 identified by match to protein family HMM PF03171 YP_002041527.1 identified by match to protein family HMM PF00165; match to protein family HMM PF01035; match to protein family HMM PF02805; match to protein family HMM PF02870; match to protein family HMM TIGR00589 YP_002041528.1 catalyzes the conversion of aminoimidazole ribotide to the 4-amino-5-hydroxymethyl-2-methyl pyrimidine moiety of thiamine; involved in the maintenance and/or assembly of sulfur clusters; periplasmic lipoporotein anchored to the inner membrane; part of the thiamine pyrophosphate biosynthesis pathway YP_002041529.1 allows for ions and hydrophilic solutes to cross the outer membrane YP_002041530.1 identified by match to protein family HMM PF01627; match to protein family HMM PF02518 YP_002041531.1 two-component response regulator RscB regulates the genes involved in capsule biosynthesis and cell division; probably phosphorylated by RcsC or RcsF YP_002041532.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518; match to protein family HMM PF09456 YP_002041533.1 negatively supercoils closed circular double-stranded DNA YP_002041534.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002041535.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690 YP_002041536.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002041537.1 Involved in ubiquinone biosynthesis YP_002041538.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002041539.1 B2 or R2 protein; type 1a enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdA YP_002041540.1 'plays a role in maintenance and possibly the biosynthesis of diferric-tyrosyl radical cofactor, essential for nucleotide reduction catalyzed by ribonucleotide reductases' YP_002041541.1 identified by match to protein family HMM PF07690 YP_002041542.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041543.1 hydrolyzes deacylated phospholipids to glycerol 3-phosphate and the corresponding alcohols; periplasmic YP_002041544.1 catalyzes the uptake of glycerol-3-phosphate into the cell with the simultaneous export of inorganic phosphate from the cell YP_002041545.1 'anaerobic, catalyzes the conversion of glycerol 3-phosphate to dihydroxyacetone using fumarate or nitrate as electron acceptor' YP_002041546.1 sn-glycerol-3-phosphate dehydrogenase (anaerobic); catalyzes the formation of dihydroxyacetone from glycerol 3-phosphate; part of GlpABC complex; presumably this subunit is responsible for membrane interactions and contains iron-sulfur clusters YP_002041547.1 anaerobic; with GlpAB catalyzes the conversion of glycerol-3-phosphate to dihydroxyacetone phosphate YP_002041548.1 'similar to ElaD; specific cysteine protease which targets ubiquitin and ubiquitin-like proteins covalently bound to target proteins; SseL in Salmonella is required for macrophage killing and virulence, and it is secreted by the salmonella pathogenicity island 2 type III secretion system' YP_002041550.1 identified by match to protein family HMM PF03328 YP_002041551.1 identified by match to protein family HMM PF07690 YP_002041552.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002041553.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002041554.1 identified by match to protein family HMM PF00994; match to protein family HMM TIGR00177; match to protein family HMM TIGR00200 YP_002041555.1 identified by match to protein family HMM PF07437 YP_002041556.1 identified by match to protein family HMM PF00293 YP_002041557.1 identified by match to protein family HMM PF00300 YP_002041558.1 catalyzes the conversion of UDP-4-keto-arabinose to UDP-4-amino-4-deoxy-L-arabinose YP_002041559.1 catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate YP_002041560.1 Bifunctional polymyxin resistance arnA protein; catalyzes the decarboxylation of UDP-glucuronic acid to UDP-4-keto-arabinose and the addition of a formyl group to UDP-4-amino-4-deoxy-L-arabinose to form UDP-L-4-formamido-arabinose; active in certain mutant strains YP_002041561.1 identified by match to protein family HMM PF01522 YP_002041562.1 catalyzes the addition of 4-amino-4-deoxy-L-arabinose to lipid A YP_002041563.1 identified by match to protein family HMM PF00893 YP_002041566.1 identified by match to protein family HMM PF00501; match to protein family HMM TIGR01923 YP_002041567.1 'catalyzes the dehydration of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid to form O-succinylbenzoate' YP_002041568.1 'catalyzes the formation of 1,4-dihydroxy-2-naphthoate from O-succinylbenzoyl-CoA' YP_002041569.1 catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA YP_002041570.1 SEPHCHC synthase; forms 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1- carboxylate from 2-oxoglutarate and isochorismate in menaquinone biosynthesis YP_002041571.1 identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543 YP_002041572.1 identified by match to protein family HMM PF05957 YP_002041573.1 identified by match to protein family HMM PF00583 YP_002041574.2 member of metallo-beta-lactamase family; the purified enzyme from Escherichia coli forms dimeric zinc phosphodiesterase; in Bacillus subtilis this protein is a 3'-tRNA processing endoribonuclease and is essential while in Escherichia coli it is not; associates with two zinc ions YP_002041575.1 identified by match to protein family HMM PF00072; match to protein family HMM PF01584 YP_002041576.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041577.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041578.1 Catalyzes the transfer of electrons from NADH to ubiquinone YP_002041579.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041580.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041581.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041582.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041583.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041584.1 'shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase' YP_002041585.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041586.1 'NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; subunits NuoCD, E, F, and G constitute the peripheral sector of the complex; in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms' YP_002041587.1 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen YP_002041588.1 Catalyzes the transfer of electrons from NADH to quinone YP_002041590.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041592.1 'broad specificity; family IV; in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor' YP_002041593.1 identified by match to protein family HMM PF01966 YP_002041594.1 identified by match to protein family HMM PF02080; match to protein family HMM PF03600; match to protein family HMM PF06808 YP_002041595.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509; match to protein family HMM TIGR01549 YP_002041596.1 identified by match to protein family HMM PF03887 YP_002041597.1 identified by match to protein family HMM PF04217 YP_002041598.1 identified by glimmer YP_002041599.1 AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation; utilizes magnesium and ATP; also involved in conversion of acetate to aceyl-CoA YP_002041600.1 catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate; when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate YP_002041601.1 identified by match to protein family HMM PF03606 YP_002041602.1 identified by match to protein family HMM PF02779; match to protein family HMM PF02780 YP_002041603.1 identified by match to protein family HMM PF00456 YP_002041604.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002041605.1 identified by match to protein family HMM PF02302 YP_002041606.1 identified by match to protein family HMM PF00359 YP_002041607.1 identified by glimmer YP_002041608.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002041609.1 identified by match to protein family HMM PF00293 YP_002041610.1 identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040 YP_002041611.1 identified by match to protein family HMM PF02798 YP_002041612.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002041613.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993; match to protein family HMM PF08338; match to protein family HMM TIGR01777 YP_002041614.1 identified by match to protein family HMM PF00005 YP_002041615.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002041616.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR01726 YP_002041617.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002041618.1 identified by match to protein family HMM PF00497; match to protein family HMM TIGR01096 YP_002041620.1 catalyzes the formation of 2-octaprenylphenol from 3-octaprenyl-4-hydroxybenzoate YP_002041621.1 identified by match to protein family HMM PF00324 YP_002041622.1 identified by match to protein family HMM PF01168 YP_002041623.1 identified by match to protein family HMM PF00324 YP_002041624.1 identified by match to protein family HMM PF00278; match to protein family HMM PF02784 YP_002041625.1 identified by match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM PF07728; match to protein family HMM PF08448; match to protein family HMM TIGR00229 YP_002041626.1 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway YP_002041627.1 membrane protein required for colicin V production YP_002041628.1 identified by match to protein family HMM PF05036 YP_002041629.1 identified by match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01499 YP_002041630.1 catalyzes the carboxylation of acetyl-CoA to malonyl-CoA; forms a tetramer of AccA2D2 subunits YP_002041631.1 identified by match to protein family HMM PF09335 YP_002041632.1 'mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability' YP_002041633.1 identified by match to protein family HMM PF01118; match to protein family HMM PF02774 YP_002041634.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002041635.1 in Salmonella typhimurium Flk regulates flagellar biosynthesis by inhibition of the flagellar-associated type III secretion system; lowers secretion levels of the anti-sigma28 factor FlgM to the periplasm; inner membrane-anchored protein YP_002041636.1 identified by match to protein family HMM PF07690 YP_002041637.1 identified by glimmer YP_002041642.1 identified by match to protein family HMM PF02517 YP_002041643.1 'FabB, beta-Ketoacyl-ACP synthase I, KASI; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP' YP_002041644.1 catalyzes the formation of 5-methylaminomethyl-2-thiouridine in position 34 of the anticodon of tRNA molecules YP_002041645.1 identified by match to protein family HMM PF08891 YP_002041646.1 identified by match to protein family HMM PF04315 YP_002041647.1 identified by match to protein family HMM PF01925 YP_002041648.1 D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm YP_002041649.1 catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis YP_002041650.1 identified by match to protein family HMM PF01713 YP_002041651.1 identified by match to protein family HMM TIGR00249 YP_002041652.1 multifunctional enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenase/3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities: forms a heterotetramer with FadI; similar to FadA2B2 complex; involved in the anaerobic degradation of long and medium-chain fatty acids in the presence of nitrate YP_002041653.1 FadI; fatty acid oxidation complex component beta; functions in a heterotetramer with FadJ; similar to FadA2B2 complex; functions in beta-oxidation of fatty acids during anaerobic growth YP_002041654.1 identified by match to protein family HMM PF04175; match to protein family HMM TIGR00743 YP_002041655.1 identified by match to protein family HMM PF03349 YP_002041656.1 identified by match to protein family HMM PF04333 YP_002041658.1 outer membrane protease; involved in virulence in many organisms; OmpT; IcsP; SopA; Pla; PgtE; omptin; in Escherichia coli OmpT can degrade antimicrobial peptides; in Yersinia Pla activates plasminogen during infection; in Shigella flexneria SopA cleaves the autotransporter IcsA YP_002041659.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954 YP_002041660.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002041662.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881 YP_002041664.1 identified by glimmer YP_002041666.1 identified by match to protein family HMM PF00155 YP_002041667.1 identified by glimmer YP_002041668.1 catalyzes the conversion of ATP and D-glucose to ADP and D-glucose 6-phosphate YP_002041669.1 identified by match to protein family HMM PF00654 YP_002041670.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776 YP_002041671.1 identified by match to protein family HMM PF00248 YP_002041673.2 identified by match to protein family HMM PF01566; match to protein family HMM TIGR01197 YP_002041674.1 identified by match to protein family HMM PF01773; match to protein family HMM PF07662; match to protein family HMM PF07670; match to protein family HMM TIGR00804 YP_002041675.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002041676.1 identified by match to protein family HMM PF07037 YP_002041677.1 identified by match to protein family HMM PF07037 YP_002041678.1 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation YP_002041679.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041680.1 identified by match to protein family HMM TIGR03510 YP_002041681.1 identified by match to protein family HMM PF03825; match to protein family HMM PF07690; match to protein family HMM TIGR00889 YP_002041682.1 catalyzes the formation of a purine and ribose phosphate from a purine nucleoside; in E. coli this enzyme functions in xanthosine degradation YP_002041683.1 identified by match to protein family HMM PF07135 YP_002041684.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041685.1 identified by match to protein family HMM PF01758 YP_002041687.1 this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction; essential for DNA replication and repair of damaged DNA; similar to ligase LigB YP_002041688.1 interacts with cell division protein FitsZ and may be required to anchor septal ring structure YP_002041689.2 role in sulfur assimilation YP_002041690.1 CysK; forms a complex with serine acetyltransferase CysE; functions in cysteine biosynthesis YP_002041692.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002041693.1 'Phosphotransferase system, enzyme I; transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein; part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active-transport system' YP_002041694.1 functions in phosphoenolpyruvate-(PEP)-dependent phosphotransferase (PTS) system; functions in the transport and phosphorylation of glucose YP_002041696.1 catalyzes the formation of pyridoxal 5'-phosphate from pyridoxal YP_002041697.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002041698.1 Catalyzes the transfer of the ammonia group from glutamine to a new carbon-nitrogen group YP_002041701.1 catalyzes the formation of cysteine from 3-O-acetyl-L-serine and hydrogen sulfide YP_002041702.1 identified by match to protein family HMM PF00005; match to protein family HMM TIGR00968 YP_002041703.1 Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import YP_002041704.1 identified by match to protein family HMM PF00528; match to protein family HMM TIGR00969; match to protein family HMM TIGR02139 YP_002041705.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002041706.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01370; match to protein family HMM PF08659 YP_002041707.1 identified by match to protein family HMM PF04261; match to protein family HMM TIGR01413 YP_002041708.1 identified by match to protein family HMM PF06572 YP_002041710.1 identified by match to protein family HMM PF00583 YP_002041711.1 identified by match to protein family HMM PF01520; match to protein family HMM TIGR01409 YP_002041712.1 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis YP_002041713.1 identified by glimmer YP_002041714.1 activates the transcription of the ethanolamine utilization operon YP_002041715.1 identified by match to protein family HMM PF00936 YP_002041716.1 identified by match to protein family HMM PF00936 YP_002041717.1 catalyzes the formation of acetaldehyde from ethanolamine YP_002041718.1 identified by match to protein family HMM PF06751 YP_002041719.1 ethanolamine utilization protein EutA YP_002041720.1 identified by match to protein family HMM PF04346 YP_002041721.1 identified by match to protein family HMM PF00465 YP_002041722.1 identified by match to protein family HMM TIGR02529 YP_002041723.1 identified by match to protein family HMM PF00171 YP_002041724.1 identified by match to protein family HMM PF03319 YP_002041725.1 in Salmonella this enzyme is required for ethanolamine catabolism; has higher affinity for CoA than Pta YP_002041726.1 identified by match to protein family HMM PF01923 YP_002041727.1 identified by match to protein family HMM PF05899; match to protein family HMM PF06249 YP_002041728.1 identified by match to protein family HMM TIGR02528 YP_002041729.1 identified by match to protein family HMM PF00936 YP_002041730.1 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate YP_002041732.1 identified by match to protein family HMM PF00923; match to protein family HMM TIGR00874 YP_002041733.1 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase' YP_002041735.1 identified by match to protein family HMM PF06674 YP_002041736.1 identified by match to protein family HMM PF00293; match to protein family HMM TIGR00052 YP_002041737.1 identified by match to protein family HMM PF00144 YP_002041738.1 'unknown function; in E. coli the aegA gene is regulated by Fnr, NarXL, and NarQ (but not ArcA), induced under anaerobic conditions and repressed in the presence of nitrate (anaerobic)' YP_002041739.1 identified by match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF07730 YP_002041740.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002041741.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR01617 YP_002041742.1 'dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.' YP_002041744.1 identified by match to protein family HMM PF00583; match to protein family HMM PF05127 YP_002041745.1 identified by match to protein family HMM PF04228 YP_002041746.1 catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase YP_002041747.1 identified by match to protein family HMM PF06804 YP_002041748.1 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis YP_002041749.1 negative transcriptional regulator of the gcvTHP operon YP_002041750.1 bacterioferritin comigratory protein; thiol peroxidase; thioredoxin-dependent; hydroperoxide peroxidase; in Escherichia coli this enzyme preferentially reduces linoleic acid hydroperoxide; contains an active site cysteine YP_002041751.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002041752.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600 YP_002041753.1 identified by match to protein family HMM PF05651 YP_002041754.1 identified by match to protein family HMM PF01594 YP_002041755.1 identified by match to protein family HMM PF01435 YP_002041756.1 identified by match to protein family HMM PF03960; match to protein family HMM TIGR00014 YP_002041757.1 'controls initiation of DNA replication by inhibiting re-initiation of replication, promotes hydrolysis of DnaA-bound ATP' YP_002041758.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002041759.1 Catalyzes the formation of uracil and 5-phospho-alpha-D-ribosy 1-diphosphate from UMP and diphosphate YP_002041760.1 identified by glimmer YP_002041761.1 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis YP_002041762.1 glycinamide ribonucleotide transformylase; GAR Tfase; catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate; PurN requires formyl folate for the reaction unlike PurT which uses formate YP_002041763.1 catalyzes the reversible transfer of the terminal phosphate of ATP to form a long chain polyphosphate YP_002041764.1 identified by match to protein family HMM PF02541 YP_002041765.1 identified by match to protein family HMM PF00563; match to protein family HMM PF05231 YP_002041769.1 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway YP_002041770.1 catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate YP_002041771.1 bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides YP_002041772.1 identified by match to protein family HMM PF05688; match to protein family HMM PF05689 YP_002041774.1 identified by glimmer YP_002041776.1 identified by match to protein family HMM PF07191 YP_002041777.1 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains YP_002041778.1 'with YaeT, YfiO, and NlpB forms a complex involved in outer membrane protein biogenesis' YP_002041780.1 'catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG' YP_002041781.1 'catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis' YP_002041782.1 identified by match to protein family HMM PF01381 YP_002041783.1 23S rRNA m2A2503 methyltransferase; methylates the C2 position of the A2530 nucleotide in 23S rRNA; may be involved in antibiotic resistance YP_002041784.1 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate YP_002041785.1 identified by match to protein family HMM PF00037 YP_002041787.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002041788.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002041789.1 penicillin-insensitive transglycosylase/transpeptidase YP_002041790.1 identified by match to protein family HMM PF01835; match to protein family HMM PF07703 YP_002041791.1 catalyzes the transfer of a sulfur ion to cyanide or to other thiol compounds YP_002041793.1 identified by glimmer YP_002041796.1 enhances serine sensitivity caused by inhibition of homoserine dehydrogenase I YP_002041797.1 catalyzes the removal of an N-terminal amino acid from a peptide or arylamide YP_002041798.1 identified by match to protein family HMM PF04384; match to protein family HMM TIGR03412 YP_002041799.1 identified by match to protein family HMM PF00111; match to protein family HMM TIGR02007 YP_002041800.1 involved in the maturation of iron-sulfur cluster-containing proteins YP_002041801.1 J-type co-chaperone that regulates the ATPase and peptide-binding activity of Hsc66 chaperone; may function in biogenesis of iron-sulfur proteins YP_002041802.1 forms iron-sulfur clusters of ferredoxin [2FE-2S]; binds iron in the presence of the thioredoxin reductase system; forms homodimers and tetramers; similar to SufA protein YP_002041803.1 identified by match to protein family HMM PF01592; match to protein family HMM TIGR01999 YP_002041804.1 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis YP_002041806.1 regulates the expression of the iscRSUA operon YP_002041807.1 identified by match to protein family HMM PF00588; match to protein family HMM TIGR00050 YP_002041808.1 identified by match to protein family HMM PF00459 YP_002041810.1 identified by match to protein family HMM TIGR02910 YP_002041811.1 with AsrAC catalyzes the reduction of sulfite to hydrogen sulfide YP_002041812.1 identified by match to protein family HMM PF00037; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM TIGR02912 YP_002041813.1 identified by match to protein family HMM PF03824 YP_002041814.1 identified by match to protein family HMM PF06226 YP_002041815.1 identified by match to protein family HMM PF00874 YP_002041816.1 transporter of 3-phenylpropionate across the inner membrane; member of the major facilitator superfamily of transporters YP_002041817.1 'catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate' YP_002041819.1 flavohemoprotein; catalyzes the formation of nitrate from nitric oxide; can also catalyze the reduction of dihydropteridine YP_002041820.1 regulates the cadBA operon YP_002041821.1 antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein YP_002041822.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002041823.1 identified by match to protein family HMM PF00854; match to protein family HMM PF07690; match to protein family HMM TIGR00924 YP_002041824.1 'indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA' YP_002041825.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF07728 YP_002041828.1 catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis YP_002041830.1 'YfhD; uncharacterized member of the transglycosylase slt family; part of the rob operon, which plays a role in cellular resistance to antibiotics, bactericidal agents, and organic solvents; unknown function' YP_002041831.1 identified by match to protein family HMM PF00383 YP_002041832.1 identified by match to protein family HMM TIGR01545 YP_002041833.1 identified by match to protein family HMM PF00367; match to protein family HMM PF02378 YP_002041834.1 catalyzes the cleavage of the lactyl ether moiety of N-acetylmuramic acid-6-phosphate (MurNAc-6-P) to form N-acetylglucosamine-6-phosphate (GlcNAc-6-P) and lactate; involved in MurNAc dissimilation pathway YP_002041835.1 identified by match to protein family HMM PF01380; match to protein family HMM PF01418 YP_002041836.1 identified by match to protein family HMM PF02558; match to protein family HMM PF08546; match to protein family HMM TIGR00745 YP_002041837.1 identified by match to protein family HMM PF07690 YP_002041838.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041839.1 identified by match to protein family HMM PF00037 YP_002041840.1 'Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids' YP_002041841.1 involved in the de novo synthesis of pyridoxine (Vitamin B6) YP_002041842.1 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA YP_002041843.1 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome YP_002041844.1 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity YP_002041845.1 catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins YP_002041846.1 binds to the ribosome on the universally-conserved alpha-sarcin loop YP_002041848.1 identified by glimmer YP_002041850.1 identified by match to protein family HMM PF02413 YP_002041851.1 identified by match to protein family HMM PF01661 YP_002041852.1 identified by match to protein family HMM PF03406; match to protein family HMM PF07484; match to protein family HMM PF08400 YP_002041854.1 identified by match to protein family HMM PF00041; match to protein family HMM PF09327 YP_002041855.2 identified by match to protein family HMM PF06805 YP_002041856.1 identified by match to protein family HMM PF05100; match to protein family HMM TIGR01600 YP_002041857.1 identified by match to protein family HMM PF05939 YP_002041858.1 identified by match to protein family HMM PF06791; match to protein family HMM PF09718; match to protein family HMM TIGR01541 YP_002041859.1 identified by match to protein family HMM PF06223; match to protein family HMM TIGR01715 YP_002041860.1 identified by match to protein family HMM PF06894; match to protein family HMM TIGR01674 YP_002041861.1 identified by match to protein family HMM PF02368 YP_002041862.1 identified by match to protein family HMM PF06141 YP_002041863.1 identified by match to protein family HMM PF01385; match to protein family HMM PF07282; match to protein family HMM TIGR01766 YP_002041864.1 identified by match to protein family HMM PF06763 YP_002041865.1 identified by match to protein family HMM PF05354 YP_002041867.1 identified by match to protein family HMM PF03864 YP_002041868.1 identified by match to protein family HMM PF02924 YP_002041869.1 identified by match to protein family HMM PF01343 YP_002041870.1 identified by match to protein family HMM PF05136; match to protein family HMM TIGR01539 YP_002041871.1 identified by match to protein family HMM PF02831 YP_002041872.1 identified by match to protein family HMM PF05876 YP_002041873.1 identified by match to protein family HMM PF07471 YP_002041874.1 identified by match to protein family HMM PF04151 YP_002041875.1 identified by match to protein family HMM PF03245 YP_002041876.1 identified by match to protein family HMM PF00959 YP_002041877.1 identified by match to protein family HMM PF05106; match to protein family HMM TIGR01594 YP_002041878.1 identified by match to protein family HMM PF07108 YP_002041879.1 identified by glimmer YP_002041881.1 identified by glimmer YP_002041882.1 identified by match to protein family HMM PF06323 YP_002041883.1 identified by match to protein family HMM PF05766 YP_002041885.1 identified by match to protein family HMM PF07105 YP_002041887.1 identified by match to protein family HMM PF06183 YP_002041888.1 identified by match to protein family HMM PF04447 YP_002041889.1 identified by match to protein family HMM PF06992 YP_002041890.1 identified by match to protein family HMM PF04492; match to protein family HMM TIGR01610 YP_002041892.1 identified by match to protein family HMM PF01656 YP_002041893.2 identified by glimmer YP_002041894.2 identified by glimmer YP_002041898.1 identified by match to protein family HMM PF06630 YP_002041899.1 identified by match to protein family HMM PF03837 YP_002041901.1 identified by match to protein family HMM PF00589 YP_002041902.1 identified by glimmer YP_002041903.1 involved in the reduction of the SoxR iron-sulfur cluster YP_002041904.1 periplasmic protein; interacts with the C-terminal domain of RseA and stimulates RseA binding to sigmaE via the cytoplasmic RseA N-terminal domain which then sequesters sigmaE in the membrane thereby preventing sigmaE associated with core RNAP YP_002041905.1 identified by match to protein family HMM PF03872; match to protein family HMM PF03873 YP_002041906.1 Member of the extracytoplasmic function sigma factors which are active under specific conditions; binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; this sigma factor is involved in heat shock and oxidative stress response YP_002041907.1 identified by glimmer YP_002041908.1 catalyzes the formation of oxaloacetate from L-aspartate YP_002041910.1 facilitates an early step in the assembly of the 50S subunit of the ribosome YP_002041911.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002041912.1 identified by match to protein family HMM PF01810 YP_002041913.1 stress-induced glycyl radical protein that can replace an oxidatively damaged pyruvate formate-lyase subunit YP_002041914.1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine YP_002041915.1 identified by match to protein family HMM PF00588; match to protein family HMM PF08032 YP_002041916.1 identified by match to protein family HMM PF00085; match to protein family HMM PF08534; match to protein family HMM TIGR01068 YP_002041917.1 identified by match to protein family HMM PF03942 YP_002041918.1 identified by match to protein family HMM PF00583; match to protein family HMM PF02629 YP_002041919.1 catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine; bounds to the ribosome YP_002041921.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002041923.1 identified by glimmer YP_002041924.1 identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728; match to protein family HMM TIGR03346 YP_002041925.1 identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726 YP_002041926.1 'responsible for synthesis of pseudouridine from uracil at positions 1911, 1915 and 1917 in 23S ribosomal RNA' YP_002041927.1 'with YaeT, NlpB and YfgL forms a complex involved in the proper assembly and/or targeting of OMPs to the outer membrane; involved in resistance to ampicillin and tetracycline' YP_002041928.1 associated with 30S ribosomal subunit; interferes with translation elongation YP_002041929.1 catalyzing the formation of prephenate from chorismate and the formation of phenylpyruvate from prephenate in phenylalanine biosynthesis YP_002041930.1 identified by match to protein family HMM PF08450 YP_002041931.1 catalyzes the formation of prephenate from chorismate and the formation of 4-hydroxyphenylpyruvate from prephenate in tyrosine biosynthesis YP_002041932.1 'catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine sensitive' YP_002041933.1 identified by glimmer YP_002041935.1 identified by match to protein family HMM PF00672; match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002041936.1 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site YP_002041937.1 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA YP_002041938.1 Essential for efficient processing of 16S rRNA YP_002041939.1 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity YP_002041940.1 with 4.5S RNA forms a signal recognition particle involved in targeting and integration of inner membrane proteins YP_002041941.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002041943.1 with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins; may act as a thermosensor YP_002041944.1 catalyzes the phosphorylation of NAD to NADP YP_002041945.1 identified by match to protein family HMM PF02463; match to protein family HMM TIGR00634 YP_002041946.1 identified by match to protein family HMM PF04355 YP_002041947.1 identified by match to protein family HMM PF03658 YP_002041948.1 identified by match to protein family HMM PF03364 YP_002041949.1 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation YP_002041950.1 identified by glimmer YP_002041951.1 identified by glimmer YP_002041952.1 identified by match to protein family HMM TIGR01965 YP_002041953.1 identified by match to protein family HMM PF02321; match to protein family HMM TIGR01844 YP_002041954.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664; match to protein family HMM TIGR03375 YP_002041955.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01843 YP_002041956.1 identified by glimmer YP_002041959.1 identified by glimmer YP_002041963.1 identified by match to protein family HMM PF02413 YP_002041964.1 identified by match to protein family HMM PF03406 YP_002041968.1 identified by match to protein family HMM TIGR01760 YP_002041970.1 identified by glimmer YP_002041973.1 identified by match to protein family HMM PF04550 YP_002041978.1 identified by match to protein family HMM PF05926 YP_002041979.1 identified by match to protein family HMM PF05944 YP_002041980.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551 YP_002041983.1 identified by match to protein family HMM PF03237; match to protein family HMM PF06056 YP_002041984.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540 YP_002041985.1 identified by match to protein family HMM PF04606 YP_002041987.1 identified by match to protein family HMM PF05840 YP_002041988.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002041991.1 identified by glimmer YP_002041992.1 identified by glimmer YP_002041993.1 identified by glimmer YP_002041994.1 identified by match to protein family HMM PF06892 YP_002041995.1 identified by glimmer YP_002041997.1 identified by match to protein family HMM PF00589 YP_002041998.1 identified by match to protein family HMM PF00589 YP_002042000.1 identified by match to protein family HMM PF01935 YP_002042001.1 identified by match to protein family HMM PF07455 YP_002042002.1 identified by match to protein family HMM PF04606 YP_002042004.1 identified by glimmer YP_002042005.1 identified by glimmer YP_002042006.1 identified by match to protein family HMM PF05930 YP_002042010.1 identified by match to protein family HMM PF01751; match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_002042011.2 identified by match to protein family HMM PF03614 YP_002042012.1 'structural flagella protein; individual Salmonella serotypes usually alternate between the production of 2 antigenic forms of flagella, termed phase 1 and phase 2, each specified by separate structural genes' YP_002042013.1 identified by match to protein family HMM PF00239; match to protein family HMM PF02796 YP_002042014.1 identified by match to protein family HMM PF06722 YP_002042015.1 identified by match to protein family HMM PF00005; match to protein family HMM PF00664 YP_002042016.1 identified by match to protein family HMM PF00756 YP_002042018.1 Fep; Cbt; Cbr; FeuB; FepA; PfeA; IroN; BfeA; outer membrane receptor of ferric enterobactin and colicins B and D; interacts with the TonB-ExbBD complex which catalyzes the translocation of the siderophore to the periplasmic space YP_002042019.1 identified by match to protein family HMM PF00805 YP_002042020.1 homologous sequence to VirK in Shigella; identified by match to protein family HMM PF04393 YP_002042021.1 identified by glimmer YP_002042022.1 identified by match to protein family HMM PF07395 YP_002042024.1 identified by match to protein family HMM PF03824; match to protein family HMM TIGR00802 YP_002042025.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518; match to protein family HMM PF08521 YP_002042026.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002042027.1 identified by match to protein family HMM PF03401 YP_002042029.1 identified by match to protein family HMM PF01970 YP_002042030.1 identified by glimmer YP_002042031.1 in Escherichia coli this gene is induced by carbon starvation and depends on sigma S and cAMP-CRP; the structure of the Gab protein shows it is a member of non-heme iron (II)-dependent oxygenase superfamily which includes clavamini acid synthases; forms homotetramers in solution YP_002042032.1 catalyzed the formation of 2-ketoglutarate from 2-hydroxyglutarate YP_002042033.1 catalyzes the formation of succinate from succinate semialdehyde; NADP dependent YP_002042034.1 catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate YP_002042035.1 identified by match to protein family HMM PF00324; match to protein family HMM TIGR01773 YP_002042036.1 regulator of gab gene expression YP_002042037.1 identified by match to protein family HMM PF01476; match to protein family HMM PF04972 YP_002042038.1 identified by match to protein family HMM PF01679 YP_002042039.1 identified by match to protein family HMM PF01022 YP_002042040.1 identified by match to protein family HMM PF00581 YP_002042042.1 identified by match to protein family HMM PF00816 YP_002042044.1 identified by match to protein family HMM PF06610 YP_002042045.1 identified by match to protein family HMM PF09400 YP_002042046.1 identified by match to protein family HMM PF05957 YP_002042047.1 identified by match to protein family HMM PF00155; match to protein family HMM PF00392 YP_002042048.1 identified by match to protein family HMM PF02627; match to protein family HMM TIGR00778 YP_002042050.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02194 YP_002042051.1 in Salmonella NrdI has a stimulatory effect on the ribonucleotide reductase activity of NrdH with NrdEF YP_002042052.1 Catalyzes the rate-limiting step in dNTP synthesis YP_002042053.1 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE YP_002042054.1 with ProWX is involved in the high-affinity uptake of glycine betaine YP_002042055.1 with ProVX is involved in the high-affinity uptake of glycine betaine YP_002042056.1 'with ProVW, part of the high-affinity transport system for the osmoprotectant glycine betaine' YP_002042057.1 identified by match to protein family HMM PF07690 YP_002042058.1 DNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; negative regulator of the multidrug operon emrAB YP_002042059.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR00998 YP_002042060.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002042063.1 catalyzes the hydrolysis of S-ribosylhomocysteine to homocysteine and autoinducer-2 YP_002042064.1 involved in the first step of glutathione biosynthesis YP_002042066.1 'YqaB; catalyzes the dephosphorylation of fructose 1-phosphate, 6-phosphogluconate and p-nitrophenyl phosphate (pNPP); presents beta-phosphoglucomutase activity at a lower extent' YP_002042067.1 affects carbohydrate metabolism; has regulatory role in many processes YP_002042068.1 'Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002042069.1 binds RecA and inhibits RecA-mediated DNA strand exchange and ATP hydrolysis and coprotease activities YP_002042070.1 'catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs' YP_002042071.1 identified by match to protein family HMM PF02464; match to protein family HMM TIGR00199 YP_002042072.1 membrane-bound lytic murein transglycosylase B; catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan YP_002042073.1 identified by match to protein family HMM PF03608; match to protein family HMM TIGR00821 YP_002042074.1 identified by match to protein family HMM PF03612; match to protein family HMM PF07663; match to protein family HMM TIGR00825 YP_002042075.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002042076.1 catalyzes the conversion of sorbitol 6-phosphate into fructose 6-phosphate YP_002042077.1 regulator for glucitol utilization YP_002042078.1 regulates genes involved in glucitol utilization YP_002042079.1 catalyzes the conversion of D-arabinose 5-phosphate to D-ribulose-5-phosphate YP_002042080.1 Required for the expression of anaerobic nitric oxide (NO) reductase; acts as a transcriptional activator for the norVW operon YP_002042081.1 detoxifies nitric oxide using NADH YP_002042082.1 catalyzes the reduction of the rubredoxin moiety of nitric oxide reductase YP_002042083.1 identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143 YP_002042084.1 involved in electron transport from formate to hydrogen YP_002042087.1 involved in the C-terminal processing of the large subunit of hydrogenase 3 HycE YP_002042088.1 identified by match to protein family HMM PF07450 YP_002042089.1 identified by match to protein family HMM PF01058 YP_002042090.1 'electron transfer protein for hydrogenase-3; the formate hydrogenlyase complex comprises of a formate dehydrogenase, unidentified electron carriers and hydrogenase-3; in this non-energy conserving pathway, molecular hydrogen and carbodioxide are released from formate' YP_002042091.1 identified by match to protein family HMM PF00329; match to protein family HMM PF00346 YP_002042092.1 identified by match to protein family HMM PF00146 YP_002042093.1 'catalyzes the oxidation of formate to carbon dioxide and molecular hydrogen; formate hydrogenlyase comprises of a formate dehydrogenase, unidentified electron carriers and a hydrogenase (subunit 3)' YP_002042094.1 identified by match to protein family HMM PF00037 YP_002042096.1 regulates several genes involved in the formate hydrogenlyase system; seems to prevent binding of FhlA transcriptional activator to the activator sequence of hyc operon YP_002042097.1 identified by glimmer YP_002042098.1 plays a role in hydrogenase nickel cofactor insertion YP_002042099.1 GTP hydrolase involved in nickel liganding into hydrogenases YP_002042100.1 'HypC; accessory protein necessary for maturation of the hydrogenase isoforms 1, 2 and 3; forms a complex with HypD, HypE, and HypF proteins, which is the site of ligand biosynthesis and attachment to the iron atom of the NiFe site in the hydrogenase' YP_002042101.1 identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075 YP_002042102.1 identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124 YP_002042103.1 identified by match to protein family HMM PF00158; match to protein family HMM PF01590; match to protein family HMM PF02954; match to protein family HMM PF07728 YP_002042105.1 identified by match to protein family HMM PF01297 YP_002042106.1 identified by match to protein family HMM PF00005 YP_002042107.1 identified by match to protein family HMM PF00950; match to protein family HMM PF01032 YP_002042108.1 identified by match to protein family HMM PF00950 YP_002042110.1 identified by match to protein family HMM PF00165 YP_002042113.1 identified by match to protein family HMM PF09482; match to protein family HMM TIGR02555 YP_002042114.1 identified by match to protein family HMM PF01514; match to protein family HMM TIGR02544 YP_002042116.1 identified by match to protein family HMM PF09392; match to protein family HMM TIGR02105 YP_002042117.2 identified by match to protein family HMM PF09480; match to protein family HMM TIGR02554 YP_002042118.1 identified by match to protein family HMM PF00165 YP_002042119.1 Activates the expression of invasion genes and activates the expression of prgHIJK which is part of the pathogenicity island 1 type III secretion system YP_002042120.1 identified by match to protein family HMM PF01464 YP_002042121.1 identified by match to protein family HMM PF00102; match to protein family HMM PF03545; match to protein family HMM PF09119 YP_002042122.1 identified by match to protein family HMM PF05932 YP_002042124.1 carries the fatty acid chain in fatty acid biosynthesis YP_002042125.1 identified by match to protein family HMM PF09052 YP_008083642.1 type III effector protein YP_008083643.1 pathogenicity island 1 effector protein SipC YP_002042126.1 identified by match to protein family HMM PF03518 YP_002042127.1 identified by match to protein family HMM PF07720; match to protein family HMM TIGR02552 YP_002042128.1 Required for surface presentation of invasion plasmid antigens; required for invasion and for secretion of the three ipa proteins YP_002042129.1 identified by match to protein family HMM PF01311; match to protein family HMM TIGR01401 YP_002042130.1 identified by match to protein family HMM PF01313; match to protein family HMM TIGR01403 YP_002042131.1 part of a type III secretory system probably involved in invasion into eukaryotic cells YP_002042132.1 involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells YP_002042133.1 identified by match to protein family HMM PF02510 YP_002042134.1 identified by match to protein family HMM PF02090 YP_002042135.1 Invasion protein InvC; necessary for efficient entry of S.typhimurium into cultured epithelial cells. Probable catalytic subunit of a protein translocase YP_002042136.1 identified by match to protein family HMM PF03519 YP_002042137.1 identified by match to protein family HMM PF00771; match to protein family HMM TIGR01399 YP_002042138.1 identified by match to protein family HMM PF02523; match to protein family HMM TIGR02568 YP_002042139.2 identified by match to protein family HMM PF00263; match to protein family HMM PF03958; match to protein family HMM TIGR02516 YP_002042140.1 identified by match to protein family HMM PF00165 YP_002042141.1 identified by match to protein family HMM PF04741 YP_002042143.1 identified by match to protein family HMM PF08681 YP_002042144.1 identified by match to protein family HMM PF00583 YP_002042146.1 identified by match to protein family HMM PF00149 YP_002042149.1 identified by glimmer YP_002042150.1 This protein performs the mismatch recognition step during the DNA repair process YP_002042152.1 identified by match to protein family HMM PF07690 YP_002042153.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042154.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791 YP_002042155.1 identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993 YP_002042156.1 identified by match to protein family HMM PF01261 YP_002042157.1 identified by match to protein family HMM PF00596 YP_002042158.1 identified by match to protein family HMM PF07005 YP_002042159.1 identified by match to protein family HMM PF03446 YP_002042160.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002042161.1 identified by match to protein family HMM PF01047 YP_002042162.1 identified by match to protein family HMM PF02441; match to protein family HMM TIGR00421 YP_002042163.1 identified by match to protein family HMM PF01977; match to protein family HMM TIGR00148 YP_002042165.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this sigma factor controls a regulon of genes required for protection against external stresses YP_002042166.1 outer membrane lipoprotein involved in stationary-phase cell survival; similar to LppB virulence determinant from Haemophilus somnus YP_002042167.1 catalyzes the methyl esterification of L-isoaspartyl residues that are formed in damaged proteins YP_002042168.1 catalyzes the conversion of a phosphate monoester to an alcohol and a phosphate YP_002042169.1 catalyzes the modification of U13 in tRNA(Glu) YP_002042170.1 'catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2,4-cyclodiphosphate' YP_002042171.1 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; MEP cytidylyltransferase; MCT; catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate; involved in isoprenoid and isopentenyl-PP biosynthesis; forms homodimers YP_002042172.1 forms a complex with FtsL and FtsQ; colocalizes to the septal region of the dividing cell; membrane protein YP_002042174.1 converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis YP_002042175.1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate; in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step; forms a heterodimer with CysD; part of the GTP-binding elongation factor family CysN/NodQ YP_002042176.1 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP YP_002042177.1 catalyzes the sequential removal of 2 amino-terminal arginines from alkaline phosphatase isozyme 1 to form isozymes 2 and 3 YP_002042179.1 identified by match to protein family HMM PF09707; match to protein family HMM TIGR01873 YP_002042180.1 identified by match to protein family HMM TIGR00287 YP_002042181.1 identified by match to protein family HMM PF08798; match to protein family HMM TIGR01907 YP_002042182.1 identified by match to protein family HMM PF09708; match to protein family HMM TIGR01868; match to protein family HMM TIGR02593 YP_002042183.1 identified by match to protein family HMM PF09344; match to protein family HMM TIGR01869 YP_002042184.1 identified by match to protein family HMM PF09485; match to protein family HMM TIGR02548 YP_002042185.1 identified by match to protein family HMM PF09481; match to protein family HMM TIGR02547 YP_002042187.1 catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite YP_002042188.1 hemoprotein; NADPH dependent; with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide YP_002042189.1 catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate; a flavoprotein with flavin reductase activity YP_002042191.1 identified by match to protein family HMM PF01242 YP_002042192.1 identified by match to protein family HMM PF00753 YP_002042193.1 identified by glimmer YP_002042195.1 identified by glimmer YP_002042196.1 identified by match to protein family HMM PF04055 YP_002042197.1 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis YP_002042198.1 CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer YP_002042199.1 functions in degradation of stringent response intracellular messenger ppGpp; in Escherichia coli this gene is co-transcribed with the toxin/antitoxin genes mazEF; activity of MazG is inhibited by MazEF in vitro; ppGpp inhibits mazEF expression; MazG thus works in limiting the toxic activity of the MazF toxin induced during starvation; MazG also interacts with the GTPase protein Era YP_002042200.1 identified by match to protein family HMM PF00419 YP_002042201.1 identified by match to protein family HMM PF00577 YP_002042202.1 identified by match to protein family HMM PF00345 YP_002042203.1 identified by match to protein family HMM PF00419 YP_002042204.1 identified by match to protein family HMM PF00419 YP_002042205.1 identified by match to protein family HMM PF00419 YP_002042207.1 (p)ppGpp synthetase; catalyzes the formation of pppGpp and ppGpp from ATP and GTP or GDP YP_002042208.1 in Escherichia coli this enzyme catalyzes the SAM-dependent methylation of U1939 in the 23S ribomal RNA; binds an iron-sulfur cluster [4Fe-4S] YP_002042209.1 part of the two-component regulatory system with UvrY; involved in the regulation of carbon metabolism via the csrA/csrB regulatory system YP_002042210.1 identified by match to protein family HMM PF02595; match to protein family HMM TIGR00045 YP_002042211.1 identified by match to protein family HMM PF01188; match to protein family HMM TIGR03247 YP_002042212.1 identified by match to protein family HMM PF01188 YP_002042213.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00893 YP_002042214.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002042215.1 catalyzes formation of pseudouridine at position 65 in tRNA-Ile1 and tRNA-Asp YP_002042216.1 identified by match to protein family HMM PF04287 YP_002042217.1 SecY regulator that either chelates excess SecY or negatively regulates the SecYE translocase function YP_002042218.1 catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) in queuosine biosynthesis YP_002042219.1 identified by match to protein family HMM PF03641 YP_002042220.1 identified by match to protein family HMM TIGR00814 YP_002042221.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002042222.2 has 3'-5' exonuclease activity that preferentially acts on ssDNA; also 3'-phosphodiesterase activity at sites with 3' incised apurinic/apyrimidinic sites; can remove 3' phosphoglycolate groups YP_002042223.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_002042224.1 catalyzes the formation of glycerone phosphate and (S)-lactaldehyde from L-fuculose 1-phosphate YP_002042226.1 identified by glimmer YP_002042227.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_002042228.1 catalyzes the conversion of the aldose L-fucose into the corresponding ketose L-fuculose YP_002042229.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR02628 YP_002042230.1 identified by match to protein family HMM PF05025 YP_002042231.1 regulates expression of genes involved in L-fucose utilization YP_002042233.1 identified by match to protein family HMM PF04241 YP_002042234.1 Glycine cleavage system transcriptional activator; activates the gcvTHP operon in the presence of glycine and represses the operon in its absence YP_002042235.1 identified by match to protein family HMM PF06004 YP_002042236.1 identified by match to protein family HMM PF00266; match to protein family HMM TIGR03392 YP_002042237.1 identified by match to protein family HMM PF02657; match to protein family HMM TIGR03391 YP_002042238.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002042239.1 identified by match to protein family HMM PF00899 YP_002042240.1 catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis YP_002042241.1 helicase/nuclease; with RecBC catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002042242.1 helicase/nuclease; with RecCD catalyzes the exonucleolytic cleavage of DNA; RecD has 5' to 3' helicase activity YP_002042243.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002042244.1 catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides; component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination YP_002042245.1 identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532 YP_002042246.1 'alternate name YgdB, URF2; orf of X03966; 2nd start; ORF_f121' YP_002042248.1 identified by match to protein family HMM TIGR02532 YP_002042250.1 'ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived' YP_002042251.1 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein YP_002042252.1 identified by glimmer YP_002042253.1 member of a second PTS chain involved in nitrogen metabolism; PtsP phosphorylates NPr YP_002042254.1 hydrolyzes diadenosine polyphosphate YP_002042255.1 MutH; Sequence-specific endonuclease that cleaves unmethylated GATC sequences during DNA repair YP_002042256.1 identified by match to protein family HMM PF03741 YP_002042257.1 identified by match to protein family HMM PF06004 YP_002042258.1 complements the prephenate dehydrogenase dysfunction of an Escherichia coli tyrosine auxotroph strain; member of the aldo/keto reductase 2 family; crystal structure of purified Escherichia coli protein shows bound NADPH YP_002042259.1 identified by match to protein family HMM PF07690 YP_002042260.1 Transfers fatty acids to the 1-position via an enzyme-bound acyl-ACP intermediate in the presence of ATP and magnesium. Its physiological function is to regenerate phosphatidylethanolamine from 2-acyl-glycero-3-phosphoethanolamine (2-acyl-GPE) formed by transacylation reactions or degradation by phospholipase A1 YP_002042262.1 controls transcription of galETKM YP_002042263.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002042264.1 catalyzes the decarboxylation of diaminopimelate into lysine; pyridoxal phosphate(PLP)-binding YP_002042265.1 activates the transcription of the lysA gene encoding diaminopimelate decarboxylase YP_002042266.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002042267.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002042268.1 catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate YP_002042269.1 '4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase; catalyzes the interconversion of 4-deoxy-L-threo-5-hexosulose uronate to 3-deoxy-D-glycero-2,5-hexodiulosonate' YP_002042270.1 identified by glimmer YP_002042271.1 'Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; in Rhizobia and Ralstonia is involved in PHB biosynthesis' YP_002042272.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042273.1 identified by match to protein family HMM PF05232 YP_002042275.1 identified by match to protein family HMM PF02583 YP_002042276.1 membrane protein conferring nickel and cobalt resistance YP_002042278.1 identified by match to protein family HMM PF07180 YP_002042279.1 identified by match to protein family HMM PF00345 YP_002042280.1 identified by match to protein family HMM PF00577 YP_002042281.1 identified by match to protein family HMM PF00419 YP_002042282.1 identified by glimmer YP_002042284.1 identified by match to protein family HMM PF06316 YP_002042286.1 stability determinant protein YP_002042289.1 identified by match to protein family HMM PF07313 YP_002042290.1 identified by match to protein family HMM PF01476; match to protein family HMM PF01551 YP_002042291.1 catalyzes the rearrangement of isopentenyl diphosphate to dimethylallyl phosphate YP_002042292.1 'class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1' YP_002042293.1 5'-3' single-stranded-DNA-specific exonuclease YP_002042294.1 DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity YP_002042295.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; XerD specifically exchanges the bottom strands; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002042296.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic' YP_002042297.1 identified by match to protein family HMM PF07254 YP_002042298.1 identified by match to protein family HMM PF03937 YP_002042300.1 physiological role is not clear; not essential for growth but mutants grow poorly; mutations suppress hda null mutations; may be involved in regulation of ATP-DnaA levels; may also be involved in regulation of tRNA modifications; can bind folic acid and tetrahydrofolate; forms a three domain ring-like structure with a central channel; structurally similar to DMGO protein from A. globiformis; shows sequence similarity to yeast CAF17 transcriptional regulator YP_002042301.1 identified by match to protein family HMM PF03006; match to protein family HMM TIGR01065 YP_002042302.1 identified by match to protein family HMM PF04266 YP_002042303.1 identified by match to protein family HMM PF00232 YP_002042305.1 acts in conjunction with GvcH to form H-protein-S-aminomethyldihydrolipoyllysine from glycine YP_002042306.1 'part of multienzyme complex composed of H, L, P, and T proteins which catalyzes oxidation of glycine to yield carbon dioxide, ammonia, 5,10-CH2-H4folate and a reduced pyridine nucleotide; protein H is involved in transfer of methylamine group from the P to T protein; covalently bound to a lipoyl cofactor' YP_002042307.1 'catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein' YP_002042308.1 identified by match to protein family HMM PF01494; match to protein family HMM TIGR01988 YP_002042310.1 'Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone' YP_002042311.1 exopeptidase able to cleave the peptide bond of the last amino acid if linked to a proline residue; substrate can be as short as a dipeptide YP_002042312.1 the crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown YP_002042313.1 identified by match to protein family HMM PF05164 YP_002042314.1 ygfA expression increases five to eight fold in Escherichia coli cells growing as biofilms; unknown function YP_002042315.1 catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate YP_002042316.1 specific inhibitor of chromosomal initiation of replication in vitro; binds the three 13-mers in the origin (oriC) to block initiation of replication; also controls genes involved in arginine transport YP_002042318.1 identified by match to protein family HMM PF04402 YP_002042319.1 Involved in the export of arginine YP_002042321.1 participates in the regulation of osmotic pressure changes within the cel YP_002042322.1 'catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1,6, bisphosphate' YP_002042323.1 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway YP_002042324.1 NAD-dependent; catalyzes the formation of 4-phosphoerythronate from erythrose 4-phosphate in the biosynthesis of pyridoxine 5'-phosphate YP_002042325.1 identified by match to protein family HMM PF03479 YP_002042327.1 identified by match to protein family HMM PF02361 YP_002042328.1 identified by match to protein family HMM PF00005 YP_002042329.1 identified by match to protein family HMM PF00005 YP_002042331.1 identified by match to protein family HMM PF05068 YP_002042332.1 identified by match to protein family HMM PF03320; match to protein family HMM TIGR00330 YP_002042333.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002042334.1 identified by match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002042335.1 'TolM; with CmtA (IIBC), CmtB possibly forms the mannitol-like permease component of the cryptic mannitol phosphotransferase system, which phosphorylates and transports various carbohydrates and polyhydric alcohols in Escherichia coli; cytoplasmic protein' YP_002042336.1 'catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during exponential growth and the tktB during stationary phase' YP_002042337.1 catalyzes the formation of putrescine from agmatine YP_002042338.1 identified by match to protein family HMM PF00561 YP_002042339.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002042340.1 identified by match to protein family HMM PF02615 YP_002042341.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002042342.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002042343.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002042345.2 catalyzes the formation of agmatine from arginine in putrescine and spermidine biosynthesis YP_002042348.1 catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase YP_002042349.1 identified by glimmer YP_002042350.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00879 YP_002042351.1 identified by match to protein family HMM PF03926 YP_002042352.1 identified by match to protein family HMM PF04231 YP_002042353.1 'in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase' YP_002042354.1 'catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione' YP_002042355.1 identified by match to protein family HMM PF02622 YP_002042356.1 similar to RuvC resolvase with substantial differences; NMR structural information suggests this protein is monomeric; unknown cellular function YP_002042357.1 identified by match to protein family HMM PF09339 YP_002042358.1 identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420 YP_002042359.1 identified by match to protein family HMM PF01168; match to protein family HMM TIGR00044 YP_002042360.1 identified by match to protein family HMM PF02325 YP_002042361.1 identified by match to protein family HMM PF02594; match to protein family HMM TIGR00251 YP_002042362.1 HAM1-like protein; Rec-dependent growth; RgdB; yggV; it is suspected that this protein functions to remove misincorporated bases such as xanthine or hypoxanthine YP_002042363.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002042364.1 identified by match to protein family HMM PF06717 YP_002042365.1 'catalyzes the formation of aspartate from asparagine, periplasmic; regulated by cyclic AMP receptor protein (CRP) and also induced by anaerobiosis' YP_002042368.1 identified by match to protein family HMM PF04320 YP_002042369.1 tRNA (guanine-N(7)-)-methyltransferase; catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA by transferring the methyl residue from S-adenosyl-L-methionine YP_002042370.1 identified by match to protein family HMM PF00633; match to protein family HMM PF00730; match to protein family HMM TIGR01084 YP_002042371.1 identified by match to protein family HMM PF04362 YP_002042372.1 'Murein hydrolase C; membrane-bound; lytic; catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues' YP_002042374.1 identified by match to protein family HMM PF03825; match to protein family HMM TIGR00889 YP_002042375.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002042376.1 identified by glimmer YP_002042377.1 identified by match to protein family HMM PF04474 YP_002042378.1 identified by match to protein family HMM PF02550 YP_002042379.1 identified by match to protein family HMM PF01575 YP_002042380.1 identified by match to protein family HMM PF03328 YP_002042381.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042382.1 identified by match to protein family HMM PF00884 YP_002042383.1 identified by match to protein family HMM PF04055 YP_002042384.1 identified by match to protein family HMM PF00196 YP_002042386.1 identified by match to protein family HMM PF00324 YP_002042387.1 identified by glimmer YP_002042388.1 identified by match to protein family HMM PF05899 YP_002042389.1 identified by match to protein family HMM PF01266 YP_002042390.1 identified by match to protein family HMM PF00171 YP_002042392.2 inhibitor of RssB activity in response to DNA damage; blocks degradation of stationary phase sigma factor RpoS YP_002042393.1 identified by match to protein family HMM PF05638; match to protein family HMM TIGR03344 YP_002042395.1 identified by match to protein family HMM PF01522 YP_002042396.1 identified by match to protein family HMM PF00795 YP_002042397.1 identified by match to protein family HMM PF07690 YP_002042398.1 catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate from mannonate YP_002042399.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002042400.1 catalyzes the interconversion of D-glucuronate to D-fructuronate or D-galacturonate to D-tagaturonate; functions in glucuronic and galacturonic metabolism YP_002042401.1 identified by match to protein family HMM PF00015 YP_002042403.1 catalyzes the formation of glutathionylspermidine from glutathione and spermidine; also catalyzes the reverse reaction YP_002042404.1 YghU; B2989; one of eight glutathione transferase proteins from E. coli YP_002042406.1 identified by match to protein family HMM PF01497 YP_002042407.1 identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074 YP_002042408.1 plays a role in hydrogenase nickel cofactor insertion YP_002042410.1 protease responsible for the cleavage of a 15 amino acid peptide from the C-terminal end of the large subunit of hydrogenase 2 (HybC) YP_002042411.1 involved in hydrogen uptake YP_002042412.1 'HybB; cytochrome b subunit of the hydrogenase 2 enzyme, composed of HybA, B, C, and O subunits' YP_002042413.1 Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2 YP_002042414.1 involved in hydrogen uptake YP_002042417.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002042418.1 identified by match to protein family HMM PF03350; match to protein family HMM TIGR00645 YP_002042422.1 identified by match to protein family HMM PF00106 YP_002042423.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002042424.1 membrane spanning protein in TonB-ExbB-ExbD complex; involved in the tonB-independent energy-dependent transport iron-siderophore complexes and vitamin B12 into the cell YP_002042426.1 catalyzes the formation of L-homocysteine from cystathionine YP_002042427.1 identified by match to protein family HMM PF09335 YP_002042428.1 identified by glimmer YP_002042429.1 identified by match to protein family HMM PF00465 YP_002042430.1 'methylglyoxal reductase/#-keto ester reductase; catalyzes the reduction of 2,5-diketo-D-gluconic acid to 2-keto-L-gulonic acid; also catalyzes the reduction of methylglyoxal, ethyl-2-methylacetoacetate and ethyl-acetoacetate' YP_002042431.1 identified by match to protein family HMM PF01230 YP_002042432.1 identified by glimmer YP_002042433.1 identified by match to protein family HMM PF04055; match to protein family HMM PF08497 YP_002042434.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_002042435.1 identified by match to protein family HMM PF04290 YP_002042436.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_002042437.1 identified by match to protein family HMM PF07731; match to protein family HMM PF07732; match to protein family HMM TIGR01409 YP_002042438.1 identified by match to protein family HMM PF01553; match to protein family HMM TIGR00530 YP_002042439.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002042440.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002042441.1 identified by match to protein family HMM PF04076; match to protein family HMM TIGR00156 YP_002042442.1 response regulator in two-component regulatory system with QseC; regulates FlhCD which is the master regulator for flagella and motility genes YP_002042443.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002042444.1 identified by glimmer YP_002042445.1 identified by match to protein family HMM PF02525 YP_002042446.1 identified by match to protein family HMM PF03992 YP_002042447.1 identified by glimmer YP_002042448.1 decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling YP_002042449.1 Displays esterase activity toward palmitoyl-CoA and pNP-butyrate YP_002042450.1 identified by match to protein family HMM PF00149; match to protein family HMM PF08413 YP_002042451.1 identified by match to protein family HMM PF06853 YP_002042452.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002042453.1 trimeric outer membrane protein involved in efflux of hydrophobic/amphipathic molecules; functions with a number of efflux systems in the inner membrane to transport molecules out of the cell YP_002042455.1 identified by match to protein family HMM PF03738 YP_002042456.1 'seems to be involved in biofilm formation; in asymptomatic bacteriuria E. coli strains 83972 and VR50, the ygiD gene is upregulated during biofilm formation in urine' YP_002042457.1 identified by match to protein family HMM PF02535 YP_002042459.1 identified by match to protein family HMM PF05935 YP_002042460.1 identified by match to protein family HMM PF01323 YP_002042462.1 DHBP synthase; functions during riboflavin biosynthesis YP_002042463.1 identified by match to protein family HMM PF04380 YP_002042464.1 Involved in glycogen synthesis. May be involved in glycogen priming YP_002042465.1 identified by match to protein family HMM PF07290 YP_002042466.1 identified by match to protein family HMM PF01145 YP_002042467.1 'catalyzes the phosphorylation of D-glycero-D-manno-heptose 7-phosphate to form D,D-heptose-1,7-bisphosphate and catalyzes transfer of ADP to D-glycero-D-manno-heptose 1-phosphate forming ADP-D,D-heptose' YP_002042468.1 catalyzes the ATP-dependent addition of AMP to a subunit of glutamine synthetase; also catalyzes the reverse reaction - deadenylation; adenylation/deadenylation of glutamine synthetase subunits is important for the regulation of this enzyme YP_002042469.1 identified by match to protein family HMM PF01928; match to protein family HMM PF05235 YP_002042470.1 identified by match to protein family HMM PF08239 YP_002042471.1 'catalyzes the addition and repair of the essential 3'-terminal CCA sequence in tRNAs without using a nucleic acid template; phosphohydrolase activities include hydrolysis of pyrophosphate, 5'-nucleoside tri- and diphosphates, NADP, and 2'-AMP with the production of Pi, metal-dependent phosphodiesterase activity for 2',3'-cAMP, 2',3'-cGMP, and 2',3'-cCMP, and hydrolysis 2',3'-cyclic substrates with the formation of 2'-nucleotides and 3'-nucleotides; these phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases' YP_002042472.1 BacA; phosphatase activity in Escherichia coli not kinase; involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell YP_002042473.1 'catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin' YP_002042474.1 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsX YP_002042475.1 'in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity' YP_002042476.1 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA YP_002042477.1 synthesizes RNA primers at the replication forks YP_002042478.1 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; this is the primary sigma factor of bacteria YP_002042479.1 identified by match to protein family HMM PF03167 YP_002042480.1 identified by match to protein family HMM PF04954; match to protein family HMM PF08021 YP_002042481.1 identified by match to protein family HMM PF03551 YP_002042482.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672 YP_002042483.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF08447; match to protein family HMM TIGR00229 YP_002042485.1 catalyzes the formation of 4-aminobutyraldehyde from putrescine and 2-oxoglutarate YP_002042486.1 identified by match to protein family HMM PF00724; match to protein family HMM PF07992 YP_002042487.1 identified by match to protein family HMM PF05175; match to protein family HMM PF08242 YP_002042488.1 identified by match to protein family HMM PF01863 YP_002042489.1 identified by match to protein family HMM PF02698 YP_002042490.1 identified by match to protein family HMM PF01408 YP_002042491.1 identified by match to protein family HMM PF03741 YP_002042492.1 involved in the import of serine and threonine coupled with the import of sodium YP_002042493.1 identified by match to protein family HMM PF09335 YP_002042495.1 identified by match to protein family HMM PF06476 YP_002042496.1 identified by match to protein family HMM PF05957 YP_002042499.1 identified by match to protein family HMM PF07681 YP_002042501.1 identified by match to protein family HMM PF05656 YP_002042502.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042504.1 identified by match to protein family HMM PF06354 YP_002042505.1 identified by match to protein family HMM TIGR00814 YP_002042506.1 identified by match to protein family HMM PF03313; match to protein family HMM PF03315; match to protein family HMM TIGR00720 YP_002042507.1 identified by match to protein family HMM PF01228; match to protein family HMM PF02901; match to protein family HMM TIGR01255 YP_002042508.1 catalyzes the formation of propanoyl phosphate from propanoate and ATP; TdcD also has acetate kinase activities and functions in anaerobic threonine catabolism YP_002042509.1 involved in the import of threonine and serine in combination with the import of a proton YP_002042510.1 catalyzes the formation of 2-oxobutanoate from L-threonine; catabolic YP_002042511.1 regulates the tdcABCDEFG operon which is involved in amino acid degradation YP_002042512.1 catalyzes the reduction of tartronate semialdehyde to glycerate YP_002042513.1 cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate YP_002042514.1 identified by glimmer YP_002042515.1 identified by match to protein family HMM PF04295; match to protein family HMM PF08666; match to protein family HMM TIGR03248 YP_002042516.1 'catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in enteric bacteria there are two D-tagatose 1,6-bisphosphate-specific aldolases: KbaY (also called AgaY), involved in catabolism of N-acetyl-galactosamine and D-galactosamine, and GatY which is part of the galactitol catabolism pathway' YP_002042517.1 identified by match to protein family HMM PF08013; match to protein family HMM TIGR02810 YP_002042518.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002042519.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002042520.1 identified by match to protein family HMM PF03611; match to protein family HMM TIGR00827 YP_002042521.1 Zn-dependent; NAD(P)-binding; catalyzes the formation of tagatose-6-phosphate from galactitol-1-phosphate YP_002042522.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002042523.1 identified by match to protein family HMM PF00590; match to protein family HMM TIGR00096 YP_002042524.1 identified by match to protein family HMM PF04348 YP_002042525.1 identified by match to protein family HMM PF02021; match to protein family HMM TIGR00252 YP_002042526.1 Required for the timely initiation of chromosomal replication via direct interactions with the dnaA initiator protein YP_002042527.1 identified by match to protein family HMM PF04972 YP_002042528.1 identified by match to protein family HMM PF01370; match to protein family HMM PF07993 YP_002042529.1 identified by match to protein family HMM PF01965; match to protein family HMM TIGR01382 YP_002042531.1 identified by match to protein family HMM PF01541 YP_002042532.1 identified by match to protein family HMM PF00583 YP_002042533.1 identified by match to protein family HMM PF02036 YP_002042534.1 identified by match to protein family HMM PF01136 YP_002042535.1 identified by match to protein family HMM PF01136 YP_002042536.1 identified by match to protein family HMM PF00296; match to protein family HMM TIGR03558 YP_002042537.1 tryptophan transporter of high affinity YP_002042538.1 participates in the assembly of the large subunit of the ribosome; plays a key role in optimal cell growth at low temperature and is required for normal cell division YP_002042539.1 lipoprotein that appears to be involved in cell division; interacts with the periplasmic protease Prc and may be activated by protease processing YP_002042540.1 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence YP_002042541.1 catalyzes isomerization of specific uridines in RNA to pseudouridine; responsible for residues in T loops of many tRNAs YP_002042542.1 associates with free 30S ribosomal subunits; essential for efficient processing of 16S rRNA; in Escherichia coli rbfA is induced by cold shock YP_002042543.1 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex YP_002042544.1 'modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination' YP_002042545.1 in Streptococcus pneumoniae this gene was found to be essential; structure determination of the Streptococcus protein shows that it is similar to a number of other proteins YP_002042546.1 identified by glimmer YP_002042547.1 catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis YP_002042549.1 identified by match to protein family HMM PF03840; match to protein family HMM TIGR00810 YP_002042550.1 catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate YP_002042551.1 'catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate' YP_002042552.1 inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins YP_002042553.1 Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit YP_002042554.1 RNA binding protein found associated to pre-50S subunit of the ribosome; role in ribosome assembly; necessary for optimal growth but not cell viability YP_002042555.1 'necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus' YP_002042556.1 identified by glimmer YP_002042557.1 'penicillin binding protein 4; penicillin sensitive; catalyzes the formation of D-alanine from D-alanyl-D-alanine; one of four, DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains' YP_002042559.1 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication YP_002042560.1 identified by match to protein family HMM PF00892 YP_002042561.1 involved in the peptidyltransferase reaction during translation YP_002042562.1 identified by match to protein family HMM PF00829; match to protein family HMM TIGR00061 YP_002042563.2 identified by match to protein family HMM PF00348 YP_002042564.1 activator of maltose metabolism genes YP_002042565.1 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active YP_002042566.1 identified by match to protein family HMM PF01722 YP_002042568.1 identified by match to protein family HMM PF05494 YP_002042569.1 identified by match to protein family HMM PF02470 YP_002042570.1 identified by match to protein family HMM PF02405; match to protein family HMM TIGR00056 YP_002042571.1 ATP-binding subunit of a ABC toluene efflux transporter YP_002042572.1 YrbG; inner membrane protein involved in cell envelope integrity; sodium ion/calcium ion exchanger; in E. coli it is non essential for cell viability; member of the YRBG family of cation/Ca2+ exchangers YP_002042573.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01380; match to protein family HMM TIGR00393 YP_002042574.1 forms homotetramers; catalyzes hydrolysis of KDO 8-P to KDO and inorganic phosphate; functions in lipopolysaccharide biosynthesis YP_002042575.1 identified by match to protein family HMM PF06835 YP_002042576.1 'LptA; periplasmic binding protein part of a ABC superfamily of uptake transporters; interacts with LptB protein, the ATP binding component of the uptake system' YP_002042577.1 identified by match to protein family HMM PF00005 YP_002042578.1 'sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released; sigma 54 factor is responsible for the expression of enzymes involved in nitrogen assimilation and metabolism; the rhizobia often have 2 copies of this sigma factor; in Rhizobium etli RpoN1 shown to be involved in the assimilation of several nitrogen and carbon sources during free-living aerobic growth and RpoN2 is involved in symbiotic nitrogen fixation; in Bradyrhizobium both RpoN1 and N2 are functional in free-living and symbiotic conditions, rpoN1 gene was regulated in response to oxygen' YP_002042579.1 YhbH; resting ribosome-binding protein involved in ribosome stabilization and preservation in stationary phase; binds specifically 100S ribosomes (an inactive ribosome product of a 70S ribosome dimerization); seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing YP_002042580.1 identified by match to protein family HMM PF00359; match to protein family HMM TIGR01419 YP_002042581.1 identified by match to protein family HMM PF03668 YP_002042582.1 N-regulated PTS system (Npr); identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002042584.1 glycosyltransferase; polymerizes glycan strands in the peptidoglycan YP_002042585.1 identified by match to protein family HMM PF01965 YP_002042586.1 sensor-regulator protein which regulates the expression of many genes in response to respiratory growth conditions including anaerobic repression of the arc modulon; hybrid sensory histidine kinase in two-component regulatory system with ArcA YP_002042587.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR01212 YP_002042588.1 'glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate' YP_002042589.1 identified by match to protein family HMM PF02133 YP_002042590.1 Catalyzes the deamination of cytosine to uracil and ammonia YP_002042591.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002042592.1 catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein YP_002042593.1 Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate YP_002042594.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00891 YP_002042595.1 catalyzes the formation of pyruvate and N-acetylmannosamine from N-acetylneuraminic acid YP_002042596.1 Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization YP_002042597.1 identified by match to protein family HMM PF04386 YP_002042598.1 transcriptional activator; required for activation of bacteriophage P1 late promoter; induced by starvation YP_002042599.1 forms a direct contact with the tRNA during translation YP_002042600.1 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit YP_002042601.1 identified by match to protein family HMM PF03969 YP_002042602.1 identified by match to protein family HMM PF06295 YP_002042603.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02037 YP_002042604.1 identified by match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038 YP_002042606.1 identified by match to protein family HMM PF03977; match to protein family HMM TIGR01109 YP_002042607.1 catalyzes the formation of pyruvate from oxaloacetate YP_002042608.1 catalyzes the decarboxylation of oxaloacetate to form pyruvate and carbon dioxide YP_002042609.1 Involved in the tartrate degradation pathway YP_002042610.1 Involved in the tartrate degradation pathway YP_002042611.1 identified by match to protein family HMM PF00939; match to protein family HMM PF02040; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00785 YP_002042612.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002042613.1 identified by match to protein family HMM PF00392 YP_002042614.1 oxidizes malate to oxaloacetate YP_002042615.1 regulates arginine biosynthesis when complexed with arginine by binding at site that overlap the promotors of the arginine biosynthesis genes YP_002042616.1 identified by match to protein family HMM PF07338 YP_002042617.1 identified by match to protein family HMM PF07338 YP_002042619.1 with AaeA forms an efflux pump whose substrates are p-hydroxybenzoic acid 6-hydroxy-2-naphthoic and 2-hydroxycinnamate YP_002042620.1 'with AaeB forms an efflux pump whose substrates are p-hydroxybenzoic acid, 6-hydroxy-2-naphthoic and 2-hydroxycinnamate' YP_002042621.1 membrane protein AaeX; the gene is a member of the aaeXAB operon YP_002042622.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042623.1 'responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase; degrades the E. coli plasmid F-encoded CcdA' YP_002042624.1 identified by match to protein family HMM TIGR02099 YP_002042625.1 involved in the processing of the 5'end of 16S rRNA YP_002042626.1 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell YP_002042627.1 part of cell wall structural complex MreBCD; transmembrane component YP_002042628.1 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall YP_002042629.1 functions in MreBCD complex in some organisms YP_002042630.1 regulates the degradation of the small RNAs CsrB and CsrC; may function to targate RNase E to specific RNA molecules YP_002042631.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240; match to protein family HMM TIGR02823 YP_002042632.1 in Escherichia coli this periplasmic enzyme was found to encode the periplasmic catalytic subunit of an oxidoreductase; sulfite oxidase activity not demonstrated; requires inner membrane anchor protein YedZ YP_002042633.1 in Escherichia coli this inner membrane protein was found to anchor the periplasmic catalytic oxidoreductase YedY; sulfite oxidase activity not demonstrated; contains heme YP_002042634.1 'composes the biotin carboxyl carrier protein subunit of the acetyl-CoA carboxylase complex, the enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, which in turn controls the rate of fatty acid metabolism' YP_002042635.1 'an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism' YP_002042636.1 identified by match to protein family HMM PF06196 YP_002042637.1 mediates high affinitiy panthothenate transport which is stimulated by the presence of sodium ions; member of SSS family of sodium/solute symporters; the imported panthothenate is phosphorylated by panthothenate kinase YP_002042638.1 methylates ribosomal protein L11 at multiple amino acid positions; mutations of these genes in Escherichia coli or Thermus thermophilus has no apparent phenotype YP_002042639.1 identified by glimmer YP_002042640.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00737 YP_002042641.1 Stimulates excision of phage lambda; affects Mu development; acts as an activator of rRNA and iRNA transcription YP_002042642.1 identified by match to protein family HMM PF01555 YP_002042644.1 identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM PF03707; match to protein family HMM TIGR00254 YP_002042645.1 identified by match to protein family HMM PF00440; match to protein family HMM PF08361 YP_002042647.1 identified by match to protein family HMM PF00529; match to protein family HMM TIGR01730 YP_002042648.1 identified by match to protein family HMM PF00873; match to protein family HMM TIGR00915 YP_002042650.1 identified by glimmer YP_002042651.1 identified by glimmer YP_002042652.1 identified by match to protein family HMM PF07369 YP_002042653.1 AroE; catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002042654.1 RimN; YrdC; required for maturation of 16s RNA; binds preferentially double stranded RNA YP_002042655.1 identified by match to protein family HMM PF01396 YP_002042656.1 identified by match to protein family HMM PF04361 YP_002042657.1 identified by match to protein family HMM PF02481; match to protein family HMM TIGR00732 YP_002042658.1 cleaves off formyl group from N-terminal methionine residues of newly synthesized proteins; binds iron(2+) YP_002042659.1 modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation; inactivation of this gene in Escherichia coli severely impairs growth YP_002042660.1 catalyzes the methylation of cytosine at position 967 (m5C967) of 16S rRNA; SAM-dependent methyltransferase YP_002042661.1 involved in potassium uptake; found to be peripherally associated with the inner membrane in Escherichia coli; contains an NAD-binding domain YP_002042662.1 forms homopentamer; channel that opens in response to pressure or hypoosmotic shock YP_002042663.1 mediates expression of the zinc export protein ZntA in response to high levels of zinc; member of MerR family of transcriptional regulators YP_002042664.1 identified by match to protein family HMM PF09350 YP_002042665.1 is a component of the macrolide binding site in the peptidyl transferase center YP_002042666.1 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme YP_002042667.1 primary rRNA binding protein; nucleates 30S assembly; involved in translational accuracy with proteins S5 and S12; interacts with protein S5; involved in autogeneously regulating ribosomal proteins by binding to pseudoknot structures in the polycistronic mRNA; interacts with transcription complex and functions similar to protein NusA in antitermination YP_002042668.1 'located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3' YP_002042669.1 'located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA' YP_002042670.1 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase YP_002042671.1 late assembly protein YP_002042672.1 L30 binds domain II of the 23S rRNA and the 5S rRNA; similar to eukaryotic protein L7 YP_002042673.1 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance YP_002042674.1 binds 5S rRNA along with protein L5 and L25 YP_002042675.1 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance YP_002042676.1 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit YP_002042677.1 'located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit; similar to what is observed with proteins L31 and L33, some proteins in this family contain CXXC motifs that are involved in zinc binding; if two copies are present in a genome, then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc; the proteins in this group do not appear to have the zinc-binding motif' YP_002042678.1 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13 YP_002042679.1 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel YP_002042680.1 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase YP_002042681.1 primary binding protein; helps mediate assembly; involved in translation fidelity YP_002042682.1 one of the stabilizing components for the large ribosomal subunit YP_002042683.1 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e YP_002042684.1 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation YP_002042685.1 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center YP_002042686.1 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA YP_002042687.1 'one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation' YP_002042688.1 binds third domain of 23S rRNA and protein L29; part of exit tunnel YP_002042689.1 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA YP_002042690.1 'binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin' YP_002042691.1 identified by match to protein family HMM PF00338; match to protein family HMM TIGR01049 YP_002042692.1 identified by match to protein family HMM PF01478 YP_002042693.1 iron storage protein YP_002042694.1 identified by match to protein family HMM PF04324 YP_002042695.1 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu' YP_002042696.1 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene YP_002042697.1 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit YP_002042698.1 'interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance' YP_002042699.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002042700.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002042701.1 in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs YP_002042702.1 identified by match to protein family HMM PF08348 YP_002042703.1 rotamase YP_002042704.1 identified by match to protein family HMM PF04102 YP_002042705.1 rotamase YP_002042706.1 identified by match to protein family HMM PF09526; match to protein family HMM TIGR02443 YP_002042707.1 involved in potassium efflux YP_002042708.1 required for KefB activity YP_002042709.1 identified by match to protein family HMM PF00005 YP_002042711.1 identified by match to protein family HMM PF08803 YP_002042712.1 identified by glimmer YP_002042713.1 identified by match to protein family HMM PF00561 YP_002042714.1 identified by match to protein family HMM PF06794 YP_002042715.1 identified by match to protein family HMM PF00485 YP_002042716.1 identified by match to protein family HMM PF02566 YP_002042717.1 complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons YP_002042718.1 identified by match to protein family HMM PF05976; match to protein family HMM TIGR01667 YP_002042719.1 'DapATase; bifunctional enzyme that functions in arginine and lysine biosynthetic pathways; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine or N-succinyl-2-L-amino-6-oxoheptanedioate from 2-oxoglutarate and N-succinyl-L-2,6-diaminoheptanedioate' YP_002042720.1 aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity YP_002042721.1 identified by match to protein family HMM PF02661 YP_002042722.1 identified by match to protein family HMM PF00160 YP_002042723.1 identified by match to protein family HMM PF07690 YP_002042725.1 identified by match to protein family HMM PF00070; match to protein family HMM PF01077; match to protein family HMM PF03460; match to protein family HMM PF04324; match to protein family HMM PF07992; match to protein family HMM TIGR02374 YP_002042726.1 'involved in reducing nitrite to ammonium to detoxify nitrite accumulation in anaerobic nitrate-respiring cells and regenerate NAD+; bounds to NirB, the cytoplasmic subunit, whose expression is induced at high nitrate concentrations' YP_002042728.1 member of the FNT family of formate and nitrite transporters YP_002042729.1 'multifunction enzyme consisting of uroporphyrin-III C-methyltransferase, precorrin-2 dehydrogenase and sirohydrochlorin ferrochelatase; catalyzes the methylation of uroporphyrinogen III to form precorrin-2, then catalyzes formation of sirohydrochlorin from precorrin-2 and finally catalyzed the formation of siroheme from sirohydrochlorin' YP_002042731.1 'catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002042732.1 catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate YP_002042733.1 catalyzes the interconversion of D-ribulose 5-phosphate to xylulose 5-phosphate YP_002042734.1 identified by match to protein family HMM PF02086; match to protein family HMM TIGR00571 YP_002042735.1 identified by match to protein family HMM PF05036 YP_002042736.1 catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate; functions in aromatic amino acid biosynthesis YP_002042737.1 type I enzyme similar to type II but differentially regulated; major shikimate kinase in fully repressed cells; catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis YP_002042738.1 outer membrane porin probably involved in uptake of extracellular double-stranded DNA; similar to outer membrane competence protein ComE from Haemophilus influenzae and outer membrane protein PilQ involved in type IV pilus production from Pseudomonas aeruginosa YP_002042741.1 identified by match to protein family HMM PF05137 YP_002042743.1 bifunctional murein transglycosylase/murein transpeptidase; penicillin-binding protein 1A; involved in the synthesis of cross-linked peptidoglycan from the lipid intermediates in cell wall formation; penicillin-insensitive transglycosylase catalyzes the formation of linear glycan strands and the penicillin-sensitive transpeptidase catalyzes the cross-linking of the peptide subunits YP_002042744.1 ADP-sugar pyrophosphatase; catalyzes the formation of D-ribose 5-phosphate from ADP-ribose; can also act on ADP-mannose and ADP-glucose YP_002042745.1 identified by match to protein family HMM PF07095 YP_002042746.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002042747.1 identified by match to protein family HMM PF01479 YP_002042748.1 'becomes active under oxidative stress; four conserved cysteines bind a zinc atom when they are in the reduced state and the enzyme is inactive; oxidative stress results in oxidized cysteines, release of zinc, and binding of Hsp33 to aggregation-prone proteins; forms dimers and higher order oligomers' YP_002042750.1 identified by glimmer YP_002042751.1 PEP carboxykinase; PEP carboxylase; PEPCK; catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP YP_002042752.1 membrane-localized osmosensor; histidine kinase; in high osmolarity EnvZ autophosphorylates itself and transfers phosphoryl group to OmpR YP_002042753.1 part of two-component system EnvZ/OmpR; regulates transcription of outer membrane porin genes ompC/F; under high osmolarity EnvZ functions as kinase/phosphotransferase and phosphorylates OmpR; the result is increased expression of ompC and repression of ompF; also functions in regulation of other genes; forms dimers upon phosphorylation YP_002042754.1 'necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites; arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus' YP_002042755.1 identified by match to protein family HMM PF00575; match to protein family HMM PF09371 YP_002042756.1 identified by match to protein family HMM PF04023 YP_002042757.1 cytoplasmic membrane ferrous uptake system permease; mutations disrupt the ability of Escherichia coli to take up ferrous iron; GTP-binding protein which requires GTP for efficient iron(II) uptake YP_002042758.1 identified by match to protein family HMM PF09012 YP_002042760.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002042761.1 Shows carboxylesterase activity with a preference for short chain fatty acid esters; involved in pimeloyl-CoA synthesis YP_002042762.1 involved in high-affinity gluconate transport YP_002042763.1 cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source YP_002042764.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002042765.1 amylomaltase; acts to release glucose from maltodextrins YP_002042766.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002042767.1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides YP_002042768.1 'represses the glpD, glpFK, glpTQ, and glpACB operons involved in glycerol-3-phosphate metabolism' YP_002042769.1 protease responsible for the cleavage between Ser and Asp residues of proteins in regions of high local hydrophilicity YP_002042770.1 belongs to rhodanese family; thiosulfate thiotransferase; in Escherichia coli this enzyme catalyzes the formation of thiocyanate from thiosulfate and cyanide with low efficiency; contains an active site cysteine YP_002042771.1 in Escherichia coli this homodimeric enzyme is expressed under aerobic conditions; anaerobic expression is repressed by the arcAB system; converts sn-glycerol-3-phosphate and ubiquinone-8 to dihydroxy acetone phosphate and ubiquinol-8; associates with the cytoplasmic membrane YP_002042774.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002042775.1 identified by match to protein family HMM PF07690 YP_002042776.1 identified by match to protein family HMM PF00920 YP_002042777.1 identified by match to protein family HMM PF00701 YP_002042778.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002042779.1 identified by match to protein family HMM PF00343; match to protein family HMM TIGR02093 YP_002042780.1 'catalyzes the formation of alpha-1,4-glucan chains from ADP-glucose' YP_002042781.1 catalyzes the formation of ADP-glucose and diphosphate from ATP and alpha-D-glucose 1-phosphate YP_002042782.1 'catalyzes the hydrolysis of the alpha-1,6-glucosidic linkages in partially depolymerized glycogen' YP_002042783.1 'catalyzes the transfer of a segment of a 1,4-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain' YP_002042784.1 catalyzes the formation of 4-aspartyl phosphate from aspartate 4-semialdehyde YP_002042785.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM TIGR00791 YP_002042786.1 thermoresistant; catalyzes the formation of 6-phospho-D-gluconate from gluconate YP_002042787.2 identified by match to protein family HMM PF00532 YP_002042788.1 identified by match to protein family HMM PF02678; match to protein family HMM PF07883 YP_002042789.1 identified by match to protein family HMM PF01408; match to protein family HMM PF02894 YP_002042790.1 YhhY; regulated by the fur regulator; unknown function YP_002042791.1 identified by glimmer YP_002042792.1 identified by match to protein family HMM PF00294; match to protein family HMM PF08220; match to protein family HMM PF08543 YP_002042793.1 identified by match to protein family HMM PF07090 YP_002042795.1 identified by match to protein family HMM PF02126 YP_002042796.1 periplasmic enzyme; post-translationally processed into two subunits which are required for wild-type enzyme activity; cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides YP_002042798.1 hydrolyzes diesters during transport at the inner face of the cytoplasmic membrane to glycerol-3-phosphate and alcohol; induced when cells are starved for inorganic phosphate YP_002042799.1 part of the UgpABCE glycerol-3-phosphate uptake system YP_002042800.1 with UgpABC is involved in uptake of glycerol-3-phosphate YP_002042801.1 with UgpEC is involved in the uptake of glycerol-3-phosphate YP_002042802.1 with UgpACE is involved in the uptake of glycerol-3-phosphate YP_002042803.1 identified by match to protein family HMM PF05012; match to protein family HMM TIGR01550 YP_002042804.1 identified by match to protein family HMM PF02604; match to protein family HMM TIGR01552 YP_002042805.1 'with LivGHMJ and LivGHMK is part of the high-affinity branched-chain amino acid transport system; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002042806.1 'Part of the ABC transporter complexes LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002042807.1 'Part of the ABC transporter complex LivFGHMJ and LivFGHMK involved in the high-affinity transport of branched-chain amino acids; LivFGHMK is specific for the transport of leucine, while LivFGHMJ is a transporter for leucine, isoleucine, and valine' YP_002042808.1 LivHMGF is the membrane component of the LIV-I/LS branched-chain amino acid transporter YP_002042809.1 identified by match to protein family HMM PF01094 YP_002042810.1 identified by match to protein family HMM PF00583 YP_002042812.1 identified by match to protein family HMM PF01094 YP_002042813.1 binds with the catalytic core of RNA polymerase to produce the holoenzyme; this sigma factor is responsible for the expression of heat shock promoters YP_002042814.1 'ABC transporter, membrane protein' YP_002042815.1 'ATP-binding protein of an ATP-binding cassette transporter; when bound to FtsX, FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions' YP_002042816.1 signal recognition protein receptor; functions in the targeting and insertion of membrane proteins YP_002042817.1 catalyzes the methylation of 16S rRNA at position G966 YP_002042818.1 identified by match to protein family HMM PF06611 YP_002042820.1 identified by match to protein family HMM PF07947 YP_002042821.1 'P-type ATPase involved in the export of lead, cadmium, zinc and mercury' YP_002042822.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002042823.1 identified by match to protein family HMM PF01206 YP_002042824.1 identified by match to protein family HMM PF02592; match to protein family HMM TIGR00697 YP_002042826.1 identified by match to protein family HMM PF07690 YP_002042827.1 identified by match to protein family HMM PF01594 YP_002042828.1 identified by match to protein family HMM PF01648 YP_002042829.1 Inhibits transcription at high concentrations of nickel YP_002042830.1 identified by match to protein family HMM PF01061 YP_002042831.1 identified by match to protein family HMM PF00005; match to protein family HMM PF01061 YP_002042832.1 identified by match to protein family HMM PF00529 YP_002042833.1 identified by glimmer YP_002042834.1 identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF03486; match to protein family HMM PF07992; match to protein family HMM TIGR00275 YP_002042835.1 identified by match to protein family HMM PF01384 YP_002042836.1 'ppGpp-dependent, membrane associated, stress protein produced under conditions of nutrient deprivation, osmotic shock and oxidative stress' YP_002042837.1 identified by match to protein family HMM PF00582 YP_002042838.1 member of the POT family of peptide transporters; probable proton-dependent peptide transporter function YP_002042839.1 predicted SAM-dependent methyltransferase YP_002042840.1 identified by match to protein family HMM PF01432 YP_002042843.1 identified by match to protein family HMM PF04378 YP_002042844.1 identified by glimmer YP_002042845.1 catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense YP_002042846.1 identified by match to protein family HMM PF00710; match to protein family HMM TIGR00520 YP_002042847.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002042848.1 identified by match to protein family HMM PF00294 YP_002042849.1 identified by match to protein family HMM PF01380 YP_002042850.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002042851.1 cytoplasmic; catalyzes the hydrolysis of trehalose to glucose YP_002042854.1 identified by match to protein family HMM PF00196; match to protein family HMM PF01726; match to protein family HMM PF08281 YP_002042855.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002042856.1 identified by match to protein family HMM PF03631; match to protein family HMM TIGR00766 YP_002042857.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00883 YP_002042858.1 identified by match to protein family HMM PF05170 YP_002042859.1 in Escherichia coli this protein is involved in flagellar function YP_002042860.1 identified by match to protein family HMM PF00675; match to protein family HMM PF05193 YP_002042861.1 involved in the transport of C4-dicarboxylates across the membrane YP_002042862.1 HmsP in Yersinia pestis plays a role in invasion of epithelial cells; the EAL-domain portion of HmsP from Y. pestis shows phosphodiesterase activity which is required for the inhibition of biofilm formation; inner membrane protein; similar to a phosphodiesterase protein from E. coli YP_002042863.1 'cellulose is produced by the multicellular morphotypes of E. coli and Salmonella typhimurium; the cellulose biosynthesis genes bcsA, bcsB, bcsZ and bcsC are constitutively transcribed, however, cellulose synthesis is dependent on the expression of adrA' YP_002042864.1 'catalyzes the hydrolysis of 1,4-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans' YP_002042865.1 'binds the cellulose synthase activator, bis-(3'-5') cyclic diguanylic acid (c-di-GMP)' YP_002042866.1 'polymerizes uridine 5'-diphosphate glucose to cellulose; acts with BcsB, BcsZ and BcsC in cellulose biosynthesis' YP_002042867.1 identified by match to protein family HMM PF06564; match to protein family HMM TIGR03371 YP_002042870.2 identified by match to protein family HMM TIGR03369 YP_002042871.1 identified by match to protein family HMM TIGR03493 YP_002042872.1 identified by match to protein family HMM TIGR03368 YP_002042875.1 Part of the ABC transporter complex DppABCDF involved in the transport of dipeptides YP_002042876.1 DppD and DppF are the ATP-binding components of the ABC dipeptide transport system DppABCDF YP_002042877.1 identified by match to protein family HMM PF00528 YP_002042878.1 transports peptides consisting of two or three amino acids YP_002042879.1 identified by match to protein family HMM PF00496 YP_002042880.1 identified by match to protein family HMM PF00860 YP_002042882.1 identified by glimmer YP_002042883.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002042884.1 catalyzes the addition of a phosphoethanolamine group to the outer Kdo residue of lipopolysaccharide YP_002042885.1 identified by match to protein family HMM PF00419 YP_002042886.1 identified by match to protein family HMM PF00577 YP_002042887.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002042888.1 identified by match to protein family HMM PF00419 YP_002042889.1 identified by glimmer YP_002042891.1 'constitutive, catalyzes the hydrolysis of alkylated DNA, releasing 3-methyladenine' YP_002042892.1 identified by match to protein family HMM PF00583 YP_002042893.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509 YP_002042894.1 identified by match to protein family HMM PF00691; match to protein family HMM PF05433 YP_002042895.1 identified by match to protein family HMM PF00389; match to protein family HMM PF02826 YP_002042897.1 identified by glimmer YP_002042899.1 identified by match to protein family HMM PF00313 YP_002042901.1 glycine--tRNA ligase beta chain; glyS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002042902.1 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002042905.1 identified by match to protein family HMM PF01757 YP_002042906.1 identified by match to protein family HMM PF05360 YP_002042907.1 identified by glimmer YP_002042908.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782; match to protein family HMM TIGR01312 YP_002042909.1 catalyzes the interconversion of D-xylose to D-xylulose YP_002042910.1 identified by match to protein family HMM PF00165 YP_002042911.1 identified by match to protein family HMM PF01832 YP_002042912.1 'periplasmic enzyme that degrades maltodextrins that enter via the outer membrane porin LamB; hydrolyzes alpha-(1,4) glycosidic linkages; contains internal disulfide bonds' YP_002042913.1 'transaminase C; catalyzes transamination of alanine, valine, and 2-aminobutyrate with their respective 2-keto acids; also catalyzes terminal step in valine biosynthesis' YP_002042914.1 identified by match to protein family HMM PF00037 YP_002042915.1 identified by match to protein family HMM PF01614; match to protein family HMM PF09339 YP_002042916.1 'NAD(P)H-dependent; catalyzes the reduction of 2,3-diketo-L-gulonate to 3-keto-L-gulonate' YP_002042917.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002042919.1 'membrane-spanning protein involved in uptake of 2,3-diketo-L-gulonate; part of the tri-partite ATP-independent periplasmic transport system (TRAP) YiaMNO' YP_002042920.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_002042921.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_002042922.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002042923.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate YP_002042924.1 'L-xylulose 5-phosphate 3-epimerase activity not yet demonstrated; may be involved in the utilization of 2,3-diketo-L-gulonate' YP_002042925.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002042926.1 identified by match to protein family HMM PF00165 YP_002042927.1 identified by match to protein family HMM PF07944 YP_002042928.1 identified by match to protein family HMM PF00171 YP_002042929.1 identified by match to protein family HMM PF00480 YP_002042930.1 identified by match to protein family HMM PF00009; match to protein family HMM PF03144; match to protein family HMM PF09106; match to protein family HMM PF09107; match to protein family HMM TIGR00475 YP_002042931.1 catalyzes the formation of selenocysteinyl-tRNA(Sec) from seryl-tRNA(Sec) and L-selenophosphate in selenoprotein biosynthesis YP_002042932.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002042933.1 identified by match to protein family HMM PF00359; match to protein family HMM PF02302; match to protein family HMM PF02378; match to protein family HMM TIGR00851 YP_002042934.1 identified by match to protein family HMM PF01232; match to protein family HMM PF08125 YP_002042935.1 Acts as a repressor of the mtlAD operon YP_002042938.1 identified by glimmer YP_002042940.1 identified by match to protein family HMM PF03895; match to protein family HMM PF05658; match to protein family HMM PF05662 YP_002042941.1 identified by match to protein family HMM PF02652; match to protein family HMM TIGR00795 YP_002042942.1 represses the lctPRD operon YP_002042943.1 flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration YP_002042944.1 member of the SPOUT superfamily of RNA methyltransferases; no methyltransferase activity observed with certain tRNA substrates YP_002042945.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002042946.1 identified by glimmer YP_002042947.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002042948.1 identified by match to protein family HMM PF07690 YP_002042949.1 catalyzes the O-acetylation of serine YP_002042950.1 catalyzes the NAD(P)H-dependent reduction of glycerol 3-phosphate to glycerone phosphate YP_002042951.1 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA YP_002042952.1 identified by match to protein family HMM PF00462; match to protein family HMM TIGR02181 YP_002042953.1 identified by match to protein family HMM PF00581 YP_002042954.1 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate YP_002042955.1 identified by match to protein family HMM PF01551 YP_002042956.1 identified by match to protein family HMM PF04748 YP_002042957.1 identified by match to protein family HMM PF00535 YP_002042958.1 'converts threonine and NAD to 1,2-amino-3-oxobutanoate and NADH; functions in threonine catabolism' YP_002042959.1 catalyzes the formation of 2-amino-3-oxobutanoate from acetyl-CoA and glycine YP_002042960.1 catalyzes the interconversion between ADP-D-glycero-beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose YP_002042961.1 catalyzes the transfer of the second heptose to the heptosyl-KDO2 moiety of the lipopolysaccharide inner core YP_002042962.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02193 YP_002042963.1 identified by match to protein family HMM PF04932 YP_002042964.1 identified by match to protein family HMM PF00534 YP_002042966.1 identified by match to protein family HMM PF06176 YP_002042967.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002042968.1 identified by match to protein family HMM PF01501; match to protein family HMM PF08437 YP_002042969.1 identified by match to protein family HMM PF00534 YP_002042970.1 identified by match to protein family HMM PF01501 YP_002042971.1 identified by match to protein family HMM PF06293 YP_002042972.1 identified by match to protein family HMM PF00534 YP_002042973.1 identified by match to protein family HMM PF01075; match to protein family HMM TIGR02201 YP_002042974.1 catalyzes the transfer of 2-keto-3-deoxy-D-manno-octulosonic acid to lipid A YP_002042975.1 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA YP_002042976.1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases YP_002042977.1 'in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif' YP_002042978.1 required for 70S ribosome assembly YP_002042979.1 Involved in DNA double-strand break repair and recombination. Promotes the annealing of complementary single-stranded DNA and by simulation of RAD51 recombinase YP_002042980.1 catalyzes the formation of dUMP from dUTP YP_002042981.1 FtsZ binding protein; synthetically lethal with a defect in the Min system; this protein is the first identified nucleoid occlusion factor which works along with the Min system to properly position the FtsZ ring assembly YP_002042982.1 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate YP_002042983.1 RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs YP_002042984.1 identified by match to protein family HMM PF03755; match to protein family HMM PF08340; match to protein family HMM TIGR00255 YP_002042985.1 identified by match to protein family HMM PF00126 YP_002042986.1 identified by match to protein family HMM PF00753 YP_002042987.1 identified by match to protein family HMM PF03458 YP_002042988.1 this ligase is similar to LigA but it lacks the C-terminal BRCT domain; catalyzes strand joining of nicked DNA in the presence of a divalent cation and NAD+ YP_002042989.1 'Essential for recycling GMP and indirectly, cGMP' YP_002042990.1 promotes RNA polymerase assembly or stability; latches the N- and C-terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits YP_002042991.1 identified by match to protein family HMM PF01966; match to protein family HMM PF02824; match to protein family HMM PF04607; match to protein family HMM TIGR00691 YP_002042992.1 specifically modifies tRNA at position G18 YP_002042993.1 catalyzes branch migration in Holliday junction intermediates YP_002042995.1 identified by match to protein family HMM PF03616; match to protein family HMM TIGR00210 YP_002042996.1 identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801 YP_002042997.1 identified by match to protein family HMM PF05170 YP_002042998.1 'catalyzes the transfer of alpha-xylosyl residue from alpha-xyloside to xylose, glucose, mannose, fructose, maltose, isomaltose, nigerose, kojibiose, sucrose, and trehalose; shows higher activity against alpha-xylosyl fluoride, isoprimeverose (6-O-alpha-xylopyranosyl-glucopyranose), and alpha-xyloside in xyloglucan oligosaccharides' YP_002042999.1 may be involved in the transport of galactosides-pentoses-hexuronides YP_002043004.1 identified by match to protein family HMM PF00486 YP_002043005.1 identified by glimmer YP_002043006.1 identified by match to protein family HMM PF00857 YP_002043008.1 identified by match to protein family HMM PF00122; match to protein family HMM PF00690; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01524 YP_002043010.1 identified by match to protein family HMM PF02308 YP_002043011.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00950 YP_002043012.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002043013.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002043014.1 identified by match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002043015.1 identified by match to protein family HMM PF03613 YP_002043016.1 identified by match to protein family HMM PF03609 YP_002043017.1 identified by match to protein family HMM PF03830 YP_002043018.1 identified by match to protein family HMM PF03610 YP_002043019.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874; match to protein family HMM PF07728 YP_002043021.1 identified by glimmer YP_002043022.1 identified by match to protein family HMM PF00232 YP_002043023.1 identified by match to protein family HMM PF06296 YP_002043024.1 identified by match to protein family HMM PF01381 YP_002043026.1 identified by match to protein family HMM PF00381; match to protein family HMM TIGR01003 YP_002043027.1 'class II aldolase; catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis' YP_002043028.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002043029.1 identified by match to protein family HMM PF03611 YP_002043031.1 identified by match to protein family HMM PF00359 YP_002043032.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002043033.1 identified by match to protein family HMM PF06711 YP_002043034.1 cytoplasmic membrane protein that functions as a monomer; catalyzes the active transport of sugar-phosphates such as glucose-6-phosphate with the obligatory exchange of inorganic phosphate or organophosphate YP_002043035.1 membrane protein regulates uhpT expression YP_002043036.1 Member of the two-component regulatory system UhpB/UhpA involved in the regulation of the uptake of hexose ph YP_002043037.1 'response regulator in two-component regulatory system wtih UhpB; phosphorylated UhpA is a positive activator uhpT, a hexose phosphates transporter' YP_002043039.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00885 YP_002043040.1 identified by match to protein family HMM PF00294; match to protein family HMM TIGR02152 YP_002043041.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220 YP_002043042.1 'with IlvB catalyzes the formation of 2-acetolactate from pyruvate, the small subunit is required for full activity and valine sensitivity; E.coli produces 3 isoenzymes of acetolactate synthase which differ in specificity to substrates, valine sensitivity and affinity for cofactors; also known as acetolactate synthase small subunit' YP_002043043.1 identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118 YP_002043044.1 identified by match to protein family HMM PF00892 YP_002043045.1 multidrug efflux protein involved in adaptation to low energy shock YP_002043046.1 regulates the synthesis and expression of the dsdXA operon and dadA gene YP_002043047.1 member of the Gnt family of gluconate transporters; not involved in gluconate transport; unknown function YP_002043048.1 catalyzes the formation of pyruvate from serine YP_002043049.1 identified by glimmer YP_002043052.1 identified by match to protein family HMM PF02656 YP_002043053.1 identified by glimmer YP_002043054.1 identified by glimmer YP_002043055.1 identified by match to protein family HMM PF02080; match to protein family HMM PF06826; match to protein family HMM TIGR01625 YP_002043056.1 '16 kDa heat shock protein B; associates with aggregated proteins, together with ibpA, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress; ATP-independent' YP_002043057.1 with IbpB associates with aggregated proteins to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress YP_002043059.1 identified by match to protein family HMM PF07119 YP_002043060.1 identified by match to protein family HMM PF03918 YP_002043061.1 identified by match to protein family HMM PF00578; match to protein family HMM PF08534; match to protein family HMM TIGR00385 YP_002043062.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR00353 YP_002043063.1 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome c maturation system; periplasmic protein anchored to the inner membrane YP_002043064.1 identified by match to protein family HMM PF04995; match to protein family HMM TIGR03141 YP_002043065.1 identified by match to protein family HMM PF01578; match to protein family HMM TIGR01191 YP_002043066.1 identified by match to protein family HMM PF03379; match to protein family HMM TIGR01190 YP_002043067.1 ATP-binding protein; required for proper cytochrome c maturation YP_002043068.1 identified by match to protein family HMM PF03150 YP_002043069.1 'TorD; involved in the biogenesis of torA; acts on torA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor' YP_002043070.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM TIGR00509; match to protein family HMM TIGR01409; match to protein family HMM TIGR02164 YP_002043071.1 identified by match to protein family HMM PF03264; match to protein family HMM TIGR02162 YP_002043072.1 response regulator in two-component regulatory system with TorS; involved in regulation of trimethylamine N-oxide reductase genes YP_002043073.1 periplasmic sensory protein associated with the TorRS two-component regulatory system YP_002043075.1 Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide YP_002043076.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM TIGR00881; match to protein family HMM TIGR00893 YP_002043077.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002043078.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and pyruvate from 2-dehydro-3-deoxy-D-galactonate 6-phosphate; functions in galactonate metabolism YP_002043079.1 identified by match to protein family HMM PF05035 YP_002043080.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002043081.1 'YidA; catalyzes the dephosphorylation of erythrose 4-phosphate (preferred substrate), mannose 1-phosphate and p-nitrophenyl phosphate; hydrolyzes the alpha-D-glucose-1-phosphate but not the beta form; member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins' YP_002043082.1 identified by match to protein family HMM PF07690 YP_002043083.1 identified by match to protein family HMM PF01188; match to protein family HMM PF02746 YP_002043084.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002043085.1 negatively supercoils closed circular double-stranded DNA YP_002043086.1 'Required for DNA replication; binds preferentially to single-stranded, linear DNA' YP_002043087.1 binds the polymerase to DNA and acts as a sliding clamp YP_002043088.1 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself. YP_002043089.1 in Escherichia coli transcription of this gene is enhanced by polyamines YP_002043090.1 protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus; this enzyme also cleaves other RNA substrates YP_002043091.1 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria YP_002043092.1 'in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE' YP_002043093.1 Confers resistance to chloramphenicol YP_002043094.1 Involved in anaerobic NO protection YP_002043096.1 identified by match to protein family HMM PF03358 YP_002043097.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002043098.1 'YieH; catalyzes the dephosphorylation of phosphoenolpyruvate, AMP and p-nitrophenyl phosphate; purine and pyrimidine nucleotides are secondary substrates; member of the haloacid dehalogenase-like hydrolases superfamily' YP_002043099.1 regulates several genes involved in high affinity phosphate uptake; under conditions of high phosphate concentrations downregulates the PHO regulon YP_002043100.1 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation YP_002043101.1 Part of the ABC transporter complex PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002043102.1 part of the ATP-dependent phosphate uptake system PstABCS responsible for inorganic phosphate (Pi) uptake under Pi starvation conditions YP_002043103.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00975 YP_002043104.1 identified by match to protein family HMM PF02378; match to protein family HMM PF02379; match to protein family HMM TIGR00829; match to protein family HMM TIGR01427 YP_002043105.1 catalyzes the conversion of shikimate to 3-dehydroshikimate YP_002043106.1 identified by match to protein family HMM PF00496 YP_002043107.1 'Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source' YP_002043108.1 forms a homotrimer; catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc; function in cell wall synthesis YP_002043110.1 part of catalytic core of ATP synthase; alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in producing ATP from ADP in the presence of the proton motive force across the membrane YP_002043111.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The beta chain is a regulatory subunit YP_002043112.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit YP_002043113.1 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit YP_002043114.1 Produces ATP from ADP in the presence of a proton gradient across the membrane; the delta subunit is part of the catalytic core of the ATP synthase complex YP_002043115.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit B is part of the membrane proton channel. YP_002043116.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 YP_002043117.1 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 YP_002043118.2 identified by match to protein family HMM PF03899 YP_002043120.1 identified by glimmer YP_002043121.1 glucose-inhibited division protein B; SAM-dependent methyltransferase; methylates the N7 position of guanosine in position 527 of 16S rRNA YP_002043122.1 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs YP_002043123.1 'An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group' YP_002043124.1 transcriptional repressor of asnA which codes for aspartate-ammonia ligase YP_002043125.1 catalyzes the formation of asparagine from aspartate and ammonia YP_002043126.1 contains a von Willibrand factor type A domain; stimulates the ATPase activity of RavA YP_002043127.1 'interacts with LdcI, lysine decarboxylase; may be active in late log/ early stationary phase' YP_002043128.1 Responsible for the low-affinity transport of potassium into the cell; involved in potassium ion uptake under hyper-osmotic stress at a low pH YP_002043129.1 cytoplasmic mutarotase that catalyzes the conversion between beta-pyran and beta-furan forms of D-ribose; RbsD is required for efficient ribose utilization in E. coli; rbsD-mutant E. coli strains are unable to use ribose as a sole carbon source YP_002043130.1 with RbsBCD acts to import ribose into the cell; RbsA contains 2 ATP-binding domain YP_002043131.1 functions to transport ribose at high affinity; forms a complex with RbsA2C2B YP_002043132.1 periplasmic substrate-binding component of the ATP-dependent ribose transport system YP_002043133.1 catalyzes the formation of D-ribose 5-phosphate from ribose YP_002043134.1 DNA-binding transcriptional repressor of ribose metabolism YP_002043135.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00711 YP_002043136.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07729 YP_002043137.1 Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon YP_002043138.1 identified by match to protein family HMM PF04219 YP_002043139.1 'among the AAA+ ATPases, the YifB protease family belongs to the Helix 2 insert clade; unknown function' YP_002043140.1 catalyzes the formation of 2-acetolactate from pyruvate; also known as acetolactate synthase large subunit YP_002043142.1 catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids YP_002043143.1 'catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis' YP_002043144.1 'threonine deaminase; threonine dehydratase; in Escherichia coli, IlvA is part of the isoleucine biosynthetic pathway' YP_002043145.1 identified by match to protein family HMM PF05973 YP_002043147.1 participates in controlling several genes involved in isoleucine and valine biosynthesis; activates the transcription of the ilvC gene in the presence of acetolactate or acetohydroxybutyrate YP_002043148.1 'catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis' YP_002043149.1 identified by match to protein family HMM PF00639 YP_002043150.1 single-stranded DNA-dependent ATPase; initiates unwinding at a nick in the DNA; involved in DNA replication YP_002043151.1 'catalyzes the conversion of guanosine 5'-triphosphate,3'-diphosphate (pppGpp) to guanosine 5'-diphosphate,3'-diphosphate (ppGpp); pppGpp and ppGpp control the stringent response during amino acid starvation' YP_002043152.1 'enables ATP-dependent unwinding of double stranded RNA as a component of the RNA degradosome, a multi-enzyme complex important in RNA processing and messenger RNA degradation' YP_002043153.1 identified by match to protein family HMM PF00085; match to protein family HMM TIGR01068 YP_002043154.1 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes YP_002043155.1 identified by match to protein family HMM PF00953; match to protein family HMM TIGR02380 YP_002043156.1 Enterobacterial Common Antigen (ECA) polysaccharide chain length modulation protein YP_002043157.1 identified by match to protein family HMM PF02350; match to protein family HMM TIGR00236 YP_002043158.1 catalyzes the oxidation of UDP-N-acetyl-D-mannosamine to UDP-N-acetylmannosaminuronic acid YP_002043159.1 identified by match to protein family HMM PF00106; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02719; match to protein family HMM PF04321; match to protein family HMM PF07993; match to protein family HMM TIGR01181 YP_002043161.1 identified by match to protein family HMM PF00583; match to protein family HMM TIGR02382 YP_002043162.1 catalyzes the formation of dTDP-D-fucosamine from dTDP-4-oxo-6-deoxy-D-glucose in enterobacterial common antigen biosynthesis YP_002043163.1 identified by match to protein family HMM PF01943 YP_002043164.1 catalyzes the synthesis of a lipid-linked intermediate involved in ECA synthesis YP_002043165.1 enterobacterial common antigen polymerase YP_002043166.1 identified by match to protein family HMM PF03808; match to protein family HMM TIGR00696 YP_002043167.1 uncharacterized member of the amino acid-polyamine-organocation (APC) superfamily of amino acid transporters; unknown function YP_002043168.1 identified by glimmer YP_002043169.1 identified by match to protein family HMM PF07219; match to protein family HMM PF07719; match to protein family HMM TIGR00540 YP_002043170.1 identified by match to protein family HMM PF04375 YP_002043171.1 catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane; functions in tetrapyrrole and heme biosynthesis YP_002043172.1 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis YP_002043173.1 catalyzes transfer of adenylyl group of ATP from pyrophosphate to the 3'-hydroxyl group to form cyclic AMP YP_002043174.1 defects in the mitochondrial frataxin protein cause Friedreich ataxis which is an autosomal recessive neurodegenerative disease; based on phylogenomic distribution this protein may have a role in iron-sulfur cluster protein assembly YP_002043177.1 involved in lysine biosynthesis; DAP epimerase; produces DL-diaminopimelate from LL-diaminopimelate YP_002043178.1 identified by match to protein family HMM PF04340 YP_002043179.1 site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs YP_002043180.1 YigB; member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein; unknown function YP_002043181.1 unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. YP_002043182.1 responsible for the influx of magnesium ions YP_002043185.1 identified by match to protein family HMM PF00892; match to protein family HMM TIGR00688 YP_002043186.1 identified by match to protein family HMM PF03061; match to protein family HMM TIGR00369 YP_002043187.1 catalyzes the hydrolysis of phosphatidylcholine YP_002043188.1 'functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway' YP_002043189.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002043190.1 identified by match to protein family HMM PF01810; match to protein family HMM TIGR00949 YP_002043191.1 lecithinase B; catalyzes the conversion of 1-lysophosphatidylcholine to glycerophosphocholine; can also hydrolyze 2-acyl glycerophosphoethanolamine and other substrates YP_002043192.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002043193.1 catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine to form methionine YP_002043194.1 identified by glimmer YP_002043195.1 identified by match to protein family HMM PF02810; match to protein family HMM PF04055 YP_002043196.2 identified by match to protein family HMM PF01738 YP_002043197.1 catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate; involved in the pyrimidine salvage pathway YP_002043198.1 YigN; nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence; transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner YP_002043199.1 Catalyzes the carbon methylation reaction in the biosynthesis of ubiquinone YP_002043200.1 identified by match to protein family HMM PF02036 YP_002043201.1 an Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions YP_002043202.1 TatA; similar to TatE that is found in some proteobacteria; part of system that translocates proteins with a conserved twin arginine motif across the inner membrane; capable of translocating folded substrates typically those with bound cofactors; similar to a protein import system in thylakoid membranes YP_002043203.1 mediates the export of protein precursors bearing twin-arginine signal peptides YP_002043204.1 with TatABE forms the twin-arginine translocation complex which is involved in the transport of proteins across the cytoplasmic membrane YP_002043205.1 magnesium dependent; not involved in the Sec-independent protein export system YP_002043206.1 identified by match to protein family HMM PF02357; match to protein family HMM TIGR01955 YP_002043207.1 catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol YP_002043208.1 NAD(P)H-flavin reductase; catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide; in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin YP_002043209.1 identified by match to protein family HMM PF05935 YP_002043210.1 FadA; fatty acid oxidation complex component beta; functions in a heterotetramer with FadB; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids YP_002043211.1 'includes enoyl-CoA hydratase, delta(3)-cis-delta(2)-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, and 3-hydroxybutyryl-CoA epimerase; catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA; also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; forms a heterotetramer with FadA; similar to FadI2J2 complex; functions in beta-oxidation of fatty acids' YP_002043212.1 catalyzes the hydrolysis of dipeptides with a proline at the C-terminal; also catalyzes the low efficiency hydrolysis of organophosphate di- and tri-esters YP_002043213.1 identified by match to protein family HMM PF01205; match to protein family HMM PF09186; match to protein family HMM TIGR00257 YP_002043214.1 identified by match to protein family HMM PF02386; match to protein family HMM TIGR00933 YP_002043215.1 catalyzes the oxidation of protoporphyrinogen IX to form protoporphyrin IX YP_002043216.1 in Escherichia coli the MobB protein is not essential but has been found to interact with multiple proteins involved in the molybdopterin guanine dinucleotide cofactor biosynthesis pathway YP_002043217.1 in Escherichia coli MobA links a guanosine 5'-phosphate to molydopterin to form molybdopterin guanine dinucleotide during molybdenum cofactor biosynthesis YP_002043218.1 identified by match to protein family HMM PF06288 YP_002043219.1 catalyzes the phosphorylation of protein substrates at serine and threonine residues in vitro; specific substrate in vivo has not been identified yet; plays a role in long-term cell survival and expression of surface appendages YP_002043220.1 identified by match to protein family HMM PF01323 YP_002043221.1 identified by match to protein family HMM PF01553 YP_002043222.1 identified by glimmer YP_002043223.1 'has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair' YP_002043224.1 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential YP_002043225.1 identified by match to protein family HMM PF04220 YP_002043226.1 catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III YP_002043227.1 response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes; interacts with sigma-54 YP_002043228.1 sensory histidine kinase in two-component regulatory system with GlnG; acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC by phosphorylation/dephosphorylation YP_002043229.1 forms a homododecamer; forms glutamine from ammonia and glutamate with the conversion of ATP to ADP and phosphate; also functions in the assimilation of ammonia; highly regulated protein controlled by the addition/removal of adenylyl groups by adenylyltransferase from specific tyrosine residues; addition of adenylyl groups results in inactivation of the enzyme YP_002043230.1 identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM TIGR00231; match to protein family HMM TIGR01394 YP_002043232.1 porin involved in the transport of small molecular weight solutes (up to 600 Daltons) across the cell wall; specific substrate still unknown YP_002043233.1 identified by match to protein family HMM TIGR00792 YP_002043234.1 identified by match to protein family HMM TIGR00792 YP_002043235.1 identified by match to protein family HMM PF01055 YP_002043236.1 identified by match to protein family HMM PF01925 YP_002043237.1 identified by match to protein family HMM PF01263 YP_002043238.1 identified by match to protein family HMM PF07221 YP_002043239.1 identified by match to protein family HMM PF01791 YP_002043240.1 identified by match to protein family HMM PF03446 YP_002043241.1 identified by glimmer YP_002043242.1 identified by match to protein family HMM PF00294 YP_002043243.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002043244.1 identified by match to protein family HMM PF00702; match to protein family HMM TIGR01509 YP_002043245.1 RNase BN; required for 3' maturation of certain phage T4-encoded tRNAs; forms a dimer; specific for immature tRNA substrates containing incorrect residues within the universal CCA sequence; 3' to 5' exoribonuclease YP_002043246.1 hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr); possible defense mechanism against a harmful effect of D-tyrosine YP_002043247.1 identified by match to protein family HMM PF00583; match to protein family HMM PF09500; match to protein family HMM TIGR02447 YP_002043248.1 identified by match to protein family HMM PF01381 YP_002043250.1 identified by match to protein family HMM PF07859 YP_002043253.1 identified by match to protein family HMM PF01381 YP_002043254.1 required for the formation of active formate dehydrogenase YP_002043255.1 cytochrome b556(FDO) component; heme containing YP_002043256.1 identified by match to protein family HMM PF00037; match to protein family HMM PF09163; match to protein family HMM TIGR01582 YP_002043257.1 involved in the production or activity of formate dehydrogenase-H which is active when nitrate is not present during anaerobic growth YP_002043260.1 identified by glimmer YP_002043261.1 identified by match to protein family HMM PF05437 YP_002043262.1 identified by match to protein family HMM PF03591 YP_002043263.1 identified by match to protein family HMM PF01381; match to protein family HMM PF07883 YP_002043264.1 identified by match to protein family HMM PF05336; match to protein family HMM TIGR02625 YP_002043265.1 identified by match to protein family HMM PF00465; match to protein family HMM TIGR02638 YP_002043266.1 identified by match to protein family HMM PF00596; match to protein family HMM TIGR02624 YP_002043267.1 catalyzes the formation of L-rhamnulose from L-rhamnose YP_002043268.1 catalyzes the ATP-dependent phosphorylation of rhamnulose YP_002043269.1 activates the expression of the rhaBAD operon and rhaT gene YP_002043270.1 activates the expression of rhaRS in response to L-rhamnose YP_002043271.1 transports L-rhamnose and L-lyxose into the cell YP_002043274.1 identified by glimmer YP_002043275.1 identified by match to protein family HMM PF06178 YP_002043276.1 identified by match to protein family HMM PF06808; match to protein family HMM TIGR00786 YP_002043277.1 identified by match to protein family HMM PF04290 YP_002043278.1 identified by match to protein family HMM PF03480; match to protein family HMM TIGR00787 YP_002043279.1 SodA; manganese binding; only present under aerobic conditions; destroys free radicals YP_002043280.1 identified by match to protein family HMM PF03473; match to protein family HMM PF03475 YP_002043282.1 identified by glimmer YP_002043283.1 part of two-component CpxA/CpxR system; senses envelope stress; upregulates a number of periplasmic folding and trafficking factors YP_002043284.1 response regulator in two-component regulatory system with CpxA; part of the envelope stress response system YP_002043285.1 repressor of the Cpx envelope stress response pathway which occurs via periplasmic interactions with CpxA; CpxP is degraded by DegP protease especially in the presence of misfolded substrates YP_002043286.1 identified by match to protein family HMM PF00589 YP_002043291.1 identified by glimmer YP_002043293.1 identified by match to protein family HMM PF05840 YP_002043294.1 identified by match to protein family HMM PF02661 YP_002043296.1 identified by glimmer YP_002043297.1 identified by glimmer YP_002043298.1 identified by glimmer YP_002043299.1 identified by match to protein family HMM PF04860; match to protein family HMM TIGR01540 YP_002043300.1 identified by match to protein family HMM PF03237; match to protein family HMM PF06056 YP_002043301.1 identified by match to protein family HMM PF05929 YP_002043302.1 identified by match to protein family HMM PF05125; match to protein family HMM TIGR01551 YP_002043303.1 identified by match to protein family HMM PF05944; match to protein family HMM PF07719 YP_002043304.1 identified by glimmer YP_002043305.1 identified by match to protein family HMM PF05926 YP_002043306.1 identified by match to protein family HMM PF05489 YP_002043308.1 identified by match to protein family HMM PF00959 YP_002043309.1 identified by match to protein family HMM TIGR03495 YP_002043310.1 identified by match to protein family HMM PF06891 YP_002043311.1 identified by match to protein family HMM PF05069; match to protein family HMM TIGR01635 YP_002043313.1 identified by match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_002043314.1 identified by match to protein family HMM PF04965 YP_002043315.1 identified by match to protein family HMM PF04865 YP_002043316.1 identified by match to protein family HMM PF09684; match to protein family HMM TIGR01634 YP_002043317.1 identified by match to protein family HMM PF03406; match to protein family HMM PF07484 YP_002043318.1 identified by match to protein family HMM PF02413 YP_002043319.1 identified by match to protein family HMM PF04984 YP_002043320.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_002043321.1 identified by match to protein family HMM TIGR01760 YP_002043322.1 identified by match to protein family HMM PF06995 YP_002043323.1 identified by match to protein family HMM PF05954 YP_002043324.1 'member of cation diffusion facilitator family; CDF; membrane-bound; induced by both zinc and iron, but does not induce resistance to zinc; can transport zinc(II) in a proton-dependent manner; instead this protein induces iron resistance; forms dimers' YP_002043325.1 'catalyzes the formation of D-fructose 1,6-bisphosphate from D-fructose 6-phosphate in glycolysis' YP_002043326.1 identified by match to protein family HMM PF01547; match to protein family HMM TIGR00971 YP_002043327.1 identified by match to protein family HMM PF07690; match to protein family HMM TIGR00792 YP_002043328.1 phosphorylates aminoimidazole ribotide (AIR) which forms 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate (HMP-P); synthesis of HMP-P from AIR is complex and requires the product of thiC gene at least YP_002043329.1 identified by match to protein family HMM PF03747 YP_002043330.1 identified by match to protein family HMM PF00392; match to protein family HMM PF07702 YP_002043332.1 identified by match to protein family HMM PF07883 YP_002043333.1 identified by match to protein family HMM PF00370; match to protein family HMM PF02782 YP_002043334.1 identified by match to protein family HMM PF04198 YP_002043335.1 identified by glimmer YP_002043336.1 identified by match to protein family HMM PF00005 YP_002043337.1 identified by match to protein family HMM PF02653 YP_002043338.1 identified by match to protein family HMM PF02653 YP_002043340.1 identified by match to protein family HMM PF01791 YP_002043341.1 identified by match to protein family HMM PF03992 YP_002043342.1 identified by match to protein family HMM PF00834 YP_002043343.1 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate YP_002043344.1 identified by match to protein family HMM PF07305 YP_002043345.1 identified by match to protein family HMM PF05656 YP_002043346.1 identified by match to protein family HMM PF00175; match to protein family HMM PF00970 YP_002043347.1 'type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese' YP_002043348.1 Converts glycerol and ADP to glycerol-3-phosphate and ADP YP_002043349.1 identified by match to protein family HMM PF00230; match to protein family HMM TIGR00861 YP_002043350.1 identified by match to protein family HMM PF06005 YP_002043351.1 identified by glimmer YP_002043352.1 regulator of RNase E; increases half-life and abundance of RNAs; interacts with RNase E possibly inhibiting catalytic activity YP_002043353.1 'catalyzes the formation of dimethylmenaquinone from 1,4-dihydroxy-2-naphthoate and octaprenyl diphosphate' YP_002043354.1 heat shock protein involved in degradation of misfolded proteins YP_002043355.1 heat shock protein involved in degradation of misfolded proteins YP_002043356.1 identified by match to protein family HMM PF05036; match to protein family HMM TIGR02223 YP_002043357.1 'negatively controls the transcription initiation of genes such as deoCABD, udp, and cdd encoding catabolizing enzymes and nupC, nupG, and tsx encoding transporting and pore-forming proteins' YP_002043358.1 'binding of PriA to forked DNA starts the assembly of the primosome, also possesses 3'-5' helicase activity' YP_002043359.1 'RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome' YP_002043360.1 identified by match to protein family HMM PF09601; match to protein family HMM TIGR02117 YP_002043361.1 identified by match to protein family HMM PF05935 YP_002043363.1 when combined with S-adenosylmethionine represses the expression of the methionine regulon and of proteins involved in S-adenosylmethionine synthesis YP_002043364.1 catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine YP_002043365.1 multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways YP_002043366.1 identified by match to protein family HMM PF00924; match to protein family HMM PF05552 YP_002043369.1 identified by match to protein family HMM PF00149; match to protein family HMM PF02872 YP_002043370.1 'MTHFR; catalyzes NADH-linked reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor' YP_002043371.1 identified by match to protein family HMM PF00141; match to protein family HMM TIGR00198 YP_002043372.1 identified by match to protein family HMM PF06940 YP_002043373.1 forms dimers and octamers; involved in conversion of glycerol to dihydroxy-acetone YP_002043374.1 similar to transaldolase from Escherichia coli; many organisms have multiple copies YP_002043375.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00381; match to protein family HMM PF00391; match to protein family HMM PF02896; match to protein family HMM PF05524; match to protein family HMM TIGR01417 YP_002043376.1 'FrwC with FrwB, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; forms translocation channel and contains the specific substrate-binding site' YP_002043377.1 'FrwB with FrwC, FrwD and PtsA forms a PEP-dependent sugar phosphotransferase system (PTS) permease which may phosphorylate and transport sugars into the cell; cytoplasmic protein that interacts with complex EIIA; contains the second phosphorylation site of the PTS' YP_002043378.1 involved in production of D-lactate from glucose under microaerobic conditions; cytoplasmic protein YP_002043379.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR02494 YP_002043380.1 'FrwD with FrwB, FrwC and PtsA forms a PEP-dependent sugar phosphotransferase system permease which may phosphorylate and transport sugars into the cell; phosphorylated by EIIA; FrwB homolog' YP_002043381.1 identified by match to protein family HMM PF00165 YP_002043382.1 identified by match to protein family HMM PF00884 YP_002043383.1 catalyzes the formation of oxaloacetate from phosphoenolpyruvate YP_002043384.1 catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis YP_002043385.1 'catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis and the reduction of N-acetyl-gamma-aminoadipyl-phosphate to N-acetyl-L-aminoadipate-semialdehyde in lysine biosynthesis; involved in both the arginine and lysine biosynthetic pathways; lysine is produced via the AAA pathway, lysine from alpha-aminoadipate' YP_002043386.1 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate YP_002043387.1 catalyzes the formation of arginine from (N-L-arginino)succinate YP_002043388.1 'Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA' YP_002043389.1 catalyzes the conversion of NADPH to NADH YP_002043390.1 identified by match to protein family HMM PF07226 YP_002043391.1 catalyzes the formation of 5-methyl-uridine at position 54 in all tRNAs YP_002043392.1 involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space YP_002043393.2 'converts L-glutamate to D-glutamate, a component of peptidoglycan' YP_002043394.1 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis YP_002043395.1 'catalyzes the formation of biotinyl-5'-AMP, also acts as a transcriptional repressor of the biotin operon' YP_002043396.1 catalyzes the formation of (R)-4'-phosphopantothenate in coenzyme A biosynthesis YP_002043398.1 'EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu' YP_002043399.1 'forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force' YP_002043400.1 Modulates Rho-dependent transcription termination YP_002043401.1 binds directly to 23S ribosomal RNA YP_002043402.1 'in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA' YP_002043403.1 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit YP_002043404.1 'present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors' YP_002043405.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme YP_002043406.1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter YP_002043407.1 'in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS; with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine, cysteine and 1-deoxy-D-xylulose-5-phosphate; forms a complex with ThiG; contains an iron-sulfur center' YP_002043408.1 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate YP_002043409.1 'with ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate' YP_002043410.1 identified by match to protein family HMM PF00899; match to protein family HMM PF05237; match to protein family HMM TIGR02356 YP_002043411.1 catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate YP_002043412.1 required for the synthesis of the hydromethylpyrimidine moiety of thiamine YP_002043413.1 binds specifically to the major sigma factor sigma 70; active in stationary phase YP_002043414.1 can catalyze hydrolysis of broad range of dinucleotide pyrophosphates but prefers reduced form of NADH; requires divalent metal ions such as magnesium and manganese and produces two mononucleoside 5'-phosphates YP_002043415.1 catalyzes the formation of coproporphyrinogen from uroporphyrinogen III YP_002043416.1 'Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA; cleaves DNA containing urea residues, AP sites, base mismatches, insertion/deletion mismatches, flaps, and pseudo-Y structures' YP_002043417.1 identified by match to protein family HMM PF04222 YP_002043418.1 histone-like DNA-binding protein YP_002043419.1 identified by match to protein family HMM PF07356 YP_002043421.1 identified by match to protein family HMM PF00512; match to protein family HMM PF02518 YP_002043422.1 DNA-binding response regulator in two-component regulatory system with ZraS; response regulator/sigma54 interaction protein YP_002043423.1 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis YP_002043424.1 involved in de novo purine biosynthesis YP_002043425.1 identified by match to protein family HMM PF00583 YP_002043426.1 catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis YP_002043427.1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle YP_002043428.1 identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346 YP_002043430.1 catalyzes the phosphorylation/dephosphorylation of the enzyme isocitrate dehydrogenase on a specific serine which regulates activity; unphosphorylated IDH is fully active when cells are grown on glucose while the enzyme becomes phosphorylated and inactive in the presence of acetate or ethanol YP_002043431.1 identified by match to protein family HMM PF04266 YP_002043432.1 'regulates the glyoxylate bypass operon (aceBAK), which encodes isocitrate lyase, malate synthase and isocitrate dehydrogenase kinase/phosphorylase' YP_002043433.1 identified by glimmer YP_002043434.1 one of two methionine synthases in Escherichia coli; MetH catalyzes a methyl transfer reaction from methyltetrahydrofolate to homocysteine to create methionine; requires zinc for activity YP_002043435.1 identified by match to protein family HMM PF02690; match to protein family HMM TIGR00704; match to protein family HMM TIGR01013 YP_002043436.1 alpha-aspartyl dipeptidase; catalyzes the hydrolysis of dipeptides with an N-terminal aspartate residue; belongs to peptidase S51 family YP_002043438.1 catalyzes the synthesis of pseudouridine from U-2604 in the 23S ribosomal RNA YP_002043440.1 identified by match to protein family HMM PF00455; match to protein family HMM PF08220; match to protein family HMM PF08279 YP_002043441.1 identified by match to protein family HMM PF00702; match to protein family HMM PF08282; match to protein family HMM TIGR00099; match to protein family HMM TIGR01484 YP_002043444.1 identified by match to protein family HMM PF02413 YP_002043445.1 identified by match to protein family HMM PF03406 YP_002043446.1 identified by match to protein family HMM PF09684; match to protein family HMM TIGR01634 YP_002043447.1 identified by match to protein family HMM PF04865 YP_002043448.1 identified by match to protein family HMM PF04965 YP_002043449.1 identified by glimmer YP_002043451.1 identified by match to protein family HMM PF00535 YP_002043452.1 identified by match to protein family HMM PF04138 YP_002043453.1 identified by glimmer YP_002043454.1 identified by match to protein family HMM PF04717; match to protein family HMM TIGR01644 YP_002043455.1 identified by match to protein family HMM PF05954 YP_002043456.1 identified by match to protein family HMM PF05489 YP_002043457.1 identified by match to protein family HMM PF06995 YP_002043458.1 identified by match to protein family HMM TIGR01760 YP_002043461.1 identified by match to protein family HMM PF04985; match to protein family HMM TIGR01611 YP_002043462.1 identified by match to protein family HMM PF04984 YP_002043464.1 identified by match to protein family HMM PF09646 YP_002043466.1 identified by match to protein family HMM PF01464 YP_002043468.1 identified by glimmer YP_002043469.1 identified by match to protein family HMM PF08765 YP_002043470.1 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP; functions in amino acid biosynthesis; lysine sensitive YP_002043471.1 functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family YP_002043474.1 identified by match to protein family HMM PF06251 YP_002043475.1 identified by match to protein family HMM PF06082 YP_002043476.1 identified by match to protein family HMM PF06146 YP_002043477.1 with MalKFE is involved in the transport of maltose into the cell YP_002043478.1 with MalKGE is involved in maltose transport into the cell YP_002043479.1 identified by glimmer YP_002043480.1 functions in the MalKFGE ABC transporter complex to transport maltose into the cell by using ATP hydrolysis YP_002043481.1 with malEFG is involved in import of maltose/maltodextrin YP_002043482.1 porin involved in the transport of maltose and maltodextrins YP_002043483.1 identified by match to protein family HMM PF07148 YP_002043484.1 catalyzes the formation of 4-hydroxybenzoate from chorismate YP_002043485.1 'catalyzes the conversion of 4-Hydroxybenzoate into 3-octaprenyl-4-hydroxybenzoate, as part of the ubiquinone biosynthesis pathway' YP_002043486.1 PlsB; catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA YP_002043487.1 identified by match to protein family HMM PF01219 YP_002043488.1 Represses a number of genes involved in the response to DNA damage YP_002043489.1 identified by match to protein family HMM PF01554; match to protein family HMM TIGR00797 YP_002043491.1 unknown function; highly abundant protein in vivo; overexpressed under high NaCl concentrations; part of the sigma S regulon; non-essential YP_002043492.1 'Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB' YP_002043494.1 identified by match to protein family HMM PF01207; match to protein family HMM TIGR00742 YP_002043495.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002043496.1 unwinds double stranded DNA YP_002043497.1 converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer YP_002043498.1 identified by glimmer YP_002043499.1 catalyzes the formation of L-glutamate and an aromatic oxo acid from an aromatic amino acid and 2-oxoglutarate YP_002043500.1 Class B; non-specific; catalyzes the dephosphorylation of organic phosphomonoesters; also has phosphotransferase activity YP_002043501.1 identified by match to protein family HMM PF01894; match to protein family HMM TIGR00149 YP_002043502.1 identified by match to protein family HMM PF04237 YP_002043505.1 'The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate' YP_002043506.1 binds to single stranded DNA and PriA helcase facilitate replication restart YP_002043507.1 identified by glimmer YP_002043508.1 identified by glimmer YP_002043511.1 identified by match to protein family HMM PF02321 YP_002043514.1 identified by match to protein family HMM PF00005 YP_002043515.1 identified by match to protein family HMM PF00563 YP_002043516.1 regulates genes involved in response to oxidative stress YP_002043517.1 identified by match to protein family HMM PF00376; match to protein family HMM PF09278; match to protein family HMM TIGR01950 YP_002043518.1 identified by match to protein family HMM PF00043; match to protein family HMM PF02798 YP_002043519.1 identified by glimmer YP_002043520.1 identified by match to protein family HMM PF00860; match to protein family HMM PF00916 YP_002043521.1 identified by match to protein family HMM PF00999; match to protein family HMM TIGR00831 YP_002043522.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002043523.1 identified by match to protein family HMM PF03788 YP_002043524.1 identified by match to protein family HMM PF04172 YP_002043525.1 member of the sodium:solute symporter family; cotranscribed with the acs gene which encodes acetyl coenzyme A synthase; mutations affect acetate uptake YP_002043526.1 identified by match to protein family HMM PF04341 YP_002043527.1 Acs; catalyzes the conversion of acetate and CoA to acetyl-CoA YP_002043528.1 catalyzes the formate-dependent reduction of nitrite to ammonia; cytochrome C552 YP_002043529.1 'part of nitrite reductase complex; NrfB is active at high nitrate conditions; NrfA, B, C, and D are essential for the formate-dependent nitrite reduction to ammonia' YP_002043530.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR01409; match to protein family HMM TIGR03149 YP_002043531.1 identified by match to protein family HMM PF03916; match to protein family HMM TIGR03148 YP_002043532.1 with NrfF and NrfG catalyzes the insertion of heme into cytochrome c552 YP_002043533.1 identified by match to protein family HMM PF07719 YP_002043534.1 'carrier protein part of the Na(+)-independent, binding-protein-independent glutamate-aspartate transport system' YP_002043535.1 identified by match to protein family HMM PF08238 YP_002043536.1 identified by match to protein family HMM PF05118 YP_002043537.1 PhnO in Salmonella enterica catalyzes the acetylation of a range of aminoalkylphosphonic acids; part of the biochemical pathway that enables the cell to use phosphonates as a phosphorus source; Escherichia coli uses a different mechanism of phosphonate catabolism where PhnO is not essential and seems to play a regulatory role YP_002043538.1 identified by match to protein family HMM PF00903; match to protein family HMM PF06983 YP_002043539.1 identified by match to protein family HMM PF03831; match to protein family HMM PF08274; match to protein family HMM TIGR00686 YP_002043540.1 identified by match to protein family HMM PF00083; match to protein family HMM PF07690; match to protein family HMM PF08946; match to protein family HMM TIGR00883 YP_002043541.1 identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518 YP_002043542.1 response regulator in two-component regulatory system with BasS YP_002043543.1 with ZipA and an unidentified 24 kDa protein forms a complex involved in cell division YP_002043544.1 identified by match to protein family HMM PF00324 YP_002043545.1 identified by match to protein family HMM PF00165 YP_002043546.1 identified by match to protein family HMM PF01276; match to protein family HMM PF03709; match to protein family HMM PF03711 YP_002043547.1 identified by match to protein family HMM PF00165 YP_002043548.1 identified by match to protein family HMM PF02056 YP_002043549.1 identified by match to protein family HMM TIGR00792 YP_002043550.1 identified by match to protein family HMM PF05681; match to protein family HMM PF05683; match to protein family HMM TIGR00722; match to protein family HMM TIGR00723 YP_002043551.1 'functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to DcuA; DcuA and DcuB function as independent and mutually redundant C4-dicarboxylate (aspartate, malate, fumarate and succinate) transporters' YP_002043553.1 response regulator in two-component regulatory system with DcuS; phosphorylated DcuR activates transcription of genes involved in anaerobic fumarate respiration YP_002043554.1 C4-dicarboxylate-sensing histidine kinase; part of two-component regulatory system with DcuR; regulates anaerobic fumarate respiration YP_002043555.1 identified by match to protein family HMM PF00384; match to protein family HMM PF01568; match to protein family HMM PF04879; match to protein family HMM TIGR01409; match to protein family HMM TIGR02166 YP_002043556.1 identified by match to protein family HMM PF00037; match to protein family HMM TIGR02951 YP_002043557.1 identified by match to protein family HMM PF04976 YP_002043558.1 identified by match to protein family HMM PF06192 YP_002043559.1 identified by match to protein family HMM PF09362 YP_002043561.1 identified by match to protein family HMM PF06977 YP_002043563.1 identified by match to protein family HMM PF00196 YP_002043564.1 identified by match to protein family HMM PF00165 YP_002043565.1 identified by glimmer YP_002043566.1 identified by match to protein family HMM PF08681 YP_002043567.1 identified by match to protein family HMM PF00583 YP_002043569.1 identified by glimmer YP_002043570.1 identified by match to protein family HMM PF03333 YP_002043571.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002043573.1 identified by glimmer YP_002043574.1 identified by glimmer YP_002043575.1 identified by match to protein family HMM PF01323 YP_002043576.1 identified by glimmer YP_002043577.1 identified by match to protein family HMM PF04703 YP_002043578.1 identified by glimmer YP_002043579.1 identified by match to protein family HMM PF06977 YP_002043580.1 identified by match to protein family HMM PF01569 YP_002043582.1 identified by match to protein family HMM PF00440 YP_002043583.1 two electrons are transferred from cytoplasmic NADPH to thioredoxin and then to the inner membrane protein DsbD which keeps the disulfide isomerase DsbC in a reduced state in the oxidizing periplasm; DsbC in turns rearranges incorrectly made disulfide bonds in the periplasm YP_002043584.1 copper binding protein required for copper tolerance; involved in resistance toward heavy metals YP_002043585.1 functions in anaerobic transport of C4-dicarboxylate compounds such as fumarate; similar to dcuB YP_002043586.1 catalyzes the formation of fumarate from aspartate YP_002043587.1 F exclusion of bacteriophage T7; overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7; interacts with the F plasmid-encoded PifA protein; inner membrane protein YP_002043588.1 uncharacterized member of the APC superfamily of amino acid transporters; unknown function YP_002043589.1 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring YP_002043590.1 '60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth' YP_002043593.1 identified by match to protein family HMM PF04055; match to protein family HMM TIGR00238 YP_002043594.1 Involved in peptide bond synthesis; alters the affinity of the ribosome for aminoacyl-tRNA YP_002043595.1 identified by match to protein family HMM PF08085 YP_002043597.1 lipocalin; globomycin-sensitive outer membrane lipoprotein YP_002043598.1 in conjunction with FrdC acts to anchor the catalytic components of the fumarate reductase to the cytoplasmic membrane YP_002043599.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002043600.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002043601.1 'part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB' YP_002043602.1 lysine--tRNA ligase beta chain; poxA; class II aminoacyl tRNA synthetase; catalyzes a two-step reaction; first charging a lysine molecule by linking the carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA YP_002043603.1 identified by match to protein family HMM PF00324 YP_002043605.1 identified by match to protein family HMM PF00924 YP_002043606.1 catalyzes the decarboxylation of phosphatidyl-L-serine to phosphatidylethanoleamine YP_002043607.1 EngC; RsgA; CpgA; circularly permuted GTPase; ribosome small subunit-dependent GTPase A; has the pattern G4-G1-G3 as opposed to other GTPases; interacts strongly with 30S ribosome which stimulates GTPase activity YP_002043608.1 3'-5' exoribonuclease specific for small oligoribonuclotides YP_002043609.1 identified by match to protein family HMM PF00497 YP_002043610.1 identified by match to protein family HMM PF08331; match to protein family HMM TIGR00276 YP_002043611.1 identified by match to protein family HMM PF01256; match to protein family HMM PF03853; match to protein family HMM TIGR00196; match to protein family HMM TIGR00197 YP_002043612.1 possibly involved in cell wall synthesis YP_002043613.1 identified by match to protein family HMM PF01520 YP_002043614.1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. Promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex YP_002043615.1 IPP transferase; isopentenyltransferase; involved in tRNA modification; in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil; further tRNA modifications may occur; mutations in miaA result in defects in translation efficiency and fidelity YP_002043616.1 Stimulates the elongation of poly(A) tails YP_002043617.1 involved in modulation of proteins HflK and HflC; part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein YP_002043618.1 with HflC inhibits proteolysis of lambda cII protein by FtsH YP_002043619.1 with HflK inhibits proteolysis of lambda cII protein by FtsH YP_002043621.1 'catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis' YP_002043622.2 negatively regulates the transcription of genes upregulated by nitrosative stress YP_002043623.1 '3'-5'exoribonuclease that acts nonspecifically on poly(A), poly(U) and ribosomal RNAs' YP_002043624.1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA YP_002043626.1 identified by match to protein family HMM PF04012 YP_002043628.1 identified by match to protein family HMM PF03994 YP_002043629.1 identified by match to protein family HMM PF06693 YP_002043630.1 identified by match to protein family HMM PF03738 YP_002043631.1 catalyzes the formation of 3-methylcrotonyl-CoA from isovaleryl-CoA YP_002043632.1 identified by match to protein family HMM PF07338 YP_002043633.1 'in Escherichia coli, mutation of this gene affects biofilm maturation, stress response, and motility' YP_002043634.1 YjfP; esterase activity towards palmitoyl-CoA and pNP-butyrate in vitro; unknown function and substrate in vivo YP_002043635.1 negative regulator of ulaG and ulaABCDEF YP_002043637.1 membrane component; functions with enzymes IIB (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for anaerobic utilization and uptake of L-ascorbate; sgaTBA are regulated by yifQ as well as Crp and Fnr YP_002043638.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002043639.1 involved in the phosphorylation and transport of sugars across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake YP_002043640.1 catalyzes the formation of L-xylulose-5-phosphate from 3-keto-L-gulonate-6-phosphate in anaerobic L-ascorbate utilization YP_002043641.1 UlaE; catalyzes the epimerization of L-ribulose-5-phosphate into L-xylulose-5-phosphate; part of the anaerobic L-ascorbate degradation pathway YP_002043642.1 catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate in the anaerobic catabolism of L-ascorbate; links the arabinose metabolic pathway to the pentose phosphate pathway and allows the bacteria to use arabinose as an energy source YP_002043643.1 identified by match to protein family HMM PF07338 YP_002043644.1 'binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21' YP_002043645.1 binds single-stranded DNA at the primosome assembly site YP_002043646.1 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit YP_002043647.1 in Escherichia coli this protein is wrapped around the base of the L1 stalk YP_002043648.1 identified by match to protein family HMM PF00892 YP_002043649.1 identified by match to protein family HMM PF04225; match to protein family HMM PF08525 YP_002043650.1 FKBP-type; rotamase; catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides YP_002043651.1 identified by glimmer YP_002043652.1 'involved in the transport across the cytoplasmic membrane of D-alanine, D-serine and glycine' YP_002043655.1 Involved in anaerobic NO protection and iron metabolism YP_002043656.1 identified by match to protein family HMM PF00892 YP_002043657.1 identified by match to protein family HMM PF01073; match to protein family HMM PF02254; match to protein family HMM PF05368; match to protein family HMM PF07993 YP_002043658.1 'periplasmic enzyme; functions during ribonucleic acid degradation; 2',3'-cyclic nucleotides are first converted to 3'-nucleotide and then cleaved to yield a ribonucleotide and a phosphate' YP_002043659.1 identified by glimmer YP_002043660.1 'catalyzes the formation of AMP from adenosine-3',5'-bisphosphate' YP_002043661.1 identified by match to protein family HMM PF09695; match to protein family HMM TIGR01626 YP_002043662.1 identified by match to protein family HMM PF06526 YP_002043663.1 identified by match to protein family HMM PF00571; match to protein family HMM PF01595; match to protein family HMM PF03471 YP_002043664.1 this stereospecific enzymes reduces the S isomer of methionine sulfoxide while MsrB reduces the R form; provides protection against oxidative stress YP_002043666.1 identified by match to protein family HMM PF01103; match to protein family HMM PF07244 YP_002043667.1 identified by match to protein family HMM PF04357 YP_002043668.1 identified by match to protein family HMM PF06094 YP_002043669.1 identified by match to protein family HMM PF07690 YP_002043670.1 identified by match to protein family HMM PF01979 YP_002043671.1 catalyzes the hydrolysis of pyrophosphate to phosphate YP_002043672.1 'catalyzes the formation of D-fructose 6-phosphate from fructose-1,6-bisphosphate' YP_002043673.1 identified by match to protein family HMM PF01225; match to protein family HMM PF02875; match to protein family HMM PF08245; match to protein family HMM TIGR01081 YP_002043674.1 identified by match to protein family HMM PF04751 YP_002043675.1 protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD YP_002043676.1 identified by match to protein family HMM PF07361 YP_002043678.1 identified by match to protein family HMM PF00874; match to protein family HMM TIGR03582 YP_002043679.1 identified by match to protein family HMM TIGR03577 YP_002043680.1 identified by match to protein family HMM TIGR03578 YP_002043681.1 identified by match to protein family HMM TIGR03580 YP_002043682.1 identified by match to protein family HMM TIGR03579 YP_002043683.1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides YP_002043684.1 identified by match to protein family HMM PF01212; match to protein family HMM PF03841; match to protein family HMM TIGR01437 YP_002043685.1 identified by match to protein family HMM PF07071; match to protein family HMM TIGR03581 YP_002043686.1 identified by match to protein family HMM PF00359; match to protein family HMM PF00874; match to protein family HMM PF05043; match to protein family HMM PF08279 YP_002043687.1 Qin prophage; bifunctional antitoxin of the RelE-RelB toxin-antitoxin system/transcriptional repressor YP_002043688.1 identified by match to protein family HMM PF05016; match to protein family HMM TIGR02385 YP_002043689.1 activates anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions YP_002043690.1 Catalyzes the reduction of nucleoside 5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates YP_002043692.1 identified by match to protein family HMM PF00128; match to protein family HMM TIGR02403 YP_002043693.1 phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel YP_002043694.1 regulates genes involved in trehalose metabolism; binds the intermediate trehalose-6-phosphate; binds a dimer; regulates treBC operon YP_002043696.1 P-type ATPase involved in magnesium influx YP_002043697.1 identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004 YP_002043698.1 involved in the allosteric regulation of aspartate carbamoyltransferase YP_002043699.1 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis YP_002043700.1 identified by match to protein family HMM PF01316; match to protein family HMM PF02863 YP_002043701.1 identified by glimmer YP_002043702.1 identified by match to protein family HMM PF03606 YP_002043703.1 catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway YP_002043705.1 reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP YP_002043706.1 catalyzes the degradation of arginine to citruline and ammonia YP_002043708.1 identified by match to protein family HMM PF04074; match to protein family HMM TIGR00022 YP_002043709.1 'catalyzes the formation of L-citrulline from carbamoyl phosphate and L-ornithine in arginine biosynthesis and degradation; E. coli K12 has two genes, argF and argI, capable of producing functional ornithine carbamoyltransferase. When both are active in the same cell, the two gene products form a family of four hybrid trimeric isoenzymes designated, FFF, FFI, FII, and III.' YP_002043710.1 identified by match to protein family HMM PF06877 YP_002043711.1 identified by match to protein family HMM PF06175 YP_002043713.1 identified by match to protein family HMM PF00583 YP_002043714.1 identified by match to protein family HMM PF05987 YP_002043715.1 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain YP_002043716.1 binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002043717.1 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides YP_002043718.1 identified by match to protein family HMM PF03739 YP_002043719.1 identified by match to protein family HMM PF03739 YP_002043720.1 identified by match to protein family HMM PF00356; match to protein family HMM PF00532 YP_002043721.1 identified by match to protein family HMM PF02447; match to protein family HMM PF03600; match to protein family HMM PF06808; match to protein family HMM TIGR00791 YP_002043722.1 'Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate' YP_002043723.1 NAD-binding YP_002043724.1 identified by match to protein family HMM PF01202; match to protein family HMM TIGR01313 YP_002043725.1 identified by match to protein family HMM PF00107; match to protein family HMM PF08240 YP_002043726.1 identified by match to protein family HMM PF00589 YP_002043727.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271 YP_002043730.1 encoded in CP-933I; identified by match to protein family HMM PF07455 YP_002043732.1 identified by match to protein family HMM PF05930 YP_002043733.1 identified by glimmer YP_002043737.1 identified by match to protein family HMM PF03288; match to protein family HMM PF08273; match to protein family HMM PF08706; match to protein family HMM TIGR01613 YP_002043738.1 identified by match to protein family HMM PF01709; match to protein family HMM TIGR01033 YP_002043739.1 identified by glimmer YP_002043740.1 identified by match to protein family HMM PF08241; match to protein family HMM PF08242 YP_002043743.1 identified by match to protein family HMM PF06353 YP_002043747.1 identified by match to protein family HMM PF03625 YP_002043748.1 identified by match to protein family HMM PF01738 YP_002043749.1 regulates the expression of uxuBA YP_002043750.1 'catalyzes a two-step reaction, first charging a tryptophan molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA' YP_002043751.2 identified by match to protein family HMM PF05638 YP_002043752.1 identified by glimmer YP_002043753.1 identified by match to protein family HMM PF01177; match to protein family HMM TIGR00035 YP_002043754.1 identified by match to protein family HMM PF00126; match to protein family HMM PF03466 YP_002043755.1 identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01975 YP_002043756.1 identified by match to protein family HMM PF07670 YP_002043757.1 identified by match to protein family HMM PF07670 YP_002043758.1 identified by match to protein family HMM PF06779; match to protein family HMM PF07690 YP_002043759.1 identified by match to protein family HMM PF04286 YP_002043760.1 identified by match to protein family HMM PF07690 YP_002043761.1 identified by glimmer YP_002043762.1 identified by match to protein family HMM PF04754; match to protein family HMM TIGR01784 YP_002043764.1 identified by match to protein family HMM PF00171 YP_002043766.1 identified by match to protein family HMM PF03235 YP_002043767.1 involved in the degradation of RNA; may be involved in the recycling of RNA during the SOS response YP_002043768.1 identified by match to protein family HMM PF01420 YP_002043769.1 identified by match to protein family HMM PF01170; match to protein family HMM PF02384 YP_002043770.1 identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM PF08463 YP_002043772.1 identified by match to protein family HMM PF02492; match to protein family HMM PF07683 YP_002043773.1 identified by match to protein family HMM PF04328 YP_002043774.1 identified by match to protein family HMM PF02554 YP_002043775.1 identified by match to protein family HMM PF00015; match to protein family HMM PF00672; match to protein family HMM PF02203 YP_002043777.1 identified by match to protein family HMM PF00158; match to protein family HMM PF00874 YP_002043778.1 identified by match to protein family HMM PF03610 YP_002043779.1 identified by match to protein family HMM PF03830 YP_002043780.1 identified by match to protein family HMM PF03609 YP_002043781.1 identified by match to protein family HMM PF03613 YP_002043782.1 identified by match to protein family HMM PF01380 YP_002043783.1 identified by match to protein family HMM PF01380 YP_002043784.1 catalyzes the transfer of phosphoglycerol to the glucan backbone YP_002043786.1 acts to load the DnaB helicase onto the initiation site during DNA replication YP_002043787.1 'This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with dnaB protein and other prepriming proteins dnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'' YP_002043789.1 identified by match to protein family HMM PF06738 YP_002043791.1 identified by match to protein family HMM PF00196 YP_002043792.1 regulator for the transport and utilization of the aromatic beta-glucosides arbutin and silicin YP_002043793.1 identified by match to protein family HMM PF04073 YP_002043794.1 identified by match to protein family HMM PF06276 YP_002043795.2 identified by match to protein family HMM PF00990; match to protein family HMM TIGR00254 YP_002043796.1 identified by match to protein family HMM PF07256 YP_002043797.1 16S rRNA M2G1207 methyltransferase; one of many enzymes that modify bases of the ribosomal RNA; this enzyme methylates the G at position 1207 of the small ribosomal subunit YP_002043798.1 with the chi subunit binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB YP_002043799.2 identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575 YP_002043800.1 'manganese-dependent 5'-nucleotidase; specific for 5'-UMP, 5'-dUMP, and 5'-dTMP; member of haloacid dehalogenase (HAD)-like hydrolase superfamily' YP_002043801.1 stimulates the release of release factors 1 and 2 from the ribosome after hydrolysis of the ester bond in peptidyl-tRNA has occurred; GDP/GTP-binding protein YP_002043802.1 identified by match to protein family HMM PF04972 YP_002043803.1 identified by glimmer YP_002043804.1 identified by match to protein family HMM PF01734 YP_002043805.1 identified by match to protein family HMM PF01026 YP_002043808.1 catalyzes the formation of D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-D-ribose-5-phosphate YP_002043809.1 'Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate' YP_002043810.1 catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose YP_002043811.1 catalyzes the reversible phosphorolysis of ribonucleosides and 2'- deoxyribonucleosides to the free base and (2'-deoxy)ribose-1- phosphate YP_002043813.1 identified by match to protein family HMM PF00577 YP_002043814.1 member of the periplasmic pilus chaperone family of proteins YP_002043815.1 identified by match to protein family HMM PF06551 YP_002043816.1 identified by match to protein family HMM PF06551 YP_002043817.1 identified by glimmer YP_002043818.1 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl on the lipoate-dependent enzymes. Creates an amide linkage that joins the free carboxyl group of lipoic acid to the epsilon-amino group of a specific lysine residue in lipoyl domain of apoproteins YP_002043820.1 catalyzes the formation of serine from O-phosphoserine YP_002043821.1 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents YP_002043822.1 catalyzes the formation of NAD(+) from nicotinamide ribonucleotide YP_002043823.1 'ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence' YP_002043824.1 catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan YP_002043825.1 When complexed with L-tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription YP_002043826.1 pyrophosphatase; has activity against dUTP and dITP; the crystal structure of the Vibrio protein showed similarity to Methanococcus janaschii Mj0226; in Vibrio cholerae this gene is part of the Mba operon that is involved in regulation and maintenance of biofilms; in Escherichia coli overexpression of this gene leads to resistance to an HMP analog YP_002043827.1 catalyzes reactions involving the transfer of phospho groups between the three carbon atoms of phosphoglycerate YP_002043828.1 identified by match to protein family HMM PF00165; match to protein family HMM PF06445 YP_002043829.1 identified by match to protein family HMM PF05981 YP_002043830.1 response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation YP_002043831.1 part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation YP_002043832.1 identified by match to protein family HMM PF06123 YP_002043833.1 identified by match to protein family HMM PF00419 YP_002043834.1 identified by match to protein family HMM PF00419 YP_002043835.2 identified by match to protein family HMM PF00577 YP_002043836.1 identified by match to protein family HMM PF00345; match to protein family HMM PF02753 YP_002043837.1 identified by match to protein family HMM PF00419 YP_002043839.1 identified by match to protein family HMM PF00072; match to protein family HMM PF00486 YP_002043840.1 member of the SPOUT superfamily of methyltransferases